LOCUS       DAZKCW010000001        92148 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000001 DAZKCW010000000
VERSION     DAZKCW010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 92148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.001"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..450)
                     /locus_tag="ACG84Z_000001"
     CDS             complement(<1..450)
                     /locus_tag="ACG84Z_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9160889.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLI"
     gene            416..2053
                     /locus_tag="ACG84Z_000002"
     CDS             416..2053
                     /locus_tag="ACG84Z_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9160890.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2198..2938)
                     /gene="truA"
                     /locus_tag="ACG84Z_000003"
     CDS             complement(2198..2938)
                     /gene="truA"
                     /locus_tag="ACG84Z_000003"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFP9160891.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3129..3764)
                     /locus_tag="ACG84Z_000004"
     CDS             complement(3129..3764)
                     /locus_tag="ACG84Z_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFP9160892.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3911..5131)
                     /gene="sstT"
                     /locus_tag="ACG84Z_000005"
     CDS             complement(3911..5131)
                     /gene="sstT"
                     /locus_tag="ACG84Z_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFP9160893.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            5350..6348
                     /locus_tag="ACG84Z_000006"
     CDS             5350..6348
                     /locus_tag="ACG84Z_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9160894.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            6544..8379
                     /locus_tag="ACG84Z_000007"
     CDS             6544..8379
                     /locus_tag="ACG84Z_000007"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFP9160895.1"
                     /translation="MQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLL
                     LLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVSPVL
                     LIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSP
                     SFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYN
                     TKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLM
                     LSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHP
                     FTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNT
                     ETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKF
                     IQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNK
                     EVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTE
                     DSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8439..9155)
                     /locus_tag="ACG84Z_000008"
     CDS             complement(8439..9155)
                     /locus_tag="ACG84Z_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFP9160896.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(9382..9924)
                     /locus_tag="ACG84Z_000009"
     CDS             complement(9382..9924)
                     /locus_tag="ACG84Z_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFP9160897.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(9929..10156)
                     /locus_tag="ACG84Z_000010"
     CDS             complement(9929..10156)
                     /locus_tag="ACG84Z_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFP9160898.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(10235..12115)
                     /locus_tag="ACG84Z_000011"
     CDS             complement(10235..12115)
                     /locus_tag="ACG84Z_000011"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9160899.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(12304..12918)
                     /locus_tag="ACG84Z_000012"
     CDS             complement(12304..12918)
                     /locus_tag="ACG84Z_000012"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9160900.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            13060..13620
                     /locus_tag="ACG84Z_000013"
     CDS             13060..13620
                     /locus_tag="ACG84Z_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9160901.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(13925..14239)
                     /locus_tag="ACG84Z_000014"
                     /pseudo
     CDS             complement(13925..14239)
                     /locus_tag="ACG84Z_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(14493..16128)
                     /locus_tag="ACG84Z_000015"
                     /pseudo
     CDS             complement(14493..16128)
                     /locus_tag="ACG84Z_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16451..16930)
                     /gene="rlmH"
                     /locus_tag="ACG84Z_000016"
     CDS             complement(16451..16930)
                     /gene="rlmH"
                     /locus_tag="ACG84Z_000016"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFP9160902.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            17358..18647
                     /locus_tag="ACG84Z_000017"
     CDS             17358..18647
                     /locus_tag="ACG84Z_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFP9160903.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(18686..19291)
                     /gene="ytpR"
                     /locus_tag="ACG84Z_000018"
     CDS             complement(18686..19291)
                     /gene="ytpR"
                     /locus_tag="ACG84Z_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFP9160904.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(19496..19960)
                     /locus_tag="ACG84Z_000019"
     CDS             complement(19496..19960)
                     /locus_tag="ACG84Z_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFP9160905.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(19982..20302)
                     /locus_tag="ACG84Z_000020"
     CDS             complement(19982..20302)
                     /locus_tag="ACG84Z_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFP9160906.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(20446..21525)
                     /gene="pepA"
                     /locus_tag="ACG84Z_000021"
     CDS             complement(20446..21525)
                     /gene="pepA"
                     /locus_tag="ACG84Z_000021"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFP9160907.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            21725..22075
                     /locus_tag="ACG84Z_000022"
     CDS             21725..22075
                     /locus_tag="ACG84Z_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFP9160908.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            22298..23245
                     /locus_tag="ACG84Z_000023"
     CDS             22298..23245
                     /locus_tag="ACG84Z_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9160909.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(23302..24720)
                     /gene="pepV"
                     /locus_tag="ACG84Z_000024"
     CDS             complement(23302..24720)
                     /gene="pepV"
                     /locus_tag="ACG84Z_000024"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFP9160910.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            24869..25714
                     /locus_tag="ACG84Z_000025"
     CDS             24869..25714
                     /locus_tag="ACG84Z_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFP9160911.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            25718..26158
                     /locus_tag="ACG84Z_000026"
     CDS             25718..26158
                     /locus_tag="ACG84Z_000026"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFP9160912.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            26208..26402
                     /locus_tag="ACG84Z_000027"
     CDS             26208..26402
                     /locus_tag="ACG84Z_000027"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9160913.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            26538..27223
                     /locus_tag="ACG84Z_000028"
                     /pseudo
     CDS             26538..27223
                     /locus_tag="ACG84Z_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(27631..28320)
                     /locus_tag="ACG84Z_000029"
     CDS             complement(27631..28320)
                     /locus_tag="ACG84Z_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9160914.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(28295..30431)
                     /locus_tag="ACG84Z_000030"
                     /pseudo
     CDS             complement(28295..30431)
                     /locus_tag="ACG84Z_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
     gene            complement(30479..31816)
                     /locus_tag="ACG84Z_000031"
     CDS             complement(30479..31816)
                     /locus_tag="ACG84Z_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFP9160915.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(32068..32427)
                     /gene="rplT"
                     /locus_tag="ACG84Z_000032"
     CDS             complement(32068..32427)
                     /gene="rplT"
                     /locus_tag="ACG84Z_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFP9160916.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(32480..32680)
                     /gene="rpmI"
                     /locus_tag="ACG84Z_000033"
     CDS             complement(32480..32680)
                     /gene="rpmI"
                     /locus_tag="ACG84Z_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFP9160917.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(32752..33276)
                     /gene="infC"
                     /locus_tag="ACG84Z_000034"
     CDS             complement(32752..33276)
                     /gene="infC"
                     /locus_tag="ACG84Z_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFP9160918.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(33320..33445)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            33598..34230
                     /locus_tag="ACG84Z_000035"
     CDS             33598..34230
                     /locus_tag="ACG84Z_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFP9160919.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(34232..35137)
                     /locus_tag="ACG84Z_000036"
     CDS             complement(34232..35137)
                     /locus_tag="ACG84Z_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFP9160920.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(35222..35881)
                     /locus_tag="ACG84Z_000037"
     CDS             complement(35222..35881)
                     /locus_tag="ACG84Z_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFP9160921.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            36197..37141
                     /gene="mvk"
                     /locus_tag="ACG84Z_000038"
     CDS             36197..37141
                     /gene="mvk"
                     /locus_tag="ACG84Z_000038"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFP9160922.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            37134..38111
                     /gene="mvaD"
                     /locus_tag="ACG84Z_000039"
     CDS             37134..38111
                     /gene="mvaD"
                     /locus_tag="ACG84Z_000039"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFP9160923.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            38124..39209
                     /locus_tag="ACG84Z_000040"
     CDS             38124..39209
                     /locus_tag="ACG84Z_000040"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFP9160924.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            39206..40270
                     /gene="fni"
                     /locus_tag="ACG84Z_000041"
     CDS             39206..40270
                     /gene="fni"
                     /locus_tag="ACG84Z_000041"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFP9160925.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(40519..41322)
                     /locus_tag="ACG84Z_000042"
     CDS             complement(40519..41322)
                     /locus_tag="ACG84Z_000042"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFP9160926.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(41342..42184)
                     /gene="kduI"
                     /locus_tag="ACG84Z_000043"
     CDS             complement(41342..42184)
                     /gene="kduI"
                     /locus_tag="ACG84Z_000043"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HFP9160927.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(42200..43207)
                     /locus_tag="ACG84Z_000044"
     CDS             complement(42200..43207)
                     /locus_tag="ACG84Z_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HFP9160928.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(43214..43858)
                     /locus_tag="ACG84Z_000045"
     CDS             complement(43214..43858)
                     /locus_tag="ACG84Z_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFP9160929.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(43958..44716)
                     /locus_tag="ACG84Z_000046"
     CDS             complement(43958..44716)
                     /locus_tag="ACG84Z_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFP9160930.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(44843..45994)
                     /gene="fucO"
                     /locus_tag="ACG84Z_000047"
     CDS             complement(44843..45994)
                     /gene="fucO"
                     /locus_tag="ACG84Z_000047"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HFP9160931.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(46076..46387)
                     /gene="rhaM"
                     /locus_tag="ACG84Z_000048"
     CDS             complement(46076..46387)
                     /gene="rhaM"
                     /locus_tag="ACG84Z_000048"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HFP9160932.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(46389..47234)
                     /gene="rhaD"
                     /locus_tag="ACG84Z_000049"
     CDS             complement(46389..47234)
                     /gene="rhaD"
                     /locus_tag="ACG84Z_000049"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HFP9160933.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(47248..48504)
                     /gene="rhaA"
                     /locus_tag="ACG84Z_000050"
     CDS             complement(47248..48504)
                     /gene="rhaA"
                     /locus_tag="ACG84Z_000050"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HFP9160934.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(48501..49961)
                     /gene="rhaB"
                     /locus_tag="ACG84Z_000051"
     CDS             complement(48501..49961)
                     /gene="rhaB"
                     /locus_tag="ACG84Z_000051"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HFP9160935.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            50114..50983
                     /locus_tag="ACG84Z_000052"
     CDS             50114..50983
                     /locus_tag="ACG84Z_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFP9160936.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(51109..52008)
                     /locus_tag="ACG84Z_000053"
     CDS             complement(51109..52008)
                     /locus_tag="ACG84Z_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9160937.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(52173..52997)
                     /locus_tag="ACG84Z_000054"
     CDS             complement(52173..52997)
                     /locus_tag="ACG84Z_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFP9160938.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(53008..54303)
                     /locus_tag="ACG84Z_000055"
     CDS             complement(53008..54303)
                     /locus_tag="ACG84Z_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFP9160939.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(54319..54798)
                     /locus_tag="ACG84Z_000056"
     CDS             complement(54319..54798)
                     /locus_tag="ACG84Z_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFP9160940.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(54804..55832)
                     /locus_tag="ACG84Z_000057"
     CDS             complement(54804..55832)
                     /locus_tag="ACG84Z_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFP9160941.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(55849..56955)
                     /locus_tag="ACG84Z_000058"
     CDS             complement(55849..56955)
                     /locus_tag="ACG84Z_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFP9160942.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(57184..59781)
                     /gene="adhE"
                     /locus_tag="ACG84Z_000059"
                     /gene_synonym="adhC"
     CDS             complement(57184..59781)
                     /gene="adhE"
                     /locus_tag="ACG84Z_000059"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFP9160943.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(60086..60466)
                     /gene="yajC"
                     /locus_tag="ACG84Z_000060"
     CDS             complement(60086..60466)
                     /gene="yajC"
                     /locus_tag="ACG84Z_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFP9160944.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(60563..61708)
                     /gene="tgt"
                     /locus_tag="ACG84Z_000061"
     CDS             complement(60563..61708)
                     /gene="tgt"
                     /locus_tag="ACG84Z_000061"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFP9160945.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            61926..62624
                     /locus_tag="ACG84Z_000062"
     CDS             61926..62624
                     /locus_tag="ACG84Z_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFP9160946.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(62792..65431)
                     /locus_tag="ACG84Z_000063"
     CDS             complement(62792..65431)
                     /locus_tag="ACG84Z_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFP9160947.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(66050..67081)
                     /gene="queA"
                     /locus_tag="ACG84Z_000064"
     CDS             complement(66050..67081)
                     /gene="queA"
                     /locus_tag="ACG84Z_000064"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFP9160948.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            67274..68449
                     /locus_tag="ACG84Z_000065"
     CDS             67274..68449
                     /locus_tag="ACG84Z_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HFP9160949.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            68453..69094
                     /locus_tag="ACG84Z_000066"
     CDS             68453..69094
                     /locus_tag="ACG84Z_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9160950.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            69091..70008
                     /locus_tag="ACG84Z_000067"
     CDS             69091..70008
                     /locus_tag="ACG84Z_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9160951.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            70005..70676
                     /locus_tag="ACG84Z_000068"
     CDS             70005..70676
                     /locus_tag="ACG84Z_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9160952.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(71217..71705)
                     /locus_tag="ACG84Z_000069"
     CDS             complement(71217..71705)
                     /locus_tag="ACG84Z_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFP9160953.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(71906..72172)
                     /locus_tag="ACG84Z_000070"
     CDS             complement(71906..72172)
                     /locus_tag="ACG84Z_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFP9160954.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(72172..72435)
                     /locus_tag="ACG84Z_000071"
     CDS             complement(72172..72435)
                     /locus_tag="ACG84Z_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFP9160955.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            72956..73096
                     /locus_tag="ACG84Z_000072"
                     /pseudo
     CDS             72956..73096
                     /locus_tag="ACG84Z_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(73238..75061)
                     /locus_tag="ACG84Z_000073"
     CDS             complement(73238..75061)
                     /locus_tag="ACG84Z_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFP9160956.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(75659..78364)
                     /locus_tag="ACG84Z_000074"
     CDS             complement(75659..78364)
                     /locus_tag="ACG84Z_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFP9160957.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(78670..79617)
                     /locus_tag="ACG84Z_000075"
     CDS             complement(78670..79617)
                     /locus_tag="ACG84Z_000075"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFP9160958.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            79807..80076
                     /gene="rpsN"
                     /locus_tag="ACG84Z_000076"
     CDS             79807..80076
                     /gene="rpsN"
                     /locus_tag="ACG84Z_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFP9160959.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(80252..80614)
                     /locus_tag="ACG84Z_000077"
     CDS             complement(80252..80614)
                     /locus_tag="ACG84Z_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFP9160960.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(80625..81746)
                     /gene="alr"
                     /locus_tag="ACG84Z_000078"
     CDS             complement(80625..81746)
                     /gene="alr"
                     /locus_tag="ACG84Z_000078"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFP9160961.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(81762..82112)
                     /gene="acpS"
                     /locus_tag="ACG84Z_000079"
     CDS             complement(81762..82112)
                     /gene="acpS"
                     /locus_tag="ACG84Z_000079"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFP9160962.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(82242..83753)
                     /locus_tag="ACG84Z_000080"
     CDS             complement(82242..83753)
                     /locus_tag="ACG84Z_000080"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFP9160963.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(84075..85427)
                     /gene="murF"
                     /locus_tag="ACG84Z_000081"
     CDS             complement(84075..85427)
                     /gene="murF"
                     /locus_tag="ACG84Z_000081"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFP9160964.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(85580..86656)
                     /locus_tag="ACG84Z_000082"
     CDS             complement(85580..86656)
                     /locus_tag="ACG84Z_000082"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFP9160965.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            86852..88597
                     /locus_tag="ACG84Z_000083"
     CDS             86852..88597
                     /locus_tag="ACG84Z_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFP9160966.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(88877..89314)
                     /locus_tag="ACG84Z_000084"
     CDS             complement(88877..89314)
                     /locus_tag="ACG84Z_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFP9160967.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(89298..90671)
                     /locus_tag="ACG84Z_000085"
     CDS             complement(89298..90671)
                     /locus_tag="ACG84Z_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9160968.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(90993..91481)
                     /locus_tag="ACG84Z_000086"
     CDS             complement(90993..91481)
                     /locus_tag="ACG84Z_000086"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9160969.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(91503..92105)
                     /locus_tag="ACG84Z_000087"
     CDS             complement(91503..92105)
                     /locus_tag="ACG84Z_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFP9160970.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        26909 a        19327 c        16460 g        29452 t
ORIGIN      
        1 tattaagtta tttgaaattc cataaaaaac gactgcagga attattgtaa gaaaaggata
       61 aaaatagttc agtccatctc cataattgtt aaatgttgta tagttgattg gcccttcaaa
      121 aatagaagat aaccctttga ttcgtgaaag atgaaaagat aaatcacctg ttgtataaat
      181 ttcttgagca tttctcataa aatttactga atataaagta ctaagtaaga taagaactac
      241 taaaagaaat gcttttttac ttattttcat agatttgttg ttctcctttt ttaattctat
      301 tttcagtata ctagaattgt ctttttttaa taagttttgc gttaaatttt tcatagcact
      361 agtatgatat actagaaaag aatcaatttt tattactttt aaataggaga aaaaaatgaa
      421 aaaaaacaaa aaccaaataa tagatatcat ttttatgtta tttctaagtt ttgcttacgt
      481 catccctcta ttcatgtcta agggaatcta tcatagtgtc aatcaggata cttactttca
      541 tttatctcga atcataggac tagataatgt atggagttct ccagtaaact tcaataactt
      601 cgatcatcat ggaacaatga tgaatatttt ttatccatgg cttactcttt atccagcttt
      661 tttattttat aaaatgatgg gaaatcttgt tttaagttat aatatctact atttttttat
      721 cactttttta acaatggtcg tttcttattt ttctatgaaa caaataaaaa acaatcgtta
      781 tatttcgctg ttattttcga ttatttatac attttccgcc tatcgtgcca ttgacatatt
      841 ccatcgtgct tcattgggag aagctgtcgc tttaacattt ttgcctttga tactaatggg
      901 gtgttacgaa atttatatta gagattacca aaaatggtac tggttgtcta ttggcatgac
      961 gctagtagtg tatactcatt tactttctgt cgctatggtt tctgtattta ttggaggaac
     1021 gttgtttctt tctttttatt tttgggacca aaaaatcgct agactcttaa gtcttttaaa
     1081 agctaccgtc ctcacctttt ttttaagtgc gggattctta attcctttta ttcaacaatc
     1141 tagagcacaa gaattgaaag tcccactggg aaaagaatta agtggtatgg ctcctagtga
     1201 tatgctgaca catattttaa ataataacta taacaactat actattggat tattcttatt
     1261 tctcggattg attggtgctt ttatttttat aaaaaaatta actgctgatg atttatttat
     1321 tttctttctt ggtgtatttg ttcttttttg ttcaaccaat ttatttcctt ggcaactttt
     1381 taaccataca ccagttaaga gtctacaatt tgtctggcgg ttaaatggtt tttcttcttt
     1441 atttatagcc tatacgatga gtatagtgat ctattatatt ttttctacta aaaataattc
     1501 atggaaaata atggtcttta cgtttcttgc actaatattg catctctcag gagtaagcaa
     1561 ttctatccat gctaacaaag attcattaac acttatagca cctgaagacg ctgttgctat
     1621 agctgaaaat tacaatcata ctgattatgc aaacaaagag tcaatctatc atcctgatat
     1681 gattaataat gatcaatatt tactaggtaa ccaggaaata aatccaacaa ctcattttat
     1741 gagtaacaaa cttacaattg aattagataa ttcgaataat aaaaatactg tcttgacgac
     1801 acctatttat cgttataaag ggcaagtggc ttctattaat ggcaaactag tacaaacaaa
     1861 attatctaag tttggcacaa ctgaattaac tattcctcca ggtataaata aagtcgttat
     1921 tacttatcag tacacaaaac tagcaattgc ttcaagatat ttatctatcg ttactttgat
     1981 tttattttta ctttatcgat ttactttttc taaacaaaaa caaccgagaa gagaagtaca
     2041 acattctcac tagattttta tttaagaaag actttttagc tgtacacata aacaggctaa
     2101 aaagtctttt tttatatttc tttaatttgc ttcatacatt atttaacatc gatatttata
     2161 ctgtgaaaca tgcgtttcat ccattatcaa agtattttta tcgataataa acttcatcca
     2221 aaaacagacc ttgtgcaggg acggtttctc ctgcatgttg ccgcactttg ctttcaaata
     2281 tttcatcgat tgtttctatc ggcatggcac ctgtgccgat ttctagtaat gtccccatga
     2341 taatccgcac cattttatat aagaatccgt ctccgacaaa agtaaaatga agcatttctc
     2401 cctttcgttc gatagataat tcatcaatcg tacgcactgt ggattttttt gattttttca
     2461 atgcagaaaa accaatgaaa tcatgtgtac ccactaattt ttcgcaagct gcattcagct
     2521 tgtccatatc caactcttga gggaaataaa agctgtggtt tcgctcaaat gctgaaggaa
     2581 tcacgttgtt ccaaacataa tagctgtatt ttttgcccac cgcattatat cttgaatgga
     2641 agcgctcagg catttcttcg attcttttga tgacaatatc ccgcggaagg taacgattca
     2701 taaagtcgat catttctgcc agtccaattt ctgtgtttgt tttaaaattt gctacttgtc
     2761 ctcgcgcatg ggtgccagca tctgttcttc ctgatccaat aatttctatc tcttcatttg
     2821 tcatctgatg caatactttt tcgatttttc cttgaatggt tttatcgtca tctccaagtc
     2881 tttgccatcc tgaatatctt tttccgtcat attcgattgt caacttgatg tttctcatat
     2941 tttagtggct cctctgtctt ccatttggtc ttctctctac ctttttaaga ttgtagcaca
     3001 aaatatagct ccttgcttct ctaagacaga agctatacaa gaaaactgtg gaaatatata
     3061 tttcagaaaa acaaaaaaca gccaccggat gaagtatccg ctgactgttc aatttgacgg
     3121 ctcaagtttt actgtttgag atgcaagata ctcaaccagg caatgggcac ataattaaag
     3181 aaaaaactga ttctttggca aaaacctatt ttattcagta atggccaaga atttatagaa
     3241 ggaattcttg ccagtccata aatcgccgca aaaagcaaac tgatcacaga cagtccaagg
     3301 tataagtggc ttacgtccat ttgcccattt tttcgataga tcaagaaaag aagaactgga
     3361 aacaataaaa aaccactgta acctaaacct gatccgatat tatggaccca tgtcgagaca
     3421 ttccacgaag attcatgggt attgatactg aacaaacctg taaagataca atcacctata
     3481 ccatagaacg cgatggctgc tgtaactagg gtagctaaca cacgagatgt actaacaaat
     3541 gcagcataca atgcaggcaa tgacaggatg aaaaagatcc ctgaaaccac agaccaaata
     3601 agaaacgctt ttcttacagg actggaaacc tctccaaata cactgatcac gctcttcatt
     3661 tgatctaatt caggataata caatcctaat acgtacggag tcaaaaaatc actcagcacg
     3721 cctaataata aaaagaaaaa accaaattta cgtaaaaaat ccatgatacg cctccaataa
     3781 caattaccta tgcttttaat tgttattata aacgacttta tcttgattta acagaaacct
     3841 ctatttacac gaacatctat ataactcatt aaaaactcga atcattttaa aaatactaaa
     3901 tatctaacgt tcaacgttca cttaatccat ctaaacaatc tttcaatttg attttttccc
     3961 cacttctttt acgcgcgcct agctctccta ttgcagtaaa caacagatca cttgacgaat
     4021 ttaaggcagt ttccattgaa tcctggataa caccgataat aaatccaata ccgacgattt
     4081 gcatcgcgac atcattagag ataccaaaca aactacatgc taatggaatc aataacagtg
     4141 aaccgcccgc aacacctgaa gctccacaag cagctaaagc agacaaaata cataaaagga
     4201 ctttcaaaac aaaaggtgct tcaatcccta aagaatgtac agcagtcaac gtcatcaagg
     4261 aaatggtaat cgcggcaccg cccatattga tcgtagcacc taacgggatc gatatggaat
     4321 aagactcttt tgtcaatttc aatctttcag ccaacatcat gtttatcggg atatttgcgg
     4381 cagaacttcg ggtaaagaaa gcgggaagtg cgctttcttt caaacaaaag aaaatcaatg
     4441 gatagggatt ttctttaata aacaaaaacg tgaggaatgg gtacacaact aatgcgacaa
     4501 acagcatcgt accgatcaaa acaagtaaaa gctgcagata ctctgccaat ccagcgattc
     4561 cagtcgtagc aattgattga taaaccaatc ctaaaatccc tatcggagca aatgcaataa
     4621 tcacttgtac gacttgtgac aacgctatag atatctgatc caccaactct tttgtcgatt
     4681 ctgaacgtgc tcgaaaagct agtcccaaca atacagccca gaataagacg ccaaggtaat
     4741 tcgcatcaat aagagattga acaggatttt gtgtgacatt cgtcaacata gtagataaaa
     4801 cactttccaa actttgcggt gctttttcag atactgtttc ttgtaaagta ataggaacag
     4861 taaaaattga acttacaata actgctacaa gtgcagaaag caatgttccc actaaatata
     4921 agatcaaaat aggcttcacg aatgtcttat tcccaatttt atgcttggca attgacgcca
     4981 tcgtcaagaa aaaaaccaga ataggtgcga ttgccttcaa gcaactgaca aacaacgttc
     5041 ccaatattga aataaatgtc catgtgggga aaaagatacc aaacaatatt ccgactaaaa
     5101 taccaacaac aatacgttga actaacgaca tatccaaaaa cttctctaac aaatgaccac
     5161 cctttcacaa ttttaacaat cattgtatca ttttatgcaa agaaactaaa ggtataattt
     5221 tctaaaaatt ctaacaatac aaacaaccat ttcttgctaa ttttgtactt tttctgtcta
     5281 cacgttgttt tttgagatat tctaagttag gatgttatta atgggcaact tatcaggaaa
     5341 cgttttctta tgtttttgtc caattttttt gtgaggtgtt tattcttgaa aaaaataaag
     5401 aaggagagtt atggcttcct gacaatcttt gtcgcttgta taatgatggt tttacagcgt
     5461 atattgattt cagcagtcac tattcctaca tatgcaacaa accctggtcg attctacatc
     5521 tatacatttt tacaaacttc cgttgttatt ggtgcaaatt tgatcccact ttacatgggt
     5581 taccaatatc aaaaaatcgc ccgtttaaaa gttttacatt atttaagtcg ttttgccttt
     5641 atattcctaa tagccacact agtttgcaat atcttttttt acgtacaagc tggcagcttg
     5701 aatattcgtg attattggct tatcctaaca cctatcagtc agaattactt tacttatgct
     5761 gtttcttgta ctttgctttt ttgtagtatt ccttatacag ttggattttt aaataaatta
     5821 tcgaaaacaa caattaaata tctactatta tttttaacaa ttggattagt tggctgctct
     5881 actctattta ataaagaccc gtttgcatta cagaatggac agagtatttt atggattttt
     5941 tatttatttt taatgggtta tggtttgaaa gaatggaact ggaaagaaaa ggtccgctat
     6001 aagcttcctc aagtatttat cagcttgatt gttttattcg gtttgattat tttgatgaca
     6061 caaatttcac tcatcatcag aggaaataca gatacagcgc tgaggttttc taaaccatat
     6121 tctctcttcg caatgtatta tactttctct tcgtttttat ttttagaaat gctatctgat
     6181 aaattaggta taaaaggaag aggaaatttt cttgctgtat ttttgattgt cactcaagtt
     6241 atatgtaatt tccctttagt ttcttatcgc gtatctacat ttatgaaacg tgaatttcca
     6301 aactcaggga aggcatggct gataaatatc gggcagtttt ttatttgata tttattagca
     6361 gtgtccctcc tagttatctt tttattttat atacaaaaaa tccgtttcat tcatcgtttc
     6421 atcgaatact tcgcttttga ttcgattgaa caattaactc agcgttggaa aaaaagaatt
     6481 cattggcttt ttgttcataa aagttatttt ttagttgcag cattttttta ctgctttacc
     6541 ttcgtgcaga ttttcgtttt agaaccaaaa gaaggttgga aagaaactat ccaggttgcc
     6601 ttaaaaatat ttactcagcg acaagcaccc atgatcctga caatcatcat tattatggga
     6661 tttttcttct tactattgtt gatttccaat cgtttttggt acgccttgac tgctaccttg
     6721 atcattaact tactgctcac tatttcgaca gtaatcaaaa tggaaatgcg ggaagagcct
     6781 gtctttcctt cagatttaaa aatgctgacc ggattgtcag aactattatc gatggttagc
     6841 ccagtcttat taatcgtggg cggattgatc cttctcctat tattgattac tagtattatt
     6901 gtacaacgta gactacaaaa acagtattcc ttgaagattc attggaaacg tcgatttatc
     6961 agtatcgctg tattattagg atgtttttcg ggtgtctttt tcattaatca caaaaattcg
     7021 ccttctttct tgctgtttaa tttatttaaa gtaaacaaga ctttctttaa ccagcaaggc
     7081 gccgtaaaag ataacggacc agtcattcaa ttcctaaaca atatcgacat taaaatcatg
     7141 gaagaacctg ctggctattc gaaagaaaaa attaatggaa taatgaaaaa gtacaacaca
     7201 aaggcagatg aaatcaacca aacaagaagt gactggttaa acaatcagac gatcgttctc
     7261 aatttaagtg aaagcttcag tgatcctgca cgtgtcccta atctgacagt acctacagac
     7321 cctattcctt acatcaaaag cattataaca gaaggaacag gaggattgat gttatccgtc
     7381 ggttatggtg gcggaacagc taacatggaa tgggaaggac tgacaggctt gagtatcagt
     7441 aacctgtctg cttcgttagt tacaccttat acccagctag tggagcgtca gaaaataagt
     7501 ccaaatatta ccgatctatt cgatgaaaaa atagccatcc atccttttac agctgctctt
     7561 tatcgcagaa aacaagtgtt tgataaattt ggttttgaca ggttctatta tttagacagt
     7621 ccggataaat taacttatac ggataaaata gaacaaagcc cacgcatatc ggatgattca
     7681 gcatacaaag aaaccttgaa agctttacaa agcaatacgg aaacgtcaca attcatccaa
     7741 ttatccacta tgcaaaacca tatgccttat gatgattact atagtgaatt gaactacact
     7801 gctgaaggaa ctgctgtcat tcctaataga agaaaagaat tacaaactta tatgcaaggc
     7861 cttcactata ccgatacagc agtaaaaaaa ttcatccaag aaatcgacaa aatcgataaa
     7921 ccgattacct ttgtttttta tggtgaccat ttacccgcaa tctatagtgg gaatgattcg
     7981 aaaaaatatg gattagaaca gcaccagaca gattatttca tttataacaa caagtatagt
     8041 cgtgaacaag cagctacgtt aaataaagaa gttgttgctc ctaataactt tggtgctatg
     8101 gctcttgagc atgcgaatat caaagtaact ccttactatg cgttgttgac agaagtatct
     8161 aatcatctac ctgcattaac aattgatcct acagaaagct tgtctaatcg ttttaatgga
     8221 aaacaggtct ttgttacaga ggatagtcaa attatccaag aaaaaaattt aactgagaaa
     8281 caaaaagaaa ttctagaaga ttatcgtctg atacaatatg atcttgttgc aggtaaccag
     8341 tacagtgcaa catgggcgac acaaaaaata aaagactaac aaataaactg agcaaggggt
     8401 tgtgataaaa gacatgtcac aaccccttgt ttatctcatt aatttgcttg tccataaacg
     8461 atttgattaa agccattttt caattcatta ttcgctgtct cgttgaagta aagataatta
     8521 tcgggattcc cctgattttg ttgtgtcacc aatacttttg gctgattttg ctgaaacccg
     8581 aatagataga cgtgcttttt cagatatggt tctgtctctg catcggaata gacggctgtg
     8641 atttgatagt ctgcttgacc tgtcccactt tctgaccatt ctgcagaaac aggcactcca
     8701 ccaatagcca tcttccactc cccgttcaaa atagcttgag ggactttaag accatataag
     8761 tccacactca tttgattcgt ataacttttg tattgttgtc ccattgtttg gccccatttg
     8821 gtcataaatg cctctaattg tgcggatttg tctgcattcc acagtgtttg ttcaacttgt
     8881 tcgctgcttt ctgaagagga agatgaagcc tctacagaag aacttgaagt agatgtttga
     8941 gttgtttcag tcgttttgga agactctgac gaagtagagg tatctgctgt ttctgtactt
     9001 gctgcagttg acttgctctc tgtgctagtt gttgtagtag ttgcaactgt tgctttcgct
     9061 gtttcttttg ttgattcttt tttcgattca ttcccgttgg tacaaccagc taacaaaaaa
     9121 gctagaccaa ttgttactaa aatccttttt ttcaattaaa aaactccttt cgattactcc
     9181 cacttcttta ttctatcaaa taagcaatgt gattttattg atttttcgta ttttctcatc
     9241 aatctttcaa atcttctaaa aactgagaag cacccgctga tgttgtctgt aatacatcag
     9301 cgggtgcttc ttttatttta atcttcgtga ttttccaatt tacctcacgc tttatatttg
     9361 tatttgaaga aacatagact tttagtcatc atcgtcttcc tcatccaaat cttgtcggac
     9421 agtttttcct tggagtcttt gtacttggta gatgatttct ttattgaaac ttaaaagttc
     9481 aacaagcaat tgttgcaagc catatttttc ttctttttca gctaatttga ttgcccgtgt
     9541 gataaagaca ttttggaaat caaaatcttt tgcaaagttt tccaacattg ttgaggctgg
     9601 taaatatttg ttttgaccat gttcgtaaat ttttccataa cgcatgactt cttctaaagt
     9661 agacggaacg atttcatttt caatcactaa ctcatgagag attttattga accatctcgc
     9721 ttcttgatca gcatattctg aaaaaagggt acttaattct tgcgaagatg tacccaaaac
     9781 atacaattgt gcttggatca atttcatttc ttctaattta aaatttgcta atacatgccc
     9841 caccatggcg ccagcagttg gtttatgatg gtcgatatct gcttgttttg tttcttgaac
     9901 aaatttttct tccactatat tcattgattt acgcctcttt tacttttgct gattggactt
     9961 cataacctaa tttttccaca actgcagcta attgttcagg gtggacttca tctggatcaa
    10021 agtttgcttt gattttgctc gcattaaaca aaactttcgt attgcttacc ccaggctgtt
    10081 gagaaaccgc atgttcgatt ttttgcatac agcttggaca agctagtgta tctaattgca
    10141 taataatttt tttcatcgta gttcttcctt cctttttctt gatagtctta ttctagatta
    10201 cagcttccat aaaaaaattg attcttatca agttttacga tttttcttct ttgctttcgt
    10261 gtccaaaata caataaacgc atcgcgttaa agataacgat caagatacta gcttcgtgaa
    10321 cgaacatccc actagccatg taaataaacc cggcaaataa gccgttgagt aaaaataaga
    10381 cgacaccaat ggcaatcact acattttcac gggtatttaa aacagttttc ttagccaagc
    10441 ggtaggcatg aaccaacgat tcaaaattag attgcatcaa gacaacgtca ctcgtttcga
    10501 tagcaacatc cgttcctgat cccatagcaa tcccgatatc agccgcagcc aaagagggag
    10561 aatcattgat tccatctcca ataaaagcaa cgcgcaatcc ttgttcttgg tattttttca
    10621 caaattgaac cttttcgtct ggtaataatt cagcatggac ttcatcaatg cctaacatat
    10681 cagctacata atcagcagtc atctgattat cacctgtcag catcactaac tgttttgctc
    10741 ctgcttgttt caacttagct aattgttcag cgacttctgg tcgaatcaca tctgacacac
    10801 ctatgatttg agtgattttt ttgtcgattg ctacaataat gaccgagctg cctgtttgtt
    10861 gtaattgatg taaatcttgt acttgctttg gtgtgagaga aagtttgtga gcggcaatca
    10921 atttggtgtt gcccgcacaa actgtatgac catcaatctc agctgtgatt ccttgtccct
    10981 tgattgtctg attatctttg actgctaatt gttgaaaatc aatgtctttc tcctgagcat
    11041 aatggatcac ggcgcgcccc agaggatgat cggataacgt ttctaatcga gccactaaag
    11101 ctaagctgtc cccttcatcc tctgtatagt tcttgatagt ggatacagca gtagttcctt
    11161 tggtcaatgt accagtttta tcaaagacaa aagtatcgat tttggaaaaa gtatccattg
    11221 cttcaccgcc tttgactaag atgccccgtt tcgctccatt accgattcct gctacattcg
    11281 aaacaggcgc accaatgact aaagcgccag gacaaccaag aaccaaaaca gtgattgcta
    11341 aacgaaaatc acgactaatc agaccaacaa ccaacgcaat aagtaaaacg gttggagtat
    11401 aatactgaga aaatcgatca atgaattttt ccgcatggga tttggtatct tgtgcttctt
    11461 ctactaattc gataattttg gcaaaggtcg tatcatctcc gaccttagtt gcttcaatcg
    11521 tcacgtagcc atctgctaaa atcgttccag agaagacttc atctccactg attttgacga
    11581 cttgtcgtga ttcaccagtc actgcggctt catccgcata ccctttcccg tcaatgactc
    11641 gtccgtccac aggaatagct ccaccagttt ttactaagac gatatcgcct tcttccacgt
    11701 catcgatttc cacttcttca gtcgttccat cttcttggac aacactagca gtagatgggg
    11761 ccatctcggt caaagccttg attgactccc gcgttttggt caatgttttt tgttccagat
    11821 agctaccaaa caaaaacaag aatgtaacga tagctgactc cttgtattct ccgatcataa
    11881 aggcaccaag cacagcaata gtaacgagta aatcaattga gataactttg actttcactg
    11941 cctgatacgc atggatcata ataggtatga ccgcaataat agaagctatg gctagagcaa
    12001 tgttatagaa caagacaaaa ccagtaaatt ttccgataaa accaaaaata atcaacacag
    12061 ctgataaggc ggtgatatga tttcgatgct cttggatcca cttttgtaat ttcatctttc
    12121 tccctctttt cctttcattc ttacgagact aagtatagat acttatccat cataaaaaat
    12181 tgaccactat caagtttagt caaaaaggcg gttttctttt ggtagaatac actacaaaaa
    12241 atagttagca agaagactca ctaaaagtga tcttgccaac tattgtcgtt tctatcgaaa
    12301 ttttcattga atgattttcc tgtacagcat acatcggaga tctatttctt tatctaagat
    12361 ttttatcttg ctaatttttt cctttagtct ttcaaatcca cgtcgttcat agaattgata
    12421 cgtacagcca ctatctgtaa aaaggaatat ttcttttcct ttctctcttt tttcaaattc
    12481 tgttagcaac ttggtaccga tgccttttgt tttcaaatca ggatttgcag ctaaaaaaat
    12541 gatctctcca tctggcgaat gcttctttaa atatgctgca agcatttgtt catttgctgt
    12601 ctcgtaagct cctttacttt ctttagcaaa tatattttgt aaaaaatcga atatcttaac
    12661 atatatttgc tgtccaaaag aacgatgttt ctttttttct ccttttatct ccgccagcaa
    12721 aacacctgcc aactcgtcct ctgcatacaa agcaagaatt tgagttgctc gattcaactc
    12781 catatacaaa aaatatcttc cgtaaagatt cagcagaagt tcattttcca tatatctctc
    12841 aaagttcatt ccttcaacag caaaatagat agcttttttg taatctttct tttctaaggg
    12901 tttaaaagtt agtttcatca tttcgcctcc tcaacttcaa tgattgtgtt atacttacat
    12961 tataatagac acagtgtcta ctatctataa tcaatcatct ataagtttgt cgattaagcg
    13021 acagctttgc tttgatatgt cggataagga gataggtaaa tgaaaaagac agatagacgc
    13081 gtcaaaaaaa cagaaaaagc tttggctgaa acactatcca cattattagt aaataaaaag
    13141 attcaagcaa tcactatacg cgaactaaca gaaacggcag atgtacatcg ttcgactttt
    13201 tatacacatt ataaggatat ctatgatcta tatgatcaat tagaaagcaa cttttttcgg
    13261 gatctaaatg aaattctctc ttatgatcca gcccatagct atgaggaact atacactcgc
    13321 ttgattgact atgtttacgc aaatactttt ttatatcgct tatttatcct caaccatggt
    13381 gatatttcgt ttcagaagaa agttaaacaa gttattgaag aaaactatct gaacatatgg
    13441 ctatatgaag acaagaaaac gattatcaca gaagaaatga gattctttac tacgtaccac
    13501 gtccaaggtt gtctatccgt tctcaatcgg tgggtagaaa gcaattacaa gtactccaaa
    13561 aaagaattat tagaactctt acagaaactg aatgatcaca tagagaaaat catgccttga
    13621 ataaaaacat actaagctta gttaagaaga accgtaacct tctcgtataa caactgaatc
    13681 ttatttagcc aaattgttta ctgaagattt tttgagtaaa atttctataa ttcctactta
    13741 ttgaaaagta gtttgtagtg ctgcttctcc ctctctaagt gatatatctt gttgtaccaa
    13801 tcaaattcac ctcatcatta ataaattact tttaggctaa tttattacaa cttataggtt
    13861 gaagctgtaa ccaatttata gtcatattat atttttatca tccagtttat tgaattcttc
    13921 tcgtttacct caattcattt tcaaggggaa tcagctcatc atctaacatt ttacgccatg
    13981 ctcgcttcat ttcttgtggg tatttaaatg gtttcgcttc tggatgtttg gctttatatc
    14041 cttcgtaatc cttactgttg ataattgctt tcatattagg aattggatct tcacctggca
    14101 tatattgcag attagaagca tgtaattttt tctcagaaac aaaccactca ttggaaaaga
    14161 catgaatcaa atcatcactt acttgtgtaa aatagcgacg tttaatgaca aagatatctt
    14221 cattgctatc tagtgtacct tcatttcttt gtgcttaaat tcaaagataa ttttctcaat
    14281 aaagattttt gattccagta agattccttt actcctttta caacatagcg ttgtcctttg
    14341 ttttgaaaca tcttcttccc ctctttgcca ttaaaaatag cccaattctc tataaagaag
    14401 attaagcttc attattataa tataaagttt aaatttggtt tattacttac tttttcttat
    14461 tctctagtaa gctaatattg aaaaaaatgt aatcagatca ttatttttat atgttgtaac
    14521 ttcctgataa gaaaactaat taaaagaaag aggtaactac ataaactaat taaaaaagct
    14581 aacttcatag ttggaggata aatggaagaa acttcaatga ttgtttctcc ttgtgttcct
    14641 tcaatcgaca ctagtcctat tatcaatctc tcttttttgt ccatttactt ttgcgactgt
    14701 tccccaataa tcaaatacag gaagcgttat tttttgtcct ttagattcat gtactgtata
    14761 gactattttc gaatccatca cttgataagg catagtatgc cattccttgc caattcttac
    14821 ttcatgattc tgcaaatgtt ctttgtattg taatgcttcc gtgggtgcat agtcataaag
    14881 tcctccggga aggagtgtcg tgtaacgaat aagattttct tgattcatta ccaagtgatc
    14941 tctctgagtg acaactttat gttcatagtt tgcttttgtt gcagcagata cagccaacag
    15001 taataaaaca attgccgtta tattaactac ttttctttgc ttagctgatg tgctcttcat
    15061 gaaaacgaac gataaaatca acgagccaaa cagtacttga aagcctaaga ttcgccaagg
    15121 aaattgaatc atttgaatgg gtgtattttg taataaagac catggaaaaa atttggtgga
    15181 taagagccaa gagactaccg cactaaggta aatcactttt tctttgcgat taaatccttt
    15241 aaaaaagaag agtggacaga tcaaagaaat aataccaatg attcctaccg taaaggttgt
    15301 caggtcatta ttcatcgcac caatcaaact atccgagaca tttaatgctt ggtgttgtaa
    15361 ggtcgtttta tctggctcat taatcgattg aaccatgatt tgtcggaaca tcggatacca
    15421 aaagtatgct gttaaaagaa tcgtcattcc tactgccttt gacaactcca caatcaaccg
    15481 gatgctttct ttttttcttg tttcacttac tacaaagccg cctaagacta gtaagccaac
    15541 ggctattaca ctcataaaag tggaaagaac atgtgtataa atgagtaagc tcatactgac
    15601 tgctaatgga attgcacatg gctttttctc ataaatcagt gcgtaagcat aatacataac
    15661 tatcggtata accgtaagtg caatcgcttc agcaatagca gaacgatgat aaatatcaat
    15721 cgtacggtac ccataaaatg tatataaaca gctaaatata aaagccgcat cgattctttt
    15781 taaaaatttt agtccataat gaaacatcag catgatagta caaacattca atagccaaac
    15841 atataagata taactaacga ttaaattatt acttatccaa taaaaaatga ctgccggaaa
    15901 aaaggtcaag tagggataaa aataattcac tccgctccca taatgattaa acgtcgtaaa
    15961 attgattgga ccagaaaaaa ttgaagataa ccctttgact ctagcaaaat ggaaggcaat
    16021 atcccccgat gtagaaatag tatgaacatt tctaaaataa ttgattgaat aaagtccagc
    16081 aataattgct aggagaatgg acaatattat ttttttcttt acttgcatta cttaattata
    16141 tactcctttc atggattgct ttatctagta taacttaaat tttaaataaa tcgttattta
    16201 tttttactct cacttaaaaa agcactaaaa ttataagaga gggaggtaat ggtctgaaca
    16261 ccaagaattg ttccaacatc gaattgctta actaatgagt tcaaagctta attatgtggc
    16321 tcttatattt accgagcgtg gattgcgatc tctttagcga aacaaacatc tttcataaaa
    16381 aaaacagcca tatccgcttt cttggatatg actatttact actactttac tatctttcat
    16441 tcttcttgtc tcacttatga taaggcgccc ccgcattgat ccggaaggca cggtagattt
    16501 gctcgacaag gatcagacgc atcaattgat gtggatacgt catttttcca aaagagatct
    16561 gagcattgct tcttttcatg acggcttcgc tgagtcctaa agagccgccg ataacaaaaa
    16621 caaggtggct ttttccttgg atacctaatt ggtcgatttg tttagcaaaa gattcacttg
    16681 taggattttt cccttcaatt gctaaggcat agacgtattc ttgttctttg attttcgcta
    16741 agatccgttc cccttctttt tcttttactt gtctcatttg cgcttcgctt aaattctccg
    16801 gggctttttc gtcaggaact tcgatcaatt cgatttttgc ataggcattc agccgtttga
    16861 catactcatt gataccttgg atcaggtatt tttcttttaa ttttcctact gagataattt
    16921 tgatattcat gttttctctc ctttggtctt catgctcact ttgtttatta taatcaattt
    16981 tttcgtctat atgtttattt tggctatttt tgttaaaaag atttccccaa cagttatgca
    17041 caacatccac aggtttatcc acagaaaaca gtgttatttt accttatttc atcacattca
    17101 ttaggcaaac atacgtttta taagaattta tccactttat acacaggctg tggatatgtt
    17161 ttatccctta tttttccaat cctatccgcg tagttttaca cagtatctgt ggaaaaagaa
    17221 aatcaaatat tttcatctga aaacaatgat ttttcctaaa gtttttcata aaaagttcac
    17281 agtctcaaag tagactaaag tcaacaaata agactatact aacagtagat aaatgaatgt
    17341 aattggagga ggaacacatg gatagaaaaa atgtgacacc aaagatgaaa aaaagtaaaa
    17401 ataatagcct ctggcgtaag ttaggtctgg ggcttgttgg agggatcgtt ggaggactac
    17461 tgacagctgg cattttttat gcagcgatgg gcactggcaa caatagttct actgctacaa
    17521 gcggcaatca gaattctgcc ggtgaaacag ttgtggaaaa tgtcaaagtc aatgtagatt
    17581 ctgatatcac caaagcggta gataaagttc aagacgctgt cgtttctgtt atcaacttac
    17641 aaagtcaaaa ccaatcaagc ggttttggcg gactattcgg gcagcaagaa gaaagtagca
    17701 gctcagatga tagtaatttg gaagcttata gtgaaggaag cggcgtgatc tacaaaaaag
    17761 acgggaatac tgcttatgta gtcacgaata atcacgtagt agatggccag caaggtcttg
    17821 aagtcttgat gaaagacggt acgaaggtaa aagctgaatt agttggaaca gatgcttatt
    17881 cagatttagc ggtgttgaag atcaattcag acaaagtcga aacagttgcc tcttttggtg
    17941 actcaagtgc tctgaaggtt ggtgagcctg cgattgcgat tggttcccca ctaggatctg
    18001 aatatgcaaa ttctgtcact tcaggaatca tttcttcctt gaaccgacaa gtgacaagta
    18061 cgaatgaatc gaacgaaaca gtcaatatca atgcgatcca aacagatgca gcaatcaacc
    18121 ctggaaattc tggtggtcct ttagttaata tcgaaggaca agttatcggt atcaactcaa
    18181 gtaagatcgc aagtacttct gaatctactt ctaatgtaag cgtagaagga atgggatttg
    18241 ctattccaag taacgatgta gtgaatatca tcaatcaact ggaaaaagac ggaaaagtga
    18301 cacgtccagc tctaggtatc acaatggtcg acttatctgc cgtttctact cagcaacaag
    18361 aacaaatctt gaagattcct tcatctgtaa ctaacggtgt catcgtgaca aatgtccaaa
    18421 cagctacacc ggctgaaaaa gctggattga aacaatacga cgtcattact aagatcgatg
    18481 acaaagaagt ttcttctggt gtagaacttc aatctgcttt gtataagaaa aaagtgggag
    18541 attctgtcaa aatcacttac tatgaaggct cgaaagaaaa aacaactact gttgaattga
    18601 cgatcgatca atcggcatta aaacaaaatc aaaatagtga aaattaataa aaaagaggtt
    18661 gtgacaaaga cttgtcacaa cctctttatt ttggaaatgc ttctccgact acggcatcct
    18721 caggcaatac taagattcct ttttttgctg gagcatttgg caaatgcaat tcacgagcgg
    18781 aacagatcat tccatagcta tctacccctc gcaaagttcc tggccagatc atcattccat
    18841 ctggcatcat agctcctggt tttgcaacga caactttttg tccagcttcg atattgggtg
    18901 caccgcaaac gatttgcaat actgtaccat tgtctacttc tgtctcagta atcgataaat
    18961 ggtcagaatc aggatgtggg acgcatgttt ttacgtaccc gacaacgatc ttcggttcat
    19021 gatcagcttc aagctgttct tcgaatcctg cttctttgat caatcgattc aatttcgcta
    19081 attcctcatc tgttaagctt acttggccgt tcccttcgat tgttagatga tcggagatat
    19141 ggaaaaagtt ccaagcaaca acttgacctt gttcatcttt gatccgagca acattccatt
    19201 tgcgttcaac agtgttttct gttcctttat cgtcggctat aataaccatc aaggtgtctc
    19261 cgacgtgtgc tttgttataa gcaaaaatca tgttctttcc tccattatcc tttgctgaga
    19321 tttatcttaa caaaaaattg cattcactgc atgaaatttt tttcatgctt tatttccgaa
    19381 gaagcctctt ctggaacacc atttattcgt aacaagggac tgtgacaaga cttttgtcac
    19441 agtcccttta ctgttttagt taattgatta aaaaggtcgt acaagttcca cttgcttaat
    19501 tacttggctg ttcttcttcg tcagaaacga tcaagacatc acaaggtgaa tgacgtatca
    19561 cgtagctggc tacacttcct gtcataaagc gttcgactgc atttagacct gactgcccaa
    19621 ccatgattag atcgatctca tatttttttg gcaatttgac tgccatggat tcacgaacag
    19681 aaccatatgc aataattcct tctatatttg tgtaatcaac agatttccca tattctttac
    19741 attcttcgat catttccttg gctgtttcag tttgctgatc gactagattt tgatcaatag
    19801 gtgcatagcc cataaagtta taaaattgct gatcgattac gtttgctaca tatactttcc
    19861 cattattacg gcgagccact tctaccgctt ttttgaaagc agcaagtgct tgttcactac
    19921 cgtcgatacc tactaaaata ttcttatatt cttgattcat cttgacccct cctaacagat
    19981 gtcagccttt tgttacactt tctaggaacg attcgatttc ctgttttgtt ttacgatctt
    20041 tattcactag acgacctaat tcttttccgt cttggatcac gacaaaactt gggataccaa
    20101 aaatgttcca ttcagcggct acatctatgt acttgtcacg gtctacttca ataaattgcc
    20161 aatcagaaaa gtcattttca atttcaggca tttgcggttt gataaaacgg cagtctccgc
    20221 accagccggc agtaaagaaa aatacactct ttccagtttc tacgtagcct gctaattctt
    20281 ctaaactatt tgggataatc attctttgtc ctctactttc tgtttatgta tttttcaatt
    20341 aaattataca cctttctttc gaactaacaa acattgatcc tctttttata aaaaaaatct
    20401 ggcaaaaagc aatcttttgc cagattttat agtttcacta tcgcattatt ttccgtatac
    20461 gatcgtattt actgttgatt tatccaaacc tttcagtgtt tgaatcaaca tttctcgtgc
    20521 agcttcaaaa tcgcgaatac tgaacatcgt ttgatgcgta tggatataac gtcccactac
    20581 gccaatcact gtacttggga ttccttcgtt ttgtgtatga gcagcacctg catctgtacc
    20641 gccttttgaa acaaagtatt gataagggat attgtttgtt tcagcgatat ccagcaagta
    20701 ctcgcgcaaa cgaggaagca tgatcaaacc tggatcttgg atacgcatca atgtaccttc
    20761 tcctaaatgt ccgaatgtgc catttttcgt cactgtatca tctgctgcag agcagtctac
    20821 tgcaaagaac agatctggct tgaatttatt gacagaagct ttagaaccac gcaagcctac
    20881 ttcttcctgg acattcgcgc ctgcaatcaa tgtatgacct aatgtttcat tttgcaacgc
    20941 ttctaaagct tctaatacca ttgtacagcc atagcggttg tcccatgatt tactgataat
    21001 attctttccg ttggctgttt tgatcgtttc agcgtaagga acgattgtgt ctcctggaag
    21061 gacaccgtaa ctcattgcct cttctcttga ttcaaaccca gcatcgaaca aaatatcggt
    21121 tacttctact gatttttgtc cgcttgttcc tcgcaataaa tgtgggggaa cggaagaaga
    21181 aatacatgga taattcttac cagtagaggt tttaagtgta aaacgctgag cagaaacaac
    21241 gtaaggattc cagccgccta gaggtacgac tttaaaaagc ccgttttctt ggatttgtgt
    21301 cagcatgaat ccgacttcat ccatatgtgc tgcgaccatt acacggggtg catccgcttc
    21361 ttcatgatgg cgcagaccaa aaatgccgcc caaaccatct aactgtaact catctaccag
    21421 cggttccata tgactttcca tataagcgcg aacatcttgt tcaaaaccgc ttgttccttg
    21481 taattctgtt aactctttga ttcgttgaaa tgttttttct tccatatgct attcgtctaa
    21541 atttcagact aaactcctct cagacttata ttgatctgcg gataaaatat gattttttct
    21601 gcagaccgat cgtatttatt atagcttatt ttttctggta gcggttattt atttcaaaga
    21661 aaatatgaga gtgtggtaaa ataagcacaa ggagtaacaa gtgagaagaa ggaggtatgt
    21721 ccacatgtat gaagaaagcg aactaagcta ttttaaaggc gggttagcag ttggaatcgg
    21781 tctaggatta ttgagcgggg tagcttcaac gatttggtat catcgcaaaa aagtattgtc
    21841 agcagaccaa gtacttgaaa atatcaagtc atcttttcta aaagaaggtg caatcgaagg
    21901 ttcttggatc tcttttgaaa aggaacctat taggaaattc gccgttcggt cgagtgctta
    21961 tcggggaggt ctttctcgaa tagaagatgg cgaaactgtt tattatgaat ttttagcaga
    22021 tgctcataca ggaaccgtat tagaaatttc aagaaaaaaa ggtgcaacag attaatacgt
    22081 caaaaaagtg agagaacgaa tacgcaccca ctattcaaaa gagaggtatc atgtccttct
    22141 tttgtagtgg gtggtttttt agatagagct ttccaaacat atattccagt attttctttt
    22201 taaataaatg atatttagcg ggaaaaacta gcatttcctt tgattatgag gtatttttaa
    22261 tttagctttt gttttctata gttaaggaga gtgaaaaatg gaacaacaag aaaaaattgc
    22321 tgttctgatt ccttgttaca atgaggaagc aacaatttca acagtcattg cagactttaa
    22381 acgagaatta ccagaagcag atatttatgt ctatgataat aattcgaccg atcgaacata
    22441 cgaattggcc gttcaaggtg gagcaatcgt aaaaaaagaa cctcgtcaag gaaaaggaaa
    22501 tgtgatccgc caaatgttct ttgatatcga tgccgactat tatttaatgg tagatggcga
    22561 tgatacttat cctgcagaag ctgtacatgg tttgctcgag aaattacgtt ctggtgaagc
    22621 agatatggtc attggtgatc gcctatcaaa tggaacctac tttgatgaga ataagagacc
    22681 tttccacgat tttggaaata accttgttag aaatacaatt actagaatgt ataaaacaaa
    22741 aattcttgat gtcatgaccg gctatcgagg attcaatcgt atctttgtca aaagttttcc
    22801 tattatgagt tctggttttc aaatcgaaac ggaattgacg atccatgctt tagataaaaa
    22861 attcaagttc gttgaaatcc caatcgatta tcgtgatcgt cctgaaggca gcgaatcaaa
    22921 attgaataca ttctctgacg gattcaaagt gatcatgatg attattaaaa tgtttaaaga
    22981 ttataagcct ttgcttttct ttgggatttg gaccattttc ttctttttat ttggattggt
    23041 cacggggatt cctgtgattc gcgaatatat gctgacaagc tttattacac gcatcccttc
    23101 tgcgatttta agtactggat tgatgacttt agcacttctt tcattagtaa cagggttgat
    23161 tttggataca gtcgtcacga acgctaagaa agaatatgaa ttgaatctat atcatgttta
    23221 tcatgaatac cacagtagaa agtaaaaaaa ggatcaagac tgcaaaaata atttgcaatt
    23281 cttgatcctc tttttaatta attatttcgc caaacgatag atggcatctg catagattgc
    23341 tgttgctctg aacaagtcat caagactcat aaattcgttt gcttgatgca ttgtatcagt
    23401 atatcctggg aacatcgctc cataagcaac gccacgtttc aacaaacgtc cgtaagttcc
    23461 gccaccgatg atttgttcgt agcctttttc tccagtgtgg tcttcataga cttgcaataa
    23521 tgtagccacc aatggatcat ccattggtac gtaatgtggt tccattacgc gagcacctcg
    23581 agtaactgtt gcgccttctt gccccactgt ttgttcgatg tcactttgca atccgtctac
    23641 tgttacacct tttggaaaac ggaaattcat attgatgaag ttcgcttcct ctgtaccatt
    23701 ttcttcaaaa gcaaatagtc cagcattcat tgtcaatttg cccatttttt catcttcata
    23761 agcgactcct agtttttctc cataaaaatc ttcatggaca taagcagctg ctacatggat
    23821 aaattgttta gcagatccta ggaattcata gttatctaag aacaatgcca agaaagaacc
    23881 tgcattgata ccagattgtg ggcttgcacc atgtgcgcct ttaccaacta attcgatttt
    23941 tacatacgta ttgtccgctt caatcgttcc gcttactgga tttgcttcga tgaattggta
    24001 aaatgcttct tccatcgcga tagctgcatc tgcacttggt acttgaagtg ctgcagttgc
    24061 tgttcctggc accatatttt cgcgaagtcc ggaaacaaaa gatttcaaga cataatctcc
    24121 tgcattgtcg cctttgaagc gtaaagctaa agaaacattt cctttttcac cattgatgat
    24181 tgggaattca gcatctggtg agaaaccaaa atctggttct tcttcatgtt cgaaataata
    24241 agccatatcg ccccagccgc tttcttcatc gctgccgact acgaagcgaa ctttttttga
    24301 tagtttcaag tcaagttctt taatgatctt catcgcatag taagctgcca tacttggacc
    24361 tttgtcatcg cttgatccgc gtgcaaagat ctttccatcc ttgattactg gttcataagg
    24421 atctgtgtcc cagccatctc ctgcaggaac gacatccatg tgtccaaata tccctagcgt
    24481 ttcgtctcct tcgccaagat caatatgccc tgcatagtta tcgacatttt ttactttaaa
    24541 tccatcacgt tcgccataag ctaacatatg tttcaatgcg tcgcgaggtc caggtccaaa
    24601 tggtgcatct ggtgttactt ttgagtcatc gcgctcgctg ttgacacgta aaagattttt
    24661 caagtcttca agcaagtctt ctttacgtgc ttctacttct ttttgccaat caattgtcat
    24721 aaagttaatc ctccacttat ttaagtcttc gtgttcatga taccacaaat tacagaaaaa
    24781 aatagttcaa aaaatctgac aattcctttt cttatctgtt tttctctaaa aaaaatatac
    24841 gctataatga gtaaaaggag gtttttagat gctgataaac gaacaactag tgaaaagagt
    24901 catcacacct cgtccaaaaa tttcacataa aggaacattt ggacgtatcg ttttgattgg
    24961 cggcaatgaa caatatggcg gagcaatcat tatgagtgct ttagctgccg tacacagcgg
    25021 agcgggtctc acgactgtag taactgatga aaaaaatcgg agtgctcttc acagtcatct
    25081 gccagaagca atgattgtag tttggacgga tactgaccag tttctttccg taataaagca
    25141 agcagatgta ctcttgattg gtcccggatt gggtacttct tctaagagtt tggaacgttt
    25201 caaacaagta ctagaaaacc aatcaaaaga acaatggctg gtgattgatg gctctgcttt
    25261 aagtttactt gctgctaatc atcttttgct accctatccc gaacaaactg tacttacacc
    25321 tcatcaaatg gagtggcaac ggttgagttc tctaccgata caagaacaac gggataaaga
    25381 aaacaaaaag aagcaacagg aaatcggtgc tgtgctcgtt ttgaaaagtc atgagacaaa
    25441 aatttatggt caccagcact tctacaccaa tcctttaggt tctgctgcta tggcaacggg
    25501 cggcatgggt gacactttag ctgggatgat cacaggattt ttagcccagt ttcctcaaaa
    25561 tgaccaaacg attgcagcag ctatttatct tcatagtttc attggagacc agctggcaaa
    25621 agaacaatat attgttttgc cgacacaaat cagcgaagca cttccgaaat ggatgaatta
    25681 tttttgtaaa aaatcaatgg aaaacgaggc atgagtcatg gagaaattta caggttatgt
    25741 gcgagaacct ttttattatg aaacagatca aatggggatt attcatcaca gcaattatat
    25801 ccgctggttt gaagaggctc gggtagcctt attggtacat ctagggtttc cctataaaaa
    25861 aatcgaagaa tctgggatca tcatccccgt tctggaagta aattgcagct ataaagaaat
    25921 gatccattac ggagaaaaag tgagcatcca tccaactatc caaaagtata cggggacacg
    25981 gttggatttt agctacgaaa ttgtgggaac tgaagacaaa aaattaaaaa ctactggcag
    26041 tagtaaacac tgttttttac tttctgattc gcaacgatta gtgaagctga gcaaagtcaa
    26101 tccggagtta gatcagttat tccaagcgta cgcttctttg gatgatgtaa attcttaata
    26161 aagaccgtct aagcattttt cttgtattgt gtcgagtagt tcgtataatg aaaagaaaaa
    26221 agcaggtgat ccccatgtat gtcgttaaag taatgcacgg ttacatcgat aaaactggct
    26281 gtcgcactcg ggaaaaaaac ttagacaatc tgctcatttt caaagacaaa aaagaatccg
    26341 aagcttttgc taaaagaatc ggcggtcgtg tcaaaccgat ccaagaggta cgaccagatt
    26401 gattcaatat ttttcttttc gaggctctaa taggcatgcc tatcagggct ttttttgcag
    26461 actgtgtttt tatgcccaca cgatttgtaa gcgatttatg ttataataga ttatatctgc
    26521 atagaaagga aggttaaatg gttatcaata atttgcaaca gcaagcttat gaatctatac
    26581 gtaaacaaat catttattcc gagttagcac ctggaagtaa aatctccgat aaagtgttag
    26641 aagaacaact agctatcggg cgtacaccga ttcgagaagc actgatccaa ctgcgcaatc
    26701 aagagcttgt aaaaaccatt ccacagtccg gcacttatgt ttcaaaaatc gatatccgat
    26761 ctgcttcatt agcccgttat acgcgggaaa agttggaaaa accgatcctg caagaatgca
    26821 gtgcgaaaat gaccaagcaa gatcaagcta aactagaaaa aatactagaa caaaccgatc
    26881 aggcagtaat cgctcaaaat aaaaaagctt ttttgatttg gatactgatt ttcaccgaac
    26941 ttgttatgaa attgctggaa aacgagaaat ttgggattgg ctagaaagtt atagtacgca
    27001 cttgaaccgt ttcagatggt tacgtttgac gatttcagaa ttagactggg gtcgagtatt
    27061 agatgaacat cagacaatgc ttcaatcaat gattgatcat aactttgatg aagtcggatt
    27121 tctttgcacg atgcatttac atatgattat cgaggagcaa gaatacgtga ttcataatta
    27181 ccccgattat tttgaagata ttcaggacag acccatcaaa taagaggttt tggaatcagc
    27241 gttttgacct gagtattaga gaaagaaacg gcaaaatagt tcctcatatt ttgccgtttt
    27301 ttttgagcta ataccgaggg tcagctgatt gcacaccgtt tattgagagg ttgtgaaaaa
    27361 gctgccctgc atcaagtaat aagaacagcc aagtaaaaat agcttcttat gtttttaact
    27421 tggctggact tattaccgca gatgcaagct tttgaacacc gttttccaag aggtcgtgag
    27481 cctgccgttc atctccgagt cacaaggaac aatttcaaaa aacagcttct catgtttgtt
    27541 gaatattttg acttgtgacc gaggagttga caggagaaca tcgtttattc ggaaaaaaag
    27601 gactgtgaca cgacttttgt cacagtctct ttatttgtaa tctaaatcat actccgtaca
    27661 tcttttttct atttttttta tttcttctaa gatcccttgg ctacgaattt cattatatgg
    27721 ccaaagtaag actgcctcta atacataagg cgaaaaatcg ctttgattca tctcttttga
    27781 aaaactcatc gctgctatct cgctcaatgc acgaatgttt gattgatgtg tataaaaagg
    27841 caaccgccac agcacaattt tttcgctttg cgtataaatt cccttaacag aagcttcgat
    27901 gtggtgaaat agttcatgtc caataatcaa agcttgcgct gtttctttag agatcgaagc
    27961 tagtcctgaa cattttaatt tttctaacgg ctccgtcatc aatcgaatcc cttcatcttc
    28021 tgcataagtt gcaaaagtga ttcgttcgtt tatttgctct gattcacagg aaacgattgg
    28081 aacagccatt tgttcacaaa tttctcctac atcggcaaaa gggtactttt ttttgatgct
    28141 acatgccgtt tcgataccac aatcgattga ttgttgtata agaattttct gcttggacaa
    28201 aggaatcttt ttccaaaata aatctcgccg aaactggtag aatccccaaa tttcttcggg
    28261 gatctgttgt aattcgttta gtaactcttc taacttatgt ttgtttgata tttccggcaa
    28321 cgacgatcac ttcttcctcc ggttccatag tagatacttc cagatccatc aaaagctgta
    28381 gttgttccag atccgtcgct gtaaaatcag agactcttgc tcctaagcag agataaaatt
    28441 ctggtcgggc aatcaattca gtttgataaa ctgccatatc ttcccaaagt tgttcgacag
    28501 ctgtcatata attggctgca gttgttttca tacatgaagc atgtccacgt tggaccttga
    28561 taaatccttt ttgatcgatg atccgaagac ttccagcatt ttttgaacga ttctgttcgc
    28621 cgcatacata aaagaaaggt gtattttcca ataagcaaac ttcattttta tttaatcgca
    28681 tatcctctgc agcaagctct agtgcttctt ctgttgtgat ctccttggtt agatcggttg
    28741 ctttcacttc cgtagaacca gtagcgatag ccgttacttt tgaagtctgt ggatcgattt
    28801 ctacgtggac ttcgatcgat tctggtgtag cgcctgattc aatcgcttta ttcatcgctt
    28861 catttttcaa cgatcgtata tcttctttac ttggcgaagg gatgatacgt tctacaacat
    28921 ctcggaccat tgcaagtgct acaccaatag aagaaatcac ttcggcgttt tcaggaatcg
    28981 aatatttcac acccatttta ttactaaagt aagtaatcaa tgaggcagcg ccgcccccta
    29041 cacctacaag agaaatctga tctttctcca agtgatactt gtctgccaat tctaaaatca
    29101 ccggttcaat cttagcatag gatttttcca tgatctgttc tgcgatgtct tcaaccgtcg
    29161 tatgacaata atcagctaat gcttggatgg cttttcgtgc agatgggaca tttccataag
    29221 aaaaatgttc ttcttgcact aatccaagga cattggctgc acatgtattt gtaatagtca
    29281 cttcttctcc gtcttccatc actaccttga cgtaatcagc agggtctcct tctttaggag
    29341 agaaaaattc aaccttagga cctttgattt tttctgtctc cgtaaatact gcataatcta
    29401 gaccggcaat atgtgcagaa cgtggaccga catcgatgat tcctgactga ttagcccgta
    29461 ccatcgaacc gcctgccaca cctagaaccc gaacatctaa tgaagagata tatgttgggt
    29521 ggccggtggc cacctacaat tgaataatcg attgctggac gtccattttt aatgaccccg
    29581 atattggttg ttgttccgcc tacttcaaaa taaacaccat tagacgctct caagtacatc
    29641 aaagagccca tgactgatgc tgctggaccg gaaagcatgg ttaaaacagg tcgttttttc
    29701 atttcattga tttccattac tccgccgtct ccgcgcataa tcatcaaaga aacattgacc
    29761 cctgcttctc gtacggaatc ttctgtagag gttgccgtat ctagcatttt tggtaaaata
    29821 gatgcattga ttgctgctgt ccgagttctt cttgtcaatc catataattt tgtgatgtca
    29881 gaagccatcg ttgtagggat cgattttacc gatgctgctt cataaacaac tcgttctggt
    29941 tccccattat ctactccaaa tgccatagaa gaaaccaaga cctccgctct ttctctttct
    30001 aaagaagaaa tcgtttctga aacacggtct acatttaagt gtttgacagg taagaatgca
    30061 ttgacaatct ctattttttt cttattccct aaatcgatat cgttcaatct agtttgtcgt
    30121 tttgctaaaa aaccttctaa tccacctttt gccatcccga ttacgccgac ttttgctacg
    30181 tctccttcaa tcagtgcatt agtcgcttgt gtggtagaat gtgcaacaaa cacaacatct
    30241 tctggactga tattattttc cagcaaacaa ttttgaaaag actgaacgac acctgcggct
    30301 actccacgga catcatcgtg ggttgttttc actgaagatt ttccgatgat ttcgtgcgtc
    30361 gcattatcga ttgcgactgc tttcgtatgt gtaccgccaa catcaattcc cattcgcaca
    30421 aaacgtttca ttttcttttc ctccattcat ctaatcgttt ttatcgacgt tttgtttact
    30481 aggcgttccc gtacaataag aacgtgatca ggcataagat cgctccgatg atccaaccag
    30541 ttgggatgga tttcttcata tattctcgag aagttacttt tgtataacct aatccccaag
    30601 caacccaaga ttgtgtaata tctaaatgct gaggagcaat cgttgtgatt gcaaataacg
    30661 ggaacaaaaa ggctggcgac atcgttggat taacagctaa tacgacagct aaaatagctg
    30721 agcctgaacc gactagattc attggaccgc ggaaaaatcc tagtggtgtc aatatagcaa
    30781 atacgattgc caagactaat ggtgattgcg gtatccaatc tccaaaaata gctgaaaaat
    30841 aaggagaagc atacgcagct gaattattga acatcgctaa ggtcatcaag aaaccaacca
    30901 ttggcgcaac atctactgcg ccatctgtaa ataatttcgc aaactgacga cagatttctt
    30961 tataacctcc gcgcaatttt ccagtaaaca gcaatgccca gatacctgct agaataaaac
    31021 ctaagatgat tggaagatct aaaagaacga cccctaaaac tggtaataat acggctaacc
    31081 atgagatcat tggtgcgtcg ccaccttcag ctggtacgtt tgctgccatt gcatagcgtt
    31141 tctttttgtt cattgatata ttagcgaccg ttagtaccac aactaagctt acaatcatcc
    31201 caatcatacc aatttggaaa tagtcattat aagtatagct ttcagccgct ggattgaaac
    31261 cagcataaat cgtttgatat tgtttgaaat tgacgatatt agcaaagatt ccagccataa
    31321 tcgagcccat aaatgagaac agtgcaaccg gtactgaaat acctaatgac atcaagattg
    31381 gcaacacaat aactgcaata gaaatcactg gtccgattcc tgtcatcgac atgaatataa
    31441 cagcggttac aatacatagt aagctcatcg tgattcttgg cttgtcccct ccaagttcaa
    31501 ctacctttcg aatcagggta gctgcgattc cgctatctac tagaacacgc ccgaaaaagg
    31561 caccaaagaa gacatttacc aagatcgatt tggcgtactc agctggcccc gtcgtataga
    31621 tatgcgtcaa cacatcaatt actccttgcc cttccatcgc cgggtttggt gaaaacgtgt
    31681 ttccgactag cgctaatccc atccatacag tagccatgat ggcaaagccg accatcaagt
    31741 tgtagccttt tacacagtac cagaccatga aaaagaatga gataactaac aaaataccaa
    31801 taataatatc actcatgtta ttcctccgtc cattttgttt ttctgataag caaactaata
    31861 tatcagtcaa actcattcta acttatgtag ttagcgcttt cattaaaggg tgaccataaa
    31921 tgttcagttt tcaattaaaa aaccttaatt atgctatttt agacttatac gttattgtcc
    31981 tgtttcattt gatggaggat tgtaaataaa aaaagaggaa agaacataac ttttcgttat
    32041 cttctttcct ctttataatt gtttagctta tttagccaaa gcttcttttg cttggtcagc
    32101 caatgcagta aatgctgctg catcgttaac agccaagtca gctaacattt tacggttgat
    32161 gtcgatttca gcaactttca aaccgtgcat taattttgag tagctcaagc cattcatacg
    32221 agctgctgcg ttgatacgag caatccacaa tttacggaag tcgcgtttct tttgacgacg
    32281 atcgcgatat gcgtagttgt atgaattcat tacttgttct tttgctgttt taaataaagt
    32341 gtgttttgaa ccgtagtaac cttttgctaa ttttagcact cttttacgac gtttacgagt
    32401 tactgttcca cctttaacac gtgccatgta taattcctcc taataaaaat aaatcttcag
    32461 attctgttat ttgtacttct tatttcattt ttgctagttg ttggcgaata cgtttgaagt
    32521 cgccactaga aaccatgctt gctttacgca attgacggcg ttgttttttt gttttgccgt
    32581 ggaaacggtg acttgtaaac gcgcggaagc gtttcaatcc gcctttacca gtacgtttga
    32641 aacgttttgc tgatccgcgg tgtgtttttt gttttggcat gactatattt cctcctcaaa
    32701 atctttcgtt atccgactat cggctgtcca acagccagtt agtcattcaa attacttact
    32761 gtcgtttttc ggtgccagcg tcaagaacat gctgcgtccg tccattttcg ctttttgttc
    32821 cactgttgca atatccgcag tttcttcagc taagcgattc aagacttttt gaccaatttc
    32881 tttatgggta atggcacggc ctttgaaacg gatagaagct ttcactttat cgcccttttc
    32941 caagaactta cgtgcattac gaagttttgt attgaagtca ttcaagtcga tcgtaggact
    33001 taagcgaact tcttttacat tgatcacttt ttgtttttta cgcgcttcgc ggtctttctt
    33061 ttgttgttcg aaacggtatt taccgtagtc catgattcgc gcaactggtg gtttcgcacc
    33121 aggggcaact aacacaagat ccaagtttgc ttgttctgca atattcaatg cttctgcttt
    33181 tgtcttaact cctaattgct caccatctga accgatcaat cgtaactctc gtgcacgaat
    33241 gccgtcgtta accatcatat cctttgctat ggtcattcac ctccaaatat tatgagagaa
    33301 agaaaagctt accgaataaa cggcaataaa aaaacgagtt ctcttacaga acccgcgcgt
    33361 acttcaccta atagaaccag tgaaaactat ctagcccagt gacattatca actaaggcga
    33421 gaagcgggtg cttctgcttt tatttctcaa ccatcatagt atagcaaaaa ctaatctttt
    33481 tgtcaatgtt tttcatacag tttgtcttcc ttttctgaaa atgattagat tagcagactt
    33541 tctagcagtg attcccgctt ctttgtgcta tactaaagaa aaacgaggtg aacccacatg
    33601 aaaaaaatcg aacctattcc accttctctt cctcttctta caaagggaga gttttattta
    33661 gaagatgagg agatcttctc tggtcttctg atcaacgggg gtgaccaaag ctatctcgat
    33721 gccaaaaata tggtattaag agagagtcat atccaaaaac ttacgatgca aaaaacagtt
    33781 ttacgtcatt ttgaatgcag taatgtcatt tttgaaaaat gtgatttttc caatctggag
    33841 tggattggtg gcagtttcca ccaagtcgtg tttcatcaat gtaaattaac aggtacgaat
    33901 tttgccgaaa gttatcttcg agactgtact ttcactgatt gtattgcttc gatggcttcc
    33961 tttagtagta caaacttgaa agctgtctcc ttcgatcatt gtcaattaga agacagcgaa
    34021 ttttatgagg tcacttggaa aaaccttttt ttgtctgaca atcagttgac cggttcgaac
    34081 tggtttcgaa cttctctgaa gggattagac tttacgacta atttcttcac agcaatcgct
    34141 ttatctcaag attctttggc gggactaatc gtcaaccaag agcaagcact tgtgatcgcc
    34201 caagcccttg gtttgcagat caaagactag atcaacgaat ccgccgccac agtgcaataa
    34261 gcatccaaat agataagacc aaactgatga tcaaggcgat tccccatccg aaaacggaat
    34321 gggtaaaggg taactggaga ttcattccga agaatcctgt cacaatagtt ggaacggtca
    34381 agatcagcga ccagaccgtc aaaaatttca tcgtgtcatt caagttgtta ttcagcaaat
    34441 tattataagt gccagagagc tggtctaaaa tctgcgaagc taagttcgtc atttcaactg
    34501 cttgtcgtgc ttcgatcagc gcatcgtcca actcttcttt ttccttttct gacaacttgc
    34561 gataaatagc caatgccttg atttgttcta aaagtactac attttgtttt gttcctgtaa
    34621 ctaagtaaac caaaccgatc tctaaatctg aaagttgcag cagattcttg ttcgttgttt
    34681 tttctcttaa tttcagatta agccgctgac gttcactatt cacttcctcg attaaaggaa
    34741 aaaaggaatc agaaatcaaa aacaatgtac gaaacaataa actgtataca ctcatgtctg
    34801 gcattcgttc caaaagcgat cgaattagtc gaatcacgta ctcggtattc ggcgtggtaa
    34861 atgtaaacaa accgtcttct tttaaaataa aagcgatagg actagtttca taatgattat
    34921 cgactttttg ctggtgcgga acatttgata caagcagtaa cgcttcatca aaagaatcgt
    34981 actctacgcg cgcccgttca tttttatcta gagaataagt cagcatctcg tcactaatgc
    35041 catattcttc ttttaagttt ttaacagcta gcacatcgtt ttgctgtaca ttgatccaaa
    35101 aattacggtc ttgattaaaa tagtgttttt cccgcatact ctatcctcct gacatttgtt
    35161 tccagtataa agaaaaaagt cgctcaaata aaggtttacc ctttatttga gcaactgtaa
    35221 atcaaatggc tactttggtt tggcgaatct ctgctaattt ttcttcgatc attttcaaga
    35281 cttcttcttt tgcttgagga tcttccacaa aattatagcg gtctccatcg atttggattt
    35341 ttggactttc tttgtattct tcataccatt gatcgtaacg tctgttcaat tctttgtaat
    35401 aatcgtatag acttggatca aaggacaatt gttcatacga acgaccacgt ttttcgatac
    35461 gctccaacat cgtatcaaaa gatacacgaa tatgaactaa taaatccgga tgttttttat
    35521 gggcagcata gggaagttct tccatcatgt tttccagcag ttcatcatac acacgaactt
    35581 ctgtttctgt tgctcttcct agatctgcat ttagatggaa aagcagtgaa tcttcataaa
    35641 tcgaacggtc caatacatta ttgtcatctt tcattgcttg tttgatgctt gcaaaacgtt
    35701 tattcaaaaa ataaatttgc agcaaaaaag catactgttc agggtttgca taaaataagg
    35761 gcaagacttc attatcatca atcgattcat aaaatgcctg actatcaaag tgttcagcca
    35821 tcatttctgt taaacttgat tttccggcac caattgtacc tgctaaaacg atcacgctca
    35881 tttacctcca gctcacttca tcactaaata ttgtgtttaa ctccaacctt tttaaatata
    35941 cccccaatat ctagtagtgt caattgtatt tttttctagt caaagaagaa aaaaagtcaa
    36001 aaaattctta agaaaaaagt gttttttctt tagaaaacgt attcttagtt ttacttctga
    36061 gatggtttta gtaaaataaa ggaggaatgt tttttgagac ccttagtgga caaaaaaatt
    36121 cgtgaagcag cgcaactcgt tttgggcgct ttattttttg cttaaaaatc acttttacgt
    36181 gagaaggagt tagattatgg caaactatgg ccaaggagaa tcaagcggaa agatcatatt
    36241 gatgggcgag cacgcggttg tttatggaga accagcgatt gcctttcctt tctatgcaac
    36301 aaaagtcacc gcattccttg aagagctgga tgcaatggac gatcaactgg tttcttccta
    36361 ctattcagga aatttagccg aagctcctca tgcattaaaa aatatcaaaa aattattcat
    36421 tcacttaaaa aaacagcatg acatccaaaa aaacttgcaa ctgaccattg aaagcacgat
    36481 tcctgctgaa cgtggaatgg gatcaagcgc tgcagtcgcc acagcagtca ctcgtgcttt
    36541 ttatgattac ttagcatttc ctttgtctcg tgaaatacta ttagaaaatg tccagctttc
    36601 ggaaaaaatc gcccatggta atcctagtgg aatcgatgca gccgctacta gcagcttgca
    36661 gccgatttat tttacaaaag ggcatccttt cgactacttt tctttgaaca tcgatgcttt
    36721 tttgattgtc gctgatacag gaatcaaagg acaaacaaga gaagccgtca aagatgtcgc
    36781 tcacctcttt gaaacccagc ctcatgaaac tggacaaatg atccaaaaat taggatactt
    36841 gacgaagcaa gcaaaacaag caatcattga aaattcacca gaaacgttgg cacagacaat
    36901 ggatgaatca caatcacttc tggaaaagct gacaatcagc aatgattttc ttaatctatt
    36961 gatccaaaca gcaaaagata ccggggcatt gggtgccaaa ttaactggcg gtggacgcgg
    37021 tggctgtatg attgcattag cacaaacaaa aacaaaagcc caagaaatca gtcaagcact
    37081 tgaagatgcg ggtgctgctg aaacttggat acaaggatta ggagtacata cctatgttta
    37141 aaggcaaagc acgcgcatat accaacattg ctctaatcaa atattggggt aagaaaaatg
    37201 aagaactcat ccttccaatg aacaacagcc tttcgttaac attggatgca ttttatacag
    37261 agacagaagt catcttttct gatagctata tggtagatga attttatcta gatggcacct
    37321 tgcaagacga aaaagcaaca aaaaaagtca gtcagtttct tgaccttttt cgtaaagaag
    37381 ccggcctctc actaaaagct tcagtaatca gtcagaattt cgttcctacc gcagctggat
    37441 tagcctcctc tgccagcggg ctagctgctt tagcaggcgc ttgcaatact gctcttaagc
    37501 ttggattaga tgatctctct ctttcaagat ttgctcgacg cgggtctggt tcagcttgcc
    37561 gaagtatttt cggtggtttc gtcgaatggg aaaaaggcca tgacgactta agttcttacg
    37621 ctaagccagt cccttccgat tctttcgaag acgatttagc aatggttttc gttttgatca
    37681 acgaccagaa aaaagaagtg tccagcagaa atgggatgcg tcggacagtc gaaacatcca
    37741 gtttttatca aggctggtta gattccgttg aaggggatct atatcaattg aaacaagcaa
    37801 tcaaaacaaa agatttccaa cttctcggag aaacgatgga aagaaacgga ctaaaaatgc
    37861 atggaacgac tttagctgcc cagcctccat tcacttactg gtctcctgac agcttaaaag
    37921 cgatggatgc ggtgcgacaa ttgagaaagc aaggcattcc atgctacttt acgatggatg
    37981 ctggccctaa tgtcaaagtt ttagtggaaa acagccattt atctgaggta caagaaacat
    38041 ttaccaaatt atttagcaaa gaacaagtaa ttactgcaca tgctggtcca ggaattgcga
    38101 ttattgaata aagggagatt tttatgattg aagtatctgc accaggcaaa ctctatattg
    38161 ccggagaata tgcagttgtt gaaacaggcc atccagcagt tatcgctgca gtcgatcaat
    38221 tcgtgacagt cactgtagaa tctgcacgaa aagtcggaag tatccaatct gcacaatata
    38281 gtgggatgcc tgtacgttgg acaagacgca acggagaatt agttttagat attcgggaaa
    38341 atccttttca ttatatcctt gctgctattc gcttgactga aaagtatgca caagaaaaaa
    38401 acattctttt atccttttat gatctgaaag taacaagtga gttagacagt tcaaatggcc
    38461 ggaaatatgg attgggttct agcggtgccg tgaccgttgc aacggtcaaa gccttgaatg
    38521 ttttttacgc gttgaattta tctcagttgg agattttcaa gattgcagca ctagccaatt
    38581 tagcagttca agataatggt tcctgcggcg acatcgctgc tagctgttat ggtggctgga
    38641 tcgctttctc aaccttcgac catccttggc tccaagaaca agaaactcag cattctatca
    38701 gtgagttact tgccctggat tggccaggtc tatccattga gccattgatt gctcctgaag
    38761 atttacgttt attgattggt tggacgggta gccctgcctc tacttctgat ttggtcgatc
    38821 aagttcaccg ttcgagagaa gataaaatgg tggcttatca gcttttctta aaaaatagta
    38881 cagaatgtgt caacgaaatg atcaaagggt ttaaagaaaa taatgtaacg ttgatccaac
    38941 agatgattcg aaaaaaccga caattactgc atgatttatc tgcaatcact ggggtcgtca
    39001 tcgaaacgcc tgctttgaac aaattgtgta atttagctga acagtatgaa ggagccgcaa
    39061 aatcttctgg tgcaggtggg ggcgattgcg gaatcgtaat tgttgaccag aaatctggca
    39121 ttcttccttt aatgagtgca tgggaaaaag cagaaatcac tccactgccg ttacatgtct
    39181 atagcgatca aagaaaggaa aaccgatgaa tcgaaaagac gaacatgttt cactagctaa
    39241 agcctttcat gataaacaaa aaaacgaatt tgacttcgta cggatcatcc ataacccttt
    39301 gccgcaaata gcagtttctg atgtcgatct aagtacacag gcagttgggt ttacactaag
    39361 cagcccattt tatatcaatg cgatgactgg cggaagcgaa aaaacaaaaa aaatcaacca
    39421 agatcttgca atcgtcgcaa gagaagcaga tttgatgatt gccactggtt cagtcagcgc
    39481 tgccttgaaa gtcccttctt tagccgatac ttatacgatt atgcgacaag aatatcctca
    39541 cgggaaaatc attgccaaca tcggtgcagg gacttctgtc gaaagagcca aagaagctat
    39601 ccgattgttt cacgcagatg ccttacagat tcatttgaat gcacctcaag agttggttat
    39661 gcctgaggga gaccgtgatt ttaccaattg gaaagtactt attcaagaaa ctcaaacagc
    39721 cattgacgtc cccctcatcg taaaagaagt cggttttggc atgacaagag aaacgctcaa
    39781 tgatctagct gctttaggag ttcatacagt tgatatcagc ggtcgaagcg gaacaagctt
    39841 cacccagatc gaaaacgccc gtcgctccaa gcgggaactg agttatttag ctgactgggg
    39901 gcaatcgaca gtctcttcat tgcttgaagc aaatgaagca gacacttcta tggaaatcct
    39961 agcctccgga ggtatccgca atgcctatga catatttaaa gccctttgtc tcggcgcaaa
    40021 tgccgtgggt acttcaggaa ccgtactgac gcatctgatg aatcacggcg tagaagaaac
    40081 tattatactg atgaagcaat ggcaagaaga gcttcgtctg ctttatacta tggtcggcgc
    40141 aacgaatacc gcggccctac accaacaatc tctgatcttt tccggaccag tgaaggattg
    40201 gtgcgaagca agagggatcg acttagtgaa gtatggaaga cgcacagaaa agagcgtggg
    40261 acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tacaaacggc ggaagtaaaa
    40321 gcaactcctt cggaaataag ctgaaattca caaaaatttg aaaagcaatt ttcgtgaatt
    40381 ccttcttatt tcttggagtt aaatgcttct gtcccagcct cttttttcga ataaatgatg
    40441 tttaatcagc tgtccttcgg tattcgttca atccgctgat ttcacaacct ctccactaaa
    40501 cagtgtacta aagctctttt aaggttgttt tccgatatag gcaagtatgc ctccgtccac
    40561 atacaagaca tggccgttaa cgaaatcaga tgcgctagaa gccaagaaga cagatggtcc
    40621 agccaaatcg attggctcgc cccagcgtgc tgctggcgta cgtccaacga taaattgatc
    40681 gaatggatga cgttcaccgt tttcttgtgt ttcgcgtaat ggagcagttt gcggtgtagc
    40741 aatataacct ggtccaattc cattacattg gatattgtat tgaccgtatt cagaagcgat
    40801 gtttttcgtc agcattttta atccgccttt tgccgcagca taagcactga ccgtttcgcg
    40861 tcctaattca ctcatcatgg agcagatatt gatgatttta ccgccgcctt tttcgatcat
    40921 atccggaata actgcttttg aaacgatgaa tggggcattt aaatccacgt cgattacttg
    40981 gcggaagtct gccgcatcca tttcgatcat cggtgtccgt ttgatgatcc ctgcattgtt
    41041 gactagaata tcaactgaac ctacatcttc tttgatctgt tgaaccatcg cttgaaccgc
    41101 ttcttcatcg gtcacatcgc agacataacc ttttgcatcg atgcctgctt ctttataatg
    41161 cgctatacct tcatcaactg attcttgatt caagttatta aatacgattt ttgctcctgc
    41221 tgtagctaaa gagcgtgcaa tctcaaatcc aataccatag acagcaccgg tgactaatgc
    41281 tacttttcca tctaaacgaa acatatccat actaaattcc atcattttct ctcccttatg
    41341 cttattttaa ttgatccatt tgcaccatat ccatgtctgt ataggtgata ttttctccgc
    41401 acattgccca gatgaatgag taattgcttg tacctacacc tgaatggatc gaccagcttg
    41461 gcgaaataat ggcttgttca ttgtctacaa ctaaatgttt tgtttcatct ggtttgccca
    41521 tcatgtggaa cacacgtgta tcttcattgg cataatcaaa gtagacataa gcttccatac
    41581 gacgttcatg tgtatgacaa ggcatcgtat tccaagcgct tcctggttct aaaatcgtat
    41641 aacccatttg taattgacag ctttcgcata catttggatg gatgtattgg tagattttac
    41701 gttcattcag tgtcaggcct tcaccagtct ccattggttt tacttggtcg atactgattt
    41761 ttacatttgg atatttatga tgagctggaa cagaactaat atagaattta gctgggtttt
    41821 cagcatcttg agaagaaaat acaacatgtc gtgtttcttt tccgatatag tatccgtctt
    41881 gttttttcat ttcttctttt tgcccatcga tctcgatgaa tcctggtcca ccgatattga
    41941 tcacacctag ttcacgacgc tctaagaagt aatcaacacc tagttctttg tctaatgtga
    42001 tttctaattc tttttcagta ggtgtcactc caccaaagat cattcgatcg ttgtgcgtat
    42061 aagtcaaact gattttccct ggttcaaata ccttttctac taaaaattct tttctcaatt
    42121 gttccgttga ataatgacgg atatcttctg gactgtgtgt ataacgtgtt tccatttctt
    42181 gcattttctt ctactccttc tatcgaatga tttttccaga gccgcatgct aaaaattgtg
    42241 cgacttcttc ttgactaaat tggttgcagt ccccatggat cgtatgcttc aaggcagaag
    42301 ctgccgtagc aaaatcaatg atttcttgcg gagacatatt ggataaaatc ccatggagca
    42361 cgccacctgc aaaagcatct ccgccaccta ctcgatccac gattggggtg attctatgga
    42421 cttgggattc cacatattca tggttcatcc acaatgtccc cttcaattca ttttcacttg
    42481 ctgaatgaac ggtacgcttg gtcgaataaa acacctgaat attcgggaac ttttcctgca
    42541 ttttttgata ataataaatt agaggttgtt cttctgcttc tggcgctttc tcgataccta
    42601 acaaataaag agcatccatt tttccagctg agcagatatc tactaaaggt aaaagctgat
    42661 ggattacttc gctggcttct tgctgtgtcc ataattttcc acgatagttg atatcgaagc
    42721 tgatcaggca gccagctttt tttgcagctt ctatcacctg tttcgtcatt ttttgccatt
    42781 ttttagacaa agctggggtg attcctgaaa catgaaatat atctattcct tggaataact
    42841 cctctagcga ccattccaaa tgatccattt cagcaaaact tgatccggca cgatcataga
    42901 tcactgaggc ggcgcgttcg ccactaccag tttccatata ataagtacct agtcttgatc
    42961 caccagataa tacctgtttc gtatctactc cataacattg caagtgcttt ttgactgctt
    43021 ttcccaatgc gttatcaggt acttttgtag caaaaatcgc ttcatgtccg taattagcta
    43081 aagaaattgc tacgtttgct tcccctccgc cataatgggc agcgaatcgt tcacttgaat
    43141 cgatacgggt tccctgctct gtggacaatc gcaacatgat ttctccgagt gtcactactt
    43201 ttcccataag cagctacctc ttgatttctt tcatttttgc tgcatactgt tgcgcgactt
    43261 ccgttacttt gtcaaaatct cctgtagctg cgggtgctaa aaggttccca cctactccga
    43321 ctgttacgac accagcatcg aaccactctt tcatattgtc cagactcaca ccgccagttg
    43381 gcatgatatt gacttgaggc atcggcgcct tgaaggcaga aatgatactt ggtccataag
    43441 cgcttccagg aaatagtttg acgatatcta ccccgctttt cagcgctgtt ttgatctcgg
    43501 taatagtcat acatcctggt aagtaaggaa tttgatacag attgcacatc tctgccgttt
    43561 cttgatcaaa ggaagggcta acaatatact ctgcgccagc taagatagcc aagcgagctg
    43621 tgacagcgtc taatactgtg cctgcgccaa tcactatttc tggttggtct ttgtagaatg
    43681 acaaaagttc tttgattact tgatctgctt gagggactgt aaaagtcaac tcaataccag
    43741 ttagaccacc tttgatgatt gcgtggcaag cattcaaagc ttcttctttg ctttttccgc
    43801 gtaccaccgc aatcactccg gcgtttttca atcgagataa aatatcaatt tttttcatct
    43861 tctccaccta tttcctattt agaaatttta ttttataact tggaaatcta tacccatatt
    43921 atacggcaga aaagaaaaat tgcaaacgct tttttcatta tttttgaatt ctttgctcga
    43981 tttcgctttt tgtttgcttg agggcactga ttatttgttc ttttgtctca tctgttaaac
    44041 gatatttcgg catacttaca ctaaatgcac caatgatttg ttcgtttttc acgattgagg
    44101 ctcctataca aaaaatatca cgttcgattt cttcatcgtc aaatgcgatg tgggtttctt
    44161 ttaccgtttt gatttccttt ttcaaccgta atgcattggt gatcgtatat tctgtgtaag
    44221 ggatcaacgg atgcttttca agataatcag tgtactgctc ttcactgaat tctgctaata
    44281 cggctttgcc catcgcagaa ttgtataatg gtcgggtgat tccgattttt gaagacatgc
    44341 ggatcgtttg atgttttgga tctagtttgt tcacgtacaa gatctcattg ttgtccaata
    44401 cccctaagtg gatagtctca tcgatctttt gctgcagctg ttctaaaaac ggtaaagtca
    44461 actctaccaa atcgatttgt tcaatgtttt tattcgcgta gcgaataagc tttgcaccta
    44521 aacgatagtt tttctctgaa tttttattta cgtagccgat catcaacaaa gtatctagta
    44581 ttttcaagac tgtagaagag gtcattccca caccctttgc gatcgtctgc aaagagacat
    44641 cttggttttc cgctaaatag tctagtattt tagaggcttt gatcaataca gttccataag
    44701 gctttttatt ttccatataa tattctccta tttctttata agaaaaatta tagcggaaat
    44761 accatcaatt taaaagagat atccagatat aaactaccat ttctctttac aggcaattta
    44821 atgttgaaga tccgcttcgt ttttacatca aactttgata taaagcaatg atttcttcta
    44881 ctgtcgtttc tcttggattt cctggtgtgc atacatctcg caaagcatct tctgcaattg
    44941 ctggaatatc tgcttctttt acacctaatt cagaaatggt ttctgggatt ccaaccgctt
    45001 tgctcaaccg atcgatctca ccacaagccg cttctcttac atcttctaaa gacatttcag
    45061 ctgctccttt aatccctaga acaagagcga tctcacggta cttttctcca gtatattctt
    45121 tgttatattt catgacagtt ggcaaaagtg ctgcacacgc tacgccatga ggaatgttgt
    45181 accatgcact taacgggtga gccatcccgt gtaccagtcc taaaccgaca tttgagaagc
    45241 ccattcccgc aatatactgt cctaatgcca ttttttctcg cccattttga tcgccatcta
    45301 cagaagcttc caaagaatgg ccgatgattt cgattgcttt taaatgcagc atatcagtca
    45361 tttcccaagc gccttttgtg ataaaccctt caatagcatg cgtcatagca tccatacctg
    45421 ttgatgcagc caattttttc ggcattccca tcatcatatc gctgtcgatg aacgcgacga
    45481 ttgggatatc atgaggatca acacaaacaa attttcggtg atttacttca tctgtgatga
    45541 cgtagttgat cgttacttct gctgctgttc cagaagtcgt tggtatagct aatataggta
    45601 aacatggatt tttcgtatca gcaacacctt ctaaactaat gacgtctgaa aactctggat
    45661 tcgtcaaaat aatcccaatg gcttttgccg tatcgattgg cgaacctcca ccgattgcga
    45721 tcaaacagtc tgcctctgcc tctttaacaa aagccactcc atcttttaca ttttggatcg
    45781 ttggattagg tacgatcccg tcgtataaag cataagcgat tgctgcttta tctagaagtt
    45841 ctgttacttt tgttgctata ccgtgctcga tcaatccttt gtcagtaatg acagctgctt
    45901 tgccgaatcc tcgctgctga aattcaggga cgatcgactc aatcgctcct tttccaaaat
    45961 acgatgtttc atttaaaatc attcgattac tcattttcta ttcctcctaa tttgtattat
    46021 ttttcacaat aaaaacgaaa gaaccccaag caaccggttg cccagttgct tgttgctaca
    46081 gttcaaagac tggcatcaat tcccaactga ctggagaggc atctggattt gtctccatga
    46141 tatcttccat gtacttccac catttttgat tgatagatgt atttgccatt ttttcccata
    46201 acttttcatc ttcgatcact aagtaaccaa ataacaaact tgtactcgga tcaagataga
    46261 tcgaatagtc gatgaccccg tgttcacgaa gtgctgtacg catttctggc caaagttcat
    46321 catgtctttt tttgtattct tcttgttttt ctgggtaaac tttcatgcaa aaagcttttt
    46381 tcaccatgtc agacacctgc tttcgtatga acttcctcca aataacctgc ttttggagtg
    46441 acaccaaacg catctgctaa atgccacagg ttttcgtccg tgattgtttg caagattggt
    46501 ccttgcgctt tgacgtacgt atagacttct gctgcctttt ctgctgtctc gatcaaacca
    46561 aagacttcat ccatgtcttt tcctgacccg tagattccat gttgtggcca taaaaccaat
    46621 cgagtttctt tcattttttc agctgttgct tccccaatct catttgttcc cggaaccatc
    46681 cacggaatga tggaaattcc ttctggaaaa acaactaagc attccgtaca catttgccat
    46741 agcgtacgac taaaggaacg ttcgtctaat tcatgcgtaa aactcatcgc taatagatga
    46801 ctagcatggc aatgcataac gatccgatta tctgggtcta cttctaaacg ggcgatatga
    46861 ctcatgaaat gacttggcaa ctcgcttgta ggaaggcatt cgttttccag cccccacaaa
    46921 agttccagtg ttttgccatc ttcagcaact cgaacgattc caagattctc ggcaggttcg
    46981 ctcgctacat ttttaaaata tcttcctgaa ccagttacaa taaaatagca tcctgctaaa
    47041 cggctggcat caaaaatcat cgagatgcgg cggatcactt tttcaggatc caagaacggt
    47101 gtgatctctt cttcttttag taaataagaa atattcccgc catttctttc atcccatccc
    47161 aagcgataaa gattcgacgt cgtttcgatc atttctttca cataaggcgc ttgtaaaata
    47221 tctatttttt tcaatatagc cacactccta ttttcttaat tccaacacgt ctttttgata
    47281 ttcctggact tcttccagcc aatccaaacc aactggaact tgatttttgt aacagaaata
    47341 attccataca tcggcatacg ggaaatcttt caattcttcc gtataagcca ttcttgaagt
    47401 aaagtcaaaa gccagctcca tttctttcaa tcgctcaact ggttccagca tagctttcag
    47461 cagtgctttt tgtgtatttc tcgtaccgat gacccaagca gcgatacggt tgatcgttgc
    47521 atcaaagaaa tccagaccga tatttgtttt ttccaacaat tcgttacgga ctaattcttt
    47581 agcgatttcc tgcaattcat catccatcaa aaccacatgg tctgaatccc aacgcactgg
    47641 acgggaaaca tgcaacatga ttcctttgct gaataaagct aatgaagata atttattgga
    47701 aatcacttct gttggatgaa aatgtccagc atctagacaa acaagtttgt cacgagtcaa
    47761 cccgtaaccc atataaaatt catgggaacc gactgtataa gcttcagcgc ctaaaccaaa
    47821 tagtttgctt tctactgcat cttgtacata ccgttcatct aactcttctg taaaaatttc
    47881 atcgagtgat tccattaaac gttcccgtgg ggtaaaacga tcaatcggat tatctttcat
    47941 cccatcaggt acccaaaagt tattgatact tgtttgccca gtttctttcc caaagtactc
    48001 cgcgattttg cggcttcttt tcccgtgttc gatccagtat tcacgaactt ctttatctgg
    48061 atgagccaat gtaaagccgt ctttcatcat tggatgcgaa aagaaagtcg gattgaagtc
    48121 aagaccgatt tcttcttttt ttgcccactc tacccatttt tcaaaatgtt tcggctcaat
    48181 ttcatttaga tcgacagatt cttctgtatc caaatagata gcatgaaggt tcaatttgtg
    48241 tttgcccggt atcaacgaat aagccttctc cagatcttgt ctaagctctt caggtgttcg
    48301 tgcggctcct ggaaaattcc ctgtcgccat gattccaccg gtcaattcgc catccggtgt
    48361 caagaaacct ttgacatcat ctccttgcca gcaatgcata gaaattttga tgtcctgtat
    48421 cttttctagt acagcatctg tatctacacc gatagttgca tatttttctt ttgcttgttc
    48481 gtaatttctt tcaatcgtgt tcatacgatt actcctttga ttttattcac gtaccattcc
    48541 atcgtgtttt gcttattttc atctgggtaa aaagtttcac atggaaacga ctgtttgatt
    48601 acatttcttg cttgttctat attcgaaaac tgacctgtac tgagcatttg catggcaaca
    48661 ttcccgattg ctgtggcttc actaggtcct gcttctacaa tgattccggc ataatctgct
    48721 gtcaattgat tcagtagacg attattcgat ccgcccccta cgatgtgcag cttttccaat
    48781 ttcgttccag ttaagtgttc tactttgatc agctcttgtg cgtaacaaag agcaagatta
    48841 tcatacacac aacgagcgat agctcccgat gagacaggga ctggctgctc tgtttcaaaa
    48901 cagtattgct gaatctcttc tatcatattt gggggattca aaaatcgagg gtcattgatt
    48961 tccatcactt gctgcagcgg tttttctttt gcagcaagct ctgccaattc cgcataactg
    49021 tactcgtact cttgcattcg ggcaacttcc tggatcaacc acatccccat gatgtttttc
    49081 aaaaaacgca ccgtgttatg ggcaccccat tcattcgtat aattttcaga aaaagcattg
    49141 cgagaaacat tggcgatctt tgtttcaatc cctaaaagcg accatgtccc actgctgata
    49201 taaccccaac gttctccttg acctggcgtt cctaatacag ctgacgccgt atcatgactt
    49261 gctactgtga taaaggtcac atctggcaaa tcatattttg aaaattgttc tttttgcaga
    49321 tctcctagta tcgttcccgg ctctgtcaat ggtggaaata attccttcga gacaccgatt
    49381 ttttcaagaa gttctatttc ccattctttt gtccctgcat tcagcagctg catagtagat
    49441 gcattagttt tctccgtcac catgttacca gtaaagacat accctaaata atcaggtatc
    49501 agtaacaatt tatgtgcttt tgccaaattt tctttttctt cagcaaacaa ttggaacaag
    49561 gtattgaaag gctggatctg aatccctgtc tgctcataca acttatctag agaatagatt
    49621 tcagaaaact gttctactgc tccattggta cgcttgtccc gataagcaat cggatcattt
    49681 atccgatccc cttgttcatc aatcagacag taatcgactg cccatgtatc gatccccgca
    49741 aaaaggcgat caatccctgt ctgctttaat ttttcaaatc caatcaaaat ctctttgata
    49801 agataatcga tcttccagcg atcgtgaccg tctttgttcc gaaagccgtt tttgaaccgg
    49861 tgtacttctt ccaagatcaa agaacctttt gcatccctcg tacttttcat tagtcgtccg
    49921 cttgatgcac cgatatcgat ggcaacaaat gttggattca tttctccacc tcttttactt
    49981 tattgttgat tagcacttta ttaataaagc gttatcattt attgacaatg ctatcataat
    50041 acagaatctt atattttgct tcacactatt ttggtatata attgcattat cttgacaagt
    50101 tgggagtgtt tacatggatt actgggaaaa agccaaccac tcatggtcgg aagactcaaa
    50161 aagagtgatc ttgacgccta cacaaagaag caggaattta tttttttata tccaagaaat
    50221 cggttacttc aaagcaccaa tcccttacta tactgaacga gcacatttac cttcttactt
    50281 gataaagttt actttgtctg gcaaaggttc gcttacatat aatgataatc agcaacagct
    50341 aaaagctgga gacttatttt ttattgactg ccaagaatat cagcgttatc aaacgatcag
    50401 cgaagaacca tgggaaatgg attggatcca tttgaatggt cagaacgtcc aatcatttta
    50461 tcaggagttc acaaaagacg gccataacac cttccattca acaggagatc catcagaaaa
    50521 caagatccac catttgatca cagaattgat ccacatgcaa caaggcacga atgcccgtac
    50581 cgatttccag tcctctgtag ctatccacga gttgctgaat gaactgattt tgcaaaagta
    50641 tcagctagat ttcgaagaag aggatattcc cgcctacgtt tacaaactga agcaatactt
    50701 agacgaacat ttcaaagaaa cgattacact tgatcaatta gaacaacaat tcttattgaa
    50761 taaatatcag ctgagcaaag atttttccaa atttatcggt tctccaccaa tcgattattt
    50821 gatcagcaaa aaactttctt acgctaaaga ccttcttcgg tatacagaat ttacggttcg
    50881 aatgatttcc gaagaaatag ggattgagaa ttttgcttac tttagccgcc tgttcaaagc
    50941 aaaaacagga ctatcgccga gagactttcg taaattcagc tgattcatat aatatgtacg
    51001 tcattttttc aaaatatttt gaaatatata gataaaaata aaataaccgc agtttctgct
    51061 tctatgtaaa caacagcagc tactgcggtt attttttagt gatcattctc attgttcatc
    51121 ttcaaaatgt tcataatgaa ccaactgttt ctgtgtatca cgtttcaaaa attctttagg
    51181 cgttatgccg aactctctct tgaatgcttt cagaaaatgc ggataagaag aaaaaccact
    51241 tttactatat acagcactag agctgcggta ttctcgcaac aagtgcttgg catagatcag
    51301 ctttttcttc attacatact gatgaaacgt aaatccagtg tactttttaa attctcgtgt
    51361 gatatggtat ttgctgacaa aaaactgctt ttccatttcc tctaaagaaa gcggatgaga
    51421 taaatttttt gagatatatt gtaacatttg ttccacacgc tcattaggaa ctacagcatt
    51481 ctgttcttgc gcactctctt ctttttgtac aacttgattg agaaaaatca agtattctac
    51541 cagagcttgt tcatatttta tgtcttcacc gtaaattttt ttatcaggag gatggtcgat
    51601 aaatgataat ttttgcttca atacttcctg ttctatttgc aatacacgac tcctcttctc
    51661 tcccattggt tgaaaacaag ccgatagatt agaccatggc gtggaacgac tttctagaaa
    51721 agaaggggtg acaaagatat agacacgctc gaatacatct gaagattggc ggacgatacg
    51781 atgcaaatca ttggaatgga tgagcagcac acttcctgct ttgatcgtaa attgtcgtcc
    51841 gttcaaataa aaagtcgctt ctccctttaa tgtagcatgg atctcataga aatcatgatg
    51901 atgatagatc gttttatttt ggctgacgac atctttgaca tgatagattt catactgatc
    51961 agaaaccatc gtattgactt gttcaccgct gattttcttt tggagcatgt gccgcacctc
    52021 cttttgttca cttatgcaca attttattat accacgtttt ttgtaatcaa aaagagctgc
    52081 ttttatatac tcttataaaa aagaagagac gtggcatctt ctagccccgc cccctccatt
    52141 ctaaatatta gttaaccaac gtcttcttta cattattcaa gaagacttct tccataacga
    52201 atcccatcat cttttgtttc ttcaagaacc acatacaggt acggacgatt cttcatgatg
    52261 atttctttga tttttgtgta ctcgatcaca ccgtctccca aatttaccgg cacgattttt
    52321 tcctgttcga cacgaaaatc tttcaaatga accgcacata tcttttcacc aaaacgttca
    52381 aaagcttctt ctaccaattg gacttgttct tgataatcac tacttgtgat caaattggtc
    52441 ggatctaaaa tgattcctag atagtccgaa tctactgctt ggatcagctg ctctaccctt
    52501 gctaaagaat acaccggatg attcaaacct ggttctatcc ccaccatcat ttggtatttt
    52561 tctccagctt ttaccaagcg acggataacg gacacagctt cagcaaatgc ttcatctgtg
    52621 aaattttctt ccgtatattg gatttccggc aaaacacatc cagtttccga agcaaccatc
    52681 gacgcaccaa aggaagaagc atagcgaaga tactgctcga actttgtcag caactcttgt
    52741 cgtatcgtta aatctggatg aatcatattg atatagcaac ttaaaattcc tacggtcact
    52801 tcttgctttt ctaaaactcg tttgacataa tttcccatcc cagaattgat ctcatttgcg
    52861 ccagaaggta tttcaggaaa cgaaagacct aaggcgagct gcagtgtatg aatcccttgt
    52921 tcttttgttt tttctgcaag atcttctatc gtttggactt cggaaagatc atgtcctcta
    52981 attgtaatgt tcaacataac tattctccta actcagcata ttgggtagcc acatgacgat
    53041 ttgcgggaag taagtaatca aaaacaagac gactaagata accccataaa aaggaagaag
    53101 cggtttcagc attgcctctg cttttacgcc tcctacactt gcaccgacat atagtcctgt
    53161 acctactggc ggcgtgatgg agcctacaca cagattcatg attgaaaaca acccgtaatg
    53221 tacaggatca acccctacac ttgtgacgat tggtaaaaat attggtgtaa aaatcaagat
    53281 agcaggcgcc acatccataa acatacccac cagtaataac acaagattga ctaataacag
    53341 aataataaat ttattatccg ttacgcccat aatcaacgaa ctaattgcct gaggaatacc
    53401 ggtaaacgcc atggcgaaag acatcatgga agaagtagcc aataagaaca tgatcgtccc
    53461 tgacattgct actgattgaa acaacatatt aggtatatct tttagtttta ccgttttata
    53521 gtaaaacata gcaatcaaca gggagtaaat gacagctatc gctgaagctt ctactgctgt
    53581 aaatatcccc gtcaagatac caccgataat gatgacaatc aatagaaggc taggaatcgc
    53641 ctcttttatt atttttccag catgagccat ctgtcctttt tcgacaacag ggtatttatt
    53701 ctttttagca acgatgaatg ctactagcat gattcctagc gcccacaaag cgcctacgag
    53761 ataacctccc ataaacaaag cagagatcga agcaccacca gcaacaagtg aatacatgat
    53821 aaaagcagta cttggaggaa tgaccatacc tgtcggagct gacgcgatat tgaccgctgt
    53881 cgcaaacttc cggtcatatc cttcttccac ttgctgaggg atcaacactc cgccaatcgc
    53941 ggtagaagcg gcaatggccg agctagagat ggaaccaaat aaagcattcc ctaacacatt
    54001 cgtatgagcc aaagcccccg gcacgcgccc gacgaacaac atcgcaaaat ccactagttt
    54061 cttagctatc cctccattat tcatgataat gcccgagaga acgaaaaacg gaatagcgat
    54121 cagcgaaaaa ctattgatac ttcccaccat tttttgagct gaactaaaag cagaaacatc
    54181 aaacggtata actaacaata aagtcatcat cgatgagaat gcaatactta tagcaatcgg
    54241 catccctaat acaagcaaca caacaaatac aaaaaataac actaatccgg cttctattgc
    54301 cattttattc ctccattttt atattttttc ttgaattgct ggcttgttgc ttaatgtatc
    54361 gattagattg atcaggctat agataatgat gagtaccccc gatacaggta ctgacagata
    54421 aacatatccc ataggaatac ttaaagaagg cgagatctgc cccattgtca atgtgacagc
    54481 attccatccg ccatacacca tgatcatcgc agcaaatacc agaaataaac tttgaacaac
    54541 aacttctaaa attttacttt ttttgccagt taatttttca cttaaaaccg ttacggctaa
    54601 atgtgctttt tgtcccacaa catacgcgga agacaacatg gcaaaccaga caagaccgaa
    54661 tcgaacaagc tcttccgtga ccgtatttgg atttcctaaa accgttctgg aaaatacttg
    54721 ccataaaaca acagcgacca tcccaacaag caaaacagct cccaggatct ctaatacctt
    54781 gtttaaaatc attttcatca cagctacgct ccttgctctt ggatcttttg ataaaggtct
    54841 ttgtaggtag gatcgttttt gaatatatca tgaagtgggg caactgcctc tcgaaacggt
    54901 gtattatcta catcattgaa ttggactcca tgttcttctt gtgctaaagc tttttcttct
    54961 tcaattgctt ttgcaaaagc ttcaatttca aaaaccgttg attctttcgc tgcttcttca
    55021 atggcttttt cctgctcatc agttagctgt tctttgatgg catcattcat gatgatgata
    55081 tctggcacac gtgtatgctc atcataggaa tagtatttag ccacaccacc atgtccagct
    55141 gtatacaaga caaattcatt gttttctgat ccgttgatca aattggattg aagagacgtg
    55201 tacacttcat cacttcccat aggtacgggc gaaccgccta aaagctctac cattttgata
    55261 gcggtttcgc tttgcatcac acggatcttc tttcccttca aatcttccgg cgtatggatc
    55321 ggaccgtcta ccatataaaa gctgcgctga ccagaatcat aataggtcaa tccggtaaat
    55381 cctaaatttt tggtcgattg gtagattggc tccattattt cttcattatc catcacctta
    55441 aagaaatgtt cttcatcatt gaatagataa ggaactgaaa aaatcgaata atctttagag
    55501 aaactttcca acgctgaggc acttactttt gtgaaatcta ctgctcctga ctgtgtcaat
    55561 tcgatcagtt cacgttctcc acccagttgt ccatctggga aatactggat ctgtacggaa
    55621 ccatctgttt tttcttttac taaacgccca aattcattca ttgcatcaat tactggctgg
    55681 ctgttgcttg cataagcaaa gcgcaaggta actatctcat ttacatctgc atctgcgaca
    55741 gttgccacac tagaattatt tccgcagccg cttagaccta gcagacctag gctaagcgaa
    55801 cttgctgcaa acagcagtga tgtttttttc atatgggttt cctttctttt aacaataaga
    55861 gacgagcaat tctgtcaaac aaagcaccgt taacgactgt ccataaggca ttgctgtgat
    55921 tccgatattc cgataaaaat ctaaactgtc ccccattcct gtcccgattg aaacgttttg
    55981 aacttctcct ttttcatcga tttgttcaag caatccttgg atagcacgat aagcgacttc
    56041 tttatattct tgtggtaaat aacgtttatg gaccgctttc aaaataccgt aagcaaatcc
    56101 tgcagttgca gaagattcta cgtaagaaga aggatcatcc aacaacgtat gccataaacc
    56161 gctttcagac tgataagttt ttaatgcacg cacttgtgct tcaagtgttt cgatcaataa
    56221 tttgcgcaat gcatcttctt tcgataattc taagatttca atgatctctg gaatagcaat
    56281 cgtcaaccag cagtttccac gagcccaaaa tgcttcggca tagttatgat ttccttcaaa
    56341 cgtccagccg tgataccaca atcctgttcg tttatccatc aagtatttga tatggatcat
    56401 aaactggtaa cgagcttctt ctaaatattc tgggcgattc aacagtttcc cgatttttgc
    56461 caaaggaagc actgtcatca tcaatgtatc gtcccacaac tgattcttat tttccggtcc
    56521 atatgtggca tgctgtaacc cgtcttcatt tgtccgaggc atgtcattca tgacccattc
    56581 tgcccattgt tctaaataag gcaaatagcg tgaatctttc gtgtcttcat acaagtaagc
    56641 catagtcaat agcggtgcca ttgtattgac gtttttgggc ggagcgcctt cttccatacg
    56701 atcctcaaac cattcattga ccacttgata agcgcgagga ttttttgtca tctggtaatt
    56761 tttataaata ccatatagac cgacaccttg tggccaattc cacactgtcc agcttttgtc
    56821 atctactttc agtccatcaa agtccaacaa aaattcacca ttatcgtctt tgatcgttgt
    56881 caggttttca acgagcaggt caattttttc tttcactaat tctttaggta caaaaatctc
    56941 ttctttaata atcatcttta cgccaccttt ttaaacgctt tcattttata tccttaatat
    57001 agcagtaata ccgtccacta taaatatcgc tttttgaaca aaaactgtct aaaattgacc
    57061 taaatgttaa ataacaaaag taactttcag ttacttggaa attaaaaaaa gaacttggcg
    57121 aaacaacgtt ttccaagttc tttttcatct attttcttat cttttttcta cgctttcttt
    57181 tgcttatccg ttgtaagcat caatgatgat ctgtttcaat tcagagatca atggttcttt
    57241 cggattagct gtcgtacatt ggtcttcgta agctaattca gccatacggt ctacggttgt
    57301 atctagtgtt tcttgtgtga ctccttgagc ttttagactc atgttgatgc cgacagattt
    57361 tcctaattca taaacagccg ttgctaaagc ttcgactaat tcctctgttg tttcgccttt
    57421 cagacctaag aattttgcga tatctgcgta atctgtatct gcacggaaat agtcatattt
    57481 agggaacatc gcatgttttt gtggatcttt tgcattatag cggataatat gcggtaaaag
    57541 aatcgcattt gtccgtccat gagggatccc gtattccccg ccgattttat gtgcgactga
    57601 gtgacaaata cctaggaatg cgttagcaaa cgccatacca gccattgtag aagcgttgtg
    57661 cattttttca cgtgattcca tatcaggtgt ttttactgat ttttctaaat agtcaaagac
    57721 taacttgatt gcttgtaggc tcaatccacg tgtataatct gaagccatga ctgaaacata
    57781 ggattcgatt gcatgtgtta acacatccat cccggtatct gctgtgacag atgctggaac
    57841 tgacatgacg aattgaggat cgacgattgc gacatctggc gtcaatgcat aatctgctaa
    57901 cggatatttc acatgtgttt cactgtcagt gatgaccgca aatggcgtta cttcagaacc
    57961 agtccctgat gttgtcggga tacatacgaa ttgtgttttt tctggtttgt cgatcttata
    58021 tgtccgttta cggatatcca agaatttttg ttttgcacca aagaaagatg tgtctgggtg
    58081 ttcatagaac atccacattc ccttagctgc gtccattgca gaaccgcctc caagagcgat
    58141 tactgtatct ggcttgaagt ctgccatcag tttcgttcct gcgtatacgg tatttgtcga
    58201 tgggttcggt tcaacatctg agaagacttc gatcttcaca tcatttttac gtcgtgccaa
    58261 tacttcacga actgtatcgc agtaaccgaa ttggaccata ccagggtcac aaacgatcat
    58321 gacacgttca acgttttcca ttttctctaa gtacaataga gagttctttt caaagaagat
    58381 ttttggcggt aatttgaacc attgcatgtt atttctccgt ttcgctacag ttttgacatt
    58441 gattaagttt acagcagaga cgttacgaga aacagagttc ttaccataag aaccgcatcc
    58501 caaagtcaat gacggaatca tttcgttata gatatcaccg atgccgcctt ctgcagatgg
    58561 tgtattcact aaaatacgac aagctttcat tcgaagaccg aatttgacat gcaactcttc
    58621 gttttctgaa tggataactg ctgtatgtcc taatcctcca agattcaaca taccttcaca
    58681 caaatcaaac gcatggtccg tgttgttagc tttgatcatg gcaagaactg gagaaagttt
    58741 ttctcttgat agcggataat ctgggcctac gccttccaat tcagcaatca gcattttcgt
    58801 tccttttggt acactgattc ctgccaattt tgcgatttcc atcgcagaat gtccaacgat
    58861 tgatggattg accgcatatt ttccttcgtt catcactgca tcttctaatt tttgcaattc
    58921 atctggtttt acgatataaa cttggtgtgc ttggaattct gcttttactg ctgcatagat
    58981 ttctttatcc acgatcacag cttgttcaga agcacaaatc attccattat caaatgtttt
    59041 cgaaacgatc aaatcgttca ctgcacgttt aatttttgct gttttttcaa tataagctgg
    59101 tacgttacct ggacctacac ctaaagctgg ttttcctgta gagtaagcag acttgaccat
    59161 tccagctcca cctgtcgcta agacgatcgc gatacctgga tggttcatta gcatagaagt
    59221 cgcttcgatc gaaggatgtt cgatccattg gatacaattt tcaggagctc cggcagcgat
    59281 agcagcatca cgtaccactc gtgctgcttc tgcagaagat ttttgggcac ttggatggaa
    59341 agcaaaaacg attggatttc ttgttttcaa cgcgatcatt gatttgaaaa tcgttgtgga
    59401 agtcggattc gttgttggag ttactccgca aaccacaccg actggttcag caatttcaat
    59461 caaccctttt tggacatctt cattgatcac accaactgtt ttatcatgtt tgatattatg
    59521 ccaaatatat tcggacgcat acatattttt gattgcttta tcttcgtaaa caccgcggcc
    59581 tgtttcctct acagccatct tcgctaatgg catatgttga tccaaagctg ccattgccat
    59641 ttcatgcacg atatggtcta ctttttcttg atcaaagctt tccatttctt tcaatgctgc
    59701 atttgctttt tctgccaaat catcaatcat tgcttgtacg tcaattgtct tcgttttttc
    59761 tttttctatt actttagcca tcattatcct cctaatgggt catggttatt tgttaaataa
    59821 ttcacatgta tatcatacaa tatttatttt tctatgtaaa cacttttttg tgattttttt
    59881 cacagttatt tttaaatata aaattgcttt atttacaggt gtttgtatag aaaaatatat
    59941 aaagttattt attattattt atatgacaca cccgattatt caatattgag caatatatcc
    60001 catgctctta tctctttctt ttttgaataa aaaatgaggt aggacatctt tctgccctac
    60061 ctcgtcttta aataagcttt gatacttatt tttcttcctt ctcttctgtc tcttccagcg
    60121 tttctgttgt ttcagttttt acttcaactg tctcagctgg ttcttctgtt gtttcaacag
    60181 tagtcgttgc atcatttgtt acgacagtcc ctggtttgac cgttttgatt gctgcacgat
    60241 cgtactcaag gaagatccct tcgcagtcta aaacaactgt ccgtttgtca ttgtcgattt
    60301 ctgaaacaac tccatgtaat ccgccgatcg ttacgactga atcacctggt ttcatgctat
    60361 ctaacaagtt ttgacgttct tgctgttgtt tcttttgcga acgtgacata aaaaaccaca
    60421 ttgctaatag cgcgataaac atcacaagca ttggtaatgt tcccattttt ttcacctcac
    60481 taattctgta tctacaaaaa acactttagc agaaaaatgc tgataacact agttttttac
    60541 ttaattttta aaagattttc ctttagaagc tttttgcgtt ttctttattg aacccgtatt
    60601 cttcaaaaaa ggcttctcta aattcaagca aattatcatc catgattgct tgacgtactt
    60661 gtttcattag attcaacaag aagtataaat tgtggtaaga agtcaaacga atcccaaatg
    60721 tttcatcaca tttgatcaaa tggcggatat aggcacgtgt atagttttta catgtataac
    60781 aatcacattt ctcatcaatt ggacggaaat catgggcata tttcgcattt ttcactacta
    60841 gacggccttg agaagtcata catgtgccat ttcgagcgat tcgagtaggc aagacacagt
    60901 caaacatgtc tactccacgg ataacaccat cgatcaatga atcagcagca ccgacaccca
    60961 tcaagtaacg tggtttgttt tcggggatca acggtgtagt gaattctaat acacgattca
    61021 tttctgattt aggttccccg acagataacc cgccgattga gtaaccaggg aaatccatcc
    61081 cgactagatc tttcgcgctt tgacgacgaa gatcttcaaa ccctgctcct tggatgattc
    61141 caaataatcc ttgacggtct ggattagcat gagctttcaa tcctcgttct gcccatcgag
    61201 acgtacgttc tactgatttt ttcacgtagt cgtaactttc atcgaatggt ggacattcgt
    61261 caaaactcat catgatatca gagcccaatt tattttggat gttgattgct ttttctggtg
    61321 ataaaaacat acgcgaaccg ttcaagtgat ttttgaaatg cacgccttct tcttcgatat
    61381 tccgcatatc acttaatgaa aaaacttgaa agccgcctga atctgttaaa atcggttgat
    61441 cccagttcat aaatttatgc agtccgccag cttcttctac taagtcttca ccagggcgta
    61501 gccataaatg atatgtatta cttaaaataa cgccagcacc catttctttc aactcttctg
    61561 gggacattgt ttttactgta gctaatgttc ctactggcat gaacattggt gtggggaaag
    61621 ttccgtgtgg cgtgatcaat tcccctaaac gcgcgccagt atgtttttct ttcttgatta
    61681 aacgatagcg aatggcaggt tgcgtcattc atttccctac tttctatata aaatatcttg
    61741 acaactccca ccatcataat cgtttcaagt gctttttgca agttccctcg gcttccttct
    61801 actttattta atattctttt ttttatcctt tttttatgaa taacaaaaaa aagaaaaaca
    61861 ttatgacaga aatatttttt gatacatggt atattggtgt tattaaagaa aaggagggaa
    61921 aaatcatgca atcttctgca gaattaaaac gccaagcaaa agagagtcta aaaggacgtt
    61981 ggggacaagc tgttttacta aatctaatcc ctacattgat tggtattgct actattcttc
    62041 ttattatgat tcctattatc ttgtttgcca ccaccatata tgatggatca gcgagcgtct
    62101 cagaagcgac aacttcagga ggcggtagtt caggaggcgg tggcggaatt atttccagca
    62161 tcattagcgc tttgttcatg agcggtattt cttggactta tcttgatatt ttacgtggac
    62221 aaaaagatca gatcgaacca ttcaaagatg catttcgtgg attcaaaggt ttgtttatcg
    62281 gcggagtgat cagcttagct gtgctgatct cgatctttac aacattatgg ggtttgctat
    62341 tagttattcc tggaatcatt aaaagctatt cttattctca aagctatttt atttactacg
    62401 atatcgtcca agaaacagga caaacaccta aagtactgga tacgatcact gcaagtcgaa
    62461 aattgatgga tggttataaa ggacaacttt tctggttaga tctttcattt atcggctggc
    62521 atatcttagc attagcaact gctggtattg gttatctatg gctcagccca tacatttctg
    62581 caacaaaagc agcattttat gaacaattgc caaaagatat ttaaaagaga gtgtgacttg
    62641 tgaccgaggg ggtggcagga gaacaccgtt tatcgagagg cagtaaaaga aacattcagc
    62701 ccattagcaa aaaggaggtg tgacaacatt catgtcacac ctcctttttg tatagttcca
    62761 gtaaaaagaa aatcaactta gaaacagtta atcattcctc ttcttctgct tccggtaatc
    62821 gatggaactt gatcagttca ttcaccgcga ttggtacgat agataaaatc cctaccaaga
    62881 accagtgatt caaactgatg tgtactaggc cgaatagttc ttgcgtaaat ggcagcaaag
    62941 caacagccgt tgtaatagct aatgccagta acgccatttc taccaaagct ttattggtcg
    63001 ctaaattgac tttgaagatc gattggctgc tgcgtacatt gaacacatgc agaatcgatg
    63061 aataagctaa gatcaagaat gcaacagttt gaccgacatg ctgacttgcg tctacccatg
    63121 ggctgatagt atcgacataa ctacctaaat aataaccaaa caaggttacg atggtgaaga
    63181 cccctgcatt tatggcaatt ttttgcaata aacctcgagc aaagatccct tcatttttcg
    63241 gaatgggtgg ctgatccatg atgccgtgtt ccgctggctc tcttcctaaa gcaaatcctg
    63301 gaagtccatc agcaactaca ttgacaaaca gtagttgcac agctgtaaat ggtgctcccc
    63361 atcctaacag catcgcaatc aaaacaataa agatctccga aatattacag cttagcaaaa
    63421 agttgatagc tttacgaata ttctgataaa ccgaacgtcc ttgactgaca gcgtctacga
    63481 tcgtcgcaaa gttgtcatcc gtcaaaatca tatctgcggc actttgcgcc acatctgttc
    63541 ctgtgatccc catggcacac ccaacgttac ttgctttcaa cgctggtgca tcattcacac
    63601 catccccagt catcgctacg actgcacccg tacgttgcca agatttgacg atccggatct
    63661 tgtcttctgg cgttacccga gcatagacag agagagcttt gacacgcgca tctaattctt
    63721 cgtctgataa ttgatgcagt tctgatcctg aaagtgcttc tgacggatca ttcaagatac
    63781 ctaattcttt cgctatggca ctggcagtca ccacatgatc tccagtgatc atgactgttt
    63841 tgatgccagc ctttttcgct cgcttgattg ctcctttact ttctggacgt ggtggatcga
    63901 tcattccgat cagaccaatc aaacgtaagt ctttttccag tgcttcagaa gaaatatctt
    63961 gcggttcttc gtcataagta gcataaccaa cagcaatcac tctcagtgcc cgtttaccaa
    64021 agcgatcatt aacgatcgcc gcttgttcta catcgcctga actaaagcgc ggagcaagaa
    64081 catcgaatgc tcctttggtg attgagatgt atttttcgcc catttggtga actgttgtca
    64141 tcatttttcg ttcagaatca aaaggaagct cgtttactcg tggatatttt tcttctaatt
    64201 ctgcctttgt atgataattc tcttcaacag cccttacgat ggctacttct gttggattac
    64261 ctttgataac aaggtcgtca tcttcttgct cgaccgtcac atctgtacat agtgcagcca
    64321 ttttcaatat ttccatcgcg ctgttcgtca ttgaatcttc gatattcgtt acttcatctt
    64381 ctttgctcca tacccggcgg acgcgcattt cattttgtgt cagcgttcct gttttgtctg
    64441 agcagataac attagcggtt cctagcgttt caactgctgg caactgtcgg atgatcgcat
    64501 gtttcctcgc catcttctgc acaccgtatg caagtgtcaa cgtaacaata acagtcaagg
    64561 tttccggtac agctgcaaca gccaaggaaa tcgaagtcat gaacatctca aggagtggtt
    64621 ctccttgcag ttcaccaatc acaaatacta aagccgcagc cgctaaagcg atcatactga
    64681 ttcgtttgcc tagctgattc aatcggacct gtaaaggtgt tttttgcata gtattttcgt
    64741 tcaaaagatc cgcgatctta cccatttctg tagccatgcc aatggcagtg acgatcgctt
    64801 tcccacgacc tgcagcaacc gtacatcctt taaataccat attaagttgg tcacctaatg
    64861 actcatcttc ttcagcaata aatgctgcat ctttttcaac tgcttcactt tctccagtca
    64921 acgccgattc ttctacacgt aattgtgatg cttcgatcaa acgggcatcg gcagaaatag
    64981 catcaccgga ctctaaaaca agaatatcac ccactaccag ttgctctgac tcaacagtgg
    65041 tcactttgcc gtctcgtatg acagttgccg tttgtttatt catatcttgc aaggattcca
    65101 gtgctttttc tgcgtttcct tcttggacaa tcgccaatac cgagttgatc acaacgatag
    65161 cgatgatcag cagtccttca aataaatccc catgttctgt agcaaatgcg gtataaaagg
    65221 aaatcaccgc tgctacaaga aggatgatcg ttgtaaaatc ggacaagctt cgaaagaatt
    65281 ttttgatcat cgattctttc ggcgcctcat cgaatttatt caatccctgc ttttttcgcc
    65341 gttcatccac ttcttgtgaa gacaacccag tatctggatc tgcttctgtt accttcttta
    65401 cttcttctat tgtctgcttg tattcttcca tcctattcct cctttaaaat cttcgtacaa
    65461 aaaaaggtac ttattttact ataacatcct ttttttattt acttcaaata aagggcttat
    65521 cgattatttg ttaagaaagc gtaaaattta aagtgcttat atttgcaaac gctaccaaag
    65581 gatgctatta tatagatgta aggaaggagg ataccatcaa atagacagaa gaatttctcg
    65641 atagaacagt gtaagcaaac aaagttgtta gaagtacagg tttcacccag acatgcgtgt
    65701 agagtacaaa cctataaata gtgaatgcgt atggatgttt ggatcacgaa gtatccgaaa
    65761 caagaagtaa tgcgatacgt aacaattgaa taacgtaaac gtctgaaaat tgaataggaa
    65821 caagagatgt ttcaaatgtt gaagatgtaa cgaaaacaaa atttttgttt aacatgaaga
    65881 aattcaacac cgtgctttgc atgtatgatg gaaagttaca atcatttctg tttatttgaa
    65941 tccttccgag gtacaagaaa gccgagctta tcgagagctc ggctttttct ttgtcataaa
    66001 atctttgtaa agcttttttg ttattcaaaa ctagcggctt ttcataacct tatttcacga
    66061 acatcgcatc tccaaaacta aagaaacgat agcgctcttc aatcgcatgc tggtaagcag
    66121 ataaagtcaa ttctcttcct gcaaaggcac taactaacat gactaaagtc gattttggca
    66181 aatggaaatt agttgagaaa gcttctacca ctttgaattc atagccaggc gtaatgaaaa
    66241 tatcagtcca tccgctgtct gctttgattt ctccattaaa tttcgttcca atcgtttcta
    66301 atgttcgaat tgaagttgtt ccgacagcca cgattttccc gccattttta cgtacttggt
    66361 tcaatcgctc agccgcttct tccgtcaaac ggtagaattc actatgcata tggtgttctt
    66421 caattttatc tacgctgaca ggtcggaatg tacctaaccc tacatgtagt gtcagataga
    66481 ctaattcaac accctttgct tcgatctcat caagtaattc tttcgtaaaa tgcaatccag
    66541 ctgttggcgc tgcagcagaa ccattttctt tcgcatagac agtttgatag cgatctgggt
    66601 cttccagacg ttctttgata tatggaggca atggcatttc tcccaatgat tcaagaatct
    66661 ctagaaaaat tccttcatac tcaaagtcaa tgatccgtcc gccgtgttcc aattcttctt
    66721 tcactactgc ttgcaatctg ccatcaccaa aagagattct tgtcccaact ttggcacgtt
    66781 tcgcaggttt gatcaatgtc tcccacgtat ctccttgtgt attcgttaga agaaggactt
    66841 ctaaatgcgc accagtatct ggtttttctc catataaacg agcaggcaga actcgtgtat
    66901 tattcataac tagcgcatca ccaggctgta actcttcaat gatttcatgg aaatgtttat
    66961 cttccatctc tccagttttc cgatccaaaa caagtaaacg agaatgatcg cggtctttta
    67021 atggtgtttg tgcgattaat tcttccggca agtcaaaatc aaaatcttct gttgttaaca
    67081 tatcgtcact cactttctat catgtgcttc atcattctat catgtttttc gttctgttgg
    67141 caaaatcagc actttttcac ttctattttt tgttttccta aataaaaaaa ctaccctatt
    67201 tgtatttttt cattgtttta ggcatactag taatagatag ttcttcattg aaaatagaaa
    67261 aagaggtggc accatgattg aatttcaaaa tgtgtcaaaa atttataaag gtggaaaagt
    67321 cgctgtagag gacgtcaatc tttcatttga aaagggtgag ttcatttgtt ttatcggtac
    67381 gagcggaagc ggaaaaacga cgacgatgcg gatgatcaac cgaatgactg atccaacaca
    67441 agggaaaatt ttgattgatg gaaaatccat ccaagaaatt gatccagtgg aattgcgacg
    67501 tcagatcggc tatgttatcc aaagtattgg attgatgcct cacatgacga tccgtgaaaa
    67561 tatcactctt gtccaaaaat tgttgaaagt cagtcaagaa gaacggaata aaacagctga
    67621 aaaaatgatt gatcttgtgg aattgccccg tgagatgtta gatcgctacc cacatgaatt
    67681 atctggtggt cagcagcagc gtattggagt cgttcgtgcc cttgcagcga atcaagatat
    67741 catcttgatg gacgagccat tcggtgcgct tgatccaatc actcgtgatt ccttgcaaga
    67801 ccttgtcaaa gatttacaag agcgtttggg aaaaacgatc gtatttgtaa cccatgacat
    67861 ggatgaagcg attaaactag caagccgtat cgccatcatg agtgaaggcc gtgtgatcca
    67921 atttgataca ccagaaaata ttttacgtca tcctgcaaac gatttcgtag aagagttgat
    67981 tggagaagat cgcctactac aagccaagcc aaatgcgaca agagtcggcg aagttatgct
    68041 aaatacagca atcacgatta caccggaaaa atcattacaa gaagcaatca aactgatgag
    68101 ggaaaaacgt gtagatacgt tgttagttac cgataattcg aatgtattaa aaggatttat
    68161 cgatgtagaa acgttgaata aaaaacgagg aaaagtatcc agtgtcggcg acattttgaa
    68221 taaacatgtt ttttacgtaa aagaatccgc ctatcttcgt gataccttgc aacgcatttt
    68281 aaaacgcggg ctgaaatacg tgccggtcgt tgatgaacag aacaaagtcg taggtatcct
    68341 gactcgtgca tcattagtgg atatcgtcta cgatgtgatt tggggagaag atcccgcaac
    68401 tactgatgtt gcagagtcag ctactcctga agaatctaag gaggtctgac ctatgcagca
    68461 gttttttcat cagcacggtt cagaaattct ctcaaaaggt tttgaacatc tttatatttc
    68521 aggacttgct ttgatcattg gtatcatcat tgctgtaccg cttggtgtct tactgacacg
    68581 ttttccaaaa gctgccacga ttgtgattgg cttaaccagt gccttgcaga caatcccttc
    68641 tcttgcttta ttggcattga tgatcccgct atttggcgta ggtaaattac ctgcgattat
    68701 cgcactcttt atttattcat tattgccgat tttacgtaat acgtacattg ggatgaaaaa
    68761 tgtcgattgg aattatcggg atgtggcaaa aggcatgggg atgactgagt tccaatccat
    68821 tttttccgtt gaattgccca ttgctatgcc aacgatcatg gctggtattc gtttagctgc
    68881 cgtttacgtg attgcatggg ctacacttgc ctcttatatc ggcgctggtg gtttaggcga
    68941 tttgattttt agtggactga ataattacca accagatctc attttggcag gtacgatccc
    69001 tgtaacaatt ttagcactat tggctgattg gcttctaggt ctcttggaac accggctgac
    69061 accgatcgca cttagagagg agaatgaaga atgaaacgta tactaaaaat gaccatggtt
    69121 cttttctctc ttcttatact tgcgagttgt tccttccctg gtcttgccag caatacagat
    69181 gaagacacca tttcgatcac aggtggaatc acttcagaag cacagatctt agcaagtcta
    69241 gttgccggaa tggttgaaca ttatacagat aaaaataccg caatcatcaa caatctggct
    69301 actacaacta tcaaccatca agcgatgatg aacggagatg cttcaatttc agcggctcgc
    69361 tacacaggaa cagatttaac gactacattg aaccttcctc ctgaaaaaga tccgaaaaaa
    69421 gcgtttgcta ccgtgaaaga tgaatttgag aaaagatacg gtcaaacgtg gttcccgtcc
    69481 tatagttttg aaaatacgta tgtctttctt gttcgaaaag acaccgcaca aaaataccat
    69541 ctatctaaag tcagcgatct gaaaaatgta gcggatgaat tagtagctgg tgtagatact
    69601 tcttggatca atcgtaaagg agacggttat gacggcttcc aagaaactta tggcttctcc
    69661 ttcaattcga tattacctat gcagattgga cttgtttatg acgcagtcga agcaggaaaa
    69721 atggatattg ttcttggcta ctctacggat ggacggatcg ccagttatga tctagtcatg
    69781 ttggaagatg atcgtcaatt cttcccacca tatgatgctg ctccagttgt agacaacaag
    69841 atattagctg atacgcctca tttaaaagaa gccttaaata agttaggtca taccatcagt
    69901 acggaaaaaa tgcaggaatt gaactacgaa gcagataata atctagtgga accatcagta
    69961 gtagcacaac gtttcttaca agaaaaccac tattttgaag ggaagtgaag caattggata
    70021 aaatgaatgt ctttcaacaa tttttctatt atttccagga aaatggctcc tatatctttg
    70081 cacaatttat ccgtcacttc ctgatttcta tctatggtgt cctctttgca gcagttgtcg
    70141 ggattccggt tgggatcatg atttctagga gacgtaaatt agcaaactgg gtgattcgtt
    70201 tggcgaatat catccagacg atcccttctc tagccatgat ctccatttta atcattggat
    70261 taggcctggg agtcaatgtc gtgattgtta ctgtattttt gtattccctc ttaccgatca
    70321 tcaagaatac gtataccggg atgatccaag tagacaaaaa catccttgat gtcggcaaag
    70381 gcatggggat gactgctaga caacgactat tcatggtaga gttaccactc tctgtttctg
    70441 ttatcatggc aggcataaga aacgcgttag ttgttgccat cgggataacc gcgatcggtg
    70501 cattcgtcgg tgctggtggt cttggagata tcattatccg aggaaccaat gcaacagagg
    70561 gcacatcgat tattttagca ggtgcattgc caactgcatt aatggcgatc atcacggact
    70621 ggcttttagg tattttggaa agacggctag atccagccag ccgtacatca cgctgatgtt
    70681 attgtaaaaa acaaaagctt ctgcgaccat ttgttggtcg caaaggcttt tttagttctg
    70741 tcatttttaa ggcaataatc cactctgatt cttccctcct tatgggcaaa gagttgcttt
    70801 tcttagctat ttatccattc cgtatactcc aacttcatac tgccaacggg ttcatatctg
    70861 catccaccga ctaagttttt ttcttatccg ctaaggcatt ttgccaatcc attttcccat
    70921 cactcgtcat ggaattcata ccacatgatc tctaaatact cgtctgcttg ttctttgaat
    70981 tgggcatcaa ttcttacatc ctttggcgtg gctttcattt aagccttttc catcagtcct
    71041 cgattgttcg atgccttcag ctgcatcatc aaaactggtg actgccgtat cggtaacttc
    71101 gatcatcttt tatacaatcg ggaacttgcc atcctcatcc ttggctaaaa acatatctag
    71161 ccattccagc ttctcgccat gggaggtttg cggttcctaa aaccggtaca cgattcttat
    71221 ggactgcatc cgtcgcaact agacttggcg atacgatgat ccttcaccag aagagcaccc
    71281 ccgtaaacca attgatcgat atattgccaa taagaaaaga cattggcgta aaagatatcg
    71341 atccctcgtg atgcattgcc gttgatactg ctattcatgg ccgaaagcgc cacgacttta
    71401 acttcttccg tttgagtgac attcatgttc ggcaatgtcg ctttggatac ccgctctgct
    71461 aaaggaacga cactggtatt gtatttcgta tctgtatctt ttccaaaaga ccatgccaac
    71521 gaatcctctg ggaaccaata agacgactcc ggttgattgt ccattgcttt tttcaacata
    71581 cttttggctg tttctcgata aacgacattt ccaattgtct tcgcctcact ttggcgataa
    71641 tcgatggtcg ttgccactgc caacactaac aacgatgctc caattttact gattttcctt
    71701 gtcacacttc ttcctccttg ttttacataa acccgtcaac attccattcc taaactcaaa
    71761 caatgaccct tcaaaggtgg agatatagga acaaattaaa gaaatcatgc aataaatcca
    71821 agaaggttgg ttttagaaca aaaaaagagt ctcctttttg gggagactct ttgttaacta
    71881 tctaaaaagg ttggctcttc tcacttcact cataatgtgt ccaggcagaa taaatttcta
    71941 caactttatt ttcctcatca actttgtaaa ccactcgatg ctgtctattc agcctgcgtg
    72001 agtatctgcc ttcatgtgta ggtctcagct tttcaaaaga ctgcgtgggc atatatggat
    72061 cttccttcaa tgtctgaatc acttcttcaa attgtttctt taaattcgtt tgcttgattt
    72121 ttcttaaatc cactttcgca gagtttttga ttgcgactgt atagttactc atcaaagagc
    72181 ttcccaatca atatcatcga tattcgtaaa gctactgtcg tctttttcgc ggtctcgtac
    72241 tttatctaaa gtacctgttt gctcaagaaa aagggtttct tgaatcgctc tccagtcttc
    72301 cagcccaatc aatacagcat tgtttccact acgatcacta ataatctcga tttcagtatg
    72361 attttcattt acctctttca ataactgata aaaattttta cgagcagtgc taggattcat
    72421 cgttgtatta gccattgtct ctcctccttt ttctgatata attatagcgt acttgattaa
    72481 gtacgtcaaa aaaatacaat aaagcactta aattcagcaa acttttcctc ttttttacat
    72541 agagaaaaag accccttttt agggaggatc tttgtccacg ctcacttctt actcctttac
    72601 gactagcggt agccaaacgt aaagtaattg gtaacaacgt atcatcttta gcaaaggtcg
    72661 aatccaaagc ctgtgagtct atgcaacaac accaatacac gaaggttcct cgttgcagtg
    72721 tgacttgatt gatatcttga ataacctgag gatacgcacg aaagatttgt aacggttatt
    72781 caaaactgat tttggccgtc aagtcttcta ctgcctcaaa aatgattgcc tctttcgtct
    72841 cctgtcattc atgttcacta tcgatttgat acttgcttag accgttgggt ttgtgaatca
    72901 ccaattaaaa atggcactga gttatggtaa caaaaaatgg tcacttgacg aggctgagat
    72961 tcctacttat gaagacacat ggcacttaag agtcgaggta aaggaagaag ctgaaaatat
    73021 aggaggctgt acattatttg gcaaaggatt cggaaattat gatcaagaca tcaaaatcaa
    73081 aatgttttac agctaaatag gaagaataat aacatttcat acgctgttcc catctttaat
    73141 ggcttataga gggcaccttt agctgagaat aagacaaaac agaccctcta gcttcaatta
    73201 agagctagag ggtctgtttt tgattttaaa acttggttta tttcttcaaa tggtagctat
    73261 aggtgctgac aacgatattt tcacgccaag acaatcgcaa tcttaaccgc aaacttgttt
    73321 ggttatggag aatattctgc cagcgtctgt ttggtacaaa ttgaggaatc aacacagtag
    73381 ttgtatagtt ttgtttcgct gcatttttac ttacgatatc tacataacgg ataattggat
    73441 tttcaatcga gcgataagaa gagtggacga ttgaaaaacg gacatctggg aaatgctttt
    73501 taaattctgc ttcgatttct ttttcttttt cgacatcttc gtctagcgaa acatgcatcg
    73561 caacgacata atcaccgatc gaacgtgcgt aattcaacgc accgatattt acccgtgtca
    73621 cattcccgac taatacaaga acggtattcc cgtcataatc atgtagtttt gcatcatttt
    73681 ctaaacgaag ctgttctgct acttttttat aatgatcatg gatcttataa aaaatgaaca
    73741 taacgattgg cataatgatg aagaaaggcc aaatgtcccc taaccgatag acaaacaaaa
    73801 tcgcaatgat tgcatatgag atgaacgcac ccgtaatatt ggcaatcgat ttgcttaacc
    73861 atctttttcc ttcttttttc catttgacga ccatccctgt ttgagataaa gcaaatggaa
    73921 tgaacacgcc gatagagtat aacggaatca agcgttctgt tgagccatgg aaaataaaca
    73981 gcaatacgat cgaacctagc gctagtgtga taatcccatt ggaatagcct agtcgatccc
    74041 cacgatcttg atacatgtga ggcatgaatt tatcttttgc cagattgtat gcaagaactg
    74101 gaaaagcaga aaaaccggtg ttagcagcaa ctgctaaaat cagcgctgta gcaaattgaa
    74161 ggacgtaata caaaatacca tgtccaaaga cagctttacc aatttgagac aaaacagtga
    74221 cttctttttc aggaacgatc ccataccaat agttgataaa tgtgatcccc acgaagaaga
    74281 aacctaagat caatgccatc atcgtcaatg tagcagcggc attttttgct cttggcttct
    74341 taaagaatgg tacagcatta ctaatcgcct ccaccccagt taaagaggaa gaaccagaag
    74401 aaaatgctcg taaaatcaaa gcgatagaaa cacccggcac agccgctcct ggaagtgcag
    74461 tagcttgcaa tggcacagca cctgtcacga tattatataa accaacaacg atcagtaacg
    74521 agatcacaag gataaatgtg tacaccggaa ataataggaa cgatgcagat tccctcagcc
    74581 cacgaagatt cagcatcatc agtagcaaaa cgattgtcac agaaatagcg acttgatgac
    74641 cgtagagtgc tggcaccgct gatgtgatcg cttcagcacc tgctgagaca gatactgcta
    74701 ctgtcaacat gtagtcgatc aataaagagc caccggaaat caagccagca ttctttccaa
    74761 gattctcact gctgacgaca tatgctcccc cgccatgagg ataagcatgg atgatttgac
    74821 gatatgatag cgttaatgaa atcaataaaa taataacaaa agcggcaatg ggtagcgaat
    74881 accagatggc tgcagcagac aaagcgacta aaacgacaac gatttgttcc gtaccatatg
    74941 caatagatga taacgcatca gacgacaata atgccaaagc agcaaatcgg gttaatttgt
    75001 gctcatcatt ttcagcagat tttaaaggct tacctactaa caaccttttt aagtaatcca
    75061 atttctaaac tcctttacac acaattttac ttcaagtttt atagtcgaaa atttatagta
    75121 aacaagatgt tatagtacgc tcactgacct taaaagtcaa taaactttaa gaaaataatt
    75181 ggaaaaaaac agaaaaatat caagcgcttt ttcaaacgct ttaatacagc aaaaatctaa
    75241 cattttttta tgggcttttt ctttgaattc tataataaaa ggatagaact tgacttagaa
    75301 aatcaagttc tatccttttt gatatcttaa cttttggaag agagatgtaa ggctgctttc
    75361 tacccatcat tcttactact cgaagcatag cgcagttgtc acaacctctt gataaacggt
    75421 gtttaaaagc ttgcatctgc ggtaataagc ccaaccaaat taaaaacata agaagctgtt
    75481 tttatttggt cgttcttatt acttgatgca gagcagcttt tttacaacct cttggtacac
    75541 ggtgttcaat cagctgaccc tcggtattag ctcaaaaaaa cggcaaaata tgaggaacta
    75601 tttttccatt tttttctcta atactcaggt caaaacactg atttcacaac ctcttttttt
    75661 aatgaaaaat atggctctca tgcgccgctt ctttgaattt cgtcattttt tcttcgatga
    75721 acggatagat tgccgttcct acgattccaa agacaacaaa caaaccgatc atgatccaga
    75781 ttgctttcgt agcatttggc caataaattc ctcctgcaga ttcccgtaac aagtttaccg
    75841 catgagtaaa tggcaagaac ggattgatca tttggaagaa tttccctgag acttggatcg
    75901 gatagttccc gcctccgcca gagatcgaca gtactaagat gataatagcg atccctttac
    75961 cgacattatc gaataatgca gccaagacat agacgatcat catgaacgct aaggcgatca
    76021 agacagcaaa tgacacgctg tagaccggat tttggacatc tactcctagt aagaaaatat
    76081 tccctaatgt aacgatcaag ctttgcgcaa tcgccattgt caaaaatgtc agcatacgag
    76141 caacgaattg ttctcgtttc gtaaaattgt ttcggtcttt ctttcctaaa tagtattctg
    76201 tcgtagcaac acttgaaaga agaacagcgc cgacccacag acatagtgca gtataaaacg
    76261 gggtgctagc tgaaccgtta tttgcgattg gataaagcgc attggtttgt agctcaacag
    76321 gttgtgtaaa gaagtcactt tcttttgttg cgtctagttt caataatttg atgacttcgc
    76381 ctagatcgac ttcttgttcg ccttttcgga tcgcgtctgc tgctttttgg ataccagctt
    76441 tgatatttgg ccagtcattg ttgatcaagt ccgcagcagc gttcacagct gtttcgactt
    76501 ctggcatttt ttcatttact gttgtcaatg taccggtgat ttcatttttt agtgctggcc
    76561 aatcattttg gataaaatca gcggccaatc ctaatttttg ctgaatgatc ggtaattcat
    76621 tgttgtatag gtctgcccct tcattgatgc cattgacgat ggtatccata tttccattca
    76681 gcattgtatt ggcatcatgg atttcttgtc caattgcagg catttctttt tgatattttt
    76741 ctaaaattgc cactgcattc gttacagttg ctttcgttga gctgagaagc gaatcaaagt
    76801 cgatctggtc cgctttgctc agtgcgcctt gtgcagtccc aatcgtatcg atgacttggt
    76861 ctagtagaga agtgacagtg gaactgattt gacctgtatt gataccagca atgatgccat
    76921 tgatattatt aacaacggca tcaatttgat ctagcaattc atcaatagcc ttcgtgtctt
    76981 cattttgaac agctgtgttc aaagcagata ggcggttttg cagattgctt agcaagggtt
    77041 ttaattgatt tagctgatca ataattggct gtaatttcgt atttccagca cttgtttgca
    77101 atttagtcag gaactcgacc agtttatcga ttgcattttg ttgttgagat attccgtcaa
    77161 taaagccgtt caatacattg ctgatgtttt tcttttcatc atcagtcagc ttaccatctt
    77221 caatagctgt tcttacagta tctattaacg aacctgtcgt tgttgccact tgtccaattg
    77281 acttcaatgt aacatctaca ctgtttgtga tgcttggtat cgcatctttc agctgagagg
    77341 cacctgattt tgtttggttt gctagatcac ttgcctgatt ttctaaattt ttcacatctg
    77401 gcaagatatc ttgtacttgt tggatgatcg tcaagccttg ttttgcttca tcgattcctt
    77461 ggttcattgt ctcttggatc gaagcaaaat cgccgtcgat ctctgctagt tgcttaccgg
    77521 cattttggat ctctgggatt ttttcttgca aatcaaggat gatttttgct tgatctttca
    77581 actcaggcat tttgtcattc aatgcaacga ctttttcacc catctcatct actttaggga
    77641 tgtaatccac gaattcattt gctttattca gtttttcctt gatttcaggt agttgacttt
    77701 gtaattcgag gacttgtttt gtgtagccgt cgatcgtgtc caaattttca tctgttgata
    77761 aaatcatatc tttaacttta ttgatactta ctaggttcgt atcgatgtcg taacctatct
    77821 cattgaatac tttcaataaa gtcgaactgg ctgttttgat aaattcattt gtgatttgcg
    77881 attggatcga acttgctcct ttatcggtga ttttcggtgc aatcgcattg attttttcat
    77941 ttaccgtata ttcgattttt ggtttcttga tatcaccact agtaaaactc agcagatctt
    78001 ctgagaaatc ctttggcaag taaatacctg cgtaatactt tccggaacgg actccgtctt
    78061 ctaattgttc ttttgaatca acgaattgcc atcctaattg tttattttta tgaagcgatt
    78121 cgatgacttg ctccccaatg gccacttctt taccttgaaa ctctgctggc ttgtctgcac
    78181 tgtaaacagc aattggcagc tctccagtat ttccatatgg atcccataat gctttgatgt
    78241 taaaccacgc atatagcgaa gggatgatca tgatcgcgat gatcagaagt gttgcaatcg
    78301 ggtttttgaa aatccgtttc cagtcaagca aatataatcg aagcgtattt ttgattgact
    78361 gcatagttct cccccttctt cttttttcag ctgaattact ttaccatgta tttcatactt
    78421 ttttcaatcg gcttttttca aaaaagtcga atttttggac atatcacggc aattgtctca
    78481 ttgtaatctc ttacatattg agaaataatt aaggattaca gcctttactt tatcatgaaa
    78541 taaaagggaa agataatttt atgccaaagt ttttatctat tatacgtata cgcaaaaaag
    78601 ctaaaacatt ttttgtcttt gcccctacaa aaatgtttca gcttttttcg ttttttattc
    78661 ctgtatttct tatttttcga atgacaggat gattttccca gcaggaggat gtccttcaac
    78721 tagctgatgt gcttggatga catgcttaag tgaagcagac agattcattg aaataaaaac
    78781 atgaaaggct cctttttggt aggctttgat tatgccagca aaggcttctg catctagata
    78841 ttcctttctt ggaacaaacg attcataaaa gccttccttt ttttgccgca aatctagatc
    78901 tgggaggtca tttaatgcaa catacctgcc gcctggtttc atgatctgga tgccggtttc
    78961 tcctttgata cttcctttcg tcgcatcgat tacaaggtct gcctgatcag caaattgcag
    79021 acctggattt gttttatcat aagcagcaaa tgctgaagct cctaattttt ttaccttttc
    79081 ctcattttta ctggatgcac tggttaagat tcggattccc ttttcatgga gaagctggat
    79141 cagacttgac ccgaccgcac ctgatgctcc tagtatcatt acagtatctg tcggctggat
    79201 ttccgtcaaa tggttgatta gattataagc cgtaattcct ggcgtgacca ttccggctgc
    79261 ttcttcccaa ctcattttat ctggaatttt tgctactttt gctgatggca acacgacttc
    79321 ttctccgtaa gtcccgccga ctgcatggac agctactcga tcacctacat gaacagttgt
    79381 gacatctgaa ccaatctctg tcacaatacc agcgccatca ttacctggta cataagggaa
    79441 tttcaatgtt cgtatctctt tcatttctcc taaacgcaag gcaacatcat aaggattcac
    79501 actgaatgct tttatttcta cacgaacatg tccagaaccg acttctctgg gatgagcatc
    79561 gatttcttca aaaacatctt gtgcttctcc gtaaccgtta attgcaaatc ttcgcatggt
    79621 caccatctcc ctttttcttt aagtttacgt ttatgccttt attttgacaa aaaaaatgtc
    79681 ttttcgtttt ggcgcatgat tcaaaacaaa atagttgtct tttttcgcgt aacgtgttaa
    79741 attatttatc taaaagcgta aagattacga tttacgctaa taaaaaataa ttggaggaat
    79801 ttgttgatgg ctaaaaaatc aaagattgcc aaagcaaaaa aacagcaaga aacgattgaa
    79861 cgctatgctg ctttacgcca ggaattaaaa gcgcaaaaag attacgaagg cttgcgtaaa
    79921 cttcctttag atgctcgtcc agaacgattg aaaaatcgtg atttaatcga tggacgccct
    79981 cgcggataca tgcgtaaatt cgggatgtcc cgtataaaat tccgtgaatt agcacataaa
    80041 ggtttgattc caggagtaaa aaaagccagc tggtaatcca agtctggctg taatgtaaag
    80101 gaggagggcg catggaccac tccttggatc atcaaaaaag atacgttcgc ttcttctagc
    80161 agaaatgctg gtactagaag cagacgtatc tttttttacg cacagctggt ccttttttat
    80221 atgtaaaggc tgcatggtta cttcgctata tttatttagt aacaggagtc agtgcttcga
    80281 tacccacact aattttcaat gctcggtcaa cttctgccat aatgggtcga tccaaatggc
    80341 agaccttttc tttcaatctt gatttatcga tcgttctgat ctgctccaac aggataacgg
    80401 agtctctttc tattcctgtt ccagtagctt tgatcccaat gtgagtcgga agcttaggtt
    80461 tagccatttt tgccgttatg gccgcaacaa tgatcgtcgg gctaaaatgg ttacctagat
    80521 tattttgaat aaccaaaact gggcgtgttc cgccttgctc cgatcccacg actggagaaa
    80581 gatcagcaaa ataaatatct cctcttttta ccataggatc ctccttattc ttgatattct
    80641 cttggtatcc gctgtcctaa tccgcaagcc acttcatagt ggatcgtacc taattgatct
    80701 gctatatcct gcatagtgat ttctttgtct gcatttttgc cgataagcgt cacttttgtt
    80761 ccgacaggaa attcttgagg caatcggatc atcagttgat ccatacatac acgcccaatc
    80821 gtttcacagt agttcccttc taccaataga gaaaaaccct gcatctttcg tggccagcca
    80881 tctgcataac cgatcggtat cgttccgatc cactctgctt caggagtgat atatgtttct
    80941 ccatagccga ttccttcacc tgctgggagt tttttgactt gaatcaattc agaaaccagc
    81001 tcaagtgctg gctgcaatgg ataaacttcc ggtagtgcgt gcccagaggg attaagtccg
    81061 tacattgcta ctccataacg aatcatattg ccgattgttt catcatgcca taaagccgtt
    81121 gcactattgc tgacatgtac atatcgagga agttcgggaa gttttttcag cacttctata
    81181 aagcgttctt tttgcagatt ccaatatgta tcatctgcct gatctgctgt agaaaaatgg
    81241 gtaaataaac cttcccattc taatacacga ctttctttga tgaatgcagc tgcctctttt
    81301 acttcttcag gtgtacaaaa tccgatacga cccatcccag tgtctgcttt tagatgaatc
    81361 gaaagaggcg tctctagctt acttttctct aaaacagcag ctgctgcttg caaccattcc
    81421 cgtgtacctg cagttactga taaatcatga gcaacagcta cagtcagtgc gtcgtaagga
    81481 accatattca agataaggat gggctgagta aatccagctt ctctcaactc gactccttca
    81541 tctaaatttg aaacacaaaa gcccgaagct ccacctgcaa ctgctgcctc agctgtttca
    81601 atagctccat gaccgtatcc gttcgctttt actactgcaa acaattcttt tccttgcgga
    81661 agtcttgcaa cttcatttgc tacattttca gttatagctt ttttatgtat cactgctttc
    81721 gttgggcggt gccaagcgac aaccatcgtt tttccttctt tctagtcttc caaaataatt
    81781 tgtgcaaaag ctgtttcatt tgtatgagta atactgaccc atacattgcc ttcatgaggt
    81841 gaacgcgtca caacaggctg accattttca ttttttaaaa tctcgacatc ttgaaaggta
    81901 acttttccga tcccagttcc ccaagcttta gagaaagcct ctttgcaagc gtaacgcccg
    81961 cctaaaaatt ctacttggcg atgaaaaggc aaggactgga atagtttcat ttcatcagag
    82021 gtcaagattc gtgcaatgaa ttttggtttt tcttcgatca gccgagtgat cctaggaagt
    82081 tcgactgcat cgatcccaat tccttttatc atatgctttt ctcttttcaa taaatttaga
    82141 acactctcat tctaccaaat tataaccatt ttgccacaaa taagtccaca aataacaaaa
    82201 atgaaagttt ctcttaaaaa agagaaactt tcattttatg tttaatcgtt atttgaacgg
    82261 attacaaatc cgcgtttttt atcattgtga cgtttaccgc catctttttg gctgttatta
    82321 tttttgctat aaccgccttt tgatttgttt ccacgataat taccgccgtc acgacgatta
    82381 cggttgtttc cgccaccacg tttgccattt ttattgtatc cttttttctg cattggcaat
    82441 gggcgttctg gtgtgatctt cactggcact gcatcagctg gatcttttgc tgtcgttttt
    82501 agcaaaagtg caactaaatc ttgtgcagaa tattcttcta ataatttatc tgctgtttgc
    82561 aggtatttat ctagaccatt ttctgcaagt tttgtttcga tttgttcaac tgcagcacct
    82621 aattgacctt tgaatgcttc tttttcggtt ggtggacgta aagtcgtcat ccgttttttc
    82681 gtcaagtttt caatcacatg caagtagtcc atttcatttg gtgtaacgaa agtcacagac
    82741 ataccgcctt ttccggcacg gcctgtacgt ccgatacggt gaacgtagct ttctggatct
    82801 tgagggatat catagttgta cacatgagtg acacctgaaa tatctaatcc acgtgcagca
    82861 acgtctgtcg ctacaaggat atctaaatga ccgctcttaa atgaacgcaa tacgctcatt
    82921 cgtttttgtt gagacaaatc gccatggatt ccttctgcac ggtaaccgcg tgcttctaat
    82981 ccgcgtgcca attcgtctac acggcgtttt gtacgtccga agacgattgt taattcaggt
    83041 gtttgaacat caaacaagcg agtcatgata tcgaattttt cgtattcttt tgcgcggaca
    83101 tagtattgat cgatcaagtc agctgtcatt tctttcgctt tgatcttcac atgatgtgga
    83161 tttttcatga atttaacgcc aatattcttg atagctggcg gcatcgttgc tgagaaaagt
    83221 aatgtttgtc tttgatcagg aacttgtgaa atgatttttt cgatatcttc caagaagccc
    83281 atattcaaca tttcatctgc ttcatccaaa actaatgttt gaacggttcc aagtttcaat
    83341 gtgtggcggt taatgtggtc aagcatacgt cctggtgtac ccacaacgat atgtggacga
    83401 tctttcaagc cacggatctg acggccaata tctgctccgc cgtaaacggc ttgtacacgt
    83461 acttttttgt cgcgccctaa acgatataat tcttcttgtg tttggatagc taattcacgt
    83521 gttggtgcga taactaaacc ttgtaattcg tgacgatctg gatcgatttt ttctaacatt
    83581 ggtaatccaa atgcagctgt tttccctgta cctgtctgtg cttgtccaat aacgtctttt
    83641 ccagctaatg ctagtggaat cgtttctgct tggataggcg ttgcttcttc aaaaccagcg
    83701 cgttcgactg atttcaacaa ttctggtgat aattctagtt ctttaaattt caaatgaatc
    83761 ctcctatatg gttgttaact gaggatgtag cttttttgct accccgtcga tttgttcggt
    83821 caaagtgtat tgtttctttt tgacagtggc cacgcacgtt tttatccatt cttagcccct
    83881 gtggcaccac cgaaaaatca ctttgcgaag tttaggcatt agaaaagcca aacgggtcgc
    83941 gttcagcttt atcattatta tgacatctgg cttcaacaag ttgtttctat ggcaaaacca
    84001 gtccaatttc tcttcatctt tcggcaatag gttattctaa catagttttt cgttttctgc
    84061 aagtttacag atttttattt catttgctga agttgttcta ccacttcaaa taagcccatg
    84121 ctgttgctgc cttttagcat aatactatct gttgcttcaa gattttgttt gatagcatca
    84181 atcaatttat tcttttcttt ttcaaaatag aacacaggta gttgggggta tttttggttc
    84241 aattcttctt ttagtgcatg catttgttcc ccataaagga aaatcatggc gaatttctca
    84301 ggatcgatat gttcactcat ttgcgcatgc atatttaaag actctttccc taattccagc
    84361 atatctgcta acacagcgat tctgcgtcct tttgttggca gatttttaaa agtatctaat
    84421 accagtccca tggctgttgg atttgcattg tagacatcgc tcaaaatagc tgcaccattt
    84481 cctgccgtta gccattcggt tctgttttga gtgatagaaa catgggcgag cccttggcgt
    84541 atctcaggta tggacagtcc aaagaagcgc ccgatcgtat acgcaatcaa agcattcgtt
    84601 acattataac ttccaggcag cgggatcgta aatgtttctc cttctactac aaaatcggtt
    84661 tgtgcttttc cttttgctgt cacttccgca tgaacatcgc catttccaat accgaatgtt
    84721 gtgactgttt gtactaatgt tgccgttaaa ggtgtcagca acggttcatc tgcgggcaca
    84781 acgagtaatc cgtctgatac aagtccgtca gtgatttcca ttttggcttt agcgattcct
    84841 tctcgcgacc caagattttc tatgtgtgct tcaccgatca ttgtgattgc tgcagctttt
    84901 ggttgagcca taagtgaaag ttccgtgatt tcattggcgt gatccatgcc catttccaaa
    84961 acgatctttt ctgtatcttg gggcatgtgc aaaatcgtgt aaggaagacc aatattattg
    85021 ttgtaatttc cttgcgtctt atatgttttg tatttttcag acaagacaga cgcggttaga
    85081 tctttcgtgg tggttttacc attgcttcct gtaattgcaa cgacttctgc gcctactttt
    85141 tccaagtaat aggttgccaa ttgctgcatg gctttcaaag gatctgctac aggaataact
    85201 ggaaaatttt ttggagcttg ttcaacaggc aagctccaaa atgaagcaga tgctccgttt
    85261 gtgatcgctt gctggataaa ttcatgtcca tctcgcgtac cagcaagagg aacgaataaa
    85321 cttccttcgg ttatcttccg gctgtcaaat tcgacattgg taatctttgt cagtgcagag
    85381 cattcgctgc ccacggcttg tgcaatttct tgtattgtta gattcattga gatctctcct
    85441 aaaaaaggtt gtgaaaaaag cgtttggcct aaacggcggg ttcgcatgac tctcacttcc
    85501 aagtaaattt ctctattcgt atttagaagc tagaatgaac gcggttacgc aatcactcca
    85561 gcctcttctt tatttctctt tattcatttt tttcaaaaaa agattgacgc tgatggtatc
    85621 gattcattcc taactggatc agttcttcaa tcaaatcacc gtatttcaag cccatatttt
    85681 cccataagag tgggtacata ctgaactccg taaatcctgg catagagttt aattcattca
    85741 ggaataattc atttttattt gtcaaaaaga aatcgcaccg gctcaatccg cttccaccta
    85801 acatcgtgta agctaacttc gcgtactctt gcgctttttg ataaacttct tctggcactt
    85861 cggctggaat ctgcatttcg attttattat tgatatattt tgcttcataa tcatagaatg
    85921 ctacgtcttt tacgacttca ccaggcaaag tcgtccgaac gtcttcattt cctaatacag
    85981 caacttcgat ttcgcgcgct tcaattcctt gttcaacgat tgctcgagaa tcatactgat
    86041 aggctgttgc taaagcattt tgcagctctt ctcggttttc tgcttttgta atgccgacac
    86101 tagaacccat attcgccggt ttgacaaaca tcggataaag caaagaacct tcacattgat
    86161 caaatacttt tttaggattt tctttccatt gattcttaag tactggtaca taaggaactt
    86221 gcggcacacc agcagcttgt aaaatatact tggtcatgat tttatccatg gcacatgcac
    86281 tggtcaatac gcctgcgccg acataaggca tattcaatgt ctctaagaag ccttggatcg
    86341 ttccatcttc cccgtttggc ccatgtaaaa ctggaaaaac gatggctcct tcttctttga
    86401 tttcgcccgg attgatcact tttcctgtaa agccttcctc tgtctgtcca cttgggtccc
    86461 atgaaagatg caagacatct ttgctggcag gtttttctgt tagtaatgga cctttgaccc
    86521 attgtccttc ttttgtaata aatacgagtt gaacttggta ataattataa taaatggcat
    86581 ttaaaactga aaatgcggaa agaatggaca cttcatgctc tgcgctgcgt ccgccatata
    86641 gtaaagtaat cttcaaaaga ttgtcctcct gtattctaaa tcgttcagtg atttactctc
    86701 atattttagc acaaaacaaa aataaacgaa taacttattt ataaaaaaac gagccagctt
    86761 ctaaaagaac gagcgtcatt tattttttgt cagctagatt atttgtcccg ttttttataa
    86821 aaagttatga taaagaaaag gagggatgat gatggcgcaa acaaatccac gcagccgctt
    86881 ggcagaaatc attcgagtgt tcatcaatta caatgtagtg ccaaactttg tacagcaaaa
    86941 aaatcccgaa caggtaaaaa aagcctttga agaactaggc cccaccttca tcaagatagg
    87001 acagatgctt tctgttcgag aagatttgct ttcttctgcc ttcactcaaa cattcaaaac
    87061 attacaagat agtgtaccta gcgacacatt ttcaacggtc aaaaagacga tcgaaacaga
    87121 actttctctt tcattatcag atatattcga tgatttttca aaatcgcctt ttgcctctgc
    87181 ttctatgggg caggctcatc gtgccaagct gaagaacggt gacgcggtag tcgttaagat
    87241 ccaacaccct aacatcgccg aagagatccg acttgatctt caactatttg aacgagcgat
    87301 ccctttgatc aaatacattc ctgaaactag cgtagttgat ctaaaagggg tactccaaga
    87361 agtaaaacgt tccttgatca atgaaatgga cttcttaaaa gaaagtcaaa atggcgaaca
    87421 attctatcaa aagaacaatg gctggaaaga gatccgcagc cccaagattt atgacgcttt
    87481 ttgttcgaaa aaagtgatcg tgatggaaga aatgtctggt aaaaacttga atcatttaat
    87541 gaacgccgaa aacaaaactg aaacttttat cactggaatt caaaacaagc agctgaaaca
    87601 agaagttgca aagcttttag ttgagaactt tatgaaacag gtgtttgatg atggtttttt
    87661 ccatgctgat cctcatccag ggaatctgct attccatgta ctaacaaaag aagaacagac
    87721 acaagctagc cgaaaaactg aaacagtcca tgaaaaagag ttcggttcct ttgcttttcg
    87781 agcctccact tctgcagaag accctgttgc gccatatacc atcaactaca tcgattttgg
    87841 tatgatgggg catctttctg caggacttag gcaaaaactc acacaagccg ttttagcgct
    87901 gtatacgaaa gatgcttatc gaatcgaaaa agcggtcctt cgactttgtc agcaagaagg
    87961 ctcgtttgat gaaagtcggt tccaccaaga actgacaagt tttcttgaac agtattatga
    88021 ttctcctatt gatgaaatca acttgcaaga agtattcaca catgtcgtga cgatttgtca
    88081 tcaaaataat ctgcagttcg atcgtgatat cacgcttttg ctgaaagcat ttgggacatt
    88141 agaaggggtg atccgcgtcc tcgatcctga agtttccctc atggaagtcg cttcgccttt
    88201 tgctcaacat tattttctca ctcatctgga tgtagaagat acattgaaac aaagcggatt
    88261 agacttattg gaagggatga aggctgcgcc taagatccct caacagctcc accatctatt
    88321 agaaatgtgg acttcgggac aaggaaaagt caatttggaa ttgaaaaagc aagacaaatt
    88381 attgagcagg atcgaaagta tgatcaatcg gcttgttttc ggtatgattt tagctgcatt
    88441 gatcgtaggg tcctccctgc ttgtccaagc agcacctgta gaaaacgcag aggtcgtttc
    88501 cttattaggg atatttacgt atgctattgc cgcattcgtc attatttttt tggcaatcga
    88561 tgcattgatc caaatgtata agaagaggaa aaagtagaaa aaggttgtga cagaaagaat
    88621 cagcttcaag aaataagaag gggttttaca taaattgttt ctcaaatttt tgtgaaaatt
    88681 cggcttattt ttcgaagagg ctacttctga aacaccgaga ataaaaaatg tgaaaaagct
    88741 gttctgcacc cagtaataag aacaatcaaa aagggaacat ggaacacatt tatcctgttt
    88801 ccctgttccc tttttgatgt attcgagcat aaataaaata ccttcgttac ctactatctt
    88861 ctgtacttgg taaaccttag tcaattgcct tttttaacgc ttgacgaaaa gacatatgat
    88921 ctttctccgt aaagggtttt ggaccctttg tccttatgcc agcttttctt aactttccac
    88981 tatgataacg ttgttctaga agcgtgccga tattcgcttc gtcaaattct tttccagagt
    89041 gatggaacac tcgcacaccc ttcggcaata caagtgaagc taaaccataa tcttgcgtga
    89101 tcaaaaagtc attcttctta accataccga cgattttata atccgcacta tcagctccgc
    89161 ggtctacgta gacgatttgg acatgattag cgtattcttt ggtcgtataa tggtccacac
    89221 tggtcacgat aaccacgtca agaccatagg attctcctaa ttttatgaca tcttctttta
    89281 ctggagaacc atctccatca atgaatagcc tcattctttt tcgccttctt ccataaatga
    89341 taaacagtta ctaatccgct cagtaaaaga ccaacattga tccattttgc caagataagc
    89401 agttgtacac tttctatcgg cactgattca tggttcagcg tgatcaataa tagatggatt
    89461 ggctctccca tttcttttgc taaaacaaac aaaagcgtca tcaataaaaa ctggtggatc
    89521 acactccctt tattttgagt agtatacttg acaacgatcc ggcgatccat tggaatagct
    89581 gtatcagttt gataatattc cttatttagc cagctgcctg ttactacgtg ccagaaacta
    89641 agcagaaaga cacctatcgc aaaaccattt ggaatcaaga ggaccaataa agaagaactc
    89701 agtccaagca attgcatagc caatggagac catgttaaac gtttcaaaat ccatggtccg
    89761 actatttttg ctgcaatcaa gcctgctgca taaggcaaat acataaaaat cgaaagtttt
    89821 tctaatccgt acagtatgcc aacataaaaa ctgctaaata aaaaaaggaa attccctagc
    89881 attccattta gaaaagtaaa cagatttagc cagcttggca acttccattc cttcttctgg
    89941 tgtcctaaaa caaacacgaa caagatgaac agcagcaaga aaccataaat agcaagatca
    90001 aaaagccttt catcgaataa caatcgggca tttctcaaaa gaaacaataa gccaaagaat
    90061 atcaaaaata aaacaagctc tcgcgtagct accagatttc ttttgatgtc tttgaaatcc
    90121 agttcgtaac gcggataatg actaaccgta tggtaggcca tgacgtaaaa aagtgtataa
    90181 atagtaaagc ttgctgcaat ctgagtcggt gcaggcaact caatcgcttg atacaggaga
    90241 aatagccaga tagctgcaaa taagtacttt ttcccatcca tattgataaa accttgcgtc
    90301 ttttcgtgaa aattgaccgt ggtattagca ggtacaagcc atgctgcact cagccctagc
    90361 aaaacacttg aaaaataaaa taaaggaaaa taaaatacgc ctaatattcc aagcaatgaa
    90421 ccagcaccac caatcagcag agcgatcatc agcaacgtgt aactatctag accaaatcgt
    90481 agactgttga ctaaaaatag tccagtcatc cgaaaggcat aaaacagcgt aaatggcaaa
    90541 atcgtcagcc aattatgcga gtctgttagt cccaaaaata aaagataagg aataaaaata
    90601 accgtgttac ttaagataaa gggcgttgtt tgtgtaaaat tacgcccaaa tcgtttgagt
    90661 ttttcgaaca tgacaatggc tccttaaaca gtcttataac taatctgctc ttcgatttta
    90721 gcattaaagg ggaaataaac caattttaca gaatatattc ttgtaaaaaa aaatacagaa
    90781 agaagcataa gcttctttct gcatttttac ggtacttgat tactcaagca gacaagccct
    90841 tctccacaaa agtcttgccc gacacccctg catccggcag gtgataaaga tagaaatcaa
    90901 ttatcctgtg cctccaaaat caattaggag ctctgtaaac cagagtcctt ctcgacccgt
    90961 cgcataaatt tactttaaca cagttcctat gtttatgcga gagctttttt cattttataa
    91021 tcgaccattt gaaatccttg accgatatct gaaataagtt cttctgtaat ctcaaatcct
    91081 tcatgcttat aaacctcgat tgcttgatga ttcccctgat tcactcgcaa aaagatctct
    91141 ctttcctttg tttgcgcagc aagttcttca taccagcgaa aaactgaaga agtcaatcct
    91201 tgaccacgta ctttatttag caaatataat ttacttaaat aaatttttcc atttatctct
    91261 tcataagcag tgtaaccgac agtcttttct tcgcttttta ataaaaagta ggacacacct
    91321 tctgtcagtt ctttttgaat ctgttttttt gactgataag ttttcagcat gtaatccact
    91381 tgtttttgac caatgatcgg cacaaaaact tccggccata cttcttgtat gactgccatc
    91441 agctcatcca gttcattttc tgttactttt attttttcca tacacccacg tcctttttta
    91501 cattataaat gaccttgcgc ttgatggaat aaaaagagca tgatcatgct atacacaccc
    91561 accgaccacg gtttcaagaa aatcacaatc tgcataaatt ccctaaaaga taatttcgtc
    91621 aaaccagcta ctagacagat caagtcgtct ggcgcaaagg gaagcagcaa ggtaacaact
    91681 agtacttttt taatatcttt cgtttttctt gtcagcaatt catcaaattt ctgatacttt
    91741 tttggcgata aaataagctg gacaaaggct acgccatagt aacggacaag caaaaatccg
    91801 attgcttccc caatcactag gccaatacaa ctatataaaa gcccaaatcc attgccaaac
    91861 atcagcatgc ccgctactga ggagatccct cccggcaaaa taggaatgat cacttggatc
    91921 acttgcaaca gaacaaatat catcactgca tacttgccaa attgctggat aaacgcttgc
    91981 aaagacgtgc tcgatcgaaa aatcccatga tgataagcat aaagaatcaa cacaaagaaa
    92041 aaaaacagac caataatggg catgatctga agacattttt gtaaaactga tcctttttta
    92101 gacatctata ttccccacat cttttttcat ttattaaaac tgcctcct
//
LOCUS       DAZKCW010000002        90801 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000002 DAZKCW010000000
VERSION     DAZKCW010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 90801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.002"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..590
                     /locus_tag="ACG84Z_000088"
     CDS             <1..590
                     /locus_tag="ACG84Z_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9160971.1"
                     /translation="FLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYF
                     GNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLI
                     VGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMA
                     VKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(830..913)
                     /locus_tag="ACG84Z_000089"
     tRNA            complement(830..913)
                     /locus_tag="ACG84Z_000089"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(877..879),aa:Leu,seq:gag)
     gene            986..1147
                     /locus_tag="ACG84Z_000090"
     CDS             986..1147
                     /locus_tag="ACG84Z_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9160972.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            1296..2513
                     /locus_tag="ACG84Z_000091"
     CDS             1296..2513
                     /locus_tag="ACG84Z_000091"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFP9160973.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2697..3533
                     /locus_tag="ACG84Z_000092"
     CDS             2697..3533
                     /locus_tag="ACG84Z_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9160974.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            3609..4757
                     /gene="nagA"
                     /locus_tag="ACG84Z_000093"
     CDS             3609..4757
                     /gene="nagA"
                     /locus_tag="ACG84Z_000093"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFP9160975.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            5035..6036
                     /locus_tag="ACG84Z_000094"
     CDS             5035..6036
                     /locus_tag="ACG84Z_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFP9160976.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            6055..7074
                     /locus_tag="ACG84Z_000095"
     CDS             6055..7074
                     /locus_tag="ACG84Z_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFP9160977.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(7176..7892)
                     /locus_tag="ACG84Z_000096"
     CDS             complement(7176..7892)
                     /locus_tag="ACG84Z_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFP9160978.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7861..8646)
                     /locus_tag="ACG84Z_000097"
     CDS             complement(7861..8646)
                     /locus_tag="ACG84Z_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9160979.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8637..9386)
                     /locus_tag="ACG84Z_000098"
     CDS             complement(8637..9386)
                     /locus_tag="ACG84Z_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFP9160980.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9684..10208
                     /locus_tag="ACG84Z_000099"
     CDS             9684..10208
                     /locus_tag="ACG84Z_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFP9160981.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10224..11723
                     /locus_tag="ACG84Z_000100"
     CDS             10224..11723
                     /locus_tag="ACG84Z_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFP9160982.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11811..12413)
                     /locus_tag="ACG84Z_000101"
     CDS             complement(11811..12413)
                     /locus_tag="ACG84Z_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFP9160983.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            12517..13473
                     /locus_tag="ACG84Z_000102"
     CDS             12517..13473
                     /locus_tag="ACG84Z_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFP9160984.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13778..14734)
                     /locus_tag="ACG84Z_000103"
     CDS             complement(13778..14734)
                     /locus_tag="ACG84Z_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9160985.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14908..15468
                     /locus_tag="ACG84Z_000104"
     CDS             14908..15468
                     /locus_tag="ACG84Z_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9160986.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15461..16285
                     /locus_tag="ACG84Z_000105"
     CDS             15461..16285
                     /locus_tag="ACG84Z_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFP9160987.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16295..16912
                     /locus_tag="ACG84Z_000106"
     CDS             16295..16912
                     /locus_tag="ACG84Z_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFP9160988.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16930..17613
                     /locus_tag="ACG84Z_000107"
     CDS             16930..17613
                     /locus_tag="ACG84Z_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFP9160989.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18296..19579
                     /locus_tag="ACG84Z_000108"
     CDS             18296..19579
                     /locus_tag="ACG84Z_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9160990.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            19595..20482
                     /locus_tag="ACG84Z_000109"
     CDS             19595..20482
                     /locus_tag="ACG84Z_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9160991.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20499..21335
                     /locus_tag="ACG84Z_000110"
     CDS             20499..21335
                     /locus_tag="ACG84Z_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9160992.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21338..21961
                     /locus_tag="ACG84Z_000111"
     CDS             21338..21961
                     /locus_tag="ACG84Z_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9160993.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21958..23250
                     /locus_tag="ACG84Z_000112"
     CDS             21958..23250
                     /locus_tag="ACG84Z_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9160994.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      23609..23706
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23822..24403
                     /locus_tag="ACG84Z_000113"
     CDS             23822..24403
                     /locus_tag="ACG84Z_000113"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFP9160995.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24406..25713
                     /locus_tag="ACG84Z_000114"
     CDS             24406..25713
                     /locus_tag="ACG84Z_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFP9160996.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26129..26617
                     /gene="purE"
                     /locus_tag="ACG84Z_000115"
     CDS             26129..26617
                     /gene="purE"
                     /locus_tag="ACG84Z_000115"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFP9160997.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            26610..27734
                     /gene="purK"
                     /locus_tag="ACG84Z_000116"
     CDS             26610..27734
                     /gene="purK"
                     /locus_tag="ACG84Z_000116"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFP9160998.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27747..29042
                     /gene="purB"
                     /locus_tag="ACG84Z_000117"
     CDS             27747..29042
                     /gene="purB"
                     /locus_tag="ACG84Z_000117"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFP9160999.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29222..29599)
                     /locus_tag="ACG84Z_000118"
     CDS             complement(29222..29599)
                     /locus_tag="ACG84Z_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161000.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29855..30583
                     /gene="purC"
                     /locus_tag="ACG84Z_000119"
     CDS             29855..30583
                     /gene="purC"
                     /locus_tag="ACG84Z_000119"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFP9161001.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            30583..30837
                     /gene="purS"
                     /locus_tag="ACG84Z_000120"
     CDS             30583..30837
                     /gene="purS"
                     /locus_tag="ACG84Z_000120"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFP9161002.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30839..31510
                     /gene="purQ"
                     /locus_tag="ACG84Z_000121"
     CDS             30839..31510
                     /gene="purQ"
                     /locus_tag="ACG84Z_000121"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFP9161003.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31511..33733
                     /gene="purL"
                     /locus_tag="ACG84Z_000122"
     CDS             31511..33733
                     /gene="purL"
                     /locus_tag="ACG84Z_000122"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFP9161004.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33718..35157
                     /gene="purF"
                     /locus_tag="ACG84Z_000123"
     CDS             33718..35157
                     /gene="purF"
                     /locus_tag="ACG84Z_000123"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFP9161005.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35180..36232
                     /gene="purM"
                     /locus_tag="ACG84Z_000124"
     CDS             35180..36232
                     /gene="purM"
                     /locus_tag="ACG84Z_000124"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFP9161006.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36229..36807
                     /gene="purN"
                     /locus_tag="ACG84Z_000125"
     CDS             36229..36807
                     /gene="purN"
                     /locus_tag="ACG84Z_000125"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFP9161007.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36804..38339
                     /gene="purH"
                     /locus_tag="ACG84Z_000126"
     CDS             36804..38339
                     /gene="purH"
                     /locus_tag="ACG84Z_000126"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFP9161008.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38355..39629
                     /gene="purD"
                     /locus_tag="ACG84Z_000127"
     CDS             38355..39629
                     /gene="purD"
                     /locus_tag="ACG84Z_000127"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFP9161009.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLTGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39751..40665
                     /locus_tag="ACG84Z_000128"
     CDS             39751..40665
                     /locus_tag="ACG84Z_000128"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFP9161010.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40798..42363)
                     /locus_tag="ACG84Z_000129"
     CDS             complement(40798..42363)
                     /locus_tag="ACG84Z_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9161011.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42356..43807)
                     /locus_tag="ACG84Z_000130"
     CDS             complement(42356..43807)
                     /locus_tag="ACG84Z_000130"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9161012.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43821..44837)
                     /locus_tag="ACG84Z_000131"
     CDS             complement(43821..44837)
                     /locus_tag="ACG84Z_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9161013.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45057..46145
                     /gene="chvE"
                     /locus_tag="ACG84Z_000132"
     CDS             45057..46145
                     /gene="chvE"
                     /locus_tag="ACG84Z_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFP9161014.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46199..47725
                     /gene="mmsA"
                     /locus_tag="ACG84Z_000133"
     CDS             46199..47725
                     /gene="mmsA"
                     /locus_tag="ACG84Z_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFP9161015.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47727..48932
                     /gene="mmsB"
                     /locus_tag="ACG84Z_000134"
     CDS             47727..48932
                     /gene="mmsB"
                     /locus_tag="ACG84Z_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFP9161016.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49189..50166
                     /gene="guaC"
                     /locus_tag="ACG84Z_000135"
     CDS             49189..50166
                     /gene="guaC"
                     /locus_tag="ACG84Z_000135"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFP9161017.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50430..51854
                     /locus_tag="ACG84Z_000136"
     CDS             50430..51854
                     /locus_tag="ACG84Z_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFP9161018.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(51896..52153)
                     /locus_tag="ACG84Z_000137"
     CDS             complement(51896..52153)
                     /locus_tag="ACG84Z_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161019.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            52315..53424
                     /gene="pdhA"
                     /locus_tag="ACG84Z_000138"
     CDS             52315..53424
                     /gene="pdhA"
                     /locus_tag="ACG84Z_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFP9161020.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53427..54404
                     /locus_tag="ACG84Z_000139"
     CDS             53427..54404
                     /locus_tag="ACG84Z_000139"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFP9161021.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            54429..56072
                     /locus_tag="ACG84Z_000140"
     CDS             54429..56072
                     /locus_tag="ACG84Z_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFP9161022.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            56080..57486
                     /gene="lpdA"
                     /locus_tag="ACG84Z_000141"
     CDS             56080..57486
                     /gene="lpdA"
                     /locus_tag="ACG84Z_000141"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFP9161023.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEITILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            57648..57923
                     /locus_tag="ACG84Z_000142"
     CDS             57648..57923
                     /locus_tag="ACG84Z_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFP9161024.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            57929..58696
                     /locus_tag="ACG84Z_000143"
     CDS             57929..58696
                     /locus_tag="ACG84Z_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFP9161025.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            58864..60693
                     /gene="typA"
                     /locus_tag="ACG84Z_000144"
     CDS             58864..60693
                     /gene="typA"
                     /locus_tag="ACG84Z_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFP9161026.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            60954..62726
                     /gene="recQ"
                     /locus_tag="ACG84Z_000145"
     CDS             60954..62726
                     /gene="recQ"
                     /locus_tag="ACG84Z_000145"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFP9161027.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            62840..63142
                     /locus_tag="ACG84Z_000146"
     CDS             62840..63142
                     /locus_tag="ACG84Z_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFP9161028.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            63145..64308
                     /locus_tag="ACG84Z_000147"
     CDS             63145..64308
                     /locus_tag="ACG84Z_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFP9161029.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            64334..67762
                     /locus_tag="ACG84Z_000148"
     CDS             64334..67762
                     /locus_tag="ACG84Z_000148"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFP9161030.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISPGDLLIEVTEK"
     gene            67783..68907
                     /locus_tag="ACG84Z_000149"
     CDS             67783..68907
                     /locus_tag="ACG84Z_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFP9161031.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            68888..69334
                     /locus_tag="ACG84Z_000150"
     CDS             68888..69334
                     /locus_tag="ACG84Z_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFP9161032.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            69318..69656
                     /locus_tag="ACG84Z_000151"
     CDS             69318..69656
                     /locus_tag="ACG84Z_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFP9161033.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            69775..70335
                     /gene="rsmD"
                     /locus_tag="ACG84Z_000152"
     CDS             69775..70335
                     /gene="rsmD"
                     /locus_tag="ACG84Z_000152"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFP9161034.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            70332..70823
                     /gene="coaD"
                     /locus_tag="ACG84Z_000153"
     CDS             70332..70823
                     /gene="coaD"
                     /locus_tag="ACG84Z_000153"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFP9161035.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            70813..71856
                     /locus_tag="ACG84Z_000154"
     CDS             70813..71856
                     /locus_tag="ACG84Z_000154"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFP9161036.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            72015..72743
                     /locus_tag="ACG84Z_000155"
     CDS             72015..72743
                     /locus_tag="ACG84Z_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFP9161037.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            72859..73104
                     /locus_tag="ACG84Z_000156"
     CDS             72859..73104
                     /locus_tag="ACG84Z_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFP9161038.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            73101..73319
                     /locus_tag="ACG84Z_000157"
     CDS             73101..73319
                     /locus_tag="ACG84Z_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFP9161039.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            73455..73994
                     /locus_tag="ACG84Z_000158"
     CDS             73455..73994
                     /locus_tag="ACG84Z_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFP9161040.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            73987..76260
                     /locus_tag="ACG84Z_000159"
     CDS             73987..76260
                     /locus_tag="ACG84Z_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFP9161041.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            76298..77344
                     /gene="holA"
                     /locus_tag="ACG84Z_000160"
     CDS             76298..77344
                     /gene="holA"
                     /locus_tag="ACG84Z_000160"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFP9161042.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(77433..77687)
                     /gene="rpsT"
                     /locus_tag="ACG84Z_000161"
     CDS             complement(77433..77687)
                     /gene="rpsT"
                     /locus_tag="ACG84Z_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFP9161043.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(78077..78355)
                     /locus_tag="ACG84Z_000162"
     CDS             complement(78077..78355)
                     /locus_tag="ACG84Z_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161044.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPECLY"
     gene            complement(78617..78745)
                     /locus_tag="ACG84Z_000163"
     CDS             complement(78617..78745)
                     /locus_tag="ACG84Z_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161045.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(78825..79280)
                     /locus_tag="ACG84Z_000164"
     CDS             complement(78825..79280)
                     /locus_tag="ACG84Z_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFP9161046.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(79418..81346)
                     /locus_tag="ACG84Z_000165"
     CDS             complement(79418..81346)
                     /locus_tag="ACG84Z_000165"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9161047.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(81543..82376)
                     /locus_tag="ACG84Z_000166"
     CDS             complement(81543..82376)
                     /locus_tag="ACG84Z_000166"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFP9161048.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(82568..83272)
                     /locus_tag="ACG84Z_000167"
     CDS             complement(82568..83272)
                     /locus_tag="ACG84Z_000167"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFP9161049.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(83295..83921)
                     /locus_tag="ACG84Z_000168"
     CDS             complement(83295..83921)
                     /locus_tag="ACG84Z_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFP9161050.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            84247..86622
                     /locus_tag="ACG84Z_000169"
     CDS             84247..86622
                     /locus_tag="ACG84Z_000169"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFP9161051.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(86646..87137)
                     /locus_tag="ACG84Z_000170"
     CDS             complement(86646..87137)
                     /locus_tag="ACG84Z_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFP9161052.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            87324..88244
                     /locus_tag="ACG84Z_000171"
     CDS             87324..88244
                     /locus_tag="ACG84Z_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9161053.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            88398..88742
                     /locus_tag="ACG84Z_000172"
     CDS             88398..88742
                     /locus_tag="ACG84Z_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFP9161054.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(88932..89432)
                     /locus_tag="ACG84Z_000173"
     CDS             complement(88932..89432)
                     /locus_tag="ACG84Z_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9161055.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            89960..90043
                     /locus_tag="ACG84Z_000174"
     tRNA            89960..90043
                     /locus_tag="ACG84Z_000174"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:89994..89996,aa:Leu,seq:cag)
     gene            complement(90367..>90801)
                     /locus_tag="ACG84Z_000175"
     CDS             complement(90367..>90801)
                     /locus_tag="ACG84Z_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFP9161056.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        29441 a        15663 c        19442 g        26255 t
ORIGIN      
        1 tttttttaga catgaatatc ttatttttat tgctattttt cttaattttc cttctaacat
       61 ataggaaatg tcaaaactat tatgtgcgta tattgactgc attaccgttt ttcttaaacc
      121 tgattattta ttttggtaat acaatgggtc aaagctttac ttacgtcaat ggaaataaaa
      181 gggcaatgat ttggagtagt agtaacctga ataatctctt tacagagtta ggaacgaaac
      241 tgtcactttt ttatccaggt acttggatag ctactttagt agtcttggca ttattactat
      301 gtttaattgt tggaatttat ttaagttttg acaataagaa aacttctatt tttttagtta
      361 ttttgatgat aatgggattt tgttcaaggt taattatggg attttctccc acagtatggg
      421 cttccggaat gcggacgtac tatatacttt atgttgttat cgccatctta gtactaatgg
      481 cagttaaaga gctaatgaaa agcatgagtg tacaaaaaaa tgaatttatg caatttggat
      541 taaccgtgct tggtatttgt acctttataa taacggtgat aaacagataa tatacaaaaa
      601 atccctcgct ttagtattag gtgagggatt ttactcgttt ttcgattaat tgttttaaca
      661 cttgcaagtt tctacgagta gcttgtttcc gaccttcata tactcacctc aggctgttta
      721 catgattgta cgttcttttt gtaaaggata cagtgatatg tatataatgg cataaagaaa
      781 cgttcaaaca aaaaaactcg tgaagcaaaa ttaacttcac gagttgtagt gcagatgatg
      841 ggactcgaac ccacacgagc taacgctcac atgaccctca atcatgcttg tctgccaatt
      901 ccaacacatc tgcgtaataa taacacacta atgatagcga ggttttacat agttgtcaag
      961 ctcaaaaatg ggaggactta ttaagatgga gaaatatgac ggagaatttt caggactggg
     1021 aatgatctta ggtgtattga ttggacttgc attcggacgt tttttgcttg gttttatgct
     1081 aggaatcatt tgtggaattg caatggattg ggcagcgaat ctatggaatg actatcatga
     1141 caattaagtt ctcaacgctt gtttgtgttt ttttaatact tacgtttttc ctaaataagt
     1201 ggcaaaattt tctaggatgg agtatgatat tgaaatagta aataacaaaa aatttggaaa
     1261 gttctaactt tttgaaatga gggattggct aagtgatgag agaatttgaa aaatccaaca
     1321 aattagaagg tgtcagttac gatgttcgcg gtcccgttct agaagaagcg gagcggatgc
     1381 aagaagaggg cattagtatt ttaaaattga acacgggaaa tcccgcacct tttggatttg
     1441 aagcaccaaa cgaagtcatt cgtgatttga tcatgaatgc ccgtgactca gaaggctact
     1501 cagattccaa ggggatcttt tctgctagaa aagcaattga gcaatattgc caactgaaac
     1561 attttccgaa tgtgacgatc aatgatatct acaccggcaa cggagtgagc gaattgatca
     1621 cgatgtgtat gcaggggttg ctggacaatg gagatgaagt actggttcca atgccggact
     1681 atccgttgtg gacggcttct attgcattag ctggaggcac acctgttcat tatatttgcg
     1741 atgaagaggc agaatggtat cctgatattg atgatatcaa atcaaaaata acgagtcgga
     1801 caaaagctat tgttatcatt aatcctaata atcctactgg ggcactttat ccaaaagaat
     1861 tattagaaga aatcgttgaa gtagctcgac aaaataacct gattatttat tccgacgaaa
     1921 tctatgatcg cttagtgatg gatggtctag aacatattcc gattgctaca ttagcgcctg
     1981 atttgttcgt tgttacgctg aacggtctat ccaaatctca tcgtgtagca ggatttcgag
     2041 taggctggat ggtcctaagt ggagataagt cacacgtcaa aggctatata gaagggctga
     2101 atatgttgtc ctccatgcgt ttgtgttcca atgtattgtc tcagcaaatt atccaaaccg
     2161 cgctaggcgg ttatcaaagt gtcgatgagc tgctcctgcc aggcggaagg atctatgaac
     2221 aaagagaata tatctataat gcaatcaatg atattcctgg tctttcagcc gtaaaaccaa
     2281 aagctgcttt ttatatattc ccaaaaattg atacaaagcg attcaatatt ttggatgatg
     2341 aaaaattcgt tttggacttt ttacatgaac atcatattct acttgtacat ggtggtggat
     2401 ttaattggaa ccagccagat cattttcgaa tcgtttatct tcctaaaatg gatgatttga
     2461 aacaaacagc taagaaaatg agagaattcc tagcaaccta tcgccaaaaa tgattttaaa
     2521 aaccaaattt ttcagtagga gggccacaga caaacacact gaggctctct ttctagtgga
     2581 gttttcttaa ataactaaag tatattattt agttgcaagt cttttcttga agtttgcgac
     2641 ttcctaaagt aaaatacgaa tagaatgcga atacgcatat tttggggagg atacttatgg
     2701 aaacgttaat cgagtccttt ggaacgatca ttaaagagat tcgaaaagaa caaaaaatga
     2761 cgcaaaaaat gctttcgcat gatatttgtt cacaaagtgt attaagtcgg atcgaaaata
     2821 atgaggaact gccgaatgta ttggtgatga tgcagatttg tcaacggcta ggggtaacga
     2881 ttgatcatgt gatgaatctc tctcgaaaaa ctactcggac aaacgataaa ttatttgaac
     2941 tgttggatag ttgtttccaa aaacgtgatt atcggaagtt agaacaagta ctaaaatctt
     3001 ctgatatttc tgaaaatctg tatcaagcaa ctgactttca acgctattat tattatctcg
     3061 gtgtttgcga attcacgttg cgtcaaaata tctctcagtc cctttattat ttgaaagaag
     3121 cattaagcta ctctagccaa aaagaaagaa tccatgtttc tgacacagaa atacaactga
     3181 ttagttgtat cggaaaaata tatggtgtgg caggaaaaac ggctgaagca cgctactatt
     3241 tgagtcgaag catccaactg ctgcatcaat cagctgatga acgatcaaaa agtgaatttt
     3301 cgcaaatttt ttataattat ggaaatttct tattccatca aaatgaaatc gacgaagcgt
     3361 tagaacaggt gaatcaagga atctattggg ctcaagagaa gaatagctac tattacctca
     3421 atgatttatt tgtgcttaaa agcttaatat acaagcgtaa agaagaacca gaaagagcag
     3481 cattctatga aggcttagca caagctgtga aacaaatttc aaaaaatttg taaatggtgt
     3541 agaccattct tgacttcttc tctaaataag agtactttag aggtagaaaa acaaagggag
     3601 agaatagaat gagaactttt atctatgctg acaaattctt tttagcgtca ggtgtcaaac
     3661 atgcaggcta tcttgaaatt accgatggac tttttggtga atacaccaaa gaactacctg
     3721 agggagaagt caacatcatt gaccaaagcg gcaaatggat tgctcctggt ttggtagata
     3781 cacatattca cggctatatg aatcatgatg taatggataa tgatgcagaa ggcatcaaag
     3841 tgatgtctga aggtctgtta tcttgtggag tgacttcatt tttaccaaca acattgacgt
     3901 caagcaaaga acgtttaaaa gatgtagctg agacaatcgg caaaatgtat caggaagcac
     3961 caggagctaa aatcaaagga atctattttg aaggtccttt cttcacagaa gaacacaaag
     4021 gggcacaaaa cccaagttat ttcggggatc ctgatttgga tactttccat gaatggcaag
     4081 aagcttcagg tggtttaatc aaaaaaattg ctttagcacc ggaacgtcaa ggtgtagaag
     4141 agtttgtcaa acaagtgact gaagaaggag tagttgtttc tctaggacac agtaatgcta
     4201 cactagaaga agcgcaaaaa gctgttgaag caggcgcaag tgtatttgtc catgctttca
     4261 atggtatgcg tggattgaat catcgcgaac caggtatggt gggtgcgtta ttatctttag
     4321 aacatgtctt ttctgaattg atttgtgatg gccatcatgt acatccaaat gctgcgggaa
     4381 tcctaatgga aaaagcagga catgatcatg tcgcattaat tacagactgt atgatggccg
     4441 gtgggatgcc tgatggaaat tacaatttag gcgaatttcc agtagtagta aaagaaggaa
     4501 cagcacgtct agaatctggc aacttagctg gaagtatatt gaaattgaaa gaagcaatta
     4561 aaaatgttgt agactgggga ttagcaacac cagaacaagc agtcatgatg gctagtctga
     4621 ttccagcaat cagctgtaaa atcgatgata catgtggaaa aatcgctcaa ggacgcgatg
     4681 cagactttat cgtattgaac cctgatatga cattggaagc aacttatcta gatggcgtgg
     4741 aacgtttcca cgcataatat aatttaagtt aaccttaaaa ctaaacttct taagtttggt
     4801 tttaaggttt tttttgtgtt ctagtaaaaa tcactttaca taagtttcaa aagtttcttt
     4861 aatttcctat tgttcaataa gtaacaatgt aaagataaaa ttaaaaatgt taatacgtat
     4921 tagcaaaata aaagcttttt ttattgtgaa taaatgaaca taattaggag gagaaagatg
     4981 aacttatttg acatttttcg atcgactttg acagatatgt cgattgtcag tgcaatcact
     5041 tcaacagttt ttattatatt attagggttt gtttgtagaa aaaaggggat tttttctgaa
     5101 tctgttggaa aaattctatc gaaagtcgtc ttaacagtgg ctttgccagc actggcattt
     5161 cgagctttca tgcaagatat caatacagaa ttactgatgc aaggaatcaa tgtcttgatt
     5221 tggggattag ttatttatat tattcttatt ctagtttcaa aacctttttt cttaagctat
     5281 aaaggggata agcaaacaac gttgcgtgtc ctgacgatct ttggttctac gacctttttc
     5341 ggaacgccta tcgtcagtgc gatttatggt cctgtcggcg tgatgtattc ctcaattttc
     5401 aatattggct accgaatctt tttgtattct tatggataca taaaaatgag tggcttgaag
     5461 atggaagcta aaaatatcaa agcgatgttc gtcaatccaa tcattatcgc tacttttgcc
     5521 ggccttttca tttggctgtt ccaagggtat ctgccacaag tgtcagttac aggtgcagaa
     5581 ggagagataa gccaagtagc gtttttgcga attgaccaga ctgcaccgtg gctatttcag
     5641 ccgatggatt atttagctgg tttaagttca ccattggcgt ggctagcaat cggcgcaaca
     5701 ttaggtgaag taagcttcaa aaaagctgca tctgaaaaaa cttcatggta ttacagtcta
     5761 gtcaaagtgg tatttgtacc tgcattgaat atcgtgattc tagcagtttt gacggcaacg
     5821 aatattctac cagtcaattt tgaagcactg gcaacaatcg ttatcatgat ggctacacca
     5881 gctgcaacag tggcagcagc ctatgctatc agttttgata gggaggcact tttagcctcc
     5941 aatgcatcct tactgtcaac tatttttgct gtggtactga cacctgtatg gatcgttgta
     6001 ttacaaatga ttcatggcat aggtttattt tcataagaaa tggaggaaga aagtatgaga
     6061 atcgcatgtt acggtgttcg tccgaacgag atagattttt ttgaaaaatt gaatatttac
     6121 cattatgatc tcagtcttta tgaagaactg ttgacacatg acaatatcgt gtcagcaaag
     6181 gaccatgatg ctgtattgtt gaggggaaat tgtatagcag atgagaccaa tcttgcaaaa
     6241 atgcaggaat atgggattcg ttatgttttt acacggactg tgggagtcaa tcatatcgat
     6301 ctacaagcgg cagctgattt tggtatgaca gtagcccgtg taccatcgta ttcgccaaat
     6361 gcgatagcag agttatcttt gacttttgcc atgatgcttt tgagaaatac tgcgtatacg
     6421 acgatccgaa catctttcaa agattttcga gtggatgagc aaatgtttag tcgtgaaatc
     6481 agaaattgca cagtagggat cataggaaca ggcaggatag ggttgacgga agctgttttg
     6541 tttaagggac taggagccaa agtgatcggc tacgatattc atcagacaga agctgctaaa
     6601 aaagtattga cgttccactc gcttgaagag ttattagcca aaagcgatat tgtcagtatt
     6661 catgtacctc atatcccagg tgaaaacgat caaatgatca atgaaggatt tttagctcaa
     6721 atgaaaaaag gtagcatctt gattaataca gcccgtggag agcttcaaga taatgaagct
     6781 attttaagag ctttgaaaag caatcattta gctggttttg caaccgatgt ttttgcaaat
     6841 gaaacagagg tttttttccg atccttcaag ccatgggaga cgattccaga ccctgctatc
     6901 cagcaattag tagaaatgta ccctagagtt cttgtaaccc cgcatgtagg ttcaaataca
     6961 gatgaggcat tatcaaatat gatttcgaca agtttcgaga actttcgtga aataatagaa
     7021 actggaaaaa cgaaaaatga ggtatctctt cctaaagccc gtcaattaag ataagaaaac
     7081 atggatattc gtcaataaaa tgtttaaaaa tagtccaagt aaacagttgt tacttctgta
     7141 tacttggact attttgtatg ggataattcg atgactcaac agtaatctgt gagctttttc
     7201 cgcccattct ttgtcaattc ataacaggtt agcggccggc cgatttccaa atatttgatt
     7261 ctttcgttca atatatcttg ttctactaaa aaattcaaat atttcttgac ggatatacgt
     7321 gacagtgagc ttttttgagc cagttctttt gttgaaaaaa tagtatcttc ttttagaata
     7381 aatgcactta ttttttttaa agtcagtttt gacagacctt taggcaaatc gatgaatgat
     7441 ggtatttcgt gaatgggagt ggtgtggttg aatacttgat cgatcaattt ctgatcggct
     7501 ttttcagtcg tttggattgt ctgagagaaa gcaagatact tttcgatcgc cagctgaaaa
     7561 cgttgcaaag tgaacggttt gatcaaataa tctaaggcac cgtagcggat cacattcttt
     7621 atggtttcga tatcatctgc agcagtgatc aaaatcactg ggatatcatt tccttgctgt
     7681 ctaagccaag ataaaaaatg gataccactt tcgccaggca tgtatacatc aagcagcagc
     7741 agatctgcgt ttttttgtct gaaatatttt tttccttctt ctacatttct gaaactttcg
     7801 attacgttca tattagggat gctttccaca aaagtacgat tcaattctgc aaccattgga
     7861 tcatcttcga ttatcaggac atttgtcatc attttgatct tccttttttg gtaattctag
     7921 atagacgatt gtaccgccat ttgtttgttt ggaaaattct aaaaatccac cgtggcgttt
     7981 gacgattgaa tggatgagat tcaatccaaa cccacgattg attcccttcg tcgaaaaacc
     8041 tagcgtaaat attttttctg agatttcttc tgatatcccg acaccgtcat cgcagacggt
     8101 cacgatgaat acttcagctt ctgtgtcata gtttaaatga atccggacct gtccgtttct
     8161 ttcatgtttt tgtagcacgg cttcttttgc attatcaagt aagttcccta acacttgcaa
     8221 aagtgaatgg atggagtcat ccatctccat tttagggata aaagaatcgc tttctaacag
     8281 catttcaaca gattgttctt tggcttcgtt tattttgcct aataaaaaac cggcaattgc
     8341 aggtactttg atcagacttg agacttggcc aatctctttt ttataatttt gatttagctg
     8401 ctggataaaa tgggtgactt cttcatactt cttcaaatca atcaaaccag aaatgacatg
     8461 aagtttattc atgaattcat gggtttgagc tctcatggag tttatatatt gtttcgtccc
     8521 cccaagctcc tccattaatt tcattacttc tgatcgattt cgtaaagttg cgactgctcc
     8581 taaaaaacgg tcattgctaa aaagaggtgt aacgctagaa atagtttcta tcccatttaa
     8641 atacatggat tgagtccgaa cggtcgtttg atgctcaatc gtctctttaa acaaaacgtc
     8701 atatagatta tcactgattt ttttcctact tcgaaatcca atagctgctc tgtttggtag
     8761 aaaatgtttt ttgcaggtgt attgatcaag aggatagttt tatcagaaga gatggctaag
     8821 attccttcat ctacttcatt ttcgataatc gttttttcac ttaactgttc tgctatttct
     8881 tgtggttcaa gtccaagcag tacttttttc attttttggg caagaaaaac ggcgcctatg
     8941 atgcctacgc taagtccaat aatcaatgaa aaaacaatca ttttttgtcc atctttgact
     9001 tgattgtcaa tcgtgttgtt tgttaagcca acacaaactg caccaataat ctcttgatca
     9061 taataaatag ggacgaaata gcggaagccg aaccctaaca ttccttcttt ttcagagaaa
     9121 aattcttgtc ctccaatcac ttttttcaca tcttcatgac ttgagaaagg aagaccgatg
     9181 taacttgggt ctgcgtgaga atatcgaatg ccttcagggt ccatgacaac gataaaatct
     9241 aaattcgatg caatcatgat ttcatttgtt attccttgaa tcgcatgtgt cgggtcacca
     9301 gtctgcagct ttttttggat gagtttatca ttggcaacga ttttagcaat gctagagatt
     9361 ttatctgaca cactagatcg gttcatcgaa agaataaaat tcctgatcaa tatggcagaa
     9421 acaatcaaag aaacgaatgt ggagaaacaa acgacaagga tgatcgtgtt ctggagcttt
     9481 aatggttttt tcttaaaaaa aggaaacata ggctacctcg aaagaattta ttgtgaaaat
     9541 tttaacatga aaacaaaaat ttaacaaatt gtcaacgata aacacaacct tcctataaaa
     9601 aacaccactg agtcggtaaa agaagctata cagaattttc aaacattggt atgatagacg
     9661 tagaaatgga aggaggcgtg tatatgatag ggggaatcgc acttgagacg atttattggt
     9721 atacattgct gatttgtgca ggattggcag tcctattgat tatttttgga gatgtattcg
     9781 attttgatgg cccgcttgat ccgatgctta ttatcccttg gttaactttc acaagcttat
     9841 ttggttttct aggtgagcgt ttaacagatc aatcatcttt atttttattt attgctagtg
     9901 gaggcatatc gatagtgttg gtatttttgc ttaatttcta tatattgatg ccgatgaaac
     9961 atgccgaatc aacgatgtcg tcttctgaaa aaactctgga aggacaagta gctgttgtga
    10021 tcacaccgat ccctgtacga ggtatgggag aaattcagtt gaaaagtgtt accggttcca
    10081 ttagtcgtcc agcttgtttt tacagccccc aagaacagac agctgagcgg ggaacgaaag
    10141 tattgatcat tgagatcaag gaaagaatct gttatgtcat gccttatgaa agcatgataa
    10201 aagcttaaag gagcgtgtgt taaatggaaa taccagttgt ttttatcgcg atcgcaatcg
    10261 cagctttgat tttactgatg ttgctgatcg tctttgtagc gaagtaccag acagcaaaac
    10321 cggatgaagc gttgatcatc agtggaagtt atttaggaag caaaaatgtg cacattgatg
    10381 aaagcaataa caaaatcaaa attgtgcgtg gaggtggcgc attcgtcttg ccagtttttc
    10441 aacgttcgaa tcggatcagt ctattatcga gtaaattgga cgtctccacc cctgaagtgt
    10501 atacggaaca aggcgtaccg gtgatgtgtg atggtacttc gatcatcaaa atcggttcat
    10561 ctgtagaaga gattgctaca gcagcagaac agtttttagg caagacaaga gaagaactgg
    10621 aaaatgaagc aagagaagta ttagaaggac acttgcgctc gattcttggt tctatgactg
    10681 tagaagaaat ctatcaaaat cgcgataagt tcagtcaaag cgtacaagaa gtcgcttctg
    10741 tagaccttgc aaaaatgggg ttgatcatcg tttctttcac tatcaaagag gtcagagaca
    10801 aaaacggtta tcttgactct ttagggaaac caagaatcgc ccaagtcaaa agagatgcag
    10861 atatagcaga agcggaagct ctaaaagaaa cgcgtatcaa aaaagctcaa gcagaaaaag
    10921 aatcacaagc agctgaatta cagcgacaaa cagagatcgc agaatcatta aaagaaaaag
    10981 aactgaaatt agcaacctac aaacaagaac aagatgttgc taaagcaaaa gcagaccaag
    11041 cctacaattt agaaagtgcc cgagcacaac aacaagtaat cgaacaggaa atgcagatta
    11101 aaatcgtaga acgtcaaaaa caaatcgaac tggaagaaaa agaaatcaca cgtcgtgaaa
    11161 agcaatatga ttcggaagtg aagaaaaaag cagatgccga tcggtacgct aaagaacaag
    11221 aagcacaagc tcaaaaagtc aaagaagtga ctgaagccga agcagaacga ttccgtgtgg
    11281 aagcactggc agaagcggaa gccaataaga cacgtttagc tggacaagca gaagccgaag
    11341 cagcactagc aaaaggaaaa gcagaagccg aagcaaaaca aaagatcgcc aatgccttca
    11401 aggaatatgg cgaagcagct gtcttgagta tggttatcga tatgctaccg caattgatgc
    11461 gcgaagcagc acagccgcta ggaaatatcg aaaaaatctc tgttgtcgat acaggaagca
    11521 gttcaggaga aaccagtgga gcgaaccgag tgacaaatta tgccacaaat ttgctttctt
    11581 ctactcaaga aacactaaaa gcgacaacag gacttgactt gaaggaaatc gtagagaatt
    11641 tgtcgacacg tgggactact agccaagtaa atatgtatga agcgccaaaa gaggcagaac
    11701 aaaactcgat gaaggaagaa taaagtagta cacttcaccg ttcaatcaaa aatggaggaa
    11761 gactttttaa agttcttctc tccatttttt tattttattg caaaagaaaa ttagtcctcg
    11821 ctatttttct tttgtttttg gatcttagct tctatctctt gtaaatttgt tcttagcaat
    11881 cgttctttct tttggagttc gaccaaatct tctgatagtt cttccttctt ttctgtttca
    11941 ggaggacgaa gaaagaaatt gataccgatt gcaatgaatg tccctataaa agtatctagt
    12001 acacgttgga tagcatacaa agcggattcg ccttgaggga tgctcaacgc aatcagcaac
    12061 aacgtagcta ttgcggaaat gataccggaa ttattgttaa taccatctga cacgacgatc
    12121 acaataataa ctagaatagg aagcaagatc aattctacca aaaaatcatt gtgaaaatag
    12181 cttttgacaa aaaaataaat gatagctaat gtaccaccta atgtattgcc gatgatccta
    12241 gactttccaa aagaaacggt tgtagtcaag tcctgacgca aagaaaaaac agcagataat
    12301 gcagcaatca tcgggattcc tcgttgagtc aaatgaaaaa acaagataca taaaaaaaca
    12361 gctaaggcac ttttgatcgt acgcatacct agtcgaaaac ggccaaattg catagagatt
    12421 ctcctttttg gtctttttac tatcatacct aaacttttgt ctgatagcta gtttttcatt
    12481 attcaagtat aattaaaata aaaaaggggg aagtaaatgc gtataggaat gcgaacagtc
    12541 aaaacagtga tcagtgtctt cttttcgatg gtcacagcgg gtagcttatc gctgttgtat
    12601 tggccagctg cagggatcat tgcattatta agtgtaggaa ataccaagcg ctctacattg
    12661 cgtacgggca tgaatcgaat cgcagccttt atattagcta cggcaacagc actgttcagt
    12721 ttttttgctg ttgggtatac tatttttggc ttcagtcttt ttttattcct gttcatcccg
    12781 cttgcctctc gcttcaaatt aaccgaaggg atagtagtaa attcggtttt ggtcactcat
    12841 tatttagtgg aggaaaacat gtcttggcag ctgatcggca atgaagcggg attaatggcg
    12901 attggattag tatttgcttt gcttgcaaat gtttacatgc cagatcgtac gaagcagctg
    12961 aaggaaaacc aaatacagat cgaaaaagaa tttcgaaata ttttgagaca aatggcagaa
    13021 tttcttttat cagaaaataa agaagatgtg cagatcaaat gcgaacattt actgacattc
    13081 attcgcgaaa gccaagaaga tgccagagaa catcaagaaa actactggct cagacagccg
    13141 ctatactacg aaacttactt ctctatgaga agagcacagg ccaatgtgat taaagacatg
    13201 ctggaaaatc tagagagaat ccagcaacca gcttattatg gaaaacatat ctatggttta
    13261 ttgatttata ctgcagaaac attttcagag tcaaatgatg gcagacaaat tttaacacgt
    13321 attgaagaag tttatgtatt gtatcggcaa atgcctctgc cgactagtcg ccctgaattc
    13381 gaggatcgag cagaattgtt ccagtttttg cagtctttta aaagttttat tgaaatcaag
    13441 gcagaattct cccaacaaaa aatccaaaaa tagaggttgt gaattcagct aatattcagg
    13501 tcaaaaagct gatttcacaa cctcttcttt aaacggtgtt ctcctgtcaa ctcctcggtc
    13561 acaagtcaca atattcaaca aacatgagaa gctgtttttt gaaattgctc cttgtgactc
    13621 ggagctgaac ggtaggctca caacctcttt cttaaacggt gttcaaaagc tttcctctgc
    13681 ggtaataagt ccagccaaac gaaaaatagg aggagctatt tttgtttggc tgttcttatt
    13741 acttgatgca gaacagcttt ttcacaacct tttaaaatta catatttttc catagaactt
    13801 gcatttgatc caagatttcg atgacatctt ttgtcaagaa gagagagcga ttgggcaagt
    13861 caccttcaat catgtgtacc atattcttta tttcgtaatt cattgcttca gatgtattcc
    13921 cgctttcgat gaattccttt gtaccatctg taaataagat ctccgcacga tcagcacgcg
    13981 ggtaatcagc aatcgtcaca taaccgttct caaaggcaac gataccgact tttggcattt
    14041 ttgcctgaaa agtcaagctg acagcagcaa gttcattttc tttgttacgc aagatagtga
    14101 cggattgttc gtccacgcct gtttcaaaag gaaccattgt agaggcaact acttcaggtt
    14161 gagagctcaa aaagaaacga gcgaaagata cagcatacgt accgatatcc aacagagctc
    14221 ctccagctaa ttctggattg aagaaccggt ttttagggtc tggttctttg taactgccga
    14281 aaggtgcttg gatcattttt aaagccccca gttttcctgt atccattatt gagcgtaact
    14341 gctgataaag tggcatgttg aagattgtca tcgcttctgc taagatcaaa ttcttttctt
    14401 ctgctaagcg catagcgtca gccagttctt ttttattcat cgtgatggct ttttcacata
    14461 gaacgtgttt gcctgcttcc aatgctgcca agatatggtc gatatgctgt ctatttggta
    14521 cagcaatgta cacgatgtcg atttcagcat cgtctaacat ttcttgatag cttccgtaag
    14581 cttttggaat attgtaacgg tgagcgaagt tttccgcttt ttctgaagtt ctggaagcaa
    14641 ctgctgttag ttcgctcgtc tcttgattga agctttcggc aaactcatgt gcgatggtac
    14701 caagaccaac gattccccat tgatattttt tcatctgaaa acgctccttc atagttggat
    14761 tgagtttctt gtctgtctat tattataaca aaaatcacga agaataaaga ggagaggact
    14821 tgaaacatta aaaaaaatga aagcagcgat ttaagaggtg ctttttgatc aaaacttaag
    14881 tagaatagtt aaaaggaggg gataaacgtg catcaagtat atattgatct tattatgagt
    14941 gtattattag aacagtttga aactgaaaaa aattttttag atgaatactt gctgatcagt
    15001 ccagaacaat ggcaaaaatg gaaagatggc gagaaaaatc tgccatctga agcgatgcag
    15061 aaagtaaaaa atcttttcac tgattatgaa tggatgctaa cgcaaaagat tttgcgtcaa
    15121 acgattattt ttcccgaaaa acgaaacgtt gccgttgcag agtacaagca aatcaaaaca
    15181 cgcatcgcgc aaaaatggct tagcagcaaa gcagcaaaag tcgagctgat ccctttgaaa
    15241 aataatcagc aggctggtag ataccttgac ttgaaagtaa gtattcaata tgatgaatgg
    15301 ggctatgatg atattttgaa ttttcgtctg ccagcagatg ttcaaaaaca gatcgaagga
    15361 gaaaaaatcg aacttctcga ttgggtgaat gaaaatctgg aagaaactta cgttcatgag
    15421 gcgaatgggg aacgtgaaga acaacgaaag gatttttcaa gtgaataaat ttttaggatt
    15481 tggagcagtt gtgattatga tcgcagcaat gggctatgtt atttttagcg atgatgattc
    15541 gcatgttcaa gccggcaatc aagcagtcga acgaacaagc accaaaacaa ctgctagtaa
    15601 agaaaagaac agtcaaacaa ccagcagcaa ggtaaaggac aaagaaacaa aagatcgtac
    15661 gtccaaacaa ttgccagatg ttaaaacaga cgattggaag ctagttttgg ttggtccaga
    15721 tcacaaatta gaaaaagaaa ttgatgagtc tactcaattg gcatcattaa gtaacggata
    15781 cttgatcgac aaacgcattg ctccagaata tgaagcattt gccaaggctg ctgaagcagc
    15841 tggatttcca ttagtgatgg tctcagctta ccggtctgta tcatcccaac aacaagtttt
    15901 cgaacaaaat gtccaagatg tgatgagtcg tcaaggtgta tcagaagagg aggcgacaaa
    15961 gattactaaa gaaacgatta cggagccagg atacagcgaa caccacacag gtctggcagt
    16021 cgatgtcgtc gatcaaaact ggtacaacag ttatccttct actgtattgg atgcaagtta
    16081 cggagatcag cctggagcta aatggatcgc agataatgct gcgcagtatg gatttatcgt
    16141 tcgttatcca aaaggacacg aagatataac taagatcaca tatgaacctt ggcacttacg
    16201 ttatgtcggt aaagaaaacg ctgagtatat caccaaacac caattgacgc tagaagaata
    16261 tctgaatgaa ttaaatgaaa agtaggaatt gatcatggcg aaaaaaaagt ggaaaaagca
    16321 aaagcgcaag aatatccgtt ggccagcagt ggttgccggt gtagcagtga tactcttagc
    16381 ctttgttttt tccttgaaga atctgtcttc tccttttact gataatcagc aagaaaatga
    16441 agcgcaatcc catcagcaat ttattgaacg gcttgttccg catgcccaag aactacaaga
    16501 tggttatgga gtgcttccta gtatcatttt aggacaagct atattagaat caaattgggg
    16561 aaaaagtacc ttggctagca aatacaataa tcttttcggg atcaaggctt atggggatca
    16621 gaagaaagta agcctggaaa caaaggaatt tgttaacgaa gaatggataa ctatccaagg
    16681 agacttcaaa gtgtatgatt catgggaaca gtccatggat gaccatacac aactgttcgt
    16741 ccaaggagta gattggaatc ctgcgctgta tgaaaaagtg attacggcca ccaactatca
    16801 ggaagccgca caagcattgc aagatgcagg ttatgcgaca gaccccggtt atgcgcaaaa
    16861 aatcatccag gtcatcgaga cgtatcaatt gaatcagtat gaccggagat agcaaaggag
    16921 aagtggctga tggcagaaca atttacgcca gaaatcatga cggaattgag aaaagatatc
    16981 gtaagagtac cggaaatcat tttagaagca agcgggatca agatatttgg aaaattgatc
    17041 cgttcgatca tctttactac ggatattgcg atcatacgta atacaaatgc gaatgcagta
    17101 attgctgtgt atccttttac acctcatcca gcgattacta aaagcattat tgaggcagct
    17161 gacattccag ttttctccgg tgtaggtggt ggtttgacac aaggtgctcg ttcttcctac
    17221 atgagcatgt tcgcagaagc gcaaggttcg ttaggggtcg ttttgaacgg tcctacgcct
    17281 ttagagacag taaaagaagt ttgtcgagta gttgatattc cagttatcag tacggtaacg
    17341 tcgaaatata cagaaataga tgaaaagtta gcagctggta tttcgattat caatatcagt
    17401 gcaggtaaag aaactgcaga agcagtacgc cattttcgta aaaaatatcc tgaacttcct
    17461 atcattgcga caggtggtcc aacggaagaa agtattgctg agaccattca agcaggagca
    17521 aatgccatca catatacgcc accaagtagc ggagagcttt ttagtcgtaa aatggaaaaa
    17581 tatcgggaaa ctgagaaaaa gaatcatgaa taacaggtga gaatcaaaag acgaggaaga
    17641 gcagatagtg gctcttcctc gtcttttgta ctccagtact atttgttcag aattcaaaaa
    17701 aaagagaaat ttttttgttt ttttacctgt aatgtacata agaagagtta aaaccttttg
    17761 ttattattag cattctaaca aaaaaatgtc ttgatttatt gaagcgcttt ctatagaatg
    17821 aaaaacgaat aaaaactaaa aaaggcaccc gacaatttag tagcagctaa attgtcgggg
    17881 cttgaaaagt cagcgggaac tgaccaatca agttgccata gtcaatgctt gtgcatcgac
    17941 gtgtatattg tacctaattt catacagaat tactagttat ttttctgttt tttagggaag
    18001 agcgcacacg aagaagcatg cttatttagc tatgtcaagg atattgggca gttgtctgat
    18061 atcctttttt ctttgcgtaa ttatcctccc atcattgaag caagaagtgt ttttagcgat
    18121 gaaagaagaa tcagcactat ctaatttttc ttgaaagtat tgagttgttc atcctaggca
    18181 gaacgataag gcaagtcttg gtttttattc cccttgaaaa agatcgttta ataaatatgt
    18241 tctgtataaa aatacagtat attgaaaaat aacaatggaa gtagaggtgc agagaatgaa
    18301 gaaaagaatg agaatcatct tagctttaag tgttatgtta ttcttcttga cggcttgtgg
    18361 gcaagaagat gacaaaaaaa tcacgctgaa catggcttgg tggggttcgc aagtccgaca
    18421 cgatgcaaca gtaaaagtaa tcgagcttta tgaagaaaaa aatccccatg tgacgatcga
    18481 ttatgaattt tatgattatg aaggatatta cacaaaatta ggtacactag cagcatcaga
    18541 tgatatctgg gacattttcc aactgaacaa tcaatttcct caatacatca atcagattga
    18601 accattagat gaatatgtgg agcaagggat aattgatatt tctaatgcag atgaatccta
    18661 tttagcaacg acgacttacg acgggcaatt agttggactg tctaacgggg tgaattcgtt
    18721 tgcgattgct tacaataaaa atatatttga acaattaaat atccctgaac cagcttcaaa
    18781 ttggacatgg gatgaatttg aacaaatcag ctatcaaatc actgaagaat taggaatcta
    18841 tgctatttca agattcgaag attttatagc tggctgtatt attcaaatac cacaagttga
    18901 gaaaggattg aatttttata atcgggaaga tctatctaac agcttgggat ttgaaaatcc
    18961 agactatcta acagattttt tccagctgcg taaaaatctg gtagacaaag gggcccatcc
    19021 agaaccaggt ggtggagctg caagtacgac ggatctgtct tttcaggcgg ttagggatag
    19081 agaagcggca atggtgtttc tatcaagtaa ccagttgaca gaaatattgt caggggctcc
    19141 tgaagatatg gagattcagt tgattaatcc acctcgcaga aaagcagatg gagaatctgg
    19201 tatcccttta cgttcttcgc aaatgctgag tatggcaaaa agctcagccc ataaagaaga
    19261 agctgctaag tttattgatt tctttcaaaa cagtgaagaa gccaatgaaa ttttaaaagg
    19321 agaacgtggt gtaccaatca tgtcgaatat tcgagaacag ctcgctcgtg cagatgatgc
    19381 aactttgcaa gcgacatttg attatttaga aatgatttcc gatatggaca acggcgaagt
    19441 gaatgtcttt gatagtgctt tgaatccgga aattcaagac caatacaatc ttttagttga
    19501 aaaagtcatt tatgaagaag taacagcaga agaagcagca gagagtcttt atgagtttgc
    19561 gtcaaacatt ctaggatagc agcaggagga aggcatgaaa aaagaaaaac taaaacggtt
    19621 cttggatcaa gacaatgtgg tcggttacgt atttgcttct ccattcatcc taggatttct
    19681 attgataaca gtgataccga tgatcttgtc actttattat tcgttcaccg attatcgttt
    19741 gggaaatcca gtctcatgga tcggcttgga taattatata aagatgctga gtgatgcccg
    19801 ttttttgaac tccatccgag tcacttttct ctatgtattt gcatctgtac ctgtgaaact
    19861 gatctttggt ctattgattg cttatctttt aacgaggaat atcaaaggaa cgactttctt
    19921 tcgttctttg tattatgtgc ctagtttgat cggtggcagt atttctatcg ctctagtttg
    19981 gcgggagttg ttttctaaaa acgggttagt gaatattttc ctggaacgat taggcgcacc
    20041 tgcgctttcc tggtttagcg atcaaaaact ggtcatgatc cctcttgttt tgatgtctgc
    20101 ttggcaattc ggttcggcaa tgatcatctt tgctgcaggt atcaaagaga tcccaggctc
    20161 gtattatgaa gcggcagaga tcgatggagc gaacaaatgg cagacgtttt acaagatcac
    20221 gttacctctt ctttcgccga tcattttgta taacttggtt atgcagacaa tcgcggcgtt
    20281 tatgactttt acgcaggcat ttatcattac ccaaggtggt ccgaatgatg ccacgaactt
    20341 ttatgctctt tatgtgtata accaagcttt ttcttttaat tctatggggt atgctagtgc
    20401 tatttcgtgg atcatgctgt tgattatggg agctgtcacc tttctgattt tcaaatcatc
    20461 aaaaaaatgg gtcgttgtgt gaatgagagg aggaagaaat gaataataca gtaacgaaat
    20521 ggtttcaata cggttttatt ttgctattag gtctagtcat gatttatccg gtcttatgga
    20581 tgatcgcagg ttcttttaaa acggatcaag agattatgag tggttcgctg aatttgattc
    20641 cagagacttt tcaatgggaa aattacgcaa aaggatgggc ggggtttgct ggaatttcat
    20701 tttttacttt ctttaggaat tcgtttgtca tctctgcagt ttcgacgata gggacagttc
    20761 tgagctcgac ttgtattgct tacgcattat cgagaatcga tttcaaagga aaaagattct
    20821 ggttcgtcgt catgttagta acgatgatga ttcctgcaca agtgattttg attccgcagt
    20881 ttattattta caatcggctg aatttggttg ggacgtatgt gccgctgatt ttaccacatt
    20941 tttttggaca agcatttttc atttaccaga tcatgcaatt catggtcagc atccccaaag
    21001 agttagatga atcagcgatt attgacggat gcagcaagta tagtgtcttt accaaaatta
    21061 tttttccttt gctgaaacct tcgatcatca cgacgatcat catccagttt tattggaaat
    21121 gggacgactt catgggacca ttgatttatt taaacaagcc gagatcttac acggtatcga
    21181 ttgccatcaa attatttgca gacgctggat ctagtacgac ttacgcgagt atgtttgcga
    21241 tgtctacgtt gtcgctgcta ccggtttttc tgattttctt attcttcaat aaatatcttg
    21301 tccaggggat cagtacaagc ggtctgaagg gctgaatatg aaaaagccaa tagaagagat
    21361 gtttctttac aagctcaact actatgtctg tcggattttt ttaaccagtc ttatcagtaa
    21421 tgctcttttc gctttagttc taggatgttt gttcacttta ggattagtgc tgtctgctcg
    21481 tgttgtctat ctgatttatt ttttgatgat gtatccttct tattatctat ctgtccatta
    21541 cttggcagaa aaaaaggtat gttggaggaa aggaaaaatc aaacggatgt gtttcatcat
    21601 tacgttgttt cagctgtttg tcattatttt tgcagttgat tggtatttat tagtgggaaa
    21661 gattggagct tggtatctga ttccttttct attgtgtctg ttgctttttg tatcccatag
    21721 tttttttagt acgctaattg atatctgcaa agaagataaa gcagatagtc ttgtttattt
    21781 gatcaaaagg aatatctggc tgttgtcaaa aaacgtcaag gggtttctgt ggtatttatg
    21841 ccttttgtat ggactgttct ggtgtataca gcatgatttt ttactcactg cattactgta
    21901 tccagggctg ccatttgtca cagtattttg cttaaaagaa aaggagaatg actttaaatg
    21961 aagaaaaaat atgtacaagt cggacttggt gggagagcgc gtttttttta tgaggcaatt
    22021 gcctctacgt atcatcaaac ttgtgaacta gtcggttttt gtgatgtatc tcaaacaagg
    22081 atggattatg caaatcggat acttgtgaac aagtatggac agaaaaaagt aaagacatgt
    22141 atgccatcac aatttgagca actactggat gacgtacggc cggctgaagt cattattacg
    22201 tcagtagatc gaacgcatca tgattatatc attcgtgcaa tgaaaaaagg atatgatgtt
    22261 atttgcgaaa aacctctgac tatcgatgag gaaaaagctc aagaaataat aacggtccaa
    22321 aaacagacgg gaagaagcct gcgagtcact tttaattatc gttatgcacc gtatcacacg
    22381 aagataaagg aactgataga aagtgatgtg attggtgatg tgttttctat ccacttcgaa
    22441 tggctgttaa atacgcaaca cggggcagat tatttcagaa gatggcatcg aaataagcac
    22501 aatagcggcg ggcttcttgt tcataaatct acccatcatt ttgatctagt gaatttttgg
    22561 ttgaacagcc gtccccaaaa ggtatttgca ttcggtggat taaactttta tgggatgcat
    22621 aatgcggaga aacgcggagt agaaatattt tacagtcgat gctatggaag cgaactagct
    22681 aaagctgatc catttgctat agacctgtca gccaatgagg aattgcgaga aatgtattta
    22741 gaagcagaaa aagacagtgg atatattcgt gaccgcagtg tattttccga tgatatctct
    22801 attgaagata cactaggcgt aacggtcaaa tatgaaactg gtgcgatttt gacgtattcg
    22861 ctaaacgcgt atatgccgtg ggaaggattc aatgtttctt tcaatggcag caaaggacgg
    22921 atcgaaatga aagtgatcga aaagtcttac atcaatgcag gtggagataa aaaggatgaa
    22981 ggagcagccg ttcttcagtc catccatgtc tatccgatgt tcggtgagcc atatgaggta
    23041 atcgtcgaac aagaagcggg cggacatggc ggaggagatc cgcgtttatt agatgatcta
    23101 tttggtgaag aaaaagaaga agatccgtgg aatcgggcag caactcacgt agatggtatt
    23161 ttgtcgattt tgacaggaat cgcagcaaat cattctattg cttcaggaaa agcagtagtg
    23221 attgacgagc ttgtcagctt aaaagaataa gaatagattt acggaaatta cttcccgtag
    23281 tttataaaat cttgccttat tgccgatagg ctgtcttttg aacactattt attcggaaaa
    23341 aggggctatg acatgctttt tgtcatgcct tctttttatg tgggctgctt ttttagatag
    23401 gagaaaataa aaataactat ttaaacccga acaaaaagga ataatgcatt aaaaatcatt
    23461 agattttaca aaaaaataag taaaccacgt tgtcagtttc agaaagtagt gttagactgt
    23521 tttcaatatt tgaaacaaca ttttttattc aaatatggca aactgccttc acgtgcaaaa
    23581 cagttgcaag aaaatgaatt tacactatta ttagttttac atacctactt atatatcgtc
    23641 ataatatgga tgacagtttc tagccagtac cgtaaatgct ggactataag taaaagattg
    23701 gctatttcac ccttcttttc ttatgataaa gtggagggtg tttttcttta acagaaacat
    23761 agtaggtttt tgcacaaaag cggttatttc ggtattaata aatgataaag gagcaaataa
    23821 agtgaaagaa ttagttgaac gtattcaaaa agacggacgt atattaggcg agggcgtatt
    23881 aaaagtcgac agcttcgtca ctcaccaagt agaccctgta ttgatggaac aaatgggaaa
    23941 acggtttgca gaagtattta aagaacaagg aatcacgaaa gttgtgacca ttgaagcttc
    24001 tgggatcgca ccagctttat ttgctgcaag agaattagat gttccaatga tcttcgctag
    24061 aaaagcaaaa agtttgacga tggatgaaga attattgaca gcttctgttt attcttttac
    24121 gaaacaagtg acaagtacga tttctatttc tcgtaaattt ttatcttcag aagacaaagt
    24181 attgattatc gacgatttct tggcaaacgg acaagcggca aaaggattga tcgaattatg
    24241 ccagcaagct ggagcgcaag tagaaggaat cgggatcgtc atcgaaaagt ctttccaaga
    24301 tggacgtcag ttacttgaag aaatgggatt gagagtcgtt tctcttgcgc gtattgcttc
    24361 cttgacgaat ggacaagttg agtttcttga ggaggacgca taatcgtgga aaaagaaaca
    24421 caaaatggaa aagctgcggt tttagggctg cagcatctgc tagcgatgta tgcaggagca
    24481 gtagcggtgc ctcttttgat cggtacagga ctaggcttta atcaagaaca gatgacttat
    24541 ttgatttcaa ttgatatctt tatgtgtgga ttagcgacat tattgcaatt gacagttaac
    24601 cgatttttcg gaattggctt gcctgtcgtt ttaggatgtg cgatccaagc agtagctcca
    24661 ctgatcttga tcggaaccaa tgaaggagta ggagctatct acggatctat tatcgcttct
    24721 gggatctttg ttgtgttagt ttctggtgtc ttttctaaaa ttaaaaaact attccctcct
    24781 atagtaacag gaacggttat caccgttatt ggtttgactt tgattcctgt agcaatcgag
    24841 aaaatgggtg gaggtaatgc aacagcagct gattttggtg acaaaacaaa tctgctactt
    24901 gcatttgtga cgattctcct aattgtaggc gtgcaaatgc tggcaaaagg gttcattcgt
    24961 tcaatcgcgg tattgattgg tttagtcgga ggaagcatct tagctgcttt catgggaatg
    25021 attgatctga gcgcgattgg agatgcgccg ttgttccatg ttccacaacc cttttatttt
    25081 ggtaaaccaa ctttcgacgt atggtcgatt ttactaatga tcatcatttc catggtcagc
    25141 atggtagaat caacaggtgt atattttgca cttggtgaca ttactgggaa aaatgttgga
    25201 gaagaagaat tgaaaaaggg atatcgtgca gaaggacttg ccgttatctt aggcggtatt
    25261 ttcaatacat tcccttatac tggcttttct caaaatgtcg gattggttca actttcggga
    25321 atcaaaacaa gaaaacccat ctatttctct gcattcttct tgattgtttt aggattattc
    25381 cctaaaatcg gtgcgttagc acaaatcatc cctgagccgg tacttggtgg aggaatgtta
    25441 gtcatgttcg ggatggtggc agtccaagga atccgtatgc tgttggaagt tgatttcagc
    25501 aatgataaaa atctattgat tgttgctgtt tctgttggat ttgggctggg tttcaatgtt
    25561 acgccgacat tattcagtca aatgccgcaa acattgcaaa tgttcactgg aaatggcatc
    25621 gtaatgagta gcattacggc tatcatattg aatttgatct ttaatggatt gaaaaaagat
    25681 gaagaaatat tggaagaagc cttcaagaag taatagagca aaagaaaggt tgtgaaatca
    25741 gcgttttgac ctgattgtta gagaaacaaa cggaaaaata gttcctcgta ttttgccgtt
    25801 tgtttgagct aataccgagg gtcagctgat tgaacaccgt tgaaggaaga ggtcgtgagc
    25861 ctgccgttca tctccgagtc acaaggaaca atttcaaaaa aaagcttctc atgtttgttg
    25921 aatattgttc cttgtgaccg aggagttggc aggagaacac cgtttatcca taaaaaggaa
    25981 tgtgacctaa cttttgtcac attccttttt tttatcttta ataaacacga acaataaaat
    26041 gtttttcttt gttaacattc gaaatttctt tgacatcaaa aaaagtgatt gttaaaatat
    26101 gaatgtagaa aaactgggag gaaaaacaat gacagcaaaa atctctgtga ttatggggag
    26161 tacttcagat tgggaaacaa tgaaagaagc atgtcaaata ttggatgaat tcggtgtgtc
    26221 ttatgaaaaa aaggtcgttt ctgctcatcg aaccccagat ttgatgtttg aatatgcaca
    26281 aaacgctcga aaaaaaggaa tcaaaatcat tattgcagga gcagggggag ccgcgcatct
    26341 gccgggtatg gtcgcatcaa aaacaacttt gccggttatc ggtgtaccgg tccaatcacg
    26401 aacattaaat ggtttggatt cgcttctttc gattgtccaa atgcctggag gagtacctgt
    26461 agctactaca gcaatcggaa aagcgggagc aattaatgct ggactacttg cgatacagat
    26521 gctttccatg tatgatttag aattggaggc taaattggct gaaagacgtt caatgttggc
    26581 taaaactgtt atagaaagta gtgatcaact tggttaaacc tttgttgcct ggttcaacga
    26641 tcgggatcgt cggtggcggt caattaggtc gtatgatggc gattagtgca aaagaaatgg
    26701 gctttaaagt aggtgtgctg gatcctgtga gcgattgtcc agccgcacaa gttgcagatt
    26761 ggcatattga aagtgtctat gatgacacct ttgcgctgaa agagcttgcc agaagaacag
    26821 atgtcattac ctatgaattc gaaaacgtca gtgtagaggc gttaaatgcg attttaccca
    26881 tgtcatttat tcctcaaggg acagacttgc ttgcgattac gcaagaccgc ctgttagaaa
    26941 aatctttttt ggaaacgaat aacatcgtga ttgctcctta tgcaacgatc gtcagtccga
    27001 cggatatcca agatgcgatt gacgggatcg gctatccttg tgttttgaaa accactcgag
    27061 gcggctatga tggcaagggg cagtatgttt tgaaaagtcg ggcggatcta gctcctgcca
    27121 tggacctttt aagagaagga acctgtgttt tagaagcatg gatcccgttt gaaaaagaga
    27181 tttcgatcat ggtggcagga aatggtcaag gagatttcac gacttttccg gtcgtggaaa
    27241 acatccacca caacaatatt cttcatgaaa cgattgctcc agccgcgatt gatcaggatg
    27301 tgatcgagga ggctgagcgt attgcccgtg tgattgcaga agcagtgagc ctttcaggtg
    27361 ttttaggggt agaaatgttt ttaacaaaaa caggcgggct atatgtgaat gaattagctc
    27421 ctcgtcctca caattctgga cattattcta ttgaagcttg ttctatgagt cagttcgatg
    27481 cccatattcg aggtatttgt ggttggccat taggagaaaa agtacgtttg ataagcaatg
    27541 cagtaatggt caatgttttg ggagaacaac tgctggaaag ctatcgcttg attgagaata
    27601 agccagactg gcaattccat ttctatggaa aaaaacaagc aaaaaaaggt cgcaagatgg
    27661 gacatatcac tatcttgaca gaagacatcc agcaaacgct ggaagaaatc aaacaaacga
    27721 atatttggga ttagaggaga aaaaacatgt tagaacgtta tacacgccct gaaatgggga
    27781 atatctggac ggaagagaac aaataccgtg cgtggctcga agtcgagatt ttagcagatg
    27841 aagcttgggc agaacttggt gaaatcccgc aagaagatgt gaaaaaaatt cgtgagcatg
    27901 catcatttga tatcgatcgg atcttggaaa tcgaaaaatt aacacgccat gatgtcgttg
    27961 cgtttacacg agcggtttct gaaacattgg gagaagaaag aaaatgggtc cattatggtc
    28021 taacaagtac ggatgtcgta gatactgctt atggctatct catcaagcaa gcaaatgata
    28081 ttttacggga agacttgaaa cgttttacgg aaatcattgg cgaaaaagca aaagaacaca
    28141 aatatacagt gatgatgggt cggacacacg gtgtccatgc tgaaccaact acttttggat
    28201 tgaaacttgc cacatggtat tcagaaatga aacggaacat cgaacgattt gaacatgcgg
    28261 caaaaggagt agaagcagga aaaatctcag gagcagtggg aacgttcgca aatatcccgc
    28321 catttattga agagtatgta tgtaaacaat tggggatccg tccacaagaa atttctactc
    28381 aagttctccc tcgggatcta catgctgaat atttctcagc gatggcgctt attgctacaa
    28441 gtattgaacg ttttgcaaca gagatacgcg gattgcaaaa atccgaaaca cgtgaagtag
    28501 aagaattttt tgcgaaaggt caaaaaggtt cttctgctat gccgcacaaa aggaatccga
    28561 tcggttcaga aaatatggct ggtctagcca gagtggtgcg cggacacatg gtcactgcct
    28621 atgaaaatgt cacattatgg catgaaagag atatttctca ttcttcagca gaacgaatca
    28681 tcttgcctga taccacgatt ttattgaatt acatgttaaa tcgttttggc aatatcgtta
    28741 aaaatctaac ggtctttcct gaaaacatga agcggaatat gtctgcaaca tttggtttga
    28801 tttatagcca gcgcgttatg ctgaaattga tcgataaggg aatgacaaga gaagaagctt
    28861 atgatcttgt tcagccaaaa actgcgtacg cttgggacaa ccaagtgcag ttccgcccgc
    28921 tgttagaaga agatccaacc atcacatcgg tattatctaa agaagaaata gacgatgcct
    28981 ttgattatca tcatcatttg aaaaacgttg acgtgatatt caaacgagta ggtttggaat
    29041 aaagaagagt gagttgcaaa attcaattaa aatagaatag caaaaataac caaaaaagaa
    29101 gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc aataatagga
    29161 acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa aaatagagga
    29221 attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga tgttgcagca
    29281 agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg atacgataat
    29341 gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct ttgtgttctg
    29401 tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct cggcggattt
    29461 ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg atcgacagca
    29521 aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa agctgacctt
    29581 gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa atttttagtt
    29641 aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta taagattttc
    29701 gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca tatttttgtt
    29761 gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa aacgatgtat
    29821 ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac ttttgtatga
    29881 aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga tagaatattt
    29941 agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa aaggagaatt
    30001 gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa taaaaaatca
    30061 ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa ttatccctct
    30121 ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag gtgttcccga
    30181 aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc agttggatga
    30241 tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg aagaaatcag
    30301 tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat ttgctaaggt
    30361 cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac aaattttgct
    30421 tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga atgaacatat
    30481 ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc aagaagtata
    30541 taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt cgtaaaagta
    30601 tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa aaaagcagtc
    30661 catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt tgagatacaa
    30721 cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga caagctgctt
    30781 gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga agtataacat
    30841 gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt tatgggcagt
    30901 tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct ctttagaagg
    30961 atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga gatgcggtgc
    31021 gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag aagggaaacc
    31081 agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt tgccaggtgt
    31141 actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga aagtcaaccc
    31201 caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc cagttgctca
    31261 tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa aaaataatca
    31321 gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg cagggattac
    31381 gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag tagaagactt
    31441 gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact tcggaaaggt
    31501 gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga aaaaaagaat
    31561 ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag atatcttagg
    31621 aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg aacattgttc
    31681 ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc atgtgttgca
    31741 aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag ttgtcttcaa
    31801 agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg cgacaggagt
    31861 tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt tgctagattc
    31921 attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag aagtagttgc
    31981 aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg aaattgcatt
    32041 tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt tgattgaaca
    32101 caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt atgtaggtgc
    32161 aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat ttaatcaaga
    32221 agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa agctgctgct
    32281 tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta tacaggatat
    32341 gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg gctcaggact
    32401 tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt atgaaatgat
    32461 gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg aagaaaaaat
    32521 ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag taacagacga
    32581 cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag tcgatgcatt
    32641 agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa tcgtagaatt
    32701 tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat tgcttgatct
    32761 gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg attcacaagt
    32821 acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg ttagagggac
    32881 gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt tggatccaaa
    32941 aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta gcggtggtaa
    33001 gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag aagttttttg
    33061 ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag gaactcctgt
    33121 tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct atccaacacc
    33181 aatgattggt atggtcggat tgattgagga tcataaacat atcactactc aggaattcaa
    33241 aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg atggcagtga
    33301 attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg atctatccat
    33361 tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga ttgaaagtgc
    33421 tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt tcaaacatca
    33481 gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag aaactcaatc
    33541 aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa tgatgggaga
    33601 tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt cagcaactga
    33661 cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg caatcgtatg
    33721 tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg gggtcatcca
    33781 gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg acaagaaggt
    33841 gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt ggggctgctt
    33901 tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc tgcaatcgga
    33961 catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc ttttctattc
    34021 aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa tgctcgttcc
    34081 cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga tacggagata
    34141 ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt aaaaagtgct
    34201 ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc aatgattgcc
    34261 gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa cggagcatac
    34321 gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat aagagatgtc
    34381 cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg ctttacgaag
    34441 gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc agattcaaac
    34501 atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt agcgaaagaa
    34561 tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc agccgcaagc
    34621 ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa tcaatacatt
    34681 gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg aatgaaatta
    34741 tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga ttcaattgtt
    34801 cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc aaaagaagtc
    34861 catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat tgatattcaa
    34921 acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga atgtatcggt
    34981 gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg tctggaaaaa
    35041 gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc gacgccgtta
    35101 tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt cttttaaaag
    35161 cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag ctggcgtaga
    35221 tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa aaacggaacg
    35281 tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat cggtctttca
    35341 attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat tagcagtggc
    35401 aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt gtgtcaatga
    35461 tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa cggggaaaaa
    35521 tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg ttcaaggaaa
    35581 tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag gtaatgatta
    35641 tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga caggagaaac
    35701 gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt caaatgggta
    35761 ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat caaaactgcc
    35821 agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct atgtttcttc
    35881 cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca ctggtggagg
    35941 gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa tcaaacttgg
    36001 ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa ttcctgagat
    36061 ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcg aagaatcgaa
    36121 agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg aaatcgggaa
    36181 agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat gagaatcgct
    36241 gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct atcgaaaaaa
    36301 ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata tgttttgaaa
    36361 cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt tgattcaaaa
    36421 aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga tttgatcgta
    36481 ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga taaaagaatc
    36541 atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat acgtgatgcc
    36601 tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca aggtgtagat
    36661 actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac gttcgattct
    36721 ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat tagtgaaatt
    36781 attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca gataaaactg
    36841 ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt tcaacaggag
    36901 gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa gaagtgacag
    36961 ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc catggtggtc
    37021 ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa aatatccaac
    37081 caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg aaaccagatg
    37141 tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg ctccgtagtg
    37201 cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat gaagaagtac
    37261 tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa ctagcggcaa
    37321 aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta acggattggg
    37381 tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa acgcttcgtt
    37441 acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg gaaaaatatt
    37501 cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat atccgagatg
    37561 cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc gccttgaaac
    37621 acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg gaagcagcgt
    37681 atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga gaagtagatc
    37741 tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc ccttcttata
    37801 cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg acagtagact
    37861 ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt ggacttcttg
    37921 tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg acaaaacgta
    37981 agccgactcc agcagaagca aaagcattag tgtttgcttg gagagctgtc aaacatgtga
    38041 aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga gccgggcaga
    38101 tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa atggaaggtg
    38161 cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat gcagccaaac
    38221 atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat tctattgata
    38281 tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt agacattaga
    38341 gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa catgcaataa
    38401 gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca ggaaatccgg
    38461 ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat tcagcgttaa
    38521 tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa gttcctttgt
    38581 taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt ccgacaaaag
    38641 cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat acttatcaaa
    38701 tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg tatatcaaag
    38761 aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa ggtgtagtcg
    38821 tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac cagcatcgat
    38881 ttggggatag tagcaaaaaa atcgtcgtag aagagttttt gacaggagaa gaattctccc
    38941 ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa gatcataagc
    39001 gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat tcaccagtac
    39061 cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa ccagcggctt
    39121 tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt ttgattgcta
    39181 cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct gaaacgcaag
    39241 tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta ttagagaatc
    39301 gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg gttgcagctg
    39361 ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg gaagaagagc
    39421 tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga gcaggaggac
    39481 gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa aaaatttaca
    39541 ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt ggagaaaaag
    39601 ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa aaaatacaac
    39661 aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt ggtacacttt
    39721 tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg tacttctgat
    39781 cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga agatccagta
    39841 aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc agatatttat
    39901 ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc aatcaaacga
    39961 gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt tgatttttct
    40021 aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat ggattatgtg
    40081 gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt agctgaagcg
    40141 tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa tcaaaaacca
    40201 atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa tcagctgcaa
    40261 tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat gacagatgaa
    40321 gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga tatgacgatc
    40381 caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg gaacgaaaaa
    40441 ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac gacaccaact
    40501 ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat cgccggtacg
    40561 atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat gtctcgggaa
    40621 gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt gtcataagca
    40681 ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt cagcttcgag
    40741 atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt tcgtttatta
    40801 gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa tcccttgttt
    40861 tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa aagcaatatc
    40921 tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc tttgttctgt
    40981 cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga aatgagaggg
    41041 acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg taaaattttc
    41101 tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg aaggctgtga
    41161 gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa gcgagtcgtc
    41221 ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt gcgggatttt
    41281 cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac gatataatcg
    41341 tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag atacttcgtt
    41401 tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat caactggaag
    41461 tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg aactggcggt
    41521 ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc tttctgcgac
    41581 aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat ggaccaacgt
    41641 ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa ctattaaaaa
    41701 tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc taaataaaaa
    41761 cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt ggtttgctgc
    41821 taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag caagtttcaa
    41881 tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat tttttttcaa
    41941 ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta aagcagttac
    42001 tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca gataatcatc
    42061 tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac taataaatat
    42121 gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc cgtccatgaa
    42181 aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg aagacagtgc
    42241 catctcacca tctccagctt cgccgacata agtgattgga taataagaac caaggacagt
    42301 tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa aaactttata
    42361 catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg acagttgttc
    42421 cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa taaagaagga
    42481 gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg atccctttgg
    42541 ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg ttgtctataa
    42601 ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat cctttgtgac
    42661 ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag atcattttta
    42721 aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc atatggccgt
    42781 atcttatttt taagatgact agataatcat tgatatggct aatttctttt tcaagaggaa
    42841 tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca tgggtcatag
    42901 tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc aaactgttat
    42961 aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt gctaaatggt
    43021 attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt ttattcatgc
    43081 tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag ccaaggttcc
    43141 ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg acctttctct
    43201 ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact ccaagttcca
    43261 ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt gctaagtcga
    43321 tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca gaatctacct
    43381 gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta ttgatcagct
    43441 cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac gtactaattt
    43501 ctttaagtgt atttgtatta tttttgctct ctcgaatatc attcctaagt tcttctagga
    43561 tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc cacatacttt
    43621 ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata tttgcgatcg
    43681 tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc aaagggataa
    43741 cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg cttaaatttt
    43801 ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat attctgctgg
    43861 gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt ttgaatattt
    43921 ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt acactcgact
    43981 acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc atcaatagtt
    44041 acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc taaagcaccg
    44101 tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc atttgtttct
    44161 aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac aattcggtga
    44221 acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt tggtttacga
    44281 ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt ctctgaacca
    44341 gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt gctgacaaat
    44401 aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac gaaaagctcg
    44461 ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc tcgctttgct
    44521 tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat catatccact
    44581 ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat gtagccattt
    44641 cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc agtatgcttt
    44701 ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg gtcaggtgct
    44761 tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag ggctaaaaaa
    44821 aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta tcttatcaga
    44881 taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa acttaaaaaa
    44941 atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa aaaatcaatg
    45001 ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga taaaaaatga
    45061 aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc attctattaa
    45121 gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga atcgctatgc
    45181 cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg gaattagaaa
    45241 aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat caagtagcac
    45301 aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct atcgatggtt
    45361 cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg atcgcctatg
    45421 atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat aattttggag
    45481 taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa ggaaaaggac
    45541 cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta atcaattaca
    45601 acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc gtgccatctg
    45661 gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg gcgcaagcaa
    45721 ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct gttttgtcgc
    45781 catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg tatgggagtg
    45841 aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc gttaaatcga
    45901 tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta gcaaaaaata
    45961 cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat gatactgaaa
    46021 cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta tctgtcgata
    46081 aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc gatctgaaaa
    46141 attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga taagaattat
    46201 ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa tccgagcgtt
    46261 agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg gagaaaacgg
    46321 agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg gctcctatga
    46381 cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag atagtgaaga
    46441 aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt caataaaaga
    46501 gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg aactgacaga
    46561 aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga atcttctagt
    46621 atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat tatcaaaatc
    46681 cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag aaagcgcgaa
    46741 tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca ttatttcaca
    46801 taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg atggacagac
    46861 gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg gaatggtggg
    46921 cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag tttattttaa
    46981 agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa acgaccacat
    47041 caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg gagcgggcag
    47101 aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat ccggacgtat
    47161 attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg caaacggact
    47221 cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg atattcggga
    47281 aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag ataaagaaaa
    47341 agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa actccatcca
    47401 tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat ccaagtggct
    47461 gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag atgttggggc
    47521 aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag ctgtctgtct
    47581 tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata cgatgaacga
    47641 aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct tgatgaaatt
    47701 aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg gataaaaaag
    47761 agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac agcatggtga
    47821 tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt ttctggcgtc
    47881 cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta gctgcaggga
    47941 tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg atggcgtttg
    48001 ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg atgacagtta
    48061 tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg gtagcttatg
    48121 cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt ggactgacac
    48181 aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa aaaatgtcta
    48241 cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca ttgattttag
    48301 gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat cgtcggaaaa
    48361 atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta tttacagcag
    48421 tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg attattttga
    48481 tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca gtagcaggtc
    48541 gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg atcaaaacaa
    48601 agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta gctggattag
    48661 ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg gaactggatg
    48721 caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga acaatcatgg
    48781 gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg attttaggcg
    48841 tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc gttgtgctag
    48901 acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca gaaaaaagac
    48961 tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca ttgtttcgtt
    49021 tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc tttttgctct
    49081 tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc ttgattaaat
    49141 taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat gaaagtattt
    49201 gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg ttctgaatgt
    49261 gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc tgccaacatg
    49321 cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta tttctatatc
    49381 atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa aaagcgtgga
    49441 ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat agagaagttg
    49501 gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg acatgctaac
    49561 tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt tgtgattgcc
    49621 ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc agatgcaaca
    49681 aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg ctttgggact
    49741 ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa gccgatcatc
    49801 gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt tggtgcgaca
    49861 atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga aacaaaagtc
    49921 gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca aaaaggcgaa
    49981 aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt gaaagataca
    50041 ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg aagagatctg
    50101 gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa tggagacaca
    50161 atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca ttaagtaata
    50221 agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt attatcgcag
    50281 atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt tttgtcacag
    50341 tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta aaatcaaaag
    50401 aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa aaacaaggac
    50461 cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga aggatcaatc
    50521 ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg aatcgttcca
    50581 ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc aaacgtggca
    50641 gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga atcgattggc
    50701 ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa ataagagaag
    50761 caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg ccagatgagc
    50821 ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg gaagaaaaag
    50881 aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat ttggaaagta
    50941 aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt cagcaagcaa
    51001 tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta gagtcacctt
    51061 ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt gggataccga
    51121 tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa aataaattga
    51181 aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg agtcaaaaac
    51241 gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt gaagacgatg
    51301 tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga acgattgatc
    51361 cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca acgaaaatcg
    51421 gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa gaaatgatgg
    51481 agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat gaagcaattg
    51541 atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg ataagcgctt
    51601 ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac tatgcctgga
    51661 ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta gatatgggtc
    51721 ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga atcaattaca
    51781 gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt ctagaaaagt
    51841 ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct tggatttaaa
    51901 tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact aagaaaaaac
    51961 cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa caaaactgta
    52021 taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa aatagaaaaa
    52081 atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat gctgttaata
    52141 tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt gtatttctca
    52201 taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt tattcactgt
    52261 ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg acaaatggca
    52321 aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc agatttccca
    52381 gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt acctgattta
    52441 tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt attagaccaa
    52501 cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac tgctggacaa
    52561 gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct tcttccaggt
    52621 tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc ttttttatgg
    52681 tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct accaccacaa
    52741 attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt gaagaaacga
    52801 aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca aggtgatttt
    52861 tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta tatccaaaac
    52921 aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac acttgcacaa
    52981 aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc gcttgcagta
    53041 tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc agtcctaatc
    53101 gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc aacccgctac
    53161 cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg cttccgtaaa
    53221 tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat cgaagcaact
    53281 aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca aaaggtttca
    53341 gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca aattgcaatt
    53401 tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa gcaatcacag
    53461 atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt gaagatgttg
    53521 ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc ggagaagacc
    53581 gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc ggtcttgcgt
    53641 tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc gaagcaatgg
    53701 acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact agaaatctac
    53761 ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg cattcggata
    53821 atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct tccaaccctt
    53881 atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt gttttcctag
    53941 aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct tacgaagttc
    54001 ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc acatacggag
    54061 caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat atatctgttg
    54121 aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt caatccgtgg
    54181 aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc gttgccgcgc
    54241 aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca atcggacgag
    54301 tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg ttgccaaatg
    54361 caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag aagggacgaa
    54421 acaaagtcat ggcttatcaa tttaaattgc cggatatcgg tgaaggaatc gcagaaggtg
    54481 aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat acattactag
    54541 aagttcaaaa tgacaaatca gtagaagaaa tcccgtcacc tgttacagga acggttaaaa
    54601 atgtgattgt tccagaaggt accgtagcaa atgttgggga tgtattagta gaaatcgatg
    54661 caccaggaca cgaagacaat gaaggggaca gtggtgtagc cgcagaatcc caaactccag
    54721 ctaaaccggc tgctgaaccc actgttgata cagaatcagc tggatcgtca agcgaaggag
    54781 tcttccaatt taagttaccg gatatcggtg aaggaatcgc agaaggtgaa atcgtcaaat
    54841 ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa gttcaaaatg
    54901 acaaatcagt agaagaaatt ccgtcacctg tcacagggac agttaaaaac gtgattgttc
    54961 cagaaggcac tgtagcaaat gttggggatg tattagtaga aatcgatgct cctggacaca
    55021 atagtgcacc gtcaactagt gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat
    55081 caggttcagc aagtgtcgtt gaagctgccg atccaaataa acgtgtattg gctatgccat
    55141 ctgttcgtca atttgcccgt gaaaaagatg tagatatctc acaagtaact gcaactggaa
    55201 aaggtggcag agtaacaaaa gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg
    55261 caccagcgaa atcagaagcg ccagaagcgg cagcaccgaa agaagcagct cctgcagcag
    55321 aaagcaaacc agctgcacca gcaaaaccat tcaagtccaa cttaggagac ttggaagaac
    55381 gtgtagcaat gacgccaaca cgtaaagcta tcgctaaagc aatggtcaac agtaagcata
    55441 cagctccaca cgtgacattg catgatgaag tagaagtgtc taaactatgg gataatcgga
    55501 aacgatttaa agaagttgct gctgcaaatg gtacgaaact tactttcttg ccatatgtcg
    55561 tgaaagcttt aacagcgact gttaagaaat acccagtatt gaatgcatct atcgacgatg
    55621 caaaccaaga aatcgtttat aaacattact acaatatcgg tattgcaact gatacggatc
    55681 acggactata tgtaccaaat gtgaaagatg cagaccgcaa aggaatgttt gctattgcag
    55741 acgaaatcaa tgagaaagca aaattagctc atgacggcaa actatctgca gaagatatgc
    55801 gcaatggaac aattacgatc agcaatatcg gatctgtagg tggcggttgg tttacaccag
    55861 tcatcaacta tccagaagta gctattttag gtgtaggaac gattgcacaa caaccaatcg
    55921 taaatgctga aggcgaaatc gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc
    55981 accgtatcgt agatggagca actgcgcaac aagcaatgaa taatatcaaa cgtcttttag
    56041 ctgatccaga gctattaatg atggaaggat gataaacaaa tggtagttgg agattttgct
    56101 gtagaattag atacagttgt aattggtgcg ggacctggtg gctatgtagc tgccatccgc
    56161 gctgctgaaa tgggacaaaa agtagcaatc attgaaagag agtatattgg cggtgtttgt
    56221 ttgaatgtcg gctgtattcc ttcaaaagca ctgatagctg caggacacca ttatcaagag
    56281 tcactagatt ctgaaatgtt tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa
    56341 acacaagaat ggaaagaaaa caaagttgtc catacgttga cttctggtgt tggtttccta
    56401 ttaaaaaaac ataaggttga aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca
    56461 ctacgcgtca ttcatccaga ttcagctcaa acttattcgt tcaataacgc aatcatcgca
    56521 acaggttccc gtccaatcga gattccagga tttaaattcg gaggacgtgt gttagattct
    56581 actggcggat tagcattgaa agaagtacct aagaaatttg tgatcatcgg tggcggtgtg
    56641 attggtgccg aattgggcgg agcgtacgca aacttaggag cagaaataac gattcttgaa
    56701 ggctcaccac aaattttacc aacttacgaa aaagatctag taaaattagt agaagatgat
    56761 ttcaagaaaa aaggcgtaac agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac
    56821 ggtgacagcg tgacagtgaa atatgcagtg gacgggaaag aagaatccgt tactgctgat
    56881 tatgtgatgg tcactgtagg tcgtcgtccg aatacagatg atatgggctt agaacaagcg
    56941 ggtgtcgaag taggagaacg aggattgatc acggtggata aacaaggacg tacgaacgta
    57001 cctaacatct atgccatcgg tgatatcgtt ccaggggcgg cattagcaca caaagccagt
    57061 tatgaagcaa aaatcgctgc tgaagcaatc tctggcaaaa aagtagctgt agattataaa
    57121 gcaatgccgg cagtagcctt cactgatcct gaattggctt ctgtaggtat gacgatcaaa
    57181 gaagcaaaag atgctggtat cgaagcaaaa gcatataaat tcccattttc agggaacggt
    57241 cgggcattat cgcttggtaa aacagaagga ttcatccgtc tagttacgac gatcgaagat
    57301 aacgtgctta ttggcgcgca aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta
    57361 gctttagcaa tcgaatcagg aatgaatgct gaagatatcg ccttgacgat tcatcctcat
    57421 ccatctcttg gcgaaatcgt catggatgct tcggaattag cattaggttt accaatccat
    57481 atttgatttg aataatacag gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta
    57541 gaattatcaa taatattatt atgtaaactt aaaaatatga caacttcttg gtttattacc
    57601 acttcctatg ctacactgaa gaggaatatg aaataggaga gttgaagatg caagaatatc
    57661 agtatccact tgatttagat tggacaacag acgaaatggt cattgtaatg aagatgtggg
    57721 aagatctgga acgtgcgaat gaaaaaggga taaacaatga agcttttttg aagacttatc
    57781 agcagtttaa aactgttgtc aaatccattg gtgaggaaaa acgattggga cgggaatttg
    57841 aaaaagcttc cggttattct ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca
    57901 aaactttgag aatgaacggg tgagataaat ggaacagatg attgatcata tcaagtcctg
    57961 gcttgaagaa gctggtgaga aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa
    58021 atcaaatcga acggatctag taacaaatgt cgatcgaaac atccagaatt ttctaatcga
    58081 aaaaatccat tcctttgatc cagaggcgaa aatattggca gaagaagaag ggtgtaatca
    58141 attatcggat ctcgatggaa gagtctttat catcgatcct attgatggca ccttgaattt
    58201 tgtgattgaa ggggaaaatt tttgtattat gctcgctgtt tatgaatccg gcgttggaaa
    58261 gcttggtttc atttatgacg tgatgagaaa tgaacttttt tggggtggaa aaggaatagg
    58321 cgtgtataaa aatgatgagc cattgcctag accagcaaat aaatccttat cggaaggctt
    58381 acttggtgtg aatagttatc ttttcggtca taataaatat ggaatccgag aaattgcgga
    58441 aagcagcatg gggacacgta tgtacggatg cgctggtctt gaactagtgg caatcttgaa
    58501 aggaaaccac attgcttata tttcaaacct tagcccttgg gattatgcag cgggaaatgt
    58561 cttattggaa gagtttggta tggtaacaag cggtcttttt ggtactcctt tgacatttga
    58621 aaaaagggaa tactatttag cagggacttc ttgtgcatat gcagaaatcg cagacctttt
    58681 gaaaaaagaa ggctgaaaaa aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa
    58741 agattaattt tctcgaaaaa atgaaaacat tttactatat ttcatgaaaa aagtctgcta
    58801 taattagcag tcgagtaaaa tttgccctgt cataaagaac caataaaaaa ggagttagtt
    58861 acattgaatt atagaaacga tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga
    58921 aaaacaacat tagttgatga actattaaaa caatcagata cattagacgc acatacgcaa
    58981 ttgcaagaac gtgcgatgga ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta
    59041 gccaaaaaca cagctgtaga ctataaaggt attcgcgtaa acatcatgga tactccagga
    59101 cacgcggact tcggtggcga agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg
    59161 gtcgtagatg cgtatgaagg aacaatgcct caaacacgtt ttgtattgaa aaaagcactg
    59221 gaacaacata tcacaccaat cgttgtcgta aacaagattg acaaaccttc tgctcgtcct
    59281 gagcatgtcg tagatgaagt tcttgaacta ttcatcgaat taggagcaga tgatgatcag
    59341 ttagactttc ctgtgattta tgcatctgca ctaaatggta cgtcaagctt gtcagatgat
    59401 ccagcagatc aagaaccaac catggcacct atttttgata caattattga aaaaatccct
    59461 gctcctgtcg ataacagcga cgaaccatta caattccaag tttcattact tgactacaac
    59521 gattatgtag gtcgtatcgg aatcggacgt gtatttagag gaacaatcaa agtaggagac
    59581 caagtagcat taattaaatt agacggaaca gttaagaaat tccgtgtaac gaaattattt
    59641 ggtttctttg gactaaaacg tctagagatt caagaagcaa aagctggaga cttgattgct
    59701 gtctcaggta tggaagatat ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat
    59761 gcgttaccta tccttcacat tgacgaacca acattgcaaa tgactttctt agttaataat
    59821 tcaccatttg ccggtcgaga aggtaaattc gtaaccgctc gtaagattga agaacgtttg
    59881 atggcagaac ttcaaacaga tgtatcctta cgagttgaac caacaaactc tccagatgca
    59941 tggacagttt ctggtcgtgg agaattgcat ttgtctatct tgattgaaaa catgcgccgt
    60001 gagggatacg aattgcaagt atctcgtcca gaagttattg aaaaagaaat cgacggtgta
    60061 aaatgcgaac cgtttgaacg cgtgcaaatc gatacaccag aagaatatat gggtagtgtt
    60121 atcgagtcct tgagcttacg taaaggtgaa atgcaagata tggtccatac aggaaacgga
    60181 caaatccgtt tgacattctt aacacctgcc cgcggtttga ttggttattc aactgaattc
    60241 ctttcaatga cacgtggtta cggaatcatg aaccatactt ttgaccaata tctgccaatg
    60301 cttcctggtc aaattggcgg acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa
    60361 gcaacgactt attctatcat gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt
    60421 acagaagtat atgaaggaat gattatcggg gaaaacagcc gtgataatga tttgactgtc
    60481 aacatcacga aagcaaaaca aatgacaaac gtacggtctg ctactaaaga ccaaacatct
    60541 gtcatcaaaa aaccaaaaca attgacgttg gaagaatctt tggaattctt gaatgatgat
    60601 gaatattgcg aagtaacacc agaaagcatt cgcttgagaa aacaaatttt agagaaaaat
    60661 gctcgtgaaa aagcatctaa aaagaaaaaa taatctgtaa aaggatgaag agagaaacca
    60721 gcttgttata aaaaatagct ggtttctttt tttgtccaac tcttttctgt ggagaagtca
    60781 tctttgtcaa tggacataaa ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa
    60841 aaacttattt ctagagagtt tttgtttcat aataagataa tgtttcacga aaggagatca
    60901 acttgtcctt cgaagaaaat cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg
    60961 acttattaaa acaatacttt ggctatgatg agtttagacc tggtcaaaaa gaaattatcc
    61021 agaaagtcat tgatcaggaa aatgtattag gaatcatgcc taccggaagt gggaaatcaa
    61081 tctgttacca gcttccagct ttactattag atgggcttac tgtggttgtg tcccctttaa
    61141 tctctttgat gaaggatcag gtggacgcgg cgaatcaatt aggtataccc gccactttta
    61201 tcaatagctc gttagatggt tacgaaacag ctagacgctt ccaagaaatc gatagacagc
    61261 agtaccgttt actttatatc gctcctgaac gttttatcat gccggatttt atccaagcaa
    61321 tgaagcgatg gaacgtccgt atgatcgcta ttgacgaggc acattgtatc tctcagtggg
    61381 ggcatgattt ccgcccaagt tatttacaga tggcgaacca gctagatcaa ctgccaaatc
    61441 gtcctgtaat tgttgctttg acagctacag cgactgtgca agtagctgct gacataaaaa
    61501 gacttttaaa aattccagaa aacaaccata ttcagactgg ttttgaacga gaaaatctac
    61561 gatttcaagt aattaaagat caaaaaaaag aacaatatct aatcgaatat ttaaagatca
    61621 acaaaaatca atctggtatc atttatgcag caacgagaaa agaagtagac cgtctctatc
    61681 atttgcttaa aaaattcgat ttttccgtgg gtagatatca tggtggtcta aatgagaatg
    61741 agcgaacaga aatgcaagaa gcctttttat acgatcgctt gcagctgatt gtagcgacaa
    61801 atgcatttgg tatgggtata aataaaagca atgtccgttt tgttatccat tatcaaattc
    61861 ctggctctct agaagcatac tatcaggaag ctggtcgggc gggaagagat ggtctttcca
    61921 gtgaagccat cctgcttttc tctcctcaag atatccaagt ccaaaagttt tttatccagc
    61981 agtcccaaag agaagaaggg caaaagcaaa aagaatatga aaaattaaaa gcgatgacag
    62041 aatacgtgta tattgagtcc tgtcttcagc aatacatcct aaactatttt ggcgagacaa
    62101 gcagtccgtg caaccgttgt ggtaactgtt tagatgacag agaaatagta gaagtaacga
    62161 cagaagcaca gatggttctt tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa
    62221 tgctgatgaa agtcttagca ggatcgaaag aacaaaagct gcaagcttta ggttttggac
    62281 atttatctac ctatggactg atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg
    62341 aatatttgat atcgaatggc tatcttctga ccatcaatgg tgagtatcct gttttgaaag
    62401 taacagaaag agggatacaa gtattgaaag gacaagaatc tgtttatcga aaggaaccca
    62461 agaaagtcca gcagctatcg gatgaagaaa ccgatacact atttgaagtg ctgcgggaac
    62521 tgcgaacgga tctagcatca gaagcaggcg ttcccccgta tgtcgtattt tcagattcca
    62581 cattgaaaga aatgagccga atacgtccat caagcagatt ggagatgctt cagataaaag
    62641 gagttggcca aagcaagctt gataaatatg gcgaagcctt tttatctcgg ataaaaaatg
    62701 cggactctaa cgttctggat aagtagaaag aacgaatacg taaaaatgaa taaaaacaac
    62761 tggttaaatc tgtttttttt gctccttatg aaaatcaaat atgttataat taaggaatta
    62821 gaatgggagg taagcacaga tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa
    62881 tgatgaagca gaacggatca aacgattaat ccgaaatcaa aacaacagtc tctgtatctc
    62941 acaatgcaaa gccttcgaag aagtggtaga tacacagatg tacggctttt cccggcaagt
    63001 cggttttgct gtccgtatag gagtaatcgg aaagaacgag ggccagctga tgttaagtga
    63061 gctagaacga gaattgaatc agttatatag tgaggtttac caagaaattt atgataaaaa
    63121 agaagttggc aaggaggaat agacttgcct aagaaagtga aaaaaaggca tctattagac
    63181 tatagcatct tgattcccta tttaatttta tgtgtattgg gattgatcat ggtatatagt
    63241 tctacgtcgt atctattatt agaaaacgga caaaatccgt ccgcatcagt cattaaccag
    63301 agtatttttt gggtgcttag cttgattgct atcgcactac tttataaaat gaaaacagat
    63361 gttttgaaaa accagcgttt gatcatggca gccatcgcag ttttgacgat tttgctgctg
    63421 attgttgtgt tttttggtaa ggagatcaat ggggcgaaag gttggctgca aattgcagga
    63481 ttctcgatcc aacctgccga atacctaaaa atcatttcta tctggtacct gtctctgact
    63541 ttatctaaaa gacaaaacag tgtacaaaaa gattttcttg ggactgtgaa acgtccactt
    63601 gcaatggtta tcggacttac tgcattagtc gctattcttc ccgattttgg taatgcggca
    63661 gttatctttt tgattatttt ggttctgctt ttagccagcg gagtcaatta tgtgtatact
    63721 ttgattgtag gagtaggagg cttttgtcta agtactttta cgatctggct gatcaatatc
    63781 acaaacggaa agatcttacc cggacgttta cagtatatct ataatcgatt tgctatttac
    63841 caaaatcctt tctcagacga attaaataaa gggcatcaac tagtcaacgg ctactatgcc
    63901 atgttcaacg gaggactatt tggcagggga ttaggtaaca gtatccagaa aaaaggattt
    63961 ttacaagaag cacaaaccga ttttatttat gcaatcgtag tggaagaact gggagtgatt
    64021 atggggattt tgatattagc gttgctattc tttatgattg tgcgcattgt ccttgtaggt
    64081 atccgttcaa aagatccgtt caattcgctt ttgtgcattg ggatcggcgc aatgtttttg
    64141 atccaagtat ttgtcaatct tggagggatt actggcgtta ttcctttgac agggatcacg
    64201 ttcccatttt taagtcaagg aggctccagt ttgctgatgc tttcgatttg tgtcggcttt
    64261 gtcctcaaca tcagtgcgga tgaaaaacgc aagagcttag gtttataata aaaaaagatg
    64321 taggagtggt tcgatgaaaa aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt
    64381 atttcgtgct tgtacagaat taggaattaa aactgttgga atctatgcag aagaagatga
    64441 atattccgta caccgtttca aagcggatga agcatattta gtaggacaag gaaaaaaacc
    64501 gattgatgcg tatctagata ttgaagggat catttctatc gcgaaagaat gcggagctga
    64561 cgctattcat ccgggttacg gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga
    64621 agaagaaggc atcatttttg ttggacccaa actgcatcat ttagatattt ttggagataa
    64681 aatcaaagca aaagctgcag ctatcgaagc ggggattgct tcgattccag gcacagatgg
    64741 accaatcgct tctatagacg atgccttgga gtttgcgaaa caatacggtt atccgattat
    64801 gatcaaggca gctctaggcg gcggcggacg cggcatgcgt gtagctcacg atgaaaagag
    64861 tgcaagagag ggctacgaac gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga
    64921 agtgtatgtt gaaaaataca tcgctaatcc taagcatatc gaagtacaga ttctcgggga
    64981 tacgcatgga aacgtcatcc atctttttga aagagattgt tctgttcagc gccgtcacca
    65041 aaaagtagta gaagtagcgc cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg
    65101 ccaggcagct gtccaattga tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt
    65161 tcttgttgaa ggagatgatt tttactttat cgaagtcaac cctcgcgtcc aagtggaaca
    65221 tacgatcaca gaaatgatta cagatattga tatcgtaaca acgcaactgt tgattgctca
    65281 aggtttggat ctgcataaag aaatcggatt gcctcagcaa gaaggaatta aattaaatgg
    65341 ttcagccatt caatgccgaa tcactacaga agacccgttg aataactttt taccagacac
    65401 agggaaaatc gatacgtatc gttcacctgg tggttttggc gtacgtctgg atgtcggaaa
    65461 tgcttacgcg ggctatgtag tgacaccgta ttttgattca ttgctagtaa aagtatgtac
    65521 gcatggtgct acctttgaaa cagccattca gaaaatggaa cgttgcttga aagaatttag
    65581 aatccgtgga gtgaaaacaa acattccatt tatgctcaat gtcatcacac atcctgaatt
    65641 ccaatcagga aatgcaaaaa caaccttcat tgatagtaca gcaacattat ttgaatttcc
    65701 tcgactacga gaccgcggaa acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg
    65761 ttttccaggt atcgaaagtg gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga
    65821 tctaatcaca agaactgatt acgtaacggc taagaatgta ttagatgcga agggtgccga
    65881 tgctttggtc gaatggatca aaggacagga aaatttgttg ttgacggata cgacatttag
    65941 agacgcccat caaagtctgc tagcaactcg tgttcggaca aaggatttca agcagattgc
    66001 acgtttgact ggagaaggtc ttcctgaact cttttcaagt gagatgtggg ggggagcaac
    66061 atttgatgtg gcttaccgct ttttgaatga agatccttgg caacggttga gaaaaattcg
    66121 ttctttaatg cctaatacgt tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta
    66181 ttctaattat cctgacaatg tattggtgga atttgtcaaa gaagcagcag cgcaaggaat
    66241 cgatgtattt cgaatctttg atagtttgaa ctggactcca caaatggaaa aaagtatcca
    66301 agctgtacgg gatactggta aaatcgcaga ggcagctatt tgctatactg gcgatatcaa
    66361 cgatccaagt cgggcaaaat acaatgttca gtattataaa gacatggcaa aggaactaga
    66421 acaactgggt gcgcatatca ttgcaatcaa agatatggct gggctgctta aaccgcaggc
    66481 agcttatcgt ttgattagtg aattgaaaga aacgacagat ctgccaatcc atctgcatac
    66541 tcatgatacc agcgggaatg gaatcatcac ttattctgct gcttcaaaag caggagtaga
    66601 catcgttgac gtggcaatga gtgcaatgag tgggaatact agtcagccta gcatgagcag
    66661 cttgtattat gcactggtca atggtccacg gctgccagaa atcacgattg aaaatgcaca
    66721 gaaattaaac cattattggg aagatgtgcg catgtattac aaaccgtttg aaaacggctt
    66781 gaatgctcct gaaacagaag tatatatgca tgaaatgcca ggaggacagt attcgaatct
    66841 acagcaacag gcaaaagctg tcggattagg tcatcgctgg gatgaaatca aacaaatgta
    66901 tcatactgtc aacttgatgt ttggcgatat cgttaaagta actccatcat ctaaagtagt
    66961 tggagatatg gcactattta tggtccaaaa tgatcttaca gaagaagata tttatgaaaa
    67021 aggcgaaaca ctaagtttcc ctgaatctgt tgtgactttc ttccaaggag aactagggca
    67081 acccgttggc ggatttccta aaaaattgca aaagattatt cttaaaggca gacctgcatt
    67141 gaatgaacgt ccaggtcttt tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt
    67201 ggcagaaaaa attggctatg aaccaaaaca agacgaagta ttaagctatt tgatgtatcc
    67261 gcaagtcttt ttggactatc aaaaagcata taatcaattt ggcgatgtta cattactgga
    67321 cacaccaaca tttttccaag gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg
    67381 cggaaaaacg cttatcattc gtttagatga aatcggagaa cccgatatcg aagggaatcg
    67441 cgtactgttc ttcaatttga atggacaaag acgtgaaatc actatcaaag ataattcgat
    67501 catcagtacg gtccaaaccc gattgaaagc tgaaccgaca aaccgagaac aaattggagc
    67561 aacgatgtct ggttctgttt tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg
    67621 tgatacgttg atgattactg aagcgatgaa aatggaaacg gccatcgaag cacgttttga
    67681 cggagaagtc gcacatgtat atgtgtcttc aggagacact atttcgcctg gtgacctttt
    67741 gattgaagtg actgagaaat aataagcgaa aggtggggaa acatgaaaag actgggtttg
    67801 ttttggctga ttctgctatt agttattgtg gcattctaca tggaaccagt cttgtttccg
    67861 ccaaaacttg aagtgaagga aaactctgat caacaaatat caaaccaaat gacaacgtgg
    67921 aaataccagg agcttaaagc aactggtttt tctacttata tcggaaaacc gatcgatcag
    67981 ctggaaaagg attttggcca agcctatgat cgattaacta gcggatttgg ttttgaaaca
    68041 agatattatg aaaataaagc tagtcatctc acatttgaag cgaacatcca agacagcaga
    68101 gtcacaactg ttaaagtact gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg
    68161 atgacgatgc aagatcttac gaaaatcact actatctata ctaatttcac ttttgagtac
    68221 catgatacag aagttggaat cgaactaatg gaagaggata tgaattatcg tccgctaatt
    68281 gcttttgata acgacacttt tgctatttta ttttttgatc aaacaacaaa cggcctattt
    68341 tcagttgtgt atttagataa agatagtctt ttgaaactat tgccatatca agtgtttggt
    68401 gaaggccttc cacattatca agcagataaa tcggctgatt gggaatcaat caatcgcgtt
    68461 aaagaacgaa aaagtacgac tttattaaat atgcttagaa gagaagacga acttcccata
    68521 tacaatcaaa cacttgcctt tcaaaaccac agtcagctgc tactacatga ttttttgaca
    68581 aggcctgagg aaatattgtc agaggaacgt atggctgatt ggcaaaaatc gctaggcagt
    68641 gctcaaacga cagtgaaatt ctcactgacg aatgatgaat tggagaagtt aatcagtaaa
    68701 caaaaattag aaaatactag tgggctattt attcatccgg cgattgacgc tactttttcg
    68761 tttttatatt ggtacagcga tccttacaac catgaccgtt tcatggaccc gggaacggat
    68821 tctgtaggca ttgctttttc taaagaaaat atgttagtct tattgcaaga agaaaacgga
    68881 gaaagtagtg atagcagtga tcgttaacga agagctgttt caactggagg atcaatgcct
    68941 ccaagtcgct gaaatgataa aaaagagtaa aacgatggct tcttatcttg aacataaaca
    69001 gtcaatggaa gaatctgcaa aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga
    69061 agcatttgaa aatgtagcgg catatggtga gtatgcacct gattatcgtg aaaaaaaacg
    69121 agctgttcga aaagcaaaaa gacagcttga tatggatgag catgttgcag ctttccgata
    69181 tagtgaaaca cagctgcaaa gtctgttgga tcaaattgtc caagtacttg ccgaagaagt
    69241 ttctaatgaa atcaaagtag atgcaggtag cccgtttttt gaaacgaaaa aacactttgg
    69301 atgcggaggt aattgtcatg caattagaca atagtgaatt tgaaataaca aaacgacgcg
    69361 ggctgatcgt atgggtctac agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt
    69421 tgcattatgt ctcaagaaga atgaaatatg tcgtgcttta cttaaatgaa gagacattgg
    69481 aagaaacaga agaacgaatc cgtaaattac attttgttcg aaacgtagaa cgttcttacc
    69541 gaccggatat cgaaatgaat tttgccgaaa aaataggaaa caaaacagta ttaaaagacg
    69601 aaggtttcga aattgaagag ctaaatacag aaatccgatt agctgaacat ctttaaaaat
    69661 ctcttatgag cagtttttaa ataaaaaata acttggataa cgatcgattt ttgatcattg
    69721 tccaagtatt tttttggtat actagtacca gtaccatttc taaggagtga gtagatgcgg
    69781 ataatatcag gaaattatgg cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga
    69841 ccaactacag ataaagtaaa agaatccata ttcaatatga ttggaccata ttttgatgga
    69901 gagacagtat tggatctgtt tgcaggaagc ggtggtttag ctatcgaagc agtatctaga
    69961 ggctgcagtc atgcggtatg cgtagacaaa aattaccaag cgctaaaaat catcaaagaa
    70021 aacatcgaaa ttacgaaaga accagagaaa tttaccacaa taaaacttga tgcggacaaa
    70081 gcaatcgaac ggctagcagc ggagaaacaa caattcgact acttgtttct tgatccgcca
    70141 tatgcaaaac aaaaaataat cgatcaaatc cataaaatgg aagaactggg acttttttct
    70201 aaaaccgcag ttatcgtatg cgaaacggat aaaacagtcg aattgccaga aactgtggct
    70261 ggattccatc aaataagaaa acagatttat ggcataacgg ccgtaactat ctatagaaaa
    70321 gagggaaatc aatgaaacgt gcattattcc caggaagttt tgatcctttt acaaaaggtc
    70381 acttagatac ggtggaacgt gcggctaaat tattcgatga ggtagtaatt ggtgttttta
    70441 tcaatacttc aaagaaaagt ttgtttcccc cagaagaaag aatgacattg atcacaaaag
    70501 ctgtttctca tcttcctaat gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa
    70561 cagcaaaaga gattggtgca gatgcgttga tcagaggcat acgaagtatc aaagactttg
    70621 aatatgaacg agagattgct cagatgaatc atcatctata tgatgaattg gaaactgtct
    70681 tcttattagc aaaaccagaa tatagtcacg tgagttccag tattttaaaa gaagtactgc
    70741 actttggcgg agatgtgagc agctacttac cgccagtgat caacgaagct ttagctggaa
    70801 agcgtgaatc aaatgaaagc taaacaatgg ttgaaaacag tactgattat catatttgga
    70861 atgttgatca ttggatttgt agtagttccc ttgccgtatt atgtagaatc accgggagcc
    70921 acgatcgatc tgaaagaact aattacggtc aatgataagg aagataaagg ttctgggtct
    70981 ttctctctta cctctgttgg tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa
    71041 atgacccctt ttgaagaatt gatcagtgaa gaagaattga ctggtggggc gacaaatgaa
    71101 gaatataatc aaatgcaaca gtattatatg gattcttccc aaaatgcagc aatcgaacaa
    71161 gcgttaaaac ttgcagacaa gccttataaa atggaattca aaggcgtata tgtcatgagt
    71221 gtagagaaaa catcgaattt ctttggcaag ctttcagttg gagatacagt aacaaaagta
    71281 gacgggaaaa gctttcaaag tacagaagca tttatggatt atgtaaaaag ccaaaaagtt
    71341 ggacaaacaa tcgaaatcag ttatttgcat aatggtgaag aaaaaacagc ttctggtgat
    71401 ctgatcgagt taccaacaga taaaaaggca ggaataggta tcacgcttac tgaccatacc
    71461 gagatcgaat cagatacaga tgttcgtatt aattctggct ctatcggtgg gccatcagcg
    71521 ggattgatgt tcactttaga aatctatgaa caagtcactg gtaaaaactt gcgacatggt
    71581 aagcaaattg caggaactgg aacgatcaac agtgaaggag aagttggccg aatcggagga
    71641 atcgataaaa aagtggcaag tgcggataaa gctggcgtag agattttctt tgcaccagat
    71701 gatacgattt cagacgatgt taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa
    71761 gcaaaagctg ccgctaaaaa attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta
    71821 caagaagcgc ttgactatct agagaaaatg aaatgaaact aaataattaa agaggggttg
    71881 tgacacgagt tctgtcacaa cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa
    71941 acaaaagaaa aaattgacgt aattagatgt tgaagggacg attttgccag agctcactgt
    72001 ttcttcaatt ttaaatgaaa ggagtaatga atgattttta ctggtcattc tttgaaaaaa
    72061 gaacaatgat agaaaaaatc agcaagaaaa tactagcttc acccaaattg atcatttgga
    72121 tgtctatgat agttcttatc ttttgtatcg caagtggttt tttattatca aatttgctat
    72181 tttatagaga aacagaagag actgctgcaa aagaaatact ttcttcgttt agttccagtg
    72241 gagaagatcc atcagctgaa ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt
    72301 acaccgatat caaaggaagt gtgaaggagc ctggtatcta ttccttttct tcagaagaac
    72361 gggtctatga tgtactaaag cgtgcaggtg gattattaga agaagcggat agcgatcgaa
    72421 tcaacttttc tgcgaagata gaagatcagc aagtcctata tatccctgct gtaggtgaag
    72481 agctgccaga acatcttgat cagttggcat cctcggaagg aaaacagcct acagcagatt
    72541 ccgagcctcc caaaataaat atcaatacag ccactccatc agaacttcag cagattcctg
    72601 ggatcggatc agtcaaagcg caagaaatca ttcgatttag agaagaaaac ggatccttcc
    72661 agaaagtgga agacctgcag gagatttctg gtatcggtga aaagacagtt gaaaaactaa
    72721 aaaacttcgt tacaattaaa tagaatgatt caaaatcgac tggcacgagc aataaatgga
    72781 cgctaatgga tactaagaat aatccaattc taagagcttg gcaggacgag gaggtagtat
    72841 ttttggatag gaaatagctt gattgttcgc aaagaaacat taaaaaaacc aatgctgaat
    72901 gtctatctcc aaaataaaat atctgggatt catattatga atacggctgt cagcggcaat
    72961 aacagtcaag ctctacgaga acgctttgcc aaagatgtac ttagctatac agcagataaa
    73021 gtatttattc tcattgggac gaatgatcta gcagagcata aacaactttc taaagaaacg
    73081 taccaaaaaa tctgcagtgg atgatagttc agctgaaaaa agactatagt tctgatcatg
    73141 ctttctttat cacgccacca gcagtcgatg agacaaaaca aaaatatcgg aataacaagt
    73201 tgatcaaaga atatatctct gttctcacag aagtagcaaa acgccatgat tgtgaagtat
    73261 cgatttttat acggaatttc ttgaacaaat ggattcgaag aatttttata atgggctaat
    73321 ggatgacgga cttcatttcg gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg
    73381 ttatatttaa agaatatttt gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg
    73441 gaggaatata aaacatgtta gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag
    73501 ttactgataa gtcacataat gaacgcattc cttgggacca gtactttatg gctcaggcag
    73561 tactgttatc tttacgtagt acgtgtacac gtttagaagt aggagcgaca ctcgttcgag
    73621 aaaaaaggat cattgctggc ggctataatg gagcagtcag tggagatgtc cactgcatag
    73681 atgaagggtg ttacgtcgtg gatggacact gcttgcgaac gatccatgca gagatgaatg
    73741 cactcctaca gtgtgcaaaa cttggtatcc cgacggaagg ttcagaaatc tatgtcacac
    73801 attttccatg tttggcctgt acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt
    73861 atctccatga ctatcgaaat gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat
    73921 ctgtacacca agttgcttta gactcacagc atttttcaaa acttcaaaat gaattaacag
    73981 gaaaacatgt ctagcgtttt agaaaggcat gttcgaaatc ggttgatttt tccggcaatt
    74041 acgtcgatga ttatctgttt gttgtattac actgacaatt ggggttatcg tttgcttctt
    74101 gccggaattt ttttatggtt ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt
    74161 ttgtgtagca taacggtatc catttcttat aggctacaag agtattcatt tttagaggaa
    74221 aaaacaacat ctgcgcaaat tactgtattt acagatacga ttcgtgcaaa tggtaatttt
    74281 ttgacaatgg aaggaaggtt atcagagaat aaacaaaagc tccagctttc ttatcaagta
    74341 aacacagaag cagaattgaa aacatggctt aacttccgag gaaagggaat agaattgact
    74401 gctgaaggcg agttcatctc tccagcaaaa aagcggaatc tttataattt tgaccaagaa
    74461 gcttacttca ggaaccatag aatttctgga cggttccaaa ttcaaaagat tgaacagatc
    74521 accatgcaaa atcactggcg aaactggctt cagagaaaaa gaggatcttt tatctccttt
    74581 gtccaatctg aatttccgca aaaaacaagt gtatatatta attctttatt atggggctat
    74641 aaagatgcag gattcagaga accagaagaa atttttaggg agagtggttt gctgcatctg
    74701 ttcagtctat cgggtctaca catccaattt tatttagggt ggctgtatta tttatttcga
    74761 cgtatcggat ggccactaca cgtcagtatt attccgttga gtctactaac tatctgttat
    74821 gtttctattg caggaagttc tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga
    74881 ttgctagtca aattgctgaa taagcattat tccaccatgg acttatttgc agttgtcttt
    74941 tggcttcttt tactatttga tcctcgattt ctttttcatg cgggtggaca gcttagtttt
    75001 ttcatgagtt ttttgtttat cctgatttct tttgatggag attggttgaa aaaaacggcc
    75061 tctcacgtcc tgtttactat gatcacgatg ccgttgattg tatggcattt ttatgagtgg
    75121 cctattttag gtagtctttt tacattactg attgcaccgg tattcaagtt tctttttctt
    75181 cctggtgtgt tatttctcac actcttcaat cgctggctgc cggaaacttt acttttgctg
    75241 atagaagagg gattaatctt atttgagcga ataatcgatt tttcttcagg gtcgtctctc
    75301 attataggac gtttgcccct tgtgctatct gggatgtata ttttcggatt actgatttgt
    75361 atggataggt tgaaagaaca acctgtgaaa cacttgtttt atgttggtct tttttctttt
    75421 atttttttga ctttgccatt tttacgcttt tcttcaacga tcgcttttat cgatgtcggt
    75481 caaggagaca gtatcttttt gcaaagtcct tttcgaaaag aaacgatttt gatcgatact
    75541 ggaggtcagt tacactttga aagagaaaag tgggcgcaag gtatgatacg tcctcctgct
    75601 gaaagaaata tcgttccata tctaaaaggt caggggataa gtgtaatcga taaactcatc
    75661 ttgacacacg acgatacgga tcatgtggga gaattaccca cgttatctca gcattttact
    75721 atcaaaaaaa tttatatcgg ttggggcgct ggacgaaatg agccattaca aaggcattta
    75781 tctgaagctc aaaaaaatgg tactgagatc attgaaatca aacatgggga caggatcagc
    75841 ggttattatg atctttatgt attgactcct tttgaaaagg gagagggaag aaatgaagat
    75901 tcgattggtc tatggatgga atataacaat aggcgctttt tatttttagg agatttgaat
    75961 caagcaatgg aaaaacaatt gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa
    76021 ttaggtcatc acggtagccg tacgtcaagt aacacagatt ttctttccca tattgaagca
    76081 aaacatggga ttatatcctg cggcgtaaat aatcgttatg gtcacccgca cagcgaagta
    76141 ttggagacac tagaagaaaa tcagataaaa acatggcgaa cggatcaaca aggaatgatc
    76201 acctatcgct ggcatccagt ttttcatcct catgggctag tggaaacaat gatagactag
    76261 taattctcat ctgctcatgg taggataatt tttgaaagtg gtgagtaatt tgagtataca
    76321 agcagagtta caaaaaatac gtaaagaaaa acttgcatct tgttacttga ttttaggaac
    76381 agaaaagttt ctccaagatc aagttcggac agaaattgtc aaaaaaatcc aattagaggg
    76441 cgaagatgac ttaaattttt taagttttga catggaaaat gcaagtttag atgaggtagt
    76501 agctgaagca gagacgttgc cgtttttcgg agatcaacgg ttagtattcg tagagaatcc
    76561 ttatttttta acaggtgaaa aagtaaacaa tggaatcgaa caaaatactg atttattgac
    76621 ggcttatttg aaagaaccat tagaatcgac tgtattagta ttctttgcgc catatgaaaa
    76681 gttggatgaa cggaaaaaag taacgaaaca attgaaaaaa acagcaatta tcatcaatgt
    76741 ccaacagttg aatgaaaaag aagtacgtca atatctgatg aataccttag agaattcctc
    76801 aatcaaaatg gaacgaagtg caattgattt attcttgagg ttgaccgact tagatttatc
    76861 caaaatgatg agagagttac agaaattggt cctttatgga caaaatcaac agcaaatcac
    76921 ggtaagagaa gtagaagaat tagttcctaa aacgttagaa cataatattt ttgacatgac
    76981 ccaatatatt ttaaaaggga agacggaaca agctttgcgt ttatacgaag atttagttat
    77041 gcaaggggaa gaaacaatca aaattaatgc gattttgctt tctcaattac gtttattttt
    77101 acagacaaaa tttcttgtaa agattggtta tcagcaggca aatattgctg aaacattgaa
    77161 aatccatcca tatcgtgtaa aacttgccat gcaggaagta aaaaaattcg atgaacattt
    77221 gctggtacag ttgtttgatc aattagttga gatggattat caaatcaaaa cgggacaaat
    77281 cgaaaaagaa ttaagttttc aactattcgt tttgcgcaca gggcagttgt taagaaatcg
    77341 ataagaagaa agacgagggc aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg
    77401 acaaataaaa aaatcggccg aagccgattc ttttatttag cgattttttt gcttaaacga
    77461 gatttgtcgc ggttagcttt gtttttgtgg attagacctt ttgattcagc catatcaata
    77521 gctttaacag cttctttata taacgcatct acgttgtcag cacctgaagc tacagcatct
    77581 tcaaattttt tgattgcagt acgcatagcg cttgtttgag atgaattttt cacattagcg
    77641 ttttcgcttg tacgaacacg tttgattgca gattcaatgt ttggcattag tttcacctcc
    77701 gataacttaa gttcttacgc gtgttaccgc ataattcaac attcattatt atacctaaag
    77761 gcagcgtgct ttgcaatatg aacatgacaa gtttttttcc ttaacagtct tttattagga
    77821 ttttttttca gtaaaaacgg atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg
    77881 gaggcaatag cgtcaaacca aactagattt ttatttatct atttaaacaa agtttgaatg
    77941 ggaatgtttg gtactaagtt attatataac aaagagaacc gtttgcaaag ttttttttga
    78001 aaagggatac gattccctgt tgttctttgt ttttctatta agaaactgca gttattttat
    78061 aaccagtatc ctttgatcag taaaggcatt ctggtgtacc gattatttta atgtattcat
    78121 cgatattttt tatcaacatt ttttttatga ccaactggtt ccgacggttc catttgccac
    78181 ttacttccag cacatattta tttaggggca aacgtaagat atattttgcc aaatagcgat
    78241 ctttaagcag gccattgatc acacggtcct caagctgcaa gttgatccca gtcagcatca
    78301 ttggctgttc ttgtaaaacg tacgtatcaa ttaaaagacc ttcaaaagtt tccacaagcg
    78361 tcttcctttc ttttcaaagt aacctgaaaa caggcactaa ttcttccatt ttgatattcg
    78421 ttgaagtgga tgcgatcatt ctttcttttg tccactgtaa tctagtataa caaaaaagag
    78481 cagaagagcc aaaaagaaaa aagagcatcg aattctatag gaagtctcat tggcacggcc
    78541 taaattatta caaaacattg attaaaaaaa gcccctgcat cgcaggagca tcccctatat
    78601 cgttttaata ggtcaatcaa aaagcagtat caaacacatt ttgtatcaaa tcaggaaata
    78661 atagataagc taagcccaga atcaaaagta ccgctagaag aaaccagccg attgttccta
    78721 tgaaatactt taatttttcg aacattgtat cacctcgttg tcagtatatc acggatcagt
    78781 aaattggggg tgttaagaat ctcctaaaat agacaaaatt tgttctattt tcctaaagca
    78841 aatacttgta agatacagta agtgatacca gaagcaatga ccggtccggc ggcgattcct
    78901 cttaagaaga caacacctaa aatcgtgccg aaaacaagtg caacagtgat ttgtggatca
    78961 gaagcaatca atcctacacc cttggaagat aagacagcca ctagcccacc gcaaaaaaca
    79021 gctacccagc caatagggga tttaaaggct tctaatagat cacgtagacc gatttctcct
    79081 gttgcgatag ggattagaat agccgctgtg atgatcgtca ccccaatatt gattcctttg
    79141 ccttgaagcc aagggaaaaa ggaacgggag gctggtatga gcttcataat caaaacaaaa
    79201 gctgccgcta tcatcagact ttgattttta gctaaaattg ctacaagtaa aataattcct
    79261 aaaaaaagcc aactttccat gaaatatatt cctcactttc ttcgaaacaa tcataacatg
    79321 tttttagaaa gttacaaaag taggaattca tccttcaaga cctattcata agctgttttt
    79381 ttcataaaat aaacaaaatc ataaaaaaac actttgctta tttgacagaa gacagccgcg
    79441 ctttgtatag tggacaagac ttacattttt ttgaagaatc agaaagatca ggtaaaggtc
    79501 ttagtaaacg caagccattc agaataacca atattgtgct tccttcgtgt cctacaactc
    79561 caagaggtag atttaaaaat tgcaggaagt tagaagcaat caacaagaga ataacaagaa
    79621 tcgaaaaaat aatattttgt ttgatgatcc gccgcatttt taaagatagc cgatgactgt
    79681 agacaaattt atttaagtcg cttttcatta agacgatgtc tgcgatatcc atagcggcat
    79741 ctgtcccttg ccccatagcg acacctaaag aagcggctgc taaagcaggc gcatcattga
    79801 ctccatcacc aaccatcgca tttacttggt aaagttcatt ctcttttttg actagttgtg
    79861 ttttttcttc cggagtacag cttgcatagt aatgttcaat ccctacttgt tcagcaatgg
    79921 cctttgctgt gccagaatgg tcgccggtta tcatacttgt atggatgttt tgggatttaa
    79981 agtaggaaat tacttgttgg gtatttgctt ttggaatatc tagcagacct aaaacagcaa
    80041 ttaactgctg atctttagaa agataaatca cggttttgcc ttgattttcc aaacgttcga
    80101 tcatttccgc aatctctttg ctgattatca tcgtctcagg atcatatgcg tgcttgccaa
    80161 ctttccattg cgcacctaaa taggtagttt gtaatccaaa accagtaatt tcttctattg
    80221 gtaagtattg gatttcttca ggtattgtgc aatcgaaata ttgcaaaatc gcatgagcaa
    80281 gtggatgcgt cgttttttgt tccatagcaa caagaagttg ttgtgccaaa tccttttcat
    80341 caaagaaaaa gctgtcagtt acaactggtt ttcctttagt gagcgttcct gttttatcaa
    80401 aggcaatcgc ttttaattca gaaagctttt ctaaatggat accgcctttg attaaaatcc
    80461 cattttttgc agaatttgaa agagcagcta gagaagctgg tgtagcagat gcgacaagcg
    80521 cacaaggaga agccacaact aataatacca ttcctcgata aaagctttca tcccaactcc
    80581 aacctaggaa aaagtggggg agaaggatca ttagaggaac agcaagcaaa atcaatttta
    80641 cataattatt ttcgattcgt tcgataaatg aagctgtttg agttggcgta ttctgcgctt
    80701 cttctactaa ttggataatc ttagcaaaga cagtttcgga actcgttttt gttactcgaa
    80761 tcgtgatggg atttccttga ttcagcgttc ctgcatacat ctcatcgcct aaatattttt
    80821 ctacaggcac agattcaccg cttaatgcag actcatcgat cgttgcctgt gtgctttcta
    80881 aaaagccatc tatcggaaca gctgctcctt tagcgacaaa taccaagtta tccaccttta
    80941 gttgagaaac atctacttct tgcatttgtc cattttcttt taataattgg gctttttgtg
    81001 gttgaagatt catcaaagca gtaatttctt tttgactttt attagttgtg tattcctcta
    81061 atgcaccgct taaacaaaag atgaatgtca acattgctcc ttcaaagtaa ttaccgatca
    81121 aacaggcacc aatagcagct aaagccatca ataaatccac attcagtgtc cgatcattcc
    81181 acaattcttt caagccttcc gatgtttgtt tatatccacc gatgataatg gcactgatat
    81241 aaaaaagtgg ggtgatggta agagagaatc ggtcgaagat aaaaccgaag atcataaata
    81301 aaaggcagcc gattgttgct gcaaaagctt ttttctgatt agtcatcgtt attagacctc
    81361 cttgtcaaaa caaggatagc ataataaaaa tgtaattgat aataataaca gctaaatgag
    81421 aacgataatg gttatcattt ggtgattaag cttgatgttg tttttattat ttataatgat
    81481 tattattaaa gaaaataaaa aaccagaaca tttctcaaat aagagaagtg ttctggtttt
    81541 ttctacattg caataaacca ataaccaatc aaaatgatac caaggataat acgataccag
    81601 ccaaaagcgg taaagtcgtt tttcttcaaa tagcttagta agaatttgat agctaagacg
    81661 gaaaccacaa aagatacgaa tgttcctaca agaagaacaa cagtttcttc cattttgaat
    81721 gaattccctt cagctaaata tttgacgatc ttcaagccgc ttgcgccaaa catgacagga
    81781 atccctaaga aaaatgaaaa ctctgtagcg acaaaacgcg aagcaccaat caagatagat
    81841 cctaggatcg ttgcgccaga acgggatgtt ccgggaacaa gtgccaagac ttggaataac
    81901 ccaacaagaa gagctgcttg gtacgtaaag tcattcagag aagtccaacg aggtgttttg
    81961 tttttgttgc gtttttcgac aataataaag gcaataccgt aaacgatcaa aacaatggca
    82021 actggtaaga acttgtggaa atttgcttct aaccaatcat ccaaaggcaa accaatgatg
    82081 atggctggta tgcaagcaac gatcacttta aaccaaagtg tccacgtatc ttttttttct
    82141 accgttgatt tacttggaga aaatgggttt aacttgtgaa aataaagaac gacgacagcc
    82201 aagatcgccc ctaattggat aacgacattg aacatcgaca taaattgtga actggcatcc
    82261 agtttgatga attcatctgc taggatcaaa tgaccagtac tactgatggg cagccattcc
    82321 gttattcctt caataatacc gagaatcact gctttgataa tatttgcaaa aaacataaat
    82381 tccttccttc ccaattaaga tacatcttat agtataccgt tattttttga gaaacccaat
    82441 ctgtttttta atattaagaa aaacttgaga aataaagcag ataagtacac gaagagaaaa
    82501 aagaagacaa agccctcgtt cagactttgc cttttatgat tctctggtaa aaattaaaat
    82561 atccccatta tagaaacgag tcgcgactat gtgttttccc gttatcgata taagacgtat
    82621 cattgatgcc gtggatagaa aatcgaccgt ttgcataagt gacctttgtt acgctgccat
    82681 ttaaaagccc agcacgaaca ggctgtttag gatcgatcag attaagcaaa aaggcgatcg
    82741 tcaaaccatg agatacgact aaaacatttc caccaccatt tttttcgcag tgatgggcga
    82801 tatcttcaaa tcctgtccat acacggtctc gcaatgtttc ataagtttcc gcccacccag
    82861 cggtatctaa gttgtataca gcattagcaa tttgttcaaa agaaacttct gtggtaaaca
    82921 tttcatcata tgttttaaaa ttcaatacac gagggatcac accccacatt tccatgtcat
    82981 atccaccttc aagagacccg aaacaccatt ctctaatcct tttttcaata aaataaggaa
    83041 tttcttttcc cttagaatgt tctcctagaa taatacgggc agtttcgatt gcacgaccac
    83101 tgtcactaga ataagcaaat gaaaagtcga cattttttaa cccgcgacct aaataatgaa
    83161 tgccttcttg tccttgcttt gtgaggggtg tatcacacca gccttgtact cgttcaattg
    83221 tattgaacat cgtttttccg tgtcgtacga tataaagtgt agtttctgtc attttattct
    83281 cctcctaagt cgttttaacg attgaaaaaa ggatttgtcc ttttttcctg ttcaatcgtc
    83341 gttgcatcgc catgtcctgg atagactgca aattcatcag gtaatacaaa cagctgggtc
    83401 cgaatactat gaagtaattg ttctaaattc cctgtataca gatcggttct accgatactt
    83461 cctctaaaca gggcgtcgcc agaaacgaca aaatcatcaa aaataaagct gacgcttcct
    83521 atagaatgcc ctggggtagg gacgacgcga aaagacatgt ttcctaaagt ataagttttc
    83581 atttcaaatt catattctgc aggcgagaca ataacatcag caatatcatc atgtctaccg
    83641 agtccagaaa gattcaaaat cggatcacct agccattttt gctctagtgg gctgacataa
    83701 actgggattt gataatacgc gcgtaaaggt tccactgcac cgatatgatc gtagtgagta
    83761 tgggtaagca aaatcgctac cggctgttgg tttgtttttt tgatttcttg tttgattcgt
    83821 tccgcatctt ctccagggtc aatgatcaaa agtgcttctt cgttgtagac caaataacag
    83881 ttttcttcaa tcattcctgt ttttaatctt tcgatatgca tgtgcattcc tccttgatag
    83941 ccaaaacttc tttcatccat tagtataacg cattcattgc taggaaacaa aaacaggtac
    84001 ttatttctct ttacttatct gaattatcag actatatgaa aagtatttgg atattctaaa
    84061 gagaaggaaa gtaagttttc atagcatttt aatatgtcct tgttacatta gattcatcca
    84121 aaaatccaaa ttctatatcc tatatccctg cctaatcagc agggtgtttt tttatgtttg
    84181 gaaagagagc tctttttgct aaactaggtt ttttcaggta atcttagaga gaaagaggtg
    84241 gtggaaatga tcaaacagtc aaaaatatct gtgcggcact tagtagaatt tattttgcga
    84301 cgtggaagta tcgacaatcg taaaaaaagt aaccatactg cattagaagg agcgagaatc
    84361 caccgcaagc tccaaaaaga tgcgggagaa aactatgaaa aagaagtctt tttaaaaaca
    84421 acagttcaat tagatgaata ttacctgatc gttgaaggcc gtgcagacgg tattttcaaa
    84481 agagacggta tttattatat agatgaaatc aaaacctccg aaccacgatt tgaagattta
    84541 gaaccagaac aagtggaact tttctttcat caagcaaggg tgtatgccta tatctatagt
    84601 caagaacatg atttacaaga aataaatctg caattgactt acttccagac ggcagaagaa
    84661 gtgatcacga gaaaggttga acatcagaca agagagcagt tagaaacttt ttttaaaaag
    84721 ctgactgaag attataaaga atggcttgtt tttcaagaaa actggcgcac tgtacgcaat
    84781 gcctctttga tggctttgaa attcccccat gatgagtata ggaaaggtca gcgtgaacta
    84841 gcggtagctg cttataaaac gatccgtacg aaacagaaat tgtttgtaga agcacctacc
    84901 ggaacaggaa aaacaatctc tacgttattc cccgctttga aagctgtagg ggaagaagag
    84961 ggagaaaaga tcttttatct aacggctaaa acaataacta gacaagtagc tgaagatgct
    85021 atgacagcat taaaagatac aggagctgaa gtaaaaagtg tcactttgac ggcgaaagac
    85081 aagatctgct ttttagatga gacgacctgt aatccagatc agtgcccata tgccaatggt
    85141 tattacaatc ggattaatga aggtttatgg gatcttttga atcatgagaa tcagatcact
    85201 cgtgaagtca tcgaaactta tgcaagaaag catacacttt gtcctttcga actatcatta
    85261 gatgtcagta tctggtgtga cgtaatcatt ggggattaca attatttatt tgatccaact
    85321 gtttatttaa gacgtttttt tgaagatgaa aaaaacgagg actatctgtt tttgattgac
    85381 gaagcacata atttggtgaa tcgttcccga gagatgtatt cggcagaact atcttatgaa
    85441 aaaacgaaac gaagtaagga agctatacca aaggaattca aaaaacttca tcgccgtttc
    85501 aacaaactat taaaagaatt tgattcgatc cgagaaatag caaaagaaga tcattgggat
    85561 tatcatcatc aaaaagcacc ggctgaatct ttagtaaagg caggttatca attaagcgaa
    85621 aaaattaaag aatggctggc agaatttcct gagcacccat cacaagaaca attgcttcct
    85681 tattattttg atttgcttca ttttttgaag gtcagtgaat tttatgatga tcactacgaa
    85741 acaacagtcg aaaaaacgta tcgcgatctg atagtaaaag agttttgtat tgatccaagc
    85801 ttgtttcttg agcagtcgtt ggataaagga aaaagcagta ttcttttttc tgctagtttt
    85861 tcaccactct cttattatca ggaaacactg gggggacaaa aaagtctggc ttacaaactg
    85921 ccgagtcctt tcccagaagg aaaccagcaa gttttcatcg caaattacct agagacgact
    85981 tatcgaaaaa gggaacacag tctggcaaaa ttagtagaga cgattcatgc ttttgctgat
    86041 ggaaaggtcg ggaattattt cgttttcttt ccttcttatc aatatttaga tcttgcggtg
    86101 gaagcattca gacagcaata tcccgacagc aatgtgctaa tccaagaaac ggacatgaat
    86161 gaggaagaac gcgaacgatt tttaacaaaa tttcaaacaa atcccgctga aacattgatt
    86221 ggattttgcg tacttggcgg gattttttca gaaggaatcg atttgagagg ggaccgattg
    86281 atcggcagta tgatcgtagg tgtaggtttg ccgcagatga atcatgagca ggaactgatc
    86341 aaatcatatt atgatgagaa ggaacacctt ggatttgctt acgcttatca gcttcctgga
    86401 atgaacaaag tcttgcaagc tggtggtcga gtgattcgtg gcatggcgga tcaaggaatc
    86461 gttgtattgg cagatcaacg attttctagt ttttcttatc gacgtttatt cccacaacat
    86521 tggcaaacag caagagaagt acgaagtgtt ggggaattgg aagaaggaat acagcgtttt
    86581 tggttatcaa aagaagcagt aaatcaaaaa aacgaggaat gacagacgtc agcctcgttt
    86641 tttgattaac gatagttagt gaattgcaac tcgattggta agtcaagttt acgtaataaa
    86701 gcaatcacag cttgtagatc atcacggttc ttacctgtca ctctaatctg atcttcttgg
    86761 atttgtgctt ttactttcag tttttcattt ttgatagctg tagtgatttt cttcgcgttt
    86821 tcacgatcga ttccgttgac caaatcggca gtttgtcgag ctttgccacc tagagcgtgt
    86881 tctgattcgg aaaaatggat atttttgatt ggcacatttc ttttgatcag cttaccaaat
    86941 aatacatctt tgatctgttc gattttgaaa tcatcatcgc tcaatacaac tagattgctg
    87001 ttctctaatt tgatttctac tgtagaatcc ttgaagtcaa agcgattgga caattctttt
    87061 gttgtttgct gaatcgcatt ttttacttct tctgtattga cttctgatac aatgtcgaag
    87121 ctagcatctt ttgccatagg aaccctcctg atatacatat aaatatttac catacatcta
    87181 tcttatcata ggattagggc agattcttac ctgtttgcta aaattcttct catttgagtt
    87241 cgaagtattt tattttaata gataaactgt tattcttaca tttggaatac caaagtaggg
    87301 gagaggtgct tgtgagtaaa attatgactg cgtatcataa aaatgaaaga ttaaagaaaa
    87361 tagtggttat tttgataacc ggattgaccg ctgcggtcgc tttaaattat tttttgattc
    87421 cagccaatgt cttttctgca gggatgaatg ggatcgctca aatcatttcc tcgcttttat
    87481 atgaatggtt tcatatcaag atagacacag gaacatttat ttttcttttg aatatccctg
    87541 tgtttgtatt agggtttctc aaagtaggaa aacgagcaac gatccttagt tttgtgaatg
    87601 ttgtatgtgt atcggtgatg acgatgctgc ttccagtcgg acagatcact gataatattt
    87661 tgatgaatgc cctagtaggc ggtgttttat taggtcttgg cgtaggatta tctttaaaaa
    87721 tgggctttac aactggtggg atggatatca tctctcttgt actttcacaa acaactggaa
    87781 aaacagtcgg aaactacatg ctgattctaa atggtatcat tgtagtcatc gcaggcttct
    87841 tctttaactg ggaaagtgcc ttgtatacga ttatttccat ttatgcaatg actcaagtaa
    87901 ttgatgccat ccacacgagt catcaaaaag taacagcaat gatcgttacc gtcaagccag
    87961 aagaggtaac agaagaacta gcaaaacgga tggtacgtgg aatgacatta ctgccgtctg
    88021 tcggtggcta ttcaaaaaaa caagggaaca tgatcatgat ggtcatcacc cgctacgaaa
    88081 tgtatgatct tgatcagatc gttcatgaaa tcgacgacga tgcatttatc aatattttac
    88141 caactcattc agtatttggc cggtttgcaa atgaaaacga acaaaaaatg tatcgaacaa
    88201 ctggcgtatt gccagaaata aaaaatcgtt cacaaaaaaa atgaggaatc aggtttattt
    88261 tagaataaat ttaatctatt acatctaata agaacatttt tataaattta aacgagaatc
    88321 ttacttctaa attctcattt acaagcagct aaaaaaagag tatgataaat aaaaatcgtg
    88381 ttaaggagtg tcgtacgatg agcgaagcaa accaagaacg gtctggacaa gaaatagaac
    88441 taatcaaaga acgtattctt gctgccttgg aaatggtgat tgatcctgaa ttaggaatcg
    88501 acatcgtcaa tttaggcttg atttatgata tagaattcaa tcctgaaaat ggagaaacag
    88561 tcattaagat gactctaaca actatgggct gtccattagc agatatttta acagaatcta
    88621 tccatgacgc attaaaagaa gtgccagaag taacgaaagc agaagtcaaa ctagtctggt
    88681 atccagcatg gacgacagat aagatgagcc gttatgcacg gattgcgttg gggatacgat
    88741 agaaatcttg gctgactagc tatgagaagc aaataggaaa aacaaaaaag ccttttatcc
    88801 tttctagaag aaaagagata aaaggtttct ttgtttataa aattttgtct gctatattat
    88861 aagttaatta aataaatgtg ttctattgat aaaggacatt caaatccctt tccttttgga
    88921 atccttcttt tttacatcag tttgattttc gtatagtatt ctttctcatc ttcacgataa
    88981 atcgcagccc catttttttg ttgtgcttta agactgccaa gatttttttt atttacagac
    89041 aaaagtgcct catcaatgcc gatttttttt gcctcttgta gtactaatgc taatccttgt
    89101 gtggcatatc cttttttacg ataattaggg gagatgccgt aaccaatatg gccagcgccg
    89161 tttcttaatg tttcgttcag tttatggcgc aaattaaaaa ttcctacata ctcatgttca
    89221 tcactttcta aaataaagac ggttgcggga acgtaactct caggaagatc gattcctaaa
    89281 gacgtttttt cgcatttttt tacataatct aaaaattcag caaatgtata gccataagca
    89341 ttgttgataa atccactctc atttggtcca aagctagttt gtagctgata agctttcttt
    89401 aaatctgctt cccatagttt gatcagtttc atcgtattca cctctttaag taaccttatt
    89461 catttgtttt ctactatagc actattgttg taaatagcca tgcctatttt tatttattgt
    89521 gtcatatcgt attaagaatc atcgaacaat acaaatatga attacaataa aaaaattatt
    89581 tgaagttcgt tcattcgtta cttatgatct ctagaagaaa gaaaacgtga attacttcag
    89641 cgtctagaat tccagaagga tagtaatcaa cagaagaaat aatcaatatc caaatgaaag
    89701 aagatagctg aatcgagaaa aagaggaaaa aagaaatgaa gaaaaaaata aaatagttac
    89761 taatcccaga gtcgttcgtt taacattgaa atcgatcata tggataaaac agattttttc
    89821 accaaccctc aatagatgat ggagttgctc ggatgaatta tttgtgtaga tggcataagg
    89881 gagggcgtac agaaatgaaa aagaacaaaa atatgttctt gacaaaaaac acatgtaatc
    89941 ctaaactaaa agatgtgatg cggctatggc ggaattggca gacgcgctag cttcaggcgc
    90001 tagtgagggt gacctcgtgg aagttcgagt cttcttagcc gcataatttg tttttttata
    90061 aagagaaggt acacctggag cgatgagaaa gaaaataaca tattatctaa aagaatatag
    90121 gaaaaatttt aaacaacgga accagattca aataaatcaa aaaaaatttg tgtgaaggtg
    90181 ggacagttta aaacctaata gattgattca aatagtagat ttatagattc tgatacaaga
    90241 aatactggca aacgatagtt aaggaataaa gactaaactt aaactcaaaa agaggtcatg
    90301 cgaaagaata aatcgcatga cctcttacta tattttgaat gtgtttaaac gttcaaataa
    90361 tgaatcttag taccaaccgt ttgcttccca gaatgctttc gccgcttccc aagaaccata
    90421 acgtgaagta acatattgtt ctgctactct ttcttggttt gcagcagagt agtcaccatt
    90481 taagtaagaa gaatctaatt ggtaacggcc gatgtaacgt ccgttcgttg ctgtgtaaga
    90541 accgcttgat tctttttgtg cgatccattc ttttgcagag cttgtacttg ctggagtagc
    90601 agcagtttct gttacagcag gagcaggttg tgtttcagca acaggcgctg cttgtgtttc
    90661 cgtttgaacc gtttcttgta caacaggttg ttcagcttga acaggttcag cttggactgg
    90721 tgcttcttga acggctgctt gaggttcagc agctgcttgt gcagagcctt ctgttgggat
    90781 tgttaattgt tgtcctgagt a
//
LOCUS       DAZKCW010000003        87763 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000003 DAZKCW010000000
VERSION     DAZKCW010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 87763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.003"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(171..1220)
                     /gene="recA"
                     /locus_tag="ACG84Z_000176"
     CDS             complement(171..1220)
                     /gene="recA"
                     /locus_tag="ACG84Z_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFP9161057.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(1329..2570)
                     /locus_tag="ACG84Z_000177"
     CDS             complement(1329..2570)
                     /locus_tag="ACG84Z_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFP9161058.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(2810..3388)
                     /gene="pgsA"
                     /locus_tag="ACG84Z_000178"
     CDS             complement(2810..3388)
                     /gene="pgsA"
                     /locus_tag="ACG84Z_000178"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFP9161059.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(3597..4520)
                     /locus_tag="ACG84Z_000179"
     CDS             complement(3597..4520)
                     /locus_tag="ACG84Z_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFP9161060.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(5259..6545)
                     /locus_tag="ACG84Z_000180"
     CDS             complement(5259..6545)
                     /locus_tag="ACG84Z_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFP9161061.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(6538..7806)
                     /locus_tag="ACG84Z_000181"
     CDS             complement(6538..7806)
                     /locus_tag="ACG84Z_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFP9161062.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            8058..8519
                     /gene="mscL"
                     /locus_tag="ACG84Z_000182"
     CDS             8058..8519
                     /gene="mscL"
                     /locus_tag="ACG84Z_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFP9161063.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(8578..9024)
                     /locus_tag="ACG84Z_000183"
     CDS             complement(8578..9024)
                     /locus_tag="ACG84Z_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9161064.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(9117..9362)
                     /locus_tag="ACG84Z_000184"
     CDS             complement(9117..9362)
                     /locus_tag="ACG84Z_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFP9161065.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(9477..10055)
                     /locus_tag="ACG84Z_000185"
     CDS             complement(9477..10055)
                     /locus_tag="ACG84Z_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFP9161066.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(10132..10662)
                     /locus_tag="ACG84Z_000186"
     CDS             complement(10132..10662)
                     /locus_tag="ACG84Z_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFP9161067.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(10666..11526)
                     /gene="rlmB"
                     /locus_tag="ACG84Z_000187"
     CDS             complement(10666..11526)
                     /gene="rlmB"
                     /locus_tag="ACG84Z_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFP9161068.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(11519..11914)
                     /locus_tag="ACG84Z_000188"
     CDS             complement(11519..11914)
                     /locus_tag="ACG84Z_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFP9161069.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(11911..13323)
                     /gene="cysS"
                     /locus_tag="ACG84Z_000189"
     CDS             complement(11911..13323)
                     /gene="cysS"
                     /locus_tag="ACG84Z_000189"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFP9161070.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(13320..13856)
                     /gene="epsC"
                     /locus_tag="ACG84Z_000190"
     CDS             complement(13320..13856)
                     /gene="epsC"
                     /locus_tag="ACG84Z_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFP9161071.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(13942..14181)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(14178..15638)
                     /gene="gltX"
                     /locus_tag="ACG84Z_000191"
     CDS             complement(14178..15638)
                     /gene="gltX"
                     /locus_tag="ACG84Z_000191"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFP9161072.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(15808..16965)
                     /locus_tag="ACG84Z_000192"
     CDS             complement(15808..16965)
                     /locus_tag="ACG84Z_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFP9161073.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(16999..18369)
                     /gene="radA"
                     /locus_tag="ACG84Z_000193"
     CDS             complement(16999..18369)
                     /gene="radA"
                     /locus_tag="ACG84Z_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFP9161074.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(18432..18959)
                     /locus_tag="ACG84Z_000194"
     CDS             complement(18432..18959)
                     /locus_tag="ACG84Z_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFP9161075.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            19189..19995
                     /gene="proB"
                     /locus_tag="ACG84Z_000195"
     CDS             19189..19995
                     /gene="proB"
                     /locus_tag="ACG84Z_000195"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFP9161076.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            19992..21239
                     /locus_tag="ACG84Z_000196"
     CDS             19992..21239
                     /locus_tag="ACG84Z_000196"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFP9161077.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            21315..21659
                     /locus_tag="ACG84Z_000197"
     CDS             21315..21659
                     /locus_tag="ACG84Z_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161078.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(21776..22102)
                     /locus_tag="ACG84Z_000198"
     CDS             complement(21776..22102)
                     /locus_tag="ACG84Z_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161079.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(22717..23919)
                     /locus_tag="ACG84Z_000199"
     CDS             complement(22717..23919)
                     /locus_tag="ACG84Z_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9161080.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            24036..24551
                     /locus_tag="ACG84Z_000200"
     CDS             24036..24551
                     /locus_tag="ACG84Z_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFP9161081.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(24750..25196)
                     /locus_tag="ACG84Z_000201"
     CDS             complement(24750..25196)
                     /locus_tag="ACG84Z_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFP9161082.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(25243..26721)
                     /gene="msr(C)"
                     /locus_tag="ACG84Z_000202"
     CDS             complement(25243..26721)
                     /gene="msr(C)"
                     /locus_tag="ACG84Z_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFP9161083.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(27075..27704)
                     /locus_tag="ACG84Z_000203"
     CDS             complement(27075..27704)
                     /locus_tag="ACG84Z_000203"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFP9161084.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(27688..28152)
                     /locus_tag="ACG84Z_000204"
     CDS             complement(27688..28152)
                     /locus_tag="ACG84Z_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9161085.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(28639..29907)
                     /locus_tag="ACG84Z_000205"
     CDS             complement(28639..29907)
                     /locus_tag="ACG84Z_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFP9161086.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(30138..30875)
                     /locus_tag="ACG84Z_000206"
     CDS             complement(30138..30875)
                     /locus_tag="ACG84Z_000206"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFP9161087.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(30942..31511)
                     /locus_tag="ACG84Z_000207"
     CDS             complement(30942..31511)
                     /locus_tag="ACG84Z_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFP9161088.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            31639..32511
                     /locus_tag="ACG84Z_000208"
     CDS             31639..32511
                     /locus_tag="ACG84Z_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9161089.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            32853..33725
                     /locus_tag="ACG84Z_000209"
     CDS             32853..33725
                     /locus_tag="ACG84Z_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFP9161090.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            33722..35680
                     /gene="nagE"
                     /locus_tag="ACG84Z_000210"
     CDS             33722..35680
                     /gene="nagE"
                     /locus_tag="ACG84Z_000210"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFP9161091.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(36012..36863)
                     /locus_tag="ACG84Z_000211"
     CDS             complement(36012..36863)
                     /locus_tag="ACG84Z_000211"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFP9161092.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            36986..37453
                     /locus_tag="ACG84Z_000212"
     CDS             36986..37453
                     /locus_tag="ACG84Z_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFP9161093.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(37716..38198)
                     /locus_tag="ACG84Z_000213"
     CDS             complement(37716..38198)
                     /locus_tag="ACG84Z_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFP9161094.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(38298..39161)
                     /locus_tag="ACG84Z_000214"
     CDS             complement(38298..39161)
                     /locus_tag="ACG84Z_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFP9161095.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            39759..40634
                     /locus_tag="ACG84Z_000215"
     CDS             39759..40634
                     /locus_tag="ACG84Z_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFP9161096.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(40779..40931)
                     /locus_tag="ACG84Z_000216"
                     /pseudo
     CDS             complement(40779..40931)
                     /locus_tag="ACG84Z_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(41199..42530)
                     /locus_tag="ACG84Z_000217"
     CDS             complement(41199..42530)
                     /locus_tag="ACG84Z_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9161097.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(42679..43392)
                     /locus_tag="ACG84Z_000218"
     CDS             complement(42679..43392)
                     /locus_tag="ACG84Z_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9161098.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            43567..44991
                     /locus_tag="ACG84Z_000219"
     CDS             43567..44991
                     /locus_tag="ACG84Z_000219"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9161099.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            45290..45997
                     /locus_tag="ACG84Z_000220"
     CDS             45290..45997
                     /locus_tag="ACG84Z_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFP9161100.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            45984..46307
                     /locus_tag="ACG84Z_000221"
     CDS             45984..46307
                     /locus_tag="ACG84Z_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFP9161101.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(46396..47433)
                     /locus_tag="ACG84Z_000222"
     CDS             complement(46396..47433)
                     /locus_tag="ACG84Z_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFP9161102.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(47754..48737)
                     /locus_tag="ACG84Z_000223"
     CDS             complement(47754..48737)
                     /locus_tag="ACG84Z_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFP9161103.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(49152..49922)
                     /locus_tag="ACG84Z_000224"
     CDS             complement(49152..49922)
                     /locus_tag="ACG84Z_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9161104.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(49915..50850)
                     /locus_tag="ACG84Z_000225"
     CDS             complement(49915..50850)
                     /locus_tag="ACG84Z_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161105.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(51166..52815)
                     /locus_tag="ACG84Z_000226"
     CDS             complement(51166..52815)
                     /locus_tag="ACG84Z_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFP9161106.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(52932..55535)
                     /locus_tag="ACG84Z_000227"
     CDS             complement(52932..55535)
                     /locus_tag="ACG84Z_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFP9161107.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(55547..56597)
                     /locus_tag="ACG84Z_000228"
                     /pseudo
     CDS             complement(55547..56597)
                     /locus_tag="ACG84Z_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(56623..56937)
                     /locus_tag="ACG84Z_000229"
     CDS             complement(56623..56937)
                     /locus_tag="ACG84Z_000229"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFP9161108.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(56953..57399)
                     /locus_tag="ACG84Z_000230"
     CDS             complement(56953..57399)
                     /locus_tag="ACG84Z_000230"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFP9161109.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(57400..59322)
                     /locus_tag="ACG84Z_000231"
     CDS             complement(57400..59322)
                     /locus_tag="ACG84Z_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFP9161110.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(59534..60430)
                     /locus_tag="ACG84Z_000232"
     CDS             complement(59534..60430)
                     /locus_tag="ACG84Z_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9161111.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(60423..61103)
                     /locus_tag="ACG84Z_000233"
     CDS             complement(60423..61103)
                     /locus_tag="ACG84Z_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9161112.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(61104..61886)
                     /locus_tag="ACG84Z_000234"
     CDS             complement(61104..61886)
                     /locus_tag="ACG84Z_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFP9161113.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(61879..62796)
                     /locus_tag="ACG84Z_000235"
     CDS             complement(61879..62796)
                     /locus_tag="ACG84Z_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFP9161114.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(62960..63214)
                     /locus_tag="ACG84Z_000236"
     CDS             complement(62960..63214)
                     /locus_tag="ACG84Z_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161115.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
     gene            64071..67298
                     /gene="fss3"
                     /locus_tag="ACG84Z_000237"
     CDS             64071..67298
                     /gene="fss3"
                     /locus_tag="ACG84Z_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFP9161116.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            67411..67725
                     /locus_tag="ACG84Z_000238"
     CDS             67411..67725
                     /locus_tag="ACG84Z_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFP9161117.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            67738..68112
                     /locus_tag="ACG84Z_000239"
     CDS             67738..68112
                     /locus_tag="ACG84Z_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFP9161118.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            68122..68457
                     /locus_tag="ACG84Z_000240"
     CDS             68122..68457
                     /locus_tag="ACG84Z_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFP9161119.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            68540..69880
                     /locus_tag="ACG84Z_000241"
     CDS             68540..69880
                     /locus_tag="ACG84Z_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFP9161120.1"
                     /translation="MYKGHRIRAGDQHLVYHFVIGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            69958..70632
                     /locus_tag="ACG84Z_000242"
     CDS             69958..70632
                     /locus_tag="ACG84Z_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFP9161121.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            70625..70789
                     /locus_tag="ACG84Z_000243"
     CDS             70625..70789
                     /locus_tag="ACG84Z_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161122.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            70865..72007
                     /gene="dcm"
                     /locus_tag="ACG84Z_000244"
                     /pseudo
     CDS             70865..72007
                     /gene="dcm"
                     /locus_tag="ACG84Z_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            71997..72287
                     /locus_tag="ACG84Z_000245"
     CDS             71997..72287
                     /locus_tag="ACG84Z_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161123.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            72546..73730
                     /gene="mobT"
                     /locus_tag="ACG84Z_000246"
     CDS             72546..73730
                     /gene="mobT"
                     /locus_tag="ACG84Z_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFP9161124.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            73727..73864
                     /locus_tag="ACG84Z_000247"
     CDS             73727..73864
                     /locus_tag="ACG84Z_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFP9161125.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            74610..76520
                     /gene="ltrA"
                     /locus_tag="ACG84Z_000248"
     CDS             74610..76520
                     /gene="ltrA"
                     /locus_tag="ACG84Z_000248"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFP9161126.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            76624..76848
                     /locus_tag="ACG84Z_000249"
     CDS             76624..76848
                     /locus_tag="ACG84Z_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161127.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            76861..77364
                     /locus_tag="ACG84Z_000250"
     CDS             76861..77364
                     /locus_tag="ACG84Z_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFP9161128.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            77424..77813
                     /locus_tag="ACG84Z_000251"
     CDS             77424..77813
                     /locus_tag="ACG84Z_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFP9161129.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            77800..80247
                     /locus_tag="ACG84Z_000252"
     CDS             77800..80247
                     /locus_tag="ACG84Z_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9161130.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            80252..82375
                     /locus_tag="ACG84Z_000253"
     CDS             80252..82375
                     /locus_tag="ACG84Z_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFP9161131.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            82372..83376
                     /locus_tag="ACG84Z_000254"
     CDS             82372..83376
                     /locus_tag="ACG84Z_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFP9161132.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            83395..84306
                     /locus_tag="ACG84Z_000255"
     CDS             83395..84306
                     /locus_tag="ACG84Z_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFP9161133.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            84493..84749
                     /locus_tag="ACG84Z_000256"
                     /pseudo
     CDS             84493..84749
                     /locus_tag="ACG84Z_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(84966..85181)
                     /locus_tag="ACG84Z_000257"
     CDS             complement(84966..85181)
                     /locus_tag="ACG84Z_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161134.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(85430..85648)
                     /locus_tag="ACG84Z_000258"
                     /pseudo
     CDS             complement(85430..85648)
                     /locus_tag="ACG84Z_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            complement(85943..87382)
                     /locus_tag="ACG84Z_000259"
     CDS             complement(85943..87382)
                     /locus_tag="ACG84Z_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9161135.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
BASE COUNT        26528 a        17450 c        16271 g        27514 t
ORIGIN      
        1 aaattgagaa acttttctat taaattattc tttgtagatg aacagatatt tttattttat
       61 gtacccactc gtataattaa ataactcacg atttctttat tcaataaaaa aacggcaggt
      121 caaggagagt acctactctt cagaccagcc gtttttgttt atcataattt ttattcttct
      181 actaaaggca attcttcttg tcctttttca tcttctggga cagcgacttc ttcaccaata
      241 ccataagctg ctctaactag agcagaaact tctgccatca tttcaggatg attagccata
      301 tagattttag cgttttcccg tccttgacca atccgatctt ctttataaga ataccaagca
      361 ccgcttttat caacaatgtc tttttctact gccatgtcta gaagttctcc ttcttgtgag
      421 atccctaaac catacatgac atctacttca gcgattttga aaggaggtgc tactttgttt
      481 tttacgactt tgatctttgt acggttacca acaatatctg taccttgttt caattgttct
      541 gcacgacgta cttccaaacg gatcgttgcg tagaatttca atgcgcgtcc tccaggagtg
      601 atttctggat tcccaaacat cacgcctact ttttcacgga tttggttgat gaaaatagcg
      661 attgtttttg ttttgttgat cgaaccagag agtttacgca atgcttgaga catcaaacgt
      721 gcttgtaacc cgacatgtga gtcacccatt tcgccgtcga tttctgctcg tggaactaaa
      781 gcagcaactg aatcgactac tacgatatct acagccccac ttgatactaa agcatcagcg
      841 atctctagac cttgttctcc tgtgtcaggc tgtgaaagaa gtagttcatc gatattcaca
      901 cctaattttt gtgcatattg cggatctaac gcatgctcag catcaatgaa agcggccgtt
      961 ccgccatttt tttgtacttc tgcaatagcg tgtagtgcaa ctgttgtttt acctgaactt
     1021 tcaggtccat atacttcgat gatacgtcca cgggggtaac cgccgacacc taaagcgaca
     1081 tctaacgcaa gagagccact tggaattgta gagatttgtt ggtcgatttt ttcgcccaat
     1141 ttcataatag agcctttacc atagctcttt tcaatttttt tcagtgcagc atctaaggct
     1201 gctttacgat catctgccaa tacgataatc ctccttatat ttacaaatca gagcaacatt
     1261 tcattatcct tatcatatct tttttagtga aaaaaagcaa gaaaaaaccg aacaaatatt
     1321 cgcatttatc attttcttaa aagctgtttt ctcaaaagat caaatccttg cataaccgca
     1381 ttatatctga tagcagcacg atctctggca aagtgatatt tttccgaaac cacgccgtct
     1441 ttagatgaaa tagcgatcca tactgttcct gcagattgac cttctaacgt gtccggtcca
     1501 gccactccgg tgaaagctac actgtaatct gttcttgcta tctcacgtgc ttgaatggcc
     1561 atctgctcca cacattcttt gctgactgtt ccatattctg ctaatagctc cggatcaatc
     1621 tccagaaaac cagcttttgt ttggagcgag taggtaacga atccgcctgg aaatacttca
     1681 gatacaccag caatgtcgcc taatgcggct tggaaggcgc cggctgtcaa actttccgct
     1741 gctgttacag tctgcttgtt ttctttcagt agttccacta cgacttttgc tagcgaatta
     1801 tcatcgccgt atccataaaa atattcccct actcgttctt ggattttttc ttctaatgct
     1861 aaaagagctt gattccctgc ctgaacatca tttgttttca ctgtcagtcg taatgtcact
     1921 tcatttggtt tggcatatgg tgcgatcgtt ggattgatct gtgtctcaat cagatctttt
     1981 agctcagtga ccagtcgcga ttcaccaatc ccataaaagc gcaaaacttt agaaattagt
     2041 ttttcttcag aaggaaaacg ttcctctagt aaaggacgta cttgttccac aaacattggt
     2101 ttcaactcat taggcggacc gggaagaagg atatacgcat gtgtatctgt ttgataaaaa
     2161 gtccctaaag caagccctgt acgatttggt agaggaaccc cgccttcgat aatctgggac
     2221 tgttgcagat tgtttttggt catttttcga tgggttgttt caaaatatgc caataatttt
     2281 ttgtatcctt ccgtattttg tatgagagac ttaccgaggt gagccgcagt tgcttctttt
     2341 gtcaggtcat cttctgtcgg tcctaatccg ccacataaga gtatgagttc acttcttgtt
     2401 tcagctagag caatcaactc ttctaaacgc tgctgattat ctcctacaac tgtttgataa
     2461 taaacttcga tacctagatc agctagctgt tctgacaaga aagtggcatt cgtattcacg
     2521 acttgtccta gtaaaagttc tgttccgaca gctattattt ctgctttcat tacttcccgc
     2581 tcccttatat agtatacgct gtatttttat atttttttat ttaaaaagag ggcaaggagc
     2641 tgtgacaaaa atcttgtcac agctccttgt tccaaataaa cagtgttctc ctgccaaaac
     2701 ctcggtcata agtcacaata tacataaaac atgaaaagct gttttttgaa attatccctt
     2761 gtgactcaga gttagacggc aggctcacaa cctctccact aaacgatact tacattgatc
     2821 ctttgaacac accgctgttt ttgatgaagt aatccacacc tgaatagata gtaaagatca
     2881 gacaagcata aagcatgatt tgatctactg gaataccgat caggctgaat gggatattat
     2941 tgataaacag caagataata gcaaccattt gtgtagccgt cttgactttt cccggccaag
     3001 ctgcagccat gacttctcca tgttcgacaa gtagtaaacg caagcctgtg acggctaatt
     3061 cacgacagac aatgatcgct actacccaac caggggcctt tccttggtca accaacatga
     3121 taaaagcagt cataactagc attttatctg ccaacgggtc cgcaaacttg ccaaaattag
     3181 tgacaaggcc tcgcgcacgg gcaatttttc catctaacca gtctgtgata ctagctaaag
     3241 caaaaataac tgcacctact agctgtgtga cagccagtgt ggtgtctcct acgttaaatt
     3301 gtccccaatc taaaggtaaa cctacaacca aaatgaaaat cgggatcata caaattctaa
     3361 gtacagttaa tttatttggt aaattcacac tatcgactcc tttcttccct attctacgtg
     3421 actatcagcg aagtttccac cgatattatt tacttttcca aatgaattta ttcaaaggag
     3481 tatttttatt gaaattgatc tttttgaatt aacgaagaag gaccgcgaca cagatttgtc
     3541 acgatccttc ttttttatac ctacaagtaa acagatgcgt aaactaattt atacgatcat
     3601 tctgcgtatt gaagagtaag gttcacattt tttggactct gattgttttc ccctggatta
     3661 actggtacgg attctccatt cgctttgatc gttgcattgc ttgctgcacc aatcgtgatg
     3721 gtcgcatttg ttgctgtttc cggtaacacg gtactctgtg tttcatttgc tgccagtgtc
     3781 ccttgataaa cataggcatt gtctactagc acacctaacc atacacgatt gacagcagta
     3841 aattcaaggg ttacaggctt ggtagcgtct gtgatattta ctgcgatggc actgccagaa
     3901 tcttctcctg tagctattgc cattttcttt tcttcacttg attttgttgt tgattctact
     3961 gtagaagact ctttggtctg cgtgctttgc tctgaggaag aggactcctc gactgatcct
     4021 tctactttaa gcgaagaagc tgtgtctccg attattggat cagcttgacg atcttgccaa
     4081 gtcatatagc ccacgacaac gacaatcgcc aaagcaacca atcctaataa aatgacagga
     4141 agacttgtcc aaaagcgact tggatgcgat tcttcctgat gcattgcttt tctagaagta
     4201 cttactgttt caggctgcgg acgttcaggg accgatcctg tcaatttgct tttcccatca
     4261 aaaacatcga ctaaatggtc tccatcttct cctacagctt cagcgtattg ccgaataaat
     4321 gcccgcacgt aaaatttacc aggcaattgg tcaaaatcat cattgtcgat tgcttccaaa
     4381 taacgttttt gaatttttgt aatctgctgt aattcatcta aagatatttt tttattcagg
     4441 cgtgcttgcc gtaatttttc tccgatggtt tcaaaagcca ctcgttcatc ttctccagtc
     4501 tgtttgattc tccgaagcat ctgctgttgc aacgaaagac gttatgtttg ggtgctgtga
     4561 caaaagtcat gtcacagctc cttttttccg aataaacatt gttctcctgc caactcctcg
     4621 gtcacaagtc acaatatcca ataaatataa gaagctgttt tttgaacttg ttccttgtga
     4681 ctcggagtta aacggcaggc tcacgacctc tttcttaaac ggtgttcaat cagctgttcc
     4741 tcggtattag ctcaaaaacc ggcaaaatat aaggagatat ttttccgtat gtttctctaa
     4801 tactcaggtc aaaacgctga tttcacaacc tcttccttaa acggtgttca aaagcttgca
     4861 tctgcggtaa taagtccaac caagttaaaa acattaagaa gctgttttta cttggctgtt
     4921 cttattactt gatgcagggc agctttttca caacctcttg gtacacggtg ttccagaagt
     4981 agcttcttcg gcaataagcc gaaatatcac aaaaatttga gaagcaattt tcgtaaattc
     5041 cttcttattt cttgaagctg accacttctg tcacaacctc tttgattact tcgtttgatt
     5101 ttattttaat ataagttgat taaaagagag catgatttgt tttattttct cactaatttt
     5161 tccaacacaa ctaagaatac cataaaagct gattttggag gaggttccta ctacaagtct
     5221 aaaacgaaat ttaagacttt tcctcataaa atactggttt attttggtct catgtaaaac
     5281 tcgctgaagg cctcttcact tataaatgct tccccagctg ccagtacgtc tttcatttgg
     5341 atcgaatcga tgatttcagg aagatcaaat aaagttcgat cgccaaataa actttgcgta
     5401 aattgattgg caatatattc gatcgaattt aatgattgga aatattgtcc aagcattttc
     5461 ttcttcagca aatcgagatt tgtttctgac acttccggat catcagcgaa tccaagaatg
     5521 atttctttga ctttttctgc tgctttctct ggttcgtccg tatctccgct gaagtccgca
     5581 aagtgaaatt cacgatccaa gctgaattca aaaccaaagc tgtcatcgat aattccttga
     5641 ttgtacatcg ctagatagtt tcgagaagta ttgcctaaaa tcatttggaa caacagattg
     5701 attgctgttt tatagcgtaa cagttctgtt ccttcttgcg gcaatgtgtc taatccttta
     5761 ataccaagta caaatttatc tcgtgtaatg gctgcttcca atgcactttg tttgatgatt
     5821 tcttttgtgt tttcagggaa ataacgtaca atttcttgct ttggagggaa attttttgct
     5881 tcttggtttt cccgaataag tttcatcaat ttctcaggct ccatcttacc aactacaaat
     5941 aaaaccatat tgcttggctg ataaaacgtc cgatagcacg tatacaagtc ttgagctgtg
     6001 attttgtcga tactttcaac cgtgcccgca atatcgatat gcaatgggtg tgtaggatac
     6061 aagttattta gtatgccaaa aaacatccgc cagttagggt cgtcttcata catttggatt
     6121 tcctgaccga tgattccttt ttccttgttt acagtttctt ctgtgaagta aggtgcttgt
     6181 acaaaatcga tcagagtcgt cagattcttt tctacctgat ccgtcgtaga aaacagatag
     6241 ctggttttcg taaaacttgt gaaagcattg gcggaagctc cttgtttccc aaataattga
     6301 aagacatcac catcttcttt ttcaaacaac ttatgttcta aaaaatgggc aattccatct
     6361 ggaactttca ccttttcttt ttcaccatag ggaataaatt cgttatcgat cgaaccataa
     6421 ttcgtactga acaaaccata tgtcttgtga tagtcatttt taggcaacaa atacacggtc
     6481 aaaccgtttg gcagtacttc atgataaagt gtttcattga tttgctcata ttctgtttta
     6541 ttcatttgca tttcctcctg ctaaaaagaa gattgcctgc aattcgattt gctcagctac
     6601 ttgttgtatc tctttgatcg ttacgctctc catacgtttc aaccattctt catcagataa
     6661 ttttgtttcc ggcagccagc tgtccaaaaa agaagcttcg attgccgctt gcggagagtc
     6721 tagagaaagc agatattggt ttctcagcat tgcttttgtc tgagacagtt ccaactctgt
     6781 tatttcacca tttcgcaaac tttctaattg ctcgtgaatc agatgaagta cttgatttcg
     6841 gttcttttca tcgataccgg tttggacact catgaatcct cggaacgtat ccacgctact
     6901 agaggcataa taagctagac tttctttctc tctgacattc atgaaaagtt tagagtgagg
     6961 aaaaccgcca aataaaccgt taaagaccat tagcgcaaaa cgttctggtt catcgtaata
     7021 cacatttgtc tgataagcta ggttcagctt tgcttgaacg attggctcac gtacttgtcg
     7081 ttccttcacg atattcactt gaggttgggt ataaaacaga tctggataaa ctgtttcccg
     7141 cgactcaaat ggtaattgcc caactgcttc agctgctttg tccggatcaa catcgccgac
     7201 aacaaaaatg tcgatttgat catttgccat catttcttga tagtaggacg ctagcgaact
     7261 agcagtgatc ttgtccaaat cttcgactac gcccaaccct gggatctttt gttccgggct
     7321 gttttcaaaa taaagttctt gcaaggcata ggaagcaaaa gtttgtttat cttccttcaa
     7381 actttccaaa tatagacgca gattgttctt ttccaagtca aacgtcaact gatcaaactg
     7441 atgattttta atatttggat aaaataaaac ctcttttaaa aaatctaccg cttgagaaaa
     7501 aaggtttgga tcattgacat attcaccatt cacaaaactg atccctgcgt ttagccaatg
     7561 taaatttcct ttttttctaa ctgataatcc aaagcttgcg ccataaagct ctgcaagttg
     7621 cgcacttaac tttgtctgat ccgaataatt caaactattt gtttccaaca tgctgctgag
     7681 aagtgaacgt ttcgtgatga cttcttgttg cagacgcgca gtaaaacgga taaaaatccg
     7741 gatcgttttg tattgttttg ttggtaagac atgaagattc acgccttctg ccaattgata
     7801 caccatattt atatgctcct tttcacagtt gattgcccgc ttactctttt aatgggtcaa
     7861 cctgcctttt ttacttattc ctctgcttga aatttataag ttcaggcaat tcgccgtttt
     7921 ttctaaatga tgttacactt tatagtatag catagatgtt ttttatcaaa agaaacagac
     7981 ggctaaaagc gtatattgtt tttttatttt ttatttttcg atatactaaa gacaaataaa
     8041 agaagggagg gtcattcatg atcaaagaat tcaaagagtt catcatgcgt ggagatgtct
     8101 tggatcttgc tgtcggcgtt gttattggta gtgcgtttac aagcatcgta aaccaagtgg
     8161 tgcaaggctt gatcacacca ctaataggtt ggtttgtcgc aatgatcaca ggtacttctg
     8221 atttagaagg agcactttca attcttgact ggtcgccgac aaaaggcgtc acatttgcgt
     8281 ttggtaacgt tattagtgct atcattacat ttctgatcac tggttttgtc ttattcttag
     8341 ttgtcaaagc ggcaaaccgt gcgaagaatt tacgctccaa agaagagcaa gtggaagtgg
     8401 aagaaactcc tactgcagaa gattatctta gtgacatacg cgatcttctt gccaaacaag
     8461 tggcagaaga caatacacat ccagtagagc aaacaaatct ttccgatact tctaaataat
     8521 aaagaatcta aaaaaaagaa agccgatttt cagtgtcggc tttctttttt tagattctta
     8581 acttgctact tgttcctttt tcatgtcgat atgtggaata tcatcttcca aatacacatc
     8641 tgagattgcc ttgaatccaa acgactcata aaaagcttgt aggtattctt gtgcgccgat
     8701 cacgattggt ttttctggaa aatttttctg gatcatgtta atcgtttctt gaacaatctt
     8761 tcttcctaaa ccatctttac ggttgtcctg atgaacaagg acacgtccaa aatggatact
     8821 ctccgcttct tcatatactc gcgtgtaggc aaggatcttc ccatcagtat cttgaaaaaa
     8881 cgtatgccaa gcttctccat caatgtcatc aacttcttga taaggacact gttgttccac
     8941 aacaaaaact gcgattcgtt ctttgacgat cgcgtaaaac tctgctgttg acaattcttc
     9001 aaatttcttt acctgatatt ccactaagca aacgccccct gcttttttat tcttagcata
     9061 ccgattcgca cacaaaaaag caaacgaacc ttacgaatct caggctcgtt tgctttttaa
     9121 actgcttcag ttaaaaattc gatctcaact gtccgagtaa gtacatctga atagctgtaa
     9181 gatactcgtt caaaagaatt ttcttcagga tccaaatcaa caacgaatac tgaaggatag
     9241 gtttctgtta aaacgccgcg gcgttctgtt tgacgctttc ttcctgtctg agcaaccaac
     9301 atgattgggc tgccgatacg accttctaaa tctttcttga ttgaagctaa agttgttggc
     9361 atacagttca cctctactat caactatacc acatattttt aaaattttca agtttaccat
     9421 aaaaaaaaaa gaaatgcaat aaaaataaat aagaagctca ttaagatttt tctaaattat
     9481 tcctcattat aaaatttcaa gtgttttttt attttgagtt ttactctccc gtaagcgctc
     9541 attacttgct tgtgatccat tgctaaacat tcagccatgt ctacaaaatc aacgccttgc
     9601 atataataat gaaaaatttt agcttctatt tttgaaaact ggatttcgca attttcgatt
     9661 gcttctttta ataaaagatg ctgaattgct aaaggttctt gcaatgtgat ctctgctaaa
     9721 aagtctggtc cttctgtctc tattttttgg tcgattgaga cttcatcttt ttgatcacga
     9781 cgcttcagcg cgttctgctt cctcaacaga gaatagattt gattgcttat aacgctttta
     9841 taataacttc caaagctaac acctttgctt ttttcgtaag ttctcaatgc ctgatataaa
     9901 gcgatccttg cttcttgttc ccaatcctca gaaacataat ttcttaaata ataggtgttt
     9961 ttcaaacgta gtaaaagtgg aaaatatttt tgatacaggg cagcaaatgc ttcttcgtca
    10021 ccattacgtg cagcgcgcaa taactcctca gacataaaat aattcctcca taaattcgtt
    10081 tatggaggaa tcttatcatc aatgattcat cgaactgatt agaacgatat gttatttatt
    10141 ttttctcatt aaatcgtcca atttttggga caattttttt aactgctctt cattccatgg
    10201 agaattacgt cggaaatcaa taaaatgcat atctttattt tcttgggcta ttgttttttc
    10261 cgtttttttt atcgtcttat ataattcata agcagaagtt cgtaatgctc cttgggaaaa
    10321 gatcatccac tgttctgcta aatcgcttgt cgccactgtc acttgtgtca aacggtcatt
    10381 cagctgacca gcgattctct cgatataact gtcagccgtt tcgtcttctt tcgtaaaaac
    10441 aacatccaac tggtatttct tataattttg ttggatgccc ggaactagtt gggcatcgaa
    10501 gacaacgatg acttccattc cttcatattt cgcataattt gataaacgat gtaaaagagc
    10561 ttctcttgca tccgccattt tgtcctgctt tttaagctgg acaagttccg gccacgaacc
    10621 aatcatgttg tagccgtcta caatcaacag ctgttttttc atggtctact ccccctgacg
    10681 ttgggaaaaa gcctgataca taagcaaacc agcagcaaca ctggcattta agctctggac
    10741 gtgcccggtc atcgggatcg tcagcaattc atccatttct tttttcaatc ctggactcat
    10801 tcctttgcct tcattaccaa tgactaaagc aattgatcct ttggcattcc atttttggaa
    10861 gtttgtgccg gtcatatctg tgccaaatac ccaaaatcct gtttctttga gctgttgcac
    10921 agcttgtacc aaattcgtca cgcgtgcaac agggacatgt tcgactgccc cagtggaagt
    10981 ctttgttacg ataggtgtga ttccaactgc tcggtgtttt ggtatgatca caccatcgac
    11041 gccacttgcg tctgctgtcc gtaaaatcga cccaaaattg tgtggatctt cgatgctatc
    11101 caaaatcaaa aagaaggggt cttctttttt ctcttttgtt cgttcaatca gttggtcaag
    11161 ggataaatat tcataaggtg taatcgcaag aacgactcct tgatgcacgc cgtgatcgct
    11221 caaagtttct aatttttgtt taggaaccca tttgactggc acagcttgtt cacgtgcgat
    11281 ttctttcagt tcttctactt tttctcctcg tgaatcttct tgaagaaaga gtttattccc
    11341 tcgcccttgt tgtagcgctt ctactgcggc atggtgccca aagacgaaat tatcttctaa
    11401 tgcttcttca ttttgatcag aaactgactg atttcgtcca gtttgctttt tatttgaata
    11461 tctattttgt tttttgtctt caaatccacg tttcgattga tgtttgtttg ttctttcttt
    11521 acccattttt ttcaccaact ttctgaatac accagcggat caattcttcc atccgctcgg
    11581 tttgttttgt caaatgcaga tagcccatga gcgcttcgaa ccctgttgcg acccgatacg
    11641 tcgtaacatc agcatttttt gcgctcgtat ggcttttagc atttcttcct ctgcgataat
    11701 aaagttcttc ttcttctgtc aaaagatgtt cttccagcat ttgctgaatc aaaaaggctt
    11761 gtgcattcgc agaaacataa ttcgttgccg cacgatgcag cttattgggt tttgtttctc
    11821 cttgatcaat caggtggtca cgaacataga tttcgtaaat cgcatctcca acataagcca
    11881 aggctaaacc gttcaattgt gtgtaatctc tcatgcttct cttctccatc gggttccttg
    11941 cggtgtatct tctaataaga tccctttttc tttcaacaaa tcacgaattt cgtcgcttcg
    12001 gacaaaatca cgattgcttc ttgcttgatt tcgttcttcg atcaattgtt caatctcttc
    12061 atctaataac tcttctgctg taaataaaat accgaagatc gaaagccatt gcgagaataa
    12121 agcttctcct tgtgccaaga cagcggcaga aactttcggc tggtctagat aagtgttcag
    12181 ccacttagca agctcataga ccactgtgat cccatttgct gcattaaaat catcgtccat
    12241 ttcttcgatg aatcgctgtt ctaaattttc taacaaagcg attttatccg catcatctgc
    12301 caaattctct gaggcagttt cttggcggaa tttcaaattg tcaaacgtat tcttcagtcg
    12361 ttgtaaattg gtggctgctt ctttcatcgt cgtttcactg tagcggatcg gacgacggta
    12421 ttgtgtggtc gccatgaaga aacgcaagac ttgtggatca acgtttttga tcatttcatg
    12481 tacagtgatg aaattcccta gagatttact cattttttca tcgtcttcgc caatcgttac
    12541 atagccattg tgcatccagt aattagcgaa ttttttccct gttttcgctt cactttgtgc
    12601 gatttcattt tcatgatgag gaaattctaa atcttgcccg ccaccatgga tatcgatcgt
    12661 ttctcctaaa tgttttgttg ccataacgga acattcaata tgccaaccgg gacgtccttt
    12721 gccccatggt gaatcccaag aaatctcgcc aggttttgct tgtttccata aagcgaaatc
    12781 taatgggtct tctttttgct gctgttcttc ccctgtacgc tgacttgctc cgacttccag
    12841 ttcatcgatg gattggtcac ttaatttccc ataattttca aatttacggg tacggtaata
    12901 cacatcacct gaagattcat aagcatagcc tttttcaacc aacacttgaa taaatgctaa
    12961 aatatctggc atatgatcca tgactcttgg atgcagtgta gcaggttcga cattcaacgc
    13021 tttcgtatct tcttcaaatg ctcggatgaa acgatcagca acttctggtg ctgtaatacc
    13081 taattcgttt gctgtacgga tgattttatc gtctacatcc gtgaaattcg atacgaaatc
    13141 gactttatag cctcgatatt caaaatagcg tcgaattgta tcgaaagcaa tggtgctacg
    13201 agcatttccg atatggatat aattatacac agtcggtccg cagacataca taccgacatg
    13261 tcccttttgt atagggatga attcttcttt ttttctggtc aatgtattgt agatttttat
    13321 cattctgatc tcctcacttt ttctcctttg attcgaacga cttttgctgg tactcctacc
    13381 gctgtagcgt cgtctggaac atctttcaac acaacggcac ctgcaccgat tttggcgttt
    13441 tttccgatcg ttaccggtcc taatatctgc gcattcgcag agagcatggc tccttgttta
    13501 acagttgggt gtcttttacc cgtttctttt cctgtgccgc ctaatgttac gccatggaat
    13561 aaaatcacat cgtcctcgat ttctgcggtt tcgccaatga cgattcccat tccatggtcg
    13621 atgaacacgc cagttccaat cgttgctcct ggatggatct caacaccagt taggaaacgc
    13681 cagaattgag cattgatctt cgccaataaa aagagccggt gctgatataa aaaatgagag
    13741 aaacgatgcc aaaacaaggc atgaaaacca gggtatgtca aaacgatctc agctgtcgaa
    13801 cgtgcagccg gatcgtttct ctttgctgca tcaatcgctc gggtaaacca actcatgact
    13861 ttccactcct ttcgtaagaa ttttatgtag gaaatcatct tcttataaag aaaagaagcg
    13921 ccttttaaat aagtttcctt atcaaaagac gctttccgcg tggttccact tttcttcata
    13981 atcaatgatt atctctgaca gctaacgcct gttatacgtt cttggctact ttgtttccta
    14041 taaaacagtt tttcctgttt tctgtgtttc gccaagacca ctcccagagg catttcggca
    14101 accattcatt gataccttgc accacccggt atctctcttg taatgatcag ctgcttactt
    14161 ttttctgttc atcgtgttta gttcagtact tgatttaaat gtgctaatga tttttcacga
    14221 ccaagcaatt cgatcgtttc aggcaattct ggaccatgca tttgtcctga tacagctaca
    14281 cggattggca tgaaaagatt ttttcctttt acgccagttt ctttttgaac agctttgatg
    14341 gcagctttga cagttggagc atctactact tccatttgtt ctagctgtgc tttgaatgcg
    14401 tggagaacag taggaactgt ttcaccagca agtacttctt ttgctgcttc attcaataca
    14461 ggatgttcat tgaaaaatag cgtagacaga tcaacgattt ctgcagcata gctcatttga
    14521 ggttgataca ggctaacgat cttcttcacc cattcgattg tcttttcatc tgggttttct
    14581 gctacacgtc catcagcgat tagataaggc agacacatgt cagtaaatgc atctagatcc
    14641 attgctttga tgtaatggtt gtttacccat tgcagttttt tcgcatcgaa agctgcgggt
    14701 gatttactta ggcgttttgg atcgaacatt ttgatcaatt cttggtgttc gaagatttcg
    14761 tcttcgccca caggtgacca gcccaataat gcaataaagt tgaacattgc atctggtaga
    14821 tagcctaatt cgcgatattg ttcgataaat tgcaagattg attcgtcacg tttgcttagt
    14881 tttttacctg tttcactgtt gatgatcaat gtcatatgtc cgaaggttgg tggtgtccag
    14941 ccaaatgctt catagatcat cagttgtttt ggtgtattgg caatatggtc atctccacgt
    15001 aaaacgtgag tgattttcat caaatgatca tcgaccgcaa cagcaaaatt ataagttggc
    15061 ataccatcgc gtttttggat gacaaagtcg ccaccgatat tatcggattc gaacgaaata
    15121 gcgcctttca ccatatctgt aaatgcgtat tctgtattgc gaggcacacg gaaacgtaca
    15181 acagattcta gaccttgtgc ttctttttct gcttgttctt caggtgtcaa gttcgcacat
    15241 gttcctgcgt aatgaggcat ttctcctctt gcgcgttgtg cttcccgttc tgcttctaat
    15301 tcttcttctg tgcaatagca tttgtatgct cgattgctag caagcagctg atcaatcagc
    15361 ggttgataga tttctttacg ttcagattga cggtaagggc cgtattctcc aggattttca
    15421 ggagattcat cccaattcat tcccaaccaa gcaaggtttt ccaactggct tttttcgcca
    15481 tcttcgatat tacgtttttg gtcagtatcc tcaatacgaa taataaagtc tccatcattg
    15541 tggcgggcaa acaaataatt gaataatgca gttcttgcat ttccaatatg caggtgccca
    15601 gttggacttg gtgcatagcg tacgcgtact ttcgtcattt tcttcctctt ctttcaaact
    15661 agactttgac taacagcaaa aattccgtca gttacggctt ctcaaatatc atttatttaa
    15721 agccactcag cacaaatttt accttttcta aggtaaatag taaagccaac tggttgaatt
    15781 tccttaccag ttggctgaat ttctttttta ttttgattgt ttagtctttt tctctgtctc
    15841 ttttttattg tcgattcctc gtcctgcatg tgcaggttta gcaaagatca tgcgtccagc
    15901 agctgtttga agggcacttg ttacaacgac ttcgatacgt tcattcatgt aatgctgtcc
    15961 atcttctacg acaaccatcg tgccgtcatc aaggtaggct actccttgtt ggcgttctgt
    16021 cccggctttt actactagaa cattcatcgt ttcaccaggg atgacgactg gttttacggc
    16081 atttgccaac gcattgatat taagaacagg tacattttgg aattcagaga ctttattcaa
    16141 gttatagtca ttggttacaa tgacaccatc taaaagctta gccaatttga tcaatttgct
    16201 gtctacttca ctgatatctt caaagtctcc atcgtacatt tcgacagata taccctcttc
    16261 tttttgcaag gcatttagga tatctaatcc gcgacgacca cgcacacgtt tcaaactatc
    16321 ccctgagtcc gcgatgtatt gtagttcgta aagaacaaaa ttagggatca tcaaggttcc
    16381 ttctaagaat ccagtctttg taatatcata aatccgaccg tcaatgatca cgcttgtatc
    16441 caagatttta tatttatgga aattttctcc tgattttcgt tctaacagtt gactctcaac
    16501 ttgactagct gtttcttgct cgattttttt gcttcgtgaa ccaaaaactt tcttccattc
    16561 ttcgattcgt gtcgttccca ttctcaatcc cagatagcct aagatgatca tcagtaaaat
    16621 cggcaataca ctattgacga atggaatttc catattgtaa agaggggtcg agatcacaac
    16681 acctaaagtc aatccgatga tcgcaccgat cgcaccgaag agaagataag tcaagctgac
    16741 ctcacttagt ttttgttcta cttgtttgat aatagctgag atatgtttgg ccaacagcaa
    16801 agataataaa aagaaaataa gtgcgcctaa caggctgttg gtaaatgtat tattcagcca
    16861 tccgtttgac tgttgaccga ttgcctgcca agctgagggt aaaaatgaaa tacccaagct
    16921 tgcgccgaca atgatcatca gcaaagtaat gacacgtttt tgcatcgttt ttcctccgtt
    16981 tcgacaatca tttattagtt agcggaacac acgcttcaac gtttcagcca aagttgctac
    17041 tccaactatc tcgattcctt ttggcgcttc ccagttacct aagttgtttt taggtaggta
    17101 tacttttgtg aagccgagtt tttggacttc tttgactcgt tgttcaatat gactgacacg
    17161 tctgatttct ccagtcagtc caatttcacc gatgaaacat tccgttggct gtgttccttt
    17221 ttctttatag cttgaagcaa tactgacagc gatagctaaa tcaatcgctg gttcatttaa
    17281 ttttacccca cctgcagctt ttaagtaagc atcttgattc tgaagaagca acccagctct
    17341 tttttccagc actgccatga tcagagatac ccgattgaaa tcaagacctg ttgttgttcg
    17401 tttggcattt ccgaacatag taggtgtgac taatgcttgg atctctacca aaattggacg
    17461 tgtcccttcc attgccacaa cgatagcaga gccagttgca ccgtctaggc gttcttctaa
    17521 gaaaatctgt gaaggattag cgacttcttc caatccatgc tcatgcattt caaaaatccc
    17581 aatctcattc gttgagccaa atcggttttt tactgctcgc aaaatccgaa aactatgatg
    17641 ttgttcacct tcaaaatata acaccgtatc caccatatgt tctaacattc ttgggccggc
    17701 gatcgagcct tctttggtaa catgaccgac gataaaaatg gctatcccat ttgttttagc
    17761 ggttttgagt agttctgcag tggtttctct tacttggctg acacttcctg ccacacttgt
    17821 gatgtctggc tgcgtcatcg tttggatgga atcaatgata acataatcag gggagatatg
    17881 ttcgatggca cgactgattt cgttcatatc tgtttcagcg tatagataaa attctgtgtt
    17941 gatacttccg aggcgttccg cgcgtaattt tatctgctct gcgctttctt cgccggatac
    18001 atataagact tttccgccta tggctgctaa ttgctgagaa acttgtaaca gcaaagtgga
    18061 tttcccgata cctggatcgc caccaatcaa gaccatagac cctggcacca cacctccgcc
    18121 taacacacgg ttcagttctt ctaattttgt tttgatccga ggttcttttt tagggacgac
    18181 gtctgcgatt tttgttggtt ttgctttttc tcctgtcaaa cttgtccgag ttctgcggtc
    18241 cgttgtatct tgttcgattt cttcgaccat cgtattccat tttccgcaat ttgggcagcg
    18301 tcccaagaac ttaggcgaca catacccgca attttggcaa acaaattgta cttttgattt
    18361 ttttgccatt gtaccgcctc cttttatcct aatcatgaga cattaaatca agcttaagta
    18421 tctttaacgt tttatttact ggaagaacca aatccgcctt gacgttgagc agtcgtttga
    18481 tcttgatctg cttttaaaaa cggcaaaaag atcccttggc cgatacgctc gccttttttg
    18541 atcactacat ccttgaaacc aaagttggtg aattggaaca tgatatggcc ttcatttgcc
    18601 tcattattgt aataatcact gtcaatcaca cctactccgt ttgtcaacac taaaaaccgc
    18661 ttcaacggat tgcttgaacg gttagcaagc tgcaaaaatt catcttctcc catgtaagct
    18721 ttgattccag taggcacgag ggttggtttc aattgttttt cattttctga tacatctttt
    18781 ttcaatccat ctgcgactgt ttccaacccc tttttccagc ctgctttcca gatacttgga
    18841 atcacgacct cttctgctgc ttcaaaatca tagccagcag catgatgtgt agcgcgctgc
    18901 ggtagattga tattttgatc tttatattta gaaataactt caaatcctct ttttctcacc
    18961 ggttttcctc cctaaataaa ctactcctat tctaacatat ccgaggctgt aaaagacttt
    19021 ctttacaaat tcttcaagaa attctgctat cttaaagtaa accattaatt cgttcttttt
    19081 ccaaacgact gcaagttgta caaaaaaact attttttaca tgactttact cgtcaaaaca
    19141 agtagaatag aacgaaatta atgagtggat atttgattga ggtgtcacat gcgtaaagaa
    19201 attaaaaatg caaaacgaat tattgtcaaa gtaggaacaa gtacattgat ttatcccaat
    19261 ggaaatatca atcttgcggc aatcgatcag ttagcttttg tcctttctga tcttagaaat
    19321 cggggaaagg aagtgatctt agtctcatca ggagctgtag gcgttggtat gcataaatta
    19381 catttgtcag aacgtccgac tttgattcct gaacagcaag ctgcggcggc tgttggtcaa
    19441 gccgaactga tgaatatcta taatcaaaga ttcagtgtat ataatcaaca gacggcacag
    19501 atcctcgtga caagagacgt ggtagattat cctgaaagtc gtaaaaatgt gaggaataca
    19561 ttggaacagc ttttgattat ggacacgatc cctatcgtga acgaaaacga tactgtagca
    19621 gtggatgaat tagatcatct gacaaaattt ggcgataatg atcagctgtc agccatcatg
    19681 gcaaaacttg tcgcggcaga ccttttgatc gtcctttctg atatcgacgg gttttattca
    19741 gataatccga ctacaaatcc cgaggctcag atgtatcgct atatcgataa aatcgatgaa
    19801 aagattctgg cacaagcagg tggtgctggt agcacatttg gaacaggcgg tatgcagagt
    19861 aaattaaaag ccgcttctag gatatttgaa gcaaacagcg caatgatttt agcaaatgga
    19921 aaaaatccgg caattatttt tgatattctt gcaggaaaag aagtaggtac tttatttaag
    19981 gaggacttga aatgactgac ttgatgcaat taggacaaca ggcaaaagat agcgcgcaac
    20041 aactagcact tatgcctaca aaccgcaaaa atgagctact tgttcaaatg gcacaaacca
    20101 tcaaaaagaa tcaacaagcg atcattgaag caaatcataa agacttagaa aaagcagtcg
    20161 aaaacaatat cagtgaaacg atgcaagacc gcttgcagct gacacctgag cgaatcaatg
    20221 ccatggctac agagatcgaa aaaattgctt cgttagacga tcctattgga aaagtagatg
    20281 agatgtggac gaacaccgac ggattgagaa tcggcaaaaa gcgcgtgcca ctaggcgtga
    20341 tcggcatcat ttacgaatct cgtccaaatg tcacgacaga tgcagctagt ctagcattca
    20401 aatcagggaa tgccgttatc cttcgcggtg gcaaagaagc attcttctcg aatcaattat
    20461 tagtccaatt attgcagcaa gtactggtca gtgctggcga atctccttat gccatccagt
    20521 ttgtcgatga tacttctcat gaaactgcag gacagttgat gcgattgaca gaatacttag
    20581 atgtgctgat tcctcgaggc ggagcaaaat taatccaacg agtcaaagaa caggcaacgg
    20641 tacctatcat tgaaacaggt acaggaaata atcacgtata tatcgataaa gaagcacagt
    20701 tatctatggc agtgaacatc atcgtcaatg caaaagcttc ccgtccatct gtctgtaacg
    20761 cggcagaaac attgctgatc cattctgaga tcgcaccttt tttcttgcca gctattgaaa
    20821 aagaactggt agaacacggg gtctctttac gtgcggatgc tcgtgcgtta gaatatctag
    20881 agacggctgc tttagcagaa gacacagatt gggatactga atatctagat tatatccttg
    20941 ctgtcaaagt ggtcgattct ttggatgaag caattgcaca tatcaatcgg cataatacta
    21001 aacattcaga aacgatcgtg acagatagtt atgcggctag tcaacgtttc ttaaatgaag
    21061 tggacgcggc ggctgtctat gtcaatgcct ccactcgttt tacagacgga tcggtatttg
    21121 gttttggtgc agagattggt atctctactc aaaagttgca tgcccgtggt ccaatggggt
    21181 taaatgaatt aacttccaca aaatatatca tttatggcga tggacaaatc cgcgaataat
    21241 gtttcgtgtg aaacattatt cccgcctttt gccttttttc tgtaaaggtt ctatccaact
    21301 agaaaggtgt caatatgttt gaaattttaa tgattttttt tatttacctt atttctctga
    21361 atatcgctgc ttttctggga gtcggtattt tatccctttt ctttcaattc aaaaaacgaa
    21421 gcatagggag tcaacgggaa aaatggtcgc agtattttga caaaatcggg caaaaagggc
    21481 tggttacacg cttgcacatt agttacatgg ttgcattatg cttattagcg acaatcaatt
    21541 actattcttt tttcgatcat tcaatcgctt atacgattac gctactgatt gctgggattt
    21601 ttcacttatc ttataaatat cagctgaata aaaaccactt gaatcggact ttccgctaaa
    21661 aaatatccgt acgataagta gagtgccttg aagatcggca aaaaactgcc ggacttttta
    21721 gaggctgtga caaagatttt gtcacagcct ctttttccat ataaacggcg ttcgcctacc
    21781 agctgcctgg taaatctgtt tcctcttcgt taagaagcga aaatccgtca aatgtttcgc
    21841 catcataata acgaagcagc tcatccatgg acaagttcat cgttttttct ttttcttctt
    21901 ccgctgattc agccagtagc tgttcccgat acacctgata cataccagct attttttgct
    21961 gcatcgcttt tctagtttca ccttccgcat tgattattgg caattctttg atatagccac
    22021 gataaatcaa ccgatcatct gaaaattcaa tgggtaattc aacgagtgtc aacccgactt
    22081 cctgaaaata ttcttccagc atctattatc cccccattct ttttcttaaa tgaattttag
    22141 cttacctact gaaaattttc cagtttcatt attttgagaa aaaaagggaa tgtgacaaaa
    22201 atcgtgtcac atcccctttt tccgaataaa tggtgttctt ctgccaactc ctcaatcata
    22261 agtcacaata ttcaacaaac atgagaaact gttttttgaa attgttcctt gtgattcaga
    22321 gttaaacgac agtctcacaa cctcttggta aacggcgttc aatcagctga ccctcggtat
    22381 tagctcaaaa aacggtaaaa tatgagaagc tatttttccg ttttgtttct ctaatactta
    22441 ggataaaacg ctgattttac aacctctgtt aaacggtgtt caatcagctg tccttcggta
    22501 ttagctcaaa aaacggcaaa atatgaggaa ctatttttcc gtttgtttct ctaatactca
    22561 ggacaaaacg ctgattttac aacctcctga taaacggtgt tcaaaagctt gcatctgcgg
    22621 taataagccc aaccaaacga aaaatatgag aagctatttt tgtttggctg ttcttatgac
    22681 ttgatgcagg acagcttttt cacaacctct gatttcttat tcttcttcat ttgtagcaaa
    22741 ataattacgg tgataaatga tacaacatac actgataaga acaatggcac ctgcaaaata
    22801 aaacgcatag ctttcaccaa tatgttcacc aatcacacct gcaataaatg gtgctaaagc
    22861 tccaccgaaa aagcggacaa aactatagct ggacgaagca acgtttcgtt gcagacctgg
    22921 tatttccata gcaatcgtcg tcaacagtgt attgataatt ccttggaaaa atcctgctaa
    22981 cacaatgctg atcggtacaa ggactggcat agaagttcca gctcctaata acagcaaaca
    23041 aataatgaat aagacaaatg ctgctaaaat tgtccgataa gtcgtaaact tccgctcaag
    23101 agccggtgca acgaaaatcg aagcaatagc cagaagcaca ccccagccaa aaaatacaaa
    23161 accgacttct aattcagaat agccaatcaa taaaaatggc gcatacgcaa gtaaagtaaa
    23221 gaatccgaaa ttatataaca atgcgattag tccaactgaa cgaagtttat gattgcttaa
    23281 cgctttgaca ccttcccaaa ggcctacttt tctctttggt ttctcagttt caggtaaaag
    23341 taccgctagg gctataaaac cgcaaaacat caaaaatgct accccaaaaa atggataacg
    23401 ccatgaacca ctgcccaaga ccccaccgac tagagggcca acagccattc cgcagccaag
    23461 tgctgcttca tacatcatga ttgctttttc tgtgttacca actaaaatac tgacgatcgt
    23521 tgctaaagca gtagagacaa ataaagcatt cccgacaccc cagccggcac gtaacccaat
    23581 cagcattccg atattcccag ataatccgcc aagaccagcg aatacaacga tgataaacaa
    23641 tcctgtcatc aatgtttttt tcaaaccgat ccgactagat aagaaacctg taaatagcat
    23701 caccacacca gtgactaaca tgtaactagt aaataacagg gtcgtttcag ctggcgtagc
    23761 gtttaactgt gcagcaatcg tttttaagat tgggtctact agacccactc ccataaaagc
    23821 gatcatacag gtagctgcta caactagcgc tgaacttttc ccctttgttt cttcatttgt
    23881 ttgttcttgt atatctattt gattctccaa tatttccatc cctttctctc tattagcatc
    23941 atacatgatt tattttacat gtcaatatgc acatgtaaaa cgtggaaact ttactgtgat
    24001 ataataaaga aaataagacg agaggtagga tttttatgaa tactttagcc tatatattat
    24061 tatgcgtgct tttatccaaa ccacgttctg ggtatgaatt gaagcagctg atcacaattt
    24121 tttgggaagc ccatcacagt cagatctata caacgcttgc caagttagac cagcagggtt
    24181 atgtgaccgt tttggacaaa gacgagcact ctcaaaaaaa gatctaccac ttgactgatg
    24241 aaggacgtgc tcttgtagag gaatggatca aagaggaaac tcccgctcct acgcaaaaag
    24301 atgaatttct agcaaaaatc tatgcttttt cgacgctcga taaaacaaca gctactggac
    24361 tgctattcac tagagaacaa cagctgaaca aaatcatgca aaaaaatcaa aaaaaattga
    24421 atgacctctc gctagacaag aaacaagaat ttggacgtta tgttgtgatc cagcgcagaa
    24481 ttatgctttg tcagcaggaa ctccaatggt gtcagcaagt aagagaacaa atgcagcagt
    24541 tttttgagta agggataaac agaacctttc tagaaatatc tattgaagag caaattatct
    24601 tcaataaaag agcaatacag ttggaaaaga aaaagcgatc cgaacgacag gccaaaacct
    24661 atcgttcgga tcactatttt tctagaactg cattcaagag actatgacaa aaagcatgcc
    24721 aaggcctttt ttcaaataac agtgttccat cattcattac tttgaattgc ttttagcaca
    24781 cttcttgaaa gcgggccaac gatgatcaac tgcaacggta aagcggcaat cacattcatt
    24841 ttccaagcat tcatataagc agagaataat tgatcaggta ttccttgttc catgatcaca
    24901 ccgaataaag acatacatgt caccattcct aaaaccatca agcatgaaat agttaagatc
    24961 atttggacct tgctttctgg atttactggt agtttaaagg caattttttt cgccagcaca
    25021 ccgatgatga agacatccaa aatgaaagcc accacgaatc caggcactag accaatcaac
    25081 aaacttgata aatgaagatc ttgatgcagc cataaattat acgcgctcat ccccaagacc
    25141 atcaaaaaac acatcattgt tgtaaaaatt attccttctt ttttatttgt aggcaatctg
    25201 taccactcct ttaaatttgt cacgaaaatc atcgtagcac atttaaaaat ttctcgtaag
    25261 tacttttttt attttctgcc cttttatttc ataaacttca tcagccgtac gctcgacaaa
    25321 gtaagaatca tgagaagtaa acaaaatcgt tcccggatat atttgcatta gcttctctaa
    25381 agcttcgatc gttgccatat caataaaatt agtcggttca tctaacagca acacattact
    25441 tggcttagta aaaagcaaag caatcgtcag acgggtcgct tctcccccac ttaatgtaca
    25501 taacggtttc gtcaaagttt cctgagcaaa ccctaagtga ttcagcaaac tacggacaag
    25561 cgattctgaa aactctgttt gtctcatgac aaaacgaatg atggattctt cagatgtcat
    25621 ttgataaccc ttttgctgat atacttgaaa gcttactttc ggagagagaa ggattccttc
    25681 tccttgtttg cggatatgtt ctaataaggt tgtcttacct gaaccatttt caccgacaat
    25741 cgcgattttt ttacctaaag aaaactgaaa atcaccattt accagtaatg ttctcccact
    25801 tctttccaat tggacatttt gtcccatgat gggatagcgg ctgtggagtt caagagattt
    25861 tggtactgga aaacggattt gtttcatctg ctgcggcttg gttgtttctc ctattttttg
    25921 gagtcttctc tctaatgttt tcgcattctt ttggatggct ttttgtacac tgtctttttg
    25981 tttagaggaa gacaaccgat ccagtctgat ttgttgcttt ttctttttac tggacacttt
    26041 ttccaacttt tccgcttgtt ttttcttttc ttggatcgat ttttccaatc gttttttctc
    26101 tttcatgatc gactctgctt ctcgtagctg agtctttttc tccaattcct tttgagtgag
    26161 ataggcacta taattccccg aaaactctcg gatttctccg tcttttactt cccagatttt
    26221 cgatgctagc tcatctagaa aatagcgatc atgactaaca aaaaccagcg taccataata
    26281 ataacgaagc tcttcaatca gtcgatcaat actttttcta tctagatggg ttgttggctc
    26341 gtctagaagc atcccttgtt cataagaaga aagaagacgt atcaactcga tctttcgttc
    26401 ttcccctccg ctccatttcc gctctgaagt ttcttccagt cttaactgga aatgactggc
    26461 taattccaaa tttaggtcct ttgcttcagc gagataggtt aattgaggca ggtagttgaa
    26521 ggtgatctct gtttggattt tcccatgatc gggaaaaagt tcaccggcta ttagtttgag
    26581 caaagtcgat ttaccgacac cattttctcc tatgatccct atacgatctt gctgatagac
    26641 acgaagagaa tcaatagata gttctagctg gttgccaaag ctgacttgta gatttgttat
    26701 atttactgct aaattttcca tatgttttac actcctattt catgtaaaac aacaattatc
    26761 gatactaaaa aagagcagaa aaatctgttt gcaaaaaaac tgcatcacat cttttcctac
    26821 tctgaacgaa ataactatga ctaaatcacc aaatctgtca tagctttcac ctattctact
    26881 gtcgttcgaa aaaatggaca tactccatcc atgaaattgt tgtttataca tgtcttttga
    26941 atttatttag ttgttattca aaagttcgaa acgtaatttc atcgatgcag tcatttttcc
    27001 gacctccttt tttattaggt taccacacac gattcaaaaa aagcaatagc tactgaatag
    27061 taactgaaaa ccttttattc gaacatagtg atcttttctg gtgctaaacg aacagactcg
    27121 taaccttctt ctaccgcttt tcctattgat aaaataataa ctggaacata acggtcttta
    27181 tccaaaccaa atgcctctgc caactgatct gcttcgaatc caccaattgg atttgtttca
    27241 tagccatgat cacgcgcaac taacatgaat tgcatagccg ctaagctaga atcgactttg
    27301 actacatcgt tcatttcttc tcttgaaaaa ctcttgtaat aaggaatgat cgcagctaat
    27361 tgttgatctc tgacttcttt tggcatcttc cctgattcgt aagcttggtt gtagatttct
    27421 tcgccatatt cgtaacattg catatcgcca aaaatcatga ccattgcaga agaagtatca
    27481 ttttgtctcg tattgaaacg gatcaaagga cgcaagattt cttttgcttc ctcgctttca
    27541 gcgaccacaa agcgccatgg tttcatattg acagaagaag gtgcagtcgt cgcttctttg
    27601 atcatttcca gcatttcttc gtgtgggatt ttgtatgttt catcatatac gcgaacggat
    27661 cttctaccag tcataattgt tgaaaaatca tttttttgtt ccattattat taacctcttt
    27721 cgtttctgtt gttatattgc aaagttgggt attcaattta tctaaaagtg ttagaaattg
    27781 tttcatttct acatcgctga aagccgggga tagcacggaa cctgtatctt tatggtccat
    27841 ttcacaatgc ttgattttct tctgggcttt ttctgttagc gctacataca cttcccggtt
    27901 gttctgagga tttctctgac gcgaaacata gccatttgct tccaatacct tcagatgacg
    27961 agtaactgct ccttgatcaa tctgcaactt ttcttgcaaa ctgctttgta gcaatggatt
    28021 ttcttctttc agtctcatca tgatctcgta tctagtaaga cttataccga tattttcttc
    28081 aaagatctgg acgatttttt gatcggctaa tttgatttga tataaaaggt gactaatctc
    28141 ttctaaagac ataatttcct cctttctaat aattgactcg tcaacgattg acttgtcaat
    28201 aatagaataa aaaaagaaaa aagtcaaaga atcagctgtg taataaaaaa aacgctctca
    28261 atagaaaagt atagagaaaa gaaatttttt gtagaatgaa cggaaaaaat gataaagaaa
    28321 gcacaacgct aaaaccaaga ttattgattc ttatcaaact atagaagata gctcttctgc
    28381 agtagataat tttacaccgc caaaaatttc cgaaatcgcc ttttgcaaga atcccgtcga
    28441 atattagaaa ttggatcagt atgcttaaac agtaataaaa aagttatgac aagatgttgt
    28501 cacaaccttt tttgagtaaa cggtgttcaa aaacttgcat ctgcggtaat aagttcaacc
    28561 aaacaaaaaa catgaaaatc tgtttttgtt tggctgttct tactacttga tgcagggcag
    28621 ctttttcact acctcttttt aataaccata aaatcctatt ccttcatatc tccagcccat
    28681 cggtgttagc caatctcttt ccttagcact caaggtatag tgatgggtac cagttttttc
    28741 atttggatta aatagtcgat aaattggctt ggaaccacca gaataaaaac ttagaccttc
    28801 ataacgccaa ccgatttttg ttaaagagtt gatctcagat tgtgccattg tgtaatgatg
    28861 gtctccactg taaggattgt ataaacggta gacaggttgt ccgctgtttg gtgcttgcca
    28921 agcaatccct tcatattccc agcctacagt tggcagataa tttttttctc cggcattcaa
    28981 tgtatataaa tgttctcctg tatgacggtt atacagacga tacatcggag aagttgaagt
    29041 tggtgctgta tcatactgtg tcagattata ggtttcgatt acattgttca atgtagaacc
    29101 ataattaggc gcagtggcat aacgacctgt tagccaagcc gtagcatctt tgtaagagtt
    29161 cgtattgctt ttccatgcac cggaatagta gtaaacgcct ggctgaaaag aagtcgtctt
    29221 caataccgtt acgttatctt gcaatgattc tttgtacgaa ggatattttc taaaagcggc
    29281 attcaccgta atccattgcc cattcacata ttccgaagta ggcatcgtaa cagattggcc
    29341 attatagctt cctttaatcc caaatagatt gtaattaggg gcagaagcca aagtactgtt
    29401 cccccagcca ctttcaacga tggcttgagc aatcatgact gatgcatata agtcattggc
    29461 acttgccaaa ctttgtgcag ttgaggcaat actatcaatg aacgcttgtt gagaattagc
    29521 agatgagcga gcataaaaag catagccagt atagttttcg aattcagaca aatctgcttg
    29581 atgggtatgt gtcaatgttt gcccatctgt caattggttc gtgatttctt ctgcattctc
    29641 tggattgttc tgagcttctg ctgatgtact gtcttcggtt tgtgtttgtt ctgttgtttc
    29701 agttgttggt tcttcggttg aaattgtatt ttctgagaca gtagctgact gcaaagtact
    29761 ttctgtatcg ttttcaattc ctgtttctga agaactcgat gtctgagttg cgacagtttc
    29821 tgtcgattct tcagctagca ctgttgtgtt ggcaactgct agatttccta aaagaataac
    29881 gctaaataat aaattctttg ctttcatctt ttttctcctt tgaattatga aacttttcct
    29941 aaataacagt gtaactaaaa aagtaaaagc aagtcaatgt ccatatttaa ataacatttg
    30001 tttcttttta ataaatttgc tttttctgca taaaaagacg taaatgaaga atattcttct
    30061 ccattcacgc cttaaattga tggtcgtttg aataactatt taacaagtaa ttctctctgg
    30121 atattatccg ttatggatta tacttcctgt gtcgtcggac ggataatcat gttgctgaca
    30181 gacatccggt ctggcgtttc tatcgcaaat gctacagcag aagctatatc ttcagatgtt
    30241 aatccccatt ctttttgcgc ttcatgaagt tcaagagcag cctttttgtc gctgatggtt
    30301 tgatataatt cagtttgaac agctcctgga gagatgatcg tagatttgat gttattttgc
    30361 cgttgctctt gacgtaatcc ttccatgatt gcacggacag caaattttgt tccgcaataa
    30421 acggcggaat caggataaac aacatgtccc gccacagaat cagttgaaat gatatgccca
    30481 gatttttgtt tttccatgat tggaagtacg gcggaaattc catttaacac acccatgatg
    30541 ttgatatcaa gcatattttg ccattcatca cggtgacctt caactaatgg agcggttggc
    30601 atgattcctg cattattgta caatacatcg attcgaccga acttttccat cgctaaatcg
    30661 ataactgctt ggacttgtgc aaaatctctt acatctgctg tttgaatata tagctcagct
    30721 tctggtaaag attcttttat tgcttttagg cgatcttctc ggcgtgcagc tataactagt
    30781 ttagcccctt tttctgctaa tagcttcgtt gttgcttcac cgattccgct tgaagcgccc
    30841 atgatgacaa tcactttttc tgataaatca ttcattctat tctcctcctg ttttgaaaaa
    30901 tctcttgctt atactcacta tctcttattt catcttactg ttcaaataat ccgttcgaca
    30961 ggtttgacga ttttggcagg gattcctgca acgatggtat tgtctgggac atctttcgta
    31021 acagttgcat tcgctgcaac aatggcattc tcgccaatcg ttacgcctgg cagaatagtt
    31081 gctcctgctc cgatccaagc atttttcttg atgtggattg gctttactga caagcctctt
    31141 cgttcttttg gatcggttag atggttcacc gtgatgaggt tgacacgagg accaatcaat
    31201 actgaatctt ctaaacagat gccacctaag tcaacgaaca tcacttgacg attgataaag
    31261 acatttttcc ctatactaat atgtttgccg aaatctgtat aaaaaggcag cagaacagtc
    31321 accgtatcat ctactttgtc actaatgata ttttctagcc gtttgcggat atctgctggt
    31381 tcatggtacc cagtattcag cgctgctaaa ggctcttcgt tttccgcttg gatctgatgg
    31441 atcacttcaa agagcggatc cgttactcga atctctttat tgacgatttg tttttcgatg
    31501 aggcttgtca ttttgctccc tccttttatc cttactttat aacggacggc ttatgatgtc
    31561 taatacttat aaaacatact taactattcc ttttaactat acttagtggt atgctttttt
    31621 aaaaacagga gggaaaaaat ggatattcgt atactgacgt attttttagc agtagctaga
    31681 gaaaaaaata tcagccgagc agcaaaatct ctgcatatca cgcaacctac tctctcaaaa
    31741 caactgaaag atttagaaga agaacttggt gtgacacttt tcactcgagg ctcccgagag
    31801 atacagttga cggattctgg tcgatatctt tattcaaaag gaaaagaaat cttgtcgttg
    31861 gtagaaaaaa cggcgaacaa tttaacaaat gacgcaatca tctctggaga aatctacatt
    31921 ggcggaggcg aaactaaagc aatctctttc atttctgata gccttcattc gttgatcaag
    31981 gcgcatcctg atatccagtt tcatttatat agcgggaatg cagatgatat catagacaaa
    32041 ctggatagcg gattacttga ttttggactc gtaatcgaac cgacaaacaa acaaaaatac
    32101 cagtcatttc gactgccagc ccaagatcgt tggggacttt tgatacatcg gaatcatcct
    32161 ttagcaaagc aaacagtcat ccatccgcag gaactgaaaa ctgttccttt gatcatttcc
    32221 cggcaaacgt cagtggacag tcaactagct gaatggctag gtttcagcat agatcagtta
    32281 tcgatcgtcg gaacatataa cttattgtac aatgcttctt tgatggtcga taacgggact
    32341 tttggtgcat tagctctaga tgggatcatc aatacttatg ggacggaaaa agtattcatc
    32401 ccactcgatc cgccattaca agcttcactg aatctcattt ggaaaaaaga ccagcctctt
    32461 tctcctgctg ctcgtaaatt tttagatgtc ctaacggaga aatacagtta agtagagttt
    32521 ttttccttcg ctttcagctt tttaacaacg aataagttaa gcaaaagatc caatgattaa
    32581 ataacataag tttcttaatt tgttccttcc ttttatttct gataattcca gtaaattact
    32641 ataattataa aaaaagaatt gacaaaacat aactgtctat ataaaattga ttacgttaac
    32701 aataattcgt ttcatgtgac tagatcatac taggcatgaa aaatctctga ggaacatggt
    32761 ttccctagga ggtttttcgt gtctattttt gtttggccgc aatcaactgg tctagcaaac
    32821 gtgaaaacca aatcttcaaa aagggtgcgc gcatgaaaat caaaaagatc tttaatcaaa
    32881 atgcagtatt ggtagatgac ggtggacagg aaaaagtagc tattggaaaa gggattggat
    32941 ttgacagaaa aagaaatgat ttgatttttg atcgtgatgt cgaacggata tttgtcatgg
    33001 aaccagaagg tcaaatcaag ttgcaaaatt tacttaatca gattgatgaa cgctttttat
    33061 ttgcagcaga aacgatcatt gatcatgcgg aaactgtttt gatggaaaag ttgaatgaac
    33121 atgtattgat cgctttgacc gaccacattg ctttttctgc ggagaacatt aataacggta
    33181 tcgtcatccg caacaaactt ttaagagaaa tcgaagtgct ttacagtgat gaattcagta
    33241 ttgctcaatg ggcagtagag tatctgacaa aagagcttgg gattccatat acttatgacg
    33301 aagcaggata tatcgcaatc catattcaca gcggacgaag cggtcggaac aataaccatc
    33361 gcagtatccg tgaagtgacg attgtatctg acatcatcca tttagtggaa tcagaattgg
    33421 aaacagatat ccattcagaa ccattttcac tgaattattc aagactggtg aatcatttac
    33481 gactgcttct acaacgaacc catgcgcaac aatatgctgt tttagacacg gaaatcgtag
    33541 aaatggtcaa acgaaaatac ccagaaagct ataagatttc taaaaaaatc cgtgtgttgc
    33601 tgaccaaaga ataccagctc gcgatcacga aagaagaact gggttacttg gccatccata
    33661 tcgagcgttt aagaagcgca atcgtacaaa caaatgttaa caatcatgag gaggaaaaaa
    33721 attgaaagca tatctacaac gaatgggacg ttcccttcaa cttccagttg cggtcttacc
    33781 tgctgctgct ttactagtag ggatcggaaa ctggtgggca tcttatagta acgacattgt
    33841 cgctcatttt ttacaagctg gcggtaacgc agttttaggt caattacctt tgctgtttgc
    33901 cgttgggtta gcactaggga tgtcagtgga caaatcaggt gctgctgcct tggcaggttt
    33961 ggtcgcattt gaagttccag taaatgtttt aaaaactgat tcagtagcta ctttattgaa
    34021 tatcaaacca gaatcagttg atccatcttt tgctcagatc agtaacgtat ttattggtat
    34081 tattgccgga ttgattgcgg cagctcttta taatcgtttc cacgaagcaa aattaccgat
    34141 ggctttatct ttctttagcg gcaagcgtct agtgccaatc ttggctgcct ttgtcatgtt
    34201 gctgatcagt gcagtgctac tgctcgtatg gcctccggtt tactctgctt tagtttcttt
    34261 tgctaaattc attttgagtt taggctgggg tggtgcaggt ctttatggct tcttcaaccg
    34321 tttactgatc cctacaggat tgcatcaagc aatgaactcc gtgttctggt ttgacgtagc
    34381 aggaatcaat gatattggta aatttttggc ttctgaagga acaaaaggcg taacaggaat
    34441 gtatcaagct ggatttttcc caatcatgat gttcgggctt ccagcaggag catatgctat
    34501 ttacagaaat gcacgtccag aaaacaaagc aaaaacagct tccttgatgt tagcagcagc
    34561 ttttgcttca ttctttactg gtgtaacaga accacttgaa ttctcattta tgttcgttgc
    34621 ttggccatta tatgtcttgc atgcaatttt cactgggatt tctttagcag tgagtgcatt
    34681 cttccattgg acagcaggat ttgcctttag tgccggattt gtcgattact tcctatcttt
    34741 gaaaaatccg attgcgaatc agccattgat gttgatcgtc caaggattag taacagcagt
    34801 gatttactac tttggcttta actttgctat caaaaaattc catctgatga ctcctggccg
    34861 cgaggaagca gatctttcag atgacgatac tgcaacgact aattcagaca ataaatatgc
    34921 ggcacaagca agcaaaatct acgctgcatt aggcggagcc gacaatgtaa cttcgatcga
    34981 taactgtact acacgccttc gtttgcaagt caaagataca ggcctgatcg atcaaaataa
    35041 aatcaaagcc actggcgtac ctggtatgaa gatcatcgac ggaaaaaatg cgcaagtcat
    35101 cgtaggtaca gaagtacaat tcgttgcaga tgagatggca aaactacatg gtggtgctgc
    35161 aacacgacct gcacaaacaa acaccgtggt taaaacagaa acatttgccg gtggaacgat
    35221 cgaacaagat atttacgcta tcgcaaatgg gaaactgatt ccaatcactg aagtttcaga
    35281 tgatgtattc gcggaaaaaa tgatgggtga cggctatgct gtattaccag aaaatggaga
    35341 aatcttctct ccaatcgctg gtacgatcac aaacattttc ccaacgaaac atgctgtcgg
    35401 aatccaaaca gatgctggta tcgaagtctt gcttcatatg ggcatcaaca ctgttgactt
    35461 aaaaggcgaa ccattcactt tatatgtaaa agaaggtcaa aaagtcgcaa gaggtcaatt
    35521 gattgcttta gttgatcttg ccgctattca atctgcaggc aaaaacacgg atatggtcgt
    35581 tgtattcaca aatggcgaca aagtccaaag cttagaaatc gaacccgcac gtgatgtaaa
    35641 agcaaatgat aaaatcggct ctgtttccaa caaagcctga gccatcgtct tccccagact
    35701 tttttatcga taaacaaaca ggagctgaga caaaaatctt gtctcagctc ctttttccga
    35761 ataaaaacgg cgttctcctg ccaactccgc ggtaataagt ccagccaaac gtaacatatg
    35821 aagagctatt ttttatttga ctcttcttat tacttgatgc agaacagctt ttttacaacc
    35881 tctgataaac ggtgttcaaa aaccagttta tcggtatgaa gtcaaattta tgcaaaaatg
    35941 tggaaagcca ttttcacaaa atttttcttc atactcaaaa ctaatcggct ttttcacaac
    36001 ctctttatac attattcctg atccaatatt tcttttaatg ctgcttcaag agaagttaat
    36061 ggttttccca atactttttc taaatcatca gaggaaatag ctaactgatc ctttttaata
    36121 tcatgttgga tcgctaaaaa catgtcagct gcttcttgag ggaatccggc ttcttttaga
    36181 ttttcgacaa acgctgcatc acttgcttca ataatttcta actttttacc tgtcgcacgc
    36241 tctaatgcct tggctaattc ttcatagtca gttagattgc cggataattc taagatttct
    36301 ggagagtcac tttctactag tacttttgct gcagcttctg catattcacg tttcaatgcc
    36361 caacctgttt ttccatttcc tgcagcataa acgaattgac cagtttttaa agcctgccca
    36421 atgataggta attcattctc tacataccaa ttattccgta aaaatgtatg ggaaatacct
    36481 gaatccttaa tcattttttc agtgaattgg tgatctggcg ctaatacact gatcgagtga
    36541 tcggcatctg caaaacttgt ataagcgata taagataccc cagctgcttg tgctgccttc
    36601 actacattct tatgttcggc ttgacgattt cctggaacgc cagagacaaa aagcaatcga
    36661 tctattcctt tcaacgcttc tttcattgag tctaaatcat cataatcacc aatacgtata
    36721 ttaaatccag cttctttcag tgcttctcct ttttcttcac tacgtactag tacatagatt
    36781 tcattttgtg gaaccatctt ttttaagaat tccagcgcat aaccaccaaa acctccagtt
    36841 gctcctgtta ctaaataatg catatttgcc actccctatt ctttttattt gttaagattt
    36901 acagctgtac atttataaat tacaccttta tcataaagag tgtggtaaga taagtcaagc
    36961 aaaaaaaatg aaaggatgac aactgatgaa gtattctctg caatttagtg atgcaatcca
    37021 tgtacttgcc tatattgaaa tgtttcaaga tacccgatca ctttctagtg agatgattgc
    37081 cagtagtatc gaaacaaatg cagcaaatgt acgtaaaatc atgagtcagc tcaaaaaatc
    37141 cggtttgatc tttacaaaaa ccggaaaacc gcagccttcc cttgccaaaa gtccagatca
    37201 gatttcttta ctagatgtct atcgcagcat cgaaggtaat acacagctta tccaagtcga
    37261 tccaaaaaca aatccaaatt gcgtcgttgg tgcgaatatc caagaagctt tagaagaaag
    37321 ctacgctcgg ctgcagaaaa aggcagaaga agaaatggct aagatcacac ttgatagtct
    37381 gatacataaa atagccgttt tggaaaaaga aaaaagacca gaaaacacag gcctcgtaga
    37441 gagattttta taattctctc tactgtgcct gcatttttct gatcggaatc gtctacataa
    37501 attcttttat tctccggggg acaaaagcct tgtcatgccc ctttttcctc tctaatgctc
    37561 aggtcaaagc gctgaagtca tgacgtcttg ataaacggtg ttcaagtagc tgaccctcgg
    37621 cattagttct gaaaaatgca aaatatggaa agctatttcc catttttcct ctctaatgct
    37681 caggtcaaag cgctactttc acgacctcta tattatcatg gtttattgac taccggtatc
    37741 cagatttctc ccatatattt cccgttggta actcccattt cgactacagc atttggaccc
    37801 ccaacatagg cgtaatcttc tacttctctt aaaacatgcc caaaggccgt attcgtcaaa
    37861 tcatttctta attcttcagg cgattctgct aaagcgatta caacaagata cgttcctttt
    37921 gggaatggga tgattcgggt agtgtttgga acatcctgac tcgtttgaac accgacatag
    37981 tacatcattt tcccgttata gggttcgttg actgtaaaga aataatgatt ttcagcagct
    38041 tgtttcaatg catctattgt tccattaccg ataacttttt gctcaaatgc ttgtttctct
    38101 gcagccaaac cgacaaaatc cgtattgcta ctcttcaatt ccacaccaat acccgtcacc
    38161 gtaaaatctg gtttttcttc gatcctatac tttgccattt ctcccaccct ttctattata
    38221 ttaagttcat cttacataaa attaaaggga aatgacacga ttacgctctt ttttctaggg
    38281 atatttttat tttttaacta tttttttgct ttcactgcaa tccaaatctc actgtaaaca
    38341 ttactgaaat cctctcccca ttttgtaaaa gagatctcgg gagcttcgac taactcataa
    38401 tctgaagaag gaagccattc tgcatagatt ttcccccaag tatcttgtaa agtttgggga
    38461 aatggccctt tattaggaaa aatggcccaa gtgtgttctt ctatagcaag catttctaaa
    38521 tcagcgtacg gattttcttt tgtcgtagca aagccaatca tgtgcatcaa actgcccttt
    38581 tcttccaagc gggctccatc aaatccataa gaaacgttga ttacttgatt tggatataaa
    38641 tctcctaact tatgcatctc ttccctttga gtctccgtga tcgtctgcgc taacttttgt
    38701 atttcttgat tgactccttc aaatttgaca ggaacttttt tcgccacacc tgccacataa
    38761 aactgttctt tcttttcgat acgaaattcc atcgattttc ctcctctgac atcaataaaa
    38821 aatgtcaagc gtggaaaaga tttttgtatg ccgtatctgc tgatttctga aggcagatat
    38881 cctgaccaat cacgaaaagc tcttgaaaaa ccttcgactg tttcatatcc atatctaaac
    38941 gccgtttctg tcactcttga tccatctagg agatcgcgat tagccaaagc caatctacgg
    39001 tttttgatat agtccattag cgacatccct gcaataaacg taaagatgcg ttttaattga
    39061 tattcagaga ttcctgtatt ttcggctatt attttatagg aaagtccttc tgtcaaatgt
    39121 tcttcgatgt aatcgatcaa ttggttcaga tctttaagca tatttatctt cctccttgct
    39181 tgccttttta tcatattatc aaagaaagtc aattacttga tgaatcagga accaatttag
    39241 tcagatgtag aaaatgttgt atggatctaa agaaaattct caagcagcgt ttcgtaacgg
    39301 ataattggta ttatctgcct atctatgttt tacctttaga aaaataaatt ttggggaaga
    39361 cacattctaa gtaaacaaag cggtaaaaat atcttttatt cccttagtta atccgcttac
    39421 tacctactgt acaaagcaaa ttgttgttca aactgctgat cagaacgctg cttggatttt
    39481 tctttgcgat acatcatacc tcttttatca attggaacaa ttatttattt ctaacaaaat
    39541 cacttcattt ttgtcagata aataaaaaac aaaaaaagtt ccatctttaa aacacgctat
    39601 tcttttactt tttctcacat tctctaagaa aagaaaagga gaatgaattt ttgacaattc
    39661 gagcaaaagt gattatcaaa tatgtaaaat cagctacttt tttcttaaac gtttctttat
    39721 actaaatata aataagtgtt tcatgaaagg agaactagat gaataattgg cttgagtatt
    39781 ttcctgaaaa cgttttggaa cgcggttaca gctatcatct gcacggtttt gtccgtcatt
    39841 tgaactatac aagcaagtac ttgtccgcaa cagtttctgg cacggaagat tataaggtag
    39901 tgatcacttg ggatgaaaag accaacatga cttgtgattg tctatatgcc atagaaggaa
    39961 aaaaatgcaa acacatggct gctgtcttat tcgcttacga agaacgtcca ataaaaaaat
    40021 ccaactactc actttccgaa ctctcgtccc ttgtttcctc cgctagttcc tctcttgtac
    40081 gggagctttt aacagagatt cttatagaac atccgcaatt tatcgaacgc ttcaaagtta
    40141 agatgccatt tcatgcaata aattattcag ataaattaac aactatcatc cataaatacg
    40201 atcatattat caagaaaaac aaaaacagga aaacagcgaa gttcatcatg gagatgcgaa
    40261 agttcatcca agaagcagtt gaatcgctca ttcagcaaaa tgcctatctt cccgcattcg
    40321 aattgatcaa tgaagtgatt gctactctcg aaacattcta ttgggagcct gaggatgaac
    40381 gaacccttct tctgatagag gactgttatt atttatggaa agaattatta gcagaagcac
    40441 ctcatgcaga aaaaaggcaa atgttctctt ggttcgtctg ccaagtcgat catactgacg
    40501 cctcttattc aaaacgctac tccataaaaa tcctgaaaga agactttcgg gaaaaagaat
    40561 tttctaacca aaagaaaaaa atagataaaa aaactaaaga aacggtaaag aaagacgatt
    40621 tcaatgaaaa atagcaagta aacgataaca accatcctaa atccacaaga aatacagcag
    40681 accttgcttt aaaaacacga atcatgcaaa ggatgaagta aagaagactt aacgcgtacc
    40741 caatattagt catttgacta ttaggtacgc gttttgtttt ataagtcatg acaaatttcc
    40801 ttcgttgctg ggtagatttt ccggcattgt tgatagattt tatgatactt ttctacattt
    40861 tgtaagagag gttccactgc atctgtatat tggataaaat tctgacaaca actttcaggt
    40921 gtgtcgaacc actctaatct ttaaagataa atattaaaat aacgattaat aatattaaca
    40981 gtctttattt ttcaccacca aaaacctatc tttgcatata ctaaatagac gtatatacac
    41041 agataggttt gtcttgtgaa aaataatgat tatccttacc aaaaaatgtt tgtttttcta
    41101 catgttcgta cttatcaaaa aatatgatcc ttattgaaat tactggctat ttatattcca
    41161 acgacttctt gtgttaattt ttgttatctc atagtaaatt atgtttcatt ttcacttaat
    41221 ttagttgtca cgtgttcgtc aattcgtaaa aacggtaaat atataaacac acttgcggct
    41281 ataattaata tttgtaaaac agctgctcgc cagtctccgg ctgttgctaa aaatcccgat
    41341 ataactggtg gcgtagtcca aggaatttgc actactacat gattaattaa tcccacagca
    41401 gttgcaaaat atgctactgt caaagaaaaa atcggtgcaa gcacaaaggg aataatcaga
    41461 ctgatattaa atacaatagg caatccaaaa ataataggtt cgcttatatt gaatatagcg
    41521 ggagttaccg ataatttagc aaagtcctta taatcttttc tacgactgaa gataaatatt
    41581 gcaatcaata aagcaatcgt atttcccgat ccacccatta ccgcaaaggt atctttaaag
    41641 gccatattga taatatgtgg aatttgctct ttgtttgcat aagctgccat attttcttgc
    41701 atattctgaa tcaaaaacgg atctaacaat gaacctgata ttactgcttg atggatacca
    41761 aatccaaaaa atagattagc aatagatgta attaacaaaa atcctggtaa accagttgta
    41821 attttactta atggctctgt aactatcgtg gtaattagct tatttatatc catattaaac
    41881 aattgaatga ttataaatga caataaagca aacgaggtaa tcgtaataat gattgggatt
    41941 aatacattaa aagactttaa aacagcggga ggaatatttc cggatagctg aatctgtagt
    42001 ttcttattat tagaaagttt aataaataat tctgtagccg ctaatccaac aaatatacct
    42061 acaaacattc ctgaagctcc tgtataggat ataggtatca cacccgtcac ttcaacagct
    42121 ttatccgcat tttcaggagt aaacatcatc tgcataggtg ttaatacaac aaatgtcgaa
    42181 atagcaacta ataccgctgc aatatgattt gtataatttc tgcttgcaca catatgataa
    42241 gatactgctg ctacaactaa taatgtagtt atgcttaatg taccattggc aattgaagta
    42301 ccaatttgtt gtaacgtggt caatgtacta gtatcgacaa tttcccccat gaatcctgtt
    42361 ggttctaaga tcactgaatt aataagtgtc acaaatcctg ctaacatcat aaatggcata
    42421 aatgtagcaa acgcatctcg caaagttctt aaatggatct gattccccaa cttagtcgca
    42481 actataccaa atttttcaaa tacaatgtcc ttcctgctac ttttgcccat attttttctc
    42541 ctttatgctt attgtaatcg attacttttt ccacccaaat aatacatcac ttatcaaaaa
    42601 aagtaaatac ttttaattaa atatatatat cttttttagt ataaaaaaat aagctctgaa
    42661 aaaataattt tcccgagctt atttttcaac aaaaacagct tcaaaaacaa agtcttgata
    42721 taaatgtctc gataccgaat actcgaaagg tttaccagac gatagagcaa caactttgtc
    42781 tatctcaatc ataaattcac ctggatctat ttttaatatt tttgcgtcaa attcattcgc
    42841 agtatctcct ttgatacgta tgtgcgaagt ctttatttcc agacccagtt catttgtgat
    42901 ataagcatat acagatttct ttaaatgttt tggttccaag cctggtatga ctgctaatgg
    42961 catgaatgtt tgctcaatcg agtatggttg acaatcaata aaacggcttc gtacaatatt
    43021 atatacatag tcttttacac tgatacttaa tttatcagct acttttttcg atggaagttc
    43081 aattgagaaa gtatggattt ctgaatctac gtgttcttca ccaaccacgc taaacaaacc
    43141 ttcgtttgga ccaagaactc gtgagttatc aattggtgtt ctgacgactt cagtcccata
    43201 cccacttcta cttcgcaaaa ctccttcgga aacaagtaag tctacgcctt tctttactgt
    43261 taacttgctt gtatgataaa taactgccaa ttcatctcct gtaggaagtt tctcaccaat
    43321 tttatactct ccatttacaa tttttttctt tatatctaag taaatttcca tatacttcgc
    43381 aatttttttc aatggtgacc ctccaatcaa aaacatatct tcatctatac tttaacataa
    43441 ataaaccgat aaaatccaca tcaaaattat acacacaata aaaaagatat atatatttaa
    43501 acaaaactat ttactttaag ttgtaagcgg tgttatcatt aagtggaaac aggaggtaaa
    43561 aaaattatga caactatgaa aaagctaact tttccagatg atttttggtg gggttccgct
    43621 tggtcagctg agcaagcaga aggaaaagga gaaacaggaa aagcagagac tatctgggat
    43681 cgctggttta aagaacaacc ttaccggttt tatcaacgaa tcgattcctc tattacaacc
    43741 gatcacatcc atcaatataa agaagatata gaactaatga aaaaaactgg gcataactcc
    43801 tttcgcgttt ctatttcttg ggcacgaatg tttccaaatg gcggtaccgg aaaagtaaat
    43861 cccaaagcca tttctttcta tcgaaaatta ttttccgaaa tgaataataa cggaatcaaa
    43921 gtatttgcca acttatatca ttttgacatg cctgctactc ttcaagataa aggaggatgg
    43981 gaatcacgtg aagtagttga tgcttatgtt cattacgctg aaacttgttt taaagaattt
    44041 ggtgacttag tttgtcattg gtttaccttc aatgaaccac ttgggcctat tttaggtact
    44101 tatcttgaag attttcatta tccaaacctc attgacttta aacgcggagc gcaagcagca
    44161 ttcttcacta tacttgcaca cgcaaaagca atacaagtat ttaaagaact agctcttcct
    44221 agtaaaatag gcgttattct aaatttgagt cctacttttc ctcgtagtca aaatcctgct
    44281 gatgtgaaag cagcagaaat cgctgattta ttttatacgc ggagcttttt agatcctatg
    44341 gttaaaggga atttttctaa aaagcttatc ctgttattac aagaatataa tcagcttcct
    44401 gaagattata cgaaagaaga tcttgtatgt atctacgaaa ataccgctca aattcttgga
    44461 ctaaactatt acgagccacg tcgcgtcaaa tctcgttctt ctatggtgga tacatctagt
    44521 ccatttttac cagagtggtt tttcgaacca catatcatgc ctggacgacg aatgaacgaa
    44581 taccggggat gggaaattta cgaaaaagga atttatgatt tgtgcatgga tatcaagaac
    44641 cattatggaa acatcgaagc atttatctcg gagaacggaa tgggcgttgc ggatgaagaa
    44701 cgtttcatgg atgatacagg gcaaataatt gatgattatc ggattgagta tatcaaagat
    44761 catcttgctt acttatggaa ggcaataaat gaaggatgta acattaaggg gtatcatctt
    44821 tggacattta ttgattgctg gtcatggatc aacgcctata aaaaccgata tgggctggtt
    44881 tcactcgacc ttactactca aaaaagaaca attaaaaaaa gtggcgaatt ttacaagcaa
    44941 ttaagtgata caaatggatt tagatacgat gtagacttgt tagttgaata atattctaaa
    45001 attccacttg aagtgaacac attagaaaac aagaataatg agaaatacca ataacaaata
    45061 ctttttcttc atacttcatt tatacttgtc agtataagag actgtgacaa atgtagtgat
    45121 cctcagaagt taggtctgga aatctaactt gagaagattt ttttaaacta cgtccagtct
    45181 tttttatttg tttaaaattg aagttgacaa gtcttcatta aaaatttaga atattcacaa
    45241 gtttgacgac aattatgaaa atttatgtcg tgctaaagga gttttgttat tggatgaaaa
    45301 gttagatata aaaactgcga tcaaagacac gttacctacc gtttttggtt atatcggtat
    45361 tggacttgca tttggtatcg ttgggaaagc tgccgggttt catccgctgg tcgtcacgtt
    45421 gatgtccctg ctgatctatg ctggttctgc ccaatttatc acggtcagca tgcttgctag
    45481 ccatagtcca ctgctctcca tcgttctctc gacctttcta gtcaattccc gaatgattct
    45541 gatgagtatg acgattgctc cttatttcaa gaaaaatcgg ctgcttcaaa atctgctgat
    45601 tggcacattg ctgacagatg aaagtttcgc actgggaatg aataaattga actatactgg
    45661 acaaaagtta aactttcgtt ggatgaatac agctaattgg atttcttatt tgacgtgggt
    45721 gggttcttct cttgttggcg cacttttagg gaattttatt actgatccga aaaagtttgg
    45781 tttggatttc gccatcgtcg ctatgtttat cgggttactt tatcttcaag tcatttctga
    45841 tagaaacacc tctaaacgat tacagttgat cctgattggt ctcactttga ttctggtata
    45901 tgtcggactg atttttatcc caagtaactt agtgatttta gttgtaacac tgattgggtg
    45961 cggattgggg gtgtggatca aacatgcctt cttttgagtt tacattgctg actattttag
    46021 gttgtacttt agcaacttgg ctttctagga tcctaccatt tgtcttactg aaaaaattcg
    46081 atttgccgca accgttgctt gagtatttaa gttttgtccc gatcgtcatt atgtctgctt
    46141 tatggttcag cagtctattt acccaaaata tcggacatct gccgcagatc aatctcgaaa
    46201 atgctttggc ttcagttcct acacttttag ctgctattct ttcaaaaagc ttattggtga
    46261 tcgtcttggt aggaattctt tccctttcgt tgattcgctt attataaata aaaaaacaag
    46321 agcttatggc aaattactgt catgcgctct tgtttttatc aaagtcaaat aagaaaaaaa
    46381 tcggcgtatt cttgcttatc cgttgaacgg accactaaca acgacttttc ctaatatatg
    46441 tcctgtttct acgtctttgg ttgcttgttt caagttcttc gcattcatcc catctgaata
    46501 gaccttgctc aatgtactgc ggataatccc ttcatttgct aaagcagcaa tgtgcgctaa
    46561 agcttctcct tgcgtttcga tttcatagtt atagtctgtt ttagcgaaca tatactccca
    46621 gtcgaagctg atagattggt ttttccaaac acctatatct aacggctctt tgatccctac
    46681 gatcgttccc acatgtccaa atggtcggac aaggtgtttg atttgatcaa agtagcgggt
    46741 aatatcgaat aatacagcga catactctac ttgatcgatt cctaattcac gaaaactttt
    46801 acttaagtcg tgatgataat cgattggata gtctacacct gtttttttca gccattcaaa
    46861 attcttcgga cttgcagtcg cgtagacttc taggccagcc caatgcgcta gttgattcaa
    46921 aatcgaaccg acgcccccag ctccgttgat cactaagatt tttttcccgc ggttggcatt
    46981 ttcttctgga gtcagaccaa atttttcaaa taacaattca taagcggtca atgaggtcaa
    47041 cggcaaggct gcggcttctt catctgaaag attttttggt gcaagagcga caatacgttc
    47101 gtcaaccagt tggtattctt gattgcttcc tgctcttgtc gttgtacctg cgtaaaaaac
    47161 gcgatcgccg acagaaaatt tttgcacttc atcacctaca gcaacaactt tcccgactcc
    47221 atcaaaccct aagatacgta aagcatttct tatcccgtta tcttggcgaa gtttcgtatc
    47281 gacaggatta acagatactg cgttgacttt taccagaaga tcccgtgaac tgggtacagg
    47341 tatctgttct ttttcatcaa taaagctttt tggatcatcg atcgacaacc cttcataaaa
    47401 accgactacc ttcattaatt ccttttctga catacgaatt cctccttagc ttcatcaagt
    47461 tggagcatcc atacagtttt catttcaata tatatagtat gctatttgtt ccacttttat
    47521 tcatcataat tattctctta cttaaagtaa actatttgca cttttttggt taaaaaagag
    47581 gttgcgacaa gacttttgtc acaacctctt ttaaacggtg ttcaatcaac tgaccctcgg
    47641 tattcgctca aaaaacgaca aaatatgagg agctattttt gtttggctgt tcttattact
    47701 tgatgcagga cagctttttc acgacctcta attcacggtg ttcaagcaag aaatcattgt
    47761 tcactgaaaa gcgttggatg ttctttttca aaggtgtcta agatctctcg tacttcatca
    47821 gtagatttcg tattcatcaa ctgaactcgc aagtcatttg ctcctggaaa tcctttgata
    47881 tagattttaa agaaacgatg tagtcctgtg atggaacgcg ggatgatttc tgaataatga
    47941 tcttgcagat ctagttgcag acgaagtagt ccgatcagtt ctttttctgt atgttccctc
    48001 ggttcttttt caaatgcata aggattcttg aaaatccccc ggccaatcat gatgccatct
    48061 acgccatatt tttcggccaa ttcttctcct gtctggcgat ctgggatatc tccgttgatc
    48121 gtgatcagtg tttgcggagc gatttggtca cgtaaagcaa tgattttagg gatgacttcc
    48181 caatgtgcat ctactttact catctcttta cgcgtacgca aatggacaga aagattggct
    48241 atatcttgat gaagtaggtg actgatccat tcttccatct cagacatttc cgtatagccg
    48301 atacgcgtct tgacgctgac aggcaaaccg ccagctttag ccgcttcaat caattgtgcc
    48361 gctacttctg ggcgaaggat caagccactg ccttttccac gttctgctac attagggact
    48421 gggcagccca tgttgatatc gattccttgg aagcccattt ctgccatagc aatgctcatt
    48481 tctctaaaaa attctggctt gtctccccaa atatgggcaa ccatcggctg ttcatcttct
    48541 gtaaaggtca atcttcctcg tacactgtct tttccatctg gatgacagaa actgtctgag
    48601 tttgtaaact cagtaaagaa gacatccggt gctgctgcat gctttacgac atggcgaaat
    48661 acaacatctg ttacatcttc cattggtgct aaaacaaaaa aaggctttgg cagctctttc
    48721 caaaaattag tagtcattta tttgttactc tccattctat caagcagtga agtcgcaatc
    48781 tttctcaaaa acattgtcat tatactagga aacaaaaaaa gaagcaaagt gaacagctta
    48841 aaagatgttt ctgattgagc aaaaaaagac tgtgacaaaa atcttatcac aattcctttt
    48901 ccggaataaa tggtgttcaa aagcttgcat ctgcggtaat aagtccaacc aaacgaaaaa
    48961 taggaggagc tatttttgtt tggctgttct tattacttga tgcagaacag ctttttcaca
    49021 acctctccac taaacggtgt tcaatcagct gaccctcggt attagctcaa caaacgacaa
    49081 aatatgagga actattttcc cgtttgtttc tctaatactc aggtcaaaac gctgatttca
    49141 caacctcttt tctaacttct caatcctctt cctttattga tcaaatacca agtaacggcg
    49201 tacaaaacaa cgatgaatag cacaagtacg atcatcgatg ttgctactgg cacatcgatt
    49261 gttccaagga atccgtaacg gaaaccgaag atcatataaa cgatcggatt gactttcgaa
    49321 acagcttgcc aaaatggcgg caacatagag atggcataga aaacgccacc tagataagtt
    49381 aacggctgca agacaaatgt aggcacgatc gatacatcgt cataagactg agcaaaaatc
    49441 ccgttgagca gtcctgctaa cgaaaacaag attgccgtca tcaataatgt aatgatgacc
    49501 atgaaccatg aatacacatg aagtggtaca aagaacaagg aaatgatcgt tacgagagag
    49561 ccgacgagaa tactgcgacc cactccgcca atcacaaagc cccaaatgat cacatgcgta
    49621 ggaacaggcg ctaccaagat ttcttcgatg tttttctgga atttttgaga gaagaaggac
    49681 gaagaaacgt tggcatacga actagtgata gcagacatca taatcaaacc aggcacgatg
    49741 aattccatat atgaaaaacc acccatgtca ccgatccgac caccgatcat ttttccgaaa
    49801 ataacaaagt acaaggatgt cgtgatcaca ggcggaacca gtgtttggac ccagatacgc
    49861 aaatagcggt tcgtttcctt gatagctaaa ctttttaatg cagtaaaata aagattaaac
    49921 atttttctcc tccgtatgat tattttcttc tgtgattttc aaaaacagtt cttctaaacg
    49981 attcgactta ttcctcatag aaagaacttt gattccttgt cttgtcagct gatcgaagat
    50041 tccgttcacc ccttgatttc gttcaacttc gacagcgatt gtctgttcat cttcaaatgt
    50101 acaagcgtat ccttcaatca caggtttggt ctcatatggc gctaaatcaa agataaatgt
    50161 ttcaaattgc agtttggata gaagctcttt catactagta ttctcgatca gttcacctga
    50221 ttggatgatc ccgatgttgc gacaaagcat ttcagcttct tctaaataat gcgtcgtcaa
    50281 aatgatcgtt gtaccatttt cgttcaattc tcggagaaac tcccacatct cgcgtctcaa
    50341 ttcaatatcg actcctgctg ttggttcatc caagatcagc aaacgtggtt catgcatcaa
    50401 tgccctagca atcatcagtc ttcgcttcat tcccccggaa agcatacgtg cacggacatt
    50461 tctcttttcc caaagattgg actgcttcaa atatttttcg ctgcgtttca tcgcttcttt
    50521 gcgagagaca ccgtagtagc ctgcttgatt cacgacgatt tgctggaccg tttcaaaggg
    50581 attgaaattg aactcttgcg ggactaatcc aatctgttgc tttgctcgga ctagatccgt
    50641 atccagatca taaccgaaga cattcacttt tccagatgtt ttattgacta aagaagtaat
    50701 gattccgatc gttgtagact tcccagctcc atttggtcct aatagcgcat agaaatctcc
    50761 ttctttcacg gaaagatcga ttcctcgcaa tgcttcgacc ccacttccat aaaccttttt
    50821 caaattattt atttcaagcg catttgccat ttatttccta tctccttata gacatgattc
    50881 tttattgtat catggaatac agcagatgaa aaaacaactt ggttccagcg aaaaatcagg
    50941 ttgctgggct caggaaaatc tcctaatgaa agacatcaat cggacgaagt cagacaacct
    51001 tttcagaaaa aacaaatcga agataaagga ttactattca tatgtgcaac aaaaggagcg
    51061 tgagacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa cggcggaagc
    51121 aaaagccaag atttttgatc caataaatac tttcgatcac ttcgcctatc ccaatacatg
    51181 ccactgccgc ttttcatcaa ataacgcggc ttccgttttt gcggtttcta ctaaagtctc
    51241 tgggtaatcc aaaactttca gcaaggcaat cgcatttcgg gtccttgaag gtccttcttt
    51301 taatttgaaa tcaaaactga ttccttttcc ttctgttact tgttcttcaa agtggacatt
    51361 ctcacaataa ttctttaaaa tctctgtcaa ttcgatatca tgtgtggcga caaatgctaa
    51421 agatggatac tccgcaagcc accgaacgac tgaagcggaa gaagcaatcc gttcgatcgt
    51481 atttgtccct tttaaaatct catctacgaa gcagtagcag cgttctttgg aagccacttg
    51541 gtccaacaaa cgtttgatcg atttgatttc tgaaacaaaa taactgtcgc cttcaaataa
    51601 atcatcttcg attgccatgg aagtcaacac atgtccaggt tgcagggtaa actgttctgc
    51661 aatcgctgtt tggatcgtct gtgctagaat acagctgatg gctatacttt tgacatacgt
    51721 agattttcct gatgcattgg aacccgtgac taatgtattc ttctgccagt tgaccggatt
    51781 cactaccgct tcttttaaca atggatgata gatatctttc gctgtcacac cgccctcagt
    51841 aaactctggt cggcaagtga tgggcatata agtacggtaa ttcaatattg cagcggctac
    51901 ttctaattct cccagcaatt cccacagctt gatggcttca gttgaatgct tttctaattt
    51961 agtgagaacg aaatgatagg agataaatgg cagcatgaac atgatgttga catattcaaa
    52021 aatcaactct gcttcactcc cactcttcat acgaaatgaa aaacctaatt tagggatgtc
    52081 tcttaatggt ttagtttgct gtttcagctc ttcttgaagt ggtgtcggca gttttgctag
    52141 ctgattggcg gctgaaatcg ttgaaaccaa ataactcatg ctattcagct ctgtttctag
    52201 tgtttgtttc ttcactagat aatagaccgt attgaatact aacccaccga ttgccaaata
    52261 gattcctagt acttgtccta aaagaagcaa acccaaaccc accagcggaa gcaagccaag
    52321 aaaaataaat aaacctacgc gtccaatctt tttacttttt ccatccgcta gatattgttt
    52381 tgcaaaatta tgatcttttt ttcctaaacg agcgaattga tattggattt tttctctcag
    52441 ttgaggattt tcctgataaa aagcaatcag tttttctaac tgctgatctt caccaaaatc
    52501 aaagctgcgt aaacgttgat acaacgcttc tgaacctaca ctagaatagg tactgttgat
    52561 tccttcgaat acttcgaaca tatccaggtc ataccaagta agatcatcga tttcgctatc
    52621 ccatgaacgg aacttcttct ccgtgagcca tgcttccttc aagctttctt ctttatcaaa
    52681 tctcggttga taaggaattt tttcccattt gctacgaact gtttccttta atttcaaacg
    52741 tgaaaaaatg tctaaagcaa ctaataaaat aacagctgca ataataatta aaacgataaa
    52801 ttctctttga cccatatccc tctccgttcc tttatttgtt agctttagta tagcactgtt
    52861 gcgctatttg aaaagagggt aaaaaaacac ctttcaaaat aaaaggtgtt tttttcttgt
    52921 atattacata tttatctctc atttatcaaa attgacaaat aatcataggg aggaattgtt
    52981 gttaattctt gtttattctc cagtgcattg acaactgtcc caagggaaag gatagcctca
    53041 ggtactattt tttcttgttc tgttggatta gctaagcgaa gaacaaatcc ttgttcatga
    53101 aaataagaag gataaatcga tgatacaatt aagtcttcag gtaattcaat caatgaaaat
    53161 ttacgaggaa catcaagttc attttgtaat ggccaaatct tgttatctaa cctgtgaata
    53221 aatacattca gtttctgctt ttgataagaa atagattgtt ctaaccgttt ttctgcctgt
    53281 tttgccactt tgaactcatt aaatcttcct tcttctacat taaatccaaa agtgacttta
    53341 tactcaccta tctcttgagc tagcggtgtt tccatcatga catgcccttc atttgtcgta
    53401 tctcctgaag ctcgcccagg tcgccaagca agattaggtt ttccaagttc ccctgttgtt
    53461 gaaaataagg ttatgattaa ttgattttct atacgttcat actcttttaa accatctgca
    53521 taaaacgtaa aataatgatc attttctgcc acagagacac tcttatcgaa tatttctaaa
    53581 ttaacaggtt tctctaccat agtttctgac caattcggag gaatgacatc aggggtattt
    53641 tcaataaatc cgttttgaat ttgtgcaatt gatttttcag atttatctaa aacattaatt
    53701 gctaagcgca tacgatgcga gtaaacagta ttatgaattt tgagtgtgcc ttcaacgatt
    53761 tgactttctc ccagactgaa cgatatttca taagatattt cttccatttc gggtttttca
    53821 gataaacgat cttttaaatc tttaggaagt tgagcttttc cgtaaacaac taatgtttct
    53881 tgtaaagaat ctttatatac tttagctgtt tctaatttta gagatagttc tgtatctcct
    53941 tctaatggtg aataatcata cgtatcgcca tcatttgctg aatcgatcaa atgaacgaaa
    54001 tcaagatatt gtctatctcc aactatcaaa ttcaattgcc catctttaaa agaaagttta
    54061 tatttattgt tacttatctc agttttgtct atctcgattg ctgtttctaa tttttcatta
    54121 tttttctcaa attcaacaac agtgtatcct agtgctggca catttacatt tatttttatg
    54181 tcaagttcat aataagctgg ttcatcaaaa tattcgaaac ctgtagcaat catccgataa
    54241 gcatttttcc gttctggaaa ataaacttct ttttcaatga tattataggg actacctttg
    54301 aagtgtattt tctttgaatc agctactaca tgcacgattt tcgatccact ataattctca
    54361 gtcgttgtgt tgaaaacaag gacttcattc gattttagct ttaatgcatc agccatccgt
    54421 tttacaataa ggttttcgat tccgtcagct atctcattag cttctttgat tcgatggaaa
    54481 atatcttccg caacattatc tgaaacacag ccaccaatac tatcatgagc ctggttttgc
    54541 aaaatctttt tccataaccg acgaagtagg cctttactga tatggatacc atttctttct
    54601 gcaatcagca tgagcggctc aactcgtttt agaatttttt gttccaattt aaaattttct
    54661 attttcattt ttgttcttac tgagccaata gaacgatgaa cacgagagta aaccggctga
    54721 cgaagttcac ctttatattc aggtaattct tttttgtttc tgataacttc tacataagaa
    54781 ggataatctg aaataatatt gtggaattta ctgtatttat tcaacttctc tacgacttga
    54841 tcaaaattta aaatcattga cttttgatct acacccgaag gtactaaaat atctttgttt
    54901 tttccttgca tatgaagcat ttcaactgct tcatccaact tttcttttgc aaattcagga
    54961 atatctttaa ttgcgtctaa ggtcatcatt ccagtcatat aaccaaatgg aaaattcatg
    55021 gcataaacaa atttatctcc caatcctttc cagataaaat aaggagatgg aaccatcgtt
    55081 tcaaagttta atcctcgcca acacatgaaa ttatcgattt ctacttgatg caaaagtgta
    55141 ggcaaattcg cattgaaccc aaacgtgtca ggcaaatacc ctaccatcat tggatctcca
    55201 tatttaagga tcgtatcact gattccaatc attaagtttc ttaaaattga ttcagcatcc
    55261 actaataagg catctgtttg tgcataccac ggtcccacga atagttgtcc tgttttcatc
    55321 agtcgttgga taaccttaag cttttgcgga ttgatctcca aatactcatc gacgattgaa
    55381 gtttgtccat ctaaacaaaa gtttacttta gggttccttt ccaattcatc tagaacttca
    55441 gtaaagacct gatcagacaa tacgatggca tcttcatttg taaaatacca ttctctgtcc
    55501 cagtgcgtgt gttgaattat atgtgcattt accatatcag attctcctac tttccttctt
    55561 ctactgaatt tacttgttgt tcttttttat acttgatgga ttttagtgca ttgaccatta
    55621 acgctgtaac cactccccca ataacaattg atactaaata taaaggtata ttcgtaacaa
    55681 aaggaattgc cataaaggtt gaaagcattg tttcttgagt aacaccaaaa aatccattta
    55741 gaccacatgc tactgcagtg cccaccacga tgcttggtat tactcgtaaa ggatctttca
    55801 cggcaaacgg gatcgtccct tcagtaatcc ccacaaggcc cataatcata gctgtctttg
    55861 cattatctcg ttccgattca tcataaagtt ttttgtttaa aattgttgct aaaaacattc
    55921 caaatggcgg aatagcaatt cctaataaca tggctgtact aggtccaaag cttccgcttg
    55981 aaaaagaagc aaccccaaaa gcatatgcga ttttattgat aggtcctccc atatcaaacg
    56041 ccatcattcc tcctaaaata gccgacatca aagcagcatt tgctcctgac atgccttcta
    56101 gccaattagt cagtcctgtt gtcattgctt gaataggcgt agctagtaca taccataata
    56161 tgattccaac aactaatgta gtaacaaaaa ggaatcagca taattgattt tagactaata
    56221 acttgcatcg gtacttttac ttttttcaat gcattagcta aatagccaca agctaatcca
    56281 gcaaccattc ctccaataaa tcccatacca agattttgac acatcatccc agtgataaaa
    56341 gctggtgcta gaccgggacg gtcagcaatt gaatatgcga tataggctga aatcatcggt
    56401 acgataaact gtaatcccgt ctgaccaatc attcgcagga ctccccagaa tgtatccgtc
    56461 tggtcccaaa cacctgtgcc accaaaaatg actgcaatag aagttagtaa ccctgctgct
    56521 acgacaagcg ggatcatata ggaaacccca ctttggaaat gatttagaat ttctcttcct
    56581 tgtttcttga attccattag taactccccc acgatatatt ttttatttgt taattaatgc
    56641 aattgcttca tcaatcgtct cttcaccatc ttttactacc tctgaggtcc ctactgttaa
    56701 aatcggttta ccgtcaaagc gacctcgttc tgaaacattt gtatctactg caaatatgac
    56761 aacatctgcc tcggaaacat ccgaaattga aagtttgttt tctatcccca tagccccctg
    56821 tgtttctact ttaatatcta accctttctt cttcgcaaac ttttctaaat tagcttttgc
    56881 catataagta tgggcaatcc ctgcgataca tgctgttact gctactattt ttgtcatatg
    56941 aaattcctcc ttttaaaatg atagagcttt taccaattct tttttatttc tcgaatcttt
    57001 tattctttta acaaactcgt catccatcaa tcttccagat aattctgcta aaatacgtaa
    57061 atgattagta cctttatcag tgtcttttat tgctaacaaa aagacgagat caactggttg
    57121 atcatctaat gcgccccatt caacagaccg ctttaacttg gctacagcca ctgttgattc
    57181 aattactgct aggcttttgc catgaggaat ggcgatattt ttcccaattc ctgtggtcat
    57241 atggttttct ctgtcaaata cgtctttttg aaattgtttg tggtcagaca caaacccatt
    57301 agtctctaac aatttcgata atttttcgac tacacttttt ttatcagatg catttaaatc
    57361 tatcactata ttatttatat tgattttttc actgatcatt tataagcctt ctttcaatat
    57421 ataaactaat ttttcaaacg acgaactcgt ttttaaattt gctaataact catgattcga
    57481 agcgatttca ttgaatgttt cataaatttt attcaattca ggttttactt tttcattaag
    57541 tgcaaaaaag aaaacagaat gaacaagtgt cccatcccaa tcaattcctt ctggattaac
    57601 gtagacacag attactggct tttttataaa atctacttcg atatgcggca tagcaaaatc
    57661 attcatcgct gttgaagata gtttttctct tttgattgct ccctctagta tcccttcttt
    57721 cgcgtaattt tcttttacca attttttggt aattatattt aaaacgttca cttgattatc
    57781 ctttatttgg tgggtaaaaa agcaaaatcg tttatctaat aaatttagaa aagcatcttc
    57841 tgtttgttca tttaactgta gatactgttt tacttttctg acatctgccc ctaacatcaa
    57901 aggactaaca acaataacag gaaaatttgt attttcaatc ggaatcgtgc ttataacaag
    57961 ttcatcagtg acttttctat cttgtagttc attgatgctt agtacatctt ctatctcaac
    58021 catatctgca aaaccgttat ttattctttg ctctaataat tttgatgttc catatccgct
    58081 actacaaact aatatcactt tcgttttgtc aggtttgtaa cgatccaaaa gtgattgaat
    58141 atggagtgtt acgtaagcga tttcatcttc attaaaatgt atacagaatc tctcttcgat
    58201 ttcctctaat aaatctacac ttatcataaa tgacctttta aaagaatatt tgattttgtc
    58261 cgtataaggg ttatagatat ttactcccaa tttgagtctt ttaactgctg cattgagatg
    58321 taatactaga ttattgatca attcttcatc aggataaaat tcatttaatt taattcttac
    58381 taactcttgt agctcaacac ccatatctaa ataggaaagc ttcgtttgat ctaagtcgtg
    58441 attcatagca tttttttcaa tcgaagtaat gtgaatgtca acataagctt gttcatctat
    58501 tggcacaata attgaaaatg ctttttcaat cattttgatt aaaataagtg tattctttga
    58561 gatttcttct tcagaattat tactacgtga taagaaattg cttgtttcaa tcctttctat
    58621 cgcaatagca aggtggatag ctaaagtttg aaattcataa tctgtaaatt tcaattgtgt
    58681 cttattcatg tatcgattaa gcaattcggc tacttttttc aatatgtcct tatttaagaa
    58741 attattcgct tcaccaatga aattgatatt caagtctaag agatctgttt tactgttaga
    58801 tgctgtaaag ccaccccaat aatagttcac aacttctgac atcaaccttc ttttactttt
    58861 ttcatcagct ttgatgcgca cgccatttcg atctgaaact aaggacatcc catgcttgtt
    58921 tagtcttttt ctaacatctt tcattgtgct ttctaccgtc gacctgctca cgtataattc
    58981 gtcagcaaga ttttgaatct ttagagaatc attagtattc aataatttag caaacacata
    59041 agttagacgg tcctccggag agtctgcgat attgatttta tgactggata ataaatttcg
    59101 aagtgtttct ttttttccaa taagcgaaac gcctttttta ggttgaacca acatttgtac
    59161 atctggcatt ttttggatta tttctttcaa aattaaaata tctttgctaa ttgttttcgt
    59221 agatacatat aattgttctg ataattcttt gtaagttgtg tgctcatttt caatcaaaaa
    59281 gtatagtatt ttcatttgcc gttcgctaaa ttcgatgccc attatcttca cctcctgaat
    59341 acagcttaag tgtacaatta ttatctctat tttcatacag aagaaagttc ttgattaatg
    59401 tagaagtttc taatattctt gattatttca aatcaataaa aaagcctgca atatttatat
    59461 cacaggcttt tttctctatt aaatatatat aagataatac atttttctac tagttctcac
    59521 taatcttgta taattaaacc ctccgcaact tgacggagat ggagaagatg cccccgtcta
    59581 atctagcggt catctctcct cccattcctt ccaccaattt ttttgacagg taaagcccga
    59641 ttccgctaga ttccgtattt gtgcggctgg tattttcggt ataaaaacgc tggaagactt
    59701 tttcaacaga ggtttgcgtt cctggtttga taggattggc cactgttaat cgaatgaatg
    59761 gatcctcttt tgaaaatgtc acctttgctt gtccatctgc ataacgcaat aaattctgta
    59821 tgatattttg cagcactcgc agcaacatga gcggatctgc taatacagtt gtatttatcg
    59881 agtgttcagc gaacgctacc tcgatatttt tctcagaaaa ttgttcataa aaagagaaaa
    59941 atacttcttc cacctcttta gaaaaagaaa gcgtatggag atccatttct ttttgcttcg
    60001 tctctattcg agcaagatca taaaactgat ccgtcatact gagtaatctt gcaacagatt
    60061 gtttgatgat cgttaaatac ttctcccgtt tctccgtatc ctctacctgt tccagtaatt
    60121 gtacataacc gttaatagca gtcaaaggag ttctgagatc atgagaaagg ccgacgatcg
    60181 atagtctgat gttttcttcc atttcttgaa atgcttgtcc tttttgttca ttttcatcca
    60241 accatgtatt cagtgcatct actaggtcca ttagattctt ttctcgaaat tcgactgaaa
    60301 gacgaccacc atattcttgt cgttcagaaa gagtggcgat tttcttagtt aatctcttga
    60361 tttccctttg caggaagaaa ataaaacttc ccataaagat aacaacgaga agcaacagcc
    60421 atttaatcaa atctaaaccc cactccccac accgtatgaa tatacacagc atgtgccttt
    60481 gctagcttcc ctcgaagatt ggaaatatgc atattcactg ttttctcact atcaaaatat
    60541 ggttcttgcc aaactgtttc ataaagattt gctcgcgaaa atactttttt cggatgttct
    60601 aaaaaaagct tcagcagatc gaattctctt cctgtcaaat ggacagccac accattcaca
    60661 tttacatccc tcgactcttt gtccagtaag atttccttgt aatagatgcg ttgcgacaga
    60721 tcttttactt ggacagaagt ctgatgacga agttggatgc cgattcgtaa caaaagttct
    60781 tcgatatcaa atggtttcgt cacatagtca tccgctcctg ctgccaacaa ggaaacttta
    60841 tctctttgat cgctttttgc tgaaagaacg atgatcggaa cattcgatgt ctgtcggatt
    60901 tctgctaaca atgcttcacc tgaaagccct ggaagcatga gatctagaag gatcaaatcg
    60961 acaggatatg tgcttaacaa taattttcct tccgtacctg aataagcatc aagaagtttg
    61021 tatctctgtt caagaacctc ctccagtaag gaatgaacag cttcatcgtc ttcgataatc
    61081 aaaatagttt ccagcaggac cacctactta atgtcagatt tttggaaaat aaacattcct
    61141 agagctgatg ataccacgat tgttactaga ctgaccagaa tcattttcgg tgcttgcgaa
    61201 taagttgctt gttgcgcaaa gtccgtatac atgagccacg tttccgtaaa ccactccgtt
    61261 agaaattcca agcctttgat ttttgcgaaa acaccgggaa tgaaggccgt tcccatgata
    61321 taaagaaaag aaagaagcaa actgacactg gtacttctag tgatgaatgt caaagccact
    61381 ggaacagata atgtccctaa tgtcagcaga agcaatacag gaaatacttt tagaacataa
    61441 tttccatagt ttttgattcc ctcaacttca ccaaatccga aagcaagtgt gtaagcaagc
    61501 atggctagtc ccgtgatcaa aaccacgcca agtgttgtga tcaaaagcgt aacgagaagt
    61561 ttcgacacat aataagtcat tcgattccgt cctaaagata acgtattgcg aatcgtaccg
    61621 ttttgaaatt cttccccaat ataaaagcac gcaaatgctg cgaaagccag aagaatccat
    61681 gcagccattt tttctaccat taaaatccct gttgcaccgt tgatgactgt atccgttgct
    61741 tggtttaatt cattgccgta ttttgtatgc atataccatt cgttccaaga ataaaaaagc
    61801 ggaagtacga ccatcagtcc tagtgagacc cacattttac ggctcttcca tacttttatt
    61861 ttttcagcag ttaatagatt aaacatgtgg attgcctcca gttaattgta agaaataatc
    61921 ttccagtttt tgcccaacta ggtgaatacc atccacagga acttttgctt ctaccaatgc
    61981 ttgattgatg gctgctactt ggtcaattcc ttcaaaaagc tggataacac ggctagattg
    62041 tacaaaataa tccctataac caagagagtc gagaaccgtt actgcttgtt ccgtcgccga
    62101 agtgtcaatt tttataaatt gacgagattc ttgtgccaat tcttctttcg ataattcttt
    62161 gatcaagtgt ccttcatgca aaataccata gtgagtggcg atctgtgaca attcatctag
    62221 caagtggcta gaaagcaaga cggtgatgcc ccgttctttt accaaacgtt ggatgatttc
    62281 tcgcatttct gccatccctg ctggatccat cccattcgtc ggttcatcca aaatcaaaaa
    62341 ttctggattc gtgatcagtg catttgcaat agctaaacgc tggcgcatac ctaaagagaa
    62401 attctttgct ttctttttcc ctgtattttc caatcgcatc attttcagca ggtcttcgat
    62461 ttctctatcc gacacaccgc cgttcgctgc ttggatacgt aggttatctc ttgcagttaa
    62521 ttctggataa agagcagggg tttcaatcga ttgacccata cgtcgtcttg ctgcctgcaa
    62581 atccgtcgtt ccaaataatt cgatcgaacc ttcatcaatc gagatcaaac ccataatagt
    62641 tctcataaag gtagacttac ccgctccatt ttccccaatc aatccataga tcattccacg
    62701 tttgatttcg attgatactt tatctaatgc tttggcagca ccgtattttt tggttatacc
    62761 agttgctttc aagaccgttt catttccaaa atccatactt atccttcttt cttattgatg
    62821 agtgaagtat agttgacggg tataaagaaa gcagccagaa atgtataaag aaagtgtaaa
    62881 ttttccaatt gaatgtcaaa aaaaacaatc ggacaatacg tgtctttcct attatcaggc
    62941 agtttgttat acgcttgtat cagtttcctg attctttctt ttcgaccaaa gtcgtttctc
    63001 tgtattcctc ttcactgaaa atttttgctt ctttcagatc aagcttgagt aattttacca
    63061 gaccggttat aaggataact atagcaagac tccctcccag aaaaattaga ctgtctcgca
    63121 gacgtggttg cgttgtcttc caatcaaaga gcgcaccaaa cagtgctaat ccaagtggac
    63181 tggccaccat ggtaatcgtt gttatcgttg acataagtcg tccttgtata tgcgttggaa
    63241 cttctcgctg aagccagacc atataaaaag caaaagaaaa cattaatcct taaaaacgga
    63301 cttatgaaaa ataatacatg ccgtttggga tttacaatta gctaccaaat aagaggttat
    63361 gacaaaagac ttttcacaat cccttcttcc gaataaacgg tgttctcctg ccaactcctc
    63421 ggtcacaagt cacaatattt atcaaacatg agaagcaatt tttgtaaatt ccttcttatt
    63481 tcttgaagct gaccacttct gtcacaacct cagaagcgga taaataatat tgtttgatga
    63541 tactttatct ttttcccgtt tgtttataga tcgaatgata ttatagacca agaatcctac
    63601 ctattaacat agctaaaaac acaaaaaagg cactttccaa attgtggaaa gtgccagaaa
    63661 agttaggatt aaggtaactg cgctcagcat tgcttcgccc agtacgattc tcgtaactcg
    63721 tgaactcgaa cgataatcgc aattaacgtt ttgagaactg tgaagcttta cgggctttct
    63781 taagacctgg ttttttcttc gtatcattga ataagtttga aaaaccttga tttataaagg
    63841 ttttcccgta aatatatttt attatatttg attaaatttg aaatgtttgt gttctaaaat
    63901 gtgttctaat ttaaaggcag tatatttcgt attttagatt aaatttttag gctcattcat
    63961 tctcaaatcc attctattca gtcaataaaa attttaaaaa gactttataa acaaagatgt
    64021 tcaagcgagc atcttatttt tttgtgctta atttgaaagg agaacatttc atgtataaaa
    64081 aacaaaaaaa gaaattatgt gtattaacta ttttgagttt ggctgttcaa gcaattgttg
    64141 gagcaattgc tcctacgatt acttttgctg atgaaattac ccatccacaa acggtaaccg
    64201 tagaactaga tttagcacat caatatgctg ttgaaggaac ttttagtgat ggtcgtccaa
    64261 tgtcagaagt cactgttccg cattatgcag tgtacaacgg ctttaaacaa gatattttct
    64321 gtattgaacc aggagtcccg atttacaatg agttcactcc tggctatgag aaaaacccgt
    64381 taccagatat gtccgataaa gccaaattag tttccgtttt atggaaaaaa gtaggtacag
    64441 atgcagatac tcatattgtg gcacagaaga tgatctggca agaagttaat gggtataccc
    64501 ttcactcaat aaaacgatca gatggtagtg ccgtaaatat cgcagccatt gaggcaaaaa
    64561 taaatcaagc cattgacgat tatcagaaga aaccaacctt ccataatagt acggctaaaa
    64621 cagtattagg gcaatcgact actgtgacgg atacgaataa tctgaatttg tcagagttcg
    64681 atgaggttgt ggaaaatgcc gcaaacattg attatcgtgt gaatggtaat cagttgataa
    64741 tcaccccaaa tgccaattca aaagaaagtg gtgtgctgac gcttaagaaa tctgctggta
    64801 ccggaacacc tgtcgcctat aaaaaggctg gccaacagac tttaatggcc ggggcgattg
    64861 ataaacctaa tacctacaca atcaaaattg atgtggaaac ggagggttct ttaaagatca
    64921 aaaaagtcga taaagaatcg ggtgatgttg taccaggaac ggttttccat ttagactttg
    64981 gaaaaacttt acctgcaaaa gacgtgacta ctgacaaaga aggcattgct acattggatg
    65041 agattcctca tggtacaaaa gtaaccatta ccgaaaaatc agtaccggcg ccttatacga
    65101 ttgataccac ccccatgact accaccatta aagcaggcga aaccatttac gtgacttcaa
    65161 aaaacgcacg ggaaaaaggg caaatcattc tggataaaag cggagttgaa acagggagtg
    65221 atctttggaa tgacaattat tccttagctg gtaatacgtt tgccattcgc aaagacagtc
    65281 caaccggtga aatcgttcaa gaaatgacca cggatgaaaa cggtcatgcg gaaacaccaa
    65341 aagagattgc taatgcgttg gaattgggaa cctattatgt gaccgaaact aaagctagtc
    65401 atgggttcgt gaatacgttc aaacctgtaa aagtcgaatt gaagtatgcc aatcaaaccg
    65461 tagcccctgt taccagtaac gtaaaagggc aaaatcaaga agtcactggc gaaaccactt
    65521 tgacgaaaga agacaaagat actggggata aagcacaagg taaggcagtc tttgagggtg
    65581 ctgaatacac cttgtttact gctaaggatg gaaaagctgt taaatggagt gaggctttta
    65641 aaccagagtt agcgaaggga acgaaaggtt ctgatgaaac ggtcactttg actttagacg
    65701 aaaagaacca agttgccgtt aaacatttag ctatcaacga gtattattgc caagaaacaa
    65761 aagcgcccga aggatatagc cttgatgaaa caaagtatcc tgtatccatc aaaaaggtgg
    65821 atgatagcga aaaaaatgcc gtgattaccc gaaatgttac ggcaaaagaa caagtgattc
    65881 gctttggctt tgatttcttt aaatttgctg gatcagctgc gggcactacc gaaactggct
    65941 tcaatgatct gacctttaaa gtgtcgccat tggaagggac caatgaaatc acaggtgccg
    66001 aagatgaagc gaccacagct tataacgagc aattagggtt tgatggttat ggcaagtttg
    66061 aaaatcttcc ttatggggat tatttacttg aagaagtaga agccccagaa ggttttcaaa
    66121 agattacgcc attagaaatc cgttctactt ttaaggaaaa caaagaagac tttgtgaaga
    66181 gtgagtatgt ctttaccatt accgaacaag accaaaaaca accaattaaa acggtgaccg
    66241 ttccttacga gaagctgacg aacaaagcat tttctgttag tttgaaccgt ttaatgctct
    66301 atgatttgcc tgaggaagaa gatagtttaa cttctcttgc gacttggaaa gacggaaaca
    66361 aagaattaac ttctctggat tctaccgagc tagttgataa attgagttac aatctacatg
    66421 aaatcaaaga agactggtat gtggtagcgc aagccattga tgtggatgcg acaaaagctg
    66481 cccaagaaaa agatgaaaaa gccaaaccag tggtgattgc agaaacaagc gcaacgttgg
    66541 cgaacaaaga gaaaacagga acttggaaaa ttcagcataa attaaccgcc gaacaagttt
    66601 taaataaaac tattgtctta ttcaactatg tgtatgaaaa taaggaagct tttgaagcag
    66661 gcgataagcc agtagcgaag gatgttagct tgaataacca agcccaaact gtcagttgta
    66721 cagtggaaca ccatgtttct atccaaacaa aggcccacct agaaaacggt tctcagacct
    66781 ttactcatgg tgatgtggtg gatatgtttg atgatgtgtc gattactcat gatgtactgg
    66841 atggctcaaa agaagctttc gaaacaattc tgtatgcttt attaccggat ggtacaaaca
    66901 aagaaatttg gaaatctggc aagattgatt atgaagtaaa tgataaagaa ttcaccaaaa
    66961 ctgtgcttgc gaaaaaagta gataccggaa aatatccaga aggaaccaag tttacttttg
    67021 cggaaatcaa ttacgataaa gatgggaata tcaatggaaa acacaatgaa gatttgaaag
    67081 aaaaatctca aaccttaaca ccaaaagaag ttccaaccat actaagtacg ccgaaacaac
    67141 cggaaacacc aactgttcca agtggctctc aagaatctag tcccacagtg aagaccttcc
    67201 ctcaaaccgg ggagaaaaat tccaatgttt tactgttcat tggttttact ttgatttttg
    67261 cgacggcggg ctattatttc tggaatcgcc ggaactaagg tgatgagatg atacaagtaa
    67321 atcctaagaa ccaacgtgcg cgaccgcctc ctaaaaaagt agtcgcgcta tttttgtatc
    67381 caaaactaac aatgaaaaga ggaaaagaag atggaattga aatttgtcgt gccagatatg
    67441 gctgaaacct ttggaaagtt aagttatgcc ggtgaaggag aaattataac agaaggatat
    67501 ggacggaata ctacggtgat tggtcgcagt tatcatttgt attccagtaa gcaacgggcc
    67561 gatgatattg aggtggtagt agctgcggaa gccggtgaaa aggattttga tcaagaccaa
    67621 ccgctaaaag ccgtgaatcc ccatttggtt gccaaaggct atgagattga gaatcgtggg
    67681 tttactgatt acgtgttgta tgttgatgat ttagtgaaag cataggagga aaagaagatg
    67741 agattaacag aaggtattgt cgtagattca ggtttaacat ttgggaagtt gcgtttttcc
    67801 gcattacgcc gagaagtacg gaagcaaaat gaggatggaa caattggtaa tgaggtaaaa
    67861 gaacgaacct ataatttaaa atcctctgca caagggcgaa tgattcaagt tagtatccca
    67921 gctaatgtac ccttacgcga gtttgcttat gatgcagagg tagagttggt caatccaatc
    67981 gtggataccg ttgccaatta tgtttttcga gaaggaacta ccgttaattg gttcattaag
    68041 gcggatgatt tagtcttgaa gcggcagccg aatcaaggaa atcctacgaa ccaaaatgaa
    68101 agaaagaaat aggtgaagat tatggaaatt aatgttgaac atattttaga ttgtctcgat
    68161 caatatggaa aaggcgagct gactgaggaa caactcgtta aagcattaac ctctgatgaa
    68221 aaaatgtttc tgattataca tcaaggttta cttggagaaa atagcgacag tgaagaagac
    68281 tctgatgtac tagactggtt aggagaagaa gagtctttct ttatagttgt cgaagtaaat
    68341 gaaaacttat gtcggcaggc agaatccatt ttggaagaaa ttggtgtgga gatgccggat
    68401 gctattgaag gctttttaaa tcaattggtt gaaacgaaac aactcccctc ctcgtagcag
    68461 taaatgacta gcataacttt ttgaaattgc ctaatgaaat cctattgggc tttttcgatt
    68521 ggaggtggaa accatcaaaa tgtacaaagg acatcgcata cgcgcaggag atcagcactt
    68581 ggtttatcac tttgttattg gctggctact cgctctgttc atcggttgga tgagcgtctt
    68641 ttattttcaa gagtttagac aatttgatat ttctaagcta tcactttcta ctattgaaat
    68701 cgtttggtct ataaaagatt tagtatgtct gcttggaagt ctcgcttttt caggagctat
    68761 gatattgctt tatattcact tttttcttga tcattggcga agcttgtggc atcgacaaaa
    68821 gctagctcgg atgattctag agaaccattg gtatgaagtg aaacaaactc aaagtgaagg
    68881 ctttttcaaa gatttgaata gtagccgaac cagagagact atcagttact tccccaaaat
    68941 ctgttatcga atgaaagatg gattactgtc tattcgcgtt caaatttcac ttgggaaata
    69001 ccaagatcag cttttaaaat tggaaaagaa gttagaaagc ggactgtatt gtgagttagt
    69061 agaaaaggaa ctcaaagact cctatgtgga gtatacttta ctgtatgata tgatcgccaa
    69121 tcgaattggg atagacgaag tagtggcaga aaatgggact ctgcgattga tgaaaaatca
    69181 agtatgggct tatgattctt taccccatat gttaatcgct ggtggcacgg gtggagggaa
    69241 gacctatttc ctcctcacca ttatcgaagc actattgaag tcagatgcag aattgtttat
    69301 cctcgatccc aaaaatgcag atttagctga tttaggtacg gtgatgcctc atgtttattc
    69361 acaaaaggaa gaaatttctg cttgtgtgga agatttctat gaacgtatga tggctcgtag
    69421 caaggcaatg aaagaaatgt ctaactacaa aacaggagag aattatgcct atcttggact
    69481 tccacccaac tttttaatct ttgatgaata cgtggcttat atggagatgt taacgacgaa
    69541 agaaagtgcg gtgattttga ataagctcaa acaaatcgtg atgttgggtc gtcaatctgg
    69601 tttctttctg attttggctt gccaaaggcc ggatgcgaaa tatttaggag acggaatccg
    69661 cgatcaattc aactttcgcg tggctttggg tcgtatgagt gaactcggat attccatgat
    69721 gtttggggag gtcgaaaaaa acttctttat gaagcacatc aaaggtcgag gttatgtgga
    69781 tacaggtggc agtgtgatta gtgagtttta tacgccactt gtaccaaaag ggtatgattt
    69841 cttagattca attagtaaat tagaaaagat gaatgattga gtgatcttca atactgactt
    69901 tatacttcaa gtaacgtata atacttttat atagtaggaa gaaaggggat aattaatatg
    69961 gaaagtaatg attcttattt agagtatgca aaagcaaata aggataagtt tatttcttat
    70021 attatcaaag ggaaatcccc cgaagttgga cgagacgcag tttttatggc agggagtcct
    70081 ggggctggaa aatcagaggt tgccattgga ttagctgaga attatgataa ccatgtgatt
    70141 attgatgcgg attactttcg cacccagttt cctgattata atggaaaaaa ctctagtctc
    70201 tttcaaaaag catcttcttg gttggtagag caggcattta gatatgtctt agatcatggc
    70261 tattctttta ttctggatgc aacttttgca atattaagtg ctgaaaaaaa tatctcgcgg
    70321 gcgttgaaaa aacattttcg agtgacgatt ttctatgttt atcaagaccc taaaatcgct
    70381 tggaaattta cacaagaacg tgaaattgca gagggacgtc atgtgccgaa aaaggcattt
    70441 attaacgctt ttttcaaatc aagagagaac attgcaaaag taaagagtaa acatccagat
    70501 gtattgcttc atatcataat aaaagattat acgaataata tttccgaagt tcattatgct
    70561 acggataatc tagaattatt tttaccacta gggtatagta ggaaagattt ggaggttcaa
    70621 ttacatgact gagaaagaac aagtaacgaa aattgtaaag aaatacaata agagcattgc
    70681 ggatttatcg gaaaatgcta ctgcaaaaga gttcaaaacg gtgattaaat atgtagccga
    70741 tcaggccaat gaaaaacaac ggaaattagt tggattaaat aaaaaatagt aggacaaatt
    70801 aataatgtat gagccaagag caaaatgttc ttggcttttt tctttgcaat gaatgaggta
    70861 atgtatgaga tttttagatt tattcgccgg tattggtggc tttcgtttag gtatggaaca
    70921 ggcgagccat cattgtatcg gtttttgtga aattgataaa tttgctagac gtagttataa
    70981 agcaattcat gatacaagta aggaggtgga aatgcatgac atcacaagtg tatcagatga
    71041 gtttattcaa tccctcggac cagtggacat cctttgcggc ggatttccgt gccaagcttt
    71101 ttcaattgcg ggaaagcggc aaagattttc cgatactcga ggtactttat tctttgaaat
    71161 cgctcggttc accactcttc tccgacctaa gcttttattc cttgagaacg tccgaggatt
    71221 gctcaatcac gaaggagggg ctacgttcga gacgatcctc cgaacgctgg atggattggg
    71281 gtatgacgtg gagtggtagg tgcttaactc aaaggcctac attccccaaa gccgggagcg
    71341 gatattcctt atcggacatt ctcgagacgc atgtaccgaa caagtatttc ctatcattgg
    71401 accgtcttca acatctgatc aaaacatcag aaatttggta aatatcaatc cttccaatcg
    71461 aggaatgggt ggacaagtct atggttcaga tggcgtagcg ccaaccttaa caggtgatga
    71521 aggaatcaaa atcgcactgc cagcaaggga tggaatctct gtagcaggac tattaccggg
    71581 aaagtttgaa caaggtaatc gagtttatga agttactgga accgccccca ccttgtcaac
    71641 gaaacaaggt ggtacaaaaa tcatgattcg aaaaaatgaa acagaatatc aagaggtgaa
    71701 gccagaagac agtgtgaatc tggcttttcc taattccaca agtcgccgag gtcgtctggg
    71761 aaaacagagt gttcatacct tactaacagg agaccaacaa gcgatcgtca cggatcagta
    71821 tcaaattcgg aagctaacac ctagagagtg ttggcgactt cagggctttc ccgattgggc
    71881 ttttgatcga gattctcaag tcaattcaga tagtcagttg tataagcaag ccggaaactc
    71941 tgtaacagtt ccggtcattt ttgatattgc cagaagatta aaagagttgg atgtacatgg
    72001 tttatgatga gttgattgga gaaatttatt gggtgattgg aaagattcag tcagacccag
    72061 aattagaaga acaattgcga cggttaaaat ttgatattcg caagaatggt gtcaaagtcg
    72121 ctggcgatcc atatttaatg aatgaggaga cggatgctcg aattgaaata aatcaagtaa
    72181 ttgcagaatt tgagcggatt gcggaccaag caaaagaacc agatattcgt caatacttgt
    72241 tagaaatgaa agcagagttg gaagtaaatg gtattacaga tgagtaacct aaaccaacac
    72301 aactgactgt taggcgctga ccgcggagga ttcgcgaagc agaaatcctc cgtggtgctg
    72361 tgcctgttca tggacggcgt tagccgacca tgatgtctca cccccgtatc taacaggggg
    72421 gtacaaaaac acaaaaaata agtaagcaac cattaagaat gcttgttgta tcaaagatag
    72481 taagtaattt gtataggtgt taactcattt gaaaaagtta acaccttgaa tttggaggtg
    72541 agaacttggc acaacggaat ttagattatc ggctattaaa agaccgacgc aacgaatacg
    72601 gcgtttcaca aaataaattg gctacggctt gtggacttag tcggccgtac ttaaatcaga
    72661 tagaaaatgg tggcgtaacc gcatctataa aaaccatgag gaaaattttt gaccaactgg
    72721 aaagctttaa tcccgatttg cctttgacgt tactgtttga ctatgtaagg attcgctttc
    72781 ccacaacgga tgcacgaaaa attattcaag aaattctcca tttgaaattt gagtatatgc
    72841 tccatgaaga ttatgccttt tactcctatc aagaacagta tgtcatgggt gatattgtgg
    72901 tgatgttgtc tcatgaagaa gataaaggtg tgcttttaga attaaagggg cgaggttgcc
    72961 gacaatttga aactttttta ctcgctcaaa agcgtagctg gtacgacttt ttcgaggatt
    73021 gtctaaaggc cggtggcgtg atgaaacgct tggacttggc aatcaatgat cgagtggggc
    73081 tattggatat acctgagcta acgaaaaaat gtcagaagga agaatgtatc tccttgtttc
    73141 gtacctttaa aagttatcgt tccggggaac ttttaaaggc tgatgaaaag gacggcatgg
    73201 gcaatacctt atatatcggc agtctcaaga gtgaggttta tttctgtttg tatgaaaaag
    73261 actatgaaca atatatcaag ttagggattc cattagacca aactgagacg aaaaatcgtt
    73321 ttgagattcg actgaaaaat gaccgtgctt ttcatgcgat tcaagatttg ttaaaaggtc
    73381 gtagcattga gagcaccacg ttttccatta tcaatcgtta cttgcgattt gcggataaag
    73441 tagaaggtaa aaggcgaacc aactggccct tgaatgaaca atgggggcgt tttattggac
    73501 ggaatcggaa agagattcaa ttaacttccg agccaaaacc gtataccatt gaacgaacct
    73561 tgaattggct aggccgacaa gtcgccccta cgtggaaaat ggctaaggag ttggatcgat
    73621 tgaatcggac aacctatatc caggatatgg tacagaatgc acgcttatca gaccgacata
    73681 aaaagatttt ggagcaacaa agtatggcaa ttgaaaattt gattatatga aaagaggaat
    73741 cgtcatggga attgtaaaag atattttttt ggtatttggt ggcagtatgc ttggtgttac
    73801 tgtgatgtgc ttgatgaatg caagtgcagc agcggatcga gcaatggaaa agaaaggaaa
    73861 gtgacaagat gaatttcgga caaaatttat gtgcgactcg ttccttagtg aaaagctaag
    73921 gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct gacaggtgga
    73981 atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt gtatgaggaa
    74041 actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag ttgatgaaca
    74101 tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt cgggggtcta
    74161 taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa tgtacgggtc
    74221 taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg tggcaaagta
    74281 agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca gcaggcttat
    74341 agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg aaaggtattg
    74401 ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta atgctgaaaa
    74461 gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct caagtcgtgt
    74521 atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata aaaaagctca
    74581 ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa acattgtgtg
    74641 tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat gatttatatg
    74701 ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta tcgagagaaa
    74761 atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca gcaggaacag
    74821 acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc aaaaaagtaa
    74881 gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg cgaaaagaaa
    74941 taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg gacaggctta
    75001 tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt agtgaaaaca
    75061 gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc tataaccgcc
    75121 tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc tttgacaacg
    75181 tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac aagcacttga
    75241 tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt acaataacat
    75301 atccagagaa aggaactccg caagggggaa taatatcccc actactagca aacattgttc
    75361 ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt acaaaaaact
    75421 atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac aaagaaatga
    75481 agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt agagttttct
    75541 gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg attgaacaac
    75601 gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga aaaagatact
    75661 ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta gttgttaaat
    75721 cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca caggcaaaga
    75781 aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt tataattcaa
    75841 tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg gattgtatga
    75901 aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac aaaaggggca
    75961 gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat ggtaaatcta
    76021 aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga tatatccaac
    76081 acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag ggaagaaaat
    76141 ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg aaattatctt
    76201 tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct gctcaacatg
    76261 gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat tgtcatcata
    76321 ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg gtaaaagagg
    76381 cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat atagctctat
    76441 tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta gctggcaatc
    76501 aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa cacgatggaa
    76561 cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt tgagatattt
    76621 ataatatcag gaacttacct atccatatat caatggtttt taaccaatgc ccaatcctta
    76681 gtcttactgg caattgtggt cattggtttg tttttaggat ttaagcggga gttttccaaa
    76741 ctgattggct ttttggtgat tgctttgatt gcggtcggat tggtctttaa tgcttctggg
    76801 gtgaaggatg tcttactcag tttgtttaac cgaattgtcg gtgcgtaagg gggaagcacg
    76861 atggaacaga tgcgtgttta tattgcgaac ctcgggaaat ataacgaagg tgaattggtg
    76921 ggggcgtggt ttaccccacc tgtcgatttt gatgaagtga aagaacgaat tgggttaaat
    76981 gacgaatacg aggaatatgc aattcatgat tatgaacttc cctttgagat tgatgagtat
    77041 acgccaattg aggaaattaa tcggttgtgt ggcttagcgg aggaacttga aggaacgcca
    77101 gttggtgaag ttgcttctga gattcaacat gctttcttca attcttttga ggagatggta
    77161 gagcatgtgg atgatattat ctattatcca gattgcgatg atatgagtga tgtagcatat
    77221 ttcttgattg tagaagctgg tgattttgga gaagtaccag aacacttgaa gacgtatatt
    77281 gattttgatg cgtgtggtag agacttggag attggaggca attatttggt aacgagtcga
    77341 ggtgtttttg agtatccata ttaacaaaat tattgaaggg tagttgattt ctaaactatc
    77401 cttcttttta aaggaatgat ttgatgaaga aaataaaaag ctacaccagt atttgggcag
    77461 ttgaaaaggt catttatgca attaatgact ttcaactgcc ttttcctgtg acttttaacc
    77521 agatggcttg gtttgtttta tccttgctgt ttgtcatcgt atttgcccat gtgcctccac
    77581 tatctatgat agagggggcc tttttaaaat acttaggtat accggtggca gttacttggt
    77641 tcatgtcgca aaaaacgttt gacggtaaga aaccattggg atttttacga tcttttatta
    77701 gctatcactt acgatttaag gtcactttcg caggaaagaa agtcaaagaa cagaagaaac
    77761 gatgggacga acccattact ctggtaagga gtgtgaacta tgtacccgat taagtatatt
    77821 gaaaataatc ttgtctttaa tcaagaggga gaatgttttg cctactatga gttaatacct
    77881 tacaattact cctttttgtc acctgaacag aaatatcaag tccacgataa ctttcgtcaa
    77941 ttgattgcgc aaaatcgtga aggcaagatt catgccttac aaattgccac agaaagtagt
    78001 attcgtgcca cgcaagaacg atcaaaaaag gaaattaccg ggcgattaac agaagtagcg
    78061 aaacaacgaa ttgatttaca gacagaggca ttagtatcca tgattggcga tagtcagatt
    78121 gattatcgct tttttattgg cttcaaactg attgcgacag atgaagaggt caatctaaag
    78181 aatctcaaga aatctttctt ctccggcttt caagaatttg tctatggagt gaatcatcat
    78241 ttgatgggcg attttgtttc cttatccaat gaagaaattc gccgatatac caagcttgaa
    78301 aaactaatgg aaagtaaatt ggctcgaaga tttaaagtca gacgagtcac accgagtgat
    78361 ctgatgtatt tgattgaaca tatctatggc gaaaagggta caccatttga agaatatgaa
    78421 tttcagctac caaagaaaaa gctgaagtcg gaaactttgg tgaaacgtta cgacttatta
    78481 cgtcccagtc gttgtttgat tgaagaaaag ccccggtact tatgcatgga acatgagaat
    78541 catgaatcat atgtagcgta cttaacaatt aatacaattg tgggggaaat ggagtttccc
    78601 tcctcagaac ttttctatta ccagcaacaa caatttacat tcccaattga cactagtatg
    78661 aatgtggaga ttgtgacgaa caaaaaggca cttgctaccg ttcgcaataa gaaaaaggaa
    78721 ttaaaagact tggacaacca tgcctatcaa tctgacaatg aaacaaattc caatgtctta
    78781 gatgcattgg attccgtaga tgaattggaa actaccttgg atcagtccaa agaatccatg
    78841 tacaaactga gctatgtggt tcgagtaagt gccgaatcag tagatgaact aaagcgccgg
    78901 tgtgatgaag tgctagattt ttatgatgat accaatgtaa aactagtccg gccttttggc
    78961 gatatgatgg ggctacatga agaattctta ccttctagta agcgatacat gaatgattat
    79021 atccagtatg ttacgtctga ttttctcgcc ggacttggtt ttggcgccac tcagatgtta
    79081 ggggagttgg aaggcattta ctttggttat aacgtagata cggggcgcaa tgtttacctg
    79141 aaaccggcat tggcctcaca aggggtcaag gattcagtta ccaatgcgct agcagcggca
    79201 ttcctcggtt cactcggtgg cggaaagtcc tttagtaaca atctcttagt ttattacgcc
    79261 gtcctttttg gtggacaagc tgtgattgtc gatccaaaag gggaacgggg tggctggaaa
    79321 gaaaccttgc cagaaattgc ggatgaaatc aatattctca acttaactag taagccaaaa
    79381 aatcaaggat tacttgatcc ttatgtgatt atggagaaaa agaaggattc tgaaagtcta
    79441 gcaattgata ttctgacctt tttaacagga atttctagtc gagatgggga gaagtttcca
    79501 gtgttgcgta aggccattcg gacggttacc caaagcaatc aacggggatt attacaagta
    79561 attaatgagc ttcgaaaaga aggctcacca gttgcggaaa atatcgcgga tcacatcgag
    79621 tcctttaccg attatgattt tgcccatttg cttttctcag atggttcgat tacccagtcg
    79681 attagtttag ataggcagtt aaatatcatt caagtagcgg atttggtttt accagatgca
    79741 gaaaccactt ttgaagaata taccaccatg gaattgctta gtgtttccat gctaatcgtc
    79801 atttccactt ttgccttgga ctttatccat agtaatcgag aaatcttcaa aattgtagac
    79861 ttagatgagg cgtggagttt tcttcaagta gcgcaaggga aaacattatc gaataagctc
    79921 gttcgtgctg ggcgggctat gaatgccggg gtttactttg tcacgcaaaa tagtgatgat
    79981 ttactggatg aacgcttgaa gaataatatc gggttgaagt ttgcgtttcg cagtaccgat
    80041 attcatgaaa tcaagaaaac cttggaattc tttggcttgg atcgagaaga tgaaagcaat
    80101 caaaaacgcc tacgagattt ggaaaatggc caatgcttga tgcaggattt gtatggtcgg
    80161 gtaggcgtgg ttcaggtaca tccagtcttt gaagaactct tccatgcctt tgatacccgt
    80221 ccacctgttc aagagagaat ggagtgaggg gatgaaaaag aaactttttc ggattgtggg
    80281 aatcgttttt attagcatac tcactctgat agttctattg agtttagttg gtacggtagc
    80341 cgaggcgaca gggctagttg atgatacagt tgaagcagga aatctatatt ccaaatattc
    80401 actgaacaac tatcaactag atttctttgt ggatagctct tgggattggt tgccttggaa
    80461 ttggggtgat ggcttaggga aaagcgtgat gtatggtctt tatgccatta ctaatttcat
    80521 ttggacggtg agtttgtatt tgtcgaacgc cacgggttat gtggttcaag aggcttacaa
    80581 attagatttc atttcggata cggctgaaag tattggaaag aatatccaaa cattggctgg
    80641 tattactgaa aatggactcc agacctccgg attttatttt gggtttctat tattgatgat
    80701 tttagctctg ggggtgtatg tggcgtatac cggattatta aaacgagaaa ccacgaaagc
    80761 agttcgagcc gtgattaatt ttgtgatgat ttttctacta tcgggttcgt tcattgctta
    80821 tgcgcctacc tatatcacaa aaatcaatga ctttagctca gatgttagtg aagcggccct
    80881 tacccttgga accgagatcg ttgtacccaa ttcagaaagc caaggaaaag atagtgtgga
    80941 tttgattcgg gatagtttgt tttcgattca agtccaacaa ccttggttac tactgcaatt
    81001 tgatgattcc aacatagaag aaattggtga agaccgggtc aacaagattc tatctgtgag
    81061 tccagatgaa aacaaaggca aagatcggga agaagcggtc aaggcagaga ttgaagacaa
    81121 tgacaatgcg aatctcagta ttaccaagac catgaaccgt ttagggaccg tggtcttttt
    81181 ggtattgttc aatattggca tttccttctt tgtttttctt ctaacaggga ttatgttgtt
    81241 ctcgcaaatt ctcttcatta tctttgcgat gtttctgcca attagtttct tattgtccat
    81301 gttgccgact tatgaaagtt taggaaagaa ggcgattatt cgtttattca atacgattat
    81361 gatgcgagcg ggtgttactt tggtgattac gactgcattt agcatctcca cgatgttttt
    81421 caatatttcg gcaacctatc catttttcat ggttgctttt ctgcaaattg tgacctttgc
    81481 cggtatctat ttcaaattgg gcgacattat gagtatgttc aacctccaga gtaatgatag
    81541 ccagtcaatg ggaagacgcg tcatgcgaaa accgcaaatg ttaatgaatc gaaaattgcg
    81601 gcaactcaat cgaaatgtgg gacgagcttt ggcttttggt ggtggtgcag cagtcggaaa
    81661 taagttggca aaggaacaat caaaatccaa atttaagcca tccggttctt ctctacgaaa
    81721 gaattcacga ttaccgaacg atcacgaaat actatctgac ttaactaagg agaatccagt
    81781 ttcaaataat aagaaacaat cccgaatgaa tttggctggg agaaaaatcg gcaaagtttt
    81841 ggatacccaa gctttggtga aagataagac taaacaagta aaggatcagg taaggaatac
    81901 gccaacgaat ttgaaataca atctccataa aggaatcgaa aagtcgaaaa aagcaccaga
    81961 agaattcaag cgcggactgt tccaagaaaa agcggatcga gtggatttgc gagaaaaaca
    82021 acgacaacga agaaatgcga aaatggacga aaaacgcaag atactgagtg aagcaacaaa
    82081 tcgtcaggga aaaagaaggg cgaatattcc aatagataaa gcagctcaac ctcagaaaga
    82141 tatgatgctg aaaaaagaag caccaaagcg gattgtgaga gcaaatctga atcccgaaat
    82201 caaacgaaaa ctaactagtc aagaaatcat ttcaaaaggg aaaagccaat cagcaagtaa
    82261 gaaaaattct ttccaacaag tgaaacagag gtccactctg ccaaagcaga ccaatcaaaa
    82321 agtacaaaaa agaatgaacc atcgtccaaa atcaaggtca ggtgagaaaa aatgaacttg
    82381 aagaaagtgg gtgttatttc attaactttt ctgaccatct cttttatggg tattttgatg
    82441 tgtgtgggtt tgttgtttgg tgaagacagt gagggaaatg gtagttctgg cacttctcct
    82501 ggcggaacta gtgtctcaga agaagtattg aaacaccgtg caatggtgga aaagtatgcc
    82561 aaagaatcgg atataacaga gtatattcca attcttttgg cgattattca agtggaatct
    82621 ggtggcacaa tggaagacgt tatgcaaagt tctgagtcag ccggattacc acctaattca
    82681 ttaagtaccg aggcatccat caaacaaggc tgtctctatt ttgcgtcttt ggttaagcgt
    82741 tccaaagaac tagggtgtga tcaagatagt attattcagg cctataacta tggtggcggg
    82801 tatctagatc atgtcgggaa aaacgggaag aagcatagtt ttgctttagc tgaatctttt
    82861 tcaaaggaaa aatcaggtgg tcaaaaagtc gattacccca acccaatcgc gattaaggaa
    82921 aatggtgggt ggcggtataa ttatggcaat atgttttact gtttattagt gaagcaatac
    82981 ctaactacaa ctcagtttga tgacaaaata gtccaagaaa tttttgatga ggcatttaag
    83041 tatgaaggaa cggcctatgt gtttggtggc tcaagtccag aaacggggtt tgattgtagt
    83101 ggcttgaccc aatggtgtta tgccaaagtt gacctgaaac ttcctcgggt ggctcaggat
    83161 caatatgatg ccatgactca tattgatcta aaagatgcca aaccaggtga tttagttttc
    83221 tttcattcaa cctatgatgc cggtacttat gtgacccatg tgggcattta cgcaggggag
    83281 aatcgcatgt ttcatgcagg agatccagtg gggtggacga atctaacgga aaactattgg
    83341 cggcagcatc ttatcggagc tggccgatac aaataagaga aaagaggaaa aagaatgaag
    83401 ataaaaattg aacggaatca aaaggaaaag agcccaaaaa agaaaaaaga acgagttgta
    83461 tccgtgggta agcatcgaaa aatggtgctt gccctttggc ttttattgtc ttgtagtctt
    83521 gcttttggcg tttataaaaa tttcaccgcc attgatcaac atacaactca tgaaaaagtg
    83581 gttataaaag agaaggtagt gaatacttct ggcgttgaaa gttttacaga ggattttgcg
    83641 aaagaatatt tttcatggaa aaataacaaa gaagcaattg aaaagagaat gagtaatctc
    83701 gaacagtacc ttacagaaaa cggtctcgct ttaatccaag atatggttcg agcagatatt
    83761 cccacgagtt ccgaagttca atctgtaaaa attctagatg ttgaaaaaca ctcggaagaa
    83821 tttgtcgttt catttttagt ggagcaacat attacagagg gaaaaaagac gcaatcaatt
    83881 tcttctgcat atcgagtgac aatctttgaa gatgaaaaca ggaatcattt agtaactagt
    83941 ttgccaacaa tgattggaaa gccagacaag gcaaaatatg aagcaaaaca agtagaaaac
    84001 gattcagaaa ttgatgccaa aacaacggaa gaaatcaccg attttttaga aacatttttt
    84061 aaactttatc catcagcttc tgaaaaagaa ttggagtatt atgttgaaaa tggtgcgatg
    84121 cgaccaatca atattgactt aaagttttcg gagttagaga atccagttta tctacaaaac
    84181 ggaaaaaatt ttctagtgag tacaaagata aaataccttg ataatgtatc aaaaaccact
    84241 agctactttc agtacaaatt agtattacaa aaaaatggaa actggaaaat cgttgatgtt
    84301 aaataataat gactcaatct aattttatta gaagttataa gtagtgtaac ttatttcagg
    84361 cagaagtcgc ccatcctcta taggtgggtg atgaatgcca ttcggtaact cgaaaaccga
    84421 caattaagac atagtgcctt tttattttaa tccatgtcat aatcagtcta tataggaaat
    84481 ggttgatata ccatggaatt agatacaaat aatcattcag tttttcttct tggttacccc
    84541 cttattttag tagtgaaaca ttgtaaacat gtcattgatg atgtaatgtc agcttatgca
    84601 aaaactgcct ttgaaagaat ttcagaatca catcacatta ccttagatga atgaaatcgt
    84661 gataaagaat actttcatat tatgctcaaa gcacaaccta aaaccgaatt aacaaaattc
    84721 agcaatgcct aagctcacgt ctgataaaat gagactttct aagggtcaaa aatttccttt
    84781 gaatacgatt attgcttaga taaaagtaaa agccttagaa ctacggggat agcttggtta
    84841 ataagagata tcgttgttag taaagacata ggcttgcaag tatgctctat tcccaagaat
    84901 ctcccccttc aagcaccaag gatcgttaaa ttcagctaag tggcaagtaa ttcactagac
    84961 gataattatc tccatatttc aatctcagct tttccatttt tcatagcaaa ttccgttatt
    85021 tttatagcat ctaaaagatt cagcttttcc actgatcttt caccactttt cagctttttt
    85081 attgtgctta aattgatacc agtacctttt gatattgaat tggaagtaaa atcattaagg
    85141 gtttttttta ttaaattcat atccgcaatt ccagcgttca taagaatgaa gattctcctc
    85201 tcatagacta ctttgaaaat ggtactacag tggctgttta tatatttcag taggttactg
    85261 tagtggtcat cttattataa ttagaaaagg aacctaaatc aaaaatgcta aagaaaattt
    85321 tcatagtatt aagcctctca tgactaaagc cacggaattc ttgataaaag agtatacttg
    85381 caagcctaaa cagcggtatc tcttattaac caagctatcc ccgttgttcc taaggttctt
    85441 gatgttttct aaggcaatgc ttgtattcat agcccttggt caaaatattg atactatcgt
    85501 tgacgtttcg attatgatgt atacggcaaa taggacaagt ccattctcga attgtgagtg
    85561 acttcttacc atctgtgtgt ctacattctg aaccaatttg actagacgga aatcatttat
    85621 ctatcttaat gattttttga cagaagtatc gaaaatcttt acataatctg ggtgatgtat
    85681 tcttatgcag atgagagcgt tggctccgta ttcataacca gtagcctcta aaacgtagtc
    85741 catcggtggg atacctagct tgcggttgcc agcggctttc gcagtcttct tgtgatcaaa
    85801 tcaagcatct cattgagcac tagtattttg aagataatac ttgagttttt cggcttttag
    85861 aagttcactt catcttccat catccatgga aatcccactc acccatacgc aggcctccaa
    85921 aaattcttca acagtggttt tttcagacat ttttctgaat acctccttgt tttttgatac
    85981 gccagatagt caggaaaaag gcaacaaaac acaaaacaaa gctgcctaaa aaggtaatct
    86041 tcattccata taaaaagaca tccggccgat ttgcgatata gttagttact tgctggccca
    86101 tcttagcaga catcgcttga tataagaccg tcgtagaaag cgaaatcccg ctgaccatcc
    86161 ccaaatttcg ggcaaaggaa ttcatcgagc ctgccagtcc caagttttcg atagtgaccg
    86221 agctcataac catcgtatta ttgggggact ggaacaaggc attgccggca cccatgatgg
    86281 cagtagcgac aatgtatagc cacaaaggag agtccactga caaaaacata tacatgacct
    86341 gggttaccga caataagccc aagcctacta ataccaaaat ctccgggcca acccggtcgg
    86401 tcaggtagcc gcttaaaggc gccccgacga ccatcatcaa aggaaagacc atcatcaaca
    86461 gcccagcata gctaggactc aacccgcgag cattttgcag ataaaaagga atcactacat
    86521 tgacaaagaa gttggaagaa aaaatcaaca aggctgtaat caagctcatg gtaaaaatct
    86581 tgttcttaaa aataccgaaa gaaatcaatg gagaggctgc tttcttttca acttttaaaa
    86641 agctgacaaa ggcaatcact gaaattacga acagtacaag ggggactgga tggaaaaagc
    86701 cactttcttg ccccaaaaag attgctccaa aaaagctgat aatcgtagcc gcaatggcag
    86761 caaagccccc tccatcgatt gtatggccgc tcatggtgat atcttttggt aagaattttt
    86821 cagcaatcaa catcgttacg attcccaccg gtacattgat ccaaaaaatg tacgcccaag
    86881 aaaattggga caaaatcaag ccgccaagac ctggtccagc aatcgagcct aatgaaacaa
    86941 acgcacctat tgctcccaat gcccgaccac gttcatgtat gggaaagact tccgtgatga
    87001 ttccggcatt tgtagccata gtcatactag caccaatggc ttgtaccacc cgtgcgaaca
    87061 ataaaatacc tagcgaatga ttgaacccac acaacagcga tcccaagaca aagatcagcg
    87121 taccaatccg aaatactttg attttcccac ggctatcgcc aattttacca aacagcaaca
    87181 aacaagaaca gacaatcatc agataaacgg acactaccca ttccgcttga ttcattggta
    87241 tgcccatatc atctgagatg gtaggtagtg caatattgac aatactgcca tccaatgtgg
    87301 acatgaaggt aaacatagat atagcaatca aaatccacca gcgatttttt tggacttttg
    87361 catcttcttg ataactatac ataataggat ttcctttcta atgatcgtgt agctaagaac
    87421 aatataacct atgtctactg cccaacaact tctcgcgact ctagccatag gaagcttgag
    87481 taatttcgat ttgatatcct catgtaacca tgtaagttgg agatgcttta tttgaactta
    87541 ctctatagta actagtgata attcgcttta ctttcttcta gcaatttcta aaagtcgact
    87601 tcattgttct tcagattaat agtgtgagct atctcgtgag acgtaagcaa atttccattc
    87661 tactttttcc caattttttc atatttatgg tgttgcacct atttgttttc caatttgctt
    87721 ttcaaataca ttgctatgat attcaattcc ataggattat act
//
LOCUS       DAZKCW010000004        81585 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000004 DAZKCW010000000
VERSION     DAZKCW010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 81585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.004"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..936)
                     /locus_tag="ACG84Z_000260"
     CDS             complement(<1..936)
                     /locus_tag="ACG84Z_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9161136.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRE"
     gene            complement(1065..1829)
                     /locus_tag="ACG84Z_000261"
     CDS             complement(1065..1829)
                     /locus_tag="ACG84Z_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFP9161137.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(1833..2222)
                     /locus_tag="ACG84Z_000262"
     CDS             complement(1833..2222)
                     /locus_tag="ACG84Z_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161138.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            2357..2899
                     /locus_tag="ACG84Z_000263"
     CDS             2357..2899
                     /locus_tag="ACG84Z_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFP9161139.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            3047..3679
                     /locus_tag="ACG84Z_000264"
     CDS             3047..3679
                     /locus_tag="ACG84Z_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161140.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITVAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(3813..3938)
                     /locus_tag="ACG84Z_000265"
     CDS             complement(3813..3938)
                     /locus_tag="ACG84Z_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFP9161141.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(4072..4965)
                     /locus_tag="ACG84Z_000266"
     CDS             complement(4072..4965)
                     /locus_tag="ACG84Z_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFP9161142.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(5147..6073)
                     /locus_tag="ACG84Z_000267"
     CDS             complement(5147..6073)
                     /locus_tag="ACG84Z_000267"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFP9161143.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(6158..6919)
                     /gene="pflA"
                     /locus_tag="ACG84Z_000268"
     CDS             complement(6158..6919)
                     /gene="pflA"
                     /locus_tag="ACG84Z_000268"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFP9161144.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(7163..9394)
                     /gene="pflB"
                     /locus_tag="ACG84Z_000269"
     CDS             complement(7163..9394)
                     /gene="pflB"
                     /locus_tag="ACG84Z_000269"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFP9161145.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(9671..12121)
                     /gene="parC"
                     /locus_tag="ACG84Z_000270"
     CDS             complement(9671..12121)
                     /gene="parC"
                     /locus_tag="ACG84Z_000270"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFP9161146.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(12133..14178)
                     /gene="parE"
                     /locus_tag="ACG84Z_000271"
     CDS             complement(12133..14178)
                     /gene="parE"
                     /locus_tag="ACG84Z_000271"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFP9161147.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(14344..14778)
                     /locus_tag="ACG84Z_000272"
     CDS             complement(14344..14778)
                     /locus_tag="ACG84Z_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFP9161148.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            14905..15543
                     /gene="plsY"
                     /locus_tag="ACG84Z_000273"
     CDS             14905..15543
                     /gene="plsY"
                     /locus_tag="ACG84Z_000273"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFP9161149.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(15675..16550)
                     /locus_tag="ACG84Z_000274"
     CDS             complement(15675..16550)
                     /locus_tag="ACG84Z_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFP9161150.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVIRYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(16632..17423)
                     /gene="codY"
                     /locus_tag="ACG84Z_000275"
     CDS             complement(16632..17423)
                     /gene="codY"
                     /locus_tag="ACG84Z_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFP9161151.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(17441..18841)
                     /gene="hslU"
                     /locus_tag="ACG84Z_000276"
     CDS             complement(17441..18841)
                     /gene="hslU"
                     /locus_tag="ACG84Z_000276"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFP9161152.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(18855..19403)
                     /gene="hslV"
                     /locus_tag="ACG84Z_000277"
     CDS             complement(18855..19403)
                     /gene="hslV"
                     /locus_tag="ACG84Z_000277"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFP9161153.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(19440..20345)
                     /gene="xerC"
                     /locus_tag="ACG84Z_000278"
     CDS             complement(19440..20345)
                     /gene="xerC"
                     /locus_tag="ACG84Z_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFP9161154.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(20543..21919)
                     /gene="trmFO"
                     /locus_tag="ACG84Z_000279"
     CDS             complement(20543..21919)
                     /gene="trmFO"
                     /locus_tag="ACG84Z_000279"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFP9161155.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(21888..23966)
                     /gene="topA"
                     /locus_tag="ACG84Z_000280"
     CDS             complement(21888..23966)
                     /gene="topA"
                     /locus_tag="ACG84Z_000280"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFP9161156.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(24088..24945)
                     /gene="dprA"
                     /locus_tag="ACG84Z_000281"
     CDS             complement(24088..24945)
                     /gene="dprA"
                     /locus_tag="ACG84Z_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFP9161157.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(25001..25768)
                     /locus_tag="ACG84Z_000282"
     CDS             complement(25001..25768)
                     /locus_tag="ACG84Z_000282"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFP9161158.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(25761..26621)
                     /gene="ylqF"
                     /locus_tag="ACG84Z_000283"
     CDS             complement(25761..26621)
                     /gene="ylqF"
                     /locus_tag="ACG84Z_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFP9161159.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            26882..27280
                     /locus_tag="ACG84Z_000284"
     CDS             26882..27280
                     /locus_tag="ACG84Z_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9161160.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWVMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            27517..28059
                     /locus_tag="ACG84Z_000285"
     CDS             27517..28059
                     /locus_tag="ACG84Z_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFP9161161.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRVIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(28142..28693)
                     /gene="lepB"
                     /locus_tag="ACG84Z_000286"
     CDS             complement(28142..28693)
                     /gene="lepB"
                     /locus_tag="ACG84Z_000286"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFP9161162.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(28845..29072)
                     /locus_tag="ACG84Z_000287"
     CDS             complement(28845..29072)
                     /locus_tag="ACG84Z_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFP9161163.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(29069..29587)
                     /gene="msrA"
                     /locus_tag="ACG84Z_000288"
     CDS             complement(29069..29587)
                     /gene="msrA"
                     /locus_tag="ACG84Z_000288"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFP9161164.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(29607..30320)
                     /locus_tag="ACG84Z_000289"
     CDS             complement(29607..30320)
                     /locus_tag="ACG84Z_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFP9161165.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(30323..31219)
                     /locus_tag="ACG84Z_000290"
     CDS             complement(30323..31219)
                     /locus_tag="ACG84Z_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFP9161166.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(31377..32219)
                     /locus_tag="ACG84Z_000291"
     CDS             complement(31377..32219)
                     /locus_tag="ACG84Z_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFP9161167.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEEILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            32351..33004
                     /locus_tag="ACG84Z_000292"
     CDS             32351..33004
                     /locus_tag="ACG84Z_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFP9161168.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(33068..33595)
                     /locus_tag="ACG84Z_000293"
     CDS             complement(33068..33595)
                     /locus_tag="ACG84Z_000293"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFP9161169.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEIDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(33615..34562)
                     /locus_tag="ACG84Z_000294"
     CDS             complement(33615..34562)
                     /locus_tag="ACG84Z_000294"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFP9161170.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKEVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(34574..36457)
                     /locus_tag="ACG84Z_000295"
     CDS             complement(34574..36457)
                     /locus_tag="ACG84Z_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFP9161171.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSGDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            complement(36625..38697)
                     /locus_tag="ACG84Z_000296"
     CDS             complement(36625..38697)
                     /locus_tag="ACG84Z_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFP9161172.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRHADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKRVQ"
     gene            complement(38710..38985)
                     /locus_tag="ACG84Z_000297"
     CDS             complement(38710..38985)
                     /locus_tag="ACG84Z_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161173.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(39347..39802)
                     /locus_tag="ACG84Z_000298"
     CDS             complement(39347..39802)
                     /locus_tag="ACG84Z_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161174.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(39956..41164)
                     /locus_tag="ACG84Z_000299"
     CDS             complement(39956..41164)
                     /locus_tag="ACG84Z_000299"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFP9161175.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPSLKEEGEALLRFAELPSVPLKEESQVWTLLISQLGLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(41276..41608)
                     /locus_tag="ACG84Z_000300"
     CDS             complement(41276..41608)
                     /locus_tag="ACG84Z_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFP9161176.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            41756..42631
                     /locus_tag="ACG84Z_000301"
     CDS             41756..42631
                     /locus_tag="ACG84Z_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9161177.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(42713..43294)
                     /locus_tag="ACG84Z_000302"
     CDS             complement(42713..43294)
                     /locus_tag="ACG84Z_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFP9161178.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(43300..44559)
                     /locus_tag="ACG84Z_000303"
     CDS             complement(43300..44559)
                     /locus_tag="ACG84Z_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFP9161179.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIAPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(44561..45607)
                     /locus_tag="ACG84Z_000304"
     CDS             complement(44561..45607)
                     /locus_tag="ACG84Z_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161180.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQRPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(45842..46117)
                     /locus_tag="ACG84Z_000305"
     CDS             complement(45842..46117)
                     /locus_tag="ACG84Z_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFP9161181.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(46360..47670)
                     /gene="der"
                     /locus_tag="ACG84Z_000306"
     CDS             complement(46360..47670)
                     /gene="der"
                     /locus_tag="ACG84Z_000306"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFP9161182.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(47852..49081)
                     /gene="rpsA"
                     /locus_tag="ACG84Z_000307"
     CDS             complement(47852..49081)
                     /gene="rpsA"
                     /locus_tag="ACG84Z_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFP9161183.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(49216..49896)
                     /gene="cmk"
                     /locus_tag="ACG84Z_000308"
     CDS             complement(49216..49896)
                     /gene="cmk"
                     /locus_tag="ACG84Z_000308"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFP9161184.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAIQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(49944..50579)
                     /locus_tag="ACG84Z_000309"
     CDS             complement(49944..50579)
                     /locus_tag="ACG84Z_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFP9161185.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(50645..52048)
                     /locus_tag="ACG84Z_000310"
     CDS             complement(50645..52048)
                     /locus_tag="ACG84Z_000310"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFP9161186.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGFLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVIHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKHQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(52035..53066)
                     /locus_tag="ACG84Z_000311"
     CDS             complement(52035..53066)
                     /locus_tag="ACG84Z_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9161187.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYERILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            53097..53318
                     /locus_tag="ACG84Z_000312"
     CDS             53097..53318
                     /locus_tag="ACG84Z_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFP9161188.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(53483..54220)
                     /locus_tag="ACG84Z_000313"
     CDS             complement(53483..54220)
                     /locus_tag="ACG84Z_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9161189.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGNSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(54374..55714)
                     /locus_tag="ACG84Z_000314"
     CDS             complement(54374..55714)
                     /locus_tag="ACG84Z_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFP9161190.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(55951..57474)
                     /locus_tag="ACG84Z_000315"
     CDS             complement(55951..57474)
                     /locus_tag="ACG84Z_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFP9161191.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(57852..58463)
                     /locus_tag="ACG84Z_000316"
     CDS             complement(57852..58463)
                     /locus_tag="ACG84Z_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFP9161192.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIP
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(58586..58710)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(58792..59508)
                     /locus_tag="ACG84Z_000317"
     CDS             complement(58792..59508)
                     /locus_tag="ACG84Z_000317"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFP9161193.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(59514..60083)
                     /gene="scpB"
                     /locus_tag="ACG84Z_000318"
     CDS             complement(59514..60083)
                     /gene="scpB"
                     /locus_tag="ACG84Z_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFP9161194.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISFEEDVSPDLFFDGMNKGE"
     gene            complement(60067..60837)
                     /locus_tag="ACG84Z_000319"
     CDS             complement(60067..60837)
                     /locus_tag="ACG84Z_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFP9161195.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(60834..61205)
                     /locus_tag="ACG84Z_000320"
     CDS             complement(60834..61205)
                     /locus_tag="ACG84Z_000320"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9161196.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGVYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(61224..62111)
                     /gene="xerD"
                     /locus_tag="ACG84Z_000321"
     CDS             complement(61224..62111)
                     /gene="xerD"
                     /locus_tag="ACG84Z_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFP9161197.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(62207..62680)
                     /locus_tag="ACG84Z_000322"
     CDS             complement(62207..62680)
                     /locus_tag="ACG84Z_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFP9161198.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(62785..63648)
                     /locus_tag="ACG84Z_000323"
     CDS             complement(62785..63648)
                     /locus_tag="ACG84Z_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFP9161199.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(63844..65985)
                     /locus_tag="ACG84Z_000324"
     CDS             complement(63844..65985)
                     /locus_tag="ACG84Z_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFP9161200.1"
                     /translation="MMKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDA
                     AMQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIE
                     KNEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHRED
                     TKEEHAKELLKMISEKIAQENKVEPEHEAEKDTEKDISGVNAAGKESLKTNDLKTNDL
                     KTDIPEKTETLSEKQSEDEKSNGLPEADKKEMLEKADKKATESDGINNEADAETQSAS
                     EDSTALEAKIEKEENQPELIEAETEPITIVPNTEKTPQESNPEKKDLDKTQKKKSKKV
                     PYLALAAVLLLGGGGWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFI
                     RADMIHQDLSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDH
                     LADDIKLKADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVV
                     DSATRDQYKTAKEAVEKVKNTDLSAQLNEQLQQVDKMLTDKEKKEEEEKKKAEEAKKA
                     EKAKKAAEEQAKQAAQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARAS
                     DIADASNPAWTWAPGVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKS
                     ALMKGIGESALPFYIVTINCKTGWFGGNGSN"
     gene            complement(66202..67311)
                     /gene="rpoD"
                     /locus_tag="ACG84Z_000325"
     CDS             complement(66202..67311)
                     /gene="rpoD"
                     /locus_tag="ACG84Z_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFP9161201.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(67335..69176)
                     /gene="dnaG"
                     /locus_tag="ACG84Z_000326"
     CDS             complement(67335..69176)
                     /gene="dnaG"
                     /locus_tag="ACG84Z_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFP9161202.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(69358..71673)
                     /locus_tag="ACG84Z_000327"
     CDS             complement(69358..71673)
                     /locus_tag="ACG84Z_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFP9161203.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(71858..72718)
                     /locus_tag="ACG84Z_000328"
     CDS             complement(71858..72718)
                     /locus_tag="ACG84Z_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFP9161204.1"
                     /translation="MEKRQKMENQKVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(72777..73409)
                     /locus_tag="ACG84Z_000329"
     CDS             complement(72777..73409)
                     /locus_tag="ACG84Z_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFP9161205.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            73576..74337
                     /locus_tag="ACG84Z_000330"
     CDS             73576..74337
                     /locus_tag="ACG84Z_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9161206.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            74363..76954
                     /gene="mprF"
                     /locus_tag="ACG84Z_000331"
     CDS             74363..76954
                     /gene="mprF"
                     /locus_tag="ACG84Z_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFP9161207.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(77142..78329)
                     /gene="tuf"
                     /locus_tag="ACG84Z_000332"
     CDS             complement(77142..78329)
                     /gene="tuf"
                     /locus_tag="ACG84Z_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFP9161208.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            78697..79053
                     /locus_tag="ACG84Z_000333"
     CDS             78697..79053
                     /locus_tag="ACG84Z_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFP9161209.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(79294..80298)
                     /locus_tag="ACG84Z_000334"
     CDS             complement(79294..80298)
                     /locus_tag="ACG84Z_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFP9161210.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            80464..81315
                     /locus_tag="ACG84Z_000335"
     CDS             80464..81315
                     /locus_tag="ACG84Z_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFP9161211.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            81332..81577
                     /locus_tag="ACG84Z_000336"
     CDS             81332..81577
                     /locus_tag="ACG84Z_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161212.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
BASE COUNT        22449 a        17151 c        14006 g        27979 t
ORIGIN      
        1 ctctctgata actagttcag gaaaaaaacg acgataacct tgactcgccc ctttttcttc
       61 tatttttttt aacaacattt ctccacatac ttcacccata cgtataatat cttgcttgat
      121 cgttgtcaat ttaggtgaac tgatttggtc taaaaatacc ccatcaaatc caatcacacc
      181 aaattcttcg ggcaagtgtc ctccagcatt tataatccct cttactgctc ctagtgctag
      241 ccgatctgaa ctacatacaa aacaagtttt atctgtaaaa tctgcccagt tttctgtcat
      301 atatctttct acttctgtcg aatgatttgg aaaccgcaag attttactag gaagatcaac
      361 ttccttcatc acagataaat aaccagtttc ccttgaaatt tcaaaaggct cgtccacttc
      421 gataccgata taaataatcg tttgataatc tctttctaag gcatattgcg ttgcttttgc
      481 tgtaccatat tcattatcgc tgtctacata atcatatcct tcagaatttt ccccaaacaa
      541 gacaactggt ttttccaaac ggtcgatcca atcgaagtct ttttttctga cacctgtgat
      601 gatgtatcca tcacaagaac cgacgtcgaa ggcatcattt gtaactaatt ggagagaata
      661 atgcgcttta ccgatccgtt tagcgattcc catcagcaaa ttcatgtaat agggctcagt
      721 tgtgtcgatt tcttccagta taaataattt gatgatctgc gaccgattcg tgacaagtgc
      781 ttttgcagca atatttggac ggtaatccag ttcagccatt gctgagaaaa ctaactcttt
      841 caattcgtca gtcacctgtt ccggatgatt gatgactcga gagaccgtca tttttgaaac
      901 attggcacgt tttgcaacat ctgctaaagt gggcatgctc tcttcctttc taacatgttg
      961 tcattcttac tatcaattat accaaatttt cctaacagag tttattatag cccaaaataa
     1021 aaaacggaaa atcctctatc gtcatgagtg attttccgtt tcaattattt atactttttt
     1081 atcaaatttt ttgctaaaaa agtggaagct tcttccatta gtggtatttg taccatatgt
     1141 cgctgtgttt ttgaggaacg aaaaacaatt tcttttccgt aagacttatg ccgatttttt
     1201 tctacaaatc gttccgtttg tatataaggg attttttcgt cagcttgtcc atgccaaaag
     1261 aacagaggac gtccagctaa cttttccggc tgcaatgaca aatcatagct cttaacccat
     1321 gaaatcaaat caaaatagtc ttttggtacg acataattat attccgatgc gcgccttacg
     1381 atttcttttc catattccaa aggtgcaggg gaacccatca aacacacgcc cgctactata
     1441 tgaggatgtt tagccaacaa ggcgcatgtt gtcattcccc ccatcgaaac cccgccaact
     1501 gcaagctgat catgtagaag acctcttttt tctaaatgct tgataagtgt gtcaaattca
     1561 aacagatttc cgtagatact atcccaaaat gtataggatg gaatagaaga aaccggctgt
     1621 ttgcgctccc catgattcat cgcatctggc aggatcacac gaatgccctg ctgcgcaatt
     1681 tttcttcctt gcgtcaaaac taactcctta cttgtctgcc atccgtgata atagatgaca
     1741 acgggaatac gttcctctct taattctttc agaacaactt ctaacactgg aatatgatgg
     1801 acagaacgtt tcaatataat tggattcaat tgttactcac ctattttcat taaatttcct
     1861 gatcgccata gcaaccatgc tccaacagtt gtctggaaca ggttcagtgt accaaataat
     1921 ataaatgcag gactgaatgg ctcgggaaat aagcacagag aacaaagtcc caccactcct
     1981 aatgctagcg aaaggagtgg ataaatagaa aaattcaaaa aactggcaac gctaccgaaa
     2041 atattaccaa taaacagtat caaaaagaaa aaaacgctta aaattaaacc atctgtcagc
     2101 gacatctgaa aaacaatgtt ctctacctca attggctgtt gaatcgaata gacacctaag
     2161 tatatactga gaaggagact tagcacgtgg ctggcacaaa acacacgatt gaccgttttc
     2221 attttaatca cctaacctat ctttataatt ctattataat cattttatca tttttttgta
     2281 tgtataaagt ttcaattttt cttcacttac gatttttttt gatattgttg ttatataaat
     2341 gaaaggagtt ttacaaatga ttgatccaaa aatgttgggg atgatcttcc tcattaattt
     2401 tgcttatatc actctgaaca cgttacgttt catgttgaca atgaaaggct atcgactgat
     2461 tgctccactt gtcagtatgg tcgagatcac gatttatatc gtcggcttat cccttgtttt
     2521 agatcgttta gataatccac tgaatttatt tgtctatgcg ttaggttacg cagtaggtat
     2581 cagtgtcgga attttgattg aagacaaatt ggcattagga tacatcatgg tcacaacgat
     2641 tttgccagca aatagcgcag aagataaaag tttgccgggt atactgagag aacacggtta
     2701 tggtgtgaca cagacttctg caatggggct ggaaggtgag cggctagttc tcgaaatact
     2761 ttctcctaga aaaagcgaac gtgaactgta tcgcctgatc aaagaaatcg aagagcgtgc
     2821 ttttatcatt tcttatgagc caaaatatat ttcaggtggt ttctggacta aaaaagtgag
     2881 aaaacgacaa ggaaaataac tcacaaactt aaaaactgtc taatatctaa attaaatttt
     2941 aaatgttaga cagtttttat ttattatttt gattaaaaaa catcgacata tactcatcaa
     3001 tttgttatta tactttatat acttatcaat ttaatttgga gatattatgg aaattcaacg
     3061 tagaaccact aattttttac atttaggctc tttttttgca actttgacga tcttattttt
     3121 tctatgttat tcatacctta agacctcaca tgcgccttct agtgcattag gctggttgct
     3181 tttggatcat tctgatatca cagtagccga agaaaatccg ttttttttga ttttgtcttc
     3241 tctttgcggc ttactgtttt ctgtttattt cggtgcctat ttttttcatc gacatcctgg
     3301 tacgttaaac gaagcttcaa gcgtattgat tgcatttaaa acgttttctt ttttagcaat
     3361 tcttttttat tcgtttaatc acaatacgct tttcttcttt atcatgaatg gtttagtcgt
     3421 gattttatcc atttttactt attttatttt ttcactcatt tttagccaat tgaaatgtcc
     3481 gctcttcttt cgattagttc ctgtcacctg ttttatttac agcttgtttt ccttttttgt
     3541 ccttgcttta atgccactga ccaacccttc gacgatccaa gtcgcaggaa atctgttgga
     3601 tatgctcttc atcgtcagtc taggtgtatt tatgtggcaa agaaaaaaca aacaaaataa
     3661 aaagcatttt gaagcctgac tattacgact tcataaatgc ttttttagtt ttaaacactt
     3721 caatctaaaa gaataaccca agattggata aattattaat gactcgccat tcgtttctta
     3781 gtgattctgg attatcaaat ggacttccta atctaatcag ctagttcttc ccataaaatg
     3841 ccatacttga ctgaatcata atattgatta tttaaaaatc taacttttct tatcactact
     3901 tcctttgtca ttccacattt ctcaccattt ttttgcattc ctttgtttcc agaccatgta
     3961 gtgaatctaa taggtggtag ataggcaaaa tactcaaata attcttttaa ccataaagga
     4021 agagaaaggc tcctcctgca agagtcagta taatttttgc ttactgctct cttaggtttt
     4081 actcactaaa actgttccat attctttgat ataagaaaat gcatgcggta taaatttctt
     4141 gctcagctca gaaaagattt gtcgtttaag aaaggccatt tcctccattg tcaatgaagg
     4201 atccaatgtt ggtaattcaa tctcaaaatt gtttttttcg acaataggta attctaatgt
     4261 gaatgattct tcttccttta tagtattcgt cacaagtaga gactgatgga aaatactagg
     4321 ccggcgattt ttatatttat tcttacgtat cctgtcaacg ataacttcta tttgatcaaa
     4381 aaagtacgat tcatttacgt ctccaataag ttcggctaat tctttgaatg ccttcgttac
     4441 aggaagctga ttcttctgta caaaaaagta attagccaaa gtaagcggga agtgttctat
     4501 agaggaaagt gtgataaaac ggtacttctc atttcctgca gttgtcctca gcaattctgt
     4561 ctctcggctg tttcttactc cataaaaata cgcttctttc cgttcatctt cgaaacaata
     4621 cgcccaaata acttctccca tcgctaattt ttgttcatca acagagagtc tcttcaattg
     4681 ttcagctatg gtttcagcag ccgaagtggc ttgttgcaag taatctttag gatcaaatat
     4741 tggaaagttc aaatgatatc ttcgttcttc cctcttgatt aatcctgcat cgatcaataa
     4801 atcaagaaaa tgggaaaatt tattttgcga aaattctttt ttcaattctc ttagaatcgt
     4861 ttcttgttct cgatgttcat atagataatc ggtcaatgaa gaaaaaagcg gatcatcggt
     4921 cagtttttga taaaagtttt ccttattttt tgaataatag ttcatatatg ttctcttttc
     4981 tatccgtttt attttactta aaaggctttt acgtaaaaag gaggaagaac aagagtcata
     5041 attgactgtt attctcctcc atttcttcgg cctttagtat gttctatgtt tctttttata
     5101 tcaatcgctt atccattcat tttgaatgct tcatactacc atttgattag ctaaatacag
     5161 ccgtcaattg aggtacgact tgttttttac gtgaaacgac acctttaagc aaagcacggt
     5221 tgttggtcaa agttgtttgg aaagcttctt ctactttttc ttttccttta ccagcaacaa
     5281 gtaattctga atcactgtct aagatgtttg tgacaactaa tacgaacaga tcgtagccat
     5341 ttgctttcat ttcatcttcc attgctgctt ctagctctgc ttgtcgatcc atcacttcat
     5401 taaggtccac tgtattgact tgagcgatac gaacgttgga actgcccatt gggaaacttt
     5461 ttgcatccaa atcaagaaga accgcagctg atttatcact tagatttgtt cctgctttca
     5521 acatttcaag tccataagtg tttagatcga cttcagcgat tgctgcaagt tcttttgcag
     5581 ctgcttcatc ttcaggcgta catgttggtg atttgaacaa caatgtatct gaaatgatag
     5641 ctgagagcat gattcctgcg atttctttag gaattgttac ttggttttct ttatatagtt
     5701 ttaaaataat cgtacttgta catccaactg gttctgcacg atagtacaat ggattagctg
     5761 tttcaaagtt tgcaatacga tggtggtcta ctacagctaa aatatttact tcgctgatat
     5821 ctgaaatact ttgttggaat tcattatgat ccacaagcat gacatctgca ttttctgctt
     5881 tagctgactc tactactcgt ggtgcagata gctgaaagtg gtctaatgcg tattgtgttt
     5941 cttcattagg tgtacctaga gcaactgctt ctgtttcttt acctaattca ttttgcaagt
     6001 gtgaaaacgc aatggctgcc ccgattgcat ctgtatctgg attttggtga ccaaaaacta
     6061 aaatttttga catgtcattc gctcctttgt gatttctcct atttaataat agcaaaaaaa
     6121 cggaaagaag caatacttat cttctttccg atgcgaccta tcgcgttaaa tattttgtat
     6181 actcttctgt atgaagcaat cgtttagcat tttcgacacg ttcttttgta ggtggttcga
     6241 tcccttctaa tggatatttc aaaccaagtg tttcccactt gtattttccc atcgtatgat
     6301 aaggaagaat ctctactctg tctacatttg acaaggtttg aataaagttg tctagtcgga
     6361 tcaaatattc atcataatca cttcgctcag gaactagtac atggcgaatc caaaccggtt
     6421 tgttgatttt tgacaaatat tgagccattt ctaaaatatt ttcattgtcc caatgcgtta
     6481 gttttttatg ctcttcatta tcgatgtgtt tgatgtcaaa taacagtaaa tctgtatact
     6541 tcatcaattc ttgaaaacgt gaaaagaaag gttcttcata cgtaaaaggt tttccgcatg
     6601 tatccaatgt agtatgcatc ttccgctctt ttgctttttt aaatagttcg atcaaaaaat
     6661 cgatctgcaa tagaggttct ccaccactaa cagtaatacc acctttatct ccccagtaag
     6721 gtctgaagcg ttctgcttta tctaaaagtt catctgctgt gtattctttc cctccgccaa
     6781 tattccaagt atctggattg tgacaaaatt ggcaacgcat gcggcatcct tgcataaaca
     6841 cgacaaagcg cagtccaggt ccgtctactg aaccgaaagt ttcgatagaa tgaacatagc
     6901 cgattgtttt ttcttccatt taagttcaca tcttttcttt gatttcattt taagtacaag
     6961 ttagctgtcg aagcgaagct ttctgaacaa aatttttcgc aattgccgct tcgttatgtg
     7021 taaaatttac agggacggaa catacaagtc ctgcccctgt aaatcgtttc tttcaaataa
     7081 gcatactgat tattcgattt tgatgcgatg gctattcaac gtcctttcga cgctaagtcg
     7141 aaaaactttt ttcacgaact ttttacattc tgtcgtgtga agttctcatc aagacatcta
     7201 attgttgttc tcttgtcaag tcacggaatt taactgcata accagatacc cggatcgtca
     7261 agttcggata tttcattgga ttttccattg catcacgcaa taaatcatta ctgaatacat
     7321 tgacattcaa atgataagct ccttttgaga agtatccatc taagacatta cgcaagtttt
     7381 cgattcttgt atcttgttct tttccaagac ctgaaggatt gattgtttgg gtatttgaaa
     7441 ttccatccaa tgcacagccg taattcattt tagctgttga gttcaggcta gctaataacc
     7501 cactttgttc cgcattgtaa cttggatttg ctcctggcgc aagtggtttt ccagcttcac
     7561 ggccatcagg agtatttcct gtatttttac cgtaaacaac atttgaagta atcgtcaata
     7621 atgaagttgt tggttttgag ttgcggtaag ttttatgacg tttgatttgt cccatgaagt
     7681 attccaagat ccatgaaact aattcatctg cacggtcatc atcatttccg tatttaggga
     7741 agtcgccatc cacttcaaaa tcaactgcta ttcctttttc attacggatt gcttttactt
     7801 ttgcatattt gatcgctgac aagctgtctg ccgcatgaga gatcccagca atacctgtag
     7861 caaatgtgcg ttgcaagtca gaatccatca aagccagctg agctgcttca taagaatatt
     7921 tatcatgcat ataatgaatg atgttcaacg tattgacata tagttctgct aaccaatcca
     7981 tcatattcat gaagttatgt ttcacttctt caaagtctag tatttctgat gtgattggac
     8041 gatattctgg tccaacttgg gcgccagtca cttcatcgac tccgccattg atggcatata
     8101 atagtgtttt agccaagtta gcacgagcgc caaagaattg catgtctttt ccgacaactg
     8161 ttcctgatac acagcaagca atcgcacaat catcagaacc ccattgttca cgaagctgat
     8221 tatcattttc gaattgaatc gaagaacttt cgatagcgat tctgctagca tatgttctga
     8281 atccttctgg aaggtgttca gaatacaaaa cagtcaagtt tggttctggt gaaggtccca
     8341 tatttgttaa tgtatgaagc agacggaaat cattctttgt aactaatgaa cgaccatcta
     8401 atcccatacc tgcaatggat aaagtagccc agatagggaa tcctgagaat aattggttat
     8461 attcaggtgt acgcgcgaat ttgaccatac gtaatttcat tactaagtgg tcgatcaatt
     8521 cttgtgcttc tttttctgtg attactccat tatccaaatc acgttggata tagatatcaa
     8581 ggaatgctga gatacgtccg attgacatcg cagcaccatt ttgtgatttg attgctgcta
     8641 aatatccgaa gtatagccat tggacagctt cttttgcatt tgcagctggt ttagaaatat
     8701 catagccata tttcgcagcc atttctttca tttgcgctaa tgcacgatat tgttcagtga
     8761 tttcttcacg taaacgaatc acttcttcac tcattgtatg ataaccagtc atatcatgat
     8821 cttttttctt ttgttccatc aaatagtcga ttccatacaa tgccacacga cgatagtcac
     8881 cgatgatacg tccgcgaccg taagcgtctg gaagccctgt aatgattttg tttttacgag
     8941 cagcacgcat ttcagcagta taagcgtcaa atacaccttg attatgtgtt ttgcgccagt
     9001 cagtgaaaat atgtgtcaat tcatcgtttg gtgtatagcc attgcttttt agcgcattgt
     9061 tagccatatt gattccgccg aacggcatga atgcttgttt caaaggtttg tctgtctgta
     9121 gaccgacgat tttttccaaa tctttatcca aatagcctgc atcgtgtgaa gtaatagttg
     9181 atacgatttc tgtgtccata tcatagacac cgttacgctc gaattggata tcatttaact
     9241 tttgcaattc atcccataat ttttctgttg cttctgttgg gccttccaaa aagctgtcat
     9301 caccgcgata ttcagtgtag ttattttgaa taaagtctct agtgtctacg ccttctttcc
     9361 atttggtacc tttaaatcca ttccattgct ccattgtatg gacctcctaa atttctgttt
     9421 tatgtaacag tttttacgtg attagtataa cacagcaccc tatctttgca agggttttct
     9481 tgttttttat ttaacaattt ttatgtttta tttacatata tttaaatcaa cgttgacata
     9541 ccaacattta agcattgtga acactttcat ctttttttgc aaacgtataa ggatttatta
     9601 aaaatgaatg aaaaagagac gccacctgta ttaatacaga tggcgtctct tcattaaaat
     9661 actacaacag ttacgactcg atgaaaatct caggagcatc gataacttcg atgacttctc
     9721 cacctttttt ctcatccatc gcaaatgatc cattcgatgt tcgatcacct atagggaaat
     9781 cagttgggtc aatcgttaac tgctgccctt tttgattcat caaggttatt tcttttgatc
     9841 ttccttccga catatagata atacggtgcg gatttttttt cagctcacgc atgaccgtca
     9901 ctccccgctt cgcacgtgaa gtttggctga tttcttgagc aagcatgcgt ttaacagctc
     9961 ctcgctgagt aacgattacg atcggcgtat caccttctgc taacacaagc agcccgttga
    10021 taatcctatc tccatctttc aaattcatag acttcactcc agctgccttt gctccaacaa
    10081 cgggaacatc tgttaaagga tagcgcaaac ccattccttg atgcgttact aagaaaacat
    10141 ctaagcctgg ctgatcttct ttcagataca cagcaatcag ttcatcttct tccgccttta
    10201 gcttcataca gctgagcgga cggctcttat aggtgcgcca tggttcgaac tctgtcattc
    10261 gtgtttgctt gatcaatcca ttcttgctga tgaatacaaa tgttttctct gcttgaattt
    10321 tttgatatgg gaaaacagct aaaatcgatt cgtctacaga cagattggag attgtttgag
    10381 aaatgtgctc accagcatct ttccatttca aatcgggtag ttcatggaca gggcggtaga
    10441 tcacatttgc tttatttgtg atcagaagaa catggtccaa tgtactcaat tcacctgagt
    10501 atagcaagta gtcgccttct cgcatcccga tttcttctgg tttggaagca ctataagaac
    10561 gaaggcttgt tcgcttcaca tagccttctc gcgtcacact gacaattacg tcttcttgtg
    10621 ccactaagac ttgcgtatca attttgattt cttcgatttc gtcttcgatt gtcgttagac
    10681 gagcggaaga ataatttttt ttcacttctc gcaattcttt tttcataaca gagaaaagct
    10741 ctttgtcatt tgaaaggatt ttattcaact ctgtgatttg cgcaatcaag ctttcggatt
    10801 ccttttgaag ctctgtgata tccgtgttcg tcaaacggta taattgcaat gtgacaattg
    10861 cttctgcttg ttcttctgta aattgaaaga cgtcgactaa attctttttg gcgtcttttt
    10921 tgtctttact ttcacgaatc gttgcgatta cttcatccag aatcgataaa gctttcatca
    10981 atccttctac gatatgctgt cttttttgag ctttggctaa atcgaattga ctacgttttg
    11041 ttatgacttg ctttcgatgc tcgatataac ttcttaaaat gtctttcagt ccaacttgat
    11101 gcggagtcat atggtcgata gcgaccatat tgaaattgta attgatctgt agctcagtgt
    11161 ttttgaacaa ataattcaaa attccttgag cattggcgtc ttttttcaat tcgacgacaa
    11221 tttgcagacc tgttctatca ctttcatctc gtacttcagc tattccatcg attttcttat
    11281 tcaaacggat ctcatccatt tttttcacca aggtcgcttt atttacttca tatgggattt
    11341 ctgtgatcac gatttgctgt ttattaccct tcattgcctc tatctttgtt ttcgaacgaa
    11401 gaataacttt tcctcgtcct gtttcataag cttttttgat ttcatctttt ccttgcaaga
    11461 tccctcctgt tggaaagtca ggtccaggaa tatattccat caatttttca aggctcgctt
    11521 gtggatgatc gatcatatag attgtgccat cgatcacttc agctaagtta tgagtcggga
    11581 tttctgttgc atatccagca gatatacctg tcgatccatt gacgagaagg tttgggtatc
    11641 gagctggaag gactgttggt tctttttctg tatcatcaaa attccacacg agatcgactg
    11701 tttctttctc gatatctgct agcatctctc cacttaactt ggataatctg gcttcagtat
    11761 aacgcatcgc agcaggtgga tcaccgtcca tactcccgtt attcccgtgc atttcgatca
    11821 gtacttcccg caacttccag tcttggctca tgcggaccat cgcttcataa atactgcggt
    11881 caccatgagg gtgataattc cccatgatat ttccgacaga ttttgctgat ttacggaatc
    11941 ctttgtcata cgtattgcca tctttgttca tggcaaataa tatccggcgt tgcactggct
    12001 tcaatccatc acggatatca ggcagtgcac gttcttggat aatatatttg gaataacgtc
    12061 cgaagcggtc acccatcact tcttctaaag ttaattcttg tacttcttgt cgattttcca
    12121 tcaggtgacc tcctattcta cttcaaataa ctgattgttt tcatttttat ctgctcgttc
    12181 ttcatctaat aaatcattag aaactgaagg agagatttca gtatcctctt ttttatctaa
    12241 gatactgcca tcttcttcga gcgtaaattg cacgtgattt tcgatccatt ttcttcgagg
    12301 ttctactttg tcacccatca gtgtggttac tcgacgttca gcttgcgcag catcatcgat
    12361 acggacgcgg atcaacgtac gggaagtcgg atccatcgtt gtttcccaca attgttccgc
    12421 attcatctct ccaagtcctt tatatcgctg cagcatatat cctttgccga cttttttaat
    12481 cattgctgcc aattcgtcat ctgtccacgc atattcaatg acttgcttct ttccttgtcc
    12541 tttggatact ttatataaag gcggtaacgc gatatatact ttcccagctt caatcagcgg
    12601 tttcatataa cgataaaaga aagtaagcag taatacttga atatgggcgc cgtctgtatc
    12661 cgcatcggtc atgatgatta ctttgtcgta attacagtct tcgatagaaa actcaggacc
    12721 gactcctgca ccaatcgtat agatcatcgt attgatttct tcatttttca agatatcttg
    12781 cattttagct ttttcggtat tgatgacttt tcctcgtaaa ggtagaattg cttggaactt
    12841 tctgtctctt ccttgtttag cagatccgcc agcagaatcc ccttcgacta aatacaattc
    12901 atttttctta gggtttcggg attgtgcggg tgtcaatttt cctgaaagaa gagattcgcc
    12961 ttttttacgc ttcttcccat ttcggctttc ttctctggct ttacgtgctg cttctctcgc
    13021 ttctctggct ttgattgctt tacggaccaa catctggctc atttcgctat tttcctgcaa
    13081 ataaaagccc atttgttcac tgatgacgtt atctactacg gtacgagcaa ctggcgtacc
    13141 aagtttttct tttgtttgcc cttcaaattg cagaagattt tcaggtacac ggatagaaag
    13201 tacagcagct aacccttctc tgaaatcact accttccaga ttcttgtccc gttctttcag
    13261 caaaccaact tttctcgcat attcattata agatttcgtc atcgccgctt tcataccagc
    13321 ttcatgggtt cccccatctt ttgtccgaac gttattgaca aaagataaaa cattttctga
    13381 ataaccgtca ttgtattgat aagcgacctc tacttcgata ccttcttttt ctcctgaaaa
    13441 ataaacaact ggtgtcaatg tatctttttc ttcattcaga taatcaacaa attctttgat
    13501 tccttcttcg taatgaaaaa tttccttgac tggttcttct ccacgaagat cagaaagaga
    13561 gattttaacg ccttttagaa gaaaggcaga ttctcttaac cgttcggcta aaatttcata
    13621 tgaaaatttc gttgtactga atattgtatc atctggtaaa aaatggacag tcgtcccgtt
    13681 tgcttttttt gtttttccta tctttttcaa agtaccgtca ggtttaccgc cgtttttaaa
    13741 tttctgctga tactctacgc catctctaac gatcgttaca attagccatt tcgataaggc
    13801 atttaccaca ctggctccta caccgtgcag tccaccagaa gttttgtacc ctccttgacc
    13861 aaactttccg ccagcatgca gcacagtaaa aatcacttca actgttggta ttccggaagc
    13921 atgcattcct acaggcatcc cacgtccgct atctgcaaca gttatactat tgtcttcatg
    13981 gatggtcaca tcaatctcac tgccataacc tgataatgct tcgtcaactg cattatcgac
    14041 gatttcatag actaaatgat gcaagcctcg gctgtcagtg gatccaatgt acatccctgg
    14101 tctttttcta actgcctcta atccttccaa tacttggatg gacgagtcat tgtattcgtt
    14161 gtttactttt tttgccaagg caaacgctcc ttcaataata ctttgcggca aaaccgcacc
    14221 acgattatca tactagaaaa ggtcgtgaaa aaaaagaggg tagacgagaa atcaatttta
    14281 attatctcct aaccgctttt tcgacattcc cctctatcga tcatctcttc tttgtggtca
    14341 tttttatttt tggttttctt tcaacttacc aagttcaatc ttaatacaac gatccattac
    14401 gatatctgta cgtcctgctt ttcttagcat ctcagctgct tctttgtttt caatccctaa
    14461 ttgtgcccag aacactttag catcagtttt caaaaaatca cctgctattt caggtaaaaa
    14521 ttcactccgt ctaaatacat ctacgatatc gattggatca tcgatttctg tcaaattcgc
    14581 atagactttc tcgcctagaa tttcttcacc agccaataat ggatttactg gtatgatttt
    14641 atatccattg tcttgcaata cctgtgcaac catgtaactt gttcgttctg gtttattgct
    14701 caagcctacg acggcaatat tttttgcttc ttccaaatag ttgaaaatcg tttcttgtgt
    14761 tggatttttt acagacattt ctgccacccc ttgcttttct ttttattcca tctattatac
    14821 ttgtatcttt cattttttca attgttcctg ttacctattc atgctaaaat aaaggatagt
    14881 tttcaacttg aaagagggta aaaaatgaaa ttgatcttat tacttatttt agcatatctt
    14941 ttaggttcta ttccttccgg tgtctggatt ggcaaattgt ttttcaaaaa agatatccga
    15001 caacacggga gcggtaatac tggaacgacc aatacatttc gtgtattagg caaaacagcc
    15061 gggattgttg tcctgcttat ggatatttta aaaggtacat tggctacttg tttgccgatg
    15121 atcttccacc tttctgggat taaccctctt tggtttgggg tatgcgccat tcttggccat
    15181 acatttccga tttttgctgg gttcaaagga ggaaaagctg ttgcgacaag tgcaggaatg
    15241 cttttaggat ttaatcctgt attttttgtt tattcttgta tcatctttat cgttagttta
    15301 ttttgtacaa gtatggtgag tttgagcagt atgatcagtg cagtattgat cactttatct
    15361 acgatcgtcc ttccttatgt agctcctgtg attttggcta agcccaattg gttactgacg
    15421 atcattgcct ttttagtttc ttcctttatc ttttatcggc ataaagacaa tatcaagcgt
    15481 atcagaaacc atactgaaag tcgaatcccg tttggtttga atagcagcaa gaaaaaatcc
    15541 tgatactttt tcattccaaa gagataaaac gggagtgtga caaatcgatg tcacactccc
    15601 ttattactta caggatagct tttttacaca ccttggtaaa cggtgttccc tgctaacttc
    15661 tcggtcacaa cctcttactt cactgtgatg gaatattttg tcttgaagat ttcatgggca
    15721 cctagttgat tgatccctac tttttccatc aagtttccac tactgttcac cgtgtcagcg
    15781 attccgcacc acggttcgat acaaacgaaa ggcgcttctt ttggataagg agaccagatc
    15841 cctacataag gcatatcttt atagcttaaa gttacgctat gggaagattt ttcacttcga
    15901 atggcgtacg catttagacc ccttgtttca aaaaccaagg catcttgctc aaaaagttca
    15961 cgattcaaag ccagattcgt atttgtctga cctaacgtct tttgatccat atcgatgaat
    16021 gggcctttca atggtaggcg taatcttgat ttcaatggag aaaatgccag atagaaatct
    16081 tcaaatgaca atccttcttc aagaggtaca ttgaaagcag gatgtccacc gatagaaaag
    16141 aacatttctt tttcaccggt atttgccact tgataatgaa ccgtgatgcc gtctcctcct
    16201 aattcatacc tgatcactaa ttcaaaatca aatggatact tttctaatgt ctccggcgta
    16261 ctccttaaga tgaaactagc catttcttgt ccatgttcaa tgacttcaaa atccatatcc
    16321 cgagcaaatc cgtgttgccc catttgatat gttttccctt gataaacata ctgatcatct
    16381 tttaaacgtc caacaaaagg gaataaaacc ggtgcatgtc tgccccaata cgctggatca
    16441 ccttgccaga tatactctaa accatgttct tttgatttca gactgatcaa ttccgcaccg
    16501 tgttcagcga tttcggcgat cagctggtca ttttgaataa taacagtcat tgccattcct
    16561 ccaacttcga cttacttttt aaaatgggaa ggctggaaca aacatttcta tctgccccag
    16621 tccccttact tctaataact gtgttttgct aactcgtctt taaaacggga attcaatact
    16681 tttaaataag ttcccttcat gcctaacgaa cgagattcaa tgattccagc tgattccaat
    16741 tttcgtaaag cattgacgat cacagaacga gtgatgccga tactatcggc aatattagaa
    16801 gcagtcagac gaccttcatc tccatccaat gcttcaaaga tagcttgtac agccttcaat
    16861 tcgctataag ataatgtgtt gattgccatt tggacagccg ttgcactccg tacatctgct
    16921 tcgatgcttc gagacttctg ataaaggatc tgcataccga caaccgtagc tccatattct
    16981 gctaagacta gatcgtcatc tgcaaacgat tgttccatac gagataagat aatcgtaccc
    17041 aaacgttcgc cagctccaaa gatcggaacg acagtcgtca gaccaaatgg atatttctct
    17101 cttgactcta ccggaaatgc agtaatatca ctagtaattg ggatattagc ttcagttttc
    17161 atcaactgtg ccactgtatc agtataagat tcaggaaatt gtttctcaac aaacattgtt
    17221 ttgattcgtt cattgttcac atcgtgacgt tcattataac ctagtaatac tccgtcactt
    17281 cctatgatat aggtgttgct gtcaagaata ccacctagtg tgacagccat tttatcgtaa
    17341 ggcaaatctg cttgcatgtc aaaagtattc ttttgctgca aaagtgtgtt tatcttgcgg
    17401 gttttcgtta gcaagtctgt cattgtcgtc ctccgatttt ttataaaata tagcgactta
    17461 aatcttcatt tgccgcaatt gagccaagtt tgtcatccac atatgcttct gtgatcgtta
    17521 tttctcccat ttgcatatct ggtgcttcaa ataatagatc ttctagtagt ttttccaaaa
    17581 tggtatgcag tctgcgtgcg ccgatattat ctgtgtcacg gttgacatcg aaagcgattt
    17641 gagcgatccg ttcaattgct tcttttgtaa acgtaactga cacattttct gtaccgatca
    17701 acgcgacgta ttgttttact aaagcattat ttggttcggt cagaatcttc acaaaatctt
    17761 cagctgtcaa atcatctaat tctacccgta tcgggaagcg tccttgaagt tctggaatta
    17821 gatcacttgg tttagacaaa tggaaagctc ctgaagcaat gaataggacg tgatctgttt
    17881 ggatgatccc gtattttgtg tttacttgtg aaccttcgac aattggcaat atgtctcttt
    17941 ggacgccttc tctggatact tctccagatt gctgtgattt agaagtgatc ttatcgattt
    18001 catcgataaa aataattcca ctttcttccg ctaatttgat tgcctcacta tggatatcag
    18061 catccttgac taattttgct gattcttcct tgatcaataa ctctaaagct tctttgactg
    18121 ttaccgtccg ttccactttt ttcttcggtg tcaaagcacc tagagtttca tttaggtcga
    18181 tccccatttg ctccaatcca ttgttcatca ttggtgcagg tttcttttgg tcttcaactt
    18241 caatggttac ttcacgacta tccagtaaac ccttttgtag ttgttccaag actgtacggc
    18301 gattgattcg aatatcttct gtcacttctt cttgcggttc agcggtattt tgctgactag
    18361 cattaaaaag attcatcatt tgttcaaatt gattagtgga ttgtttctgt tcttttttga
    18421 taccaggtac caagattttt accaaacgtt tttctgcatt ttttttagca cttgtgtata
    18481 cacggctgta ctgctctttt tctacgattt ggatcgcatt ttctactaaa tcccgaacca
    18541 ttgattctac atctcttccg acataaccga cttcagtaaa ttttgttgct tcgactttga
    18601 caaatggtgc attgacgatt tttgccaaac gtcgtgcgat ttctgtttta ccgacccctg
    18661 taggtccgat catcagcata ttttttggtg taatatcttg ttgcattttt tcatctaact
    18721 gcaaacggcg atagcggtta cgcaaagcaa cggcaacaga tttttttgct gcgtgctgtc
    18781 ctacgatata ttcatctaat tcacttacga tttgtcttgg tgtttgtttt aattcataca
    18841 tatctactca cctcttacag ttcttctacg ataatattat gattagtaaa gatacagata
    18901 tctgcggcaa tatttaacgc attttctgca atttctttcg cactcatgtc gttttgagca
    18961 tagtttttca ttgctcgggc tgcagccaac gcaaaattcc ctcctgatcc gatagctaag
    19021 ataccatcat ctggtgtgat aacttctcct gtacctgaaa caagaagcat ttctttatca
    19081 ttcattacga tcagcatcgc ttcaagtttt tgcatagatt gctgtgtccg ccattcttga
    19141 gctaattcga cagctgcgcg ttgtagattc ccgttatatt cgtttagttt gccttcaaat
    19201 ttttcttcta aagtaaacgc atctgcaaca cttccggcga aacctacaac aacttctcca
    19261 ttgtagatac gtcgtacttt ctttgcagtg cctttcatga caacagattc acccattgtt
    19321 acttggccat ctccagccat agcaaatttc ccgtcttttt cgacggcaca gatagtggtt
    19381 gaatgaaatg gtgattcgac catgtttgtt tcctcctaaa tttgttcttt tccttatttt
    19441 tacgctcttg gatggaaaga acgatagttt ttttgtaaac tttcttttgt tacatgggca
    19501 tagatctggg tagtcgataa attggcatgt cctagcaatt cttggactgt ccgcaaatct
    19561 gccccattat ttaataaatg agtagcaaat gtatggcgca gcatgtgagg atggatatca
    19621 ctatccaaac tgcttttttt gatcatttga ttcaagacat attcaattcc agtaggcgtg
    19681 attggttttc catgatgatt cacaaaaacg atatcatgct cttcgtgata ttttgtcatc
    19741 aatacctggc ggccttccct gaaatattct tgcagagcat cttgagcaaa agaacctaga
    19801 ggagcatatc tctctttgtt ccctttacca tggatcaaca tgacctctga atcaaaatca
    19861 atgtctgata ccgacaaact gctacactca cttaaacgga tgcctgaccc gtaaaggact
    19921 tccagtaaag cgcggttcct caaatccaaa ggactatctc ctgctacgct gtcaaaaagt
    19981 gcttgcattt cattttcata aaaaaaacgt ggcagtctca aatttttctt tttgagatga
    20041 acgtaagaaa atggattttc ttttatcact tcttctttga gaagatactg ataaaacgaa
    20101 cgtaggctgg ctatcttgcg actgatagaa tttctgctat agctaggacg atgatcagct
    20161 aatgcactca aatagacacg aaccgtaaaa tattccgcct tcagcagatc agcgtctcca
    20221 gattcctcca aaaaatgttt gaaatggaga atgtcttctt catatgcttc tttcgttttt
    20281 tctgaatatc ctctttcgac aatcaaataa cgcaaaaatt tttgttccca cgtggcttct
    20341 gtcattttct caccttcctt ttgtcccaga gaataattta gcacagcgtt tataaaaaga
    20401 caaataaatt gtcagaattt aaccaatatt tctaagtttg ttcacaattg gcgcaattcc
    20461 tcacattttg tttgagaaat tcttaagaaa aacgcaagaa aaagagcgag actatccgtc
    20521 tcaccctctt catggagttt ccttactcat ttgggattgc agttttttct aattctgttt
    20581 ttattgcctc attagctttt aaagctcgtt gtgcaattgc ttcatatctt gcttttttgt
    20641 ctcgaatgcg ctctggcagt tcaggaaaca gaccatagtt ggcattcatc ggttggaaat
    20701 gttttccttc cgcatgagta atgtagtaag ccatacttcc aatagctgtt tcttgtggaa
    20761 actcgactgg ttccatttct tttgctaagc gtgcggcgtt gattccagca agtagtccgc
    20821 tcgctgcact ttcaacatag ccttctacac cagtcatctg acctgcaaag aacagatctt
    20881 cgcgtttcgt tgattggtaa gtcggtttca gcaattctgg cgaattcata aagctgtttc
    20941 ggtgcatcac accatagcga acgaattcag cattttctaa cccaggaatc atccggaaaa
    21001 cacgtttttg ctcgccccat ttcaagtgag tctgaaagcc cacgatgttg tataaagaag
    21061 ctgcagcatt gtcttgacgc agctggataa cagcataagg acgtttgcca gttttaggat
    21121 cttccaatcc aactggtttc ataggtccga aaagcatcgt tttgaatcct cgctgtgcca
    21181 ttacttcaat tggcatacat ccttcaaaat atttttcttt ctcaaaagat ttaagttctg
    21241 ccacttcggc attgattagt gcctcatgga aagctttgaa ttcctcttct gtcatcggac
    21301 agttcaagta agctgcttct cctttgtcat agcgggactt caaatatact ttatccatat
    21361 cgatcgtagc tttgtctacg attggtgcag ctgcatcata gaaataaaaa ccatctgaac
    21421 cattgaatgc tttgatgctt tctgctaatg gatgagaagt caaaggtcct gttgctacta
    21481 cggtgattcc ttccggtatt tcagtaattt cttcgtttat cactgttact aatggatgct
    21541 ctttgacttt tcgggtaatt gtttcagaaa aagaatcgcg gtcaacagct aaggcaccac
    21601 cagctggcac tgctgtttca tctgccgaag tgattactac cgaattcaat cggcgcattt
    21661 cttctttcaa taaccctact gcattagcca aactgtttcc tcttaatgaa ttggaacata
    21721 ctagttcagc aaaattactt gtgtgatgcg cctcagtcga tttgactgga cgcatttcat
    21781 ataaacggac agggactcct gcttgtgcga tctgccaagc agcttcactt ccggcaagcc
    21841 ctgctccaac aacatttacc attttcaatg aaagaacctc ttttctatta tttttggatg
    21901 tcttcttcgt aatctccatt tacacagact acttgtttac cgcctttgac tttcttctcg
    21961 accagatatc cgtcacattt tggacaattt ctgcccactg gtttatccca agaagtgaat
    22021 tcacattctg ggaaacggga acaaccatag aatagtctgt ttttcttaga ttttcgttca
    22081 atgacttgtc cttcatgaca tactgggcaa gtcacaccga tttcttttac gattggtttc
    22141 gtattccgac aatcaggaaa attactgcaa gcataaaact tcccatattt ccctaatttt
    22201 atcaccatcg gatgtccaca gacatcacaa tcgaatcctg ctggttcatc tttgatttga
    22261 attttttcga ttttttcttc cgcattcgtc agttcttttt caaacggttt atagaaacga
    22321 tcaaccactt tgacccacgc ttccgtgcct tcttcaattt tatccaaatc tccttccatt
    22381 tctgctgtga aatggatatc gacgatttga gggaagaatt cacagattaa tgaattgaca
    22441 atttctccta gttcagtcgg ctcaaatctt ttttgtgtca attttacata gtagcgtctt
    22501 tggatcgtat caagtgttgg tgcataagtg gaaggtcgcc ctaccccgtt ttcttctagt
    22561 gcacgaatca acgtagcctc actaaaacgt gctggtggtt gagtaaaatg ttgttttggt
    22621 tcaatatcaa cagattggac tacatcgcct tcttcaagtt ctggaagaat attttctttc
    22681 tcttctttgc cgtcatctct accttccaca tacacttgca tgaatccttt gaatttgatt
    22741 tttgaaccgt tcgcaatgaa gatgacacca ttttgttcta atgtcacttt cattgtatct
    22801 aaaatagctg gtgtcatctg actagccaca aaacgtgacc agatcaatgt ataaagtttc
    22861 aattgatctt tatctaaata ttgtttgagt tcatctggtg tacgaagcac actcgttgga
    22921 cgcacagctt catgggcatc ttgtgcgcct tgagcatttt tgatctttcg gtgatcatgt
    22981 ctagaaaatt cttttccata cgtatcttca ataaatgctg cggcctctgc ttttgctgta
    23041 tcggcaatcc gggtagaatc agtacgcatg tatgtaatca agccgactgt tccttgttta
    23101 cccaaagtga ttccttcata taattgctgt gctaccatca tggtttttct tgttcgaaag
    23161 tttaacttac gggcagcttc ttgttgcagg ctacttgtag tgaaaggatt cgcagggttt
    23221 cttttgcgct ctttcttttc tactttttta acttcgaagt ctgttccatc aattctagca
    23281 gtgacttctt ttacactttg tgcatctggt aatttctttt tcttaccgtc gattccccag
    23341 aaatttgctt tgaatttctt gcgagctttt ttaaaattac cgtcgatgct ccaatattct
    23401 tctggaacaa attctcggat ctctttttca cggtcaataa taatttttaa agcgacagat
    23461 tggacacgtc ctgcacttaa ccctttcttg accttacgcc agagaatagg actgatcgaa
    23521 taaccaacga ttctgtctaa ggtacgacga gcttgctgtg catctactaa atctacatcg
    23581 atcgttcttg gttccttaaa agctgctttg actgcgtctt ttgtgatttc attgaagacc
    23641 acccgatttt tttctttcag atccaaccca agtaggtacg ctaaatgcca agcaatcgct
    23701 tctccttctc tatccgggtc acttgccaag taaacttttt gagctttttt tgctgcggct
    23761 ttcaggcttt tgatgacatc gccttttccg cgtatagaaa tataatgggg ttcataattg
    23821 ttttcaaaat cgatacccat tttacttttc ggtaaatctc ttatatggcc aacactggcc
    23881 attactttat agtttcgtcc aagatatttc tcaattgtct tggcttttgc aggtgattct
    23941 acaatcacta aatatttata cgccattact gaatggactc ctttccattg tcgtgttcct
    24001 actattaaaa gaggattcat acaaatcgta gctaatcata tccattcaga aaacgtttgt
    24061 caagaaaagc aaatgaaaag tatggtgtta ttctttaaat tctgccaaga tatcttcacc
    24121 cgaaaccgtg caaactgcac cgtcttggat caaatgatga catccggtag aatgttctgt
    24181 taaaatattt cctggaacag aaaaaactgt tcttccaaga tccaatgctt gctgtgctgt
    24241 tatcagagag ccgctttttt tcttggcttc aaagacacat gttcctttag acaaagctgc
    24301 gataatccga tttctcattg gaaaacaatg ctttttcggg ccggattgag gaggatattc
    24361 actcaaaaga agatgatcat ttgcaatcac ctcttgcaag tcacgatttt cagcaggata
    24421 gacttgctct atccctgttc caatgactgc gattgtccgt ccaccatgag agattgctgc
    24481 ttggtgaccg tatgtatcta tccctttcgc gcagccactg acgatcacat atccagcttc
    24541 tatcactggt tttagtaaat aataaactgt ttttttggct aaagcagaag tgtgtcttcc
    24601 accaacaacg cttaacatgt tacaagaaag taaagataga tcaccattat aaaacagtac
    24661 aattggcgga taggtcaagt gaagcagctg agggggatat ttgggatcaa agcaagtgat
    24721 aaacgactgt ttcgattgga ttttgcccca gttagcgtga atttcctgcc aacttttgcg
    24781 aaacagctcc cggtgtttgg ttattttacc tatcttaatg atgtcttcaa atccgatttc
    24841 tttataagga tactgcatca tccagttagc aagtgcccat tttccttgac tactgattcc
    24901 ttttgtataa gcaagtttca ataaattttc ttctatttga tacatcataa aaccgccttt
    24961 cgtctctctt tctaataaga tacgtaaaag cggctgtttt ttattgtaaa tattttttta
    25021 caggtgcaaa acttttacga tggattggcg taattccttg tcgttcaagt ccttctaagt
    25081 gttcctttgt tccataacct gcattatgcg agaaaccata tccaggataa agcacgtcat
    25141 attctttcat caattggtct cgatatactt tagcaatgat acttgcagca gcaatcgaca
    25201 cagatcgtgc atcccctttg attatttttt cctgctgaat aggcaaatcc aaggtcatcg
    25261 catcgatcaa caaatagctt ggtacaatgg acaatttttc tactgcttgg atcatcgcta
    25321 atttacttgc ttcataaata ttcacatcat cgattgtctg ctgatcaacg atcccgatcc
    25381 cgattgccag ggctttttct tgaacttgtt gataaagaag ttctcgcttt ttctctgata
    25441 attgtttgga gtcattcagc cctaatatga tctcattttt cggcaagata actgcagctg
    25501 ccacgacagg tccagctaat ggtcctcttc ctacttcatc aatgccggca atccattggt
    25561 gaccttgtgc gtacccttgc ttttcaaagc aaaacatttc ttcatatttt tccttaatta
    25621 atgcttcctt tttcaatcgt cgttcaaaag aagccagtgc ttgctgcacg cctttgcgtg
    25681 gatcatttct taatgattct agtgtaggat catctattct ctgtatgctt ttcaatcgtt
    25741 ctttgatact ttggatggat tcagtcatca cttttttgct ccatttcttc gcaacgatcc
    25801 agtgtgtatc gtccaagttt tccttgacga atatcatgca cgactaattc gctgccacga
    25861 tcatagtctt ctttataccc acgttttgct gtaatatcca tcagtaattc cggtgccaat
    25921 ttttcttctt gctcgattga taaaccataa cgatcgctga ttcttcctga ataatatcgg
    25981 gcaaaaaagt ctaatccgta aatcgctaaa tcatctaaat ggacaagctg gtctttgatc
    26041 gcgcctgtca gcgctagttt tttgccgatt tcttcatctt caaatttggg ccataaaatc
    26101 cctggtgtgt ctaacaattc caactcatta cctaaacgaa gccactgctg accttttgtt
    26161 acgccaggct tatttcctgt ctgtgcaatt ttcttgccta ctagtcgatt catcaacgta
    26221 gatttcccaa catttggaat acctaagacc attgcccgaa tagcgcgagg cttgatcccc
    26281 cgagcagcat ctcttgcccg tttttctttc aatgcttctt tagccgcagg tactagacct
    26341 ttaattcctt tactttcttg tgccgtgata gctaatgcaa gatggccttg tttacgaaaa
    26401 tattcttgcc acagctttgt ctgttgtgga tctgccagat ccgctttatt caataaaaca
    26461 aggcgaggtt tttgctgaat gatctgatct agcattggat tacgagaaga taaaggtaat
    26521 cgtgcgtcta ccaattcaaa tacgatgtcc acatatttca ttttttcaga aacttctcgt
    26581 cgggcttttg ccatatgtcc cggaaaccat tggatggtca ttgttctctc cattcctttc
    26641 ataccggaat attccccggc tttacttgtt ttttttcttt ttcaatataa attcactttt
    26701 ttattataaa gaaattccat ctattagtta agtgaaagtg aaccagtcct cattctatca
    26761 catcttcact tttttgatga tgtaaatttt tattttggtt tctatatatg aatctaaatt
    26821 tttgacaacg tttcctaaat aagagatgat agacgaacaa aacagaaagg agacgaaaca
    26881 aatgaatagt atggtttttg ttaattttcc tgttgctgat gtcaatcgtt ccgttgcttt
    26941 ttatgaaaag ctgggtttta aaaaaaatga agaattttct actgaagaag ctggttcaat
    27001 ggtatgggat gacacttttt gggtaatgct tctctctcat gatttttata aaaaatttat
    27061 aaaagataaa gaaatagctg ataataaaaa aacaagtggt gctttgattt cgtttagtgt
    27121 tgaaaacgcg gatgaagtaa aaaaatttgc tcaaattgca aaagaaaatg gtggtacttt
    27181 ccacgaagta gatatgggaa tgcctgaaga agaaatgttt tcattagaag tccaagatct
    27241 agacggaaat acattagaac ccgtatggat gaagatgtaa gcagataact aatctgacgt
    27301 tttttataac aaaaaaacaa aggcggatga tacgataagt attctccgcc tctatttttt
    27361 tcattcgtac aatctctttt ttacagttta taaaagcagt cttctcaccc tttttttaat
    27421 tgttagatgc cagtgtatgt aaatcaccaa tgtgtcatga cacattggtg attttatggt
    27481 atccttttat tattaactga caaaggagag aatattttga acactttgat tgcaaaagac
    27541 gtttttagat tgcccgaaat gaatgcaaga ttgttgtcga cctctgctct tttattagcc
    27601 cttgatgtca tcttatacaa gatagcgatt ggtcctgctt attttcaaat cacattcgga
    27661 tttttaagta tggcgcttat gggttatcta tatggaccga tctgggctgg tttgcttgaa
    27721 atgttgtcga acactttaaa tttcacgata tttggttcag gaacgtttca agctgctttt
    27781 cttatcacgg ctttccttgg tggatttatt aatggcttat ttttatatca taaaaagata
    27841 aacctgcctt ccgtcatcgc tgcccaatta ttgattatga tcccagtcag cctttttatc
    27901 aattcttggc tgatgtctgt tttgtttggt gcagatttca aagtgatttt tctaggtaga
    27961 gtcatcagga atatgatcca aatccctatt caaataatgg ttgtttattc atttatcaaa
    28021 actttagagg ctagaaaagt gtttaaacga gctgtttgat tttacgtact aaggtagtaa
    28081 actgattttg gattaaacaa taaagcgtgc agtctcaaca gattgcacgc tttattgttt
    28141 ctcactggat ccattttatt tcatcaagtg gataatagac aaatcttgct ttacctagaa
    28201 tatcagtttt attgatcgtg ccaaacgaac gactatcttt tgaaactctt cgattatctc
    28261 caagtacaaa ataattatct tccggaagct tggattgtcc cgttagctct tgtagtgtaa
    28321 agtccgtcgt ataggatgca tttgcatgat ctgatttcag gtttttagtt agataaggtt
    28381 ccttaactac tttcccattg atcttcaatt gatcattttg gtagctgaca ttttctcctg
    28441 gaagaccgat tactcgtttg atataaatcg tgccatctgc taattgaaaa acaacaatat
    28501 caaatcgtct gatctccgaa aatttttcca tcacaaccat atcaccttgc ttcaacacgt
    28561 tttccattga attgccttcc actggtaccg ggatgaataa aaatccccgc aacatgaacg
    28621 caaggaatac agaaacaagt aagtatttga atacaagcca gaagcgatta atatagcgtt
    28681 gtttttttgt caatctctat caatccatcc ctcgtttttt cattctttct ttattataag
    28741 aaaaatatca aaaaaatgcg actagatagc tgaaataaaa ataattcttt caattaggct
    28801 attggacaaa aaactttttt gatcataaag tacaaaacta tctcttatat gtcatgatta
    28861 ttttctaaat atttttccca tgcttcgtca aagatatcca tggacggcaa atagtcgaca
    28921 ttcagttcca gataattaga aatttcttcg tagctagagc tgtgcttagg aaattggatg
    28981 tctttaccgg cttctgtagc gaaaacagat aaagcatcat gtgtgccacc gcctcgcagt
    29041 gtcattaaat aatgaaaaaa gcttcgattc acccttcgtt cctccaattt tcttcgataa
    29101 aggcagcccg gcgtgcatgg tttcttttaa aattttcagg atgcttttta taatactctt
    29161 gatggtcttc ttctgctaga taaaatggtt gggctggttc gatttttgta acgattggct
    29221 gttcgaaacg tccactttca gctaactgtt tcttactttt ttcagcaatg atccgctgtt
    29281 cttctgtcaa ataaaagatc accgggcgat aattgtcacc gcgatcctcg aattgtccga
    29341 aagcgtcagt tggatcagtt tgctgccagt aaagttctac taattgttca tatgaaatca
    29401 atgttggatc atagataatc tccactgctt ctgtatgtcc agtcgtttgg ctttttactt
    29461 gttcataagt cggatctggt acatgccctc cagtatatcc tgacatcact gtatggatac
    29521 caggaagcgt gtcgaaaggc tggatcatac accagaaaca gcctcctgca aatattgctc
    29581 gttccattat gattccccct ctaatactac tcatccgatg attttttatt ttcttttgtc
    29641 ttgctttcag tactgctggt gctagttttg ttggtatttg agttgtttga agcatcagag
    29701 gtatcttttg gcaaatatag actaaaccga atgtcatcat ttactaagtc gattttatct
    29761 gctttaatat acatcccgtt ttgcattcgg aattgatcca acctaagcat gatagtcaga
    29821 tcatctgtat tgacttcgat ccaatctggt aatttatagt ttctcttgat catattcatc
    29881 acatctttga ttggcaaact caatgttccg atagaaagac ttctagcttt tagttggaca
    29941 tttccgtttt ccatcacata cggatcaaaa tataaataga aatcgatagg aaaacctagt
    30001 acttcgaaag taccattgag tagtgcttca ttttccaaat aaaatttata ttcaatatca
    30061 ctatcttttt gatactcact aaggaaaaag ctgatgattt gattgacttt ttctttattt
    30121 gaattgatcg ttaagacagg atctccttgt ctttccgtaa gagctggtat ttctgggagt
    30181 tctggttccc gattagcaaa aatacggctg cctaaaaata cggtcgaacc aagtactacc
    30241 ccaagaagga taaggaaggc gaatttccag taatttgttt tctttgtttt gtttgaagat
    30301 acgtcagatc ttgttttcat gtttattgat catcctcctt ctctagccat tggttttgtg
    30361 tctcgatcag ctgatctctc actgcatttg ccatcaattg ataacctaaa ttatttggat
    30421 ggaaatgatc ttcttcatag agcacattat ttttgatgcc atttagattt tctgtcgtgc
    30481 tagttgtttg atctgttcct tcttctgtga cacctacttc ctgattcaat ccttgataaa
    30541 gcaaatcatt gattgggata aagtagcagt tcggcatttt ttttgtcacc gtttctgttc
    30601 ctttgttcca attgttaaca attgtctgca tgtcagtgat ctcaggaaag ttcaaataaa
    30661 atggattgta gatgcctaaa atgtaaatag gtgcggtttt attgagggat cgaaattctt
    30721 ccaatagttc tgtgacattt tcctgatagt ttttcagtgg ctttttaaag gaattgaccg
    30781 ttaacccgaa taaattattt tggataactt tcatcaaatc attaccgcca acagtcagtg
    30841 tgataaaatc agctgttttg atattgtttc gaatttcttc ttttgttttt actcgcttta
    30901 agatctggtc acttcgttca ccatttacac catagttttc tgtttcaacc gcggtcaaat
    30961 tataacggtc ttttagatca tttgcgacaa ggggaacgaa tcctccttgc ttggtttgat
    31021 ctcctactcc ttcagtcagc gaatctccga tagctatgta gtgaagtttt tcttttttat
    31081 ttggatcttc tctcacagta gttactggtt tcattagtgg gccagctttc ggtatagaag
    31141 cagctaaacc tgcatagatg atgatcgcaa ttaataatgg gaacaaaacg aggatcagat
    31201 gtcgtttcgt taatttcatt ttttcacctc ttgtattcga ttggttctaa tgttatcaaa
    31261 aattttatca aaaaggtagt ctttatgaaa aaagaaaaca attattttcc taattttata
    31321 aagaaaaaga gaataagctg caagcctttc aggctgaggg cttatcctct tttcgactaa
    31381 tctacataat acatgattgc aaacgcgtct ttaccagtat gcgtagcgat aaccggattc
    31441 gtatgcagta cagggatatg catgtccggg aataattctt gcaaaccctc tttgaattct
    31501 tgcgccaatt cttttgcatc cgcatgtgaa ataccgattt gtcgcacatt tggcaattct
    31561 ttcagttcat ttttcaaatt attaaaccat ttatcgaacg ttttctttcc tcgcccctta
    31621 gttacaggga ttaattcaga atgggcgaaa ttcatcacca cgcgtatgtt caaaacacta
    31681 gacagcaaac cagttgttcg actgattctt ccacctttta ccaagttatc tagtgtggat
    31741 attccgatgt ataattttgt attgtcttgt acttttttga cttcttcaag gatttcctct
    31801 actgttttac cttcttttgc taattcagct gctcgaatta cctgaaaaga taatccttgg
    31861 tcagtggtat cactgtcgat aaccgttact ttcgtttttg ttagattact ggcttgtctt
    31921 gctgcttcta ctgttccact caagcctttt gtcatatgga tcgaaatcac ttcactgccg
    31981 tcttctccta gctcatcata catcgagata aattctccaa tcggtggttg gcttgttttg
    32041 ggcagatttt ttgcttttgc catcatttcc ataaatcttt cgccgtctag ttggtcatca
    32101 tcgggatata ctgttccgtc gatcatgatg gatagcggca tgacacgaat gcctaaagca
    32161 tcgcgtacat ttttttccat cgtacatgaa gaatctgtta cgatttttac atttgtcatt
    32221 attttctctc tctctttctt taacaagatg ccttattcat gttaaactac atgtaagaca
    32281 atttctattt ttagtataac agacaaataa tgatttttca ttaattacac ctagtaaagg
    32341 agccgttttc atggaaaaaa cgaaatttaa tcgaacgtat gaaatattaa atgaagtgtt
    32401 taatgcagtc acccatggaa ttgggactgg attgagtatc gcgggactag tggttctttt
    32461 agtaaaaggt gcccacttgc attcctccct ccatattgtc tcttatgcta tctatggatc
    32521 gatgatgatt cttttatttt taacgtctac tttgtttcat tcattgattt ttacaaaagc
    32581 aaaaaaggtg ttccaagtat tcgatcatag ttcgattttt cttttgattg caggaagtta
    32641 tactcctttt tgtttgctga gtatccgagg atggctaggt tggactttat ttgtattaat
    32701 ctggttgttt gcgattcttg gcattatata taaagcgttg acgttgcata aacgggagag
    32761 agtatcaaaa gtatctacga tcatctatat ttttatgggg tggctctgtg tcgtggctgc
    32821 tgttcctctt tatcactctc ttggaatgac tggtgttatt ttgatggtag caggcgggct
    32881 ttcttacacg ataggcgcat tcttttatag cttgaattct atccgctata tgcatgttgt
    32941 ttggcatttg tttgttatgt taggtgcagg ttttatgtac ttctctgttt tattctttac
    33001 ttaataaaaa aaaataaagc tatggatggg acagctctaa ataacagcta gtctatccat
    33061 agctttttta tatcgtcaat tcgcctgtcc cgctttttac aggattctca ttacgctgat
    33121 acgtttcaaa ttgatgcgga taacgatttt tttcatctat ttctccttga ctagtattga
    33181 tcagtgacca atcagaccag tcaacaggtg gaaaataagc atctccatcg aatacatgat
    33241 ggatgactgt acggtataat atcgtacaaa atggcagaaa ttcttgataa acagctgacc
    33301 ctccagcgat gaaaaagata ccgtctgttt ctttttccag agcaagcacg tcttccacac
    33361 tatgcatgac atgcacgcct tctgctttat aggaagaatc tctcgtcaaa acaatcgtct
    33421 gacgattcgg caacggacgg ctacccatcc cttcgaaagt ttttcgtccc atcactagtg
    33481 tatttgcttc tgtcatttgt ttgaagaatt tcagatcatt tggcaaacgc caaggaagac
    33541 ggtcttcttt tccaatcaat ccgttttcat cctgtgccca aattgcagct aacattttct
    33601 catcctttct gattctaaac agcgatagga gctttgatcg ccggatgtgg gtcatatcct
    33661 tctaattgga tatcttccat ctcaaaatca aatactgact gcttttcctg attcaaaact
    33721 aaagtcggaa atgcgcgtat ttctcggctc aattgttctt tcatttgttc gatatgattg
    33781 atataaagat gagcgtctcc taatgtgtga acaaattcgc caaccgctaa acctgtttca
    33841 tgtgcaatta ggtgagtcag caacgcataa cttgcaatgt tgaacggaac gcctagaaac
    33901 acatccccac tgcgttgata caattggcag cttagccgtc cctcttgaac ataaaattga
    33961 aacatcgtat gacaaggagg caaagccatg ctaggaacat cttccggatt ccatgcagaa
    34021 acgatcaatc ttctagaatc aggagtcttt ttgattgctt cgatcacttc tttgatttga
    34081 tcgataaagc caccgtcttt tgtttcccag tgacgccatt gatagccgta gatgtgtcca
    34141 agatcgccgt atgtttcagc aaaggaatca tcggttagga tcttctcgca aaaaagcttg
    34201 ctctgctttt tatattcttc attgaattca ggatctgtca aacatctatg gccaaaatca
    34261 gtcatatctg gtccattata gtctggactt ttgatgtagc gttcaaatgc ccattcatcc
    34321 caaatatggt ttttattttg taatagatag cggatattcg tatctccttt taaaaaccaa
    34381 agcaattcgc ttttgatcaa tccaaaaggt actcgtttcg ttgttaacaa aggaaaccct
    34441 ttttgcagat caaaccgcat ttggtatccg aataagctta atgtgcctgt gcctgttctg
    34501 tcttctttac gatgcccttc ttccaacaat tttcttccta agtcaagata cgcttgttcc
    34561 atcctttttc ctcctaatct tctacccatt cactcaagta ttcccaccgt gccatttttt
    34621 cttcaagttg tgcttctgtt tcagatacgt cgttttgcaa ttcttgtaat cgagtgaaat
    34681 tatctccttg atgattcatc tcttcttgga gcaatgagat tttttcttca agttctgcaa
    34741 tctcatcttc aatcgtttcc cattcttttt gttccatgta agataatttc ttcttttcag
    34801 caggttcctt gctctgtatt tttggtttcg ctttttcagc aggctgctgg gtctcttttt
    34861 gcttcagtaa ataactggac atgtttccgt aataaagttc ttgttttccg tttccttgga
    34921 atactaataa cttatctgct accttgtcca agaaataacg gtcatgggaa acagtgatca
    34981 cagcacctgg aaaacttcta aaataatctt ccaaaatcgt caatgttgct atgtccaaat
    35041 cattggtcgg ttcatccaat aataaaacat taggttgctg gatcagcagt ttcaacaaaa
    35101 ataaccggcg tttttctccg cctgaaagtt tgcctatcag tgtcccatgc ataaatcttg
    35161 gaaataaaaa tcgttcaagt aattctgcta ctccgatttg actgccatct gctgtttttg
    35221 cttcttcagc agcttcttgt aagtaagcaa tcatccgttt atctggtgcc atttcttcat
    35281 tttcttgtgt ataatacgca agatgaaccg tttcaccgat agacattgta ccgctatcca
    35341 ggggaattct gccagctaga atattaagca atgtcgattt tcccgcacca tttttaccag
    35401 taatacctag tctttcccga gattgaatca gtaaatctaa atgttctagc agtgtttggt
    35461 catttatacg gtaactgcca tctttgattt ccagtacttt tttccctaaa cgttgtgtcg
    35521 ctaggttcag ctctaaatca tcttcttggt ttacttggta caagttctcc tttagatctt
    35581 cgaaacggtt gatccgtgct tgctgcttgg tgccacgtgc ctgtacgcca gccctcatcc
    35641 aagctaattc ctgtttataa agccgcttgc gcttttcttc ttgttctact tctacacgat
    35701 cacgttctgc tttttctaag acgtaagctt cataatttcc tttatactcg tataattttc
    35761 caaatgaaag ttcgaagatt cggtttgcta ctctatctag aaaataacga tcgtgggtaa
    35821 ccatcaatag tgcgccacgg tattgtttca aatagttttc caaccactcg atcgcttcat
    35881 aatctaaatg gtttgttggt tcgtctagta atagtaaatc gggttcatca atcaacactt
    35941 gcgccagact aactcgtttt ttctgaccac ctgataaagt actgattttt ttatctaatt
    36001 cactgattcc taatttttgc aaaataatct ttgcgttggt atctgtagtc caagcatctt
    36061 ctttattcat ttgttcttct gctttagcat aacgtttttg cacatcaggg tcttctccgt
    36121 tttcccctag ttcgatcaat gcttcctcat atgctcgaac agtttggatc aaggggctgt
    36181 ttccttgaaa gactgcttgg agaacagtta attcatcgga aaattcagct gcttgagaaa
    36241 gataaccaat acggtaatca gttggataaa acactgtttg ccgatcaccg tcgccgctat
    36301 cgataccggc aataatattt aagagacttg ttttacccgt cccgttcgtc ccaatcaacc
    36361 cgatacggtc tttttcgtgg accaaaaaag aaatctggtc aaacaaatct ttttcaccat
    36421 aagttttttt gaggtcagtt acttttaatt ctttcaacat gttccctcct tatcttggat
    36481 attgtatcat aaaaatagtg aacttcagga aaattttttt ggtatttgtt ctttttgtgt
    36541 tctcaaaaaa agaacaggac cgattcgatc ctgttctgat atgttttgtt ttttataaaa
    36601 cttgaaaatt tttacctttt tattttattg gactcgtttt tttgactttg ctcgaaacgc
    36661 aaatcggaaa gaaaagttat cagatggttt gttcatcgta taagattcta acaaattgat
    36721 attcctgcga tagctgttcg cagaaaacgt cgtgattttc tcagcaactt cgtattcatc
    36781 aatgattttt ctttcaagat aataacctct tagcattttt tttgtaaaca gactatcttg
    36841 ctggatcatc cacgaagaaa tcaaattccc cgagttcatt tttattcctt caagtttgcg
    36901 ttgctggata aaaaattgaa ccatcgtttc atcataaata tcagtcaagt tatctaaact
    36961 ttcaataatc aactgagtat ttttttgata tgtctctctg atttcttgga tatcttcatc
    37021 actaataaat gtctgacgat cagcatgtct tctttgccaa aacattttcg gatggagaac
    37081 gattcgcatt aacctacgga caacaatgaa ccaaaagccg ataaaagaca aaatctggct
    37141 tgtgatagaa tgttcgaatc gagaaagaaa acgggagtaa aaacgataac cattagaaga
    37201 aagcttgccc gaacgataac tttcatccaa tccatcccgt tcgatcgaca aaatcagtgc
    37261 ttgtatttct tgtacttctt gcttttcatc atcggttaaa tcttccaagt acagatcacg
    37321 tatccgttct tgataatttt ctatcactgc ttcagtggct aaaaattctt ttgtattacg
    37381 atcaatttcc tttatttctt ttcgcaaaac ttcaacgacc tcttctaaaa tcatcaaagc
    37441 attcaaatcc gtgcttttcg cttcctctgt ttccgtcagc ataggcaaga caatgatccc
    37501 tatgaccaaa gtcactaaga tgacacccgc cgtcagaaac aaaagcaaag accgctggta
    37561 aaacatcata ttattgattg aaaatggcaa aataaaaatc gtagccaaac tgactgttcc
    37621 ctttacaccg ccaaatgtta agatcaagat ctcgttcaac tgttttttga actttttact
    37681 gccatctttg aatacataaa aaagactgat agaaatgaat ctgatcacaa aaagcatgac
    37741 agagattaat acgataatcg ctaataaaag accgtttgga tataaaccgt ctccccatac
    37801 tggcgagaac acttgcgtca attcgattcc taaaaatata aatactaatg cattcagtgt
    37861 aaaagcaata gttgtccatg tactgtggga caagctcgac aattctgcat caaacacaga
    37921 gattttccta aaaccagaag cttggagaat acctgctgcc actgcagcaa tgattccaga
    37981 tacatcaaat gcctctgcca atacataggc tagaaaagga agcaaaagtt cgatcagcag
    38041 ataccctgtg acatcttgtg ctgatgcttt ttcgatcaaa tgaattattt tttgtttgaa
    38101 ccagacaagc aaaaagccga tcaaagctcc cccaatacta gaaactacta gactcatccc
    38161 cgcgtttact gctgaaaaag atccggtgat cagcgcacca agagcaaact ggaaggcagt
    38221 aacaccagat gcatcattca aaagaccttc tccttccaaa atatgcatcg cctttttagg
    38281 gatattcact cgtccagaaa gagaactgac tgctaccgca tctgtcggac ctaacgctgc
    38341 tccaaaagca aagcaggcag caagtgggac acttggcaac aggaatgata acgtcgcacc
    38401 taccccgaca agggtcaaaa tgactcctcc aaatgccaag aacaaaattg tcccgaaatt
    38461 tttgagaatc gaagaaatat ctgctttttc tccttctcta aataacaatg gtgcaataat
    38521 cataactaag aacaattcag gttcaaaatc gattgattgt ccccactctg tcagacctaa
    38581 taccactcca aggaaaattt ggatcagtgg agctggaatc attggcaaaa tgcggctagc
    38641 tatgttcgat aaggtgatcg ttactgcaaa tacaataact aactcagcaa attccatcgt
    38701 ccatcccctt tattttttat tttgtgtaag catttttaaa aattgttctt ttttctttaa
    38761 aattttggtt tcgactactt caacctgtgt ttggttaccc tctaattcac actgtacacg
    38821 ttttgactcc aaacgaagca gatcatgttt cagacgttcc aactgacgat acatcaatat
    38881 atttctttta cgcaacttac aaagtatttg acggcggtca tccatcgaaa gggcgccata
    38941 gcgatcatgc aacagttttt tttgttgttc aaaactctct ctcattttcc agatctccta
    39001 tacacaaact tccatcatta tagcaaagtt ctttttggat gaaaaatatt tcattgtttc
    39061 atcgtttatt gctagttaga aatttccata aatttttcaa cgcctcattc tattccaaat
    39121 agtatcagat atcaagtaaa acttaagaaa gataaaagtt tctgacaaaa gaatgtttac
    39181 ttttccattc ctgcctttct tgttctttta tcacaacaaa aaaatggggc tgcgacaaaa
    39241 atcttgtcac agtcccttat tctgaataaa cggtgtggaa gagacagcct atcagtagta
    39301 ataagacaca tctctttcac agcttcattt ttgcgtaaaa atcgatttat tcgaaaaatt
    39361 ccccgtatac atcttctaca cgttgatctg gattgatcac gatatacaag ttacctgttt
    39421 tttcgctgat ttttgttgat tgatattgat tgtctaatcc ttctgttcct ttatctagat
    39481 atgggaagta cacaagatca ggtgtgccat ttcggtaaag gatttccatt cgctcgatat
    39541 cttcgtattt caatgcgcga ttaaacatgc ccatttccag tccgcctagg ttgatatcat
    39601 gtgtcgcaac tgcgtcccct tcatggaaga tttcgatttt aaatccagca cacggatgga
    39661 tttcaacaaa ttcactgcca ttgattcgtc caaaacttgt tgtgatttgt ttgatccaaa
    39721 gatcgccgat atgacggcgg ttgatcgtcc aggtttctcc atttctaaaa taaaatttta
    39781 gcgctgtcat ttctttactc attaaaaaga ctcctttatg atgtaattta ttcttgtact
    39841 acctcagttt agcacaaatt tatgtaagtg gtcacatctt atgttttttc ttctaatgac
    39901 gtatctgccc actttaagta gccaacaaag ctgagcagat acagtctagt gttttttaaa
    39961 tcaatttttc tttcgataaa aaatccaaaa cctgtttttt atcatttttt attctttgtt
    40021 ctacgacggc tttttcagct aattgcaaag cttcactaac ccacttacca ggtttttttc
    40081 cagtttcttc tagcaagatt ttaccatcta ctgctaattc gcttaatgac ttgataggta
    40141 aacgatcata ggattctcct acggcatcca tctgaggtgt ttcgtcaaaa tagatcatca
    40201 attcttctac ttgcagtgca tgttttttgc ctaagaagta caattcgaat ggttccaaag
    40261 ctccagtttc tcgttgtcgt agtccttgga caagtgcttg aacgtcttta atcatttggt
    40321 tagaacactt ccacgatttc aaaaaggaac gaatctcatt ttcttttaga cccagttggc
    40381 tgatcaataa tgtccatact tggctctctt ctttcaatgg gacggatggt aattcagcaa
    40441 aacgtaaaag tgcttcgcct tcttctttca aactgggaca gcaaatgtag cactctgttt
    40501 caataaatgc atggattccc gcggcccgtt catttcccaa gagcatcttg atgaattcca
    40561 catttatacg ttctacagat attttaccta atagctcgtg gttttctttg atggcgtaga
    40621 aggtttcttc ctctaatttg aaccctagtt gactgacaaa acgcaacccg cgcatcattc
    40681 gtaaggcatc ttcatggaac cgctcatgag gattgcctac agctcgcaag atctgttctt
    40741 ctaaatcttg cagaccatcg aacaaatcga tgatttctcc atcttctttc aaagcaaacg
    40801 cattgatcgt aaaatctctt cttttcaaat cttctgccaa cgaacgaacg aattcgacat
    40861 gatctggtct gcggtagtcc tgataagttg attccgtccg aaatgtggtg atctcatatt
    40921 gttcatcatt ttctaatacc aacacagttc catgttcgat cccaatatct atcgtttttg
    40981 gaaaaagctg tttgatttct tctggaaatg cgcttgttgc gatatccaca tcatggattg
    41041 gctggttcag caagatatca cgtacacttc cacctacaaa ataagcttca tatcctgcat
    41101 tctctaattt tttcagaact ggaattgcct tttggtattc cagaggtaat tgttttaatt
    41161 tcatttttcc aacctttcct gcgtgtttct tgtactgaga taaagactca gttgcatggt
    41221 gactgtttga caagtccgtt tcagagtctt caaggccaga accacttcat cttgtttact
    41281 cgtccttacg ctcaaagcga ttatggtctc tttgattgaa tttttccatg tttttttcaa
    41341 aaacttcagt taagtcgata ttcaatgaat tagccatgat catcgtaacg aataaaacat
    41401 caccaagttc ttctgctacc gagttaactg gttcagaagc ctttttgctt ttttctccat
    41461 aagtgtggtt gacttctctt gccaattcac ctacttcttc agttaatcga gccatctgag
    41521 ctaatggaga gaaatacccc accttgaatt gctggatata ttcatccact tcctgctgca
    41581 tactgtataa agaacgcttt ttatccatct ttttccctcc aaaactatct taccaaaact
    41641 ttaacgcaaa tcctagataa gagcagttga gaaaatcgaa tttccatgct acatttagaa
    41701 aggaatttct aaatggaaat tctgtgaaaa tacataattg aaagctggaa ttcatatggt
    41761 caaacgaaaa acagtaaaag aagttctttt tatcattata ggaacaagta tttatgcatt
    41821 tggtcttgtt tacttgaaca tcgctaatca tttagcagaa gggggcgtct cagggatcac
    41881 cttgatctta agagctttat tcggaattga tccagcttat acgactttat taatcaacat
    41941 cccattgatt ttactaggag gaaagatcct cggtaaacgt tccttggcct atacagttct
    42001 aggtacactt tctttgtcat tctttttatg gatctggcaa agggttccac tagaaatcaa
    42061 tttacagcat gatctactga tcgtttctct acttgcgggt ttagttgcag gtgtaggaag
    42121 cgggatcgtc taccgcatgg gtggaacaac aggtggcagc gatattattg ctcggatttt
    42181 agaacaaaat tacggcatca ctatggggcg ttccctattg gcatttgata tcatcgtctt
    42241 acttgcttca ttaacctata tcgacttgaa acgtatgatg tatacgttga ttgtttcgta
    42301 tgttttcagt cgtgtgattg attcgatctt agatggcgga tattctgcaa aaggtctact
    42361 tgtcgtctcc aacaaaagcg aagagattgc accactactg atgaccggtc tgcaaagagg
    42421 tgtgactttt ctttctggag aaggcgcatt ctctggtaat tcaaaaaaaa tcatctatat
    42481 ggtcgttagc tctagtgaat taactgaagc taagaggatc gtccacgaga ttgacgaaaa
    42541 agctttcctt tcaatcatca atgtgcatga agtggaaggg caaggcttta cttatttgaa
    42601 gccacagaca agattactga aaaaactata agaaaaaaga caaagatagg ctatgaggaa
    42661 agattccaca tccagctgat ctttgtcttt tttagtacta tactattttt aactaattgt
    42721 tatgttcact tacccggtta cttttctttt gtgtctgcaa aaggatcttt cggttaactt
    42781 catcagataa tttcaaaaaa gcatccctat ctccatcttc tagtgcttga tcgatttgag
    42841 cataaagcat ttttagtttt gcctcttctt ctttttcttg aaaatatcgt tcaattaatt
    42901 cagtatcttc ttcactgact gaagaatccc aagaagaaaa tggattgtct tctaagatag
    42961 atagatattc tcttgtctgc caagcatttt cgaatataca ttccacatat aaaggctttt
    43021 tccaattcaa acggatttca tgaaaaatct ggtctgtgtc cgtaaattct tttccctgca
    43081 aaaacaattt catgggttcc ccttcaacag atagatcact gatctgcagt cctcgatccg
    43141 caaaattcgc cccttcaaca aagtggacat tgcttaaaat cgcttcatga ttggcaagat
    43201 aattcaagat ccaaaaaact tctcttcggc taaaagatac atgattgacc atccacgtta
    43261 aaaaattctt cttttcccgt acatcaatta gcatttttct cacctctctg ttaggtcatc
    43321 taataatgac agtgcctcca tatctcctgg ttcaagtgtt aaataataag tcaataattc
    43381 ttgcgctctt ttcagctgcc cttcttctct taagaaaaag gcatactctt tcaagaaatc
    43441 tggttcatgt gatagttcat gataagcctg ttcatagtgt acagctgcaa cggtaaagtc
    43501 ttctaattca ttataagcat gggctaggtt ccattctgca taaggattag cagtttcttc
    43561 catctgattg atcacttgta tcacatcttc atatctttca tcatccaagt aaagattgct
    43621 taaagtaagt aatgtttcat cttgtttgtc tcctacttct aaagctttca gtaaaagttc
    43681 ttctgctcgc tgtctatcat gcagacggaa agcattttcc gaggccaggt gataaagttc
    43741 gacttggtaa ggattttctt tgattccttc ttctaacact gtttgtgctt cttcaatcat
    43801 ttcttcttct tgaagagctt gtcctagata tagatataac gattgataat gcggattaac
    43861 ttctcgaagt tcttccagat agttgattgc ctgctgattt tctttcaatt gaagattcgt
    43921 aaaagctagc tggaacagtc gatcatctgt cctttcttct ttcagtgctt cttctaaagg
    43981 tgcgatagct gcttcgaatt ctccttgcat acttaaggat tgtcctaaac gttcctgcat
    44041 cgagattcct gaaatttcat ttatcccgct tgccaacaat gtttcataaa ccactgctgc
    44101 ctctttgaaa cgatcaactg aaaaatacaa ttcagctagc gcaaactgga tcaatggttc
    44161 atcaggaagc aacccagctg cttctttcaa ttttgcttca ctcacttcag ggattccgat
    44221 aacttggtac aaatcagcta tcgccaataa gctttgcgga tagtaatcac tttgcttatc
    44281 cactttttcc aggtattcaa aagctaagtc gatctcatta tcttcgattg caatttctgc
    44341 taacgggatg ttcagtccgt cattttctgg gtattggttg atcagttgtt caaaaatctg
    44401 ttttgcttcg atcaaaaagc caatagccag caattcttcg cctagttcag ctaatatatc
    44461 tgctgggtct tcttttaatg ctttttctaa aaagatttgt gcttgtgaca agtcttcatc
    44521 tgataaagct tgcaacattt tttcgctatt tgtattcatt tcaattccct cttatctcac
    44581 tgacgatttg ttgaaatacc gtcattgttc tcaataattc tttttcgttt ggacgttggt
    44641 atccgtctat tatacctatt ttttctaaaa caagtatttt tttgcttttt tctgccaaaa
    44701 aaagaacttt ttccaaatac tccatctttg aaatctgttc cagccagtgg attggatagc
    44761 caagcaagtc cagccacaca aaaaagtttt ttagttggaa atcaaaagga tatgcttgga
    44821 gattccacac gaaatgaaac atcattccta aaaatttttt catactagca gaaagtagat
    44881 ggccattttc ggtcagataa aaagcttgtt caaacagttt accataattt gacaggtttt
    44941 ctgcctctaa ttgataaaaa tagatcattt cttcgatcat cccggcaaac ggccgagtcg
    45001 ttaattgctt tttatttgga tagtttttat acagattttg caaaaaacga tgatcacaaa
    45061 tcattccgca acagataaaa gtcaaaaagt caatctgctt tccgtccact tgccgctcgc
    45121 tgattgtttg atcataaacg atgcgttctg gcagattgat ggtttgcagt actacacgat
    45181 ttggtagctg caaaatcgtc cgctgcggtg ttaatgctcg gcttagagaa cggatcgata
    45241 cagggatcat ccatagtgat gaatcaaggg ttgtatgttt ttgaaaaaaa cctgccagat
    45301 ccatgatccc ttcatttcca aatccgatga taaacatgga ttgattttcg ggatagcgtt
    45361 tgacgaaatc aagcaggttc tttaattctg ttaaatgatt gcattgagtg ttggcacaaa
    45421 tataccagtc attgtttgct tgatttgcaa ataacgggtt gatcttatct gcaaacaaat
    45481 cataatagcg ctgattcgtt aaaaataaga ttggctgatc aatggaaagt tctcttagct
    45541 ggctgactag cgtttctccg taaaacactt tcgtcaacgc atcttctact tgataatcaa
    45601 gttccatacg catccctcct cttcttattt ttattttacc attagtaagc aaattctaga
    45661 aaagataaga gcaaagctca cctcataact tggaaataaa taaaaattaa ataaaataca
    45721 tgtgttttct atgtatgaca tacggattcg gaatctctgt ctcttattta ttccttttct
    45781 gctaggaaat aaaaagaaaa gcacttgtag ccctagagcc acaagcgctt tttcaactgt
    45841 cttatttaac agcgtctttt aatgctttac ctggtttgaa tgcaggtact ttgctagctg
    45901 gaatttcgat ttcttcacca gtttgtgggt tgcgaccttt gcgagctgcg cgttcgcgaa
    45961 cttcaaagtt accaaaaccg attaattgaa ctttttcgcc gttagctaaa gcatcttgaa
    46021 tagttgaaaa tacagcatct actgctgcag ttgcatcttt tttagttaaa tcagtagctg
    46081 aagcaacttt ttcgattaat tctgctttgt ttgccatgga tagattcacc tcctccacaa
    46141 gagatatgat agaaatatca tttagttaaa actttctgag tggtccagaa gtttaaaaag
    46201 aaatattgat taacttcaat attctgttat cacgatatca tatgaaccgc ttaatagcaa
    46261 ggtttttacc aattttcaca tacttttttt agtcatagaa acgtaacaaa cgaaactgtc
    46321 tttttctttt gaaaaaaaaa cgtcgatatg gtaaaatgcc tattttctcc tacgagggat
    46381 aattcggatg gacgtccctt caaaagtaaa tgcttttctg atttgatttt ctaagaaacg
    46441 ttcataagaa aaatgcatca attcctcttc attgacaaaa acgacaaatg taggtggttt
    46501 gacagcgact tgtgtagcat aaaaaatctt caggcgtttt cctttatctg ttggtgttgg
    46561 attgattgct acagcatcca taatgatatc attcaacaca gccgaagaga tacgaagatt
    46621 ctggttcata cttacttgtt cgatcatttc aggcagacgt tccaaccgtt gtttagtcac
    46681 tgcagaaaca aaaacgattg gagcgtaatc aagataccgg aattcatcac gaatctcttg
    46741 ttcgaaatca cgcattgtat tggtttcttt ctttacaaga tcccatttat tcacgacgat
    46801 aataattcca cgaccagctt catgggcgta acccgctact cgcttgtctt gttcccgaat
    46861 cccttcttca gcattcagta ccatcaaaac gatatcagaa cggtcaatgg cacgcattgc
    46921 acgcatcacg ctgtattttt cagtattttc gtatactttt ccgcgtttac gcataccagc
    46981 tgtatcgatc attaagaatt tctgaccact ttcagaaacg aagtgggtgt cgattgcgtc
    47041 tcgggtcgtt ccttcaatat ccgaaacaat tacacgttct tctcctaaaa tcgcattgat
    47101 caaagaggat ttaccaacat ttgggcgacc aatcaaacta aacttaatcg tgtcgtcgtc
    47161 ctcttcttca gtctcttcag agaaatactt cactgcttca tctaaaatat caccaatccc
    47221 tagtccatgg cttcctgaaa caggataagg atcgcctagc cctaaggaat aaaattcata
    47281 gatatcgttt ctcatttctg gattatctac tttattgact gctaaaatca ctggtttatt
    47341 acttctgtat aaaattttcg caaccatctc atctgcgtct gtcacgcctt cgcgtccgct
    47401 gactacacaa atgattacat ctgcttcttc aatcgcgatt tctgcttgat gcttgatctg
    47461 atccataaag ggttcatcgc caagatcaat tccgcctgtg tcgatcacgc tgaattctcg
    47521 acctaaccat tcaccttttg cataaatacg atcacgagtt actccaggag tatcttcgac
    47581 aatcgagata cgctcaccag cgatgcggtt aaaaatcgta gacttaccga cgttcgggcg
    47641 gccaacgatt gcaattgttg gatttgccat attatttcct cctcacaagt ttccaatctc
    47701 acttagttta acgaatgcat tgccaacttt caagcataga ttgtcaatta aacgaagtat
    47761 ttttattcct tattgaaata ctaatcgctt ttcaaaagaa aaactgagac aaaagcagct
    47821 gctttcatct cagtcacaga tacaaaatca attatttttc agaatcatcg gttgcttttt
    47881 cttctacttc ttctttcaac gcatcaccta aaatgtctcc catagtaaat ccagtatttt
    47941 cttctggtaa ttcataagac tcaacatttt ttggttcttc ttctgaagct ggtttttctt
    48001 ctaaagcttt gatactcaat gcaatacgat gttcttctgg atggatctct aatactttca
    48061 ctttcacttc gtcaccttca tgaagcactt catgtggtgt cgcaatatgt ttatgtgaaa
    48121 tttgagagat atggactagc ccttctactc cagggaacac ttcaacaaag gcaccgaagc
    48181 ttgtcaaacg tttaactgtt ccgtctaata ctgtgccaac tggagctttt gtatcgattt
    48241 ctgaccaagg tccaggctgt gtgtctttga tggacaagga aacacgttct tgttcaggat
    48301 tgatagacaa cactttgaca tttacatcat cattgacagc caatacatca cttggttttg
    48361 ctacatgact atgtgaaatc tctgagacat ggactagacc gtcaattccg cctaggtcga
    48421 caaatgcgcc aaaatcagta agacgtgcaa cacgtccact gagaacatct ccctcatgga
    48481 tagttgaaag aatttctttt ttcttttctt ctctttcgtt ttccactacc gctttatgcg
    48541 ataagatcaa acgattttct gatggttcga tttcgatgat tttaaagctc aatgttttgc
    48601 ctttatagtc tgaaaagtct gcaacaaaat gatcttccac cattgatgca gggacaaaac
    48661 cacgtacacc gacgtcaacg actaaaccgc ctttgacaac atttgtaaca ggtgcttcga
    48721 tcaccttgcc ctcttggaaa tctctttcga tatcttccca aactttttta gcatctaaac
    48781 ggcgttttga aagtaggtag ctgccgtttt ctttatcttt gccgatcgta ctgataacga
    48841 ctaagtctaa tacatcaccg acttttacta cttcgctgat atcttctacc ggcaaagttg
    48901 ataattcttt tgccggaacg actccttcaa ctccagcccc ttcgattccg acaatcactt
    48961 gtttgtcttc aatgactaaa acttcgccct taacaacatc gccaactttt acttcttgta
    49021 cgcttttcat tgcgtcttcc attgactggt tgttctcttg attttgatca aattctgtca
    49081 taacacttgt cctcctaacc aacattctgc cgtaagtacg gtactgtttt tagtttaatt
    49141 gattattcaa aaaaaataaa gcgatttcgt tcgttttcct tgaaaaaaca attgtttttc
    49201 attttttttc ttaatttaaa aaagaagata accttttttc aaaacaacag cttttattgc
    49261 tgcaacgact tctggaatcg atttgccagt cgtatcgata cgaacagcat cctctgcttg
    49321 cttcagcgga gagacgtccc ttgttgaatc ataatggtct ctttcctgta tctctttcgt
    49381 cagtgtttca agatcagtcg gaattccttt ttcttggttc tctttgaaac gtctttctgc
    49441 acgctcactt acgcttgcta ctaaaaagat tttcacttct gcattcggta atacagctgt
    49501 cccgatgtct cttccgtcca tgacaacgcc accgcgttcc cctatttttc gttggatagc
    49561 aactaattct tctctgactt ttccatgtgc agagacttca gaaacagctt ttgtgacatc
    49621 tggttgacgg atttctaaag tcacatcttt tgatgctatg aatacatgct gtccatcttc
    49681 ttgttgcgaa aaagagatag gatacttttt gatcagcgaa actagccctt cttcatctga
    49741 aaaggataca ttgttcgtaa tagctaaata agttactgcg cgatacatgg caccggtatc
    49801 tgtataaata taattcaatt cttttgctaa tatcttggca acggtacttt tcccagatga
    49861 agcaggcccg tcgattgcaa tactgatttg tgtcatgata taactccttt ttctcaaaaa
    49921 aaagccgcaa agcgcggcta ttattattta attcttaatt cttgaccagg gtaaagcata
    49981 aagttgtttg gatctaagcc attcaattca aacaattgat cagtggtgat ccctgcacgc
    50041 tcagccactt gttttggacc ttcgcctgct tgaacagtcg ttgttgaacc ggctgcagct
    50101 gatgaagaag gtgttgtttc tgctgcattg ctgcttgaat cccctgcttg ataagttgcc
    50161 tcacttgagg aagtcggtgt tgtctctgct gcaatactgc tttctgacgt tacacctgta
    50221 tcttgagaca cagtagattc ttccgcgatt gtactagatt ctactgttga agtctcagtt
    50281 gactcctctt ttgttgtact tgtagaactt tctactactg atgtcgaagt ttcagaagaa
    50341 gttgctgctg ttgcattgtt gcttgatcca tttctgatcc agaaataagc acctgctgga
    50401 atagcgatac ataagaccag taaaatcaaa aatagcgaaa gaaataatgt atttcctttc
    50461 ttttgttgtc tctgagaact tcttgatgaa acttcatcat ctgtatcgta gattggttgt
    50521 tcccatggtt cttgtgtttc gttattttct gtagattgat gtctatcttt tctgctcact
    50581 gttttacctc ctaaactcta tcgtgtgtat tataccatag gaaaaagtgt cttgtcctaa
    50641 aaaatcaatg ttccatgttt tttttaaata aatttagtaa aatcgtttcc caatgaagtt
    50701 gttcagtctt agaaaaaagc ttcctctttg gcagaagttc tgcttttgct ccatcaatat
    50761 cacaacaatt ctgcggcttt tcggagagtt tttcgccaaa ataagctaag atgaattttc
    50821 tgcggcagtt ttcttcatta atatagcgaa gcatctgctg caggcggaat tctttttctt
    50881 tttcctgatg tttgagccgt tccacccaat tttctggttt ttcagactgc tggatcagct
    50941 ccatccattt tttttgcagc tcatcaaagg gagcttgctc tgtggcatat tccaaataaa
    51001 gctcaaaact ttgtcgctgt tctctagaaa gttgattaaa gaaataatgg atacgttcat
    51061 ccccactttg ataaaaaaga attgctgcac tttcttcctg atctctgcct gctcgaccga
    51121 tttcttgtac atagttttct agactgtctg gcaaatcata atggatcaca taacggatat
    51181 cagatttatc gatccccata ccaaatgcat tcgtagcaat gagaaactgc agctgatttt
    51241 ttacaaactg ctgttgaagt tgtcttcttt gagctgcatc aagaccaccg tgatagtatc
    51301 caactgtaaa acgttccctg aataaatgat acaatcgttc gacttctttt tttgttgcac
    51361 aataaatgat tgccgctcct tgtgctcttt ccatgaagtg ttcaagttct tgttcttttt
    51421 gctgcgtttt ccgaacaaaa agcgagatat tttgccgatt gactgattgt ctgatctctt
    51481 ttggtggtcg atcaaatagt acatgacgta tatctcttgc tactaaatct gttgctgtcg
    51541 ccgttagtgc cagtgtgacc gggtttccta aaagctttcg gatttttcct aactgttgat
    51601 attctggacg gaaatcaact ccccattgag acacgcaatg agcctcatct actacatata
    51661 acgcaatatt ttgttttttc agatgctcta aaagagaagg attagtcaac atttcgggac
    51721 tcaaaaacaa aaatttatat tgcgatagat gacggaggac gtatcttctt tcagattgcg
    51781 aaagtaaact attgaaagca gctactcgtt tctcccctcg tttttgtaat tgcgtcactt
    51841 gatcttccat tagagaaagc agcggtgaca cgatgatgac cagaccttcc attaaaaacc
    51901 ccgtcaattg atagcaaagg ctttttcccg ttcctgtagg caaaatagcg agagtatctt
    51961 ctccatcaag caacgcctga atgatttctt cttggccggg acgaaatgaa tcaaatccaa
    52021 aatatttttt taattcattt attaacattc tgtatcgctt cctttctcaa tagatagatt
    52081 tgatacaaac gaaattctcc ataatctaat tgtccatcta cattccattc gctaaagcgc
    52141 cactctcgca cggaatcctt atttggttcc aaacgttcga ttgtttctgc agagagaatc
    52201 cgctcgtatg gaaaatcatc aaaaaacaag gcccactcaa taagatgatc tgttactgtt
    52261 cctcttttta aatgacggat tgccataatc tggtcaattg tctgaccatt cataaacatc
    52321 tgcttggtga tcatcatgct ttgattgaaa ttttgctgta ataatgaatc gatcaaagcg
    52381 tgccaaagcg aatctggccg tttttcgatt tgtgctaaca aaaggtggat acatctgctt
    52441 tgttgcagat aaaccgctga ctcatcattg ttttttgcca gctgataagg aagcagccct
    52501 gttcgctcat ttccagataa ttggttagct aaaaaatctg ctgcttcttc tggtatctcc
    52561 gaaaacagct gcaccaaact ctcatacgca gtatcaatca aaatttcacg tggcaattgg
    52621 ctttcactaa gccatttttt tagttggaaa gtataaaaag gacttgtctc tgctggaaga
    52681 tagtcttgaa tacccgttgc cagattagaa attacttgaa cagcaaattt aatgagccgc
    52741 caactagttt cccctgttct gccatagcgg tcaaaacgca aaccagtatg ttctatttga
    52801 tgttcggaca acatatcagc ccctgcaggc gttagctttg cttcattttc atttatttcg
    52861 atccaacctt gctgcgcaat tttttgcaaa atttgataaa acttatcctg cttcaattct
    52921 ggaaaactgt tatggataaa caaaagttcg tgggtaaatc cataaataag tactgaagtc
    52981 gttcgttttc ccacaaggag ttggtaaaga gaactaatcc gcagcttgtg tcctgatgaa
    53041 aatagcgata aaataaaaac aatcatatta ttctccttaa gttaggatgg ttagaaatgt
    53101 cactactatg taaacttgta cctgaacgct gtattgcatg cggtctttgt caaatcgaag
    53161 cgccagatat tttcgattat gatgaagaag gaatcgtttt atttgcccaa gaaccagagg
    53221 ctcatcaaca gttcgtgatg ccggaagaag aaacatatgt aaaaaaagcg tatcaaaaat
    53281 gtccagttcg agcgatttta ttagaaaata aaatataaat ataaacgaaa ctttaaaaac
    53341 gtacactaag ttctctaaac ttgaaaataa gccgggatct gtttctcttg ttccgtgaaa
    53401 tcccgactta ttttgaaaga ttcatttgct atctatagtt aattgactag ttttttcacg
    53461 gaccctatag gacccattta tattatttca actttttcag ccagttttcc aatgtattga
    53521 cgatcacagt ttgctggtct gcgttagaaa tttctgcctc tccatctcct ttttgctcac
    53581 catagctgcc aaaacctcca tgatttccgc cattgattga tacatactct gttctttccg
    53641 gtaaatactg cttagcttct tgataagctt cctgattcaa tactttatct tttgtcgccg
    53701 tgatcgataa aacaggaaca gctgattctg tcaatgttcc ttttttgtcg ggataacttg
    53761 ccatgaagaa tacccctttt aaatgtttgt ctgaatgatt cttattgaca taacgacttg
    53821 ccattacgcc acctaatgaa tggccaccga tcacataatc ggaatttgga aaatcttctt
    53881 tgaccttatc cgctttgttt ccgcccatca ctgctagatc aagtggcatt ttgacaatag
    53941 cgactgaaaa gccgtttttt gctaaatctt gcgcccaaat actataactt tctggctcta
    54001 cgagagcacc aggataaaaa ataagtaatg gagaatttcc atgattcttt ttctctcctt
    54061 caaaaaataa gtaatcttct ttgttttttc cttcttttac caacacttgc gcttctgacg
    54121 atggttcgta cgtattttgc tgtatatagt aataaccggc tccaccgagt aatcctaaaa
    54181 tgatgactaa gccaattagt attcgtctaa atattttcac tttctcccac cttttctatc
    54241 tgagtgaccc ctttttctta atcaagtatg attatacctt aaaaaaaata agagagaaat
    54301 gcaaactttc cagcatcaaa taaaaaaaga cggaatatcc atttgaatat ccgccctttt
    54361 tgtatgttta tttttattta gcacataaac gatacacagc ttctgcataa atttccattg
    54421 ctttatacat actacttaat tcccatcgtt cattcgcctg gtgcataaag tcaggagtat
    54481 cagggaacat cgcaccgaat gccacacact ggttcatcgt acgagcaaaa gtagcgccgc
    54541 ctgatacaaa cggttcagtc atgtctccag taatatcgcg atatgtcccc aatagatttt
    54601 tcactaactc actgtctagt ggcacgtata atgaatcaag gaagtcaaat tcttcataag
    54661 tcaacccata tttttctgct gttttagtta atttagctac taaatcatct ttcttgaatg
    54721 taacagggat tctcatatct acaccgattt ttgtttgttc tggtgtgatt tccaaacttg
    54781 caaagttcat cgttagctcg ccggattgtt catcttctgt tttgcccacg acagcttcac
    54841 cagttgcatt ttcttgaact aattttccta agaaattgat tgggccaaaa tcgaatactt
    54901 ctgaaagagc aattgccaga cgagaaatag cattcactcc ttgtgctgca tctttcgcgt
    54961 ggatactttt accaagaacg acgatgcctt caccttgttc ttcgaaatcg aattcgtgtt
    55021 ttttcaacgc ttcttttact tcagaaagct tttctccaga gtaaggagct gcatcaggaa
    55081 caacattcaa cgctcctcca gcttttacag aaaactcgtt cgttcctggt cctgtcaagt
    55141 aagcttgcaa taagcctttt tctgcataaa ttaaaggaaa ttcagcatct ggcgcaaatc
    55201 cttgcgtaat tccttcttct ttttcgttat atttttctaa acaacgccat aaattttctt
    55261 catctgtacc aaagataaaa cgaatacgtg tcttgaattc cacgccagca tcaatcaaag
    55321 ctttgacggc atacattgcc gcaatagaag gacctttgtc atcttgggat ccgcgaccaa
    55381 ctaaccagcc gtcttttata gttggatcga atggttttgt ttcccaatta ttttcgtccc
    55441 ctgctggaac aacgtccata tgacacaaga taccgaataa ttcatctcca gagccaatct
    55501 ctgaataacc gtaatagcct tctggatctt taaatgttct aaatcctagc ttttcactga
    55561 tttccaatac tttatccaaa gcttcaatca cttttttacc gaagggatgt ccttgtcctg
    55621 aatctgcttc atctagtacg gaaggaattc ggatcaattc gctcaatgat tctaatgctt
    55681 gttcatgatg ttgttctgtc acaaattttt tcatgatatt atcctcctaa tatgttaaaa
    55741 agggtcatgt caaattcctc cgacacaacc tcttcttctc aaataatgac gttttaagcc
    55801 tgctccatca gcaagcagaa tgttcttaac aaatgatgaa agaaaaaaca ctcactgaat
    55861 ggagctattg acttgtccac gtgcttatcg atagccgttt atcggtttct tcattcttat
    55921 gatagacctt gtacctgtat ttgtctaggt ttagaacatt gctgctacac ctaggatcac
    55981 acagatggct acaaataata tcgcaattaa tttaccggta aatttccacc acactgaaac
    56041 atcgaaacga gcaattgcta cagcacccat tacgatagca gatgttggtg taattaagtt
    56101 tactaaacca gatgcagatt gataagcagt gattactaaa tccttaccga cgccggcaaa
    56161 ttcacccata ggtcccatga ttcccattgt tgcagcagct aagccggaag ttgaaggaat
    56221 caagaatgac atagggatat agaaaataaa tgtaataatg atgaatacac ttgaagataa
    56281 tgaacttaat ccttgttcgc cccaatgtaa gatggtgtct gtgattaatc cattgttcat
    56341 aaccacttgg ataccacgag caacagctac tacgattgct acaccgatca aatcagaagc
    56401 accagctaaa aattcagaga caaattcaga ctctttcatg ccataagtga ttgctactac
    56461 gatggacatt actaagaata acatagtaat ttctgggaag taccagtcac ctaatggaag
    56521 catgctttta cctagaacag tacctagtac cggaaggttt gttaaccagt ttgtcaatga
    56581 ttcaaaaatc gtgaaattcg cattcaaggt tgtccaagga atcaaactga tgatcatgat
    56641 accaaaagta ataaagaaca atacattaac atgtttttgt tttttcgtga ttacttcttg
    56701 acgaccgatt gcttcaatat cgaaatgctt catatcttct ttacgttggt tgtatactaa
    56761 tgattttgtt ggatcttttt cgatctttga tgcataacga tacacatata caatagaaat
    56821 agctaacaaa ataacgaaca tcaagaatcg aagaccaata ccttcaccca tcgaaatccc
    56881 aacagcttgt gaagctacgc ctgttgcaaa aggatttacc gttgaagcta gacagcctac
    56941 ttgagaccct actaatacga ttgctactgc tactactgta tcaaagccta cagccatcat
    57001 aactgggatc agtaaagcat agaatggaat cgtttcttct gccattccgt aagtagagcc
    57061 gcctaatgca aataacagca tcaatactgg aataagcatt ttttcttttc ctttgaattt
    57121 cttcacaact gaagcaatcc cggcatctag tgcccctgtt ttgttgataa tacctaaaaa
    57181 tccaccaaca accaaaatga agaaagagat tgggattgca gcaggtgttt ctttagttag
    57241 ctcccccgct ggtacaccta acatcccatt gattggcgcc atgaaaatat cccacagccc
    57301 ttgaggattt tgttgtactc gttcatatga tccagcgacg atgttgcctg catcgtctac
    57361 actatagtgc ccagctggta taaaccaagt aagtacagcg attactgcaa taataataaa
    57421 taagaccgta tacgctgaag gcatttgaaa ttttttcttt tttgtttgtt ccatcttctt
    57481 cttcctttct tttccgttag agacaacaat tttggctcta atgttatttt atcaaaaaga
    57541 gtatcagaac aaaaataata acacgcattt tgtaaaactt ttgttcaaaa agttcgtttt
    57601 tccctattcc ctcctctttt ttcaggtttt taaagctttc ttctttttca ttgtagcgtt
    57661 tccttttttt tataaacaaa cattttcgtc ttttaaaagg agaagaattt cacatttgca
    57721 aagaattgat tgatttttat gcataaatca aaaaaatact caaaacaaac aaataaaacg
    57781 tttacattat tgcatgtctt gtattttttt ccaaaaaaaa agaccaagaa atttcttgat
    57841 ctttttgata attatttgac tgctgtatga cgttgttcga actgatgttg ttttcgactt
    57901 aaccatggaa gaagttgcgc atgcagcact aaaaagacag cgctcacgat gaatcctttg
    57961 atcaagttga aaggaacgat cccaatcagt acatagtttg ctaaagacat gcctagcatc
    58021 tgtgttgcgt tcagtcctaa aaacattaag taaagaggcg taataacgaa ataatttgcg
    58081 atactcataa aaatagttag agcgatggtt cctgtaatga cacctaaaaa tttgtttctt
    58141 cctttatgct gtttctttac actaaagaaa taataaatcg ggaatgtaaa gatcgttgtt
    58201 gataagaaac tagcagtgtc tcctaccaaa ttatccggag aaaaacctgt agtcagcaga
    58261 tgtaatactg aacgcaagaa cgctgttgca actccggccg ctggaccgaa taagaacatg
    58321 ctgatcaata ccgggatatc actaaaatcg atcttcaaaa aactaaaagc cggcatgatc
    58381 ggaaaagcaa aatactgtaa aactaacgcg atcgcagcaa acatcgctac tgcaaccatt
    58441 ttctgtacac gggtgttctt catttgaaat cctcctgtta ggactcctct tcagcgaact
    58501 ttttgacgtt tctctccaaa tgaaaaaact ctattttcca gggaaaatag agttagagtt
    58561 atttgatcaa gcgtcgtcaa ataagctcta tcttctttat ccagactata ctgtcggtat
    58621 cggaatttca ccgattcagc tattttttgc aaaataggtc gtggactata accaccggtc
    58681 gggaatttca ccctgcccct gaagacgaac cttatataat ttttgtttac atattcatta
    58741 tacatatcta ttcaaaaaac gcaacatcta acacttataa aaagtaagtg ttcattttga
    58801 gtggttcagc aaactgctga cttctttttt gttcagttca cggtaatctc caggacgtag
    58861 gccttgtaaa gtcagatctc cgtatttttc acgttttagt ttttgcacag gaagaccaac
    58921 tgcttgaagc atatttttca cttgatgatt acgtccttcg tggatcgtca attccacgat
    58981 actgtggttt gtcttaggat ccactgataa aatttggaat ttagctggag atgtttttcg
    59041 tccttcgatc tttattcctt ttgtcaaagg tgcaagcatc gattttgtag cgatcccttt
    59101 tacctttgca acgtaaactt tatccacttc atgttttgga tgtgtcaggc gctgagcaaa
    59161 atctccatca tttgtcagta gcaagatccc cgaagtatcg taatccagtc gacctacagg
    59221 atagatacgt tcttttacca tcggcaaaag atccgtaaca acttttcttc ctttgtcatc
    59281 tgcaacagca gaaataactc ctttaggttt gtacaataaa taataaccgt attcttcttg
    59341 ataaattggg acttcatcca cttccacagt gtcatgtttc ccaactttta tccctaattc
    59401 ccttacaact tgtccgttta cttttacacg tcctgcaagg atgaattctt ctgcttttcg
    59461 acgagaagtg atgccagcgt gggcaattac tttctgcaat ctttccatta caattattct
    59521 cctttattca ttccatcaaa gaatagatct ggtgacacgt cttcttcaaa tgaaatttcc
    59581 atttcttgtg tatcaggcag ttcttctaat gatttcaaac caaaataatc taagaagtag
    59641 ccagttgttc catataatat cggccgacct ggcccttcta ctctaccttt ttcttcaatc
    59701 agtttatggg cagctagacg ctgtaccgct cctgaaacct gaactcctcg aatctgctcg
    59761 atttcagctc ttgtgattgg ctgtttataa gcgatgattg ctaaggtttc gacagcggct
    59821 tgagataatg tgtttgatgt cccttgcgca tatcgcttaa gtaagggagc cagctctttt
    59881 ttagtcgtta atacataatg gctttccgtt tcaaaaatat gcaaagctga gtgcgagttt
    59941 tgagtgtaag attcttttaa ttctttcact aaacttgtga cttctgcttc gctgagattt
    60001 aacagtccgc ttaattcttc attactgatc ccttcctcgc caacaataaa aagaagggct
    60061 tcaagttcac ttaatttcgt catgttcggt atctcctact gctggataaa gcataattga
    60121 ttcatagttt tctttttgtt gcgcaatgat ctgccctttt ttcatcaatt ctagcaaagc
    60181 cataaaagta gtgacaactt cacttttaga aggtgactca aaaaaagaat cgaaagtaca
    60241 gccatgcgca tttcttttta tacgctcttc gataaatacc attcgttctt cgatcgttgt
    60301 gtcatcgggc gtgatcgttt tttccacttt ttgagaaaat ttcttacgtt ctaagatttt
    60361 ctgcatggca cggatcaaat cgattttttt gacttgtcct cgcttcaacg gcttttcagc
    60421 atccgctaac ccatcgatgt tcataggttc ttttgtgtaa taaagacttc gttcctctgc
    60481 tttttctgtc agtctttcag ctgcatattt atatttacgg tattctaaaa gctgagtgac
    60541 caattcttct cgaggatctt cttcccataa ttcttcatca tctgtgacga attcttggac
    60601 aggaagcaat gtcttgcttt tgattgccat caatgtagca gccatcacta agtattctcc
    60661 tgcaacagct agctctagtg ttttcattgt atggatataa ttcatatatt gctccgtgat
    60721 cgtagcgatc ggtatatcat atatatcgat ttccatttgc tgaatcagat gaagcagcag
    60781 atcgagagga ccttcgaata catctaattt aatattgatc tccgtcaact cattcactct
    60841 ttcttctttt tctttgctag ccattttcca atgtaaggct ctgtgatttc agttgcacgg
    60901 atggagacat ccgggtactt ttcctgtaat tcatctaaca tttgaaagcc catattctca
    60961 ccgcgataag acggattcaa agaaatgtca tggatgatca gctgatcgtt cgttgcccag
    61021 taaacaccaa taatcccttg aatgttggtt gaaccttctg gcgtaaagaa aaaaagttca
    61081 taatcgtctt cagattcgta cgtatcaatc tccttcaaca aagaagtttt acctgtcagt
    61141 ttcttatgga aactcaatag tcccatagca attttacggt tttctttccg gtaatgtgtt
    61201 aacatcttct caccttccta tgactaagcc cttggaaaat gctgcttata aacatccgtc
    61261 attcttttct tcgtgatatg tgtataaatc tgagtcgtag agatatccgc gtgacctaac
    61321 aattcctgta ctgtccgcaa atcagctcca ttttctagca gatgtgtggc aaagctatgc
    61381 cgcagcgtat gtggtgttac ttctttgtaa atcccagcct ctcgtactag ctgcttcaga
    61441 tttttccaga ttccttgccg agaaagacct ttcccatgat tattgacaaa tacatgcatt
    61501 tcagatgcgt cctttacaag taatggacgt gcttcgtcta agtagcgttc cagccattgg
    61561 atcgcataat cacctaaagg aatgatccgc tctttatctc cttttccaac tgtctgtacc
    61621 agtccaagag aaagatgaag atctcccaat ttcaatccaa tcaattcact gacgcgcatc
    61681 cctgtagcat acatgacttc caagattgca cgatctctta tccctaacgt ttttgtcgta
    61741 tcaggtgctt caatcagctt ttctacttct gtcagagtca atgtacttgg taatttctgt
    61801 gctttcttcg gcgtatcgat atgttgcatc ggatcatgat cagtgatacg ctcttgccgt
    61861 aaaaactgat ggaatcttct gagacttgag atcatccgag taacagttgc tgtcgctttt
    61921 ttttcttcat gcaacttctc cagaaaacgg atgactaaaa agcgatcgac atcctgccat
    61981 gaagcaattt tctgctcctg tagaaaatgc aagtactgtt ccaaatcacg ttcatagctt
    62041 tgtcgtgtat tggcggacaa tccccgttca atattcaagt agtggagata atcgttgatt
    62101 tgctctttca taataatccc cctcatgcct ctctatcata tcagataccg cttcattctg
    62161 atagtctttt tccataatct gagcaaagaa aaagccgtct agacactcag acggactggt
    62221 ttcttttttc tttttcatag cattcctgac agattccatg gaacgttagc cgatgatctt
    62281 ttactaaaaa atgataacgt tcttctacta cttgctccac ttcaagtaaa agatcctctt
    62341 ctacttcctc gatcgtgccg cagttcaagc atagtaaatg atgatggaaa tgtttggcgc
    62401 cttcttttct caaatcataa cgggctaatc catcattaaa acttacttta tcgacaattt
    62461 tcaattctgt caagatttca agggttcgat aaacagtagc aagtccaatt tccggactct
    62521 tttttttcac taaaaagaag atttcttctg cagataaatg ctctttctca ttttccaaaa
    62581 gcacaagcag agtagcttct ctttgcggtg tcagcttaaa ccccgcttca tgtagctgct
    62641 gttttgtttt tttcatcgcc gaaatagcat tcatgaccat ttactcaacc ccaacaattt
    62701 ataataatta caaataaaaa aagatataac actatgttaa ttaaaattat tataagctag
    62761 ttaagaaaaa catgcaaggg attctcaatt agattttttg actagttttg tcacaccgtt
    62821 ttcttgtgta atcaatcctt gtttcaaaag attacctaat gcgcgcttaa atgctccttt
    62881 gctgatacca aaagctttca tgatttcttc tggatccgat ttatctgtaa agttgatttg
    62941 ctgatctgca gaacgttcta aaatggttaa aatcatttgt gcatcatctg atatagcttc
    63001 atatgctctt ggcttcaatg aaagattcag tacaccgtct ggtcggacac caatcactcg
    63061 accttttatt tgctcgccta gacgaggttc attatatcgt tcagaaggat ggataaaccc
    63121 aagatagaaa tcttccgtta aaacgtacgt acctgttaat ttcaagcggt atgctgttcc
    63181 tatcacatct ttgtttttca tttcttctgt tccatatttg cttaaagatt tgaatatttt
    63241 ttcatctgct aaactgcccc aaatacggtc ttttgcatca actctaaggg aaatcatcaa
    63301 gcgatcccct tttttaggcc atagctctgt cattgtcggc aattcatcaa gagatacgac
    63361 aaagtcttta tctggaagac cgatatcgac aaacgcacct aaatcttttc gtgtagcagt
    63421 aacgattcca aaagcgtaat gaccgatacg gcttttagga atttgtgtag tgatccgatt
    63481 ttcatgtttt tgattttggt agccgaatcc ttccactgct tcaccgattt tgtgttcacc
    63541 ttctgatttg cttaagccaa aggtttgtcc gtttttttgg acaaagtagt ttttttcatt
    63601 ttcatcaata ataatacctg taaatatagt tgctaataaa tcgttcattt ttttctccct
    63661 ctatagtgaa aggttttctt aatacatttc tttgctatca taacataatg ttatctactt
    63721 gaatagctga gccttggttt ggaaaggtga aaaaaggagt atgacaacag ttgtgtcata
    63781 ctcccctttt tcgaataaac ggtgttaaac ggcaggctca cagcctcttt catttgccta
    63841 aaattaattg ctcccatttc ctccgaacca tccagtttta cagttgatgg ttacgatgta
    63901 aaatggcaaa gcactttctc caatgccttt catcaatgca gattttgttg aagtggcata
    63961 tagattgtaa tagccttccc cattttcgat tctggctttt tctaatctgt atcctccttc
    64021 aacgatatat ccacgttgga tacatgtagc aatcactttg ctttggacac ctggtgccca
    64081 cgtccatgct ggattagatg catcggcaat atcacttgct ctggcagatt tgattggctg
    64141 attcgctgag tttgaagagg aaggggtcga ggatgccgct tcttgctgtg ctgcttgtgc
    64201 gaccgcagct tgttgagcgg cttgagctgc agctgctgct tgagcggctt gttttgcttg
    64261 ttcttcagct gcttttttcg ctttttctgc ttttttcgct tcttctgctt ttttcttttc
    64321 ctcttcttct tttttctctt tatcagtgag catcttatct acttgttgca attgttcatt
    64381 caactgagca gatagatctg tatttttcac tttttctact gcttcttttg ccgtcttgta
    64441 ttggtcgcgt gttgctgaat ccactacttt tccgtcttta aagactatag ctgttttttc
    64501 tttagctgtt tgcaattcag catattgatt tttagcttct gtttgtgctt gttgaatcaa
    64561 ttttccaaaa tctgtgttat ccgtttcgat tgcttggatc tctttatctg ctttcaactt
    64621 gatgtcatct gctagatgat catcgacgat ggcaggtgct atgaaccact cattcacttt
    64681 ttggatatct cggatcttag attggatatc ttggtaagtt gtttctaact ctgaatatcc
    64741 tttttcattc ttaagactgg ataaatcatt ttttagtttt gataaatctt gatgaatcat
    64801 atctgcacga ataaattgat ggtgatcatc tgtataaaag gcagcaagtt tctcatgaag
    64861 ttcttccatt tgttgctgtc tttttgcttc tgctgctact tcggcttcta ctttttgatg
    64921 atggtcataa taagcccagc ctcccccacc tagtagaaga actgctgcta aagcgagata
    64981 cggcactttt tttgattttt tcttttgtgt cttatctaaa tctttttttt ctgggtttga
    65041 ttcttgaggc gttttttcag tatttggcac gattgttatt ggttctgttt ctgcttcaat
    65101 cagctcaggc tggttctctt ctttttctat tttagcttca agagcagtgc tatcttcact
    65161 tgcagattga gtttcagcat cggcttcatt atttattcca tccgactctg ttgccttctt
    65221 gtctgctttt tcgagcattt cttttttatc tgcttccggc aacccattcg atttctcgtc
    65281 ttctgattgt ttttcagaca atgtttcagt tttttccggg atatccgttt ttagatcatt
    65341 cgtttttaga tcattcgttt ttaatgattc tttacctgca gcgtttactc cactaatgtc
    65401 tttttcagtg tctttttcag cttcatgttc tggctctact ttgttttcct gtgcaatttt
    65461 ttcactgatc attttgagca gctctttcgc gtgctcttct tttgtatctt cacgatgtgc
    65521 tttgatataa gcggatagta tcgaattttc ttcctcatta tcgacgattt ctttcagttc
    65581 agctactctt cttttttgtt ttgattcaag cgtttcttct tgattctttc ctgattcttc
    65641 cgaagtctca tgaacagttg ctttcttctg ttcatttttc tctatattag ttacttgatc
    65701 gtgagcaggt ggttcttcgt cttctggttc tgctttttcg aataattcca ttacagattc
    65761 tagaggtaaa tctttcaatt ccgaccattc gattggatcg tttaattctg tatcaggaaa
    65821 gactgcatct tcagttgatt tatcctgcat agctgcatct gtatttgttt cttcaattga
    65881 ttcttttatt tgctgatctt ctgcagttat ttgatgaccg cagtctggac agatagtatt
    65941 ctgctccatt tttttcgatc cgcaatttgg acattttttc atcacttagc gatcggctcc
    66001 tttactaggt ttacgctacc atttaatcta tcatattcta tacgtcacgc caatagctta
    66061 tttttaggat ttacttaaaa ataatgaatg aatttccttc ctatagaaaa aaaagcttga
    66121 gactgcgtag tctcaagctt tttttctttt aaaataaacc aaacagtttt actgatttct
    66181 cttctggtca atagttcatg cttattctaa gaaatctttt aattgttttg aacgagaagg
    66241 atggcgcaat tttcttaatg ctttagcctc gatctgacga atacgttccc gagtaacacc
    66301 aaatactttc cctacttctt ccaatgttct cgtccggcca tcatctaaac caaaacgtaa
    66361 gcgaaggaca ttttcctccc ggtcagtcaa tgtatctagt acatcttcca attgttcttt
    66421 tagtaactca taagctgcgt gttctgctgg acttgttgct tcctgatctt ctatgaaatc
    66481 acctaagtga gagtcatctt cttcaccgat tggcgtttca agtgaaacag gttcttgcgc
    66541 gattttcaag atttctcgga ctttttctgt tggaagatcc atttccgcac cgatttcttc
    66601 tggcgtaggt tctcttccaa ggtcttgcag caattgacgt tggatacgta tcaatttatt
    66661 aattgtttca accatatgaa ctggaatacg gatcgtacgt gcttggtcag cgattgctcg
    66721 agtgatggct tgacgaatcc accatgtagc ataggttgaa aacttaaatc ctttgcggta
    66781 gtcaaatttt tcaactgcct tcatcagtcc catgtttcct tcttggatca agtcaaggaa
    66841 ctgcatgcct cgtcctacat aacgtttagc gatacttact actaaacgaa ggtttgcttc
    66901 tgccagacgc tgtttcgctt cttggtcgcc ttcttcgatt ttcaatgcta acgctacttc
    66961 ttcttccgca gttaaaaggg agacacggcc aatttctttc agatacatac gaaccgggtc
    67021 attgattttt acaccggttg gcgcagatag atcttctgtt tttgcttgtt cagctttttt
    67081 ctcagcactc ttcaagctgt gaattgatgg atcaccattt tcatccacca cactgatacc
    67141 tgcgtcttca atcttttgga tcaatttgtc catttcatct gcattcaaag tgaatggtgt
    67201 agcaagctga ttggataaat catcatatac aacttgtcgt ttgggtttgt tttctttgat
    67261 gaaagctgct actgctgctt catacgtttt tttatctgtt ccatttgcca taaaagaagg
    67321 ccccccttga gtagctattt ggcttgtttt aactgtttcg ttaaattgat gatttcaatc
    67381 gtcaattcaa gctcaagctg tttgtttcca gttcgtctgg cttcttgctg catttgtttt
    67441 tttaatgtta tttcatcagc taagccagat ttgctgatca catctagcaa gtcttggatt
    67501 tctcgtggcg aactttcttc tgccaccggt aaatattcga tttccaccac caaccgcctt
    67561 aaattttcat cttgcaaaaa gtctaaaaac tctgcaaggt tgaattcata atgttgtgag
    67621 acatatgcat cgaataaaaa ataaacttct gcatatgcat catgaataaa ctgaaattct
    67681 cgttctttta aaatattacg gacagaaact tctttaaatg cacgatataa tagaatctgc
    67741 tctgcctttt ctacttgcgt caaaggtctc tttttccgtg cagtttcttg tctcgtaacc
    67801 tgagtgtgtt gactttcctg aggttcttga cgattttgct gatttgtcct tcgaagatcg
    67861 cgcagttgtt tttgtatcgt ctctctgccg atctgaaact ctgttgacag ttgagataga
    67921 tacatatctt gttcgattgg tgaaacaact cggctaagtt caactagtaa ttcttcgagg
    67981 tattcgatct tgtctttttc attatctaaa tttttccctt gttttaaata acgtgattta
    68041 aaagtaaaga ctgtttcgcg cccatgagcc actaattctt ggaaagatgc ttctccatac
    68101 ttacggagat attcatcagg atcaagcttt tctggaacga ctacgacaga aagtgctaag
    68161 cgactgtttt gccgaagcaa ttcaatccct cgattggttg cttcaaaacc tgcgttgtct
    68221 ccgtcatagc aaaagaccaa ttctttcgtc agcttttcca tttgttggat ctgttgagct
    68281 gttagacttg tccccataga agctaatcca gttttgatac cagcctgcca tgcagcaatc
    68341 acatccataa acccttcgaa caacaaaatt tctccgtttt tccggatatc gcttcttgct
    68401 ttatcaagat taaataaaac ttgtctttta ttgaacagtt ctgtttctgg actattcaag
    68461 tatttgggct gatctttttc ctgccctttt tcaggtgcaa gccagcgtcc tgaaaaaccg
    68521 atcgtctggc cttgagaatt acgaagtgga aacatcactc tttgataaaa acgatcagac
    68581 atacggccat catcatgcgt gacaaacaat ccagagcgtt ctaacaattc atttgaaatt
    68641 gattcattct tgaatacttg ctgaagaaaa gaacgctcat taggtgcaaa acctatgttg
    68701 aattcttcaa ttaattctaa agacaaccca cgactttgca aatattctaa agctggctgt
    68761 ccagcttttg tatgcaatag catgtgatga tagatttccg ctgctttttc atgagcagca
    68821 atcagtttcc ccgtagcaga ttcaggattt tggacagcta tagtacgctg acgccattga
    68881 tcttctaacg gtatctgttc gaagtctgcc acttttacca ctgcttctgg aaaacttaga
    68941 ccttctagtt cttgaagaaa agtaaacacg tttccgccct taccacaacc aaagcaatga
    69001 aaaatctgct tgtcttctgc aacagaaaaa gacggtgtac gttcttcatg aaaaggacac
    69061 agccccaagt aatttttacc agactttttc aactggacat attgtccaat cacctcaacg
    69121 atattcgttt gactgcgtac tgtttcgata acctcttgag gaatccgttg agccattttt
    69181 ccaccccctg ctctattgat atcttttggg tttaacagaa gatatttcag gagaataacc
    69241 ggtaaaaaat cgcactaact gaaatcagtg cgattttaaa ggacacaatt atacatgttt
    69301 gattgtatca tatttcattg ctttttcaag tataacacat ttctatctca ttaagcatca
    69361 atttgctact cttttcagta actgattttg aatatcagcc ttccagtaca atactcgaag
    69421 aacaatattt acgagcatga atacaaagaa gtatcctacg ctctctccca accctaagtt
    69481 tacttccaaa attccatgga acagcattgc agctacatat atccctacga tcgtcgttac
    69541 tgctaggaag atgcgcaatg ggttgaaggg ataacaagct tttacaactg ccatgcaact
    69601 gatcccaatc agcaagtaat acatcaaagt agtagtttca gcatttcccc atgcgaatgt
    69661 ttttccaagt agatacaccg caatgatatt cactactaca agcaaggcat ttggtaaagc
    69721 attaataagt gctgtaggca aataacggta agtgattttt cttttatctt gttcaaaaga
    69781 taaaaagaag gaaggatacc cttcaatcgc taaatcaatc agcgtgattt ggatagggat
    69841 aaacggaaat ccaattgctg taacggcaca tataatcgat aaaataaatg aataaatcgt
    69901 tttgataaaa aagatgcctg agactttcgt cacattgttg accactcggc gtccttcaaa
    69961 caggacttct ggcaatgtag taaaatcaga gtccaacaat accagattcg caatctgacg
    70021 tgttgctcca tcaccttctg ccatagcaat gctacaatct gcttctctta acgccaaaac
    70081 atcattcaca ccgtcgcctg tcattgcaac cgttctgccg ctttctttca attcatttac
    70141 cagcaatttc ttttgctgag gactcactcg tccaaaaacc gtatagcgat gagcagcttc
    70201 tcgcacttcc atttcttcag taatttgaga aagatcgaca tacgcatcat aattcggtaa
    70261 tcctgcacgt ctagcgatat tggagacagt aaaaggattg tctccagaaa tcactttcag
    70321 atccacacct tcctcatgaa gataagctag tgtttcttga gcgttttttc ggattggatc
    70381 atcgatttca aacagagcaa ccggctcaac aaatgctggt ttttcttcgt tcaattgctg
    70441 atttggagcg atccctaaca taagtacgcg atagccattc gcttgggctg tttttagact
    70501 gtccggaagc cgatcttctt ccaccaaacg ttcaggcgct cctacgtaca cgactcccag
    70561 ttctggaaat tccatcgcgc cccatttgcg atcagaagaa aatgcgactt tgtttgtcac
    70621 atcataccga ttagaaagct caaaataatc tctcatagcc cgcatagtga tgttgttatc
    70681 actgctttct gccagatacg tccccataat ttctgggatg gctttctcgt acagcggatg
    70741 tagtgcttct acccgctgga tactcatttt tccttcagta atggtccctg ttttatccaa
    70801 gcataatgta tcgacatggg ccagcgtttc aattgaatac atgtcttgaa caaggattcg
    70861 tttttttgcc agtttggtta cccctgtcgt taatgcaata cttattagca ataccaaacc
    70921 ctttggaagc atgcctaaca aagctgctgc agatgcaata acagaaattt tgatagaagc
    70981 atcgcggatg aacagtgctt ccaaaaatag tatgatcccc aaaggaataa tcacgaaact
    71041 agtgaatttg gatactttgc gaatcgaatc tacaagttca gaacgaatag ctttgtgagt
    71101 ctttgcctcg ctagtcaagc ggacagcata attatctgca cctactcgga taacttcagc
    71161 catgacagaa ccgcttgtca aaaagcttcc agaaagcaat tcagctccag tttctttgac
    71221 aatcaaatca gattcgcctg tcaaaagagc ttcatttgct tctgcccgtc cagatataac
    71281 ctgtaaatcg gctggtatct gttctcctgc tccgattttt accaaatctc ctaataccag
    71341 ctctttagta gaaatcgatt gttctttacc gtcccggatc actagtactt ctgattggga
    71401 aacaatcgat aatttccgta caagatttct tgcatgtatt tcttgataaa ttccaataac
    71461 gatattgacg acaataattg ctaaatacgc catgttggaa tacgcaccta caaataacag
    71521 acaaatccca ataccaaagt tcagaaaatt gaataacgtc aatatattat cgctgaatat
    71581 ttgttttgta ctttttgatg catcttcctg gtagtcattt tgctggccag aagccatttt
    71641 ctgaactacc tcttgctgtg taagtccatt cattttcttt ttctccattt tccgccaact
    71701 ttcaaaaata atcacgtgtt taagtctagc gtgttccaag attaaaaaca acttgttttt
    71761 ataaaattta tagaaaaaca cacgaatgat tttacaaaaa agatgccaac ctttttgttt
    71821 gaatcacccg tgtgctgttt ttattatcaa tctatcttta cttatattgt tcctccaaac
    71881 ggctcatcca ccaacctagt gctgtaccgg ctataaaaag aacaggacaa gctagtaccc
    71941 cagcaactcc caatcccgcg taatcggtag gaatgatcat aatcgttgaa gcaaaaacta
    72001 cacctaaaat gaaatggaat agcttgctat atgcctttga gaaaatgtaa tccatgattt
    72061 ttgacaatcc aagaacacaa agaatcccac caattccgat cggcacaatc acttcaagtc
    72121 gtacttcttt aaatccgtca gccatcgctt tatacaatcc catatacacc aaaaaattag
    72181 aagggctcaa tcctgggacg atcataccca aaccaatcaa tccgccggca atcagccatg
    72241 ttccaaaatt ctgatcgact tgcccgtcaa ataattgagc gccgtataat aaaaacaaat
    72301 aagccagaac aaaagtaaca accatgatga tcacatcaga agtatctctt ccttttttcc
    72361 ctgcttcttt ccataacgca ggaacagttc cagcgataca tccgacaaaa aaccataata
    72421 tcgttgtttc atacgcacct aataaaaaac tgactaaaaa agaaagtaga aagatgcctg
    72481 tcactccgcc tagaccaaca ggcagaaaaa acaaaacatt ttctttgaaa ttttttgtaa
    72541 ggtgggctaa aaaagaaatc agccgctcat acatgccaaa gacagctgct aatgcaccac
    72601 cgctgactcc tggcaagata aatcctgaac cgataaacat tcccttcaca aaccgtaaca
    72661 tccagtcttt ggttgtgtac cccacttttt gattttccat tttttgcctt ttttccacta
    72721 tttgcgcact ccttctttca tttaatttta ttcatgattg aacatttcct gctattttac
    72781 ttaaaaactt tttcataggt ctctattatt ttttcattca ttttgacaat atcaggataa
    72841 aacatgttac ctccattatg atagagatag ccgccattgt aaagcaagga ctggatccgc
    72901 caatatcggt attgtttccc ttcctcattt cctaaaagtg ggctcagcac atctttagaa
    72961 tacgcttctg ctaattctac tgtgttttct ccgccatgat tttttacata ggcaatataa
    73021 tctttcccaa aattatatgc ttggacagct gtccataaat cgcatccttg tttctttgct
    73081 tctactatca tttccgccaa atatttgaca ccttgatcaa tactgtcagc tggattatca
    73141 atgatctcag cttctccatg cagactttcc gagctccgca tgagatctgt cccttttcct
    73201 tttgattcgg tcaatattat cgccttgatc aaattctcgt agttttccat atgataattt
    73261 tttgcagctg ttgttatttc tatttgatag ctttccactc gttttaccga acgataagtt
    73321 cttcctccta aaaacaacac cgcaccaata accgtcagaa tgatcatgta aaaaagaata
    73381 cggataatag ataatcgttt tcgcttcatt tcatcaccta gttattttga catctttttt
    73441 tatcttacta tttctttatc ttcttggcta tttcttcctt gatttctgtg tacgccttaa
    73501 gaaaaaatga attttcctgt attttttgtc atcttacgaa aatgatcgtt gtttttcagt
    73561 aaaaacaatt gcccaatgac tgatataatc gttatacttt acacagtagg tgattatgtg
    73621 aaaaaagaaa agaaatatgc aaaaatgcca gatgggagcg aaatttacta tgaaaagagc
    73681 ggtcaaggct tccctctctt tttactgcat ggcaatgacg gcagcggccg ctttttttca
    73741 gaacaggtcc ctgtactcga acgctactat accgtgtatc tagtagatag ccgaggacat
    73801 ggtcgttcga caaacgaagc atctatgttg aattttcagt taatggccga ggatctgaat
    73861 acgatcatgt tgctggaaaa aatcgatcag gcagattttc ttggatttag tgatggagca
    73921 aatctagcac tggtatttgc cagcagcttc cctaaaaaag ttcatcgatt gattttaaat
    73981 tctggaaaca cgcttgttaa aggcgttcgt ttttctgcca gagtcatcag taatattcat
    74041 tatgcatggg tatggttact ctctttattt cgcccaagtc ttcgcaaaaa tcttttagtt
    74101 atcaaacttt tgctgcatga catcgggctt acagaaaatg atttaaaaaa aatcaactcc
    74161 cccactttga tcatcgtggg aaaaaaagat gtaatcaagc taaaacattc tttgtatata
    74221 gctaaaacta taccaaaagc ttcctttgtg cttgtgaaag aacaaggaca tgaattagct
    74281 agaaaagatc ctgaacgctt caatcgagaa gttcttcaat ttctttctga aacataacta
    74341 ttaggaatag aaggtgattt atttgttaaa aaataccata caatggctga aaaaccacct
    74401 aggactgttc aaaacaatct ttttgatttc tgtcattgtc attattgtcg gtgaattgat
    74461 gtccatcggt aaaactctat ctatccagca attaggagaa acgtttgcca ctatacctgt
    74521 atggaaaagc ggacttatgc tgttgattgg tcttgtctct gtgttaccta tgattggtta
    74581 tgatattatt ttgaatcgga tgcttgaaca aaagcagaat cctcgttact tgtttgagac
    74641 aagctggctg atcaatacaa tcaacaatat tgccggtttc ggcgggtttg ttagtgtggg
    74701 gcttcgctct gaactatatg gacaaaagaa agagagcaga aacgtgatcc aagcattatc
    74761 gaaagttttc ttgtttttga tggctggact ttctatttac agtctgcttt cttttttact
    74821 tgtagtcttc acgccagttg ctcctttttt gaagcaatat tggatatggt tgatcggcgg
    74881 cggtctatat tttcctgtcg tctttttatt tactactttc aaaaagaaag gattccttgg
    74941 tggtacctca cttaaaactc aaggacagct attgctagtt tcattgttgg aatggaccgg
    75001 tgtcctgttt agtttccttt ctgttggtta tttaatggaa atccggattg atctgtggca
    75061 aacaattccg ttattcattg ctgcttcagt gataggaatc gtgtctatga ttccaggaga
    75121 aattgggagt ttcgatgtaa tgatgattat cgggttgtcc gctattggtg tgccaagaga
    75181 aatagtcgtt gtgtggatct tgctctatcg cctgttctac tacatcattc cgtttttgat
    75241 tggaatcgtc tttttcttca aaaatatcgg ttccactttt gatcagcgtt attctggtat
    75301 ccctaaacaa ttagcaacag aaattgcgca taaaatcgtg gttgtcttat tatacttttc
    75361 tggaatcatg ctagtacttt ctgccactat cccgcaagct tttacagagt ttcgctggct
    75421 tcatagtttg aacccattga aatttcattt tattatccaa tttcctagta tactattggg
    75481 atttctttta atcattatgg gcagagggat cgcagcacgt gtgaaacgag catatttgcc
    75541 tacaatcttc ttgattgttc tagctttact ttatgtttta ttaagtgatt ttagtttcac
    75601 accggtggtt ttcttgtcta ttctgcttct gatcattctt gcttctaaaa acgaattatt
    75661 tcgggaacaa ttgatctatt catgggagtg gcgtacgatc gatggaatca ttattggtgc
    75721 actgtccttg ctttacatcg ttattggggt atacaatctg ccggatttcc ctcatcggcg
    75781 tcaccatttt atttcctttt tcttatttcc ttctgaaaag atttggtttt cgggattgtt
    75841 ggccatcatc gctgttagtt tcatgatcgt tctatttgtt catttccttc aaggagaaaa
    75901 gaaacagatt ggcgaagcct ttaatgaaga aaaggccctg aagatcctta caacttatgg
    75961 aggaaactcc gatagtcaat tgatcttctt aaaagataag cggatgtttg cctatgaaaa
    76021 agacggtgaa ccaactgttc ttctccaatt cgcttgcttc aataataaat gtattgtaat
    76081 gggtgatcct tctggtaaga aagaagattt tccagaagca atcgaagctt ttatcgaaga
    76141 aacagatcga ctatgctatt taccagtttt ctacgaaaca agcgaagaga ttgttatgat
    76201 tttgcatgaa ttcggctacg atttcattaa gatgggggaa gaagcttatg tagacctgaa
    76261 tagttttaca acttcaggga aaaaaatgaa gggcactcgt gctgtcttga atcggatcga
    76321 acgagaagga tttacatttg atgtcttaca accaccattt tctactgagc aaatgagtac
    76381 tttcaaaaat atctctgata attggttggg ttcacgaaag gaaaaagggt tttctttagg
    76441 ctttttctct gaagattatc tacaaagagc gcctattgca gttgtcaaaa atacccaaga
    76501 agaaattgtc gcttttgcaa cgatcatgcc tacttacacg aacaataaag taggaacgat
    76561 tgatctgatg cgatatgatc ctaaaaaagc accttctggc agtatggatt tcttgttctt
    76621 gcatttgttt gcctatatga aagaagaaca tatccaatgg ttcaatttag ggatggcccc
    76681 tctttcaaat gtcggaactt ccagaaagag ttttttacag gaaaggattg catacttggt
    76741 ttacgagttt ggttctcatt tttattcttt ccatggatta agagaatata aaagcaagta
    76801 cgctacaaac tgggtctcac gttatactct atattctaga gatagttgga ttgcatatgt
    76861 tatgattgct ttgctgatta ttgataatgc gccagttgag cagacacaag gtagaataag
    76921 tggtttgaaa aaatggatac gaagaaagta ttaaaaactg cataccgata gatgaacact
    76981 ctcatgatga ataaaagaga ctgaagtaaa acgaaagttc atgcttctac aatctcttct
    77041 tatacaattg aagaacaaag agcggtccaa acagaaatcc tgtttggacc gctcttttat
    77101 tttaaacatt tttcattacc aaaatattcg agtcgcgttt cttatgcttc gatctctgta
    77161 acgatacctg aacccactgt ccgtccgcct tcacgaattg agaatgtcgt tccgttttca
    77221 acagcgattg gatggatcaa gtcaacatca atcgtcacgt tgtcaccagg catgaccatt
    77281 tctgtatctt ctggcaatgt gattgttcct gtaacatcag ttgtgcggaa gtagaattgt
    77341 ggacgatagt tgttgaagaa tggagtatga cgtccacctt cttcttttgt caacacgtac
    77401 acttctgctt tgaattttgt atgtggagta atggaacctg gtttagcaag cacttgtcca
    77461 cgttcgatat cgtcacgttg gatcccccgt aacaacacgc ctacgttatc cccagcttcc
    77521 ccgtaatcta acgttttacg gaacatttct acacctgtta caactgcttt ttgtgtttca
    77581 ggtttgatcc ctacgatctc tacctcatca ccgacacgaa cagcaccacg atcaatacga
    77641 cctgaggcaa cagttcctcg acctgtaatt gagaagacgt cttccactgg caatagtaat
    77701 ggtttatctg tatcacgttc tggtgttggg atatattcat ctactgtatc catcaattcc
    77761 ataatagcag cttcagcatc tggatcgcct tgcaatgctt ttaatgcgga acctttgatc
    77821 acaggagtgt catcgcctgg gaaaccatat tcgctcaata actcgcgaac ttccatttct
    77881 accaaatcga tcaattcttc atcatcgact aaatcaactt tgttcaagaa aacaatcagg
    77941 tattttacac caacttggcg tgacaataaa atgtgttcac gtgtttgagg catcggaccg
    78001 tcagttgcag aaacaactaa gattgcacca tccatttgtg ctgcccctgt aatcatgttt
    78061 ttcacatagt ccgcgtgtcc tggtgcatca atatgcgcgt agtggcgttt ttctgtttca
    78121 tattctacgt gtgcggtatt gatcgtaatc ccacgttcac gttcttctgg agctgcatca
    78181 atactagcat agtcttgagg atttgctagg ccttttttgc ctaatactgt agtgatcgca
    78241 gcagttaaag tagttttccc atggtcaacg tgtccaatcg taccaatgtt aacgtgtggt
    78301 ttacttctgt cataatgttc ttttgccata atttacaaac ctcctaaata atatagatca
    78361 ctgaaaaatt tcagctctca cctttttatt atagtctttt tttgactaaa tcaaaaagaa
    78421 tacgtccgac ttactttttg taagattcga actaagctta ttatacgtca atattggtca
    78481 aagtcaacta agagcactcg cttgtcttat acgcgaaaaa agtacctttt ataaataaaa
    78541 aaatgtgttt tttgagaaaa acttcaagat agtccttaac tttcttttga agcaataaga
    78601 acaaaatgag gaaaagttta aaattcagct gttgccaaca actttcaata gacgaaatct
    78661 tctatttcgt taataataag gaaagaggtg aagtacatga aaaaattaat tggcgtactt
    78721 gtcgttttag gcatatttct cggcggaagt tttgcagctt atcattattt ttacggcggc
    78781 gaagcttatt atacaaaaat cacgacgaat ggcgaaatgt cagctaccca agcagataac
    78841 ggagagaaat tcacgactta tacctacaag caagcggctt ataataaaga tggtgaaaaa
    78901 aaacaggtga cgcttcgcga agaaagagaa catccattaa agatgaatgc gtatcttaaa
    78961 ctcaaagtca atcctcgtaa aggtgtatta agctgggaag aaataaaggc ttctgaagtg
    79021 cctaaaaatg cggcagaaaa aatcgataat tagtaaatgg tcttaaaatt ttattagata
    79081 aaaagaggct gggacagaag cgtttaactc caagaaataa gaaggagttg cttctgcttc
    79141 cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg tctcacgctc
    79201 tttttttgtt atattcgtct tttccgatcc ttctcttgac acaattcatt taactgatca
    79261 ctggtacttg aacacctaat gttctagtca tttttataaa cgattcaata cttcatccac
    79321 atttttgatc atcacggata tcgtaccatc cggattattc acaaattcaa tcaaatctgg
    79381 gttgcgatat acatctactg gtacgatcag ttcgatcccg tttgatagct tgaatttttg
    79441 ttttccaaat tttttctcag aaatttcttg tacttctttt acaggaggtg cttctgggac
    79501 aaatccttgc tcttgtactt cttctttaaa agccattttt gccgtgatgt tttccttgaa
    79561 gactttttcc gcaatcatct catgatccaa ccgacctttt tcttctatcg tatcatagac
    79621 agcttctttc aaatcagcca tgatatcaaa ttcttctgtc tcaaattttt ttccaagatg
    79681 cttggctact ttttggatca cttttacatt ttcttctaaa gaaggtgcag gaacactttc
    79741 gatcactctt ccagaaaaat aaagctcttt tttgccagaa aactcatatt ttttttcaat
    79801 taattcgtag gtccaatcag tcaaattcac agcgaatgct tcatctgctt tttgtgtttt
    79861 cgcccctaga attgctcgat tcaaaatcaa gcggttgtcg atccctgctt cgtctgcttc
    79921 aacaaagtga gtgtaagcct cacgataatt gactttcaat aaagataagt acatcactgt
    79981 atctaattca tacaaaacaa caaatacatc tgcactaggt gcttcttcac tttcttggta
    80041 gatatcgaac caccgctgaa cgattgcttc acttgcttcc acaaaatttt cttgagcgat
    80101 tttaagtgat tcaacgatca tgctttcttc tgctagttgt ccagtttttg tttgagcaga
    80161 agagattttt tggatcttct tttgaagaaa atcacgaata tattcttttg tcagatccag
    80221 ctctttttgt gaaaagactg gagaaccagt ttctctgtca ataatatgca gaattgcttt
    80281 ttttaaatag atatccattt tctcattccc ttctgtctta gtttacggaa aaaaaatcaa
    80341 aaataccaga atcaaaatca ttttctttta aacaaaaatt tcaagagtag aaacaaaatg
    80401 gattcttttt ttcgaaaaat gcgctacact tatagttgaa cgaataaaaa aggagctgaa
    80461 agtatgaatt cattaacaag cacttatcgt ctattaaatg gttacgaaat cccggtagta
    80521 ggattcggca catggcaaac acctgatggg gatgtcgctg tttcctctgt taaagaagcg
    80581 ctggctgcag gttatcgcca tatcgatact gcccaaggat acaagaatga agaaagtgtc
    80641 ggccaagcga ttaaggaaag tggaattcct agagaagaga tattcttgac aacaaaatta
    80701 tggaatgcaa accacagcta tgaacttgtg atgtcttctt ttgaagaatc attgaagaag
    80761 ctccaaacag attatttaga tctgtttttg atccactggc caaaccctgt tgcttttcgt
    80821 gataattggg aacaagcaaa tgcagataca tggcgagcat ttgaagaact gtatgaagca
    80881 ggtaaaatca aagcaatcgg tgtgagcaat ttcttacccc accatctaga tacactagca
    80941 aaaacagcaa aaattatgcc gatggtcaat caagttttcc ttgcaccagg cgaattacag
    81001 ccaactgtag ttgagtatgc aaaaaaacat gatatgatcc tcgaagcata tagtccatta
    81061 ggcactggta aaatcttcga tgtgcctgaa atgaaacaaa tcgctgaagc acatgacaag
    81121 acgattgcac aagttgcttt gcgttggtcg ctgcaacacg aattccttcc tcttcctaag
    81181 tcagtgacac caagcagaat caaagaaaat actgaattat ttgattttga attaacagaa
    81241 gaagaaatga aacaaatcga tcagttagat ggtgtagtcg gcaaagcaaa agacccagat
    81301 actacccaat tttaagtcga aaggtgattt tatggatcca atcgaacgct tgaattctct
    81361 ctcggaagaa gttacccaga cttttcattc cgattttgtc tttttgatcg atgcagagaa
    81421 aatccaacat tttcctgcaa gaaactggac acatgatcaa atcatcgaag aactgaaaaa
    81481 acggttcgat cattcgctaa tggtcaaacc ctggcacgaa catgaagtca tttattcacc
    81541 tgaactacct gtttttgcct tgataccgaa aaaatagaaa gaatg
//
LOCUS       DAZKCW010000005        73057 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000005 DAZKCW010000000
VERSION     DAZKCW010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73057
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.005"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            129..500
                     /locus_tag="ACG84Z_000337"
     CDS             129..500
                     /locus_tag="ACG84Z_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFP9161213.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(774..1466)
                     /locus_tag="ACG84Z_000338"
     CDS             complement(774..1466)
                     /locus_tag="ACG84Z_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9161214.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(1469..2254)
                     /locus_tag="ACG84Z_000339"
     CDS             complement(1469..2254)
                     /locus_tag="ACG84Z_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFP9161215.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            2491..3891
                     /gene="lacG"
                     /locus_tag="ACG84Z_000340"
     CDS             2491..3891
                     /gene="lacG"
                     /locus_tag="ACG84Z_000340"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFP9161216.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            3916..4233
                     /locus_tag="ACG84Z_000341"
     CDS             3916..4233
                     /locus_tag="ACG84Z_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFP9161217.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            4246..5919
                     /locus_tag="ACG84Z_000342"
     CDS             4246..5919
                     /locus_tag="ACG84Z_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFP9161218.1"
                     /translation="MDGIIKQIEKGKAFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            5933..7564
                     /locus_tag="ACG84Z_000343"
     CDS             5933..7564
                     /locus_tag="ACG84Z_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFP9161219.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(8055..9620)
                     /gene="guaA"
                     /locus_tag="ACG84Z_000344"
     CDS             complement(8055..9620)
                     /gene="guaA"
                     /locus_tag="ACG84Z_000344"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFP9161220.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(9679..10602)
                     /gene="coaA"
                     /locus_tag="ACG84Z_000345"
     CDS             complement(9679..10602)
                     /gene="coaA"
                     /locus_tag="ACG84Z_000345"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFP9161221.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            10798..11403
                     /locus_tag="ACG84Z_000346"
     CDS             10798..11403
                     /locus_tag="ACG84Z_000346"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9161222.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            11711..12727
                     /locus_tag="ACG84Z_000347"
     CDS             11711..12727
                     /locus_tag="ACG84Z_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9161223.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            12868..14169
                     /locus_tag="ACG84Z_000348"
     CDS             12868..14169
                     /locus_tag="ACG84Z_000348"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFP9161224.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14215..14877
                     /gene="deoC"
                     /locus_tag="ACG84Z_000349"
     CDS             14215..14877
                     /gene="deoC"
                     /locus_tag="ACG84Z_000349"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFP9161225.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            14898..15296
                     /locus_tag="ACG84Z_000350"
     CDS             14898..15296
                     /locus_tag="ACG84Z_000350"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFP9161226.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15362..16444
                     /locus_tag="ACG84Z_000351"
     CDS             15362..16444
                     /locus_tag="ACG84Z_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9161227.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            16656..18218
                     /locus_tag="ACG84Z_000352"
     CDS             16656..18218
                     /locus_tag="ACG84Z_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161228.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18211..19344
                     /locus_tag="ACG84Z_000353"
     CDS             18211..19344
                     /locus_tag="ACG84Z_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9161229.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19344..20300
                     /locus_tag="ACG84Z_000354"
     CDS             19344..20300
                     /locus_tag="ACG84Z_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9161230.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20399..21565
                     /gene="deoB"
                     /locus_tag="ACG84Z_000355"
     CDS             20399..21565
                     /gene="deoB"
                     /locus_tag="ACG84Z_000355"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFP9161231.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            21589..22407
                     /locus_tag="ACG84Z_000356"
     CDS             21589..22407
                     /locus_tag="ACG84Z_000356"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFP9161232.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22424..23131
                     /gene="deoD"
                     /locus_tag="ACG84Z_000357"
     CDS             22424..23131
                     /gene="deoD"
                     /locus_tag="ACG84Z_000357"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFP9161233.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(23429..24115)
                     /gene="gpmA"
                     /locus_tag="ACG84Z_000358"
     CDS             complement(23429..24115)
                     /gene="gpmA"
                     /locus_tag="ACG84Z_000358"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFP9161234.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(24287..24868)
                     /locus_tag="ACG84Z_000359"
     CDS             complement(24287..24868)
                     /locus_tag="ACG84Z_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9161235.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(25001..25684)
                     /gene="rpiA"
                     /locus_tag="ACG84Z_000360"
     CDS             complement(25001..25684)
                     /gene="rpiA"
                     /locus_tag="ACG84Z_000360"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFP9161236.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            26003..26416
                     /gene="rpsL"
                     /locus_tag="ACG84Z_000361"
     CDS             26003..26416
                     /gene="rpsL"
                     /locus_tag="ACG84Z_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFP9161237.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            26500..26970
                     /gene="rpsG"
                     /locus_tag="ACG84Z_000362"
     CDS             26500..26970
                     /gene="rpsG"
                     /locus_tag="ACG84Z_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFP9161238.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            27064..29151
                     /gene="fusA"
                     /locus_tag="ACG84Z_000363"
     CDS             27064..29151
                     /gene="fusA"
                     /locus_tag="ACG84Z_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFP9161239.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            29323..30510
                     /gene="tuf"
                     /locus_tag="ACG84Z_000364"
     CDS             29323..30510
                     /gene="tuf"
                     /locus_tag="ACG84Z_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFP9161240.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            30917..31225
                     /gene="rpsJ"
                     /locus_tag="ACG84Z_000365"
     CDS             30917..31225
                     /gene="rpsJ"
                     /locus_tag="ACG84Z_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFP9161241.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            31256..31885
                     /gene="rplC"
                     /locus_tag="ACG84Z_000366"
     CDS             31256..31885
                     /gene="rplC"
                     /locus_tag="ACG84Z_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFP9161242.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            31913..32536
                     /gene="rplD"
                     /locus_tag="ACG84Z_000367"
     CDS             31913..32536
                     /gene="rplD"
                     /locus_tag="ACG84Z_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFP9161243.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            32536..32826
                     /gene="rplW"
                     /locus_tag="ACG84Z_000368"
     CDS             32536..32826
                     /gene="rplW"
                     /locus_tag="ACG84Z_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFP9161244.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            32865..33698
                     /gene="rplB"
                     /locus_tag="ACG84Z_000369"
     CDS             32865..33698
                     /gene="rplB"
                     /locus_tag="ACG84Z_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFP9161245.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            33741..34019
                     /gene="rpsS"
                     /locus_tag="ACG84Z_000370"
     CDS             33741..34019
                     /gene="rpsS"
                     /locus_tag="ACG84Z_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFP9161246.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            34042..34389
                     /gene="rplV"
                     /locus_tag="ACG84Z_000371"
     CDS             34042..34389
                     /gene="rplV"
                     /locus_tag="ACG84Z_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFP9161247.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            34403..35059
                     /gene="rpsC"
                     /locus_tag="ACG84Z_000372"
     CDS             34403..35059
                     /gene="rpsC"
                     /locus_tag="ACG84Z_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFP9161248.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            35062..35496
                     /gene="rplP"
                     /locus_tag="ACG84Z_000373"
     CDS             35062..35496
                     /gene="rplP"
                     /locus_tag="ACG84Z_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFP9161249.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            35486..35674
                     /gene="rpmC"
                     /locus_tag="ACG84Z_000374"
     CDS             35486..35674
                     /gene="rpmC"
                     /locus_tag="ACG84Z_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFP9161250.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            35699..35965
                     /gene="rpsQ"
                     /locus_tag="ACG84Z_000375"
     CDS             35699..35965
                     /gene="rpsQ"
                     /locus_tag="ACG84Z_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFP9161251.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            36023..36391
                     /gene="rplN"
                     /locus_tag="ACG84Z_000376"
     CDS             36023..36391
                     /gene="rplN"
                     /locus_tag="ACG84Z_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFP9161252.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            36428..36736
                     /gene="rplX"
                     /locus_tag="ACG84Z_000377"
     CDS             36428..36736
                     /gene="rplX"
                     /locus_tag="ACG84Z_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFP9161253.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            36764..37303
                     /gene="rplE"
                     /locus_tag="ACG84Z_000378"
     CDS             36764..37303
                     /gene="rplE"
                     /locus_tag="ACG84Z_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFP9161254.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            37322..37507
                     /locus_tag="ACG84Z_000379"
     CDS             37322..37507
                     /locus_tag="ACG84Z_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFP9161255.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            37543..37941
                     /gene="rpsH"
                     /locus_tag="ACG84Z_000380"
     CDS             37543..37941
                     /gene="rpsH"
                     /locus_tag="ACG84Z_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFP9161256.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            37973..38509
                     /gene="rplF"
                     /locus_tag="ACG84Z_000381"
     CDS             37973..38509
                     /gene="rplF"
                     /locus_tag="ACG84Z_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFP9161257.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            38670..39026
                     /gene="rplR"
                     /locus_tag="ACG84Z_000382"
     CDS             38670..39026
                     /gene="rplR"
                     /locus_tag="ACG84Z_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFP9161258.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            39047..39547
                     /gene="rpsE"
                     /locus_tag="ACG84Z_000383"
     CDS             39047..39547
                     /gene="rpsE"
                     /locus_tag="ACG84Z_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFP9161259.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            39562..39741
                     /gene="rpmD"
                     /locus_tag="ACG84Z_000384"
     CDS             39562..39741
                     /gene="rpmD"
                     /locus_tag="ACG84Z_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFP9161260.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            39785..40225
                     /gene="rplO"
                     /locus_tag="ACG84Z_000385"
     CDS             39785..40225
                     /gene="rplO"
                     /locus_tag="ACG84Z_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFP9161261.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            40225..41520
                     /gene="secY"
                     /locus_tag="ACG84Z_000386"
     CDS             40225..41520
                     /gene="secY"
                     /locus_tag="ACG84Z_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFP9161262.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            41582..42229
                     /locus_tag="ACG84Z_000387"
     CDS             41582..42229
                     /locus_tag="ACG84Z_000387"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFP9161263.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            42420..42638
                     /gene="infA"
                     /locus_tag="ACG84Z_000388"
     CDS             42420..42638
                     /gene="infA"
                     /locus_tag="ACG84Z_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFP9161264.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            42671..42787
                     /gene="rpmJ"
                     /locus_tag="ACG84Z_000389"
     CDS             42671..42787
                     /gene="rpmJ"
                     /locus_tag="ACG84Z_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFP9161265.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            42805..43170
                     /gene="rpsM"
                     /locus_tag="ACG84Z_000390"
     CDS             42805..43170
                     /gene="rpsM"
                     /locus_tag="ACG84Z_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFP9161266.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            43198..43587
                     /gene="rpsK"
                     /locus_tag="ACG84Z_000391"
     CDS             43198..43587
                     /gene="rpsK"
                     /locus_tag="ACG84Z_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFP9161267.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43667..44605
                     /locus_tag="ACG84Z_000392"
     CDS             43667..44605
                     /locus_tag="ACG84Z_000392"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFP9161268.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            44633..45013
                     /gene="rplQ"
                     /locus_tag="ACG84Z_000393"
     CDS             44633..45013
                     /gene="rplQ"
                     /locus_tag="ACG84Z_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFP9161269.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            45285..46124
                     /locus_tag="ACG84Z_000394"
     CDS             45285..46124
                     /locus_tag="ACG84Z_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFP9161270.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            46100..46969
                     /locus_tag="ACG84Z_000395"
     CDS             46100..46969
                     /locus_tag="ACG84Z_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFP9161271.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            46959..47756
                     /locus_tag="ACG84Z_000396"
     CDS             46959..47756
                     /locus_tag="ACG84Z_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFP9161272.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            47959..48705
                     /gene="truA"
                     /locus_tag="ACG84Z_000397"
     CDS             47959..48705
                     /gene="truA"
                     /locus_tag="ACG84Z_000397"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFP9161273.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(49160..51829)
                     /locus_tag="ACG84Z_000398"
     CDS             complement(49160..51829)
                     /locus_tag="ACG84Z_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFP9161274.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(52067..52255)
                     /gene="rpmB"
                     /locus_tag="ACG84Z_000399"
     CDS             complement(52067..52255)
                     /gene="rpmB"
                     /locus_tag="ACG84Z_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFP9161275.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            52525..52887
                     /locus_tag="ACG84Z_000400"
     CDS             52525..52887
                     /locus_tag="ACG84Z_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFP9161276.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            52939..54621
                     /locus_tag="ACG84Z_000401"
     CDS             52939..54621
                     /locus_tag="ACG84Z_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFP9161277.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            54738..56774
                     /gene="recG"
                     /locus_tag="ACG84Z_000402"
     CDS             54738..56774
                     /gene="recG"
                     /locus_tag="ACG84Z_000402"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFP9161278.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            56823..57824
                     /gene="plsX"
                     /locus_tag="ACG84Z_000403"
     CDS             56823..57824
                     /gene="plsX"
                     /locus_tag="ACG84Z_000403"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFP9161279.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            57946..58188
                     /gene="acpP"
                     /locus_tag="ACG84Z_000404"
     CDS             57946..58188
                     /gene="acpP"
                     /locus_tag="ACG84Z_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFP9161280.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            58456..59460
                     /locus_tag="ACG84Z_000405"
     CDS             58456..59460
                     /locus_tag="ACG84Z_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161281.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            59461..60405
                     /locus_tag="ACG84Z_000406"
     CDS             59461..60405
                     /locus_tag="ACG84Z_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161282.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            60405..61367
                     /gene="opp4B"
                     /locus_tag="ACG84Z_000407"
     CDS             60405..61367
                     /gene="opp4B"
                     /locus_tag="ACG84Z_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFP9161283.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            61394..62308
                     /locus_tag="ACG84Z_000408"
     CDS             61394..62308
                     /locus_tag="ACG84Z_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9161284.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            62334..64115
                     /locus_tag="ACG84Z_000409"
     CDS             62334..64115
                     /locus_tag="ACG84Z_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9161285.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            64463..65149
                     /gene="rnc"
                     /locus_tag="ACG84Z_000410"
     CDS             64463..65149
                     /gene="rnc"
                     /locus_tag="ACG84Z_000410"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFP9161286.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            65169..68750
                     /gene="smc"
                     /locus_tag="ACG84Z_000411"
     CDS             65169..68750
                     /gene="smc"
                     /locus_tag="ACG84Z_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFP9161287.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            68759..69568
                     /locus_tag="ACG84Z_000412"
     CDS             68759..69568
                     /locus_tag="ACG84Z_000412"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9161288.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            69579..70577
                     /gene="ftsY"
                     /locus_tag="ACG84Z_000413"
     CDS             69579..70577
                     /gene="ftsY"
                     /locus_tag="ACG84Z_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFP9161289.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            70764..73031
                     /gene="gshAB"
                     /locus_tag="ACG84Z_000414"
     CDS             70764..73031
                     /gene="gshAB"
                     /locus_tag="ACG84Z_000414"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFP9161290.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
BASE COUNT        23649 a        13282 c        15980 g        20146 t
ORIGIN      
        1 gaacgggttg gtttttaata gatttaataa gtactgataa tgaaatttct cctggttggg
       61 aaaacgaagt tggttaccct gtagaagaat tttttcaaga ttactttgcg gagtatgccg
      121 ataggataat gagagattac gtaacagata aaactcaaga agtcatcaat caatcccagt
      181 cattaaatga attatctgat aaggcgaaag aagaagcagt tgccattatt tcttcaggga
      241 ttagtgacta tattgatatg agtggtgaaa tcaattatgg cgataaagac aaaattgtac
      301 gcatgataaa agcttttatc aaaacttttg atgtgaaggc agatcttaag tttaatgata
      361 cttacctagt aggaaaatta attaatatcc ttgggacaga gaaagatacg gaaacgttta
      421 tttcctcttt gtctatgttg tttacagata agcatttttc aactcagctt ggtggagagg
      481 aactagtgga aatcttttaa ccattacgcc cagcattaat aaaagtatat caaaaaagta
      541 ctcctgatga tttttaagat tggtttgaga aataatgtga aaacactatt tttaatgtta
      601 attatagata gagatgaacg cgtcatatgg ttaaaagaat gaaaaagtca aagatacact
      661 gctatatttc actaaggata tagcagtgta tctttcatgt cgtttcactg gcagtttttt
      721 ataaaaggag gtgtgcattt cagttgcttt tctttggtag ttagttgaat cgtttaagaa
      781 ttaacggatg tggcagacag gtgctctgtc caaaaaccag taaaatcttt gatggttcca
      841 tctttattta gctgtgcctg ttcaaatact gttttgtttt taccgaatgg atcaattgca
      901 ataattgttc cgatccccgc acgtttggca gcaagtaatc ctgagtaagc atcttcgata
      961 acaagacaat cagccggagc taagctcagt ttgtctgccg ctttaagaaa aatatccggt
     1021 tgcggtttcc cagggaaaga gccgtcgtca tagacaatct tgtcccagtc aaaccagcgg
     1081 gctaaatcga aaatatcaaa ataaaaagca acattctctt tgacagtagc cgtggcaatc
     1141 gttaatggaa tctgttggtc agtcagctgg tcaagagtcg cttcaagccc ttttgtcaac
     1201 tgaagctcgt tttcattttg caagcaaagc atacgataat agctttcttt ttcttctgac
     1261 aatacggcga tctcagaggc ggtcaaatgc tctgaaatga aatgtttcaa aatctccgta
     1321 ttcgtccgac catgaatatt ttttaaaata tcctcgtctg ataaaccatc ttttgtatga
     1381 tcatgtatca tatgcagcca agcagcttca tgcagatgag agtccaaaaa cattgttccg
     1441 ttgaaatcaa atataatccc tttcatagtt acgctcctat agtggtattt tcggttgaat
     1501 cagcaatttg cagatcgaca tattgtgcat agtgctcttg aacctcccgc gagatctggc
     1561 gatccgtaat gagcagatcg aaatcatgca aattataaaa cacataaaaa tcatctcgat
     1621 tgaatttttt attatcaacg agtagatatt tcttacggga attatttaga gcgatctgct
     1681 gtgcttctcc ttcttcggta ctgtaagtag agatcgcttc gttgtgaacg ccatttgaac
     1741 tgataaatgc ttttgtaaac tttagtcttc ttaaattgtc gttggtgatc ggtccgacaa
     1801 atgcgccggt atttttccgg aaatcaccgc caatcagtag aatttctggt ccatctgctt
     1861 gagcaagaat atcaaaaact ggataattat ttgtaatgat ccgaattttc ttgttcagta
     1921 aatgcgtcgc caatagttcg attgttgtac ctggtcctaa gaaaatcgtt tctccctcgt
     1981 gaatcaagga ggctgctgtg gcagcaattt cttttttttc ttgaatctgc agagtggctt
     2041 tttcagtgtg agaaagttct tgatctaaag tgtaggaaag actttgagcc cctccatgga
     2101 cacgcagcag cttgcccgat ttttctaatt catctaaatc tctgcgaacg gtcatatcag
     2161 aaacatctaa ttgattgatg atttcattaa cggtaaggat tcctttttta ttgaccattt
     2221 ctacgatagt aagcaatctt tcttttttca acattgtctt cacctctaat ttaaggataa
     2281 tctatcatat aaacggacaa cagtcaatct aattcgaaca aaagtaaaca tttagggtgg
     2341 tttttatgtt tgttacaata gattttattg ctgttttctg gtttttatga ttatttgtgt
     2401 ttgtttttgt tgacaaatgt tttggatgcg tttacaatgc aatcagttag aaagagcgaa
     2461 aactgattat agatttgagg agagatgtac atgcttaaat taccagaaga ttttattttt
     2521 ggcggagcca cagcagccta tcaggttgaa ggagccacta aggaaggtgg caaaggcgct
     2581 gttgcttggg atgacttttt agaggaacaa gggcgattca gtcccgatcc ggcaagtgat
     2641 ttttatcatc aatatgcaaa ggacattgaa ttgtgtgaac gttttggtgt aaatggtcta
     2701 agattatcca ttgcttggag ccgcattttt cctgatggag ctgggaaacc aaatccagaa
     2761 ggaatcgctt tttatcatcg tgtgttcgaa gaatgtaaga aaagaaacgt aacgccgttt
     2821 gtgacgttgc atcattttga tacccctaaa cgtttgtttg accatggaga ttttttgaat
     2881 cgagaaacaa tagaagcatt tgtttcctat gccatttttt gttttcatga attcaaagaa
     2941 gtcaaggtgt ggagtacctt taatgaaatc tatccagttg caaccaatca atatttgtta
     3001 ggtgttttcc caccaggaat caaatatgat tttacaaaga tcgtcgcctg tcttcataat
     3061 atgatggttg ctcatgcccg tgtagtgaac tatttcaaag aaaacgaact tccgggtgaa
     3121 attggtgtag ttcactcatt agagacgaaa tatgcggcaa cagacgcgcc ggaagataag
     3181 catgctgcct ttttagacga tgcattgtcg atccgtttct tattagatgc tacctattta
     3241 ggctattatt caactgaaac cttgactgct cttgatgaga tatgtgaagc aaatcaggcc
     3301 agctatcatt ttcctgaaga agatttcgtt gaattgaaaa aagcatccac gcgtaatgac
     3361 tacttaggga tcaatcacta ccaatgccat tttgtcaaag cttacgatgg agaaaatgca
     3421 atccatcata acggtacggg tgaaaaaggg acctctgttt ataaagtgaa gggaatcgga
     3481 gaacgtattt ataaagaagg aattcctcga actgattggg actggctgat ttatccagaa
     3541 ggtctatatg acttgttgct gcgaattaaa agcgattacc cacattacaa caaaatctat
     3601 atcactgaga acgggatggg gtataaagat cagtttgaag atggcattat tatggatcag
     3661 ccgagaatcg actatttgag agtctatttg gaatccttaa gcaaggcgat aacagccggg
     3721 gtaaatgtga aggggtattt tttgtggtcg cttatggatc ttttctcatg gacaaatggg
     3781 tataacaaaa ggtatggctt gttttatgtt gattttgaaa cccagaagcg ttacccaaaa
     3841 gaatcagctt actggtacaa gttggtcagt gaaaccaaaa cgattattta ataagtgata
     3901 atggaggaag aaaagatgaa taaagaggaa ttacaaatgc ttggttttga gatcgttgca
     3961 tattcaggcg acgctcgcag tacattattg aaattattga aagaagtaag acaaggaaac
     4021 tttgaacatg ttgattcggc gttgaaagaa gccgacgaaa atttaaccct tgcacataat
     4081 tcgcaaacaa aaattttagc ggaagaagca tctgggaaag agatggagat gggattcatt
     4141 tttatccatg ggcaggatca tttaatgacc actttattgc tgagagatct gattcaagac
     4201 tttattgtac tgtacagaca gaatcaagga taggagaaga acgctatgga tggaatcatt
     4261 aaacaaatcg aaaaagggaa agcatttttt gaaaaaatct cacgtaatag ttatttagga
     4321 gccgttcgtg acggattttt aacagcgatg ccagctattt tattttcaag cattttcatt
     4381 ttgattgctg cggttcctga gatttttggt taccaatggc ctgaatctgt ctccacatgg
     4441 ctatggaaag tctataatta ttcgatgggt gttgtagggt tactcgtttc agcaaccact
     4501 gctcgctgct tggctgattc gatgaatcgt cgcttaccga aaaacaaagt aatcaacacc
     4561 acctctgtga tgctggcctc tgtggtaagt ttcctgttgt taagcgtctc tccgattgaa
     4621 ggtggatttt caacggaata tatggggaca aagggactac tggcttcctt tgtcgctgca
     4681 tttttaacag ttaatttata taagttttgt gtgctgaaag atattaccat taaaatgcct
     4741 aaagaagttc ctggaacgat ttcgcaaacc ttccgagata tttttccttt ctctttttca
     4801 gtatttgcgg ccgttttaat tgatttaggc attcgacaaa tcttccaaat ctcatttgca
     4861 gaagcaatca ttacggtgct gcagccgcta tttacagcag ctgacgggta cttaggaatc
     4921 gctattatct ggggagcgat ggcgctgttt tggtttgtcg gtgttcatgg accgtcgatc
     4981 gtggagccgg caattgcggc aattatctat gccaatgtgg aaaccaatct gcaattgttc
     5041 aattccggtg aacaagcttc taaagtactg acggtgggtt tagggaattt tgtaggaact
     5101 atgggaggaa ctggggcaac attggttgtt ccttttatct tcctactctt tgctaagtct
     5161 aagcagttga aggcagttgg gaaagcttcc tttattccag taagtttcgc tgtcaacgaa
     5221 ccattgctat ttgcggcacc catgattttg aacccttatt tttttattcc atttttgtta
     5281 acacctgttg taaacgtttg cctgttcaag ttttttgtcg atgtattggg catgaacagc
     5341 tttatgtacg ttttgccttg ggcaactcca gcaccgatcg gtttggttct aggaacgggc
     5401 atgggtatct tagcttttgt tctagcagcg gttctaatcg tcgttgactt cctgatctat
     5461 ctaccatttt gcaaagcata cgatgctgtc ttagtagaga aagaagcaca aaaagcagag
     5521 gtgatcgcaa ccgaggaagg tgcttctgcc gatgtacgtg aggaagtacc tgtggcagcg
     5581 agtcaagtta tcagcgatgc aaataaagaa atcaatgtgt tggtactttg tgctggcgca
     5641 gggacaagtg cgatgttagc taatgcttta aaaaaaggtg catctgaatc gaaagcaccg
     5701 atcagtgcaa tggcgggtgc ttatggttct cattacgaaa tgctgcagga ttttgatatg
     5761 gtggtcttag caccgcaagt caattcttac tatgatgata tcaaagaaga caccgatcgc
     5821 ttaggaatca agctggttgc gacaaaagga gcagaatata tcggattaac gagagatcct
     5881 gaaaaagctg ttcagtttat tctgaaccaa tttcaataaa ggaggagcca taatgaaaat
     5941 gggaatttgg ttgcgtaaag ctgttttatt tgcagctgtg ttaggggctt tgggggctgt
     6001 ttcaaaaact gttgaagcat ctgccagcga atttattcgc ggagcagata tttcgatcct
     6061 gtcagatatg gaaaaatctg gtgcaaaata ttatgaagac gatatttcaa aagatgcctt
     6121 agagatttta aaaaataatg gtgtcaacta tgttcgactg cgtttgtggc aggatcctta
     6181 taatagtaat ggagaaagtt atggagcagg gacaaatgat ctggaaacga cgattgacct
     6241 tgcaaaacga gcaaaaaatc tgggacttaa ggtgctgctg gattttcact acagtgattt
     6301 ttgggttgat cctgggaaac agaatcttcc taaagcatgg caaggtctga cctttgaaga
     6361 aatgaatacg gcattgtacg actatacaaa gaacgttctg tcggaaatga agcagctgga
     6421 cgtttatcct gatatggttc agatcggcaa tgaactgaat agcggaatgc tctggcctta
     6481 tggcaagtct tggggagaag gcgggggaga atttgatcga ttggctgctt ttttgaagtc
     6541 tggtatccaa gctgttcgag acactcaacc taaaacaact ccagtaatgc tccacttagc
     6601 tgatggtggc gatacaggag catttacttg gtggtttgat gaaatcacga gtcgaggtgt
     6661 gtcatttgat ttaattggag tgtcgtatta tccgtattgg cacggttcaa tgaatgaact
     6721 tcaaaccaat atgaatgcga tcagccaacg gtatggtaaa gaagtgatcg tagttgaaac
     6781 agcttatggg catacaacag cgaatgccga tactatgcca aatgcttttg gtgaagccga
     6841 agcagctgcg gggggatatg aaccaacacc gacaggacaa gcagagtatt tgctggatct
     6901 tgccgatcgg attcaggcag taccgaataa tcgcggggcg ggcttcttct attgggaacc
     6961 tctttggtac aacggaaatg tgagttgggc aacacaagca ggtatgaatt atctcagtgt
     7021 tcaatccact atgggaaacg aatgggacaa ccaagcgatg tttgattttg ctggaaacgc
     7081 cttgccaagc ttgcgtgcgt ttaaacaagc aggggcgcaa ataaatctag ttaaaaatgc
     7141 aagtttcgaa agcgatggac caacgaccag tccttccaat tggcaaacct ggtttcaaca
     7201 aggaaccgct aagggtacga tcaaaacgga agcgggcact ttttttgggg actacaaact
     7261 aactttttgg caggatcaag catacgaggc atcagcttat caaaatgtta gtggcataag
     7321 caaaggaact tacacattga gtgcctatgt aatgtctggg ggagagtttg atactaatca
     7381 gttatatatc aaaaattatg gtggagcgga actaaatact gcggttgtta aaacaagtga
     7441 atggacaaaa attacaatca aagacattcc aattacaaca ggtgtttgtg aaattggggt
     7501 ttatagcaag gcttcaggaa atgcttggac gaacgttgat tttgtttcat tggtgaaaca
     7561 atagactgcg gatcgtttcg attcaagatc ggaggttccc ttcagccaca tcgttagcgt
     7621 agaaggcagg aatcgaacct gcacctcgcc tttgccaaaa ataaccagaa acgatttcca
     7681 gtcattttta ccaaaacgag taaagcacca gacttcatct acactttgta ttatgctaaa
     7741 gagagttcaa cgatttcgta agaagcaatg aaaaaattgc aaaaagttgt gcagataaca
     7801 taaagtttgt ttaagaaagg gtaaccttag aattccgtcg tgaatatgat ttgagcactt
     7861 agatggatag aaaaaagttc tcggaaaaca gttcgttttt cgagaacttc tttttatgat
     7921 aagaatgaaa caaattaact tatattatag tctcttttgg tagggaacca tcttattttt
     7981 aatgaaaatc aagcatttta gctattgaag aatgttgatt tatagggatt ccccctccat
     8041 attatgttgg ctctttattc ccactccact gttgctggtg gtttagaagt gatgtcatac
     8101 acgatacggt tgacgtgggc tacttcgttt acgatacgta cagagatttt ttgcaagact
     8161 tcccatggga tacgggcaaa gtcagcggtc attccgtcga ttgaagttac agcacggata
     8221 ccgactgtgt agtcgtaagt acgtccgtca cccataacac cgacagagcg gatccctgga
     8281 agaacagtga aatattgcca gatatcacgg tcaagtccag cagctgcgat ttcttcacgc
     8341 aagatagcat cagattcgcg tacgatttct agcttgtctt cagtgatttc gccaagaaca
     8401 cgaataccaa gaccaggacc agggaatggc tgacgccaaa cgattgaatc aggcatgcct
     8461 aactgagtcc ctaattcacg gacttcgtct ttgaataatg tgtttaatgg ttcgatcaat
     8521 tcaaattgca tatcttctgg cagtccacct acattatggt gagatttgat cgtctgtgct
     8581 gtttctgtac cagattcgat aacgtcagta tacaacgttc cttgtgctag gaaagagacg
     8641 ccttcttcac cagcaagttt tgttgcttcg tcatcaaaaa catatacgaa ttcattccca
     8701 atgattttac gtttttgttc tgggtcagat acacctttca acttgtctaa gaagcgatct
     8761 cttgcattga ctttgatgat gttcaagccg aattttccgc ctagactttc cattacttgt
     8821 tccgcttcgc ctttgcgtag cagaccgtgg tcaacaaaga tagatgtcaa ttggtcaccg
     8881 atcgcttttt gtaaaagaac cccaacgaca ctagaatcaa cgccacctga aagaccaagc
     8941 aagacttttt tgtcaccaac ttgttcacgg attttttcta cttgcatatc gataaagtta
     9001 tccattgtcc agttaccttc acagtgacaa acatcaaagg caaagtggcg cagcaattcg
     9061 attccgtatt cggaatgacg tacttctgca tggaattgga taccataaaa attacgtgtt
     9121 gtgtcttgga tagaagcaat cggacaatct ttgcttgttc cgactgtttc aaagccttca
     9181 ggaactttag ttaccaagtc accatggctc atccatactg tttgttgttt tggtgtttct
     9241 ttaaacaaga cagcttgatc gcttgttact tctaacaagg ctttcccata ttcgcggttt
     9301 ttagcaggct ctacggaacc gccaagtttg tacgtgatca attgcatacc atagcaaatc
     9361 cctaatacag gaatacctaa attgaagatc tcaggatcga tcccaaatgc attctcatca
     9421 tatacactgt ttggtccgcc agaaagaatg attccctttg gattcatcgc ttttacttct
     9481 tctgcagtaa tgcggtggct caataattcg gaaaagactc caagatcacg aatacgtctt
     9541 gtgatcaatt ggttatactg actaccgtag tctaatacga taatcttttc aacgttcgtc
     9601 atatcggcaa cgtttgtcaa atttattacc cctatccctt taaattttat ctcaaaatag
     9661 tcaaactatt ttaaaatgct aatattttcg catgaaaatc gaatcgatga tatgattttc
     9721 agttttatgg agaattatat cggctcttcc tcgtgtaggc aagatatatt cctgtaaatt
     9781 tttcaaattc acatttttcc atacatcttt tgccatttta aaggcttctt cacgatctcc
     9841 gatagcaaaa cgataataat aattctctgg attttggaaa gccgtatcca gtaacgcacc
     9901 aaaacgatcc aaataccatt tttcgatcag cacgggatcg gcatcgacat agacagaaaa
     9961 atcaaaaaag tcgctgacgt agatttgctg attcgcaggt aattgaagcg tattgatccc
    10021 ctcaacgatc aagatatcag gctgctggat caattcgtac ttgtctggaa tgatatcata
    10081 cacatcatgt gagtaaacag gtacttttat ctcttcctga ccagatttta cacggttcaa
    10141 gaaatcgatc agcatctcca tatcataact ttcaggaaat cctttacggt ccatgattcc
    10201 acgctctttt aatatacgat ttggataaag aaatccgtca gtcgtgatca gctgaacgtt
    10261 tcttcgtttg aaggtacgag acaaaatcgt ctgcagcagt ctggctgttg tactttttcc
    10321 aacggctaca cttccggcga tcccgataat aaaaggcggt acttctacgt atttatgaag
    10381 aaataaacct ttactcaaga acaaagattc aaattctttc atataaagat aaatcagatg
    10441 agcaagaggt acatagatat ctcgaacatc ctgcatggaa atgcggtcat tcaaactttt
    10501 gatattatct agttcatctt gtgtcaaagg tgcttgccca ttacgataaa attctcgcca
    10561 ttcttctctt gccacacggt agtagttcat tggatcattc atattagcct cctgcgttct
    10621 cccatcaatg gaactatttt aacacaaaat aaacgcaaac cccaccactt aagagagatt
    10681 gccgatcttt ttgtataatc tttataatag aaagaaacgg agtcttattc ttgacttgcg
    10741 cacggataca taaaaggata gactgttgtc atgaaagaaa tgagaaggat ggaagacatg
    10801 acaaatcatt actattctga acgcccagat acggcgcacg attttgaaca atgggctttt
    10861 gagttaaaag gcagaacctt tcaatttgta acagattctg gtgtattttc acgtgaaaca
    10921 gtggattatg gttcacgtgt cctgattgat gctttcgatt gggaagagtt acctgatgaa
    10981 ggaaagatct tagatgtggg atgcgggtat ggaccgattg ggttagcttt ggcatttgcg
    11041 acacagcggt ttgttgaaat ggtcgacatt aatgaacgag cggtaagtct agcgcaagga
    11101 aacgcaaagc gtaaccaaat cgaacatgtt gatatccatc aatcgaatat ctatgaagca
    11161 gttcatgaag aaacctatgc agctatcgta agcaatccgc cgatccgtgc tggaaaaaaa
    11221 gttgtacatg aaattttgac aggcgcatat cctcggttga agaagggcgg tacactgaca
    11281 attgtgatcc agaagaaaca aggagcgccg agtgcgcaaa agaaaatgga agaaacattt
    11341 ggtaatgcag aaatcgtcac aaaagataaa ggatattata tcatcaaaag tgtgaaagaa
    11401 taactagctg aaaaatagtg gagcgacgaa agagtggaac tgggcgtgca tgtacgggta
    11461 cgtatcagtt ctttttttgt tgagaagttt ttaaaaacaa agaactattt tttcttcaaa
    11521 aagaaatagt aggaacagag tcgttgtttt ttacgataaa ataaataaga tacagaactt
    11581 gtatagaagg ctgccaagtc ggtagataaa ggaggttttt atcaaaaaac atactttcct
    11641 tttttctcta ttcttttctt gggggttttg gtacactgat agggaattta gatagaaggg
    11701 agccaatagg atgaagctga ccatcagaga tatcgcagaa atggcaggcg tatcagtaac
    11761 aactgtctca cagattttga ataacaaagg aagcagattt agtgataaga caagaaaaaa
    11821 agtgttgtcg atcgtgaatg aacatcatta taagcccgat tatttcgctt caaatgtgat
    11881 caatcgacat tcaaagacca tcggaatgat cgtccctgat gtcactgatt tcttcttctc
    11941 caaactgatc gaaggtgtag agagctattt gaatcctttg ggctatgtga tcatgttatg
    12001 caattctcgt catagccaag aaaatgagat caagtattta caagagcttt cccaccgctc
    12061 agtggacgga atcttgctgg ccacaccaaa tattttacct gagaaatatg cattagacag
    12121 cggtttttat caaaaaatgc caatcatttt aatcgatcgc ggattgaatc gtcgggataa
    12181 cggacggctt atcgtaaagg aatatgaggg cgcctatcaa gctgtttcgc tgtttattga
    12241 aaatggccat acgaagatcg gcatgctgaa ggaaaccact ggatactatc aattagaaga
    12301 acgtttcaac ggatatcgtc atgcgctgaa agatcatggc ctgcctttta atgggaaatt
    12361 tgttgaacat ggagagttga ctgtccaagg tggatatact gcatcaaaaa aattactcaa
    12421 acataaagat atcacggcta ttttttgcgg gaatgatgcc atggcgatcg gatgctatca
    12481 ggcgatcgat gaattgggca aaaaaatccc agaagatatc tcagtcatag gattcgatgg
    12541 attaaagctg tcagaataca tgattccgca attgacgaca gtgcagcagc caagttttga
    12601 tattggattt tatgctgcac gtttcctgat cgatacgatc gaatttcctc aaagaaaagt
    12661 tccgaacaaa gtgttcgaaa caaaattaat tattcgtgag agcgtaaaag tattgacaaa
    12721 gggctaactc ggcggtatat tgcttatgta agcatttaca aaggctagtt agtgcttttt
    12781 ttatttttag taaaccagtt tactaaagtg gtttaccttt cctaaaaata atgtataata
    12841 ccgaatgaag acaaggagga tcaggcaatg cgaatggtgg atctgattga aaaaaagagg
    12901 gatggaaacg agctgtcgaa agaggaaatc gagtacatcg tcacgaacta tacgaatgga
    12961 aagattccag attatcaagt cagtgcatta ttgatggcaa ttttttatca agacatgaca
    13021 aatgaagaaa tcacgaactt aacattggcg attgctaatt ctggtgatgt catcgatttg
    13081 agttctcttg aaggaataaa ggtagataag cattcgacag gtggcgttgg tgacacgacc
    13141 acattgattt tagcccccct agtagctagt gtcggagtga cagtggctaa aatgtctgga
    13201 cgcggtctag gttacacagg tggtacacta gacaagctag aagcaattcc cggatttcag
    13261 atcgagcttt cggatgaaga atttgtacgc attgttaatg aaagtaaagt agcggtaatt
    13321 ggtcaatcag gaaacttggc accggcggac aaaaaattgt atgccttgcg tgacgtcaca
    13381 gcgaccgttg attctcttcc gctgattgcc agttcgatta tgagtaaaaa aatcgcggca
    13441 ggagcagatg caatcgtttt ggatgtgacc actggagacg gtgctttcat gaagaacatc
    13501 gaagatgcaa gacgtctggc aaagaccatg acgagcattg ggaaactggc taaccgagaa
    13561 acagtggcgg ttatctcaga tatgtcagaa cctcttggcg aagctatcgg aaatagtcta
    13621 gaagttgtcg aggcaatcga aacattacaa ggaaatggtc cagaagatct agtagaaatg
    13681 tgctacgcct taggaagcca aatggttgtt cttgctggca aagctaagac aaccgatgaa
    13741 gcaagaacgt tgcttcaaga agctctggaa tcaggtaaag cgttagcaaa attcaaagaa
    13801 atgatccaaa atcaaggggg agacccagcg atcgtggaac atccagaacg aattttgact
    13861 gcacgctaca caatggagct tcctgctaaa caaagcggag ttgtgtcaaa aatcgtggca
    13921 aatgaattag gaattgctgc aatgatgcta ggtgctgggc gtaaaaccaa agaagaagat
    13981 attgatcacg ctgttggatt gaaactgcat aaaaaaattg gtgacactgt gacaaaaggt
    14041 gagtcactat tgacgatcta tagtaacgac gaagaaatca cttctgtcat tgaattatta
    14101 tataaaaata ttgaaattgg tgaatcggca atgaagccaa cgttgattca tgacatcatc
    14161 acagaataaa ggaaaaaagc ggactttacc gttttaaaga aaaggggaaa agaaatggaa
    14221 ctaaaccgaa tgatcgacca tactattttg aaagcagacg catctaaaga agctgtgatg
    14281 caaattatcg aagaagcaaa aaaataccat ttttattctg tctgcatcaa tccagcatgg
    14341 gttgcgctag cgaaagaaca attacaaggt gagccagtag ccgtatgtac agtaatcggg
    14401 tttcctctag gagcaaacac acccgagaca aaagcatttg aaacaacaga tgccatcaat
    14461 aacggtgcag atgaagtcga tatggtcatc aatatcggtg ctttgaaatc aaaggatgat
    14521 caacaagtcc aaaaagatat cgaagcagtt gttgaagcag caaaagatcg tgcgcttgtc
    14581 aaagttatta ttgaaacatc gttattagat agagaagaaa tcatccgagc ttgcgaaata
    14641 gcaaaagctg caggcgctga ttttgtcaaa acatcaactg gtttctcaac aggcggagca
    14701 aaggtagagg atgtccgttt gatgcgtgaa actgtaggac cagaaatggg tgtcaaagct
    14761 tccggcggta tccataacga agaagaagca atggcaatga tcgaagctgg tgctacaaga
    14821 atcggaacaa gcgcaggagt agcaatcgta tctggttcaa ctggtgaagg ctattaattt
    14881 tttcaaagga gaagctcatg gcagaactca aacaagaatg gatcaacaca gctattgaag
    14941 cgttagataa agcctatgtt ccttattccc attttccggt aggcgcttgt ctcgtaacgg
    15001 aatcaggcaa gatttatcaa ggcatcaaca ttgagaatgc atcatttgga ttaacgaatt
    15061 gtgccgagcg cacagctttt ttcaaagcag tatctgaagg agaaaaaaca tttacgcatc
    15121 tagtcgtagc ggggcacacc cccgatccta tctctccttg tggtgcatgt cgacaagtaa
    15181 tggcagaatt ctgttcccct gatatgccgg ttacgctagt aggagacaat ggtgtgacga
    15241 aggcaacgac cgttcgtgca ctgctgcctt atgcatttac tgaaaaagat ctataactca
    15301 tgttcattca gtcagctgac tgttgaaaaa taaaacaatt attttaggag gctttacaga
    15361 aatgaaaaaa gcaaaattat ttggtttagg tgctgtcgca ctagcagcag ggttattttt
    15421 aggtgcatgc ggcaacaacg gctctactga ttcatccggt ggcaaaagct catcagacac
    15481 aacaactgca gcattgatca cagacacagg tggtgtagac gaccgttcat tcaaccagtc
    15541 agcttgggaa ggactagaaa aatgggggaa agatcaagga ctttcacgag gaaatgatgg
    15601 cttccaatat ttccaatctt caaatgaatc agattacatc ccaaatattg accaagcatt
    15661 gaatgctgga ttcaaaacga tttttggtat tggttataaa ctaaaaccag cgatccaaga
    15721 acaagcaaca aacaatacag gtacgaactt tgttattatc gatgatgtca tcgatggatt
    15781 agataacgtt gtatctgcaa ctttcaaaga caacgaagct tcttatcttg caggtgttgc
    15841 agcagcttat acgactgaaa caaacgtagt cggctttatc ggcggtgtaa aaggtgaagt
    15901 aatcgatcgt tttgatgctg gattcaaagc cggtgttgat gcaggtgcga aagaattagg
    15961 aaaagaaatc aaagtattga atcaatatgc tggtgacttc tctgctccag ataaaggacg
    16021 ttcaattgct caaggtatgt atgcacaaaa cgcagatatc atcttccatg cttcaggcgg
    16081 tacaggtaac ggtgtattcc aagaagcaaa atcattgaac gaatcaggcg acaaaaaagt
    16141 ttgggttatc ggtgttgacc gcgaccaatc agacgaaggc gaatacacat taaacggcga
    16201 aaagaaaaac ttcacattga catctacact gaaagcagtt ggaacagtag tagaagattt
    16261 ggcacaaaaa tcagcggacg gtaaattccc tggcggcgaa cacactgttt atggattgaa
    16321 agaagacggt gttggtctaa cagaaggaca actttctgac gaagcgaaaa aagcagttga
    16381 tgaagcaaaa gaaaaaatca tttcaggtga cgtaaaagtt ccagaaactc ctgaagaaaa
    16441 ctaaaaccat ttctatagcc ttgttagaca catgtttgac aaggctatgg tttgattaga
    16501 acaagaattg ttcatttatc caagctgcct tgtgacagtt tggataaggg aacaactccc
    16561 tgaagtaatg tttgtttcaa aagaagaacg ctcactaagc gtgaatctta gtcaatcgtt
    16621 gccctagata gaaatcgtta ggatgtgaaa aaaaggtggt tcaagaaaat attgtcatag
    16681 aaatgcagaa tattaccaaa gaatttggaa cattcaaggc aaatgacaac atcaatttac
    16741 aagtaaaggc aggagaaatt catgcgttgc ttggagaaaa cggtgctggc aaatctacat
    16801 tgatgaacgt gctttccgga ttattagagc cgacatcagg gaaaattttg atgcgtggga
    16861 aagaagtaaa gatcacaagt ccgaccaaag ccaaccaatt agggattggg atggtccatc
    16921 agcactttat gcttgttgat gcctttactg taacagaaaa catcgtgttg ggaagcgagc
    16981 ctagtcgcgc agggatgctt gaccataaaa aagcacgaaa agagatccaa aaagtttctg
    17041 aacagtatgg attgtcagtc aacccagatg cttacgttcg tgatatttca gttggaatgg
    17101 aacaacgggt agaaatttta aaaacacttt accgaggagc agatgtactg atttttgatg
    17161 agccgacagc tgtattgacc cctcaagaaa ttgatgaatt aatcgtgatc atgaaggaat
    17221 tagtcaaaga aggcaagtcg atcattttga ttacgcataa gttagatgaa atcaaagcag
    17281 tagctgaccg ctgtacagtt atccgccgtg gaaaaggaat cggtacagtc aacgttaaag
    17341 acgtaacctc acaacaatta gccgatatga tggttggaag aacggtttca ttcaaaacga
    17401 tgaaaaaaga agcgaagcct caagaagtcg ttttgtctat tgaaaatcta gtggtgaaag
    17461 aaaatcgtgg attagaagcc gtgaaaaact tgaacttaga ggttcgtgct ggcgaagtac
    17521 ttggtatcgc tggaatcgat ggaaacgggc agtcggagtt gatccaagct ttgactggtt
    17581 tgcgaaaggc agaaagcgga catatcaagc taaaagggga agacatcact aataaaaaac
    17641 cccgaaaaat cactgaacat ggtgtaggac acgtgccaga agaccgtcat aaatacgggt
    17701 tagtcctaga tatgacatta tctgaaaata tcgcactaca aacctatcat caaaaacctt
    17761 acagtaaaaa cggcatgctg aattattcag taatgaatga acatgccaga gaattgatcg
    17821 aagaatatga tgttcgaaca acgaatgaac ttgttcccgc aaaagcttta tcaggcggaa
    17881 atcagcaaaa agcaattatc gctcgtgaag tcgaccgaga tcctgatctg ttgattgttg
    17941 caaatccaac tcgtggactg gatgtaggtg cgatcgaatt tattcataaa cgtctgatcg
    18001 aacaaaggga caaatacaaa gcagtgttac tgatcagttt cgaattagaa gaaattttaa
    18061 atgtttcgga tcgtattgct gttatccatg aaggagaaat tgtcggtatc gttgatccga
    18121 aagaaacatc tgaaaatgaa ttaggtctat tgatggcggg ctatacctta gaagaagcac
    18181 gaaaagagtt agaaaagggg gctggcgcac atgaatgatc gcagcgaaaa attccgtaat
    18241 ttattagtgc ctgtactttc agttgtttta ggattgatct taggcgcgat attgatggct
    18301 gcttttggtt ttcagcccat ccaaggttat tcttctatgc tagatgcagc ccttggttcg
    18361 caaagaggga taggtgaaac gttaaggcaa gcaacgccgt tgatttttac agcattaggt
    18421 ttttctgtag ctaactcagc tgggtttttc aatattgggc tttctggaca agcactttgc
    18481 gggtggatcg tcagtgtctg ggtggcactt gcgtttccag atctgccaaa agttgttttg
    18541 cttccgttat gcgtgatctt aggtgcctta gctggtgcga tggcagcggc tgttccaggt
    18601 ttacttcgag cattttttgg aacaagtgaa gtgatcgtaa caatcatgat gaactatatc
    18661 ttattatacg taagcacatt tgctttacat gaagtgatgc ctgaaagcta tcgctcaagt
    18721 ttggactctt ccaatatgat cagtcaaaat gcctcactgc ggttaccatg gttaacacaa
    18781 gcttttggcg gctctcgcgt aaactcagga ttatttttag caatcatcgc gcttattttc
    18841 gtttggctgc tgatgaagaa aacgacttta ggatttgaaa tccgttctgt tggattgaat
    18901 ccttttgctt ctgagtatgc aggaatgagt agtaaacgta cgatcgtttt gtcgatggtc
    18961 atttctggcg ctttggcagg gcttggcggt gtggttgaag gattaggaac gtatcaaaac
    19021 ttctttgttc aaacgacttc gctatctatt ggatttgacg gaatggctgt ttccttgctt
    19081 ggttctggat cagcaatcgg tattctttta tcagcgatct tgttcagtat tttgaagatc
    19141 ggtggacttg gcatgcagac aggagcaggt gttccgtttg agatcgtcaa tgtatcgatt
    19201 gctttgatta tcttctttgt cgggatcaac ttcctgattc gtttcgtcat ggctaaagtc
    19261 ttccaaggga aaaaacaaga agagatcgtt gcgacaatag aatcgaaacc aacgaatcaa
    19321 aaccatgaag ggggcgaact ataatgtcga ctatcgaatt aattgccttg atccttactt
    19381 ctacactggt ttattcaaca ccgctaattc taacgtcact aggcggaact ttttctgaac
    19441 gaagcgggat cgtaaacgta gggctagagg gaatcatggt catgggtgct tttagttcca
    19501 tcgttttcaa cttgacgatg agtccatcac ttggttctat gacaccatgg atcgctattt
    19561 tagtgggtgg cgtcgtaggt atcctatttt ctctgattca cgcagtagca acagtcagtt
    19621 tgcgtgctga ccatattatc agcgggacag taattaatct gatggcacct gctttaggtg
    19681 ttttcttgat caaagcatgg tatggtaaag gtcaaactga taacatcacg cagaatctgg
    19741 ggtatttttc tttcccagga ttagcagata ttccggtcat tggaccaatt ttctttaaaa
    19801 atacattctt acctgcttat tgtgctattt tgattgctgt cctagcttgg gtgatcatct
    19861 tcaagacgaa attcggcttg cgcctccgtt cagttggtga aaatcctcaa gctgccgaca
    19921 cattaggtat caatgtatat gctatgcgtt attcaggcgt actgatttct ggcttgttag
    19981 gcggtatggg cggtgctgtt tttgctcagt cgatttccgg taacttttca gctggtacga
    20041 tcgttggaca agggttcatc tccatggctg ctatgatctt tggtaagtgg aatcctttag
    20101 gggcaatggg tgcctcattg ttctttggtt ttgctcaaag cttgagtatc attggcgcac
    20161 aattaccagt tatttcttcg attccgccag tattgctgca aattgctcca tatttgctga
    20221 caatcattgt gctggttgtt ttcttaggga aagcttctgg tccaaaagca aacgggaaga
    20281 actatatcaa atcaaaataa tcttttagcg aataaaaagg gtgggttacg ggaagtgttt
    20341 ttcgtctcgc cctttttgtt ttaaaggcaa taaaaataaa aagaaagaag gaataatcat
    20401 gtttaaacgc gtacatctga tcgtcatgga ttcagtagga attggagaag caccagatgc
    20461 cgataagttc ggtgatgttg gttctgatac attaggacac attgcgaaag aagcaggatt
    20521 gaacgttcca catttagagc agcttggttt aggaacgatc cgtcctcttg aaggtgtgga
    20581 atcagtgaaa gatcatcaag gctatgcgac gaaattagaa gaagtttctg tagggaaaga
    20641 tacgatgaca ggccactggg aaatcatggg attgaatatc aaaactccat ttcgtgtgtt
    20701 tcctaatgga ttccctgatg atctgatcaa acaaatcgaa gaattttctg gccgtaaagt
    20761 cgtatgtaac aaaccttata gcggaacagc tgttattgac gattacggtg aacaccaaat
    20821 gaaaacaggc gatttaattg tatatacttc tgccgatcct gtccttcaga tcgcggcaca
    20881 tgaagaaatc attcctttag aagaattata tcggatttgc caattcgttc gtgatataac
    20941 aaaagatgat ccgtatatga ttggccgaat cattgcacgt ccgtacgtgg gtgaaccagg
    21001 agacttcaca cgaacaagca atcgccatga ttatgcgttg aatccattcg gacacacagt
    21061 ccttgattct ttgaaagaag caggaaagga cgtgattgct gttggaaaga tcaacgatat
    21121 tttcaacgga caaggaatca ctgaatctgt ccgcacgaaa agcaatatgg atggcgttga
    21181 ccagctgctg aaagttatga aaaacgattt ttcaggaatc agctttacca atttagtaga
    21241 ttttgatgca ttatacggtc atcgtcggga tgtagtcggc tatgcgcatg cgattgaaga
    21301 atttgactta cgaattccag aattgcttga agcgatggaa gaagacgact tgctaatgat
    21361 tacagccgat cacggaaacg atccgacgtt tactggtacc gatcatacgc gagaatatgt
    21421 accgttattg gtttacagta aaaaaatgaa agaacaaggg gcattgcctc aaggatatta
    21481 ttcagatatt tcagcaacga ttgctgagaa ctttagtgtt tcttcgactg aaaatggcga
    21541 aagcttcttg aaattattaa aataatcttt ttaaatagga gaaagcaaat gaccaagtta
    21601 agcgagatgt tacaagaaac gacccagttt atccttgata aaggagtaaa agaaattgat
    21661 tttggtttga ttctaggttc aggattaggt gaattagcag atgaaatcga agatgctgta
    21721 atgatttctt atgatgagat cccgttcttt cctgtttcga cagtagttgg gcatgcagga
    21781 aagctagttt atgggtctct ggcaggcaag aaagtgttag ccatgcaagg gagattccac
    21841 tactatgaag gtcattccat gcaaacagtg acctatccag tacgtgtgat ggccggacta
    21901 ggggcccatt cagtcattgt gactaatgca tgtggtggtg tcaacgaatc atttgtacca
    21961 ggagatttga tgctgattac cgatcatatc aattttactg gtgaaaatcc tttgatcggt
    22021 ccgaatgaag atgcaatggg ccctagattt ccagatatga gtcaagctta tacgcctgac
    22081 tatcaagcaa cagcaaaagc agcagcagaa aaactaggtt tggatcttaa agaaggcgta
    22141 tatatgggct attctggacc aacttatgaa acgcctgcgg agatccgaat gtctcggaca
    22201 ataggagccg atgcagtagg gatgtcgact gttccagaag tcatcgtagc agctcacagc
    22261 ggattaaaag tgttaggaat ctcttgtatt accaacttag cagcaggtat gcaagcgaat
    22321 ctgagccatg aagaagttgt agaaacaact cagagagtca aacaatcttt taaagcattg
    22381 gttaaagaaa cattgacatt attgtaatag gaggaacaat aaaatgagtg tgcatattga
    22441 agcgaaagaa ggcgagatcg ccgataagat tttacttccg ggagatcctt tgcgagctaa
    22501 atatattgcg gagacttttt tggaagatcc agtttgttac aatcaggtac gcggtatgtt
    22561 aggctttacc ggcaaatata aaggagaacg tatttctgtt caaggaacag gaatgggaat
    22621 gccatcagcc accatctatg cccatgaatt gatccagtcg tatggtgtaa agaaattgat
    22681 tcgagtaggt acatgcggtg cattgtcaaa agacgtccat gttcgtgatt tagtactagc
    22741 acaaggtgca gcgaccagtt cttcgatgat cgaaaaaaat ttccaagcct ttcattttcc
    22801 tccaatcagt gatttcaatc tattactgaa agcatatgag atagctaaag aaaagggcta
    22861 tacggttcat gtaggaaatg ttctttcgga agattctttc tacaaagatg atttgacaga
    22921 gacgttccaa ttagctgaac ttggcgtttt aggagtggaa atggaagcag cggctcttta
    22981 ttacttaggc gcgaaatacc atgtgcagac attaagtttg atgaccgtta gcgaccattt
    23041 gatcaccggt gaagaaacaa cagctgcaga acgtcaatct acgttcaatg aaatgatcga
    23101 agtaggattg gaaacagcga tagcagaata agaaggaaat gaaaaagctg ccctgcatta
    23161 agtaataaga acatccaagc aaaaatagct cctcatgttt ttgacttggc tggacttatt
    23221 attgcaaatg taagcttttg aacaccgttt accaagaggt tgtgaatctg ccgtttaact
    23281 ctgagtcaca aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt
    23341 gtgaccgaga agttggcagg agaaaaccgt ttatacgaaa aaagggactg tgacaaatcg
    23401 tgtcacagtc ccttttttat agtgtttttt ataggtagta ttttttagca actgttaagt
    23461 catcatttaa ttcataaaca agtggttgac ctgttggaat ttcaagatcc atgatgtctt
    23521 cgtcagagat accttcgata tgtttagcta gggcgcgtaa tgagttacca tgtgcagcta
    23581 ctaaaacagt tttgttgtct agtaatgctg gagcaatttc atcttgccag aatggcaaag
    23641 cgcgttctaa tgtcactttc aagttttctc caccaggaat atcgcgtttg tctaacattg
    23701 cgtaacgacg gtcatttgct gcagaacctt cgtcagtttc ttccattaat ggaggaagag
    23761 tatcgtaaga acgacgccag atgtgcactt gttcgtcgcc gtatttttca gctgtttctt
    23821 ttttgttcaa accttgtaat ttaccatagt gacgttcgtt taagcgccat gatttgattt
    23881 gtggtaccca aagttgatct gaatattcta agatcaagtt acatgttttg attgcacgag
    23941 ttaaaacaga agtgtaagca acatcaaatt cgattccagc ttctttgatt ttgcgtccgc
    24001 cttcttttgc ttcttcgatt ccttctggtg ctagatttac atcagcccaa ccagtaaatt
    24061 ggttcaatgc attccattca ctaagaccgt gacgagaaaa aactaatttt ggcatgttta
    24121 gctctccttt taagataggt ttatatttct gaaattttca gttctgtttt attgtacaat
    24181 tttttggaag agatttccat cgaaaaatta gataagattc tatgagaaaa caagtagaga
    24241 atataaaaaa acgaacagtg cccacgcaac tgttcgtttt taggtattag atgcataatt
    24301 gctcgatttc tttttcaggt aaattgatat atttataaca tgttccaact gaaacaccgc
    24361 attttgaaga aataaattgg atcgtttctt ttttttcata atagagacgt cggatttttt
    24421 tgatcgtttt tgcatcgatt tttggtcttc cgccgatttt tcctttttta cgagcttcat
    24481 ctaatccaac taatgtacgt tctttgatca atgcgcactc catgtttgct aggttttcca
    24541 ttaattggaa atagattttt cccatttcgc gcgtatcgat tccttcatca agactaatca
    24601 agtgcagccc gcgatctttg aataattgcg tgagttctgt taattgccgc gtagatttgc
    24661 ctaatcgatg aagttggcaa atgactagtg catcgccttg ttgcatgtca gcgatcactg
    24721 actccaaatg aacagcagta gaatcatttt gttccacttc atatgtctca tggaaaattt
    24781 cttgacaacc aaagtcagat aattgatcaa cctgagttgt taaatcaacg tcatttatgg
    24841 ttgtgcgtgc ataaccaata attttcatgg tgattccttt ctagcagtga ttttctaact
    24901 ggatataaca gtaaaaatgt agcataaagt acgtcaaaaa gatagttttt tcgcaaattt
    24961 tccgctgtct ttttttattg gatgatcaag cagtttttct ttatttacga cggattgcgt
    25021 caagaatctc aacgcctttt tctgagccga caactacttt agaaaccatg tttaggaaaa
    25081 gcccatgttc tactacccca acaagttcat ctaaataggt agctaagctt tctggctgtt
    25141 cgatgacttc tagatgcaga tcaatgatgt aatgaccacc atctgtggtt aagacttctc
    25201 cgttttcgtc tgtacgcaag acgggttgga atcttttttc ttcaaaaata tgaagtagct
    25261 gttgggagcc ataagggatc acttcaactg ggagtgggaa cttcccaagt ttatcgacta
    25321 atttagaaga atcaacgatc caaatcgttt cttttgagta cgtagcgact attttctcga
    25381 aaagcaaagc agcgccgccg cctttgatcc cttgaaaatc agcactgatt tcatcagcac
    25441 cgtctattgt caaatcgact acggggactt catcaatact ctttaacggt attcctaatt
    25501 tttccgcttg ttcttttgtc gcatttgaag tagtaactcc tgtgatacgt aaaccttctt
    25561 cacgcatacg gcgaccaatc tcttctacca tataataggc ggttgaaccg gtcccgagac
    25621 ctacgatcat cccgtccttt acgaatttcg cggcttcaat gccagctaat tgttttaaat
    25681 tcatctttgc gtccaccttt ttttagtttg agcatcgtgc tttcctcact attttagcgt
    25741 gatttacggt aaaaagatac cattcttttt tattccaata aagctttttc aaaaaaaatt
    25801 gcatctcttg ttgacatgtt ttttcattcg tgatattcta acaaaggtgc tttatctaca
    25861 ggtttctgtg aagaaacgtg ctgactgttt atcaaagcat atttgataag gatgcagaca
    25921 ttgcatttat tttttatcac aaaaaaagaa ccacctggat gtgtggaact agacgcaaat
    25981 cgtgggaagg aggaaacaag gaatgcctac aattaaccaa ttagtacgta aacctcgtaa
    26041 atcaaaggtg gaaaaatcta attcacctgc tttgaacaaa ggatataaca gctttaagaa
    26101 aactcaaact aacgtaaact cacctcaaaa acgtggggta gcaactcgtg tgggtacaat
    26161 gacacctaaa aaaccgaact cagctttacg taaatatgca cgtgttcgtt tgtcaaactt
    26221 aattgaagtt actgcttata tcccagggat tggtcataac ttacaagaac acagtgttgt
    26281 attattacgc ggtggtcgtg taaaagactt accaggggta cgttaccata tcgttcgcgg
    26341 tgctttagat actgctggtg ttaacgaccg taaacaaagc cgttctaaat acggaactaa
    26401 aaaacctaaa gcttaatttt aattattaaa caaatgaaac ttgcttctac tatatagaag
    26461 taattactat gaacaatatt tcggaaggag gagttacgga tgccacgtaa aggtcctgtt
    26521 gcaaaacgtg atgttttacc agatcctatt tataactcaa aattagtaac tcgcttgatc
    26581 aaccgtgtaa tggttgacgg aaaacgcggg attgcagcta acattatcta taatgccttt
    26641 gacttgatca aagaatctac aggtaacgat ccattagaag tgtttgaaca agcaatgaaa
    26701 aacgttcaac ctgttcttga agttaaagca cgtcgtgttg ggggttcaaa ctaccaagta
    26761 ccagttgaag ttcgccctga acgccgcgtt actctaggtc ttcgttgggt agtaaactac
    26821 gctcgcttgc gcggtgaaca cacaatggaa gaacgcttag caaaagaaat catggatgct
    26881 gcaaacaaca caggtgcttc tgttaaaaaa cgtgaagaca ctcataaaat ggctgatgcc
    26941 aaccgtgcgt ttgctcacta tcgctggtaa gattctctct gtttggtcgg cttttataag
    27001 tcgacctcag atagtgtcct tatttttagc aactagatag taaagagagg agaaacaagg
    27061 agaatgacca gagaattttc tttacaaaac actcgtaata tcggtatcat ggcccacatc
    27121 gatgctggta aaacgactgc tactgaacgt atcttgtact atactggtaa aatccataaa
    27181 attggtgaaa ctcatgaagg agcttcacaa atggactgga tggaacaaga acaagaacgt
    27241 ggtattacga tcacttctgc tgctactaca gcacaatgga agggtcaccg aatcaacatc
    27301 atcgacacac caggacacgt agacttcaca gttgaagttg aacgttcatt gcgtgtactt
    27361 gatggtgctg taactgttct tgatgcacaa tcaggtgttg aacctcaaac tgaaacagtt
    27421 tggcgtcaag caacaactta tggtgtacct cgtatcgtat ttgcaaacaa aatggacaag
    27481 atcggtgctg acttcttata ttcagtatca actttacatg accgtttgca agcaaacgct
    27541 cacccaatcc aattaccaat tggtgcggaa gacgacttca caggaattat cgaccttgta
    27601 acaatgaagg ctgaaatgta tacaaacgat cttggaacag agatcgaaga aacagaaatt
    27661 cctgaagaat accgcgaatt agctgaagaa tggcgcgaaa aattggttga agctgtagct
    27721 gaaactgatg aagaacttac tttgaaatac ttagaaggtg aagaaatcac tgaagctgag
    27781 ttaaaagaag gtatccgccg cgcaacagtt aacgtagaat tctacccagt actatgtggt
    27841 tcagcattta agaacaaagg ggttcaatta ctattggacg ctgttcttga ttacttgcca
    27901 tcaccgttag atatcccagc tatcaaaggg attgacccta aaactgatga agaagtagaa
    27961 cgtcctgcag acgacagcgc tcctttctca gctttagcat ttaaagttat gactgaccca
    28021 ttcgtaggtc gtttaacttt cttccgtgtg tactctggtg ttttacaatc aggttcatac
    28081 gtacaaaacg caacaaaagg caaacgtgaa cgtgttggtc gtatcctaca gatgcatgcc
    28141 aactctcgtt cagaaatctc tgaagtttac gctggagata tcgctgctgc tgttggtttg
    28201 aaagacacaa ctactgggga cacactatgt gatgaaaaga gtctagttat tcttgaatcc
    28261 atggaattcc cagaaccagt tatccaagtc gctattgaac ctaaatcaaa agctgaccaa
    28321 gataaaatgg gtgtggcttt acaaaaacta tctgaagaag atcctacttt ccgtgctgaa
    28381 acaaacgtgg aaacaggcga aacaatcatc gctggtatgg gtgaacttca cttagatatc
    28441 atcgttgacc gtatgcgtcg tgaattcaaa gttgaagcta acgtaggtgc gcctcaagta
    28501 tcttaccgtg aaactttccg tgctggcact caagccgaag gtaagtttgt acgtcagtct
    28561 ggtggtaaag gtcaatacgg tcacgtatgg attgaattta caccaaatga agaaggtgct
    28621 ggtttcgaat ttgaaaatgc gatcgtcggt ggggttgttc ctcgtgaata cattccagct
    28681 gttgaaactg gtttgaaaga tgctatggaa aatggtgtct tagctggcta tccattagta
    28741 gatatcaaag ctaaacttta cgatggttca taccatgatg tcgattcaaa tgaaactgcc
    28801 ttccgtgttg ctgcttctat ggcattacgt gcagcagcta agaaagctaa tccagtaatc
    28861 cttgaaccaa tcatggctgt agaagttgtt atccctgaag attatttagg tgatgttatg
    28921 ggtcacgtaa ctgctcgtcg tggacgtgtt gaaggtatgg aagctcgcgc tggcggccaa
    28981 caagttgttc gtgcgatggt tccacttgct gaaatgtttg gttatgctac aactcttcgt
    29041 tctgctactc aaggtcgtgg tacatttaca atgacatttg accactacga agatgtacca
    29101 aaatcagtac aagaagaaat cattaagaaa aacggcggaa aagctgaata atttcttgaa
    29161 accggatagt cctgcaaaga gattatccaa agagactata tttttaatat agtttcgtgt
    29221 aaaataatta tcgatgatat gggcatgtgg tgtaccttgt gtacatcata tacctatcag
    29281 acaaataaaa aatatattgt atttttagga ggacatttta aaatggcaaa agaaaaattt
    29341 gaccgttcta aaccacacgt taacattggt actatcggac acgttgacca tggtaaaact
    29401 acattaacag ctgcaatcac aactgtacta tctaagaaaa acggcggcca agctatggct
    29461 tacgatcaaa tcgatggtgc tccagaagaa cgcgaacgcg gaatcacaat ctcaacagct
    29521 cacgttgagt atgaaacaga tacacgccac tacgctcacg ttgactgccc aggacacgcg
    29581 gattacgtta aaaacatgat cactggtgct gctcaaatgg acggagctat cttggtagtt
    29641 tctgctgctg acggcccaat gcctcaaact cgtgaacaca tcctattgtc tcgtcaagtt
    29701 ggtgttcctt acatcgttgt attcttgaac aaagtagaca tggttgatga cgaagaatta
    29761 ctagaattag ttgaaatgga agttcgtgac ctattaacag aatacgaatt ccctggtgac
    29821 gatgttcctg tagttgctgg atcagctttg aaagctctag aaggcgacgc ttcatacgaa
    29881 gaaaaaattc ttgaattaat ggctgcagtt gacgaataca tcccaactcc agaacgtgac
    29941 aacgacaaac cattcatgat gccagttgaa gacgtgttct caattactgg acgtggtact
    30001 gttgctacag gtcgtgttga acgtggacaa gttcgcgttg gtgacgaagt tgaagttgtt
    30061 ggtattgctg aagaaacttc aaaaacaaca gttactggtg ttgaaatgtt ccgtaaattg
    30121 ttagactacg ctgaagctgg agacaacatt ggtgctttac tacgtggtgt tgcacgtgaa
    30181 gacatccaac gtggacaagt tttagctaaa ccaggtacaa tcacacctca tacaaaattc
    30241 tctgcagaag tatacgtgtt gacaaaagaa gaaggtggac gtcatactcc attcttcact
    30301 aactaccgtc cacaattcta cttccgtaca actgacgtaa caggtgttgt tgaattacca
    30361 gaaggaactg aaatggttat gcctggcgac aacgtaacaa tggaagttga attaatccac
    30421 ccaatcgcta tcgaaaacgg tactaaattc tcaatccgtg aaggcggacg tacagttggt
    30481 gccggtgtcg ttacagaaat caaagcttaa ttcacttaag ttttaaagta aagcaacatt
    30541 tattcggacg taatcgctcg gaacgaaggt cttaggatct ttgttccgag cttttttatt
    30601 tattgcagga tcaggaaaaa agacaggagt attataaata gaagaaacac gaaataaaag
    30661 agtcagtatt ttctaaatga aactttatga aaacaaaatg ttttttacaa gaaaaagcct
    30721 tgctttgtga gtttatatat attataatga caaaggtgcg tttactttag tgaattgcac
    30781 agacgtaatc agaatgattt cgtcggctaa gaaacgagag gttgcgacac gcccggacgc
    30841 tttgccacga acgagcgtga cggaaatttt cgtggagcta tgtctacttt tcaaaatagg
    30901 cgaaggaggg aacaagatgg caaaacaaaa aattcgtatc cgtttaaaag cgtatgaaca
    30961 ccgtatttta gatcaatcag cggataaaat cgtggaaact gcaaaaagaa ctggagctag
    31021 cgtgtctggt ccaattccat taccaactga acgcagtctt tacacaatca tccgtgcgac
    31081 tcataaatac aaagattcac gcgaacaatt cgaaatgcgt acacacaaac gtcttatcga
    31141 cattgtgaac ccaacaccaa aaactgttga tgctttgatg aagctagact taccatctgg
    31201 tgtaaacatc gaaatcaaat tataaaacta aaacaaaaat aatggaggtg tactcatgac
    31261 caaaggaatc ttagggaaaa aagtgggaat gacacaaatc ttcactgaat ctggtgaatt
    31321 aattccagta actgttgtag aagctactcc aaacgtagta ctacaagtga aaacaatgga
    31381 aacggatggc tacgaagcta ttcaagttgg ttaccaagat atgcgtgaag ttttatcaaa
    31441 caaacctgcg aaaggtcatg ttgcaaaagc aaacacggct cctaagcgct tcattcgtga
    31501 attcaaaaat gttgagctag gagaatatga agtaggaaaa gaaattacag tagatgtttt
    31561 ccaagcagga gacattattg atgtaacagg tactacgaaa ggtaaaggat tccaaggggt
    31621 tatcaaacgc cacggacaaa gccgcggacc aatggctcac ggttctcgtt accatcgtcg
    31681 tcctgggtca atgggtccag ttgcacctaa ccgtgtattt aaaaacaaac gtcttgctgg
    31741 ccgtatgggt ggcaaccgcg taactatcca aaacttggaa gttgtacgtg tcgatgcaga
    31801 aagaaatgtt atcttgatca aaggtaatgt tcctggagct aaaaaatctt taattactat
    31861 caaatcagct gtgaaagcta aataattgta ggaagaaagg aggaactaag gaatgccgaa
    31921 tgtagcatta ttcaaacaag atggaagcca aaacggtgaa atcacactta acgaagaaat
    31981 cttcggaatt gaacctaatg aaagtgttgt ttacgatgca atcgtaatgc aacgtgcgtc
    32041 attaagacaa ggaacacacg cggttaaaaa ccgtagcgct gttcgcggcg gcggacgtaa
    32101 accatggcgt caaaaaggaa caggtcgtgc acgtcaagga tctatccgct caccacaatg
    32161 gcgtggaggt ggcgtagtct ttggaccaac accacgttct tacagctaca aacttcctaa
    32221 aaaagttcgt cgtttagcaa tgaaatctgt attgtcagaa aaagttgctg aaaacaactt
    32281 ggtagcaatc gaaggcttga acttcgacgc accaaaaaca aaagaattca aacaagttct
    32341 tgctaactta tctatcgact ctaaagtatt ggttgttcta gaaaaaggta acgactttgc
    32401 tgctttatca gcacgtaact taccaaacgt ttctgtagta acttctgata atgtgagtgt
    32461 gctagacgtt gtatcaaata caaaagtgtt agcaacacaa actgctctta ctcaaattga
    32521 ggaggtgctt gcataatgaa cttactagac gtaatcaaac gcccagtgat cactgaaaaa
    32581 tcaatgcttg ccatggatga caagaaatac acttttgaag tggacactcg cgcaaacaaa
    32641 actttagtaa aacaagcggt agaagctgct tttgacgtta aagtcaaaaa cgtgaacatc
    32701 gtgaacgtac gtgcgaaatt caaacgtatg ggcaaatatg caggatatac aaaaaaacgt
    32761 cgcaaagcga tcgttacatt gactgaagat tcaaaagaaa tccaattatt cgaagctgct
    32821 gaataagcac taatagataa ctcattaaat taggagggaa aaacgtggcg attaaaaagt
    32881 acaaacctac ctcaaatggt cgtcgtaaca tgacaggttc tgattttgct gaaatcacaa
    32941 catcaacacc tgaaaaatca ttgttacaac cattgaaaaa ccatgctgga cgtaacaaca
    33001 acggccgcat cactgtacgt catcaaggtg gcggacacaa acgccaatat cgcgtgatcg
    33061 acttcaaacg taacaaagat aacgttgttg caactgttca aacgatcgaa tatgatccaa
    33121 accgttcagc taacatcgcg ttagtacact atgaagatgg agtgaaagct tacatcttag
    33181 cacctaaagg actagaagtg ggtatgaaac ttgtttcagg tccagaagca gatatcaaag
    33241 tcggaaatgc tcttccatta gaaaacattc cagttggtac tgttatccac aacattgaaa
    33301 tgaaacctgg taaaggtgga caattgatcc gttctgctgg tacaagtgct caagtacttg
    33361 gtaaagaagg caaatacgta ttgatccgct tgaactctgg tgaagttcgt atgatcttag
    33421 ctgcatgccg tgctacaatc ggttctgtag gtaacgaaca acacgaatta atcaacatcg
    33481 gtaaagctgg acgctctcgt tggatgcgta aacgcccaac tgtacgtggt agcgtaatga
    33541 accctaatga tcacccacac ggtggtggtg aaggtaaagc tcctatcgga cgtaaagcac
    33601 cagtttctcc ttggggtcaa ccagctcttg gttacaaaac tcgtaacaaa aaagctaaat
    33661 cagacaaact tattgttcgt cgtcgcaaaa ataaataatt actttgacca tgtgtcgcac
    33721 attttgagag gaggttcacc atgggtcgta gtttaaagaa aggacctttt gtcgatgagc
    33781 atttaatgaa aaaagttgaa gctcaagcag gggttgaaaa gaaaaaagtt atcaaaactt
    33841 ggtcacgccg ttcaacagtt ttcccaagtt ttgttggata taccatcgca gtttatgatg
    33901 gacgtaaaca tgtaccagtt tacatccaag aagacatggt aggacacaaa ttaggtgaat
    33961 ttgcacctac aagaacttat cgtggacatg ctgctgacga taagaaaacg aaacgctaat
    34021 ttgaggggag gataaatcca aatggcagaa caaatcacat cagctaaagc aactgcaaaa
    34081 acagttcgca cttcacctcg aaaagcccgt ttagtaattg accttatcag aggtaaaagt
    34141 gtcgcagatg caatttcaat cttgaaattc acaccaaaca aatctgctgg aatcattgaa
    34201 aaagtattga tgtcagcagt tgcgaatgca gaaaataact ttgacttaga tgttgaaaac
    34261 ttggtagtaa gcgaagcttt tgttaacgaa ggacctacaa tgaaacgttt ccgtcctcgt
    34321 gcaaaaggat cagcttctcc aatcaacaaa cgtacaagtc atatcacggt agtcgtatca
    34381 gaaaaataag gagggataat cagtgggtca aaaagtacat ccaattggaa tgcgtgtagg
    34441 catcatccgc gactgggatg ctaaatggta tgctgaaaaa gagtatgctg agttcttaca
    34501 cgaagattta agaatccgta aatttatttc aactaaactt gctgatgctg ctgtatcaac
    34561 agttgaaatc gaacgcgcaa caggtcgcgt aaacatttca attcacacag ctaaaccagg
    34621 tatggttatt ggtaaaggcg gttctgaagt cgaaagccta agaaaagaat taaacaaatt
    34681 aactggtaaa agaatccata tcaatatcgt ggaaatcaaa aaaccagatc tagatgcaaa
    34741 attagtaggt gaaggaatcg cacgtcaatt agaaaaccgt gttgctttcc gtcgcgctca
    34801 aaaacaagcc atccaacgct caatgcgtgc tggcgctcaa gggatcaaaa ctcaagtatc
    34861 tggtcgtcta aacggagcag atatcgctcg ttcagaagga tactcagaag gaactgttcc
    34921 tcttcatact ttacgtgcgg acattgatta cgcatgggaa gaagcagata caacatacgg
    34981 aaaactagga gttaaagtgt ggatctatcg tggagaaatt cttccaacta aaaaaaacac
    35041 tgagaaagga gggaaataat catgttagta cctaaacgtg taaaacaccg tcgtgaattc
    35101 cgcggaaaaa tgcgcgggga agctaaaggc ggaaaagaag tagcattcgg tgaatacggt
    35161 ttgcaagctg ttgattcaca ttggatcaca aaccgccaaa tcgaagctgc tcgtatcgca
    35221 atgactcgtt acatgaaacg tggtgggaaa gtatggatta aaattttccc tcacaaatct
    35281 tatactgcca aagcaattgg ggtacgtatg ggttctggta aaggggcacc tgaaggatgg
    35341 gttgcaccag taaaacgtgg taaaatcatg tttgaaatcg caggcgttcc tgaagaagta
    35401 gctcgtgaag cgttacgtct agcttctcac aaattaccaa tgaaaactaa gatcgtaaaa
    35461 cgtgaggaaa tgggtggtga atcgaatgaa ggttaaagaa atcagagaat taaccactgc
    35521 cgaaatgctt gatcaagaaa aacaattaaa agaagaattg tttaatctta gattccaatt
    35581 agcaacaggt caattagaaa acactgcacg tattaaagaa gtacgtaaat cgattgcacg
    35641 catcaaaact gtgttgcgtg aacaagctaa gtaattatgg aaggaggcca ttaagcgtat
    35701 gactgaagga agaaatcaac gcaaagttta tcaaggtcgc gtggtttcag acaaaatgga
    35761 taaaacaatt accgttgctg tcgaaacaaa gaaaaaccac cctatctatg gcaaacgcat
    35821 gaactattct aagaaataca aagtgcatga tgaaaacaac acagcaaaag ttggcgacat
    35881 cgtgagaatt atggaaactc gtccattatc agctacaaaa cgtttccgtt tgttggaagt
    35941 agtcgaagaa gcagttatta tctaataaca cgagattttc ctatatagat tgaatgcaaa
    36001 atctgaaagg aggatacaca acgtgatcca agcagaaagt cgtttaaaag tcgctgataa
    36061 ctcaggcgca cgtgaaattt tgacgatcaa agtccttggt ggatctggtc gtaaaactgc
    36121 taacatcggt gatgtgatcg ttgctacggt taaacaagca acgccaggtg gggttgtcaa
    36181 aaaaggtgac gtcgttaaag ccgttatcgt tcgaacaaaa tcaggagctc gtcgtacaga
    36241 cggttcatat attaaatttg atgaaaatgc tgcagtgatt attcgtgatg ataaaagccc
    36301 tcgtggaaca cgtatctttg ggccagttgc acgtgaacta cgtgaaaaca acttcatgaa
    36361 gatcgtttca ctagcaccag aagttttata atcttgagac acttatcaaa ggaggtgcga
    36421 aacagttatg tttgttaaaa aaggcgataa agttaaagtt atcactggaa aagacaaaaa
    36481 caaagaaggc gttgtactag cagcgttccc gaaaaaagat aaagttattg tcgaaggtgt
    36541 aaatgtcgtt aaaaaacacc aaaaaccttc tcaagctgct cctcaaggtg gaattgttga
    36601 gatggaagcg ccaattcatg tttctaacgt gatggtggtt gactctactg gtgtagctgg
    36661 ccgagttggc tacaaagaag tagacggcaa aaaagtccgt gtttctaaaa aaaccggtga
    36721 agttttagat aaataaaagt ttaaggaagg agggtcttac tgaatgaacc gcctaaaaga
    36781 aaaatatctt aaagaagtaa ctccatcatt gatggaaaaa tttaactata gctctgttat
    36841 gcaaacacct aaagttgaaa aaatcgtcat caacatgggt gttggtgatg cggtatcaaa
    36901 cgctaaaaac ttagataaag cagttgaaga attaactttg atcactggtc aaaaaccaat
    36961 gattacaaaa gctaaaaaat caatcgctgg attccgttta cgtgaaggaa tgccaattgg
    37021 tgcaaaagtt acattgcgcg gagaaagaat gtacgaattc ttagacaaat tggtttctgt
    37081 ttcactacca cgtgtacgtg acttccatgg tgtaagtaaa aaagcctttg acggtcgtgg
    37141 aaactatact ttaggtatta aagaacaatt gatcttccca gaagtagatt atgatttagt
    37201 agataaagta cgtggtatgg acatcgttat tgtaacaaca gcaaactctg atgaagaatc
    37261 tcgtgagttg ttgacacaat taggcatgcc attccaaaaa taattaaagg aggcgaacta
    37321 cgtggctaaa aaatcaatga ttgctaaaaa caaacgtcct gcaaaatttt caacacaagc
    37381 ttatactcgt tgcgaacgtt gcggacgtcc acattcagtt tatcgtaagt tccatctttg
    37441 ccgtatttgc ttccgcgaac ttgcctataa aggtcaaatt cccggcgtga agaaagctag
    37501 ctggtaaaaa gtaaattcgc ataagaagga ggtaaaagat caatggtcat gacagatcca
    37561 attgcagatt ttctaactcg tatccgtaac gcaaacatgg ttaaacatga gtctttagaa
    37621 gtacctgcat caaaaattaa acgtgacatc gctgaaatct tgaaacgtga aggtttcgtt
    37681 cgtgatgttg aatacatcga agatgacaaa caaggcgtga tccgtgtttt cctaaaattt
    37741 ggtaaaaacg gcgaacgtgt tatcacaaac ttaaaacgta tctctaaacc aggtttgcgt
    37801 gcttatgtca aagctgacga agtaccaaaa gtattgaacg gtttaggtat cgcaatcatt
    37861 tcgacttctg aaggtgttgt cactgataaa gaagctcgtg aaaaaaatat cggcggcgaa
    37921 gttatcgctt acgtatggta atcaagtaga atctacaagg aggtgtcttt aagtgagccg
    37981 tatcggaaat aaagtcgttg ttatccctga aggagtaaca gttactcaag acggaaacaa
    38041 cgttacagtt aaaggaccaa aaggtgaatt gactcgtact ttttcagcag atatcaaaat
    38101 gaatatcgaa ggaaacgaag taactttcac tcgtccaaac gacagtaaag aaatgaaaac
    38161 aattcatgga acaactcgtg cgaacttcaa caacatggtt gtaggtgtca gcgaaggttt
    38221 ccaaaaagcg ttagaactaa tcggggttgg gtaccgtgca caattacaag gatcaaaact
    38281 tgtattgaac gttggttact cacatccagt agaaatcaca ccaccagctg gagtaactgt
    38341 tgaagtacca gctaacacac aagtaattgt taaaggtgcg aacaaagaag aagttggcga
    38401 attagctgca aacattcgtg gaactcgtcc tccagaacct tataaaggta aaggtattcg
    38461 ttatgttggc gaatatgtac gccgtaaaga aggtaaaact ggtaaataat cgtttagaaa
    38521 aattgcatag aagccagcag caggaaaaag gcatttggct gaagtttacc ttcaaaaaaa
    38581 tacattttta cttgtgccgc agcttctatt tttcgaaacg tatttactgc ttgaaatagt
    38641 agtacaataa aaataaagag gtgacaattg tgattacaaa accagataag aacaaaacac
    38701 gtcaaaagag acatcgtcgt gtacgtaaca atatctctgg tactgctgag cgcccacgct
    38761 tgaacgtttt tcgttctaac aaaaacatct acgctcaaat tattgatgac gtagcgggtg
    38821 taacgctagc aagtgcctct accttggata aagaaatttc aggtggaaca aaaacagaag
    38881 cagcacaagc tgtcggtaaa ctagttgctg aacgtgcagc tgaaaaaggc attaaagtag
    38941 tagtctttga ccgtggtgga tacctttacc atggccgtgt gcaagcttta gctgaagctg
    39001 ctcgcgaaaa tggactagaa ttttagaaga aggaggaata ccattcatgg tttatatcga
    39061 tccaaaacat ttggaattag aagaccgcgt tgttgcaatt aaccgtgtaa caaaagttgt
    39121 taaaggtgga cgtcgtctac gttttgctgc tttagttgtt gtcggtgaca aaaacggaca
    39181 cgtaggattt ggtacaggta aagctcaaga agttcctgaa gcaatccgta aagcaattga
    39241 agatgcgaag aaaaacttag ttgaagtacc tatggttggt tcaacaatcc cacacgaagt
    39301 aatcggtgct tttagtggtg gtagaatcct aatgaaacct gctgtagaag gttctggggt
    39361 tgctgctggt ggaccagttc gtgccgtatt agaattagct ggggtagcag atatcacttc
    39421 taaatcttta ggctcaaata caccaatcaa cgttgttcgc gcaacagttg aaggtttgaa
    39481 acaattgaaa cgtgcagaag aagttgcaga acttcgcggc aaatcagttg aagaattaat
    39541 cggataagga ggacaacaat aatggctgaa ttaaaagtta ctttaaaacg cagtattatc
    39601 ggacgtcctc aaaaccaacg cgatacagtt aaagcgttag gtcttacaaa gattaacagt
    39661 tcagtggtta agccttctaa tgaagcaatt aaaggcatga tcaatactgt ttctcaccta
    39721 gtggacgttg aagaaattta atttagaaaa atcataacta gaacattaag gaggtgccaa
    39781 acctatgaaa cttcatgaat taaaacctgc tgaaggttca cgccaagtac gtaaccgtgt
    39841 tggtcgtggt acttcatctg gtaacggaaa aactgccgga cgcggacaaa aaggacaaaa
    39901 agctcgttca ggcggcggtg tgcgtttagg atttgaaggg ggacaaacac cattgttccg
    39961 tcgtttacca aaacgaggat tcacaaacgt gaaccgtaaa gactatgcag tcattaatct
    40021 tgatgtattg aaccgctttg aagacggagc tgaagtaact cctgttgctt tagttgaagc
    40081 tggaatcgtg aaaaacgaaa aagctggaat caaagtatta gctaatgggg aactaaacaa
    40141 gaaattaact gtgaaagcag caaaattctc taaagcagct caagaagcaa ttgaagcggc
    40201 tggtggatca atcgaggtga tctaatgttt agactattaa aagatgcttt taaagtaaaa
    40261 gacattagat cgaaaatcct atttactgta tttgtgttgt ttgtatttcg cctaggtgca
    40321 catattactg taccaggcgt aaatgctgct tcattgcaaa acctttcttc tttgccattt
    40381 ttcaacatgt tgaacttggt aagtggtagt gcgatgcaaa acttttccat tttctcaatg
    40441 ggggtttcac catacattac tgcttctatc gtcattcagc ttcttcaaat ggacatcgtg
    40501 cctcgatttg ttgaatggtc gaaacaaggg gaagttggtc gtaaaaaact gaatcaagcg
    40561 actcgatatc tgacattagt attggcattt atccaatctg tcggtatcac tgctggattc
    40621 aatcaatacg ctcaattagg tttcgtgaat aatcctaacg tagcaactta cgtaacgatc
    40681 ggtttgattc taacagccgg tacgatgttt gttacttggc taggagaaca gatcacagaa
    40741 aaaggtatcg gaaatggcgt atcaatgatc atttttgcag gtatcatttc tagattgcct
    40801 gaaagtatca gagaaattta tgaagattac tttataaata ttgatccttc agacatatgg
    40861 aaatctgcta tttttgtggc cattttacta gtagcggtct tgttgatcgt gacattcgta
    40921 acatttttcc aacaagctga acgcaagatc ccgatccaat atacgaaacg cgtagctggc
    40981 gcgcctacaa gcagctatct gccgttgaaa gtaaatgcag ctggagttat tccagttatc
    41041 tttgctagtt cgtttattgc tacgccaaat gctgttttac aagcattgag cggtagattc
    41101 ggttctgaaa actggtacaa agtgatgatg gagatcttta actataatac agcacctggt
    41161 gctacgattt atacgattct gatcgttgcc ttcactttct tctacgcctt tgttcaagta
    41221 aaccctgaga aattagcgga aaacttgcaa aagcaaggaa gttatatacc aagcgtacgc
    41281 cctggtaagg ggactgaaga gtatgtctca agattactga tgcgtttaag tacagttggt
    41341 gcagtcttcc ttggtttagt ggcattgctt ccaatcattg ctcaaatggt ttgggatctt
    41401 ccacaatcaa tcggattagg cggtacaagc ttactgatcg ttatcggtgt agctttagaa
    41461 actgcgaaac agttagaagg cttaatgctg aaacgtaaat atgttggatt cattgagtaa
    41521 gaaagcgtgt tgaggtttcc cctcaacaca cgttctcaca catttattag gagggaaaac
    41581 aatgaacctc attttaatgg ggctgccagg cgcaggtaaa ggaacacaag ctgaaaaaat
    41641 cattgatgct tatggtattc cgcacatctc aacaggagat atgttccgcg cagcgatgca
    41701 aaacgaaaca gctcttggcc tggaagcaaa gtcttatatg gataaaggtg cattagttcc
    41761 tgatgaagta acaaatggaa tcgtgaaaga gcgactagct gaaccagata cagagaaagg
    41821 cttcttatta gatggctttc cacgtacgct agatcaagca aaagctctgg acgcaatgct
    41881 aaaagatttg aataaaaaaa ttgatgctgt catcgatatc catgttggtg aagaaatctt
    41941 ggtcgaacgt ctagccggcc gatttatctg cagcaattgt ggagcaactt accataaaat
    42001 tttcaaccct acaaaagttg aagacacatg tgatcgttgc ggtgggcatg aattctatca
    42061 aagagaagat gataaacctg agacggttaa aaatcgtctg gctatcaaca tcaaaaatag
    42121 tgaaccaatc ttggcttatt ataaagaaca aggtttgcta aacactattg atggtgctcg
    42181 tgaaatcgat gctgtatttg cagatgtaca aaaaatcatt gaaaaatagc acgattgccc
    42241 gtagccgact tgcattatgc agttactctt gtcaagttca ataaattatg atagaatatg
    42301 tcagtccgac ttctagagaa tcctctagat gatccatttt gagaattttg aggtgggaac
    42361 tgcagtttcc gccattttat cgtgtgaaaa tgcgaaacaa gtacaaggag gtactgtgcg
    42421 tggcaaaaga agatatgatt gaagtcgaag gtacagtcgt cgaaactttg ccgaatgcaa
    42481 tgtttaaagt tgaactagaa aacggacacc aagttcttgc tactgtttca ggtaaaattc
    42541 gtatgcatta catccgtatc ttacctggtg acaaagtaac ggttgaattg tctccatacg
    42601 atcttaaccg tggccgtatt acttatcgct ttaaataatt gtactccgta aaactacagg
    42661 aggtattatc atgaaagtaa gaccatcagt aaaaccaatg tgcgaacatt gtaaagtaat
    42721 tcgtcgtaaa ggacgcgtta tggtgatttg cccagcaaat ccaaaacata aacaacgtca
    42781 aggataattg gaggtgctat aaatatggct cgtattgcag gagtagatat tcctcgtgat
    42841 aaacgtgtag tagtttcact tacttatatc tatggtattg gtaacactac tgctaaaaag
    42901 atcttagctg atgctggtgt atctgaagat gttcgcgttc gtgaattaac gaatgaacaa
    42961 acagatgcta tccgtgcaga agtagataaa ttaaaagttg aaggggatct tcgtcgtgaa
    43021 gtgaacttga acatcaaacg tttgatggaa atcggttctt accgtggaat ccgtcatcgc
    43081 cgtggattgc ctgttcgtgg acaaaacacg aaaaacaatg cacgtactcg taaaggccca
    43141 gctcgcgcta tcgctggcaa gaaaaaataa ttcttaagtg aaggaggtta aaacttcatg
    43201 gcagcaaaaa aagtgaatcg taaacgccgt gtgaagaaga atatagaagc aggtattgca
    43261 catatccatt ctacattcaa taacactatc atcatgatca ctgatactca cggaaatgca
    43321 ttagcgtggt catcagctgg ttcattaggt ttcaaaggaa gcaaaaaatc aactcctttt
    43381 gccgctcaaa tggcagcaga aactgctaca aaagcagcaa tggaacacgg attaaagact
    43441 gttgaagtaa cagttaaagg acctggttct ggacgtgaag cagcaattcg ttcattacaa
    43501 gctacaggtt tagaagtgac tgcaattcgt gacgtgactc cagttcctca taatggtgcc
    43561 cgccctccaa aacgccgtcg tgtttaatga gtgccgctca ttttgagttt tatcagtaac
    43621 gtcattgaac aagacacttt tcgttttgaa aggggtaaag ataagaatga ttgagttcga
    43681 aaaaccaaga atcgcaaaaa ttgatgaaga aaaagattat ggcaagttca tcgttgaacc
    43741 tcttgaaaga gggtatggga ctactttagg gaattcccta cgtcgtattt tattatcttc
    43801 tttgccaggt gctgccatca ctaatattca aatcgatggt gtactgcatg aattctctac
    43861 catcaaaggt gttagagaag acgtcactca aatcatcttg aacattaaag gcttagcgct
    43921 gaaaatgtat ggccaagaag aaaaaaccct tgaaatcgat attaccggac ctgctacagt
    43981 aactgctggc gatattatcg ttgatagtga tgtagaaatt cttaacaaag atatgtacat
    44041 ctgtagtgtc tctgaaggag ctacgttcca tgctcgctta acagtgaaac ctggacgtgg
    44101 ttatgttcaa gcagatgaaa ataaaaaaga agatatgcca attggcgttc ttccagtcga
    44161 ttcaatctac acacctgttc gtcgtgtgaa ctatcaagtt gagaacacac gtgttggaca
    44221 ccgtgaagat tttgataaat tgacgatgga gatttggaca gatggttcaa ttgaaccgtt
    44281 ggaagcaatg agtttgtctg cgaaaatcat gactgaacat ttggatattt ttgtgaactt
    44341 aactgatgaa gcaaaaaatg ctgaaatcat ggtcgaaaaa gaagaaacac aaaaagaaaa
    44401 aatgttggaa atgacgatcg aagagttaga cttgtctgtt cgctcttaca attgtttgaa
    44461 acgtgcagga atcaatactg tacaagaact tacaaataaa tctgagcctg aaatgatcaa
    44521 agtccgtaac ttaggacgta aatcattaga agaagttaaa gcaaaattgc acgacttagg
    44581 tttaggttta cgtaaagaag attaaaacct tttacgaagg agggaaacca acgtgagtta
    44641 tcgtaaacta ggacgcacat ctagccaacg taaagcgatg ttgcgtgatt taacaactga
    44701 tttattaatc aacgaacgta ttgtgactac tgaagctcgt gcgaaagaag ttcgctcaac
    44761 tgcagaaaaa atgatcactt taggtaaacg cggagatttg catgcacgtc gtcaagctgc
    44821 ggctttcgta cgtaatgaag ttgccagcgt gcgtgaagaa aatgaggaca tcgtcattga
    44881 atcagcttta caaaaactgt tcaacgatat tgcacctcgt tacgcagaac gtcaaggcgg
    44941 atacacacgc attttgaaga cagaaccaag acgcggtgat ggtgcaccaa tggttgtctt
    45001 agaacttgtc taaaatcaca ctaataacat cactttatag atgattcttt tagagtgtta
    45061 tgatgttgga agatattttt ccgagtctag ctcagcgctg ctcctcaagc gaatatcgct
    45121 tggggagtaa gcactcatca taaagtgttt ttttatacct tcaattacct gtcatgacag
    45181 atatgtttga aggcataaaa aaacatttta agcgagaaat aattgaaaat tttgtctttt
    45241 tttgatagtg ttagtaggaa ctttaggatg aagaaggagt aatcatggag ccaattattg
    45301 aattagaaaa gataaattat aaataccagc cagatgatct tcgccccgca ttgaaagatg
    45361 tctcctttac aattgataaa ggtgagtgga tcgctattat tggacacaat ggttcaggaa
    45421 aatcgacact tgccaaaacg atcaatggat tgcttctgcc agaatcaggg atcgtgaaag
    45481 tgggaaatca aatattggat gaagaaaata tttggacgat ccgacagatg gttggaatgg
    45541 tttttcaaaa tccagacaat cagtttgttg gttcgacagt agaagatgac gttgcttttg
    45601 gtcttgaaaa tcaagggatt cccagagaag aaatgctagt gcgtgtgaaa gatgcacttg
    45661 agaaagttag aatggctgag tttgcttcac gcgagcctgc tcgtttatca ggagggcaaa
    45721 aacaacgtgt tgccattgcc ggcgtggttg ccttacgacc tgatatcatt attttagatg
    45781 aagcaaccag tatgctagat ccagaaggtc gtgaagaagt gatctctacg atcaagaaga
    45841 tcaaagaaga aagtcaattg accgttatat ctatcactca tgatattgat gaagcagcta
    45901 atgccaatcg gatactagtg atgagacaag gcgaacttgt ccgtgaaggt acaccaaaag
    45961 aaattttttc tgctggtcct gaactgatcg acttaggtct agatctacca tttcctgaaa
    46021 aactgaagag cgcactgaaa gaacgtgggg ttgatgtgcc cagtgaatat atgacagaag
    46081 aaaggatggt ggattggtta tggacatccg ttttgaacaa gtagacttca cttatcagcc
    46141 gaatacacca tttgaacaaa gagccttatt tgacatcaat atgacgatca aagaaaacag
    46201 ttatactgca ttagtagggc ataccggaag cgggaaatca accttacttc agcatttgaa
    46261 tgcgcttgtt aagccaacaa gcggtacagt ccatattgga gaacgagata ttcagccgga
    46321 tacggataat aagaatttaa agcccatccg aaaaaaagtt ggcatcgtct ttcagtttcc
    46381 agaagcacag ctattcgaag aaacggtagc aaaagacatt gctttcggtc ctaaaaactt
    46441 tggtgtcagc gaagaagaag cactagtcct agcaaaagaa acattagaac aagttgggct
    46501 ggatgaaagc tatttggaac gttcgccatt tgaactttca ggagggcaaa tgcgtagagt
    46561 agcaatcgct ggtgtgcttg ccatgaggcc ggaagtactt gtattggatg aaccaacggc
    46621 aggacttgat ccccagggca gaaaagaaat gatggagatg ttttggcgtc ttcataagga
    46681 acagcagatc actattgtat tagttacgca tttaatggat gatgtagcca attttgcaga
    46741 ttatgtctat gtgttggaaa agggacgaat cgttaatagc ggggagccgc aagaggtctt
    46801 tcaaaacatt gaatggctaa aagaaaaaca actaggcgta cctactgcca ccgagtttgc
    46861 agaagaatta atggctaaag ggatgaactt tgctaccttg cctttgacag ctgaagaatt
    46921 agcagacgct atcgtccatt atgctggagg aaatgcccat gatgaataaa ttgatatttg
    46981 gtcgttatat gcctggagat tccttgatcc atcgattgga tccccgagct aaattattag
    47041 ccagttttta ttttatcgga atcatttttt tagcaaataa ttgggaaacg taccttttgt
    47101 tggcattttt cacattactt tctgtcttct tgtcaaaagt agatttgaaa ttttttatcc
    47161 gaggcattcg cccattgatc tggctaatcc tcttcactgt agctttgcag gtcttgttta
    47221 caagtggcgg agaaacttat tggagttggg gtgttttcca tatcactgaa tttggtgtga
    47281 tgaacggcct ctttattttc tgtcgattcg tgttgatcat ttttatgtcg actctactca
    47341 cgcttactac accgcctttg gaattatcgg atgcgattga gtacttgctt cgtccattga
    47401 aagccgtacg gttcccagtc cacgaaattt cattgatgct gtcgattgct cttcgttttg
    47461 tgcctacatt gatggacgaa acagaaaaga tcatgaacgc tcagcgcgct cgcggtgttg
    47521 attttggtga aggaaaccta gttcagaaaa tgaaagcagt cattcctttg ctgattcctt
    47581 tatttgtcag cagcttcaac cgtgcggaag atcttgcgac tgctatggaa gcaagaggct
    47641 acaaaggtgg ggaaggaaga acgaaatatc gtgtattgca ttggcataat agagacacga
    47701 tggttatcat tgcttttgta ttattaactg tgctactgat ctttttaaga ggataaacgt
    47761 tcagtgggcc gctatctatt cttttcttgc tgatctgttt gcaagaaagg atgcaagcag
    47821 tgtatgacaa gaaatattag ggtctgtggc agactaaggt cacaggcctc tttcttttat
    47881 ctgaaaagaa agaacgaaaa aattttatag aaaaatcatt attccagata accttttagg
    47941 aacaaaggag agaaaaacat ggtacgttac aaagcaatca ttgcgtacga cggaacaaat
    48001 tttaatggat tccaaaaaca gccaaatggg cgtactgttc aagaagaagt agaaaaaaca
    48061 ttacaaaaaa tggcaaatgg aaaagaaatc acggtctttg gttcgggaag gacagatgcc
    48121 ggagtacatg cgatcgggca agtaatccat tttgattatc cagaggagcg tccgttagaa
    48181 cgaatgcgtt tcgcgctaga tacccagtca ccagaggata ttgctgtaag acaagtagaa
    48241 attgtttcag aagacttcca cgcaagatat ttggtcaaag aaaagacgta tcaatttcga
    48301 gtggatatag ggaaaccacg cagtcctttt cgacgccatt atgcaagtta ttttccttac
    48361 ccacttgatt tggaaaaaat tcagcgggcg cttcctgatt tattagggac tcacgatttc
    48421 acctcttttt gtgcatcagg aagctcgata gaggataaaa tacgtacgat ctacgaggct
    48481 aagatggagg taaatgaaac aaaagacgaa ttgttgttta catttagggg aaatggcttc
    48541 ttgtataaga tgatacggat cttagtagga acgcttttga aaattggcaa tggccgattg
    48601 cctgaagata gtatcccaga tattattgcg aaaaaagatc gtaatgcagc aggacctaca
    48661 gcacaccctg aaggacttta tttgtatgaa gtgaaatatg aataagaggt tatgatagaa
    48721 gtggtcagct tcaagaaata agaaggtatt tacgaaaatt acttctcaaa attttgcaaa
    48781 atttcggctt attttcgaag aagctacttc tggaacaccg tttaaggaag aggtcgtgaa
    48841 atcagcgttt tgacctgagt attagagaaa caaacgggaa aatagctcct catattttgc
    48901 cgtttgttga gctaataccg aaggtcagct gattgaacac cgtttaagaa agaggtcgtg
    48961 agcctgtcat ttaactctga gtcacaaaga gcaatttcaa aaaacagctt ctcatctttg
    49021 atgaatatcg tgacttgtgg acgaggcgtt gataagtgaa tcatcttttt gttacctatt
    49081 ttttctgtaa ccaaaaaacg atggaacgtt gttttgattg cccttggtgc ggacagtctg
    49141 aacaggttcc atcgtttctt tattttctac gtcttcttct gtgtgtgttt cgtggttgtt
    49201 cttctattgc tggatcaatc gtgccataaa aggggcgatt gcggtcaagg taccagacat
    49261 aaagaataaa caatgcaata cataggacaa aaaggattgc acctatcgta aatccttcag
    49321 gcaagtaact gaaagtgaca gtatgtttac ctgctggaac ttttatcatc aagaatgcgt
    49381 ctttgaaatt gctgaccttg actggtttcc catcaatttt agctttccat cctttgtcat
    49441 aaggaatagt tgtcaccaac atggaatctt cagcggtatt tacagtccca gaagcttttc
    49501 tgccagtggc ttccatttcg acaccttttt ctttgatctg attcattgcg gcttgatagg
    49561 ctacaacatc tagaccaacg actttaggct ccatgaaact tatttctttc gtcccataaa
    49621 aacttgcagt aaatgtcact gttgtctctt gaggataata gccaagatca tagtattgac
    49681 cagaaatgtt gatttgcgtt tttcgcgatg taccattgac agtgatcgtc gcactagaac
    49741 tttctaattg cgcaaaattg gttgggaaca aacttaagta agcttgtgta tttgcaggca
    49801 catggacttc ccaagtgagc tcttttggct ggttatctgc tgtttctgag taagtgacgc
    49861 cagtcgttgt ctttgtgatc gtcgtattca actgattctt caaagtaggt gtatagaatg
    49921 taaaatactg ttcatttaga ccagacaatg tattgatcaa gtttgtctga ctggtcaaat
    49981 tatctgtcac tggctgctca acatcattaa cggacaacgg tgcagtaaat gctagtggca
    50041 atgcattgac attctgatac agtgtatagt cgccgctttg accagcttgg cggaagccat
    50101 atttactgaa cgtgctttcg tttttagaaa tgttatattt gattcctgta aacccatcca
    50161 tcagcaaagt attattgtta taacggatat tcaaatttgt ccctcttgaa cggaaaccta
    50221 atttatccag gtaagaggaa gaattacgat ttcttataga agaaaacaaa ctgataccac
    50281 tgtaaccata gttgatcgaa tcgtttgcag atactggatc cagattttcc aagcggtaaa
    50341 acgagtcgga atcttttttt gtttcattta caagagcttt caagtcagga taaggatcag
    50401 tatataaact gcgggaagca taattccaat catcaagaat gccatggatc atactgttcg
    50461 tattgaccag tgcttcagca gacatgatca ataataacaa tatactcaga tgattgaatg
    50521 aaagtttttt atgctgataa aatcccacag caaaagcata aatccctaag aaaaccactg
    50581 tcaatacaaa ggaagtcatc gtcacatagg tgtagcttcc ttcaggtttg atgccccatg
    50641 ccaccgcaaa gagagcagct acgaccaaaa tgattcctaa caacagccca cgatcgtctt
    50701 gttctatctt ttcccatcct tttcctgcaa gcaggagcac taagaaagag aacagatagg
    50761 cataacggaa taaaaacata ttcggtgcat gcataccatg ccagaacaaa ttcaatggaa
    50821 caagataaaa acttgcgata agtatggcga aaagactgcc gtacaaaaat ttatttttca
    50881 acggtacttt ccgactggca aaataaaaca gacagaggac taatggtagc agacctgcgt
    50941 aaacgaacgg aatcgatccg tattttgtcg tgtcataaac accaatcata tttttcatga
    51001 ttagatccag ataagaagtc gcttctgttt tcaacgtagt gatctgactc agtgcctcgc
    51061 catttgaccg aagatccagc actgctggca atacaatgat cattgaagcg ccgcctgcca
    51121 gtaaagaagt gataccataa ggaacaatcg tttttttata ttctgaccag tttgtcaata
    51181 gacgggcgat aaaatataag aaagaaaata cgccaatcat aaaacccata taaaaactgg
    51241 ataaaaacaa gagtaaataa ctgataaata aaagtttcgg ccgtttaaga tccataacac
    51301 gatgaatccc caaaatcact aatggaagat aaaaaaatgc atccagccac atgatgatct
    51361 ccgaatgtgc agtgataaat gagatcaatg cgtaactgac gctaagtgca acatgccccc
    51421 agcgaggaat cttgaacgta cgtgcaagaa accaaaaagc caatccggca cagccgacct
    51481 taagcaaagt cagaacatac agtgcatctg gcatcatctg gtttggaaaa aagaacacca
    51541 gtggcgtgaa gatcccgcct agatagtaag aaattaaaga taaataattc aatcctagag
    51601 aagcattcca tgtataaaaa atactttgct ttccaagaag aacatttcgg aagctggcat
    51661 gaaaattaga aaactgtgaa aaggcatcac ttgccaaaat acttctgctg cttccaggat
    51721 agattccgat acttagataa acaagtgcta aaatcaaaaa cggaatcagg aaactagctg
    51781 ctgcgtagcg tccgttttct ctaaagaatg actttaaatt ttttttcata tttattttcc
    51841 accaaatttc tatgaagttg tattcagttt atcatatcct tgtttttctc tgcttaaaaa
    51901 gagtctagtt ttcacaaaaa aataaaattt agaataaata acttcataat ttgttcgtat
    51961 aacaaaaata aacgcaaaaa aagggtagga atcaaaagtc ccacccttaa aaatttttat
    52021 taaataaaaa accgttcact atctgaacgg tccaagtatc attcaattaa acgcgttcaa
    52081 cttttcctga tttcaaagca cgagttgaca cccaaacttt tttaggtttt ccgtcgacca
    52141 taacgcgaac tttttgtaag ttaggtttaa cagtacgttt tgttgagttc atagcgtgtg
    52201 aacggttgtt tccacttttt gtcttgcgac ctgtaaagta acaaactttt gccatggtaa
    52261 tttcctcctt tgccttgatt tggagcaata gaataattca gctcatacca gactaacata
    52321 tcatatagaa tgggaatttg caagtacatt ttcatagata caattgacaa ttgagaagaa
    52381 taattgtaaa ttaaacaagg ttatacctga aattttgcaa ggtttttgag tactttgggt
    52441 aactgccttt tatttcaagt tgcgctatga taaaatatga tagaagaaaa atgggagttt
    52501 tttacccgtt aaggaggctc attcatggct gtaaaaattc aaacgtcagc tggaaccatt
    52561 gaaattacca atgatgtaat tgcaacagtt gttggtggcg ccgcgacaga tgtgttcggt
    52621 gttgtaggaa tggccagcaa aaatcaaatt aaagataata ttactgagat tttgcgtaaa
    52681 gaaaattact caagaggagt agttgtccgc caagaagata atggtattgc tgtagatgtt
    52741 tatacgatta tcagctatgg tacgaaaatc tctgaagttt cccgcaacgt ccaagaaaaa
    52801 gtgaaataca atctagaggc attattaggc gtaactgcca attcagttaa tgtctttgta
    52861 caaggtgttc gtgtactgcc agactaggca ggagactggc tggtaactca gcagtcgatc
    52921 tgaaggagga ttatctaggt gagtgtaaca gaaataagtg caagccagtt ccaggaaatg
    52981 gtccaggcag gtgcgaatcg tctgcaagta aatgcagaat acgtcaattc attaaatgta
    53041 ttccctgtgc cagatggcga tacgggaaca aatatgaatc tatctatgac tagtggagct
    53101 aaggcagtag tagattcaac ctcagaaaaa gtaggagaat tagcagcaat gctttcaaaa
    53161 ggattgctga tgggtgcgcg cggaaattcc ggcgttattt tgtctcaatt gtttcgtgga
    53221 ttttctaagc aaattccaga tgttgtctca ttaaatgctt ctgatcttgc tgcagccttc
    53281 actcatggag ttgaaactgc gtataaagca gtaatgaaac cagtagaagg aacgattttg
    53341 acagtagcta gagaagcagc gaaagctgga gaaaagaaag caaaaagtac tgatgatgtc
    53401 gttgaagtaa tgacagctgt tgtaaaagga gcaaagcgtg ctttagctaa aactccagac
    53461 ttgcttccag tcctaaaaga agtcggtgtc gtagacagtg gagggcaagg actgctgttt
    53521 gtttatgagg gctttttaag tgcattgaat ggagaattcc aagcggatga aacatatgaa
    53581 ccttctccag cagaaatgga tgatatggtc aatgcagaac atcatcgcag tgtccaaggt
    53641 caaatggcga cagaagatat ccattttggt tactgtacag aaatcatggt aaaaatcgga
    53701 gaaggaccta cagtcgatag tacattcgat tacgaagaat tccgtaacta tttagatggt
    53761 ataggagatt ctttacttgt ggtcaatgat gacgagatca tcaaagtcca cgtgcataca
    53821 gaaaacccag gagaagtctt gaattatgga caaaaattcg gttcattagt caaaatcaaa
    53881 gtcgacaaca tgcgcttgca gcatgagacg attttggaac acgatgaaga agtgaacgag
    53941 tttgcgaaaa aagaaatacc acgtatcccg tatggtatcg tagcgatcgc tgctggtaaa
    54001 ggcgtccaag agctgtttga aagtttaggc gctaattatg ttatcagtgg tggacaaaca
    54061 atgaatccaa gtacggaaga cattgttaaa gcgattcaag aagtaaacgc agataaagtg
    54121 attgtcttgc caaacaataa gaacatcttc atggcagctg atcaagcagc agaagtagca
    54181 gatatcccag tagcagttgt tccttcaaga acgatttccc aaggattgac agctatgctt
    54241 tcattcaatg atcaagcttc tttagaagaa aacaaagaaa cgatgacaga aatgttgtct
    54301 agcgttgtga gcggtcaagt cactcacgcg atcagagata cctcaattga cggtgtagag
    54361 atcaaagaag gagacttttt gggcatgatc gatggaaaaa tcctgatctc taacccagat
    54421 atcacagcaa cagcgttaag tacactagaa caaatgatca atgaggacac agagatcgta
    54481 acgatcttgg caggtgatga aggaacagtt gaacaagcaa atgaatttgc tgagaaacta
    54541 acagaaaaac atcctgattt ggaaatcgag atccaccaag gagatcagcc tgtctatcct
    54601 tatctatttt ctgctgaata atttctgtgt cagaatatct ttctaacaca gtattcattc
    54661 ataaaaggcc ttcggttagt gatcaggtat gatcgctgac caagtccttt ttttgttaaa
    54721 ggagggagga aaaatttatg cgttctttag atgatccaat cactatgctg gcaggagtcg
    54781 gagaaaaaag agcagctagt cttgccagct tgggcatcca aacgattgaa gacttactga
    54841 cttattatcc ttttcgctac gaagatattc aggaaagaaa tctaaacgag atccaggatc
    54901 aagaaaaggt tactttgaaa ggaatcgtag tctcgcctcc tgtgatgaat cgatttggtt
    54961 ataaaaaaag ccgattgcaa tttcgtatga tgcaagaaca tgatgtgttc aacgtttctt
    55021 tttttaatca accttatcta aaagaaaaag tcattttatc ggaggaaatc gccgtatacg
    55081 gtaaatggga tgcaaagcgt aaagccttga acgggatgaa gattttaggt tctcaaacaa
    55141 tggatgactt ttcgccgata tatcacgtca acaaatcaat tcgtcaaacg acattagttg
    55201 atctaatcaa aaaagggttt caagaatacg gcacattgat tgaagaaaat ctgccaaaca
    55261 accttgtgga gaaatatcga ctgcttgacc gagcttctgc tgtaagaagt atgcattttc
    55321 caaaagacca cgaagaaaac catcaagcca aacgacgtgt cgtttttgaa gagttctttt
    55381 tatttcaaat gcgtcttcaa ggattgaaaa aagcagaaaa agcagaaacg aatggtttgg
    55441 agatccttta tgatgtccaa aaattgaaac aatttactca aaagctacct tttgaactga
    55501 caaatgcaca aaaacgtgta acgaatgaaa tctgtcggga tcttcgcagt ccgcagcata
    55561 tgcagcgact tttgcaggga gatgtaggta gcggaaaaac agtggttgcc gcgattgcgt
    55621 tatacgctac cgttacagca ggtttccaag gtgcgttgat ggtgcctaca gaaatcttgg
    55681 cacaacaaca tatggaaagc ttgcaacagc tgtttgatcc caatgaagta accatcgcat
    55741 tgattacggg gtcaacgaaa gcaaaagaac gacgtgagct ccttgaaaaa ctagagcaag
    55801 gggaaattaa cgtcgtgatc ggcacacatg cattgatcca agatggagtc gaatttcaga
    55861 atttaggtct agttattacg gatgagcagc accgttttgg cgtgaaccag cggaaagtac
    55921 ttcgtgaaaa aggctggcga ccagatgtct tatttatgac agcgactccg attcctagaa
    55981 cattagctat tacagcatat ggtgagatgg atgtatctat cattgatgaa cttccagctg
    56041 gacgtatccc gatcgaaaca cgctgggtaa gaacacctca attggacagt gtactggatt
    56101 ggacgaaaaa agaactggca agaggacatc aaatgtatgt catctgtccg ctgattgaag
    56161 aatcagaagc attagatgta aaaaatgcag tggaaatcta tgaaaaactt cgtgaactat
    56221 ttgcaccaaa atatgaagtt ggcttgttac atggtaaaat gaagaatcag gaaaaagaag
    56281 taatcatgga agccttcaaa gacaaccaga tgcagatatt agtttcgact actgtaattg
    56341 aagtaggggt aaacgtgccg aacgcgaccg tcatgctgat catggatgcg gatcgatttg
    56401 gattggcaca gctgcaccaa cttcgtggac gtgttggacg cggaagtgat gcttcctact
    56461 gtatcttagt tgctaatcct aaaaatgaac taggtgtgga acggatgaaa atcatgacag
    56521 agaccaccaa tggttttgta ctaagcgaaa aagatctgga attacgtggt cctggtgaag
    56581 tatttggctt ccgtcaatct ggtctgcctc aatttgcgat tgctgacttg gtgacggatg
    56641 gaaatgtttt ggaggtagcc agagaagagg ctgcagccct ttggcaaata aaggattggc
    56701 agatgcttcc tgagtatcag cctttagcgc aaagcctcca aatagaaaat caggataatc
    56761 gttatttcga ttagcagact gtgctatact ttatactgat gacggaaaaa ggagtggaaa
    56821 caatgaaaat tgccgtagat gcaatgggcg gagatcacgc acctcaagca attgtagaag
    56881 gcgtggcttt agcgcagcaa gattttccag aagtagaatt cttactttac ggaaaagaag
    56941 cagaaatcaa gaaatactta acaaatgaaa aaaacatcac gattatccat acagacgaaa
    57001 aaatcaatag tgatgatgag ccagtaaaag caattcgacg aaaaaagact gcatcaatgg
    57061 tccttgctgc acaagcagtg aaaaacggtg aagcagatgc tgtattttca gcagggaata
    57121 caggcgcgct actagcagca gggttgttca tcgtaggacg tatcaaaaat atcgaacgcc
    57181 ctggcttgat gtctaccttg ccagtagtag ggaaagaagg tgccggtttc gatatgctgg
    57241 atcttggcgc taacgcagaa aacaaaccag aacatttgtt gcaatacggt attttaggtt
    57301 ctttttatgc acgtaaagtc cgaggtatcg gacgtcctcg tgtcgcactc ttaaacaacg
    57361 gaacagaagc aacaaaaggt agtgaagtga cgaaaaaagc ctatgaactc cttcagaatg
    57421 aaacaagctt gaattttatt ggaaacgtag aagctcgtga gctactcaat ggtgtggctg
    57481 atgtagtggt cacagatgga tttacaggca acgctgtttt gaaatctatt gaaggaacag
    57541 caatgaatat gatgaatcta ttaaaatctg ctattctaaa tgaagggatc aaaggaaaaa
    57601 tgggcgctat gcttttaaaa gacggcttac gttctttgaa agcagaaatg gattattcca
    57661 aacatggcgg tgccgttttg tttggcttga aagcaccagt cattaaaact catggagcaa
    57721 caggccccga tgctgttcgc tatacgatcc gccaaatcca cacaatgctt gagacagatg
    57781 tagttggaca attagtcgaa caatttgaaa aaagcgaaga atagtatttg gatatctgaa
    57841 gcgatccgtt ccattgaaaa aaaggtggac attcctgaaa aatgccagta aaattagcca
    57901 tggtgtaggt aattgacaag tgtatgattc ttggaggtga aaaagttgac tcgcgaagaa
    57961 gtatttaaca aagtagcgaa aattatttca aatcattttg agatagatac cgataaagtg
    58021 acggatgaat tgaacatcaa agatgattta aaagctgatt caattagtat tatggaattc
    58081 gttttagagc ttgaagatga attcggtacg gaaatttcag atgaagacgc tgaacaaatt
    58141 gaaacagtcg gtggcgcagt agattatatc agcagccatc ttaaataatt tcaaataaaa
    58201 gcaaagaagg ataaaaagct gcatgcagct ttttatcctt ctttttttaa tctttttgac
    58261 acgtaaaagt catttttctg ataattctgg cgataaacag aaattatgtt gcaaagtaaa
    58321 gcggttttct atataattat taataattca ttacacaaag ataagaataa cctttgttat
    58381 aaaacgattt attctgtgta atgtcctttt ttattaagaa aaacttccat ttaggaagca
    58441 gagaggggta ttcgattgtc cgataaccaa ttattagaag ttcagaacct acatacagga
    58501 ttccgactca aagatgacta ttacgatgca gtagatgacg tttcatttac tttagacaaa
    58561 aacgagattt tagcaatcgt tggggaatct gggtgcggga aaagtacctt ggctactacg
    58621 attatgggat tacttgatcc taataacaca aaaattacag gtgagatttt atataacgat
    58681 ctgaatttaa tcgacctgaa cgaaacgctc tataataaaa tccgcggaaa tgatatcgga
    58741 atgattttcc aagatccgtt gtctgcatta aatcctctca tgagaatcga agaccagatc
    58801 aaagaaggac tttcctatca cacaaagatg aatgcagaac agcgtcaagc tcgtgcacta
    58861 gaattgctag aacaagtagg gattcctaat cctgcgagag ttggacgcca atatccccat
    58921 gaactatcag gcggtatgag acaacgtgtc atcatcgcaa tcgcaatcgc ctgcaaacct
    58981 ccaatcgtca ttgcagatga accgacgaca gccctagatg taaccatcca agcacagatt
    59041 cttgatttac tgaaagacct tcaggaagaa acaaaaacag ggatcatctt gatcactcat
    59101 gacttaggag tcgtagcaga aatggctgat cgagtggcag tgatgtatgg cggacagttc
    59161 gttgaagtag caggtgtaaa agaactgttt gatcatccta agcatcctta tacacgctct
    59221 ttactgaact ctataccaca agaaggaaat catgatgcag aactccatgt gatcgaaggt
    59281 gtcgttcctt ctctgaaaaa catgcctcgt aaaggttgtc ggtttgcacc acgtattcca
    59341 tggataccag caagcgatca tgaagaagag cctatccttc atgaagtcgc accgaaccac
    59401 ttggtacgtt gctcctgcta taagcatttc cactttagag acgaaaaagg agaggtgtag
    59461 atgacagaat taatcacaat caaagacctg aaagttcatt accctattcg cagtggattc
    59521 ttcaatcgag taacggatca tgtatatgct gtagatggtg tggattttat tatcgaaaaa
    59581 ggaaagacat atggtttagt gggagagtct ggctctggaa aatctactac gggaaaagcc
    59641 gttgtgggat tagaaaaggt aacagccgga caaatcatgt atgaaggaaa agatgtaacg
    59701 aagcgaagca accgcaaaaa aatgggttat aacaaggatg tgcagatgat cttccaagat
    59761 tcaatgtcca gtttgaatcc taaaaagcga gtgttggata tcattgctga acccatccga
    59821 aattttgaac ggttaagcga tcaagaagaa aagaaaaagg taaaaggact gctagatatc
    59881 gttgggatgc cggaagatgc gctatataaa tatcctcatg aattttcagg cggacaacgt
    59941 caacgtctag gagtagcccg tgctgttgct accaatccaa aactgatcgt agccgatgaa
    60001 cctgtatctg ctctggatct atctgttcaa gcgcaagtat tgaatttcat gaaacgaatc
    60061 cagcaagaat acggcctcag ctatttattc atttcacatg atttaggtgt agtaaaacac
    60121 atgtgcgaca atatcgcaat tatgtacaaa ggtcgatttg tagaaatcgg tacaagagaa
    60181 gacatttata atgacccgcg acatatctat acgaaacgtc tgctttcagc tattccgcaa
    60241 atcgatgtag aaaataggga aagccacaaa gaaaatcgac gaagagtaga acaagagtat
    60301 atccaaaacc aaaaagaata ctatgatgcg actggtcgag tctacgattt gcgtacgatc
    60361 acaactacac acaaagtggc gttgaaagat ggaggtgcaa gctaatgtgg aaaacgattc
    60421 tgcgacgtgt tttattgatg atcccgcaag ttattatttt aagtgttctg atcttcttat
    60481 tagcccaagc gatgccgggg gatccattta ccggtttgat caatccaaat caggatccgg
    60541 cagtgatcga acagatgcga caagcagctg gcttgaatga cccatggtat gtccagtact
    60601 tccgttggat cggaaatgct ttgcaaggcg attttggtca aagtttctta tacaaacgct
    60661 ctgttgctga cttgatcggc gaacggatca tcaacacttt atatctatcg atcttgacag
    60721 ttgtccttac ttatttgatt gctgtgcctc tggggatgct tgctggccgg tatcaaaatt
    60781 caatcttgga taagattgtc gtaatctaca acttctttag ttttgctgtt cctttattta
    60841 tcttcggctt gatcatgcta tttgtttttg gttatcgttt aggctggttc ccaacaagtg
    60901 gatcacaaac actaggtttg caaggtggat ttatcactca atggatagac cgtttgaaat
    60961 atattctgtt accatcaatt acccaagcat ttttggcgac tgccgtcaca atccaatatc
    61021 tgcgaagtga agtaatcgat tcgaaatcgc tcgattttgt cagaacagcc cgttccaaag
    61081 gggtaccgac gaataaagta ttcagtcgac atattttccg aaatgcagcg ttgccgatgg
    61141 cttctcaaat ggggtatgaa atcacttcgt tgattgctgg ttctgtagtt atcgaaaaga
    61201 tttttggtta tccgggagtc ggaaaactat ttattgattc catcggccaa cgggactata
    61261 ccgtgatcac atccttagta ttgattttag gaatcgcgac gctagtgggg acattacttt
    61321 cagatatcat catgagtatc gttgacccgc gtattcggat tcaataaaac caatcagaaa
    61381 ggagaatgga tcgatgagtg aaaaaaacaa tacagcagtt caagaaagta ttcctcctat
    61441 ggggatacga atgattgctc gagaatttaa aaaagataaa attgctattt tttcattagg
    61501 tttgctagtg gttttattat tagtgatctt tatcggtgcg atgctgaccg atcaagacaa
    61561 agtgatgtat gttagtatct tcgacaaata cgctgcacca ggaacagttt cgacacaagg
    61621 acaaaagttc attctgggag cagatgaagg cggacgtgat gtattaggac aattgatcat
    61681 aggtgctaga aactctgtta cgatcggatt tgcgatcacg atccttactt cgatcatcgg
    61741 ggttggatta gggatcatct ctggctacta cggagggatc attgacaaca tcttgatgcg
    61801 gatcgttgat tttatcatga ttctaccgat catgctgatc attatcgtct tcgtatcgat
    61861 tatttccaga tacaatgtct ggtcctttat attcatcatg agtgcatttt attgggtagc
    61921 taaagcccga ttattccgaa gcaagacatt atctgaagca agaagagatt atgtcagtgc
    61981 ctcaaaaaca atgggaacca atgattttaa aatcatgttc cgcgaaatca tgccgaatct
    62041 aagttcatta atcattacta atttgacgat gaactttgcg gcaaacatcg gtatcgagac
    62101 aactttgact ttcttaggtt tcggcttgcc ggcaaatgta cctagtttag gtacattgat
    62161 cggttatgca agtaacggag aagtcttagt gaatcggcaa tggatctggt tacccgcatc
    62221 aatccttatt ttagttttga tgttgagtat caattatgtt ggacaagcat tcaagcgttc
    62281 tgcagatgcg cgccaacggt taggctagta tagaagcgaa gggggaaata ggaatgaaga
    62341 aaacgatttt tggatttgca gcgctgatgt ctgctgtcgt tcttgcagca tgcgggggcg
    62401 gaggtacaga tacctctgga aacaactctg gaggcaacgg caataacaaa gaggaattaa
    62461 cttttccaat tgcaacaaaa aataatgatg atgcaatcga agacggcgaa ttagaagctg
    62521 cggtcgcaac ggacagtcag tttaaaggat tgttccagtg ggagttttac caagattcat
    62581 atgatgcagc ttttatggct ccttctcatg aaccgctatt tgcaaacgat gacgatttca
    62641 gaatcacaga cgacggagct gcaacgcttg atctagatga agatacgaaa aaagcgacaa
    62701 tcaaagtaaa agacaacgtc aaatggtcag atggtgaaga tgtaacggcg gacgatgtga
    62761 ttttccctta cgaaatcatt gggaataaag attacactgg tatccgttat gacgacactt
    62821 tccgtaacat cgtaggtatg gaagaatatc atgatggaag tgccgacaca atctccggaa
    62881 tcaaaaaaat agacgacaaa acagttgaaa tcgaatataa agaagtaaac ccaagcatgc
    62941 ttcaatcggg tggtggtatc tggtcatatg cagcaccaaa acatacgtta gaaggtgtag
    63001 caatcaaaga tatggaatca agcgatcaag tacgtaaaaa tccagtgact tttggccctt
    63061 attacatgag taatatcgtt gcaggagaat cagtagaata cttgccaaac gagcactact
    63121 ggaatggtac gcctaaattg aaaaagatca cgatgaaatc tgtaccgatg gcaagtgcaa
    63181 ctgaagcatt gaactctaaa ttatatgata tgattttcca aatgccaaca gatacttacg
    63241 atacctataa agaaattgct ggctatacaa acttaggccg tgaacaaact tcttatactt
    63301 atctaggatt caagttaggt aaatggaatg cagatacaaa gagtgtggaa tacaatccag
    63361 attcaaaaat ggctgataaa tcattacgtc aagcaatggg ctatgcatta gataataatg
    63421 cagtaggtga acgtttctat gcaggtttga gaagcaatgc gacttcattg attcctccag
    63481 tattccagtc ataccatgat gatgagatga aaggattcac acaagatcta gacaaagcga
    63541 aaaaactatt agatgatgct ggctacaaag atgtggatga cgatggttta agagaagaca
    63601 aagatggaaa taaactaaca atcaactttg cttcgatgtc cggtggggaa acagcgcaac
    63661 cattggcaga ttactatatc caacaatgga aagaaattgg tttggatgtc caatacacaa
    63721 caggtcgtct gatcgaattc aattctttct atgataaatt agaaaacgat gatcctgaaa
    63781 ttgatgttta ccaagctgct tggaatacag gaactgatcc aaatccaagt ggactatggg
    63841 gaccaaatgc tgcgttcaac tacactcgtt atgaatcaga agaaaataca aaattgatca
    63901 acgatatcag ttcaagcaaa gcatttgatg aagagtacca aaaagaagca tatcaaaaat
    63961 ggcaacaata tgcatttgaa gaagcatttg cgattccaac gttgttccgt aatgaagtat
    64021 tgccagtcaa cgaccgtgtc aaagactggg attggtctta tgatgtacca aacccatggg
    64081 caaatgtttc tgttacagca gattcacgtt cataatcact aaaaatgacc gaaaaagggc
    64141 gatgtccttt ttcggttttt tgatattttt ctgtttattt ctctaatatt caggtcaagg
    64201 cgctgatttc atgacttctc caataaacgg tgttcaaagt ccagtttctc ggtattaagt
    64261 caaatttatg caaaaatatg gaaagccatt ttcacaaaat tttttcttca tactcgaaac
    64321 taaacgaatt tttcacaact tctcgtcaat cactaggatt attaaagctt tacttacctt
    64381 ttgaccgaac catttcaaat ttgacaaaaa accagtataa taaggaagta tcgaaaaaat
    64441 atccataaaa ggaatgtgga aaatggacaa ccagctgaca aaagaactaa aagaaaacta
    64501 taacatcgtt tttcacgatc taaatttgct tgaacaagct tttacccatt catcctatgt
    64561 gaatgagcat cgcaatctgc aattatcgga taatgagcga cttgaatttt taggagatgc
    64621 cgttttagaa ctgatggttt ctcagtattt attccgttta tatcctcatt tgccagaagg
    64681 aaaattgaca aaaacacgag ctgcgatcgt tcgcgaagac agcttgtcga aatttgccaa
    64741 agaatgtcac tttgatcaat atgttttgtt gggcaaggga gaagagaatt caggaggacg
    64801 tacgcgacca gcattgcttt gcgacctatt cgaagctttt ttaggcgcgt tatatcttga
    64861 ccagggattc gacacgaccc atgcattcat cgaaaaagtg atttttccta aagtcaaagc
    64921 aggtgctttt tcacatgaga tggatcataa aacaaaacta caagaagtct tgcaaaaatc
    64981 aggtgatgta tcaatcgaat accgattgat caatgaagaa ggtccagctc atgaacgagt
    65041 attttggatc gaagtttatg tagatgatca attgattggc actggacaag ggaaatcgaa
    65101 aaaattagca gaacaagctg cggcggaaaa tgcattggca gcactgtaaa agtaagtgag
    65161 ggaaagcttt gtatttgaaa cgaattgaaa tagccggttt taaatcattt gcagacaaga
    65221 cagtcattga ttttgaaaat agcgtcacag cagtggttgg accaaatggc agcggaaaaa
    65281 gcaatattac agaggctatc cgctgggtat taggagaaca atctgctaaa agtctgcgag
    65341 gcggaaaaat gccggatatc atctttgccg gttccgatac ccgtaagcag ctgaatattg
    65401 cagaagtcac agtgatttta gacaatagtg atcattatct gccattggag tacaatgaga
    65461 tcagtgtaac ccgccgttat cgacggactg gggaaagcga gtttttcatc aataaacaaa
    65521 gctgcagatt aaaagatatc caagaattgt tcttagattc tggattagga aaagaatcgt
    65581 tctcaatcat ttctcaagga aaagtagaag cgattttcag tagtaaaccg gaagaccgtc
    65641 gtgggatctt tgaagaagca gctggtgtct tgaaatacaa gcagcggaaa aagaaagcag
    65701 aacagaagct ttttgaaaca gaagacaacc tcagccgcgt ccaagacatc atccacgaat
    65761 tggaagaaca gttaactcct ttggccgccc agagtgaggc agcaaaggag tttttacggc
    65821 taaaagaaac actgactcaa accgatgtct ctttgatggt tgctgaaatc aagacagcaa
    65881 aaaaagattg ggacaacaaa caagcacagc ttgcgaaatt caatctagaa ttaggcaaac
    65941 tatctgagtc gatccaagaa caagaatcca ttttggcgaa gcagcgtaaa gaaaatgcgc
    66001 aagccgatcg tctgatcgaa aaaaatcagc aagtattatt agatctttcg gaaaaactga
    66061 agcagacaga aggacaaaaa gatgttttgc aggagcggac aaagcataca caaaaaagct
    66121 cgcaagaata tcaaacttca ttagcagaag cacaaaaaaa ggttaaacat tttgaaaagc
    66181 ttcaagaaag cttgatgaaa gcagcagcag aaaaagaaac agagatccaa aaagctgaag
    66241 caaatctcat aaaaacacag caagaattag aaaaatacca aaaatcaacg aaagaattat
    66301 tggcagaatt aagagatcaa tatgttgatt tgatgcaaga acaagcagct gtaggaaacg
    66361 aactgaagta tctagaacgt caatatatac aagaaacagc aaaaagcaag cagacgttag
    66421 ccaagcaatc ggaagtagaa gcatcagtag accgattgat cttacaaaaa gaagaattga
    66481 cacaaaagca ggcgcagcta aaatcatctt taactgaaac aaaagagaag ttagaaatga
    66541 tccaacaaaa cgggaaaaag ttccaagaag cattagcaaa agaacagcct aaaatgtatc
    66601 aattaatgaa tcaagtccag cagctacgtg ctcgtaagaa aagccttcaa gaaatccaag
    66661 aaaactattt tggtttttac caaggggttc gattggtctt gcagcataaa cagcagcttt
    66721 cgggtattgt cggagcagtg gctgaactga tcgatgttcc tgcagatttc acgttagcta
    66781 tcgaagcagc tttaggtggg gcagcccagc atgtcatcgt tgaaaatgaa aaagatgctc
    66841 ggcaagccat cacgtatttg aaacagcaaa gaggaggaag agcaacattc cttccactga
    66901 cgacaatcaa accaagacaa ttaccggctc atatattgac acaagcagca gctgtagaag
    66961 ggtttatagg gattgccagt gaacaagtca gttatcccga tcaaatccaa actgtggttc
    67021 aaaacctgct aggaacgatc cttttagcca aagacttaac tagtgccaat gcaatcgcgc
    67081 aaacgatccg ctatcaatat cgagtggttt ccttagaagg tgatgtgatg aatgccggag
    67141 gatccatgac aggtggagcg aataaacgag gaaaccaagg cagtttgttt gtacaaaatc
    67201 aagaattgaa acagttgact agtgaatttg aagaagcaga taaacaactc caagcacaag
    67261 aaaaaaaagt tcaggagctg caacaagaaa cagctcgttt agccgaagaa caagaagttt
    67321 tgcgtacacg aggcgaacaa ttacgttttg aagaacaaga agcgacaaat cagctacaaa
    67381 acatcataaa tgaacttgaa cgttttgaaa aagaaaagca aatctcaact tttgagacac
    67441 gtgaactgca gcagtttatc gaagattacg aaaagcaaac gaacgaattg aaagacaaac
    67501 aaacagatct tgaatcgcaa cgacaaaaaa tcgacgaaga aatcaaatcg ttaagtcaag
    67561 aaagcgacca gatggaagcc agaagagcac aagtacaaag tcaaaaagca caagaacaag
    67621 cagatcttgc tgtcttgaaa gagcagttta atcatctgca gatccagctc cgcggtgccc
    67681 gagtccaaaa agcagaggca accgaacgtc aagaagcgat agaaaagcag ttggcgacat
    67741 tgacagcaga cttttctgat catgaagtca cagaagaaag tttggaaaaa caaattaacg
    67801 aattatctgc tcagcgagaa acattaaaag ccgagttggc aaaagccaaa gagcagcgag
    67861 atagaaggca aaaggagatc gataagcttg aagcagtctt ggcagagcgt aatcgtgagc
    67921 aaaaagcacg actgtcggaa caatccaaat tagaagtcca aaaagaccga gctgaaatga
    67981 ttttagataa tcatttgacc tatctgcagt cagaatatca gctgacattt gagaaagctt
    68041 cccaagacta tcaagaaaca accgatatcg aagacagtag aacaaaggtt tcatccttaa
    68101 aagaacagat tgaaaaactg ggaccagtaa acttaaattc aatcgaacaa tacgaacaag
    68161 tcagtgaaag acatacattc ttagcaacac agcgagatga tctgttagca gcgaaaaacc
    68221 aattgtttga aacgatggat gagatggatg atgaagtgcg gacaagattc aaagaagtat
    68281 ttgaagctat ccgtcaagaa ttcaaaattg tctttccaaa tatgtttggc ggcggtaaag
    68341 ctgaattagt actgacggaa ccaactgatt tgctgaaaac aggtattgag attgaagtac
    68401 aacctcctgg caaaaaactg caaagtctaa gtttgctttc tggaggagaa cgagcactta
    68461 cagccatcgc gttgctcttt tccattatcc gtgtctgtcc tgttccgttt tgtatcttag
    68521 atgaggtaga agcagcgtta gatgaagcca acgtgaaacg ttttggtcgt tacttgagcg
    68581 atttccaaga tgacacacaa tttatcgtag tcacacaccg caaaggaacg atggtcgcag
    68641 cagatgtact gtacggagtg acgatgcagg aatccggtgt atcaaaaatc gtttctgtac
    68701 ggatggaaga tatcaatgaa gaggcgaaaa tcaacgaaac gaaagtgtag gaacgaaaat
    68761 gatcaaatta gtagcaatcg atttggacgg tacattatta aatgaacaaa agctgatttc
    68821 agatgagaat aaacaagcat tagcacaagc aaaacagcaa ggggtcaaga tcgttctatg
    68881 tacaggacgc cccttagctg cgatggcgca ttatctgcaa gaattaggac tggtagatga
    68941 aggtgactac agcatcactt tcaacggcgg tttggtacaa aaaaatgata ctggtgaaat
    69001 catggaaaag aaagtgatgg aagtatcaga tatccaacgc ttatacaaac tggctcagca
    69061 attggatctg ccactagatg ttttgtctga caatgtggtt ttacagctgc ctagtgcccc
    69121 aaggaagcaa tccttgtaca atgtgttgaa taagctgctg caattccaac cagcggatat
    69181 aagcgatatt acagatgaat ttgtgcttaa taaggcagta atcgcttatg accaagaaga
    69241 attagatcct aaaatcaaag aaataccagc agaattccat gaaatgtatg agatcatcaa
    69301 aacaagaagt atgcttttgg aatttatgcc aaaaggtgtt acaaaagctt atggtatttc
    69361 tttattggca aaagatcttg gtttgaaaca agaagaaatc atggcgatcg gtgatgagga
    69421 aaatgattta ccgatgatcc aatatgctgg actaggcgta gcgatggaga atgctgtgcc
    69481 tttcgtcaaa gaagcagcag atttcgtgac agccagcaat gaagaaaatg gcgtagccaa
    69541 agtgatccaa aaatttgtat tagagtaggg ggagtcaaat gggatttttt gataaaatca
    69601 agcgtgcttt tactggcgaa gagaaaacag aagaagttga agtacaggag aagtacgaca
    69661 agggtttaga aaagacgcgt aaaacatttg gtgaacggat gaatgagttg tttgccaatt
    69721 ttcgaacagt cgatgaagac ttttttgaag aattagaaga aacacttatc ggtgcagatg
    69781 taggttttga aacagcgata cgaatcaccg aagcattacg tcaagaagtg aaactcagaa
    69841 atgcgaaaaa atcggcagaa gtccaaaatg cgatcatcga gaaacttgtg gatctctatg
    69901 aagcggaagg aatcaatgaa gtaaatgaac taaatatcca agaagacgga ctaacagtta
    69961 ttttgtttgt cggtgttaat ggtgtaggga aaacaacaag tattggtaaa cttgcccatc
    70021 agttcaaaaa cgaaggtaaa aaagtattga tggcagcagc agataccttc cgcgctggag
    70081 caatcgacca gttagttgtc tggggcgaac gcgctggtgt tgaagttgtt cgtggcaatg
    70141 caggaggcga tccagcagct gtcgtattcg atgctttgga aagagcaaag acagagcagg
    70201 cagatgtttt actagttgat actgcaggcc gactgcaaaa taaagtgaac ttgatgaacg
    70261 aattagaaaa aataaaacga gtaatccagc gggaattacc agaagcaccc caagaaacac
    70321 ttcttgtatt agatgcaacc actggtcaaa acgcgatggt tcaagcaaaa caattcaaag
    70381 aaacaacaga tgtgaccggt cttgttttga caaaattaga tggtacagca aagggcggta
    70441 tcgtacttgc tatccgtaat gaattgcatt taccagtgaa attggtcggt cttggtgaag
    70501 gaatcgatga cttggagccg tttgatccaa atgattttgt cgttggattg ttcaaaggat
    70561 tactaaaaga agaataaccc atgtctaaaa agcaggagct gtgacaaaag ttgcagctcc
    70621 ttgtttgaat gattgttttt aacatagctg tgtttttgat gccttcattt ttatacttat
    70681 ttgtaagcgg ttctcaaaca atttcgttct ttttcttaga ctttttgatt ataattagat
    70741 tcatatgaat tggaggtcac ttaatgatga attttaagca attattattg catgtcaatg
    70801 cgcgcccttt tatcgaccaa gctcgatttg gtatagaacg ggaaggacag cgggttgatc
    70861 ttgcaggaaa tctagcaaaa accgatcatc cagcaatctt tggcgatcga tcctatcacc
    70921 cctatatcca aacagatttt agcgaaacac aaacagagat gatcacccct gttaccgatt
    70981 ctattcccga attatttcag tatctcgctg ctgtttatga tgtgactgct cgttctatac
    71041 cgaaagaaga gatgatctgg ccattaagta tgccacctgc cttaccggaa aaagacgaag
    71101 agatcattat tgcaaaatta aaaaatttcg aagatgtctt gtatcgacgt tatttagcaa
    71161 aagaatacgg gaagcgaaaa cagatggtaa gcggtattca tttcaatttt gaatttggcg
    71221 atgagttgct aagaacattg ttcagccatc aggaagaatt tcaagatttt tccgaattca
    71281 aaacagaact ttatttgaaa acagcgagaa actttatgcg ctatcgctgg atgatcactt
    71341 atttattcgg tgcttcacca atgagtgaga agaactactt tttagatgaa tcacatccgc
    71401 aagaacctgt tcgcagtatt cgcaacagtg cgctgggcta tacgaatcat ccaaatgtga
    71461 aagtttccta tgcttctatg aaacagtatt tagcagatat cgagcgaatg atcgaagaag
    71521 ggaaactttc ggaggagaaa gaattttata caccgcttcg tttccgaggc ggaaagaaag
    71581 tcgcagattt agcaacaaca ggtgttcgtt atattgaatt gcggaatatc gatttgaatc
    71641 cttatgcaag attgggtatc aatccagagc aagttcggtt cttacaatta ttcctgatgt
    71701 acatgttatg gacagaagaa aaagaagact gtgaccaatg ggtagcagaa ggtacgactc
    71761 gaaataacaa agtagcacta gaacaaccat cagatcaaac agaatttcat caagaaggta
    71821 gagaaattct tgaaggaatg aagcaaatgc tggttgaatt ggattggttg gattctcttt
    71881 atttagtaga ggaagcattg actcaaatgg atcatcctga acaaacgtta gcagcgaaac
    71941 tctatcaaga agcacagcta tcgagtcagc aagaagttgc tgtggcattg ggacatcaat
    72001 attataaaga aagccatgaa cgtccctatc agttggccgg ttttcgcgaa atggaacttt
    72061 ctactcagat atttatgttc gatgccatcc aaaaaggtgt ccaagtcaaa gtattagatg
    72121 agtcggatca atttttgcgt ctgcaattcc aagaccatgt agaatatgtg aaaaatgcaa
    72181 acatgacaag taaggacagc tatatcgtcc cacttatcat ggaaaacaaa acagtaacga
    72241 aaaaagtctt aaaagaagct gggttccggg taccaggagg cgcagaattt tcatccatgg
    72301 aagaagcggt aaaagcttat ccgagatttg ccgagcaggc atttgtgatc aaacctaaat
    72361 caaccaatta cgggttaggt atcacgattt tcaaggaagg agctagtctg gaagattatc
    72421 aagcaggttt agccattgct tttcgtgaag acagttcggt tttagtagaa gaatttatgc
    72481 cgggaacgga atatcgtttc tttgtgatcg acggagaagt ccaagccatc atgttgcgag
    72541 tccctgctaa tgttattggt gacagtatcc gaacagtgaa agaacttgtt gaagaaaaaa
    72601 atagtgaccc tttgcgtgga acgaatcatc gtgcaccttt agaattgatc caattaggtg
    72661 aattagaaca attgatgttg aaagaacaag ggttgacgat cgaatcagtt ccccaagcca
    72721 atcaaattgt ttatctaagg gagaactcaa atatcagtac aggtggtgat tcgatcgata
    72781 tgactgatga attttctgaa gcttacaaaa aaatcgccgt ttctgcggta gaagcactag
    72841 gagctaagat tagtggtatc gatttgatta taccagataa agaaatcgat cctacaactg
    72901 ataaaaaagc atatgggatc atcgaagcaa atttcaatcc agccatgcat atgcatgttt
    72961 atccttttgc aggaaaaggc agaagattga cgatgaatgt attgaaattg ttatatcctg
    73021 aagtatttta aaagaaaaag cttttgacag attgtcc
//
LOCUS       DAZKCW010000006        71116 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000006 DAZKCW010000000
VERSION     DAZKCW010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 71116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.006"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            188..418
                     /locus_tag="ACG84Z_000415"
     CDS             188..418
                     /locus_tag="ACG84Z_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFP9161291.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            515..1816
                     /gene="murA"
                     /locus_tag="ACG84Z_000416"
     CDS             515..1816
                     /gene="murA"
                     /locus_tag="ACG84Z_000416"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFP9161292.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1829..2005
                     /locus_tag="ACG84Z_000417"
     CDS             1829..2005
                     /locus_tag="ACG84Z_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFP9161293.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2140..2436
                     /gene="yidD"
                     /locus_tag="ACG84Z_000418"
     CDS             2140..2436
                     /gene="yidD"
                     /locus_tag="ACG84Z_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFP9161294.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2621..3088
                     /locus_tag="ACG84Z_000419"
     CDS             2621..3088
                     /locus_tag="ACG84Z_000419"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9161295.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3173..4057
                     /locus_tag="ACG84Z_000420"
     CDS             3173..4057
                     /locus_tag="ACG84Z_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFP9161296.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4171..4407
                     /locus_tag="ACG84Z_000421"
     CDS             4171..4407
                     /locus_tag="ACG84Z_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFP9161297.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4495..4575
                     /locus_tag="ACG84Z_000422"
     tRNA            4495..4575
                     /locus_tag="ACG84Z_000422"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4529..4531,aa:Tyr,seq:gta)
     gene            4582..4653
                     /locus_tag="ACG84Z_000423"
     tRNA            4582..4653
                     /locus_tag="ACG84Z_000423"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4614..4616,aa:Gln,seq:ttg)
     gene            4778..4948
                     /locus_tag="ACG84Z_000424"
     CDS             4778..4948
                     /locus_tag="ACG84Z_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161298.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5168..5875
                     /locus_tag="ACG84Z_000425"
     CDS             5168..5875
                     /locus_tag="ACG84Z_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9161299.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5934..6578)
                     /locus_tag="ACG84Z_000426"
     CDS             complement(5934..6578)
                     /locus_tag="ACG84Z_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFP9161300.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6704..6991
                     /locus_tag="ACG84Z_000427"
     CDS             6704..6991
                     /locus_tag="ACG84Z_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161301.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7099..7419
                     /locus_tag="ACG84Z_000428"
     CDS             7099..7419
                     /locus_tag="ACG84Z_000428"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9161302.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7500..8814
                     /locus_tag="ACG84Z_000429"
                     /pseudo
     CDS             7500..8814
                     /locus_tag="ACG84Z_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            8811..9530
                     /locus_tag="ACG84Z_000430"
     CDS             8811..9530
                     /locus_tag="ACG84Z_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFP9161303.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9658..10209
                     /gene="raiA"
                     /locus_tag="ACG84Z_000431"
     CDS             9658..10209
                     /gene="raiA"
                     /locus_tag="ACG84Z_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFP9161304.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10431..12965
                     /gene="secA"
                     /locus_tag="ACG84Z_000432"
     CDS             10431..12965
                     /gene="secA"
                     /locus_tag="ACG84Z_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFP9161305.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13091..14192
                     /gene="prfB"
                     /locus_tag="ACG84Z_000433"
     CDS             join(13091..13162,13164..14192)
                     /gene="prfB"
                     /locus_tag="ACG84Z_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFP9161306.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14297..14983
                     /gene="ftsE"
                     /locus_tag="ACG84Z_000434"
     CDS             14297..14983
                     /gene="ftsE"
                     /locus_tag="ACG84Z_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFP9161307.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14976..15860
                     /gene="ftsX"
                     /locus_tag="ACG84Z_000435"
     CDS             14976..15860
                     /gene="ftsX"
                     /locus_tag="ACG84Z_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFP9161308.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            16012..17460
                     /gene="cls"
                     /locus_tag="ACG84Z_000436"
     CDS             16012..17460
                     /gene="cls"
                     /locus_tag="ACG84Z_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFP9161309.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17797..18654
                     /locus_tag="ACG84Z_000437"
     CDS             17797..18654
                     /locus_tag="ACG84Z_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFP9161310.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18769..19689
                     /gene="pstC"
                     /locus_tag="ACG84Z_000438"
     CDS             18769..19689
                     /gene="pstC"
                     /locus_tag="ACG84Z_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFP9161311.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19689..20573
                     /gene="pstA"
                     /locus_tag="ACG84Z_000439"
     CDS             19689..20573
                     /gene="pstA"
                     /locus_tag="ACG84Z_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFP9161312.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20588..21394
                     /gene="pstB"
                     /locus_tag="ACG84Z_000440"
     CDS             20588..21394
                     /gene="pstB"
                     /locus_tag="ACG84Z_000440"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFP9161313.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21410..22168
                     /gene="pstB"
                     /locus_tag="ACG84Z_000441"
     CDS             21410..22168
                     /gene="pstB"
                     /locus_tag="ACG84Z_000441"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFP9161314.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22181..22858
                     /gene="phoU"
                     /locus_tag="ACG84Z_000442"
     CDS             22181..22858
                     /gene="phoU"
                     /locus_tag="ACG84Z_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFP9161315.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23435..24127
                     /locus_tag="ACG84Z_000443"
     CDS             23435..24127
                     /locus_tag="ACG84Z_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFP9161316.1"
                     /translation="MLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISIL
                     FVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVI
                     GSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPIS
                     VLFFLTVRRLKR"
     gene            24124..24891
                     /locus_tag="ACG84Z_000444"
     CDS             24124..24891
                     /locus_tag="ACG84Z_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFP9161317.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24991..26559
                     /gene="liaX"
                     /locus_tag="ACG84Z_000445"
     CDS             24991..26559
                     /gene="liaX"
                     /locus_tag="ACG84Z_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFP9161318.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26856..27176
                     /locus_tag="ACG84Z_000446"
     CDS             26856..27176
                     /locus_tag="ACG84Z_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFP9161319.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            27176..27526
                     /locus_tag="ACG84Z_000447"
     CDS             27176..27526
                     /locus_tag="ACG84Z_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFP9161320.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27693..28631
                     /gene="hprK"
                     /locus_tag="ACG84Z_000448"
     CDS             27693..28631
                     /gene="hprK"
                     /locus_tag="ACG84Z_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFP9161321.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28646..29476
                     /gene="lgt"
                     /locus_tag="ACG84Z_000449"
     CDS             28646..29476
                     /gene="lgt"
                     /locus_tag="ACG84Z_000449"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFP9161322.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29520..30545
                     /locus_tag="ACG84Z_000450"
     CDS             29520..30545
                     /locus_tag="ACG84Z_000450"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFP9161323.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30560..31498
                     /gene="galU"
                     /locus_tag="ACG84Z_000451"
     CDS             30560..31498
                     /gene="galU"
                     /locus_tag="ACG84Z_000451"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFP9161324.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31623..32063
                     /locus_tag="ACG84Z_000452"
     CDS             31623..32063
                     /locus_tag="ACG84Z_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFP9161325.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            32066..32668
                     /locus_tag="ACG84Z_000453"
     CDS             32066..32668
                     /locus_tag="ACG84Z_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFP9161326.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(32727..33833)
                     /locus_tag="ACG84Z_000454"
     CDS             complement(32727..33833)
                     /locus_tag="ACG84Z_000454"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFP9161327.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            34043..35044
                     /gene="ccpA"
                     /locus_tag="ACG84Z_000455"
     CDS             34043..35044
                     /gene="ccpA"
                     /locus_tag="ACG84Z_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFP9161328.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(35381..37726)
                     /locus_tag="ACG84Z_000456"
     CDS             complement(35381..37726)
                     /locus_tag="ACG84Z_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFP9161329.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     RIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            38005..38907
                     /locus_tag="ACG84Z_000457"
     CDS             38005..38907
                     /locus_tag="ACG84Z_000457"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFP9161330.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            39120..40895
                     /locus_tag="ACG84Z_000458"
     CDS             39120..40895
                     /locus_tag="ACG84Z_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFP9161331.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(40961..42547)
                     /locus_tag="ACG84Z_000459"
     CDS             complement(40961..42547)
                     /locus_tag="ACG84Z_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFP9161332.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            42798..43022
                     /locus_tag="ACG84Z_000460"
     CDS             42798..43022
                     /locus_tag="ACG84Z_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFP9161333.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            43164..44915
                     /locus_tag="ACG84Z_000461"
     CDS             43164..44915
                     /locus_tag="ACG84Z_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFP9161334.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            44915..46699
                     /locus_tag="ACG84Z_000462"
     CDS             44915..46699
                     /locus_tag="ACG84Z_000462"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161335.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            47025..47876
                     /gene="licT"
                     /locus_tag="ACG84Z_000463"
     CDS             47025..47876
                     /gene="licT"
                     /locus_tag="ACG84Z_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFP9161336.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            47969..49855
                     /locus_tag="ACG84Z_000464"
                     /pseudo
     CDS             47969..49855
                     /locus_tag="ACG84Z_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
     gene            complement(49895..50797)
                     /locus_tag="ACG84Z_000465"
     CDS             complement(49895..50797)
                     /locus_tag="ACG84Z_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFP9161337.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            51028..52431
                     /locus_tag="ACG84Z_000466"
     CDS             51028..52431
                     /locus_tag="ACG84Z_000466"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFP9161338.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            52431..53864
                     /locus_tag="ACG84Z_000467"
     CDS             52431..53864
                     /locus_tag="ACG84Z_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFP9161339.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            54009..54935
                     /gene="trxB"
                     /locus_tag="ACG84Z_000468"
     CDS             54009..54935
                     /gene="trxB"
                     /locus_tag="ACG84Z_000468"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFP9161340.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            55149..56876
                     /locus_tag="ACG84Z_000469"
     CDS             55149..56876
                     /locus_tag="ACG84Z_000469"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFP9161341.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            56891..57241
                     /locus_tag="ACG84Z_000470"
     CDS             56891..57241
                     /locus_tag="ACG84Z_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFP9161342.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(57333..58193)
                     /locus_tag="ACG84Z_000471"
     CDS             complement(57333..58193)
                     /locus_tag="ACG84Z_000471"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFP9161343.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            58285..58713
                     /locus_tag="ACG84Z_000472"
     CDS             58285..58713
                     /locus_tag="ACG84Z_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFP9161344.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            58876..59052
                     /gene="rpsU"
                     /locus_tag="ACG84Z_000473"
     CDS             58876..59052
                     /gene="rpsU"
                     /locus_tag="ACG84Z_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFP9161345.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            59079..59525
                     /locus_tag="ACG84Z_000474"
     CDS             59079..59525
                     /locus_tag="ACG84Z_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFP9161346.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(59679..61058)
                     /gene="brnQ"
                     /locus_tag="ACG84Z_000475"
     CDS             complement(59679..61058)
                     /gene="brnQ"
                     /locus_tag="ACG84Z_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFP9161347.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            61764..62735
                     /locus_tag="ACG84Z_000476"
     CDS             61764..62735
                     /locus_tag="ACG84Z_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFP9161348.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            62759..64951
                     /locus_tag="ACG84Z_000477"
     CDS             62759..64951
                     /locus_tag="ACG84Z_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFP9161349.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            64968..65444
                     /gene="ybeY"
                     /locus_tag="ACG84Z_000478"
     CDS             64968..65444
                     /gene="ybeY"
                     /locus_tag="ACG84Z_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFP9161350.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            65428..65823
                     /locus_tag="ACG84Z_000479"
     CDS             65428..65823
                     /locus_tag="ACG84Z_000479"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFP9161351.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            65838..66737
                     /gene="era"
                     /locus_tag="ACG84Z_000480"
     CDS             65838..66737
                     /gene="era"
                     /locus_tag="ACG84Z_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFP9161352.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFTQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            66880..67692
                     /gene="recO"
                     /locus_tag="ACG84Z_000481"
     CDS             66880..67692
                     /gene="recO"
                     /locus_tag="ACG84Z_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFP9161353.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            68076..68993
                     /gene="glyQ"
                     /locus_tag="ACG84Z_000482"
     CDS             68076..68993
                     /gene="glyQ"
                     /locus_tag="ACG84Z_000482"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFP9161354.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            68995..71070
                     /gene="glyS"
                     /locus_tag="ACG84Z_000483"
     CDS             68995..71070
                     /gene="glyS"
                     /locus_tag="ACG84Z_000483"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFP9161355.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGKASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        23298 a        12452 c        15197 g        20169 t
ORIGIN      
        1 tttggaataa gggactgcga caagactttt gtctcagtcc ctttttttgc atatttttag
       61 catttatttc ctaaaaaatg taaggggatt cctatatttt taagtatact tgtttttcct
      121 tttatacatt ttatggtatt atcattttat tagttattat aaaacaatcg ttagaaagga
      181 cgtcattatg caagtatacg gaattgatgc ggtgcttcga atcgtgagtc atttggcgtt
      241 tatctactta gccttctggt ctttacgttc gttacgcatt gaaacttttt tcagaccaat
      301 gcataatacg caaattagaa tggcaatcgt acttttttca atttttttag ggtacactgc
      361 aagtaatttt ttcttagaag ttatcgcttt atgccgaaat cttttcgtta gcctgtaaat
      421 tttaaaaaaa ggtactattt taaaagcaag gatgttataa tagaaaagat tttgagtaag
      481 tgtatgctca ttggaatttt ttggagggaa caacatggaa gagatcatcg taagaggtgg
      541 caatcaatta aatggaacag taagaattga aggagctaaa aatgctgttt tgcctatttt
      601 agctgctagt ttgttagcag aagaaggtat tacgacatta gacaacgttc cgattctttc
      661 tgatgtcttc actatgaatc aagtgattcg tcacttaaac gtagatgtag attttgatga
      721 acaaaagaat caagtaacaa tcgacgcttc aagacaatta gaaatcgaag cgccttatga
      781 gtatgttagt caaatgcgtg cttcaatcgt tgtgatgggt ccgctacttg ccagaaatgg
      841 acatgcaaaa gtagctatgc ctggtggatg tgcgattggt aaacgaccaa tcgatttgca
      901 tttaaaagga tttcaagctt taggagcaaa aattattcaa aaaaacggct atatcgaagc
      961 aattgcggat gaattgatcg gtaacacgat ttatttagat ttccctagtg taggtgctac
     1021 tcaaaatatc atgatggctg ccgtaaaagc aaaaggaaca accatcattg aaaacgtagc
     1081 tcgcgaacca gaaatcgttg atttagcaaa cattttgaat aaaatgggcg ctcaagtcta
     1141 tggagctggt actgaaacaa tgcgtattga aggcgtggat catttacatg cagtcaacca
     1201 ctcaatcgta caagatcgta tcgaagcagg tacctttatg gttgctgctg caatgacaca
     1261 aggcaatgtg ctgattgcag atgctatctc tgaacataac cgcccattga tttctaaatt
     1321 gatcgaaatg ggtgcagaaa tcattgaaga agaaggcgga gtccgtgtca tcggaccaaa
     1381 acatatctta cctacagatg taaaaacgat gcctcatcct ggtttcccta cagatatgca
     1441 agctcaaatg acagctatcc aattagttgc agaaggtaca agtgtagtga ctgaaacagt
     1501 gtttgaaaat cgtttccaac atttagaaga gatgcgccgt atgaacgctc atgtcaaaat
     1561 cgacggaaat gtagcaatca tggatggaaa ccatgaattg caaggtgcag aagtatatgc
     1621 aacagacttg cgggcagcag cagcattagt tttagctggc ttgaaagcaa atggaatcac
     1681 acgtgtgcgt aacttgaatt atctagaccg tggatattat aatttccata tcaaactaca
     1741 gcaattaggt gcagacgttg aacgtgtaga catggatcaa acttctgctg aaaaaacagc
     1801 acaaacgatt gcttaaggaa gtggctgaat gagtaaccaa cgatatatct tattaacttt
     1861 gataaagatt ttaatggtga tcttattgct tatccttctt tttgtggccg gaacgatgat
     1921 cggatatggt gtcatcggtg gcggcaatcc atttaaagta tttcagccaa gtttgtggat
     1981 tcatattcga gacttttttc attgataaat aagaatcaca gtggttctag tcgatatgaa
     2041 gtgagccatg aagcagaaca tgataaaaga aaacagaagg gaacgttgac gttagtcgcg
     2101 atcccttttt ttagtaaaag aaaagaagga atctaattga tgaagaagat attgatttat
     2161 ttagttagag gatatcagcg ctttatttcg cctgcatttc cacctagctg ccgttattac
     2221 ccaacctgtt ccaattatat gataaaagca attcaaaccc atggcgcgct aaaagggacg
     2281 gtaatgggga ctgcacggat cttacgctgt catccttttg tcaaaggcgg tatcgattat
     2341 gtaccattga cattccgatt aacgcgaaat aagaaagata aaaaagaacc agattataaa
     2401 aaggttgtga aaaatacggg tagcactgag cgataaagaa acaatttgga aaatagcttc
     2461 ttatattttg caaaattgtg agttattgcc gaagtgttgg attttgaaca ccgtcaaaaa
     2521 aaaggttgtg aaaaatacgg ctagcactga gcgataaaga aaaagaggaa atttattgtc
     2581 aaagtaacaa ctccgcaact acttatatgg gggacaaaaa atgatcgaag aactaaacaa
     2641 gaaagattta ccatggtcct tgttattaga tgcagatcct gataaagaaa aagttcaagt
     2701 atatgtttcc agagggagtg gctggatatg gaaagaaaaa gaaaaaacaa taggtgtact
     2761 gatctatgtg gcaagggaaa aagaatacga aatcgtcaat gtagcagtaa ccccaacgta
     2821 tcaaggaaag gggattggcg gaaaattact tgagacagct tttcagaagc tttcacaact
     2881 cgcttccagt caaactcaga tcatcatacg aaccggcagt actagcagtg cggcgttaca
     2941 tctctatcaa aaaatgggct atgtggagat tggtcgagtc aaagactatt ttatccatca
     3001 ttactctgag cccatttttg aaaatggaga tcaattaagg gatcaagtga ttttagcaat
     3061 tcacttacct aaaaatagct ttaactaata aaatttcaat tcaagaaaat gctttcaaat
     3121 gctaaataga tacattacaa tagctttagc aaacaaaaag gagaatattt ttatgggaat
     3181 attagttttt gattttggtg gatcggctgt caaatatggt tgttgggatg gcaaagagat
     3241 taaaggtaag ggacaatttg caacgcctga atcttgggaa gaaatgaaag cgcaattatt
     3301 tcaagtttat aaaaaaatac tcgtttcttt tgaagtcgaa ggaattggaa tcagctctcc
     3361 tggagtagtg aataatgaga aacaggtgat tgagggaatc agtgcgattc cttatattca
     3421 tggatttaat attttccgag atttggaaac tctgtttcaa cttccagtaa cgattgaaaa
     3481 tgacgccaac tgtgccggaa tggctgaatt ttatgaaggt gctgcccgcg attatcaaga
     3541 tgttgctttt gttgtggcag gaactgggat tggcggggcg ttgttcacga aaggacaaat
     3601 caataaaggg gcacatcttt acggtggaga atttgggttg atgttcttaa atggcgataa
     3661 gacattcagt aaacttggta cagcggtaca gatggcttgg cgttattgtg aacgcaaagg
     3721 tctcgataaa aatgcttata ccggaaaaga tgtctttgaa ttagcagaaa ctggagatgc
     3781 aatagcaaaa gaagaagttg agagttttta tacgtatctt acaaagggat tattcagtat
     3841 tcaattttcg tttgatccag aagtgatcgt attaggcggc ggggtttctg caaaagaagg
     3901 gctcattgat gagatcaaaa gccgaatgaa gaagctgaca gaacaattcg atctgcatga
     3961 tttcgaaccg cagattttat tatgtgaata cagaaacgat gctaatcttg taggtgcagc
     4021 agcaaactat ctcgctgtac gtcaagggga gaattaagag ctttagagaa ggtgcagctt
     4081 gcataaaaga agtgaatgaa atgaatagga gatttttacc taaggaatgt tttatttgct
     4141 gcagtatgat aaaatatctg agaggtgaaa atgatgtcaa aaaaaaataa agatattgaa
     4201 gtgcgtatag aagaagtgaa aaaagatatc aaaggtaaga attatgaagt cactcagtta
     4261 tttataggga aaaaaatgat tggtgagatc ttagcctatg gaccaaaaga atatgaaatt
     4321 ttctttggtg aagaagattt tggaaaagaa aaaagtcttg aaaatgcgat agaaacagtg
     4381 attcgacact ggaatctgca cgaataaaaa aatatcaaaa aaactttcaa taaagggttg
     4441 caaaaatctg gaaaattagg tattataact aagtcaggtt gatacaaacc tttcggagga
     4501 gtagcgaagt ggctaaacgc gacggactgt aaatccgttc cttagggttc agtggttcga
     4561 atccactctc ctccatttca ttggggtata gccaagcggt aaggcaaggg actttgactc
     4621 cctcatgcgt tggttcgaat ccagctaccc cagtatacca caatcgtaag ctctcgttag
     4681 ttcgagagct cttttttttg ctttgctacc ttgttccttg aagattctgc tgatttaaga
     4741 tagagttaag ttaactacaa gaattggagg gatccacatg aaatggaaag aaaaagtaga
     4801 cgaagcagct gaaaagttat atgatttggt caaatcagaa aaatacaata ttgaagtgaa
     4861 tattccgaaa aaaggcggaa aagcggtccg ggtaaaatca aaacgcccaa cgaatcatac
     4921 aaaaaaatgg atggctaaaa accgctaata ataacaaaag atccataagt cggcattttc
     4981 atcgatttta gggtcttttg ttattttcta ggttggacat atctaaaaaa ttgtttctga
     5041 caataggagt aggaagaacg atgtgtgtct aaatcctctg ttgatggata gaaaccttta
     5101 tctttttcag ttgtgaatca ggtatatacc agttataata gaagaaacga aaggacgggt
     5161 gtacgttatg tcgaatcaat tacctgtata tatacagatt catgaccaat taaaaaatga
     5221 aatcgaacaa ggtatatgga aagtcggaga ccgtcttcct tcagaaagag aattagcagt
     5281 gaaattcaat gtcagccgta tgacgttgag acaagcaatt caaaacttgg cagatgaagg
     5341 aatcttagaa agaaagatcg gttcgggtac atatgttgca cgagaaaaag tacaagaaaa
     5401 aatgtctggt gcaacaagtt ttacagaaat tatggaatca caaaatcgag taccgtctag
     5461 tcggacaatc tcttatttct tgacttcgcc aagctcaagt gaaatggaaa aactaaactt
     5521 gagtaaagat gacacgatct tgcgaatgga acgtattcgt ttcgcagatg atgtccctat
     5581 ttgttttgaa gttgccagtg tgccacaaaa gctgatcgat ggctacagca aagcagagat
     5641 tactgaatcg ttgtatcgca cgctagaaga aaaaggcggg aaaaagatcg gtccagcgaa
     5701 tcaaacgatt actgctgtgt tggcttctga gaaaattgct gactatttag aggtaaaacg
     5761 aggagatgca gttcttcgtt tgcgccagat ttcttatttt gaagacggta cgccgtttga
     5821 gtatgtgcgt acgcaatacg taggaaatcg ttttgagttt tatttggaaa aataaaaaac
     5881 aggtgatccc tgattccgta ttagaaataa aagagaatca gaatcacctg tttttatata
     5941 tgatcagtta ccagttgctc gtgataagaa acaggaccct cttcaaattg gacttgtccg
     6001 ttcagcagct caatgatgga ttctttaaag tggtcagcac ttttttcatc tacagcacag
     6061 atgacgctaa cttgatcagt atattggatt tcttttataa aaaaatgttg gagttcaaga
     6121 taattctgta attttcctag ttgcggatac gtgatcatca cagagatctc ctgttgcaag
     6181 gtaccttcta cgattccaat gtcagacaat gcttgagaga ccgcatgagt gtatgctcgt
     6241 attaatccgc ctgtgccgag tttcgttcct ccaaaatatc gagtgactac tgcagctaca
     6301 ttgatcagtt gatttttttt gaggacttcc aacatcggta tgcccgccgt tccacttggt
     6361 tctccatcat cgctgcttcg ctggatttca tttttttctc caatgatgaa ggcgctgcag
     6421 ttatggttcg ctttccaatg ttcttttttt atttcttgaa tgaaactttt tgcttcgtcc
     6481 tctgattcta ttcgtctaag agaacagata aagcgtgatt ttttgatctc gatctcactt
     6541 tgtccatttt cttttattgt acgatagcgc tcgatcatct tgtcacctct tttttcattt
     6601 tctttattca gtataaataa agttctaggt tgtttcaaca ctgtaacggt tgcgcaattg
     6661 ctgtagtatg cgataataaa gacaaaggca ggtggatctg gggatgcagg aacgaatgaa
     6721 aaagtacgat gcaattacgc attatttgaa gaacaatggc ggctctcaag taacgttgac
     6781 ctttacccaa tttgacgaac tgctgtttcc cagtaacgga cttcccaaaa cagcaaggga
     6841 aagtacagat tggtgggcaa atgattataa acaccctgaa aaaggtgcct atggctggat
     6901 aaatgcaggc tatgaagtag ttgtcatcaa tttggacaaa gaatatgtcg tgttcaataa
     6961 attagtgaaa tctagttggc tatttgatta aataaaccgc gtttagaaaa cgttgacaaa
     7021 tttctttctt tttatataat agagtaacag acgcgaagaa aacgtttgcg tagtttgttt
     7081 taaaaaggag agaaaagtat ggctaaaaaa acaatcatgc ttgtatgttc ggctggtatg
     7141 agcacaagtt tactagtaac aaaaatgcaa aaagctgctg aagcaaaagg aatcgactct
     7201 gatattttcg ctgtgtccgc ttctgacgca gataacaatc ttgcaaataa agacgtggat
     7261 gtgttgttat taggcccaca agttcgcttt atgaaagctg attttgagaa acgtctggaa
     7321 ccaaaaggca ttcctttaga tgtcatcaat atggctgatt atggtatgat gaatggcgaa
     7381 aaagtgttag atcaagcaat cacgctcata ggtgaataaa tagaacagta taactatcga
     7441 acaagcgatc caaaaaatag atcgcttgtt ttttcgtata tttttttagg gcgaataata
     7501 tgaatcattt ttggggtaga aggcttctga cgagagatat taaagcaata gactgtgagg
     7561 aggtaaattt accaaattat gagaagatcg cagcagtgga acgtttgagc aactggattc
     7621 tttgtcatcg ctgtggaatg agaacgtccg tcattgatgg acagcttgca gattacggtt
     7681 atttttgtac acattgtcta tatttagggc gatgcgacac tcaacaagat ttatatttgt
     7741 ttgatcagcc tgaagcaaaa cctcgagaag tcgtcttttt tttggacagg acagcttact
     7801 gaaaaacaaa cggaaatctc aaagagaata ctttgccatt cagaaaaaag acatcatctt
     7861 atttgggctg taacaggtgc agggaaaaca gagatgcttt atcctatttt agtggaaact
     7921 ttaaaagctg gaggaagagt agcgatttgt acaccgcgag tcgatgtttg taatgaattg
     7981 tttttacgct atcgttatgt ttttccagaa gaaaaaatca cgttgctcca tgggaataca
     8041 gcaacggctt atacctttac ttcttttgtt atctgtacga ttcatcagct ataccgtttt
     8101 tatcggtcct ttgatttaat agtgatcgat gagatcgatg cgtttcctta taacggggat
     8161 gcaggattag ctcatgctgt gcaaacagcg attaaaccag acggacgatt catctactta
     8221 agtgccacac ctgataaaaa gttactaaag gagatcaagc agacgtttga catccacaaa
     8281 cttgctttac gctttcatcg gcgtttgctt cctgaacccg tcttggtttt catgaataat
     8341 tggcgacaaa aatgcaagaa caagaagaag ataaaatctt tggtgcggat cattcatcaa
     8401 ttaattaaag aaaaccatat ccttttattt tgtccaagta tcacgatgat gcatcgtttg
     8461 aaagccacac ttcaagaggc tcttccgaga tatgagatca cagatgtttc ttcaagagac
     8521 aatcagcggg cggaaaaagt ccagaaaatg cgagaagcaa aatatgacat actgttaacc
     8581 acgatgatcc ttgaacgtgg agtcacattt gaaagaatat ccgttatcgt tttaggagcg
     8641 gatcatccgg tttttactaa atcttctttg gtacaaatcg caggaagagc cgatcgtaaa
     8701 gggccttata cgaacagtca agtatatttt ttctatgaag aaaaaactgc agctattcga
     8761 aaagcttgtc aggaaatcaa agaaatgaat gaagaaggga agaagatact gtgaggtgca
     8821 gttgctgcag taaagatatc gtccaaaatt taacattcag cgagattatt ggtgtttcga
     8881 aatacagatt acctcagact tgttcagttt gtcgcgcaca atttcattta ttggaaacaa
     8941 gaggctgttc tggctgtcaa aaaccaatcc atttcaatct agagagtacg aaaaagaaag
     9001 taaattctat ccccgtttac tgcagtgact gtcaagaatg gaagaagaaa tatccgacct
     9061 atgattttca gcaccgtgcc ttttttgtgt acgatgaaaa tatgaaggcc tggctcaatc
     9121 aatacaagtt tatgggagat atccgactag caggcacctt tgcatataaa tggacgcaga
     9181 taaaaaaaga atacccgaca tacatctatt gtccaatacc tttatctgaa aaaaggcgaa
     9241 cagaaagagg attcaatcaa gtaagcgaga tgttgaaagc agcaagaatt ccttttcaga
     9301 tgctactcaa aagagagaag catctgctgg ctcaagcaaa aaacacgcga aaggaaagat
     9361 tggagatgcc tcaacctttt gaacttgcag tcaccttttc taagatacaa aataaaaaaa
     9421 tattgattat tgatgatgtc tatacaacag gacagactct tttccacgca gcagattgtt
     9481 tgcagatcgc acagccgaaa atcatccgaa ctatttcttt ggcgagatga attagatgtg
     9541 gaaatttgat agcgatttaa tttgcaaata acctagagtt cgatataata gaattaagaa
     9601 gagggaaaga gtggtccttc tccttcttga ttgtggtaga cgaaaggggt aatttttatg
     9661 tttagatata atgtacgcgg cgaaaatatc gaagtaactg aagcgattcg cgactacgtt
     9721 gagaaaaaag taggcaaact agaacgctat ttcagtgacg cacccgatgc aacggcgcat
     9781 gtgaacttaa aagtttatac agaaaaaaca gcaaaagtgg aagtaacgat cccattacct
     9841 tatcttgtat tacgtgccga agaaacttct ccagatttat acgcaagtat cgatttggtt
     9901 gttgacaaat tggaacgcca aatccgcaaa ttcaaaacaa aaattaatcg taaatcccgt
     9961 gaaacgggca tgaatactgc aaatgctgct gctttattca atgaagagga cgaaaacgaa
    10021 aatgattctg aattagatat cgtacgtacg aaacgccttt cattgaaacc aatggatagt
    10081 gaagaagcag tcttgcaaat gaacatgctg ggacataact tctttatttt tgaagatgca
    10141 gaaacaaatg gtacaagtat cgtttaccgc cgtaaagatg gaaaatacgg actgattgaa
    10201 acagactgat cagccttact taaataacaa cgaaaacttg cagcagctac tgacagctgc
    10261 cgcaagtttt tttgagtttc ctcctctttt agatgaaata tgaataaatt atgaagttct
    10321 tactttaata cgcttaagat atttcaatta tctataacta atgataaaat gaaaagtaaa
    10381 gtctacatag tctggataat acacagaagg aaaaggagat tacacaacgc atggccaatt
    10441 tgattcgttc acttatcgaa aacgataaga aagaactaaa acgtttagat agcattgcaa
    10501 aaaaagttga agcatacgct gaccaaatgg cagcattaac tgatgaacaa ttacaggcaa
    10561 aaactgctga attcaagggc agataccaaa aaggagaaac attagatcaa ttacttccgg
    10621 aagcttttgc agtcgtccga gaagcagcaa aacgtgtatt aggtttatat ccataccacg
    10681 tacaattgat gggtggaatc gtgcttcacg atggaaatat ccctgaaatg cgtactggtg
    10741 aaggtaaaac cttgaccgca acgatgccag tatatctaaa tgctctgact ggcgaagggg
    10801 tacacgtagt taccgtcaat gaatatttag caacccgtga ctcgacggaa atgggcgaac
    10861 tttataattt cttaggatta acagtggggt tgaatatcaa ctcaaaatct tcggatgaaa
    10921 aacgcgaggc ttataattgt gatatcactt atagtacgaa taatgaatta ggatttgact
    10981 acttgagaga caatatggtc gtttaccgcc atcaaatggt acaacgtccg ctgaattatg
    11041 ccattgtcga tgaagttgac tcaatcttga ttgatgaagc gagaacgccg ctgatcattt
    11101 cagggcaagc agaaaaatcc acagctttat atacaagagc agacaacttc gtgaaacgtt
    11161 tgaaagaaga agaagattat aaaatcgatg tacaatcaaa aacaatcagt ttaaccgaag
    11221 cagggatcga aaaagcagaa gaaacattcg gtttggataa cttatacgac attgaaaata
    11281 ctgcattgac ccatcacttg gatcaagcat tgagagccaa ctatatcatg cttttagata
    11341 tcgattatgt tgtccaagac ggaaaagtac tgattgttga ccagttcact ggtcggatca
    11401 tggatggacg ccgttattca gatggacttc accaagcaat cgaagctaaa gaaggcgtag
    11461 agatcgaaga cgaaacgaaa accatggcga cgatcacttt ccagaactat ttccgtatgt
    11521 acaagaaact tgcgggaatg actggtacag ctaaaacaga agaagaagaa ttcagagaaa
    11581 tttataacat ccaagtatac cagattccga caaatcgtcc ggttatccgt gatgatcgtc
    11641 cagatttgct ttacccaaca ttacaaagca agttccacgc tgtcgtgcaa gatatcaaag
    11701 atcgctaccg caaaggtcaa cctgtgttag tcggaactgt tgcggttgaa acatctgagt
    11761 tattatcaga tatgctgaat caagaacgta ttcctcatga agtgctgaat gcgaaaaatc
    11821 actttaaaga agcagagatc atcatgaatg ctggtcaaaa aggtgctgtg acgattgcta
    11881 ccaacatggc tggtcgggga acagatatca agttaggact tggggtaaga gaacttggtg
    11941 gtctagcagt tatcgggaca gaacgacatg aatctcgtcg tatcgataac cagcttcgag
    12001 gacgtgcagg acgtcaagga gaccctggta tgtcacagtt ctacttgtca ttggaagatg
    12061 atttgatgaa acgattcggt tcagaacgaa tcaaatcttt cttagatcgg atgaagatcg
    12121 gtgaggaaga tgctgttatc caaagcaaga tgctgacgaa acaagtagaa tctgcacaaa
    12181 aacgtgtaga aggaaataac tatgacacac gtaaaaacgt cttacaatac gatgatgtga
    12241 tgcgtgaaca acgtgaagta atctataaac agcgacaaga agtaatcatg gaagaaaaaa
    12301 gcttatccaa gccactaatg aacatggtca aacggacaat cagtcgtgta gtagatgcgc
    12361 atacacaatt agagaaagaa aattggaatt tggaaagtat catcgatttt gccggcagta
    12421 ctcttgtcca tgaagatagt attactcttg cagatatcga aggaaaaaca gctcaggaga
    12481 tcaaagagta tctaaacgaa cgagcacaag aagtatttaa taccaaagcg gctcaactaa
    12541 atggtccaga gcaactgttg gaatttgaaa aagtcgtgat cttgcgtgtt gtggactcta
    12601 aatggacaga ccatattgat gcaatggatc aattacgtca gtcaatcggc ttacgtgctt
    12661 atggacagaa caatccatta gtcgaatatc aaacagaagg ctataagatg tttgaagata
    12721 tggtaggcgc catcgagtat gaagtcactc gaatctttat gaaagctgag atccgtcaaa
    12781 acgtacagcg tgaacaggtt tctcaaggaa cagcttctca ctcagaagac ggagatgcca
    12841 aagaaaatag taatactagc gcgaaaaaac agccaatcca tgtgaacaag gtcggaagaa
    12901 atgatccttg tccttgtgga agcgggaaaa aatataagaa ctgtcatgga aaaaatgcaa
    12961 actaatttct gacagcagga ttggtgagac aaattctttt tttaagaatt cgtctcacct
    13021 tctttctgtt atttgctgat tctgttagac tagatataat gaaaaaagta tagtgaaaga
    13081 aggaaaaaac atggaaatat ccgaaattcg aaatctcctg acagaaatgc aggaaaaggt
    13141 cacaagcttc aggaggtctc tttgacttag accagctgga agaagacatt gcggaagcag
    13201 aagcaaaaat ggctgaacct ggtttttggg atgatagcga agctgctcaa aaagtgatca
    13261 gtgaaaacaa tgcaaataaa gaaacttatg atcaattcca ttctcttgct gaagaactgg
    13321 aagaaatcga attgatggtg gagatgttgc aggaagaacc tgatgcagcc atgcaagaag
    13381 aagcagaaac acgtatcaat gcgctagatg aaaaaatgaa gacatatgaa ttatctatgt
    13441 tgttagatgg tccttatgat cgaaacaacg ccatcgttga attgcatcca ggggctggcg
    13501 gaacggagtc ccaagattgg ggcagtatgc ttttacgtat gtatacacgc tgggcagagc
    13561 agcatgggta tcaagtagag acactagatt atcaagcagg tgatgaagca ggaatcaaga
    13621 gtgtgaccct actgatcaaa ggacacaacg catttggtta tctgaaatca gaaaaaggtg
    13681 ttcatcgcct tgtacgtatc tcgccttttg actcagcgaa acgacgtcat acttcttttt
    13741 gttcggtaga tgtgatgcca gagcttgatg aaacgatcga tatagaaatc aatccagatg
    13801 atttgaaaat cgatacgtac cgagcaagtg gtgcaggtgg tcagcacatc aataaaacag
    13861 aatctgctgt acggatcact cacttgccta caggaacagt agtagctagt caggcacaac
    13921 gttcacaatt gaaaaaccgt gagcaagcga tggggatgtt aaaagctaag ctttatcaat
    13981 tagaagtgga aaagaaagaa caagaagcag ctgcacttcg aggagaacaa aaagaaatcg
    14041 gctggggttc acagatccgt tcttatgttt tccatccata ttctatggta aaagaccatc
    14101 ggacaaacgt agagacagga aatgtccaag cagttatgga cggtgacctt gatttattta
    14161 ttgacggcta tttaaaaatg catctacaat aagaacccat tgttaaattg aaataaaatt
    14221 gtaagatttt gcaagcatgt tgaaacattg ccatgctata atagctaaag actgaaaaag
    14281 atatggagag aacgccatga ttgaaatgaa ggatgtaatg aagaagtact caaatggtac
    14341 gaccgctatc cgcaatctct caattgtcat cgaacaagga gagtttgtct atgtggttgg
    14401 tccgtctgga gccggtaaat ctacattcat caaattgatg tatcgagaag aaaaagcttc
    14461 aaaaggaact ttgaacgtcg caggtcatga tctaatagca atcaaaaacc gcgaagttcc
    14521 ttatctacgc agagaaatcg gcgtggtgtt ccaagactat aaattattac caagaaaaac
    14581 agtatatgaa aatgttgcgt acgctatgca agttatcggc agaaaacctc gggatatcaa
    14641 aaaacgagta atggaagtgc tggaccttgt tggtttgaaa cacaaagttc gagtctttcc
    14701 tagcgaatta tccggtgggg aacagcaacg tgtctctatt gctcgggcaa tagtgaatac
    14761 gcctaaagta cttatcgcgg atgaaccgac aggaaatctg gatccagaaa actcatggga
    14821 aatcatgaaa ttattagatc ggatcaatgc ccaaggaact actgtcgtga tggctacaca
    14881 taacagtacg atcgtaaata cgattcggca ccgagtaatt gctatcgaaa acggccgcat
    14941 tattcgagat caagcggaag gggaatatgg atacgatgat tagaaccttt ttccgccatt
    15001 tattagaaag tatcaagagt ttgaaacgta acggctggat gacagttgct tcagtcagtg
    15061 cggtaacgat cacattgact ttagtcggtg tattcatggc agttatcatg aacgcaacta
    15121 aattagctca agatatagaa ggaaacgttg atgtctctgt attcgtagat atcggtacaa
    15181 aagacgaaga gatgaaaaag ctagaaaaag aattgaatga cttagatcat gttaaaaaag
    15241 ttgaattttc aagcaaagaa caggaattga aaaaaatcca aaacgaaatg ggtgattcct
    15301 ggaaattgtt tgaaggtgac aataacccgt tatatgatgt gtatgtagta agtgctactg
    15361 atccttctta tacaaaacaa gtagcagaag aagcagcaga tttgaagaat gtttctcgtt
    15421 ctgattacgg tggagcttcc tcagatcgga ttttccaaat cgctggtgca gttcggacat
    15481 ggggattagt tgcagcggca ttgctgctgt tcgtagcgat gtttctcatt tcgaacacga
    15541 ttcggatcac gattttgtct agacagcgtg aaattcaaat catgcgttta gtcggtgcaa
    15601 aaaatggata tattcgctgg ccgtttttcc ttgaaggtgg ctggatcggt ctgatcggtg
    15661 cgattcttcc gattttgatc atcacatttg gttatgcatg gtttttccaa ttgatcaatc
    15721 catcattatt acgttcccat tattcattga ttcatccaca aaatatcgtt tggaaaatca
    15781 atcttttaat ggtcggcatt ggtgtgatca ttggttcact tggctcgatc atttctatga
    15841 gacgtttctt gaaattctaa taccacaata taaataaaat gagaaagttg gacagtttcg
    15901 ttccagcttt ctttttttat tggctaggag aatagaagga agcggctttt ttccctttac
    15961 tttaaaaaac aacttgggta ttcttaagtt ggtagaagaa gaggtgaagc cgtgaaaatt
    16021 atcgttgaca atttttttac gatccttttg attatgaata ttttgctttc ctttatcatc
    16081 gtttttcgag aaagaaagga aactgctcaa acatgggcat gggtgctcgt tttgatgttc
    16141 attccagttg taggatttat tttatatatt tttttaggaa gagggatttc caaagagaaa
    16201 atctttgatt tgaagatcca agggaaaatc ggtaagaacc tggaaattga agaagacaaa
    16261 caggcattga tgcgagggct ttatcctcat ccgcctactg gacaagtaga tgtgaaacaa
    16321 ttgatctata tgctcacggt atttgaaagt acgctctata cgactaaaaa tgaaatcact
    16381 ttatttacag atggtcgtga aaaattcgat gcgctgattg aagatatcaa gcaggcagaa
    16441 gaccatatcc acttccagta ttatatttat cgcagtgatg cattaggtga agaagttcga
    16501 gatgcattga cagaggcggc aagacgaggg gtaaaagtca gagtccttct tgatgcatgg
    16561 ggttccacac aagtttcttc cagctttttt cagaatttga aaaaagcagg cggagaagtc
    16621 gcatttttct ttcctctatt tgttccgtat attaatcctc ggatcaatta tcgcaatcat
    16681 cgtaaaatcg tagttattga tgggaaaatc ggatatacag gtgggttcaa tgttggaaat
    16741 gaatatctag gattggtaaa gaaatttggt tattggcgag acaatcattt gcgtatttac
    16801 ggagaagcgg tgtatacctt gcaaaaccgt tttttgatgg actggaattc tcagcataca
    16861 aaagaagtag gctattctcc caaatttttt ccgtccattc actctactgg tgatatagct
    16921 gttcaaatcg tgacaagcgg accagatacc gaacatgaac aaatcaaaat gacttatttg
    16981 aaaatgattt cgttagccaa acgggagata ttgatccaaa cgccttatta cataccggat
    17041 ggatcgattc atgaagcact gaagttggct cttctttcag gcgtaaaagt tcatatccaa
    17101 atacctaaca aaccagatca tcttctcgtt tactgggcaa cgtattcttt cgctgcagag
    17161 ctaatcgagt atggagcaag gatcgaaaca tatgagaatg gatttattca tgcaaagacg
    17221 atgattatcg atggtggcat tgtttcagtt ggctcagcaa atatcgatgt tcgttcattt
    17281 cgcttggact ttgaggtcaa tacactggtt tatgatgaac gaatggcttc acgtgtaaga
    17341 aaagcttttt ttgaagactc gaaaatttct acgcatctca caaaagaaat gtatgaaaac
    17401 cgaggaataa tcatcaagat gaaagaagga ttagcaagat tgatttcgcc gctcctttaa
    17461 aacataaaaa ggacatgaga accatcaaca gatggagatc tcgtgtcctt ttctaacggg
    17521 gccatttctg agagtacgtc agaaatggag aaagcgtctc gcatgagcga aattaacttt
    17581 ggggtatctc ttgttttttg gggaaagcaa gaaataagct aatatatgct attaaaagag
    17641 acacatttca aagccagtat agcatagaaa cttttaatga gatagttttt tttacaatta
    17701 tgagaattta ttttgttatt taatgatttt gattcgtttt catcaagtaa tgaaaatgat
    17761 aaaataaaca tactttagga ttaaaggaga tttctaatga aaaaacttaa attattctta
    17821 ccaataatag gattagctat tcttttatca ggctgttcaa agtggattga tcgaggagaa
    17881 tccattacgg ctgttggctc ttctgcttta cagcctttag tagaaacagt tgctgaaact
    17941 taccagacag aaaatcctgg aaaattcatc aatgtacaag ggggcggaag cggaactggt
    18001 ttgtctcaag tacagtcagg agcagtcgac atcggaaact ctgatttgtt tgcggaagaa
    18061 aaatcgggga tcgatgcctc agcattagtc gatcatcgag tagcagttgt tgggatcact
    18121 cctattgtga acaaggatat tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta
    18181 tttacaggcg agatcaaaaa ctggagtgaa gtcggtggaa aagatcagcc agtagttata
    18241 ttgaaccgcg cttcaggaag cggaacccgt agcacgtttg aaaaatgggt attggacgga
    18301 gaaacagctg ttcaggcaca agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc
    18361 gacacacccg gtgcaatcag ctatgttgct ttttcttatg tttccgatga tgtagatacg
    18421 ttgaatgtta acggtgtaga accgacagat gaaaatgtga caacgaacaa atggacgatt
    18481 tgggcatatg agcatatgta cacaagagat catccaaaaa aactgacaaa agaattttta
    18541 gactatatct tatctgatga agtacaagat aacatcgttg gagaactagg ttatatccct
    18601 gtttctcata tgaaagtcga acgtgattgg caaggaaata tcgttaaaga gtaatcttta
    18661 cacaaaattt acaaacttag ctaaactttt acatgttatt aaaaccaaat tgatgttcaa
    18721 tttgtacact gagtgagtat gttaaacctg attaaggggg agtcatctgt ggaagatgtg
    18781 aaaaaagtat tattaacaaa atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc
    18841 agttttttat gtatcgcgct gatcgtgttg gttgtattat ctatttttta ttttgtagct
    18901 agtaaaggat tggccacctt ttttactgat aagatcaatg tatttgattt tctgtttggt
    18961 acagattgga atccaagcca aatcggagca aatgggaaac caatggtagg ggcattgcct
    19021 atgatcacag gttcgtttat tgtgaccttt ttatctgcta tcgttgccac gccatttgcc
    19081 attggtgcag cagtattcat gacggagatc tctcctaaaa acggaacgaa gatcttacag
    19141 ccggtcatcg agctgcttgt aggtattcct tctgtcgttt atggttttat cggtttatca
    19201 gttatcgtgc cttttgtcag aagtattttt ggcgggactg ggtttggtat cttagctggt
    19261 acatttgtgt tgttcgttat gatcttgccg actgtcacaa cgatgactgt tgatgcatta
    19321 aaggcagtgc cacggcacta tcgggaagct tcattagcgc ttggtgccac aagatggcaa
    19381 acaatctaca aagtcgtgct acgagcagcc gtgcccggga ttttaacagc agtcgttttt
    19441 ggtatggctc gtgcgtttgg tgaagcctta gctatccaaa tggtcatcgg taatgcagca
    19501 ttgatgccaa caggtcttac tactcctgct tctacattga cgtccatctt aacaatggga
    19561 atcggaaata caatcatggg aacagttgaa aataatgtgt tatggtcatt agcgctgatc
    19621 ttgctattga tgtcattatt ctttaatatc gtgatccgta tgattgggaa gaaaggagag
    19681 ctgaaataat gaacgcaaaa cgctcagata aaattgctac aggtgtttta tatatagttt
    19741 cggggatcat cgtattgatt ttagcagctt tactacttta tatcttagtt cggggaatac
    19801 cgcacatttc atggtccttc ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa
    19861 tcgggatcca gctatttaac tcgatttatt tgcttttgat cacgatgatc atcagttttc
    19921 ctatttcttt aggtgcgggt atctatcttt cagaatatgc tggaaaaaac tggctaacag
    19981 atgtgattcg cacgtcgatt gaaatcttga gctcgttgcc ttctgtcgtt gtcggtttat
    20041 tcggtttctt ggttttcgtt attcaattcc agtatggttt ctcgattatt tctggtgcat
    20101 tggctttgac tgtattcaac ttgcctcttt tgactagaac agttgaggag tctttacaag
    20161 cggtccatta cacacaacga gaagcaggat tggccttagg tttgtcacgc tgggaaacag
    20221 tgataaaagt ggtggttcca gaagcgacac cagggatttt gactggtgtg atcctaagtt
    20281 ctggaagaat ttttggtgaa gcagctgcat tgatctatac ggctggacaa agtgcacctg
    20341 cgttagattt tacgaactgg aatccattaa gtgtttcaag cccgatcagc attttccgtc
    20401 aagctgaaac attagctgtc catatttgga agatcaatac agaaggcacg atgcctgatg
    20461 gtgtttctgt ttcggctggc gcttctgccg tgttgattat tgctgtttta ctgttcaact
    20521 tcggcgctcg tgcgattggc aaacgattat accgaaaaat gacttcagcc taaggagaag
    20581 aagcaaaatg aaaaaatata actggaatga aacaaatgtc atcaccatgc caaaagagaa
    20641 agaagtagca ctatatacgg atgatctaca tgtctggtat ggcgacaatg aagcaatcaa
    20701 aggagtggat ctggaatttg aaaaaaataa gatcactgca ctgattggtc cttccggctg
    20761 cggaaaatct acgtatcttc gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa
    20821 aatcactggg aaaatcatgt atcaaggcgt agatattaat gcgcctcaag tggatgttta
    20881 tgagatgcgc aaacggattg gcatggtttt tcaacgtcct aatccgttca gcaagtcgat
    20941 ttatgacaat attacatttg ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga
    21001 tgaaatcgtt gaaacaagct tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt
    21061 ggacaaaagt gccttggctt tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc
    21121 gatcgcgatg aaacctgata tcttgctgct agacgagccg gcaagtgctt tggaccctat
    21181 ttcgacagga acggttgaag aaacacttgt aaacttgaaa gaagactata cgatcatcat
    21241 cgtgacgcat aacatgcaac aagcagctcg tatcagcgac tatactgcct ttttctattt
    21301 aggaaaagta atggaatatg acaaaactaa caagatattt accagaccaa aaattcaggc
    21361 aaccgaagat tatgtgtccg gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga
    21421 gattatttca tctaaagatc ttcatctgta ttatggaaag aaagaagcac taaaagggat
    21481 cgatctaagc ttcaatcaag gggaaatcac tgcgatgatc ggtccttctg gttgcggaaa
    21541 atccacttat ctgcgttctt tgaaccggat gaatgacctg attccgaatg taacgatcac
    21601 cggaagtgtt ttatataaag acaaagacat ctatggtcca aaaacagatg ttgttgaact
    21661 aagaaaagaa atcggcatgg tattccagca gccaaaccca tttccttttt ctatctatga
    21721 aaatgtcatc tatggattga aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt
    21781 agttgaagaa agcctgaagg cagcgtctgt ttgggatgat gtgaaagaca aattgcataa
    21841 aagtgcttta tctttatccg gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc
    21901 agttaatccg gaaatcatct tattggatga accaacaagt gcgcttgatc ctgtttctac
    21961 tgggaaaatc gaaagtatgc tgttagaatt aagagagcgg tatacgatga tcatcgtgac
    22021 ccataatatg tctcaagctt cacgtatttc agataagacg gcattctttt tagatggtca
    22081 cttgatcgaa tacaatgata cgaagaagat attcatgaat ccagaaaaac aagagacaga
    22141 agattatatt tcaggtcgat ttggataagg aggaaacgga atgctacgta cacaatttga
    22201 agaagaattg ctgaatctcc ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc
    22261 cgtgcacaag tcagttcgtg catacatcaa acacgataaa atcttagccc aagaagttat
    22321 cgaaaacgat ataaatatca ataacatgga aacacgcttg gagaagaaaa gttttgaaat
    22381 gatcgcattg caacagccag ttacaactga tttgcgtatg atcattacgg tcatgaaagc
    22441 tagctcggat ttagaacgta tggccgatca tgcggtgtct gttgctaaat ccacgattcg
    22501 cgtaaaaggg cagacgagaa taccggaaat cgaaaaagag atctccgata tgtccgatta
    22561 tgtgaaaaaa atggtggaca acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc
    22621 acgtacgatc gccaatatgg atcaaagagt caatgactat ttcaatcgaa tctataatgc
    22681 aacaatcaaa aatatgcagg aaaatcctga gacagtcatc agtggaacag actacttgaa
    22741 tgttgccagt tatctagaac ggatcggaga ctatgtgaca aacatctgtg aatggatcgt
    22801 ctacttggct acagggaaaa tcactgagtt aaatacgaac cacaatgaga ttttctaaac
    22861 tgaagctgtg attatgccgt ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa
    22921 aagctgttct gcatcaagta ataagaacag tcaaacaaaa aatagctcct catatttttc
    22981 gtttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt cgggaaaggg
    23041 tttgtgacaa aacatgtcac aaaccctttt catcatttca tagaaaggat aaagaatgca
    23101 aaaaaaaatt agcatcatca ctatattttt tatttgtgtg cttacttcat gggttattca
    23161 gcatcaagcc gctttatatg aagtacctgt catcgagata gaaaaagtac gaataaaaga
    23221 ggatcatcaa ttgattacag gaaaactgat gaacacggat caaaaaggag aatcgattta
    23281 tttatcggtt ccttatcaaa aaaatcaaat agaaacagca aatataaaag cgagacaaat
    23341 gtatctagtc caaatgcatg gagatgaatg gcagctagta gcaaaaaaaa atgatggctg
    23401 gcttttcttc ttcacaagta tcttcattgg cgccatgttg cttattggtg gaaaacaggg
    23461 tctatttgct ttaggaagtc tcatcatcaa tatcgtttta cttttacttt tgttgctcat
    23521 ctttactaaa acagaaggga tttctctatt aaatatatct atcctgttcg tcgttatagg
    23581 gatgattatt agcatattgg ctttagatgg atggaataga agcagtataa tcaaaatttc
    23641 agctgcagtt acgagtgttt ttttagcatt ttttatttgt cttttgacaa tgaatcattg
    23701 gaaagaccaa ggactgcgct atgaggaact gaattatctg acacgaccgt atcgttctgt
    23761 ttttctttct agcgtactga ttggaacagc tggaggaaca ctcgataccg ttatcacagt
    23821 cattgcgaca ttagaagaat tgactaagcg acaaccagaa ataacagcga aacagttatg
    23881 gctttcagga aggcaagtgg gtcgagatgt gattggctcg atgaccaata tccttttgtt
    23941 cgtctatatc agtgggtcag ttccatcgct tcttttatat ttaggaaatc aatggtcgtt
    24001 caaagaaacg atagaacagc atttatcatt ggaattttta cgcgtcattg ctggcagctt
    24061 aggaatagta ttatcgatcc ctatctcggt cctctttttt ctgactgtaa ggaggctgaa
    24121 acgatgaatg tacttattat acttgttggg attttagcaa tcagcgtgct acttattggc
    24181 ggtacgcaag gtatgtatat tcttttaggc ttattcatca atttagggat ctttttcctg
    24241 ttgttattcg gttatcatca gaagtggccg atactggcat tgtcggtcat aggattttta
    24301 ttgattgctg tggttatctt attttttatc aacggttata atctaaaaat gcgtgcagct
    24361 tttgtgagta tactgatctt tttattttgt ttcctactat tgcttcctat cactgatttt
    24421 ttagcaatcc aaggttttac atcggtagaa ctagaagaat tatctggctt agataagact
    24481 ttagcgattg attttagatt acttacgaga tcgttgcttc tgattagtct tagtggtgct
    24541 gttttagatg cgagtgtagc aatttctagt gggacattcg aagtatatca ggcaaatccg
    24601 caattatctt tttaccaatt gcgccattct agtttcgcta ttgctaaaaa aatattggcg
    24661 tcaacagtaa tgacacttct ttttgcattc atgggaagtt ctttagcgtt gatcctctgg
    24721 tttattgatt tagacattcc ttttcagcaa gtgatcaatg aaaaatcatt tgttctagaa
    24781 tatacgatgg ctattcttac cacattgtcc gcactacttg ttcttccttt aacctgcgtg
    24841 actacagcat atctctttac aaaaaagaaa gaacaactca agatggagta aaagttacaa
    24901 cttaagtcct atgacatttt tactgaatca gtgcataata tggatgtaag gaaaagcttg
    24961 caaacaattt tgcttaagga ggcaatttcc atgaaagaaa gagaacgtat tttagattta
    25021 gtgaaaaaag gaatcctttc gactgaagaa ggcttagatt tattagaaag catggcaact
    25081 gaaaaagacg aaaagcaaat caaaaaagaa gcagacaagg taactgctag tcataaagaa
    25141 aaagatcagg caagtcaatt gatcgataaa cttgaaaacg gcgaagaaga aatttctgag
    25201 ccagttgatc caaaggaaag agaaagacaa gatcaagaaa acttagaaaa gatcttagat
    25261 gaactagcaa ctgaagcgaa taaaacttcg gcgcgtctag atgaagtaaa tgctcaattc
    25321 gctgacaata aggcagcacg caatgagaaa caggaagcat tgatgcagct gaatacaaaa
    25381 gaagaattag gcgagttgac agaagaagaa ttagcacagc gtcagacgtt agaagcagaa
    25441 atcaaagaat tagaagctag tggcgataca ctgttagaag aacaattgaa attagaagca
    25501 gaattaaaag atatccgtaa gaatcaatgg tctgagaaaa aagaaacgtt tactgataag
    25561 tttgaattgc cagatgattg gaaagatcaa gcaacagata cactgaatca agtaggcgaa
    25621 aaaatgtcag aagctggatc acagttaggc aaattcttga agaaaacatt ccaaactgtt
    25681 tcagaaacag tgaatgacaa catggaatgg aaagatgtca gcttacgtgt ccctgggatt
    25741 gcgacaacga aatttgagca tgaattttac tatgaagctc ctgcagcaag tatccttgat
    25801 atcaaggcag caaacggaaa cgtgacgtta aaaacgtggg acagcaacga tgtgaaagtt
    25861 gaagctaaga tcaaacttta cggaaaaatg ggtgctgaac catttgaagc attctctgaa
    25921 cggagccaga ttgaggttaa tgaagatcat atctccttcc aaattccaaa taaacgtgtg
    25981 cgtgcagacc ttgttttcta cttacctaaa cgagtatacg accacgcagc tattaaactt
    26041 ctaaatggca acatcatgat tgaaacattg gaagctaaag atatttatac aaaatctacg
    26101 aatggtaaca tcatcgtgga ccaattaact gcaacgatgc tggaagtaga aggtgtaaac
    26161 ggcaatatcg atattcgaaa cgggaacatc ttagattcta ttatcgaaac agtaaatggt
    26221 acagtgacat ttggtgcgac agcagaaaac ctttctgtgt ctttggtaaa tggtgatgta
    26281 cgtcttacga ttaaagaaga taatttgaaa aaagtagaag caagttcagt gaacggaaat
    26341 gtcaaagtcg ctttaccaga tggcatcggt ttggaaggac atgctaaaac aagtcttgga
    26401 agtatcaaca gccgtctgtc caattacgaa gtagttcgtg agaaaaaaga acggacaaac
    26461 caaatgttgc aattccgtcg tgtttcagat ggtgaaatcg cgcaagtgca actttcaacg
    26521 acaacaggaa gtatctattt aaaagataca gataaataaa gaggttgtga aagagatgtt
    26581 cagccttgag caataagaag cgattttgta aaatagcttc ccctatttta caaaattgtg
    26641 ccttattgcc gatagtctat ctcttgaaca ccgtttacca agagattatg aacctgccaa
    26701 ttatcgccga gtcacaagga ataatttcag aaaaagctcg tcacgtttta tgaatatggt
    26761 aatttgtgac cgagaatttt gcagaaagac accgattaag aagaaggttg tcacaacgat
    26821 tttcttcatt taaaatagta gaacagaggt gagacatgat gaaaaaaaag ttgacaaaat
    26881 ctaataaaaa tgttgttttg acagggactt tagcaggaat aggagaatac atcgggattg
    26941 atccgactgt tatccgtgtg ctttatgtat tcctgagctt agttgctttt ggaagtccaa
    27001 ttattttata cattttatta gctttgatta tcccatctgc gcgttctgca cgaacaaact
    27061 atggacataa caatgcatat tatgaaaaaa acaattatcg tgaacaaact cgtgaacaaa
    27121 caaaaaaacg caaagaagcg gaaaaaatcg atgatgacga atggagtgac ttttaatgtc
    27181 gtactttcaa cgtattttag ttaatacgtt aacattcata tcattggctg ttctttttcc
    27241 tgcgatggtc catgtgagca gtatttggac ggccgttctt gccagcttcg tattgtctgt
    27301 gttgaatatg tttgtcaaac cgattttgac gatactgtcc ctgcccttta cattagtcac
    27361 attgggattg tttacgtttg ttatcaatgc agcgattctt aaaatgacct ccttttttgt
    27421 gggagcagaa cattttagtt tttcttcatt cggtgcagcg ttgttagtag ctatcttgat
    27481 gtcgcttgtc aatgtaattg tcagcgaaca taacagtaga aaataaaaga aagctgtgcc
    27541 gaactatcgg cgcagttttt ttatttagaa tcaggaatgc gttttctatt acattggtaa
    27601 ttaaataaaa acgttttttt taattggtag tacttttggc tagacaatga taaaatgata
    27661 gagaacactc taatagaaat gaggtagcat gaatgtcaga agttgtaaaa gttagccaat
    27721 tagtgaaaaa attatctttg gaaatcgtga caggcgacga gaaaagctta gaccgtgtca
    27781 tcgtaactgg ggacatctca cgcccaggac tagagttgac tggttatttt aattattatt
    27841 cccataatcg tttacagcta tttggcagta aagaaatcag ttttgcggaa cggatgatcc
    27901 cagaagagcg tttgatcatc atgagaagat tatgtagtga agatatgccc gcatttatta
    27961 tttcaagagg attaccagct ccagaagaaa tgatccaggc agcaaatgaa aatgggatag
    28021 ctgtactgcg ttctcccatc tcaacttctc gtttattagg agaattatcc agttatttag
    28081 atggtcgcct tgcccctcga acaagtgtcc acggtgtttt agtggatgtt tacggattag
    28141 gtgtactgat tcaaggtgac agtgggatag gaaaaagtga aacagcgttg gagttgatca
    28201 aacgcggcca tcgattgatc gcagacgatc gagtagatgt ttatcagcaa gatgaattaa
    28261 cggtgatcgg agaaccgcct aaaatcctgg aacatctgat tgaaatccga ggaatcggga
    28321 tcattgatgt aatgaatctt tttggtgcga gtgcggtacg tggctctatg caagtccagt
    28381 tggctgttta tctggaagca tgggcaaaag ataagaaata cgaccgtctg ggctctgaag
    28441 acacgaccgt tgaaatcgcg gaagtgggca ttccacaaat aaaaatccct gtcaaaacag
    28501 gacgaaacgt tgcaatcatc attgaagtag ccgcgatgaa tttccgtgca cgtacaatgg
    28561 gctttgacgc aacgaaaaca tttgaagaaa gattaagtcg cttgattgaa gaaaactcag
    28621 gcaacgacta gcaaggagtg acaatatgtt agcacaaatc aatcgagttg cttttgagct
    28681 tgtagggatt cctatctact ggtatgcatt gatcatcgta tcaggtatca ttatcgctat
    28741 gtggcttagc agcagagagg ctgttcgggt aggattaaaa gcagatgatg tgacagattt
    28801 tatgttgtgg ggattgccta tctccattat tggcgctcgc ttatattatg ttttatttga
    28861 tcttccccag tatatagctg atccaatcca aatattcaat atccgttcag gaggcttagc
    28921 tatttatggc ggactgattg caggcgcgat cacgctgtat ttttttacta aatatcattt
    28981 tatttctttg tggacttttt tagatatcgc tgcaccaagt gtattattag cacaggcaat
    29041 cggtcgttgg ggaaatttca tgaaccacga agcatatgga ccagacacga cgcgaagctt
    29101 cttagaaagt ctgcatttac cgcaattcat cattgataat atgtatatcg aagggatcta
    29161 tcgtcaacca acatttcttt atgaatcact ttggagtttg attggattta ttttgctttt
    29221 gtttttacga aagaaaccac accttttgaa aaaaggcgaa gtccttttat gttatctaat
    29281 gtggtatagt ttcgggcgtt tctttattga aggattacgt acagacagtc tttacttttt
    29341 aggtgtgatc cgtatttctc aattattatc tgctgtgtta tttgtcggta cattgattct
    29401 atttatttgg cgcagaaaaa aaggaaattt accggattat gaccgctcat taggaaaaaa
    29461 tcaacaaatt atctgatttt tagagcgtta aaaatgaaaa aaatttcagg agtggtaaaa
    29521 tgaattatag agtagcggtt ttaggaccag gctcttgggg tactgctttg gcacaagtcc
    29581 tcgccgaaaa cggacatgac gttcggattt ggggacatcg tgcttcacaa gtagaagaaa
    29641 tcaacaccca acacacgaat caacgttatt taccagatca ttatctaccc gattccatcc
    29701 aagcattcac caatatggaa gatgcagtaa aagacgcaga tgcggtgcta ttcgtcattc
    29761 caacgaaagc aatacgttct gttgcaaaag aactagtgcc taaattgaat acaaagccag
    29821 tgatcatcca tgcaagtaaa ggattagaac agggaacaca taaaaggatc tctgacatct
    29881 tgttagagga aatcccagca gaaaaaagaa aagctgttgt tgttctttct ggaccaagcc
    29941 atgcagaaga agtagcaaaa catgacatca ctacgatcac agctgcaagt acagatgcaa
    30001 aagcagcaaa atatgtacaa gagctgttca tgaataatta ttttcggatc tataccaatc
    30061 ctgatgtgat cggtgtagag atgggggcag ctttgaaaaa tattattgct attggtgctg
    30121 gcgctattca cggcttaggg tttggcgata atgcaaaggc agcaatcatg acgcgcggat
    30181 tagctgagat cagccgttta ggtgtagcaa tgggtgccaa cccgctgacc tttatcggat
    30241 taagcggaat aggcgatcta gtcgttactt gcacaagtgt tcattctagg aactggcgcg
    30301 caggcaactt gttaggacaa gggcagcccc tagaagaggt gctagccaat atgggaatgg
    30361 tcgttgaagg tgtgaatact acccaagcag cgatggaact agcccaaatg atggaaatcg
    30421 aaatgcccat cactcaaaca atctatgaag tgctgtatga acaaaaagaa atcaaaacag
    30481 ccgcaaaaga aatcatgtta cgtgatggaa aaaaagaaaa tgaattctca ttaacaattt
    30541 tttgaaggag cgaatgtata tgaaagttaa aaaagcagtt attccagcag caggattagg
    30601 aacaagattt ttaccagcaa caaaagctat ggcaaaggaa atgttgccaa ttgttgataa
    30661 accaacaatc cagttcatcg ttgaagaagc gttgaaatca ggtatcgaag acatcttgat
    30721 cgttacagga aaagctaaac gaccaatcga agatcacttt gattcaaata ttgaattaga
    30781 aacaaaccta agtgaaaaag gaaagaccga attattgaaa ttagtagaag aaacgacaga
    30841 tgtcaacttg catttcatcc gtcaatctca tccaaagggt ttaggacatg ccgttcttca
    30901 agcaagagcc tttattggaa atgaaccatt tgtcgttatg ctaggcgatg atataatgga
    30961 agacgaagta ccattgacac agcaattaat cgatgattac gaacgtactc atgcttctac
    31021 gatcgccgtt atgcaagttc ctcatgatga aacttcaaaa tacggaatta tcaatccagg
    31081 agaagtattg gaagatgggt tatacaatgt caaaaacttt gttgaaaaac cagatccaag
    31141 caaagcacca agtgatttag ctattattgg acgttactta ttgactccag aaatttttga
    31201 tgtattgtcc gagcaacaac caggagccgg aaatgaaatc caactaactg acgcaatcga
    31261 tacattgaat aaaacacaac gcgtatttgc ccgtaaattc acaggtaaac gttacgatgt
    31321 cggtgacaaa tttggtttta tgaaaacaag tattgaatat ggtctaacac atccagaagt
    31381 aggtgcacct ttacgtgagt acatcctgtc tttaggtaaa acattagaag cagaaggaag
    31441 caagatcgat cataatccaa aaggaataac agaaatcaaa gaagaaaaga aaaaataacc
    31501 cttttttcta acgagcttca gctgctaatt gaataaaaag tagttgaagc tcgtttttat
    31561 ttgtttaaaa aacacgaaaa tgctatcctt atagaaaaga gagacaagaa gggagtttga
    31621 tcatgtcagg aggagaaatt gcaggattga tcgcagcaat cgcctttgcg atacttgtcg
    31681 tttttatcgt tcgtgtgttg ttgcaagttt ctaaaacttt agaaaaagta gatcagactg
    31741 tagcagaagc aaatacgacg atcgaaatcg tcacaaaaga cgtagatctt ttgtctagac
    31801 aagtagaagg cttactggtc aaaagtaatg aactgctctt ggatatcaat ggaaaagtcg
    31861 caacgatcga tccattgttc acagcagttg ctgatttaag tgaaagtgta tcagaactta
    31921 atcattctag taaaaacatc gcgacgaaag tcggcggaat cggtaaaacg acagctaaag
    31981 cgacggttgc cggaaaagtc ggtgggacag cgatgaaatt ttttaaaaac aaaaaacata
    32041 ctgaaacgac aggaggaaaa taaaaatggc taaaaaaggt ggatttttat taggtgcagt
    32101 agtcggaggc acagccgcag caatcgccgc gttattgtta gcaccaaaat ctggtaaaga
    32161 acttcgggat gaattagctg cccaagcgga tgatttgatg gatatggctt cagattacac
    32221 agatatggcg aaagaaaaat cgactgagtt aacaggtatt gcaaaagaaa aagcgcaaga
    32281 tctttctcaa caagcaggtg atctagcagg tagtgtcaaa caaaaagtaa gtgaatcagc
    32341 agatgaagca ggaagtgaat ctgacgatat cttgttaaat cttaaagaac aatcagctga
    32401 cttatctaat cgtttcaaaa aaacggcaga agatatgaaa aaacctgcag atgaattagg
    32461 aagtattgct aaagatactt cagaagatat catgattgat gtaaaagacg ctgctggtaa
    32521 agcaggagat actgtcaatg aaggaatgtc agaagcaaaa ccagttgcag atgactcaaa
    32581 agaaatgatg aaaatggcaa aagaagatgc gaaagaagct aaaaaagaaa taaaagatac
    32641 aatgacagat tcatctacaa atcactaaaa tcacaaattt atagaataaa aaggtgggag
    32701 cggactagct ctcacctttt ttactcttat ttttctaaaa caagtaattc ttttggtgta
    32761 gtcgtgaatg gcacacagcc atcgcttgtc acatatacac agtcttcgat acgtacccct
    32821 actttttcag gaatatagat tcctggttca agagagaagc acatcccttc ttcgattact
    32881 aagtcatttc cttctacaag ggaagggaat tcgtggacgg ttgttccgat cccgtgacct
    32941 aaacggtgat tgaaatattc gccgtagcca tagctgttga tcacgtttcg tgcgatttga
    33001 tcaagttcac ctgctgtcac acctggacgg acggcttctt gtgcggcaag ctgtgcttca
    33061 agagtgatgt tgtagatttt ttcttggaag tcggttggtt tttgataagc aattgtacga
    33121 gtagcatcac tgcaatagcc attccaaaca acgccaagat cgaataacac aagttcattc
    33181 ggtgaaatct tcgtatttcc tggtgtacca tgagggcttg cagcatttgc tcctgcaagg
    33241 actaatgtgt cgaaagacat ttgtgaaaca ccttgttttt tcaattggta ttcaatttct
    33301 gcaatgatcg cttgttcagt cacgccttct ttcactgctt taaagccaat ctcaaatgca
    33361 acatcggccc atttaccagc ttcgatcagt ttgtcttttt cctctagagt tttgatcagt
    33421 tgtagacgtt ggatgatgga agttagatca gtgtaagaat ccgttcccgt caagatatca
    33481 gagatagcat cgaagcgctc gacagtcaag gcgttctttt caatccctac attgccaggc
    33541 tgaccatagc gagcacgaag ttcttttccg atgatctccc aagggttttc gctgtctaaa
    33601 tagccacgga catcatacgc ccaactactg ttttgagcat cttcaacttc caaagcagga
    33661 gtgaaaagga aaggatcttg ttcaagaggg ataaaaagag ctagtacacg ctcatgagga
    33721 tcactttcgt atccggaaaa gtaagcgatg tggccagggt cgctgatata agccaattcg
    33781 acttggtgtt gtgccatcca ttgacgtagt tcattgattt ttacgttatt catttggcaa
    33841 cctactttct aaattaattt tgtattcaat aattgtacca ctgatttatt aaaagaccaa
    33901 cgttctaaaa actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa cggttgcaat
    33961 tcttgagatt atttgatatt ctattttaga aatgtaagac gtattttcag aaaacatata
    34021 aaatatgaat aggagaacac aaatggaaaa gcaaacaatc actatctatg atgtagcgag
    34081 agaggcaaat gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc caaacgttaa
    34141 accagcaaca agaaaaaaag tcttggaagt tatcgatcgc ttggattatc gtccaaacgc
    34201 agttgcgcgt ggcttggcaa gtaagaaaac aacaacagtt ggtgtaatca tccctgatgt
    34261 cagcaatatg ttctttgctt ctttagcacg tggtatcgat gatgtggcaa caatgtacaa
    34321 atacaatatt atcttagcaa attcagatgg caacgaccaa aaagaagtca atgtattgaa
    34381 taacttactg gctaagcaag tggacggcgt gatcttcatg ggtcaccata tcacagacga
    34441 aatccgtgga gaattttcac gttcaaaaac tcctgttgta ttagctggct ctattgatcc
    34501 agatgaacaa gtaggtagcg taaacattga ttatgtatcc gcaacaaaag atgcagtaaa
    34561 caaattggca aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt tgatcgatcc
    34621 catcaatgga caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa ataacctacc
    34681 atatagcgaa ggattgatct ttgaagcaca atacaacttc aaagatggtc tatctctagt
    34741 cgatcggatc cataatagcg gtgcaacagc tgtctatgtt tcagatgatg aattagccat
    34801 cggtattttg gatggtttat tagaccgtgg cgtgaaagta ccggaagaat tcgaaatcat
    34861 cacaagtaac aattcactac tgacagaagt agctcgtcct cgtttaacaa gtatcacaca
    34921 accattatac gatttagggg cggtatctat gcgcctattg acgaaaatga tgaataaaga
    34981 agaagtcgaa gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag gatctacaaa
    35041 ataataaaag gacaaccatt cagaggttgt gtgcctgccg tttaactctg cgttacaagg
    35101 agcaatttca aaaaacagca tctcatgttt gatgaatatt gtgactcgtg attcggagtt
    35161 ggcaggagaa caccgtttat ttgggaaaag gggttatgac aaaattttgt tataatcctt
    35221 tttttgtgtc ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta tataaaacaa
    35281 tccgtgtata gatgctgcat tttgttcacc accatcaaaa aaataaggga ctgtgacaat
    35341 actattgtca caatccctta ttactgtgta ttctattaaa tcaatcatct ttctcatctg
    35401 attctttagt tgcttgattc gctcttgcat aagctgaagc ggtgttccag taatctgtat
    35461 agttttcatc ggtaccgcca acgccaaatt taaaggcgct tttcttcggt ccatttttcg
    35521 cccatagcga ttcaactgtt tttcctggtg tttggatgga ttttttattg acagtaactt
    35581 ttccaggtgt ttgaccagta aatccagata cttttttctt catcacatca gatgataatt
    35641 cgaatttctc atcagtgcca aaaatgtcag gttttgcttg gtaagcttga ttgatcagat
    35701 tggcaagata attagccgaa cgtatccttg ctttgctgtc cattccagta ttgtcatcgt
    35761 gccctgccca gctactgatg gtaatagacg gagtagagac aattagccat gaatctcggt
    35821 attcattggt agaaccagtt tttccgaccc aatctgcttt tcctagattt ccgtttaagc
    35881 ttgagatggc atctttgaat ggtgtagtga tttttgcatt gatcacacta cgcatcatgt
    35941 cattcatgat cgatgccgtt gcttccgaat agatccggac agagttgctt tcgtgtttat
    36001 aaattacatt tcctgcgtta tctgtgatgg aatcgatgat atagccttct tcatagacgc
    36061 cgccgtttgc taaagcctga aatccgttgg tctgttgaag cgtcgtgaca tctactgtac
    36121 ctaaaggagc agattcaacg ccccaattgt catttgccgg gtagttcatc tttgccaagt
    36181 agtgctcgta agcatattgt ttcgatccac cggaattcaa cacatcttga tataagtgat
    36241 aagccgggat attgttggac cattctagtg actcacggac ggtttggaag gtgttcgatc
    36301 cttcgttagt agcattgacg attttctcgc cagcattttc tccttcttgc caagttgttg
    36361 cataatctga tacacgggat tctgatccga taagccccat gtcgattgca ggtccataaa
    36421 caagaactgg tttgattgat gagccagctt gacgttctgt atcgaaggca tggttatttt
    36481 gattctgact gtaattccgt ccgccaacga atccgtagat gcggccagtt ctgttatcca
    36541 tcaatacatt tccggtttct acttgactgc cagcaccatc atctaacatg tatccataat
    36601 tttcaacgcc attttgcaat gcagcataga catctttatc gattgtcgaa tggattgtat
    36661 atcctttatt ttggatcgtt tgctgtgcct tttgataata agcgtcactg accgatgaat
    36721 cagacatatc agcgttgtct ttttcagcca attgttgtgc aatgattctt gttgcttcat
    36781 tcatcacagt ataatacaag aattctctgt cagtctgttc tgcgatttgt tgtggtagaa
    36841 agtcttttgt aaggtcatag gcttttgctt cttcgtattg ttctttcgta atttggcctt
    36901 cacgatacat actgaataaa acaaaatctt ttctggcaag gccggcagaa agatcttctt
    36961 ttagcgcgcc tgtgttcgtg tatggactat acgtgatcgg gctttggggt aatccagcga
    37021 tataagcagc ttgcggcagc gtcacatctt ttgcatctac accaaagatt ctttttgcag
    37081 cttcctggac tccagcaatg ttttgtccct tattattacg accaaatggt gagacattca
    37141 aatacgtagc aatgatctca tcttttgaaa agtatttttc tacttgtgca gaaagaatga
    37201 tctcgtttgc tttacgtttg aatgttgttt catctgtaag gatctgctgt ttgactaatt
    37261 gctgtgtcaa agttgatcca ccagaagagc caataccagt agcttcagat actaatgctc
    37321 gtaaaacagc tttaggaacg taaccttggt gtttatcgaa gtattcatcc tctgtgctga
    37381 taattgcagt tttcaataaa ggtgaaatct tatcagatga aatagtcgtg cgcatcagat
    37441 ctgtctggat ttttgatatc tctgtattat ctgcataaac aatctttgac gtttctgtaa
    37501 tgtttcctag ttctgtctgc agtgcttttt tagtcggcaa ttgtgtgtct tcgacgagat
    37561 aggcaaaata gccagcgcct attccaatac ctagagctgc gaacatcaaa agaagaacag
    37621 taataaaaac agtcaatgat tgaaaaactc taaaaataat cttaggaaca aaccattttt
    37681 ctttttttct tctattctgt ttttttcgag tatttttgcg tggcaaaagg gtcacctcaa
    37741 ctaatggttt tatttcgcta attatagcaa ataatagaac aaaaaaacag acaaggctgt
    37801 ttttggcagg aatttctttt ttaaaagagt taaaacgtga gaaaatgatc tttattataa
    37861 aagagttctt aagcttttct ttagagaaaa tttcagttac tatggagaac agggcaaaga
    37921 aaaatcaatc attttctttg tatatcatct taccaatata taggaattgt tagtaacaat
    37981 tgcctttcaa ggaggaatcc atccatgtta ttaggctcac acgtcagcat gagcggaaag
    38041 aaaatgctgt taggagcagc agaagaagca gccagttatg gatcttcgac ttttatgatc
    38101 tatacaggcg cccctcaaaa cactagaaga aaagccatcg aagagatgaa tattgatgcc
    38161 ggaaaagcgt acatggcaga aaaaggtcta acaaatatcg tcgttcatgc cccttatatc
    38221 attaatttgg ggaatacgat caaaccagaa atgtttcctt ttgccgtcca atttctgaga
    38281 gaagagattg ttcgtgcgga agctttaggc gctactcaaa ttacacttca cccaggtgct
    38341 catgtagggg caggaacaga agccggaatt gctagaatta ttgaaggctt gaatgaagtt
    38401 ttgacaaaag aacagacggc acaaatcgct ttggagacaa tggcaggtaa aggtacggaa
    38461 atcggtcgaa catttgagga attagcgcaa atcatcgatg gagtaaaatt gaatgaaaaa
    38521 ttatccgtta cttttgacac ctgtcatacg aatgatgccg gttataatat taaagaagac
    38581 ttttcaggtg taatggaaga gtttgataag atcatcgggt tagatcggct taaagtactc
    38641 catatcaatg attctaaaaa tccgcaaggt tcgcataaag accggcacgc caatattggt
    38701 tttggaacaa tcggattcga cacgctgaat aagatcgtcc atgatccaat gtttgacaat
    38761 atttcgaaaa tcttggaaac tccctatgta ggcaaagata aaaagaaagc ttacgcacca
    38821 tatggaaaag aaatcgccat gttcaaagcg caaacattcg atccagaagt gtttcctgag
    38881 ttattagcag aagaagtgat actctaagat tttctatctg acagcagcaa aaaaggacca
    38941 ggcacattgc cttgtccttt tttgtttaag aaacaaagga gtactttttg cagtcttttt
    39001 catcatgcat cttctccccc ctctttttaa atttagacaa acaaggtata ctggtagaaa
    39061 agtaaaaaaa cgaaaagttt cacaagcaag tggcaaaacg tgattggaag gacgaaaaga
    39121 tgctgaacac tttaaaaccc ttgatcaacc aactaaaaaa gaaacataca tactttattc
    39181 ttggcatagc cctattattt acaattattc gtttgtattt atatagtaaa gcaatctatg
    39241 gaacagacat gtcggcaacc tatgatgacc agctgctgat tcgctatgct caaaatattt
    39301 tggacggtaa atggctaggg gagtatacga ctacaacact ttccaaagga atctcctaca
    39361 gcttattttt agtacttgca cataaactgc atctttctta tgcagttttg ttcggcatgt
    39421 tcagtatttt tgccagtata ttggttgcac tcgcgtttaa accgattgtg aagaacaagt
    39481 atcttctttt aagtatctat ttttattttt tgttttctcc gattagtttt acacatgaat
    39541 attccactcg aacatatcgt aatgccctcg tgattccggc tgttgagatc attatcgctt
    39601 gtttattagc tatttattac cgcaaatacg gttctagcag aaaattgctg ccatggtttt
    39661 tagggctttc tgtcgctttt cctttctttt ggttcattcg cgaagattct atctggcttc
    39721 ttccttttac tgtagtagct ttgggtatca gtttcgtcca gatcttgcta gggcaagact
    39781 tttctttcaa agaagtaaag aagttaaaaa aacgactctt tcttctctcg aaacgggaat
    39841 ggctgaaact ttcattgttt ttacttccta tagttggctt ttccatcgtc tatcaatgga
    39901 tcgaatataa aaatgagaca acatacggta ttgcaaccat caatgaccgt tccagtggag
    39961 aatttggacg tttgatgaaa caactgatcc gaatagatga tgaaacgaac ttgaataaag
    40021 aaaacagtga gatatgggtc tcacatgctg cactaaataa agcattagcc gcatctccta
    40081 cattccatac tgtttctacc cgtattgacg aattatatac gactcacgcg tggactcaag
    40141 gtggaaaagt aaaagaatta cccggagata tcatcttttg ggcattgcga gatgtggtaa
    40201 gcgaatctgg ttattaccaa aacaatgcaa aagaaaccaa tgatttttgg aaaaaagtca
    40261 accaagaatt agaagaagcc tatcacaagg gaacaatcaa aaagaaaaaa gagttctatc
    40321 tgatgggatc aggagatgga aagacgatga gtgatctgcc aatcgtattc gatttccttc
    40381 aatcaggata cgcttatgca tggcgatata aagatttcca tcaaggagga aattatagtt
    40441 tcggaacgca agaacaagtc aaacaggctc aagaattatt aaaccttccg ctaatggaga
    40501 attggatcga tagtaatgaa ccgagaacac ctaatttcca attaacaaaa tcagcaaaag
    40561 tcgcgaatgt catcataaaa atttaccaag ttctggctat tcccgtgctg attgcttcaa
    40621 tagcagggat attacttatg atactaggaa ccgtatttgc aaaagctgat cgtgcctatt
    40681 atagttcctc tttgattgtg gtcaccggat taatactgac acaattggtt tttcttttcg
    40741 gtgtctcatg gttttgttct tatgcgccag aaaaaaagga ctatttttta agtgtctaca
    40801 ctggtgcagg cgtgccatta acgcaattca tcgtagtaac aagcatgcta gttttcagta
    40861 aattaaatct gaaaaaagct ttatcttcta aataaaaaga cccttggtag ctagattttt
    40921 aacctaacta tcaagggtct ttgtgtggaa aaatcagttt ttattcgatt tcttctaccg
    40981 tttcctgcaa aagctgttca tattttttgt ttcctttata taaatcacca atcgtccatg
    41041 ccaacaggag aaggacaaga acaatgatta cataagcgat gtgatcagcc aatgctagtt
    41101 gagcggaagt ggcttgctcg ccgaagaaac tttcgatctg tcctggtaat cctcgtaagt
    41161 tcaagtaagt tagactaatc acagagaacc agccaagaag ttttacgatg aatgaatttt
    41221 taaatcggct acccatctcc gcttggctgt tggtcatcat cagtaaagga atcatcgaaa
    41281 acggcaacgc aaaagccaag aacacctggg attcattcat taagttattc aaagcggcat
    41341 gttcttcgat cgttcctttt gtacttgtaa acaaaacaca aatcaataca ggaatcacag
    41401 aaagcaatcg tgtgaccagt cttcttagcc aaatcgggat acgcatatgg atgaatcctt
    41461 ccatgatgac ttgaccggtc aacgtaccag taatagtaga gttctggcca gaagcaagaa
    41521 gtgctacagc aaataaagtg gacaagatac cagattttgc tacagcaatc aaaataccat
    41581 tgctcatagc tgatggatca gataaagctt catacagacc aaaaaaggaa ggatcttgga
    41641 cagaaccggt tttgaagaca gcgacaccca tgatcaatag cagtgcattg actagaaaag
    41701 ccattgacaa ctggatatta gaatcccaag tagaaaaacg tacagcttgt gctacatctt
    41761 cttcgttttg gtgatcgatc ttccgagttt gtgaaactgc tgaatgaaga tataagttat
    41821 gcggcatgac tgttgcacca ataatcccta aagctccagt cagcggagtt tcgccgccga
    41881 tgaccggtga gtctgagaat gtatgactgt tagggataaa gccagcaaat aaactgtgcc
    41941 aatctgggtt agacaagcca acttgataga caaaaacgaa taaaatgacg aaaattaagc
    42001 agacaaccag tgcttcgatc ttacgaaacc cgacttttgt cagtagtaag agaacgaaaa
    42061 catctaatac agtaataaag acggcaatca ccaatggaat atcaaaaagt aagtagaggg
    42121 cgattgctgc accaatgact tctgcaatat ctgttgccat aatggctaat tcagtcaaga
    42181 tccataaaat gacacctaat gtcttacttg tgcgtgctcg gattgcctgt gccaaatcca
    42241 tttggctcac gattcctaat tttgctgcca tatactgtaa aagcatagca atcagactag
    42301 acatcaaaat aactgacatc aataaatatt ggaaattttg tcctccggtg atcgaagtag
    42361 accagttacc cgggtccata tacccaactg ctactaacgc accaggtcca gagtaagcaa
    42421 gaagtgtttt aaaaaaactt ttcccctttg gtacatcaac tgttccattt acttcagcta
    42481 aagataaacc atttgtatgt tcaataagtc gatgcttatg aaattgttta ttggattgat
    42541 tattcaagaa aaaaccacct ttcctattta tctacgatta cattctacac ctcaaaaaga
    42601 aaaaattaaa gaaaaagatt cggtacgcct aatttttttt catggcgcgt cttgctagat
    42661 gacgaaagaa attttgttct cctctaaaaa aaccactatt ttttgcatga aactaaagaa
    42721 tacgcctttc ttttttcaat aaactttagt aaaataagtc attgagagca attcggaaat
    42781 agaaaggaga gatttatatg ttatcaacag gtattgtcgt acttattgct attattgctt
    42841 tgctaatcgg cgcagtaggt ggctttttcc tagcgcgtaa atatatgaaa gactatttag
    42901 aaaaaaatcc tcccgttaat gaggacatgt tgcgatcaat gatgatgtca atggggcaaa
    42961 aaccatctga gaagaaaatt cgccagatga tgcagcaaat gaagaaccaa gggaaaaaat
    43021 aggttctgac ccaacgactt tttacgggct gattttttca gtccgttttt tatttcgtaa
    43081 tttgttagac tattcagatt attcagcaaa aaagacaagc acagacaatc ctaggctctt
    43141 gataaagaca aaggaggagt aaaatgtcga tttttagaaa attaggctgg ttttttcgtc
    43201 aggaaaagaa acattattta attggggttt tctcgctatt cgcagtggcc ttggtacagt
    43261 tagttcctcc aaaagtgatt gggatcatca ttgatgagat cgccgataaa aatttatcaa
    43321 taaagatcat tttcgggtgg atcttcctat tgattatcgc tgctttttta caatatcttt
    43381 ttcgttatat ctggcggacg aatatttggg gaagtgcagc tcgattggag aaagaacttc
    43441 ggcagcagtt attcaaacat tttacagaaa tggacaatct cttttaccaa aaatatcgga
    43501 ctggggattt gatggctcac gcaacgaatg atttgaatgc gatccagaat gtagcaggag
    43561 ctggtatctt gacctttgca gattcagtga ttacgggcgg aacaacgatc attgcgatga
    43621 ttttgtttat tgattggcgc ttaacactga ttgcgctgat tcctctgcct ttgctggccg
    43681 tcacttcacg agtgctgggg tcaaaactcc atgatgcttt tcgtgattcg caagaagctt
    43741 tttctagtat caatgataag acacaagaaa gtatcactgg gatcaaagtc attaaaacat
    43801 ttggacaaga aaaagaagat ctagcggatt ttgaagaaaa gattgaagat gcaattatta
    43861 aaaacaaacg agtcaatttt ttagactcct tatttgatcc attcattacc ttgattatcg
    43921 gtctgtctta tgttgcaaca attattttag gtggaaagta tgtcttggaa ggcacgatct
    43981 cgatcgggca gatggtctca tttattagtt atatcggtat gcttgtttgg ccgatgtttg
    44041 cgattggtcg attgttcaac gtattggaaa gaggaaatgc ttcttatgat cgcgtcaatg
    44101 aacttttgca tgaaaagacg catatcgtgg aacaactggg tgcagtgcag accccggcaa
    44161 aaggcgagct gaatgtagct atttcctctt ttaattatcc gaaagaagaa tcaccagcat
    44221 tagaacaaat caagtttgcg atccaagaag gagaaacatt aggtattgtt gggaaaactg
    44281 gtgcgggaaa aacgacgatc atcaaattac tgatgcgtga atacgatgat tatcaaggga
    44341 aaatccaatt tggcggacgt tcgatcaaag aatattcatt gaatgcttta ttaggatcaa
    44401 tcggctatgt gcctcaggat cacttcttgt tttcgatgac cattcgagat aatatccgtt
    44461 tttctaatcc aaaactttca gaagaagaag tagagcatgc ggcttcttta gcatttatca
    44521 acaatgaaat caaggaatta ccaaaaggtt atgatacctt agttggagaa cgtggagtct
    44581 ctttatctgg cggacagaaa caaaggattt cgattgctcg agcattgatc aaaaatcctg
    44641 aattattaat attagatgat gcactctctg cagtagatgc caaaacagaa gaagctatct
    44701 tgcataattt aaaagaaata agaaaagaga aaacaactat cattgcagct caccgtttaa
    44761 gtagcgtgat gcatgcaaaa gaaatcattg ttgtcgatca agggaaaatc attgaacgag
    44821 gaacccatca tgagctgctt gcactaggcg gctggtatga acaaatgtgg gagaaacagc
    44881 aattagaagc gaagatagaa ggaggcgagg cctgatggat gaaaattatc aatcggaatg
    44941 gacaaaatcg attccactta aagaacagaa aaagatcatc aaacgactga tgaagttcgc
    45001 caaacctttt agaagaacgt tcatcgttgc tatcttattt gcgtttgctt tgtctgtgat
    45061 caatgtccta ttgccaagga tcatccaaac ttttatggat gatcatctgg ctaaacagtc
    45121 ggctacgaca caagttattt tgttttttgc tggtatgtac ttatttggag tcatagtaaa
    45181 aagtatcatt tggtttttcc aatggtattt gtattccatg gcctcattga agacctatca
    45241 gtatattagg gtaaaattat ttgaaaagct gcatacacta ggtatgcgtt attttgatca
    45301 gacaccggca ggatcaaccg tttctcgagt gacgaatgac acagaaacgc tatttgaatt
    45361 ttggtacgtc tttttgatgg tattgactgg gatctttgca gtcgtttctt cattccttgc
    45421 catgtttcaa atcaatggag aaattgcctt gtggactttg gtgtttttgc cgattttagg
    45481 aatcgtcatc tggtattacc agaaattcag ttctcgtatt taccgaaata tgcgggaaaa
    45541 attaagtcag ctgaacacga aattgaatga atcgatttcc ggcatgcgta ttatccagca
    45601 gtttcgccaa gaagctcgtt tagctaaaga atttgaacaa gtgaacaatg agtatttaga
    45661 cacgcgttat gcgatgatca aaacgaattc gattctgtta agtccgatca tcaattttct
    45721 atatgcattg gcgattgcgt tggtgttgac tttgtttggg atcgatgcgt tgcattctcc
    45781 cgtagaagtt ggactgatct atgcatttac gacctatgtc cagggatttt ttaatccaat
    45841 gtctcaaatg atggactttt tgagcatctt cacagatggg atggttgctg gtagtcgtat
    45901 cttgaagatt atggatacgg aagaatatgc accacaacaa aaccctggag cagatcaaat
    45961 gattacttca ggtaagattg agtttcgcaa tgtaagcttt tcttatgatg gagagcacaa
    46021 tgtattaaac aatatctctt ttgttgctaa tccgggagag accgttgcat tagtgggaca
    46081 caccggaagc ggaaaaagct cgatcatcaa cgtattgatg cggttttacg aattttatga
    46141 aggtcagata ttgattgatg atcatgacat tcgagaatat ccaatggaag agttacgtaa
    46201 gaaaatgggg ctggtcttgc aagatgcttt cttgttttat ggggatatcg caggaaatat
    46261 tcggatgatg aatccagcta tcacagacga acagatacgc catgcggctg agtttgttca
    46321 agcaaacaaa ttcatcgatg aattaccaaa aggatatcac tcaaaagtga tcgaacatgg
    46381 tgccagctat tctagtggac aacgacagct gatcactttt gcgcgaacaa tcgtgactga
    46441 tcctaaaatt ctagtattgg atgaagcaac agcaaatatc gatactgaaa cagaaggatt
    46501 gatccaagaa ggattggcaa aaatgcgtca aggacggaca acgattgcga ttgcccatcg
    46561 gctgtcaacg attcgagatg cagaattgat tttagtttta gacaaaggtc atatagtaga
    46621 acgcgggaat catgaaacac ttctagcgca aaatggtttg tatgcagata tgtacaaact
    46681 gcaaagcagt ggtatataaa agatgttgtg acagtagaat tttgacctaa gcactagagt
    46741 gaaaataaaa catagcttct catatttttc atctgtgaga gttagtgtcg tagtcaccag
    46801 atttaaaaaa agattcgaca gctagtcaga agtgcctaat agccactaag aaagcgttga
    46861 caaaagcatt tgctttcgat aatataaaga aaacgataca acttggatag tgattgcctg
    46921 atgcaagcta aacctgatga gtctcccatg gtttcatgga cggctttttg ggtttttctt
    46981 tttgttttgg atacagccct atacatcatg gaaaggagca aaacatgctg attgagaaag
    47041 tactgaataa caacgtcgta ataaccaggg atgaaagaaa tcaggaaatg atcgtgatgg
    47101 gaaaaggttt ggcattcaaa aagaaagtgg gtgacccgat ttttgactca tgcatcgaca
    47161 aaaaatttca gttgacaaat gacgggcttt cacaacagtt ccaagaattg gcacaagcga
    47221 ttcctcttga gtacttagaa atttcttgtg aaatcattga atatacaaaa gaggctctac
    47281 aagtccagtt gaatgattct gtgtatattg cattgacgga tcatttgtat acggctatcg
    47341 aacgtcacaa aatgggaata tttgtaccaa atgtattgct gtatgatatc aaacaactat
    47401 ttcctaaaga gtatgccatc gggaaaaaaa cagtgaagaa aatctcggat aaataccaca
    47461 tcaagttatc agaagatgaa gccggattta tcgcattgca tttagtcaat gcacaaggca
    47521 ttcaaagcca gcaagacaat acctacctgt ttactataac aatacaggat attctaaata
    47581 tcgtccgcta ttactataag attacatttg atgaagattc agtccatttt tttcgattcg
    47641 tcacacactt acgttttttt ctgacacgcg tcctagatgg agaaaaatca gaagtgggag
    47701 aagtttctga ggaattgttt caggttattc aaaaaaaata taaggatacg tttggttgcg
    47761 ttgagaaaat agcagacttt ttagccgaga cgttcaacta ccagatgtcc acggacgaaa
    47821 aaatgtattt aacgatccat actgcgcgtt tagtgcatga gaatcgttgt aaataaaaaa
    47881 aggaggataa attaacaaga acgtatgaaa taagggtagt gacattcagt tggctaaacc
    47941 ttccactaat aaattggagg gaatagaaat gggaaaatac caagaattag cgagaaaaat
    48001 cgtagaaaat gtcggcggga aggaaaatat caatggtttg acacattgta tcacaaggct
    48061 tcgtttcaaa ttaaaaaacg aagaaaaagc aaatgatgag atcttgaaaa atatggacgg
    48121 tattgtaacg gtaatgcgag cgggagggca gtatcaagtt gtcattggga atcatgtgcc
    48181 agtcgtgttt gaagaggtta taaaagcagg aaaccttact tttgatgagg ctgtttcaac
    48241 agaaaaaatg agaccgtttg atatgcttat tgatggaata tcgggctgtt tccagccatt
    48301 ccttgctatc ctagctgctg gcgggatgat tcgtggactg acagcattcc ttgtcttctt
    48361 aggcgcgttt gaccgcggtt ctggcacatt tgttatgttt gataatatcg gtgattctgt
    48421 attccaattt atgcctgtta ttatcggttt aacagctgcc cgtaaattta aagtaaatga
    48481 attcgtaggg atgttgcttg gcgcagcatt aatgaatcct agcttgtcgc tggaagcttt
    48541 gagtggtgca gcagaagcac cactaacgac catattttct ggcactattt ttgaagcacc
    48601 tatttatcaa acagtattcg gcattccctg gattgcgcgt aactacgctt cttctgtcat
    48661 tcccattatc tttattgtgt tgttagctag ccaaattcag aaaccaatta aaaagttagt
    48721 acctgagatg atcgcgaatt tcttcgttcc attcttcacc gttcttatta caatgccttt
    48781 aggtttttta ctcgttggac cagtattcac attcgcaact gatattttaa tggctggatt
    48841 tgaaacactt ttagcacttt cgccagttat ttatggagca atcgtaggct tcttctggca
    48901 aattctggtg atgtttggtc tccattgggc aatcgtacca atgggattga tgcaattttc
    48961 tgtgaatggt tggcaaaata ttatgacacc tgttgcagta gtgtcttttg gacaaactgc
    49021 agcacttacc gcactctact ttaagcttag aaatccaaaa gacaaagcaa ttgcaatacc
    49081 agccattgtt tctggtattg tggggattac agagccagct atttatgggt ttacattacc
    49141 acgtaaaaaa atatttattt ttacctgtgt cggtggtgcg ttagggggcg cgtatagtgg
    49201 gttaatgaat ttaacttctt ggaatcaagg tggactaggc atctttacaa ttcccaacta
    49261 tattagacca gatggtgatt taacagatgt gattaatgta ttgattggga tcgccattgc
    49321 gatggtggta tcctttacgc tgactttttt cttttggaag gatgaagcag gtgaaacaga
    49381 tgatatacag aaaaaatcag gtaaagaaat tgtaaaaaca ccgatacaag gacaaatcgc
    49441 tccactaaat gcagcaaagg atgcagcttt tgcacaagga acactaggtc gaggaatctt
    49501 gatctaccct gaaaaaggag aagtacgtgc cccttttgac ggaacagtca tgaccctgtt
    49561 cccgacgaaa caggcaattg gaatggtttc tgaaacaggg ctggaattgc tgattcatgt
    49621 cggattggat actgtgcagt tggaagggaa atattttgaa agcttagtgc agcaaggata
    49681 aagagtgaaa caaggcgatc tgttgctacg cttcgacaaa aagaaaatcg aaaaggaagg
    49741 atacagttta gaaacacctg tgatcgtcac caattacacg gattatttgg atattttgga
    49801 aaaccaaggg gagacggtcg ggccagacga tgcacttatc accgcactga cctgaacggt
    49861 taggtgaaga atggactagg cttaactatt ctttttattc cacttcttta ttttcaaaat
    49921 tgaaaggctc tttcatgatg gctgagctga tagggcgttt atcgaatttt tgaccgacag
    49981 aaattagatg gactaaattc tgttgataat tttctgcaaa aacacaacta tataacacgt
    50041 ctagaagata acaaattgat gtattgatcg taaaattacc aatttttgaa tacagtcgct
    50101 cgcgtgtcgt aagtcgcaaa gcggctgtac tcattgcaga tagcgttgaa tcaccgatac
    50161 tggtcaaagc taaaattgga acatgatttt gtttcaatat ttctgcggta cgaaggatca
    50221 cattgttttc acccgtataa gaaatcagaa tcccgcacat atcactcgtg caattgtacg
    50281 cttcatagaa tgattcacca aaagtggtga caatcgtgac atccattttg atgcgcttca
    50341 ttttcagcat gaaatcttga gaaatcaaag tattcgagtt actggcgaaa atcacgattt
    50401 tttttgcttg aagcattagt tgtttggctt tttgcagttg gtcatgatga atgagagaaa
    50461 gtgtatcatg aatcgtcatc tgttctaaag aagccatttt atttgcgatc gtcataatac
    50521 cgtctgtggt ggaaaaagga agattcgcat ctacgtcttg aaaattccct tcaagatagg
    50581 ctgtttcagc taaaaaagca ttacgaaaac tgacccagcc atcaaaaccc attttttttg
    50641 ctacacggat gagtgtagag gggtggacat aacatcgctc agcaatcgct tggatggtca
    50701 tttcgccaag tgctggagaa tcgcttaaga gaaactggat cacttcattt tctgaaggag
    50761 aaaaggagat ttctttgatt ttttcacgta ataacatgta gataccttct tcttattttt
    50821 ttacgtaaat tataactttt ttgaaaatga tttgtaaacg gatttatact atataactta
    50881 aaatagacat tttttgacaa gatatttaca aaaatccact agaaaacagt aaattttgta
    50941 aatgttactg gaaagaaaca gatttctatt gtttgttttg tttacaaaaa agataatgaa
    51001 agtgtaaaaa agtaaaggag tgagaacatg gcaaaaggaa tcaaaatcgc tacgattggt
    51061 ggaggcagca gttacacccc cgagttgatg gaaggattta tcaaaagata tgaggaatta
    51121 ccgatacgag aaatctggct cgtagatgta gaagaaggaa aagaaaagct tgagatcgtt
    51181 agtcagatgt ctcagcgtat gtgggatgct tctccgtatg aagtcaagat ctatgcaact
    51241 ctggatcggg aagaagcatt gaaagatgcg gattttgtta cgactcagtt tcgtgtcggt
    51301 caattagatg cacgaatcaa agacgagcgg atccctagtt attatgggat gattgggcaa
    51361 gaaacaaatg gtgctggcgg gatattcaaa gcttttcgta ccgttccagt cgttttggca
    51421 atcgttgagg acatgaagcg tttatgtcca aatgcttggc tgatcaattt cgcgaaccca
    51481 agtgggatgg tgacagaagc agttatcaga tatggcaaat gggataaagt gattggatta
    51541 tgcaatgtgc cagtgatggc gatgatgaca gaaccagcaa tgcttggcaa gaaaaaagaa
    51601 gagctgatct acaagtttgc cggtctaaat catttccatt ggcacaaagt agcagataat
    51661 aaaggaaatg accgcacggc agaattgatt gatcgtttat acgatgaaga gaatggatta
    51721 ccgaaaaata tctttgatat cccgtttttc aaagaacaat taaaacaaat gaacatgatc
    51781 ccttgtggct accaccgcta ttactatcgt gaagaagaaa tgctggaaca tgctttagaa
    51841 gaatatcaaa cgattggtac aagagcgcag caagtgaaag aaacagaagc agagctattt
    51901 gaattataca aagatccaga attagaccat aaacctgaac aattgcaaaa acgaggtggc
    51961 gcttattatt cagacgctgc ctgtgaaacg attgcttcaa tctatggaaa taaagaaaca
    52021 cagatcgtgg tatctacaaa gaatgatgga gctgttcctg acctgccggc agattgtgta
    52081 gtagaagtca ctgcctatgt tggcgcacaa ggagcgagaa atgtagcgtt tggttctctt
    52141 cctgctgctg aaagaggctg gttgcaagta atgaagaata tggaattgct gacgatcgaa
    52201 gcagctgtga ctggtgatta tgggacagct ttacaggcgt ttacgatcaa tccacttata
    52261 cgatcaggaa agacagcaaa acggatcatg gatgagttgt ttattgcaca ccagcagtat
    52321 ttaccgcaat tcaaggagac aatcagccga ttaaaagaag aaggaatcga agttcaagat
    52381 gaactggcaa gagaattatc aggtaataca catataatgg aggaagtata atgggattca
    52441 gaaaagattt tttatggggc ggtgctacag cagccaatca atgtgagggc ggttatgatg
    52501 aaggtggacg cggactagca aacgtagatg ttgtgccaat cggaaaagac cgttttcctg
    52561 ttatcaccgg aaagaaaaaa atgtttgaat ttgatgagga tcatttttat ccagcaaaaa
    52621 ttgcaatcga tatgtatcat cgttataaag aagatattgc tttgtttgca gaaatggggt
    52681 tcaagactta tcgaatgtcc atcgcctgga gtcgtatttt tccaatgggg gatgagaaag
    52741 agccgaatga agctggcttg aaattttatg aggatgcctt taaagaatgc caaaagcacg
    52801 gaattgagcc acttgtgacg attacgcatt ttgattgtcc aatgcatttg atcaaagaat
    52861 atggtgcgtg gcgttccaga gaactcgttg gtttttatga aaatctgtgt cgagtcatct
    52921 tcaatcgcta taaaggactt gtcaaatatt ggctgacatt caatgagatc aatatgatcc
    52981 ttcatgcacc attcatgggc gcagggctgt attttgaaaa aggagaaaat gaagaacaaa
    53041 tcaaatatca agcggcacat catgagttgg ttgcaagtgc catcgcaacg aagattgctc
    53101 atgaagtaga tccggagaac aaagtaggct gtatgctggc agcaggagca tattatccat
    53161 acacttgcaa tcctgaagat gtttgggctt ctagaaaatc agatcgagaa aattatttct
    53221 tcattgatgt ccagtcacga ggagaatatc ccgcttatgc attgaaagaa atggagcgaa
    53281 atggcattca gatcgaaatg gaaccagggg atgccgcatt gctgaaagaa catactgttg
    53341 attttatctc tttttcttat tatgcttccc gagtttcgac taccgacaac gaactcttgg
    53401 aacagactgc aggaaatatc tttgcttctg tcaaaaatcc atatctgcaa gcaagtgaat
    53461 gggggtggca aattgatcca ttaggcttga gaataacgat gaatgatatt tatgatcgtt
    53521 atcaaaaacc attgtttatt gtagaaaacg gcttaggtgc agtcgatacg ccagatgaaa
    53581 atggttatgt ggaagatgat taccgaatcg attacctggc agcgcatatc caggcgatga
    53641 aggatgcagt agaactagac ggagtcgatc tattaggcta tacgacttgg ggatgtattg
    53701 atttagtatc agctggtacc ggtgagatga agaaaaggta cggattcatt tatgtcgatc
    53761 gtgataacca aggaaatggc acattagccc gttcaaagaa aaaatcattc aactggtata
    53821 aaaaagtaat tgattcaaat ggagaaaatc tttcgaacga ttgatcaatg atttataaaa
    53881 gtctattgtt tttcagcgga tttttcgagt ataataaagc tattcgagaa acgcaagcag
    53941 aacaatagac tttttttcgc attggctgta aagtatgctt acttgattaa gtaaaggaga
    54001 atctacatat gtatgatgta atcgttattg gcgcaggtcc tgctgggatg actgctgctt
    54061 tatatgcttc acgttcaaac ttatccgtat tgatgatcga acaaggtgcc cctggcggcc
    54121 aaatgaacaa tacggcagaa atcgaaaatt atcctggatt cgattcgatc atgggccccg
    54181 atctagctta taagatgtat gaaagtgtct caagatttgg gacagaaaat gcttatggaa
    54241 tcgttcaaga tatcaaggat cacggcagcc ataaagaagt catctgtgaa gataaaagtt
    54301 acgaaggaaa aacagtcatt atcgcaacag gatgtatcca ccgtaaatta ggcgtacctg
    54361 gcgaggaaga atttgctgga cgaggcgttt cttactgtgc agtctgtgat ggtgcgtttt
    54421 tccgtaacaa acgtctagta gtcatcgggg gtggggactc agcagtagaa gaagccatct
    54481 atttgacaca atttgcttct gaagtagtga tcgtccaccg tagagatgaa ttacgtgcac
    54541 aaaagatcat ccaagaccgt gcatttgcaa atgaaaaaat ttcctttatg tgggatacag
    54601 tcgttgacga aatcgttgga aacgaaatgg tagtgacagg tgtgaaagca cgtaatgtca
    54661 aaaccggcaa tgaatttgat ttagcagcag acggagtatt catctatgtt ggactggatc
    54721 cattaactgc accttttaga gaagcaggtt tgacgaacga agctggctgg attccaacag
    54781 acaacgaaat gaaaacgaat atgccaggcg tttttgccat cggagatgtt cgtgaaaaag
    54841 atttgcgaca aatcactaca gctgttggtg acggcggtat tgctggacaa caagtgtata
    54901 aatacttgga gtctttagaa gaaacaacag cataagttta aaaagagtag aagaacgggt
    54961 tcaattgttc ttttactctt ttttttcgcg tgaaatttac tgaatctgat ttatgcgaac
    55021 acgtccaaca ccttttgata aaagaatcct ttcttgattt aagcgttttt tggtcctcat
    55081 actttcatat ctaataagtg aatgctatac ttattaagaa ccatatttca gaaagaggtg
    55141 ttattttcat gtcttgggaa caagtgtatg aacaatgggt acatgaagaa aatttagaag
    55201 aaaacttaaa aaaacaatta aatgatctgg gtgaagatcc tgaaaaactt gaagatgctt
    55261 tttatgcacc gttggaattc ggtactgcag gtatgcgggg aatcttagga cctgggatca
    55321 atcgaatgaa catctatacg gtaagacaag caacagaagg actagcacgt ttcatggata
    55381 cacaaggtga agaaacaaaa cgccgaggtg tcgctatcgc ttatgactca cgccatcagt
    55441 caccagaatt tgcaatggaa gcagccaaaa cactagcaca tcacaatatc ccgtcttatg
    55501 tattcgaaag tctgcgtcca acaccagagc tttcttttgc agttcgtcat ttgaagacgt
    55561 ttgcgggaat catggtaacc gcatctcaca acccagcggc ttacaatgga tataaagtct
    55621 acggagaaga tggcggacaa atgcctcctg cagacgcaga tgcattgacg aaatatgtcc
    55681 gtgaagtcag caatccgcta aaagtcgaag tattatctga cgaagaagct aaacatagcg
    55741 ggttgatcac gatcatcgga gaagaagtgg acgctgctta tctagaagaa atcaaagcag
    55801 tgacgattga tcgtgaattg gttgaaacaa tggggaaaga tttgaaactt gtgtacacgc
    55861 cacttcatgg aacagggaaa atgttgggcg aacgtgcgtt gaaacaagct ggattcgaac
    55921 aattcgtact agttcccgaa caagctgtgg cagatccaga tttcactacg gtcaaatcgc
    55981 caaatccaga agaacattca gcttttgaat atgctatacg acttggagaa aaagaaggag
    56041 ctgacttgct gattgcaaca gatcctgatg cagaccgttt aggcgcagcg gttcgtttgc
    56101 cagatggttc ttatgaagta ttgactggga accaaatcgg agcattgttt gctcaatata
    56161 ttttggaagc acatcaatca agaggcactt taccagaaaa cgcagcggta ttgaaatcaa
    56221 tcgtttccag cgaattgcct acagcaattg cggaacacta cggtgctacc atgttcaatg
    56281 tgttgacagg gtttaaattc attgctgaaa aaatccaaca atttgaagaa gaccattcac
    56341 atacttttat gtttggattc gaagaaagtt atggttattt agttaaacct tttgttcgcg
    56401 ataaagacgc gatccaagca ttgcttttat tagcagaagt agcagcttac tataaaaaac
    56461 aaggcaaaac gttgtatgac ggcttgcaaa cgatttttga aacctatggc tatttcgcag
    56521 aaaaaacgat ttctgtgaca atgagcggac aagaaggttc tgcgaaaatc tctgctttga
    56581 tggaaaaatt ccgtaaagaa gcaccgacag aatttgccgg agcaaaagtt attcaaacag
    56641 aagactttaa agaattgacg agaacagacc gtgaaggaaa cgtagaaaaa ctaacaacac
    56701 cgccatccga cgtattgaag tatacattgg aagaaaatgg ctggatcgct atccgccctt
    56761 caggaactga gccgaaaatc aagttttata ttggtgtaaa aggaagctct acagaagacg
    56821 cagccgaaaa agtagcctct tatgaagcga ttatcaaaaa gatgacagaa gaataaaaaa
    56881 cttgagactg atggaaaaag tggtaaactt tagaagtcag tcttttttca agttggaggt
    56941 gaatggattg ccagacacgc aaaaatcaaa agtagagaaa gtcagtcaat tattcaaaat
    57001 gttgagtgat cccactcgtc ttaaaattct gctatatctg aaagacgggg aacaaaatgt
    57061 gacagcaatc acccaagcag tggaaatgga gcagtctgct gtatcgcatc aactacgttt
    57121 attaagagaa aatcatgtcg tcaagtctca tcgcgaggga aaagcgattt tgtatagtct
    57181 tgatgattct catgtactgg atattttgaa ccagacactc aaacatgtgg aacatcaata
    57241 acgataggtg aaaatagata aacactggag tgtgacaacg aagaaatttc gttgtcacac
    57301 tccagtgttt tttaagaaaa agacaaaaat gattaatcgc ttttttctgt tgtttcagtt
    57361 ccataataac tatgatcttc taggtctaaa gcattcaaaa taagcgaagc cgtttcttca
    57421 atagataaag atgccacatt gatcactaca catcctagtt tttcataaag atcattcgca
    57481 aaatcgagtt cagctctaat tttttcgata tcggaataag cagtatcagg gtttaatccg
    57541 taagagcgca tccgttcttt acggatatta tttaaaatat ctgggttatt cgttagtccc
    57601 acgatttttt taggatcgat ttcccacagc tgtttgggaa tatgtgcttg gggaatcaaa
    57661 ggtaaattag caacttttaa atttttattt gctaaaaaca agctcaaagg cgttttggaa
    57721 gttcgggata cgcctagcaa aacgacatct gcttctaaaa aaccacgagg atctttccca
    57781 tcatcgtatt ttacagcaaa ttccattgct ttgatccgtt tgaaatagtt ctcattcaat
    57841 aaatggaggg caccaggttg ccgaattggc ttgataccag ttaaacgttc aatttctgat
    57901 atcggtggcg tcatcacatc gaaactaaat aattgatgtt cttcacaaaa agaacgtgtt
    57961 atctcgatca gttcttgatt gattaatgta tgcaggacaa gtgctttttc ttctaatgca
    58021 tcttgcaatg cctgccttaa tgttttttca tctgtcacga acgttctgcg gaataggttg
    58081 aactcaacgg taggatactg agccatagta gcttgcgcta gttttgtcgc agtttctcca
    58141 gcagagtcgg agatgacaaa aaaagtaacg atttctgtag aatcggaaga catggataaa
    58201 acctcacttg catttttttt atgtttatta taccatactc tagaatgcgt acttcgtaat
    58261 cattttgatt tggaggaata agtcatgaaa aaacagacat tgatcgaaca atcattagaa
    58321 acattgaaaa ataacggttt taaatatact aaaaaaagag aagcattgtt aacttattta
    58381 gtgaagcgta accgctacgt atctgctaaa gaagtttttg actatatgaa tcaggaattc
    58441 aaaggggtaa gttatgatac gatttaccgg aatctccatg attttgcaga gatcgattta
    58501 ctggaagaaa ccgatttaaa tggtgaaatg aagtttcgtt ttcattgctg tcagggggaa
    58561 atcggccatc accatcattt tatctgtaca gtgtgcggaa caacgaaaga aatccatatg
    58621 tgtccaatga attatttcga agaacagcta ggtggatgca cgatcgaagg gcatagattc
    58681 gagattttcg gaagatgtga aaattgtcaa taaggattta aataaaataa catttgataa
    58741 tttaaaaaaa aaagcaagat ttccttgacg gtcaaaacag cattagatat aatatttaca
    58801 ggacagtctt gttttttgag atatatttca ataacaatta cggttacttt ttaagctcgg
    58861 agggagggaa ttaacatgtc aaaaacagtc gttcgcaaaa acgaatcact tgacgatgct
    58921 cttcgtcgct tcaaacgttc cgtgtcaaaa gcgggtactt tacaagaatc tcgtaaacgt
    58981 gaattctacg aaaaaccaag tgtaagacgc aagaaaaaat ctgaagcagc tagaaaacgc
    59041 aaaaaattct agttctgtga tgaattggag ttggtagtgt gtcactacta agtagattaa
    59101 acgatgacat gaaagcagcg atgaaagcga aagataagga atctttacaa gtcatccgaa
    59161 tgatcaagtc atctatacaa aacgagcaga ttaaagaagg tcacgacttg acagaagaag
    59221 aagaactaac ggtgttgtct cgcgaaatga aacagcgacg tgattctttg catgagtttg
    59281 aagaagcagg acgtgacgat ttagctgaaa aagtaaaaag tgaaattgta atagtcgaaa
    59341 aatatatgcc ggaacaactt tccgacgaag aaattcgaca acttgttcaa gaagcaatca
    59401 ctcaaactgg tgcttcatca atgaaagaat ttggcaaagt tatgggtgca attatgccta
    59461 aagtcaaagg aaaagcagat ggaaaccaag tgaatgcgat tgtgaaagaa ctattacaat
    59521 cttaatttta tcatttaaac tgcggacagt gattgtccgc agttttttgt gttcgtaaaa
    59581 aaagaactaa aaaacagcta gaagaaagaa taagattctt tcttctagct gtttttttcc
    59641 tgtttaatat ctcttatgtt aaattgtgtt tgatttggtt attcttctgg tagttcattt
    59701 gcttcttgtt tataccctga taggcgatag gcgtaataaa agagtaagct gccagcgtaa
    59761 ccaagtaacg ttgggaccat ccagccaagt cctaatgcag caaaaggaac gtgatgatga
    59821 taaaatccta gtaagcttgc tacgacagtt tgctgactca ctaatgcagg cgaatttgcc
    59881 aacatatcca atacggctgg aacggcagaa aagaacatcg ttacttgata gacaaatgga
    59941 ctcttttgga agaattttgc tgttaaggaa agcaagatta acgcaagtga caatggatac
    60001 aaaagcatca atactggtaa agaccattgg atgatattat ccaatccggc attcgcaacg
    60061 acaaaagaga caaaagtcgt taaccgcagc catgtcatat aactgacttt agggaacagt
    60121 ttatggaaat cttgtgcaaa agaaacaacg agtcccatag cggtagtgaa gacacctaat
    60181 gtgaccatta cccctaagaa gctagcaccg aagttaccta aataaaaatt agtgatctga
    60241 gaaagtgcag ttccgccatt ttctgataaa gacatcttat tcaaactcat cgcaccgaga
    60301 aggaccagac caaaataaat catgacttct aacgcaacgc tcaggctacc agcttttgct
    60361 gttaattctg tgactttttt atctttaaaa ccaagatcac gaactgcatg gacaaaagtg
    60421 acacttaaag caagtaaagc tactgcatca accgtgttgt atccttctaa aacgccattt
    60481 gtcaaagcgt tcgtctgata agaatctgca gcagattggt ttagattccc catgggttgg
    60541 aataaagaaa cgacaaaaat gatagctaat aatgcaagaa acaaggagtt taaatacttt
    60601 ccgacatatt tgaccaaacg tgttggatgt acagtaagga aataagcaag taaaaagaaa
    60661 agagcagaga ataaaaacat acctaatgaa tcatattttt caggcaaaaa gggtttagca
    60721 gccatttcaa aagcagttgc tgctgtccgc ggtgtaccaa agaatggtcc gatcgttaaa
    60781 tgaacaagga tcaagaacaa ggcagcatac cattttccga caggtttagc taagtcatac
    60841 agaccatcac tttttgtcac tactacagct aagatagcta ataatgggaa aagagcgcct
    60901 gagatggcaa atcctacacc agcgctgatc cagtttgatc cagccatttg acctaagtgg
    60961 acaggaaaga tcagattacc tgacccgaag aacatcccga agataagtga actgaccatc
    61021 aataattgct tccatgaata agtttttgtt tcttccataa atttttcctc caataattat
    61081 cattttgagt aacaaaataa acgttgcaga aactagaaat gccactaata tcagattcca
    61141 tgaaaaccac caccttaaaa tataaaaaaa agcccttttc cacttgggaa aagggctcta
    61201 gattctagaa cggtaccacc ttttttcgct taaaaaagct tcttcattca cggacgcttt
    61261 tcgataaagt tatccgctag cctgataatg gaggcagcca caatgatcta cgttttcgac
    61321 attgactcgg aaatgatgtt cgtctattcg atttattgtc atttctcact tacatgactc
    61381 actgggaata aatcgctgaa tagcctactg ttttcctcga cgctttgctg tatatttatt
    61441 tgttgacgtt ataatacacc tgtttttttt gaaatgcaag aatatttcaa atattttgtt
    61501 ttcttttttt gaaacaagaa aaatacccag agaatacttg ctaagttaga cggaatactt
    61561 gtcctctatc ttatgcatag cttacatgat cagctttttt tattcaaacg agacctttag
    61621 agaatggaag cagctatttt ttaacgtttc ttggtactta tggttaagca actcttttag
    61681 aaccttttct tatttgctat atagtttctt ctgagtatgg taaaatagga aagaatgaat
    61741 cgaaaaaaag gggatgtcta tttttgacgg aagagtctag ttctttagag attagattga
    61801 cggctgctga tgatgtcagc atgcttttag gtgcacacga caagcatata aaactgattg
    61861 aagaaacaac agaaacaacc atccatacac gtggagaaat cattcagatc attggtgaac
    61921 aatcccagat ttccttggct gcctcagtca ttcggacatt gcaggaattg atcaaacgag
    61981 gaatccatgt aagtacacca gatgtcgtga cggcactgaa aatggggcaa aaaggcacat
    62041 tagattattt tgttgagatg tatgaggaag agatcgtcaa agaccgtaat ggaaaaccta
    62101 tacgggtaaa aaacagcggc caaaagaaat atgtcgaatc ggtagccaaa catgatatcg
    62161 tatttggcgt aggaccagcc gggacaggaa aaacttttct tgcagtagta ttagcaatcg
    62221 ctgccttgaa aaaaggtgaa gtgcaaaaaa tcattttgac gcggcctgct gtggaagcag
    62281 gggaaaatct aggctttctt cccggggatc taaaagaaaa agtagatcct tatctgcgtc
    62341 ctgtttatga tgctttatac caaatttttg gattagatca tacgaaccga ttgatggaac
    62401 gaggcgtgat cgaaattgct cctttagctt acatgcgggg gcggacattg gatgatgcat
    62461 tcgttatttt ggatgaagca cagaacacga cagttgctca gatgaaaatg ttcctgacac
    62521 gtcttggtta tcaatcaaaa atgattgtca atggagatac gagtcagatt gatctgcctc
    62581 gagggacaac aagtggtctt gttcatgcag aacgaacatt aaagcaaatc aagaaaatcg
    62641 attttgttaa ttttgaagca agtgacgttg ttcggcaccc tgtagttgcc gaaatcatca
    62701 aagcttatga aaaggcagat ctccatcaag aataagcttt gcttaggagg ataagcacat
    62761 gttgaataaa acactgcaga aactacaaga aaaacttgga aaggcagcat tgcctttcct
    62821 gctgttcttg ttttttatca ttatctgcgg cgttacattt agtagtgtca aacaaaaggc
    62881 caatgatttc agagaaggcc aagtagcaga agaaagtatc cgtgcaaaca aaacgatcga
    62941 gaacacggaa gaaaccgaac aaaaaagaaa actggcagca gaagcagtca ctccagaata
    63001 cacttaccaa aaagatcttg cagatgacca gaataatcgg atcaagcaac tatttgaatt
    63061 gatcgataag acgaatgatg ccatcaacaa atcttatgac gaaaagattg ataaggcaaa
    63121 ggaagatgaa aatatcccaa agcctactac agaagagcgg atcgccgcgt tgaagaaaaa
    63181 ttttgaaaat gtgaatgcag aaaatgttgc gttttatcaa aaactaccga acaattttta
    63241 ttcgacgata tttgaaatga ctgaaactga gatccatact gtgagggatg agagtctgaa
    63301 gctcattgac gaacagatga gcaaacaagt tcgtgaaagt gaattggaag cttttaaaca
    63361 agaagcagaa gagcaaatcc aatatttgaa tgtcacacca gcacaacaac aaatgattcg
    63421 ctacttagtg gatcaaggta tcgtagtgaa tgacgtattg aatgagaaaa agacagaaga
    63481 attgaaacaa tccgcacgag aagctgtaca accagtgatg atcttccaag gagaaatcat
    63541 tgttcgtgaa ggtaatcaaa tcgatgcttc agctatgaaa aaattggaat tactaggact
    63601 gactaatcaa acaacttcga tttttccgct aattgccatg gttttagctg ttttgcttca
    63661 aatcggcgta ctgatttata attcacttca attccaaaat gcaggagaaa gaacaaaata
    63721 cgtgcttttc tatgtgacag ctatgtcagt cagcatagtg ctgatgaaat ttttccaatt
    63781 attccaaacg gaacaagcta cttatatccc gctgttttat cccgctgctt ttgcaccact
    63841 tgttttaagc tttttcttga atcgaagagc agggatcatg gctggtattt tccaagcagt
    63901 atctgcactt ttcatttttt atgattcgat tggcacgaac tttctaacga ttatcttgat
    63961 gtcttatgtt ttctctgggc tcatggcaac gattgtcaga cgtaaacgga tctcagaaca
    64021 aggattatct gctgccatgt gggtcattat ttttcctgtg atgatggatg tcattttgat
    64081 cgtctatcaa ggaatgagct ttggtgatgc aacgacttgg ttaatgctcg tctgcgggtt
    64141 cactggtgca ctcttctcat tcttgctgac gatcggtcta cacccatata ttgaattgat
    64201 ggtcaatgat gacagtgtaa ttgtattaaa tgaactcagc aatccaaatc atcctttatt
    64261 gaaacagttg ctggaagaag cgccaggtac ttatcatcat agtatgatgg tagctaatct
    64321 aagtgctaac gctgtagcag aaatcggcgg acgttctttg ctaactcgag tagcttgcta
    64381 ttatcatgat atcggcaaga tcaaacatgc tagctttttc gttgagaact tgccttcagg
    64441 agcggaaaac ccgcacaatt tcttattgcc agaagacagt aaacatatta tctttggaca
    64501 tgtgacagat ggagccaaaa tattggaaga ttataatatg ccacaaatgg tgatcgatat
    64561 ttgcagacag catcatggaa ccacgctaat gcgttatttc tacatcaaag cgaaagaacg
    64621 caatccggaa gtaacagaag agcaattccg ttaccctgga ccaaaaccgc aaagtcgtga
    64681 agcagggatc gtcaatattg ctgacagttg tgaggctgca gtacgggcaa tggatcatcc
    64741 gacgagcgaa aaaatcgaaa gttttgtcca taatcttatc gaagagcgta tttccgatgg
    64801 tcaattagac gatagtggac tgaccttgaa agaaatccga aaagtggaaa aatcattgat
    64861 cagcggttta agtagcacct tccattctcg gatcaaatat cctaaaatga aaacagaagt
    64921 tgagaagata aaggaagaac aagaagaata gaaagaagcg atgtataatg gatattacct
    64981 ttatggatga aacaaaccaa gtctcagaag agaaaatgaa agaaatcgat gacttgctgc
    65041 aatttgcagc atcttattta aagctgccag aggaaacaga aatgtctgtt actttcatgg
    65101 acaatgcggc aatccaagta atcaatcgtg attaccgtgg aaaagatgca ccgacagacg
    65161 tcatcagttt tgctctggaa gaagaaggcg aagacgaaat cccagtgatt tttgaagatg
    65221 gagagaatcc attgcctcgt gtactaggag acatcatgat ctctattgaa cgtgctgctg
    65281 aacaagcaga agcttacggc cattcatatg atcgggaact tggcttttta gcggtacatg
    65341 gattcttgca tatcaacggg tatgaccata tgacaccaga agatgagaaa gaaatgtttg
    65401 gtttacagaa agagatcttg gatgcctatg gactcaaaag ataaaaacgt agagaaaaac
    65461 aaacatttcc tgatgtctgt ggaatttgct gtccaaggag tcaaaaccgt ttttgaggaa
    65521 gaacgcaata tgaggaaaca tgttgcgttc ggtatccttg ctttatttat gggcgtgatt
    65581 ttccagcttg atcggataga gtggttatgg ctgcttttag ctgtttttct cgtttggata
    65641 gtagagatca tcaatactgt ttttgaaaat gtagtggaca tgtttacgga ttttcatttt
    65701 catccgattg ggaaaaaaat caaagatatg gcagctggag cagttttagt gaccgcttgt
    65761 tttgctgtca tcattgggtt gattttattt gtccctaaaa tatatcattt gttgtttaat
    65821 taaaaaggag aacgtatatg ccagaacata aatcagggtt tgtcgcaatc gtcggccgcc
    65881 cgaatgtagg aaaatccaca ttattgaacc gaatcgtggg tcaaaaaatt gccattatga
    65941 gtgacaaggc acagacaact agaaataaaa tccaaggagt atatactaca ccagaagctc
    66001 agctgatttt tatcgataca ccaggaatcc ataaaccaaa gcatcgtcta ggagatttta
    66061 tggtagaagc agcttacagt gcgttgaaag aagtggatgc agtcttattt atgatcagtg
    66121 ctgatcaaaa acgcggtcgg ggagacgatt ttattattga acgtctaaaa aacgtgcatt
    66181 ctccagttta tctgattatc aataaaatcg ataagatcca tccagacgag ttgctgggaa
    66241 tcatcgaaga ttattcgacg cagatgcctt ttacacaagt gattccgatc tctgctacag
    66301 aaggaaacaa tgtcgaacgc ttaatggatg tattagtcag tgaaatgcca gagggcccac
    66361 aatattttcc agatgatcaa gtgactgatc atcctgaata cttcatcgtt tctgaattga
    66421 tccgtgagaa agtcttgttt ttaacacgag acgaagtgcc tcattctgtc gcagtcgttg
    66481 ttgattcgat gaagcgaaac gagaatgata aaatccatat ccaggccacg atcatcgtcg
    66541 aaagagatag ccaaaaagga atcattatcg gcaaaggcgg aaaaatgctg aagcaagtag
    66601 gaacgaaagc aagaaaggat atcgaaaatc ttttaggaga caaagtattt ctagaacttt
    66661 gggtcaaagt ccaaaaagac tggcgagaca aaaaagtcta tctgcaagac ttcggctacc
    66721 gaaaagatga atactgatat tctgaacttc ttataggtta agtatagaaa taaactggat
    66781 aaaaatccgc acgttgagaa aaacggcgga agatcgaaac ataaataatc tggatcggca
    66841 gaatctgctt ttccagattt attttttagg agggagaata tgagccagct tgcagaatcg
    66901 aaaggcttga ttttatctag ccgtaattac aaagaaaaag ataaattagt caaaatcttt
    66961 acggaatctt ctggcaaaat gatgttttat atcaaaggaa tccatcggca aaatcagcca
    67021 ttagctccgg ctttgctccc ctttaccgaa gcagtctata tcggtaattt tcgaagtgaa
    67081 ggtttgtcgt ttttaagcag tgtcaaagac gtccatgcgt ttcggaacat ccaagaagat
    67141 atctttttga gcggttatgg tacctatttg ctaaatctag tagatgcagc aatcgaagat
    67201 catcaatatg acccgcattt attccaattt acgcaacaag ctctgcaacg gatggatcaa
    67261 ggagatgatg cagaaatcat cacgaatatc tttgaagttc aaatactgca acgcttcgga
    67321 atcgcgccaa tttggacgca ctgtgtcgta tgcggggaaa caaaaggaaa atttgactat
    67381 tcttccaaat atggcggtgt gatatgcgag aaacactggc caatggacga acaccgttat
    67441 catgcagatc ctcgcgctgt ttatttcgtt cgaatgtttt cggctatttc ttatgataag
    67501 atcagtggaa tccacttgaa agaagaaacg aagcaggcaa tccgtgacct cattgaccag
    67561 ttgtatgatg aatatgtcgg tattcatcta aaaagcaaaa agttcattga tcaaatgaag
    67621 tcttgggcac acgtattaaa gacgccagag aaaaacatgc ctgaaaaaga gatacctgaa
    67681 aaagaagaat aaatgaaaga tacaacaaaa aaatcaaaac tatttgacaa atacagggac
    67741 ttccgtctat tattaaccgt agattaaata gattgttcac tgagaggatc tattatacaa
    67801 acaagaaaac tgcaaaatga atacgtacat tgaccaagat cagtaaaaaa cacgtggttt
    67861 agcgagttcg ggagagtgga agccggaccc aaacgatttt tgaagaggca cttgcgagta
    67921 cgataaatga agctgccgaa tctttattcg gaagtagggt ggaaccgcga aattattcgt
    67981 ccctatgtct gtaatcagac atagggactt tttgtcgttt tctttcctgt attcttattg
    68041 acagcaacgc ttaaaaattg aaaggggcaa aacagatgag taaaaaattg accgtccaag
    68101 atatgatttt aacattacaa aaattttggt catcaaacgg atgcatgctg atgcaagctt
    68161 atgatacaga aaaaggagca ggtacgatga gcccatatac attcttacgg gcaatcggac
    68221 cggaaccatg gaatgctgct tatgtagagc catcccgccg accagctgac gggcgttatg
    68281 gagaaaaccc aaaccgtttg tatcagcatc atcaatttca agtcgtaatg aaaccttcac
    68341 ctgaaaatat ccaagagctt tatttagaaa gcttgcgtct tttaggaatt gatccattag
    68401 aacacgatat tcgttttgtt gaagacaact gggagaaccc atcgatgggg tgtgccggtg
    68461 tgggttggga agtatggctt gatgggatgg agatcacaca attcacgtac ttccagcaag
    68521 tcggaggact accttgtaaa ccagttactt ctgagatcac ttatggacta gaacgtcttg
    68581 cttcatatat tcaagaagtt gaaagtgtct atgatctgga atgggctgat ggcgtgaaat
    68641 atggcgagat cttcaaacaa ccagaatatg aacattccaa atattctttt gaagtaagcg
    68701 accaagactt gctactaagt aattttgacc gttttgaaaa agaagctaaa cgctgtatcg
    68761 atgaaaatct tgttcatcca gcgtatgatt atattttgaa atgcagccat acattcaact
    68821 tattagatgc ccgaggtgca gtatccgtaa cagaacgagc aggttatctt tcccgtatcc
    68881 gcaacatggc tcgtgctgta gccaaaatct ttgtggcaga acgcgaaaaa ttaggattcc
    68941 ctttattgaa taaaaacaca gcaaatccag aaaacatgaa ggaggctgaa taagatggca
    69001 aaagacttat tacttgaaat cgggctggaa gaaatgcctg ctcatgttgt cacaccaagc
    69061 atgaaacaat tagaagaaaa aacagcaaaa tttttagatg aaaaccaatt gacttatgat
    69121 acgatcgaaa cattttccac accgcgccgt ttagcaatca aagtaacaaa tattccagaa
    69181 cgacaagcgg acagcgaaga agaagtcaaa ggaccagcca aaaaaattgc tttggacgca
    69241 gatggaaact ggacgaaagc agctgaagga tttgtccgag gacaaggtct gacgacagat
    69301 gctatcactt ttagagaatt aaaaggcgtg gaatatgtct atgtaacgaa atacactcac
    69361 ggcaaagaag caaaagaagt attgacaggt ttagcagatg tcattaaaag cctcactttc
    69421 ccagtaacga tgcattgggc agaatacgat tttgaatata tccgccctat tcactggatc
    69481 gtggcattgt tagatgacga agtaatccca ttcgaaatct tggatgtcaa aacaggcaaa
    69541 gcctctcgag gtcatcgttt cttaggcgaa gatgtaacat ttacgcatgc aaaagaatac
    69601 gaagaaaaat taaatgaaca atttgttatt gcttcaccgc aaaaaagaaa agaaatgatc
    69661 atcacacaag caaacgaatt agcagaaaaa aatcactgga tcattgatct agatgaagat
    69721 ttactagaag aagtcaacaa tctagtcgaa tatccaactg tcttttctgg cgacttcgaa
    69781 gaaaaatatc tatctgttcc tgaagaagta ctagtcactt ctatgaaaga acatcaacgt
    69841 tatttcgaag tacggaacga tcaaggtatg ttgcttcctc attttatttc tgctcgtaat
    69901 ggcgatcggg taaaattgga aaatgtggta cgaggcaatc aaaaagtatt gactgctcgt
    69961 ttagaagatg cggaattctt ttataatgaa gacaagaaag cttcaatcga ccaatacgtt
    70021 gaaaaattaa aaactgttac tttccatgaa aaaatcggta gcatctatga gaaaatgcaa
    70081 cgggtacaag tcatcgctcg catcataggc gaacaagtag gactatctga ggaagaattg
    70141 atggatctgc aacgcgctgc tgaaatctat aaatttgatc tagtaaccaa catggtagga
    70201 gaattccctg aactacaagg gatcatggga gaaaaatatg ctctgcttaa aggcgagaaa
    70261 ccagccgtag caacagcgat ccgtgaacat tacatgccta tatccagtga aggagatcta
    70321 cctgagacta cagtaggttc tgttttagcg attgctgata aattagatag tatcttttct
    70381 ttctttgcag ttgggatgat cccaagtggc tcaaacgatc catatgcttt gcgccgtcaa
    70441 gcatatggtg tcgttcgaat catcgaatcg aaaaaatggg cctttccttt gtctgttctg
    70501 caagaaacga ttagtgaagt tatcagtaaa gatacggatc gttttggcat tggcttgtca
    70561 gcgggacaac aacaggtgat cgactttatc aaaggccgtc tgcgccaatt attgacaact
    70621 aagaatattc gtcatgatgt catcgaagct gttttgaacg cagaacaaaa agatctgaca
    70681 aaagtatttg cagcagcaca attgttcaag cagcatcttg cagatgaaga cttcaaacca
    70741 tcgatggaag ctttgacacg tgtcgtgaac ttagcgaaaa aagcggagct tgaaaaacaa
    70801 tcagaagtag accctgaact gttcgaaaac gaagcggaga aagaactgca caaagcagta
    70861 gaggcaatga aaacaagctt tgctgaccaa acgatcaacg aaaattatga tcagcttgta
    70921 agccttcgcc cactgatcga aaattatttt gatcagacga tggtcatggc agaagaacca
    70981 gcagtacgta agaaccgatt aacgcaatta agtcaaattg ctgccatggc tttgtcacta
    71041 gcaagtttag atcaaatcat cacaaaataa tttctaatat gtaaataaac cagagaacag
    71101 gcacaaaata ggctat
//
LOCUS       DAZKCW010000007        69784 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000007 DAZKCW010000000
VERSION     DAZKCW010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 69784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.007"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(6..122)
                     /locus_tag="ACG84Z_000484"
     CDS             complement(6..122)
                     /locus_tag="ACG84Z_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFP9161356.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(195..1151)
                     /locus_tag="ACG84Z_000485"
     CDS             complement(195..1151)
                     /locus_tag="ACG84Z_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFP9161357.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1322..1690
                     /locus_tag="ACG84Z_000486"
     CDS             1322..1690
                     /locus_tag="ACG84Z_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFP9161358.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            1860..2291
                     /gene="mraZ"
                     /locus_tag="ACG84Z_000487"
     CDS             1860..2291
                     /gene="mraZ"
                     /locus_tag="ACG84Z_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFP9161359.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            2312..3271
                     /gene="rsmH"
                     /locus_tag="ACG84Z_000488"
     CDS             2312..3271
                     /gene="rsmH"
                     /locus_tag="ACG84Z_000488"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFP9161360.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            3276..3677
                     /gene="ftsL"
                     /locus_tag="ACG84Z_000489"
     CDS             3276..3677
                     /gene="ftsL"
                     /locus_tag="ACG84Z_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFP9161361.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRRVK"
     gene            3678..5870
                     /locus_tag="ACG84Z_000490"
     CDS             3678..5870
                     /locus_tag="ACG84Z_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFP9161362.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            5896..6858
                     /gene="mraY"
                     /locus_tag="ACG84Z_000491"
     CDS             5896..6858
                     /gene="mraY"
                     /locus_tag="ACG84Z_000491"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFP9161363.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            6872..8233
                     /gene="murD"
                     /locus_tag="ACG84Z_000492"
     CDS             6872..8233
                     /gene="murD"
                     /locus_tag="ACG84Z_000492"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFP9161364.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            8259..9347
                     /gene="murG"
                     /locus_tag="ACG84Z_000493"
     CDS             8259..9347
                     /gene="murG"
                     /locus_tag="ACG84Z_000493"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFP9161365.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            9362..10582
                     /locus_tag="ACG84Z_000494"
     CDS             9362..10582
                     /locus_tag="ACG84Z_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFP9161366.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            10738..12063
                     /gene="ftsA"
                     /locus_tag="ACG84Z_000495"
     CDS             10738..12063
                     /gene="ftsA"
                     /locus_tag="ACG84Z_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFP9161367.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            12086..13327
                     /gene="ftsZ"
                     /locus_tag="ACG84Z_000496"
     CDS             12086..13327
                     /gene="ftsZ"
                     /locus_tag="ACG84Z_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFP9161368.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            13344..14021
                     /locus_tag="ACG84Z_000497"
     CDS             13344..14021
                     /locus_tag="ACG84Z_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFP9161369.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            14035..14634
                     /locus_tag="ACG84Z_000498"
     CDS             14035..14634
                     /locus_tag="ACG84Z_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFP9161370.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            14715..14936
                     /locus_tag="ACG84Z_000499"
     CDS             14715..14936
                     /locus_tag="ACG84Z_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFP9161371.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            14985..15767
                     /locus_tag="ACG84Z_000500"
     CDS             14985..15767
                     /locus_tag="ACG84Z_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFP9161372.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            15788..16495
                     /locus_tag="ACG84Z_000501"
     CDS             15788..16495
                     /locus_tag="ACG84Z_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFP9161373.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            16757..19555
                     /gene="ileS"
                     /locus_tag="ACG84Z_000502"
     CDS             16757..19555
                     /gene="ileS"
                     /locus_tag="ACG84Z_000502"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFP9161374.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(19604..21130)
                     /gene="zwf"
                     /locus_tag="ACG84Z_000503"
     CDS             complement(19604..21130)
                     /gene="zwf"
                     /locus_tag="ACG84Z_000503"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFP9161375.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(21145..21792)
                     /locus_tag="ACG84Z_000504"
     CDS             complement(21145..21792)
                     /locus_tag="ACG84Z_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFP9161376.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(21976..22305)
                     /locus_tag="ACG84Z_000505"
     CDS             complement(21976..22305)
                     /locus_tag="ACG84Z_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFP9161377.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            22482..23210
                     /gene="sfsA"
                     /locus_tag="ACG84Z_000506"
     CDS             22482..23210
                     /gene="sfsA"
                     /locus_tag="ACG84Z_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFP9161378.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            23226..24239
                     /locus_tag="ACG84Z_000507"
     CDS             23226..24239
                     /locus_tag="ACG84Z_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9161379.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            24239..25516
                     /locus_tag="ACG84Z_000508"
     CDS             24239..25516
                     /locus_tag="ACG84Z_000508"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFP9161380.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            25579..28281
                     /locus_tag="ACG84Z_000509"
     CDS             25579..28281
                     /locus_tag="ACG84Z_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9161381.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            28433..28750
                     /locus_tag="ACG84Z_000510"
     CDS             28433..28750
                     /locus_tag="ACG84Z_000510"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9161382.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            28780..29100
                     /locus_tag="ACG84Z_000511"
     CDS             28780..29100
                     /locus_tag="ACG84Z_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFP9161383.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            29208..30668
                     /locus_tag="ACG84Z_000512"
     CDS             29208..30668
                     /locus_tag="ACG84Z_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9161384.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            30736..30957
                     /locus_tag="ACG84Z_000513"
     CDS             30736..30957
                     /locus_tag="ACG84Z_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161385.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            30988..31170
                     /locus_tag="ACG84Z_000514"
     CDS             30988..31170
                     /locus_tag="ACG84Z_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFP9161386.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            31170..31583
                     /locus_tag="ACG84Z_000515"
     CDS             31170..31583
                     /locus_tag="ACG84Z_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFP9161387.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            31706..32887
                     /locus_tag="ACG84Z_000516"
     CDS             31706..32887
                     /locus_tag="ACG84Z_000516"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9161388.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(32958..33122)
                     /locus_tag="ACG84Z_000517"
     CDS             complement(32958..33122)
                     /locus_tag="ACG84Z_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161389.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            33276..33349
                     /locus_tag="ACG84Z_000518"
     tRNA            33276..33349
                     /locus_tag="ACG84Z_000518"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33310..33312,aa:Arg,seq:cct)
     gene            complement(33418..34557)
                     /locus_tag="ACG84Z_000519"
     CDS             complement(33418..34557)
                     /locus_tag="ACG84Z_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9161390.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            34729..34863
                     /locus_tag="ACG84Z_000520"
     CDS             34729..34863
                     /locus_tag="ACG84Z_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161391.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(34856..35491)
                     /locus_tag="ACG84Z_000521"
     CDS             complement(34856..35491)
                     /locus_tag="ACG84Z_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161392.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(35604..36239)
                     /locus_tag="ACG84Z_000522"
     CDS             complement(35604..36239)
                     /locus_tag="ACG84Z_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFP9161393.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPSTEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(36273..36734)
                     /locus_tag="ACG84Z_000523"
     CDS             complement(36273..36734)
                     /locus_tag="ACG84Z_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFP9161394.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(36864..37295)
                     /locus_tag="ACG84Z_000524"
     CDS             complement(36864..37295)
                     /locus_tag="ACG84Z_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFP9161395.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(37313..37633)
                     /locus_tag="ACG84Z_000525"
     CDS             complement(37313..37633)
                     /locus_tag="ACG84Z_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9161396.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            37932..38708
                     /locus_tag="ACG84Z_000526"
     CDS             37932..38708
                     /locus_tag="ACG84Z_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFP9161397.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            38723..38926
                     /locus_tag="ACG84Z_000527"
     CDS             38723..38926
                     /locus_tag="ACG84Z_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9161398.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            38942..39280
                     /locus_tag="ACG84Z_000528"
     CDS             38942..39280
                     /locus_tag="ACG84Z_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFP9161399.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            39267..39446
                     /locus_tag="ACG84Z_000529"
     CDS             39267..39446
                     /locus_tag="ACG84Z_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161400.1"
                     /translation="MGKFNRALVFSAPLIIYALELWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(39489..39959)
                     /locus_tag="ACG84Z_000530"
     CDS             complement(39489..39959)
                     /locus_tag="ACG84Z_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161401.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            40046..40744
                     /locus_tag="ACG84Z_000531"
     CDS             40046..40744
                     /locus_tag="ACG84Z_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFP9161402.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            40922..41263
                     /locus_tag="ACG84Z_000532"
     CDS             40922..41263
                     /locus_tag="ACG84Z_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161403.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            41256..41927
                     /locus_tag="ACG84Z_000533"
     CDS             41256..41927
                     /locus_tag="ACG84Z_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFP9161404.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            41933..42619
                     /locus_tag="ACG84Z_000534"
     CDS             41933..42619
                     /locus_tag="ACG84Z_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFP9161405.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            42622..43371
                     /locus_tag="ACG84Z_000535"
     CDS             42622..43371
                     /locus_tag="ACG84Z_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9161406.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            43383..43652
                     /locus_tag="ACG84Z_000536"
     CDS             43383..43652
                     /locus_tag="ACG84Z_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161407.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            43657..43821
                     /locus_tag="ACG84Z_000537"
     CDS             43657..43821
                     /locus_tag="ACG84Z_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161408.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            43814..44116
                     /locus_tag="ACG84Z_000538"
     CDS             43814..44116
                     /locus_tag="ACG84Z_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161409.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            44113..44274
                     /locus_tag="ACG84Z_000539"
     CDS             44113..44274
                     /locus_tag="ACG84Z_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFP9161410.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            44271..44576
                     /locus_tag="ACG84Z_000540"
     CDS             44271..44576
                     /locus_tag="ACG84Z_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161411.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            44576..44932
                     /locus_tag="ACG84Z_000541"
     CDS             44576..44932
                     /locus_tag="ACG84Z_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFP9161412.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            44892..45137
                     /locus_tag="ACG84Z_000542"
     CDS             44892..45137
                     /locus_tag="ACG84Z_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161413.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            45134..45553
                     /locus_tag="ACG84Z_000543"
     CDS             45134..45553
                     /locus_tag="ACG84Z_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFP9161414.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            45550..46107
                     /locus_tag="ACG84Z_000544"
     CDS             45550..46107
                     /locus_tag="ACG84Z_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFP9161415.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            46104..46400
                     /locus_tag="ACG84Z_000545"
     CDS             46104..46400
                     /locus_tag="ACG84Z_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161416.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            46477..46890
                     /locus_tag="ACG84Z_000546"
     CDS             46477..46890
                     /locus_tag="ACG84Z_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFP9161417.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            47199..47351
                     /locus_tag="ACG84Z_000547"
     CDS             47199..47351
                     /locus_tag="ACG84Z_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161418.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(47348..47623)
                     /locus_tag="ACG84Z_000548"
     CDS             complement(47348..47623)
                     /locus_tag="ACG84Z_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161419.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            48481..48648
                     /locus_tag="ACG84Z_000549"
     CDS             48481..48648
                     /locus_tag="ACG84Z_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFP9161420.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            48674..49018
                     /locus_tag="ACG84Z_000550"
     CDS             48674..49018
                     /locus_tag="ACG84Z_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFP9161421.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            49023..49304
                     /locus_tag="ACG84Z_000551"
     CDS             49023..49304
                     /locus_tag="ACG84Z_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161422.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            49407..49721
                     /locus_tag="ACG84Z_000552"
     CDS             49407..49721
                     /locus_tag="ACG84Z_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFP9161423.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            49699..51393
                     /locus_tag="ACG84Z_000553"
     CDS             49699..51393
                     /locus_tag="ACG84Z_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFP9161424.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            51413..52591
                     /locus_tag="ACG84Z_000554"
     CDS             51413..52591
                     /locus_tag="ACG84Z_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFP9161425.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            52554..53240
                     /locus_tag="ACG84Z_000555"
     CDS             52554..53240
                     /locus_tag="ACG84Z_000555"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFP9161426.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            53240..54400
                     /locus_tag="ACG84Z_000556"
     CDS             53240..54400
                     /locus_tag="ACG84Z_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFP9161427.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            54410..55285
                     /locus_tag="ACG84Z_000557"
     CDS             54410..55285
                     /locus_tag="ACG84Z_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161428.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            55282..55593
                     /locus_tag="ACG84Z_000558"
     CDS             55282..55593
                     /locus_tag="ACG84Z_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161429.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            55583..55936
                     /locus_tag="ACG84Z_000559"
     CDS             55583..55936
                     /locus_tag="ACG84Z_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFP9161430.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            55926..56327
                     /locus_tag="ACG84Z_000560"
     CDS             55926..56327
                     /locus_tag="ACG84Z_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161431.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            56320..56724
                     /locus_tag="ACG84Z_000561"
     CDS             56320..56724
                     /locus_tag="ACG84Z_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161432.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            56736..57344
                     /locus_tag="ACG84Z_000562"
     CDS             56736..57344
                     /locus_tag="ACG84Z_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFP9161433.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            57364..57726
                     /locus_tag="ACG84Z_000563"
     CDS             57364..57726
                     /locus_tag="ACG84Z_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161434.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            57729..57911
                     /locus_tag="ACG84Z_000564"
     CDS             57729..57911
                     /locus_tag="ACG84Z_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161435.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            57928..61359
                     /locus_tag="ACG84Z_000565"
     CDS             57928..61359
                     /locus_tag="ACG84Z_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFP9161436.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGTKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            61410..62147
                     /locus_tag="ACG84Z_000566"
     CDS             61410..62147
                     /locus_tag="ACG84Z_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFP9161437.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            62157..64448
                     /locus_tag="ACG84Z_000567"
     CDS             62157..64448
                     /locus_tag="ACG84Z_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFP9161438.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFCSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            64472..66598
                     /locus_tag="ACG84Z_000568"
     CDS             64472..66598
                     /locus_tag="ACG84Z_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161439.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            66615..66764
                     /locus_tag="ACG84Z_000569"
     CDS             66615..66764
                     /locus_tag="ACG84Z_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161440.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            66761..67207
                     /locus_tag="ACG84Z_000570"
     CDS             66761..67207
                     /locus_tag="ACG84Z_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161441.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            67209..67346
                     /locus_tag="ACG84Z_000571"
     CDS             67209..67346
                     /locus_tag="ACG84Z_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFP9161442.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            67384..67677
                     /locus_tag="ACG84Z_000572"
     CDS             67384..67677
                     /locus_tag="ACG84Z_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161443.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            67674..67898
                     /locus_tag="ACG84Z_000573"
     CDS             67674..67898
                     /locus_tag="ACG84Z_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFP9161444.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            67895..68920
                     /locus_tag="ACG84Z_000574"
     CDS             67895..68920
                     /locus_tag="ACG84Z_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFP9161445.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            69110..69183
                     /locus_tag="ACG84Z_000575"
     tRNA            69110..69183
                     /locus_tag="ACG84Z_000575"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:69144..69146,aa:Ile,seq:cat)
BASE COUNT        23872 a        11309 c        14392 g        20211 t
ORIGIN      
        1 tatttttaca tgacactcat tacagcagtc aatacaacag atccaatcgt taaaatcagc
       61 attgtccaaa tgacaaattt tgttacttta gcaaaagtac ttgtttgttt tttttcacgc
      121 attgttttca acctcgtcat taattagttg attcaagtgt acaatctttt ttccatttcc
      181 acaagagggc ttttttataa aaacttccct ttttttaaat aataggtagt tacgatacaa
      241 ataaataatg ttaatagaac tagccatata aaggcatcat ccctttcagc aataggtaac
      301 ttaatgttca ttccatagat actgccgacg attgtcggta tagttaaaat aatcgttaaa
      361 gaagttaaaa ttttcataat attattcaga ttattcgata cgattgctga aaaagtctga
      421 ttcatttgtt ctactagttt taattgaatg cgagaagtag tcattgcctg ctctgtttcc
      481 accaatacat cacgtaaatg atttttcaaa gcatgatttt cttggaaaag tttattttgc
      541 gctagttctt tcaatgcatc taaattagca gaagtcgctt ctctgaaata aacgaggctt
      601 ttttggatat ccatgatttg ataaagttgt ttgttttcag tggatacttg aagtttggct
      661 tccaaagtat cgcattgaga ttgaagcgta gctaaataac tgttgtaaga gagtgtgacc
      721 tgccaaatga attgaaagaa gatattgaga ttaggcgaaa tatcactttt tggaaaggtc
      781 tggctaaaga ctttctttaa aaacagtggt tcatgattcg taattgtgat aagcttcttt
      841 ttgggcgtca aaataataga gagcgggtat gtatccactt gaaaataacc gctaggactt
      901 gttttagcaa aaggatattg taacaataat aacgctggct ttgtcaactt tgattgattg
      961 aattcttctg tacgggaatt ttctgcatcg tccaatatgg aagtgatgta atctgacgga
     1021 atttcaaatt gatgtgtcag ctgatgaatc tcttcttgat taggacgttc tacacaatac
     1081 cagatcgttt ggtcagtttc ctttccggta ttacgcagtt tctcattatc taatgtaaaa
     1141 tatttgatca tgattttcct cctgttgcct gtttctttta ttataacgga tagggaattg
     1201 gaatacatgg aatgtgtttg taagatatag aatataactg cataaattta aataaaatga
     1261 aacagttgtg taaagtatat acagtatact tgaagcaacg ataaaaaagg agtttacgtt
     1321 catgggcaca ttcacaccac ttatcttgtt ttggtatatt tacccggtaa tcgttttgtt
     1381 tggttgccaa tttcttgtaa aattattttc gttaaatcgt cgttttaaaa taaaagcccc
     1441 tgatttggcg attccttttt tgtggggcgg tatgcatgca ttgtctagaa atacagggac
     1501 aatttctatc ttaccgtttt tctttatttc tgttttgcta atgggaattt gtattgctgt
     1561 tttccaagca tattattatg aagaaattat ttatccgcgt tatttcaaga tgacttggcg
     1621 tttggttttt ctgttgacaa tcgtcttgta cgctgtcttg atcattgtga acatactttc
     1681 ttacctatga aaaaaataga aaagctgtaa aaagtctttt aaaaggcttt ttgcagcttg
     1741 atttttaaaa aaatgtttat gaataaaaaa agttgttccc ggatttccca gaaaaggtgg
     1801 tagaaagtgg gggattgtgg tagactaatt ttagttagtg gaggaatggg gggctttcaa
     1861 tgttgatggg tgaattccaa cataatattg atgcaaaagg acgtttaatc gtgccctcaa
     1921 aacttcgtga agaacttggc gaaaagtttg ttctgacacg cggattggat ggctgtcttt
     1981 tcggctatcc gatgagcgaa tgggaaaatc tggaagctaa actgaacgaa atgccgttgg
     2041 ctaaaaaaga cgcacgtact tttgtgcgat tcttctattc ggctgccact gaatgcgaac
     2101 ttgataaaca aggacgaatc aatataccca gcacgttaag aaattatgca gctttgacaa
     2161 aaggttgcgt agtcatcggt gtatctaacc gaattgaaat ttgggatgag acacgatggc
     2221 aagatttttc tgcagcagca gaagagaact ttgacgaaat tgctgaaagt atgattgatt
     2281 tcggactata agaataggaa gaggctgact aatgactgaa acatttcaac actatacagt
     2341 catgttgaaa gaaacggtag atggattgaa catcaaaccg gatggcgttt atgtagactg
     2401 tacactcggc ggtgccggac atagtgaata tttattaagc caactaagtt ctaaagggca
     2461 tctgtatgcg tttgaccaag atcaaaaagc aatcgatcac gccaagctgc gtttagcttc
     2521 ttatgtcgaa caaggtatgg tcacatttat caaagcgaac ttcagagaat tagaagaacg
     2581 cttgagtgag catgtagata aggtagacgg cattttgtat gatctagggg tttcctctcc
     2641 tcagctagat gaagcagaac gtggatttag ttatcatcaa gatgcaccgt tggatatgcg
     2701 catggatcag tcagctcctt tatccgctta tcacgtaatt aatgaatatt cctaccatga
     2761 attagtaaag attttcttcc gctatggcga ggagaaattt tccaaacaaa ttgctcgtga
     2821 aatcgaacga gtacgaaaaa caaaaccaat ccaaacaact ggtgagcttg tcgaaatcat
     2881 taaacaagtc atcccagctc ccgcaagaag aaaaggcggg catcctgcaa aaagaatttt
     2941 tcaagctgtg cggattgcag taaatgacga actcggtgcc gaagaggcct ctttagaaca
     3001 ggcaatccgg ttattgaaag tcaatggaag aatcagcgta atcacattcc attcattgga
     3061 agacagaatt gtcaaaagta tgtttaaaga atatagtacg gtacaagatc taccaccggg
     3121 acttcctgtc atacctgacg aattccaacc agaactgaaa gtcattactc gtaaaccaat
     3181 ccttccttca gaggaagagc taacagaaaa caatcgatca cgcagtgcaa agttacgtat
     3241 tgcagaaaaa ataagaatga aagaggagta gaatgatggc agaattaaag aaaatgcaag
     3301 attacgaata tgatttacct gaattggtgg atcagccgga acaacaaatg cctgattctt
     3361 cttcgaatca agaaatcatt cttccacaat caccggcaaa acgattaaag cagatttctg
     3421 ctttggaaaa aattgctgtg gcaagcgtgg cgattgctat tgttgcttta tgtgttttaa
     3481 cagttatgct gcgcacaaat atcagcggag ctgaaaaaga aatcacgtca atacaaacag
     3541 aaatcaatga taaaaagcaa gaaaaaacga gtttagaaca agaaaaaaac gaactttctc
     3601 gtactgaacg gattaaacaa atcgcagaag aaaaaggatt gtctattaat gacgacaatt
     3661 taaggagagt gaagtaaatg agtcttaaaa ataaaattcg gcggtttatg gaaaagaaaa
     3721 atctaaatcc gatgaacaat cgcaaaaaag taggtatcat tttatttgct acgagtattg
     3781 gattgttctt tttatttgcc gtccgtttct cgtatatcgt tattggaggt catgttgctg
     3841 gtacctcatt agctgaaaaa acaaaacagt tgtaccaagg aagtgaagta gtaaaagcaa
     3901 aaagaggaac gatttatgat cgtaacggtg tggcgctcgc agaagatgcc tcctcttatt
     3961 caattaaagc gatactctca aaaacatata cctctgggga taaaaaactg tatgttgaag
     4021 aaaagaattt tgataaaata gcagaaatcc tgcataagaa tctttctata gacaaaaaag
     4081 atgcactgaa tattttagag gacggcgcaa aaaaagagct gtatcaagtt gaatttggta
     4141 gctatgggaa aaatatctcc caagaaacca agcaaaacat cgaagcggac atgaaaaaag
     4201 aaggtgtcgc tggtctttat tttgtcgacc atcaggctcg gatgtatcca aatggcgtct
     4261 tttcttctca ttttattgga tacgcagttc cagacaaaga tgagaatggc ttagttggta
     4321 aactaggttt ggagtctgct tacaatgata tcttgagcgg taaagatggt aagattattt
     4381 atcaaaaaga taattttcaa aatcctctgc caggtacagt ggcagaagaa gaaaaagctg
     4441 tcgacggaca agatatctac acgactttag acagcagact acaaagttat ttagaaacac
     4501 tgatggatca agtaaatgaa gaatatcagc cagaagaatt gacagcagtc ctgatgaaag
     4561 caaaaaccgg agaaatcttg gcaatgggac aacgacctac tttcaatcct gaaacaatgg
     4621 aaggattgac tggaaaagat gctatctggc gtaatttctt ggtacaagat agttatgaac
     4681 caggatcaac catgaaagtt ttcactactg cagctgctat cgaagaagga gaattcaacg
     4741 agaatgaaac cttccaatct ggaaaaatcc aagtagaaga tgctacgatc aatgaccatg
     4801 actttggtga aaaaggtgtg ctgaccatgc gtcaagctct ttcatggtca agtaacgtcg
     4861 ggatggtcat actggaacag cgattaggcg gacgatggta taactattta caaaaactgg
     4921 gatttggaca aagtactcat tctggattag atgatgaagt aaacggtgct ttacctacat
     4981 taaatattgt cgaccgagca atgagtgctt atggacaagc ggtaggtgtg acgaatttcc
     5041 aaatgatgaa agctttcact tctattgcga ataacggtac aatgattcaa cctcgatata
     5101 tcagcaaagt ggtggatccc caaactggag aagagcgaac aactcaaaca gaagttctag
     5161 ggcaaccttt ttcaaaagaa acaacagaaa aagtccgtga atatatgaga gatgttgtcg
     5221 aaagcgaaaa ctacggtagt gcttatggtg tatatagtgt acctggatac aatgtatcgg
     5281 caaaaaccgg aacagcccaa atcgcttctg atacaggggg atatcaaaca ggagatacag
     5341 cctacctgta ttcgattgtg gagatggttc cttctgaaga tccagactat gtcttgtatc
     5401 taacaatgaa acaccctaag acatatgatc gaatggcatt ggctaaaatc gcaaatccat
     5461 tgatgaaacg ggcaatggat tttaaagaaa ctgaagaaga ttcagataca gaaacaaaaa
     5521 cagaaaaagt atccgtagcc gattatcgta atcttgaagc ggacgttgca gcagctgatg
     5581 ctcaaaaaag tggactgcaa cctgtagtga tcggtaatgg taaaaaagta caaaaacaat
     5641 ctactgccaa cggtgatcag ttgatctctg gagaaaaact gatcctatat actggtggtg
     5701 ataagctgat gcctgacgta acaggatggt caaaagcaga tatcatgaag ctggggaaaa
     5761 tcctcggtat tgaagttagt tttgatggag atggttattg tgtcaaacaa gaacttgctc
     5821 catatgaaaa aatcactgaa gacaaactta gttttacttt agaagaataa gaagagaaat
     5881 aggagagaaa agagcatgga atggacacaa gcattgattc ccattgtcag cagttgtgca
     5941 atgacaattg ccgcaatgcc gctatttatt ggttattttc aaatgaaaaa gcaaggtcag
     6001 gcgattcgtg aggagggacc aaagtggcac aatagcaaag ccggaactcc tacaatgggc
     6061 ggcttagtgt ttctgatcgg ctctattttg acaggaattt gggttggagc ttggcaaaaa
     6121 cagctaactc ctactctttt catcttgctt tttgtattag cgttatacgg agtaatcggc
     6181 tttcttgatg attttataaa aatattcaag aaaagaaaca tgggactgaa ctcgaagcag
     6241 aaattgattg gacagattct agggggaatc atcttttatc ttgtttaccg ttctgaaggt
     6301 tatccaggtg tattgaattt cttcggacta gatctacctt taggaatcat ttatggtatt
     6361 ttcgctctct tctggcttgt tggattttca aatgcagtaa atctgacaga tggcatcgat
     6421 ggattagttg ctggcttagg aagtatctct tttgcagctt acggtctaat tgcttggcat
     6481 cagcatcagt atgatgtatt aatcatttgc ttaagtgttt taggaggttt actgggtttc
     6541 ttcgtctaca acagaaaacc tgccaagatt tttatgggag atgtcggttc attagcgttg
     6601 ggcggacttt tagcggcaat ttctataatg ctaaaccaag aatggacatt gcttttgatt
     6661 ggtttgatct atgttatgga aacagcaagt gtgatgcttc aagttacttc ctttaagctt
     6721 acaggaaaac gaatttttaa aatgtctcca attcatcatc actttgaaat gtgcggatgg
     6781 tcggagtgga agattgatac agttttttgg ttgatcagca ttgtgacttc gttgatcaca
     6841 ttatggatcg tttggtagga gatgacggga aatgaaaaaa atatcaacat atgaaaataa
     6901 gaaagtgctt gtcttaggac tcgcaaaaag cggagtaagt gcggccaaat tattacatga
     6961 attgggcgca cttgtcaccg ttaatgatgg aaaacctttt gacgaaaatc cggaagcaca
     7021 agagctgctt tctttaggga taaaagtaat aacaggtagt catccaatcg aattgttgga
     7081 tgaagaattt tcattgatgg tcaaaaatcc agggattccc tacagtcatc ctttagtagc
     7141 aaaagcccaa gaaatgggta ttccggtaat tacggaagtt gagctagctt acgaagtagc
     7201 ggaatgccca attattggga ttacaggaac gaacggaaaa acaacgacaa caacgatgac
     7261 aggactacta ctgaatgcag gagcagatca aggaattgca cgtttagcgg gtaatattgg
     7321 gtatccagca agtggtgtag cgcaagaagc aaaatcagaa gataaaattg tgatggaatt
     7381 gtctagcttc caactcatgg gaatcacaga tttccgccct catatagcgg tgattaccaa
     7441 tatctatgaa gcacatattg attatcatgg tacaagaaaa gaatatgtca aagctaaatg
     7501 gaaccttcaa aaaaacatga cagaaaaaga ttatctgatc cttaactgga atcagtcaga
     7561 actacaagaa ttagcgcaaa gaacaaaagc acgcgtactg cctttctcga caaaagaagt
     7621 gttggaagac ggtgtgtatg ctgacgatta ctcaatatac tataaaaaag aaaaaataat
     7681 ggaaatatct gaacttggcg taccaggtaa gcataatgta gaaaatgcac tagctgctat
     7741 ttctgtagca aaattgtatg gtatatcaaa tgaagctata cgagaaacgt tgcatttttt
     7801 ccatggcgta ccacatcgta cgcaatatgt aggagaaatc caaggcagaa aattttataa
     7861 tgattcaaaa gcaaccaata ttttagcgac taaaatggct ctaagtggat ttgaaacgtc
     7921 taaggtcgtg ttattggctg gcggattaga cagaggaaat acatttgatg aattaattcc
     7981 ttcattaaaa ggaatcaaag caatggtcgt atttggccaa acaaaagaaa agttgatgga
     8041 tgctggaaaa aaagcaggca tcgagacaat agtaacagcc gattctgtag aacaagcagt
     8101 tcctttagca ttagaaaaca gtacagatgg tgatgtagtt ttattatcac cagcgaatgc
     8161 cagctgggat caatacccaa attttgaaac tagaggaaac agattcatgg aagctgtgaa
     8221 ccgattaaaa tagaaaaagt agaagcgagc gataaaaaat gaaaattttg gttacaggcg
     8281 gaggaacagg gggacatatt tatccagctc ttgcctttgt caattatgta aagactcaag
     8341 aaccgaatgc tgaattcatg tatgtgggag caaaacgagg tctagaaaac aaaatcgtcc
     8401 ctgatacagg aatgcctttc cataccttgg agattcaagg atttaaacga aaaatttcca
     8461 tgcataacat caagacggtc cgattgtttc ttaagagtat ccgtcaagca aaaaaaatcc
     8521 tcagtgattt tcaaccagat atcgttatcg gtactggagg atatgtttcc ggagcggtag
     8581 tgtacgctgc agccaaaatg ggtattccaa cagttatcca tgaacaaaac agtgtaccag
     8641 gtgttaccaa taaattttta agccgatatg tggatcggat cgctctttca tttaaagatg
     8701 cggcttcctt ttttcctgaa aacaaagcag ttcttgtagg taatcctcga gcacaagaag
     8761 tagcagatac taaaaaatca gatattttga aaacatttga tttggatcca gaaaagaaaa
     8821 cagtcttgat ttttggcggt agtcaaggag cacttaaaat caatcaagca gtatcagttt
     8881 ttttaagtga atatattcct tcttcttacc aagttttgta tgcttcagga gatagatatt
     8941 atgaagagat cctaaataaa ataaatcctg aaatacaaaa tattagtgtc cagccttata
     9001 tcaaaaatat ggcagaggtc atggcttcca gtgatctgct ggtggggcgt gctggtgcaa
     9061 cttcgatcgc agaattcaca gctctggggt taccggcagt gttggttccc agcccatatg
     9121 ttacgaatga tcatcagact aaaaatgcaa tgagtcttgt tcacgcagga gcagcaaaaa
     9181 tgattgcaga taatgaacta acaggtgaat cactaagtca gacagtcaac gaaatcatgg
     9241 gtgatgaaga attgcaaaag caaatgtgcc gagcttctaa agaacaagga atccctgatg
     9301 cttcaaaacg tctttatgac ttagtaaaac aaataatcaa aaaataaagg cggtggtctt
     9361 agtgagtaag aaaaaagaac caaaaaaatt gtctcatccg tcttctgatg aaaacaattt
     9421 gactccttgg caaaaggcta accgaaaata tctggcagaa caagagatga aaaaccaaga
     9481 gccaaaaaaa gaagacataa cattagatac acccctttca gattctgaag aagaaaaaac
     9541 ggttcaagag gaacagcaag aagaaagcca gtccgagaaa aaaatcgaat tttttgaaga
     9601 gatcaagcaa aagaaaaacg gtggaccata taacggttct tttttgaacc ggctgcccaa
     9661 tttaaaaagt caacggcaca aagtactatt tcgtcggtta gctttgatca tcactgtatt
     9721 gggtataccg ctgatttttt tgatctatta tgtttctcct tatagcaaat tacaagcagt
     9781 tgcagtatca ggcaataaga cagtcaacag ccaagaaatc atctctgata caaaattgtc
     9841 attaggagaa aatgtttggg gacagtattt tcatcgatct acttatatcg atcgccttaa
     9901 aaaagcacag ccaagaatcg aaacagcaaa tatacatttc aaagggatga atgaattcga
     9961 tttggatgta acagaatata aagagattgc tttgatcgca aaaaacaatc aatactaccc
    10021 agtgattgaa aatggaacag tattagatga aaaagtagca aatcctacaa aaaatctccc
    10081 tatcttggaa gagttcaaag actctgcaaa aatcaaagaa ttaacaaagc aatacaatca
    10141 gttatcatca gaattacaaa aagcaatttc tgaaatcaag tacacgccaa gagcaagcaa
    10201 taaaaatctg atccaattga atatgaatga cggcaatcaa gttattgtaa atatcaataa
    10261 tcttgcgaac caaatgaaat attattcgca agtagccaaa gatatggatg aaaaaggtgt
    10321 gatcgacatg gaagttggta tcttctcgca tccttacggt agcactcaag aaacggaaga
    10381 atcgggccaa tcggaagaaa caactgaaag tgaagaaaat gcggatcaaa caaacgaatc
    10441 aagtgaagag gcagaaacgc aaaaagcaca aacacctgga tcgtctagca caaacggatc
    10501 atctgattca aatgattcaa gtgaaacaag tcaaatagaa gataatccaa gtacaactcc
    10561 gtcaagttta aatgaaaatt gataaaacaa ctttaaaaag taagaatgta ctttctaaaa
    10621 accagtaatt tatggtagaa ttggaagcag tgaatatatc tattaataag tatattttaa
    10681 aacggacgct agttgttcgc ttgtatatgg aatagtaagt aggagggaat cccattcatg
    10741 gcaaaaacag gaatgtatgt aggccttgat attggaacga catctgttaa agttgtcgtg
    10801 gctgaatata tcgacagcca aatgaatatt attggagtag gaaacgcaaa atcagaaggg
    10861 attaaccgag gcattatcgt tgatatcgat aaaacggtcc aagcgataca acgagcagta
    10921 cgacaagcag aagaaaaagc aggtatccag atcaaaggcg taagtgtcgg tttgccagca
    10981 aacatgcttg aagtagaaaa ttgccaggga atgattgcag ttaacggaga ttcaaaggaa
    11041 atcaccgatg aagatgtcag aaatgtggct tcagctgccc ttgttcgttc aatacctcct
    11101 gaacgtcaaa tcgtgtcaat attgccacaa gattttactg tcgatgggtt cgagggaatc
    11161 aaagatcctc gtggaatgat cggcgtaaga ttagaaatgt acggtctgtt gtttacagga
    11221 cctaaaacga tcatccataa catacgtaaa tgcgtggaaa atgccggatt aatcgtcaac
    11281 gaaatggtga ttactccttt agcgctgact gaatcaattc tttctgacgg agaaaaagat
    11341 tttggtacga tcgtcattga tatgggtggc ggccaaacaa caacggctgt tatgcatgat
    11401 aagcaattga agtttaccaa tcttgaccaa gaaggtggcg aatttgtcac taaagatatc
    11461 tctattgtat taaatacgtc atttaacaat gcagaagcgt tgaaaataaa ctacggggat
    11521 gcatacccag aacggacatc accagatgaa gaatttccag tagatgtgat tggtcagtca
    11581 gaaccagtga aagtcgatga acgctacttg tcagaaatta tttcagctcg aatggaacag
    11641 attttcaaca aagcaaaaga tgcattggac caaatcgaag cattagagtt gccaggtggc
    11701 gtcgtattga caggcggagc tgctagtctt cctggtgttg tggacttggc acaagaaatc
    11761 ttcggcgtaa atgtaaaatt gtatgttcca aatcacatgg ggctgagaaa cccggtattt
    11821 acaaatgtaa taagtatcgt ggattattca gcaaacttga gtgaagtgta tcaattggca
    11881 aaaattgctg ttacgggtga aacctcagca gctcgtcaaa tggtagttga acaagaaaca
    11941 acaaacacat atgagagcta tgaagcacct gaagaaacaa tctacgatga gccggaacca
    12001 aaagagtccg gagaaaatgt aaaaaataaa atcaagggtt tctttacaaa tatttttgat
    12061 taattcatcc tgggaggaat aagatatgga attctcaatt gataataata tcaatgacgg
    12121 cgcagtaatc aaagtcatcg gagtcggtgg tggcggtgga aatgctgtaa accgaatgat
    12181 tgaagaaaac gttaaaggtg ttgaattcat tacagccaac acagacgtgc aagcattaaa
    12241 aaattcaaaa gctgaaacag ttatccaatt aggccccaaa tatactcgtg gtttaggtgc
    12301 tggttctcag ccagaagttg gacaaaaagc ggcagaagaa agtgaacaat ccttacgcga
    12361 agctttagac ggtgcagata tgattttcat cactgcagga atgggtggag gaaccggtac
    12421 aggtgctgca ccaatcgttg caggtatcgc gaaagaattg ggcgcattga ctgttggtgt
    12481 cgtgacacgt ccattcactt ttgaaggacc gaaacgtggc cgttttgctg cagaaggtat
    12541 cgctcgtttg aaagaaaatg tggatacatt attaattatc tcaaataacc gtttattaga
    12601 agttgtagat aaaaagacac cgatgcttga agctttccgt gaagcagata atgttttacg
    12661 acaaggtgta caaggtatct ctgatttgat cacagcgcca ggttacgtta accttgactt
    12721 tgctgacgtg aaaacagtga tggaaaacca aggtacagca ttgatgggga tcggtgtggc
    12781 tagtggagaa gatcgcgtag tagaagcaac gaaaaaagca atctcctctc cattgcttga
    12841 aacatctatt gatggagctg aacaagtact tcttaacatc acaggcggtt tggatatgac
    12901 attgttcgaa gcacaagatg cttcagatat cgtagcaaat gcagcaactg gcgatgtaaa
    12961 tatcattcta ggtacatcta tcaatgaaga aatgggcgat gaaatccgtg tgacggtcat
    13021 cgcaacaggt atcgatgaat caaaaaagga acgcaagtct agccgaccag ctagacaagc
    13081 acaaatgcaa tcacctgctc aaaagactgt attagatatg gatcaagcta aaccaacttc
    13141 ttcagaagaa gaaaacagtt ttggcgattg ggatatcaga cgtgaacaaa atgttcgtcc
    13201 tagagttgat gattccaatt ttgacaatat cgaaaaaaaa gaatttgata cattcaaccg
    13261 cgaagaaaca aaatctcatg gcgatgatga attaaatacg ccaccgtttt tccgtcgtaa
    13321 aaaataaagg agaggaagag cacatgattg ctgacaactt gcagaaaatc aagcaagaaa
    13381 ttcaggattc gtgtgctctt gttcatcgtg atccgaaaga agttacatta gtagctgtaa
    13441 caaaatctgt tgaatccgct caagctgaag aattggttag agctggcgtt atgaattgtg
    13501 cagaaaaccg agtagataaa ttattagaaa agaaacaaga tttatttgat tttcctgaaa
    13561 taaagtggca tttaattggt aatttacagc gcagaaaggt aaaattgatt gtaaatgaaa
    13621 ttgattactt tcatgcgttg gacagtttaa gattagcaga agaaatccag aagcggttag
    13681 agaaagaatt atcctgtttt attgaagtaa atgtttctgg tgaggaatca aaacatggaa
    13741 tttcaccaga tgagctttta ccgtttgtgg aatctttagc tgcctgcaca aaaatcaagg
    13801 ttgttgggtt gatgactatg gcgcctaaag aagcttctga tgagcaaatc cataaagtgt
    13861 ttggtacgct gaaagaattg cgtgatcttg ttcaagcaaa aggttatgcc catgcaccat
    13921 gtagtgaatt aagtatgggg atgagtcaag actttcaaat tgcgattgaa gaaggtgcaa
    13981 catttatccg tgtaggaaca gcgctattca aagacgaata aaggaggaac aaaaatgccg
    14041 cttttaaaca gaggagcaat tgctaatttt ttcggattag ctgatgagga agagtacgaa
    14101 taccaagatt atcctgaaac aacaaaaaag gctgtacagc caactaaaaa aaatacaaca
    14161 cagaatcaat caactcattc tgtatctgct gcgaatactc atgaaaaaca aaaaacggcg
    14221 acttcacgtc ctgtaacgca tgaaagtatt cagccggctg aaaagaaaaa agtaattgaa
    14281 ctacatcaat cacctacaaa aactgtagcg aaagaaagaa cagcttcaag aacctctaca
    14341 caacctaaag caaatcttgc tggaaaaatc actgtaatgg aaccaagagc ttattctgaa
    14401 gctatggcga ttgctaaacg aatcattgct ggagaagcaa ccttagtgaa ttttcattta
    14461 gtagaagaaa aacaagcgag aagaatcgtt gattttctaa caggaacagt ttatgcacta
    14521 gatggagata tcaaacgtgt tggagatgag atttttcttt gtacaccgac tgggatggag
    14581 attgacagtt caaccgctca atcttttgca gatgcgaatt tgtttgatct gtaagaggag
    14641 gaactacgat ttatactatt gcactattac ttcatttact tcaacgggca gcctatttct
    14701 atagcattat cttgatggta tatgcattgc tctcttggtt tccaggcggg tatcaatcag
    14761 ggctaggacg attattagct aagatctgcg aaccgtatat cagtttgttc gatcgtctgc
    14821 ctttgaggat tggacccttg gatttcacaa ttttaggggc aatcctgatc ttgaacttag
    14881 ccgtacaagg tttagcacag atcgttatat ggataactgt ccatttagtt tattgattga
    14941 agcaacaaaa tctttattct cagaatagat aggaggggaa aattttggat gcaaatgtat
    15001 accagcactt tcgggcagat gaacgtacat ttatcgattc ggtaggcgat tggattgaac
    15061 aggttcaagg acaatatgca ccctatctga ccgaatttct tgacccaaga caatcctata
    15121 ttttagaaac actgattcga caaagcagtg atttgcgttt catgttttat ggcggatatg
    15181 aacaggcaga aagaaaaaga tgtttgattt tccccgatta ttacgaacct gtagaggaag
    15241 attttgaaac agcattgtat gaaatccatt atcctagcaa atttgccagc ctaagtcatg
    15301 ggaaaatcct tggaacttta gtgggaacgg ggatcaaacg ctcttacttt ggcgatatca
    15361 tctcggacgg tgatcgctgg caagtattta ttgcaaatga ggtggatcat tttgttgctg
    15421 cacaagtaac aaagattgga aaggttgctg tacgcttgga accaatcaaa tacacagaaa
    15481 tgattatgcc gaaagatagc tggacacaag aaagaggaac agttagttcc atgcgactag
    15541 acagtgtgat ctctgagatt tataatattt ccagacagcg gtccaagcag ctgatcgaag
    15601 ctggtaaagt aaaagtgaac tggacagaaa atacaagacc tgattttgta cttgaactat
    15661 tagatattat ttcagtcaga ggttatggca gagtccagat ccaagaactt gaggggaaga
    15721 cgaaaaaaga aaagtacagg gtactgttcg gtgtattacg taaataaaat aaaaaggtgg
    15781 tttactcatg gctttaactc cattagatat ccaaaataag acattcccga caaaaatgcg
    15841 gggatataat caagacgaag tagatgattt cttagattta gttgttcgtg actatgagga
    15901 attgactcaa agaaatcgag aattagaaaa agcagtcaaa cattctgaag aaaaacttga
    15961 gtacttcaat gaattaaaag atgctttgaa ccaatcaatc atcgtagctc aagatacggc
    16021 tgataaagta aaaacaagtg caagcaagga atccgaagtg atcgttactt ctgcacaaaa
    16081 caaagcagat gagttagttg cgaacgctga aaaacgtgca catcaattaa caactgatgc
    16141 agaagaaaaa gcaagaaaaa tcttgacaga tgcaacagaa aaagcaagac agcttgcgac
    16201 agaaactgaa gatcttaaga aaaaaacacg agtattccat caacgtatca gcttgatgct
    16261 tgagtctcaa ttagaacaag tgaaaagtcc ggaatgggat gaaattttac aaccattctc
    16321 cagctacgtg actgacagcc atgaagtgat caaagaagtt ttagcaaaac agcttgacaa
    16381 tgaaaatgat actgatgtaa actcagacac aggagtcata gaagcaccta tgacggcatt
    16441 tgatacacag gctattgata tctcgatcgt gcctggtgaa aatgaaaacg agtagaacag
    16501 aaaagcactt tgttattctt aaagcgagcc gatgagagtg gaagttcggt aagacactgc
    16561 atggtgaaag atcctctact tgagacctgc ttttccgaaa ttagagtaag aagcagcggc
    16621 tgacctcgtt attggtcaca gagagtttgc actagataga tgcaactaaa tttgggtggt
    16681 accacggcat gttcgtccct tgcggctgaa catgcttttt tgtgtccgga aaacaaataa
    16741 aggagtgtat ggttgaatga aaatgaaaga aaccttgcaa ttaggaaaaa caaaattccc
    16801 tatgcgtggt aatttgccaa accgagaagg cgagtggcaa aaagaatggg aagaaaatcg
    16861 aatctaccaa aaaagacaag agttgaacga aggaaaacct agctttgttc ttcatgatgg
    16921 acctccatat gccaatggta atatccattt aggacattca ttgaataaaa tcagtaaaga
    16981 cattatcatt cgttcaaaat caatgtctgg ctatcgtgca ccatatgttc caggatggga
    17041 tacacatgga ttgccgattg aacaagtatt ggctaataaa ggcgtgaaac gtaaagaaat
    17101 gtccatggca gaatacttgg aaaaatgtcg tgaatatgca ctttcccaag tagataagca
    17161 acgagcagat ttcaaacgcc taggagttgc aggagattgg gaacatcctt atgttacatt
    17221 agatccttct tatgaagctg cacaagtacg cgtatttggt aaaatggctg aaaaaagcta
    17281 tatttacaaa ggattgaaac caatttactg gtctccgtca agtgagtctt ctttagcgga
    17341 agctgaaatt gaatataaag atgtaaaatc tccatctatt tttgtagctt tcaatgtcaa
    17401 agacggcaaa gatattcttg atgaagatac agcttttgtc atttggacga caacaccatg
    17461 gacattgcca gcaaaccaag gtattgctgt aaatccaaaa tttacgtatg tattggtgga
    17521 agccgatggc cgtaagtttg tcgtagcgaa agatttgcta gaaacagtcc aatcagaaat
    17581 cggttgggaa aatgtaacag ttctaaaaga atttgctgga caagaaatgg aatatatgac
    17641 tgcaagtcat ccattctatg aacgtgaatc acttgtgatt ttaggcgatc atgttacttt
    17701 agacgctggt actggattag tccatactgc tccaggacat ggggaagatg actatatcgc
    17761 tggtagcaaa tataaactat ctgtagtgtc acctgtagac tcaaaaggat tgtttacaga
    17821 agaagcacct ggatttgaag gtatctttta tgacaaagca aatcctatga tcactgatct
    17881 attaaaagaa aaaggagctt tgctgaagct agatttcttt actcatagtt atcctcacga
    17941 ttggcggacg aaaaagcctg tgatctatcg ggcaactcca caatggtttg catctatcga
    18001 taaattccgt cagaatattt tggatgaagt agaaaaagta gagtgggtta tcccatgggg
    18061 taaaacacgt ttgtataata tgatccgtga ccgcggcgat tgggtaattt cccgtcagcg
    18121 tgcatgggga gtaccacttc cgattttcta tgctgaaaat ggagaagcaa tcatcacacc
    18181 agaaacaatc gaacatgtgg caaaattatt tgctgaacat ggatcaatta tctggtttga
    18241 aaaagaagcg aaagaacttc ttcctgaagg atttacccac ccaggttctc ctaatggcga
    18301 atttacaaaa gaaaaagata tcatggatgt ctggtttgat tctggttctt ctcatgaagc
    18361 tgttttacgt cagcgaccag aattatcatt cccagcagat atgtatttag aaggatcaga
    18421 ccaatatcgt ggctggttca actcaagtat cacgactagt gtggctatca atggtgtagc
    18481 accatacaaa tcagttattt ctcaaggatt tgctttagat ggtgaaggcc gtaagatgag
    18541 taaatcttta ggaaacatca ttgcaccaga aaaagtgatc aaacaatttg gtgcagatat
    18601 ccttcgctta tgggtatcta gtgtagatta tgaagcagat gttcgtgttt ctatggatat
    18661 cttaagtcaa gtggcagaag tatatcgtaa aatcagaaat acgatgcgtt tcttattagc
    18721 gaatacagaa gatttcgatc ctaaaaaaga tactgtttcg tacaatgatt tacgttctgt
    18781 agacaaatat atgaccgttc gattgaacca agtaatcaaa gaaatccgag aagaagggta
    18841 cgacaaatat aacttcatgc atatttaccg tacagttatg aacttcttga cggttgatct
    18901 atcgtcattc tacctggatt ttgctaaaga tgtagtttat attgaagcag aagatgatta
    18961 tcaacgtcgt tgcatgcaaa ctgttttcta tcaaacagct gtagctttga caaaattatt
    19021 gactcctatc attccgcata cagcagaaga aatctggtca ttcctgaaag aagaagagga
    19081 gtacgttcag ttaagcgagt ttcctggtta tgaagagttt gcaaaccaag aagaattgat
    19141 ggatacctgg actgctttca tggacttccg tgataatgtc ttaaaagcat tggaagaagc
    19201 aagaaacagc aaattgattg gtaaatcttt ggaagcaaaa ctaactgttt atccaaaaca
    19261 acaagttcgt gaaatgttaa aagctttgga tgcagatatt gcacaattat tgatcgtttc
    19321 accagactac tttgaagtta tggcagcaga tgaacaagtg ccagataacg ctatggtatt
    19381 tgatgatgtt gctattacag tggaaaaagc agacggggaa acttgcgatc gctgtcgcca
    19441 agttcgtaaa gatgtaggag tagatgaaaa acttcctcat ctatgcggtc gttgtgcaaa
    19501 aatcgttgaa gacttctatc ctgaagctgt agctgaagga ttcgaagaaa agtaaaaggg
    19561 aaaagggggt gtgacatgtt ctttgtcaca cccccttttg ttatcaatcg tttaattttc
    19621 cacgttcacg ataccagtta tctggttgcc agatccattc gaatccgtct ttttcaagta
    19681 gttcgaaagc tgctttaggt cccattgatc cagctttgta gttgggaaaa tccggttgtg
    19741 tttggtccca agcttttcga atgacatcca cgatatgcca agattgagcg acttcttccc
    19801 aatgagagaa gttcgttcca tcaccattca acgcatctaa tagtaatttt tcgtaagctt
    19861 ctgggctatt ttcaaccatt tctgcactat ttctaaattc caatttgatt ggttccgttt
    19921 caaatccttg ccctacttct ttcccattca aggataaaga aaatccttca gttggctgaa
    19981 tatagatcgt tagaacatta ggtggaagtg tcgtatcgtc acatggttca tcgacagatg
    20041 ttttgaatac attaacagga acttgtttga atacgatgtt gatccgagtc cctttttcag
    20101 tcaaacgttt gcctgtacgt acatagaaag gaacacctga ccaacggaag ttatcgatag
    20161 tgaatttgcc tgcgacgaat gtttcagtct ctgattgagc atccactttg tcttcttcgc
    20221 gatagccctt gaattgtaca ccatccaatt caccttgagc atattgcccg cgaacgaagt
    20281 tttctaacac ttcttcttcg ttataaatgc ggatagcttt caatgctttg atcttttctg
    20341 tacggatttc tttttcggaa aatgctactg gcggttccat tgcaagtaat gctacaacct
    20401 gtaaaatatg attttgcacc atgtctttaa gtgcgccact atgatcgtag tagcccccgc
    20461 gatcttctac accgaggttt tcgccaaaag taatttggat attgtcgata tagcgattgt
    20521 tccattgagc ctcaaaaata ttattggcaa aacggatagc tgagatgttt tggatcattt
    20581 cttttcctaa ataatgatca atcctgaaaa tatcttgttc tgggaatact tctctgattt
    20641 gctggttcaa ttcaaaagca gactggtaat cagaaccgaa cggtttttct atgatcaaac
    20701 gattgaagcc attttttgtc ataatatttt gtgatttcaa atgagaaacg atcgttccaa
    20761 aaaattgagg tgccatagcc aaataataga cacggttacc gtttaattga tagtgtccat
    20821 ctaatcggtc agacaattct tttaatgtct gataatgcgt tgaatcattt acatcatggg
    20881 attgatagta aaaatggctt gcaaaggtag ttgcttcttc atctgaagga ttcaatgcac
    20941 ggattgtttc tttgacaact tcacggtagt gctcatcgct ccagggacgg cgagcggttc
    21001 cgattacagc aaaatgctcg cctaaatttc cttttctgta aaggcggaac aaagacgggt
    21061 acaatttacg ctgggctagg tcacctgtac cgccgaatat cgtaaacaat acattttttt
    21121 cattagacat gtggatacac tcctttatat tttatcgaca aaaatcgtgc tggccgcctt
    21181 aaagctgacg gggattttct ttctatcatt ttggatagtg atcggtcctt cataagctgc
    21241 gatgtcaacg atctcatatt cttcgttgat attcaggtca atagtgacta agtaatccaa
    21301 caattctttt tcatcaagca ctcgtgcgat acgcactttt gtaccgacag gataggactc
    21361 caatgtttgt cggcgttctt catggacaac ttcctctttt ttaggaatcg atcctccatg
    21421 aggacaatgt tcaggatgat tcaaatagtt ttctaaatga tctgcaagat gttccgaagt
    21481 cacatgttcc aatacttcag catcatcatg gacttcattc cagctatagt ctaaatgttc
    21541 aactaaaaaa acttcccata agcgatgttt gcgaatcaga ctgctagctt tttgcagtcc
    21601 gcttgcagtc aattgtacac cttgataagg ggaatgttct acaagctctt ctttcacaag
    21661 tttagaaatc atttcactga cagatgcagc tgagacatct agactagata cgatttgttt
    21721 attgttgact ttcgttgtat ctccacctag ttctaaaatg attttcaaat aatcttctcg
    21781 atttggtgtc atattcgatc atcctttcat ggtaaaaaac catcattagt aagtgtaaca
    21841 aaaaaaacgt taattgacta tttttctaaa taaaaaacaa aggattttta gacgttttta
    21901 caacaaaaaa cgaaagatga tagagaagac tcattctttc gtttataaag gatatatata
    21961 tacattggga gggatctatt tttcagataa caacttatat gaagtgtctg cagattcgtc
    22021 ataaagagtt tgttcgggat aagaaaagat aagataaaaa ccatactgat cacgtacgac
    22081 taaacgatat tcatctattt ctaccacaga tgtgccaaga gactgaccgt tgatcaaaaa
    22141 cgtgtaatca gatgtaatct gtaattgttg tttttgctgg ctatcactaa agaaccatgt
    22201 accttgatac tttgagagtc cttctgactt ttccgcttgt tttttctttt tcaagtaaat
    22261 aaaacttgag agaacggtaa tgagtgaacc aagaaaatag atcatttttt ttatcaccaa
    22321 atcactcctt tatgagaaaa taatcgcata gacatattct ttcttcttta tttcattgta
    22381 ccgaataaaa gctaaaattt ctctaagact ttcgactggt ttttttactg tttttctaca
    22441 aattatgata ggatacatag taggaagaaa ggtgacataa tttgaagtat cagcaagtgg
    22501 aaatagcttt ttttattgac cgcccgaatc ggtttatagc acattgtatg aaaaaagacg
    22561 gagaaataat tattgcgcat gtcaaaaata caggtagagg aaaagaggtc ctgataccag
    22621 gcgctgaagt ggctattgta tttgctcctg gacctaaacg gaaaaccgcc tatgatctga
    22681 ttgctgtaaa aaagaagggt gactggttta atatcgatag tcaattgcct aatcggctgg
    22741 caattgatgg tattttagac ggcacgatcc ttttaccagg attaactggt ccatttacgg
    22801 tatacaagcg tgaagtaact tatcttcact ccaaatttga tatttattta gagacggtgg
    22861 tcggacaaaa agcatttgtt gaagtcaaag gtatgacact tgaaaataaa gcgattggtg
    22921 cttttcctga tgcgcccaca ctcagaggat tgaaacatat aggagaatta acgtatgccg
    22981 cacaagatgg ttatgccgct tatgtcttgt ttattgctca gttcgaacat cttcatctgg
    23041 caacgatcca tgaagaaatg caaccagcac tagctgatat ggttcgacat gcgcagcaaa
    23101 gcggagttca aatcctcgcc tataattgtc aagtatcggc agatgaggta actgtcaagc
    23161 aggccattcc atttgatgta gatatccctt ttgaagatcc tatacaatag aaagaaggta
    23221 aaataatgat caacttaggt attatcggaa caaattggat tactcatcaa tttgtccaag
    23281 cagctttaag cacaaaaaaa tatgaattga cagcggtata ttctagacat ttggaaaaag
    23341 cacaggaatt tggttctcat tatgaagggg atatcgaatt cgcaacagat ttgaagactt
    23401 ttttcaatat tactcatatg gacaccattt atattgcttc tccgaatagt cttcacttta
    23461 gtcaagctaa gcaagcaatt ttggcaggaa aaaatgtgat agttgaaaag ccagcttttt
    23521 cgacgccaaa agaaatggat gaaatcatcc atttggcaaa tgaacacaat gtgtattttt
    23581 ttgaagcagc aagaaatatc catgaatcag gttttaaaaa gattgccgat tacttaccat
    23641 taaaagacga gataatcggt gcaaatttca gctatatgaa atattcttcg cgctatgacc
    23701 aagtattaga tggagaagaa ccgaatatct tctcgactca tttctcaggt ggtgcattga
    23761 tggatttagg tgtttacctt gtatatgcag ctgttgcttg gtttggaatg ccaaaagaag
    23821 tccattattt cccaagaaag atttctactg gtgtagatgg tcttggatgg gggatcttac
    23881 gttatgagaa ttttgatgta tcgatccagc caggtaaaat cggtgattct tatttaccgt
    23941 cagagattta ttttgactca ggaacgctag tgatgaatgg agtcaatgca attgaacaag
    24001 cacaatttca tgatcgcgcg cataaagaaa tcattgattt ggcggtaaca gctgcagaaa
    24061 atccaatggc agatgaagca gaggattttg ccaatgtcat ggctcatccg aaagatccag
    24121 cttggggatt gttgtatgaa gagtggatcg agctagctag aaatgtgaac caagtgattt
    24181 atgatttaag aaaaaatggc ggcatcaaat tcgatgcaga taatgaggaa gatttttaat
    24241 gaacgaattt gtacaagtat ttcccgaaaa ttggcagaaa aaatatgagg ataaagggtt
    24301 tatctcacct tctcttattc aacgagcagt ttttcagcca ctaagtaata aacaaagtat
    24361 agtagcggtt tctcctacag gttcaggtaa aacactggct tatctttggc ctctactact
    24421 aaacgtggaa ccaggtgaag caagtgcgtt ggtcattttt gcttcttctc aagaactagc
    24481 tattcaagta gcagatgttg cacgtgaatg gggaaaagac aaagagttga aagtccaatc
    24541 tttggtgggc ggagccaacg tcaaacgtca gattgagggt ttgaaggaaa aaccagaaat
    24601 cttgattggt acaccaggaa gaatattgga attgatgaaa gcaaaaaaaa taaaagcaca
    24661 tcaagtgaaa acaatggtat ttgatgaagc agaccagcta tttgacgctg ggaacagcca
    24721 aatcattgat caaattcttc atcaagctcc aacagagtat cagctagctt ttttttcagc
    24781 gacagcagat cgttcccttg aaagcattga aaaaatcact gggaaaacgt ttgagacaat
    24841 tgacgtgaca gcagaggacg attctcgaaa aggactgaga cattactttt tacgtgtacc
    24901 gatacgaaag aaagatgact acttgagacg tctcacgcat atagaagatt ttcatggtct
    24961 gattttcttt aatcaactga ctgaattagg cgtaatggaa gaaaaattgc tgtatagagg
    25021 tgtaccggta ggaagtctgg cctctgatca gaacaagcta ctccgaaaag cagcgctaga
    25081 acaattcaaa aagaaaatgg tcagagcact tttgaccaca gatgtggcgg ctagaggttt
    25141 agatattaca ggtcttcctt atgtagtgaa tgcagaagtt ccgttaagtg aagaagctta
    25201 tttgcatcgt tcgggaagaa ctggtcgaat gggtaatgaa ggaatagtaa ttacactcgt
    25261 acaagataat aatctaagag atttaaaacg gcttttacgt ccatcaaata taacacttga
    25321 agagattttt ttatacggag gtaagctgca aactgagcag ccaaccaaag aagatgcagc
    25381 tcctgcagta aataaaaagt atgcgaaaac tttttctgga aaggagcaga acccagaata
    25441 taacaaagaa aaaataagaa aaaaagttaa aaataaatca aaaaaagaga gaaataaagg
    25501 agcaaggcgc aaataagcgc ctttttatgc tatgattatg aaaacgggaa caaaattggt
    25561 tgccagagga ggggttatgt gaaagaacgt caagaagaga tcttgcagct attgacagaa
    25621 aaccaacaag gattgacagc aagtgatgta gctgagcgct taactatcga tcgaagcaat
    25681 gcaagccgat atttaagtga actatacaag gcccatcata ttgtaaaaac cgctggccga
    25741 ccagtcgttt actctttgcc aacggaaaag tcaaaatctg atgaagtgca tgtcgactct
    25801 tctacgcaag tgacttttga aacactcgtt ggagaaaatg attctttaaa agtcagcata
    25861 cagcaggcaa aagctgcgat tctttatcca ccgcgggggt tgcatacgat tatttttgga
    25921 gaaactggta cagggaagtc gatgtttgct gaatgtatgt atcattttgc aatcgattca
    25981 gagatgcttt ctgcagatgc gccatttgtt tctttcaatt gtgcggatta tgctcaaaat
    26041 ccgcaactgc tctttggaca catctttggg atcaaaaaag gggcttacac aggagcagct
    26101 caagatagtc ccggtctaat agccaaagca gacggcggta tattgttttt agatgagatc
    26161 caccgtttac cgccggaagg gcaggaaatg ctgtttactt tcattgataa aggtatttac
    26221 cgtccgcttg gagaaagtgc acaagtacat gaagcatctg ttcagatcat tggggcgacg
    26281 actgaatctt cagaaagttt cttatctacg ttcaatcgac ggattcctat ggcaatcacc
    26341 ttgccgaatc ttgcttcacg ttcactggat gagcgttatg aaatcatctc tctttttatc
    26401 aaacaagaag cgaatcgttt gaatcaacgt atcgatatcg aaaaagaagc gattcttgcc
    26461 ttcatgcttt atgatgcgga aggaaatatc ggtcaagtga aacgagactt gaaactagtc
    26521 tgtgcaaaat cttttttaca ttaccgtact catcatgaga aaaagctaat cattcgaaaa
    26581 gaagaacttt cccttcaagt acaaaaagga ttactgaaaa tcaaggaaat accggaacgt
    26641 ctcgaccgat tcatggacag caaaagtcag tatttgacat ttgaaccagg atttgctgat
    26701 gttgtctggt cacaagatcc agaacgaaac atgcaggtct ataacgatat tgaggaaaaa
    26761 gtcacttctc tttccgaaac cggtgtggag aacattgatc tagagaccct catttcaaaa
    26821 gatgtggatg cttatttcca gacatatgtc aaagaattga ctaaaagttc gattcccaaa
    26881 gatcttttgc cagatgaaat ctggcggtta accaatcaat tgtatgatgt ggctgaaaaa
    26941 cggttagacc gtatttataa tgaaaaagct cgttttgctt ttgctttgca tctgcaaagt
    27001 acattggatc gtgtgagaga aggtcatatg atcgtccacc cagatttgaa taacgtacgg
    27061 aaaaatttta agagggaatt ccaggtagca atcgatcttt caacgatcat tgaagaagaa
    27121 gaacaagttg agattccttt tgatgaaatc ggctttatta gtatgtttct ttctatcaat
    27181 ctaggagaaa gtgagcctgt taaagaaaac aaagtagatg ttctcatatt gatgcacggc
    27241 agacagactg cttcaagcat gttggagatg gcacaagaac tattaggaac aaaagtaggg
    27301 aaagctttta atatgccact ggttatggaa gttcaaacaa tgtatgaaga agtgttacaa
    27361 tatgtcaaaa actatcaaga gcatttgacg aatggcctac tcttgttaac agatatggga
    27421 tcattaaaca ccttcagtga tttgatttat gaagagactg gcattcggac gaaagctatc
    27481 acgatgacaa gtaccatgat tgtgatagaa gcgatacgga tggcaagtgt tggaagaagc
    27541 ttagaagata tttatcaaaa tatccagctt tcctttgaat cgatcgtacg tgatcagttc
    27601 aaagcggaaa agtctgaaac tttacagcgt aaaaaagccg taatcgtgac atgctttact
    27661 ggtgaaggag tagctgccaa attatatcag cgtattatgc cagtgattaa tcaaaataag
    27721 gtagaactga tccagatgca gtttttagaa cgtgaatcat tcaaaaaaca catcgatgcc
    27781 ttattggaag aatatgagat caaagcaatt gcgggaacag ttgatgttga ttatcaaaat
    27841 atcccatttt tttcagccta tgacgttttt gatgatgaaa aactaaatat tttaaagcgt
    27901 atagctgatg atgagatccc gacagctaaa attgtcgatt cacttgctgg atcattaagc
    27961 gatgtctttt ctattgatga actgatccgt tcattgcaaa agacagttca gcagatccag
    28021 accgatttgt cgattatcgt ggaacctgga gtagatactg gaatcgttat ccatttagcc
    28081 ttcatgttag acggattgat caaacaagaa agccatcggc aatttgagaa actgtctatt
    28141 ttctcaaaaa tttatcgttt ggaaatggat atcgttcggg caaacttgat ggcactagaa
    28201 cgaaaatatc aggtaaaaat tccagaagat gatatcgcat ttcttacaca aatgtttctt
    28261 gaaaataaaa taaaaaaatg aacacactaa tcatactgtt tacacactaa acatctgtgt
    28321 gcgcactata aaaaagagct aaaaagcatg aaaacgctat ttcagctctt ttttttattg
    28381 gcatgcttct tgcgttatat aaaagtgtaa aaaaataaaa ggagtgttaa aaatggcaaa
    28441 aaaaacaatc atgttagttt gttcagcagg gatgagtacg agtttattgg tcacaaaaat
    28501 gcaaaaagca gcagaagaaa aagggatgga agccgatatt tttgcggtct ctgcctcaga
    28561 tgcagataat aatttagaat ctaagaatgt cgatgtatta ttattaggtc ctcaagtacg
    28621 tttcatgaaa gctcaatttg aacaaaaact tgcgcctaaa ggtattccat tagatgtcat
    28681 caatatgcaa gactatggca tgatgaacgg agaaaaagtt cttgcacaag cagaaaatct
    28741 aatgaaataa atcaagtatg cagttggggg tataacaacg tggaagatca acaaaatcta
    28801 gaagccatca tggggttaat catgtttggc ggtaatgcaa agagcgatgc aatggaagcg
    28861 attgcggctg ctaaaatcgg tgattttgag ttagcggata ggaaaatcgc tgatgcagaa
    28921 gaatcactta tacaagcgca tcatgcacaa acagacatgt tgacacaaga agcacaagga
    28981 aatcatatgc aagtgacatt attgactgtt cacagtcaag atcacttaat gacatctatt
    29041 gcgtttactg atttagcaaa agaaatcatc gaactttatc gtcgcgtata cagcgaataa
    29101 atacaacttc ttttttgaac ggaagaagaa aaatttttga acggattttt tattttgtta
    29161 taaggagaac tctctttata taaaaaactt ataggaggaa gtaaaaaatg aacggactat
    29221 caagttggat ggagaaatac atcctgccgg ttgccgcaaa aatcggagcg caaaaacatt
    29281 tagttgcttt gcgtgatgct tttatcggca cactgcccgc aacaatggcg ggatcagtcg
    29341 ctgtaatgat caatgcaatt attcgtgatt taccgcaaca gtttaacagt acctatgctg
    29401 acagtttagc agcagacaaa ggaatctttg ccgtattgaa tgtcatcatc ggaatcaatg
    29461 gttttgtctg gaacggtaca ctagcaatcg ccggattgat ctttgccttt tcttgggggt
    29521 ataatcttgc ccgagcttat ggagtaaatg atctagctgg ggggatcgtt ggtttagcta
    29581 ccttgattca aggtatttcc tttggtccag cattatcagc agcattagat gtgaatgttc
    29641 cttcaaatgt cgcagatgca atcaatagtt ctgagattgg tgcaacgatt gcagatggca
    29701 cactgtcagt tggattatgg ggttggctaa aactagatca tttgaatgga aacgcttatt
    29761 ttacagttat gatcatggga gctatttcag tcattatttt ttgtaaattg atgcttgcca
    29821 acattacgat caaaatgcct gattcagtac caccagcagt atctaaagca tttgcagcca
    29881 ttttaccagc gacgatcgct ttatacgtca ttgctattat caattatatc gtaggtcgtg
    29941 tagctgatgg gcaactgatc attgatttgg tgcaaaaata tattgcagaa ccattcctag
    30001 gattatctca agggttggga gcagtattga tcgtcacagt atttgttcaa gtattctggt
    30061 tctttggtat tcatggacca aatgtattgg caccagtgct agagggaatc tggggacaag
    30121 cacaactaat caatattgat attttccaaa aaggttataa cggaaaaact ggtacaccag
    30181 ccgtgttaga tgcaatcgaa gatggaaaag cttatatgtg ggtccgcgga tcgttcgatg
    30241 cttttgcatg gtttggcgga tcaggcggaa cgatcgtctt actgatagct atcttgattt
    30301 tctctaaacg tgcagattat ctaacagtag ctaaattatc cattgggcct ggtatcttca
    30361 atatcaacga accagtgatg tttggtctgc caatcgtatt gaatgcaatc atgtttatcc
    30421 cattcttgat tgctccagta gtagcaacag caattggatg gacagctact tatcttggcc
    30481 tagtcgctcc ggtatcgcag caagtcacat gggtagtacc gccgttctta ttgtcattct
    30541 tagcaacagg agcggattgg cgggcaccga tcgtaacatt agtatgtatg gtcgtgactt
    30601 tcttgatttg ggcaccattt gtcatctctg caaacaaaat ggaccctgcc gcaggcgaac
    30661 aacaataaga tgaacgtgag gagcgggacg ctttaagttt cgttcctcat aatgaatttt
    30721 cgaggaggaa ctgaaatgat tacaattgcc agtgcaatgc aacaagatga aatcaaagaa
    30781 ttgttagaag gatacaatga agaaggaatg acttttacat ttaaagaaaa acaaggaatc
    30841 aagctgttct ttgaaacaag tgcagaagat ccggaagttg cggctaaaaa agcaaaggaa
    30901 ctaatcaaag cacagccttg gggaacagtc ctttattttc aatcaacagc tgtttagaaa
    30961 atggtttaaa aagataggat ggttgagatg ataaaaaacg gtttattttt atgtagtatt
    31021 ggttctttga tcgtgttgta tagtttgaat ccacattcgc aaaggtatga tttgtatagt
    31081 atggtcacag gtctttttct aacaggatta ggaatctatt tcttcatgaa ggggaaaaaa
    31141 agagaagaag caaaggagaa aaataactaa tggaaatcac gaaaaaatta aatattccag
    31201 catcgttttt ttacgataaa gttatggact ctgtcctttt cgatgtacgt aaagcgaccg
    31261 gcaaatcagt aactagaaaa cagctgaaaa atttggagta cgtcaaacaa ttctcgcaaa
    31321 ataaccgggc tcgcataaaa atcgaagaag tcattgaaaa ccagtcttat aagtttcgta
    31381 catcgacaac gaagaatgaa ttcgtcgttc attatcaaat caaaccattg gacgattcga
    31441 cctgtgaggt tcattacaca gaaaaaatgg agtcttatgg catgcttcaa aagttgaatg
    31501 atatgctttt aggaacaatc ttgatgtatt ttaaacggag acgtttcaaa aaaatgctag
    31561 atatgatcga agcaacgtat taaatcaatg aaacatggta ctatttagtt attgaaaaat
    31621 gaagtaagct agaaggaatt tttcatagga agatagatct ttcctgcgaa tcctcactag
    31681 cttttttgta ggaaggggca gcaaaatgac aaacaaagta agagagctag gtgtatcttc
    31741 gattgaggaa atgtttgatt tagccactta tgcatttaat ggggcagata cacctgaaag
    31801 gcgagaacgt tttcgtacac ttgcggagaa ttcttggaat tacggatttt ttgatgagga
    31861 ggatcggcta acaagtcaag tcatggcgac cccttttcca gtgaattttt acggacaaga
    31921 gtacctaatg gccggcattg gctatgttgc ttcttatcca gaagcaaggg gacaaggcgg
    31981 gatcaatcag atcatggaaa agatccttga agattgccgt gatcgtaaag taagcttatc
    32041 ttatctggcg ccattctcct atcccttcta tcggcgctat ggctatgaac aatcatttga
    32101 taaaatcagt tatcaactaa acagtcgtga tgtgccgttt atcaaaaaaa aatctggaaa
    32161 aataaagcgt atggattttg aagatgcaaa agctgcaatc agaagaattt atgaacagat
    32221 gccggaaaac caacgagctg gtctgaagcg cgaagactgg tggtatacgt ataaattcaa
    32281 gcaaaaaggc aattaccagt ttgctttgca ttttgatgat aatgaggaag caacgggata
    32341 tatcgtttat cagcttgcaa cgtcttcctt tattattgcg gagtggggat ttttggatca
    32401 tgatgctttt tgcagccttg ttcgcttcgt aagttctcac aatggtgctt ttgaaacatt
    32461 tgaatattca tgcggctacg gcggtaatga tcaaaattat ctattagaaa atccatttgc
    32521 ttctgtaatg atcacacctt atatgatggc gaggatcgta gatatttctt tgtttttgga
    32581 aaattatcca tttaaaaaga gacaagctgc atttgcccta caaatagaag aagatcatta
    32641 tgcgaaatgg aatgaaggaa tcgtggaagt aacaatcgaa aatggaaaaa atcatctctc
    32701 aaaagtagaa caaacaaaac tcccaatcgt tcgaggaagt atccaacata tcacgcagct
    32761 attattaggg tatcgtaaag tggaagagtt ggtattccaa gaaagaatac aggtgacaaa
    32821 agaatatgaa gaaacgttaa gctcaatctt gccacagcaa cagccaattc ttaatgacta
    32881 tttttgataa aaaacgggtg atgacaatat ttttgtcacc acccttttgt ttttcatttg
    32941 gcatttgaag gaaaatgtta aagtaaatcc tcttttttcg taaatttgaa ttttttgttt
    33001 tcttttgttt tagggttttc ttttttgtgg tcttggattg cttctttcgt aatcttttcc
    33061 cgattttttt tagatgaatc taagcgttct gcgtatactt tttcttttgg cttatcattc
    33121 attggaaagg acctccctac attatttcat tctacctcta gtttatcatc tgttaaggac
    33181 tagtggaaac gttttgccta acttataagc tgattttttt agcagataag cttgcaagta
    33241 aaaaacaaac aagctacaat tgatttattg aaattgttcc tgtagctcag taggatagag
    33301 caatcgcctc ctaagcgata ggtcgctggt tcaattccag tcaggaacgt ataaataacc
    33361 cctgtatcct ttgcggtaca ggggtttgtt ttgtatttgt gccaaaaatg tgccaaacta
    33421 gttatcattt ttatataaac tatcgaacac agtattgatt ttttctttat cctgatcttc
    33481 aagctctcga acaatatgaa gataagtaga cattgtagtt tctaaactgc tatgtcctaa
    33541 acgtttcgat acgctaagta tatttactcc ttgataaagt aaaatagatg catgtgtatg
    33601 ccttagtcca tgcaaagtaa attgcttttc aatccctaat tcttttaatt ttttgcgcaa
    33661 atatttgctg acggcgtttg atgaaactaa tccatttttt aagttgaaaa aaacaaaatt
    33721 atgagggttt ttgatttcaa aattctcgaa taattctttt tgattgattt taaacttttt
    33781 taagagatca atcgtatgtt tatcaatgga aattttccta tttgaagttt cgttttttgt
    33841 ttttccccat tcatttaatt tataattcca tgttttatta atagtgatga tttgatcttc
    33901 gaaatcgata tcttcccatg ttaatcctag aagttcagca aatcgcattc cagtggcacc
    33961 agcaactaac acgagcatag gagaagagta ctgcgcagaa aggttttctt ctacgagttt
    34021 cattaaagat ttaaattgat cataatctaa atatttatct tcttttggct tcaatgaatc
    34081 ttttcctttg attactgctt ttctagttgg atcaaacgga attaatcctt cttctacggc
    34141 atctttcaac gacgctctaa tatggttatt aaacttaata acggtagatt ttacatggtc
    34201 tttagcatac ttatttaaaa agcgttgata tcccactcta tctaaatcag aaatcaatac
    34261 cgctggcata tatttcttta tgttcattaa cgtatcttcg tattttctat aagtgatagg
    34321 agatactgtt ccttctttat aaagttgcat ccaatcctca aagtaatctg ataataatag
    34381 atttttgcga tcccctttaa ggcctttgtt caagttatat tctaattcgt tggcggcatc
    34441 ttttgcttct ccttttgtct taaatcctga ttttcttatc ttcgtgtatt ttccgtcatc
    34501 ttttttgtat gaaatttcgt attgccaact atttccacgt ttgactaatc ttgccataat
    34561 tgaatcagct ctctttctct gatacaatag gaactataaa gaagcccatt gtttgggttt
    34621 tattattttt tgcacatcct ttttgcttgc cggcgcaagg atgtgctatt tgtcgtttta
    34681 atggtataat tggatgtgta ttagatcatc caatcagagg tgtttattat gattaaagtg
    34741 atttttaaaa gaataactga acttccagag tttagattat ttgttgatta ttggtatgtc
    34801 tggtttttta ttgttgcatt gctgataggt ctagatgtca tattagaaag aaaacttaag
    34861 taagagttga gttaataaat tgaattccta aatgagatat tttgtagccc atattttgtt
    34921 tgccgacatc acctaatact atggagctaa tcgttttttc taacagacca aaatcagata
    34981 atctatttaa gctaccatct attagctctt gtgaatagcc agacatgctg atatttccag
    35041 tgaaattttc gtttccacga ctcattaagc atgctaacaa ttgaatctca atcgatgtta
    35101 attgattcag tacaagaaga taatactcct cgttatccca tgaagcgttg ttaattcgaa
    35161 gtaaacaatt cttataaaga tttttataca tatctatttt attttgtgcc tttgattttt
    35221 ctacctcgtc atttatccct tcgaatattc caatgagttg gtccttgttc tctaagttga
    35281 aaacatcttc tggaatttga tcgcgaatgt tttctaatga ttcgtttaaa tttttgtaga
    35341 atttctcgat gcgtttgaaa cgcttctcgt ttttagaccc aaaataaagt gactgcacaa
    35401 cgccaccaat ataaggaatt gctccaatac cgccttcaac tattaattca agatattctt
    35461 ttttggttag tttttcattg ctattatcca tagttacctc ctattttgtc atttccttta
    35521 caagcattgt gactcctgat ggcactcttt tgtataggtt ttattattgt gcacaatcta
    35581 actcttagtg gggcgtggtt catttatttt ttacttactt tactattaat catatcccat
    35641 tgagcatagg atttttctat gttcgatcct cttgaactaa tttctcctgt aaaagttact
    35701 ttatcgccct ttgtaaaggt atcagcattg tttaagtcct tcgcaaaaat tacatatgaa
    35761 actttaggtg ttgcagaaat atcattccaa cttttatcat cgtactcttt gtctgctata
    35821 atggctattc tagtagtcat tgattcgata acagttcctt caaaagtata tgttttacca
    35881 ctaatatatt tagtaaaagc tgtattttgc tcagtagatg gagtaataga ataataacta
    35941 tctaagaaag caccccagtc atgattattt gtctctaaaa attcttcaaa ttgagttagg
    36001 cttttattgc tgctgttaga tgtagtagtt tgagtatcag atgatgagct ttcctgtttg
    36061 ttattgtcat ttgcctcgtt tgatgaggaa agcgagaaac ctacggtagt aaaaataatc
    36121 ccgataataa ggagaatcat aggtgttttc ttatttgttt ttttgataaa tcttacaatt
    36181 aacatgatta aacctataat aaataaaaca ataccagtaa aaccaaatat accgtccatt
    36241 aatagatcct ctttctcttt tgatattgaa tattataaac caagcaattc ttttttctta
    36301 aaatcgaatt cttcttgatt aataatccct tcatctaaca actctttata ctttttaatt
    36361 tcatctgcac ttgaaatttg tgtttctttg gaattattat ctaatataga ttgttgcttc
    36421 tctatatatt tttttaaatt ttccatttca ttccaatatt tttttgtaaa cataacggtg
    36481 ttttcatctt tcgtggccgc taatatacct ccgcgacttt cgtttccgcc tagcaaggta
    36541 aattgtatat aaccattact catacctggt ttttttaatt gtacggctga tatattttta
    36601 aaggggatag ttttttctcc tttaatacct tgattaacta aatttataaa tccttttcta
    36661 ataattgaaa tagaatcatc agttacttta atcaaggttt ttcctggaga ttttattaaa
    36721 atctcttttt ccattttttc ttcctcattt ctgtgatatg attttttttg tagaagctca
    36781 tatatgagga aagagcccgt gttgcagcac gggctttttt aatgttttgc tgaaatcggt
    36841 ttttttaata attcttgatg tattcataca tattgccttg cgtaagaata ttttttctta
    36901 aaatagcatt ggcagacagc ataacaagtg tatctgagct tattctgaat agaataatac
    36961 tccataaatt tttcgagatt aaactgagat tcatcagtca gttcgttctc aatatagata
    37021 tttaataaaa ttagaatagc tattttatct gcttctgttt caaattttga gtgaaaagtt
    37081 gtagaagtat cgtacaaaac tgaaaattca aaatgagagg cgctgaaatg tgcaagttca
    37141 tgagataaat gaaaggcttc tgcagtttca ccgtatagat tttcattcaa aaaaatgatt
    37201 ctgggttttg gatagtagaa accaggctct ttcatctcca tataaactac tttcaaattg
    37261 tattcgctca acatttcttt caatttcaaa tacatacaaa ccatcactcc aactattcat
    37321 tttcctctaa agctttagca attgcaatcg ctttacgcat tgtctcctta gatatttctt
    37381 ttccatcaaa agaaaaaaca gtatcgtctt ctgataaatc cacatgttta ggggtttctc
    37441 tttcttctct acctagaagg tagtctacag agacatcgaa atagtcagca atccgactta
    37501 attcatctga attaggagta ttatttttcc actttgctag ataaccgtta gaatatccaa
    37561 aattaatttc taactgccgt atagatatct ttttcctctt cgccaagtct tttattattt
    37621 cataggtatt catcgataaa acaacctttc taaatgttta caaaaaaagt ttagaaaaat
    37681 acgcagaaat aatttgacta attctgagta atgagctata ctatatcttg taaacagatt
    37741 taacaactaa aaagacaaca aaaaacacta ttgatatgta aatgcagacc gccaagaaag
    37801 ctttaaaatc aatgttttta tgtcttattt aattatgctc ttagtataga gtattactca
    37861 gatactgtca attgaattta gaaaaaagtt gttaaatttg tttacgaata taaaagaaag
    37921 gaatgagaaa tatgaacaca ccgcaaattt ttaatttcga acaaaacgaa gttcggacaa
    37981 ttttagtaaa tgatgaacca tattttgtag gcaaagacgt tgcgagtgtt ttgggttatt
    38041 caaacactaa agatgctttg tcgcggcatg tagatttgga agataagatg gggtcgcgaa
    38101 tcacgacctc aggtcaatca agagagatga caatcatcaa cgaatctggt ttgtacagtt
    38161 taatcttaaa atcaaaactt ccctctgcca aaaaatttaa acgttgggta acaagtgaag
    38221 tgttgccagc aattagaaaa catggaggtt atctaactcc agaaaaagta gaagaagctt
    38281 tgcttaatcc agatacaatc attcaattag caactcaact aaaagaagaa agaactggaa
    38341 gattaatcgc agaacaaaag attgcagagt acgaacctaa aatctcctat ttagatagca
    38401 tattatcttc tacagattca gtaacaatta gtcagattgc agcagattat gggatgtctc
    38461 cacaacagat gaataaatta cttcataaac taggtattca gaaaaaagtc ggtaaccaat
    38521 ggttattgtg caaaaaacac atgaaccaag gatacacaaa atctcataca actgagatcc
    38581 cgaaagccga tggtggcact aaaattgtaa tgaataccaa atggacacag aaagggcgtc
    38641 tatttatcta cgaattacta aaaaaagaag gatattaccc tcaaatggat ttagaggaaa
    38701 ttggttagaa aggagtttta gtatgactga cattgcagaa atcactcaac gagatagaga
    38761 aaaaatcaaa gaatatgtcg aaagttcaaa gttcttaact tacaccatgc ttgctgaaag
    38821 atttggaatt agcaaaagct acttatcttt aattttaaac ggtaaaaaga cttctgcaga
    38881 agcaaacaga attatagatt cgattatcac tatgtacgaa ttgtaaaggg aggaacagct
    38941 aatgcaatat ctagaagcaa aaatcccaat tccagaaggc tatgtaatta tctcccaagt
    39001 ggattatgag gagttaaaaa aagctgatga tactggtaga tggatgacgt tgccagaagt
    39061 gctagaacgg attaacagaa aatatgattg gtttacttct agagttttaa agaacccaag
    39121 atatagaaat attatcgata tcgagaaaaa caaaaatgga tttgtctatt atccagttga
    39181 aggaagagac acatatctat ttttaagaag taaaacactt gaatttttag aaacaaattt
    39241 ttcggaaatc ttaaggaggc aagcggatgg gaaaatttaa tagagcgcta gtgttcagcg
    39301 caccgctaat catctacgct ttagaacttt ggggaagcag gcaagcgttg ataggaacga
    39361 ttgtttacat ggtttggatt tttatggggc ttgatgaagc tgaagctgag tacagagcga
    39421 aaaagccaac cgagggggct gactaaaaat gaatagaaaa gagaaactag aatgtatatt
    39481 actattactc agtttaattc tttcactaat ttctctattg ggaagtttgt atttttgata
    39541 tcaacaattt tgtggatttg ggttctattt agagtaaata tcatttttgt ttggtgatta
    39601 aggagtttat taaaattaat tttccctact tcaaatgcaa ggtaacaaga tatagcactt
    39661 ttaggaggaa tatttagcgg tacagcttca gagtatattc tattatcatc gactgatcct
    39721 cctttagcaa ttaatttctt aaatggagta gctgaccatc tgcggtttaa gttagcggat
    39781 gaaagttcta aattaactaa catagctggt tctgttgaat agttagaaat gattactttt
    39841 gtataaatca tatctgcagc gaagtaagaa gcattaagtt caacttctag ttgagggcgc
    39901 attcctttta tttttatccc tgttaaaaac gtactcaata taaaacttat tattgacatc
    39961 cattgaaaaa ttgttaagtg aaaaaaattc aaaataaaca ccaccagttt ttaactaaat
    40021 tataccaaaa aggagagaag aaataatgca agaattagta attttgaaaa ataaagaagc
    40081 tgtgactacg agcttacaag tggcagaaag cttcgagaaa aaacatcaac atgttttaag
    40141 agatattgat gcactaaaaa aagatgtgtc caattttgga cagatgtttg tagaaggtaa
    40201 tgaaccagat tcatatggca gaaatcgacg agttttcttc attagtagag atggattttt
    40261 cttgctggct atggggttta caggaaagaa agctatctac ttcaaacaaa aatacattga
    40321 agcattcaac gaaatggaag atgttattcg caagaatact gttcctcaaa caattgaaga
    40381 tatgatgatc tatcaattag aagaaatgaa agatgttaaa aaagatgttt ccatgcttaa
    40441 agatactatg cgaattagcg gacaacaaga gtttgaaatt aagcaaaaag gaaatatgaa
    40501 agttatggga gttctagggg gaaaagaaag ccgagcttat gaagaaatca gcaaaaaagt
    40561 attctcaaaa ttttggtctg aatttaaacg taccttttca atcccaagat atggcgagtt
    40621 acctcgtaag agattcgatg atgctgtttc atttattgaa atgtggttgc cagaaactgc
    40681 gatccgtatg gaaattgatc aactgaacag acaacagaga ctttttggtg atgacaatga
    40741 atagagctga agcgctaaga atagggacgg caattgctaa ttgctggtgg aaatactata
    40801 aaccaatcat cctaagtcaa caacatattg acaagcaaaa agcatggcaa caaataaaaa
    40861 agtgactccg ccggcaagca aagagtcaca aagaaaacac atcataagga gattttagca
    40921 tatggaaaaa gaactttcca ctctagatca atatttgatt gatcctgatt ggggcaagcc
    40981 gaaaattgag gaaacaagtg gtcgaaaaat cagacgaaat cttttgacga atgaagaact
    41041 agcttgggat caagatgatt taggcaacca tgtaactatt tgggatcatg tttatcttat
    41101 ccatctatcg aagcattcga ataaacctga atatatttac gtcatcgaag atggcttgat
    41161 tgatgcgcta gaagagtacg acagagataa cttgattgat atctcttatt acggaccagg
    41221 taagaaatac attgctgaaa tggaggcaga atttgatgag tgaaatcaaa gggacaacga
    41281 actttgaaaa actttttagt cgtaagttaa ataaaattct caagaaaaaa ggaaattttg
    41341 attatttatc ttgggctcac gcgtgggaga ttatgaaaaa gaatgatcca caggcaacgg
    41401 taactattaa tgagtacaaa cactacaggg ttgtttctgg aactcatcaa gactttcttg
    41461 ttgaggaata taaacctttt cttatggatg aaactgggac ttatgtatct gtctcagtaa
    41521 cggttaaagg acacacggaa accgaattat ttcctgtttt agattatcga aaccaaccag
    41581 ttgttaaacc aaatgcaatg caaatcaata actcattgaa gcgatgcttt gtgaaagcat
    41641 tggctctaca cggactggga ttatatgtat ttcaagggga agatattcca acaccaccta
    41701 gaatcgatac aaagaaatta aacatgctag agacgattct agaagctttc aatgagcaga
    41761 tgggtaaaga tatgaccaaa accttaatcg aatatgttaa tgagcagaca gataaattag
    41821 ggctcttagc tgataacgtt gaaactattg aacagttaag ctatgagcaa tgtgccttga
    41881 tggagcgagc aatagcagct aagagaaaag aattagataa gaagtgatat gagtgtttaa
    41941 accattaatc gattcatatt cagcggttct gaaaaagttc aaaggaaaag acataagcgc
    42001 aaccatcaat gaggaagtga acattgatcg actaaagacg atgtatgacg gctacgatgg
    42061 tgatcgagtc attgaaattc gttttattga tcctagacgt ttcaccgtac agcaacgaaa
    42121 cttcatctat gcgctgatag gcgatatttt tatcgataca ggcatgccaa cggacttctg
    42181 gaaggaattc ttctactttc gttttgaagg tgtcacaggg cgcaaaataa gcctgaaaga
    42241 cgaatcgaat acaactgtga gtgatgccaa tgtcttagca aatatcatct tagatttcat
    42301 ctttgaacat catattcctt tcaaagaagg ctatgagatt ttacctgcga atcaagaata
    42361 ttacttctac aaatgcatca caaaaagagt ctgctgcatc tgtggcaaaa caggagctga
    42421 catcgatcac tttgacaaag cgctaggaag acgaaagcgc aaagaagttg atcatgcaga
    42481 gtacacattt gcagcactct gcagaatcca tcacacagag aagcacaaaa taggtgtgat
    42541 taatttcaaa aataaatatc aaatcaaagg gatcaaatta aaccagaaaa caatcaaaaa
    42601 gttaaatatt ggagggtaaa aatgacagaa catcgaagtt attatgcgat tataccagcc
    42661 aacgtaaggt acgacaaaag acttaaacca aatactaagt tgttatacgg agagataacg
    42721 gccttgtgta atgaaagagg cttttgttgg gcaggcaatg agtactttgc agatttatat
    42781 ggtgtgaata aagagaccat atcgcgatgg gtaagtgatt tgattaagtt tggatacttg
    42841 aatcgggaaa tcatttacaa agagggtacc aatcaaataa tcaataggta cctacgaatt
    42901 aatcaatacc ctattgacga aaaacgcaat acccctattg acgaaaaagt caaagataat
    42961 aatacatcta ttaataatac atttaataat acaaaagaat atataagaga gttaccgcct
    43021 tcgaaaaaat cgaaggctaa gcccgtccgt cataaatacg gagagtataa aaatgttctt
    43081 ttgtcagatg agcagatgga gaaactcaaa acagaattcc ctaatgatta ccaagagcga
    43141 atcgaacgac tgtcagagta ttgtgaatca tctggtaaga cttataaaaa ctatttggca
    43201 actattcgaa gttgggcaag gaaagaaaaa agtgaaccta agaacgcaag cagtggatac
    43261 aagcgcacag gaagacgaga gaagcttcct gaatgggcaa tcgaccaaga agcctatctc
    43321 aagaaaaaag cgctagaacg agctaataga caatcaaaag caccattcta agaggtggaa
    43381 aaatgaagat cgattatcta gaactaatta atgaaatagc gaattataaa aagggcgagg
    43441 aattagacgt cctgagagac gtatatgatc aactcgaaga agctggaatt gaaggaatta
    43501 agaatgatcg ttcgagttgg agtaagctca gatactattt cgcactttat atcgatacaa
    43561 cacaattaag aaatttagca tataccaaat tactatttgt tgattgtgtt aaaggcttgc
    43621 aaaaacatct taatgaactt gagcaggtgt aatcagatgg acctaaagac atttacagca
    43681 cagattgaac taatgcatca agaagcttta agacaaagtg tatcgtacga agacaagtgg
    43741 ctcaacacgt tccatggcgg acgtgagagc gcacttgatc aagtactcaa attactgaaa
    43801 ggagaatgtc gggatggata agaaagcggc aatgcagcga attatcgaat tgacttattc
    43861 agaagattgg caaaatgaca aagaagctgc ttcagaagtg atgaggcttg gaagagcgat
    43921 gtgggcagac aagagcaaca agccaagacc acgaaaaatc gcaatttggc acggtgacaa
    43981 acttctagtg atagggacag ctgaacagtt agcaagtctc acaggcttgc acgagaaaat
    44041 cgtgaggaaa agagcaaggt gtggctacac agacgctaag aagagaacgt ttagatacgt
    44101 ggaggaatca tcatgacaac agaagaagtg attcaaatgc gtattcgaag ccttcagcgt
    44161 gagattgacg atctggaacg aacaaaggca gtgatggtca atgaaacggc gagaaaggca
    44221 atcgatttgc acatagagaa tttaagaagg gaaatccatc gattggagga atgagcgtgg
    44281 ataagaaagc agcaatgaaa agaattgctg aattaaccaa gtcagaatct tggcaagaag
    44341 acaaagaaat agttgcagaa gtccaaaagc tcggtaaatc aatgtggact gaaaagccca
    44401 aacggagaac gccgagaaaa attgcaatct ggcatgatga ccgaatttta gtaacaggta
    44461 ctgctgaaca gttatctgaa attactggat taagcaaaaa cattatctgg gatagagcta
    44521 ggagcttatg gattgattca aaaggacgac agtttaggta tgtggaggag agataatgga
    44581 tctcattaca caatacagtg acatcatcct caagaaaatc atgatgaaga ttcagaaaga
    44641 taaaaaatca aaagaacgag ctgaattagt taagttagaa atggctgaaa caggagcagg
    44701 agtgcgaagt agcaggcatt ggaaagcagc agcaaacatt gaattttatt acaacgaaat
    44761 tcaaaaaggg ttcgatcaga tgcgtgagct ggatcggcaa acaaattgga gcaagaaact
    44821 tcatcaagat cgtttcaaat ttgtagagaa gtataaagaa atattagaag agtatttgag
    44881 gaggacagca aatgataaaa aaactcgttc aattcagcat ggatttatat gatatcgaat
    44941 caggagcaac actatctgtg gaatcggacc atctaatcat aaattttggt ggaaagcgcc
    45001 agattatttt gtgggtagtt gatgatgtac tgtttccaga aattgttcat gatttcgaag
    45061 aatcaaaagc ggttgagttt gaaatagtga aaaaagtaat ggaattgatt gaaaaatacg
    45121 aggaggacag cgaatgatac cgaagtttag agcgtgggat aaacgaaaga acgtaatgag
    45181 agatgtagcc gtcttgcatt ttactaaaaa cggcaaaaca aactttattg aatattggat
    45241 aaatcctacc gaattgaaat catatcacgt gcgaaacatc gacctcatgc aatccacagg
    45301 aatgaaagat aagaatggtg tggatatatt tgaaggggat atagtattag tcagcgtgcg
    45361 aaatggcttc gattacttag ataataaagt ctgtattgtc aaaaattcaa tagattattc
    45421 cggattagtt tgtgccactg ttgatgaaga cttagagtat caaattttta acacagagct
    45481 gtttgaagaa tacacgtacg aagtcaccgg aaatatatac gagaatagcg agttattgga
    45541 ggaacagcga tgaataaaca ggaagcaatc aaaaagttag aaagtattaa agcgatagga
    45601 aatgatgcaa tagctgcttg ctataacgag agtataaatt caggtattac gttaatgaaa
    45661 aaaatagacg aaccgcagaa accagttatt ccacaactcg tggccggttg gcttgagaaa
    45721 tctacggacc cttttacaaa agctgaaaaa atagcgtatt taatcaaatc taaagatggt
    45781 gattcatatt atttctgtga ttggtttgta cgagatggca tagtgacgca agagcaagga
    45841 gaagaattac tcgcttgggc aacaagacaa tcatatgaaa cactattgag cctatacaac
    45901 ggctacgagg ttgagaaaga gccgttatgg gcaataaaga atgccgatgg aaactatctt
    45961 actaaatgtg ctttatgggg aaaagatgga gtaaattata gttttgaatg caatccatct
    46021 catcgattgc ttttcactga taaagcaaca gcggatgctg cagcattgtt ggtgaatgga
    46081 acagtggaag aggtggtaga aagatgaaac taaaagacgg attttacgct agcagtcacg
    46141 gtatcggcgg tttaatgcta gatatgccga caaagaaccc taaaacacgc aagaaatcaa
    46201 aattcaaagt cggtgacatg gtccgctgtg aagcagaaga gttcgtttat ccgttcagag
    46261 gatacgttaa aaagatactg tcaaactcag caatcattcg tattgaaaat acaatgaagt
    46321 gtgatcgttc gactgcaaaa cacaagcatt atttagctgt agcgagatta gttgacatgg
    46381 aagtaatcaa gagcaaataa aaaaagccgg atcgctccga ctgattcaat aaatccaaca
    46441 catttattat atcacataaa ggagcggttt gacttgatgc aattgttacg agaggtagat
    46501 ttcaaacaga caagatgtaa tgcgagagat gtgctgaaga actttcggcg tttggagcgg
    46561 atggcaggtc gctctttgat agatattaag tcgccgatta taacggatat gccgaaggca
    46621 ccgaagcatg gcaataaggc agaagacgcg attattcaga tgatggatat agaaacggag
    46681 agagatgcga ttctagcggc tttgatggct cttagtctga ttagtcgtca gatactctac
    46741 tacagcttct gtgtgccaga tagcttctca aactacagaa ttagccgtga agtgggttat
    46801 tcagaaagaa gtatacaacg gatgaagtcg gaagctctaa tagagtttgc agaagcatat
    46861 aaacacggaa aaataattgc ttataaataa tttggcggtt ttttggcgga atgatggcgg
    46921 tttttagaca tttaccagtg ttattatggt agtgtcgaaa gattaggaaa caggatcgac
    46981 aaaataaacg aagggaggca atctccctca tcgttttaaa cttcttctta gatagacagc
    47041 aactaattat gaagaaaagg atgtgaattc aactcctcct aaattcttca tcggttgctg
    47101 tttattttga ttagacagca gcactcacaa aactaaacat gttcttgtcg tctttcaact
    47161 gctgctgtct attaatttat gtattggagg gaagaaaaat gaaattatca gtagaaggca
    47221 ctccagaaga aatacaagaa ttgctccaag ctattggtag tagcaaggag caaaaggtaa
    47281 gtgtttctaa ttcagatatt gacggtattt gcaattgttt aaacagagaa aaaatatcta
    47341 atccttacta agagaaaata tgttcgttaa tgaatttcca attttcctct gtagctctac
    47401 cttgataatt tttttgcagt tcacagatga ataaggaatc gttattatca agtactgtat
    47461 ttaatttttc acacatttga tttggattca aattagtttt aactaaccaa aaagattttt
    47521 gtagctttat atatgcccca aattctttta ttatttcaaa tactttatca tacttttgcc
    47581 ctgggttatt aagatcataa ctaatcatgt agggtttata catgttgtct tgcacatcct
    47641 tgttttatat ttcagcggac cactcgctga taaataaaat tatacgctta gtatttattt
    47701 tcacaatatt aatttatcgt aataactttt gagtaaatag aacaaaaaac ctgcactagt
    47761 ttccgctagt acaggcagtg actatatcgg ttgataatct agcatatatt aaaaataatt
    47821 gcaagaaaag aaatttatag tggtttatac caaattatca aagcaatgtt attttgttgc
    47881 tgtctattgt tttttaatta ttcacacgat aactaaaggt gggtgaagag aaatgattcc
    47941 attaataatt tcaatttttg cgctctgtct taatgtctat atgattggat ttaaaaatgg
    48001 gcaaaataaa aaatagtagc agccaagaat aattttatag tgtcactgtg gcggaaaggg
    48061 tagacgctaa gcatgtgtgc taggtcaatg cttcggcaac catgcaaggt tcgattcctt
    48121 gccagcgaca ttaaatgcct atgacggtta cgactaccga aaaaagatcg ttaagaagct
    48181 atacggtgct acgtacggca atgtagtaag tgtgctatct gtgtacacca ccaagcttcg
    48241 gtcactgtgg cggaagtaga agacgcagcg gtaaatggcg agtagcctcg tgagagcctg
    48301 gtaagttctc gtgagtggtg caatcccact ccagcgactt taagcaaccg aggcatcggc
    48361 ggtttaaaaa tataggggtg cgcaatttcg tacgcgtttt gtgcatcgtg caagttacta
    48421 ttacatatta gatcactctt tgagtggtct ttttattttt gcacaaagga ggaaacaaca
    48481 atgtatagac cacaatactt agaacagaag tatgaagtaa tcactgttca taaaggtaat
    48541 ggcgaaaaag tatatgagta tagaagacca ataaagagcg atacatataa acgaaaggaa
    48601 aacaatgaag ttattccatt gtatggcaaa agaatagcta agcattaaat aagattgcga
    48661 aaggagacgg aacatgaccg aggaattcta tagatggcta ttacagttga caagagaaga
    48721 tcgtttggtt aagttctatc agtctcctaa atggcgcagg cttagagaga aagcgatgaa
    48781 acgagatcac tatgaatgcc aagagtgtag aagactaggt aagtatcata gagtagagaa
    48841 cgttcatcat ataaaggaag tcaaggatag acctgactta gctttagatt tagataatct
    48901 tatttgttta tgtgttgaac atcataatga agttcatggc agatatctta cagcattaga
    48961 taaacaagag aagaagatag aaagctttgc taacttcgat gcaagtgaaa ggtggtaagt
    49021 gcatgatcat caatgataat ggcagagagt atgatacaga aaagattgaa gagtattcat
    49081 cttatactca gggattaatt aaacgtttga tatacgttcg ctatgtaggt attagggatc
    49141 tgttatcaga taactgttgt agtaaataca aagtgaatca agtaagagaa gcgttgaata
    49201 aagataataa cgtcgaaaga ataaaaaatg tttttggata tagtattgaa gagattaatt
    49261 attacattga cttcgctgaa gctttcattc cgatggtgag ataacccccc cttaaaataa
    49321 atcgcaaatt ttttgggggt gatgaaacgg agggggctgt caggaaaaga gattttttcg
    49381 aactttatca tgaaaggagg gctaaaatgt ttaaaaacga attgtctcaa aatcgctaca
    49441 gagaaaaatt acgccgctct ttaataagcc aattggaaag tcagaaaaca aatattgagc
    49501 cattcttaga taatgttgat cgttatatca gtttatggga aacggcgata tcactggaag
    49561 aagatatatc cgagaacggc attagactgg agaatggtaa aaagaatgaa tcagtagcgt
    49621 tgcttgtttc tgtcaacaaa caaatgggat tgatgttgga taaacttgcc attactcctg
    49681 aattggtagg tgaagcaaat gaatcaattc ctgagttata agcatattga aaattggttc
    49741 aaagctatag aagaaggcac tatcaaggta tgcaaagagc aattattgct aaaaaattat
    49801 ctagaagaaa gagtctttac tagagaagat atttacttcg ataagcagat ggtagaggat
    49861 tcaatcaata taccagcaca atactttcca ttcgaattaa ttccgtggga aaaatttcta
    49921 caatgtttta tttatggtgt tcgatggaaa aaagataaaa cactagtgtt caatagatat
    49981 ctttcattaa tgggacgtgg taatggtaaa actggttttg cttcttggaa caacttcttt
    50041 ctactaaccg ctaaacacgg tattaaaaat tatgatattg atatctatgc caataatgaa
    50101 agccaagcaa agactagttt tgatgatgta tttaaagtaa ttaaagatca tcctgattta
    50161 gataaaaaag tatttaaagc tacgaaggaa gttattcaaa atatcgctac aaacagcaaa
    50221 cttcgttata acacggcaaa tgctagaaca aaagatggga agcgaccagg tgcaaaccgc
    50281 tttgatgaaa ttcacgaaaa tgaagattat tcaatgataa atgtggctac ttctggtggt
    50341 ggtaaaattc gagattatag agaattttat gatacaacta atggtcatgt tcgtggtggt
    50401 ccgcttgatg acattataga agaatcaaaa atgattcttt ctggagaact tggaattgac
    50461 aaggatggag cagaattttc tagtttgttt ccatttattt gtcgcttgga taacgataat
    50521 gaagttgatg atcccgacat gtgggaaaaa gcttgtccaa ctattaatta caatgcagat
    50581 ttaaaacgga aaatgtttca agaatactct caaatgcaac gtaatgctgg tttaagactt
    50641 acgttcatga ccaaacgaat gaacagacct atggaagata cacgatttgc tgttgcttca
    50701 tatgatgatg ttctgcatac gaaagaaaaa gaatttcctg aaaaaatgga tgaagtgata
    50761 ggaacagtcg attttgctga tagacgagat tttgccagcg ttgggttgct aggaaaatac
    50821 gataaagatg tttattttac acaacatact tttatccacg aatcagccct tcgattacaa
    50881 aacatcaaac gagaggttat agatatttct atagatcaag gaaaatcaca gatcgttcat
    50941 ggaaaaaata tagaagctga ttatattgta ggttggtttc ttgaaatgag taataaatat
    51001 tatattaaaa aaatcgctat ggatatgtac cgtgcaaaaa tattgaagcc cgctttagaa
    51061 gaagcaggtt ttactgtgga aattgttcga agcggatctg ttacacatgg tatgttaaaa
    51121 gatctggttg atgacctttt tattaatcaa cgtttatttt ttggtgacga tgcgattatg
    51181 cgttggtatt gcatgaatgt atatgaagag catatttcta atggaaatat acgctatgaa
    51241 aaaatagaac ctgaaactag aaaaacggat ggcttttttt cattccttca tggtttgaat
    51301 tttttagatg atatttatga ttctgctcct gtaacagtca caaatagctc agtagaaaat
    51361 acaggaactg gatttactcc tctagtattc taacttgaaa ggaggtgaga aagtggggat
    51421 ttttcaaaag gcggtaggat acttcacaaa aaaagcaacg gttcctttag aagaatactt
    51481 ttgtaaattg caagttgatt ttgtgtatcg aaaatttgcg attgaaactt gtattgattt
    51541 gattgcaaat gcgatgagta aagcggaatt caagtcatat gaagatggaa aaaataaaaa
    51601 gaatgatctt tactataggc tgaatgtagc tcctaataag aaaaataatg caacagaatt
    51661 tagaaaaaaa ctgatcagga gattaatatt ctacaatgaa gtattgatcg tttctccgtc
    51721 taataattct agcgaaatat ttattgcgga tagttgggat gtcacagaat atgcattgaa
    51781 agatgatgtg ttttctcaag tgcaaattaa caacatagtc cttgatagag aatttctaga
    51841 aagtgatgtt atctatataa aatacgcaga tcaacaaatt aggcaactag tcgatgcgta
    51901 ttatcaagcg tatgggaaac tcatttctag tgccatgaat gtttacaagc gctctaacgc
    51961 tcgtagatac gtactgaaag ggaatttatt ccgaccgcaa gacaatacaa cacaagatca
    52021 aatcaataaa atgatgacat cacaatttaa ggcttttatg gaagctgata atgcaggtgc
    52081 ggtatttcaa ttacaaaatg agtacacatt agaagatttc agcggaaact tccaaagcaa
    52141 ttcaagagat ataaaaaact taatagacga catctttgag atgacagcag cagcgtttca
    52201 cgttccgaaa aacctactaa agggagacat gagtgggtta tcggatcaag tggacgcttt
    52261 tttaatgttc gaaatcatac cgattgctga acttattcag gatgcgttta acgctagtct
    52321 ctatgaagta gaagaatact tgtcagggaa ttttgtacgt gtggatacaa ctatgatcaa
    52381 gattactagc ttcaaagatt tggttgacgc tattgatgta ggcattagaa atggagtatt
    52441 tacaatcaac gaaggaagag aacgcgttgg aaatgatcgc tctgataagg cgatggcaga
    52501 tgaaatattt ataactaaaa acaatcaaca agtatcgaaa ggaggtgagg cgaatgacga
    52561 caatgaaaac atttctagca gtaaagaatg aaggcgcagt accgcaaatt tttattcagg
    52621 gatttattgg ttctagttgg ttctttgaag ggaatactga caagggaatc aaaaatattt
    52681 tggatagtct aggtgatcaa gaagaaattg aagtagtaat taattcaaac ggtggagacg
    52741 tatttcaagg gattgctatt gggaacttac ttaagtcaaa taaagcaaaa gttaacgttg
    52801 tgattaacgg cttagccgct agtgctgctt caattatcgc aatggctggc gatactataa
    52861 aaatctacaa caatgcacaa ttgatgattc accgcgcttc cacatacgga gaaggaaatg
    52921 tcgatgactt ccgtacgatt gctgaccaac tggaatcaat tgataaatcg gtaaaggctt
    52981 catataaaac acgattcaat ggcacagatg aagcattgca agaacttctt gaaaaagaat
    53041 cgtttatgga tgcagaaaca gctttgagtt atggattggt cgatgaaatt atcgatgcag
    53101 aaaatagctc aggtactgaa gctaaaaaag aacaaagcgt tgaagaaatt ttgaatgacg
    53161 ttaaagaaaa aagagcagaa aaaattgctg catttacagc agcattaaat aaaacatttg
    53221 gacaaggaga tgtaaaataa tgacagttaa aaatttaaaa ggtgtaacag ctgcaagcga
    53281 ccaattgatg aaagctttta aagatggtaa cgaagaatct tttagcgcag ctatggtaag
    53341 cttatctaag gaaattcagg ataaaatttt agaagaagca acagcaaaaa atcaagatca
    53401 attagtatta atgaaccgtg gtcagcgtgt attaactaca caagaaacaa aattctataa
    53461 cgaagtagtg aaaaacgaag gttttgcagg ggtcgaagaa ttagtgccag ctactgtatt
    53521 tgaacgtgta tttgaagatt tagaacaatc tcatccacta ttgcaaaaaa ttacttttgt
    53581 taacacaact ggtgtaacag aatggattgt gtcacgtgga gtcaatccag catggtgggg
    53641 taaactttgc gaagctgtta aaaaagtttt agataatggc tttgatgtaa ttaacatgaa
    53701 gcagttcaag ctatcaggtt atattcctgt atgtaaggca atgcttgatt taggtccagt
    53761 atggttagat cgttatgtcc gtactgtttt agtagaatca ttgagaattg cattagaaca
    53821 agcaattgtt gatggtactg gtaaagatat gccagtcgga atgatgcgtg acatgagcaa
    53881 acaaactagc ggagaatatg ctgaaaaaaa agcagaacct attacagctt tagatgctgt
    53941 aactatgggc ggtttgatgg cgcgactatc aaaattcaat atcgaaggtg tgaatgatcc
    54001 gatttatcgt aatgtgaatc cttctgatgt ggtcctaatt gtgaatccaa ctgattactg
    54061 gtctaaagta ttcccagcta agactgtact aactgctaat ggagaatacg tacaagtatt
    54121 gccagtacca gtttcagatt tgcagtcaac ggctgtgcca gaaggaaaag cagttattgg
    54181 ggtagcctca gattacttca tgggtgtagg atctacacta aaaattgaag cttcagatga
    54241 ataccatttt gttgaagacg aacgcattta tctagctaaa caatatgcaa acggtcaacc
    54301 taaacgtaac gatagtttca ttgtattaga tattagcgct ttgggaacta ctactacaac
    54361 tacaaaacca acaaccacaa caactacaac acaagcgtag gtgatcagaa tgaagtatat
    54421 tctttgtcag ccggcaatca atcggtttaa atgggagctt gaagtttgtt taactaatct
    54481 gaagaaacta ggaatcaaag atatcgtatt gcttttcagc agacacgatg atcagattcc
    54541 tatttttttt gagaaggaat atggtgttga agttcatgtg tacgatgatc tgcgggacga
    54601 caaagagtat attccttcga ttaaaccata tttatggtgg aaatatttag aagaagatca
    54661 ttcgcgtgag gacgaccgat atttctatat cgattcggat gtcattttca ataaaagaat
    54721 taatttgcgc aaattgcctt ctaaagatga tgtttggtat tgtagcgact gctgtagtta
    54781 tctaagtctt gattatatta gaagctgtga aaacggagaa aatattctaa aagatatggc
    54841 aaacattgta aatgttacag tagaatcttt ggaaactata aacactaatt caggaggcgc
    54901 acagtgggtt attaaccgtc ctaaagcgaa ttattggaaa aaggtttatc tggattctaa
    54961 tcggctatat cgctacctta gagggcaaaa aacaaatata caaatctgga cagccgagat
    55021 gtgggcacag ctttggaaca tgatgtattt caatattggt cctaaagttc acgaggaatt
    55081 agacttttgt tttgctactg atccaataga aaaagttaaa gaagtaaaaa tcttacacaa
    55141 tgctggagta acaacaaacg atgaagattt atttttcaaa gggagatacg tgacttctac
    55201 gccttttgat gaagatttat catttgtaaa caagaaaaaa tgctcttacg catatgttaa
    55261 agcaattaag gcggtggtta gatgacgcct gaacaagtga ctgaagaatt gctaatagct
    55321 gtgaaggata atatttacgt tacctggaac gaagaagatg agtcaattaa aaagatgata
    55381 gctaaaaatg ctgtttatct tcaaagtaaa gtgagtacaa cactttcttt ttctcctgaa
    55441 agcttagaat acggattgct aatcgaaaga tgtagatacg actggaatcg tgctttagat
    55501 gagtttgaac aaaatttcgc tagtgagtta ttaggtttca ttcaacatta tgcgctacaa
    55561 gaatatattg caggtgatgt gaatggcgaa taatcgtaga ctcgaagaaa cattcaacga
    55621 tggttggtta aagattttga cgcaaactac caaaagaaat gaactaggaa aaaagattgg
    55681 tgtagaagat acagaaatca cttctttaaa atttagaaat ctttccatga gagatagtga
    55741 tataacagct atggatgcga tgggatcgaa attaactaag aaagtaaaga ctccatttca
    55801 tccaatcgcc aagaaattta ataaagatca atattttatc gtaatcgata gtatgcgtta
    55861 caacgttatc tatgccgatt acgataattt ttatatctat ttttatcttg aaagtgtggg
    55921 tgaatatggt gattgataat tctaaagaaa aagaacgttt aaataagcaa atttctgcta
    55981 tcaaaacttc cttagaagag cattttggcc tcaaactctt tcaagactcc gtaggcgagg
    56041 atgagctacc tgatgatttt aattacttca ttctcgaaac aggagaaata gaaatgatca
    56101 ctgagccaaa atatagcgtg ggtcaaaatc tatatctaac tttctattca gaaaatagag
    56161 aagatttaac aggagactca ctagatatta tttcattgat tcaaaatcgt tcgattcgtt
    56221 ttcagagaat ggatcccaat catttaaaac tagagaacca agatcgctat atcgatcaat
    56281 tggtatttac gtttagacga ttattgaaga gtgattgtca tggctaaaaa tagttgggag
    56341 ctaaaaataa atggacatga tgaacttctt gtgcggatgg aacgctattc aagcgagagc
    56401 gaacgactga ttaacgaagc attgaaatca aaaggttcgg ctattgcagt ggataggatt
    56461 acagaaaaaa ttcctgtttc tgaagcagat ttaagaagag ggcaccaaca cgcaaaaaat
    56521 agtcgtccac ttaagactca atacattaat ttgggtttca tcattagacc tacaagaaaa
    56581 tttgagtatt taaaatatcc tgatttgggg ataggtactt ctaaaagaaa tcagccggac
    56641 gaatttatga gaagaggatt aggtcttgca cttgatccaa ttacagaact tctgattcgt
    56701 caattcgata aattaaataa atagggggaa caacaatggc taaaacaaaa actgtagtaa
    56761 caacgttcga taacgtaagt atcaaacgaa ttgcttttaa ttttaagaac gcaggaaatg
    56821 caatcgcaac gaattgtaat ggacaattag atggcgaaac agaaatgcaa acggtggtta
    56881 aaaaatgtgg agcgacagaa gtaaaatcaa aatctaaacc aatcaatatg acggtaacaa
    56941 ttactgcaca tgtaccgatg gaagtttatc gacgtttcaa tgggttgaaa caagatggac
    57001 gtattaaacc aggcatttac tcttacggtc ctgattccgt aggcgaagat ttctcacttg
    57061 ctgcagagat cgtggatgac ttcgaagaaa atagaaagtt agttggtatg ttagcatgca
    57121 cttcgaatac aggattaaca ttctctattg aaaatggtgc ggatgaagta gctgcgttag
    57181 aactagaaac aaaagttatg caagatgaat ttggtaaatt ttatcatgaa gcaattgttg
    57241 cagaacttga agaagactta acagatcaat ggatgacgaa tctatctgct gatgtgatta
    57301 aaaaaacttc agttgtgaca actacggcca ctcaatcaca gtaaaaaaaa cggaggtagc
    57361 gaaatgaacg aagattactc aaaaattgaa ctaaacgatg gaacaatttt gaatttagaa
    57421 cctaaactga atatcaagaa attattgatg atcaatagag attttaacac agacgagttt
    57481 gcaaaaatga ctgtgggaaa aggatccatg gatatttctg ttattcaagg tgcaaaggct
    57541 gtgtatattg cttaccgcca agcgaacatg actgattata tttcattcga tgaatttatc
    57601 gataaatggg attttgatat ggctactgcc agctatattt atcaattgat gatgttcaaa
    57661 caagcacgcg atgcttatca aaaagaattt gaaaaagcaa ataaggaaaa aaagcttcaa
    57721 aagtaaaaat tccaaagctc ttagttgaaa cgtgggtcga tgtctattcg atgttgaccg
    57781 acgttttttc tatgccttca gatttggttt taagcgatat ctgtttagat gacattttgc
    57841 aaatggctta caacaagagt gcttatgaag gatggaaaaa ctatgcaata aaccaatccc
    57901 agaaaaacta aagaaaggag gtaaaaaatg gctaaaaaga gaacagaagc agaagtaact
    57961 ttcatagcta acgatgacgg attgaaatct acgttaaaag aaatcagtgc tgaattaact
    58021 aaaaatagag cagaattaaa actagaacaa gctcaattac aacagactgg ttctgaatca
    58081 gacaagttag gaagtaaatt atcttcttta gaaaagcagt atgaattaca aagtcaaaaa
    58141 gttgaagtaa ctagccaacg tttagccaat gcgaaaaaat attatggaga aaattccacc
    58201 gaagttcaga aacttgaaag agaactgatt aatcaacaaa cagcgcaaca acgtttgtca
    58261 aacgaaattg ataaaacgag taatgcacta gctcaagcaa aaggcgaaat acagacgtac
    58321 gagtctacaa tgcaacagtt ggatagcgaa caaaaaaatg ttcaagctag tgcttctctg
    58381 attgaatccg aatacaaaaa atggcaagca actgctggtc aatcagcttc tgaagccgag
    58441 aaattagcga aagcccaaga atatgtttct caacaatctg aaaatgcgga gaaaacgata
    58501 gatatcctaa gacgacagtt agaagctaca cagtctgaat ttggcgctac atccacagaa
    58561 gcaatgcaga tggaagcgaa gcttaatgat gctgaacgtg aatttgaaga gttaggacaa
    58621 gctgctaaaa atgtagatac aactaacttg gacgatatcg gaagcaaaat agatatgaat
    58681 aatttaatgg aagcttctga cgttttaagc gacattggcg ataagcttac agaattaggg
    58741 aaacaagcag tggactctgc taacagtgta ggtagttccc agagtaagat acaagctaat
    58801 tttggtttgt ctaaacaaga ggctgaagaa ttaacgaatg tagccagaga catttattat
    58861 aaaggttttg gagaatcgtt agatcagtcc acagatgcat tgattttggt aaagcgtaat
    58921 ttaggagatt taaataatca agatttacaa aatatcacgg aacaagctat ggtcctagaa
    58981 aacaccatgg gcgctgatat ggatgaaacg ttacgtggtg taaatggctt aatggtcaat
    59041 ttcggcttga gtgctcaaga tgcaatggat ttaatggttt cgggtactca aaacggttta
    59101 gataaaacgc acgaattagg cgacaatatg gcagaatata gccaattatg gagtcaaatg
    59161 ggatattcag ctgatgaaac gttcggaatg cttcaaaatg gtttagatgc gggtgcttat
    59221 aaccttgata aagtcaatga cttagttaag gaaatgggaa tatcgttaac agatggtcga
    59281 tttgagcaaa acatggatat gtttagtgaa agtactagaa aagcttttga agagtggaaa
    59341 aatggcggag gaacacaaaa agacgttatt aattccatga ttcaagattt tagcaatatg
    59401 gatggtcaat acgaccaatt aaataaagct tcgacaattt ggtctgcgct tggcgaagat
    59461 aatgcgatga aagttgtcca atctttaact gatgttaacc atacatttga tgatgttagt
    59521 ggatctgcac aaaaaatgaa tgaagattct actactccgt tgcaagagtt gaacgggaaa
    59581 atagctgaat taaaggattc attagctcct ataggcaaca caatcataga tgcactcgaa
    59641 ccagtaattg attttctagg aaagatggct gatgcgttta ataatcttcc acaaccagta
    59701 caggatttca ttgttgctat aggtggtctt acagcagcat ttggcatact gttaccggca
    59761 atactagccg tgtcatattt atttggtccg atgatgctta taattggagg aattatagct
    59821 gttatagcag gcgttattgt ggcaattaag aactggggtg caattactga ctggtttagt
    59881 ggtttatgga aaaaatttac tgattggttg ggtgatactt gggaaagtat aaaagacgga
    59941 gcctcatcag tttgggatgg ggttaaagaa acctggtctg gatttgtaga ttgggttcaa
    60001 gatatttggc aaggagtttc tgattggttt ggagagctat ggagcggatt agttgaagga
    60061 gcttccaaca tctggcaagg agtccaagaa acttggcaaa cattcgttga ttgggtttca
    60121 aatatttgga acggagtcaa agaagtatgg tcgattattt gggcagacat tgtaggaatt
    60181 gttcaaatac catggacatt aataacgtca ttgattcaag ctggtattaa tattatcgtg
    60241 ggtatttttg atgtagctgg acagttattg ggcgcagctt ggcaagctgt ttggacacct
    60301 atttctgatt tccttaaaaa tacttgggat actatgacac aatggataag tatcgcttgg
    60361 aatgggattg taactacatt ccatactata tttgatccag tagtggcatg gtggaatggt
    60421 atatggacag ctattagtac tacggcttca aatatttgga attcaattag tgcaacagct
    60481 tctagtattt ggaacagtat caagaataca atcactagct tggtacaagc agctgctaca
    60541 gtaattcaaa atatttggtc aactgtatct agttggttag gtggaatttg gaattcaatc
    60601 agctctacag catcaaatat ctggaatagt gtgactagta gtataagcaa tgctataaac
    60661 gcagctaaaa gtgccattca aagtgtttgg aatagtatat cttcgtggat tagcggaatt
    60721 tggaacggta tcaaaaatac tgctttgaat ctttggaatg gaattacaag cactattagc
    60781 tctaaagtaa acgatggaaa aaatgcaatt tcaagcggtt ggtccaatct aacaggtatt
    60841 gtttccgaca tattcaataa tgttaaaagt acaattgcta acatatggga aggcaccaaa
    60901 aagactgtta gcgctccaat tgattggatt agagacaaaa tcagtggcat ttttgataat
    60961 ttgaatattt ctataccaca tattccgtta ccggaattta tcatggaagg cagctttaac
    61021 ccgctaaaag gtcaaatccc ccatttgcgt gtaaaatggc atgctaaagg aggtatcttt
    61081 actaaaccaa ctttactagg tggaatgaac ggtgtcggtg aagcaggacc tgaagcagtt
    61141 ttacctttga aaagatctgt tttgcaagaa attggtgatc gtatcttgag tagcacatca
    61201 gtttcatcta gggcacaaac gattcaacct gtgaataact acgaattcaa tttcacaatt
    61261 gatggtaacg cagatgaggt tactatgaag caaacaactc aacaaatcat tgatagcatt
    61321 acaaaaattc aaaatgataa tgcttcggca tggcgttaaa caggagagta tttctcctgt
    61381 ttttttagta ttaaaaagga tgtgaaaaaa tgactgattg tatacattct ataatcgatg
    61441 gatttcctga ttatttgcat aaattggctt tagctgaaag accaaccata ccttctccaa
    61501 aaagacagag agttgaaact tctgttttag gtaggttagg tggcttagta caagattact
    61561 cgtttgaaga tatgtcgttt acattgcact ataactattt agaggatgtg gaagaccatc
    61621 aagcgttcaa gcaatcgttt tatatcatgc gtcattggtt aaactatgca aagaaattag
    61681 aattctctga cgatcccaac gtctattacg ttatccagac tatcgatatt ggggatgcag
    61741 aaaacgatat tgttgaatgg ggagagttcg atgtaaatat tactgcgaaa ccattcgcaa
    61801 gagttcaaga agatgtacct ataaccgtag ataaaccaca gtcatttaac ttgctgaata
    61861 atagtttaga agaaagtttt ccaaagatta tcatcactcc ttcagctact tcatgccagt
    61921 tcatcttaaa tgattatgtg tttagtttcg aaggcttagt agcaggaact gatgtagtca
    61981 ttgatagtga tttgatgctt tgctacgaag agcaatcgga cggagatatt ttagatcggt
    62041 ccaacaaaat gaagaccatg caatatccga cattgcaagt ggatatcaat cattttaatt
    62101 gcactggttt gagcaaaata caaatttatc gtaacgggtt aaggtaggtg aaatagatga
    62161 tcgataattt aataactatt tacgataaaa atgacgcgaa taatttagct gaacatttat
    62221 atgatacgca aggtttaggc gctttgtcag actggttaac agctactgtt agcaataaac
    62281 taaacggagc cgagatattt cagggtactt attcaataaa cggaactaat gcagatttga
    62341 ttgtagacgg acgtattatt cagtgttatg tagatgaaaa tcgagcaaaa cagcgtctac
    62401 ggatttatta tgcaaaaact tctgtaatag gcaatacgat agaagtaaaa gctgaaccta
    62461 ttttcaatga tataagaaaa tcggtgttga ataaatatga cagcggaaca gaaaagatca
    62521 ctgctactca ggcatggcaa aacgcaaaag ttttagcgaa accagctatc ccttcgcagt
    62581 tttctttctc gtcattagta gatacgcttg ctaatgtgaa gatagaaaag gcgaattttt
    62641 tagaattctt tggtggaaaa gagggatcta ttctagatcg atttcatggt gagtttctaa
    62701 aagataataa cacattacgt catgaaaaaa gtctaggtac ggatcataaa atcaaagcga
    62761 tttatactaa aaacttaact ggtcttgact tagagattga tgctcaaagt gttttagttg
    62821 gagtttatcc attcattagc agctcttcag aaggagaaga cgagatcact ctaccagaag
    62881 aagttatttt cacggattac gtggatgatt atcctgctgg atatgtttct tttgttgatt
    62941 ttaaagacaa agcgactgat gtagccacat taagggaagc tgctaaagac tggttgaaaa
    63001 caaacataga taaacaaaaa ccacaagtga gtggttcgat tgaattagta ccattgaggc
    63061 atcaaagagg ctatgaaaaa tttgttgatc tagaaaaagt ttcgatgggt gacggagtag
    63121 atgtgtatca tccacagtta aaagtgaata tgtcagcgag aattgtggaa tatacgttta
    63181 atgttctaac caattcatac gataaattag ttgtaggaaa cgtcaaaaca aacttcttag
    63241 aaaacacaga gaataatgtc agcaatttga ttaatgatgc cattgatcaa ttgaaaaacg
    63301 gtggcgaaat cagtgattta ctcaatgata ttgtagatca tcaaactgat atgattactg
    63361 gtcaaaatgg tggttatgtt ttattagatc ctaaagaagc gcctagtcgt attttgatta
    63421 tggacacacc agataagaat accgcaagga atgttttaca aatcaacaat gctggtattg
    63481 gtttttctaa aactggcatt aatggaacat atgaaacggc atggacgtta gatggcggat
    63541 tcaatgcctc gtttattacg gctggtgaaa tagtaggaat tactattaga ggtactacat
    63601 taattagtga tggtgctgat tatagaacaa gtattgctaa tggcaaaatg acttggtact
    63661 caaaaaaagt taacaaagat attatggagc tagaagcacg tgattatgta agtgctgatg
    63721 ccggtattgt atcatacacc atgaaaactg gtggtggttt catgattaga aatccacagg
    63781 gtaacttggt ttttagtacg tgggataatg gtaataacag accgtttcta tcttttggtg
    63841 cgcccaattt caggtatagc aatgctagtt atgtaacttc tggcgacggt agttctttaa
    63901 gcattaatgg tagtgcgggt aactcatggg aatttaaggt agctggtagg actatgaaat
    63961 ttactagtga tggtatgcta acgttaccag gttgtttttt ttgttcatgg gaagatggga
    64021 aacttgctag gtttgaacaa tcaacggtac aagtatataa agattttact gttagaggta
    64081 ctaaaaactc aactgtacca acagaacatt atggacaacg actattgaac gcttatgaaa
    64141 ctccagaata ttatttcgct gattatgggg aagccgttac aggtgacaat ggtaaagttc
    64201 gtgttgatat tgaccccatg tttgctgaaa cagtaaatct aagtcggtat atgacacatg
    64261 tgacacctac agaactagtt ttgtgtgctg ttactcatga agatattgac catttcatca
    64321 ttgaaactag taagccaaac gtattagtta gatggaattt agtggcacac cgtctagggt
    64381 atgaagatat tagattaaaa gaggatacag catatgatag cacagtgctt gaccaaaaac
    64441 gtttttaaaa cgaagacaag gaggtatata aatggctagc agtttatata atttggcttt
    64501 agatttcagc aaagaattaa actacaccaa agctattatg gctcgtcaag gtgataaagg
    64561 gattacggtg acggttaaac cgtttctaaa tggcttgcag atggatacga gtggcggaac
    64621 atttacttta aaaggaacaa caccatctaa ccgttacgta gataatgttg caactagtgt
    64681 aactagtgaa gaagtcacgt tttctcttga tggcacattt atgagtgaag caggatatta
    64741 taaacactgc tacgtagaat atagaaaaga caatcaaatt ttaacaacgc aagatatcat
    64801 ttttttctca ctaggagtgt ctgacatttc gcaaggccaa gccgatgaat atgtttcgca
    64861 attagaagag ttgattcgaa agtacaacga aacttttgat gcttttatgg ctgaaatcaa
    64921 aggtagagtg gatagcttaa atcaacagat tactgattta actggtcaag ctaaaacgct
    64981 acaagacaag ttagatgctc tgaaagaaga aatttctaag ttaggtaact tacaagtgat
    65041 gtacagtaac agcatcgact tcggggacta tgattattcg gagaacccga atttaatgcc
    65101 atatattaca gaaccttggg ttggaccttt gttaggtaat ggacatacag ttaaagatag
    65161 tgttaaaagg gttataactc atactaaaac tagaacagct aattccggcg acatattatc
    65221 gcttggctta ggtattccgt gtacagcgga agctaataat aggtatctta taaccacttt
    65281 acgaccatct acgacataca cattaagcgt tactatgagt gtcggttcag attggactgg
    65341 agagaccaat actatagggg ttaggcttag atatttaaat gaacaaggtg gtatagaact
    65401 gcccattaat gcattaatac cagcaaatgt agaacgcgat aaaatggtca ctcatacatt
    65461 tactggtata acaaaagata atgtaactag cataacaaac tgttatgttg aaatattctc
    65521 acttaatagt gaatataaag gaacggttag tgtcagctat gacgttaagt taaaagcaca
    65581 ctaccctaac ttactagatg gcccttactg gttaggtaaa gttcctttag gcgagaatat
    65641 tgctgaccct acagttgtct ttccacacaa aactagtgaa tatatggttt atggtagacg
    65701 caatacagaa aactatatcg ctgaccaaac atataccata tcaatgaaag caactaaact
    65761 aacagttcaa tcgtttgccg tgtatattgc tgctggccgc gttaaagtag gagacatgaa
    65821 gcctactgag gggttagcta atacatggga gttaactttt actgtaacta agcaacatat
    65881 agatagtggg gtaactaatt atctggaaat ataccaatac ccgtcagcta caaaaggagc
    65941 tgttcaaatt gagtggctca aactagaaaa aggcaatact cgaaccccga atattagtga
    66001 gtataaatat cgtggtactg gtatgcgtga ttcaaacaat ccaaaagatt atgtttggga
    66061 tctagcacca gaatatgtcg aagataattt ggccacagat attaaaattt ctgaaattac
    66121 tggtaaagca aacaattata ccgatgggaa agtatcggag attaattcgc agttgactgc
    66181 ttcaattaat gaagtagaca ccacagctaa ggatgctcaa acaaaagcga atgctaatgc
    66241 gactgctata gatgaattag acaataagat cgatgaacgc attaatgata cagctactac
    66301 cacattaaca gttacaaacg ggaataccgg atcagcaaag ctttatcgtg aaggaaaaac
    66361 agtttctata tattttgtgg ctttaaacgg aaaaagcagt ggtggaaatg attcaacgat
    66421 actaacaatt ccagaaggct atcggccacc aattagtttt gagcaactgg ttggctcgat
    66481 agaccgttct actttgaaca gtgctcagtt atctattggt gcagatggag ccattaaatg
    66541 gcgaagaaac tcaagttatg gatcggatta tacctttgca attacttaca cgatttagaa
    66601 aagcgtgaat cgatatgaag gcagcatata gaccaattga accttacgga ttcgagcaaa
    66661 tcattgtgaa tgatgaagaa catttaccgg aagaatgcac agaagtcgaa ccaccgattc
    66721 caaattggaa accgaaattc aattactggg agggaaataa atgaaaaaca tttggaaata
    66781 tggacgtact ggcggagagt acgcaggaaa agtattggac gacatgcttg tatccgttcc
    66841 ttacacagat cagccaccgc ttgaaggaat tcgtgctgat ggcgaaccgt taacaatcgc
    66901 tgatcaaatg tttgatccta aattgaatca atggattatt ttagcgaacg cactagatca
    66961 caacgattta aacaatctca aagcaatgta tgagtcgtta gaaaatgaga acggcgattt
    67021 aaaacagatc aatgccaaac tcatgctaag cgatgtagca attaaacagg aaaatactgc
    67081 attgaaagaa aaagcggata gtttagcaca aatcaattca aaaatgatgc ttgcttcgtt
    67141 acaaaatagc aaagacattt cagaaattaa agagcaacta aatccagctt caaagggagg
    67201 tgagtagtat gtttagtttt agcgatgtga aaatgatgta tgattggggc tgtttcacta
    67261 acgaacaagt aatggttttc gttccgttgt gcattactga agaaaaagca gataaaatca
    67321 ttagcaaaga agagagcgca tcttaattga tgtgcttttt attttgattc aaggagttgt
    67381 cacatgatta atttagggga atggggagcg atagcaggat caataaccgc tatcgtttct
    67441 ttgattttat tagtaataaa accaattact gcatctttct cgaagattac tgagactctt
    67501 tcaaaagtaa gtcacaattt agatttgctg actaaagatt tagaatcgag caaatcagat
    67561 cgattgatga ttcatgaaga actaaagaaa cacgatgaaa gattagatac acatgcagaa
    67621 aaattggtag aacacacgca acaaattaaa actttattta gggagagaag aaaatgaata
    67681 ataaaacgtt cgaagtacta aaatggttcg cactggtaat tattcccgca ctagctactt
    67741 tcgtggggtt agttggtaaa gcgctcaatt ggcagtacac agatatctgt gttgtcatca
    67801 ttactggttt tggcgcgttt ttagggagtg tgttgggtgt atcaaatcga acctacaaaa
    67861 tgttctcggc tgaaagcgaa gaaggaggaa acaaatgaaa aagaaaatta ctattactgc
    67921 gatgagcctg ttaacggctc tttttttatt acccattaat acgtttgctt atactattaa
    67981 tgacgagtat aatttagcgc cgaatcaagg agactccaga ttagcaattc ctaacaaaat
    68041 tattttgcac gaaactggaa tagatgcacc agcaagaaac gtagccgcca acatgaaaaa
    68101 taattataac ggaagcaatt cttatactac agatgttatt ggtgacggtg ggattgttta
    68161 ccgtgtgggt gagcaaggat atgtttcgtg gggagctggt aacgctaatc cttatgcgcc
    68221 tgtacagatt gaattacagc gcacatatga taaagcattg tttgaaaaaa actatcgagc
    68281 ttatattgaa tatacaagag atagtgcaaa aaaatatgga attccattga ctcttgatca
    68341 aggaacttct ttatttacaa aaggaatcat ttctcatttg tgggtgacaa attatgtttg
    68401 ggggaaccac acagatccat atggttactt atcgcaaatg ggagttagca aagaaaagct
    68461 tgcttatgat ttagctcatg gatttaccga tgaaaatcca acaacttctg aaaacaagcc
    68521 tgtcattgat ccaacacgag ctggtgcagc taatcctacg ctgacagatg gaacaaatca
    68581 cgcccacatt gatcagtttg gggaaatcga aaacgcaaac ttgcatgtgg ctggatggca
    68641 cattgctaac tataaatacg agtatatttt cattatggac tacaatactg ggaaagaatt
    68701 agctcgagta agagctgatg gaatttatag accagatgta aaccaagctt ataatacttc
    68761 tggaaatgtt ggttatcatg tatctttcaa tatgcgtaat tttcctagta agaaagtcta
    68821 tgtaatgatg cgggcaacga atgatccaga gggaaacact aaaggcggtg cgcaagattt
    68881 ccatgacaaa cgttggtatt taaatattcc taaacgataa aaatagctcc tcgttgagga
    68941 gcagtacata actatattga caactataaa aattattcga taaaatagtg atgttatcgc
    69001 atatcttcac tatcacccat aaatagtcac actccaagct atgcgataac aggtttgttg
    69061 ccacacattc tactggttga ttgtttatgg ctttatgtgg caacaaccag tacccttagc
    69121 tcagttggtc agagcagacg gctcataacc gtccggtcgt aggttcgagt cctacagggt
    69181 acattaacgt agccatttga atcgttctgt gttagaattt ttttgaagag tattatacaa
    69241 gctaaagctt ttcttcattg ccactcaaat gagtggcttt tttatgtatc cttttatgga
    69301 ttaatgaaag gatgtttcac atagttatac ttctgtatat ttgaaaagtt ttactttgat
    69361 ttttaaatag aaagacattt gggttaaatt gtgagataat aataaagaag agtttaaagc
    69421 gcaccccaaa ccacttcccc ataagtgtgt tacgctttaa actcttttat atttgaagcc
    69481 attaaaaagc ataccatatt tttgaaaaaa agtgagaaaa aaggcttaca attggagtgg
    69541 tagttaatta gtgacttatt tttgatttta tagcactgat actataaaat atagatatca
    69601 tcatattaca caatcttaat actaacttaa aaaatatctc ctttcacaag tatggtgata
    69661 aaattcgttc cgggctacct ttttaggtag cctactttaa tctttatacc tttctggatc
    69721 aacgaaagta tactttatat agtcataacg ccgatgatcg ctacgtgcgt ccggcacgtc
    69781 agtc
//
LOCUS       DAZKCW010000008        67741 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000008 DAZKCW010000000
VERSION     DAZKCW010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 67741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.008"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(114..659)
                     /locus_tag="ACG84Z_000576"
     CDS             complement(114..659)
                     /locus_tag="ACG84Z_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFP9161446.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(671..1363)
                     /locus_tag="ACG84Z_000577"
     CDS             complement(671..1363)
                     /locus_tag="ACG84Z_000577"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFP9161447.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1382..1666)
                     /gene="macP"
                     /locus_tag="ACG84Z_000578"
     CDS             complement(1382..1666)
                     /gene="macP"
                     /locus_tag="ACG84Z_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFP9161448.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1679..2242)
                     /locus_tag="ACG84Z_000579"
     CDS             complement(1679..2242)
                     /locus_tag="ACG84Z_000579"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFP9161449.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2470..3132
                     /locus_tag="ACG84Z_000580"
     CDS             2470..3132
                     /locus_tag="ACG84Z_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFP9161450.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3256..4452
                     /locus_tag="ACG84Z_000581"
     CDS             3256..4452
                     /locus_tag="ACG84Z_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFP9161451.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4553..5929)
                     /locus_tag="ACG84Z_000582"
     CDS             complement(4553..5929)
                     /locus_tag="ACG84Z_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9161452.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5966..6832)
                     /locus_tag="ACG84Z_000583"
     CDS             complement(5966..6832)
                     /locus_tag="ACG84Z_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFP9161453.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6921..7946)
                     /locus_tag="ACG84Z_000584"
     CDS             complement(6921..7946)
                     /locus_tag="ACG84Z_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9161454.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7964..8638)
                     /locus_tag="ACG84Z_000585"
     CDS             complement(7964..8638)
                     /locus_tag="ACG84Z_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9161455.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8822..9715)
                     /locus_tag="ACG84Z_000586"
     CDS             complement(8822..9715)
                     /locus_tag="ACG84Z_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9161456.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9789..11486)
                     /locus_tag="ACG84Z_000587"
     CDS             complement(9789..11486)
                     /locus_tag="ACG84Z_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFP9161457.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11479..12792)
                     /locus_tag="ACG84Z_000588"
     CDS             complement(11479..12792)
                     /locus_tag="ACG84Z_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFP9161458.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12792..16733)
                     /locus_tag="ACG84Z_000589"
     CDS             complement(12792..16733)
                     /locus_tag="ACG84Z_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFP9161459.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16842..17300)
                     /locus_tag="ACG84Z_000590"
     CDS             complement(16842..17300)
                     /locus_tag="ACG84Z_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9161460.1"
                     /translation="MKGLKLKILQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(17598..18116)
                     /locus_tag="ACG84Z_000591"
     CDS             complement(17598..18116)
                     /locus_tag="ACG84Z_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFP9161461.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(18118..18735)
                     /locus_tag="ACG84Z_000592"
     CDS             complement(18118..18735)
                     /locus_tag="ACG84Z_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFP9161462.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(18732..19520)
                     /locus_tag="ACG84Z_000593"
     CDS             complement(18732..19520)
                     /locus_tag="ACG84Z_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9161463.1"
                     /translation="MTVIGIILIIPLLWMVFTSLKPMEEIVRYPPTFFPEKIVWENYL
                     DTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYGFAKLDFPGKKLMFALVLSTMMI
                     PGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFNIFLMRQFYLSINNELIEAAEID
                     GANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFLGPLLYIQDQEKYTLQIGLQVFQ
                     NQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGMDLTGGSKG"
     gene            complement(19582..20493)
                     /locus_tag="ACG84Z_000594"
     CDS             complement(19582..20493)
                     /locus_tag="ACG84Z_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9161464.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(20534..21868)
                     /locus_tag="ACG84Z_000595"
     CDS             complement(20534..21868)
                     /locus_tag="ACG84Z_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9161465.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            22076..22906
                     /locus_tag="ACG84Z_000596"
     CDS             22076..22906
                     /locus_tag="ACG84Z_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFP9161466.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(23150..23399)
                     /locus_tag="ACG84Z_000597"
                     /pseudo
     CDS             complement(23150..23399)
                     /locus_tag="ACG84Z_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23590..23784)
                     /locus_tag="ACG84Z_000598"
     CDS             complement(23590..23784)
                     /locus_tag="ACG84Z_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161467.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(24289..24474)
                     /locus_tag="ACG84Z_000599"
     CDS             complement(24289..24474)
                     /locus_tag="ACG84Z_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161468.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(25324..25665)
                     /locus_tag="ACG84Z_000600"
     CDS             complement(25324..25665)
                     /locus_tag="ACG84Z_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFP9161469.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(25665..25895)
                     /locus_tag="ACG84Z_000601"
     CDS             complement(25665..25895)
                     /locus_tag="ACG84Z_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFP9161470.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            26182..26520
                     /locus_tag="ACG84Z_000602"
     CDS             26182..26520
                     /locus_tag="ACG84Z_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161471.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(26725..27287)
                     /locus_tag="ACG84Z_000603"
                     /pseudo
     CDS             complement(26725..27287)
                     /locus_tag="ACG84Z_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(28019..28600)
                     /locus_tag="ACG84Z_000604"
     CDS             complement(28019..28600)
                     /locus_tag="ACG84Z_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9161472.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(28783..29409)
                     /locus_tag="ACG84Z_000605"
     CDS             complement(28783..29409)
                     /locus_tag="ACG84Z_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFP9161473.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(29431..30762)
                     /locus_tag="ACG84Z_000606"
     CDS             complement(29431..30762)
                     /locus_tag="ACG84Z_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFP9161474.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(30917..31318)
                     /locus_tag="ACG84Z_000607"
     CDS             complement(30917..31318)
                     /locus_tag="ACG84Z_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFP9161475.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(31404..31610)
                     /locus_tag="ACG84Z_000608"
     CDS             complement(31404..31610)
                     /locus_tag="ACG84Z_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161476.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(31705..33207)
                     /locus_tag="ACG84Z_000609"
     CDS             complement(31705..33207)
                     /locus_tag="ACG84Z_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFP9161477.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(33225..33680)
                     /gene="argR"
                     /locus_tag="ACG84Z_000610"
     CDS             complement(33225..33680)
                     /gene="argR"
                     /locus_tag="ACG84Z_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFP9161478.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(33778..34395)
                     /locus_tag="ACG84Z_000611"
     CDS             complement(33778..34395)
                     /locus_tag="ACG84Z_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFP9161479.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            34616..35989
                     /locus_tag="ACG84Z_000612"
     CDS             34616..35989
                     /locus_tag="ACG84Z_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9161480.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            36064..37176
                     /locus_tag="ACG84Z_000613"
     CDS             36064..37176
                     /locus_tag="ACG84Z_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFP9161481.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(37248..38885)
                     /locus_tag="ACG84Z_000614"
     CDS             complement(37248..38885)
                     /locus_tag="ACG84Z_000614"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFP9161482.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(39053..39661)
                     /locus_tag="ACG84Z_000615"
     CDS             complement(39053..39661)
                     /locus_tag="ACG84Z_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFP9161483.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(40045..41196)
                     /gene="queG"
                     /locus_tag="ACG84Z_000616"
     CDS             complement(40045..41196)
                     /gene="queG"
                     /locus_tag="ACG84Z_000616"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFP9161484.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(41215..41967)
                     /locus_tag="ACG84Z_000617"
     CDS             complement(41215..41967)
                     /locus_tag="ACG84Z_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161485.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(42108..43058)
                     /locus_tag="ACG84Z_000618"
     CDS             complement(42108..43058)
                     /locus_tag="ACG84Z_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFP9161486.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(43059..43898)
                     /locus_tag="ACG84Z_000619"
     CDS             complement(43059..43898)
                     /locus_tag="ACG84Z_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFP9161487.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(43895..44641)
                     /locus_tag="ACG84Z_000620"
     CDS             complement(43895..44641)
                     /locus_tag="ACG84Z_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFP9161488.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            44879..46249
                     /locus_tag="ACG84Z_000621"
     CDS             44879..46249
                     /locus_tag="ACG84Z_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9161489.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(46304..47200)
                     /locus_tag="ACG84Z_000622"
     CDS             complement(46304..47200)
                     /locus_tag="ACG84Z_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFP9161490.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(47314..47484)
                     /locus_tag="ACG84Z_000623"
     CDS             complement(47314..47484)
                     /locus_tag="ACG84Z_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161491.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(47481..48158)
                     /locus_tag="ACG84Z_000624"
     CDS             complement(47481..48158)
                     /locus_tag="ACG84Z_000624"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFP9161492.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(48249..49154)
                     /locus_tag="ACG84Z_000625"
     CDS             complement(48249..49154)
                     /locus_tag="ACG84Z_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFP9161493.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            49329..50783
                     /locus_tag="ACG84Z_000626"
     CDS             49329..50783
                     /locus_tag="ACG84Z_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFP9161494.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            50799..51830
                     /locus_tag="ACG84Z_000627"
     CDS             50799..51830
                     /locus_tag="ACG84Z_000627"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFP9161495.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            51837..53024
                     /locus_tag="ACG84Z_000628"
     CDS             51837..53024
                     /locus_tag="ACG84Z_000628"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFP9161496.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            53180..54562
                     /locus_tag="ACG84Z_000629"
     CDS             53180..54562
                     /locus_tag="ACG84Z_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFP9161497.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            54599..54919
                     /locus_tag="ACG84Z_000630"
     CDS             54599..54919
                     /locus_tag="ACG84Z_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161498.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(55119..55787)
                     /locus_tag="ACG84Z_000631"
     CDS             complement(55119..55787)
                     /locus_tag="ACG84Z_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFP9161499.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(55976..56773)
                     /locus_tag="ACG84Z_000632"
                     /pseudo
     CDS             complement(55976..56773)
                     /locus_tag="ACG84Z_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(57054..58433)
                     /locus_tag="ACG84Z_000633"
     CDS             complement(57054..58433)
                     /locus_tag="ACG84Z_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFP9161500.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(58608..59777)
                     /locus_tag="ACG84Z_000634"
     CDS             complement(58608..59777)
                     /locus_tag="ACG84Z_000634"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFP9161501.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(59752..60903)
                     /locus_tag="ACG84Z_000635"
     CDS             complement(59752..60903)
                     /locus_tag="ACG84Z_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFP9161502.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(60863..62224)
                     /locus_tag="ACG84Z_000636"
     CDS             complement(60863..62224)
                     /locus_tag="ACG84Z_000636"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFP9161503.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(62221..63222)
                     /locus_tag="ACG84Z_000637"
     CDS             complement(62221..63222)
                     /locus_tag="ACG84Z_000637"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFP9161504.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(63238..63933)
                     /gene="dapD"
                     /locus_tag="ACG84Z_000638"
     CDS             complement(63238..63933)
                     /gene="dapD"
                     /locus_tag="ACG84Z_000638"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFP9161505.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(63939..64655)
                     /gene="dapB"
                     /locus_tag="ACG84Z_000639"
     CDS             complement(63939..64655)
                     /gene="dapB"
                     /locus_tag="ACG84Z_000639"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFP9161506.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(64652..65533)
                     /gene="dapA"
                     /locus_tag="ACG84Z_000640"
     CDS             complement(64652..65533)
                     /gene="dapA"
                     /locus_tag="ACG84Z_000640"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFP9161507.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(65536..66336)
                     /gene="dapF"
                     /locus_tag="ACG84Z_000641"
     CDS             complement(65536..66336)
                     /gene="dapF"
                     /locus_tag="ACG84Z_000641"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFP9161508.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(66323..67582)
                     /gene="lysA"
                     /locus_tag="ACG84Z_000642"
     CDS             complement(66323..67582)
                     /gene="lysA"
                     /locus_tag="ACG84Z_000642"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFP9161509.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
BASE COUNT        19289 a        14302 c        11967 g        22183 t
ORIGIN      
        1 agaataagtt tttttaaaat aacgtataaa aaagagcata aaacaaagtc gtttgtttta
       61 tgctcttctt ttattatttt gtgcttttta ttttatcaaa tcactttgtt tttttataaa
      121 atttctgcgc ctagtgtgga ctcaaaatgt ctcaatgccc attcatgtcc aacgggatcg
      181 aaacttgcca cggaatcttt gaaaatatgg agtttgtatc ctagattata cgcatcgact
      241 gctgtatgca acacacagat atctgtacat acgccggtca aataaatatc tgtgatctgg
      301 cgttctcgca aacggatgtc tagatctgtt ccactaaaag cggaataatg ccgtttgtct
      361 atccaataaa cattttcctc ttgctcatag tcttggtata aactttttaa agagccgtac
      421 aattcccgtc cacccgttcc tatcacatta tgcggaggaa ataagcggtt ctccggatga
      481 aaggaatctt ttggatcatg cgcatcaatg gcaaaaacga caaaatcctt ttgatcaata
      541 aacttctttg tatgagcagt cagctttttt tcaattactt gtcctgctgt cccagtagtc
      601 agctttccat cctctgcaac aaaatcatat gtgtagtcaa tcgagatcaa tgcgttcatc
      661 ttagtcctcc ttatacgaga tgtttgacaa attcgatcac catttctgct gatcgtttgc
      721 ctgcgtcttc gataaattcg tcaaagcttt gtgtcgccga gtgatctgct gtgtcgctca
      781 ttgcacgtac gatcaaaaat gggatattga actgacgagc tgtttgtcca acagcggctc
      841 cttccatttc gcaagctaat gcttcaggga aattcgttaa gatttctttg attttatctg
      901 gcgagtcgac aaatgtatca cctgtaacga tcaatccttc ttttgcgttc aaattcgttg
      961 cttttgctgc tttaaccatt tcactgcgca aatatgtgct tgcttcataa tatagaggca
     1021 ttcctggtaa ttgtcctggg ttgtagccaa atcctgttgc atctgcatca aaataagcta
     1081 ctttgtctga tataacgatg tcacctactt gtaagccttc accgattccg ccagctgaac
     1141 ctgtattgat caccatgttc acgccgtatt gttggatcaa cagacttgtg gtaatagatg
     1201 ctaagacttt tcctataccg gaacgtacga cgatcacttc gtggttacct aatgaacctg
     1261 aaataaataa agcgcctgcg cgttcccatg ataatggttc gcttaggttc tctctcaaaa
     1321 tttttacttc ttcttccatt gcgccgataa taccgatttt catcttttta attccttctt
     1381 tctatataaa tgcgattgct aaaaaaacca cacataacat taggataaca ataataagag
     1441 atttcatcaa aaaagagttc catttggtcg tcttttcccg ttcgctgatc cttgttttcg
     1501 tgattggttt attctttttg ctttctttac gataaaagct ggcaatcttt ttttcttctt
     1561 gctgataagc tgtttctgct tttcgctgtt tttttaatga ctcgcttgct tgtgcttgtt
     1621 gtcgcttgcg aagttcgctt cgcgtaataa gcggtccttt ggccataagc cgatccctct
     1681 actttccttt ggtcaatagt tcccagtatt gaatcgcata aatcgtcttt gcatcacaaa
     1741 tcaactgatc tttcatcgct tgttgcgcct cttcaagagt tagatgatac aactccagta
     1801 cttcgtcttc atcttgtgct aaaggattct cgaccttctc taccccttgt gcatgataaa
     1861 tatgaaggac ttcatttgca aaacctggtg aaagatacat cgaagtaaga tggctcagcg
     1921 acttcgcacg atagccagtt tcttcttcta attctctagc tgctgtcatt tcgggatttt
     1981 gtccttctcc tggatcgatt tttccagctg gaatctccaa aatcactttt tctaaaggtt
     2041 ttcgaaattg tttgacaaga agcagacgat cttgttcgtc aaaagcaatg atcccgacac
     2101 cgccaggatg aaataccagt tctctcttcg aagttcctcc atctggcaaa cgaacttcgt
     2161 ctacagcaac atcaataatt tttccgctat agatttcttt gcgactgatt gttttttctt
     2221 caaattgctc attgttcagc atatcttctc ctgctttctt tgtaatcata actgcttttt
     2281 tttcattttt caatttttct caaaaactcc ttattagttt accatagata aaccttagat
     2341 tttctctaaa tatagaaaat ccttctttag tccgatactc tttctagtag tccgtatgct
     2401 aaaataagta tgtaatcgaa taacgaaaag aattcaatac tcaacgataa atgacatgga
     2461 gggtttatta tgataaaacg aaattggccg tggcttctag cattggtctt gctatttctc
     2521 tttgtccgaa acaatagttt ttcttttgtt ctaggacttt tattgatagg tgtagtttta
     2581 gttttgtggg gactctttgg ttcgcgcagg aaaaagggaa aacaagaaga aattcctgca
     2641 ctgactgacg aacttgaaac tcactatgaa aaaagcggta tgacagcgaa tgaaatttca
     2701 ttttttcgac aaacaatgaa tcaaacaaaa aatgagatca atcaattgca aatgaatatg
     2761 cagcagacag ccaaacttaa agcaatcgat ctccgccatg atccagtcaa agcagcgaaa
     2821 gctttattca aagaattggt gaaagaacca aaccgactgc atgaagcaag tcagtttctt
     2881 tatacgcatc tgccgaatct agttgatttg acaaataagt ataatgagat caatgaccat
     2941 gagatcaaaa acaaacagac ctatgaaaaa ctagaagaaa gcgcgcagat catcgaccag
     3001 ctgtcagctt taatcgcaca agattatcaa aaattcgttg ctgaggatct agatgatatc
     3061 gacgtagaga tatctgttgc gaaacagagc ttaaagcgtg ataataaata tgaaccagaa
     3121 caaaaggatt aactcttttg ttcataaaag aagactcgga acattcagat gatgtctggc
     3181 tgtttcgagt actttttcta aagtagagac attcatgtaa gaatcgagaa cagattcaac
     3241 aaggaggaat tttttatgga tcataaaccg actgaaacaa aagatgttac accagttaac
     3301 gatacacttg aagatttatt gaacaacccg ttttcaactc caacagatac gctgaccact
     3361 tcacaacaag cggagattga tcagctccaa gagcaacaga cagctgctcg tttaattgac
     3421 aaactaccgg cggaacgcca agaacaagct aaacagctag cagcaaaaat cgatgctaat
     3481 gatgcacagt ctgtcatcag ctacggatcg gctgcccaag caaaattaag tgaattctca
     3541 caatcgatgt tgaatcatgt gcaagcacaa gatattggtc ctgtaggaga ttccttaact
     3601 gaactgatgt atcgtctcca agaagccaat cctgacgaac tgcgtgccgg agaagggaac
     3661 atcttccagc gtgtcttcgg gaaggtcaaa caatcgatct atgaagtgac agcaaaatat
     3721 caaaagattg gtgcacaaat tgacaagatt tcagtgaaat tagataaaga aaaagacggt
     3781 ctgctaaaag ataatctgat gttagaacag ctttaccaga aaaacaaaga ctactttgat
     3841 gcactgaata tttatatcgc tgctggagaa ttgaaaatgg aagaacttca aacaacgatc
     3901 attccagaag cgatgaaaag agcagaagaa actggcgatc agatggatgt tcagattgcc
     3961 aatgattaca cgcaattcct agatcgtctg gataaacgta cgcatgatct tcgcttagct
     4021 agacagatca cgatccagca agcaccacaa atccgtttga tccaaaacac aaatcaggcc
     4081 ttggctgaaa agatccaagc atctatcgct acagccattc cgctgtggaa aaaccaagtc
     4141 gtgatcgcat tgaccttgct tcgtcaaaaa gatgcagtaa ctgctcaacg ccaagtctct
     4201 gaaacaacaa acgacttatt gaagaaaaat tcagaaatgc tgaaaatctc agccatcgaa
     4261 acagcgaaag aaaatgaacg tggaatcgtg gatatcgaga cccttcaaac cactcaaaat
     4321 gatttgatcg aaacaatcca agagacattg cgtatccaaa aagaaggaaa agaaaaacgt
     4381 cgtcatgcag aagtagagct tggacacatg gaagaagatc tgaaacaaaa actgttggat
     4441 ttaacccaat agatcacctt tcgcttgtta ctaaaacaaa cgcccaacaa cagtttatta
     4501 caactgttga tgggcgtttt tcttatcttt cttctaactt ctccattgga gtctatttct
     4561 cattcatctt gctgtgtcca tagccatagc caaaataaat gatcagtcca ataaccatta
     4621 cgataccgaa cacgatccat gtcacagttt gcagacgaag catcaataca atacaagtca
     4681 agatggagac gattggcaat agcggaacga atggcacttt gaattctcca gcttttggtt
     4741 tgccaaacat ttttctcaac ttcagtaagc ctagactaac aagcatcaaa taggcgagcg
     4801 ccatgatatt cgttagttcc gctaatacat tcaatgggaa aaatccggca aagaatacag
     4861 ctgccacacc agcggcataa gtcgcttttt tcggtgtacg atgcttttga tcgatttctg
     4921 tcataaactt aggaagtaag ccatccttgc tgacagcaaa cagtaaacga gcaagtgaat
     4981 acatcatcga gatcgttacc gtcagtagcg ttaaaattgc ccctacagcg atcaccgcgc
     5041 ccactgttcc atgtcctaca tacctcattg caaaagccac tgggtcattg actcctagtt
     5101 cagtatacgg aacgattcct gtcaagatca gcgtcacgat gatgtaaagg acagtagcaa
     5161 tcagtatcga accaatgatt cctcttggca catctttttg cgggtttttg acttcctcgg
     5221 ctgccattgc aacggcatca aatcccaaga aagcaaaaaa cacaagagct gcaccatcta
     5281 gcacaccgga aaaaccaaaa ggcatgaatg gctgccagtt atcaggttta acgaaaaata
     5341 ttcctacaat gataaacaac gcgatgatac caaatttgac atataccatg gcattattca
     5401 aacgtaatgc tttcttggct tcaagcgaca cgatgtaagt gacgaatatc actacgagca
     5461 ccgcaatcaa gtcaatgtat gtaccatttt ccggattgta cccgccagtt aatgcttgtg
     5521 gaagttcggc ccctaaactt ttcaaaaaac cttgcatata gccagaccat ccggaagcaa
     5581 cagaggaaac cgctagtaaa aattccccga tcaacaacca ccctgtcagc caggcagcaa
     5641 attcaccaaa tacaacatac agataggcat atggcccacc aatcactggc actcgcgaag
     5701 caaattctgc gaaacttagt ccagacaaaa tgacaacgat tgcagctaag acaaatgaaa
     5761 gtgacagtgc tggaccagca ttttgattgg ccgcaacccc tgtcaccaca aatattcccg
     5821 taccgatgat cgcaccaatt ccaagcatga tcaaatcaga cgtttttagt tcttttttca
     5881 tctcactcgt atgattgaga ttgatctctt tcttacgaaa caaatccatt gaagttcctc
     5941 cccattttag gttggaaaac agcgattaaa ctgttttcat ataccctaaa aggataccac
     6001 ctaaaatgac taaaaggcaa ccaacaataa cataaatgag ctcttttttc gtttttcttt
     6061 cgccaaggat gaaaatccca cctaaagtag agataatgat ccccatttgt gaaagtgaga
     6121 agccaacagc taaaccaagt gatttgactg ttagaagcat gcagatgttt cctaagcccc
     6181 ataataatcc acagatcatg tttttccaca caaactgatc gactttaact ttacggaaag
     6241 caaagaagct tgcgcctaag atcattccga tactttgagg taagataatt gacatcgcat
     6301 ccaaattcgc ccagttgacg atgatggtat atacaccata accaatcgta gagaagatca
     6361 atgctctaaa acccttacca aaatcaagca ttttattatc tgtatctatt tttccttcgt
     6421 catcttgtcg ggcagtcaaa tacgcaccgc ttacaagaag agctaaagca ataataccgt
     6481 atacataatc tttcgtttgt gtccattcat ggaagaaaac ggctcccgca atcgtattca
     6541 aaattaattg aaaaccagta gacaatggta gccctacaga aacacccatg tacttcattc
     6601 catggaactg tccattttgt ccaacactcc aagctaagcc ggataaaaat ccgatcaaga
     6661 aaatccaagg ggtgattaca ggactaacaa cgaaaaagac aactaaagaa aacagaaatg
     6721 caccgatcgt cattcctagt gtttgttgat tggcatcgcc accaatttta ccacttacta
     6781 aaccaatact accccatgcc aacataggga ctaatgctat taaaatttcc ataaccaatc
     6841 tccttttatt tcacatgata agaaacttat cagcgaaaac gttaacaaca caagcacttt
     6901 ttttcgtttc taacgatttt ctaacgtttt tcattataaa aatttaagat tgggaaaaat
     6961 aaagtcattg ttgtcccttt tccttcagtt gattcagccg tcaaatggat acctaatttt
     7021 tcggccagat tttttgctaa ataaagtcct aatcctgttg aatgtgtttt gctaagtcga
     7081 ccatttctcc cagtaaatcc cttatcaaag atccgtttca agtcttccgc tgggataccg
     7141 atccctgaat ctttaactga aaggctgact ccttgcgctt ccttttctat gctcacaatg
     7201 atgtttccgt gatccggcgt atatttgatg gcattactaa gcaattggtt gaagataaaa
     7261 gcgatccatt tagcatcggt caaaacagta tgatcctcac caacgatctc gtagcgaata
     7321 tttttttgga taaaataatt tgcctgactg cgtatcacag gctgaatgat tccttttagt
     7381 ccatattctt ggatgaggta gtcccgcgag aaactgtcga gtcttgcata atacaaaact
     7441 tgttctacgt attcatcgat ttttgataat tcattttcta gtaatgtata cttttgatcg
     7501 tcaatatcga actcgatcga acgaactagc aatttagaag cggaaagtgg cactttgatt
     7561 tcatggaccc atgagtcaat ataatctttt tggtcttgtt gattactgat tgctgattgc
     7621 attacttctt ggtgttcacg gatcagctga ttgatatatt cttctaccag tttttcttct
     7681 tctgtcctcc caccactcaa ataattttgc aaaggggaag ttttttgtat gtcggctaat
     7741 tttccccacc atcttctctt gctcaagtaa ccacccagca gataaaaaat cagaaagacg
     7801 ccctcaatca aagctaaata agcaattgtg ctcaaatcaa ctttgatgtt tggcgccagc
     7861 cacatcacaa agatcgtcaa tgcaataaaa aacagccatc ccaagatcaa tgtccactga
     7921 tctttcaaat atttaaaaaa attcatctta accgctcatc ctttcaggga acgatatatc
     7981 cctgtcctac ttttgtttcg atatatcctt ggatacctgc ctgttcgatt tttcggcgta
     8041 accgattgat gttgactgtc aatgtattgt catctacaaa tcgttcgtca tcccacagtg
     8101 ctcgcagcaa tttttcccga cttaagatct ttccattgtg cttcatcaaa ataaataata
     8161 gacgatattc atttttgctc aaatcaatga tctctccgtt gatttccata cttccgttgt
     8221 caacattcaa cgtaatgcca ttgtggctca tcatttcact agataattct gtgtagttgt
     8281 aagaacggcg aagtaatgca ttgatttttg caatcagtac atcgatttgg aaatgttttg
     8341 tcacaaaatc atctgccccc atgttcatag ccatgatcat atccatattc gtattcctgc
     8401 tggagataaa aatgatcggt actttcgata cttcacgtat tttttgacac caataatagc
     8461 catccaaaac gggaagatta atatctagta atacaagctg tggttcttct ctttcaaagt
     8521 ctgagaacac ttgattgaaa tcggtcgttc caaaggtttc aaattgccat ttctcaagtt
     8581 cctccatgat caattgtcga atgatctctt cgtcttcgac taccatgatt tttgccataa
     8641 aaaatccctc catctttctt cttgctacta caatatcaaa gaagcccttg tgaaacaagt
     8701 tggcttacct ggaaaatgtc attttagcaa acgttaaaaa aaactggaaa tatgcgattt
     8761 aatcgcgttt gtctcttcca agcagcttaa atttattatg ttattcttaa taattggtct
     8821 attatctgtt atttttcttt cgttgttttt gtcttttaaa ttttcgataa caccaataac
     8881 cgaaaagcgt tagcactagc aatataccta gaaggagtat aagtaatcga taaagatggt
     8941 atttttttgt ctgttctatc tttgaagaga cttcttctgt aaagggaact cgtcttcctg
     9001 tcactagtaa tcggtgagtg ttcacggtgt aaggtgtaca agtgataagt gtgactagat
     9061 cctgcttttc tctaattgct aatgtatttg tttttgttgg aaggacaaca attttctcaa
     9121 cgacttcata agcgagcatc cgaccataca cttcaagata gaatcggtca tcttgctcca
     9181 tttcttcaag atccgtaaag agttttttct cagcaatacc gctatgggcg gtaatcacgg
     9241 aatgtgtact ctctcctcca gttggaaaag aggtgccttg caggactgtc gctcctctat
     9301 ctaacaaaag atcattcgtt tcatcaaata aaggcaagct aacattgatt ttcggaatat
     9361 agatggctcc gatcatatgt tgttcgtaat attcttttcc tggattttgg acatttctaa
     9421 ccgcttgctc aaaaggatct ttgacttgtc ccattcctgg gattactgat gtatgagcaa
     9481 gcgtctgatt tttcttttca tgcactgcta attgttgctc atgtttttct tctttatcgc
     9541 gttcaagctg cttttgataa ttctcgatcc ttctttgatc caaataattg ctgagagcat
     9601 ctgctaaaaa tggatatgta aaaactgcag ctccggcaag aaacatcact gccataaata
     9661 attgtaataa aagactgatt tgggtttgag gtctattacc tattttcttt ttcattttct
     9721 tcaccttctt atttaaaaaa actgcagcaa cctttataaa accgattgct gcagcttatt
     9781 tttgttgctt atacttcaga cttcatttta gatttacggt accagctgta cgctccaatc
     9841 atcaaactta ttccgattag taagaatgcc aagagcccgt tcccaccagt agcaggaagt
     9901 gacccgcgtt tcatattcgg tactctttct ggccctggat tttctactcc tacgatctga
     9961 atttcttcat tatagcttcc ataagagatg ataaattcag taaaggctgc ctcacctgtt
    10021 ggaagtacat aaccttctgg cgccatggtc tctttcattt gataggttcc ataatctaac
    10081 ccttgaacct caaagtatcc atttccatct gcgacaaatt ctgttgcttg tccgcttgtt
    10141 gcccactcaa ttctatctgc tcctgattca taaacagcta aaggcgactc ccctttataa
    10201 aatattgcgt attcagaacg gtcttcattc cacaattcga atcttgcatc tttaagcaat
    10261 tcactgcttg atgcatcata tttttcaaac tttcttccac ctgttgtgac tttctctggc
    10321 ggctctactc cttcttcata atcaaattca tcatttcgtc cgatttcaat aaccgctgtg
    10381 ttgttatgga aatcatccgc ttctagttct gtggaaacct tcaaattata cgtgatcgtt
    10441 aaatctcctc cacgtgcatc tgctaatcta cctaaagtat ctactttggc tactccattt
    10501 tcttctgtca aaatcgtcac gacaaacccg ttgcttacta cttctactat ataatcttgt
    10561 ccttttgtta aaatcgtctc gccggctcgc acttctattt cctgatcata ataagttaga
    10621 ccaactgtag gcgtatctgt gattttgtaa tttttgataa cagcgcttcc gttttcaagg
    10681 acagaatcga tgaaataagg aataggtgct gtgatcgtgt aagaagccgt ttttcctctt
    10741 tctagatcaa tataagaaat cgtttcttgt tctccagctt cattaataat cgttacttgt
    10801 ctaaggtcgc tttcctctac attcatctgt ttatctgctt ctctgatttc gtttttcgga
    10861 tacaaatgca catctgtatt gtatgtgtct ttccatgtag aaccatccca cacgccatcc
    10921 accatatcag gcatcatcac tggcatcata acaaccattg gagacgcgat tctggaaata
    10981 tgagctggcg aataagtttc taagaaaaga tagactttat ctctagaaga aggtgcttct
    11041 tccgtcactt ggacggtaga gaataccgct tctccagctt cattcgttgt ttgtttgtca
    11101 atacttgtca gtcgatattt taaaaaccaa ctttctgtgt gccgtttttg aatccattca
    11161 atcgcttcgg cagaattaag accgtcttct cgttccggtg ttaaaggatt atctcgaatc
    11221 aaatcgtaat atacttccgt tacgtcaaac aaatcaaaat cgactcctgg aatattttct
    11281 tcaccaaaat ccgtagaaac caatccgcta ttcggtcgtt cttccggaac agatgagaaa
    11341 ccttttttgt gtaatgtaat cgtcacttca cttggttttt gtgcgacttc ttcggctttg
    11401 actagttttc cgttcccgaa aatccctatt cccgcagtaa cgagtaacag tacactcatt
    11461 cccgtgacaa tcattttttt attcattttt ttctccccgt tcttttttta ttaataaaac
    11521 agcacctaac aataaaagaa ttcctagtaa agaaatcaac gttcttgctt cattcgtttg
    11581 cgggaatacg gaccattttc ctgattgacc tggattgctt ggaccactcg gctctttcgg
    11641 tttgtccgtt gtttctttta cggtctcgtt ataaacacgt ggtgttgcgg attcataggc
    11701 agagactgga actttcccgg attctaattc agccatctcc tgtccgttaa ctactacata
    11761 ttgtggttgg ccttttgcat ccacccaaaa ttcagggatg atgacctcga ttctcttact
    11821 tgcttcatcc atctcgtaac cttccacacc ttttaattct tcaaaataat aggtgccaga
    11881 aggcaagaaa cgttgtcctg tcgtaacaag gccctcttta tccgaaatga atttgcttac
    11941 atttttgtca ttcaaaggat cattgtctgc tggtttgatc cattgatttt tcaagtcatt
    12001 agcaggagcc atatctaaat aatatttccc cccttctatc atctgatata gagcaaaaac
    12061 agcaccttct aatggttttc ctttttcagt tgttcctctt tgacgtccat acttgaagaa
    12121 gtatggatct cttagataac cgacattttt aggatagata tgaatctctt gcagttcctc
    12181 ggttgattct gtcgggtgat aaattggcaa aatagcagca attgggatag ctgtctgatc
    12241 gatatcaaca tccaatccaa cttctggatc aatcgattct tcgaaaatca aataaactgc
    12301 atcccgatct tggtttttct taggtgcttt gatacgtgca atcccgtctc ctaatccgcc
    12361 aaccgtatct ttcccagttg ttaccgaagt ccctatttgg acaagccttt cttctgtgat
    12421 tagctgacgg atattgtttc tgttcgtttc agcgatttgc tggacgaatt ctttaggagt
    12481 catgttttca gcagcttttt tttcatgata ataatcggtc atgtcgtaaa tggcaaatgt
    12541 cgctccattt agtggcaccg tctgtgaaat gatatctgct gtttcccctg cttcctcaga
    12601 gatagccaag ccatcatttt catggtattc aaattgatcg ttataatcga tatctcgaat
    12661 catccgttta tgcaacacga attccacgac atcttcccct gattcttctg ccgacatcgc
    12721 atgtggaaga aggactgctg caagcggtag taaaacaagt aattgaagca tcaaacacaa
    12781 cagctttttc attaccttgc tccctccttt ttagattgtc tgacaaacaa accataggct
    12841 gctcctgcaa gcgccatgaa gaatgcagca agcaggatat agaataatcg tccggatcct
    12901 cctgtagcag gcaacggatt ttcaggatcg ttcccgacac taagctgtaa tctgattcga
    12961 tttgtctcca aaagttcata ttctaactct tgctgtagat caggcgtctc tgcttcttcg
    13021 tttggataat acgaaatctc aacttttagt gtacccgctt cttttcctgg aactacccga
    13081 tcattttcta tgtcaggttc ttctcgataa ctaatttcta aaataaagta acctggaagt
    13141 tttctatagc tgtcaggtga cttcacttcc ttgatccgat agaccccttc caacaagtct
    13201 gaagcattga atagggaaga atcgtttgga tctggtgcca agcctccctc gatgatttca
    13261 tactctcctg cactattttg tttctcaatt gaaaattctg cgccttcaag acgtcggcta
    13321 ttcatactgt caattttcaa aagttccaaa tcgattggcg ctagttcatc ttctaaggtt
    13381 acttgtagta caccatcgat gatttcatag ccttccggca agggagcagt ttcgtcttcg
    13441 atgaccgtat cttcaatgat aaacttacct tcttcattca gtgcaaactg gaacacttga
    13501 tcagatagcc gatacccatt tggtgcgaca gattccgaga cctcatattc accaatagac
    13561 agatgcagag gttggtcgta atttaaatcg acatactttt ctactcctac ggcacgagaa
    13621 tagaagtatc cgatcccagg caaacgtttc gattcttctg gttctaacgg attaccagtg
    13681 tatgctcgat acagcgggaa ggaagaatcc cccactttcc tgatatcgaa acctgcacca
    13741 tctaatgtat ggccttcatg gtctaatttt ctaactcgga tctcccgata atcaaacgta
    13801 ttgtaagcag tgaatgctac ccataaacga tcctcttcat ctgttgtata cgtgagatat
    13861 tgccaatttt cttcacctgt ttgcttgagt tggatagtcc ctatagcatt atcgtaaagt
    13921 cgcaagatcc atgtgtcatt ttcatcaggt tctttgaaac cttctgggtt ctggctctca
    13981 atgattttgt attctgcata gttggtagtt tcttcactat ccttataaac aaatgaatct
    14041 ggctctccga ttggatgaat aactttctca ccatccacga ttacatattt cccgtcttca
    14101 tctactgaat agaacgtgag tctccctttc tcttcctcta cttcgttcac accagaaagc
    14161 cctttcgcta ctggatatcc gatttccagt ccgttaccat ctgtttcata aagttcaaac
    14221 tctgcgccat tgattggcat attactgcct tcaattagtt tattgatatt catgtggatt
    14281 ggcttgaatt catttcgcat ttccagtttg acatacaact catcatactc tgtgccttct
    14341 atgttaggct cttgtacaac agaaagcttg tgatattctc cttcataata ggaattcgga
    14401 tctttacctt ccggtccgcc gactctcgaa ccagatgtat attcatctac aagctcgtag
    14461 tgacctaaca tctcatcttc gttggctgca tattttttga tttggaattg atacgtctca
    14521 tctactaact gataacgtgg tggtccagcg atctctctga tccaaaatat gtcgctgact
    14581 gctccagttt catctcctaa aatcggcatc ttcgtttcaa agatcgctat tccgtccgtg
    14641 gtagttttac ttgtttcgat tggttcggct tccccactct ctggattttg gtcatataat
    14701 gcaaattcga ctccagccaa cggctcgcca ttttgaccct tcttgctgac ttggaaatta
    14761 cggcctttat gttcgtaacg aatggaagaa gatgggaaat acatccgtcc agtagtgata
    14821 tcattctcat aatcctccag gttctgaata taggccatat tgttcactgt gcaaaaattt
    14881 ccgtcttgag ctcccgcatc aagttttact tggtacttga tcctgaccat ttccccttca
    14941 cctaaagaaa tcggagaaaa tttataagct tggttttccc gtccgacata cgttgtcgga
    15001 gtcgccacta cttctggtgg ggcttgtcca tgacgttctt catcccatat ttctggctct
    15061 tggtacttca tgccgttttc tcctggatct agatggtaaa actgaatatc tgccgatctg
    15121 ccagctccaa atggtgagac attaaaacca gtttcatcat aaagtgtggc ttgctggatc
    15181 gttctcttga aggtagaaga gatatcctcc aaggctgtaa caatgtcatt cttgttgttc
    15241 gcattgtaat atcgcggtgt tacgccatct tcttctaaat cagcaatatt tttcaataca
    15301 tttcgtccaa tagcatctag tcgttgtctc ccgctaacgt ttccatcgat tcctaaacca
    15361 atggagaaga tacttggcgg gttctcttga tacttgtttt tcagccaatg atgataagca
    15421 actgtgttga tcgcagatga cttttcttgc gaagtaggac tgccattcgt attgttatta
    15481 gaagaaccat caccaaccca gtgagtcgct ttattatctc cttcttttac ctctccataa
    15541 cgatagtgta catttacttc atcttctgga cggttaaagt cagatgcata ggtaactgga
    15601 tgagtaaacc ctgcattaga agtattccca gaaaactcct caaaatttct gaacaaaacg
    15661 tcattatctt cagcaatctt atcttccatc acagtccagt tgctccaagc tccattagtg
    15721 ctcgtacgat aacttgactg aatcggtgca taactgaagg tcggtgtccc atctcccaca
    15781 acgattagga ttttttctgg atttctattt tctccgccat tgtctttata caatgtttca
    15841 tagccatttt taagccctag tgtaagcgga gttcctccga ttggtgtacg atttaatgct
    15901 gtattctcac ttcccgtcaa acgattgata tcatttgtca atggaaagat gtccgaactg
    15961 atttgctcat ggttattgat agctgtacta ttatggtaaa aattcaccat accgattcga
    16021 atatccagac tcgggtcaga gagcagatct ttactcattt cgtttactgc ctcaatcaac
    16081 gcagcatttt tagtttgact attggtccca gcggttaatt cactcatact cgctgactta
    16141 tctagaacaa aaacgatatc gattggactg atttcctttt tctcgccccc gatgacatct
    16201 agatagacat tgtaaagggt tgttgcatct tcaggatgta gatcagatgc tgtgctgctt
    16261 ggcagaacag gttctaccca ttttttgatg tacgccccgt tataatccaa gtaactgttt
    16321 tcaaaattcc gttcatttcc ccaaagctga acggtttgag ctggaacgtt tctatcttct
    16381 tcgcctgcag ttgatccatt attagtagca tagtcgtaat ttcgccagtt cgctcccccg
    16441 tttgtataat cactatcatc gatcaagttc tctccgtcat atggcgagcc tttgtctcct
    16501 tgatagcgtt cattgctttg tgtccaattt cctaacactt ttgtatagtc attcgttgta
    16561 aacttcgggt agcgatgctg ttcgttttca acttctccgc taggatagat atattcatag
    16621 gggtcttgcg tagctgttgg cccaagacgc tccaaaatac cgttgaataa ctggcgttga
    16681 atgcgctgga gtgcttgacc gctgggtacg attggttcgt ccagcttttc catctcattt
    16741 tcttcgctac gttgaatttc agcggaatct tctgtatcag tttcattttc ttgtaattct
    16801 tggttatcta ttctttcatc aaccaccact tgaagaggta gttacccttc gttcacatcg
    16861 gggatctttt ctgtttcaaa aatcaatgtg ccggtttctg cttcttttga ataaactttt
    16921 ccgacatacc attcttgacc atcgatcgtc tcgactttta ggtcttctcc atcttcatca
    16981 taggaggata gacctgttcc acgaacgttt tttacggtac caatcccggc ggctgccgca
    17041 tcgattgcta aacgtattct accttcattg gcactttcct ttttttcaaa agccagatgc
    17101 cattcaaggg tttcttcttt ttcaatatac ttcccttcaa tttttgcata gtcctcatct
    17161 aagaatacct catcctcctt tgtttctgtt gactcagcag ctacatccag ggtcgtcata
    17221 tgatagactg actggaaata tggtccaaat agcaaactga cagttactaa ctgcaaaatc
    17281 ttcaatttta accctttcac atccttatac tcctttcaaa aatatttgtc ttctttcaca
    17341 acaatcaaca aaacaatgcc catctaatta taatttaatt taattttaat tttaaatcaa
    17401 atgatatcct ttttagttaa aaaacaccaa ttatacaaca tttattatta aaattaaatt
    17461 ataaaatttt ataacgttct catttaacaa aacttaagtt attaagacaa atgaataaac
    17521 aactacgctt tcctcgaaac aaaaaaataa agcacaaatg cgcatttacg cactcatgct
    17581 ttattcgtac aattaattca gataacggca gcgcatagga tgccaataac acttcctaaa
    17641 atagctcctc ctaaaatgtc agtaggataa tgtaaaagta aaaaaatcct cgaataagcg
    17701 atcaaacaag caaataaaaa ggctaatatt cctgcaactg gacttaattc gaacaacgca
    17761 gctactgata aaaaggctag cgctgtatgt cctgaaggaa aagaagaagt cttcggttta
    17821 cttgtgtaaa ggacaagccg acgatttttt tcataaggtc ttttccgtct tgtcgttttt
    17881 ttgataaaaa gcaaaccaac aaaaaaatag atcaaactgc cgataagaat ggctagacca
    17941 tattctctag tatcaggtat caagactaaa acagcagcaa ggagcaacca aataaaacca
    18001 ccattagaga tattactgat aaatttcaaa aaattgattt ttcgactatc cgttttccgt
    18061 tgcttggcga acttgttgat aatactatca tcgattttag caatcaaacg caacatgtta
    18121 ttcctccttt ttaagaacct tttcttgcgt acgatggata aaaagcagga cttgaaaata
    18181 aaacaagaaa ctgaaaccta ataaagcaaa atagattggt cctgcaaacc agaatgcgac
    18241 aagaaggatc aacgtgcctg ccaaatagaa aagcgcgctt ttgaaatcat taaaaaacaa
    18301 gaaaaatgca gtaatccaag aagcttcttt ttgttccagt tgaagcaaga ttttgtaact
    18361 aaagagaagc gcgcttaata gaagcaaaaa caacgtagta tacatcaatg tatagccaat
    18421 tcccccaccc caatagcgga aaatctgata atcgatcaat agaagaagaa aataaacact
    18481 tgctaaacta tcttgctttc cataaagaga gaagttctca cgaaactttt tccagaatag
    18541 tgaaccgagc tttttctctt catttttttt gtaatgataa atcatataca gaactgttcg
    18601 acttgcagtt cctaatgtga aaacaggcaa gacgcacagg aaccatagta gctgtaaatg
    18661 gataagacgt ggaatccatt caatgatttc taagaaataa tcattggctt ttttaccaat
    18721 cgatcgattc atcatccttt tgaacctcct gtcaaatcca tcccttcaat gaaataacgt
    18781 tgtgcaaaaa agaacagcaa aatcgtcggg atcaagacaa gtgttgctcc tgccatcaga
    18841 taattccatt gtgtcgttgc ttggttctga aaaacttgca agccaatctg taacgtgtat
    18901 ttttcttgat cttggatata taacagagga cctaagaaat cattccaagc tgcgttgaag
    18961 gaattgatcg caatggtaat caaggcaggt ttcgtcaatg gaagcatcaa atgactccaa
    19021 atatacaaat gattcgctcc gtcgatttca gcagcttcga tcaattcatt attgatcgat
    19081 aagtaaaatt gacgcatcag aaatatattg aacgcattgc cgaagaacga tggaacgatc
    19141 aggggcaaat aagtacctac ccagccgatc ttggagaata atacatattg agggatcatc
    19201 gttacaaacc ccgggatcat catcgtagaa agaaccaaag caaacatcag ctttttccca
    19261 ggaaaatcaa gcttcgcaaa tccataagca ataaaagaat ttgaaaggac attaccgatc
    19321 actactagca cagtgatgaa taatgtattt cttgcatagc gccaaaaagg aaaggcggca
    19381 atcgtatcca gatagttttc ccatacgatt ttttctggga aaaaggtcgg aggataacga
    19441 acgatttctt ccattggttt caatgaagta aacaccatcc aaagcaatgg aatgatcaaa
    19501 atgattccta ttactgtcat gaggacataa cttagtattt ttttgtttgc cgattcacac
    19561 tggtcttttt gaaataatcc atcatttgcc gtcacctcca gaataataga cccacttagg
    19621 tgcaagcttc aaattgacaa acgtcagaac caacacgatc agaaacagga tcattgacat
    19681 agccatcgca taacccatat caaaagctac gaacgccttg ttccacatat gcagattata
    19741 aaaaagcaaa gaatttgcag gtccgcctgt tccatttttc gtcatgacat aagcttcttg
    19801 aaaaatttgg aaagaaccga tcgtagaggt gatcacatcg taaaaaataa taggagtgat
    19861 taatggcaaa gtaatacttt tgaactttcc ccaaacgcct gctccatcga tttctgctga
    19921 ttcatataaa gatctaggaa cattttgtaa tgtagctaag taaagtagca ttgctcctcc
    19981 agaactccat attttcatca aaatcaacgc aggtttcgtc cattgtggat caaacagcca
    20041 agctggtcca gggatatgga accagcccag aaatgtgttg atcaatcctg cagatggaga
    20101 aagcagctgc atccataaga tgtagactgc tactcctgat aagactgccg gtaaatagaa
    20161 agctgtacgg aatacactga ttcctttgat tttttgattg agtactgtgg ctaaaaacac
    20221 actgaaaatc gtcgtcagcg gtacattgaa gatgacgaaa taaacggtgt tgtataacga
    20281 tttccaaaat aaatcatcgt gaacgaacat tcttttgaaa tttgctagac caatgaaatt
    20341 catcttggat gtcaaattat aatcggtgaa actaccaata actgaaaaaa gcataggccc
    20401 tagcataaat accaagaacc cgataataaa aggcgagata aataaatagg cccatcttgc
    20461 ttcttttttc tttcggatag ataaacgctt caaattttct tgcctcctct gtacctagac
    20521 agtcaaaaat ggattattga ttttgcttga ctaagttttc tactgctttt tgtgcatctg
    20581 ccaatccttc ttttggtgat tttgttccta aaagaatctg gtcaatctgt tcattcacta
    20641 atgtcgtgta atccggagca tctaaaggaa ctggtgtgat caccgtattt ttaaagtttt
    20701 cgtccgccat ttgatagatc atttttcctt tatccgttag gttgtcatta ttcactaaat
    20761 tctcattggc tgtcttgctc gccatgatat caaaactttt ttcgccgaat ttttcttgta
    20821 cttctggaga agaaagatat ttgatgaatt cataagaggc ctcaggatct tttgctccgt
    20881 atggtacttc caagacgaat ccgccacccc acgaccaatg gcctgaacct tcttcttttt
    20941 ctgggagctg catcacgcca aaatcaaaat catccggtgc attttccatc aaactagagt
    21001 aataattgat attttgggca cgcatggcta ctaatccgga aataaatgga tcagatacac
    21061 cagacccaaa ttcggcttct aatttattga tcgtattttt cccataataa tcttgccagt
    21121 cttggatcca ctccaaggct tccactttat ttttagtatc aatcttgact ttttcatctt
    21181 tgtcaaacca actagtcccg ttatctgcgt ttagcgccca tacatcagcc cctaaattcc
    21241 ataatggata aaaaccgatg cgtgtaaatt cttttccttc ttttttatct agtttacgtg
    21301 ctgtttcttc taattcatcc caagttgtcg gtagatcttg ttcactgatt ccagcttctt
    21361 taaatatctt tttattataa aaaatgactt gtgtatctgt attgaatggg atcgcataag
    21421 gatcaccttc atattctact gtatcccaaa gctgcggata aaaatcctta gaagtgtctt
    21481 tttctacata tttggagaga ttagttgctt gctgtgcttc tgctctttgg gcaacggaat
    21541 ttatgtcctg tacaataaca tcgggtgcat ttccagctgt tattgcagat aaagatttag
    21601 tccagatgtc accccatggc tgatacttat aatttacatg gatctcgttt tgtgattgat
    21661 tgaaatcctc aatgatttct tcgatagctt cttttcgtgc accggatccc caaaaggacc
    21721 agaaatcaat attttttctt ccatcacttg ttttttcaga agaatttgct gcacttgaac
    21781 tggcatcgct tgcattactt gatccgcatc ctcctaataa aaacaatgct gaacttgcca
    21841 gcaaccctgt aaacaataat tttttcatat tttacctcca aattttaatg taaccgatgc
    21901 cggttttaat ataacgatat cattttgttc tgaaaataac aatttataag gtatgattct
    21961 aaaaaaatta ttaatgatac caatacttta tataattcgc gagcgctttc tttgaatttt
    22021 ttaatctttc gtagcagaat gagaatgtat taaaaataga ttaggaggaa ttttgatgtt
    22081 tagacaccag aaagaattgc agtttgaagc aaaaccagat cgtccgaatc cattaatcgc
    22141 gaaatatctg caggagctga tcggcggcca atatggcgag atgagtgtag ctatgcagta
    22201 cctgttccaa ggctggagct gccgaggaga agaaaaatat aaagatatgc tgatggacat
    22261 tgcaacagaa gaaatcggcc acgtggaaat gttggcgaca atggttgctc gtttattaga
    22321 gggtgcgcct gttgaagatc aagaagcagc gatgcaaaaa gatccaacaa tcggtgccat
    22381 tatctctgga atgaatccac agcacgcgat cgtagctggc ttaggacctc gtcctgctga
    22441 cagcgtgggc aatccatgga gcggtgccta tatcattgcg agtggcaact tgttagcaga
    22501 ctttagagct aatttaaatg ccgaatcaca aggaagactt caagtagcac gtatttacga
    22561 aatgatcgat gatcgtggcg taaaagatat gctgtctgtt ctccttgcaa gagatagcta
    22621 tcatcaaaat ctatgggaat gtgcagtgaa agaattagaa gaaaaagaag gttcaatctt
    22681 agtcccaagt actttcccgc gtgacaaaga acgaaaagac attgcttatg acttctataa
    22741 cttctcagag ggagaccaaa gtagtgaagg ttcttgggct agtggcaaag cactggatgg
    22801 cgaaggcgaa tatcaatggt tgaaagaacc taagatcgaa ggcgctgcac caaaattaga
    22861 accagtaaca ccaaaaatgt atgggacacc tccattcaag aaataaatat ctacccgtag
    22921 aaacacccgt tttttgttcc acacgctttg tgagcaaaac tgactaaagt cattaatcat
    22981 aaccaccctt caaaagggtg gttttctcta gagctataag ctcaaatcac cggccagcgc
    23041 ctaaagacgc tggctttcat attttatgtt caagccatat tgcctttgcc agttttgccc
    23101 acctcttaaa aggtttatgt actactcctt agcccttaaa aggatcgtct tactctcgta
    23161 cactcagctt atctaacgca ctatcatgtt tttcttgttc ttgaatgtac tttttgatgg
    23221 tcgcttcatt ttgtcctact tttgtcacat agtatccttc cacccaaaag tgtcgatacc
    23281 caaatttata ttttagattt gcacaatctc ttgatgatct cctgaatatt ggctcgatat
    23341 tgattataaa ttatttttct tctatacttt ggtgtgaata caatgtggta tttacacatc
    23401 tactttgtac gggctaaact atttcccttt attgctccac ccgcatagca agtggttttg
    23461 tatttcaatc gctcggcgcg ctcaattagg tctaaagaca ataaatctaa aaacccgctg
    23521 cttcactgac agaaacaacg ggttttcaga aaaaaatgaa atgaaaaaga tctcttacgg
    23581 caatctattt tatttttttg attttttata aatggaaaat gcttcaagaa gtccaagaaa
    23641 taaagccgta taaaaacaag aacctatgaa atctttattt attagatatt caacagaaat
    23701 cccgataaca ctagccaaca atatatttat cagaagtgta aaataaggat gctttttata
    23761 gaatagaact agtgttgttt tcatagactc tcctttcttc atatttccaa ttaatcacaa
    23821 attcacggca ttactagaaa aattaaaggg gcgcagaagt ggaaaaatac tcttcgactt
    23881 tccctacaaa ccaggccatc ttgtgtttaa taactatacc aaatctaagg tacctctaaa
    23941 tctaaattcc atttgtggcg gtgacctcca atttttaact cttctatctc ccatccagta
    24001 tacataacct tgatacttcg accacttata tatcgaacac acaaatacct atccattgca
    24061 ggagtactac ctaacttagt tgctacttgc atctaaataa cagctgaaaa gataggactt
    24121 actcttagta aagtatctga actattaatt tttaaactat catttttatc ctcaactaca
    24181 tgcacatctg ttgcaacttc actttctgtc tcatccagat aaatgattaa ggaatcggga
    24241 attgcaatat cttcagctga cgctggaata gttgagctaa attagtcatc atatctttat
    24301 tataaaataa ccaacagcaa aaaatacaat gaaaaacaaa cttggaacta atgtatcatt
    24361 aataaatgtt gaaaaattca gcaactcatt actgtatgat tttagcagcc caaccaacat
    24421 ataccctata aaagctaata agatggttag gaatccttta gaatttttac tcattcatag
    24481 acacttcctt aaataacttt tattatagaa ggtattgtaa ataataatat tgacaaaaag
    24541 tgactcaaaa taaaaaaaac cttacattat actggaatga actgtattga tagtgtacct
    24601 aaaagctcta ctgacataag atcgtgtaat cggtaaagta attttattaa ttatacggga
    24661 tgtaatcaat tagagaataa actaatcata aaaggtactt ttacattcat aattgtcgct
    24721 ttgagattct actttggttc actatctgac ccaattgcac attttcgatc attacaagta
    24781 ttggtgtcgt tagaacaact aaataaaaac tagcggtaga tttttcagaa tctatgctaa
    24841 tttctgtatg gatgttccag tgatggcaaa tttctctttt cattgttttt cttgtcgcat
    24901 gatatgcctt tttgtgttat tcagttaaac tatagaaatt ctttcctaga cagatcttga
    24961 tcccaaattt tacgtttttg agcatcgata tagtttaaaa tgacattact catatctaaa
    25021 gagtttagat tttttaggac taaaactgtc agttgttctt tttcttcttt ctgttaaagt
    25081 attgtcgcga cttttcgtat acgttaagat atgtcgtgaa aaaacaagtt ttgtgacaca
    25141 aaaaaacgaa tgacttgagg aaatcacctc aatcattcgt ttaaaatgct atatattctt
    25201 tagtttaaga tacggaaatt aatgccatcg accacactag tagaatgaac gacatttact
    25261 tggccttttt ttaatttcgt tatgtttagc atataaaaat attatagagt ttacttacaa
    25321 tgcttaaaac atatactgta taatctgatc aattttagcc atgtcttgca atggtaagtt
    25381 ttctattttt ttgagttttc gttccttaaa atcaagagat tttaattgtg taataattac
    25441 ttgtcctttt atatctagct cttcaggtaa tgagtaacgt gtcggtaaat tctttatagt
    25501 ggaagtaatt ggacatatga ccgaaaacat tgttttacgg ttaaattcat aacgagagac
    25561 gactagtcct ggtcgtcttt tttgaatttc ttttcctacg gagggatcaa aatcaatcca
    25621 tacaatatca ccttttttag gaatataaat tctttcttct gacactataa aatttctctc
    25681 ccttcaggag ttaaatcttc ccattcgtct ttctcataat actcggcctc ttccccacca
    25741 ctaaatggat cttcaatttt tggaactaac gtaattgttc catcatcaga atacacaacg
    25801 atatattctt ggttttctga aggtttcttt ccgttatcag aaggtaaagt taccactaca
    25861 gaacttcctt gtaatctaga ttttgtaaca agcattatca tcactccctt aataaaagta
    25921 tactatataa cactaagtaa cgcaaaattc ccctttgtaa actatctaga aaattgtttt
    25981 gtttaaagta tatcttattg gatataaata gaaataaatt gtagccagtt cattttttct
    26041 ttaactaaaa aaataatcca agaaacattg aacctatgga tccaaaagct acccaaatac
    26101 tatagctaac cccccgctac cttcaatttt gcagataaaa cgctttggga gaaaatttca
    26161 aagacaacag gccatcctat catgcccgat tataaacaaa aagctggcta ttccttttgc
    26221 tctgacaaat ttcaattggg aaagttcacg aaactagcag gtgaagaagt ttcaactgtt
    26281 cggatcaaag aatgcccgct tcaaatagaa acattggttc aacgaatttc aactagacaa
    26341 gactttgcta ttgtagaacg tgagatcgta gctatttttg tagaagaagg gattttacat
    26401 gatccaactc atatcaatgt ggataaatgg caacctctta tctataaatt cagagaatat
    26461 acaactgcca accagtcgtt aactttgaat tttagattcc aagaattcaa agagtcataa
    26521 tgataaacat cgttaggtat aaataaaaaa gactcgcagc acgagtaaaa aacaaataga
    26581 agctatacat tagaaaggtc gactgtgacc ctatagatgc agtatatgca gcttatgagc
    26641 atttcttctg ttctctttgt ttttgggatc tgtgctgaag tctttttcgt tttttgccgc
    26701 tctttctttg aaaaatcgat tatgttatac cttctccatt actaattcag gcatctgctg
    26761 agtaatgatt tttcgcgcaa aagaaatatc tgttacccaa ggttcgattt gttcttcagt
    26821 caagacaagc ggcattcggt catggattgg tgcgactgtg cggttaggtt cagtagtcat
    26881 tatgattgat tctgccattt tttcatcctg atggctacga taaaaaccgc caatatacac
    26941 tattttttcc ttatttgaaa acataaattt gtctttttct tcattccact cattgggaaa
    27001 acacaacgat tttgcaaaaa tggttgatga aaggtctttt tttcttctac tgtctctgca
    27061 cgggcattaa tcatcaattg tcctttttta aatccggtaa atccccactt catgatttcc
    27121 ggagtgagga tgttttcttc ctcttttctt aacgtcacaa caagatttga cggaaaaact
    27181 tctccagctg ctaattctgc tgcctgcttc ggttgtttcg tctgggcttc tcgataataa
    27241 ttctgaagga gctctgactc tagatcaaaa aaataacgac cacacatcct aatccctccc
    27301 aatctttttt tctatcatac actgcaacaa gaagttcgca ccaacaaaac gctttcaatt
    27361 tttgtagaac taaaaaagtt gtgacaagtg acaaactctc cagtgaatgg tattctcctg
    27421 ccaactcctc ggtcacaagt cacaatattc aacaaacatg agaagctgct ttttgaaatt
    27481 gttccttgtg actcggagtg aaacggcagg cttacgacct ctgggtaaac ggtgttcaaa
    27541 agccagtttc tcggtattaa gccaaattta tgcaaaaatg tagaaagcta ttttcacaaa
    27601 atttttctta atactcgaaa ctaagcgact ttttcacaac ctcttcctta aacggtgttc
    27661 aaaagcttgc atctgcggta ataagcccaa ccaaacgaaa aatatgagca gctattttta
    27721 tttggctgtt cttattactt gatgcagggc agctttttca caacctctcc actaaacggt
    27781 gttcaatcag ctaaccttcg gtattagctc aaaaaacggc aaaatatgag gaactatttt
    27841 gccgtttgtt tctctaatac tcaggtcaaa gcgctgattt cacaacctct aatacacggt
    27901 gttccagaag tagcttcttc gaaaaataag ccgaaatttc acaaaaattt gagaagcaat
    27961 tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctaattatt
    28021 aaagaacctt ttgcgaagtt aacaatcttt ctttgatcaa ttgaaaattc tgcctaagta
    28081 gtgatagatc ctgtgtgact ttcaacaata agatacttcc ctggatttca gcaatcaacg
    28141 ctttggcttg acggtctgct tcttcatcgg acagtttttc ttcagaaagt gccaggatat
    28201 tttgtttcgt atacttgacc cattgattga ctaattctag tagcaacaga cggtattctt
    28261 catccactgt actcaactca ataatcaaat tacctacagg acagccatga taagtgatct
    28321 gtgtctcatg atcagcgaaa atccagtcca acatttcttc taatgcttct tctggctgtt
    28381 ttccagcatt taagatgtct tcgaacaatt ctgtctgcca tacgtccata tgcgcatgga
    28441 tcaccgctag acaaacttct ttttttgaag aaaagtaata ataaaattga ccttttcctg
    28501 tatcagaagc tgctagaata tctcggattg acgtttcatg atagcctttt ttataaataa
    28561 gatctttggt cgcttccaag atcttttcct ttgttttcaa tgatattctc ctttttcatt
    28621 tctcatagtc ctatattata cagtaaattc atcatttttt cttcttaatc gtttaaaaaa
    28681 gactgtgcca aattatctga cacagccctc actataaaac tgttctcata tagctagatg
    28741 ttcattgatt caagaactgc gaggacaaaa gcaattccta tcttatgata gttgctctaa
    28801 tacttcctct gttgtcatca cttgatctgc aataaagcca aagttcgtca acgctgcatc
    28861 cattgcttct tggccaggag caccaattgc atctgtcgct accacaacat tgaatccact
    28921 ctctaccaat tcacgcatat gggaatcgct acacaagttt ccgttcattc caccaagaat
    28981 tactgtgtcg attccatttt ttctcaattg gagcgccaaa tcattgcttt ctggtccaaa
    29041 gattttatga ggagagctga tgatcgtatt ttcatccaaa taaggtttca attcttcgat
    29101 aaaatcggct cctgaacctt cttccactga ttcatattga ctttttctag caaacatctg
    29161 ctgctcaagc atcatatgtt ctcctgcacc gccaaattgc catttatggt catgtgggta
    29221 aaaataatga ggagaaataa agagtttgta tcctttttct tttgcttgtt ttaccatttc
    29281 aatcatattt tcgatcgtat tgtatttttc taagatatct tttgtcaaac caaagccacc
    29341 gcctgctggt ttcaagaact cgacttgcgg gtcagtgaga actactgctg tatttttatt
    29401 attgaacatg gtggattctc cattcgttat ttattttaat acatcattta gagcttcact
    29461 cattgtcgga tgagaataga tttgatctct caataacgta taaggaagtt ttccattcat
    29521 agctagcgaa atcaagttga tgacttcatg agaatcttcc gcatagatac ttgcccctag
    29581 aatcaagtca gtttcagggt cgactaaaac tttgaataca cctttaggat cttctaatac
    29641 ttgtgcttta gggacaccgc ttgtcatata cttgaataat ttgtaattga cgccttgtgc
    29701 tttggcttgt ttttctgtta aacctacatt ggataaagtc ggagtgataa atacactgta
    29761 aggcacagct ttccggttat tcgttgttcg tttattctcg cccttcaact gatccataat
    29821 gattcgataa tcatctagag agatataagt gaactgcaat ccgcctttga cgtctccaat
    29881 cgcccaaatg ttgtctgcat ctgtacgaag gtattcatcc acagcgattg ctccgcgatc
    29941 tgttagttta acatctgtat tttctaatcc aagtgatgct gtacttggtt ttcttccagt
    30001 tgcagccaaa acttttgacg cttggattgt tacttcttgg ccatcttctg taaaggtgac
    30061 ggcagctgtt gattcttggt ctgctacttg atctacagat acacctagat ggaattcgat
    30121 tcccgcattt gtcatgtctt ctaaaatcat ttgcgcgata tcttcatctt cacgtggaag
    30181 aaattcagaa tgggcatcaa gaacgacaac tttagatccg tattcattga acattgatgc
    30241 aaattccaag ccaatatatc cagccccgat gatcactaat ttttccggta attgttcctg
    30301 atccatcgct tgcgtagaat caatcaagta gcgacttgta ttcaatcctt tgattggtaa
    30361 aatgattggt tcagaaccag tattgatgaa aatccgttcg ccttcaacaa tcactttttc
    30421 accattattc gtcacttcga tttgatggtt agaaagaaaa cgtgctgtac cgtccatcac
    30481 tgtcccagtt gcctcatcgc tgatcatatg ataatttttg gcgcgaagca tgcccgtcaa
    30541 tttttctttc cgagcaacag cctctgtaaa gtcgattcct ctttctccat tgaaaatcaa
    30601 tgatttagaa ggaatacagc cgatgttgat acatgttccg ccatacatac gtgttgactt
    30661 ttcaacgact aaaaccgatt caccttttga agctaacgcc ttcgctaaag tcttaccgcc
    30721 ctttccaaaa ccgatcacaa tattttgata tttttccatc atttttccct cgcttctttt
    30781 ttacctaccg attggtacaa aaatatgata accgataatt gtctattctc caaatcatct
    30841 gctttatttg tcaaaaaaaa ccagacaaaa agcggtcctt tcacgttttt agtctggttc
    30901 gatttccttt attcttctaa acaatcgtta cttctacatc gatatttcct ctagttgctt
    30961 tggagtaagg gcagaattca tgcgcatctt ctgcaatttt ttgggcttct tcttcgctga
    31021 tgccatcgat atgcacttct aatactacac cgatctgata gccgccatca tctaaattat
    31081 aaagagagac acgtgctttt actgtggact ctgctgtcat tcctgcttct ttgatcatat
    31141 gttgtaccgc cccattgaaa caagaagcat aacctgctgc aaataattgt tctggatttg
    31201 ttccttctgc atggattcct ggaggagtga ttttcatatg catcgagcca tttggtgcct
    31261 cgacttctcc attgcgcccg ccatggttga tcattgctgt ttcgtatgct tttttcattg
    31321 tactgctcct ttcgattgac catttgctac ttggctataa ttatagtgta tgacaagtaa
    31381 ggcgctttct acaaaaattc tgcttattcg aataccagaa tgccgtcttc tactattttt
    31441 ccaaaaaaca aaaaaatact actcgtgaac aacagcgtca tatttgttcc aaaataaata
    31501 gcaatctttt ctacataatc ttttatatga ttgattttaa gatacatata taccagaaag
    31561 ttgaccccat aaaccaatac tgttaaaaaa ataaccatat tcgttaccat tttttcctcc
    31621 ttttgctggt ctccctacca gcactcgatt taaccatacc actttttttg ccgtccaagc
    31681 aactagcctt tcaaaaagac tggtttattc tgctgttaat gattcaagat cagaaaaatg
    31741 tccgaataat tttgctaatt ttactaacgc caacttgttc tttccgaatt catcattttc
    31801 tatctgtaat actagtaacg gctcatgtaa gcttaaacgg atcaaaaacc agccgtttcc
    31861 gtatggctct tctagatcat atcgaatacc ttcttcattt tccgggtcga agttcatccc
    31921 tttttcttct tccaacagtc gcttcatttc ttctaatatc ttgtttcctt gttcgcgtgg
    31981 ttcatcgctg aacaatttta atcggatttc ttgtacttct acgggctgtt tcaactcttt
    32041 gatttgttca tctaatgtga taccttttct ttttaattct ggcaaaagca tcaggatctt
    32101 tgcgatgaca tatgcaccat catccagaaa atagttttcc ttgaatgcag cgtgtccgct
    32161 tgtttcgatg gctagctgtg tatctttccc aagacggtta agttctaatg ctttattgat
    32221 tacatttcga tagccggaaa tataacgaac ttggatgcct cctttttctt caatgaatct
    32281 ttgtagatga gaagaagtag gggaattcgt cacgattctt gttcctggat gctcttttaa
    32341 tacgattgta cttaatactg cgatcaaatt atttcgattg atcactgttc cagaagcact
    32401 gacaactgca gaacgatcca catctgtatc gaaaatgatc ccaagatctg cttcatttgc
    32461 taaaacagcc tgcttgatac tttccatcgc ttctttatta tcaggatttg ggatatgatt
    32521 aggaaatcgg ccatctggtt ccaaaaattg ggaacctgtt gaatccgcac ctaagctatt
    32581 caatactttt tcagcaaaga atccaccagc accatttccg gcatcaacaa tgattttcca
    32641 accatttagt ggtttgcttt ctagtgttcc aatccccttt ttaatttttg tgactaaatc
    32701 ttgcgcataa ggtgtcaaaa ggtctgcttt ttctacgctt ccagtttgtt cgctttttat
    32761 tttttgctgc tgtgatagga taaaagcaat atcttctttt tctgctcctc cttctgaggt
    32821 aaagaatttt attccattat aataataggg aagatggcta gcagtcagca taaccgcagc
    32881 atcgcacgag aactgttcaa attgagtgga cataaacata gcaggcgtag tagctaattc
    32941 gaaatcgatg acatgtatcc cttgttcttt cagactttgg atcaacgcct ctttcagtgc
    33001 tggtccgctt atcctactgt catgaccaat cccaatcgtc cattttttat ttggatcggt
    33061 tgatttcttc tttttcttta tccagtttgc tagtccccag ccgatctttt ttaccatgtc
    33121 tgtcgtcaag tttacttcat atccttcaac tggtaatgcg attcctcgaa tatccgatcc
    33181 attttgcagc gctttcatat ctttcatata aaagtcctcc tcatttattc cctcattttt
    33241 tccagctttt ctgcaaatcg ctgtgcttct tcttctgagc ggcaaataat aatgaatgta
    33301 tctacaccgg ccatcgttcc gacaacttca gggtaagcca cttcatctag ccaattcgtt
    33361 accacatcgg caccatttcg ttcagtcaat acgataacca tgaactgaac agactggata
    33421 cgcaaaacct cgcgtctaat tgctgtacgc aaacgttctt catttaaaga aacagatggc
    33481 tggttaaata atgtatagcg tactattttg ttttcatttt gactttttac taacttcatt
    33541 tctcgaatgt ctcgagaaat cgttgcttga gtcacatcgg cgcctgcttc atgcagccgc
    33601 gcaagcagct cttcctgtgt cccaataggt tgttctgtaa tgatctggcg gatcagtgct
    33661 tgtcgctgtt tctttttcat attagacacc tctcaatgtt gattatagca aaagataagt
    33721 aatatttctt catattttgg tattttttac ttttattttt tgttttcatt caggttgcta
    33781 acctttttct attttaacac gcaaaatcgt cttcattttt tcaggtgctg attttcttgg
    33841 atcgctgatg taaatctctt tgtgttcttt agaagctctt tcatagcctt cttttgcgat
    33901 gaatgcttct aatttctcaa acgttgctgg ttcttcggca tagggcccga cgtgtaagat
    33961 ttgggcacaa agaccttctt ccatcttttt gaatactact tgttctttca agtcttccgg
    34021 aagtttgcta gaacgctgaa tggcttcttg tgctatcgct tctgtaacaa agtcaggctg
    34081 tcggatcatc aattgataag aaaaatgttc ttttttcatc actggttcat gcaaatactt
    34141 ttcttgcagt ccccattgtc cttccagtgg atagacagta tacatctgat aatcaggaat
    34201 cagccaattt tttttaggcg acatgcgtat tgcatagctg actgcatata gacaggctac
    34261 tcttcgttta aagtcttcct gattcgggtc gccgatccct ctgatgctaa agaatgattt
    34321 tttaggaacc tctagtattt gcgggctttt tttcatacta tagctcttgt ctttacgcca
    34381 ttcaattttt tccatttttc ttcctccgcg aaattccatt tagttattta ttatcatacc
    34441 tctttttgag tgacttggct aatcgtgttg acactatttt tcagtttgtg ctagaataag
    34501 tgaagtaaat aaatcgtaca gataacacgt ttcggcgtgt cgagagagag gcggtttcta
    34561 tttttataat agaaatcact ctcttttttt acgaaatttt ttagaggtga tgtaaatgac
    34621 aaaacaaaaa cagctgcttt tagtacctgc agtaattgca acagggatga tgtcttttgc
    34681 gggcgtattg atcgagacgg ccatgaatgt aactttccca actcttatca gacagtttga
    34741 tttaacgact gcacaagtcc aatgggtaac aacgatttat cttttgatga tttcgatcat
    34801 tgttccgctg tctacttatt tgaatcgcaa ttttagtctc aaaaaactct ttttagcttc
    34861 aaatctgctt ttcttggcag gtataatgat cgatttcttc tctcctacct tcatggtcct
    34921 attgtttggt cgattgctcc aaggtgcagc gacaggtatc gctcttccgt tgatgttcca
    34981 tattatcttg acatttgccc ccctcaatcg acgaggcgcg atgatgggtg tcggtacttt
    35041 gacaacggcc attgctccag caattggccc cacttatgga ggcattatga cttcacattt
    35101 tacatggaat catatcttcc tgtttcttgt gcccgttttg tttctttctt tgattatcgg
    35161 ctggtttgct attcccgaga tggcagtaca aaaaagtggt tatttggatt ggataagcgt
    35221 tttaggaatt tgtcttttgt ttagtggaag tctaacattt ttgagtacgt tgggaacagt
    35281 ttccagctgg attgctttaa tcatcggcgg tattggctgg ttcctttttt actatcgaag
    35341 taaaaaagtg gagcatccac tgatccgact gtctattctt tcaaataaaa cattccgctt
    35401 gtttttgatt ggcttcttag tttatcagtt tttattactt ggtgtatctt ttgtcttgcc
    35461 gaatttcctt cagatcgttc aaggaagtag tccttttgtc gctggattag cgatgcttcc
    35521 cggcgcagcg gttggtgctt tgctttctcc tttttccggg aaaatgctgg atcaatatgg
    35581 tccgaagaag ccaatttttg ctgggctgat tctttctttg attggttggc tagcattatt
    35641 cctactcata ggacacgctt cagtgggtgt attgattgct tgtcatgtgt tttatatgat
    35701 cggtatcgga ttatcttaca gcaatatgat gaccaccgga atgaatgcac tgaatgaaga
    35761 actacaagga gacgggaacg caatgttcaa taccttgcag cagttttctg gcgctgtggc
    35821 tacttcatta gtagcggtca ttatcaatta cgtccagcat catacttccc ataactatga
    35881 agtgtctact acattaggat caaaagcagc attaggcgtc ttgttgctgt tgcttctcgt
    35941 aagctttgct cgattcgcct attatctgtt ctttgctaaa aaagcgtaga ttccatatac
    36001 ggcaggtgtt gcatctgccg tttttttgtg tgaaaatggt tgtttgtaaa aggaggcttt
    36061 tttatggaaa aaattgccat tatcggtggc gggatcattg gtatgaccct agccagttac
    36121 ttagatacat caaaattcaa tgttgcttta tttgatgaag ggacaggaca ggcaactaaa
    36181 gctagcgctg ggattatctc cccttggttg tcgaaacgca gaaacaaaca atggtatcgt
    36241 ctggctaaag acggcgctgc ttttttccct aaacttataa aagatttcca acttgatcaa
    36301 acgatttacg cacaatcagg gacacttttg cttcgacctg aaaaagattt agctgaattg
    36361 gctgttcttg ccgagaaacg aaaagaagaa gcgccagaaa ttggaaacat cgaatggctt
    36421 tcacctgaac agacatctca agcacttccg ttattgaaac cagcagtttc actgcgtatc
    36481 agtggtggtg gtcgtctgga tggaaaagca tatttagaac atcttggtca gcgtttagca
    36541 caaaaacaaa tggagcagat ccaggcaaaa gtcactttgc ataagaagag cgattcttgg
    36601 ctcatcaagg gaccgtttgg agaatacaca gctgatcgtg taattttgac acctggcccg
    36661 gcacttaagc ctttattaca agaattaggc tatgctgcag atatacgtcc gcaaaaaggg
    36721 cagctcttag catttcagac atcttataag atgagtcaag actggcctgt tgctatgctt
    36781 gacggagaag ctgatttcat tcctttcatg gatggaaaga tccttttagg tgctacccat
    36841 gaaaacgatc aaggctggga tttggctcct actagcgaag cttataaggg attgactaag
    36901 agtacagaac agttcttgac tgatccagat cagataaaaa actggccata cgagttccgt
    36961 gtaggtaccc gtgcttatac gtcagatttt tccccatttt tcggcgtact gccagatgat
    37021 ccaagcttac tggctgctag cggtctaggc tcttctggct tgaccacagg tccttatatc
    37081 ggctatctat tagccaactt cttaaatact ggtcattggc ctacggaaga ttatcaaaag
    37141 gacatctcca cctatattac gaaaaatcca tcatagaaaa acagcttttt caagtaagga
    37201 tcccgagcga tattgcgcat ggattacttc ttgaaaaagc tgttatttta gttcaatttc
    37261 tgaatcaaat tctccaaact ttcttttgct tcatctggca agagatcttt tcctatctga
    37321 gcttcaatga atcgtaaacg aatatcaagt cgttgtttca ccagattttt ataggacgta
    37381 tcctcaaaag aaacaggaaa atctggtata ggtaaatagt ggatgtcttc aaatggacca
    37441 aacgacttga attctgccgt ttgttgcacg attctttcaa cgattgacaa tgtcgtttca
    37501 ggtttgattt ttttatcatc gaaatatcca gtattcagga catagcaggc tgtttgctgt
    37561 ttcaaaaaca actctcgaaa agcttgatag tcttccctaa gaggatagac acggaaagga
    37621 ttagcaaatg gttcaatgac tagctcatct agctgtcttt ttgtagtgat attttccgcg
    37681 tctgatcgtt ttgttgctaa tgttgcacca aaagacgctg ctaaaactgg gtcattgatc
    37741 ttgataattg gcggaagcga atcatctttc atgatccaaa aaacagcatc gatcttttcg
    37801 ctaagatgat cgactcggtc gggtgtcgca taacgtgatt tgactgtccg cccatttccg
    37861 tttcgtatat ctcctgttac taggactttt tctcctttac ttgtacatgt cacgcccaca
    37921 ttctgacaag taaggaaaga agaaatggcc ggatcatcag acggatagtc ttgtgtttta
    37981 tcaaagtaag aaggttccaa ggcagtagca aaaccatttt ttcgagaaat aacgaaagca
    38041 tcgtcatgca agatcgaaac agagtgacct tccgtatgtt ttgctaaggt aatcgttgat
    38101 tttccagaac cggacaaccc aaatacagcc atcgtatagg tctggtcatt actagcatat
    38161 tgtttcatcc caccgtggca ggcaataaag ccattgcgat ttcccaatgc ccaagcaagc
    38221 gtcaaagtcg ctttttttaa ttctccaaag taacgtaatc ctagcacagc cgctgtatta
    38281 tggagagcat caaacaaaat gagtccattt ggaaatgttt catgtgtcca ttcgggatca
    38341 caaaagatat aaagatctcc ctcatcaaag gaaacagact tttgataagt ctctaagatc
    38401 ttcgaattcg ctggctgaaa attcagcaaa taagaataca aattgttctc aaatccttct
    38461 ggaatcagca aatgactttg cacagaaaat tcttcagata ggccaacgat tacttttgta
    38521 tggtaaaact ggcgcttgcg actttgatac acagcttctc ttaaaatttt ctcgtatttg
    38581 ctttgttcct tgtctaagtc ctcaaagatc cgccgagcac ttgctgttct tcccacaatg
    38641 cttccatcat tgaatactag tgtcctaaca tcagctggta aatctagttc ttcagcatgt
    38701 gagattgtta aatctgtgat gatcgttcct ggactccctt ttgctagttg ataagctgtc
    38761 ttcctatcaa aaacttcatg aacattatta ccgtaaaatg tcgtttctac aatcgatcga
    38821 atactggata acagtggatt tccacttgtg atttcgttta attcgagact ctcttttgta
    38881 ctcatggctc ctcctcattc cctaaacaaa aaaacgtttt ctttattata cattattcga
    38941 gtttttattt gtactgctgc gctgtgggaa gcaaacgagt tatttttcac acaaaaaaac
    39001 cgagaacttg aataaacaag tttctcggtt tcatcatttt ccttttatcg gcttagtacc
    39061 agccgtttgc taaccagaat gttttagcag catcccatga accataacga gatgttacat
    39121 attgttctgc tacacgttct tgattggcag ctgaatagtc gccgtttaag tatgaagcat
    39181 ctaattgata acggccgatg taacgtccgt tagtagctgt gtatgaaccg cctgattctt
    39241 tttgtgcgat ccattctttt gcagagcttg aagttggcgc tgttgcagca gctggggcag
    39301 caggagctac ttcaactgtt tcaacaggtg caacgtatgt atgttcttgc gttgctgttt
    39361 cagttgtaga tgctgtattt tctgttgttt tgttttctgt tgttgctgaa gaatcatttg
    39421 aagttgggat tgttaattgt tcaccaacat aaatgcggtt gatgtttgcg atcgaatttt
    39481 tttcagcaat tgcatcgatc attgagttgt ctcctgcaaa tttttgtgag atcttagata
    39541 atgaatcacc tgattttact gtataaactt catcagcgtg agcatttgta gttcctacaa
    39601 acattgcagt agcaccagca gcaaaagttg tacctaaaac aattttctta aatgaattca
    39661 tattaaactc ctttttttct ccgtttttta ttctttcgac gctattaact ttatcattta
    39721 gaaatatttc ataggtaaaa gaaacatgac atttaatgac aaaataacga attatttaat
    39781 atttgtaaca tttaaacaaa tatttttttg atacaaaacc ataaaagcct tgttgtataa
    39841 gcaaagtaat cgtttttcta tgttttttta tttttgaatg aaaaacgcag attctgtaac
    39901 attcactgca ataatccata aaaaaaagca aaaaaatttt tgatttttat caaattctct
    39961 taaaaaaatg taaaaaatac aaaaaaacca gtaattgtta caacaattac tggacaaaaa
    40021 ctttgaataa tgttaactat ttttttattt taactttctc cgcaataatt tctgggcatg
    40081 ttccaattcg tttataacga cttcttctgt ttctttagct aatatttcat ctaatacatc
    40141 aagccatttt tccggttctt ttgttcctag acgtccaata gcccaagctg ctgttcctct
    40201 gatgacaggg cggacatctg ttaaacattc tgaaatctca ggcaatgccg ttcgatcacc
    40261 tagattagct aaagcaatca atgcgtttct ctgcaaaggt ttcttcccac gccatgaacc
    40321 agctaaatgc ccaaattgct gtttgaagtc tttattagac atcgaaagca ttggctttaa
    40381 ttttggatat atttcgtcta cttttggttc catctcttca tgaaaatgaa aatcttttcc
    40441 ttgattgtaa gggcagacta actggcagat atcacatcca taaatgacat ttcgcatttt
    40501 tttacgatat tcttccggca tcatcccttt tgtctgagtt tgataagaca aacatcgctg
    40561 ggcattcatt cttccgtcac caagcaatgc ttttgtcgga caagcagtca cgcagcgcat
    40621 acagtcaccg caaccaaatt ctcctggttt atcaggctca aatacaatat tagtaacgat
    40681 ctcaccaaga tagacaaatg aaccgaactc ttcagtgatc aacaatccgt ttcgtccaat
    40741 aaatcctaaa ccagctcgct gtgctacagc gacatcgatc agttctccag tatctacttg
    40801 cggagctaga cgccattcct cttctttttg ccatttttct gctcttgttt ggatgaattc
    40861 gatcaatcgg ttcaaacggt ctctgagtat atcatggtaa tcgatccccc aagaagcacg
    40921 agcaaactgc ccgcgttttt catccctagg cacttcttca tggatcctag taggatacgc
    40981 aagtgcaatg gaaatgatcg atttcggctg atcaaatgtc atttctggat aaagacgctc
    41041 atcgatattt ggatgttcaa agccagaagt atggccagct gctttttgtt cttccaacga
    41101 ttcttttaat gaatcaaaag gttccgccgt ggtgaacccg attttgtcaa ttcctaatcg
    41161 tttgctttct tgtatgattt cttcttttaa tgtcatggtc ttcctcgctt gctgttaacg
    41221 gctgtataac ccataatata gtttttcttt tttcagctgg acaaactgga tctgctgatc
    41281 ggcaatcttc ttttcttcca tccatttttt tcttgcagca aatacttccc aataatttgt
    41341 tgaaattaat tttcttttgt tatctaatgc attaaaaaaa ttcaatgaaa ctggttttgt
    41401 acttaacagt tcatggagcc ttacctcttc ccatggcgaa aactcagaca gatcgcggga
    41461 atacaatact tcttcataga gatttttttg ctgtgtgtac gtgaatgttt gcgggatttt
    41521 cccaggccta gcaatttcta ctagacgatt ataaaacata ttcattaatt tgctgttggc
    41581 aataaattga cttttataat aggccgactg gatctttttg attactcctt ctgctttgat
    41641 gactgaaaat aatgcaggcc atgctttgac ggttatttcg tcgttttgtt taactaatac
    41701 gccaggtgtg aagccgactg gagaaaggaa cacaaaataa ccgataccgg tattttcatc
    41761 taaaggctga aattcatcaa acaaccattt gcctatgtac agctcttcat ctggttctgt
    41821 tgtctcattt tgatttgcta tgaataattt agctaattct gcttcaagaa attgaaggtc
    41881 ttgatccttg tcggtatttt cctgctggct gatcaatcga aagacttctt ctttaatcgt
    41941 atatttatct ttacgtgtaa aattcatagc cacaccttcc ttccttactc taactataac
    42001 ggaatttctt caaaaaaggt atctgtacga cgaaaaacag cataattttt tttcatatct
    42061 cttataaaaa atgcaaggtc tgctcctcaa gctagacctt gcacttttca gctttctttt
    42121 gtttgtgaca aaccttcatg gatcgtttca atattccatt tcatcatctg atagtaagaa
    42181 tctccttgtt ctccttcttt tgctatggaa tcagtgaaca gtttatcata gattttcaaa
    42241 cccgtttctt ttgctacccg ttccatgctt cttgagtcta cactggtttc cacgaataaa
    42301 accggtactt cttttgctct tatctgatca atgatcgctt tcatttgatc aggcgtacct
    42361 tgactttctg tattgatctc ccatatataa gctgctggca aatcatatgc tcgtgaaaaa
    42421 tacttgaatg ccccttcact tgttactaat aattttttgt tctcttcgat agaagcaaaa
    42481 ctttccttcg cttgtgtatc taattctttt agtttttcca catatgcttc tgcatttttt
    42541 ttatagagtg tcgcattttc tgcatctttt tcagagaata tacgtgcgat ttcctccaca
    42601 tattttattc cgttagatag gtctagccaa gcatggggat ctgcttttgt atgttcttca
    42661 ccgctagtta aataaagagg ttctacattt ttgctaactg caaaataatc ttttccttct
    42721 tcttttttag ccgtttccat caagttatcg aaccagctgt tacctgtttc aagattcaaa
    42781 ccgttgtata aaataacatc tgcatcgctt gcctttttga tgtcttctgg tagtacttca
    42841 tattcatgcg gatctgttcc gactggtacg atactgtgga tatctatttg atctgttccg
    42901 acctcttttg ccatgtccgc caagatcgaa ttggtagcca cgactgacaa cttttcttta
    42961 cttccttcat ccgcttggtc agaagcctgc tttccgcaac cggctaatac caagaaacta
    43021 actgccaaga ttaaaaagag tgattttttt gttttcatct atctgcttcc tttctgaaat
    43081 aaaattcctt ttgttggaga aaataaaaaa gcaaggataa aaaatgcggt acatgctaac
    43141 acgatcgtag ctcctgatgg ccaattgtaa ctataactga aaaacacacc gacaactgca
    43201 cttagcatac cgattcctgc agctgtaatg atcattttca gtaaatggtt cgttagcaag
    43261 taagccgtgg cggctggtgt gatcaacatg gcaatcacca agattgttcc tactgtctgt
    43321 aaactgacta cagccactaa tgtcaaaaag aacatcaaaa gataatggat cagcgatgtg
    43381 ttcagcccat aagcttttgc cattgtcgga tcgaatgatg tgatcttcaa ttctttataa
    43441 aagaaaaaga caaatatcaa gacgattcca ctaacgagtg ctgtcagcaa caaatcgctt
    43501 tccctaacag ctaagacatt cccaaataaa atatgataca aatctgtcgc actctgggca
    43561 tatgaaatca agataatccc taatgcaaaa aaggagctaa agacaattcc aatcgctgta
    43621 tcatttttca atcggctccg ctgagtcacg aaaccaatca ctgctgctgt tagcatccca
    43681 aaagcagtgg ctccaaagat gtaactaaaa ccaaacatat aagaaatggc tacacctgga
    43741 agaactgcgt gagagatagc gtctcccatc aaagacatcc ctcgtaaaat aataaaagaa
    43801 ccgatgactc cagaagcaag tcctacaagc atggaagtga ccaaagcgta ttgcaggaat
    43861 tgataattca ttaatccatc aataaaggat tggatcattt tttctctcct ccttttacta
    43921 aatgtctgat gatctcacca taggccaatt gaaggttctt cgatgtaaag acttcttgta
    43981 ctggaccgga agcgatcagc tgtttattta aaagaataac ctcatcgaaa tattcttcta
    44041 ctttatgaag atcatgatgg acgatcaaaa tcgtttttcc tgaattcttc aattcctgca
    44101 agatgtcaaa gatctttcgt tcacttaacg catcaatccc tacgaatggt tcatctaaaa
    44161 agatccattc tgctccttgg gctagagctc ttgcaataaa aactctctga agctgtccac
    44221 ccgatagttc gctgatctgt cttttggcat attcttccat ccctactttt ttcaaagctt
    44281 gtcttgcacg ttctttttct tttttcccag gtctttgtcc aattcgtaaa gatggatatg
    44341 ttcctaaaag tacaacgcct aatacatcaa ttggaaagga aagatccaat tcacttcgct
    44401 gttccacgta ggctattttt ttacggactg agtttaccga ctgtccagaa aaggtgactt
    44461 taccagtagt agctggtatc aactctagca aagatttcat aaatgttgat tttcctgcac
    44521 cgtttggtcc gataataccg gtaatttttt gtggatttat cgtcaagttg atagttttca
    44581 aaacagtttt cccttgataa gcggctgaaa ggtcttgaat tacaatggcc gtacgttcca
    44641 aatcttacac tcctttttag gtttacctaa ctttttattt aaatatagtt taactaaaat
    44701 ggaaagcatt ttcaagtaga atgatgaaaa agtttttttc gaattttcct cgcattttat
    44761 gaaaattttc tgtagaatca catcaagagt tcaataaggc taacctaata atgaaaaaca
    44821 tgtgttgaaa cgtttgatta ttttttcttg ttgactcaac aacgaaagga gtttttgtat
    44881 ggaagaagaa aagttaactc gaagtcttag tgcccgtcat atccaaatga tcgcactagg
    44941 tggaacgatc ggtgtcggtc tgtttatggg tgcctcctca accatacgtt ggacagggcc
    45001 ctcagtgatg ggagcctatg cgattgcagg attctttttg tatttgatta tgcgtgcttt
    45061 aggcgaaatg ctttacgttg atccttcgac tggttctttt gcaaattacg cgagcgagta
    45121 catccatcct gtggctggct acttgaccgc ttggagtaat atttttcaat atattgtcgt
    45181 aggaataagt gaagtgattg ctgtaggatc ttatatgaat tattggtggc ctgatttgcc
    45241 ggcaattatt cccggaatca ttgtcgtctt gtttcttatg ctggcaaatc ttatttctgt
    45301 caaggcgttt ggcgaattag aattttggtt ttcgatcatc aaagtcataa cgatcatttt
    45361 gatgatcatt gcaggtcttg gggtaatctt atttggattt ggtaatcatg gtcaggcagt
    45421 agggatttca aatctttgga aaaatggtgg attcttcact ggaggcgtca aaggattttt
    45481 ctttgcatta tcgatcgttg ttgcttccta tcaaggaatc gaactgatcg gaatgactgc
    45541 tggtgaagca gagaatccta aaaagacgat cattgaagct gtccagtcca ctatcggtcg
    45601 aatcttgatt ttttatattg gtgctatttt tatcattgtg agtatctatc cgtggaatca
    45661 attgagtgag attggttcac cttttgtaca aactttttct aaagtcggca ttacatttgc
    45721 tgcaggactg attaattttg tcgtgattac agcggcatta tcaggttgca attcagggat
    45781 tttcagcgca agtcgtatgg tctatacact tgccataaat ggaaagatgt ctaaaaaatt
    45841 tctgaaacta tctcgtcacg gtgcgccttt ttatcctgtc gtagcaatct caggtggaat
    45901 cttaattggt ctgatcttaa attatcttct accaatgttc atcaaccagt cagaaaatat
    45961 tttcgttttc gtatacagct caagtatttt gcctggtatg gttccttggg tagtgatttt
    46021 gatcagcgag attcgcttca aaaagaagca cgcagataaa atgcatgatc atccttttaa
    46081 aatgccacta tctccttata cgaattatgt gacacttgct tttttagcta tcgtattgat
    46141 tttcatgttt atcaatcctg aaacgagaat ctcattgatt attggactcg ttttcttgct
    46201 ttacatgacg atccattact ttgtacgcga aaaaagaacc ggaaaataaa aaaagaacga
    46261 agcttcacct tagtggaagc ttcgttcttt tttattgctt ttatcaattc aattttagcg
    46321 tctcaccggg agtcaggaaa taattctcca tgctcatccc attcagcgac aagatcgttt
    46381 ctactggtac gccagttcgt tcggctattt gatttggacc ttctccttcc aaaactacgg
    46441 ttgtcgcagc ctgtgaagtc gcgctgttgg tattagtttc agaggaatct gttgtgtctt
    46501 gtgttgttcg agcttgcatt tcagaagctt ctaccgactc tgctgtctca gaatcagaag
    46561 atgttgtgtc ttgtgtgctt gttgactctg cttgaagaga ggcgctagtc tgcaaataaa
    46621 tatcggaaat cttagcgaca tgattcgtat aattagccga taattgattg atcaaagtat
    46681 ctaagtctac accgtcttta ttttctgctg cctgatacgc tgcacgtaat tttctgatcc
    46741 cttcgtcgga gattgcttga agctcacgtg ctttttggtt agcaactgct gataaaccag
    46801 ctattccctc ttgatttccc tgaatttctg tctggtattc ttcaatcaat gcaggcgtct
    46861 tttcttcgat ctttttcgaa taatcattta cgattgcttg aagttgctct ggcaaaccat
    46921 ttgctgtttt ttcttcagaa gtttgtgtct cttttgtttt agttgatgac tcacttgttt
    46981 gtttcgtctc tgttttcttt gtcgttgttt ccgttatggt cgtacttttc gcttctgacg
    47041 aattttttcc atgaaaatat agacccgcaa ctcctcctgc tatgatcaaa aacacggcaa
    47101 ctgctgcccc aatcatgatc atccgcttac gagctgcctg tttttgctgt cttcttcggg
    47161 tcatccgaac attttctccc cactcatttt catcatacat ttttttcacc accaattttt
    47221 atgtataata gcgttatcaa acgcttcata ttcttattgt agcaaataat tgtcgctgtg
    47281 cacattttta tctttgttat ttataagaaa atttcaccag ttgagatgat tccaagattg
    47341 tccgtcgatt tctccttgca gctgcattgt tcgttcgtct atctcagcca tcagtttctt
    47401 tatttcatat aagagcgcac ggtcttgata ttctgatttt tcgcttaatt catctaattg
    47461 ttggatcagc caatcatttg tcataatgaa gttcctttca tttcttgcag tgtaaaggtc
    47521 aagtcttcga tctgctcttt tgcctcagtc agtgcttcta cgatatatgc ttgtttttca
    47581 gattcttctt cctgcatttt ctgattttcc tgtactcttt gaataaacca gtcaatccgc
    47641 tgagtcagcg atggtttgcc ttccaatgag agatactgct gataagcaat tagcttctcc
    47701 caacgttttt cctgggataa atacataaat tgtgctaaaa cgaatggcgg aagataggtc
    47761 atatggaatt tatttgcgat tcgctgatac ggcctcaaaa attcggaaat cgtatattct
    47821 tcttttcctc cagcttggta ttctttttcc gccacacctg ttgtcaatac gattcctagt
    47881 tctttccctt ttaatacatg tgctgctcgt tccaagacat tatcttgcca aatttttaaa
    47941 tgagcaggag aactatacca gtaaaacgga aactggaaaa tgatccgatc atgctgggcc
    48001 aagagctgta gttcagtctc tatatctatt tttccgtctg gataacttga ttccaaatga
    48061 tgccaagtag ctggtaaacc agcagaagct tctttgaaaa attgctgatt taaagattct
    48121 tcgatcgttg gatggctaat gatgataagt gtacgcatcc cttttcctcc tttttagtct
    48181 tcgctttaca gtgtagcata accgccacaa gtttcttttg ccgatgcttg tcattttaac
    48241 cagactaatc aggttgtcca agaaactgcg gtttgttttt ccaactgttt tttcaaggta
    48301 tccaaagcaa tattcttaaa attttcgttt ttcatacgtt tacgatagtt cgtagccgtt
    48361 tctccggtac tctttttgaa cattcggcta aatacgacta gactattgaa ccctacttga
    48421 taggcaatac tttccacgga ttcatccgtc agagaaagaa gaaacgcccc tcgattgatc
    48481 cgtaccccga tcaaatattc cttgatactg gtacccatat gatttttgaa tactcgcgac
    48541 aaatggctcc gattgaccgc taaatgctgg gcgatttcct caacagacaa tttttcagca
    48601 taatgtgcct cgatgtattt gactgtttca acagctaaag aggaatgaac cttttgtaca
    48661 ccaccgctga cctttccgcc atcttttaaa aggactgata aaaaacggta ggttaatgct
    48721 gttaactgta attcattttc caaggtttct tccgtatctt tcatgcattc taaaataatg
    48781 tcgatatatt tttgtatgtc agaagagacc atcgtgtatt ggtcttctct gaaaagcgac
    48841 tgccgaatga tttcttctgc agcactccca ccaaatgaaa gccagcaata catccacgga
    48901 tcttctccat ctgataagta aaacgtcgag tctcctggac gaatcaagaa cagatcacct
    48961 tttttcaatt ggaattgttg atttttcaca tgataagatc ctttgccttc catcacgaca
    49021 tgcaggatgt aatcattgcg aatagcagga ccaaaagaat gaaacggcat cgttttagag
    49081 aaaccacaaa aatcaaaata caattctttt tctacttgtt gatgttcctt ttttaaaaaa
    49141 atcgattgct ccacgtctat ccctccttac tcctttagta taatgcaaca aaaagttaaa
    49201 taaaagtcac agaaatatat taaaaaggaa gcgatttctt gttaagttta agtcattaaa
    49261 agatctttgt tattcgttgt aaccggttta cttagtatta tatattgaac aggagaggaa
    49321 tacagattat gaaaagcaaa atgatccaac gtgtgtccta cgctttaggc gcttttggac
    49381 acgacacatt ctatgttaca ttaagcactt attttatggt attcgtgaca agccagatgt
    49441 tcgcaggaac agataaggca acgaatgcaa aaatgattgc tacagttaca agcttagttg
    49501 taggtatccg cttagttgaa attatttttg atcctttgat tggtggcatc atcgataata
    49561 ctcgtacaaa atacggtaaa ttcaaaccat ggttagttat cggcggcgtt gttagttccg
    49621 tactcttggt agcaatcttt accaatttct ttggcttagc tactcataat acgactttat
    49681 ttatcatatt atttgcaatc gttttcatct tattggatag tttttattca tttaaggata
    49741 tcgctttttg gtcaatgatt ccagctttga gtacggaaac aaaggaacgt gaaaaatttg
    49801 ctacgtttgc tcgtttcggc tcttctctag gtgcaaatgg tactactcta gtcgttgtcc
    49861 ctatcgttac tttctttacc tatcttgtta ctcataaaca tattgaaggc gcttcaggct
    49921 ggttctggtt cggtgtgatt gctgctgtta tttcaggcgg tactgcgatt atcactgcct
    49981 tgggcacaaa agaagtcgat actgcgatcc gtcagcaaaa tgaaaaagct gggatcaaag
    50041 atgtgttcaa agcagttgct caaaatgatc agttgatgtg gcttgccctt gcttatatcg
    50101 cttatgcgat tgccaatgta gcaacaactg ccgtattatt ctacttcttc aaatatgtac
    50161 ttggccaacc aactgaattt tggatcgttg gtctagttgc tgccttactt ggtttagtag
    50221 ctgttccact attcccaatg cttacacgcg tcatctctcg tcgctacgtt taccttggag
    50281 ggatcgcaat gatgatttct tcttactttt tctttacgat cgcaggttca agtttgccaa
    50341 tcgttatcat cgggctagta ttgttctact tccctcaaca attgattttc ttatccgctt
    50401 tgatgacgat cacagactct gttgaatatg gtcaatggaa aaatggtatc cgtaacgaag
    50461 ctgttactct atcaattcgc cctttactag ataaaatcgc tggtgctttg tctaacggga
    50521 tcgtagggtt tgtcgctatc gcttctggga tgactggtaa tgctactgct gctgatatca
    50581 ctgctcatgg cgtaacgact ttcaaagctt atgcattcta tgctcctgct gctttgatga
    50641 ttttctccgc tattattttt gcttggaaga ttacattgac agagaaaaaa catgcacaaa
    50701 tcgttgagaa attggaaaac aaattggctc cagctgatac aatggaagat gaacttcacg
    50761 atgcagtagt tccttcccat taagaaagga tcttgaaaat gaagattaca gaaaaagatt
    50821 ttggccaagg ttatcacttg ataaccttgg agaacaaaaa caagctagca ctttctatct
    50881 ctgatttagg tgctagaatc gtcagtttaa aatcaaatga tcgagaatta gttttgggat
    50941 ttgacaccgc tgaagaatat atcgaaaaag atccgtatat cggtgcttct atcggtcgca
    51001 ccgcagggag aatcgaaaat ggccgctttt ctctcaatgg aaaaacttac caattagcca
    51061 cagatccaaa aactggacat aatctgcatg gtggtgctcc tggatttgaa ttaaaaaaat
    51121 ggtcttatgt cattttgaat ggcgaaaatg aagcttctgt catttttact actacaagtc
    51181 ccgacggaga acatggtttt ccaggtacaa tggatgtgga aatccgctat actttgacaa
    51241 aagataatat ctggcgagtg acctctcgcg gcaccagtga ccaagatact ttattcaatc
    51301 cgacaaatca tgtttacttc aacttgacgg gagatgcttc tcagtcaatc gatcaacatg
    51361 agctttggct caatagcgaa gcttatgctc ctttgcgaac agatagtatt cctatagggg
    51421 taaaagaaaa tgctgcagga agtgctttcg attttcaaat acctaaaaaa ttagcgtccg
    51481 tttttgctag tgatttggat caaaaaaatc ttgttgacgg aatcgatcat ccatttttct
    51541 taaaagaaac cggcttgggt aaagaagccg ctcgcttgac tagccccgat aaaagaatcc
    51601 aagtagatat tgctacagat gcttctagtg tggttatttt cactgcaaat ttcggcacag
    51661 aaacaccaga aatgcgcaac cgaaaactgg cacatcacgg tggcatcaca tttgagactc
    51721 aaacagctcc aggtgcagag cgcttctcag catttggttc gattcattta aaagccggat
    51781 cagtatttga aacagtaaca gaattcaaaa tcaaaacaag aaaggaataa ctcatcatgg
    51841 aaatcaaaag aagcttaaac acaaaatttg ccgaaacatt cggacctaaa aaaactacac
    51901 aatacttctc accaggacgc atcaatttga ttggtgaaca cacagattac aatggaggcc
    51961 atgtcttccc cgcttccatc acttatggaa cgcaaggtgt agcagcacct cgagacgata
    52021 ataaaatatt agtttattcc acaaactttg acgatatcgg tgtcattagt tttactttag
    52081 atgagctaga atatgataaa aaagcaaact gggcaaatta cgtaaaagga atggtcctta
    52141 aattaaaaga agctggacac tcaatcgatc atgggtttga gttattagtg gaaggaacaa
    52201 tccctaatgg tgcaggactt tccagtagcg cttcattaga attattagta ggtgttgtat
    52261 tagaagatct gtttgattta aaaacagatc gcttggaact agtccaaaca ggtaaaaaag
    52321 tagaaaatga attcatcggt gtcaattcag gtatcatgga tcagtttgcc atcggcttcg
    52381 gtgagctaga tcatgcaatc ttattagata caaatacgct gaaatacgaa atggttccag
    52441 tgaaactaga tggttatgca atcgtcatca tgaatacgaa taagcggcgg gaattggcag
    52501 attcaaaata caatgaacgc cgtagcgaat gcgaagaagc cttggcacgt ttgcaaaaaa
    52561 ctttgcctat ctcttcttta ggagacttag atgaagaaga atttgaatca actattgacc
    52621 aaatcggcga tgatacattg atacgcagag ctcgccatgc cgtttctgaa aatcagcgga
    52681 ctttgaaggc aaaagctgaa ttagaagctg ggaacttaga agcatttggt caactgttaa
    52741 atgattctca ccactctctt cgctatgatt atgaagtaac tgggatcgaa ttagatacac
    52801 tagtagatgc tgctcaaaaa caagaaggtg tcttaggtgc acgaatgaca ggagctggat
    52861 ttggtggctg tgcgattgct cttgtcaaag aagaaaatat acctgccttc aaaaacaatg
    52921 tctatgatga atacatgaaa gttgtcggct atgctccgga attttatgtt gcacacattg
    52981 gaaatgggac aacaaagatc gatccagaag ctgttcatgt ttgataaaaa aatcaacgat
    53041 ctcagctaaa aacaaataga taaaaataac ctctcagcaa tttccaaatg tgagcctttt
    53101 gctcgtattt gaaaattgct gttttttatt gacacggaaa gagaacgtgt gttctaattg
    53161 tgttgaagag gtgattgtta tgtgggcgaa tcaaaatccg gtatttgttt atgaaaaaga
    53221 accttcaaga gatattttat gtattgactg caaatctttt tacgcctccg tagagtgcgt
    53281 tgaaaaggat cttgatcccc ttacaactaa attagtagtc atgtcctatc cgtccgattc
    53341 gacagaaaca cggggtagcg gattaatctt ggcttccagt cctgcagcaa aaaaagctta
    53401 cggcatcacc aatatcagcc gtgccagaga tcttcccttc ccctatccaa gtgatttata
    53461 tattgttgcc ccaaggatgg cctattatat ggaaaagaac agagaaatca attctatcta
    53521 taaaaaatat gcagacgaag cgaaccatca tgtctattcc gtcgatgaaa gcttccttga
    53581 tgtaacaaat agcatggcac tctttggtaa aacaaatgcg tacgacatgg ctaaactgat
    53641 ccataaagat gtgtttgagc agaccggaat ctacacgact ataggaattg gcgataaccc
    53701 gctacttgct aaactagcct tagacaatgg ctcaaaagac ggaaagcaaa tgtttgctga
    53761 atggcgttat gaagatgtac cagaaaagtt atggaaaatc tcagatatca ctgacttttg
    53821 gggaatcggc aaacgaacag caaaacgtct gaaacaaatg ggtatacatt ctgtttatga
    53881 tttagctcac gcggattatt atcacttgaa aagcaagcta ggggtcatcg gtactcagct
    53941 ttatgcccat gcttggggca tcgatcgaag ttttttggga caagaatata caccaaaatc
    54001 aaaaagtatc ggaaatagtc aaatcctaga tagagattat acaagacgag aagaaatcga
    54061 gatcgttatc aaagaaatgg ccgaccaagt cggcactcgc ttgagacgat ctgcagcaaa
    54121 aacacaagta gtcagcttat gggtaggata ctctttaggc tatcttgatc caaatggcaa
    54181 gaccgggttt caccagcaaa tgaaaatcga agcgacaaat gctagcagag atctagcaga
    54241 tgctttattg accattttcc accagcatta ccactaccag gatattcggc gtgtaggcgt
    54301 gaactgttcc gacctcgtat acgcgacagg tttacagctt aacctttttg aagatcctga
    54361 aaagcagata aatgaagcga aagttgattt tgttgtcgat acgattagaa aaaaatacgg
    54421 ctttcaatca atcatccatg cgcatagtct cttgcaagga ggacgcgcca tcgcacgtag
    54481 ttctctcgtt ggcgggcatg caggtggtat gagtggatta gaaggtggaa aagatgagac
    54541 ggacagcaaa aaaattcatt gactataacg agtatcgaga tcggccattt ggattaaaat
    54601 gggggactgc ttttgcgatg gaagaactag tcaacggtat caaaaaaatg aagaagaagc
    54661 acgcaaacag cctcttccta aacaacaaat gacattgcaa gaaatcgata gtatactgac
    54721 agaagccttt ttatctcgta aagcagtaat cattcagctc aatttaaaag atgaatttgg
    54781 aagactcttg gatgaggtcg aagggcactt cattggtgaa gcctatgaag attactttat
    54841 gattgaccat cagccgatat tgtgggaaga cgtacggtat attgagttaa aggaaacaaa
    54901 aaaatggttt gtgacatgag aggttgtgac agaagtgatc aacttcaaaa aataagaaag
    54961 gatttttcga aaattgcttc ttaaattttt gtggaatttt ggcttatttt tcgaagaagc
    55021 aacttctgga acaacgtata ttagatatca gaggttgtga aaaagtcgct tagttttgag
    55081 taacaagcca aggcgctgat ttcacaacct ctgtctatct atccatctat tcggtaagat
    55141 tcatgcatga cgtcttcttt atttagtatg tagagccctt tttcttctga ccattcaaca
    55201 taaatcagct gttttacatc tgcatagcct tctttcttca agttctccat aagccatgct
    55261 tcagtcaatt gattggactg aagcacttta tgctgaattt gcccttcatc tacaagcagg
    55321 atcgataaag ctttgtcttc atctgatttt ttcaatacac tcatttgacc ggcattctct
    55381 aggataacat gtttggcatt ttcaagaaaa aagcattctt gctgtcttaa gattgctcgc
    55441 aactgctcca tctcgatatg gttatttgtc aactctgtca tgttgatgac gccgtctttg
    55501 attagaacag atggctcgcc tttgacccaa cgattgacct tttcattttt ttggacgata
    55561 cgttcgatac cataaatcat tactgcccaa agcgcaatgg caaataggac atgccctaca
    55621 tggacattgt catcataggt tgattcttct aagatcccac ctaaaacaag cgtatagact
    55681 aaatcaaacg gtgtgatttc tgacatggat ttcttcccaa gcaaacgtac cactaataat
    55741 aaaccgatca acccgaacac cagtttcatt gtaattgaaa aaatcatttt ttctccccct
    55801 aactatctgt taattaaatt atatatgctt tctcacgaac acgcatggaa tatacaagga
    55861 agaaatgtat ccttttacta aaaaaaggac tgtgacactg tagtgacccc caaaagttag
    55921 acttttttgg agtggagaaa tccactcctt ttttttatgc tctaaaatga tatttttaca
    55981 caaccgttac ggttgtttta cgaaattgga cgagactttg ccagtttaat ttctgtttta
    56041 tccgttcatt attgtagtaa tagatatagc tatcgatggc tgattttaat tcctcgaaac
    56101 agttataaac tttcccgtga aaaatctctt gttttaataa gccaaaaaaa ttctccataa
    56161 gtgaattatc taagcagttc cctttccgag acatgctttg aaagattttg tactccttca
    56221 atttgtttct ataagctttc atttgatacg cccaaccttg atctgagtga aacgtacgac
    56281 gatagggaca atcgttagtg gtctggatag cttcctccaa accttccatt accgctaatg
    56341 cattgggctt ttcagagata cgataggata aaatctcact attgaacata tccataaaag
    56401 gatctagata caatttcttt tgacggataa tgcctttggc atccacttca tggtatttaa
    56461 attcagttgt atccgtcgtg attttctgat ggcagatact ggtgtagaaa cgacgatgga
    56521 tccgattttt ggctactgct ccaacttttc ctcgataaga attgtagcga cgtgatttac
    56581 gcgtgtatgc cgttactttt attcctagct tcttgatcaa gcgctgaact ttctttttat
    56641 tgatagagaa accgcggttt cttagttcat tggtcatccg taaacagcca taatccttgt
    56701 gcttctcccg aattttaagc atttccgctt caatctcttg atctggattt ttacggtcca
    56761 atcgcctttg ccatccaaat aatcatgaac gatctttaat ttaagttcaa aagtatattt
    56821 aaccataaaa aataccgacc tccaaaagtt agattttttg gtctaacttt tgggggtcgg
    56881 tacacaaatc gtgtcacagt cccttttttg aaaataaacg gtgttcaaaa gcttgcatct
    56941 gcggtaataa gtccagccaa gttaaaaaca taagaagctg tttttacttg gctgttctta
    57001 ttacttgatg caaggcagct ttttcacaac ctcttttcaa atatttcgtt ttcttattct
    57061 acaaatggtt cttctcctaa cgcttgttga gcggctagat tcaacatgct ccattgtcgg
    57121 tcaaagcctg gctggaagaa gaagtcagct tctgctagtt cttctaaagt cagtttgttt
    57181 tggatcgcta gtgccaatac atttccttga cctgtaacat cataggtaga taatactgct
    57241 cctcctagca attgatgggt cattggatcc gagaataatt ggatggacac ttttggattt
    57301 ccttgttctt ctggtacata ttttggtcgt aacgtatctt cataataaga cactcgtaca
    57361 tctactcctg cttttgctgc tgtaaagcta ttcaatccgc ttgctgcaaa atgatagtca
    57421 aagacactta atgcagagga acctacgact ccgccgaacg gtttgtttgg tacttcttca
    57481 aaaagatgtt ttactacata acgtgcttct ctacgtgcaa cagtcgctaa agcgatcggc
    57541 atttttttgc gtgctgggat agaataagca agtgtagcat ctcctactgc atacacatct
    57601 ggaagattcg tttgcaagta ttcatttgtt tggatccagc cacgttcatc taagtcgacg
    57661 atccctttta accattctgt atttgccttc acaccggcag cttgaatgac tagatctgct
    57721 gggatttctt tttcacttgt tttgattgcc tcaacttttc cgttaccagt aaaagcttcg
    57781 atttttgcat ttgtcaaaac ttcaataccg ttttcattta ggtgttgttc taaaatatct
    57841 gtcatctcag catctaaata agtgcctaaa ggtctatcga tcacatcaag caatacgact
    57901 tctttcccag cttttcggct tgcttctgct gcttcgatcc caatgtaacc cgcacctacg
    57961 acagcgattt ttttaatagc cggatcattt aatttttctt tgattttggt tgcccaattg
    58021 tatccacgca tcaagtagac attttctaga tctgctcctg gtactggcag attgtttggt
    58081 ttgacaccag aactcaaaat caatttgtca taaggatatt cttttgtttc gttatctgat
    58141 gcgctagtaa ccgttactgt ttttttatcg gcatcgatcg tttttacttc gtgattattt
    58201 aaaatatgaa cattggattg cggaaagttt tctggtctga aattacgtac atcatttaca
    58261 tctgttacct tgtcttctaa atacagctcc ataccacatg acatgaagga aatatagtct
    58321 cctgcttcaa atagcgtgat atctacattt tcaccgtatc gtgtcaatag ttccaagatc
    58381 gattgatgcc ctccatgaga tgcacctaca atgacaactt tgattttttc cattgatgaa
    58441 acctccttga atattctttt aaaatcattc taaacaattt aaacttaaca ttacattagt
    58501 tatgaatcaa aagaaacgcg ttcatttgaa ctaaatttaa aaaacaatcg tctccttgca
    58561 gaatataccg caaaattaac gattgttttt ttgataaaat ctatgaatca ctgttctgtt
    58621 aaaaagtctt tgatccgttt gcaggcctca tgtaattttt ccatgctgct agcataagaa
    58681 atccggatat aaccttctcc ttctgggcca aatgcaattc ctgggataca cgcaactttt
    58741 gcctgttccg ctaattctac acaaaactgc caagagtcag tttgaatggc agctgggagt
    58801 ttgcaaaaca agtaaaatgc accgtttggc tgggtcactt caaatcctaa aggcgccaat
    58861 tgctggacca gatagtctct tcgtgtttga tattgctctt tcatattctc gctatctttc
    58921 accccattta ttagcgcttc agccgcagct ttttgcgaca tcgttgtagc ggcagtcacc
    58981 agatattgat ggactttaat tagttcgtca ataagggctt tttgagcaaa aataaagccc
    59041 actcgccaac cagtcatcgc atgtgacttg gataacccgc ttatcacgat tgtttgttct
    59101 ggaagataag tagctatgga catatgcgtt ccactataag tcaattcagc atatacttca
    59161 tcacttataa caaataccgg atattttttt aaaacctcag cgattgcttt caattgtttt
    59221 gcagacaatg tcgtcccagt aggattgtta ggatagttta aaatgactgc tttgacagct
    59281 gatccatatt gttcaaatgc tcgttcaaat tgttccggct gacagacaaa ccctgtgtca
    59341 gaagtatcta tcgggatcaa ttcagcacca gctagttcca ctaatggctg atatcctgaa
    59401 taagcaggcg ctggaataag aaccttgtct ccttcttcca aaacagataa caacgcagag
    59461 gcaatcgctt ccgttgcacc aactgtcgtc aaaacttccg tttgcggatc ataagttaat
    59521 ccataacgct gttgctgaaa tatacaagcc gcttcccgca gttcctctaa tcctctcatt
    59581 ccggtatagt gagaaaagtc ttcttcaatc gctgctattc ctgcttgctt gacatgttca
    59641 ggagttggaa aatccggttc tcccagggtg agtttgatca catctggtat cgacgatatt
    59701 tgctgatcga attgtcgtat ttttgatact tctattctag aaagcctagg actaaatcga
    59761 ttggataaat tcatcattat ttactcgctc ctcttttgaa ctgctatcga tttttacaag
    59821 aagattttct gtaaaaagaa tcgttttgta ccattctaca ccattttcta aaacatccat
    59881 atcaaaatcg aacgtcggat catgtaaagc aggggtatca ccgacaccta aaaagaaaaa
    59941 tacacatgga tattgttgcg tatatatgcc aaaatcttcg gcttgaagaa ctggagcatc
    60001 taattcatgt agtttgtttg aatctaacag tgctgcatat aagcctctat ggttgattac
    60061 agctggatag ccgtcattat agcgaaaaga aatagtagct gtagagtgaa actgttctgc
    60121 taaatggtct aatcccctct tcaaataatt ttgcatatct gaactgtaag aacggatact
    60181 tccggataca ataacttctc cagctaaaac atttcggatc gttccacctt ggatttggcc
    60241 aaatttcatt agatgattcc actctgccgg taattgccgg tcaaaatcat aaacattctt
    60301 caaaaatcgt acagctgcct ccagactatc gattcctttt tcactagaag caatatgtgc
    60361 agactggcct ttaatgataa tgtctgtttc actgctttgt gccatcaaag gtcctggtcg
    60421 agagaaaact tctcccttag ctagtccagg ccatagatga aagccaaata ttgcttgtac
    60481 ttcatattta tccaacaatc ctgactgaat aacgctttgt gcgccaccgg aaatttcttc
    60541 tgatggctga tagatcagta ctacattata aataagatcc tcaatgtgtt tagttataaa
    60601 gtcagtcaac cctaaaagca tcgccatatg tccgtcatga ccacatgcat gcatataacc
    60661 ttcatgctta gaagcaaaag agagattcgt ttcttctttg actggcagtg catcgatatc
    60721 tgttcgaaaa gcaatcgttt cttcttgctg attatcaaaa taaaggagta gtcctgtttc
    60781 gccgatttca tggataacgg cctcgctgtt ttttacttgt tcatataaat atttttttgt
    60841 cttgaattca tgaaacccga tttcaggaat ttgatggagt gccattcgat attctttcag
    60901 catccgtatt caccatccct tcatagatac ccttcactac tgtttcatat tgattattcg
    60961 gtacaccgat gatcagattc aactcctgtg ctccttgtga taagatcgat gtgcgaattt
    61021 ctaatttgtt caatatcgat aacactttcc cagataatcc aatcaattct ttatgcggac
    61081 ccccaacgac agagatcaaa gctaagtctt cgatcacgac gatttcttcc acgccaagtg
    61141 tttcttttaa ttctttcgtg atgagaaata acttatcggc aatcgcttct gctgagacga
    61201 tcactccgat attgtcgatc cctgaaggaa tatgttcgat tgatatctca tgtttagcaa
    61261 aaatgctcat tgctttccag ataaacccga tttcatcgga catatgacgt ttgaataaag
    61321 tgatggaaag aaaatccttg cgtccagcta ttcctgtcag tccattttcc ttttctattt
    61381 cgtgattcga tatttttgtc ccttgagcga aaggatcatt ggtatttttt atttggatgg
    61441 ggatatcagc ctcttgaact gggaaaacag ctgcttcatg aagaacgtta gcccccatat
    61501 aagccatctc tctcagttct ctaaaagaga tttcctcgat gattttagga tgatcgatga
    61561 ttcgcggatc agccatcatg attcctgaaa catccgtcca attctcataa ctttccgctt
    61621 gcaacatctt cgccagtatc gcgccggtaa tgtcgcttcc cccacggccc aataattttt
    61681 cttttcctgc agggttcgcc ccgtaaaacc ctggaacaac cattttcgga tatcttttaa
    61741 atgcttttgt gatttcctgt gctgtttttt cctgatcgat tttcccatca tagtcaaaga
    61801 aaatcaggtc ttttgcgtca ataaactggt aaccaagata ctcagccatc agttgagcag
    61861 tcagatattc acctctactt actaaataat cttcagttat cttttcgtct tccagttgtt
    61921 tctgtatgcg tgctagttca tcttcaatag gtaactgcag ggcaagaaca tctcttactt
    61981 gaatgaaacg atcacaaatc cttttccaaa ggggtgtcca atcaacatga tgctgaaggt
    62041 aagcataaat caaataaagt aagtctgtta ctttgtcatc atctgacgta cgtttgccta
    62101 aagcagaaac aacgatcact tggcgattgg gatctgaaag aacaattgta cggacttttt
    62161 tgaattgctc ttcatgagac atcgatgttc cgccgaattt cgctactttc agcgtattac
    62221 tcatcttgcc acctccgcta ttttctgcat taaagctgca gcaatctgta cggcattcgc
    62281 agcggctcct ttgcgtatgt tatcggcagt cgtatagaac aacaatccgt tctctaaaga
    62341 agtgtctttt ctgatcctcc caacataaac catatctgtt cctctagcaa gaatgctcgt
    62401 cggatattta tgtgctgcta gatcatcttc taattgaatc cctggaaact ggctgagaca
    62461 ctctctaatt tcttccgtcg taaactcttt ttgcagttga actgccacag agactccatg
    62521 tccattttcg attggcacac gtacgcaggt tgctgatact ggcaaagcag gctgatgcag
    62581 aatcttacgg gtctcattta tcattttctg ttcttctttt gtatacccat tttccaaagg
    62641 ctgatcgatt tccggaatca ccgtttggct aatattataa ggatacaaaa ctggttcctc
    62701 gtcattttgc gtacgatgaa gatcttcaat gcctttttgc ccggaaccag aaactgcttg
    62761 ataggtcgaa taattgactc gctggatacc aaaggcttct tgtaaagctt taagcggaag
    62821 taccgcttga atggttgaac aatttggatt tgcaatcagc cgattcaatg tatagtcttc
    62881 cagattgacc tctggaacga ttaatggaat atccgaatct tcccgccatg ctgaggaatt
    62941 atctatgaca aatagtccct gacttcgtgc gattggcgca aactctttgg atacagaagc
    63001 acctgcagaa aatagcgcta aatcatatcc ttcaaatgaa gtttctgtca attcctgtac
    63061 agtgtgtttc tttttcttga atacacaaac tttaccggct gaacgttttg aagctaataa
    63121 tttcaatcgt cctactggaa aatcatattc ttctaacact ttgagcatcg tttggccgac
    63181 taatccggtt gcccccacaa tacaggtatc tatttcgcgc atttttctcc atctcctcta
    63241 taattcgcgt aacgcagcaa tcaatgctgt attttctttt gtctgatcat cacttatttt
    63301 taatacacgt gcaggtattc caccgacaac agtttctgct gccacatctt ctaaaaccac
    63361 tgctcctgct gccacgactg catcttttcc gatatggaca ccttcaacaa tcactgcatt
    63421 cgcacctacc agtacgccgt cttctacgat aaccggtttg gccgatgctg gttcgatcac
    63481 acctgctaag acagctcctg caccaatatg gcagtttttg cccactgtcg ctcgtccacc
    63541 taagacagca cccatatcaa tcatcgtgtt ttcaccgatt actgcaccaa tattgataat
    63601 cgctcccatc atgatcacgg cattgttgcc gattgacact tgatctctga taatagcacc
    63661 tggttcgata cgagcattaa tttttttaat atctagcaaa ggaactgcgc tgtatcttgc
    63721 agcagtttcg atttcgattt caatgatttt ttctgattca gcttctaaaa ccggagcaat
    63781 cgtctcatag tcaccaaaaa caacgaagct gcttccttca ccaaaaactt tactttcttt
    63841 aaattcgatt ggctcggtta cattcagata gactttcaca ggcgtctttt tagatgccgt
    63901 ttgaatgtag cggatgattt cttgagcttc cacgtttttt acaccccttt gtccattaat
    63961 aaatcttcta atttgtaata acctggtgac tgatctttca accagtccgc tgcttctact
    64021 gcgcctgcag caaagattcg attagaaaaa gattcatgtt tgatcgtaaa tatttcatca
    64081 gtagcagcaa acaatacatc atgttcacca ggtaaagaac ctgcacgaat actgtgtaca
    64141 ccaatttggt tttcttctct ttttttccct tgccagttgt atacgggctg cagcttttgc
    64201 acttcttgga ttgtttgaag cagcatattt gcagtaccag atggtgcatc ttttttacga
    64261 ctatgatgtt tttcaatcag ttcgatctgc cagccttgca acattgcagc tgcttgcttg
    64321 attagttgat tcatcaccat gatgccgaac gaaaaattag cactatacat cacaggtaca
    64381 tgtttggcat gttcttttat ttcttggaac tgtgattgtg tataacctgt cgtgccaatg
    64441 actaacggaa gttgatatga taagctatac gaaaggattt tctctaaatt atctggatga
    64501 gaaaaatcaa taagcagttc tggcagttcc gtaaaagcaa gcgtagttgc ttctttaggt
    64561 gccgtccgta aaagaaggac cgtatctcct ctttcttgtg caacttcttc gactctattt
    64621 cccatctgtc cactgccaat cagtccgatt ttcatttttc aaccgtcctt tcttttaaca
    64681 aaagctgagc taattgtttc tttttctctt ttgaaagaga aactaaaggc aggcgtagag
    64741 gtccggaagg taagtctaat aatgacatgg ctgctttgac aggaatagga ttggtctcac
    64801 tgaacaaggc atggatcagt tcaagtgcat ttaattgctt ttcttttgct tgctgccatc
    64861 ttccgtcctg cgtatctttt actaattcat ggactatttt aggttggata ttcgcccata
    64921 cacttattac accgcttcct cctacactca ttactggtag gatcaaatca tcatttccac
    64981 tgtaaaggaa gaattcttct ccaatcaacc gagcggcatc catcacataa gccatatctc
    65041 ctgaggcttc tttcaaacca atgatattag gatgttctgc taaatttact aatacatgga
    65101 ttggaatcga catgcctgtt ctagaaggaa cattatacaa aataagcgga atcggtgagg
    65161 cttctgcaat tgctgtaaaa tgagcagcta gtcctgcatc acttgttttg ttgtagtaag
    65221 gggtgatgac caaaagtgcg tctgccccca aagaagcaaa atgcttcgct ttttcaatcg
    65281 tttctttcgt attattcgtt ccagctcctg caatcaccgg cacacggcca gccactttct
    65341 ttactgtcag ttgaaggatc tgctcctcct cagattgtgt gagcgtagaa gattctcctg
    65401 ttgtacctaa aactaataat ccatctgttt gttcatctaa atggaattgg atcaattttt
    65461 ccaaaccagc ataatctact gatccctctt cattcatcgg cgtgatcagc gccacgatcg
    65521 aaccttttat catcttcatt cctccaatat tcttgtccat tcatgaactg ctgggccagc
    65581 catttgtatc gcatcctcac cagagatcat caagtctcct tgttccaagt gaacaactac
    65641 ctgatctgct gaaattttcc cagtttcctt agcaaccaca taagaggcac agcaacctgt
    65701 accgcaagca agtgtccaac ctactcctct ttcataggta cggacgatca attcttgttc
    65761 attgactact tctacaaagt tgacattggt tttttctttg aacaaaggat gatgacagat
    65821 cagttcacct ctttttctcc agacttcctc acgcgcattt tcaacaaaaa caacggtatg
    65881 aatcgttcct aaaaataaac tagtgatcgt tactttttca ccattgatct ctatttcctg
    65941 gttttttatt ggataagttt gattagcttt gattttttcc ggagaatcat ctggcactcc
    66001 catatctacg ctgcaataaa aaggtgaggg atccaacacc gtaatttttc ttgtgcctgc
    66061 taatgtctct acgttgaatt cctgttcatt catcatgttc tgatcattta cgtatcgagc
    66121 aaaacagcga atgccatttc cgcacatcgg cgcgcggctg ccatctttgt tgtaatagat
    66181 catttccaac ggatcgattt ttacggcgat caatccgtct atatcatatt tttcttttgt
    66241 gcataaagaa gcggctaatt gactataatc tgtgtcttct gcgtaatcta ataagataaa
    66301 atcatttccg cagccattat atttatgaag gatcatagga aacttccccc cttagtagat
    66361 cagaaaatgc ttgtctgcga acaatcagtc ttgattggcc attattgaca aaaacaactg
    66421 ctggtcgtgt cgctcgattg tagttgctgc tcatcgagta tccataagct cccgtggaat
    66481 aaacagctaa aagatcaccc gattctgctt tcggcaaata agcttcttta attaccacat
    66541 cgcctgattc acacattttt cctgcaatcg tcactttctc tgttttttct tccgacagtt
    66601 ttgctgctaa atcacaatcg tattctgcct gatacagagc tggacggata ttatctgtca
    66661 tcccgccatc tacaaagtaa tattttttat gtggtgtctt tttgatgaaa ccaatcgtgt
    66721 atagtgttgt accagcttct ccaacaatac ttctacccgg ttcgatcagt aattgacgaa
    66781 tggtcagttt tcgtttttcc aaagcttctt ccgtatattc aatcagtttt tttagtgcct
    66841 cttcgactgg gatcggctga tcattttgtg tataacgaat cccaaaccct ccgccaagat
    66901 tcaaggaaag aggttggtca aaatcggtta agtaattcgt caatttgtcg atttcagcta
    66961 accaagcagt aacatcaaaa atttgtgacc cgatatgagc atgaaatcct tctaactcta
    67021 gatagctgct ttcttttatc aactgaaggg cttgttggca ctctttactt tcatagctca
    67081 tgccgaattt tgaatcaata tgcgcagtga cgatatattc atgagtatgt gcttctactc
    67141 cgacattcaa ccgaagcatg atacagattt tttttaaata gcgttggctt aattctgcta
    67201 ataattcaac ttccatcaaa ttatcggcaa caatatgcaa caaatcattt tcaagtgcat
    67261 agatcagttc ctctggcgtc ttgttgttac catggaagta gatagtatct ctaggaaaat
    67321 cagcttgcaa agcggtatag atttccccac cactgacaac atctagcccg aatccatatt
    67381 cacgaactaa atgcagcatc tcaatcgttt ggaatgcttt agaggcgtaa agcacttttg
    67441 tatcaaaacg tttcgataca aagcctcgct tgaatgacag catcgtttgt ctcatctttt
    67501 cttcatcata cacatacaga ggtgtcttat acttttctgc caatgtgctt gctgtgactc
    67561 cgccaattat caattctgtc attttttcat tcctcttttc actttttttc cgtttttatt
    67621 ggaatttcat ttgataaaga tttgaatttt attggaataa tattaaacaa aattttctga
    67681 attgtctagt atatttcgaa atattttttt aaaaataaga ataaaaatgg ttataaaaac
    67741 a
//
LOCUS       DAZKCW010000009        63200 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000009 DAZKCW010000000
VERSION     DAZKCW010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.009"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(67..1545)
                     /locus_tag="ACG84Z_000643"
     CDS             complement(67..1545)
                     /locus_tag="ACG84Z_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9161510.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(1843..2778)
                     /gene="murB"
                     /locus_tag="ACG84Z_000644"
     CDS             complement(1843..2778)
                     /gene="murB"
                     /locus_tag="ACG84Z_000644"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFP9161511.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2851..3771)
                     /locus_tag="ACG84Z_000645"
     CDS             complement(2851..3771)
                     /locus_tag="ACG84Z_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9161512.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3884..4636
                     /locus_tag="ACG84Z_000646"
     CDS             3884..4636
                     /locus_tag="ACG84Z_000646"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFP9161513.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5500..6033
                     /locus_tag="ACG84Z_000647"
     CDS             5500..6033
                     /locus_tag="ACG84Z_000647"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFP9161514.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6523..7047)
                     /locus_tag="ACG84Z_000648"
     CDS             complement(6523..7047)
                     /locus_tag="ACG84Z_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFP9161515.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(7040..7513)
                     /gene="tsaE"
                     /locus_tag="ACG84Z_000649"
     CDS             complement(7040..7513)
                     /gene="tsaE"
                     /locus_tag="ACG84Z_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFP9161516.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7636..8616)
                     /gene="pta"
                     /locus_tag="ACG84Z_000650"
     CDS             complement(7636..8616)
                     /gene="pta"
                     /locus_tag="ACG84Z_000650"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFP9161517.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8769..9449)
                     /locus_tag="ACG84Z_000651"
     CDS             complement(8769..9449)
                     /locus_tag="ACG84Z_000651"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFP9161518.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9575..10444
                     /locus_tag="ACG84Z_000652"
     CDS             9575..10444
                     /locus_tag="ACG84Z_000652"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9161519.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10470..10985
                     /locus_tag="ACG84Z_000653"
     CDS             10470..10985
                     /locus_tag="ACG84Z_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFP9161520.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(11032..11595)
                     /locus_tag="ACG84Z_000654"
     CDS             complement(11032..11595)
                     /locus_tag="ACG84Z_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9161521.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11650..11829)
                     /locus_tag="ACG84Z_000655"
     CDS             complement(11650..11829)
                     /locus_tag="ACG84Z_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161522.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11906..12415)
                     /locus_tag="ACG84Z_000656"
     CDS             complement(11906..12415)
                     /locus_tag="ACG84Z_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161523.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12511..12891)
                     /locus_tag="ACG84Z_000657"
     CDS             complement(12511..12891)
                     /locus_tag="ACG84Z_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9161524.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            13221..13970
                     /gene="pnuC"
                     /locus_tag="ACG84Z_000658"
     CDS             13221..13970
                     /gene="pnuC"
                     /locus_tag="ACG84Z_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFP9161525.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(14154..15431)
                     /locus_tag="ACG84Z_000659"
     CDS             complement(14154..15431)
                     /locus_tag="ACG84Z_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161526.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15510..16154)
                     /gene="pcp"
                     /locus_tag="ACG84Z_000660"
     CDS             complement(15510..16154)
                     /gene="pcp"
                     /locus_tag="ACG84Z_000660"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFP9161527.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16353..17297)
                     /locus_tag="ACG84Z_000661"
     CDS             complement(16353..17297)
                     /locus_tag="ACG84Z_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFP9161528.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17299..17985)
                     /locus_tag="ACG84Z_000662"
     CDS             complement(17299..17985)
                     /locus_tag="ACG84Z_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFP9161529.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18459..18779
                     /locus_tag="ACG84Z_000663"
     CDS             18459..18779
                     /locus_tag="ACG84Z_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFP9161530.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            18933..19838
                     /locus_tag="ACG84Z_000664"
     CDS             18933..19838
                     /locus_tag="ACG84Z_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161531.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19835..20608
                     /locus_tag="ACG84Z_000665"
     CDS             19835..20608
                     /locus_tag="ACG84Z_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFP9161532.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20789..22213)
                     /locus_tag="ACG84Z_000666"
     CDS             complement(20789..22213)
                     /locus_tag="ACG84Z_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFP9161533.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22424..22870
                     /gene="nrdI"
                     /locus_tag="ACG84Z_000667"
     CDS             22424..22870
                     /gene="nrdI"
                     /locus_tag="ACG84Z_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFP9161534.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(22935..24917)
                     /locus_tag="ACG84Z_000668"
     CDS             complement(22935..24917)
                     /locus_tag="ACG84Z_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFP9161535.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(24931..25827)
                     /gene="murQ"
                     /locus_tag="ACG84Z_000669"
     CDS             complement(24931..25827)
                     /gene="murQ"
                     /locus_tag="ACG84Z_000669"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFP9161536.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(25830..26891)
                     /locus_tag="ACG84Z_000670"
     CDS             complement(25830..26891)
                     /locus_tag="ACG84Z_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFP9161537.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(27102..27629)
                     /locus_tag="ACG84Z_000671"
     CDS             complement(27102..27629)
                     /locus_tag="ACG84Z_000671"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFP9161538.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(27696..29198)
                     /gene="eat(A)"
                     /locus_tag="ACG84Z_000672"
     CDS             complement(27696..29198)
                     /gene="eat(A)"
                     /locus_tag="ACG84Z_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFP9161539.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(29456..30576)
                     /locus_tag="ACG84Z_000673"
                     /pseudo
     CDS             complement(29456..30576)
                     /locus_tag="ACG84Z_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            30702..31643
                     /locus_tag="ACG84Z_000674"
     CDS             30702..31643
                     /locus_tag="ACG84Z_000674"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFP9161540.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(31793..32689)
                     /locus_tag="ACG84Z_000675"
     CDS             complement(31793..32689)
                     /locus_tag="ACG84Z_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFP9161541.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            32958..34298
                     /locus_tag="ACG84Z_000676"
     CDS             32958..34298
                     /locus_tag="ACG84Z_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9161542.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            34516..34959
                     /locus_tag="ACG84Z_000677"
     CDS             34516..34959
                     /locus_tag="ACG84Z_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFP9161543.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(35463..36881)
                     /gene="nhaC"
                     /locus_tag="ACG84Z_000678"
     CDS             complement(35463..36881)
                     /gene="nhaC"
                     /locus_tag="ACG84Z_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFP9161544.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(37284..38507)
                     /locus_tag="ACG84Z_000679"
     CDS             complement(37284..38507)
                     /locus_tag="ACG84Z_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFP9161545.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(38538..39377)
                     /locus_tag="ACG84Z_000680"
     CDS             complement(38538..39377)
                     /locus_tag="ACG84Z_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFP9161546.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(39394..40074)
                     /locus_tag="ACG84Z_000681"
     CDS             complement(39394..40074)
                     /locus_tag="ACG84Z_000681"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFP9161547.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(40076..41149)
                     /locus_tag="ACG84Z_000682"
     CDS             complement(40076..41149)
                     /locus_tag="ACG84Z_000682"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFP9161548.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(41205..41443)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(41486..41719)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(41796..42467)
                     /locus_tag="ACG84Z_000683"
     CDS             complement(41796..42467)
                     /locus_tag="ACG84Z_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9161549.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(42554..45202)
                     /gene="mgtA"
                     /locus_tag="ACG84Z_000684"
     CDS             complement(42554..45202)
                     /gene="mgtA"
                     /locus_tag="ACG84Z_000684"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFP9161550.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(45544..45718)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            45891..46328
                     /gene="ndk"
                     /locus_tag="ACG84Z_000685"
     CDS             45891..46328
                     /gene="ndk"
                     /locus_tag="ACG84Z_000685"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFP9161551.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(46350..47216)
                     /locus_tag="ACG84Z_000686"
     CDS             complement(46350..47216)
                     /locus_tag="ACG84Z_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFP9161552.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(47376..49469)
                     /locus_tag="ACG84Z_000687"
     CDS             complement(47376..49469)
                     /locus_tag="ACG84Z_000687"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFP9161553.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(50218..50841)
                     /locus_tag="ACG84Z_000688"
     CDS             complement(50218..50841)
                     /locus_tag="ACG84Z_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161554.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHVGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(51000..52397)
                     /locus_tag="ACG84Z_000689"
     CDS             complement(51000..52397)
                     /locus_tag="ACG84Z_000689"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9161555.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(52429..53400)
                     /locus_tag="ACG84Z_000690"
     CDS             complement(52429..53400)
                     /locus_tag="ACG84Z_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9161556.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            53774..54199
                     /locus_tag="ACG84Z_000691"
     CDS             53774..54199
                     /locus_tag="ACG84Z_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161557.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(54687..55388)
                     /locus_tag="ACG84Z_000692"
     CDS             complement(54687..55388)
                     /locus_tag="ACG84Z_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFP9161558.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(55404..55844)
                     /locus_tag="ACG84Z_000693"
     CDS             complement(55404..55844)
                     /locus_tag="ACG84Z_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFP9161559.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(55844..56419)
                     /locus_tag="ACG84Z_000694"
     CDS             complement(55844..56419)
                     /locus_tag="ACG84Z_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFP9161560.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            56660..56869
                     /locus_tag="ACG84Z_000695"
     CDS             56660..56869
                     /locus_tag="ACG84Z_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFP9161561.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(57267..57779)
                     /locus_tag="ACG84Z_000696"
                     /pseudo
     CDS             complement(57267..57779)
                     /locus_tag="ACG84Z_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(57905..58606)
                     /locus_tag="ACG84Z_000697"
     CDS             complement(57905..58606)
                     /locus_tag="ACG84Z_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9161562.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(58714..60157)
                     /locus_tag="ACG84Z_000698"
                     /pseudo
     CDS             complement(58714..60157)
                     /locus_tag="ACG84Z_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            complement(60171..62036)
                     /locus_tag="ACG84Z_000699"
     CDS             complement(60171..62036)
                     /locus_tag="ACG84Z_000699"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFP9161563.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(62157..63008)
                     /gene="licT"
                     /locus_tag="ACG84Z_000700"
     CDS             complement(62157..63008)
                     /gene="licT"
                     /locus_tag="ACG84Z_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFP9161564.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
BASE COUNT        18304 a        13194 c        10927 g        20775 t
ORIGIN      
        1 ccttttcttt gaaaaaaaca taaatcagct aataaatatg tgagacaaag ctgccatcca
       61 taaatactag ctgatttttt cagttaaatg tctatttttt tctctgatga tggtatttcc
      121 aaaatattcc cagtcatctg gagtcggtgg atttttccaa attatctgtt ctttattaaa
      181 tttttcaagt aaacaatcag ataaataaat attcgtacga gaagtgattc gactctcaat
      241 cacaatattg taatttttaa atcctttcac ttgagaaata atgtaatcgg tataagcaga
      301 tccttgcgaa aaatcaatac agacatgaat cggtgcttca aaatatgata ccggacaaat
      361 accgaccaat aaaaagagat aatcataaaa taagcgaatc atgaaacgtt catcttttcc
      421 caagaaatag cgtttattct cttgtatgac cttttggatt gctgtactga atattggata
      481 cgtctcgaag aaaaactgta gctgcttttt agacgtaaag ctagtcatct caaagtcgaa
      541 tatccaattt tttcgattga catgcatcat acccatacga agttcttttc gtatatatag
      601 tctttcttct tcagagattt caatcgaaaa tggtaattga tcaatcaatt ccactgacat
      661 tttttgacta atcatgtgga tatcatgaaa atgagcttcc gcaagtccaa atgcgccatc
      721 taattcaaat tcttcttccg tgatcaaaaa caacatgata taagaaatct catcaatgat
      781 ctgctcttta gggatatgaa gaaaagaaat atgtgataaa tccttgatga tcttcattcc
      841 ttctgagctc ttaaagtatt catctgaaaa gaaacgtttt ccgattggtt gattcccata
      901 ggccctcaac aaactaatag tggttagcaa attgaatttg attcgttttg ttgcagacag
      961 ttttaaattg aacagatatt caaaatattg cacgatactc tttgcttcat tcatgacgct
     1021 ttctctaaat ggcatagaaa aaccattaaa gaccccgaaa tataccccaa ataatacgtt
     1081 ccgtatgttt atttcttccc caactaatat gtttttcttt aactttattt gatgctgttc
     1141 aagaaaagag actaattctc ttctttttac ataggctctt gatatgctta aaaaatgatt
     1201 ctctgcaaat ttttcgatcg ttacttttga atccacgatc tccgttaaca gtcgagcaat
     1261 ttttgatcgt tgaaagtaga ttcttcttaa atttttgata tccgtcaaat tcagacgttc
     1321 gacatggatc tctgcttctt ctgaaatttg gatctctggc tttgttttga attcagtaaa
     1381 ttctttattt aattctatga tataatttct tgttttaaat ttagacaaac ctaatgtttc
     1441 atataactta ggcagcacta cataattctt tttctcaaat tctaaatatc tagctagcag
     1501 cagtttttct ctatcttcct cttctataag gtaatccaac ttcatatcct acacctcaaa
     1561 aaatgcctca taccaattac ttgatatgca gatgaaagtt catcttttca cctatactga
     1621 ttttatgatg gattatgctt gttttttcat cagttattct cattttttat cttttttttg
     1681 agaatattgc aaaaaatgga aaaatttatg aggaaatatt ctatattttt tgttttattg
     1741 tgttaaaatg tacaagattt gcgccatttg cgtaaacaac cacaaaaaag agcaggacgg
     1801 ccaccgtcct gctcttttac ttattttaag ttccattact tattaattgg ctaaacttct
     1861 gcttgtttct gatattgctt gtttttctcc aatgatccgc acttctgttt ctaaagacac
     1921 atcaaatttt tctttgatta cttcttggat gtgcgcaatc aattcaatat aatctgtcgc
     1981 tgtcgcatga tcgatattga cgatgaatcc agcatgtttt tcagagactt gtgcaccgcc
     2041 ccatttcagg ccttgcaatc ctgcttgttg gatcagctga cctgtatagt gtcctactgg
     2101 gcgcttaaag acacttccgc atgaagggta ttctaatggc tgttttgatt gacgcaattc
     2161 ggtcaactca tccattcttg ctttgattgc ttcataatcc cctgtttgca aactgaatcg
     2221 agcttccaat acgatagcac gtaattcttg gactttactg tgacgataag aaaataccat
     2281 ttcgtctttt gtcaaagttt tcaatgttcc atcttcaagc aaaagatcca cttcagcaaa
     2341 aacatctttg atctctccgc catacgcacc tgcattcata taaaccgctc caccgacact
     2401 tcccgggatg ccgcaagcaa attcaaatcc agtcaatgat tctgccaaag ctgcataagt
     2461 cgtatcaatc agtgaggcac ctgcttccgc aatgaccatc gttcctttga catgaatctg
     2521 tttcatttca gtcagcatga tgactacacc gcgaatcccg ccatcttgaa cgatcagatt
     2581 gcttgcattt cctaatacca tccaaggtat atcatggatt cggcaataat cgatgatttg
     2641 ctttacttct tcttgttttt tcgggaatgc aaggacatca gctggtccac ctgttttcgt
     2701 aaacgtatag ttcatcaatg gttcatcaaa caatatagta atcgtggcta agctttcaac
     2761 tatttcttct ttattcactg aggattttcc tttcttttct caaacgtcct cattattcta
     2821 tcacgcttaa tacaatcttg ccagtcttgt tcaaagttga tgacggtagt gatctttaag
     2881 cacttcctca cataattcat gacttcttac aacttctttt tgtttaagca attctgtttc
     2941 cgatttacct aaacggatct gagaaaagaa ggcctctacc attggctcaa acccgcgttt
     3001 gactagcgtg tttgtccagt cgccaaattc tttcactttt tttccatcag catcttgaat
     3061 gacaagctgg gtcagatcgt ttacttcata agtaccattt ttacttgtta cttgatattt
     3121 ttctatatta gcgccacttg ctaaatccat cgttaaaata gccgtttgat tttgtgtttc
     3181 taattgtaaa atggcatatt ccaaaaattc ctttgtttct cttatctggt attttgttct
     3241 caaaatgggt tcatctaata aatacacagc tgtatcaata agatgtaaaa acaaatcata
     3301 aaggacgaac tctgtcgttt cttttgccgc tattcgattt ttttgcaggt ggatcaaccg
     3361 cttatctggg atacgtttca attcttctac cataggagca aagcgccggt tgaaaccgat
     3421 catcaaaatt atttggttct tatcagctaa ttcttgcaat tcacgaactt catttagatg
     3481 gacactcagt ggtttgtcaa tataaacatg gataccattt tctagacatt ttttggctaa
     3541 ttcataatgt acttttgttg ctgcgtggat catacatgct tcgatttttt cttctaaaag
     3601 ctcatcgatc gtttcatata gatgttggaa cccgtactct ttttgaattc tttcttttgt
     3661 ttctttattt cttgttgcaa aataaaaatc aagtgttcct tgttttttcg cataagttgg
     3721 taaatatgct ttttctgcga tattccctac accgattaca ccaatcttca tctactttcc
     3781 tcctggatca tttagttact ttcatcttac accatttttt actaaaatga ggtacaatag
     3841 tatcgcaaag gtaaggaaat taattcgaag gagtgtgctt ttattgaaat ttatctcttg
     3901 gaacgtaaac gggcttcgtg ccatcgtaaa taaaaatttt ttagaagttt ttcatgagtt
     3961 agacgccgat tttttctgtc tgcaggaaac gaaactccaa gcaggacaaa ttgatttaga
     4021 tcttccaggt tattatcaat attggaatta cgcggaacga aaaggctatt ccggcacagc
     4081 gatttttgct aaaaaaccag cattgaatgc cacttacgga atgggtatcg atatccatga
     4141 tacagaaggc cgtctgatta ctttggaata ttccgatttc tttcttgtaa cctgttacac
     4201 gccaaattct caaagcgaat taaaacgttt agattaccga ttagaatggg aagaagcctt
     4261 ttataattat ttggaaaatc taaaaaaaca aaaaccagtc atcgtgtgtg gggatctaaa
     4321 tgtcgctcat caaaagattg atttgaaaaa ctggaaaacg aatcaaaaaa atgctggatt
     4381 cactccagaa gaaagagcgg ctctttctcg actgttggat aacgggttta tcgatacatt
     4441 ccgttatttt tatccaaccc aggaaggtgt ctactcttgg tggaactacc gattcaattc
     4501 aaggaaaaac aatgctggtt ggcggatcga ttactttttg acgagcaaag atttagagcc
     4561 aggactagct gatgcaaaga tccatacgga cattatgggc agtgatcatt gtccagtaga
     4621 attagatttg aaataaagag gttgtgaaaa agtcgtttag tttcgagtat taagaaaaat
     4681 tttgtgaaaa tggctttcca cattttgcat aaatttggca taataccgag aaactggctt
     4741 ttgaacactg tttatcgaga gattgtgaaa aagctgtcct gcatcaagta ataagaacag
     4801 ccaaacaaaa atagttcctc atatttttcg tttggttggg cttattaccg cagatacaag
     4861 cttttgaaca ccgtttatta agaggttgtg aaaaagctgc actgcatcaa gtaataagaa
     4921 cagccaaaca aaaatagttc ctcatatttt tcgtttggtt gggcttatta ccgcagatgc
     4981 aagcttttga acaccgttta ttaagaggtt gtgaaaaagc tgcactgcat caagtaataa
     5041 gaacagccaa acaaaaatag ttcctcatat ttttcgtttg gttggactta ttaccgcaga
     5101 tgcaagcttt tgaacaccgt ttattgagaa gttgtgaaat cagcgtcctg acctgagtat
     5161 tagagaaaca aatggcaaaa tagttcctca tattttgcta ttttttgagc taataccgag
     5221 ggtcagctga ttgaacaccg tttagtggag aagttgtgaa aaagtcgcct actttcgagt
     5281 cgtaagaaat ttttttgaaa atggttcctc acaactttgc ataaatttga cttaataccg
     5341 agaagtcatg atccccatct aactccaaat cacaaggaat gagttcaaaa actagctttt
     5401 ctcaacaaat attacataaa aaattctatg ttttttgtta aatttatttg cttttttcaa
     5461 aagtatgtta cagtaatttc ccaaggaggt tttacagaaa tgaattttgt tgccatggat
     5521 tttgaaactg ccaatcatca gccttatagt gcttgttctc ttgcgctagt catggtaaaa
     5581 aatagccaga tcgttgatga attctataca ttgatacagc ctgagactcc ttttttctgg
     5641 cgaaatgtcc aaattcacgg aatccatcaa gaagacgtac gcaatgcgcc gaaattccca
     5701 gaagtctggc aaactatcca accatatttt caaaaaaatc gtttagtcgt tgcacataat
     5761 gctgcttttg atacaaaggt cttagcggga tgcttagatt attatcatct tgaacagcct
     5821 aattatcttt ctttatgtac agtgaaaagt agccgtcgcc tgtttcctga atttccaaat
     5881 catcgattga acactgtgtg cgaaaatttg aacatccaat tagatcatca ccatgatgca
     5941 ttggaagata gtcgtgcatg tgcggaaatc ctgctttatc aagaaaaaaa attcgggaca
     6001 gatccattga aaaaacttgt gactataaag taaaagaata cttatgaaac acacaaagag
     6061 gtcgtgagcc tgccgtttca ctccgagtca caaggagcaa tttcaaaaaa tagcttctca
     6121 tgtttattaa atattgtgac tggtgaccga ggagctggca ggagaacacc gtttattgga
     6181 gaggttgtga aaaagctgtt ctgcatcaag taataagaac agccaaacaa aaatagcttc
     6241 tcatattttt catttggttg gacttattac cgcagatgca agcttttgga caccgtttac
     6301 caagaggttg tgaaatcagc gttttgacct gagtattaga gaaacaaacg gcaaaatagt
     6361 tcctcatatt ttgccgtttt ttgagctaat accgaaggtc agctgattga acaccgttta
     6421 ttcaaaaaaa atggactgcg acacgacttt tgtcacagtc ccttcgtgtg tttttctgcc
     6481 ttctcaaaag gatgacagtt tctcactctt ttcctatttc ttctattcaa tcaaataact
     6541 cattttatat acatctaaaa attcacctag atctgttctt gcccctctag gcatgaccgc
     6601 ttcgatttgg aagcccattt ttcggtaaag gtgtacggct ctttcattac gaacttgaac
     6661 gtcaagctcc aatcgaaaaa gtacacccat ttccttcgcc caactgatga tttcttctag
     6721 cataagagtg cctagtccca ttccccaata ttcctgcaga atactgatac cgacttctcc
     6781 cacgtgagac aaacgaaatt gactgtctgc cttgacagat gctgttccaa taatcgtccc
     6841 ttcatagatt gcaagcagca ataaattatt attgctttcg tatatataat ccaactcttc
     6901 ttctaaggtt tctggtggta acaggagttc tgcttcatcc aaaactaaaa attctgtctc
     6961 cttattaact tgtcccatca tcaaaagaat gtcttttgca tctcctggca ctgcttcccg
     7021 caagatgatc ccaacttctt cactcatgat tttcagccca tttttctaga attcgctgtt
     7081 tgaaggtttc actttgctcc ccgtatgaga ttagtttcac ataccgcttt tctaaatctg
     7141 tatcactttt ttctaaaatc agttccaaat aatcctccgg cagtgcttct tctaatagat
     7201 ttccccattc aacaacggaa agcccatcac cttcaaaata ttcatctaac cctaaatctg
     7261 ctccgctagc tgctacccga taaatatcca tatgatacaa cggaatccga ccttgactat
     7321 attctctaat aatcgtgtat gtcggacttt tgatcatttg cgttatccct aatccttggg
     7381 caattccttt cgtcaacgtt gttttacccg cacctagatc accagtcaat atcagattgt
     7441 cacctggcat tgcggaatga ccaattgcct ctgcgaattg ttctgtcatt gttaatcctg
     7501 atagttcgat catttttcat cttctcccgc tcttctttct ttttgccagt atatcgcgta
     7561 atgaagtttt tttaaagaaa aaatgaacta gtcaagaaca gcagctgctg tttttggcta
     7621 gttcgcgtgt atttgttaat caatcaatgt ttgtgctgct gtgataatcg ataatttata
     7681 tacatcttct tcatttgctc cacgagacaa atcagaaacc ggtttgttca agccttgtag
     7741 aattggtccg attgcttcaa agttaccgaa acgctgagca attttatagc cgatatttcc
     7801 tgactgcaat tctggaaata caaagactgt tgcttgacca gctacttctg aatctggcgc
     7861 tttcagttgt gcaactgaag gaacataaga agcatcaaat tgcaattcgc cgtcgatcat
     7921 gtattgtggc gctagttttt tagcgatttt agttgcttca actactttgt ctacttctgg
     7981 cgatttcgct gagccttttg tcgagaagct catcattgct acttttggtt cgatatcgaa
     8041 caattctgct gtttttgcag aatctacggc gatttcagcc aattcttgcg cagttggatt
     8101 cacgttgatc gcacaatccg aaaagacata tttttcttga tctcttccac gtaccatgat
     8161 catcgctccg cttgtccgac tgatgccagg ctttgttttg atgatctgaa gtgctgggcg
     8221 aacagtgtcg ccagtcgaat ggatcgctcc agagaccatt ccgtctgcaa tccccatata
     8281 cgtaagcatc gtaccaaagt aattcacatc ttttaaaatc ttttctgctt gttctttgga
     8341 tgcctttcca tttctacgtt caacaaaagt atccaccatt tcatcccact tatcgtaatt
     8401 atcagggctg atgatcgtaa agctagatgt tttgattcct ctggcatgcg ctgcatttct
     8461 tatttcttct tcgttcccta ctaaaatggg ttccacaagt tcttctgctt tcaaccgggc
     8521 agctgcgcct aaaatacgag catcagtagc ttccgggaaa acgattttga tcccacggcg
     8581 aacaatttta aatcttaaac tatcaaacaa ttccacaaga tgacctccag acgtttttat
     8641 atgtattatc atacactatt ccagaaaaaa agaacagttt attttatctg tatcagtcaa
     8701 aaatgctgga aaaattaagt ttttcacata caaagcgaac tgcactataa caggaaagcg
     8761 ctgttttatt acactgtttc aggcagttgc caatcaatcg gttcttctcc taacgcaagg
     8821 agcgcatcat tcgttttcga gaagggtttg gaaccaaaaa agccacgact tgcagataac
     8881 ggactgggat gtggagatgt tatgatgata tggcgactct tatcgatcat tttgattttt
     8941 tcttgtgccg gttttcccca caagataaac acgattggtt tttcccgttc atttaatttt
     9001 tcaatgatcg tgtctgttaa tctttcccaa cctttcccgc gatgagaata cgcttgccct
     9061 tcccgaacgg taagaacggt gttgagtaaa aggactccct gtttagccca tgacactaga
     9121 tttccatgtt gaacaggtgc gattccaaga tcatcataaa gctctttata gatatttctt
     9181 aacgatggcg ggatctttac gccaggttgc acagaaaaag ataagccatg agcttgattt
     9241 tctccatgat aaggatcttg tcctaaaatc accactttaa cttcttcata aggagtcaat
     9301 tccaatgctt catagatatg atacatatct ggatggatct tttgggacgc atattctttt
     9361 tttaaaaatt ctcttagatg cagataataa tcttttgaaa attctgagga caaaacttct
     9421 tgccaactgt tatgaatgat ttctttcaaa aactccacct cctaataaaa agaataactc
     9481 acattttctt caatcacaag ggacaatctt caccctcagc acttgattaa tatggtaaac
     9541 taggaacaag aagcagaaag gaacgataat cattatgatc aaattaattg catcagatat
     9601 ggacggcaca ttattagatg cccatatgag tgtttctcct gaaaatgccg aggcgatacg
     9661 ttttgcaaat gatgccggtg ttgagttcat ggtcgctact ggtcgaaact atcaagaagc
     9721 tcgcgcagct ttagatgagg taggaatcga ttgtgcgatg atcactttga acggggcaca
     9781 ggtatttgat aaagaaggaa attcattgtt taccgtgtcg attccaaata atcaagcaat
     9841 ctctgtttta gatattctag atgctaacgg tatttactat gaagtagcaa ccaacgatgg
     9901 tctttattct gaaaatcaag cgaaacgaat tgaaagtttt gcttccatgg tggctaccca
     9961 tttacctcac cttacgtata aaatggcgat tgccatggcc tcagctaagc tggagttatt
    10021 gcacatcaca tacgtggaca gtattcgtgc tattttggaa gaaaagaatc tggaagtttt
    10081 aaaaattatt tgttttcata cagaagggcc agctgtatta ggtccagttg gaaagcagat
    10141 ttctctttta ggcgatctag ccgttacttc ctctggtcaa aacaatatcg aagtgaacca
    10201 taaaaacgct caaaaaggaa ttgctgttgc ccatgtcgct cacgagcgtg ggatttcttt
    10261 agaagaagtc atgacgattg gcgataactt caatgatgtc agcatgctgc aagtagcagg
    10321 agtcagtttc gcaatgggaa atgcagaaat cgaagtaaaa gattatgcca aatatacaac
    10381 ggacacaaac cttgaatctg gcgtaggaaa agccatattg cgcgcgattg cagaagactt
    10441 gtagttttat ctagaaaaga gggatataga tgtcagaatt tttcattcag gaaaagcagc
    10501 ttggacgtgc aactcggaca attgtcaaaa acgaaaaagg acattccctg tttttgatgg
    10561 ttggtcgctg gggaacaaag ggcgatgcat tgtctcttta tgccatgaat ggcgatctcg
    10621 ttgctcacat caagcagata agcctgacat tcggtacgcg ttttgagctg tataaagagt
    10681 tcgaaaaggt gggaaccatg cagaaaatat tcaattggcc cggtgacttt tattatattc
    10741 gtagacttca ctggacagtc caaggtgata tctataatca tcaatatcaa atccatcatt
    10801 tcaatcagca aatcatgaaa atggataaag caacactttt ttcaggagat tactatgtat
    10861 tggatgtctc aaatgatgaa gatgctccag tttgtatttg tattgctgcg gttttagatt
    10921 actggctcta ccgtaaagac aaaagtcgcg ataagcctgt ttcttaccga cttaacttaa
    10981 gttaaaaaga tgtacctgaa atgcggaaat acgcatttca ggtacatctt tttagatatt
    11041 cttttgcata tgatcataaa gatgaccact gatcatccgc tgaccgacaa ctttgaagtc
    11101 atggcgttcg tataattttt tagcctttgg atttttttca tccacactta gaccgatgac
    11161 ggagcgatta gctttcttcg ccaatttagg taatgcttct aataatcgcg aaccgatgcc
    11221 ttgtcctcta aaatcttctg atacactgat agagtccaaa taccattcgt tgggaaacgt
    11281 ttctttatca atgaacaaac gtgtagacgc atctagctga tatttctcta agataggtac
    11341 cagtggctga tcgatgattg attcttcttc atctgtataa ccgtaagcaa ctcctgcaac
    11401 tttaccgtct atttcttcta cgatacctcg tgaataactg taacgataat ttggatcagt
    11461 gattgcttct tctaaaatct ctaaagtctt ttgttcccct gtctgcttca aaaatggcag
    11521 ttccatatct tttagaatca ctaagatcaa tggggcgatt tctggagcat cttcttttct
    11581 cgcaaaacga atcatagttt cctctccttt tctccattct aacatgcaga aaaagaaatc
    11641 gcaaaatcgt tattttaaaa aatcttcaat cttttcagta atgaaataac catgagtaac
    11701 gattcttgcc gcttcagttc ggcaataagg gcagacgact ggcatttctt tatcattatg
    11761 ttcgactaca ttattgactt cttcgtatgc aaattttttt ccgcaattag ggcatttcat
    11821 tttttccatg ttatctcaac ttcctttcat ctttactctc ttagcttact cttatattgt
    11881 aaaaaagaga agcaatatcc ttcttctatg cagatatcca tacctgacgg tcctgttctc
    11941 catctattaa tcggacttta taataaggac gttcatcttt gactagaagt gtccactctt
    12001 tcacttttgc ttttttcccg tagtagctga ctgcttcctt catcgctgct tgcggttgtt
    12061 tgaactcttc cgttttttct atatcaaaaa gatgttctgc ggccttttcc gtgtcatttc
    12121 gtacggttgt tttcccagtg gatggattga ctgctatgac ttgtccttca caaaaaaact
    12181 ggtattcata tgttgcattc gtaggattct ccaaatcttt ttcaactgca aaatgaatag
    12241 cagatatgtt atgttctttt gtttcgtttt ttacgattgc tgctgctttt ttcaatgaga
    12301 tccgatattc ctggtcacta atatcatcca tgtgaaaagc ggcattgagc agtcccgtca
    12361 taccggtaat ccctattacg atgagggcag caacaccaaa catcattttt ttcattcttc
    12421 attctcctgt ttcttttttt taaagaatat caagaaatga acgaatgaaa aatcgaatga
    12481 aacgaaaaaa aagtgacaat tttgttatct ttattcgtgc agttctaatg gcaatccgtc
    12541 tggatcaaag aaaaacgtca ttttttttcc tgtaaaggta tcttctctaa tcggttctga
    12601 ttcgatccct aaggactgca attctgcaat tgtttcttca atatcgtcta ctttgaaagc
    12661 aagatgacgc aagccacaag cttctggata gtttggtcgt tgtggcgcat tagcaattcc
    12721 aaaaatctcc aattcagcac ttcctagttt cagatctaat ttatagtcat ctcgttcttt
    12781 gcggtaattt tctctgatta cttcaaatcc taatttatta acataaaaat cacgtgattt
    12841 ctgataatct gaaacaatga tggctatatg atggatcgtt gtaaggttca tatgagcact
    12901 cctattcttc gtttaagctc ggatctatat taatctccag ttccattgta aatgtgtcag
    12961 attgaaaaaa atagctgttt ttccttttta taagaaaaaa ggcaaaaaaa acagaaagta
    13021 ggtcctccaa gacactcttc ctgttcccaa tataataaat gaaagtaaga aattatattt
    13081 tcaagaaaac aaacagaaaa ttatcataac acaaattatt tataattgaa agactagttt
    13141 tttttcaaga aaagcataca atagattgtg ttagtaaata cagaacacac tacatttagt
    13201 gtcttaagga gtcctcatac atgaagtcat attttcagtt tttagctcat cagctaaaag
    13261 gctggccgca acaaaattat tatcttttct ttttcagtct tggctgccag gtcatgactc
    13321 ttgtcaatag tcccatcact tggctgtccg ttattacatt tatcggtacc acgcttggtg
    13381 tattgtgtat tttatccatc aatgcggcaa aatcagtcaa cggtatttta ggtattttgt
    13441 ctgcgatttg ttttattatc gttgggtttt cagcaaagaa ctatttaagt atcggtgaac
    13501 agattgctta tatgatcaca ttggatatcc ccgtattgtt aagtaaagaa tggaatcata
    13561 atatggcttc aaaaatccga aaattcactg gaaaaagctg gtttatcgca atcatcagta
    13621 ctttccttgt ctatcttgtt tcaggattcc tgattggtcg ttatacagat gatcctcggc
    13681 cgtgggtaga tgccattgct ttttctatta gcttgactgc tggtatcatc agtttcttgc
    13741 gttacaacaa ccaatattac tggtggttag cttcagggct tgctcaaatg gtcctttggt
    13801 atatttcatt tacgcatgga tctgcaagtt tggcgatgtt cgtgaacagc tctgtttact
    13861 tgctgaatga tgtccttgca tttaccgttt caccttggta taaccaaaaa gaacgtgaac
    13921 gtatgcaaaa aatggaagaa gaatactaca acgcacaaca acacgcataa aaaaactgag
    13981 cgtgggacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcggaa
    14041 tcagaagcaa ctccttcgga aataagctga aattcacaaa aatttgaaaa gcaattttcg
    14101 tgaatttctt cttatttctt ggagttaaac gcttctgtcc cagcctctat tttttatagt
    14161 aattccttca gatactttct tgcctcatca ttgaaacgca gtgattcttc taacttctga
    14221 taatattcca acgcttgttt ctgagcttca gtaaaacgat aatgttttcc tttccatttg
    14281 tcgattgtct cttgcacatt tccagattgg atatctttca ctactagttg ccatttttct
    14341 tttgagactg tacggtcttt cttatcagca gattgtatag cttctcgttc tttacgcaat
    14401 acttttaaaa aaccatttct gactatccga ggaatgctgt cgaagaaccc ttctgtaaaa
    14461 ccatagcgac aatattgctt ccaaataaat agatagattt ttggttggat gaatcgttgg
    14521 tttttcgcaa aatattccat ctgagcagtg acttctggtg ttcgttgacg ttttgtcttt
    14581 ctcaacacgg aaataaatgt ttcaaaataa gcattaggat gtactggcac ttcttcatat
    14641 acgatggatt gccaatcttt acgtaaaaat gcgcgatagt tgatcaagaa ttcttctaca
    14701 tcctttacta attcttctgc aaagtcgtca aatagttctt tttttatctg tcgctttttt
    14761 gactgcccat tgatgtgttc acttattttc ttgatttcat tttccaatgc ttgataatcc
    14821 gctatgtaaa tcggcatttc tacttggcga aattctgcga gccgctgagc taattttata
    14881 tccggtaaat atggctgttt catccgacga ttttggtaca agacaaaaca gtatttttgc
    14941 catagtcctt caggaaaatc gatattcttc tgcttaagcc ataataattc gtctaaggcc
    15001 agatcaactt ttgtcattcc ctgatggatc gaagctgcca ctgtcggaga gacatgcagg
    15061 tgatcggcaa agtggttgat gcctagtttt aggatctttc cggtttttgg cgatttaacg
    15121 atgtattgca cttttaattc tctaccacac tcacaataca atttttgctg gcttcgtttt
    15181 gttcgaaaaa acggattgat cttgaagtca gaaaacaccc aatctgttgc agctaaataa
    15241 tgttcttcca taaaacgaga gctgattaga tatcggcggt gcttatcgac tagttcccgc
    15301 tgttttttcg ttaattttgc atagatctcc caacgttgac tgcttgtgta ttgtttagaa
    15361 attttgatgg gatagctttt gctgatttct tttggaaacc attcttcaaa gacggattgc
    15421 cattcttcca cggctgtttc tttcctttct aattacaaaa agctggctac taacataacg
    15481 ttagcaacca gccagtgttt cttgctaaat tagtgagttg ttccggcatt tccggaaata
    15541 tcttctttat tttctactgc tgcttcaact gcataagtca aagaagaagc aatgtcttct
    15601 aaagacatag aaggcgtacc cactggacga tcgatcactt gatcgggtga gaatggcacg
    15661 tggatgaacc cacctcgaat tgccgggaat tgtgtttcga tcaaatgaag caaacgatac
    15721 atgatatcat tgcagacaaa tgttcctgct gtataagaga tgtacgctgg tagaccatga
    15781 tcttgtacat tttttgtcat tgctttgatt ggcaatgagg taaagtaagc ggctggaccg
    15841 ttttcttcta aagccgtatc gaatggctga tttccttcat tatcagggat tcttgcttct
    15901 gctagattga ttgcgacacg ttcgaacgag actgctgacc gcccacctgc ttgtccgaca
    15961 cagatcacga catctggttg gtgctgttgg atggcttctt tgactacttg actgcttttt
    16021 tcgaatacgg tcggtacttc cactttgatg atttcagcac cgctgatttc atctggcatt
    16081 ttttttactg cttcataggc tggattcact ttgtccccac caaatggatc aaaacctgtt
    16141 actagtactt tcatctgttg ttcctccgtc cgattgattt aacatatggt tatcttttat
    16201 cataccattt tccttgaaca gcgtaaataa aggaaacaat agtttaaata acataacaga
    16261 tcaaacttaa tatattctta taaaaaaata gtgttccact acaatgttag aagaggttgc
    16321 gacaattatt ctgtcacaac ccctctcttc tattatttaa atagaatcat ataagcaatt
    16381 tggaaaacta gcataaataa cgcaataaac aactggtttt tgatcactcc gtatttgtct
    16441 ttcatctcca gcatcgctac aggcacgata ttgaagttag cagccatcgg tgtcagcagg
    16501 gtcccacaaa aaccgcaagt caatgcaacc attcctatta acgctggatt cgctccatga
    16561 ctaaatacga atggtgcacc gatcccaacc gtcatcacgg tgatggccgc aaatgcattc
    16621 cccatgatta ccgtaaatat caccatgcca agagcgtaaa tgatgatgcc gatgttcaca
    16681 tttccttctg gaacgatcgt acctactgca ttggaaatca ctgtcccaac tccagcgctt
    16741 gtaaataccg cacctagaga agctaaaagc attggcaaca tgcttaacgg ccctactgtg
    16801 cccagcatat ctgctgcatc atctaaaaat gtacttggtc gattatctcg agaaaagaac
    16861 atcaagatta gcatggctgc aaaaacaccg acgcccacgc cgactaaagc acctaaattg
    16921 gtaaatagag caaacaagat cgcaaagaca ccgatactca aagctggaat aaaaattttc
    16981 attcctagtt tgtctgacat tttttccata tattcttttg atggaagccg gctttctcct
    17041 ttgctgactt tcttagcaat tgctggtatg gtcatcgcaa agatcaagcc accgttcacg
    17101 attgccggaa gccatcttcc tcctgcaata actaccccta agaccgtcca gaaaaaggct
    17161 gacccataac gatgaggatt ggttttatct gttaaatttc ttactccagt gtaaatcaat
    17221 acgagtccca tcacgatata aaggatctcc agtaatttat cgcctaataa aatatcagga
    17281 tttgtaaaaa agtccatctt attgcccctt tcctggataa tatttcttcg ctaatttctt
    17341 ttctttaaga tagaagtaga cacttgccac aactaaagcc gtgatagcca ctggaacttc
    17401 cactaaagca agctgtccca atgttacgtc atatcctaga tctttcagtg ttgattggac
    17461 tagcaacgcc cctgctcctc cgatgaatag tacttggcca aagaaccagc agacattttc
    17521 catagctgaa gccatacctt ttagttcttc ttcatgctta ggatggactt ctaacccttt
    17581 tgattcgatg gtccccaatg ccatcggtaa aatgattgga cgaacaaatc cagcaactcc
    17641 accaaaactc acgttaaaag ccgcaaagat cattcgaaag atcccataaa tatctacaat
    17701 cataccagca gatactttct tgaatcgctt gatcaaggaa gccgctgatt ctttcagacc
    17761 atttctttca agcgttcctg ttgccaacat aatgatgata aaaatcgcca tcccgcgatt
    17821 gtttacaaaa cttgtaccta aaagttctaa cattccttga atgccaagac cgccagtcaa
    17881 agctgtaaca actaaagcaa ccattacgat caatatcgag tctaatttaa atgcaaaccc
    17941 gagaataaca atcaagacgc ctaaaaggct aagataattt tccatatatt ttcctccata
    18001 aaatgacaat atttttttaa ttataaagca aaacacataa aaaatatagt tgttttctca
    18061 cgaaatagac actattttta aatatttttc gttatttttt tatcacaaaa attatcttac
    18121 ttattgtaag gtaaagcttt ttttaattta ttgcccgata atatatagaa ataaggtcta
    18181 gttactgttt tttttaaatg attaataaat aacaacttct ttctatgaaa ttgcaaagca
    18241 ttcatcttct tttccgctaa cgatatatcc gtcagtgctt ggtacacttt actaaaaagt
    18301 atgagattgc cgatatctgg ataggtgtgc tatactacag aaaaagatat acaatctgcc
    18361 accgggtagg ataaagagga tgatcattcc attaggtctt tgaagggatg attttcctct
    18421 ttttgtgtat ttttttatag ttaaggagga atgtaagtat ggcatggatg gaattaatca
    18481 tagcaggaat tttggaagta ttctggtcaa cgatgatgaa atggagtgat ggtttttcta
    18541 aaatcaatta ttctttttac acagtgattg gcatgattgc tagtttttac tttttgtcaa
    18601 aggcaatcaa aagtttgccg atgagtctct cttatcctat ctggacaggg attggcgcag
    18661 ttggttcggt cataattggt gtggtcttgt ttcatgataa gctgaatctt tccacttggt
    18721 tctttgtggg gatgctactc atcagtatca ttggcatcaa gattactagc ggccactaga
    18781 cacttggaat aagtactgat cagaaaaaat aagccttttt atttaatatt caattttttt
    18841 atgaaaaaat aagaaataag tccaatgacc tagcgacttc tccactcatc aggtgtatgc
    18901 ttgtactatc tatagaaaag gagtgaatat ttttgaaaag tctttcggtc caagaattat
    18961 ccaagaactt tggtcacaaa caagccctca gcgatgtcag ttttagctta tcccctggca
    19021 aaatcgttgg attagtaggt cctaatggcg ctggaaaaac aacgatcatg aaagctattt
    19081 taggactgat ccattactca gatggaacaa tctgtattgg tgaaaatgag atttctccct
    19141 ctagtcataa agggttggaa caagtaggag cattgatcga atacccgggt atctatccat
    19201 tcttaacagg ctatgatcat ctgaagttat tctctgaaac caacgatgta tctgctatcg
    19261 acactatcgt gaatcagctc aagatggaaa agtacattca caaaaaagcg aaatcctact
    19321 cgttgggaat gaaacaaaaa ttgggaattg ctcttgcctt actgaaccat ccgtctatcg
    19381 ttattttaga tgagccgatg aacggtttgg atccacaagc aacaagagat gtgcgaaaaa
    19441 tcattaccga cttggctact cagggcacct ctttcttgat ctccagtcac ttactcagcg
    19501 agcttgaaaa aatggtcgat gagctgatcc tgatcaatca aggaaagatc atcaaacaat
    19561 gtacaatggc tgaattgaac caaacagcgc aagatttcat cgttatctct acaacaaatg
    19621 atctagctgc tcgaacgatc ttgacagaag ctggatatac tttggaagat cctgataaaa
    19681 tcaagctttt aaaagaaaac gaagaattat taggaaccgt gatccagcta ttgtctgcac
    19741 aaaatatcca tgtgacagac gtccagcatc tgacgaatga tttggaatct tctctattgg
    19801 aaattctgga ttcagtaaag ggggaagaag aaaaatgaca ttgcttgtaa aacaagaatt
    19861 atttaaattg atcaagaaaa agtcaactgc tgttttatct gttctattag ttgttttgct
    19921 cataggaaca gcacttctag ccaaaaaata cacgacgatc attgatccag ttgaaatgac
    19981 tgctcagctt tttagtgcca catcttggat tgtctttatc atgattgcag ctgcaagcac
    20041 gatcatttcg atggaagcac aatatggtac attgaaaaat ctcctttatc gaaagtattc
    20101 tcgaggagaa atattagtaa gcaaatggat cacattagtt atttattctg tttatttata
    20161 ccttttagct attattgtca ctgtgttgat gaaactgatt cttttccctt cgatttcctt
    20221 cacggagaag gtttctactg gtcaaacact gatccaaagc ttgttcactt atactttggg
    20281 tagttatatc ggtttatggc tgattttaag tttagtgttg atgattgctt gctttatcaa
    20341 tagttccggc gcatccatct cagcaggaat cgtcttttat tttgcttcgt caatcatatc
    20401 tggtatcctt attgcactca tccaaaaatg ggagtggatc aaatggaatc cgatcagtat
    20461 gttgaatctg caaaaccaaa ttggaaacga agagatcatg aagcaattga ctcatctttc
    20521 tactaatcaa atgctattcg gtaatttagc ttacatcgtt ttgttcttag cattaggata
    20581 tctcgtattt aagcgaaaaa atgtatgatg actcatcaaa aaagaggctg tgaaagagac
    20641 gttcagcctt attgccgatt ggctgtctct taaacaccgt ttattctgaa aaaggagctg
    20701 tgacaacatt tgtgtcacag ctcctttcct agtatgtttt tgaataaacg acaggctcac
    20761 aacctctctt tatacttctt ttatacttct atacgtgaag catcccagtg gcaaataaaa
    20821 ccattgcaat cactccgacc atcgtcacac ctataagtaa aatcttatct aagtggatat
    20881 gttgtacagg ctcgttttgc tccttacgtg ctttgaggta aaaataaatg cctggcaaga
    20941 aaagaacaag aacaagcatt acttcattaa aggctacgac tagcatagcc catacttgaa
    21001 aggcacttgc taaaagccct actaaaaatt ggacccattc tttccgctga taagaaagtt
    21061 tcatttggta caatcctaag aaaagccacg tgaagaaaat agctgctgta ccaagtgtgt
    21121 aagcaaagtt ataagcactg tcagtgaata ataatgaaag taaaaagaca ttcgtacata
    21181 acgtcgtcaa tacgatagca taagttggtg ccccattttt gttgagtttt ccccatgctt
    21241 taggcaaaag tccgtcttca gccatgtttc ccattgtttc aatcggtaag atcgtccatg
    21301 agagccaaac accaactaaa gaaatgatca aaccgccgtt gatcacgact gctccccatt
    21361 taccaaccat catttcaaac acatagccca tagcaggctg cgccttgatc gtttgcagct
    21421 gattcatcgt cattgtccca tatggaagca tggaaaccaa gacgtaaata ataatcaagc
    21481 cgaatatccc tagaatcgtt gctttcccaa catctgattg tttttttgct cgtgaaccta
    21541 cgacagaggc tccttcaata ccaacaaata cccaaagcat caccatgatg caactcaata
    21601 cttgactgga aaacgggatc ggctgtccat tcgcattcaa tataatgtcg ctagaaaagt
    21661 tatcaatgaa ttgttggatc gaaaacgtgc tgatagctac tacaataaat aaaaataatg
    21721 gcactaattt acagaatgtg acgatagcat tgacgaaact agcattttcg actccccgat
    21781 tcactagcca tgcatatccc cataaaaaga ctgtactcat cacgatcgat gccagatttt
    21841 gcccaccttc aaatactggg aagaaatatc ctaatgcgct catcaacaat gttgcaaaag
    21901 ctacgttgcc taaccagcat gtgagccagt aaccccaacc gctgataaaa ccagcgaaac
    21961 ggccaaaacc ttcttctgcg taactaaaga tcccgccttt taaatctgga cgttttttat
    22021 tgatattatt gatcgacaag gagagcatca acattgctgt tcctacgagt acccaactga
    22081 aaatagctgg gccgccagcc gatccggaga tgtccgtcat aataccaaat acgccacctc
    22141 caatcgctga accaattact aaggcagcaa gtggaattaa accaattcct tttttctgtt
    22201 gctctgtatc catgtaagca tcctccaaaa taaaaccgct tttatcaaaa agtataacaa
    22261 acctttttta tttttactta attaataaaa actttaatag aaatataatt ctaccggctt
    22321 ttttctcatt atacaagcaa agcgcctagt ccctttccaa attacaccac caaaaaactt
    22381 aaaaaagatg ctatactaaa aggaaagaat tggaggatga tccatgaaca ttttatatat
    22441 atcgatttca ggaaatacgc gtgcctttgc caaacatcta gcagaatatg ctgaaaaaat
    22501 gcatgcagaa gatcctgtca atcctgaagt tactttaaaa gaaatccatg aaaatagtga
    22561 ttttacgaaa gaaacagaac cattttttac tttcgttcct acttatttag acggcggaaa
    22621 tggtttagat aacggtgata cagaaatctt gaccgaaacg atgcgtgaat atctggaaca
    22681 tgaagacaat cataaacttt gtcttggtgt agtcggtagc ggaaataaaa acttcaataa
    22741 tcagtattgt ctaacagcca aacaatatgc acaaacattt ggctttcctt tcttggcaga
    22801 ttatgaatta cggggaacac catctgatgt gacacgaatt tatcagattt tagcagaaaa
    22861 caataaataa taaaaaagaa gaagctgaaa aatagatttc agtttcttct ttcgtttcta
    22921 ttgtttctat catattaagc tttgacatcc atcacaggtg cttttgcttt tgctttacct
    22981 gttttttcca agacaaagtt ttttacacga tccatattgg ttaccaagac gatcatggat
    23041 gtttctttgc ctgctgcttt gatcgcttct aagtcagctt ctgctacaag cgtatcaggt
    23101 gtcacttgct gcccttctgt tactttcaca tcaaatggcg taccgcctaa gtcaactgtg
    23161 ttgattccca tatgaagcaa gatttctaaa ccatttggcg ttgtgatccc aatagcgtgt
    23221 ttcgttggga agacagagct gactacccca gtaactggag aatagatatg tccgttttct
    23281 ggttctacaa agtagccttc acccatcatc ttttgtgcaa aaactggatc acttgcttta
    23341 tctaaagaaa caactgttcc gtcagcaact gatgagagga tagtcacact ttcagctgaa
    23401 gtttgaggta ctactttttc aggcacttca tttactgtgg ctgtttcagt cgctaattct
    23461 tctttttcta aacggtcttt aggaataccg aagaagaatg tagcaacgaa gccaccagca
    23521 taagctgcca ataatccaag gatgtagcct aaccatttac cgtcagagat caatgggatc
    23581 aaagcggctc ctgaaggtcc aatagcgata gccccgacat ttccgatcat tccgatcact
    23641 gccccgccga tacctccacc gatacaagca gtaataaatg ggcgtcctag aggtaatgtt
    23701 actccgtaaa tcaatggttc gccgattcct aggatcccga ctggtaaagc tcctttgatc
    23761 atttctgtta attctttatc ttttttgcag cgaatccata atgccaatgc tgcacccact
    23821 tgtcctgcac cagccatcgc aagaattgga agcaatagcg tacgaccagt ttcatcaatc
    23881 atttgcacat ggattggagt caaaatttga tgcagtccga acataaccat cggcaagaat
    23941 aatgtgccta gaacgaagcc ggcaaatgct ccaccaacgc caagtaccca gttgatccca
    24001 ccgaccatgc catcagaaat gaaacctgct aaaggcatga tgaagaaaat ttcaatcaga
    24061 ccgatggcaa tcaatgaaag agttggtgta acgatgatat ctaccgcatc aggtactact
    24121 ttatgcagtt ttttctcaac gattgacaat agccaaacag cgaagatgac acctaggatc
    24181 ccaccttgtc cagctgcaag agcttcacca gtaaataagt ttttcagtgg tgcttccgga
    24241 ttcatccctg tcagcatcac aacggccccg ataactccac caagagttgg tgttgcacca
    24301 aaaacttgtg cagcattgat acctgtatag ataactaggt agctaaacat cccgtttttc
    24361 aagatgttca tcacatcgat atattgttgc catgttgctg catcaagtgt tccggctgtg
    24421 actaagtttg ctaaaactgc ggcaatccct gccacgatcc cagtaccgac aaatgcagga
    24481 atcattggca caaagatatt agaaatgtct tttaataccg atttgatttt agatggtttt
    24541 tgtttcgatt tttgtgccgc tttcatttct tgtgcccgtt cgtttacacg gtcttttcca
    24601 gatgctgatg aatttgctgt agctgtactt acagaagaaa gtttttctcc taatttcacg
    24661 cctgccaaat caaccatttg ctgtgctact ttgttcactt tcccaggtcc gatgatgact
    24721 tgaagctgtt catcttctac tacaccaagc actcctggaa tcgcttttaa ttcagagaca
    24781 tttacaagat catcattgat gatcttcata cgcacacgag tcatgcagtg gacaatgctt
    24841 tctacattgc ccatgccgcc tgccccttta taaatttgtt ttgccagttc ttccaaagtc
    24901 agttcgtttt ttgccatggt cttttccccc tcataaggtc ccttttacaa atccgtttgc
    24961 ttcagctaat tttgcttgag cttcctcttt atcactattt gtcaaaatca tgacgatagc
    25021 cagcttaaca ttttgatctg cttcttcaaa gtacttttca gctgtttcgt aatcagcttc
    25081 tgtcgcttgc atgatgattc gttttgagcg ttcgattagt ttttcatttg ttggtttgac
    25141 atcgaccatc aagttattga atactttacc tataccaatc atactgatag tagaaatcat
    25201 attcaagata agtttttgtg ctgttcctga cttcaatcga gtagagcctg tcaaaaattc
    25261 tggacctgca tcgacttcga ttgggaaatc cgcgtgttta ctgatttcgg cttgtttatt
    25321 gcaagaaatc gttcctgtga cagcaccgat cgattttgcg taatctaatc caccgatcac
    25381 atatggtgta cgaccgctag ctgcgatacc aataactata tcattttttg tcaaattcag
    25441 cttgattaga tcttcttgcc ctagctcata agaatcttcg gccccttcga cagctacagt
    25501 cattgcttct tctccaccag caattagacc tatgaccatt tccggttcta caccgaatgt
    25561 cggtacgcat tcagcagcat ctaacacacc tagtcttcca cttgttccgg ctcccatata
    25621 aatcagacgt ccaccttttt taaaggactc aatcgtgtta gcaatcactg gttcgatact
    25681 tgtcagttct ttttcaaccg cagcggccac tttctgatct tctttgttca ttagttgaac
    25741 ggcttgagaa atactcatct catctaatcc aaaagtttct tggtttctgc gttccgttgt
    25801 taggttctct aaattgattt tgctcatttt tatcttcctt cttttcttat aaattgatag
    25861 ttcataccag ctttgatttg gttgatcaat ggtagctctt ctttgataac tttagctact
    25921 acattcactt tttcatccgc tggcaaatca tatttggtta attggatctc acccatatag
    25981 cgcaaatact tttcgttatc taaagtaata gaccctttca tacgcgtagc tgtatttctt
    26041 gctgggatag gcggaatctc tcgaaaacgt gcatctacgc ttcgtatgac atctcttgca
    26101 tcgtcttgcc gattcgtatg cttccctaat atatattcgt aaaattcttc atctacaggt
    26161 tccgtatgga gcaagactgt ctgttctttt tggaaagaag caaattgctc ctgaacgttt
    26221 tctgacagac ctgcatctcc gatgtaaaca atatccgtgt tacttgctaa tagatctaga
    26281 gcgcctgcaa gaggatggat ccctcgatgt tcttccaaag ttggcaatcc ttgatatagt
    26341 gggcctctca actctgtatc tcctggtaca aaaccttgga caaggagacc ttgaattttg
    26401 agccattgat tttttttctg ataccattct ttgtccagcc ctgtttcggg acgtggataa
    26461 taattatgcc aagcttcaat ctgtgagaaa tcagcttctg cttctttcaa ttcatcgata
    26521 tctttaggcg tgatcgtgct agcattcaaa ctgattttca attgatgtga ccagtcggca
    26581 atctgctgat tggaaatatg ataatccatt cttaaacctg ttacaccaat tgctttcaaa
    26641 ggcgttagat cttctaatga aaaacccgct cgttccaatg cctctcctga aatatcgacc
    26701 atcaattcta gtttattctt tttcgcttcg cttcctagtt cgatcaatcg cttttgatat
    26761 gccgaaacat catcttctgg tatatgcatg gaagtgaaaa taccgacaaa gccattggat
    26821 gccatttggc ggatatactg tttcttctct tctgacaaag aatcgttcat aaatattgaa
    26881 aagccaaaca tattatccct ctttttctgt atccgtcttc atttctatga ctagagtata
    26941 tatctaaaga aacaaaattt caatactttt attaaaataa ttaaatttca tttctaaagg
    27001 ttgagtttat attatcaaaa gaattgtcat aacctaaaaa aggcactgct aagcaaaagc
    27061 agtgccttga aatattttat ttaaataaca caaaaacata attactcata agaaaccaat
    27121 tctgtattat ctaccatgaa tgtaaagaac ccctcattag gcatcggatg aaaataagca
    27181 ttgatcactc ttatcaaggc attatggcaa actaacagat agacattttc ttcgtcttcg
    27241 atgcattctt tcaataaagg aacgatccgt gcatacacat ctaagactga ctccccattt
    27301 gggaatcgta cagcgaacgc taaacgtgct ttttgaaagt tctcatcttt gcttggcagt
    27361 ccatcataat ccccaaaatc catttctacc aatcgttcat caacggtcag cggcaagctg
    27421 agacgatcag caactgcttg tgctgtatct cttgctcgtt gaagagggga atggatgatt
    27481 ttcgtgattg gaacaggcaa atctactacc ttttctgcta gtttctgtgc ctgcatctgt
    27541 cctttttcag tcagcggcac atctgcccgt ccgcaaacta atccttgtgc gttccaagtt
    27601 gtttctccgt gtctcgttac ataaagcatg tgattctctc cttcgttggc aaagttcccc
    27661 ttaaccatac cttgttgttc ttgagattac aagggttaga ttctctcaag agaaataatc
    27721 tcagtagata ctttatccag gaaggtttga tcatgttcca ctagtaacat ggcaggtttc
    27781 acgttcaaga tcagttgttc taattgttct tgattgaaga catccaaata attcaatggt
    27841 tcatcccatg tatatagttc agctggctgt gataaagatt tagccaattc cacttttttc
    27901 cgttggccca tactcatctg ctcgatcttg ttatgaaaaa catctctttc catcccaagc
    27961 tttcggaggt tgttcaaaaa tgcttggtag tctacttggt ttttctctgc aaattccgcc
    28021 aacgttcctc gattgtcttc ataattttgg cttgcataac taatgctcag atgttttggc
    28081 tggtattttt ctcctataac cttgccgttg aatgccccca gaagataatg gataatggat
    28141 gactttcctg caccgttagg acctgaaatc gccacccgct gatgaggctc gattgtaaaa
    28201 tgaattggct cgaataacag attttcatac cctaattgaa gatcttctac gcttaaaagt
    28261 cgcttatggt gagacgcttg gctattcatc gtcaaagaat cgatatattc gatatctttt
    28321 aatagttttt ctttctcgct gatctgggtc tccatccgat tcacgattgc tttggatcgt
    28381 ttcatcgtcc gtgcagcatc agcacccact gctcctttat tcactcgtct agattcagta
    28441 tcgatgaatc cgacttgttt ctttgtttta tctccttctc gggaacgaga ccattcggct
    28501 ttttcagctg ctgttttctt tagcctactg acttcttttt tcaatttttc attttgagcc
    28561 atttcaaatt catcacgaag ttttttctgt tcttcataga tagagaaatt cccttgataa
    28621 agttccagtt gacttttttc gattgctaaa acatggtcca ctacttcatc gataaatccc
    28681 cggtcatggc tgaccacgat gaagccttgt tttttctttt tcaaataagc cgctacttgt
    28741 tttctaccag agatatccaa atgattcgtt ggttcatcga ttaacgggaa atgagtgtca
    28801 tccacaaata aaagtgccag taggactttt gtcttctctc cccccgatag tgtgctgaat
    28861 tctctccata agatttcagg atctgtttgc atcaattgga gctctctttc gatttcccat
    28921 atctcaaaat ccgtaatatc atttaacacg taataggtta aacgttcttt atcttttgtc
    28981 tgttgcggga aataggcaaa ttcttgctga tggattactt gcccttgata aggtagtttg
    29041 ttttgtagaa tattcagtaa agttgtcttt cctcgaccgt ttcgtccgat aagtcctagt
    29101 ttccattgtg tgtcaaaatt tagatttgct tgttcaaata ataatgtgcc ttggctgtcg
    29161 tagccgaatg tcagattttt tatttcgatt ttagacattt tccatcacct cgtaaaaaaa
    29221 gaccagtcct attttcagaa ctggctaaag aggatgcaag ggttggatac acacaaaaag
    29281 acccatacat cgaaaaaacc aagccaatcc cgaaaatctg cacactgctt ccttgtctcc
    29341 acaaggtaca gtctgaatgc agctttcatc aatcgactta atttttcaat gcacggatcc
    29401 ctcactttgt cctatatttg aaattacgat agcataaaga aaatgatttt gtcaactact
    29461 tcgggaggat ggtgaaaaat ctgctaagtg tctgtcctaa gatttttgtt ttttctaatg
    29521 tttgcctgtg ttccattgct tcttctaaac ctattggacc caaatgaata cttaagacaa
    29581 ttgggagaaa atcagaaagt ccttctagct cttggtctct acttccgcaa atagcgatta
    29641 ttggttttcg atattttttt gcaagcactg ctacaccgta tggaactttt ccgtggatcg
    29701 tttgctgatc gatccgccct tctcctgtaa tgatgacatc tgcttgttcg atcttttttt
    29761 ccaatccagt gatttggctg actaaatcga aaccagaaac catcttcgct cccaacaaaa
    29821 aagggctcca ccaataccgc ctgctgctcc acttcctgga atatcatcta aatccacctc
    29881 ccagaaatct tttatttgct gagcaatctt tcctgcttgt ttatctaaga aagctagcgt
    29941 cgtatctatt cctccttttt gtcttccaaa ttgccaagca gctccttgtt gacctgtata
    30001 tggattggta acatctgcag cgataatcaa ttttacttta gaaacaagaa cgtttcttcg
    30061 atcaaaatga agttttttag tagataataa aggatttcct tctgtgtacc cttctaaaga
    30121 agcacccaag gattggagta atcctagacc accatcgcta cacccgcttc ctcctaaagt
    30181 gacaataatt tgttctactt cttgaagcag tgcatcttta ataagttctc ctaaggcata
    30241 actggaagca agtcggatag tttgatccgt tggtttatca agtagatcta accccaatgc
    30301 ttgtgcagat tcgatgactg cggtgttttt tccttgccaa gttgtcaata aatagctgat
    30361 ttttcgctga cggaataaga gatccatccc atcaatggta cgccatgttc ccctgagcgc
    30421 gtaatagatt gcttctgcag tattttctcc gccatctgca atcggcacat tgatttttct
    30481 tcctttacga tcttcccagc catttagaac tgcctgattt agttcaaatg aagaagcact
    30541 tcctttaaat gaatcaattg ccgccaaaat atccatctgt atccctcact ttcttcttaa
    30601 gtaagacact ttttttcatt tttttcaaac aaaacaatgc tattttcttc catttttcta
    30661 tatactaaaa gggaactcat tgaataaagg agagaaaaaa catgaaaatc gcaatagctg
    30721 gggccggagc aatgggcagc cgaatcggat tgatgctaca tcaaagcgga aatgaggtcc
    30781 tcttgatcga tcgttggcct gctcacattg aagccattcg tacaaatggg ttgattgctg
    30841 actttaacgg taaagaagtg gtcgcaaaac tgccaatcta ttcaccagaa gaaatcatcg
    30901 aaagcaacga acacgtggac ttgatcgtag cattaacaaa agccaatcaa ttagatgata
    30961 tgttttgttc gatccaatcc attattactg acaatactta tgttttgtgt ttactaaatg
    31021 gattaggtca tgaagatgta ctggaaaaat atgtgccaaa gaaaaatatc ttatttggga
    31081 tcacgatgtg gacagctggt ctagctggtc ccggaaaagt cacattgtta ggtgatggag
    31141 aaatcgaact agagaacttg gaaccagaag gcgaagcatt tacaaaaaaa gttgtagaag
    31201 tctttcaaga agcaaattta aatccgatct atagccataa cgttcgttat tccatttggc
    31261 gaaaagcttg tgtaaatgga acattgaatg gtttatgcac gattttggat tgtaatattg
    31321 ctgaactagg cgcgcaaaaa gcggcagaga gcatggttcg aacaatcgta tctgaatttg
    31381 cttctatcgc agcaaaagaa ggaatcatac tagatcaaga agaagtgtac caacatattg
    31441 cttctactta tgatcctgac aacatcgggt tgcattaccc atctatgtac caagacctga
    31501 tcaaaaacca tcgtttgact gaaatcgact acatcaatgg tgccatttgg cgaaaaggac
    31561 aaaaatatga tattgctaca ccatattgtg cctttttgac ccaattagtc catgcaaaag
    31621 aaggaatcct tggcgcagaa taaaaggctc tctgatgaga atcagctgaa tcagcagctg
    31681 gttctctttt tttaagccca ataaaagatc aaaaagaaaa cacaactctc atgatgccat
    31741 aagaattgtg cttgtttgtt tcagtacata atctcttcaa aatgtaggtt ttttatttgt
    31801 tttcaacaga ggagaggtca tattcgtatt gctcataaat agtggaatcg ttagtgataa
    31861 atcgttttgc ccaattttct gcatcataaa attccaatag ctctgatagg attggcttaa
    31921 atggtgtatg cagaaattcc ggtaattcat ctaaatcacg ttctcgaagc aaaaaaatat
    31981 tttcaggacg ataaaaatga taatgagcaa tcgcttgatt atccgtcact agtttctttt
    32041 gaaaatacat ggattcaaat gtccgcaaag tcactccttg ctgaccctcc cgcaacagtt
    32101 ccagaatccc gcgcgattcc cctgtttttt tcaggtactc ttcataagta agatatccag
    32161 gttgttcatt ccctcgatgt ggaagaatga aatagttggt cgtaacatct ctttttataa
    32221 attcctgctt atagctttct gctcgttctt ttctcccatt attcgttgca ccaaaaaata
    32281 gatccgtctt tggttcgcta gaagaaaaat tcatatgttt cgaataaaat gaactattat
    32341 gtttcagccc aagttctttt gcttccaaaa aatcaaaatg ataaatctca tcgattgccg
    32401 gttcatcttg tgcctgcttc agcatcgcct cgtgttctgc tttgaagtga ttccaaaaaa
    32461 ataacacaat ttttgcattg gtaaatgggc gcacgcgtcg agccatctcc atatcaaatc
    32521 cataatctaa aaaaacgatc agctgataat ttgccaactg ttgtctagct gatttaatga
    32581 attccgactg tagtaaatct tttccggacc aaacatctaa agagcggatg gaaggcaaaa
    32641 aataaagtga tttatttttt gcaactagca gtacgtcatt tttgttcatc ttttccgcct
    32701 cactttctct gtcacttttt cctatgatag cctgtttaaa tagtaaaaag ccagtaaaac
    32761 gtttcctata tttgtatgaa aatttaacat ttgtatgaaa atatgatgaa ataaatcatt
    32821 cttctattaa aattcgccta aaagttttct gaatagttgt aattgtctga aaatttgtta
    32881 tcattagtca ttgttaaata ttgctattta ttcttaatat aaattttgat tgtgaattta
    32941 aaagaaagag gtcatttatg gaagataaaa aattgaaaaa acaacttagc tccagacata
    33001 tcaccatgtt agctttaggt ggagcaatcg gtgcaggtct atttaaagga agtggcgaag
    33061 cgattgggat cgccggccct tctgtattga ttgctttttt gattggtggg ctgattttat
    33121 atatcgtgat gaaaggtctg ggaaaaatcg ttttaagcgg tggcgacacg catcacggat
    33181 tatctggttt gatacgccct tatctaggtg ctcattctgc tgattttact gattgggtct
    33241 actggtctat gtggattatc aatatcatcg ctgaagctgt tgcagctgct tcctttttgc
    33301 agttgtggtt cccgcacatt ccagcctggg tatttgtttt tatgttggct gttttaacta
    33361 cgatcatcaa tctttattcg gtacggttat tcgcagaaac agaatattgg ctggcttttg
    33421 ctaaaatcag tgtcattatc ttactgatca tttttgctac ttatcttgtc ggtcagcaaa
    33481 tgttgggcac aggcgttttc cctacccttc agcaattgac tgaccatggt gggtttactc
    33541 ctcatggtat gaagggaatc atcagttctt tgcttgtagt tatctattct tacggcggtt
    33601 ctgaactgat tgctatcacg gtaagcgaag cagatgatcc taaacgtgcg attcctaaag
    33661 caatcaaagg tgtcatggga agaatcattt ccttttacat cattcctttg tttttgcttt
    33721 tgattctttt tccttggaat actttagcag gcacgaatgt cagtcctttt gtgatggtat
    33781 ttgaaaaaat gaatatccca tttgcagcgg atatcgtcaa ttttgtgatt gtccttgctt
    33841 tgttctcatc tatcaattcg ggtgtgtatg catcttcaag aattttgttc ttccgtttga
    33901 aggatcgaaa aggttcctct agaaaactag ctgttttaaa caagcatcaa gtaccgcaac
    33961 gtgctgtttt attttgtacc agtgttcttt atcttggtgt agctctttct tattttgtcg
    34021 gtgacaaatt atttggctat ctggcaggtt ccctttcgta tacagtatta ttgatctgga
    34081 tcattatcag tgcggcatcc tttgtactgg cactaagaaa aggaacatta tgggataaag
    34141 gaatcagctt ttttgcatta gctgtcttag gattgatttt ccttggtatc ctgttcacga
    34201 actccattgg ggtaactgta ttgactggcc tgctttacct gttcatttat ttcagttatc
    34261 aaaaaaagaa tgatgcgttc gtattgacga atgaatgaaa tcgatagaaa attttatttt
    34321 atttatgtgg aatagatgga gctattgaag aaaggagttg tgacaaaagt cttgttgcaa
    34381 ctcctttttc cgaataaaca gtctcatgac ctcttggtaa acggtgttca aaaaccctct
    34441 gtgcaaaata attgattgtt ctccatgctc atgacatgat agaagaaagg aatgaaaaaa
    34501 aggagtttgt tttaaatgaa aaagtattgg aagtttttgt tgatgatcgg tgtttcaacg
    34561 gtagttatgt ttggtatgat gtacttgaat gtctatgcgc tcgatcatat cttcttcagt
    34621 cgtacacgag tattcatggc gttgatgatg ggtgcagtca tggcagtcat catgctgttg
    34681 ttcatgtgga aaatgtatga aaacaaaaag ataaatgtta tgatcttagc cgctagtctt
    34741 cttgtttttg ccggttcctt gtttatggta cgaagccaaa ctactgtcaa cgacacagct
    34801 tggatgaagg ccatgattcc tcatcattct atcgctatcc tggcaagtaa acgagctgat
    34861 ttaaaagatc ctgaagtaaa aaaattagcg gaagaaatca ttcaggcaca agaagaagag
    34921 atcgacaaaa tgaaaaaaat gatcaaagaa atggaatgac cattatccgt ccaaataaaa
    34981 aaagaggatg ttccagaagt tatcagcttc aagaaataag aagaagctac ttctggaacg
    35041 ccgtgaataa ggggttgtga aaaagctgcc ctgcatcaag taataagaac agccaaacaa
    35101 aaatagcttc tcctattttt cgtttggtta ggcttattac cgcagatgca agcttttgaa
    35161 caccgtttat taagaggttg taaaatcagc gttctgacct gagtattaga gagacaaatg
    35221 gaaaaatagt tcctcatatt ttgccatttt ttgagctaat accgagggtc agctgattga
    35281 acaccgttta tcgagaggtt gtgaaaaagt cgcttagttt cgcgtattaa gaaaaatttt
    35341 gtgaaatggc tttccacatt tttgtataaa tttggcttaa taccgagaaa ctggcttttg
    35401 aataccgttt attcgtaaaa gggattgtga caaaagtctt gtcacaatcc ctttttatgt
    35461 ttttattgtt ctaattgcgc tgtcttgctt actgcttctt gcggtttcac aaattttttt
    35521 gagattcccc aacctgtgaa ggcactgacc atcgaaaaca caggagaaag caaactgaaa
    35581 aatacgaatg gcaagtaagt gagtgtagga ataccaaatg tacttgctac gaaacttccg
    35641 gcaattcccc aaggcactaa gtagttgatt actgttccac catcttctag cgttctacct
    35701 aatacagttg gatcaaatcc tgctttttca taagtttctt taaatgcatt accaggcaga
    35761 ataacagata ggaattgttc accaataaaa atatttactc cgatacttgt catcaatgtt
    35821 gtaaaaatca aatttggtgt gttcgtcatc tttcttgata ctcgttccat cacggttgag
    35881 atcaagccaa attcgatcaa caatccacct aatgacaaag ttagaataat caatgacaca
    35941 gtaggcatca tactttcgat tcctccgcgg ctaagcagtg aatcgatttg ttggtttcca
    36001 gtatttgaaa caaaccctga ttcgatgacc ccagccaact tcgttaagga agtttgtggg
    36061 ttttgaataa aaatcattcc tactgctaca gcgatattca acaaaatcgt taaaattgcc
    36121 ggcacctttt tccatgcaca cagtaacatt aaaaataaag gaatcagtga ccagattgaa
    36181 atagtaaagt ttgcttctag aacatcagtc acttcacgaa tagatgaaag acttgcggct
    36241 ttacttgtgt gtcctaaaat catgaataaa aagaaagaaa caacaaatgc cgggacagtt
    36301 gaccacatca tatgcttgat gtgtttgaac aaatcggcat caacaatagc tgctgctaga
    36361 tttgttgatt cggataatgg agacatctta tctccaaaaa cggcacctga aacaatagct
    36421 ccaacaacca gcgctggatt taagcctagt gttgtcccaa taccgaaaaa tgcaatccca
    36481 atcgttgaca taacagtaaa ggcactccct acagcgctac ctacgattgc acacacaaca
    36541 aatacagaag ggacaaacca ctggacactg atcaatttga acccaatgac cattagagtt
    36601 ggaatgatcc ctgcttgtat ccatacagca atcaatgaac cgactaaaat aaaaataaag
    36661 attgggatga ttcctggttt gatgccattg atgattcctt cgtgcagcca atctgtcggg
    36721 tatcttttta tcactgcata caacatgacc attccgatcg ctgctaagat cgtgatatta
    36781 ggtgagacct ttaatccgac aacgccaatc gcaatgccta aaacaataac cattaataca
    36841 agtgttgctt ctaaaaaact tggtgttcct ttttttccca tgataatctc tcctttttta
    36901 gttgttctta tgttctaaaa aagttaagat atcggattac tccgccgcaa ttcatccgcg
    36961 attcctcctt tataaaaata aaaagacctg ttttaaacta aggacgaatg actccgcggt
    37021 accaccttaa ttaaaaacag atctgttttt cactttcaaa cttttattca aatgtatgga
    37081 ctttccatgt aattcgtcaa ttaggcttga tcggttcaca gcgaccaccg actttctgaa
    37141 caaaacacct aaccgctact gcgtgaaaag ttgacttgta cgaagtttac cttccataag
    37201 atcatttgtc aatgaaaaag aaaatatttt ttcatttttc tgaaaattat ttttataact
    37261 ttcacacaca agtttatttt ttactagaaa gtagcgccct cttgtttttt tcttgctact
    37321 atttcttgat gttcttgctt gattctttct aatagctttg gctctttcaa cagatcaaga
    37381 gctgtattgg cgagtagttc tgctgcaatc gcaatagaag caaggccttt gtcactttta
    37441 gcagcagctt tgaattcttc tgtgtgtccg gcaatatatg tctcagagat tgctaccgta
    37501 ggctggattg ttggtatgac ttggctgaca tttcctacat cagaagaacc gagacttgtt
    37561 ctttgttccg tttctatttc ttcatctgga acacctgctt cttttgcatg ctggaagaat
    37621 aagtcatcaa aagaaggagt aacgatgaca tcatcaactg cattttggaa caatccaaac
    37681 tcaaaagtcg tgcccgtact tatcgcagca cctcgtacga tattttccac tttttcatat
    37741 actttatcta atgtttgccg atttcctgca cgtaaataga aacgtccagc agcgtaatct
    37801 ggaatgacgt tggcagctac tcctccgtct gtaatgatcc catggatatt gacatctttt
    37861 ggcaattgca agcgtagagc gttgattcca ttaaacactt ggatcaatgc ttccaaagca
    37921 tttactcctt tttcaggtgc tgctgctgca tgggaagcga caccgtaaaa tttgatgtcg
    37981 actggatcat tcgctaaaga ttctgtcgtt ttcccataac gaaaagctgg atggacgcat
    38041 aacgctacat cgacatcctc aaaaaaacct tctcgaacaa agctgccttt agctgatccg
    38101 ttctcgcccc cttcttcccc tggggtgcca tatacacgga tttctccacc agtttcatca
    38161 atgaattgct tcactatgct ggcggctaat acggagtaag taccaaacaa attatgcccg
    38221 catgcatgac caatacctgg taaagcatcg aattctgcca aaaaggcaat tgtgggaccg
    38281 ggtttattgg aaatataacg tgcatcaaag gctgttcggt gtccagctac ttctttttct
    38341 acccaaaacc tttctttttc taattgttta atcaacgctg ctgaggaata aaactcatag
    38401 ttacttactt caggatgttc gtggatatct agagcaagtg cttgatattc tggtaaacga
    38461 tattggatta gatccttcaa ttggtttgtt gagattgttg ttgtcataaa aaattcctcc
    38521 tatgctagtc atttttctta ttttctcccg aatgtttccc atgcaggcac gcttgatcct
    38581 tttgatgttt tctcgattac tttgactgtg tcttctgttt gataagcgtc tactattttt
    38641 tgatacgttt tattgttttc atcttctttt cttgcaacga tgatattcac ataaggacgt
    38701 gcatggtcat ccactggttc taagaagatg gcatcagaag caggattaaa tccagcatct
    38761 acagctacac cgctattgat cactgaaatg tctacatctg acaaagcacg tgctgtttgg
    38821 gaagcatcta attcagaaat gtctagattt tttctattct cggtaatatc agaaacagtg
    38881 ggcgcttgtc cttttgcctt atccactttg atcaatccag cagtttgcaa taacagaaga
    38941 gctctgccgc catttgtaac atcattaggg attgctactt ttgctccgtc tttgatatca
    39001 gctacatcct tcaaagtgtt agaataaatt cccagcggtg cattgacagt atttccgatc
    39061 gatactaaat cagttccgtg ttctttattg taattgtcta aaaagaattg atgttggaaa
    39121 gaattcaaat caatcgatcc atctgctaaa gccacatttg gttgattgta atctgtaaat
    39181 ttcacgtatt ccaaattaat gttctccttt ttcaaacggt ctttcacgtt gtcccataca
    39241 tctgtatctt ctccaataat ccctagtttt acgatagttt cttttttgtc agttgtatct
    39301 gcttttcctt ggctacaccc tgccaaccaa ataattgcta caaatgtaat gactacaaaa
    39361 cgaataattt ttttcatttt ttctcctcca ctttcaatgt gtaatttttt taatcagttg
    39421 attactgata aattgactta aaaaaactaa gattagaatc aataatgtag ccacaatcgt
    39481 tacatctgtt tggaatcgat tataccctct cgatatagca agattcccta atccgcctgc
    39541 acctactgct ccagccatgg tagtcagtcc gatcacgttg atgatagtca acgccgagac
    39601 ccgaatgata ccaggcaaac cttctaacaa atacacacgt aaaatgatac cgattggact
    39661 ggttcccatc gcttctgccg cttcgatcac cccaggatca acttctagca gtgcgttctc
    39721 gatttgacga gcaaaaaacg gaacaactcc aaaaatcaat ggcactaaag ctgctttcgc
    39781 accaatcgtc gttccaacta agaaacgagt agtcaatgct aaaagagaaa gcaagataat
    39841 gaaagggatg gaacgaatga tattgatcag cttatcaagt atttcaaata gcagacggtt
    39901 agctagtaat ccattagggc gtgtcactac taacgtcaca cctaagatga ttccaatcat
    39961 cccgccaatg aatgctgtcc aaaaagacat atatagtgtt tgcttcgtcg cttcgacaaa
    40021 ttcatccgga atcaaataaa cattgggcaa atatgtttta aagaaatcag tcattttatc
    40081 ttcctccttc gatcactttg atacgactat ctaaatcgtt tttttgtaaa atatttattt
    40141 ttacaccaga tttgatcaaa taatccaatg cttttttccg ctgtttggtt tctccagcta
    40201 aagtaacgat caaactccct aacggcgttt cttgtaataa ctctacattg ccatataaaa
    40261 tattcgctgt tacttgatat ttgctgtaca gatgagcgat tagaggttcg ttcgtctgat
    40321 ttccaatata acttaattcc accagccatt tattggcgat ctgatcggca aaagcagaat
    40381 gggcaatgat cgtttctaat gcttggtcaa gatgagtagc tgttcgaata aaatctttgg
    40441 tcaattcttc ttcaggattg ctgaagatct ggatgctgct acctttttca acgattcttc
    40501 catcttccat aaccgctacc ttgttgcaga tttctttgac aacttgcatc tcatgagtga
    40561 tcaggacgat tgttaaacct aactggcgat tcaatttttt taacaatgca aggatctgaa
    40621 gggtcgtttt cggatcaagt gcactggttg cttcatcaca taataatacc ttaggttcat
    40681 tcgccaaagc tcgtgcgatt gctactcgtt gtttttgtcc ccccgacagt tgtttaggat
    40741 aagcagatgc tttttcttcc aaaccgacaa gttccagtag ttcattcact ttttgacgac
    40801 gttcctgttt cgattttcca gaatacttta aagaaaaatc aacgttgtca aaaatagttc
    40861 ggctttccat tagattgaaa tgctgaaaga tcataccgat ggcctttctt tcttttcgca
    40921 attctttggg agagagctga ctcagattcg tctgattgac aatgacttct cctgctgttg
    40981 gtttctgcag caaattcatc acacgaacta acgtactttt ccctgcacct gagtaaccga
    41041 cgattccata aacatcgcct ttttcaatcg ttaaatctac agaatctact gcctgtatct
    41101 ctttttcttt ttgtttgaaa catacagaaa catctcgcaa ttcaatcatt aaaattcctc
    41161 cttatctaaa aaaagcgtcc tcaagaaaat gaaaatgtca ttttcttgag gacgcttttt
    41221 tgcgtgttac cacctcatgt tcaagctgtg ttcacacaca actcctcttc aagtacgatc
    41281 atactctagc aagatatcgg tcgcagccgt catcgcctta catctatgct cgggatgaat
    41341 tgctcgatgg ccattttcca atagtcgttc cttgcttctt ctcagctacc gaagctctct
    41401 gtcaaaggtt cttctatcgt acttaccatt tcaatgcaaa taatattcaa aaaaaaagtc
    41461 cttttactaa cataaactat gtcagtaaaa ggacgacgta tcgcggtacc accttttttc
    41521 ggaagtttcc ttccctcaag cccaacatct caaaaagaga gattggcgtt cgttttaacg
    41581 gtcgaacagt tccgaatttg cctacttatc gacaaattat tctccaaggc cattttcagc
    41641 ttttcttact tgactcttct caccagccag agcctctctg caaagtttcc aaacttactt
    41701 tccttttcaa cgaaatcgat attttgttgt tgggattaat ctacatgagg aaaactgaaa
    41761 agtcaagtac gaaattcaaa ttattttttc tatatttatt tttctgtttt tttatttaac
    41821 atttcaataa cagttcgaag atcttttcct tccgcaagaa gtttcaattt ttccttttct
    41881 tcgacggtat aatttcggac aaaactggaa tcaggtatca aaacaacgcc taatcctgct
    41941 cgtgaagcag ctgttgctcc tactaaagaa tcttccactg caaaggctga actagcttct
    42001 aatcctgttc gttccaaagc tgtcagataa ggaatcggtg aaggcttgtt ctccgacact
    42061 tcgtctccga atgtaaacgt gtccaagtaa tcagctaatt taaagtgatc caagatatct
    42121 gttgctcttt tcgtaacagt ggtcgtagca atgcctagtt tcatatgacg ttcttttaag
    42181 tctgccaata tttcttttgc atatggtttt aagtggatgg ctccgcttgt cagctgttga
    42241 taaaaatatt cttcacgctt cgctcggact tcctgtactt tttcagggct acctgctgct
    42301 ttcactaaaa tatcaaaact ttgtttccag ttttttccgc cccaagcgtc aacgatttct
    42361 tttgggatat ggatatcaaa ttgctgaaat ccccaaagcc agccatcacg atacgttttt
    42421 tctgtgtcaa ctaacaaacc atctaaatca aatattgcac ctttcatcta tacattaatc
    42481 ctttccaaaa caatacacat agtttagcac gactggtcca aaaagaacag aagcaaagaa
    42541 ccagccttct cgtttataag agttcttgga atcgacggat atagattttc ttcacagctg
    42601 tcacaagcgc cagataagcg atgactgtag caaataacca taaccagtaa ttgccaggaa
    42661 gtggcatcaa gcctaattca gcaccaaaac ttgtaaaagg aaggacagaa ccgacaataa
    42721 ttcctaatgt agtgataaca aacatggcaa atgttgcgtt gctttggata aatggtactt
    42781 tcggtgtacg cagtgcatgg agcactaagg tttgtgtcca tagtgattcg acaaaccatc
    42841 ctgcatggaa taatgcgatg aaaatcactc gctgtgaact atccaatgta tggaaacttc
    42901 cgcccactac agcaggacaa ataacaaaat acatcaacaa gtaagtagta atatcaaata
    42961 tcgaacttgt tggaccaaag taaaccatga attccccaat actagatgca ttccattttt
    43021 ttggctcgtc caaatattct ttatccatcc gatcccatgg caaggaaatg caggaaacat
    43081 catagatcag attcaaaaac aaaagttgta aaggcagcat tggtaaaaat ggcaggaacg
    43141 tacttgcaat cagcacggaa aacatattgc caaaattaga acttgctgta gccttgatat
    43201 atttcatgat attcccaaaa gtttctcgtc cagaaagaag gcctctttcc aaaatcgtca
    43261 aatctttttc taaaaggatc acgtctgcag attctttcgc aatatccaca gctgtatcta
    43321 cagaaatacc gatatcagcc actttcattg caggagcgtc attgatacca tctcctaaaa
    43381 atccgacagt atgaccattt ttacgtaaag ctgtcgtcaa acgtgctttt tgctgaggat
    43441 tcaattttac gaatacttca tggtcttcag ctacttgtgc taattcatga tcactcattt
    43501 ccgagatttt ctcaccggta accaattcat tgatctctag acctacttga cggcacactg
    43561 aacgtgtaac taattcgttg tccccagtca gaacttttac agctacacca tgttctttca
    43621 gagctttcaa cgcttgtttc gttgtttctt ttggtggatc aaggaaagca agataaccaa
    43681 tcaaaaccat gtctgactca tctttgactg aaaattctcc aacgacgctt ggattggtct
    43741 tttgtgcgac accaatcact cgtaagccat cttcattaag tgactgtact tttgcaagta
    43801 cggcttcttt tcgttctttt gttaatggtg taacagtacc gccaagatca ataaatttag
    43861 aaatgttcag catttcttca atcgcgcctt ttgtgatcat ttgtgtttta ccagctggat
    43921 cagcaaccac aacactcata cgacgacgtt caaaatcaaa aggaatttca tccacttttt
    43981 gataattgat cttatctgta tctaaagttt ctgttgcttc atcaatgata gccacatcta
    44041 acaaattttt cagccctgtt tgatagtagc tatttagata cgcatggcgc aaaacacgat
    44101 catcttcatt tccttcacaa tccatatgat attcaagaat gattttatct tgtgtcaatg
    44161 tccccgtttt atccgtacat aacacatcga ttgcaccaaa gttctggatg gcattcaaat
    44221 ttttgatcac tgttcctttt ttggccatca cacttgctcc tttgaccaaa ttcgtcgtaa
    44281 cgatcattgg aagcatttca ggtgttagac caactgctac agatagtcca aaaagaaaag
    44341 cttctagcca atcccctttt gtaagcccat tgatgacgat aactgctgga gccatcaatg
    44401 acataaattt gatcagtagc atggatgttt tatggatgcc taattcaaag cttgattgaa
    44461 ttggtttttc agatagcgtt tctgctacat gaccaaatag tgtttcattt ccaacagaaa
    44521 caatgattcc ttccgcactt ccactgatga cattacttcc cataaagaca agattttcgt
    44581 aacttgtttc gctttgctga tcgtcttcac atactttcgc atgcttttct actggatagc
    44641 tttcccctgt caatgctgct tgggaaatga ataaatcctt tgcggacaat aaacgcatat
    44701 ccgctggtat catatcccct gctgaaagcc gaacaagatc tccacagacg atttcttcca
    44761 taggaatctc tgtgtacttt ccattacgtt ttacagctgc cgttactttc acaagtgatt
    44821 tcagtttttc agccgcttga ttggaacgta cggactgaat caacgtcatt gtcccgctga
    44881 cgataaccat agtgaagata atggctacac cgaaaagatc tttatctcca ggagctgcta
    44941 atacatattc cgtgatgaat gaaataattc ctaatgcgat caacactaat gtaaatggcg
    45001 tgatgtatgc tttcaatatt tctacaatga atggtgtttt tttgccatat gaaatcgcat
    45061 tttcaccgta attttctctt gaacgttcga tttgttcttc tgtcaatcca tttgctgatg
    45121 catggaatag ttcaaataat tcttgtttcg tttttccagc aaaagctgca tagatttttt
    45181 gtgtatcttt ctttttttcc atctcaatct ctcctttgtg tccaaaagac agctgttctc
    45241 gctgcttttg gtctttagct attcatcgga tcgatagaga aaaaactgaa aggggctgag
    45301 aacagataga taatagccct ggcctttcct ctagatcctt gtttttcgaa tgactgtcat
    45361 ccatttgttc tcatctcctt tactaagtaa ttttaattca tgacttccaa tcatttttcg
    45421 aatagttatt tttccaatta gaccacctcc tttttatttt tcaccgatgg ggatttgcgg
    45481 caacaaaaaa acctctcgcc aaatactcag cgaaaggttt gaaaaagcat attaaaaaaa
    45541 gcttctcaga tctcatcgtt gagttttgac actgtacaac gtaaaaagca gatacctgct
    45601 tttagctacc ttatgaaaag ccttatctcg acaattcctg ttctacccat tggcgtctct
    45661 cgacgttttt gggcagtagc ctatgtttgt ataggagcct cacctaacaa atcttattcg
    45721 gttttccttc gttaatataa caactaaaaa agaggatgtc aaatcaattt tccatgtttt
    45781 tcatactttt tttaaaatac acacgttata ttcctgtctc acgcggtttt atttgtctca
    45841 ttttccacct cccgctataa tagaaatata gtaggaaacg aggtgctgtt atggaaagaa
    45901 cacttgttat tatcaagcca gacggcgtga gacgccattt agtcggaagc atcatccaac
    45961 gttttgaagc aaagggactg gccattgctg aaatgaagtt tgaaactatg actcctgaat
    46021 tagcaaaaga acattatcag cacttgactg agcgcagttt ttttgatgaa ctgatcgatt
    46081 acatgacttc cggtcctgtc gtttatcttg tgctggtcgg cgaggaagtg atcgatatcg
    46141 tccgtaagat ggttggagca acaaaagctg ccgatgctgt tccaggtacg atccgaggag
    46201 actacgcgct gccggggact gaaaacatca ttcacgcttc tgattcccgt gatgctgcgg
    46261 taaaagagat cgcccgcttt ttcccgccat tcgatataaa caaaccgtct gaaaaagcgg
    46321 cgaagtgata caaattctaa actgctggtc tagttgctgg gttcagcaat ggccagcagt
    46381 tttttctcta aggacctccg ttgattcttt cctaacatat attcgagcac tgtgaagaat
    46441 tcttggtagt ctttcgtctt ttcttcccct aaagcagcag aaatcaatct ttgataataa
    46501 tctgccatca atgtttcata gatcactgta cttctttctt tatgtgataa gctccgtttc
    46561 atatcttcat tcacactacg tgcctttttc aaccgaccat tttctatata aaacgaagtc
    46621 aggttcatta aaaaagtaaa gagatactgc tcatgattgt tcaactgtgc taatcgtcgc
    46681 attctttttt tgattttcaa ataattgttc tcaatgaacc gatcactgaa tatccaagga
    46741 aaatcagcta gaatagatag ttcaaattga ccatagtctg gtatctgcat caagtattct
    46801 tcaatgattc ggcattcata acgtaaaaat tcaaattctg tctcagatac ttctgttttt
    46861 tcgaccatgt gaagattcaa aaccaaataa tacagatctt ctgttttctt aaaatgccta
    46921 cggttattgc tgatctcttt ataaggatca aagctgtctt cttgtacccg atctagcatt
    46981 cgtctttttt tctttaactt tattggttca tccagctggt ttcgcatcca ttcatattct
    47041 gcaagtgtca tgttcattcg ctctaaaaat gatctcaatg ttacaaatga catttttttc
    47101 actgaatttg tctcaatccc gactagagaa gtcttaaaac agattccttc cgctaattgg
    47161 gactgtgtca acttcttgtt gactcgaagt ttcttgatca attcaccatc atacataata
    47221 gttctccttt ttaatttaaa tttttccaca ttcaataaat agatacgtta aaaaggaaaa
    47281 atacacgaaa aaaataaaaa aatgtttttt tcataaaaaa taccaacctt caagcattag
    47341 aatgttgtct aactactgaa ggttggtttg attgtttatt gattattttt ttgctgttca
    47401 acgtctgttc ttgttactgg atataagttg gttgttgttt tattaccatt ttttgaaaag
    47461 acacttgtcg aatgttcgcc tttttgcttt tcgattgctt cattacgttc cgcttcattt
    47521 ttatagtcat attttttcgg atcaatcgtc tcaaatccgt ttggcacata aaaccgcaag
    47581 agattttcct gattcagctt atctgaaaga cttaacgcag tcttgacttt ttcctgatct
    47641 ttggagattt cctcatcgat tcctgctgct ttcgtatcga tgatttctcc tgtctgatta
    47701 ttgtaagctt ttcctcctag gacggtgtat ttgggtgtca caaagttccc atttcgaaaa
    47761 gcaactactt gatcatgctg agaagataat aagtctgtac caaaatgaag ataatcttta
    47821 tcatcgattc ccaatagatg tagtaatgtc ggcaaaacat cgatttctcc accgtattca
    47881 tgattgactg tccctttagt ataaccaggc atatggatca tcaatggcac tcgttgcatc
    47941 tgtgcgttgt caaattcatc ccatgtatct ggatctttac caagagcgct tgctaaatct
    48001 ttattatctg tattcgagat cccaaaatga tccccgtaaa tcacaaagat tgaattttgg
    48061 taaataccag attttttcaa atacgtaaaa aattgttcca atgattgatc cagataatgt
    48121 gccgttcgaa cataattatc tactgtgcta ttgccagtat tcaaagatgg aaagtcgaaa
    48181 ttcttgtcat ccgtataata aggcgtgtgg ttggttacgg aaagaaattt cgtgtaaaac
    48241 ggctgttgta gatgctcaag atattgggca gattctctga ataaatcttt atctaatatc
    48301 ccataaccta acgtttcgtc ggattcatca aaataagatc gatcaaagaa attgtcataa
    48361 cctaagtttt tatatacatg atctctattc caaaaactag ctacattccc atggaaaaca
    48421 gcgcttgtat agccttgctt ttgtccaagg atcgctggtg cggcttgaaa gacattgtct
    48481 gacccaagtt ctgtgaataa tgagccttga ggtaaaccaa atgtgccagt ttccaacata
    48541 ttttcagcat cacttgtctt tccctgtcct acttcatgaa agaaattgtc aaagctgatc
    48601 gttgcttgat tctggaaaat actatttaaa aacggtgtga cttcttgtcc gtctaccttc
    48661 atattaatca aaaactgctg gaaactttct aaatggagaa cgatcacatt tttcccttta
    48721 gcgatcccaa atgtttcggg atttggctct gcataatgtt tctttgtata atctaaaact
    48781 tcatcaatcc cattactgct tgcatgcgcg cgaacactgc tagtcattcc tgttttgatt
    48841 ccgtcataaa tagtatacgc atcgattcct agatatttga caatatatga acggtcaaat
    48901 gttcgctgca gcaattgtgg acggttggct tcgctcagcg ctagatttcc tgaaaaaata
    48961 agccctgaaa gacaggtaac agcgatagcc atcggtttgc cgacagggtt gcttttgata
    49021 ggtattttct tgaccttcaa ccaaaccagt agcccaatga acacagcgat atccagccag
    49081 tagatgacat catggggctt catcaaagaa aaggagcttc ctgacaatcc ttgcgacact
    49141 ttcgaaaagc ctaatacaga tttgactgta atgaaatctg tgaattcccg ataaaaaata
    49201 atattcaagt acaacaaaag cgtatttaaa atatcaatga tcaaaagaat agctaacgct
    49261 ggctttggct ttttaatata caaagaaagg ccaaaaaaca ataaggtagt cgcaattggg
    49321 ttgatccaca agataaagta ctggatcgta ccttccacac ctaatgaaaa atctgcatag
    49381 taggcaatga tcgtcttcag ccagaaaaag aaaacagctg tcaaaacgat tgctaaacga
    49441 ttttggcaca attttttaag ttgtgtcacg tatatcactt ctctctattc acattttttc
    49501 ttattttgct cctgaaaaat gaaaatttcc taaaaaagtt gttatcttaa gattttttta
    49561 ttctttctaa agattattcc gtccactttt cacagcataa aaccgctgcg atgtaagcga
    49621 ttaaactaat gaagagataa aagtcttgtg gtgaccgctt cactccacgg tattcaaaag
    49681 ccagtttctc ggtattcgta caaaaaaaga ggctgtgaca aaattcttgt cgcagctcct
    49741 tatttcttga tgcaggacag ctttttcaca acttcttcct taaacggtgt tctcctgcca
    49801 actcctcggc cacaagtcac aatatttata aaacatgaga agctgttttt tgaaattgtt
    49861 ccttgtggct cagagttaaa cggcaggctc aagacctctt gatacacggt gttcaatcag
    49921 ctgaccctcg gtattagatt atgtcaggac gctaatttta caacctcttg gtaaacggtg
    49981 ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg aaaaatataa ggagctattt
    50041 tttgaaattg ctccttgtgg ctcagagtta aacggcaggc tcaagacctc ttgatacacg
    50101 gtgttcaatc agctgacctt cggtattagc tcaaaaaacg gcaaaatatg aggaactatt
    50161 ttgccgtttg tttctctaat actcaggtca aaacgctgat ttcacaacct ctgtttttca
    50221 ttgtccatag gattgatatt gtccttgtga tgactcattc gtaataattg aggcttgatt
    50281 ttcttcactt cccgttatcg tttgtccact gccagaatct gaaggacttg ttcctgtcga
    50341 ctcgtttttt tgagaagaga cagttgtttt cttgacttgt tcatttgtct ttttccattc
    50401 cgctaaacga tcggcgacca cttttttgtc tactttttca gaataagcgg tgatcacttt
    50461 tccatttttc aaacgggcta ctttgtcgcc aacatgagtc aaaagcaaaa cggtcaaatg
    50521 cttgtcttta aattgatatt gtctgagaga aatcgcacta agtacgtcat cgatattaat
    50581 aaattgattt tcttcttttc cttttggcaa ataaatgtcc aattcgcctt tttcgtaatt
    50641 ggcagttatt ttatactccg cccaccaata agttgagaat tcttttttga aattatctac
    50701 tgattctttg cttgctacga ttttttctgt ttctttctga gcaagatctg ctgtcatttt
    50761 tcctgaaaat gctgcggata aaataagcag taagaaaaaa ccgaataacc aaaagagaag
    50821 aaacggtctt tttttcctca tgctttcctc cactcctatt taattttgac tattctatta
    50881 tatacaaaaa atgaaataga aagacaaaaa agttgaaaaa gatcgtaaat aattgaactt
    50941 ctttttcaca aaatggtaag aatggagaat ttcacgcatt tgctctcaac tattctttct
    51001 taagcctcaa atccgttttt atctgatacg tctttgaacc aatgacccga ttttttgatt
    51061 gttctttttc catcttgtgc taagtctact gaaataaagc catatcgatt cttatatgca
    51121 ttggtccacg accagttatc catacatgtc cacatatgat agcctaaaca attggcacct
    51181 tcttgaatgg cttgatggac atatttcaga tgagattgga caaattcgat ccgataatca
    51241 tcgtggatca tgccatcttc tttgataaat cgtgcttcgt tttctacacc cataccgttt
    51301 tcagaaataa agcagtcgat atttccataa tgatctcgta cattgatcaa aatatcatag
    51361 attccttgtt catagatctc ccatccgcga taaggattca ttttacgacc aggcatttca
    51421 taattgtcga aataatcctc aggcattgga ccgtttttag tatcgattgg tgtttctttt
    51481 gcttttaccc ggcgtggctg gtaataattg atacctaaaa gatctactgt attttctttg
    51541 ataaccgtca aatcctctgc atggatcaca ggcatgagat caagttcttt tactatctca
    51601 atcaattcac ttggaaactc gccttttaca gctggatcaa ggaatgaacg attgaagaac
    51661 gcatctgcta tttgcgctgc tttaacatct tcagggtttg attcgtctct tggatagctt
    51721 ggtgtcagat tcaagatgat accaataaca ccaccttgct ccatttcatg gtaagatttg
    51781 atggctaacg ctgaagccaa cgcttcatga tagccaactt ggatcgcttt tttcatatct
    51841 gactcttctg gataatgcca tcgatataaa taacctgctt cgactggaac gattggttca
    51901 ttatgagtaa accatttttt tactttcgaa ccaaacaatt caaaacaact tttggcatat
    51961 ttttcatagg cttcaaccgt ttctcggttc aaccatccgc ctttttcttg cagatacatc
    52021 ggcatatcga aatgatacag attcacaaag ggttcgatac cgttttcaat caactcatca
    52081 aaataacgat gatagaaacg aacggcttct tcgttgattg ttccagattc atcaggtatc
    52141 aaacggctcc attggataga tgttcgaaat gaattatgcc cagtctgttt catcaactgt
    52201 acatcctctt gatacttcgt ataaacttgc gaggtttttt caggtcctac ttgatcaaag
    52261 aacttttgcg gttctttttt gtaccaataa tcaaaaatgt tctctccttt tccatcgcct
    52321 gaaatccttc cttctgtttg tgggccactt gctgcagaac cccaccaaaa atttgctgga
    52381 aattgatatt ttttcatcaa agcacctctt tttctttttt agttcgtttt agttgattcc
    52441 atgtatgata ttttccatca caatcacttt ttcattttct tcctcttctt ttttgattcg
    52501 ttttaacagc tgttctgctg ctcgttcccc gattttatct gttggtggcg tgatcgtgat
    52561 tttcggaagg atactcagat cgtttttatc taaataatca tagtgactga acgcaatatc
    52621 cttcccgatt ctgacacctt cttgattgaa acattcgatg gcaccaatcg acatattgta
    52681 attgctgaca aaaatagcag ttgccccttt ttctaataat gcttttgccc cgtaatagcc
    52741 gctttttcta gaatagtctc ctgtaaagac ctctaattgg atcgatggat cattttggac
    52801 cgcttctttg gctcctgcta aacgttctct tgctacgtag tctgtttgag tggcagcaat
    52861 aaatccgatt tttttatgtc cttgttcacc atgatgagcg atcacttttg ctacactttc
    52921 tcgatcattc actaatattg tatcaatacc tgctggtcct tctggacaat tcaatgcgat
    52981 aactggaata ctcatttttg tgagcatttc aaatccagac cactcttctt cggataagaa
    53041 gacaatcagc ccatcgatca catgcttcat caggtattca attttttgtt caattttttc
    53101 tggctgatcg gcaaacccgc ttaataataa gctataccca ttttcttcag ctactctttc
    53161 gatccctgag acaacttccg acccaaaacg gctggaaatc ccgtttatca aaagtccaat
    53221 agagaagctt cgattattct tcaacccttt agcaatgatg ttttctttat agtccaacgc
    53281 tgaaatcgct tctgctattt ttttcatgtt cttttccttc agttgctgac cattcaagta
    53341 acgggaaact gttcccactg aaacaccagc catcttagcc acatcacgga tcgatgccat
    53401 acattctcac tcctgccagt tacatttgat ttctctttct tgttgttcga ttatgatgac
    53461 cgcattcttt gcatagtgtt gcttgtcatc aatatccata taactaaagt cttcagtaga
    53521 gcaacttcct ctcactatta attatactta aacaagtatt tgaaccggtt catttttaat
    53581 atagcatttt tttaaaagat tgcaacactt ttttaaaacg ctttctgaaa gtggcggatt
    53641 ttttgccttt ttaaaatttt attctaaaat ttactctatt tgtgggtgtt ttgtgcgttt
    53701 ttctcttcca tccgtttgaa gttttacatt ccaatggtat aatttcttta tcctatcaaa
    53761 tgggggaagt attttgaaga aattaatcgt actatttatt ttgtctgcgg gacttttgac
    53821 attgactggc tgtgatttgt ttggcggctc tgaccaatcc tcggacgaaa caaccgattc
    53881 ttctgtctta aaagcggaaa aagcagatac caccaacagt gtatatacgc taaaagtacg
    53941 taaagatatg gatttatccg cgggacagtt gacatttaca gataaaaaaa tggaatggac
    54001 acgcacgtat cagacacaag gaactgattc ttctgaatca tctgaagaaa aaacagtgct
    54061 gacagatatc aagatcacta ccaaagatga cgaatatatt atttcaggaa aagaaaataa
    54121 aaaagaaaca acagtcatat ttacaaaaat cggtaattac cgtttgaagg atgaggatgg
    54181 caacatctac agtctatagt gccgtctgtt ggatcttctt ttgtttctcc ccttcttttc
    54241 tgctatagta aagaagcaag atgattgtaa aggagacgaa atggatgatc gatagtcctg
    54301 attattgtac atgtaataac aacaaaaata tccatacaga atttaatgac caaggaagct
    54361 tgagcatatg cgacaactgt cacaaactag tcaaagattc atttaaaaca tttgaatctt
    54421 atcctgttca aaattatgta aaaagtagaa gaagataaac aaatccaagc aaaactcact
    54481 atggctgatt tttatgaact tcaaactcag cttcttcctt tgatcaagct tcatcagtaa
    54541 aacaaacagt ggatcatttc agtttacaaa tcaaagagta aagatttatt tatttcaaat
    54601 atttgaatat aaaataacca aacgatagaa aggcttattc tacatcacgt agtaattttt
    54661 ctttcccgtc gtttggtttt ttatttttag cctaattctt gaccttttgc atgctggtta
    54721 tccgtaaaat attttccagc aggctttcct tccaattcag ctaatttttc ttggatctga
    54781 cggatcacct tttttgcatc ttctggattt tctacaaaat cgaatttatc cccatccact
    54841 tgtattttag gacatacatc aaaatcttca taccattgat tatagcgggt gttcaacgtt
    54901 tcataatagg tatataacgt ctcatcgctt tctagctgtt catagtcacg cccacgtttt
    54961 ttgatacgtt ctagcatcgt gtccaaagaa actttgatat ggaccatcaa atcaggccgt
    55021 ttttttggag caacatcatc taactcgttt agcatcgtat ctaataagct atcgtactgc
    55081 tgtacttcga tatccgttac ccgacctaaa tcagcgttta gatggaacaa caggctatct
    55141 tcatagatgg atcggtctag cacattgtca tcgttcacta aagcattttt cattgctaaa
    55201 aatcgcttgt tcaaaaagaa gatttgcaat aaaaaagcgt actgctcagg atttgaataa
    55261 aagagcggca atacttcgtt atcttcgaca ttttcataaa atggtttaga atcaatctct
    55321 tttgcaagca tatccgtcaa actgctctta cctgcaccaa tcgttcctga aatcaaaatc
    55381 actgacatac aacccttcct cttctataag tactcgccta cgtaagtttc aacaggcaat
    55441 gtttcaaaat catattcacg tacagcttgg tctgatttta aatacgtatg gagactttgt
    55501 gtaatcatca agttcgtagg taccgtctct tcttgtacaa tgatcatcgg ttttttcaac
    55561 atagttgcca cacctaattc gtaagccgtt cctggatcga ttgtttgatg ctcaaagtca
    55621 aggatagcaa caacaaattc tgcatttgtc agttcttcca tatctttttc gtatacttcc
    55681 tgcgcccatc cagcgctgaa tagttcataa ttgctttctt ggtgatgacg tggagagtag
    55741 aaacttgtga ctgttttgtt ttcctccaac gctttttcga tacgacttac tcgatcgatt
    55801 tgctcctctg aaaaaaatgg tcctgctaaa tatatttgac tcattatttt gcctccttca
    55861 ataataactg atttttaata gatactgctc gtaattcatt gaccagttcc aatggattgt
    55921 tggaaaagat tacttgatcc aaccattttt tatccataaa atcctctttt gcaaaagttt
    55981 ctaataattg ttgcaagccg ctgtaataac cgccaatatt caatattccg attggcttgt
    56041 cgggcgtcag accgattgct atccaagaaa gaagttgtga gaattcctcc aatgtaccta
    56101 gacctccagg gaaaacgagg acagcatctc ccttttcaaa taataatacc tttctttcat
    56161 cgatcgtttc tgtaggaata aatgtagtaa catcttttcc aggcaattca gtttcaaaaa
    56221 gcccattcgg atagatacct gtgacttttc cgttattttc cagtactgtt ttactaatca
    56281 ctcccataat cccggagtat gaaccaccgt aaaccagttc gatttcttct tgtgccatgt
    56341 attttcctaa cgtttgcgca ataaatttgt aactttcttt attaccaaaa cgggaaccgc
    56401 aaaaaacagt aagtttcata aaaaaacact ccctaactca aaagtctatc ttcattctac
    56461 acgtgttttt ttaaaataaa agactagatt ttgtagtttt ttagtggtat ataggataga
    56521 cgccactata tatagtattt agaaaaaaat catttttcag ccattttata gataaaacaa
    56581 aaataaataa cgtgttttca tcgatatgaa atgacttact tatagaagat actgggattt
    56641 cgtcctatat gccaataacg tgtattattt taaacaacaa atacttgttt cttttattaa
    56701 cgaaaaaatc attttgttct cgtgttatgt ttcactgata aatgatgttt ctctaaataa
    56761 aaaagccgac gaactaaacg atcaaaattt gatcattttt gttcatcagc ttctcctaaa
    56821 aatctttttg ttaacgataa atagctggat ttgtaaaaat atcacttgaa tcgtcactgc
    56881 tggaagaaaa ttcagtgata accgcacctg ttgcgcctgc ctggaactag tgtttgatat
    56941 tgggctcgaa cgtgtactga tctctagcat gaagaataat ttcttttttt actgtataat
    57001 aactttcttt cctttttgga atagtacagg aaagtttttt tgtttccttt ccttcgacat
    57061 aaggtatacc agaccctttc gacaacgaaa ggttctcatt tttccttcat cgtcatttca
    57121 aggagggtgc cgatgctctg gacagtttcg atcgctccta aaccaaaatc tgtatattcg
    57181 attctttcta actctgattc tttcatacca ttcctgtctc aaggtacatc tattgtactt
    57241 ttttcttgta atccattctg cctctcctaa ctaattgtca aatcatccca agatatgtct
    57301 tcttcctctt tttcttcttg gatgatttct gcattcggat ctactggttt tttcaataat
    57361 aaaatggtta ttcctgtgac aaaagaacca gctaacaatg caccaatgaa tgcccatggt
    57421 ctggtcatcg tagcgactgc aaacattccc gatgccggaa tacggctatc tgcgccccaa
    57481 aacatgctta atccgccacc tactgtccca ccgactcccg ttgctatgac attgcgtgcc
    57541 aagtcgttca atacgatagg gaaacatccc tctgtgatct gacagatccc cataggaaaa
    57601 gcggtcttca atgtatcgat ttcttgacga ttgagtatat ttttacgaat gattttccct
    57661 aagaaataag cgatcgtcaa gccgaatggg gttaccatcg aagctaaaat caatacagtg
    57721 attggttcat agattccttc tgaaaatcgt gccacacccc cttatccaga ataaatggta
    57781 atccagaaac agccgtgtat ctgcggtaat aagcctaacc aaacgaaaaa tatgagaagc
    57841 tatttttgtt tggctgttct tattacttga tgcagggcag ctttttcaca acctcttttt
    57901 ttatttatgt ttcataatca atatggtaag gatgcagctc cgtatggtag accgcctccg
    57961 aatattcaat catttcccca atttgcgtag acgatttccg tatccgtttg atgccgatct
    58021 gtgcgtctgt tttcagaatt ccttgttctt cttctgttaa aaatactgcc gagaaatcat
    58081 cagaaaatga gtcaatagta tatccttttt tcgtcagcaa acgatacaaa gattctttgc
    58141 caaattcttc tctgctgaat tgcatcattt cttgtggaag ataatgaaca aaataaatat
    58201 aaggctgatt gttcaaataa tataagcgct taaaacaaac agcttgctca ccgaaaaagg
    58261 aaaacaaagg atcttccttc tttatatgga ccaattgcaa atccagcgtt tctttccgga
    58321 cttcatatcg ggagttctcc aagatttgcg taaagcttgc cgctttggat aatcgattgt
    58381 aaggacgatt gcttagaacc gtcgtcccac gaccactttt ctttgcgaca tattcatctg
    58441 atgccagcag ttcgattgcc tttcggacag tgattttgct gacttgaaac agttcttcta
    58501 attcactttc tgtcggcaac atcgaaccga ctggatattt tcctgagaaa atatcttctt
    58561 taattttatc tgcgacttcc aagtatagta cacgtgtcct tttcataacg tcaccctttg
    58621 ctttactatt actaaaagaa tagcacataa aaaataaaaa aagaacacaa atcacatgtg
    58681 agaagtgtgt tctttttcat tcagctgctt taattacaag tttacgccat ttgaggcaat
    58741 tacttcttta taccaatcaa aagatttttt ctttgatcga ttcagtgtcc catttccttc
    58801 atcgtctaga tccacataga taaagccgta acgtttactc atttctcctg ttgatgcact
    58861 gacaagatcg atacatcccc aaggcgtata gcccatcaaa tctacaccgt ctgctactgc
    58921 attagccatc gcttcgatat gacgacgtaa ataatcgatc cgataatcat caataatcgt
    58981 gccatcctct tccatatgat caatggctcc aagaccgttt tcaacaatga ataatggttt
    59041 ctggtaacga ttgtataatt cattcaatgc gattctcagc ccttctggat cgatctgcca
    59101 gccccattca cttgcctcaa gaaacggatt ttttactcct cccagcaagt tcccttctga
    59161 agttgctgct tgtggatcag tctcattgat tgccgtagac atataataac taaatccgat
    59221 gtagtccact ggatattctt ttagcaactg gaagtctttt tccgtttgct ctaatttttc
    59281 cggatcgact ccatattttt tatgggtacg cgctgtgtat gcagggtatt ctccacgtac
    59341 ttggacatcc gtgcagaaaa aattgaattc ttggttttgg atcattgttg ctgcctgatt
    59401 gactggattg gcatcgatgc tgtaagttgt tgcatagata atcatgcagc cgatttggat
    59461 atccgaacgc aattcgtggc cgatttttac ggctttgcta cttgcaacga attgattatg
    59521 ccatgcttgg aaaatatttt ggtactctcc tgctccattg ctttttacta atccttgact
    59581 taaagctgga aagtgaaagg ccgaattgat ttcattgaaa gtcatccaat atttgacttt
    59641 actgctgtat ctctctaata ctgtctgagc aaatcgttca tagaagtcga tcagttttcg
    59701 atttttccag ccaccgtatt cttttgccaa atgaagaggc atttcgtaat gagaaatcgt
    59761 gatcacaggt tcaatatcat attttaagca ctcatcaatc agctgatcat aaaattctaa
    59821 tcccgcttcg ttaggagtac cttcgtctcc atttggaaaa attcgtgtcc aggcaatcga
    59881 aaaacgataa catttgaatc ccatttccgc aaacaaggca agatcttctt tgaaacgatc
    59941 gtaatgatcg attcctcgat gattcgggta aatatatttt tcttgatcaa tcgtccagtc
    60001 aaattcttca ctgccgataa tcgcaaagcg ctgcttacct ccaggcatag catctgcaac
    60061 ggatagtcct tttccgtctc gatcataagc cccttctaat tgatttggca gcagttgctc
    60121 caccccataa aaatttttct gaaaaacgtg attgcatcct gatttcctcc ttattttaca
    60181 attgccagaa catcttcgtt tgcaataatc tctttttggt ctaattcaag tatatcggca
    60241 aatgcatcag tattcgtaat gacaactgga gtgattacgc tatagccagc tgctctaatt
    60301 gcttcgatgt caaaacgaat caataaatct cctgctttga cgagatcccc ttgtttgact
    60361 aagatctcaa agccattccc atttaattct actgtatcca tcccgatatg aatcaaaatc
    60421 tccgctccgt cagtcgttgt gatccctaca gcatgtccag ttggaaaaat agtcgtgatc
    60481 tctccgtctg caggtgcaac tagttctcct acttctggat caatagcgat accttttccc
    60541 atcacgccag aagaaaaaac ttggtctggt acttcactca atggcagtac tttacccgtt
    60601 aaaggacttt ttaaggtatg ccgtgctgaa gtaatcggtt ctcctgcatt cgcatgtttg
    60661 ttttctaatt gattgtcttg tgtttgttcg tcaaatccta aaatcaatgt acctacgaat
    60721 gcaagaacaa aagcaattcc tgtagctatt actgctactg tcacatttga ctctacacca
    60781 tccaccgtat taatgaaagt cggaatcgtc aataagctga ccaaactgct ggagaaagct
    60841 tttactccgg aaaatccgat aatagctcca ccaatacctc cagaaataca agcggcaatg
    60901 aatggtttct tcaaaggtaa tgtcacacca tacacagttg gttcagtgat tccaaataac
    60961 gaagtcactg tagaagaaat ccctaatgct cgaagtttcg tatcttttgt tcgcaatgct
    61021 acagctaaag cagccccacc ttgtgccaag atggctggaa gaagcattgg catcaataca
    61081 tcaaacccat attgttcgat attcaaaaac atgatcggta cgaatcccca atgcatgccg
    61141 aacatcacga atacttgcca taaacttccc atgattagac ctgctacgat tggactaaat
    61201 ccataaatcg agttgaagag accgcctaaa gcattaccgg caaccgtccc gattggtcct
    61261 aaagcaagaa atgttaatgg aaccatcact actaaaacga caagcggaac taaaatcatt
    61321 tgcagaaatt gcggaatcac tttttttacg aatggctcta atttactttg aacccatacg
    61381 gctagaatga ttggtatgac agaagaagta taaccagatg gtgaaagaat cactgggatc
    61441 ccaaagaaac tgatagcttc tcccgcacca gcaactgctg tgatagctgg atacacaagt
    61501 gccatagcaa ttgctactgc taaaaactgg ttggctttga actttttagc tgctgtaaaa
    61561 gcaagcatga caggtaagaa ggtaaagaca ccatctgctg cagcaaacaa tatttgataa
    61621 gtaccgctat cagctgtcag ccagcccatc accgttgcca atgataagaa tcctttcaat
    61681 accccggcgg ctgccatcgc ccctagaaaa ggtgtaaata tactagagat aatatcgatc
    61741 agacgattca aaatattttt ggactcttct tttccatcct ccgaaactgc aagaccttcc
    61801 tcatccacga tcgattgata aacatctgct acattactgc caatcactac ttgatactga
    61861 ccgccacttt gtacgacttg gatcacgtcc gggtcttctt ttaacttttg cgtatctgct
    61921 aaagattcat cttttaatct gaatcgcaac cgcgtagcac aatgtactaa acttttgaca
    61981 ttcttttgtc ctcctaccgc ttcccataca cgacgaccaa ctgcttgatt atccattgtt
    62041 ttttccttct ttctttttta tttaaaaaat aaaaacccag attgaaaaaa acagtcacaa
    62101 acattcgtga acctattttt tcaatccagg ttttgcctgc catacagtaa caatccttat
    62161 gattggatgc tttttttctc acttactact ctttgaatat gaatcgttaa ataaatctgc
    62221 tctgcgatcc ccatttcctg tttttgcgtt tgtcgaagat actcattgat ccgttcgaca
    62281 caatgaaacg cttttggata ctttccttga actaatgcgt agagaaattc atcttgctcg
    62341 tcagatcctt cccctttgag ataacgctgg gcaaaaaact gcagatgagt aatgatacgc
    62401 tgataattca aagattcttc atcgaacacg atgccgaaga atttactgat gatactcagt
    62461 atatctctta ccattgtggt agcggtcatc gtcacttgca tgtcttcgtt tccttgttgg
    62521 ctattcacaa aatgaaaggc aataaaaccg gcttcatcct cagaaagttc cacacccgtc
    62581 ttttgtttca cgaacaaaag agcctctttc gctgcttgat attctttcgg ataaaatttt
    62641 tttgtttcaa ataataatgg attaggcagt tggatatttt cttttgctcg tgtgatcgca
    62701 taatgaagat gatcggtcaa tgtcagataa atattaggcg aaaattcaac ttttagttta
    62761 tcttcagcca gttcgactac ttgtttgacc cattcgatct cctctgccgg aatatcagcc
    62821 atcagctgct ggaattggtt tttagcaaaa gaatctctta aaacaaattc tttttggacc
    62881 gcttctggcg aaatctcgtc cccaatcttt ttttgaaaag ctagtccttt tcccatacaa
    62941 acgacttctt ccccgaatcc atttttcgaa atgacgacat tgttattcaa aattttatca
    63001 attttcattt tgcttcgccc tctcaagaaa aataaaaaaa cctagaattc gcctactgtt
    63061 tcttagctga attctggttt tgcctgccgt acagtaacaa tccatttctt attcaaaatc
    63121 atcataccat cgaattttta tttatgcaag ccttttcata taaaaaataa aaaaactgga
    63181 acacaagtct atctagaaaa
//
LOCUS       DAZKCW010000010        59069 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000010 DAZKCW010000000
VERSION     DAZKCW010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.010"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(59..187)
                     /locus_tag="ACG84Z_000701"
     CDS             complement(59..187)
                     /locus_tag="ACG84Z_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFP9161565.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACG84Z_000702"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACG84Z_000702"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFP9161566.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="ACG84Z_000703"
     CDS             complement(1674..2729)
                     /locus_tag="ACG84Z_000703"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFP9161567.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACG84Z_000704"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACG84Z_000704"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFP9161568.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACG84Z_000705"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACG84Z_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFP9161569.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACG84Z_000706"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACG84Z_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFP9161570.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACG84Z_000707"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACG84Z_000707"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFP9161571.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACG84Z_000708"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACG84Z_000708"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFP9161572.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="ACG84Z_000709"
     CDS             10491..12050
                     /locus_tag="ACG84Z_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFP9161573.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="ACG84Z_000710"
     CDS             complement(12161..14092)
                     /locus_tag="ACG84Z_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFP9161574.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACG84Z_000711"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACG84Z_000711"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFP9161575.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="ACG84Z_000712"
     CDS             complement(15021..15773)
                     /locus_tag="ACG84Z_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFP9161576.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="ACG84Z_000713"
     CDS             complement(15932..16141)
                     /locus_tag="ACG84Z_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161577.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="ACG84Z_000714"
     CDS             complement(16152..17480)
                     /locus_tag="ACG84Z_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161578.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="ACG84Z_000715"
     CDS             17616..17771
                     /locus_tag="ACG84Z_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFP9161579.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACG84Z_000716"
     CDS             complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACG84Z_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFP9161580.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACG84Z_000717"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACG84Z_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFP9161581.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACG84Z_000718"
     CDS             complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACG84Z_000718"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFP9161582.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="ACG84Z_000719"
     CDS             complement(21455..22387)
                     /locus_tag="ACG84Z_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161583.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="ACG84Z_000720"
     CDS             complement(22544..23203)
                     /locus_tag="ACG84Z_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFP9161584.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACG84Z_000721"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACG84Z_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFP9161585.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="ACG84Z_000722"
     CDS             complement(24244..24534)
                     /locus_tag="ACG84Z_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161586.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="ACG84Z_000723"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="ACG84Z_000723"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFP9161587.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERYSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACG84Z_000724"
     CDS             complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACG84Z_000724"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFP9161588.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="ACG84Z_000725"
     CDS             complement(28200..29369)
                     /locus_tag="ACG84Z_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFP9161589.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACG84Z_000726"
     CDS             complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACG84Z_000726"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFP9161590.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACG84Z_000727"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACG84Z_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFP9161591.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="ACG84Z_000728"
     CDS             34320..34841
                     /locus_tag="ACG84Z_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFP9161592.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="ACG84Z_000729"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="ACG84Z_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="ACG84Z_000730"
     CDS             complement(36284..36940)
                     /locus_tag="ACG84Z_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161593.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACG84Z_000731"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACG84Z_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFP9161594.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACG84Z_000732"
     CDS             complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACG84Z_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFP9161595.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACG84Z_000733"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACG84Z_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFP9161596.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="ACG84Z_000734"
     CDS             complement(40491..41222)
                     /locus_tag="ACG84Z_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFP9161597.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="ACG84Z_000735"
     CDS             complement(41226..42491)
                     /locus_tag="ACG84Z_000735"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFP9161598.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACG84Z_000736"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACG84Z_000736"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFP9161599.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACG84Z_000737"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACG84Z_000737"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFP9161600.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="ACG84Z_000738"
     CDS             47833..49335
                     /locus_tag="ACG84Z_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFP9161601.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="ACG84Z_000739"
     CDS             49337..50074
                     /locus_tag="ACG84Z_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFP9161602.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACG84Z_000740"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACG84Z_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFP9161603.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACG84Z_000741"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACG84Z_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFP9161604.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACG84Z_000742"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACG84Z_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFP9161605.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACG84Z_000743"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACG84Z_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFP9161606.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACG84Z_000744"
     CDS             complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACG84Z_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFP9161607.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKYGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="ACG84Z_000745"
     CDS             complement(56756..56983)
                     /locus_tag="ACG84Z_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFP9161608.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57303..57626)
                     /gene="relB"
                     /locus_tag="ACG84Z_000746"
     CDS             complement(57303..57626)
                     /gene="relB"
                     /locus_tag="ACG84Z_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFP9161609.1"
                     /translation="MRFFKRGNYRAMITVRVSDAKKEWLSYMAEFYGITLSELLKNYS
                     MEQLEDEYNRQTAEIAHKHWIRSGKTTVFMEESLMNLVGWNDLPFKIHARNSEAALIG
                     KYVYW"
     gene            complement(57969..58415)
                     /locus_tag="ACG84Z_000747"
     CDS             complement(57969..58415)
                     /locus_tag="ACG84Z_000747"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFP9161610.1"
                     /translation="MKIKIYNQEENQTRHIRNLSNAKLEEEARKVSNYNKKMAAKYVN
                     EEEFCFSKTKIYKRNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQG
                     GKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            complement(58396..58992)
                     /locus_tag="ACG84Z_000748"
     CDS             complement(58396..58992)
                     /locus_tag="ACG84Z_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HFP9161611.1"
                     /translation="MNPTLITKKELLKKLDISTGVLANLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCSKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDI"
BASE COUNT        16279 a        12803 c        10274 g        19713 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aatctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttattcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatacttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtca
//
LOCUS       DAZKCW010000011        57324 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000011 DAZKCW010000000
VERSION     DAZKCW010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.011"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(229..2121)
                     /locus_tag="ACG84Z_000749"
     CDS             complement(229..2121)
                     /locus_tag="ACG84Z_000749"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161612.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2118..3845)
                     /locus_tag="ACG84Z_000750"
     CDS             complement(2118..3845)
                     /locus_tag="ACG84Z_000750"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161613.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3861..4511)
                     /locus_tag="ACG84Z_000751"
     CDS             complement(3861..4511)
                     /locus_tag="ACG84Z_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFP9161614.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4715..5011
                     /locus_tag="ACG84Z_000752"
     CDS             4715..5011
                     /locus_tag="ACG84Z_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFP9161615.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5183..5803
                     /locus_tag="ACG84Z_000753"
     CDS             5183..5803
                     /locus_tag="ACG84Z_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFP9161616.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5895..7061)
                     /locus_tag="ACG84Z_000754"
     CDS             complement(5895..7061)
                     /locus_tag="ACG84Z_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFP9161617.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7073..7426)
                     /locus_tag="ACG84Z_000755"
     CDS             complement(7073..7426)
                     /locus_tag="ACG84Z_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFP9161618.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7554..8576
                     /locus_tag="ACG84Z_000756"
     CDS             7554..8576
                     /locus_tag="ACG84Z_000756"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFP9161619.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8595..8756
                     /locus_tag="ACG84Z_000757"
     CDS             8595..8756
                     /locus_tag="ACG84Z_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161620.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9015..9449)
                     /locus_tag="ACG84Z_000758"
     CDS             complement(9015..9449)
                     /locus_tag="ACG84Z_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161621.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9559..11418)
                     /locus_tag="ACG84Z_000759"
     CDS             complement(9559..11418)
                     /locus_tag="ACG84Z_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFP9161622.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            11419..11559
                     /locus_tag="ACG84Z_000760"
     CDS             11419..11559
                     /locus_tag="ACG84Z_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFP9161623.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(11536..12696)
                     /locus_tag="ACG84Z_000761"
     CDS             complement(11536..12696)
                     /locus_tag="ACG84Z_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFP9161624.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13003..14427)
                     /gene="araA"
                     /locus_tag="ACG84Z_000762"
     CDS             complement(13003..14427)
                     /gene="araA"
                     /locus_tag="ACG84Z_000762"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFP9161625.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14443..15141)
                     /locus_tag="ACG84Z_000763"
     CDS             complement(14443..15141)
                     /locus_tag="ACG84Z_000763"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFP9161626.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15098..16759)
                     /locus_tag="ACG84Z_000764"
     CDS             complement(15098..16759)
                     /locus_tag="ACG84Z_000764"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFP9161627.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            16977..18377
                     /locus_tag="ACG84Z_000765"
     CDS             16977..18377
                     /locus_tag="ACG84Z_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFP9161628.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18629..19708)
                     /locus_tag="ACG84Z_000766"
     CDS             complement(18629..19708)
                     /locus_tag="ACG84Z_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9161629.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19794..20753)
                     /locus_tag="ACG84Z_000767"
     CDS             complement(19794..20753)
                     /locus_tag="ACG84Z_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFP9161630.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20765..22276)
                     /locus_tag="ACG84Z_000768"
     CDS             complement(20765..22276)
                     /locus_tag="ACG84Z_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFP9161631.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22298..22861)
                     /locus_tag="ACG84Z_000769"
     CDS             complement(22298..22861)
                     /locus_tag="ACG84Z_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFP9161632.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22867..23730)
                     /locus_tag="ACG84Z_000770"
     CDS             complement(22867..23730)
                     /locus_tag="ACG84Z_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9161633.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23744..24640)
                     /locus_tag="ACG84Z_000771"
     CDS             complement(23744..24640)
                     /locus_tag="ACG84Z_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9161634.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24815..26104)
                     /locus_tag="ACG84Z_000772"
     CDS             complement(24815..26104)
                     /locus_tag="ACG84Z_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9161635.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26076..27593)
                     /locus_tag="ACG84Z_000773"
     CDS             complement(26076..27593)
                     /locus_tag="ACG84Z_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFP9161636.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27791..28681
                     /locus_tag="ACG84Z_000774"
     CDS             27791..28681
                     /locus_tag="ACG84Z_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFP9161637.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28754..29578)
                     /gene="nadE"
                     /locus_tag="ACG84Z_000775"
     CDS             complement(28754..29578)
                     /gene="nadE"
                     /locus_tag="ACG84Z_000775"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFP9161638.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29590..31062)
                     /locus_tag="ACG84Z_000776"
     CDS             complement(29590..31062)
                     /locus_tag="ACG84Z_000776"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFP9161639.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31699..32061)
                     /locus_tag="ACG84Z_000777"
     CDS             complement(31699..32061)
                     /locus_tag="ACG84Z_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFP9161640.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32284..33036
                     /locus_tag="ACG84Z_000778"
     CDS             32284..33036
                     /locus_tag="ACG84Z_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFP9161641.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33176..34099)
                     /locus_tag="ACG84Z_000779"
     CDS             complement(33176..34099)
                     /locus_tag="ACG84Z_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9161642.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34114..34386)
                     /locus_tag="ACG84Z_000780"
     CDS             complement(34114..34386)
                     /locus_tag="ACG84Z_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161643.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            complement(34856..36481)
                     /gene="groL"
                     /locus_tag="ACG84Z_000781"
     CDS             complement(34856..36481)
                     /gene="groL"
                     /locus_tag="ACG84Z_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFP9161644.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(36532..36816)
                     /gene="groES"
                     /locus_tag="ACG84Z_000782"
     CDS             complement(36532..36816)
                     /gene="groES"
                     /locus_tag="ACG84Z_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFP9161645.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            37041..37703
                     /locus_tag="ACG84Z_000783"
     CDS             37041..37703
                     /locus_tag="ACG84Z_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFP9161646.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(37779..39071)
                     /locus_tag="ACG84Z_000784"
     CDS             complement(37779..39071)
                     /locus_tag="ACG84Z_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9161647.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            39241..39870
                     /locus_tag="ACG84Z_000785"
     CDS             39241..39870
                     /locus_tag="ACG84Z_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFP9161648.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(39973..40782)
                     /locus_tag="ACG84Z_000786"
     CDS             complement(39973..40782)
                     /locus_tag="ACG84Z_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFP9161649.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(40837..41706)
                     /locus_tag="ACG84Z_000787"
     CDS             complement(40837..41706)
                     /locus_tag="ACG84Z_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFP9161650.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(41707..43023)
                     /gene="yycH"
                     /locus_tag="ACG84Z_000788"
     CDS             complement(41707..43023)
                     /gene="yycH"
                     /locus_tag="ACG84Z_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFP9161651.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(43020..44855)
                     /gene="walK"
                     /locus_tag="ACG84Z_000789"
     CDS             complement(43020..44855)
                     /gene="walK"
                     /locus_tag="ACG84Z_000789"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFP9161652.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(44860..45564)
                     /gene="yycF"
                     /locus_tag="ACG84Z_000790"
     CDS             complement(44860..45564)
                     /gene="yycF"
                     /locus_tag="ACG84Z_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFP9161653.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(45754..46614)
                     /locus_tag="ACG84Z_000791"
     CDS             complement(45754..46614)
                     /locus_tag="ACG84Z_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFP9161654.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(46601..47170)
                     /locus_tag="ACG84Z_000792"
     CDS             complement(46601..47170)
                     /locus_tag="ACG84Z_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFP9161655.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            47551..47623
                     /locus_tag="ACG84Z_000793"
     tRNA            47551..47623
                     /locus_tag="ACG84Z_000793"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47584..47586,aa:Lys,seq:ctt)
     gene            complement(48119..48505)
                     /locus_tag="ACG84Z_000794"
     CDS             complement(48119..48505)
                     /locus_tag="ACG84Z_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFP9161656.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(48502..49023)
                     /locus_tag="ACG84Z_000795"
     CDS             complement(48502..49023)
                     /locus_tag="ACG84Z_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFP9161657.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(49025..50059)
                     /gene="sppA"
                     /locus_tag="ACG84Z_000796"
     CDS             complement(49025..50059)
                     /gene="sppA"
                     /locus_tag="ACG84Z_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFP9161658.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(50092..51507)
                     /locus_tag="ACG84Z_000797"
     CDS             complement(50092..51507)
                     /locus_tag="ACG84Z_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFP9161659.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(51476..53629)
                     /locus_tag="ACG84Z_000798"
     CDS             complement(51476..53629)
                     /locus_tag="ACG84Z_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HFP9161660.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            53887..54123
                     /locus_tag="ACG84Z_000799"
     CDS             53887..54123
                     /locus_tag="ACG84Z_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HFP9161661.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            54142..54357
                     /locus_tag="ACG84Z_000800"
     CDS             54142..54357
                     /locus_tag="ACG84Z_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HFP9161662.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(55060..55812)
                     /locus_tag="ACG84Z_000801"
     CDS             complement(55060..55812)
                     /locus_tag="ACG84Z_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9161663.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(55827..57074)
                     /locus_tag="ACG84Z_000802"
     CDS             complement(55827..57074)
                     /locus_tag="ACG84Z_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFP9161664.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(57150..57296)
                     /locus_tag="ACG84Z_000803"
     CDS             complement(57150..57296)
                     /locus_tag="ACG84Z_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFP9161665.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
BASE COUNT        17041 a        11723 c         9558 g        19002 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttaagg aagaggttgt aaaatcagcg
       61 gtttgacctg agtattagag atacaaaacg gaaaaatagc ttctcatatt ttgccgtttt
      121 ttgagctaat accgaaggac agctgattga acaccgttta ttcggaaaaa gggactgtga
      181 cacgactttt gtcacagccc ctaaaaaaaa taataaattt gtactattct atgaagcttc
      241 ttcttcagaa aactgactgt tataaagatc tgcatagaat ccgtcttttt ccatcaatgt
      301 atcgtggttt cctgtttcta cgatcgaacc atgattcatc acaataatgt tgtctgcatc
      361 gcgtattgta gacaagcggt gagcaacaac gaaacttgtc cggttttcca ataggcggtt
      421 catcgctttt tgaatcagta tttctgttcg tgtatctaca ctagatgttg cttcatcaag
      481 gatcaggaca tctggatttg ctaagaatgc ccgcgcaatt gtgattagct gacgctgccc
      541 ttgcgaaata ttgcttgcat cctcgtttaa tacagtgtta tatccttctg gcaatttacg
      601 aacaaaatcg tctacgtgag cagctttagc agcctcaatg atttgttcgt ctgttgcatc
      661 gtcgttccca tatttgatat tgtcatagat acttcctgta aacagccaag tatcttgcag
      721 taccattgaa aactgtgcgc gcaattcatc acgtgaaaga tcacgggtat ctacaccatc
      781 gtaacgaata ctacctccag aaacatcgta gaaccgttca agaaggttga tcagtgtcgt
      841 cttccctgca ccagtcggac ctacaatagc gaccatctca ccaggtttga catccaagtt
      901 aaaatcagtc attagcaagt tatctggtgt gtagccgaat tgaacatttt caaaacgaac
      961 tttgtatggt gtatcttttt cttctggaag gccagatttt tcattggaca tctcttcttc
     1021 atccaacact tcaaataccc gttcggctga agcaactgtt gattggatag tgttcatcaa
     1081 acttgcaagt tgagtgattg gttgagagaa ctgtgttgta tattgcaaga acgcttgaac
     1141 atcccctaat gtcatgttcc catttgcaac ttttactccg cctagtacag cgacgaacac
     1201 atagcctaga tttttaacga aattcatcaa cggcatgatg attgccgaaa taaattgagc
     1261 tttccaacca gcggcataca gattctgatt ttctttttca aatacttcct ggtctttttc
     1321 agtatgattg aatgttttaa caatggtatg accaccatat gtttcttcta cttggttatt
     1381 caataaacct aaactttttt gctgatctgc gaaaaacact tgtgatttcg gcgctacgat
     1441 catcacgatg atcaagctta aagggatcat caataacgcg actaacgtca attgccagct
     1501 gattgaaagc atcatcacga tgaccccaat caatgtgact gcactagtta caaattgagt
     1561 caaattttgc tgcagcgtgc ttgcgatgtt atccatatca ttgattgctc gagacatgat
     1621 atccccattt gtatgtgtat cataatagga aatcggtaca cgattcattt tggcttccaa
     1681 atcatgacgt aattcataaa ctgttcgttg ggaaacacgt gtcataataa attgctgtaa
     1741 aaagttgaat acagcagaaa tcaaatacat cacgattact gtcgcaatga tctgcgcgat
     1801 tttatcaaag tctatcggaa attttgttac ttgttggcct tgttgcatct gttgagcgcc
     1861 agccattaca cctttgaata tttctgtggt tgctttcccc aagacctttg gtgtttggat
     1921 ttggaagatc acggctgcta ttgctagtac aaatacagcg atgatcgcaa ccatacgttt
     1981 agacatatag ccaaacaatc ggcgtaccgt tccccagaaa tttttaggct tttcaccttt
     2041 tacaccgaga tttctgccag gtccaccatg tcctggaccg cctgctggtc catgagaggg
     2101 acgtgtgttt gttttactca tgctaagtcc tcctctctta gttgtgaatg aacgatttct
     2161 tgataagttt cgtttgttgc taatagttct tcatgtgttc ctttgccaac cagttttcct
     2221 tcatctagca caaggatcat atctgcatcc attactgtac ttactcgttg agcaactaaa
     2281 acggtgatac tttctttcat attcgttttc aatgcttggc gaagattggc atccgttttg
     2341 aaatccaacg ctgagaagga atcatcaaac acatagatat ctgctgtttt gactaatgcc
     2401 cgtgcaattg ccagacgctg tctttgtcca ccagagaagt ttcctcctcc ttgttccaca
     2461 tggctatcta agccatcttc catctctgaa acaaaatctt tagcttgtgc gatttctaat
     2521 gctttccaaa tcatttcatc tgttgcatcc ggcttaccat actgcatatt gtctcggatc
     2581 gttccagaga acagaactgc tttttgagga acaaagccca ttaattctcg caaattatat
     2641 tgagtcatgt cactaatgtc cgttccattt atttggatcg aaccagattc gatgtcatat
     2701 aatcgaggga tcaaattgac taaggtcgtt ttacctgaac cagtcccccc tatgattgcg
     2761 acgatctcgc ccgacttggc ttggaaatca atatcttcca atgcaagttt ttctgctcca
     2821 tgatatcgat aattgacatg attgaaggcc aatgttgcgt tttttccagc aaaagaaact
     2881 gttttaggat tttcagggtc atggataccg attttttcat ccaacacttc attaatacgg
     2941 tcagctgaag cttgtgcacg aggcaccatg ataaaaatag cggaaagcat cataaagctg
     3001 atcaagatct gcatcgcata agtcataaat gcaatcagat taccgacttc caaagtcata
     3061 tctgctatgt agtgtccacc aaaccaagtg attgctacgt ttgtaccgct catgatcaat
     3121 gtcatcattg gcatcatcaa tgcgacgatc gtattaactt tgattgccgt atttgtataa
     3181 tctttattcg ctaaatcaaa acgattttct tcaaagcgtg tcttatcgaa tgctcgaatc
     3241 actctgaccc ctgtcaatcc ttctcgaaat accaggttta aacggtcagt tttcttttgc
     3301 atacttttga ataatggaac agcaaagtac atgattccgc cgatcaaaat aatcattact
     3361 gggatgacaa ctaagaagat ttttgtcaac tgatgatctt tttgataagc aagtatgctc
     3421 gcgccaatca acgtgattgg tgcattgatc atcatacgta aaaacatttg tgtaaccatt
     3481 tggatttgag tcacatcatt ggtcgttctt gtgatcaaag aggccgttcc atatttatca
     3541 aacgcatctt ttgtcagact ctctgatttt ttatagacat ccgtacgcaa ttgcttaccc
     3601 agtttctgtg attcacgagt agcaaaaaat gtatttgcga tagcagctaa gatactgatc
     3661 aaagaaaagc cgatcatcac aaaacctgta tgccaaatat aatcgacatc tccttgcgct
     3721 acccctttat caataatatt ggaggtaagt gtcggcaaat ataaatctgc cagtacttgg
     3781 atcaccatga aaactgcagc tgcaattgct gaagtcaagg agatccgttt tacgattttt
     3841 agcatctagt tcccttcttt ctatttatat actccgtttt tcagccaaga aagtttcaaa
     3901 ttgaattcac tgattgcttg ctctactgag taatcttcag atgttgaaaa taagcgatac
     3961 gaatgcgcaa ttgttgtaaa tacagtattc atcactaatt ggatcagtaa ttccaattca
     4021 tgatcatttt ttactttcag cttcgtccga tcgatcaatt caagcaactc ttttgcatct
     4081 tgtttgtgtt ctttatgtgg atcgtgaggc gttttttggc gactcgtatg aggagcgact
     4141 tttcttgagg cacggtaatc catgttcata aacaagttac gataaaaaga agcattctcg
     4201 ccttccaaaa tctcataaat cattttagaa aaataggatt cgaatccttt gaatagatca
     4261 ccatcggatt ctttcattag ttgtaacata tctttagagc tgtcacgtct cattgtctca
     4321 aagtaataaa aataaagatc ctctttatct tcaaaatact gatagaaact gcctctaggg
     4381 atatccgcta atttgacgat attagcaatc gaagcttctt ttaagggtac tctagaaaac
     4441 tcgattctcg cagcctcgat tagtcttttt tgtttttctt taggcaaatg gaaaaatgtc
     4501 tgtgtcggca tatggatcct cctttctttc aagatgacac attgtcatat gacgctgtgt
     4561 cattataaca cctcctacct gttttgcaag acatttgcat agtttttttc attatcatcc
     4621 gatacattaa aaaagtgata agaggaatcc ttccatttga attaatgaga gttgcccatt
     4681 aaaatagcca catactaaac aaaggatgag ataaatggcc caatcaatta gtgtccaaga
     4741 cttcaataaa ttgcctctcg atgctgacag catcgtttta gatacaagaa ataccttaga
     4801 ttacacaaaa aaccacttaa gccactcgct ttctatcccc gctgctatct tgccaagaca
     4861 attaaaaaat ctagatccaa agaaacttta ttatattcta agctatacag gcaggcgatc
     4921 agaagcatta gccgatcaac ttactgctaa tggttttcgt gctgtttata tcattggtgg
     4981 gatggaagct cttcagtcga gtgttgcttg aatattgctt gttagattca aaagaggctg
     5041 tgacaaaaaa tcgtgtcaca gcctctttta taccctgtct ttttttagtt atttattctt
     5101 caaccttatc aatatgactt gatagccttt tctttttctc atagttataa caatcatagc
     5161 aataaaagga gaaggtaagc atatggcatc tgttttagta gtcaaaggtc atcccctaac
     5221 tgcagaagaa tcgcgcacag ttaaggcatt gacgtctttt ttaacaagtt ataaagaaaa
     5281 tcatccagat gatgaagtga ctgttttgga actttatcgc gatgatattc cggaaatcga
     5341 tgaagaatta ttatcaggtt gggaagcatt acgtgctggt gcagaattca cttccttatc
     5401 agaaagtcaa caacaaaaaa ttgctcgttt caatgaattg actgatcagt tccttgctgc
     5461 tgataaaatc gttatcgcaa acgccttatg gaatctaaat atcccaacaa aattaaaagc
     5521 ttggttcgat accgtcaatg tagctggaaa aacgttccgc tatacagaaa acgggccaga
     5581 aggattagtg acaggtaaaa aagcactgca catccaatct aatggcggtg tatacaacgg
     5641 acaagacttt gcctctcaat atgtaaaagg tattttaaac tttgtaggca tcgatcaagt
     5701 agatcagcta ttcatcgaag gaatcgatta tgaccctgac cgtgcagatg agttgatgca
     5761 aaatgcatta gataaagctg ctgctttagg taaatcattt taaaaattga gataaatgca
     5821 tacaaaagag acagaggaaa aaatcttcaa agcagcattt gtaccttgga tattttccca
     5881 tctgtctctt tttgttattc tttctgcttt ttcaacggat tttcttcata aagagaagag
     5941 attgttgtgt accattcaaa aacatgagta atcactactt tagctgctgc ataaacagga
     6001 atccccaaga tcacaccgat gattccgaac aatttcccag aagtcagcag aactaataaa
     6061 atcgttactg gatggattgc taactgattc cctagtacta atggagagat caagcgtcct
     6121 tctattgtct gctctactgc aaaaacgatc agtactttga tgatcatgaa tggacctgct
     6181 acaatggcta aaaagatagc cggaatcatc gctaaaaatg atcctaagta agggatcagg
     6241 ttcaaaaaac ccgcaataat ccccaacgtg acagcatact ctaaaccaat gaccgcaaaa
     6301 ccaatcataa acatgattgc cacagcaaaa gccacagtta gttgtcctct tatataagaa
     6361 gaaacttgac tattcatttc actcagcaca ttcaacgtcg gtttttgcat gcgtgtcggt
     6421 aaaaatttga caaaataagg tgctaattgt ttaccgtctt tcaatagata aaataagata
     6481 aacggcatcg tcagcagagc cactaaaata gtcgctaccg cgccgacaaa acttccaaga
     6541 ctctgaactg tactcttaga tatatcttgg atcatatcgc ctgccgaatt catgaactta
     6601 tcacctgctg tttccaactg ttcgcgaaat tggttgaaca gcgggtcccg caaaatctcg
     6661 gttaatttat tatcaatcgt atctacatat tgagggaagt tactgatgaa gctcactgtt
     6721 tgttcctgaa tcttagggat gatcactacg ctcccccatg cgattagtgc aacaaccaaa
     6781 acaaacagcc caatgatact gtaaagcctt ggtacttttc gcttttcaaa gtaatcaact
     6841 accggattca tcaagtaata caagattcct gctaaaatga taggcagacc tacgattgct
     6901 aaaaattgcc agattggtgc aaacaaatat gaaacttttg taaataaaaa gacgatcagc
     6961 aatattaaca atacaacaag taaggctgtg actacttgat tatttaaaaa ccagcgccaa
     7021 aaccacgata ccggtctgtt cttcttattt tttccttcca taattcctcc tgttagttat
     7081 aaaaaatttg gcttcccaaa ccaatagcag gcagtctatg cggatgaaga tagattccat
     7141 ttgcaatttg tccttcttct ggacaagcat caaaaatcaa tgatacgtga gctactgtct
     7201 ctaaattccc attggccatc ggaccgacat aatcgatcgt atatacctga tcatcaaaag
     7261 caattgttcc gcctgctttc aaagaaaaag gttcgtcttt tgatacttct tgaatcaccg
     7321 aatattttcg taaggcagct gttgctgttt tatcgaacaa aatcagcatg ggttcttcct
     7381 tgtttattgc ttctgtccca atttctgtaa tctttgcctg aatcattgca ctctctcctt
     7441 taattgcttt caaaaacagt ataacacatt ctcattcttt agccgtgtgg aataattatg
     7501 tgatagaata aaaacgaaaa ctatttcatt acaattagga ggaatcagct catatgatcg
     7561 aaaagataat tttaggaacc tatacgcgtc gcgaaagtaa aggaatctat acgatcgacc
     7621 ttgatacaga aaaagaagaa ttagccaacc tttcattagc tgttgaagaa aatagcccta
     7681 cctatgtagc aaaaagtaaa gctggcaatc tttacacagt tactagtgtg gatggattag
     7741 gtggtgccgg tgcgtacgat aaggattttc attttttgaa tgcggtaaca gagtctggcg
     7801 ctcctttgtg ttatgtagcg gttgatgaag cacgtcaatt actatacggg gcgaactatc
     7861 ataaaggtga agtaaatgtc taccatatat taggagatgg cgaactgaaa gcagcagatt
     7921 caatattcca tcaagaagcg acaggtcctc ataaaaacca agatcatgcg catgtccact
     7981 atacggatct gactcctgac caacgattag tcgtatgtga tcttggtaca gatcgtgtgt
     8041 atacttatga tgtgtccgaa aacggcaaat tgaatcttgt aactaccttc actgcagagc
     8101 caggaacagg ccctcgccat cttgtctttc atccaaatgg acaattcgct tatttatttg
     8161 gtgaattaga cagcacagtc cgcgtgcttt cttataataa agaaacaggt gcttttgaag
     8221 aattacagaa aatatcgacc ttgccagaag aattcgacgg tgaaaatgga ggggcagcta
     8281 tccgcatttc aaatgatggc aagttccttt atgcttctaa ccgaggacat aactcgattg
     8341 ctgtattcgc agtttttgaa gatggttccc acattcaaaa caagcaaatc atctcaacag
     8401 aaggggattt tccccgcgat ttcgcactag atccaagcaa taattttgtc gtgtgtgcca
     8461 atcagaacac cgataatctg acattatatc gccgtcatcc tgaaacagga ttactggaat
     8521 tactgaaaaa agatgtctat gtaccagaat gtgtctgtgt ttattttgat cgttagtaag
     8581 aaaaggagaa tgaaatgaat cagcaagacg tattagacag actacgggaa gaactaaata
     8641 ttcctttctt tgatgggaaa atcgaagata aagagtatag cgaagaggaa tatcagaaac
     8701 tcaaagccga tttacagaac tactttgaac aatatgtaca gaatgtagaa aactaatcag
     8761 ctttccatac tatctgaaaa gaacatcagg acaagacttt tccgtctatc ctgatgttct
     8821 tttctacaaa taaaaaaccg ccgagatggt tagactcgac ggaaaaggag tatttactcg
     8881 attttgagta agtacaaggt tgttgttggt tataggtatg tcattatcat aaaggatttt
     8941 gatcactcta tcataaaggt aatattacat ttatattaga taactctagt ttttattgtt
     9001 atcaaagatt tcttttattt tttcaacaac aaattagtca ttttttggat ggcagctgtc
     9061 aattggtctg tcgcttggtc ttgttttgct tcagatgtat tgaatagatc ttcatctacc
     9121 cctgattcaa gatcgatact ttggatcatt tcttcacagc ctgctacata tgaaagataa
     9181 gctttttcaa aatttttatg aatgcccatt gcttttgctg gtggacgcaa agtactgact
     9241 ttcttaagca ttgcccgata tttttttgtt ccttcttcaa ataacaggat gatctcttca
     9301 agagtcgatt tgtccagttc acttgttttt ccttcatcaa ttgcgtttct gatcacttca
     9361 tatttcggat gcattccttc tccgattgct tctgtttcct tgacgatttg atcgatggac
     9421 tgcacataat agccaatatt cggtaacatg ttcgttttcc tactttctcc attgttgtta
     9481 ttatttattc tacttgtttt tatcctcaaa tgacaagtac ttgaaaaaat ttaatggttt
     9541 ctatacagct cgccattctt attcgtgctc aaagaaacca tctgctaaac tatattgttt
     9601 ccctgcgaca atgtcatatt ggatcaattg atattcgtcg taaatctctt gttgcgagcg
     9661 attgaattgc gcttctttat accactgtcc gttttgatag tacagttctc gttcaaacgc
     9721 cggaagttcc tgttctaatg ataaaagcag ctgataaaag ccatttgttg tctgattcgt
     9781 ctgttccatt agattcgctg caaaataaaa cggactggtg attgcatcgt gagtcgtttg
     9841 cttttctaat tctcctttac tgtcgaacat aagaaattgt gtttcatgca atgtttgttt
     9901 gtcatttttt gcttggatcg tatctgaata gatccctgga agatgatccc cccaaaaaac
     9961 aactaaagtc cttctagaaa gattcttcaa ttcttccgtg aactgcttca gtgccgtgct
    10021 gctataggaa atatcttgca gataattctc taagtcaagt gtcccacttc catctgaagt
    10081 ttttgcagga tagtctagat tatcatactt tccatcgtag ggcatatgtg tctgcatcgt
    10141 gactaaatga atgaactgag gtgttttttc ttccttgaga agtgtcatta cttctttgta
    10201 agctgactca tcagaaatat atggattatt ctctatcgta tccgtatagg tcatcgtacg
    10261 ctcgctgatg aactggtcaa atcctaatgt ctgataaaca tcctctcttt tatacatcga
    10321 agtattgtat ggatggatcg ctgtcgtctg gtatgattgt gcgtttaacg ctgaaacgat
    10381 agaaggaagc tgatccattt ttggtacaag catcgtgtaa ggggtggtga gttgcgcatt
    10441 aaataacgcc atagaaaaac cagtcaatgc ttcaaattcg atatttgctg ttccaccgcc
    10501 atagttttga gaaagcatat tgccactata tgtttgatca gctacttcat aataatctgc
    10561 caatggctca ccagatactt ctacgccgtt taatcgacta ggatctgaga aactttcact
    10621 catcacgaac acgatgttcg gcgactcttc ctctacagtt ttattttttt catcggctag
    10681 cttctggtat ttttcagtga tttctttgat cttttctttc gaatatcctt caggttcatc
    10741 cattggttct accttcagat tgtacaaaaa cccaccgata aaaccagtgt tatagtagtt
    10801 cattttctgg ctgtaaggta tccatagtgc cgttttatta tatgcttttc gcaacaaatt
    10861 atcgggattg ttgaaattac tgatataccc tagcagtcca attgccacaa gcagtgtcgt
    10921 taatcggatc aattggaatc gccttccttt tttcaggctt cgaaacatgt accagcaaaa
    10981 caatcctatc acggttcctg cggcagctaa gatcactgta aacagcatag tgccggtcat
    11041 atctttcagc aatccgattt cagtgatcat cttcaaatcg tctggataaa tcggttcttg
    11101 ccgataactc attttcatat aatttgcaaa acctaataca ccgatggcta cgacatacgt
    11161 aagggaacct aaagggacag atcctgctag tgcaatcaga aaaataagaa taatcagcaa
    11221 gacgagacag gctaagaaga atttttccgt atgccaagaa aaagcaaatt tcaacgcaag
    11281 gtctacggat agatcatttt gacaccactg caaaaataaa ttactaaaaa caacaagaaa
    11341 aaagatactg atgattgctg ctgttccttt taaaatcttt ttctgtttgg tcgaaagtct
    11401 gcttatatat cttttcaaat gcttgctcct tcatttctat caataaaaga atgttgcttc
    11461 tcttatttta gttgtacgaa attcgaaagt aaagaacgga aagaagaatt aatgaaatcc
    11521 aaatattctc tttctttatg gcctttctgg tttctttaat aagcggacct ttcgtactcc
    11581 agaaattttt tctagctgtt gtttcacttg attgagctgt tcaaaatcag tactgtctat
    11641 gtcaatcaat atgtagacat gctcattctt atggttacgc gatatatctg cgatcgctag
    11701 ctcgttctca ttcagcagag aaaatatctc tgctaatata ttggttttct tttgataaaa
    11761 tatagtgaat cgaaacggcg cttggaaaaa cattcgtgcg gatggataat tgaccgcttc
    11821 tctaaccgta ccgaacaaaa gataatcttt taaggcttca actgccaaac gtccgctgtc
    11881 tgccaaagct tcctgagtcg atccccctag atgaggcaac ataagtatac ggtcattttc
    11941 taagaactct tcttctggaa aatcagtcaa gtatttagcc agatgttgtt tttccaatgc
    12001 ttgcataaca gcatatttat caacaatttc acttcttcct acattgataa gtacagcatc
    12061 ttttttcatt ttttctatat tcgcctgatc gatcaatcct tttgtatctt ctgtcaacgg
    12121 cagcatgact acgatgtaat ccgaggtaga aagaactgtt tctaaatctg cttgccgaac
    12181 ataatccaac tgggcatcgc ggatagaata acccaagaca tccatcccta agctatagca
    12241 acttagcgct acttttgtgc ctatcgctcc aagaccaaga agaccgatgg ttttgccttg
    12301 caattctcgt cccacataag cacttctttt gttttctgcc tgttctaaaa tattaggacc
    12361 tgttagtgtt tgtaccatac gacttgcttc gattatcgga cgggaagata agagcaaaca
    12421 gcacaaaaca agctctttta ctgcattagc atttacacct ggtgtattca tgacgatcgt
    12481 cccgttttca gaagcttttt caacgttgat cgtgttcacc ccaacaccag ctcttgaaat
    12541 tgctagcaaa tctggtgtaa gccattcatc tttcactttc gtactacgaa taactattcc
    12601 ttcggctggc aaatcatcta ttattttgaa atattcccct tgtaactttt ctatctcttg
    12661 ttctggaata gcatcaatca aatgaacgtg atacataaaa ccccctcctt actaacaagt
    12721 atctcgaaat ttctgcaatt agacaactgt ttaccatttg acttcctaga agcaaaaaga
    12781 gcagttagag cagagtaggc tgagtgataa aaataaggct atgacaagtt actgccataa
    12841 gccttatttt cgagagcaaa atattgaggg tgagatatct tgataaatgg tgttccgtta
    12901 gctgacattg ataataagac taaatttcaa aaaagttgaa aagcaaattt cgtcaatctc
    12961 ttcttatttc ttaaaactaa gtggcttttt cacaacctct ttttatctaa taaccactgt
    13021 ttccaactca actaattttg cccacgtttc aatttgatct gttgttagat ttagcgagac
    13081 aacggtatga tgaccgccac ctgcctgaat ccatgaatgg acaccttcat ggaaattcgg
    13141 tttagttttc cataacacac gtgcaacagg taaattaggt gcttcagtcg ttggttcaaa
    13201 ggcttctact tcattgatca gcagtttata atgcgtaccg aaatctgcca tcgatacgac
    13261 taccccttct cctgctttcc catcaaatac aagacgcgcc ggatcttctc tatctcccat
    13321 tgataaagga gaaacaacga ttcttggttt cgtcgcagca agcgtcggat ctacttccat
    13381 catatgggat tccaagattg cttcttggcc actagctagc tcgtaagtat aatcttccat
    13441 gaatcctgta tctttccctc gagccatgat tttcagcaac cgatcaatcg ctgcagtttt
    13501 ccagtcgcct tccccagcaa aaccgtatcc ttctgccatc aaacgttgta cagctagtcc
    13561 aggtagttgt ttcattccat acaggtcttc aaaattagtc gtaaaagcgt tatagcctcc
    13621 ttcttctaag aaacggcgaa taccgatttc ctgctgagct tgtactttta catgttcctc
    13681 ccatgtcttt tcttcataat caccatagtc gaaggtatac aattccttgt actcttcaaa
    13741 taattgatcg acttcttcgt ctgatacgcg atcgattact tgtacaagat ctccgatacc
    13801 aaaataatca acagtccaac caaattgaat ctgtgcttcc actttgtctc cttctgtgac
    13861 acccacgttt ctcatgttgt caccaaaacg agccactttt attccaaaac tttcattata
    13921 ggctactgca acatccatcc aatcagcaat ctctttttgg atctcaggtc gtttccagta
    13981 gccaacgacg attttatttt gtttatttaa tcgagcattg atgaacccat attcgcggtc
    14041 accatgagcg gattgattta aattcatgaa atccatatcg atcgttttcc aaggaatgct
    14101 ttcgttatat tgcgtagcta aatgaagcaa tggtttttgt agaagctttg tcccgcggat
    14161 ccacattttt gctggtgaga aagtatgcat ccaagtgatc acacctgcta cttcttctcg
    14221 ataattgacc tctttcatga tttttgtgat cgtatcagca gtaactgcta attcttgaag
    14281 gcggattgga taaggcaatt ggccattttc attcagttca tcgaccattt cttgtgcatg
    14341 tttctttact tctcgcagtg cttcttcccc atataaatgc tgtgatccta caacaaacca
    14401 aaattctttt tctccaatat tcaacataat tagccactcc ttttatttgt tttgtccgta
    14461 atacgcattt tttccgtgtt ttcgtaaata atgtttatct aaaatccgtt gaggcagctc
    14521 ttctgaaaat gaattgagct gtctggtaaa taaattcatc ttgcatactt catctagtac
    14581 gactgcgttc attaccgcac tttgcgcatc tttcccccaa gtaaatggac cgtgtccgtg
    14641 taaaagtacc cctggaattg ctaagggatc aattttgcgt tctttgaatg tttctatgat
    14701 aacttttcct gtttcatatt cgtacccgct gtcgatttcc tgttgtgtca aaaatcgagc
    14761 acaaggtacc gatccataaa aagtatctgc atgcgtcgtc cccatcgcag gaacatccaa
    14821 tcctgcttgt gcccagatcg tcgcccatgt cgagtgagta tggacgattc ctccgatttg
    14881 aggaaatgaa cgatataaaa cagcatgagt aggcgtatcc gaagagggat tgagtttacc
    14941 ttcaatgata tgattgtcca agtccacaac gaccatgtcg tctgctgtca tctcttcata
    15001 actgactccg ctaggtttga taacgaaata tcgtgtttca ggatcaaaag cgctcacatt
    15061 tccccatgta tatttgacga gtccgtgttt aggcaagtca agatttgctt ggtatacttc
    15121 ttctttcagt tgttccagca ttttctatca ctcctttttc ttgcaattga tgaatcgctg
    15181 ttttttcaat gtcgatcccc tcacggtaac gtctcataaa tatctgatag cctgctattt
    15241 cttctgctga aggtgtgatg gtgattcctt ggtcttgtcc aaacacgtct tctgccaaga
    15301 agttttctaa agacttccca tgtcgatcca tcatataggc tgctaataac gcgattcccc
    15361 acgctccacc ttctccggct gtgtccatca ctgtaactgg tgcctccata gcagatgcta
    15421 gaatccgctg tccaacttct ggtgttttaa aaatcccccc atgccccact aaacgatcaa
    15481 tttggacatt ctcagatttc aatatatcca ttccgattct cattgcacca aaagcactgg
    15541 ctaaatggat ccgcatgaaa ttcgctaaat caaaacggct acctggtgta cgtacaaata
    15601 atggccttcc ttcatttact cctgtaatgt tttcaccgga aaaataacca taagaaagta
    15661 atcccccgca atccgtatcg ccttctagcg ctttgttgaa taataccgtg aataatttat
    15721 ctctgcttat ctccataccc aaagaattgg taaattcttc aaaaatactg acccaagcat
    15781 tgatatccga agagcagtta ttcgtatgaa ccatgcctac tagttctcct gaaggtgtag
    15841 tgaccatgtc gatttccgga tggacatttt ctagttcttt ttctaatacg atcatagcga
    15901 aggcggaagt accagccgaa atgttccctg tccgtttggc tacactgttc gtagcgacca
    15961 taccggttcc tgcatcccct tctggcggac aaaccgggat tcctggtctc aaatttcccg
    16021 tagggtcgat cagataagcc cctgattcgc ttaacttgcc agcttcttct cctgctacta
    16081 gaactttagg caaaatgtga tccaagtcaa tcgctacgtg cgctttttcg attaactgac
    16141 caaaaatatt tttcatttct tgatggtagg ttttcgttga aggatcgata ggaaacatgc
    16201 ctgatgcatc tcctacgcct agtactttct caccagtaag ctgccaatgg acataacctg
    16261 caagcgttgt caaaaaatta atttctttca catgttcttc tttattcaaa atagattgat
    16321 acaaatgagc gatactccat ctctgcggaa tattgtattg aaatttttcc gttaatattc
    16381 gttctgcttc ttcagtgatt gtatttcgcc aagtacgaaa tggtactagt aactgttcct
    16441 tgctatcaaa tgctagataa ccgtgcatca ttgcactgaa cccaatcgac ccgattgtcg
    16501 taagattctc gccatagatt tcgaatactt ctgctgccat ttttcggtaa ctgacgcgca
    16561 gtcctttcca aatatcttct aatgaatagg tccagatacc attttctagt ttgttttccc
    16621 actcataact accagcggca ataggagtaa aagatgaatc aatcaataca gctttgatcc
    16681 tagttgatcc aaactcaatc cctaaagatg tacgaccatc tatgacatct aacatacttt
    16741 gcgcatttac ttccttcata atgatttaac tccctccttc tcgtcaaacc tgatcaaacc
    16801 gtctttttag tagcgcttac aatgattatt gtatactttt gtacgtacat gtcaagcggt
    16861 tatttacaag aatacaataa aaaacacttg ttttgtacgt acataagtta taaaatgaaa
    16921 ttgcttacaa aatctgatca accgccttct cgaaattcta gaaggagaga atacttatga
    16981 aaaaagaaaa aaaagtttcc tcatcgttta tttatttttt tggcgcattt ggcggcattc
    17041 tatttggata tgatattggt gttatgaccg gcgccttacc ttttttacag catgattggg
    17101 gtttggcagg taaagcttct ttgataggat ggatcacgtc ttcggtcatg ttaggtgcga
    17161 tccttggcgg ctctttatct ggtcttcttt ctgataagct tggacgacga aaaatgattc
    17221 ttctttctgc acttattttt atggctggtt ctgtcctttc tgcatctgcc cctcacaatg
    17281 gttcttattt tctgattgca gcaaggattc ttctaggttt agctgttggc gctgcatctg
    17341 ccctagttcc tgcttatatg tctgaaatgg ctcctgctag actaagggga agattgtcag
    17401 ggatcaatca agtgatgatt gcttctggca tgctcctttc ctatgttgca gattatttgc
    17461 taaaagtgtt gcctgaaacg atggcttggc gcgtgatgtt agggctcgct gctgtccccg
    17521 cgctgatttt atttttcggt gttttagctc taccagagtc accgcgtttt cttatgcaat
    17581 ctggccgctt ggaagaggca aaaagagtat tgaactatat tcggacacca aaagaagctg
    17641 aacaggaatt cgaacaaatc cagctgaatg tcaaacaaga aaagacaacc ggaacttctt
    17701 ggcatacttt gtttttagaa aaatatcgtt ccttagtcat tgccggtatt ggtgtagcag
    17761 tattccagca atttcaagga gctaatgcta ttttttacta tattccgctg atcgtagaaa
    17821 aagcgactgg gcatgcagcg agcgatgcat tgatgtggcc gatcatccaa ggaatcattt
    17881 tagttgctgg ttctttgctc tttttggtta ttgcagacaa gttcaatcgg cgaactttat
    17941 tgaaaatagg cggtagcgtg atgggacttt cattcatcct accagctgtt ttaggaactg
    18001 tactggatgc tcatacaaat tcgttgttga ttctcttgtt tttatgtatt tatgtcgcat
    18061 tttattcttg cacatgggct ccactgacat gggtaatcat aggcgaaata ttcccactag
    18121 ctgtccgcgg gcgagcatct ggcctagcct cttcttttaa ttggattggt tctttcctag
    18181 ttggcttgct ttttcctgtg atgactgctt ctatgtctca agaaatcgtt ttcggcattt
    18241 ttgggatcat ctgcttttta ggggttttat ttattcaaga gatcgtacca gaaactcgtg
    18301 ggaaatcttt agaggaaatc gaacaaagtg catctaaaaa aacttatcct aaacgtattt
    18361 ctatccatca ttcttaaaga ggttgtgaca gaagtggtca gcttcaagaa ataagaagga
    18421 accgcttagt ttccagtcac aaggaacaat ttcaaaaaac agcttctcat gtttgatgaa
    18481 tattgtgact tgtgaccagt tggtaggaga acaccgttta gtggagaggt ggtgaaagaa
    18541 acgttcagcc ttgagcgatg acaaaagctc tcacaaacat tgcgacgagt aaccgtagga
    18601 gcaataagag gcggtaaaaa cccgtctctt atttttcgtt ttctttcact gtttcccgtt
    18661 caactagtac aggttcatag agaatatttg gctgtgcctg tcctttttca atcgttgtga
    18721 cgatccaccg tgcggcatct tgtcccaact tttcttttgg atgcgtcaat gttgtcaatt
    18781 ttttattccc taaatggctt aaagaagaat cgtctgttcc tacgatcgat aggtcatctg
    18841 gaatatgata gccattttct gtcaacttat ctagcattaa actagctatt tgatcgttat
    18901 agcaaatgat gccatctaaa gcttgttctt ctttcaaccg ttgtactgtt ttttcagcga
    18961 ttgtttctcg tgtttccgtg gtgaaagtaa tgatatcttc cgtcaaaaaa cgcacattat
    19021 actgttcaca cgcgctgata aaacctttca tcctgtattt tccttgaaga tcgtcgattt
    19081 ttgtgatgaa caacagacgc tgatgtcctt tttttatcaa atattctgct gccataaaac
    19141 cgactttcac atcatctaaa caaatataag aggcatttaa ctcttcataa gcagcattga
    19201 tcatcaccat cggaatgcct tgttctctca aagcaacata aagtgctaag tttgggttat
    19261 actgattact tttcgtaggc tcaacgatca aaccatctac cccataagca atcattttct
    19321 tcaaacactc tttctccaat tcgtgatcgt tattcgtact ggctaaaagc aatgaatacc
    19381 cagattctcg taattcattt tcgattcctc ggataatcga cggaaaaata taatcagaga
    19441 gatatgtggt gatgacaccg atcgtttttg ttctgttcaa tggtgttttt tctttcttat
    19501 agctgtcatc tacatatgtg cccgaccctt tttctttacg cagatagccc tcatttacca
    19561 acacagcgat tgcttgccga atcgtatgtc tgctgacgtc atatatttct tgcagcttga
    19621 attctgaggg aatggttgta tttacttcgt attcctcacg aaggatcttt tgttttatct
    19681 cttctgcaat atcttgatat tttgccattt gccttgcccc tttttatttg tacgtacata
    19741 tatcataacg agtctgcaag gtttattcaa gcaaaaatca aggtttcttg tgctcataag
    19801 gcatacggaa caggttcacc aaattctgga aatccttgct cattccacgt aaagcattgc
    19861 gcgttcgcgt gccgattagg attgtctaac ggatcccctt tttggttctt ctctggtcga
    19921 gcatgataga tcaaaatatc aaagcacccg tcttctgaaa ccgtaaacga gttgtgacca
    19981 ggaccaaatt gcttattttt ttcagaagaa acgaatactg gctccgataa tttatgccat
    20041 gattctttta ataaaagatt cttgtgctca tcagcccaca gcaggcccat ggcatagttt
    20101 tcatctgttg cactaccaga atacgtaatg aatattttcc cattgcgagt aaggactgct
    20161 ggaccttcat ttactgaaaa accccgtttt tcccattcat actcaggtat agaaaggagg
    20221 atctgcttcc cctttaacgt ccaaggatta tccatttcgg atagataaag attagaattc
    20281 ccagtaattt caggatcttg ttgggcccac acataatata gctttccttg agaagagaaa
    20341 gttgttccgt ctaaactgaa agtttccctt ttcgttttta tttgtccctt ttctatccaa
    20401 tctgtattca ttggatctat atgctgattt tcaagtacga acatgcggtg atgatgagat
    20461 tcatcacgta tagttttatg attgcttgca gcaaagtaaa tataccattt tccattgata
    20521 taatggactt caggtgccca gatcaattca ctcatcggtc cttcttcatg agcctgccat
    20581 acaatcaggc ttgcagcatg ttctaattca ttcagtgact ttgcccttct taattcaatc
    20641 acttggtagc ctggaaccga tcctgtaaaa taataataac catctgtatg tttatatacc
    20701 caaggatctg cccgttgccg aacgatagga ttattataaa gtgtcttcat cataacaaat
    20761 ttcctcacat tttctttatt ctaattacat tccaagagta tttttctatc cctacattta
    20821 attcgtcatg tttttctatt gaaaaatagt ttatttcagg ttttattttt tctggttctt
    20881 cacgtgtatt tttgtccaac agatcgctac tggttaatgt gtagtgctct ccttgatcta
    20941 gcaaattgaa atcatgttca atcgttatct tttgttgttc atttgtgcga ttgatcaaga
    21001 aaatagtcag ctgattgccg ttatctacga tcacactgtc cacataagga acatttttta
    21061 tcttttcaca atcataaaca gggcaaatga tttgttgttt caatacttga cctttagcat
    21121 atttcgataa gtgttgcatc acataataag ttggattcct ccatgcttgt cctttagcat
    21181 ctgtcagtat taaaggtatt gtgtttacta acaatgattg acaactaatc tttacgcgat
    21241 ctgcgtgtcg taaaatagcc agccctaatg aaccaaataa taatgtatct tccatagtaa
    21301 agtaacacca atcgatggga ctaccgactt caaaatccct atgtcttttt tccggttggg
    21361 catgtacatt ccattcatca aacgctagat acattgtttt ctcacttctc aaatatcctt
    21421 ttacataatc acaagtagca acgatttctt caatttgacg atcgaatcga taagcttttg
    21481 caaggtatgt cgctgtatca tcacgctcat ttttaggagg tttagtcaag tcttcttcat
    21541 catacttatc aatatagtta tgcaaagcta aataatctac attctcataa gcttcttcta
    21601 atgcgatacg atcccattca gggtacgatg gtaaacgtgg cgtagagctt ccaactaaga
    21661 ttgtttcaat tgaatcatcc actaacttca tgacttttga ggcttcattt gctaacctac
    21721 catattcata agcactctta gcccccactt gccatggacc gtctagctca ttccctaaac
    21781 accataattt aacgccaaaa ggcttttttt gcccattttt tattcttaaa tcactccaga
    21841 aggttccttt tggaaaatta caatattcta ctaaattttt tgcttcatca attccttttg
    21901 ttcctaaatt caccgtgaat atcggtttcg cttgtacatg actgatccat ttaaaaaatt
    21961 cgtggagtcc aaaagaattt ggttctatac ctcgccatgc taaatcaatt ttttttggtc
    22021 gttgttcttt cctacctaca gtatccaccc aatcataacc agatgtaaag tttcctccag
    22081 gatagcgaat gacacctaat tctaattcct ttacataaga gaggacatct tgtctaaacc
    22141 cgtcaccatc agctgtttca tggcccggtt cataaatccc tgtatagacg acacttccca
    22201 tatgctcaac aaatgagcca aacagccgag aactgatctc tcctaccgta aaatcctctc
    22261 tgatttttac tttcacttct tcgtccaaca gctttcccta cctttcattt cctatagtca
    22321 agataataga tacaagtttc catacgccac cagcaaagat aaaaataaaa ggagggaaaa
    22381 gaaatatgag cagtacaaat cctaataaca atacgcaaca aagaatattt ctcaaaaaat
    22441 caaaaaatac tttccatgca ctttgttcaa aaatttgtaa aaatgtgata tctttgtttt
    22501 cagaaatcac atatatccag gataaaagaa acatggaata aataagtaaa actacatatc
    22561 cactaattga aagtacgatt gtctgttctt ctaataattg attaacaaga aaataaataa
    22621 tgatcgttaa cagactaagg aacaagttct taccaaaatg ttgctttatt ccttgaaaga
    22681 aaaaataaat gatatttcct gatccctcac ctttccattg cgccattaca taaaaaacag
    22741 cacatgtagc aggcacgata gtaataacag gcaaacacac gattacccag agaataccta
    22801 ataagatgta atcagaaacc acaatcaact gtccataaaa tttagtctca actattttca
    22861 tcttcctcac tctttcattc cagacatagc tgttccttga acaaaatatt tctgtgcaaa
    22921 aatataaacc actagtaatg gcagcattga aataaccgtt ccagccatta caggtccata
    22981 aaaagaaatg ttctgccctg taaataaagc taaccctgct ggtaaagttc tcatttttga
    23041 actacttgtc aatatcaatg gataaagcaa gtcattccaa ctattcatca gcgtgaaaat
    23101 ccctaatgat aaaagagtag gtttgctcaa tggcaacatg attttcaaaa aaatattaaa
    23161 ctcacttaat ccatcaatgc gtgctgcctc ttccaaagaa tctggtaaag taataaaaaa
    23221 ggaacgcatc atgaagatac caaatgcagt tgtcatacga ggaatgatca aacctgcata
    23281 agtatcaagc atgccaagca aattgacttc aataaataga ggaatcatga agacttggaa
    23341 tgggatcatc attgtcagca aaacgaaata gaacaaaact gattttcctt tgaaacgcat
    23401 acgagcaaat gcataccccg caagagaatc aaagaataca gaagtgatca ctgtccctcc
    23461 agcaaaaatc actgtatttt tgatgtaatc taataaaggg atcgttgtcc aaaccttaat
    23521 atagttatct agggtatagc tatctgcaaa tattctaggc ggaaatgaga taatgtcttt
    23581 ttcgtgttta aaagaagaaa taatcagcca caaaaaagga aacgcaataa ccaacaatat
    23641 aactagcata ctaatcgttc gaatgatttt tttaccacta actgcttttc gactattcac
    23701 agtaactgta atcgagcttt ctggtgccat acaggtttcc ctcctatttc atttgttttt
    23761 ctttccgtga catgtacaca ttagtggaga tagctatagt tgcaacaatg ataaacaaaa
    23821 ccgaagacag tgctgatgca tagcccaatt cataaggtgc tgtaaatcct cgactgtaaa
    23881 tatattgaac agctgtttct gtcttaaatt gtgggccacc agcggttgca acatatactt
    23941 ggtcaaacac ttgcatcgaa ccaatcagat tcgttaaaat acaaaaacct aaggagggaa
    24001 cgatctgagg tagcgtaatg ttaaaaaact gctgtcgatt tgttgcacca tccatttgag
    24061 cagattcata caaagaggga gagattccct gaatagcagt caagagaatc gtcatagtaa
    24121 caccaaaatt cttccaaaca gtcatgatgg ctaccgtcgg catagcaagg gttggatcgc
    24181 gaaaaaattg agggatcggc aagccgactt gtgaaaacaa gtaaggaatc gcccctacat
    24241 tcggatcaag caacatagaa aaaataatcg caattgacgt caatgaacaa ataactggaa
    24301 tgtaaaatgt cgaacgacaa aaacgattga atctggtatt tttagataat gctactgctg
    24361 ctaataaacc aacgataatt tgtgttggcg tttcgagtac ggtgaaatat aaagaatgaa
    24421 tcaacgaatt aactgctcgt tcatcactaa atatacgtgt gaaattttca aaacttacaa
    24481 aatttcttga tgtaaagaaa atattcaaat ctgtaaaact aatagcaaat gttcctaaaa
    24541 gcggtatgac agtaaataat aataaaacta aaaaagatgg agttaaaaac aaatacgcag
    24601 cacgatcagg acgattccaa tatttggtga atccgttcat atagtccacc tcatctttca
    24661 ttttgataaa atatacaatc ttggtttaaa cgaatctgaa taagatatcc gaacaatcgc
    24721 tgtgattttt gcaataacac ctatctgcaa atactaggtc gatcattcag atatctgtat
    24781 cttgccaaca gtctatcctg tataaagttc tgtactattt ttgcagtaat tgattgatgg
    24841 catcatctgc atcgttcatg agtgtctcag gatcttctcc tgctaataat ttttcaatca
    24901 gtggattgat gatatcgtta ttgatcgcag agatttgggt aaaacctggt aaatatggct
    24961 ctgcatagtc catttgtttc gataattcag atacaatagg atcatttttt acttcttcat
    25021 cttttgctac tgaatccaag taggcaggaa aaccattttc gatactccat tttttaccaa
    25081 tttcagttgt attccaatat ttcaaaaact catagacagc ttctttttta ttattatctg
    25141 tacttgccgg aatggcatat cctacgccat ctaaaatagc tgtttttttg tctgaatcac
    25201 tcccttgtgg taaggtagtc acattataat caatctcgtt tgctttcaat ccgttattta
    25261 accatggccc attgatttca atggctagtt gaccagcatt cattaaattg tccatttcgg
    25321 cgccagaaat cgattctgga ccagtcttgt ctacatggat cattttttgg atcgctttta
    25381 acgttttaag gttctcagga gacgcaaatt cagacttagt ataatcatcg ttcactaatt
    25441 taccgccatt tgctaacatc cagttatata acggtgcagt tccatcctta ttgaagacaa
    25501 aacctgatac atttttacta ctatcagtta attttggtgc catttctgtc aattcttccc
    25561 aagtagtagg tggttgttca gtatctaatc cagcttgttt aaacaaatca ttattccaat
    25621 acatatacat gccttgtacc tgcatgggga caaaatactg tttaccttct acttcaccta
    25681 attcaatagc cgtttcttta aaatcagatt tatctactcc atcatattcc cagaaatcgt
    25741 ctaatggttg taccgctccg ttttctacat actgtgcaaa atctggataa tttaatgcaa
    25801 taaagtcagg tgctttttta gaagaaatcg ctgtaggaag tttttcattc aaattggccc
    25861 aagtcatgat atccatttca attttgatgt ttttatcatt tgttttatta aattcattaa
    25921 cgatttcttg caatatttca ccatcagatg cagtaaaccc attccaaaaa gtcaaagtca
    25981 cttctttatc agaatcagat tctgctgaac ttccgccacc gcaagctcct aaaatacctg
    26041 ttgcagctac caacaaagag ccaattaacc attttttacc tttcattttt tgttcctcct
    26101 tcatctgata aacgacatct gaccacattc caagatagcg gtttcaataa acaattgatt
    26161 ttcccatctt cagcttttac atttgttgaa tgacttggtt ttacttgttc acttttagga
    26221 agattagttg cttttgtatc aaatccactc atttcagaaa aatcaatcac tccctctaat
    26281 gataattcag acaagtgaac agttagattc atttcttctt ctccacggtt aactgcaaat
    26341 atgacaagtt ctttgtcatt tattacggct atactttcta aatacggcac ttcttcaaaa
    26401 tcttccgtcg catagtttgc tgaacgaatt tgtgggctta acacctctcc ttgtccatac
    26461 acagcagctt gcataaatgg ataatagatc gtctgtctcc aagcttctcc gtttgtttct
    26521 gtcctgattg gtgcaataac gtttaccaat tgagcaagac aagcaatctt tactctatct
    26581 gcatgtttca ataaagtgat taatagacag cctaatagta atgcatcttc aaaattatag
    26641 ttatcttcta gtaaaggagg agcaatctgc caaggcgctg cttgctcatc ttgttccgct
    26701 gaatgatacc aaatattcca ttcatcaaag gacaggttga tctgcttctt actatgtttc
    26761 ttcgccttga ctgtatcgca catcgctgtc acttcagaaa tgaaccgatc catgtctaag
    26821 gaacgtgcaa gataatgaga aagatcattt ttttggttgc cataatattg atgcagagac
    26881 aaataatcta tttgatcgta cgcttgatca agaactgtta actcccaatc accaaatgta
    26941 ggcatttgcc gattcgaact tccgcataaa accacctcaa ttgaatcatc tacgagtttc
    27001 atcgccttag ccgtttcctc tgctaaccgt ccatattctt ccgctgtttt atgtccaatc
    27061 tgccaaggac cgtccatttc attccctaaa caccatgtct taattccaaa agggctctct
    27121 tgaccattcg aacgccttaa atcactccaa taagttcctt taggaaaatt acaatattcg
    27181 actaaattac gagctgcatc tactccacga gtacccagat tgacagccat attgatttcg
    27241 gcccccacat gctgacacca gttataaaat tcatgaatcc caacttcatt cgtttcaatt
    27301 gtccgccaag ctaaatccaa ccttctaggt ctatttgcta tgggcccaat actgtcttcc
    27361 caacgaaatc ctgacacaaa atttccacca ggatatctaa tcatgggaat gttcaattct
    27421 tttaccaagt gaatgacgtc ttggcgaaat ccacttttat tagctgatgg atgatctggc
    27481 tgataaatcc cttcatatac tgctcgtccc atatgttcaa taaatgaact gtacaaccgc
    27541 ggatcaactt tgcctacacg cttgacacta ctaatcaaca ttgtggcttc cataactgac
    27601 ctcctttaat ttatacatga ataatacacc tcgttgaaag cgttgtcaat aatataaatg
    27661 ttaaacttac ttatttttta tcgattttaa ttaaccaaaa tattaataat gattaaaaca
    27721 aataatttaa tataactttt attaacaaat atgttaatat ataagaaaaa ccttttaaga
    27781 ggtgatatat atgcaactac aaataaacga agaatcctta ccggtatatg aagcattagc
    27841 tagtaaaaca aggatcaaga tcatccagct actttccaaa aaaaagatga atgtcaaaga
    27901 tttggcaaaa gaacttggag tgagcagtgc tatcacgacg atgcacgtga aaaagctaga
    27961 ggaagcaaac atcatcaaaa cagaaaaagt aggacaacaa aaaatttcga gccttcgtgt
    28021 cgataaaatc gatattagtt ttccagaaaa aatattcaat gcttttgata cgaaagaaac
    28081 atcgatacct attggtcact atacaaatta tgcaattgaa ccaacatgcg gtttagctac
    28141 gatccatgat tttatcggga aagtggatga accacgctat tttatggatc ctcgaaggat
    28201 ggatgcccgc attctctggt ttaccagcgg atttgtcgag tatcaggcac ctaatttttt
    28261 aaatacagag gatacattgg agatgttgga agtttctgtg gaaatttctt ctgaatttcc
    28321 tttttcaaat gacaattggc cttcagatat cactttcagc ctaaatggtg tggagctagg
    28381 aacatggacg agccctggag attttgctga tatccgcggt aaatatacgc ctgattggta
    28441 tccagataat cttaatcaat acggcttgct gaagacgatc cgaattacca aacacttgac
    28501 gaatatgaat ggagaaccct tgtcaaacat cacgatcaac gacatcccta aagagcaaga
    28561 cacttggcat ttgcgaatcg aagtgaaaga cgatgccaaa catgtggggg gctgtacttt
    28621 atttggtaaa ggattcggta attacgatca ggatatcaaa ttaaaagttt actacagctg
    28681 atatttttct tttctatttt ataaaacaaa aacagccaat ccctatgaag ggacggctgt
    28741 ttttgcttta ttgttatttc cagaaatcat ccaaaacgga aattggcaaa tgtcgtttat
    28801 gttgtgtctt gttccaccat gcttcgattt tttcttgtgc ttgagcggga acttcttttc
    28861 cttctagata atcatcaatt tcattatatg tgacacctag tgcgacttca tctgcaatca
    28921 ttggtttccc atcttcaaga tctgcagtcg gaatttttgt gtataatttt tccggtgcat
    28981 tcaatgcttg aagcaattgt ttcccttgtc gtttgtccaa acggaataat ggcaaaatgt
    29041 cggctccacc atcaccaaat ttcgtgaaga atccagtaat gttttctgca gcatgatctg
    29101 tccctaatac ggctcctgct ctttctccag ctacggcata ttgcgtaatc atacgttgac
    29161 gtgctttgat atttcctttg ttaaaatcgc tgattcccac acctgcttcg cttaatactt
    29221 gtacttgtgc atcaacagct ggtttgatat ttactcgcag actaacatcg ggctggataa
    29281 agtcaagagc agcttttgca tcttcttcat ctgcttgttc accataagga agacgaacag
    29341 cgataaattg atagttttca tcttttgttt cttcacgcat ttcttccatc gttagttgcg
    29401 ccaaacggcc tgctaaagta gaatcttggc cgccgctgat acctagtaca aaagttttaa
    29461 gaaacggata ttttttcaaa tatgctttca taaagtcaat acttttacgt atttcttctt
    29521 ttggatcaat tgttggtttg acacctaatt cattgataat ttctgtctgc aggctcattt
    29581 attctcctcc tatgcttctg tatgaagttc tgctacgctt tttttcattc gttccatgat
    29641 agccatttta tggttccagc attcagtaga cagatcgact gggtattttt gcggattcaa
    29701 gtctcgttta tactcttccc atagtgaatc tagattttct tttgtatatt ctttgatttc
    29761 gtttagtgca ggtaattcgt aaactctttt tccttcgata aagatatctt gtaaaactgg
    29821 gcgagctgta aagtctcgaa cagttttatt gataaacgta tgcactggat ggaacatgaa
    29881 gatagcttct tcttctcgag ggtcttcatc ccataatgtc acgtagtctc cttcagattt
    29941 cccatcaaaa tttcgagtga tgcgccacac ttgttttttc cctggagtag ttactttttc
    30001 tgcattgctt gataacttga tcgtatccat catttttcct tcatcatctt cgatcgatac
    30061 tagcttgaat actgcaccaa gggctggctg atcataggct gtgatcaatt ttgtcccaac
    30121 accccataca tcaattttag ctttttgcat ctttaaattc aaaatcgttg cttcatccaa
    30181 gtcattcgaa gcatagattt ttgcttccgt aaatccggct gcatctaatt gttcccgaac
    30241 acgcttagat atataggcca tatctccact gtcgatgcgt acgccttgga agttgatttt
    30301 gtcacctaat tctttcgcca cgcgaatcgc acttggcaca cctgatttca acgtatcata
    30361 agtgtcgact aagaacacgc agtctttatg ggttttagcg taggccataa atgcttcata
    30421 atcatttcca taagattgga ctaacgaatg agcatgggtc ccgctagctg gtatcccaaa
    30481 tatcttccca gcacgtacat tgcttgttgc atctgctccg ccgatatatg ccgctctagt
    30541 tccccagact gctgcatcca gttcttgtgc ccgtctagtt ccaaattcca atagtggatc
    30601 ttctccgatg acagatttga tacgagctgc ttttgtcgcg atcaacgttt ggaaattgac
    30661 catattcaac agtgctgttt ctactaattg gcagtgcgct aaaggccctt ccacttggat
    30721 caatggttca tttgcaaaaa ctagttctcc ttcacgagca gaacgaactg ttgctttaaa
    30781 ttcaaaattt tgtaaatact ccaaaaaacc ttcaggatag acttctaatc cacgcaagta
    30841 agcaatatcg gaatcattga acgtcagatt ctctaaataa ttgactaacc gttccaatcc
    30901 tgcaaaaacc gcgtatccgt ggttaaaagg catttctcga aagtaacatt caaaaacagc
    30961 atgtaaatca gctcgaccta attcccagta tgtctgcatc atattgattt gatatagatc
    31021 cgtatgcagc gtcaaactgt cgtctgggta agtattattc atcttgtatt actcctcttg
    31081 gcaagttttc atttcctacc cattataaca aaaaaaatta ataggaaaag aaatcttcca
    31141 ttttttctga aaaagcacat gttttacgga tatttcttgc taaaaatgaa ctccatctgc
    31201 taaaactatc ctttcttatt ggtatttaac ctaaacgaga aagaatactt attttattca
    31261 atgtatccga gacacgaaga aattagcgtt ttctattttt cttacttgat aaaataagta
    31321 gattttccta ctacaatcgt agccgttaag ataccgatga ttgaacaaat ataaccaaat
    31381 gtctctacaa cataatcaat ggcaaaagtt tttgaagcaa taatacgtct ttcctttttt
    31441 gcttcttatc cccaaagaaa cggatataac ttattatgta ttgaattttt ttggaaaggc
    31501 gaattatgac aagatatacc ttgcgttgaa aaaactcgcg gaaaaaatat cacacgtttt
    31561 taaaaagata caaagtaaga aagcagctgt caatagaatg gaaacaaaaa tggcgagaca
    31621 tcaatcagtc tcgccttgtt ttttattgta tacattagat atggagcagg ttaccataaa
    31681 gatgattatt agtcgttatt aaatagaatc cttcgtattt ttttgttcta tcactacaat
    31741 atctttattt ggacgtttga attgtattcc ggcacgttct agctcctgtt tcactcctac
    31801 atggactttg acatcttctc gtgtcatttt taaaacgtga tgaatcgcat agtcgatttc
    31861 ttgccttgtg atttttttct tcgtattgat catcacgact tgctttttat catatgtgtc
    31921 taccaatagc agttgtgttc gatctaacga aaataatttg taataattaa tagccgtatt
    31981 cccaaaaaag aattccacta ctttaggata aaatgtctta atatttaaat tactattcac
    32041 aggtgtttcg attagcttca tctcattcct cttttctata tagtcgattt agatccaatc
    32101 ttaagttatg ttaccatctt tcctagcatt aaggaatcgg ttacaattga acctttaaag
    32161 acaaaaggat ttacctttta tcacttaata gtataacata atttcatgag aaaaaaatac
    32221 aattttttct tgaccatctc gttacgtaaa ggattatgct tacatttgtc aggaggaaaa
    32281 ataatggagt acacaataaa gaaaatgtca gagatatcag gagtcagtcc gagaaccttg
    32341 cgcttttatg atgagattgg actgctaaaa ccagctagga tcaattcttc aggttatcgg
    32401 atttatggca aaaaagaagt cgatcgtctg caacacatct tattttatcg aacaatggca
    32461 ttcaagttgg atgatatcca agaggtctta gacaatccat cttttgacca ccagaaagct
    32521 ttaatcaagc atcagcaaat gttgctggaa aaacgggcac aaatcgatac cctcttgaca
    32581 actgtccaac agacacttga tatgtacgaa ggaggaagaa aaatgagtga caaagaaaaa
    32641 tttgaagggt ttaaacaaca aaagttgaaa gaaaatgaag aatcctatgg acaagagatt
    32701 cgacaaaaat acggaaaaaa aaaggttaca gcatccaatg aaaaatggat gaatatggat
    32761 aaagaaacgt atgaagaaat gcaaactgtt gaaaagcaga tgttatttga tctcactctt
    32821 tacttaaaag aaccagaaga tgaaagctta gcagaccgta tcttccaagc tcataagaag
    32881 tggttatctt acagctggcc tgaatatcag ccaaaagcgc ataaaggact aggaatgatg
    32941 tacgaagccg atgaacggtt cactgcatat tatgacgagc gaagtggtca tggtgcagca
    33001 aaagctttaa atgaaattat ccaaaaaaag gcgtaatctt ttacatgatc caacaaaaaa
    33061 gtacacgtaa aatgacctaa taacaaaaca gcagacaccc aagttagatt tttatgctaa
    33121 cttttggtgt ctgctccatt ctttcacaag ttttttcatc ctactttaaa tatattcatc
    33181 gttgaataaa cgtataaggt attttcactt tatccttttt ttctgtaaga aacaattgaa
    33241 atgccatttc tccgcaagct tccagatggt ggtcgatggt tgggaaacca agaagctcgc
    33301 tgatcagcaa attatcgcgt ccaatcacca ctggtgtctt atcttgcaga tagctttgca
    33361 agatgcctgc tgcaaccata tccgaatttg taaagacacc atcaactcca agctctttaa
    33421 aaaagaagcc tgcttgtttt cctttctctg catctataca atcccaaaaa acaagtgatt
    33481 catcaaaaga tggaaaaagt tgatgacata gctgcaaagt gatttttgag ttataactta
    33541 gcctgccact tcgccccaac gtgatgccca attgctttat accttgctgc ttcaaataag
    33601 taagaccttc tgtaattgat tgttctcgat caataaagac acagcttgcc tgttttccct
    33661 tgatttcttc acaaaaaact agaggtccat atttttgata tgccaataaa tcatctagtg
    33721 tattggcacg agacgtaatg atcaatccat cgaaagcttt agctgcaaat tcttcaagat
    33781 accttcgctc tttttctttc tgatagcccg tcggtaaaag tgtcactttg taatcataat
    33841 caaacgctgc ttcaatgatc ccactgatca actgatcaaa atacggatga ttggtataag
    33901 gcagaatcac tccaatgctt ttcgtttttc cataacttaa ctgtctggca tttgcattag
    33961 ggatataatc gacttctttc atgaccgcaa gtatttcttt ccttttttcc tcatctacat
    34021 atggatgtcc attgattaca cgtgaaatag tagaaactga ataacctgtg agctttgcga
    34081 tatctcgaat gtttgccact gctgcttcgc cacctataca aaaagatttt cttgtaaata
    34141 gtctaccaca gctggaccgc attcaaaaaa ctgatacatt tttccttcat gcgaaaaact
    34201 gatccgctgc ccgccccaat atatatcttt tgtcaaattt tcgatttcat tcattggtat
    34261 ttcttttact atattcctat tcaacccttg aaaactgtac aacgttaata cggatccctt
    34321 gaactcgaca aacgcataaa aataattgtt cgttgtgcca tctgttatct ctacataagt
    34381 attcattgca agccctcctt ttgatacttt gagtatagtg tatgaaacgc gtctcatagc
    34441 aaggagtttg ttttgccaaa gaaaagtttt attcctcttt cattattacc aaagtctctt
    34501 attttaaatt gaatacatta taatgatact gtaaatatat ctttattatt agtgaatgga
    34561 tatttacttt taatagataa aatattataa ctattaaaaa taactatttt cattataatt
    34621 acacacaaaa aagagcgtga gacaaaagta aagaacactt ttgtctcacg ctctaaacac
    34681 gtataaacag cggaagcaga agcaactcct tcggaaataa gctgaaattc acaaaaattt
    34741 gaaaagcaat ttccgtgaat ttcttcttat ttcttggagt taaacgcttc tgttccagcc
    34801 tctttttatc tgtctttcac taatgatcag ttgtagataa gcaagttgct ttttcttaca
    34861 tcataccgcc catcattgat ggatccattg caggagctgc tggcgctgct ggttctggtt
    34921 tatctgcaac gactgcttct gtcgttaata acaaggcaga aacggaagcg gcattttgca
    34981 aggcagaacg tgttacttta gttgggtcta cgatacctgc ttcaaccatg tttacccatt
    35041 ctccagtagc agcattgaaa ccagtgccta gttccacgtt cttcaattta tcaacaatca
    35101 ctgatccttc ataaccagcg ttttcagcga tttgacgaat tggttcttct aaagcacgaa
    35161 caacgatctt gatacctgtt gccacgtctc cttctgcttc tacagcagaa actttgctga
    35221 taacgttcac tagagctgta ccaccacctg agaccattcc ttcttctact gcggcacgtg
    35281 tagcattcaa tgcatcttca atgcgtaatt ttaattcttt caattctgtt tcagtagctg
    35341 caccaacttt aacaacagct acaccacctg ctaatttagc taagcgttct tgtaattttt
    35401 cgcggtcaaa atcagaagtt gtttcagcaa tttggttttt gatcaattgc acacgagctt
    35461 cgattgcttc tttttctcca gaaccttcta cgatcgttgt attgtcttta tctacaacaa
    35521 ctttagaagc atttcctaag ttttcgattg ttgcatcttt caattctaaa cctagatcgt
    35581 cagtaattac tgtaccacct gtcaaaatag cgatatcttc aagcattgct ttacgacgat
    35641 cgccgaaacc aggagctttt acagctacta cgttgaatgt tccacggatt ttgttcaata
    35701 caagagttgg caatgcttca ccatctacat cgtcagcaat aatcaacaat ggacgtgatt
    35761 gttgcaagat ttgttctaac aatggcagaa tatcttggat gttagagatt tttttgtctg
    35821 tgatcaagat atatgggttt tctagaacag cttccatttt gtcgttatct gttaccatat
    35881 attgtgataa gtaaccacga tcaaactgca taccttctac aacatctagt tctgtttcga
    35941 tcccttttga ttcttcgatt gtgatgacac cgtcgtttcc aactttttcc attgcatcag
    36001 caatcaaatg tccaacttta tcagaacccg aagaaacagc tgctacttgt gcaatggctt
    36061 cttttgaatc aacaacagtt gagatattat gcaattcttc gactgctgct tttgttgcca
    36121 attcgatccc gcgacgaatg cctagaggat tagcacctgc agttacgttt tttaaacctt
    36181 cgcgaacgat tgcttgtgtc agaacagttg ctgtcgttgt accgtctcct gcaatatcat
    36241 ttgtttttga tgctacttct gatacaagtt ttgcacccat gttttcaaaa tgatcttcta
    36301 attcgatttc ttttgcgatc gtcacaccat catttgtgat caatggagag ccgtaagatt
    36361 tttctagtac gacatttcgg cctttaggtc ctaatgttac tttcactgta tctgctaatt
    36421 tatctacccc gcgtaacata gctgcgcgtg cgtcttctgc aaatttcaat tcttttgcca
    36481 tgattgattc acctcattga ttatttttga ttattttttt atcttccaaa tttactcaac
    36541 aatcgccatg atatcttttc ctgcgacgat cagatattct tttccttcgt attttacttc
    36601 tgtaccggcg tatttttcga acataacttg gtcgcctgct tttacagcgg caggaacttt
    36661 ttcaccgttt tctaacaaac ggccttcacc gactgcaaca actgtcccag tttggggttt
    36721 ctctttagca gcagaagcta aaacgattcc tccgacagtt ttttcttctt cttttgcgac
    36781 ttcgataatg acgcgatcac ctaatggttt taacacgata aatccctccg ataactcttt
    36841 ttttaatctg ttagcactct taaccttcga gtgctaacct acatttttaa taatactcat
    36901 tctccctctt ttttgcaagc ttttaaatca aagaaaagaa attttattct gacagctgct
    36961 tattgaaatt atgatataat tgaaatcaat cgatataagc ttgccttgca tgcttgttat
    37021 cccttaaaag gaggaattac atgtctttaa aaaaatatag cttcctcagc attttttgct
    37081 atggtctaat ttttatctca cccttgatcc tagcttcgat aggacttgta aaatctacgt
    37141 ctgaattgat cacagcaact gcagtcatgt atatactagg cgccgttgtc ctagctattt
    37201 tttattttaa gcaacgtgaa cccttagcga tcgaatcagc ggtaaaaaaa gcttctgctc
    37261 caaagattgt tatttatgga ttggttggaa tctttgtcgc attgattctg caaagcatcg
    37321 ctgtcatgtt agaatctgta ttgtttggca aagcaacccc ttccgagaat acacaaaata
    37381 tcatccagat gatcatggaa gcacccgctt ttattttggc gacaactgtt gctggaccca
    37441 tcatggaaga gttcgtattc cgccgcagta tactggggat catcagtcga tattcaaatt
    37501 tttgggtcgg agcagtgatc agctctttgc tgtttgcgtt tgctcataat gatggtcatc
    37561 tgctaatcta ctttttccta ggtttcttct tcagcctaga gtacaaagca actggtcgga
    37621 tctggacatc gatgatcaca cacgtaggaa tgaacacatt agttgttctt gttcaattag
    37681 ctgtccaaaa agggctagta taaacatgac tataaatact cctgtcatcc tagattggtg
    37741 attttcccaa tctaaagcga caggagtatt tttgtttttt agtcgttcat cttttctgct
    37801 gctccatcat tttttgtctg tctttccttt ttgcagtttg cagaatctat ttttttcaaa
    37861 aatgggaaat aaatgaaaaa actaattgac aacacgatac cttgtaaaat cgctgcaggc
    37921 actccgccta ctaagaaacc cgagaggatc ggcggtgttg tccaagggac ttggactgct
    37981 gtaaataaag gaacgaatcc aaaatataaa gcggaatagg taatcaatcc tgaaacgacc
    38041 ggtgcgaaaa taaaaggaac agccatcatc gggttcatca cgatcggtgt ggaaaaaata
    38101 attgattcat tgatgttgaa aaaggctggt aaaagagcaa gatttcctaa ttctctgtat
    38161 ttcttcgatt tcgcaaaaac cgtcataaaa aatacagccc ctaacgtcaa tccagcaccc
    38221 gtaaccgtca tgaactgatc gagaaattgc tgagtaacga tatgtccgcc atttgccacc
    38281 gtcaactctt gtcctgaggc taagatttct gcatttgcta atgaattcgc ttgcaagacg
    38341 ggactaacca acccattgac catcgcagat ccatgaagac caaataacca taaaaacgga
    38401 acaaaaaaac ctaataaaag cacaccaaac aacgtgtcta tgaacgattg aatgggaagc
    38461 tggacatatg tccatactcc ttgaacaaca gtcattctga acaaatgttg aaaaaccgct
    38521 gaaccgataa gcgtaaaagt gactataaca atgattggaa tcaatgaagt aaaagactgc
    38581 caaacatttt caggtatctt ctctctttgc ttccaccctt tcgcaagtct tactaaacgt
    38641 gcatagcccc atccgatgat gagcccagtt gtaactgctc ctagtatccc ttcagcacct
    38701 gtccagacag tatctatctg agtatttagt ggctgaataa gcagtagata agcagacaag
    38761 gctgttatgc cgactggtaa gcgatcgatg tcttcttctt ttgcataagc gtatgcaatg
    38821 gcaaaaacga tccaaaaggc tatcacatca aatgtagcct ggtatacttg tgtaaaatac
    38881 atagaaaatc ctgttttgtc tatccactga gcgatgtaat ccacaggaaa atgagcaaat
    38941 aagaaaaaca gcgagccaac aataattatt gggatcgtgt aagtcattcc attacgcaaa
    39001 gcagttaagg gtctaagatt cacaacagat gttatcattg gtaaaaaggc acgatctaac
    39061 cactctttca tttcttatct ccttcaactt ctatttttat caatcagttt tcttaattta
    39121 actataccca atgatcacga accatgaaag gaatgcgcac tgagcttttc aaaaatcgga
    39181 ttctttgacg aatattcagc aactgcttac aatggacagg aataaaaaag gaggtttttt
    39241 atgaaaattg cactcattgg agctactggc catgcaggtt catttatttt agacgaagca
    39301 ttgtccagag atttagacgt gacggcaatc gtgcgtcatc cagaaaaatt gccatcagat
    39361 gttccgttta tacaaaagga tttatttgag ttgacaacta ctgatcttgc atcttttgat
    39421 gttgtcgttg atgctttcaa cgctcccaaa ggaaaagaag aaatgcatca aacttctttg
    39481 tcccatttga ttgagatgct tgaaggaacc gatacacgct taattgtcgt tgggggtgcc
    39541 tcttcgttat tcttagatac agaaaagacg actcgtatga ttgaccaagt acctaaaaat
    39601 gcacccttct atccaacagc tttcaatatg tacgaaggat tgttaaaatt gaaacaatct
    39661 aaaaatctac attggactta tatcagtcca gcttctttat ttgatccaca tggcaaacgt
    39721 acaggtactt atttgttaag tgatgattat ttacaaagaa acgctgctag cgacagtacg
    39781 atcagcatgg cagattacgc gattgcatta gtagatgaga tactggatga gaaacatgaa
    39841 aagcagcaca tcagtgtagt cagtcgataa tacggttatt tttttaatat gctaaaaaaa
    39901 taaaaataga agataaaacc aaccctgatt gattttatct tctgcttttt atatttttat
    39961 tgattgaact gtttaaatcg aaaatagctc agttgcttca tctggatctg tatcatagat
    40021 ttcaaaatca tgtccaacgc caaaatcttt ttctttcaaa acattttcca ttgttaaatg
    40081 agcaagttct ttcatattgt tttccttgct aagatggcca agatagattc gtttggtccg
    40141 attaccgatc acatcagtca tgacaagtgc accgtcttcg ttggaaagat gtcctctatc
    40201 tcctaaaata cgctgtttta aattccacgg ataaggtccc atgcgtaaca tctcaagatc
    40261 atgattactt tccatcaaat aaccatcggc attttcaatg acacctcgca tataatcact
    40321 gcaatatccg gtgtccgtca acatgacgaa tgaccgattt tctttatgga aacgataaaa
    40381 ttgcggagcc gctgcgtcat gggagacgcc gaaactctca atatcgatat cgccgaatgt
    40441 tctgactttc cccatctcaa atagatgttt ttgttccact ggtacatttc caatcagtgg
    40501 ttccatcgct tcccaagtct gctgattggc aaaaacatcc aaatgatact tacgagccaa
    40561 gacacccacg ccatgtatat gatctcgatg ttcatgcgtc acaagtattc catctaattg
    40621 gtccggtgtc cgatcaattt gagccatcaa ggaagtgatt tttttaccgc taagtcctgc
    40681 atcgaccaaa agccgttttt tttcactttc gatataaagt gaattacccg aacttccact
    40741 tgctaggata ctgattttaa aagctggttt ttcttcagcc atttgactcc tacttccctt
    40801 cttactttgt aaactttttt cattatactc gcttttttat tgatcttcca cttttggtac
    40861 agtattgttt gtcacgatcg tattgctgaa agcgttgacg ctctcaattt ggaccacttt
    40921 atcgcttgtt tcgatcgcta catgccaaac aggaacatac acattttttt cccggacttt
    40981 cagaatacag gaataagcta gctgacgcca taaaattttt gatcctcttg gtattttgtt
    41041 attgatgtac aatgtattga ttgcttcctc ttccgtatac agttccgtct tttcgcgcag
    41101 ctgctcgata tcagataaat gcgtctgcat gtatttcgtg atgctataat cattatcgtt
    41161 tttttctaaa gaaagaacga tttttgctgt atcatcattg aatgggatgc cttcatactc
    41221 ttggcttgct tggatttcta gtggttcttc ttctaaatga gaaaagtttt tcgtgtacac
    41281 ataatcatta ccgaataaaa tattgtcttt gttagataaa aaatcttcca aggaactact
    41341 aattttatct ggatcgatca cgttcttttc agcatctgaa ctggataaag atttcgtcaa
    41401 aacatcaccg tctaaaaaca caccacttgc cagcaagccg cttttaccag ccttgcgata
    41461 attcgctaat gaagtgctaa gattggtctg ctccgcgcta agataatagc cttgcttgtt
    41521 ctcagacgaa atcttccccg tgtaagtgat atcgtcgcta gccagacgtt gttggattga
    41581 ttcagtctga ttagagcgaa tgacattgtt ttcttggtat accgcgtcat gataactgct
    41641 gaataaaaac acattcaacc ctaaaaaagc gacgaaaaat atccattcga tttttttgaa
    41701 atccaattaa ttcgcctcca atccaggtaa tttttccaga aggtcgttag ctgaatacca
    41761 gttatcttta tatttcacat accattcagg taagagatca acgacacgat tcgtttcttt
    41821 gacattttgc catgtatagc caacgatcac tgaaccaatc ttgttgctat ctgctccctt
    41881 agcttttaac tgctggatga tttcattcgt acttgcaagt tctacttctt cgtctgaagg
    41941 tatcggcact tgaatcgtat tcaaactggt ttggatattc acttgcacag aaccattcgt
    42001 ttcaccgcca acttccacac caatctgtcc tctgctgtct gtcccaaaaa ccgggaagcc
    42061 ttccacgaat atccgataat cgatcgtatt gtcactgcgg tcaaaatatc tgaggttccc
    42121 taaagaactg cctaatttgc taatataggg gaaactttca gaaaatacac tagcattttc
    42181 ttttttctct ggcagctctc cacgaaaatc aactacttgc gtttccgaat ggatagacat
    42241 tgtttcattc ccaccgtaaa aaatcaattc attgctttca tcattatttt tcacgctatc
    42301 tggtttctgg aaaaaagcat ttctaaaaag tgtatagggt tgctgtgaca ggatataact
    42361 atacttcttc agtttgatcg aatgtttcgt agcatattgc gtgtcgatcg tcgatggttc
    42421 tgttgtcatt tctgtccatt ttgtgtcttt tgctgttaat tctttattga tatctgtcca
    42481 attcaacgaa atatttgctt catatacgag atggttcgaa taattcaaaa atcggatttt
    42541 tttatttcct tgatcgaatt gtattctagt aaaatacata ttttcgcttt cttttgccaa
    42601 gttcgacaca tctaaatcta aatcaaatgc ttccttgtat tctcttagca aaaaaggcgc
    42661 attataggcc aactcaaaac cagagttcag atttttcacc tgttcaaact gtgatttgtc
    42721 tcctgaaact acttcagaaa gctttccaaa tcttgcttta tcgatgatca attgcaatcg
    42781 gtacacgaga ttttcactgt tggtttcttg gatcattccc gaatggtgcc atgtaacatg
    42841 aagcggaaga aagacttcgg aagtttttcg attgctttga gactcgatca tttgagtgtt
    42901 tgtctcatct acgttgattg aactttttcc tgctgggctc agccagattg cataagagaa
    42961 gtatatgctt aacgcaacca tcaaaatgag tcctatacga acgacttttt cagagattct
    43021 cattcccacc attcctcctc ataaggttca tatggcagcg agatataaaa agtcgaccct
    43081 tttccttcct tgctctctgc ccaaatagcg cctcgatgcg ccttaatcac ttctctagaa
    43141 atagctaatc caagtcctgt cccaccttgt gctcttgcac gtgctttatc tactcgatag
    43201 aaccgctcga acactcggtt cagatctttt ttaggaatcc ccaatccttg atcggtgata
    43261 cttaaaatca cgttattatg cgtttctaat aagcgacaag taatcgttcc cccatctggt
    43321 gaatacttga tcgcgttatt catgatatta tcgactactt ggatgatttt atctgtatct
    43381 acttcgaccc aaagatctct ttgcgtaaat tcacgacgga tcttataatt tttttcctga
    43441 tttcccacca tcatatcaaa ccggtcaaga acaaaattca ctaactcgtt gaaattgaca
    43501 tattctaatt gaagctgggt attacctgta tccatgcgag atagatttaa gaggtcattg
    43561 atcattcgaa tcattcggtc tgtttcatct agcgttacct tcaaaaaatt tggtgctact
    43621 tcctcgtctt tccacgcacc ttcgctcaat gcttcgatat aactacgcat acttgtcaac
    43681 ggtgtacgaa gttcatggga aacattagag acgaattcac gacgttcccg ttctgttttt
    43741 tcttgttctg tcacatcatg caagacagct actaatccgc tgataaaacc tgattcgcga
    43801 cggatcatag aaaagtctac tcgcaagatc atctgatcac tttccaatgt actggttgaa
    43861 cggtcaagta ccatttcgtt tggatcttct aataatttcc gcaacgtata ttcttcttcg
    43921 atatctaaaa gtgtcaaaat cgattgtccg attgcttcct cgtttttgat atctagcaag
    43981 gaaacagcca tatcattgat cgtaatgact ttacccctgc gatctgtcgc aatgacgccg
    44041 tctgtcatat gggatagcac gctatccaaa cgattgcgtt cagcttccat tgtatcttga
    44101 gcttcttcaa tacgttcagc taactgattg aaggtatcag ccagctgtcc aagttcatct
    44161 tgtccatgca ctttgacttt ccgactgtag tctcctctag cgattcgaat ggcttgttct
    44221 ctcatttcac cgatcggctg tgtaatcgaa cgagcaacta aaacagatac gatcattgaa
    44281 ataaatgccg caattagtga ggcagtaaag aaaatgactg ctgtgttatt gatttccgaa
    44341 tatttttgtt cgatattact tttgacgtaa agagccccga taacggcatc gccggtcggg
    44401 gacaggatcg gttgaacatt gatattcacc cgtttatcgt cgttatctaa agcaacataa
    44461 cgtttagtcg tgaaatcatt gatatcaaca taatcatttt tctttcccac agcgctttgt
    44521 tcattgacat cggttgttcc tcggatgatc cctttttcgt caacgacccg tatttcgatg
    44581 atatcgctag tcgcactgtt ttcaataaat cttttgatat tcgcatttac ctcttcatca
    44641 tctgcattat cttttcgatt caattccggg ctgattgttg ttgctaatga ttccaccgtt
    44701 tgattcatat ctttaataaa tgtattgatc gtggaacgtt ctaaaccacg tataaagtag
    44761 gcaccaataa tttcgatcga gatcaataaa atcagaataa aggtaatagc gatcttaaaa
    44821 ttgactgatc gaaaaaagcg gacttttctt ttcatccaat tactcctgtt ctgggttacg
    44881 caaatagtaa ccgacaccac gacgtgtcac taaataattt ggatggcttg gattatcttc
    44941 gatcttttca cgcaaacgac gtacagttac atccactgtt cgtacatctc caaaataatc
    45001 ataaccccaa accgtttgta ataaatgttc tcttgtcatc acttgtccaa ggtgcttcgc
    45061 caagtaaaag agtagttcga attcacgatg tgttaactcg attgtttctc ctcgtttcgt
    45121 caccatgtaa gcttctggat ggatcgtcaa atcaccaatc gtcaattccg caggtgctgc
    45181 ctcttctggt tccttcgcag ccgtggcacc gcgacgaaga tttgctttga cacgtgcaac
    45241 taattctcgg ttggaaaatg gcttggtcac gtaatcatcg gcgcctaact ctaagcctag
    45301 gactttatca atttcagaat ctttggctgt taccataatg atcggcatat cataagtttt
    45361 gcgtacctca cgagcaactt ctaagccgtc cattttaggt agcatcaaat caagtaaaat
    45421 caaatcaggt tctacctcag caactttttc caaggcttct tccccatcat atgcagtata
    45481 aacgtcatag ccttctttgg ctaaattgaa tttgacgata tccgaaatcg gcttctcatc
    45541 atcgacaact aaaacttttt tcataaagag ccacctctta tatattattg tcataccttc
    45601 tcattatacc gtatttctgc ttttgtttca tctttgccta taaaacaaaa gagaaaatta
    45661 aaatgaaagt gcaaaatact ttattatttt ttgttctaac ttcaataaaa aaggaaaaca
    45721 ctgattttca cctcagtgtt tccttttttt gatttatcct tctaaaactt gtacaccgac
    45781 acccaataat cccggaccag tgtggactac taatgccgga gaaatctggc caaagtagat
    45841 ttggtttgct tgtgggaact ctcttttaag tctcgcttcc atttcaattg cttcttcttt
    45901 cgcatcccca tgggcaacag ctaagttgaa gacctttgca ttaccgattt tttctttgac
    45961 gtaagcaacc gttttatcca aacttttttt acgtccccta gcttttccta ctgtgtaata
    46021 aatcccttct tcattacatg agatgattgg gttaagcttt aaagcggttc ctacaataga
    46081 agcaactaaa ccgatccgtc cacctttttg aagatattcc aatgtcgcaa cattaaagaa
    46141 aacttttgtt ctttcgacta actcattcag attactgatc agttgatccc attctactcc
    46201 ttcttccagc cattttgctg cttggatcgc agaaaaacct gcaccaatac caatattttt
    46261 cgtatctagt acatatgctt ccaattcttc ttgctgttgt gcaattaaac gaaccacatt
    46321 atatgtcccg ctcaatccac tggaaattgt taccgcaagt accttttcat aaccgtcttt
    46381 tttgatttgc tcaaagattt ctgtgatcga ctcaccatcc ggcaaagatg taccagggat
    46441 ttcctctggc aaacgttgat agatctcttc aggggtaatg tcaattttat ctgtatatac
    46501 ctgatcttta taaataattt tcaatgggat catatacatc tcgtattttt ttatcaattc
    46561 ttctggaaca tccgtacctg aatctactaa aattgcgatt ttattgtttt tcatttgttt
    46621 tctcctcttt taaatattcg gtttctagaa caatcgtttt ttccgcaaga agtttcattg
    46681 caaacgataa agttgccgct cttacagcaa tatattctac aggggttgcc tggtcgaatt
    46741 tttgcggatg agatttacct tgtgctaatt ggctgaccat ccacacagct gcttcttgtt
    46801 catcgcaaaa tagattatag gcttcacgaa ttcctactgt ttttccttgg aacaatatcc
    46861 cttctttgat ttcaggaata gtcaatactt gtttcaacgt agtgattgca agtaaaaatg
    46921 ctacgtgttc tttgttatat ctttttttaa ctggtgctgg tatcaaacct agtttaacgt
    46981 aattgtttac catagaagag gtaagcaatg gatgcttttc tccttgtatc acaggtgaaa
    47041 gataacgatc aactaacgtt ctgacttggt ccatataaag ttctaagtca gggagttctt
    47101 cccagtgagg cagacggaat gtttctagtt ccttccccca ctccattaat tgctgacgca
    47161 ttttttccat cataaccgct ccttttttca tttcataaac atgatatcag acttatgata
    47221 aacattcaat ctagttgctt taactaggtg atttgattag cgggattcta tgaaaacaaa
    47281 aaacaagaag gctaagcctt cttgtctttt atcgttaaga acaggagacc cgccggggag
    47341 acggcgggaa aggagtaaaa aatgaaaaaa gtgttagggt ttgttctctt gcaagaactt
    47401 tgtttgttgg tatgcttata taatagcgag caaatgtgaa taatctatga atgatttcct
    47461 ataaggaagt aaagattttt ctgattttct ttaaatgtag tcttgcattt taaaattctt
    47521 agtgctacta ttattaagta ctttttgtac gggccgttag ctcagttggt agagcagctg
    47581 actcttaatc agcgggtcgc gggttcgagc ccctcacggc ccattgggtg ccaaacccac
    47641 ggaacaggta aatgttggtg cgaaagcatt tcgaaaacat ttacgctgtt ctttttttat
    47701 ttttcaaaat aactagggct ttttattttt aactcaaagt ccactgtagc cctttggact
    47761 ttgagttaaa aaagaagcat aattatgaac agtaaagttt ctaatataac aataattcga
    47821 gaagctttgc aaaatcatgc tgccaatgaa ctctctaaac atataggatt aaatctaagt
    47881 actataaaag gttaaaaagt gaagaatatt taatagaaaa actaaattta cttgctgctt
    47941 tccccttttc cattaataca acaatcagag agtgtctttt tttcgaaaaa attagaataa
    48001 ataaaagaca cgtagttttt ttatctacat gtcttccatc gactacaagt tatcatttct
    48061 caaaacgtat ttagctttta attgattaat cgtttcacgt tgtctacaca ttgcctaatt
    48121 aagattttct tattagaagc atcaatcccg caataatacc taaaactcca ggaattaccc
    48181 acaataatgt taaaagaaaa aatggaataa tagataaaat gagtaaacta ataccataga
    48241 ccactgtttt ttgatttttt cttactaaaa aacctattat gaaaatcatt atcgaaaaaa
    48301 ctagggtaat tcctccaaat aaaacaacat tcccgcttag attgactaac atatctatat
    48361 ccttactggt tagttctgta gtatttaaag tagttgaatc aatagaagat agaaacatac
    48421 cacccatcaa tgctaaaaga ctacataaaa tccctgttat tccactaatt aaaatcaaaa
    48481 taaactctgt ttttctctta ttcatttaat tctctccaga ttaagtgttt tagaattaga
    48541 aattttttga ccatagttaa tagcttctaa tgaacgaata acaaccactg acgtgttaga
    48601 aaaataatcc ccaatatgtt gtttcttggg cgtgaaagca gccaccaaat acccaatttg
    48661 aaatacaaaa ttttttaata taaacctaca tatacactca cgaataaaga tagtttgcca
    48721 acttagctct ttttcctcaa agctcactac tcttatccca aaaatcattt tcccaattgt
    48781 ttgtcctgaa ttcagcttag tcaaaagtac aaaataggtt aaataaatag ctaatgacgc
    48841 tataccataa aaagtaataa tggatttgtc agattccagt cccatgattt tgtaaaagag
    48901 acctatagta gcatgggtga tgatgctaat acaaattaaa tcaataagaa aagcaaaaaa
    48961 tcgtaaccaa aatcccgcaa atacataatt aggcaaagtt tcaatgccac tcttcttatt
    49021 cattttatag ccctccatag taatacattg gttttggagt atcagaaaat ccaagttttt
    49081 caaaaactga aattacacga tctgatgtag ttgcctttag cccttgccat tcagcaatct
    49141 tattacctaa ccaagaagaa gcaaagccag ttgtgtcatt tttatattct ataaccgtcg
    49201 catcagttaa tttcttctct ttttttaggg aatctaatgc atcttcagag taaccaattt
    49261 gatccaccaa cccattttct actgcttggt taccatcata aattcttcca tccgcaagtt
    49321 ctttcactgc attagtatcc atatttcttc cttttgctac aacattgaca aaacgatcat
    49381 aagcactcat cacaaattcc tgtataactt tattctcttc ctctgaaggt ttgtgttgag
    49441 gtgacatcat atcttttaat gcaccacttt tatacgtcgc atcagttacg ccaagttttt
    49501 ctaataagcc agaataattt aaaccagaaa taatgacacc aattgatcca gttgttgttt
    49561 cttccgtagc aaatatttta tctgaaccag cagaaatgta gtaccctcca cttgccgctg
    49621 tatttttaaa tgcagtatag ataggaatat ctagcttttt aatttttgcc atttctttag
    49681 caatctcagc actttcatat attcctcccc caggtgaatt tacttctaat aacactccct
    49741 taaccgcttt gtcttcttga attttcttta gctgtgttaa aaaattctga tggttatatt
    49801 gttccctact aaaaagattg ctttcacctg tatctgcaat aactccattg acggatagtt
    49861 tgacaatctt tttatttgat gcgccttctt ctaacgtttc ttctgtgatt tcgttagatc
    49921 cgtaaaaaat cttatttatt cctgttaggg ttgtatttga tgcttcctct ttatcttttc
    49981 ctggaattag cgcgacgata atggatagta acaataatcc gcacgctact cccacagcaa
    50041 tccatcttct tttattcata taaactcctc ctatattctt agtaaaaata attatttttt
    50101 atttagaaac acatcgacaa tttgttgcca atatgttttt tctcctacaa ttaaagacaa
    50161 ctctccagtt aatccataac gaaacggaaa cgattgagtt gtttttaacg ttcctttcac
    50221 tgcataaaaa acacctttct cagtggcagt agaattttct gaaatttcat ctaaagttcc
    50281 gtcgatcgta atcggagccc cacctttttg atccaattta aaatgaacct tcatcccttc
    50341 tttaatatag gtactttcat tcgcaggtaa aagtgctgta aatttcattt ttgatttttc
    50401 gtggatcgga taaatttctg caagcactgt tcctttggct agttctgctt gtccctttgt
    50461 ttcttcattt aaatgaaccg ttccagatac aggagctttt agtattcctt ttgaaagttg
    50521 atcgtccaaa cttttgataa ctgactggtt cttctcttgt ttttcattta gctctgtaac
    50581 tgtttgtttt acagttgtta ttgcttgttc tagctcttgc tttccttttt ccgtttgact
    50641 aattctgtca ttctcagaag tagttggttt aactaattta gctttttctg actgatactg
    50701 ttctacttct ttttttagtt gctcaatttg ttcatttatg cttgctgaaa ttgtcagttt
    50761 cacttgattt ttttgatcat cagaaacatt atttagttgt tcttgccaat tctcatagtt
    50821 tgccatcatt tcttttgaaa aatcttttaa tgattgatta ttactccaag ctacctgtac
    50881 ttgttgccat tcttgtaatt tactatctga actctcaatt tgtttttcta gttgtctttt
    50941 tgtcttttcg tatacttcta attgcttttg atcatttaat tcactttgct tcaaagcgta
    51001 gcggagtgat tctttttctg acaacatgct ctttaattga ttactgtagc caaaactgtc
    51061 atccgttgaa aacaaatttt ttcctttact tatactttca ataaatagct gagccatctt
    51121 tatttgttga gtaatacgtt ggttttcttg ttctatctga gccttttcat tctctattaa
    51181 agaacaatcc aatctaacca acacatcgtc cttatgaaca aattgatttt cttttaggaa
    51241 gttttccatt attttagctt ctaatggcac ttgtaacttc tctatttttt cggggttcaa
    51301 ttgagccgtt gtccgaataa caacctcttt tttagcaaag gttaaaaaca atccaataat
    51361 acataaaaaa agaattacag ggtataacac ccaacggtag aagctatgat gttgtttagt
    51421 atagatacta gaatgttcga accaattatt attctgcata aattgtttcc ctctcctaga
    51481 tttcccataa tttttgatag ataccatcgg caaaacgaag ttcatcgtgc gttccttttt
    51541 ctaccaaatg cccttcatgg agaactaaaa tttgatcaca tgcttttgct attggtaaat
    51601 gatgcgcaat aaaaataatc gttttttctt ttaaattgag gagataattc ataattgcat
    51661 gttctaacaa ggtatctaat ccactagttg cttcatctaa aattaatatg tccggatttt
    51721 ttaataaagc ccgtgctaag gctaatcgtt gtcgttgccc tcctgaaaga ttatttccac
    51781 cttcttccaa caatgtctcg taacgtaatg gctgttgatt aataaattca tttagttgga
    51841 ctatctcaca aacttctatt atttgttcga aacttggtgg gctatctaaa ccgaatataa
    51901 gattctcaat gattgttcca ctaaagaaaa atgactcttg aggcaaatat gtcactcgat
    51961 cgcgtaatat ctgaaaagga atgtctaagt gattaatgtt tccataatgg atcgatcctt
    52021 ctgatgcttc ataaaaacga acaaataact ttgcaagagt tgattttcca gaaccactaa
    52081 ctccaactat agccgtttta ctgtgcgaag gaattgtaca tgaaatttcg ttcaacgttg
    52141 gggccttcat gctatacgag aatgaaacgt tttttacagt gatatcttgt tgaaataatt
    52201 gttcagaaag catatattca aaagactggt tcgatttttc tgaatcaatc gcgaaaattt
    52261 catttaaacg attatttgca acttgagccg tttgcatttt cacttgtaaa ttaataatgt
    52321 tttgtaaagg atctgtcaaa aatactagta aagcattgta tgtgataagt tgacctagac
    52381 taattctatt atccataaca aaataagaac ctagccataa aattaatgca ctgctaatta
    52441 attgaatcaa atgtttaatt ccttgttgaa tattatcaag cgtaaccgta cgaaatgatt
    52501 ttttcattaa tttaacaaat tcatggtcta tacggttata tactttctct tcaccgctat
    52561 atgctttaat tgtttctatt cctttaagac tttctatgat actagaattt acagctgcac
    52621 cggctgccat ttcttccctg ttcgattttt catagctttt cacgaaagcg aatattgcaa
    52681 ctacataaaa aggcaaagag catagagtga ttaaaaacaa cgtactattc tgaatagcta
    52741 acgtaacccc aacaagcaac accataccaa tatctaaaaa tattgataac gtagcacttg
    52801 ctaaagcatc aataatctta ctggcatcaa gaaaacgaga aataatttcc cctgattttc
    52861 tcgtagcaaa aaaattcatt ggtaaagtta acacatgttt gaaatactga agcataattg
    52921 ccatactcat tcgctgtcct aaaataataa gaagataact acgactatat tcaaacaata
    52981 cccgaaataa atagacagcg atcaagccaa tggaaattat atttaaagtt gaacgtgctt
    53041 gattagggat gaaaaaatca agaatacctt gaaaataata tgagcttcct atgccaaaaa
    53101 acgtaatgaa aatcgatgct aaaacgatgt ggaatactaa tcctttttgt ttccaaatta
    53161 taggcaaaaa agaacttaat ccagctactt tttctttaat aggaatataa gtttctctag
    53221 gcataggtaa taaaagaata cctgtccatt ctttttgaaa cgcttcaatc gtttttctat
    53281 tttttccatt agcgggatct gcaatccata gtacgtttcc cttcgtttta taaattacaa
    53341 cgtagtgcat atagctgtta tcaaccaata tatgtgcaat taatggtaag ataagatctc
    53401 tttctttcca gatctcacta tctgcttgaa tagccataca atcaaaagac aatttttcaa
    53461 atgtcttttt caatccaaat gctgaagtac cctctaaatc agtcccagat aggtcccgta
    53521 atttatgaat cgggatatca gttttaaaat attttaaaat catcgaaagg caagcaacac
    53581 cacaatcttt ttcatcttgt tgctgcacaa aaggaaatga ttttatcact tatctaacac
    53641 aactccttct aaaaaatttt tatagaaaaa ttctcaatat agctttaata cagtgaaaat
    53701 attgtctcat aattccacaa aaactttgaa aacagttctt gaacactaac tttttcattc
    53761 ctgaatcaaa tttattttgg aaattttact attcaagaat aaacttgata agtttcagga
    53821 agatttttac tgttaatcaa atacgtatgt tacagtagca ccgtaaaaaa tattatttaa
    53881 agaagcgtgt ttaaacatgc aaaatgtaaa ggaactaagt attgtggaaa tgcacaaact
    53941 gttggtggag gcaataatgc ttggggaaaa ttggggcaag ttgtaggtgg acttaccaca
    54001 ggggcagtag gtggtgcagg tttaggaaca gcaatttgcg gaccagcttg cggtgttgtt
    54061 ggagggttat atggagctgt cgctggaggt gctgcagctg gctgggatgc tcgaaaaaaa
    54121 taaaaaagga gaataagtag tatgcatatt aaaaacacaa aaacaacatt tatattatct
    54181 tcagaagagt tgaaaaatat tcaaggtggg agtgccgtgg gagttttagg cactactttt
    54241 tctggggcaa cagcaggagt aaaactttgt tcagccggag gaccttatgc aatagctgct
    54301 tgtggtgtag gtggagcttt attaggtgct ggattcagca tgtggaccgg tgcgtaaaca
    54361 attaaaaaat atcaaacctc aagattggtt tgtgtcgatt acgaacatag gtatgttctt
    54421 tatcttttca aaagtttgga atggacagaa ctttttacta aagcttcttg tgctagtttt
    54481 tataattata ttaaattttt atcttttatt aaagtcagat aaaaattctt tggaaatgta
    54541 atggtagaga tatttttaca aaaggacttg cagcgctgta gttggtgctg caggaggacc
    54601 tatttcggcc gttacaggag gtattggtaa tgtacttgtc ggatgtgcat taaagcctgt
    54661 tcctgcaagt taaatttata aaaacaggaa agtaattatc tcaaatccta tcaagtacaa
    54721 tcataggatt gcacttgaca ggacaaattt tttaactaaa aaatgaaaaa cactttctaa
    54781 aaattagtag aatttgccaa atctttcgca tcttccacca tacatttaat tttaattccc
    54841 ctttatggta cttaataaaa acaagaaaag aactattcat ttggcccttt tttggttcca
    54901 gaccatagaa atattcctcc agtaactaat attgctgtta tgcacgtaac taataacagc
    54961 tataaaaatt ggtacaactt taataggatt cagaaaaatt tgcactagtg aaggaatcta
    55021 ttttattaga aaaatgcaat ctccctaaag aaaaaaccac taaacagtgc tttctttcaa
    55081 cttctcctta attttttgtg ctttccctaa agtaaagttt ctggccaact ctgaatcaaa
    55141 atatagtgaa cgttttttaa aatctatttc tttaacgtta aagatattta ctaaacacgc
    55201 tcgactaatt cttgttaaca taggatattt cttttcaagc tcactaattc ttccataaaa
    55261 ttcgtactgc ccatctttag tacacaatga taatctatgt ggtaattttg aagcttctac
    55321 aaaataaatg tcatttatat caaaagtaaa tgtttgagaa cctatggaaa aaacaaatgc
    55381 ttgattcgta acctgttttg ttgcatctat cctttcttgc gctaataaca ataactcaac
    55441 aatctcgttt cgatactcat ctagtgtttg atcttttgtt acaaatccta acgtttcaac
    55501 tcttcttttt attgttacgg gtaacatctc atcatgagta gttgtaaaaa tgatttttgc
    55561 ttgaacatca tattttctga ttacttctgc taattctata ccgttaactt catgatttaa
    55621 atcaatatct aagaaatata ttccttgctt tggtcggaat tgtttgaggt attttttaac
    55681 ttctaacgga ctttgtgttt tcaatactat cttaaatact ttatcgtgaa aaagaatgaa
    55741 attatcaata attcgttcta actgatttaa ttgtataatt tgatcttcac ataatattat
    55801 tggataactc ataaatcctc cttccctcaa aacaacaaaa taacttgagt agtaaattga
    55861 tacggatcgt tttgatagtt cacaaacata ttgggattct ttttattgat ttcctctata
    55921 ctagataaac ctaacccttg atgtcccttt tttgttgtta ttcctttttt cattagagta
    55981 tctatagaga gtagtatctc tctacaacta ttcgatatcg aaatttctat ctgtttatca
    56041 tctcggtaaa tagctagaga cagttctcta tcttgactct ctatagatgc ttcaattgca
    56101 ttatcgagaa taattccaag caccctaata cagtcaaata ttggaacagg aacttcaata
    56161 atagtacttg gacattcgaa tttacaacaa atcttattgt tatttgcttg gtatagcttc
    56221 gctatcaaca aacttttcaa atattcattt tttatatttt ttaaataacg atattcaaac
    56281 ttattggtta gataagaatt agaatagatc tctaattctt ttatttcttt ttccaatatc
    56341 gaatcatggt tttgattagc gatttctttt aaactcagca ataaattttt atagtcatgt
    56401 ctaaatctgg caaatttttc ttgatctttt tccagtgaat cagtatattt ttttagataa
    56461 accaattctt ttcttttcaa ttgctgttca tattgttctc gttgcctaat agttattcta
    56521 ataaataaaa atagaacaac aaacatttga atgattaaaa atattaagac accaaacaca
    56581 aaatgatcaa atacttgata ttgatgagca acataagaaa caaataaacc aattgtaagt
    56641 aaataaatca tgaatatagc agtaagttta gaactggact gttcaacaat cctatttata
    56701 gctaattttc tatataacca aataaacatc agcaaaaaca aagaatcaag cattatctgg
    56761 aatactacat aaccataccc ttttatccct tcaaatgaaa acatatacgt cataaccatg
    56821 gaagtaataa tagatctgaa atcatcaata agcatacata atagtaattt atttaaaagc
    56881 actatattag ttttcttctt ttcctttaat ataaaataac ttccgattat aggtatagct
    56941 gcggaaacat cagtaaataa ttcaacaaaa aaagtgagtg gtatcaataa acatacaaaa
    57001 agatattttc ttttgttaag atcagtatta gtcatataaa ataagagaaa aaagaaaaag
    57061 tttcccacga acattcttaa tagataagct tttgtatcga tagtaatcaa gagatcccct
    57121 cctgatttta ggatatcata aaaaaaattt tagttacact ttttaaataa tgaaaaaaca
    57181 cattccacta aatttgatgc cggttttcct tgaggttttg ttccagcacc tcctttaatt
    57241 tttttaagct cttgatctga acattgttta gcatttagtc tatttttttc ttccattacg
    57301 attcccccta caaactataa atac
//
LOCUS       DAZKCW010000012        55113 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000012 DAZKCW010000000
VERSION     DAZKCW010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.012"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="ACG84Z_000804"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="ACG84Z_000804"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFP9161666.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="ACG84Z_000805"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="ACG84Z_000805"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFP9161667.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="ACG84Z_000806"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="ACG84Z_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFP9161668.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="ACG84Z_000807"
     CDS             complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="ACG84Z_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFP9161669.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="ACG84Z_000808"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="ACG84Z_000808"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFP9161670.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="ACG84Z_000809"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="ACG84Z_000809"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFP9161671.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="ACG84Z_000810"
     CDS             complement(8557..9027)
                     /locus_tag="ACG84Z_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFP9161672.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="ACG84Z_000811"
     CDS             complement(9073..9498)
                     /locus_tag="ACG84Z_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFP9161673.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="ACG84Z_000812"
     CDS             complement(9565..9834)
                     /locus_tag="ACG84Z_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFP9161674.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="ACG84Z_000813"
     CDS             complement(9845..11440)
                     /locus_tag="ACG84Z_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFP9161675.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="ACG84Z_000814"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="ACG84Z_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFP9161676.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVSDQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /gene="pth"
                     /locus_tag="ACG84Z_000815"
     CDS             complement(14993..15553)
                     /gene="pth"
                     /locus_tag="ACG84Z_000815"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFP9161677.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="ACG84Z_000816"
     CDS             15906..16880
                     /locus_tag="ACG84Z_000816"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFP9161678.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="ACG84Z_000817"
     CDS             17050..18450
                     /locus_tag="ACG84Z_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFP9161679.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="ACG84Z_000818"
     CDS             complement(18528..19250)
                     /locus_tag="ACG84Z_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9161680.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="ACG84Z_000819"
     CDS             complement(19329..19835)
                     /locus_tag="ACG84Z_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFP9161681.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="ACG84Z_000820"
     CDS             19958..21757
                     /locus_tag="ACG84Z_000820"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFP9161682.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21825..23399)
                     /locus_tag="ACG84Z_000821"
     CDS             complement(21825..23399)
                     /locus_tag="ACG84Z_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFP9161683.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="ACG84Z_000822"
     CDS             complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="ACG84Z_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFP9161684.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="ACG84Z_000823"
     CDS             complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="ACG84Z_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFP9161685.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25176..25814)
                     /locus_tag="ACG84Z_000824"
     CDS             complement(25176..25814)
                     /locus_tag="ACG84Z_000824"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFP9161686.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25815..26465)
                     /gene="rpe"
                     /locus_tag="ACG84Z_000825"
     CDS             complement(25815..26465)
                     /gene="rpe"
                     /locus_tag="ACG84Z_000825"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFP9161687.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="ACG84Z_000826"
     CDS             complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="ACG84Z_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFP9161688.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27542..29599)
                     /gene="pknB"
                     /locus_tag="ACG84Z_000827"
     CDS             complement(27542..29599)
                     /gene="pknB"
                     /locus_tag="ACG84Z_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFP9161689.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIALSETS
                     ITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVTIALK
                     HFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPARANEE
                     KWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKKKGQK
                     KWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVATKTE
                     EIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAEASLK
                     ELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVTLSSH
                     VGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYINFVV
                     SQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGAGTTI
                     TKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSASTSE
                     SSK"
     gene            complement(29596..30336)
                     /locus_tag="ACG84Z_000828"
     CDS             complement(29596..30336)
                     /locus_tag="ACG84Z_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFP9161690.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30349..31707)
                     /gene="rsmB"
                     /locus_tag="ACG84Z_000829"
     CDS             complement(30349..31707)
                     /gene="rsmB"
                     /locus_tag="ACG84Z_000829"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFP9161691.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31707..32645)
                     /gene="fmt"
                     /locus_tag="ACG84Z_000830"
     CDS             complement(31707..32645)
                     /gene="fmt"
                     /locus_tag="ACG84Z_000830"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFP9161692.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32638..33129)
                     /gene="def"
                     /locus_tag="ACG84Z_000831"
     CDS             complement(32638..33129)
                     /gene="def"
                     /locus_tag="ACG84Z_000831"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFP9161693.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33144..35552)
                     /gene="priA"
                     /locus_tag="ACG84Z_000832"
     CDS             complement(33144..35552)
                     /gene="priA"
                     /locus_tag="ACG84Z_000832"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFP9161694.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35805..36110)
                     /gene="rpoZ"
                     /locus_tag="ACG84Z_000833"
     CDS             complement(35805..36110)
                     /gene="rpoZ"
                     /locus_tag="ACG84Z_000833"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFP9161695.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36115..36729)
                     /gene="gmk"
                     /locus_tag="ACG84Z_000834"
     CDS             complement(36115..36729)
                     /gene="gmk"
                     /locus_tag="ACG84Z_000834"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFP9161696.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37216..37500)
                     /locus_tag="ACG84Z_000835"
     CDS             complement(37216..37500)
                     /locus_tag="ACG84Z_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161697.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37518..38408)
                     /locus_tag="ACG84Z_000836"
     CDS             complement(37518..38408)
                     /locus_tag="ACG84Z_000836"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFP9161698.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38428..38646)
                     /locus_tag="ACG84Z_000837"
     CDS             complement(38428..38646)
                     /locus_tag="ACG84Z_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFP9161699.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38616..40316)
                     /locus_tag="ACG84Z_000838"
     CDS             complement(38616..40316)
                     /locus_tag="ACG84Z_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFP9161700.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40583..41356
                     /locus_tag="ACG84Z_000839"
     CDS             40583..41356
                     /locus_tag="ACG84Z_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161701.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41437..42006)
                     /gene="thiT"
                     /locus_tag="ACG84Z_000840"
     CDS             complement(41437..42006)
                     /gene="thiT"
                     /locus_tag="ACG84Z_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFP9161702.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42072..42174)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42180..43151)
                     /locus_tag="ACG84Z_000841"
     CDS             complement(42180..43151)
                     /locus_tag="ACG84Z_000841"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFP9161703.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43245..44618)
                     /gene="glmU"
                     /locus_tag="ACG84Z_000842"
     CDS             complement(43245..44618)
                     /gene="glmU"
                     /locus_tag="ACG84Z_000842"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFP9161704.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45121..45939)
                     /gene="purR"
                     /locus_tag="ACG84Z_000843"
     CDS             complement(45121..45939)
                     /gene="purR"
                     /locus_tag="ACG84Z_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFP9161705.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46106..46930)
                     /locus_tag="ACG84Z_000844"
     CDS             complement(46106..46930)
                     /locus_tag="ACG84Z_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFP9161706.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46903..47583)
                     /locus_tag="ACG84Z_000845"
     CDS             complement(46903..47583)
                     /locus_tag="ACG84Z_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFP9161707.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47606..48544)
                     /locus_tag="ACG84Z_000846"
     CDS             complement(47606..48544)
                     /locus_tag="ACG84Z_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFP9161708.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48789..49640)
                     /gene="ispE"
                     /locus_tag="ACG84Z_000847"
     CDS             complement(48789..49640)
                     /gene="ispE"
                     /locus_tag="ACG84Z_000847"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFP9161709.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49794..52367)
                     /gene="mprF"
                     /locus_tag="ACG84Z_000848"
     CDS             complement(49794..52367)
                     /gene="mprF"
                     /locus_tag="ACG84Z_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFP9161710.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52508..53314
                     /gene="proC"
                     /locus_tag="ACG84Z_000849"
     CDS             52508..53314
                     /gene="proC"
                     /locus_tag="ACG84Z_000849"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFP9161711.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53393..54949)
                     /gene="rny"
                     /locus_tag="ACG84Z_000850"
     CDS             complement(53393..54949)
                     /gene="rny"
                     /locus_tag="ACG84Z_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFP9161712.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
BASE COUNT        15215 a        11963 c         9869 g        18066 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta ccataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttcccctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg gaatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctcctccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgacacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta cacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagcttttac atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggttga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ctgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttgattaatc attcttacat gctgacagca
    21841 aagtcagggg caaaccattg aactgaacca acttttacgc tttcgcctgg ttgaggagca
    21901 tggatatatt gtcctccgcc taaagcaatc gctacgtggt aagttccgcc ttgtgacccc
    21961 cagaataaca agtctccagc ttttgcttga gaaactgaaa tttttgttcc agctgattct
    22021 tgaggaactg tccaaccacc gatgtcacga ccagttactt gcatgtaaac atagcgtgtg
    22081 aaccctgagc agtcaaagcc acttggatct ttaccgcccc aaacatatgg agtaccaata
    22141 tatttgtaag cttctgctac gattgctgca ccattcacac ttccagaagg agctggagca
    22201 ggtgttacag gttttggttg ttcaggtgtt ggtgttggcg ttggagccgg agtactactt
    22261 cctgtgccgt ttcctgtatc aacactttga tctgttgatg gtgttgtagg cgcaggtgtt
    22321 gttgattctt ctgttgttga agattcaggc actgttgttg attcttctgt tgctgaagat
    22381 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcgctgttgt tgattcttct
    22441 gttgctgaag attcaggcgc tgttgattct tctgttgaag attcaggtgt tgttgattct
    22501 tctgttgctg aagattgtgt agctgatgat gattcttcag tcattgaaga ttgtgtagct
    22561 gatgattctt ctgttgctga gctttgtgca gtagatgaag cttgagtagc ttgtgcttca
    22621 gcctctgctt gttcgcgtgc ttctttttca gctttttctt gtgcagcttg ttgacgagct
    22681 tgttctgcta gacgttgttg ttcacgaata cgagcttgct ctgcttcagc ttctgctttt
    22741 tgacggttca agtcagcttt cttgtcttca gcagttgctt gttcagcagc taatgaagtt
    22801 ttcagtacgt tcaaatcagc ttgtttagat aaaagatcgc ctttttgaga ttccaaagca
    22861 gcttggtttt cagctaattc ttttagttta gcatcgtttt cagctttttt gtcttctaca
    22921 gcttttttat cttgtttttg ttgttccatc aagtcgttgt ttgcttttac catcgttgtc
    22981 attgcttgaa cgcgtccaat agcatctgct aatgaatcag cattcaatac agcatcgatg
    23041 tagtttgagc ttgtgttgct tacttgtgct tcgcgtgctt gtttttggat tgtatcttca
    23101 cgtttttcaa tacgttcttg taaatctgca atgtctttta ctaattgtgc agattcttga
    23161 cgcaatgtat cttgttttgc taataggtct tgtgcttgtg tgttgatttc agaaacttgg
    23221 ctttctaagg catcgatttg tgattgtgca tctgcttgtt gatttttcaa gtctgcaatc
    23281 ttttgatctt gctgttgtat ctgagaatca aaatcgtccg ccgcggcagc gatcggtgat
    23341 gctacggcag tcaaggtcat tgaacatacc attactgctg atattaaact ctttttcact
    23401 cttcattcct ccgactggct taatttaata aatatctaaa tatatttaag tctttcttaa
    23461 cgatataaaa attgtaccat agcagtgtgt caacgatata atagttatgt tacaaaaatg
    23521 tttcaaaaca acttttaaaa atgacaaaac tgttcgtttc agaaaatgat catgaaaaag
    23581 ccgcgttaag tctagcattt cttaagataa caacgattct ttttcgcttt cgacctaaaa
    23641 ataaaaaaag aaattattca tcactgaata atttcttaaa gggaaaaatg aataatacaa
    23701 atataatcat gttcaacagc agtgtaggtc ctaaaaacct tgtaataaaa tacgtgttat
    23761 ttactactgc taatttaaaa atcaactgga ccaccatcgt aaacaattca taacccgtga
    23821 caaagatgat catactgaaa aattcagtaa agatgttgac atggataacg tctttcatta
    23881 catacatcaa ccatacaatt aaagggagag ctactgcata gataccgata acgccaatat
    23941 agtaagcgtc atagatagcc ccgagaacaa tcgtggtaat cagtaaataa cgtttttcaa
    24001 acgccatact gcaacataat aatgccaata tcagaaagtg ggcatttgac atataggtgc
    24061 ctttcgacca ctcccctagc attcttgtta aatgaccatc tatcaacatc aaaaagaaca
    24121 aaacgattgg cagatagtac ttcattgttt ctttcttcaa catggactaa tcctccgcta
    24181 gccgttggac aatcgtcaca actgacacgt catacatttc tgcataaggt ttcacataaa
    24241 cttcccgatc cagcccataa ctatctggtt tcgttttaat aaccgtaccg atcggcaagt
    24301 tagctggaga attccctcca agaccggatg tctggacaac atccccttct ttgatatccg
    24361 tatcaccagt taattgggtc accactaagg catggagctt ttcatcatag tttttaagca
    24421 aaccaaacgc ttcgccatta gccgaagata cccgtactgg aaaatgattg gagctttcat
    24481 tagaggatga cagtaattcg attttagacg aagccgtatt gacctcgatc actcggccaa
    24541 tcaatccttt ttgcgacatg actgccatat ttgcttcgat accgtcttta gaacccttgt
    24601 ctacgatcag catgtcctgc caactgtcag gcgaacgagt aatgacattt gccgttactt
    24661 tttcgtaact agtcagcgtc tgattcaact caagttcttt tttcaacgct tcgatttctc
    24721 tctcgtaatt cttgttttgc tgtgaaacgt catcatagct atcgattttt tcttttagcc
    24781 gctcattttc ggcataagtt gaaaaaagat tatggacaga atctactcca tttcgtaccc
    24841 accgtactgg ggcagagatt gttttatcaa ccattgcaac actgtcatta acgatggatt
    24901 ggaagaaatt gggctttcct tcattcgctc gctgcgcagc ggtcacactt agtatcgtca
    24961 ccacgatgat aacaataacc aaggtaataa taatattttt attaggattg aacttcttca
    25021 caaagacacc tcgaattaat tagactcttg tgttcaattt tatcactaaa tgccgtgaaa
    25081 caaaaggtaa gttgctcctc ttaagctttt ttttagcaaa taatagattc tgtcattttt
    25141 agcctgaaag acaaattttt ttatttgttt atggatcaat ctttgctttg aataactgca
    25201 atcataccat ctgaaaaaga aaattctgcg gtatctgaaa gaaattcgtt acttgcataa
    25261 gatgtcggat attctacttc tttattttcc aatacatact tgctgccttt taatgtaaga
    25321 ttcgagacgg gagtcaagca gcaataagct aaatacttca tatctggtat ctgtcttact
    25381 atatgctctc caggcaaata ataagacaaa taattttgac aatctctgat aataagctga
    25441 tgggcaaagg gtttgaagcg aggttccata cctaaccaga gattggctaa aagatgatcc
    25501 aatcttccgc ccgtagctcc aatcaaagtg acttccgctt gcgggtaacg ttcaaatgtt
    25561 tttaagatac ctaactgtgt atctgtatcg tctttttctg caggggaacg ggtatactct
    25621 ttggcttttg caaatacttc cttctgctct tcgttcgaca atgaatcaaa atcacccact
    25681 gccagatcta ctgggtagcc tgcttgaagc aggtacagcg caccacggtc tatcccgaca
    25741 taggcatcgt atttggacag cagagactgc ggccagtttt gcggattacc tccagcagct
    25801 aataaaattt tcatttagtc taatgcctct tttaatcgtt cgatttgtcc gactggattt
    25861 tcggctccat agatatatga tcctgcaacg aagacatccg cccctgcatc tttacagatt
    25921 tttgctgttt ctggaacgat tccgccatct acttcgattg cataagtcca attgttctct
    25981 ctacgtagat cagcgagttc cgtaattttt tctactgttt cttcaataaa gctttgtccg
    26041 ccgaacccag gattgacagt catgactagt acttgatcag ccaaaggcaa aacatgtttg
    26101 atcatggaga ctggtgttcc tggattgata actactccag ctttaactcc taagcttttt
    26161 gtcatttgaa gtgcccgatg aatatgagga gttgcttcga cgtggacagt aatgatatct
    26221 gctccagctt ttgcaaatgc tggaatgtag ttttctggat caacgatcat cagatggacg
    26281 tctaacggta atttagtaac aggacggatt gcctgaacaa tatttggccc taatgtgata
    26341 tttgggacaa atcggccatc cattacatct acgtggatgt aatctgcgcc tcctttttcc
    26401 actaactcaa tgtctctttg taaattggca aaatctgcac tcaaaatgga tggtgctatc
    26461 ttcattcttg tttcctccta ttttcgttta ccttcttttt ttgcatacat tggttttctt
    26521 ttttcgattt cttgtaagaa ttgcaaataa ttgtcgtaac gtgtctgtgc gataccacct
    26581 gtttctactc tatgttttac ttcgcagcca ggttctttag catgcatgca ctctctaaat
    26641 ttgcaatgga cagaagcttc tacaaattca ggaaattgtc tcggcagttc tcctgcttca
    26701 attgtcaaaa agtcaatcga gctaaatcct ggtgtatctg ctactaaccc gccatagata
    26761 ggaatcagtt ccacatgacg tgttgtatgc cgtcctcttc caagtgcatc agaaatctct
    26821 cctgttgcta aattcagttc cggtgatatt tgattcagta gcgtcgattt tcctgctcca
    26881 gactgaccca taaagaccga tagccgttct gggaagtaac ggatcagttc tgtcgtatca
    26941 cccgtatgat tgggtacaat caccggatag cctattttag tataggtttg cttgatctct
    27001 tcgatttttt ctgggtcgtc tgacaagtcg gtctttgtca aaaaaataat cggttcgatc
    27061 gactcgtatt ccaaggtaac tagaaagcgg tcaagtagat tataagaaaa tgcaggctct
    27121 acgatacttg tgacaatgat tccaagatca acatttgtga ctggtgggcg aactaattga
    27181 ttttttctcg gcaagatttc cagaagatag ccgtctgttt gattttcact ctcaaagatc
    27241 acctgatctc cgacaagcgg cgtgattttc cgattccgga aatttcctct tcctcttgtt
    27301 tgataggtct ctccgtttgc gtatacatag taaaaaccgc tgattgcttt tctgatttgt
    27361 cctttgataa gtgccacctc cgtttttgtt tattttacca tacgaagagg aaagtaggtg
    27421 ttattccatg caaacttctc aaagtatatg gcttgaaaat tgatcaaaag agatagaaac
    27481 acaaaaaaga gaatgcaaca aatcaatgtc gcattccctt ctgatatatt ttattcagca
    27541 cttattttga actttctgag gtgctagctg atgaacttgt ggagctggaa gattcttctt
    27601 ttgaagagtt gcttgtgcta ctggagctac ttgagctgct agaactgtct gaagagtctt
    27661 tttcagaact agaagacgct ggatctggtc ctttagagta aattacgttc acaaccattc
    27721 ctttggtaat tgtcgttcct gcccctggta ctgtacgaat cactttatct ttatccaccg
    27781 tgtttgaata ttcggaagtc tcatgcccga tatattctgc accgacacta gctaaataac
    27841 tttgtgcttc gctttttgta tagccggaga tatcattcaa tttaggctct gttccttggc
    27901 ttacgacaaa attgatgtaa gtttcttctg ctacaacttc acccgaggct ggatcctgac
    27961 tgatgatcga acctgatggt acagtgtcgc tatagtcata agtagcacta atattattga
    28021 tattgaatcc ttgtgtaaca agccaattac gaacagtttc gtagttttct cctacatgac
    28081 tactcaaagt cactgtttct ggtcctttgc tgactgtgaa agtaatcgtg tctgttttag
    28141 gatcgacttc tgtatcttct gatggagatt gcgaaatgat cattccgctt tctacctctg
    28201 aactgaattc ctcttctttt tgaatcaagt cagcagaaaa ccctaattct ttcaaacttg
    28261 cttcggcatc ttcataactt ttaccactgt aatcatctaa tttgattttt ttcgtgccgc
    28321 tactaatata cagagtgact tcgcgttttt gcttgactgt cgttcccgct gccgggtctg
    28381 tcttcactac attaccttct tcgattttgt catctgcaat ttcttctgtt tttgttgcta
    28441 cttctaattt cgcttttgcg agtgtttctc tagcagaagc ttcagaaaga tcagaaacat
    28501 caggaacaac aacttctcct cgcccgccag aagcaaagaa tacagctgtt ccgattccta
    28561 aaacagcaag aatagctaat aggatcagcc accatttttt ctgtcctttc tttttaggat
    28621 caggcagaac ttcttcctcc tctggtaagg tttcgttttc tggcttgtct tttggcagag
    28681 gcatagattt gaatgaatca ggcattggtg catcttccgt aaggggtgtg ataacttttg
    28741 tttcattatc catcacatga ggctgccatt tttcttcgtt tgcacgagct ggtgataata
    28801 ctgtagaaag atcatcagac atttcctcgg ctgacttata acggtctgca ggttctttag
    28861 ccgttgcccg taaaatcacg ttttccagtg cttgtggcac atttggatca agtgctttta
    28921 tagatggaag atcatcttga aaatgtttta aagcaattgt tacagcagat tcaccatcaa
    28981 acggtacgct acccgtcaac atctcataaa ggatgatccc taaagcataa atatctgact
    29041 gcttcgttgc catacttcct ctggcctgct caggggacag ataatgaaca gatcctagca
    29101 tcgtattcgt ctgcgtgatc gatgtttcag ataaagcgat agcaatcccg aaatccgtga
    29161 tttttacaac accttcatta tcgatcagta cgttttgggg tttcaaatct cggtggatga
    29221 tttgatggtt atgagctaaa gaaatagcag aaaggatctg ctgcataata ttataaggaa
    29281 caggataatg tgtttggata tatcgtttca agtccattcc tttgacgtat tccatcacca
    29341 gatactgcat gttgtcttct tcaccaacat cgtaaacact aacaatgttt ggatgaacga
    29401 gttctgttgc tgctaaagct tctctctgaa atcgtcgaat cgcagtctgg tcattttgaa
    29461 agtcaaatcg taagacttta actgctacat cacgatccaa gattaaatcg tgcgccaaaa
    29521 atacatttgc cataccaccg ctaccgatat ttccagtgat ttgataacgg ccatttaatt
    29581 ttttgcccaa ctcgatcata cactgtcctc cttatattcg ataagaagaa cggtgatatt
    29641 atccgctccg cctgcttcat tggcacgatc aatcagctca gttactttat gagacaatgg
    29701 gccttcttga ttgatgatcg ttcctatttc ttcttcagac agcatgttcg tcaagccatc
    29761 tgaacataac agcagtcgat cttttagttg ccaaagatga gtagaaacat ctacttcgac
    29821 tgttccaggc atgccgacag aacgtgttaa aatatttttc cttggatggt tcactgccat
    29881 ttcttcgctg atttctcctg atttgactag ttcattgact aaagaatgat cctccgtcaa
    29941 ttgcatgatt ttatcttcac gaatcaaata agctctgcta tccccaacat tggcaatcgt
    30001 gaaccagtca tctgacagag cggccgctac gattgttgtt cccataccgt tatattccgg
    30061 ctgttcttgt ccacgctgat aaatcagcat attttcttct tgaatcgatt gaatgaacca
    30121 ttgggcgatt ttttcatcgt caacagcttc ttgtttttcc caagcttcgc ctagattcgt
    30181 taccgccatc tgactggcaa tgtctccggc acgatgacca cccatcccgt ctgctaatac
    30241 agcaagcttg agacctgaac ggctggtaaa tacactggca tagtcttgat ttgtgttacg
    30301 tcgtcttcct acatctgatt gatattcaat ctgcattttt tcacctcatt actttttgcg
    30361 caaacaacaa atgaaaaatc catctgtgta aaactgatgc ggatacaaag tcaacatttt
    30421 ctcttcgatt gatgattgta gcataggatt ggtcaaaaca tcaatcctct caaaatcagg
    30481 gtgtctttcc aagaaagcag aaacaacgtc ttggttttct tcttttaaga tcgtacaagt
    30541 gctataagtc agaataccgg aagactttaa agttggtgcg cagctttcta aaatttccaa
    30601 ttggattttt ggtaaattcg ctaattcatc cggctgtttt ttataacgaa tatctggttt
    30661 tcgccgaagc agcccaagac ctgaacaagg cgcgtctact aaaatccgat caaactgctc
    30721 tgcttcgaac tgtttactga cttctctagc atccatcttt tgagcgtaga cagcagaaga
    30781 gacacctaga cgtgctgcat tatcttcaat gagtttgact ttgtgttcgt gtacatctaa
    30841 agcgaccact tctccaccgc atgacggatc taaaaaagaa gcaatatgcg tcgtcttacc
    30901 tccgggtgct gcacaggcat ctaagacatg atgttcaggc tcgatttgca tagacggcgc
    30961 tacaagcatc gaactttcat cttggatcgt catgacgcca tcgtggaaca atgagctaga
    31021 agctaaatgc ccttttttcg ctactatacc gtatggactg acttggcttt tttcagctgt
    31081 gatctcttct tcttgcaaaa cagtgatggc ctgatctctg gaaagtcggc gtgtatctac
    31141 tcgggcacta gcatggctag gctgatatag cgataaaccg agcttttcag tttcttcgta
    31201 tccgatttga tccaccagtc gtttcgtcat ccatagaggc aggctgattt tgacagaaag
    31261 tctttcgata ggatcagcaa tgccttgcag atctggtgct ccttgacgct gataattcct
    31321 caagacacca tttacaaatt tccctgtccc aggatttcct tttacttttg cgatttcgac
    31381 cgcctcgttt aaaatagcat gtgcagggac tttatctaaa aattctaatt ggtatacaga
    31441 aagataaaga agcatcttga cccagtcatc cacttttttt gctttagcga tcaatggtgc
    31501 aacgtaaaat tccaatagtc gctgatggct aatcgtacca tagatcaatt ctgtaaataa
    31561 acccacatct ttttgattta gctcgctttg tttgatcatc tcattcaaca aaagattcga
    31621 gtaggcgcca cccttgttca ctcgctctaa tgtcagtaat gccatatatc gtactgattt
    31681 tttcattttt ttagggattt ttttcattat ttcacctgct gaccaatctg aacttgctga
    31741 ccgcttccgt taaggaaatc atgtacggcc tgttttcctt taccagctgg ctgtaattca
    31801 ttgatggcta agacggtctg tttaccgcaa gcaatccata gatttttttt gtctttccgg
    31861 atgatcgtac caggtgcttt gtctgtagtt tctgccaata cttcaaccga taataatttc
    31921 cagcgtatgc cctcataggt cgtgaatgca attggccaag gacgcattcc gcgtacttgg
    31981 ttgtcaattt cttctgcagt tttatgccaa tcgattgctt cttgttcccg tgtgatgttt
    32041 ggcgaaaaag ttgcttctga ctcgtcttga ggtactggtt tttgtccatc caaaatattg
    32101 ggcaatgttt ctagcaatag ctttcttcct aaaaggctaa gcttttcaaa catcgtccct
    32161 acatcatctt gtttagtgat tggtatgctt tcttgcgcat agattccgcc tgcatccatt
    32221 tttttgatca tttccatgat cgttacacca gtttctttct ccccattcat gatggcataa
    32281 tgaacaggcg cacctccccg atatttagga agtaaagaag catggacatt gattgcccct
    32341 aattttggta cttgcaataa cttttcaggc aagaattggc caaatgccgc agtgacgatc
    32401 acatcaggca ccaattcaat gatttcttcc atttctggcg aaccggagat tttctctggc
    32461 tgcagcacac ggataccgtg cttcagagcc gcttttttta ccggtgtcgg cgtaattact
    32521 cgtttccgcc caactggacg gtcgggctgt gttaccactg cctggatctc gtaacctgat
    32581 tctatcagcc cttcaagaat cggcacagaa aaagcaggtg tgcccataaa tactagctta
    32641 gtcatcaaga tgttcctcca tatattcttc aagttcttct tccgggatct gctgtatcat
    32701 tttctcaatg aacaagatac cgtctaagtg atcgatttca tgctggaagg cacgggctaa
    32761 atagccaaaa gccgtcactt ctatctcttc tccgtctcga tcataataac gcacggtcac
    32821 ttcatctgct cgcttgaccg ttccatagac atgcggaata ctgagacaac cttctacgtc
    32881 aaggctttca ccttttgctt cgatgatttc tgggttaatc agttcaaatt tctcgccttc
    32941 atctacttcg atcacagcaa ttctcttgtt ttgtcctact tgaggagcag cgatccctat
    33001 tccgtcattc gcaatcattg tctcatataa attgtctaat aaagcgattg tctcgtccgt
    33061 gattacatcg attggctgag cagttctttt taatttatca ttagggtgga tcaatatagg
    33121 atagcgcata atttggccct ttcttaaata aagtttaatg gttcgttgtc aattgccaca
    33181 aaaagacctt gtcgctgttc tttctggctt ccattcaaaa tttcatccaa aacatgagga
    33241 agattcggtt catgtttata tttgatgatt agttgataat aatatcggtt tttcactctc
    33301 aaaatcatgc tgggcgttgg ccctaatagc aagctttgag ggcttaacac ttcttttagc
    33361 tgattggcaa tctgaaagat tttctttgcc gctacttgtt cttcaggatg gctggcggtt
    33421 attttcacag taaagtaata aggaggatag cctccacgat gccgtacatg catttcctgc
    33481 tgataaaact gctcataatt ttgtttttta gccaattcta tggcgtaatg ttgaggattg
    33541 aatgtttgga tcacgacttc gcctgctttt tccgctcgcc ctgctcgtcc tgaaacttgg
    33601 gtaagcaatt ggaatgtatg ctcactagaa cgaaaatccg gtaaattcag ggaggtatca
    33661 gcattcaaca ccccaactaa tgtcacttct ggaaagtcca aacctttagc aatcatttgt
    33721 gtccctaata atatatctgc ttcttttgca ccgaattttt gtaaaatctg ttcgtgtgcc
    33781 ccttttcttc gagtggtatc tacatccata cgcaaaatcc tagcttgcgg ataaagttct
    33841 cggagttcct cttctacttt ttgagtacct gttccatagt agcggatttt attgccgcca
    33901 caattaggac agcgattggg aataggttct tcatgtccgc aataatggca gcgcattgaa
    33961 cgtgtatcca tatgcagtgt aagagagata tcgcaattag gacatggaag aacaaatcca
    34021 cagtccctac acatcacaaa agacgaatat cctcgacgat tgagcagtag gacagtttgt
    34081 tcttttttgt ctaatcgatt ttgtattttt tcctgcaaat tagcagaaaa agtagaggtc
    34141 cgatgattct gaaactcttc acgcatatct acgatctcaa tagctggaag ctgtgcagct
    34201 gctttggctc ggtggtttaa ctgcaataac tgataaacgc ctttttgagc tcgtgctctt
    34261 gattctaaag agggcgtcgc gcttcctaga actattgggc aatgatgata tttactgcgc
    34321 caaattgcta gatctctcgc atgataacgc ggtgtctcat cttgtttgta acttgattca
    34381 tgttcttcat cgataatgat cagcccgata tttttcagcg gggcaaaaat agcagatcgt
    34441 gcgcctacta ctacttgcgc ttcttcccgc tcaatcttgc gccattcatc atatttttca
    34501 ccttgggaaa gtccgctatg taagaccgca actgattctc cgaagcgtcc tttgaatcgc
    34561 tcgaccattt gcggagtcaa tgcgatttca ggcactaaca taatagccgt tttattttct
    34621 gacaaaacat cagcgattgc ctgaagatat acttctgttt tcccgctgcc agtgattccc
    34681 tccagcaaaa agacctgatc tttttgctgc tgacctgctg tgatgatttg ttcgacagca
    34741 tttttttgtt ctgcattcag ttccaatgcc gtcgtttggt caaatactcg gtctttataa
    34801 gggtcgcgat aacgttctga ttctataaac tccagccagc ccttttcttt tccttgattc
    34861 aagacagcag tactgattcc tttatttttg aaataagcaa ttggttcttc ttggctcagt
    34921 tcagataaac acaaaagaag ttctttttgt ttcttggcat tttgccgtaa ttttgcccat
    34981 tcttcttcga tttgcttttc agttaacaaa gaacggacca aacgaatcgt ttttacttta
    35041 tttcgtgtat ggacttcata tttgatatct actaattgct cttggcgcca gcgaatcaat
    35101 tgagaaaggc tgccttcttc ttctgcttcc ttccaggaaa tcacttctcg ctgatcaaac
    35161 aatacctgaa cttctggtgt gtctgccaaa ggatagatca atttatcata ttctgctttc
    35221 atcacactcg gaagcatcgt ttgtagacaa gtgattttga atgcgtaagt aatttttttc
    35281 atataatcag ctaatgaaag taattcttca ttgaccaccg gagcaaggtc tagcaaacga
    35341 ataactgcct tcaaagatgg attagctgat tcttctgatt tttggatagc cataacaaat
    35401 ccttggacat gacgattgcc attaccaaaa gggacttcta ctcgcatccc gacttgcaaa
    35461 gctgtttcca tttcagaggg aaccaaataa gtgaatggct gatcggtctg catagtaggt
    35521 acgtccacaa tgacttcagc tgttaatgtc atggttcgtt tcctcctttt tttgtctttt
    35581 cttatcaagc gacaaaaagt tccttgccta ttttactaga gatcgatgga tttgtcttat
    35641 cttctgccaa atcctaacaa aaaattaaca gcagataaga aaaaaaagaa ctgtgtcaaa
    35701 aagttcagac acagcctttt ctaccagaca ataagtggcg aatgtttgaa aaggaaacag
    35761 ctgggtttgc ttttcttttt agatgttcgc tctatttttc tttattacat tttttgctct
    35821 tcacggatac gtgattccaa ttcgtgttgt tcacgctctt tttgtgcttg acgttcctct
    35881 tcttccatct tcaaacgttc acgttttaat tcaggatgtg gatcattgac tacatttcct
    35941 gcatcgattt cttctaaagc ttgaccgacg ctttttactg aatcaaaaga atctagagta
    36001 ggctgtgcac ttgcatccaa ttcatgcgcg cgtttacttg ctaaaatcac tagagaatat
    36061 tttgaattta cacgatctaa tagtgagtca attgaaggtt ttaacatcat aagactacat
    36121 ctcctttaac attttaatat atttaccgat tacgcgatct actcgaaaat gttcactggc
    36181 aataatgttt ttgattcgtt caactgctag cggcacttca tcatttacaa cagcatagtc
    36241 gtaaagagcc atcatttcga tttcttcttt tgcaactttc attcgttttt cgattacttc
    36301 atctgcatct gttcctcggc ctacgatccg tgattttaat tccgctaaat ctggcggagt
    36361 caaaaagatg aatacaccat cgggcacttt ttctttgact tgttttgctc cttggacttc
    36421 aatctccaag aaaacatctt ttccttcatc caatgtcttg ttgacatatg acaaaggagt
    36481 tccataataa ttcccgacat attctgcgta ttccagcatc tctccagctt cgatcattga
    36541 ttcaaactct tctttgcttc ggaagaaata atcaacgcct tcgacctccc cttcacgcat
    36601 tttacgggta gtcattgaga tcgaatactg aaaatcatta tcctcactct caaaaattgc
    36661 ttttcgtact gtgccttttc ctacaccgga tggaccagac aacacgatta ataatccacg
    36721 ctctgacatg acgacgtcct ttcaactagt ctttttgtac ttatcgttta ttttgcactt
    36781 tttttctgca actttcaagg ttatctttaa ttatagctag aaattggtaa aaaagctacc
    36841 ctgtaccaag aggtcgtaaa aaagctgtcc tgcatcaagt aataagaaca gccaaacata
    36901 aacagcttct catgtttttc gtttggttgg ggttattatc gcagatgcaa gcttttgaac
    36961 gccgtgtata agaggtcgtg aagaagccga ttagtttcga gtatgaagaa aaattttgtg
    37021 aaaatagttt ctcacatttt tgcataaatt tggcttaata ccgagaaaat ggtttttgaa
    37081 catcacttat tcaaaataaa aaaagattgt gacacgaatt ttgtcacaac ctttaaatgt
    37141 attcctagag caaagaagct aagcgaagaa atccaattct gtttatttat tgtatttctt
    37201 tgttcagcat ccttgctaaa agcccatatt ggacaaagta ttcactacac ccatgatctc
    37261 atcttttcga gaacgtgctt tttctgtcgg atcttctacc tcttctgtgt caattcgaac
    37321 aataaatttc cgattcatcg tcacgtaagc accgtcgttg atcaaaataa acagttcgtt
    37381 ctcattatag tctgcacagg catctttcca tacgtcaaag ccgttttttt cagaagggat
    37441 atcccgttta accacagttt ttccacttaa ttcgtggaac gttacgtcat aatatttcat
    37501 tatctctacc tctttcgtca ttcaatattt tgtacttgtt ctctgatttt ttctaagatc
    37561 gtcttagact ggacgacttg atttttaatt tcgattgcat ttgatttgga accgatcgtg
    37621 ttgatttccc gattcatttc ttggatcagg aaatctaatt cccgacctac aggacattgt
    37681 gcttcgataa gttcatctag tttttgtaca tggatcgcca gacgatccag ttcctcgtga
    37741 atatctccgc gttccaacaa gatggctagc tccgtcaaca accgttgctc atcgactttc
    37801 gctccaagaa attcctccag ctttttttga taccttattt gaaattcctt ttcatagatt
    37861 tctacaaaac tatcgagttt ttttagtact tctttgaatt cttcagtatt ctttttcaac
    37921 actaaagcta aagcttgacc ttctttttct cgactcgcct caatagaatc aagtgcgctt
    37981 ttcaatgtat ctagagctaa ctgtgccaat tcttccatgc tctcttccgg tttttcttct
    38041 accgttacga agttttcgtc cagcacgaag cgttccgcca tccgactaat tgacacttga
    38101 ttttgactac cgtatcgttg ttgaattccg tctgtcaatt gagtgataag tgaatcaatc
    38161 aattcccagt tgatgacgat ctgtttttcg tttttgccaa tataagctag attcacaaat
    38221 acttcgattc gaccgcggct taactgctgt ttaataagct gacgaaaatc gttttcaaca
    38281 aagttcagga ttttaggact tcgtatttga acatctagaa aacgctggtt gacacttttt
    38341 atttcaatat ctaactgata cgcttttgtt tcgcggatgg ctttgccaaa accagtcata
    38401 cttttcattc gacagggtcc ttcctcatta catattttct attgcttttt gcagttgttc
    38461 aaactcttcg ttcgtcaatg tcaggccttt ccccattttt tcatggtctg gcgcccaatc
    38521 tcgaagatcg aattttggcg ggcgaccatt ccagctgact aggttcagtt ctttacgcca
    38581 ccccttgttg ttttctgaca atatagcgat ttcttctacg atttcatatg aaaattcttg
    38641 tgccatggtt gttcctcctt gagataatat aaatatagga tcagtaatgt gtcaactggt
    38701 tgcttaagca attcatgctg caaacgatcc ttgcgttttc cttgtagcag ataatcaaaa
    38761 taaacagttt tcgtgcgctc attttgtatt ttttgctggt attttcgata ccttcgccat
    38821 tcttcagtac ttaattgacc aatttgtgcc aataaatcat ccggcatact ttttatatct
    38881 tgttggcaga tcatttgaat catcatgtct acttgataga tttcattggg cagtaaaaaa
    38941 tgtttttttg ctaaaagttc tagcatcgcc aatccgcatg tctctggtac gaccctgttc
    39001 ttatataaat tacgcagttt ttgccaaaat tttatgcttt tgaaaaaaga taattctaac
    39061 tgaatttctt ttgttaagta agacaaaaat cctcgccagt atgttcttgc aggtttaaca
    39121 gaatgaaatg tataccagtt cccatagtaa tagcctaatc gttttttcat ttccagatag
    39181 cctaattgta aatttaattg gttcctttgg ctatcaaaaa gcagaaagct gcctagtgtc
    39241 cacaatgttt gacatttcca atggataaaa atgtctggca tacgaatttt tttcgctggg
    39301 cctggccctt gcacatctac gacaaatgcc tctgttgctc ctttgttaat cgcaatatca
    39361 ataggtattt tgttgcgata cccaccgtct gcatatttat tttttccgat ctttcgataa
    39421 gccatagcgg gataaaatga agcagaggcg agtatccaat ctggtatttc ttctgttttt
    39481 gtctgttgga tatcagtcac tacttccgct agttctggca gtttagtaga caccgtatat
    39541 aaacgtattt tgggattatg tttgagtaag gacaaatcca aattgtcttt gaccatcttt
    39601 tccaatggag cagaagaaac cccgccttca attagtgctg ttttcgtcat ttggcgtctt
    39661 tctcgataga agcgttcacg aaggtcttca actgcagcca tttctggtaa cgcaagcact
    39721 tgtcttgtcg acagcttttt ccataaattc acagcttttt tcatatctcc ttgtaaaatc
    39781 aatgcgccgt tcaacgcacc taccgaggta cctgtgataa tctcaaagtt gatatcatgt
    39841 tccttcagcg cctgccacac accaatctga taagcaccgt gcgctcctcc tccacctaaa
    39901 acaagtgctg tatgatagac cagcttttta tttaattgtg tggttccttg atagccgttt
    39961 ttatgaaaaa tacgcaacca ttcttctgat agaggagatt gaaataaaaa acaacagttt
    40021 tctttaataa aaaaacgagc gcaagcttcc atataccgaa aaaatttttt ccattcaaaa
    40081 gtttcacctt caatcaacag attattaaaa ataacatctc ctctactttt agcaatagta
    40141 aaatagacgg tatatttttt cgatactgct ttaaaagcac attgcttttt tgcagaacgc
    40201 caaaaagcgt ctctactttc ttgatgactt tgaaaaaatg gaaggggttg ttttgcttgc
    40261 tggataggcg aatacagcga cattttctgt gaaaagtaaa ctttttttat ctccatcgcg
    40321 ctctcctttt tcttcaagta taccagtacg tcataaaaag gtcatgagtc tcgtattcga
    40381 ctttgtagat tccataagaa aacaattcat aaaacctcct ttaaataaaa aaatacaaaa
    40441 atcacaaaaa ttaattgaaa atgagagtgt tttcaatgaa aacgtgattt tgtaatggaa
    40501 ttttaaaata aaagaaacaa gcttttttaa tgcaaatgtt gtaaaataaa agagattaag
    40561 aggaaataag aggaggaaca tgatgactga gtcagtttat gtacatattg ataccacaag
    40621 taatgctgtt ttaacaaaag ggctgactgc tactgacttt gcaaacagta tcgtgcattt
    40681 tcctcaaaac ttgctcttgc ttgatccatc tgcttctgct ggagaatatg aatcccatac
    40741 agggctgaaa gtaatccgtg gtacagaaaa tattcagcgt ttcttttcct cttctcgtaa
    40801 caggcgtgga ttcgatgaat tgaagtggat cgactttact gatttaacga tgctgaaaga
    40861 attgacacct ttagaaattt cagaattatt atattttggt catatgaaaa cacatcttca
    40921 ttcgccgttt ttttataaac tacagaataa ttttgtatac ttcgatctta atgatcagct
    40981 gaatcggatt tattatcgct atttagatga attttatagg atttttgcta gtaaattaag
    41041 ttcgatcttg tcagataaga tcaatgtaaa aaaatctttt ttcaaaaaag aaacacctgt
    41101 tgaaaaaatc agtgtggaat tattgaaaga aatgcgtaat ttgatgcagg aagggatcat
    41161 tttttctttt gatcaagttg gtttgatcga tggtaaatat cgtatcccaa tctatgtgat
    41221 tgaagattat atttggaaat taaaaggcac ccggtatcga gaagaggaaa tcatcgctac
    41281 tttaatctac tctgtcaccg atcgacactg gcaattggta gaagatgccg atctttctta
    41341 tctgccattg aagtagatct atttcttatc aaaaaataaa aaggaaacaa gaaactagga
    41401 catgattctg tctcaagttt cttgcttctt ttttatttac agctcctgtc gtttatctgg
    41461 cacaaaaatc gaaggagtcg tttgttggat ccctaataaa acgatgatcg ttacaatagc
    41521 tgtactcaac ccgctggcac cattcattac gaaagaaaag agccaaggat tcatccccca
    41581 tagtgcatac gctccccaga aaaccactcc tgcaataaaa tgccaaaaat atctggaaag
    41641 tgcgccaatc aatgcaccaa acacgatgct ttttctaatt tgtttcgtat tatcgtctac
    41701 atagcctttt tggacatttg aagccatgag ccctgctgcg cctgcaaaag tataggcaat
    41761 cgggtactca atcaacactt gaacgacact taaataataa acttgtccca acggaaaatg
    41821 taggatgccc caaatgaaac ctgccagcat ccctgccttt gtccctcttc ttaacgcaaa
    41881 aagagtcaat ggaatctgcc ctaatgaaat agaaaaactg ctgccgatct ggatcggaat
    41941 caacgacaac accatcgcta acgctgcaac aatcgttcct tctacccaaa ctctattttt
    42001 tcccataaaa aaacttcctc ctttgaataa aaaagtcaca aaggaggaag cagctttcga
    42061 aaatagtcaa acagctgttt attcacaatt cctacgctcg cataaccgat acaggtacga
    42121 agggtttaga aatagattca atctcagccc aattggactc ccctttgtga gtttatttat
    42181 tatttatttt ttgtttcaaa caatggacta actggtttgt tttcatggat acgtttgatt
    42241 gcatctccca ttagtccgcc aacacttact tcatcgattt tgtcgatttt acgatcttct
    42301 ggaagataga tcgagtctgt aacaactaga cgctcgatag ctgaatcttc tattctttgt
    42361 aaagcagggc cggataatac tggatgtgta catgaagcat acacactagt tgcaccagct
    42421 tctttcaaag cattggcagc caatgtgatc gtacctgctg tatcgatcat atcatcgatc
    42481 agtacacaag ttttgccttt gacttgtcca atgatattca ttacttctgc aacatttgct
    42541 tttggacggc gtttgtctat gatcgcaatc ggagatttca aaaattccgc taatttacgt
    42601 gcccgtgtga caccaccatg gtctggtgaa acaacgacaa catcatcgcc tttgattcct
    42661 ttttctaaga aataattggc aataagtggc gcacccatca aatgatcgac tggaatatca
    42721 aagaaacctt ggatttggac tgcatgaagg tccaaagtca gcattcttgt tgcaccagct
    42781 ttttgaatca tgtttgctac taatttcgct gtgattggtt cccgtgcacg tgctttacgg
    42841 tcttgacgcg catagccata ataaggcatg actacgttga ttgtttttgc acttgctcgt
    42901 ttcagtgcgt caatcatgat cagcaactcc atcaagttat cattgactgg gctgctcgtt
    42961 gattgaataa catagacatg cgatccacga atactttctt caatgtttac ttgaatttct
    43021 ccatcactaa attgagtaac agatgatttt cctaactcga cgccgactgc tgctgcaatt
    43081 ttctctgcta atgggcgatt ggaatttaac gcaaaaattt ttaatcttgg gtcaaagtaa
    43141 tgttttgaca tggggacctc cactttcttt ttcacaactc tagaattcta cctaataaat
    43201 agtagtcata ttttttaaat aaatcaagtg attttgcaaa agtcttagtt tagataaggg
    43261 agtttttttg catatccttc tttattgact tgtcttgctc tcgcaattgc cagcgcatat
    43321 tctggaatat tgtctgtaat tgttgacccg gcagcaatcg aactgttttt agctacctcg
    43381 acaggtccga tgatattcgt gctagaacca ataaagctgt ggtcgccgac agtcgtatga
    43441 tgtttgttct ttccatcata gttgacgaag acaacaccac atccgacatt gatttcttct
    43501 cccagcgtag catcaccaac ataagtcaag tgaccgactt tagttccttt gccgatttga
    43561 gcatttttca cttccacaaa gtttccgata tggacgtttt cgccaatttc agcttttggt
    43621 cgtaaatgtg cataaggtcc cacatctgca tgtttcttga catggctgct ttcaatgact
    43681 gagttttcaa tgacgacgtg atcctcaatc ctactgtcta cgatttttga atgtgacccg
    43741 atgacacaat cagaaccaat gactgtattt ccttggattt gtacacctgc ttcgatcaat
    43801 gtgtctggac cgatttctac gcctgcatcg atgtatgtcg ttgctgaatc gacaaagctt
    43861 acgccattga ccatatgcat ctggttaatt cgctttctca tgatctcatt tgctttagct
    43921 aacgcgatcc gatcattgac tcccattgat tcttcaaaat catccgtttg ataagcagca
    43981 actgtatggc cttcttcttt taagatttcg atgatatctg ttagatagta ttcaccttga
    44041 gcattgtttg ttccaacttt gcttaacgca tcgaacaaag cttcgttgtc aaaacagtaa
    44101 gttcctgtat tgatttcttg tacaagagct tcttctggtg ttgcatcttt ttgttccacg
    44161 attttttcta cgatcccaat atggtcacgg atgattcgtc catatcctgt tgggttttct
    44221 gcttgtgccg tcaagatcgt tgcacttgca ttttttcctt ggtgatattc aaaaagattg
    44281 ttcagcgttt cagtagtcaa taatggtgta tcgccactga taactaacgt tgttcctttt
    44341 tttccttcca agaaagaagc agcttgcaaa acagcatgtc ctgttcccaa ttgttctgct
    44401 tgtaacgcat atttactgcg ttctcctagt tgtgctttaa cttgttctgc tccgtgtcca
    44461 acgatcgtaa tcacttcatc tggtttcgtt tcactgaccc gattaatgat atgttctacc
    44521 ataggtttac cagaaacggg atgtaaaact ttatataatt ttgacttcat gcgggtacct
    44581 ttccctgccg ccaaaataat tgcataacgt gcgtccaact gcgtcactcc taaatatagt
    44641 ttgctgattt cagtttatcc cagtataccc attttttcaa caaaacaagt gattttcttt
    44701 tatcccagcg ttttctggat aaaaaaatag atagaccata acgggcctat ctatttggta
    44761 accggtgctc tcctgccaac tcctcggtca caagtcacac tactcataaa acatgaaaag
    44821 ctgttttttg aaatcgtttc ttgtgactta gagttaaacg gtaggcttac aacctcttca
    44881 ttaaacgttt ttcaatcagc tgaccttcgg tattagctca ataaacggca aaatatgagg
    44941 agcaattttt ccgtttattg agctaatact caggacagga cgctgatttc acaacctcta
    45001 gataaacggt gttcaaaagc cagtttctcg gtattaagcc aaatttatga aaaaatgtgg
    45061 aaagccattt tcacaaaatt tttcttacta ctcgaaacta agcggctttt tcacaacctc
    45121 ttattctgaa aaataatttc ctggcacaac cgtaatattt ttcgtttgag tatctacatc
    45181 tttgacataa agcagtgacg tataatcatc gatggcgcga tgaccgttga attttgattc
    45241 ggcaaataca gtgatgccaa caagttctga ttcgaattct tcaatcaagc tcttcattcc
    45301 gttgactgtt ccgccgcctt tcatgaaatc atccactaca aggacacgtg aaccacgttt
    45361 caaacttctc ttagacagtt ccatcttttc aattctttca gaagatccag acacatagtt
    45421 gacacttact gttgatcctt ctgttatttt tgagtcccgg cgtacaataa cgaatggcgc
    45481 attcagataa taggacacag cttgggcaat aggtacgcct tttgtggcta cagtcattac
    45541 agcatcgatt ttttcaccaa ggtatttaga agcaatgatt cttccaactt gacgcagcag
    45601 ttcaggttct cctaacaaat cagagagata aacatatcct cctggaagca gacggtcttg
    45661 ttctgataga cgttctgcta gagattcaat atattttttc gcctcttcat atgaaatttc
    45721 agggatgaac aatacaccac ctgcagcacc cgggattgtt tccaaggttc cataccctcg
    45781 ttctttaaat gttttcttga tgattcccaa atcttcactg atagaagatt tagcagattc
    45841 ataacgttcg gcaaagcttg ttaaggaaat caattcatgc gggtgattca ataaatactg
    45901 tgtcatgtca actagacgtt cactgcgacg tactttcacc tattccaact ccttttaaga
    45961 aattttatcg ttttacatta tataagtttt tcttcaaaaa ttcgagcatt ttatgaaaaa
    46021 ataagaaaat agttcggtat ttattaaaat aaaaagaagc ctataaaaaa tttttcgttt
    46081 ttataaggct tcttttcttt ataatttagt tattttttct tctgaaggca accaatattc
    46141 gtttgatgat atttacaatc aggaacaaag caataaagac taatgtgatt gttgctcctg
    46201 gaggtgtatc tagataaaac gagctagtta gtcctgacag catccctaga aatcctacac
    46261 aaacactgat agcaatcacg acattgaagc ttttgcctaa tcgcataccg attgctgcgg
    46321 gaagaaccat gattgcggat atcaaaagtg caccggcaat cgggatcatc acagcaatag
    46381 ccacaccagt aatcacattg aacatcatcg acatcaaatg aacgggtagc ccatccacgt
    46441 gggcggtatc ttcatcaaaa gtcagaacat acatcggccg tttgaataaa aagaacaata
    46501 taccgatggc aacgaataag attcctaaaa agatgacttg ctcccatgta atggtcacga
    46561 tcgaaccaaa cagataggat tggatacttg ttgctgaatt ccctccgctc aaattcatca
    46621 atactaacgc tagcgccaaa ccaccagcca ttaaaatggc aatggagatt tctgaatagg
    46681 ttcggtagat cgttcgcaga tactccaata tcacagctgc taatacaacg actagcatgg
    46741 tcgtaagtgt aggattaagg ttcaaaaaga atcctaacgc tacccctgct aaagagacat
    46801 gagaaagcgt atcagccatc agcgattgtc ttctgatcac taaaaacaca cctagcatcg
    46861 gggcgattcc ggcaatgaag atagcggcaa gaaacgctct tctcatgaat tcatatgaaa
    46921 gcaacgccat tgagaatcct cctttctcac cagtcggatc tgtctgtccg catactgttt
    46981 gatatcttca tgatcatggg tgatcattag aactgatttc ccatggacat gcgcactatg
    47041 tcggagaaga cgataaaatt catttctgga ttcttcatcc atacctgttg ttggttcatc
    47101 aagaacaaat aagtcagggt cagtagcaaa aatacgcgct aaactgattc gctgcttttg
    47161 tccgccagac aattcaccta ttcgccgatt tcgcatatcc cacatcccta cagcttctaa
    47221 agcacgctgt acatgttgat gatctttttc agagagacgc ttgaaccagc ggcctcttgg
    47281 atatcttcct gaacggacta attcgatcac cgtactagga aaacctgcat tgaaagatgc
    47341 aacttgttga ggaatataac cgatacttaa tttttttcct tcttgatttt tctcagcaat
    47401 ctttatcatt ccttttgaag gtttcagtaa tcctaacgat gctttcacca aggttgactt
    47461 ggctgctcca ttttctccag ttaaaatgac aaattcaccc gcatctacat gataagagac
    47521 atcttctagt acaggttcat catcatagta aaaggtcaaa tcagatattt cgatataacg
    47581 caccttacaa cctccattct aaaacttaat tgatactttc ttttaaagct ttcagatttt
    47641 tttccatgac agaaatataa ttttcgcctg ctttgatttg ttcattagtc aagctttcta
    47701 aaggattcaa cacttctagc ttcactcctg tttcattcga caatgtctca gctaccttcg
    47761 aagaggcatt ttcttcaaaa taaatcactt tgatgttgtt tttcttcaca aattctttta
    47821 gctcagctaa gcgacttggt gtgggttcct gatctggtga aacgcccgaa atcgctactt
    47881 gttttaagtc gtattgattc gctaaataag caaaagcagc atgctgagtg acaaatgtgc
    47941 ggtttgttgc atcttttagc tcatcggagt atttttgatc cagtgcttca agctttttga
    48001 tataagcatc ggcattcttc gtaaaagttt cctttttatc tggatatttt tcgcctaatt
    48061 cttcagcaat cgttctgact tcttttatag ctaataccgg atcgagccaa acatgtggat
    48121 cgtattcatg tgaatgacca tgcccttctt ctgattcttc atgttcgtct gcttcttgcg
    48181 attctaaacg gtcgattcct ttagctgctt cgatcatcaa ggtctgtttg ctatccactg
    48241 aatcctttaa cgaatccaca aaaaattcca tgtctgaact attatacacg aaaacatctg
    48301 catcggaaat ttctgctctt tcttttgcac ttggttcgaa atcatgcggc tccgttccag
    48361 cagggatcaa aagtttcacg tttccttcat cccctacgat ctcttttgta aaatcataca
    48421 tcggataaaa agtcgtaacg atcgtcaaat cctctttttt gtctgcttcc ttgttcgtat
    48481 ttccacatgc tgcaaacagt aaagcaccta tcattaccgt agctgtcaaa agatattttt
    48541 tcatttatat gctcctttca atgaacaaat cgtaatttta cgatttatta acgtgaacta
    48601 atgtatcaaa ataaaaaaac acagtcaata gaaatccatc aatttctgat ttaagcatgt
    48661 atattcttga ttaaatcgta aaatggatga gttgctgctc atatctagcc atttcactac
    48721 aataaaaaac tgaagaatac cattttagga ttcctcagtt tttcatcacc tattttactt
    48781 cttatatttt attgcagggt tcgtactaaa taaacttcct cacaaaaacc ttttaaccca
    48841 ttatatactc tctgcgctct tgaataatgt tgacacaagg caaaaacggt tggtccgctt
    48901 ccactcatca atgcagcatc tgctccgtac ttgatcatac gctctttgat ttgatggatg
    48961 actggatgcc gctttcccgt tatatcttct aaactgtttc ccattttttt gatcatctgc
    49021 tgataatctt gctctcggat ggcttcagca agtccgtgga tgtcttgatg ttggatggct
    49081 tgcgtatcta cttctctaaa cactgtacgt gtagagacac tcattcttgg tttgaccaac
    49141 acaacccagc actgtggcat agaaggtaat acttggattt cttccccttt gccaccgaca
    49201 aatgccgtac ttccgtagac acagtaagga acatctgtac cgacttccaa accgatttct
    49261 gccagttctt ctaacgaaca gcccagattc cataattggt tgatccctct tagagcagct
    49321 gcacagtctg tacttcctcc gcctaatcca gctgctactg gaatattctt cttaacaaag
    49381 atcttgacac cggttttgat attgtattta ttttttagca ataaagcagc ttgataaaca
    49441 ttgttccgtt catctaccgg taaaaatgct ttatttgttt ctacaatgat tttgtcttct
    49501 gttatttctt caaaaaatag atgatctgcc aagtctacgc tcgacatcac catttccaac
    49561 tcatgatacc catcttgccg tctatataat acatccagtc ctaaatttat cttggctggc
    49621 gctttttcaa tcaattccat cctctcaccc attcgaaaag tctaagtcgc aagtattcta
    49681 tcatagggaa aaataaaagt atagcttatg tctgcctagt ggttgatttt gtcatcgttt
    49741 caacagcttt cacagaattt tctcttcata atccaaacaa gttctagtga ttcttataat
    49801 tctgtgagca cttcttctgc caaactcgga acatttcctt tttcttttcc tatcagactg
    49861 agtagctgca tggtagcaaa tccgaaatta cttcctttcc tataagcaaa ataacgtcct
    49921 tcccaatgat cgacatattt taatttcttt tcataagcag actggaagga atagaaaaaa
    49981 ttaccataat tatatacgat atgcatgact ttttcttgaa agaaagaaaa atctgtttct
    50041 ccaacattag ctaatggagc taagcctaga ttggcttccg agtagcccat tttctcgtat
    50101 acaataaaca gattggctaa cagatagtca gctaattcct cagattcttt aggtaagacc
    50161 cgcaacaaat catatcccgc ctgcttcttc gtcatcggct gagcggtgat gaagccaacg
    50221 actttttgat ctttacggac aataccgaca ccgctagata atacatatga tttatcaaat
    50281 cgtcccacag agaagtattt ttctcgtgca ccttgaagcc atttttgtga aacttcattt
    50341 acagcttgat gtaattcttc cggcagttga tcgtaccaag taaaatggta tccttctttc
    50401 atcaaacgtt gatattcaag ttgctgactc agccgagaca agtcttctgt tgctagatca
    50461 acaatccctg cttcacctac tttcgtgaag tgaaaaccca attcatgaag catcactacg
    50521 tagctttctg atatcttata aaacgcaagc tgatagccta aacaatctgc ttgtttcata
    50581 aactgattcg ttgctgcccg catcatttta ggattgccaa ctggatctcc taaaacaaag
    50641 catttgtttc ctttgatctg ataaccaaaa acgacttgat cttggtcgtc ttcttggtaa
    50701 taaaaataac tgtaacctga caagcgaagc tgatggcttg tagctgtgcc tccgtatgtt
    50761 tccaataaac ggtcaaaacg gtctttttcg tactcactgc caagcttcgt agtatcttca
    50821 gctaaatatt gataaagcgc cactaaagct agcaatgaga tgcccaaacc aataagccct
    50881 gagaaccaca catcatctga aggaaacaaa ataaaatgat ttcctgttat tcgaccgact
    50941 aaaaagcgtc cgctgtgata gcctgcaatt gcgtaaacga taaacaaaaa gccgaacaag
    51001 ctagcatcaa agattatagc tccccaagaa taaacgaatt ttgttcgata aaattctttt
    51061 ctggataacc acacagctaa cagaatcaag acatatacca atatcaactg ccaagataac
    51121 gtacgtgtga ttgtatttaa aataccaaaa gatagtaaag caatcgtagg cagaaatgcc
    51181 tttttgactt ttactgaaag tgctctagca aggccgagta ataaaaagcc aaccaataga
    51241 ttcactgtct gatctaaaaa attgaatgag aacggcaata atacttgaaa tagccgactg
    51301 attgcagaca gattagtgat tgttgataga agtaccatca tgatccccgc aaaatagaca
    51361 gcacttacga gcacgatatg cgcaaccttt tggaaaaaca gtcgcggaat gttatctaaa
    51421 aatcgattga ttttgactcc tgtatgtgtg atgaacaata gaagtcccgt cataaaaggt
    51481 agaacataat aaaacaaccg ataatataat agccaaacta ctgctacatc ttgccgaaca
    51541 gacaattgac tcattcctaa gatcatcaaa acgtcaaaag tccccattcc acctgggacc
    51601 atcgtcagca ttcctatcaa tgtagcaatc atgaacatag gatagatcga aagcatcgaa
    51661 atatctattc tcatcaactt gccgatgatc aaaaataccg caagggctcc cgtccattgt
    51721 ccaaaggatg ccagtagcag accaagcaag ccttttggat aaaactcgaa gaacaatgtc
    51781 tttctcttta gataagcaaa aaagaaaatg actggtgcta aaaaactacc gccgaaaagc
    51841 cagatccaat agcttcgaaa aatactttct gactgaataa aaaagacatc aataaatgta
    51901 agaaacgacc atacagacaa accagtcagc ataaatagtg cgacttttga tacagtggct
    51961 aaaaccattt ttctatttgt ctgctttcca taaaaactag cccgcagact tgctcctacc
    52021 acaccaccaa aaccggcgag attgttgatc gtgtttgtta cccacgcagc aagaagaaac
    52081 tcttttcttt ccatttttgg ttttccttgt ttttctaaga ctctgatcgt cacccaatca
    52141 tacaacaaca tcggagtgac acccagcagt ccagccagaa tcatgagcag gatcgtcatg
    52201 cggctttgtt gtcccatcct ttgccaaata tcttgccaac tcatgccatt agcaatattt
    52261 gcgacttgat ttgccacaaa gactaacacg gagccgaaaa aaatcagttt taaaatcaga
    52321 ctatgttcct ttatccattg cagcatcaag tatcgtttat ttttcacatt ttcccattcc
    52381 taacttgtat acttttgtgt cataccccaa tgttatctta tttattttaa tttttccact
    52441 ttagacctgt tctttgcttg cgatgataga aaaagaaaga tatcctaatg ctaaaggaga
    52501 ggataacatg aaagtaggat ttatcggcac agggaatatg gcacaagcta ttattgatgg
    52561 tttattaaaa aaaggaacag tctcgaaaga agaggtgttc gtttccagtg gacattttga
    52621 aaatgcacaa aaatttgctg ctgaaactgg cgtccatgca tgcaaaagta atcaggaagt
    52681 tgcatcacaa tcagatatcg ttcttttagc cgtgaaacca aaaatcattg aaaaagtatt
    52741 ggaagaacta agagaatata gccagaaagt cttattcatt tctattgctt caggaaaatc
    52801 attaatagat ttagaaacag cgcttgaaga tcctcaggcc tccatcgtac gtgtgatgcc
    52861 gaatgtcaat gtcagcgtag gagcaggcgt ttctgcgatt tgcaaaaatg aagctgccac
    52921 ggaggaacag cttcagcaag ctacgatgat ttttgaagca atcggcagcg tctatccttt
    52981 agcagaatca gatttcagta cattcattgg ccttgctggc agctcacccg cattcgttta
    53041 catgctgatc gatgcgatgg gacggactgg tgtactgaat ggtttgtcca aacagacagc
    53101 cactgagatt gctgcaaaag caattatggg ttcttgtcaa aaattccttt caagtgataa
    53161 aaatccatgg gaacttgtag accaagtttc ttctcctggc ggtacaactg ttgcaggtgt
    53221 agttgcctta gaagaagcag gattcatccc agcaatcatc aaaggaatca atacgacgat
    53281 cgagaaagat cttgagatgt tgaataaaaa ataatgatag caatgttttt tcgtgcctta
    53341 caaaaaaaga agagctgtgg cttttgccgc ggctcttctt ttgtattttt tattatttag
    53401 cataatcagt tgcacgagtt tcccgaataa cgattacttt gatgtgtcca ggataatcca
    53461 gttcttcttc gattcgttta cgaatatcac gtactaaacg aacagcgtct aaatccgaga
    53521 tttcttctgg cttgaccatt acccgaactt cgcgtccagc ttgaactgcg taacttgatt
    53581 ctacaccggc gaagctgttc gaaatatttt ccagacttct taaacgacgg atgtagtttt
    53641 ctaatgattc acttcgcgca ccaggtcttg ctgctgagag cgcatctgct gcagctacaa
    53701 ggacagagat aacagaagta gcttccacat ctccatgatg agaagcgatc gcgttgatta
    53761 ctactgggtt ttctttgtac ttggcagcta attccgcacc gatctcaacg tgagatcctt
    53821 caatctcatg gtcaagtgct ttcccaatat catggagcaa cccggcacgt tttgctaatt
    53881 ggatatcttc gccaagctct gctgctaaga taccagctaa ttttgcaacc tcgaccgaat
    53941 gcttcaagac gttttgtcca taactagttc tgaatcgcag acgtccgatg atcttgatta
    54001 gatctggatg aagtgtatga gcaccgactt caaacgctgc ctcttccccg tattcgcgaa
    54061 tacgttcatc catttcttta cgagatttct cgaccatttc ttcgatacgc gctggatgga
    54121 ttcgtccatc ttgtatcagt ttttccaagg tcatccgtgc gatttctctt cggattggat
    54181 cgaatccgga aagaacaact gcttccggtg tatcatcgat gattaaatcg ataccagtca
    54241 gcgtctcaag cgttcgaata ttacgacctt ctcgtccaat gatacgacct ttcatttcat
    54301 cattcggaag ggtaacgact gaaacagtcg tttctgaaac ttgatctgct gcgcagcgtt
    54361 gaatcgctaa tgataataag tttttcgctt tgcgatctgc ttcttctttg gcacgctgtt
    54421 cagattcttt taccattaga gttaactcat gattcagctc ttcttcagtc gatttcatga
    54481 tgacatctcg tgcgtcctct tttgataaac cagcaatttt ttctagttct ttttgttgat
    54541 cttcaatcat tttttcaacg tctttttctc gctcttcaat taattgctgt tttgaactaa
    54601 gtgcttcttc tttactttca agtgagttct cgcgtttttc taacgagtca tctttacgat
    54661 tcagcgtttg ttcgcgttga atcaaacgat tctcttgaga ttttaattct aacttacttt
    54721 ctctcagctc actttcaact tcagaacggt atttctgatt ttcttcctta gcttctaaca
    54781 atgcttcttt ttttagagtt tctgcttctt tttttgcact atcgatgatt ccagcagctg
    54841 atgattgtgc accagctatt tctttctcgt gacgtgactt tgcgaccata aaccctaaac
    54901 caagaccgac aattaaaccg atgatagcga ggagaatgtt gaataccata aaatccacct
    54961 ccatactatc tttttcattt ttatcatcta tacagcttct atgataaatt attctaaact
    55021 cgtcaatatg catcttcgca tatatgtgta caaaaaacat gcacaacttt attctaatgt
    55081 ttgtaccccg tagtgtcaac tttaaataaa caa
//
LOCUS       DAZKCW010000013        52541 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000013 DAZKCW010000000
VERSION     DAZKCW010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.013"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..733
                     /locus_tag="ACG84Z_000851"
     CDS             <1..733
                     /locus_tag="ACG84Z_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFP9161713.1"
                     /translation="LSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLN
                     VALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYS
                     YGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYIN
                     KGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKL
                     LGSIQTNLPESVLLDCGMDFLKDIC"
     gene            791..2830
                     /locus_tag="ACG84Z_000852"
     CDS             791..2830
                     /locus_tag="ACG84Z_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFP9161714.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLLAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2939..4090)
                     /locus_tag="ACG84Z_000853"
     CDS             complement(2939..4090)
                     /locus_tag="ACG84Z_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFP9161715.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4244..4774)
                     /locus_tag="ACG84Z_000854"
     CDS             complement(4244..4774)
                     /locus_tag="ACG84Z_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFP9161716.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4873..5223)
                     /locus_tag="ACG84Z_000855"
     CDS             complement(4873..5223)
                     /locus_tag="ACG84Z_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFP9161717.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5380..6909)
                     /gene="ahpF"
                     /locus_tag="ACG84Z_000856"
     CDS             complement(5380..6909)
                     /gene="ahpF"
                     /locus_tag="ACG84Z_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFP9161718.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6919..7482)
                     /gene="ahpC"
                     /locus_tag="ACG84Z_000857"
     CDS             complement(6919..7482)
                     /gene="ahpC"
                     /locus_tag="ACG84Z_000857"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFP9161719.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7626..8288)
                     /locus_tag="ACG84Z_000858"
     CDS             complement(7626..8288)
                     /locus_tag="ACG84Z_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9161720.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8472..10118
                     /locus_tag="ACG84Z_000859"
     CDS             8472..10118
                     /locus_tag="ACG84Z_000859"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFP9161721.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10109..11191
                     /gene="uxuA"
                     /locus_tag="ACG84Z_000860"
     CDS             10109..11191
                     /gene="uxuA"
                     /locus_tag="ACG84Z_000860"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFP9161722.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11299..12852)
                     /locus_tag="ACG84Z_000861"
     CDS             complement(11299..12852)
                     /locus_tag="ACG84Z_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9161723.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            13000..14168
                     /locus_tag="ACG84Z_000862"
                     /pseudo
     CDS             13000..14168
                     /locus_tag="ACG84Z_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(14294..15373)
                     /locus_tag="ACG84Z_000863"
     CDS             complement(14294..15373)
                     /locus_tag="ACG84Z_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFP9161724.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(15476..15916)
                     /locus_tag="ACG84Z_000864"
     CDS             complement(15476..15916)
                     /locus_tag="ACG84Z_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9161725.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(15973..16383)
                     /locus_tag="ACG84Z_000865"
     CDS             complement(15973..16383)
                     /locus_tag="ACG84Z_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFP9161726.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(16563..16997)
                     /locus_tag="ACG84Z_000866"
     CDS             complement(16563..16997)
                     /locus_tag="ACG84Z_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9161727.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(17097..17945)
                     /locus_tag="ACG84Z_000867"
     CDS             complement(17097..17945)
                     /locus_tag="ACG84Z_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9161728.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            18334..20100
                     /locus_tag="ACG84Z_000868"
     CDS             18334..20100
                     /locus_tag="ACG84Z_000868"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFP9161729.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            20202..21461
                     /locus_tag="ACG84Z_000869"
     CDS             20202..21461
                     /locus_tag="ACG84Z_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFP9161730.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            21608..22909
                     /locus_tag="ACG84Z_000870"
     CDS             21608..22909
                     /locus_tag="ACG84Z_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9161731.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            22912..23763
                     /locus_tag="ACG84Z_000871"
     CDS             22912..23763
                     /locus_tag="ACG84Z_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFP9161732.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            23776..24591
                     /locus_tag="ACG84Z_000872"
     CDS             23776..24591
                     /locus_tag="ACG84Z_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFP9161733.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            24742..25908
                     /locus_tag="ACG84Z_000873"
     CDS             24742..25908
                     /locus_tag="ACG84Z_000873"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9161734.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            26138..26785
                     /locus_tag="ACG84Z_000874"
     CDS             26138..26785
                     /locus_tag="ACG84Z_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFP9161735.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            26869..27813
                     /locus_tag="ACG84Z_000875"
     CDS             26869..27813
                     /locus_tag="ACG84Z_000875"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFP9161736.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            27948..29399
                     /locus_tag="ACG84Z_000876"
     CDS             27948..29399
                     /locus_tag="ACG84Z_000876"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFP9161737.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            29420..30256
                     /locus_tag="ACG84Z_000877"
     CDS             29420..30256
                     /locus_tag="ACG84Z_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFP9161738.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            30256..30915
                     /locus_tag="ACG84Z_000878"
     CDS             30256..30915
                     /locus_tag="ACG84Z_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFP9161739.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            31041..31730
                     /locus_tag="ACG84Z_000879"
     CDS             31041..31730
                     /locus_tag="ACG84Z_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161740.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            31736..32692
                     /locus_tag="ACG84Z_000880"
     CDS             31736..32692
                     /locus_tag="ACG84Z_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFP9161741.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            32736..33248
                     /locus_tag="ACG84Z_000881"
     CDS             32736..33248
                     /locus_tag="ACG84Z_000881"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9161742.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(33504..34052)
                     /locus_tag="ACG84Z_000882"
     CDS             complement(33504..34052)
                     /locus_tag="ACG84Z_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFP9161743.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(34141..35322)
                     /locus_tag="ACG84Z_000883"
     CDS             complement(34141..35322)
                     /locus_tag="ACG84Z_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFP9161744.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(35558..37066)
                     /locus_tag="ACG84Z_000884"
     CDS             complement(35558..37066)
                     /locus_tag="ACG84Z_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFP9161745.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            37225..37416
                     /locus_tag="ACG84Z_000885"
     CDS             37225..37416
                     /locus_tag="ACG84Z_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161746.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            37619..38536
                     /locus_tag="ACG84Z_000886"
     CDS             37619..38536
                     /locus_tag="ACG84Z_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFP9161747.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            38529..39602
                     /locus_tag="ACG84Z_000887"
     CDS             38529..39602
                     /locus_tag="ACG84Z_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161748.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            39750..40268
                     /locus_tag="ACG84Z_000888"
     CDS             39750..40268
                     /locus_tag="ACG84Z_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161749.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            40249..40641
                     /locus_tag="ACG84Z_000889"
     CDS             40249..40641
                     /locus_tag="ACG84Z_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFP9161750.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            40717..41652
                     /locus_tag="ACG84Z_000890"
     CDS             40717..41652
                     /locus_tag="ACG84Z_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFP9161751.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            41785..42564
                     /locus_tag="ACG84Z_000891"
     CDS             41785..42564
                     /locus_tag="ACG84Z_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFP9161752.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            42557..42874
                     /locus_tag="ACG84Z_000892"
     CDS             42557..42874
                     /locus_tag="ACG84Z_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFP9161753.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            43118..44728
                     /locus_tag="ACG84Z_000893"
     CDS             43118..44728
                     /locus_tag="ACG84Z_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFP9161754.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            44885..45733
                     /locus_tag="ACG84Z_000894"
     CDS             44885..45733
                     /locus_tag="ACG84Z_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFP9161755.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            45964..46443
                     /locus_tag="ACG84Z_000895"
     CDS             45964..46443
                     /locus_tag="ACG84Z_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFP9161756.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            46476..48704
                     /locus_tag="ACG84Z_000896"
     CDS             46476..48704
                     /locus_tag="ACG84Z_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9161757.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            48833..50476
                     /locus_tag="ACG84Z_000897"
     CDS             48833..50476
                     /locus_tag="ACG84Z_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFP9161758.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(50549..51094)
                     /locus_tag="ACG84Z_000898"
     CDS             complement(50549..51094)
                     /locus_tag="ACG84Z_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFP9161759.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(51117..51602)
                     /locus_tag="ACG84Z_000899"
     CDS             complement(51117..51602)
                     /locus_tag="ACG84Z_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFP9161760.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(51592..52404)
                     /locus_tag="ACG84Z_000900"
     CDS             complement(51592..52404)
                     /locus_tag="ACG84Z_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFP9161761.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
BASE COUNT        17519 a         9526 c        10149 g        15347 t
ORIGIN      
        1 attatctatt ttgttactgc ttacattagt agttggctat ttttcgattg agtttatcca
       61 tggattttcg tctgcaaaac agagttcaac tgtgaaaaag gtagagccga aaagtatccc
      121 taccacacta aatgtggctt tgattggttc agatgctcgt tcgaaagacg aaaacggtcg
      181 ctcggattca cttctggttg cacaatacaa ccagaaaaca caacaagcaa aactgatctc
      241 tatcatgaga gattcatatg tcgatattcc aggttacgga atgaataaga taaatgcagc
      301 ttactcttat gggggagttg atttattaaa tcaaacatta aaggaaaatt tcaaatttga
      361 agctccctat tatgcaagta tcacatttca agattttatc gattgcgtta atgaactgtt
      421 tcctggtgga gtcaagatcg atgcagaaaa atctctagat ttagatggcg tatatataaa
      481 caaaggagag caagtgatgg atggtaatac tttactccag tatgctcgat ttcgggaaga
      541 caaagaagga gacttcggga ggatcagaag gcagcagcaa gtgatcaaag ctatctctca
      601 gcagctgaaa gacgtaactt caatattcaa gctacccaaa gcggttggga aattacttgg
      661 tagtatccaa acgaaccttc cagaaagtgt gcttctggat tgtggtatgg atttcctcaa
      721 agacatatgt tagaataaac aggtataaat agtgaaataa aggaatgaca agcaagagaa
      781 ggaggaaaaa atgaaaagaa gtgacaagca cggcaaaaat cgaacaggcg cttatattgc
      841 cggcgcagtg atcttaatag cagctgcggg tggcggttat ttttactacc agcactatca
      901 agaaacccaa gcagtagaag ctggagaaaa gacagttgag caatttgtcc aagctttgaa
      961 caagggagat tataacaaag ctgcagaaat gacatcaaaa aaggcggcaa ataaaagtgc
     1021 attatctgaa aaagagatct tagataaata ccagaatata tacggtgctg ctgatgtcaa
     1081 aggacttcag atatcgaatc taaaagtaga taaaaaagac gattctactt acagtttttc
     1141 atataaagca aagatgaata cctcattagg tgaattgaaa gatctttctt ataaaggaac
     1201 attagacaga aatgatggtc aaaccacgat caactggcaa cccaacttgg tttttccaga
     1261 aatggaagga aatgacaaag taagcctgac cacacaagaa gcagcaagag ggaatattat
     1321 agatcgaaat ggtgaaccat tagcaacaac aggcaaacta aaacaattag gagtcgttcc
     1381 aagtaaactt ggagatggag gcgaaaaaac agccaatatc aaagcgattg cttcctcctt
     1441 cgacttaaca gaagatgcta tcaatcaggc gatttcacaa agctgggtac aacccgatta
     1501 ctttgtccca ttgaaaatca ttgatggagc aacgccagaa cttccagctg gagctaccat
     1561 tcaagaagta gacggcagat attatccttt gggtgaagca gctgctcagc tgattggtta
     1621 cgtgggagat atcacagcag aagatattga taagaatcca gaattaagca gtaatggaaa
     1681 aatcggtcgc tcaggtttgg agatggcttt tgataaggat cttcgtggga caacaggtgg
     1741 gaaattaagc attacagatg cagacggtgt agagaaaaaa gttctgatcg aacatgaagt
     1801 tcaaaatggc aaagatatca aattgacaat cgatgcgaag gcacaaaaaa cagcttttga
     1861 cagtctagga ggaaaagctg gatcaactgt tgcgacaacg ccaaaaaccg gtgatcttct
     1921 tgcgcttgct agctctccaa gctatgatcc aaacaaaatg acaaacggga tctcacaaga
     1981 agattacaaa gcttatgaag aaaatcctga acatccattc atcagccgat ttgcgacagg
     2041 ttatgctcct ggatctacgt ttaaaataat tacagcagca atcggtctcg acaacggcac
     2101 tatcgatcca aatgaagtgt tgacgatcaa cgggcttaaa tggcaaaaag acagttcttg
     2161 gggatctttt caaacaacgc gtgtcagtag tgatgtatca caagtagact taaaaactgc
     2221 tttgatctat tccgataata tatatgcggc acaagaaacg ttgaaaatgg gtgagaaaaa
     2281 atttcgtaca ggcttagata aattcatttt tggtgaagac cttgatttgc caattagtat
     2341 gaatccagca caaatttcta atgaagatag ctttaactca gatatcttgc tagctgatac
     2401 tggatatgga cagggcgaac ttctaattaa tcctatccag caagcagcaa tgtattctgt
     2461 ttttaccaac aatggcacac ttgtctatcc taaattgatt gcagataaag agacaaaaga
     2521 taagaagaat gtcatcagcg aaacagcagt acaaacgatc gtgccagatc tgagagaagt
     2581 tgtgcaagat gtaaatggta cagcacattc tctttctgct ttagggattc cgttggcagc
     2641 gaaaactggt acagcggaaa tcaaagaaaa acaggatgta aaggggcaag agaacagttt
     2701 cttgcttgct ttcaatcttg ataaccaagg ttatatgatg gtcagcatgt tggaaaataa
     2761 agaagatgat gattcagcaa ccaaacgagc atcggaacta ttgcaatacc tcaaccaaaa
     2821 ttatcaataa aaaattgctt tttaagtaca gtaaaaggac tgtggcgtta tcgtcacagt
     2881 ccttttttca aataaacggt tttcacgatg tctctttcac aacttctttt tgatttactc
     2941 acacttcata aacttttttt gtaaaatatt tgagaacaag tggagaaata agtgtactta
     3001 ataaaatcac gataactaaa ggtgaatagt actgtggttc gatcaattga ctttgctgtc
     3061 caatttgtaa aatgatcaaa gccatttctc cacgcgaaat cataccagca ccgaccatca
     3121 atgaactatg ttgagaaaaa ccggcaatct gagcaccaaa ataacctcca agcaatttgg
     3181 tcaaaatcgc tacaagcgtc aatatagaaa taaagagtag ttgttcacta aagtcagaaa
     3241 aatcaacttc taatcctaca ctgacaaaaa atactggtat aaatactgca tatcctaaag
     3301 cctctacatt gtggtatact tcttctttaa cctttgtctg actgacagct atcccagcaa
     3361 aaaaagcacc aatgacagag ctaagcccaa caagatccgc tacgtaagac attcctaaac
     3421 aaataactag cgatacgatg ataatagaag aatttgcgta cactttttct gcaaatgaaa
     3481 gtaggaaagg cgcaatccat ttgactaata agaaaataaa aacaaaataa attagctgtt
     3541 caatcaaaac aagcggtaaa gaagcattgc tagaagcttc ccccgttaga aaagataggc
     3601 tgaaacttag aactaaaacg actaaaatgt catctaccac agaagcaccc aaaattgttg
     3661 atccttcttt tgtattcact acgtttagtt cttttaatac ttctactgaa atactgacag
     3721 aagttgccgc aagaataatc ccaaagaaaa tcgcttcatt tcccgaaact tggaatgctt
     3781 tgcctgtcaa ccagccaaaa acaaccggga agatgatccc aagcaaagca acgaacatac
     3841 caggtcggaa atattttttc aaaagagata aatcactttc cagaccagct aaaaacatta
     3901 ataagatcac accaatctcc gaaaagtcat ggactagaat atcaggtttg acccaattca
     3961 atccagcttg gcctagcaaa acaccaacaa gtaattgtcc aatcactgct gggataccta
     4021 atctccgcga gatatgtgag ccaatcgttg ttgaaatcaa tatcaggcat aaaataccaa
     4081 taaattccat tctcatcatt cctttgtata aaatatagcc cgaacttagc ataacataca
     4141 ttattgaaaa aataggaaaa tatactcaca aaaaaaccaa caatccaaaa gatttttttg
     4201 gattgttggt ttttatacgg tctattttaa taactaaaaa tgattaacgt atagtcattt
     4261 ttcttattct gatgaaattg ataatctcct ggatgcccat gaaaatcaaa ataaagccga
     4321 atatttggaa tagaagcatc aaacttttga atggattgaa caataagacg aatccgccaa
     4381 tcaacaacag aatactacta taaacactcc aacttttagc ttttgtattc atgctgaaga
     4441 acaactggaa caagctgttg atgataacag ctaatccaag aagaatcggc aggatagaaa
     4501 cgattgcagg tgcaaaagca tagacgatca gagctaagat caggaaaaaa agaccactga
     4561 acagaccgat actccaagaa cctgttttcc ttttaaaacg gtaagcctca aaaagattca
     4621 acaacccaag caaaacaaga taggcggtga tcagataacc gataaaatga aaaacagcag
     4681 aagggtttag cacaatcgca atcccagaaa taatataaac agcagctctt aataaggcgt
     4741 atttttgaat attttgttta atcgtctcaa acatataaga aaacctcctt tgacttattt
     4801 taacgtgaac tagtcatttt accaaattaa atgttacaaa atgagcgaag gagaagaata
     4861 tctctggaaa aatcaacttc tgaggatctt ttccattttt ttgccttttg ctagctcatc
     4921 gatcatttta tctaaataac gaatttcttt catcaagtta tcctcgatgt cttctactcg
     4981 tacaccacaa acaacacctg taatcaagga acgtgaagga ttggggacag gggcttccgc
     5041 aaaaaattgt tcgaaagtca cttgtttttg tagttgatat tctagttctg tttgggaata
     5101 acccgtcagc caacaaatga tttcatctac ttcctctttt atacgatctt ttctctccgc
     5161 ttttgctaca tacataggat aaacgcttgc aaaacttgtc gtaaaaatac gattttgcgc
     5221 cataatcagt cacctttctt tttttcaaat tatttactac ttatagtata taagaaaaag
     5281 agaagaaaaa gcgattattc aaaaaaacaa aaaggattgt gacaaaattc ttgtcaccat
     5341 ccttttttcc gctctctgac tttttacaat cttcatagct caagtgcgca tcagataatc
     5401 gaatgctcct aaagctgcag tagctcctga acccattgaa acaatgattt gtttgtatgg
     5461 actatctgta caatcaccag ctgcgaaaac gccggggata ttcgttgcgc catttttctc
     5521 ggtcactatt tcatttcttg gattcatttc gatcgttcca tctagccaat ccgtattagg
     5581 gagtaagccg actagaatga atactcctga aacagctagt gtatgcatct ccatcgtacg
     5641 gcgatcgata taggagagag attctacctg attcgtaccg ctgatttctt tcgtcgctgc
     5701 atgtttgata acagtgacat tcgcaagaga gactagttta tcctgtaaga tttgatctgc
     5761 ttttaattct ggtaagaatt ctagaacata tacatgtttt gctaacccag ccaaatcgat
     5821 tgctgcttca acaccagaat taccaccacc gataacagca atctcttttc ctttaaataa
     5881 agggccgtca cagtgtgggc aataagcaat tcctttattt ttaaactctt tttcgcctgg
     5941 tacattgata gaacgccagt gcgcacctgt cgcgatgatg gcggtttttg ctttaagtga
     6001 tataccgtta gctaagccaa tattaataaa atgttgctct ttatttaagg aaacggcctg
     6061 ttgattcatc ataatgtcga tagggtaact acgcacatga ctttctactt gctgcatcaa
     6121 ttttggacct tctgtgtaag aggtaccaat catattttca atccctagtg tttcaacgac
     6181 ttgtccgccg aaagaatcag cgacaagtcc tgtacggatt cctttacgtg ctgcatagat
     6241 agctgcacta ctagctgctg gtccaccgcc aattactaat acatcataag gttctttttc
     6301 aaacaactct tcttcaatca aagggccagt gattttttca acaatttgtt cgatcgtcat
     6361 gcgtccgcta ctaaattctt ctccatttaa aaacacagtt ggcactgcca tgattttttt
     6421 atcatcgatt tctttttgga acatcccacc ttcaatcatc gtatgagtaa tatttggatt
     6481 taatacagct aatatattca atgcctgtac aacgtcgggg caattatgac aagtcaagct
     6541 aacataactg tcaaaatgca atgtttgtgt tatttttttg attttaagac tcaaagattc
     6601 actgattttc ggtgcccgtc cactaatttg taacatagcc agtaaaaaag aggaaaattc
     6661 atgaccgagg gggataccag caaaaacgat tccactttct ttgccaactg gattgataga
     6721 aaaactaggt gtgcgcatcg aatctctttt ttcccaagag attttaggag acatttctgc
     6781 tatttccttc gtaaattcag ctagtttttg actattttca ctattatcca aactaacaga
     6841 aaaaacaata ggagattcaa tcagtgctaa atattgttcg agattttgtt tagtttcttt
     6901 gtctaacata tccaccacct aaatctttcc aacaagatca aaacttggtt tcaatgtttc
     6961 gccactttct ttccattttg ccggacaaac ttcacctggg tgggtacgta catattgagc
     7021 agcgcgaatc ttatcaatca gtgcactagc gtcacgaccg attccatctg cattgatttc
     7081 catagcttga acgattccgt ctggatcaat aataaatgtt cctcgctgag ctaatccttg
     7141 ctcttcatcc aaaacatcaa aaatacgaga aatctgatga gacggatcac cgatcatcac
     7201 gtattcgatt ttaccgatag catctgatgt atcatgccat gctttgtgag taaagtgggt
     7261 atcggtagag caagaaaaga cttcaacacc taaagatttc aatgtactgt attgttcttg
     7321 taagtcttct aattcagtag gacaaacaaa agtaaaatca gctggataga agcaaagaat
     7381 actccagttc cccataagat ctttttcact gacttctaaa aattctcctt gatgataagc
     7441 atgtgcatta aattcttcga tttttttccc aatcaatgac atagtaaaac ctccaataat
     7501 aattatttat ttataattat tgtaatttag ttggagttgc aaagtcaatg gatattttgt
     7561 tatttaataa agattactca aaaacgaagg ttaattataa aaatagaaga ggtcgcaaga
     7621 aaatgctact gctggaaata ctcgggataa cgttgagtaa cagtttcctg ttctttcagc
     7681 atcatgtgta agtgcaatcc cgtttgaaat cgagcttctt ctggtttttt atcaactaaa
     7741 gccttgagta aatcataatg ttgttccatg atcgtttccc atggaagccc ctgaatggtc
     7801 actcgtaacc agcggaaacg ttctaaatgg gtattatggt catctaacca gttccaaact
     7861 tcttttcttc ctgcaatttc gaaacaagct tcatgaaata aattatctgc acggaaaaaa
     7921 gcgcgttcgt catttatttt gactgctttt tcttgttctt ctaaaatcgt ttctagcact
     7981 attcgtgttt gtgtgtccaa tttggaacaa cattcaatca tgatttgctc ttccaactgt
     8041 tctcggacaa agcgagcatt ttctgcagaa acaagattaa ttttggaaac atacgtacca
     8101 ctttgaggta tcgtatacac gagttcttgc tgacgtagtt gaatcaatgc ttcgcgaatg
     8161 ggagtccggc cgatagcaag atgttcctcc agtgcctttt cagatatttt ccttccaggt
     8221 tctaagtcag catagataat ttgtttacga atcgcttgat aagcttgtga ttgcaagctg
     8281 cttttcatct ttattcctcc aaaatcattt ctatgaacgt agtataacag aagaggtctg
     8341 aaaaacaatc tggtatgtca cattaactag taaatttgta taaatagtaa aattttggtt
     8401 gacatagcga tttttattgt ataaaattca cttgaataca aaaactaata tgttagttta
     8461 ggaggggaaa aatgattgat ttaaacaact ggaggaactt tatccctgaa ttatctcaaa
     8521 aagaagtaga aatacctcat tttgaccgtg catcattaag agaaaatgga caaaaaaatc
     8581 ctgtctggat ccatttcggt ggcggaaatc tttatcgagg atttcatgca gaaatcgctc
     8641 aacgtttagc ggatctaggc gaattgtcca ctggtgtcat tgtttgtgaa acattcgatg
     8701 aagaaataat tgaaagggct taccaagatt ttgatgattt gattcttgaa gtggtcatgc
     8761 caagcagtgg agagttcgtc aaacgtatat tagctgcgac agctgacagt ctgtattgtc
     8821 atccagattg ttctgaacac tttgataaga tgattcgaca ctttgaaaat cctagtttac
     8881 aattagttac ttttgctatt actgaaaaag gttatcgatt gaaagataca aataataaat
     8941 atataggacc gattgcagtc gatataaaaa atggtccaaa gaagccatca catacaatga
     9001 gtattcttgc tgcgctactt tataaacgtt ttttatctgg agcttggccg attgcacttg
     9061 tctctacaga taatttttca caaaacggta gtcaattacg tacttctttg ctaacgatcg
     9121 caaaagaatg gcaaaaggaa ggttatgtac aaaatacatt tatccaatac ttatcgaatg
     9181 aagaaattgt tgcgtttcca tggacgatga ttgatcgtat caccccgaat ccttccttgt
     9241 cagttagcaa aatgttggca aaagagggct tttcaaatat gtcgattttc caaaccgcaa
     9301 aaggaaataa tattgctcca tttgtcaata cagaggacat ccattattta atcatggaag
     9361 atcattttcc caatggacgt ccgaaattcg aaaaagctgg ggtattcttg actgatcgtg
     9421 caacggtaga taaagcagat acgatgaagg tgacgacttg ccttaatcct ttgcatacgt
     9481 ctttagctat tatgggttgt ttactggggt ataggagcat agctgaggag atgaaagatc
     9541 cagatttatc gctgctagtt tctgaaatcg ggtacaatga aggcctccca gttgtggagt
     9601 ctccaggtat cattgatcca aagatctttc tggaagaagt aattactgtg cgcttttcta
     9661 atccaaatat tcctgatatg cctcagcgaa tcgccacgga tacctctcaa aaggtggcga
     9721 ttcgttatgg tgagacgatt aaaaaatata tggaaataga agttaaagac ccgcagacac
     9781 ttgtattcat accattgact ctcgctgctt ggcttcgata ccttattggc attgatgatc
     9841 aaggaaaacc attcatcccg agtccagacc cactattgac agactttcag cataagcttt
     9901 ccgatattca actgggtacg caagatacat cacatattca tgagaaaatg gctcctattt
     9961 tgtcaaataa agaaattttt ggtgtagatc tttaccaagc agagcttggc agaaaaatag
    10021 aagaaatgtt catcaagatg gtagcaggac cgaatgccgt acgaaaaaca ttacaggatt
    10081 acttacaaga acatggagga aatttatcat ggaaatgact tttagatggt acggatcaca
    10141 ggaagaaaag attaccttag atgaaatcag acagattcct gcggtcaaag ggattgtagg
    10201 cacattgatg gatataccag taggagaggt atggcccagg gagaggatca aagaactaaa
    10261 agaagaaatt gagtctcgtg ggttaacact aaaagtaatt gaaagcgtca atgtgcatga
    10321 tgccattaaa attggattac cttcccgtga gcagtatatc gaaaactata agcagacaat
    10381 ccgaaacttg gcagaatatg gaatagaagt catctgctat aattttatgc ctgtatttga
    10441 ctgggtgaaa tctgaccttg actaccgctt agaagacggc tcatccacgt tagcttttat
    10501 atctgatgat attccagatg atccaagaga aatcgtcgcg cgcatcgaac attccagcaa
    10561 tgaatttgaa ttgccgggat gggaacctga gcgcttagct catatcaaat ccttgcttga
    10621 agcctatgca tcagtagacg aagaaaaact tcgagaaaat tttgcctatt ttctccaatc
    10681 aatcatccca acatgtgaag aggtaggggt caaaatggct gtacatccag atgatccgcc
    10741 atactcgatt tttggattac ctcgaatcgt aaagaatcga gaagatttag attggttgtg
    10801 ccgcatagta gacagccctt ataacggaat cactctttgt acagggagta ttgcagaaga
    10861 tccagaaaat gatgtatatg ggattttagc agaattttgt caaagagatc gaatcccatt
    10921 tgcacatgtt cgaaatatta aatttttagc taatcgagat ttctatgagg caccgcataa
    10981 atccgaatac ggttcattag acatgtaccg catactaaaa acaatgtatg acaacggatt
    11041 taacgaatac atccgtcctg atcatggaag aatgatctgg aatgagacag gaagaccagg
    11101 atacggctta tatgatcgag cattaggtgc tgtttatcta aatggattat gggaagcaat
    11161 cgaaaaagga aacaaaagta aagataatta gtgaaaaaaa ctgtaatttt attatgtaaa
    11221 taagaaggat gttcaaattc ttgatacata aatccggagg ttgttaataa gcattcggat
    11281 ttatgtatct tatttggtct aggaagtaac ttgattttct tttttcgatt gatccatgag
    11341 tgcttcttct tttaattcaa agatatattc tgagatcctc ataatcactt ttttccagtc
    11401 ttctggtgtg atgattcctt ttaaaatata gatttttttg atatgagaag gcaattgttt
    11461 caaagggcag tcgctgataa cgatgttgca gttctccata aaatcatttt gtattttgat
    11521 cgattcattt gaaaaaattt gttctatctt aacgatcaga tctttactga tataaaaatc
    11581 acgcgtatag ttcacaccaa tcacaattcg cggctgtttt ttgtagcgat catacaaatg
    11641 tactaggtct tcaaccatcc attgcacatt ttccttttct aaaataactg gtaacaagtg
    11701 ttgattttgt tctctgaaat ccatataaaa ttgttcaatg gcggtttgga cttctttcaa
    11761 cacgctatgt tcttgataaa gcatgaaagt aggaaggggc gtatttggtt gattgaagtt
    11821 aagaaatcca ttataaagtt tatttcgtgc gaatgccaat gagtaaagaa tcttttcttt
    11881 ttcaggtata aacaaatcaa atacagtaca aaaggactcc accatttctc ttgaataaag
    11941 aacatgagga acgtttgctt tttttaaaag tttgtattgc tccaagcttg tttcttccga
    12001 ttcgattttc gtgatagaaa gtcgagctaa aatattcact aagatgcgtt gttcgcgaca
    12061 aattggcaga ttaggtcgca aaatatctac agagggatca ataaaaaagt caatatattc
    12121 atactctgtg aattcttttt gtacgtcttt cacagaagtt gcaggaaaat tctctttaca
    12181 tatttttaat agaaaatata atttatctat cataccgcta tttagtcggt caagtacttc
    12241 ttttttaaaa aaagtattca tcataaaagc cactacttgc ggatcttcat cataaaattc
    12301 tgtagcagta cttgaaaaga tgttccaata aatatctaat gctgcatatt gaatttgtac
    12361 ctcttttcca gaaaaagact ttctgccatt attagaaaag gagatagaca aaccgtacaa
    12421 tgctaaaaat gcattaatct ttttcatttt cgtatacaaa taagaggcac tatagtttgt
    12481 ttgctgactt aaactgataa tcgaatttgt ctgacagctg aacaaagaag tcaagatctg
    12541 ataactgact gattcgttgc agtatcttcc aaatagacga taatagcagt aagccggatc
    12601 aattccttca aaattcaact ttaaaaaagg tttttgctta tcaatatgca gttctgttag
    12661 attgagacgc tcaaagtctt gttctaattc tttgatgtat agtaaaaaat ttgattcaga
    12721 catatggaaa tgatctgcta aatattgtgt agtaataaag aaacgatgtt cagataggaa
    12781 aagaaaaata tctaattttg tattgctttt tttcttcaag agaaacgttt taatcgcttc
    12841 ttgagtttgc atgaaagagg ctccttttta cttaaattgt taaaacttga aaatattact
    12901 gtttttttca taaatttaga caaaaaaaca gtaaacatat aggtagaatc tctactatct
    12961 tatttcttgc atacaaaaaa atcaaggagt gagagagtta tgagatattc aaccatctta
    13021 atatcaacat ttgcagcctt aagcttatcg cttactataa atcagacagt ccacacagag
    13081 gagatagaaa cagccaaatg gacagaaacc aagtgggcca acgtcaatcg aattaccttt
    13141 caggatgaat tttcatcctt caattcagga gtcgcaaaat taagaaaagg acaaacagcg
    13201 accatcaaag caaaaattga ctattcagga gacttagcac ctatactaca atcagctgtt
    13261 acatttgaga atgttgatcc cgctttgtcg attggctatg acgagaacac tttgactatc
    13321 caacacaagc aagcgatatt taccttcacc gttacattaa atcaggactt gttaaaacca
    13381 gcgcttttta ctgtcaaggt atcagatgga ctaccgaacg atcatcatca tttaacgccg
    13441 tatagtcagc ggcagacaat tgagcaagat tcagctatcg actcaggagg agatcttgtt
    13501 gaagaaccaa cagataaacc agaaaatgaa aataagccag aagtaccgcc tacagaaaat
    13561 ccagacggag aacagaaacc ggaaatagaa cctggagaag aacccgatac agaaactcaa
    13621 ccagagccag acaatgaatc aaaacctgaa ataacccctg gagaaaaacc agatgtagac
    13681 ccagaagaaa aaccagatgt gactccagaa ccagatacgg attctggaaa ccaaacagta
    13741 ccggaaacaa atccagacac agataatgaa actgaaaatc cagaaaaacc agaggtagat
    13801 ccagaagaaa aaccagatgt gactccagaa ccagatacgg acgcaagaga ccaaggaata
    13861 ccagaaaaaa taaacaaaaa aacaattcaa gaggatggaa aaaaagagag taaaaaatca
    13921 aatctagcaa ttctaaaaat aaatgaagag cagctgaata aaaaatcacg aatatttgat
    13981 agcgcccaat cagctgaaac cttaaaaagt agcaaggata caacctttgc tgtcctgaaa
    14041 cgaaaaataa acagctacca aaatccggag agtcacaaaa caaagttata ctgtggagcg
    14101 gaatcattct attaagtata gcaacaatgc tttctgcaaa aagatttaaa caaaacagat
    14161 ctctctaaca tttgaataat gtctgtgaac gcatttttca aataaaaaga aatatccaga
    14221 aaatgacccc aaaataccag attgaaatct gatatttggg gtcgttcata ctttatcttt
    14281 cttcatattt attttaaggg atatctgttt cttttggaag atggttcggg atctttttca
    14341 ctttcaatac atctaaaaag aaggtaaaga tcggaatgcc gacaatcaag ccccaaacgc
    14401 caaagaaccg ttcgctaaca agtaagacca caaatgtata aaaaatcggc agttctgttt
    14461 tgctggacat caacttcgga ttcagcacat aagactcaat tagatggaca atcaaaatcg
    14521 taatcaggat ataaacaaca tctcggatgc ctccttggga ataagctatg aaagatagag
    14581 gaatacaaga aatgataaca cctgctactg ggatcagact taaaatgaaa atcatgatcg
    14641 ctaaactcag cagctgatga aagccaaata cagccaaggc gattgtagtg agcaacgtat
    14701 ttaaaagagc gacaacaaat tgagcttcta ataccaaacc aaatgtattg acaaacttat
    14761 cggcaaaata gtaaatatct tgaaagaacc aagaaaattc actttttaaa aacaatcttg
    14821 agaatacaat tgtttttttc ttttcaatca taaaaaagaa acttaagatg aatgacatag
    14881 caaacgccac tgccattttt cctatatcct gtaaatagcc aagcgcaatc gaagcgccat
    14941 tttgaagctg ttcaaaaaaa tcgtttcgct caatataagt atggatatat tgtaaaacag
    15001 gatctgcatc ttttggctga tgctcgtaaa aattaataac ggactggatc atgtcaaatg
    15061 tttgatgaat aagcatcggg atatactttg tgaatgccag atagataagg taaacgatca
    15121 gtgtataaat catgatagct aaaacacctg tagggattcg gacaaatcgc tgaatgattt
    15181 gaacaagatg aatcatcaaa taagtaaaga taaatgtgag caaaatggtt gtaatcatac
    15241 ttctaactaa gaaaagaaca aaaacgacaa ataataaaac agtgagacgg cgtatttttt
    15301 cattcgccaa aaaacgctga taaacggtca aatcgacaac ctccaaataa caaaaaataa
    15361 acacgttatt cattatatga tggaatatga aaataagaaa gagcaaaaag aaaaaccgct
    15421 aaatgacgtt atcttatgag ttggttttcc tcataaaatc gttcatctag cagtttcagc
    15481 cctttttctg gtcttgatga aaattatcta gcatttttcg ggtcagatgt tgcagtgtat
    15541 ccaattcttc ctgttcaagt ggaagataag acttgatctt ttgtggaata ccttctgctt
    15601 gtttttgcaa cgcagcacct tgagcagtca gcgtaacatt tacgattctt tcatcacccg
    15661 tttcacgctg acgattaata taattttttt ctgctaactt ttttagtaag ggagtcagcg
    15721 taccagaatc cagacacaaa tcatttccta gctctttcac tgaagtcttt ttcttttccc
    15781 ataaaactaa catcacaaga tactgggtat aggtaagatt cagcggcttg aggaggggag
    15841 tgtagtgtct aatgatttct ttagaggcgg catataaagg aaaacatact tgattaacta
    15901 aatatagatc ttccattttt ccacctccgc tgttttacta tagtgtatca tagcggattt
    15961 acacaaaaaa gtctattcac taactgcttt cagagtaact tctatatttc cagctgtagc
    16021 ttttgaatac ggacacactt tatgcgctgc ctctaataat tcttgcgttt cttccagaga
    16081 aagaccttcg atagatcctt caatctctac acctaagaca aagctcgttt cactttctga
    16141 ataaagggaa acttgtgcac tgacagtaga agccccagag atattttttt gctgtttgat
    16201 caattctaat gcactgttaa aacatgcact gaaaccagct gcaaacaatt gttcagggtt
    16261 ggttgcattt tcgacgcgtt taccaggagc tgcaatattc aattcgaatg tacgatcggg
    16321 attatgcact tctccagagc gtccgcctgt gttgatcatt ttcgtagaat acattttttt
    16381 cataaaatta ccacctttaa ttatatttta tacaattgaa ttttacacaa tataattgtg
    16441 gaaagcaaag aaatggattg gcataagata aataagagaa agcacatgaa acagacgcgc
    16501 tttctcgaat agcaaacata tacaaaaaat atcagagaca aaaaataatc tcatcataaa
    16561 cattacatat atttctcaaa aagttgtttt ctttcttcaa aaattacttc acgatggacc
    16621 tgatgaagca tccataaata accaaaagga tctctgaaca ttgagttagt cacaccaaag
    16681 tccatcattt ctgtcatttc ttgaatctct acacagccat ttcgtaatgc tttattatgt
    16741 gtgtcctcga tatcagagac gatgatattg aaccagatcg tatttggatg ttcagcagta
    16801 ggagcagtca aaccaagaga cgtgttttca tccagcatat ggaatctcgt accatacaag
    16861 gtaaaaatga cttcattatt gcctctaggg taatctgttg cctcaatcag ttgtatttca
    16921 tcaaagattg tttgatacag ttctagtgct ttcaaactat catttaatac aaaatcgatt
    16981 tccgttcctt tatgcataaa gatctcctct ccttttcagt cgaacagtta ctagattctt
    17041 ttattatacc agctaaagaa aacgcattca aaaaaatagc ggatttactt accaactcat
    17101 tcgattggat gataagtaaa tccgcgtccc attacttctg ctacgctgct gacaatgaca
    17161 aaggcacttg gatcgatttc ttctatcaat ggtttcattc gggaaaattc atgatcagtc
    17221 acaacgatca ataaaacctc ttttgacttt cgattatacc cgccttttgc ctctagcagg
    17281 gtaaggccac gtccaatctc agcacttaag cgaaggcgga tgtcttccaa ataatgttca
    17341 ctcatgacca taacagattt ctttcgattg atacctgttt cgatataagt catgacaatt
    17401 gaagtgattg caatagataa aatagcataa agaaactctt ctattccaaa aataaacaga
    17461 ttaagagaaa caacgaatgc gtctgtaaaa aataagccaa tcgaagtatt caagtggaaa
    17521 tattttttaa aaatgagggg agggatcgtc gtaccgccgc tagaagagtt gtttttatat
    17581 aaaatcgcaa ctcctaaagc aaaaatcgca cttccaaaaa tgacagacaa caaccgatct
    17641 gaagtaatca ttgtttctgg aactattgca atgattaaag gaaaaaccaa gcttccgaaa
    17701 agtactttaa aaaagggttt tttacctaaa aatagaagag ctagtaccaa cataacgata
    17761 ttcaacacta aaataactat agctcggtca aagcctaaag cagcttccag taatattcct
    17821 agaccgctga cacctccagc agcaatatga tgaggcccta aaaacatatt gatagcgact
    17881 cctaatatga agagggcaaa aataatctta atgtatgtcc atataaattg tctcgtttct
    17941 ttcatttatt cacttcctta attcattaat aatactctta tcttattata acttactttt
    18001 caccttaagt taactttaat taataaaaaa attaggctag tctaaattat tatgtttcat
    18061 tcttctagaa tatacttcta cgccaaaaac tgttaaaaaa cttttacttt agaaaattgg
    18121 agaaattgat cgcttaagat aaattcagga cactaaatag tacaggaagt agactaaaac
    18181 ttttaaaagt tttaagtcta tctatttggc aagtttaaaa aataaaaatt cggtatcaaa
    18241 aaactgttac cgataacatt tttgaaagcg ttgtcttttg cttctctatc acttatagtg
    18301 atgacgtcat attaaaacac aaggaggaaa tcaatggata cagctgcaat ttatcatcga
    18361 ccggaaagtg aatatgcatt tctatatacg aatacaagat ttcgtattcg gcttcgtact
    18421 aggaaaaatg atatcaaaaa agtatatgtg ctatgtggag atccatatac cataacaact
    18481 gaaaaatggt atcaaaaaca acgaccaatg aaaaaatgtc taagtaccaa tgttcatgat
    18541 tattgggaaa ttgaagtgac gagcgaaaca agtcgcttac agtatgcgtt ccatgttgtt
    18601 ggggaagata acacggactg tttttacggt gatcaaggaa tttttcctta tcgagaaaat
    18661 gtgattactg aaccaaattt ttattttcga ataccttatt ttcatcaaat cgatcgattc
    18721 actattccag aatgggtaaa agaaacagta tggtatcaaa tttttcccga aagatttgca
    18781 aacggggaca aagcaaatga ccccgaacac actttacctt ggggaagtaa agatccagac
    18841 cgagaagact ttttcggggg agatttgcaa ggtgtgatgg atcatttgga ttacttgacg
    18901 gaccttggca tcaatggcat ctatttttgt cccatattta aagccacatc caatcataaa
    18961 tacgatacga ttgattatta tgaggtggat cccgcttttg gcgataaaaa acttttaaaa
    19021 aacttgattg atgaagcaca taaaagaggg atacgtatca tgttcgatgc tgtattcaat
    19081 catatgggtg tccattcacc acagtggcaa gacgttctca aaaacggaga aaaatcgatc
    19141 tataaagact ggttccacat ccgttttttc ccagtagatt cttatcagat gactgactta
    19201 ccagaaactg ctgaaaatat cccatatgat acttttgctt ttactccatt catgccgaaa
    19261 ctaaatacag caaatccaga agtgcaaaaa tatttgctgg atatcgcaac ttattggata
    19321 aaagaattcg atattgatgg atggcgtctt gatgttgcta atgaagtcga tcatcatttt
    19381 tggaaaaaat tcagagaagc agttacagaa atcaaaccag acatctatat ccttggagag
    19441 atttggcatt cctctcaagc ttggctgcaa ggggatgaat tccatgcagt gatgaattat
    19501 gcatttacag attcgattaa agattatttt gcaaaaaaga aaatcacagc ttcacaaatg
    19561 gtcagtggaa tgaatcatca gcaaatgctt tacagagatc aggtgaacga aggaacattc
    19621 aacttattag attctcatga tactgccagg atcttgaccc tttgccaagg taacaaagaa
    19681 ttgatgaagt ctgtgatggc ctttatgttt cttcaaaaag ggtctccttg tatctattac
    19741 gggacagaaa tagggatgac tggtgaagat gacccggatt gccgcaaatg tatgatatgg
    19801 gagaaggagg aacaagatct agagctattc ggttttataa aagaacttgt ttctctaagg
    19861 aaacagttgt ctaagattat ttctgaaggt tctactcagt ggctaatagt aaatgatcgt
    19921 gaagataagc tctatttcac acggaaacta gagggacaga tcatctatgt ttactttaat
    19981 cagtcaaaag aaccttgggt agtagaacag gaaaatgagg tgattcttag tcaaaattgt
    20041 cagttgttag aagacgggaa agcagagata cgacaatacg gatttttgat catgtgttga
    20101 aaactgttac cggtaacaac aagaaagcgt ttgcaaatga agatttgtgc ccattataat
    20161 aagggtgtaa cagcacgttg aatacaaagg aggaaatgaa gatgaaaaaa agaagtgtga
    20221 aacagttggg tttagggtta atctctttag gaatcttagg cggattagcg gcttgtggca
    20281 atggtaactc ttcagcagaa ggggaagccg atgaaggaaa aacgttaaca gtttccgttg
    20341 attctggata taaagattat ataaacgaaa taaaaaacac tttcgaaaaa gaaaacgatg
    20401 tgaaaatcaa gctagtagaa aaggacatgt tcgatcagtt ggaatcatta gcgttagatg
    20461 ggcctgctgg aaagggacct gacgttatga tggcagcata tgaccggatc ggtgcgttag
    20521 gacagcaagg acatctggcg gaagtaaaac tgggaaatga agcagcttac gatgaaacag
    20581 acaaagccca agtgacttat gatggaaaaa tctacggaga acctgcagta atcgagaccc
    20641 ttgttttgta ctataacaaa gatttagtcg atacagcacc atcaacgttt aaagatttgg
    20701 agaatctatc caaagacagt cgttttgctt ttgagtcaga agcaggaaaa aatacaggat
    20761 ttttagctaa atggactgac ttttattatt cctatggttt aattgcaggt tacggtggct
    20821 atgtatttgg tgatgatggc acaaatcctt cagatatcgg tttgaataat gcaggtgctg
    20881 tagaaggaat ctcttatgca acagattggt tcaaaaatgt ttggccaaag ggaatgcaag
    20941 acataaaaag tgcaggagac ttcgccagcc agcaattcat gtccaataaa actgcagcaa
    21001 tcattgacgg tccatggcaa gcgcaaacat acaaagaaaa caatatcaat tatggtgtag
    21061 ccaaaattcc tactctaaat aatggacagc cttatcaacc gtttggcgga ggaaaaggat
    21121 gggtagtcag caattatgct aaaaacaaag acctctctca aaaatggctt gattatgtaa
    21181 cgaatcagga aaatcaagaa aaattctttg aaatggtaaa tgaaatccct gcaaaccaac
    21241 aagctaggga aacagcaaag gctaaaaacg atgaattaac aacagctgtg attgaacaat
    21301 atgaaacagc tcaagcgatg ccaaacatcc cagaaatggg cgaagtttgg acaggtgcag
    21361 aaaacttgat gttcgatgca gcatcaggtt caaaaacacc aaaagaatcc gcagatgaag
    21421 cagtaaaaac aatcagtgaa gccatagaac aaaaatactg attaaaatga taaccgtcca
    21481 tttttataaa aaatggaaca ggtgcttcag ataaaagtgg caagagcgag atggaaaatt
    21541 atcttgctct tgttgccatt atcttaaaag cagtttgcgg tttagcaagt ttagaggggg
    21601 cattcagatg cagcaagata aaacaagcaa tatcaacgaa aaaaaaatca cgctttgttc
    21661 acttattcca gggatggggc agtttgtaaa tggccaagct tttaaaggta tcgttttttt
    21721 cgccatattc gtcctattca ttggtcagat gcttctgggc ggatttcatg cattggtagg
    21781 attggttact ttgggaagta taccaatgga agatcattca ttatttattt tgattgaagg
    21841 cactttgcaa ttcatcatta caatcatttt cttgattttt tacggtttga atcttttaga
    21901 cgcttatcga gtagcgaaga tgcgtcaaga gggcaaaaaa atcaatcgga cgatgaagga
    21961 agtcatacat aatataggtg atgaaggttt tccttatcta ttgacacttc ccgcttatct
    22021 tctcatgatt tttacgatca ttttcccagt cctagttaca ttgttcactg catttactaa
    22081 ttatgacttc aatcatattc caccagccag tttaattgat tgggtagggg ctaaaaactt
    22141 ttttagtatc ttctttttaa gctcatatcg taatactttt tttgcagtct tttcgtggac
    22201 cgtgatttgg actttatgtg caacaacttt gcaaatcacc cttggtattc tcacagcggt
    22261 tgttgctcac cagaaattta ttaaattcaa acgtattttc ggtatcattt tcttattacc
    22321 atgggcggtc ccagctttta ttactatcat gagtttttcg aatatattca acgatagcgt
    22381 aggtgccatc aatactcaag tgattccttt cataaaccag cttccttttg tagatatcag
    22441 tgcaatctct tggaaaacgg acccgaactg gacgaaagta gcaattatct tagtgcaggg
    22501 ctggttagga tttccctata tctatgtgat ggttacagga atcttacaat cgatttcaga
    22561 agacttatat gaagcagcaa aaatcgacgg agcaaatgca tggcagcgct tttcaaacat
    22621 cacgcttcct gctgtcttcc tagtggcagc gccaacattt attacacagt atacggggaa
    22681 tttcaataat ttctccatga tctatctgtt taacaatggc ggtcccggaa gcgtaggcgg
    22741 aggagctggt tctactgata ttcttatttc ctggatctat aaacttacga ctggaacttc
    22801 tccgcagtat tctatggctt cagcaatcac gttgattatc tccgtcatcg ttatctgtgt
    22861 gtcattgctg gtatttaaaa agacaaatgc gttcaatatg ggggattaac aatgaaaaaa
    22921 tttcattcga gtgctcgatt ccaaaaacga ctttctcact tttttactta cttttttctt
    22981 ttaatactgt cagtcattat catctatccg cttttgatca cagcaagtac tgccttcaag
    23041 tcaggaaata ttgcagcttt tagtttagat ctttcaagtg actggacttt aggaaacttt
    23101 actcggctat tcagtgaaac actttacggg acttggtata aaaatacatt gatcatttct
    23161 gtcctaacaa tgatcgtaca agtgactgta gtaactttgg cgggctatac ttatagtcgc
    23221 tatcgtttta tcggccgcaa atcaagtttg atgttctttt tagtgattca gatggtaccg
    23281 actatggcag cattgactgc cttttatgtc atggctttct tattagaagc gctcgataag
    23341 tactggttct tgacaatgat ctatataggc ggtggaattc caatgaatac ttggctgatg
    23401 aaaggatact ttgacactgt accaatagat ttagatgaat ctgctaaact tgatggggca
    23461 gggcatttca ggattttttt ccagattgta ttaccgcttg tcaaaccgat gctcgccgtt
    23521 caagcattat gggcttttat gggacctttt ggggatttca tgttagctaa gttcctgctt
    23581 cgaacacctg aaaatcagac tgttgctgtc ggcttacaaa catttatttc tgatgtgaca
    23641 aaccaaagag tctctctttt tgctgctggg gcaattttga ttgcactacc gatttgtcta
    23701 ttattcttct ttttacaaaa gaactttgtt accggcctga catctggcgg aacaaaagga
    23761 taggagcaga gtatcatgca aacatttccg ttaaactatt tttccgcatt acgtacgcca
    23821 actcaagtgt ttgcgggacg caaactatta tcatggccta aatttttctt gatatttgta
    23881 tttttagttt ccttgatggt catgcctgtg actctttttt atgccaatca gatccaagcg
    23941 attccattag aacaatttct atccgttcat tcgctgatcg atgaacaagg aacccaaaaa
    24001 ttttctgaac ttgaattatc tgaaactggg ttacaagcat cgcaacaaac gatagctgtg
    24061 acccctgaaa ttttggtagg tgtgtcttta tctgagaaac aacaatccga tcatggaact
    24121 tttattgatt ttgagaagga acaatgggtg atccaacaaa aggataaatc tggtatacgc
    24181 cgctatacga tgaattatag cccatctttc caaccagatt ctgtacgtac gcccgaagat
    24241 ttccaacgat ttttagaaag agaattttat gccagtaatc gtccaacaat cattttatct
    24301 tatagtttaa gtcttggtct tgtcctattt gtcatgacga gtctcatttt attcggggct
    24361 tcctttttct tgtggatgac aagaaaaagc caactttcat ccattcatac attcaaagag
    24421 agtgcaaatt tgatgctgaa tgttatggga ataggttcca tggcagcagc agttgtaggg
    24481 tttatccact ttgactttat cttgatgcta agtgtccaaa caacgataac tgtcttgctg
    24541 cttttatggg tttttgtcaa aacaagattc aaagataagc gtgtcgaatg acaagtttaa
    24601 gcgatttatg cgacaatgaa tgtgaaaaaa atgaaaaata aagtagtttt tgaaaaattt
    24661 ctgaaaaaat taaacttctt agttgattct tttctttttt agtattaacg taatagggta
    24721 gtttttttaa ggaggaaaat catgttagag aaaactttat acaatcaatt attttcacgt
    24781 tctttctcgc tccctgtcga agtaaattat tgggacggta caacgaaaca atacggagat
    24841 acggacactc ctccccaaat caaaatcaat atccatgaag aaatcccaat gaaagagatt
    24901 acaagtaacg cttctttggc actaggagaa gcctatatgg atcatcgaat cgagatcgag
    24961 ggaagtatcc aagcattgat caacgatgct tatcagcaag caaacagctt tttacgagga
    25021 aaagattatc taaaatggct gccaaagaaa gaaaaacata cgaaacaaaa aaacaaagaa
    25081 gatatccatg cgcattatga cttaggtaac gacttttata aactttggct agatccaact
    25141 ttgacttatt cttgtgctta tttcaataca cctgaagata cgttggaaca agcacaaatc
    25201 aataaagtcc atcatatctt agacaaactc tttatcaaag aaggcgaaac gttgcttgat
    25261 atcggttgtg gctggggaac attgatgttc actgctacca aagagtataa tgtcaaggca
    25321 actgggatca cactaagtga agaacaatac gatttgatta ccaaaagaat aaaagaagaa
    25381 catttagaag ataaatgccg tgtattatta atggattacc gcgaactaaa aggcgaaacg
    25441 tttgatcata tcacaagtgt aggtatgttc gaacatgtag gttctgaaaa tcttgaaggt
    25501 tatttcaaag tggtaaaaga tttattgaaa ccaaaaggaa cagctttgat ccatggaatc
    25561 agccgacaac aaggcggtgc gacaaatgct tggatcaata aatatatttt ccctggcggt
    25621 tatgtccctg gtgttactga attagttgat aatattacaa aaaacgattt gcaactgatt
    25681 gatttggaaa gcttacgtcg tgactaccaa ttgacattag aacattggac aaagaatttt
    25741 catcaagtcc aagatcaagt cacgaaagaa atgggtgatt ccttctatcg aatgtgggat
    25801 ctatatttac aagcttgtgc agcttcattt gaatcaagta atatcgatgt gattcaatat
    25861 ttgcttgttc aacctggaaa caatgacatc ccaatgcatc gtgcataatt gaggcaaaag
    25921 tactgtttaa agactattta aaaagaagct aagttttatg atgctccaga agtgaacttt
    25981 tttgtctaac ttctaggatt gtctctaaag cttagtttct ttttctttat attttcataa
    26041 taaaagtttg gttctttaat ttttaaacat gacagaaaat tttttcttcg ttatacttgt
    26101 aatagaatac tattttataa caaaggggat cgaatcaatg aaaaaaactg ttatttatac
    26161 tagtttattt gcagctttgt ttttagctgc ttgtcaatca aataccaatc aaggcacatc
    26221 tgggaatacg tcttccagta gcgaacagcg ctcttcacag gtatcggact cctcaacaaa
    26281 agcaagcaca tcttcgtcta gccagacaaa aagttctagt gaagcaagta ctcagtcaga
    26341 tatcaaagtg tctgcagctc gtgcgatcga attgttccaa gataaatacc cagatactgc
    26401 aattactagt ttggaattag atagtgattg gggatcttac ttctacaaga tagaaggtgt
    26461 cgatgatcaa aaagaatacg aagcaagaat tgatgctcaa aatgaaaaaa tggagacaga
    26521 gaatccagaa actctagatc gagatgaaca aaatggtcaa aagaaaaaag aagatggtct
    26581 ggatgttgat aaattgatca cgattgagga agcagcaaaa atcgccgtcg acaaagtagg
    26641 aagcggtacg gcaacagatt gggatttgga taaagattta ggtactactt attgggaagt
    26701 caaagtaaaa gacggcaatc aaagtacatc agtcaagatc aatagccaaa caggcgaagt
    26761 actgtcaact gaacaagatg attaagaatt tcttcggaaa acaagagttg atttttcttt
    26821 tagtcatgat acactagaca aaataacttg tttgaaggag cgatttactt gagtttagaa
    26881 acgacctttg ccaatcatat ctttgccaat cctttgatga atgcatctgg tgtccactgc
    26941 atgactaccc aggaattaga tgaactggct cattcagaag caggagcatt tatcactaag
    27001 agctgtacga tcaatgaacg aaaaggaaat cccgaaccac gctattttga tgttccttta
    27061 gggagtatca attctatggg acttccaaac ttaggttttt cttattatct agagtatgct
    27121 cttgcgtatg aaaaagtgca ggaaaaccaa aatcaaccgt tatttttttc cattgccggg
    27181 atgagtgtcc aggaaaactt ggaaatgctt gagaaaatag aaaaaagtgg gtttaatggg
    27241 atcactgaat taaatttatc ttgtcccaat gtgcctggaa aaccacaact agcttacgat
    27301 tttgaggcca cttatgaaac actgaaagaa gtattcagca tcttttctaa gccgctagga
    27361 atcaaattgc ctccttattt tgattttgct cattttgatc agatggctga tatcttgaat
    27421 cagtttccat tgacctatgt caatgctatc aacagtgtgg gcaatggttt gtatatcgat
    27481 acagaacaag aagcagtagt catcaaacca aaagaagggt tcggcggcat tggcggagag
    27541 tatatcaagc cgactgcttt ggcgaatgtt cgcgcttttt atacacgttt gaaaccagaa
    27601 atccaaatca ttggtacagg tgggattcgg acaggacaag atgcatttga acatctgcta
    27661 tgtggcgcaa gcatgttaca gattggtacc gagcttcata aagaagggcc ggaaattttt
    27721 tctagaatca taaaagaatt aacgcagatt atgtcagaaa aaggatatac gtcaattgac
    27781 gaatttaaag gcaaattacg caccatttca tagcaaagag acgaaggtca tgattgatct
    27841 tcgtcttttt ttataaaaaa cactcgtctg ttcattcctg tgcaagcgta ctcattgtat
    27901 gttagacgaa cttgtgggaa aataacagag gcaaaaagga ggataatatg aatgatgcaa
    27961 cagaattagc aaaagagctt aaagaaaaag aatttagttt tcaagaacta gttacggata
    28021 tacagaaaaa aataaagaag caaaatcatg aattgaatgc gtttgtcgcg cttgaaccat
    28081 tcgagagtaa ttcccacgag ctattgattc cccagtcaga aaaagggcca ttggctggta
    28141 tcccatttcc tttaaaaatg ctcggtcaag aaaaaaaggg atggctagct acttcaggat
    28201 ctcgtttatt tgaaacacac cgagcttctc atacatctaa ttatgtgcgg caagcagaag
    28261 cgataggtct agttcctttt ggacaaacca atgcgccaga gtttggtttc aaaaatatta
    28321 cagacccagt catctatggc ccagcaagaa acccttggaa ccttgaatgt acaccgggcg
    28381 gatcaagtgg aggagctgct gctgcagttt catcaggaat cgttccttta gctggtgcta
    28441 gtgatggcgg tggttctatt agaatacccg cttcgttttg cggattgatt gggctgaaac
    28501 cttcgcgagg gacgatgcca gttggtccat atgcttggag aggatggcaa ggagctgcta
    28561 ttgatttcgg cttgacagtt tctatgagag acacggaggc tttattttat gggatgagaa
    28621 gtatccattc cggtgcgcca tatcaagtat cgccagttga gtggcaaaca catccaagaa
    28681 aaaaacggtt gaagatagct ttttgtgttg attcaccgat ccactcacag attagtgaag
    28741 aggcagtact tgctgtaaaa aaagctgtag atttccttgg aaaagaaggg catgatttga
    28801 cagagattcc ttacccacta gatggtcgta aactgatcac gtcttattat cagatgaatg
    28861 gcgcagaaac agcagcaatg atccgctcga ttgaaacagg catccagcga gctgtcagaa
    28921 aagaagaact tgaacccatt tcttggactt tgttccaata tggtcagaag ctctctgccg
    28981 ctacttacat cgattctctg catgtatggg atgaagcagc aattgtcatg gaaaacctac
    29041 atcaagaata cgatctattc ctttcaccaa cgactgcatt taccgcccct aaaatcagcg
    29101 aagatttgca aagtgatgcg ataagagcac agatggaaca catcagtgat tgttctgaag
    29161 tagaaggttt agacgttgtt tcttccatgt ttgaggagag cttgaagatc acaccttata
    29221 cacagttggc taatctgact ggacaaccag caatcagctt gcctactcat ttgacaaaag
    29281 aaaacatgcc tctaggaatc caatttatgg ctgccagagg aagagaagat ttgctatttc
    29341 aaatcggcta tctatttgaa gcaaatcatc agttccattt accaaatcca tggaaatagc
    29401 agaaacaagg agaagaagaa tgaagaaaaa aagattgttt gctctaataa ctagtgcctt
    29461 ttttatttta agcgcttgcg gtacagctgc cgctaatcag gaagataaca gctggagtaa
    29521 tgtagaaaaa aagaaagaat tagtagtagc gacttctggc acactgtttc ccgcatctta
    29581 ttataatgat caaaatgaat tagttggtta tgatgtagat ttggcaaaag aggtggctaa
    29641 acggttaaat gtcaaaatct cctttaaaga atacaacgtg gatggacaaa tcacttctgt
    29701 ttcaaaaaga gaatcagatt ttgctgcgaa cgattttggt atcacaaaag aaagagaaaa
    29761 aaaattctcc ctttcagaga ctttcaaata ttcatttgac agtatgatcg tacgaaaaaa
    29821 agatgattca ggaatccact cacttgaaga tcttaaaggg aaaaaagcag ctggcgaacc
    29881 caatactagc tatatgcgtt tagcggaaaa acacggagct aaattagtca catatgacaa
    29941 tgccacgaat gatcagtatt taagcgatgt agcaaatggt cgaacagatg ttattctaaa
    30001 tgattattat ctgcagaaaa tggccgtatc tgctttacca gatatccctg taaaaatact
    30061 ggagaacgtt tatttcaatg aaaacgaaag tggtttttta ttgaaagaag gaaatgatgc
    30121 tctgaaaaag aaaatcgatg gcgtattaaa agagatgaaa gaagatggga cgacaaagaa
    30181 aatatctgaa aaatattttc aaactgatgt ttcagtcaaa ccgaaagaaa cgatggctga
    30241 gtcggtgagt gagtgatgta ctttcctcta attgattttt ccctcatgtg gacttcactt
    30301 cctttcgtac tgcaaggctt ggtatacaca ttagggattg gcttcgtgtc gtttctttta
    30361 ggaaatctgg tagggttgct tttgacagtt ttaggtcttt tggattggct gcctctgaat
    30421 gtatttattc gtttttattt atcgttcttt agaggcattc ccgcactagt cctgctgttt
    30481 ctgttatatt ttgggttacc ttatcaatta agtgccttaa cggcttcagt catctgcttt
    30541 acgattacca gcagtgcatt tattggtgaa atctatcgag gatcactagc aggcgtttct
    30601 tcaggtcagt gggacgctgg tttagcttct ggtttttctt tctttggggt attgaaatat
    30661 atcgttttgc cgcaagcttt tcgaatctca gtaccggcac tcagtaacgt agctatggat
    30721 ctagtgaaag gtacttcgtt agcagcaaca atcacagtgc cagaaatatt tcaaaaagca
    30781 aagatcatag gcggtcggac attcgattat ttttctctct atattttagt tgcactgatt
    30841 tattgggtca tttgtatcgg gatcgaaaaa gtgcaacagt atttagaaaa acgttctatg
    30901 catcagtcaa tctgaaaaat agaaatggtg ctagcgtggc tggcaccatt tctatttttt
    30961 gtttcttgta tattctgcct agtattttaa aaccatttca tgtaaaatgt aaatcgaaaa
    31021 tatgttcgga ggtagaaaac atgaagaccc cgctaaccat cgaaatagaa tcctcgttat
    31081 accaatattg catcgagcaa ggcggcttgg ttgtagaaga agtcacgatg cctgatgacc
    31141 aaggaattgt agatacgctt agctgcttga caaaatttga tggaagccga gaatggcgat
    31201 gctatgagct gaaagtgaca aaagcagatt ttcgctctac agccaaactg tcatttgttg
    31261 gacattataa ttattttgtt ttaccaagta aactatatga agaagtaaaa actgaaatcc
    31321 ctacaggaat aggtgtttta gtgtatcgtc cgtacacggt tgaagaggag atgcctgcct
    31381 ctggtacatt tctgattgcg aaaaaagcag caaagaaaga gcttgctgta ccggaagaag
    31441 ctttgacaaa ccgcttcatg gcttctttat tcagggaagt aagaaaagca aagcaaatgg
    31501 agcgaggcgt aaaatatttt ccaacagatc aattgtacaa agaattgaaa agacgttcag
    31561 aaaatcaaga tccattttct aacgaacgat attatgaacg gtttttagag gaaatagcta
    31621 gtcaggcaat caatgagttg caagaagaag ttatcgcgct tcagcatgat tatgaatatt
    31681 tgaggcaaca acagcagatc cgtcggttgc ctacagagcc attggagtga aaaatatgta
    31741 ctatccttat ttaagaggaa aacaatttga cctattagca ttaaaagaag cactgtcgcg
    31801 aggattgctc tccaataaaa tccaaccagt gatcgaacca gtacgtgatt ccgctacgct
    31861 taaaaatgtg atcgaattat ttcaaaaaaa gcaccatcca atcgctgtga tccaaaatcc
    31921 ccaagtagga caattcaaat tattcgatca gcatgtgcac agttggacag tcaaagaaaa
    31981 tagctctgtc gtccctgcac agatcttaac gccagaaaat ctcagtgaag tactggattc
    32041 acctccagcg tttcttgttt tcgatggaca gcactaccca aaagatacag aggtgtggaa
    32101 acagttggca ggagttgatt cgaaattttt gataccagat actagtcgct ttcgcatctg
    32161 gctgcccgaa aacaaaattg tgatccgtga ctcttttcaa acgagaaagc atgttgaaag
    32221 ttatgcagat aaaacagatg acttttttag tgatgactat ctttttttcc acgcagacgg
    32281 atatattgga ttttctgatt tcacgatcga aggtagccgt tatttcgata aagggttccc
    32341 tagccgagcg cttgctatcc atctaacgta tattgatgct tacggcaata tacgcgtgaa
    32401 acattttgtc tctgacagta acgactctgc taaagaccaa gcattgaagt ttcttgaagc
    32461 aggagataaa atgaaaaaat ggatcatgcg tcaccatcat caactcttga ttacttcagg
    32521 aatgattgaa ttattggctc tttaccagca acaaaaattc cctggactgg gagtgttgaa
    32581 aaagtggtca cttatgcatc atttggaact tattagtcac ctgctagatc atccaaaaga
    32641 ttggcttaaa tattattcaa aagttcagga actatatgaa gtgatccaat gattagataa
    32701 tgtaaatgaa aaaggaatag aaaagaggaa actggatgta tattcggcaa acaaggaaag
    32761 aagaagtaga agaagtggta gaaatcatta atgccgcagc ggatttcatt gcttcgcaag
    32821 gctctcctca atggcaaaac gggcagaaac caacaaaaga aacgattttg aacgatattg
    32881 aaagaaaaga aagctatgta ttaatagtgg aagatcaaat tgctggaaca gctgcattag
    32941 tctcaagcgt ggatcccgtt tacacaaaaa tagatggtag ttggaaagaa tcaactggtc
    33001 cttatttatc gattcatcgt gtcgctttag cagaaagtac tcgaggaaaa aaactagcaa
    33061 aaccgttctt agaacatttg ttgacgattg cagccagcaa aaatatccaa gatatccgta
    33121 tcgatactta tccagctaat gaaccgatgg aaaagaccat ctattctgct ggattcactt
    33181 atcaagggat gattgaattt ccttttgaac acggcgaaag aaaagcatat caaataatca
    33241 tcaattgact ataaaatcat ctgagcaaag ataaagacat taacactact gaaaaaaaca
    33301 atcatatgat agccaagagg ttgtaacaga agtggccagc ttcaaaaaac aagaaagaat
    33361 ttccgaaaat gcttctcaaa tttttgtgga attttagcgt attttacgaa atagctgctt
    33421 tctgaaactc ccttcatcga gaggtcgtga catagctttt gtcacgacct ctcggcttat
    33481 cctacgagta ttattcgata catttatatc aataatcctt tttttatttt atctgcagct
    33541 tcttggaacg ctccatcgtt tgacacgact aaaagtgagg ggatagcttt caaacgtttc
    33601 aactgtgcta aatcttctac ataaaccgcc agtctggctg aaatctgttc agatgaatct
    33661 ccacgttttt tcaggcgcga ttgcaatgtt tctttagaga tcgtaataaa gataggacgg
    33721 actaccgtcc cgaaatactc atataaatgc caaaaaccat ttgctgtcaa aacggcgtaa
    33781 caatttccta ctgtcagttt ctttttaatt tctgctttac tggaaccata tttatgttga
    33841 gcatattggt cccactctgc aaactcattt cccttgatca tctgattgaa tgtattgtca
    33901 gaaacaaaat aataatcctc ttgatctttt tccccaggtc ttggtgatcg attcgtgtaa
    33961 gtaatgatct tttgttccgg ctgaaaaata gcttctgcga gtgaagtttt tccagaacca
    34021 gaaggaccga taaatacata gcaataattc attgtcattt ctcctttgat gattgaacaa
    34081 gtgaaaaagc tttggaaaat atttccaaag cttttaaaag taactttgct tttttgtata
    34141 ttataccagc aagccagtca caatagcact taaaaagctg actaaagtcg ctgttagcaa
    34201 aattttcaat ccgtgttttg cgacaagatt tcctttttct tcatttaatc ccttcatcgc
    34261 accagaaatg atcccgatag aagagaagtt ggcaaatgaa acgaggaaga cagatataat
    34321 tgctgttgta cgctcagtaa aatggaaatt accatttgct aattctgtca tagcaacaaa
    34381 ttcatttgta accagtttag tcgccatgat actaccggca tccactgctt ctttccatgg
    34441 gattccgctg atgaaggcaa gaggggcaaa gatgtaacct aggatctctt ggaaagtgat
    34501 gccgaatatc ccgtggaaga tagcattgat catggcaatc aaagcaacaa aaccgataag
    34561 catagcagca accgtgatcg ccacatggaa accatcaaga atgtattctc ccaacatttg
    34621 gaaaaatgtc tgttctttgt tttcttcaat gatcagctca tcttcttttt cttctaatac
    34681 atagggattt acaattgaag ccagaatata accgccaaat aagttcaaaa caagggcagt
    34741 gatcacatat ttagaatcga tcagtgccat ataagatccg acgatcgaca tagaaactgt
    34801 agacatagcc gatacactca tggtgaacaa acgtttctca gataggaagg gtaattcctt
    34861 ttttatggaa ataaaaactt ccgattgtcc taaaatagca gaagctactc cattataaga
    34921 ttccaatttg cccatcccgt tgattttact taatcctaga ccaacagctt tcataaataa
    34981 tggaagaatc ttgatatagc gtagaatacc gataatagca gaaataaata caattggcat
    35041 caatacggaa agaaagaaag gtgcacttcc tttatttgct acaccggcaa aaacaaagtc
    35101 aacaccttgc ccagcaaaag caagaagatg atcaaacatt tttgccaata cagaaacaac
    35161 cgctgtacca aaagttgtac gtaataatac gaaaccaaga acaagctgta aaacgaacat
    35221 cacaattagt ggtttcaatt tgattgcttt tttgttactg ctgatcaaaa aagcaagccc
    35281 taatgtgaca aataaaccaa taatacctaa taaataactc aaataatcac tcctattcca
    35341 aattccgttt tattttacct gttttgcaaa taaaatacta atctttagtg aaattttcat
    35401 tactttttta gagtgaaacg cattcatttt ccattagaaa ataaagcgaa caaaataaaa
    35461 ggtttaaaaa gtgtaacgtc ttagtaaagt ctataaaaaa acgaaactat cgattaagct
    35521 aatagtttcg ttttcaacat ttataagtaa actttttcta ttggtaatat agattttcgg
    35581 aagggtagac aggtgcgcag gtaatatcga ttcctagttt tttcaatgtt tgttcatcat
    35641 ttttattgac catcacagta gagtgggctt gtgctccctc aagttcagct agtttatcat
    35701 aagcaacttg agcgattgga ttcgttactg cactgattga taaagcgatc aagacttcat
    35761 tgatgcttag tgcatccaaa gaggaatgaa gtgtctttga tttcaatcct tgtattgttt
    35821 caagaactaa tggtgacaat aaaggaatgt catctgcgat atgggctaaa tgttttactg
    35881 catttaagat aactgccgct gacgcatcca tcaatgaact tgtacgcccg gtaatgatga
    35941 cttcatctgg taattcgatt gcaatcacag cagaaggatc ttttgtagga ctttgcgctt
    36001 gaatcttatc tgcatagtca tgggcaggga ctaccacgtt tcggtcttca ggacgtaaac
    36061 cgacttcttc cataatcagt ttgattcgat taactgcttc ttcgtcgatc aatccttttt
    36121 tgaagtcgca ttctgtttgg aaataacgac ggatgatttc ttgtttagag gcttcttgga
    36181 caacggtatc atccacgatc ccaaatccta cacgattcac acccatgtca gtaggagatt
    36241 gataaacaga ttctttacca gtaatttttt caataatacg tttgattaca ggaaatgtct
    36301 caacatcccg attatagttc acagctactt tattgtaggc atcaaagtgg aaggaatcga
    36361 tcatattgac atcttttaga tcgactgtgg ctgcttcata agcaatgttc agcggatgtt
    36421 tcaacggaac attccatact gggaaagttt cgaacttgga gtaaccagct gcatgtcctt
    36481 tttggctttc atgatacagt tggttcaagg aagtagcgag ctttccactt cctgggccag
    36541 gagctgtcac tacaacgatt ggtttagttg tttcaatata ctcatttttt ccaaaaccat
    36601 cttctgagac gattttttct acgttgactg gatagtcttc gatttctgag tgtttataga
    36661 ccttgatgtt tcgtctttct agtttattga taaagacttt cgtggcaggc tgtccactat
    36721 agcgagtgat aacgacactg ttgattaata agccataacc acgtaattca tcgattaacc
    36781 gcaagatatc catatcataa gtaatcccat aatcaccacg gatcttatta cgttcaatat
    36841 ctccagcata gacgcaaatc agtatttcag cttgatcttt caatttttgc agcaatttga
    36901 ttttcgcatc ttcttcaaat cctggaagta cacgtttcgc atgcttgtcg tcaactagct
    36961 tcccaccaaa ttctaaatat aatttgtcat agtggttcac tcgttccaaa atatacgctg
    37021 actgctcttc aatatatttt tctgaatcaa aaccaatttt tttcactagg ttccctcctt
    37081 aagtactaaa gcattttttc atttttttga ggattcgtca actggaagag cgaaattcct
    37141 caaaaaaaca aagaaaatgg tttaaaccaa cttgtctaga tagttattca ttggtatgat
    37201 agtttttgat aaggaaggtg ctacatgaaa aaaagacaga aaaagaaaaa cgcatataaa
    37261 cactatatcc gttcgatttt taccggttat gaaagaatgc ttgaagatcc cgaattggaa
    37321 caattgacgt ttacttatct aaacgaagaa acgcagctaa ctcgtgatga gcatcagcgc
    37381 attcatttca caacaagaga tctgcctagt aaataaaaaa taagataaag gtcatcggat
    37441 tcgattctgt cctatcagat ggaaagacta gttgatcgaa aaaaaggctg taccaaattt
    37501 tggtgcagcc tgttttatgg agcattgccc gctctttttt ataacaattt tttacagaaa
    37561 atggtactat tgaagtatta ataagtgaaa aacagatgag taagaggagg caagtagtat
    37621 gaaagagcca gatacaaatg caaattatga gccagacgaa ctagaggaga cgaatgcgga
    37681 tcaggataca ggacaagaat cgtcttcttt ttacgatatc aaagaaaaag caagcatgaa
    37741 tctttcccaa ttattagaag acttacaggc ttttgaaaaa gctgtccgcg aagaagatat
    37801 ccctgagatc taccgtttat acaatggccg attgaatgaa gaattaaaaa gaagctcaaa
    37861 tgaaaatcac gagatcgatc aattgctgat gcgtaagatc catgatcgtt ttttacagga
    37921 atttcctttt atggaacaag tagaaaacat ctcgccaacg atgagctatt acaaaatcgg
    37981 cacttattac catgatcggc ccacggtcgg tattgatgca agtctgccag aaatttttgt
    38041 tttgcctaag atcgatgaag agtgggagaa atattcccaa ccggagtcaa cggactatga
    38101 caaaaaaatc aatgagctag acgcaaaggt gatcactgct cagacagaaa ttgaacgttt
    38161 agatgaacaa ataaaagaaa tcaatcgaca aatgactgat ttgaacgaca ataaaggatt
    38221 cttgaatcgt aaaaaaatcg aggaagaaat tcaagaatta gagaagaaga agcaagtact
    38281 atctaatgaa aaattaggct ggcttcctta tattgagacg cctgaaacaa tccagcagca
    38341 aaaagaagca ttgaagcaag aagcaagagc agaccagctt cgtgcagcca tcgtagaaaa
    38401 agaacaaagg caaatcagac gctatttcgg tagcaaagag ggattcggtc aagcaatcca
    38461 tgaattcttg atgaattatc ttggcaatga gaatcctaat aatcaatcta atgaaggagg
    38521 ttccgagtat gaatgaacac gatgaagcag aatggacaaa aaatgaagaa caaacagaag
    38581 atcatgaaga aacgaacact tcattggaag aacaaacaag taatcctctg gatgacacag
    38641 aagaaatccc tatgctagag gaaacaaaaa tacacgaaaa agaaaaagta actccgacga
    38701 atacgaatac tgcagaaaac acccatgctt acgaaataac tgaaaatccc gggtatttag
    38761 aaggaaaaga gcaagatcat caagatatcg tcagtttgat tgaaacagcg gaagcagaat
    38821 tagcggattt acgtatgaga aaagatttga tcgaatcaga ttttccacaa ttattagaat
    38881 catatgatcg ttttatattg aatgaagaac caatctccac gatcggaaag acaagcctga
    38941 tcgaatactt cacgtatgaa ttactgaaac cgttgaatga tattggtctg gaacggtcaa
    39001 attcagctta tgacacatgg aaaacaagac atttttcgat caattatacg ttgaatggac
    39061 aaaacgaatt agtcttttcc tttgtattac cgaccatcga tcaacgatac caagtggaat
    39121 cgatgagtct cctaaacgta tcaccagaga caatggaaat caatgtccaa gatgaccggg
    39181 tgctttcttt gatccgacac tggtcagtgg atcgagtatt ctctgcaggg cagatcacga
    39241 tattcaatca caaattgaat caattattag cccatgcaag aacacttggt tttaccgtta
    39301 atcagacatt actagacaat acgaagccac ttcgtttgaa tcttcagagc gaatttgaat
    39361 tgacgaatga agtattggat gatattttta tcgtggcaat gaaaaatcca tcctacgata
    39421 tggaaaagat caacgaaact acttatcaag tacgattaga taaaggacag tctttaacga
    39481 taacaacaaa cgaaaaagat caaacagtct tgtcgatctc atctggagac tacccacgat
    39541 ctgtcattga tttctttatc aattacgaat tcttggtccc attaatggtg agaaagtcct
    39601 gattggataa gttggattac cagatgtcat tcagataatt ctgttccaaa ggacttgcgg
    39661 cagttatcca gaataattgt cacaagtctt ttctgtatgt actaaatgga cgtgaataac
    39721 ttgctgatga aggagggatt tcattaggaa tgtccacaaa taaaatagca cagcttagct
    39781 tattgtctgc tgcttgtgta gcaggtagga tcgcttttca atttattccg aatttccagc
    39841 caatgactgc tattttttta tttatagtac tttacttaag cttaaaagat gcgttaattg
    39901 tcatgagtct ttctattgcg atcagcagtt tttattttgg tgttggacca tgggtcatcg
    39961 gccaatggat cagctatact gttgttctga gtttgttttc aatcgtctgc ttgagaaaaa
    40021 cagtgcaaag gaatctatgg ttaaagggag tctgtttttt tctggcgggc atggtttacg
    40081 gaataggtat gaccgttttt gatacgctgt tatatcgttt gcctcaacct tggatctatt
    40141 accttcaagg ggtgtcgttt gatttgatgc acagtatagg caatgttgtg ttctttcttg
    40201 tttttctgcc agtcgtcaaa cgtttttaca atcattcagg aggaaaaaat gaaaaaaata
    40261 atttatagtt tgcttgcaat gagtgtcagt atactcattt tgacaagttg cagtacaacc
    40321 tatacacaat cggcttccaa ccaaaaggag gaagtaaaaa catcgcaaaa agcaacaatc
    40381 acgttacaag aaaatggtca aaacttttcg gaaaaagaag tgttcttcaa aaaaggcgat
    40441 gatttactga gtattttgaa acgaaatttt gaagtcaaag aagataacgg cttcatcact
    40501 tcgcttgaag ggcactcaca ggatgagaaa aatcaactct attggatgtt tactgtggac
    40561 gggaaaagtg ctactactgg tgccaaagag atcaaattga atgatggaca atcggtcatt
    40621 ttcaatttgt ctaaactata agtttcataa aaaactgtta aagggcgaat attgccataa
    40681 ttcagtgagt tcagttgatg aaagaaggaa aataacatgg aaaattttaa aaaaagcgga
    40741 atgttttccg taattgctgc tctaggggct aatattctag ttgctatcag caaatttgtc
    40801 ggctatgcaa tcagtggcag tgccgccatg ctaaacgaaa gcatccacag tatcgttgat
    40861 tgcagcaatc agattttgct gttattcggt gataaacaag ccaataaagg acagagcgag
    40921 ttgcatcaat ttggtgaagg acgagcaaaa tactttttca gtacaatcgt cgcaatgatg
    40981 cttttcttcg gcggtggggc acttggggtg atggaagctt ttgaaaagtt gacgcatcca
    41041 tcccatgaag tgggtaatcc gatcattgtt atagcaatac tgttatttgg tttggtaatc
    41101 gaaggaagtt cgttacgcgt ggcaatgaaa gaaatcaaag aattgaatac tgaaaaactt
    41161 tccacgatgc gctttttgcg cgaaagtcga cacagtgaaa tactgattat ttttacggaa
    41221 gacttgtgtg ctgtaatcgg tttggtcttg gctttagcag gaacaatatt gacttatgca
    41281 accgggattg ctgcatttga tgcgatcagc ggattgctga tcggtttctt gctgatggga
    41341 gccgccattt tcctagcaaa agaattttat agtctgatca tcggtgaaag cgtgacagca
    41401 agcgatttat caaaaatcaa gttagctttt gaacgtcctg agatcagtcg gctgatcgat
    41461 ataaaaacag ttcatttaag tccaacggag attttagttg cagcaaaagc agatatcgtt
    41521 ggtaacaaag agaatgaagc ttactcggtc atcaatgata ttgaaaaaaa tatgcgtcag
    41581 tctcttcctg acaagaagat gtatatatac attgaaacag ataaatatga cccaaattat
    41641 tctcgtaaat aaaacgttta ttcatgaatt gaagcaaaaa tgagaaaaat ataatcttgt
    41701 ttttaaataa aacggctaca atttagcgaa tttatgttac aatgagtccg ctgtttattt
    41761 gttgtaatta aaggagatat tttaatgaac aaaaagaaaa gtgcgccatg gcttcaagct
    41821 ttgcatgcag tgatgccact ttgtataagc tatataccag taggattagc ttgcggagta
    41881 ttgttgcaaa aagttggatt tgatcctctc ttatcaggac tgttatcgat tctggtcttt
    41941 tccggtggcg cgcagttttt agttgcatct atgcttacga cgcaagcatc atttgcaacg
    42001 acattattga tggttttctt tttagaatta cgctatacat tattaggagc aagtcttgcc
    42061 ggttttatga aaaaagaaaa gcggacgttt ttggctgtct tttctcaatc actgaatgat
    42121 gaaaactatg cggtgaacta cttaaagttt tcaactgacc cttcctggaa taaaagaaag
    42181 gctttatatg tcaattggtt ctcaatgact gcatgggccg gtagcaatat gatcggtaat
    42241 tttttcggct cggtgattcg agtagatgct gaccttgtcc attttgcttt gacggccatg
    42301 ttcattttca tgtttatcat gcagatgaaa agcgcactac tgatctttac aggtttattc
    42361 tcaggcgtat taggggtcgt attcatggta ttattccaaa atactttcgg attgattgca
    42421 gcaacagtca ttgcttcatt tgccggattt atgctggaga aggcattcaa aaaagaaaaa
    42481 gctaagaaac taagagaccg cggtaaagat gtcaatgagc cgctcttcaa cttcccggaa
    42541 caggaggcca atcaccatga ctaaactata tttgctactt ttagttgctt gtctgttcat
    42601 cgtggcatat atcccgcgct tgttcccgat gctttatttt actcatcgaa aagtgccatc
    42661 ctggttcagt gactggatga aatatgtacc ggtggcatta tttgcggcgt tagcttttaa
    42721 agatgttttc attactcatg aacatctgga tattgcttgg aatatcaaaa tagctgcaat
    42781 gattctagta gcaggcgtgg cttacaaaac acgttcgatg gcgttgtcag ttttgacagg
    42841 acttgcgtct gtctttttgc tgtctatgct ttaaactgtt ttattttatt aaaaacagag
    42901 attgcgacat aagttgttca aactgatcta tccgaactgc atttgcaaca gtcaattctg
    42961 gatgcaagtt tattcgtagg gataaaaaag attagtgttg gcttatgatg caagctcttt
    43021 tttattttag gaattagaga gggatttgtc cttctatgat tttttgctat aatagggaag
    43081 atgtttattt tatgaaagaa tagttgaggg aatttaaatg aataaaaaat tgatgcaagg
    43141 aacattttgg ctaacctttg ctaatcttct atgtaaagtt ttaggggtag tctatttgat
    43201 tccctggcta agtatgatgg ggaacaatca agatggtatg cttgctacga cattgtataa
    43261 tgttggctat cttccttatg gattgttcct gatgcttggt acagtcggat ttccaaatgc
    43321 gattgcaaaa aaagtagctg tagccacaaa agaaggagat aacgctgctt gtcggctgat
    43381 ttttagaagt acgatcaata tcatgtttgt catcggtatc gcctctgctg cactgatgta
    43441 tttatttgct cctttactag ccggaatcag tccgattgct aacgttaata atgggatact
    43501 agctatcaga agtttatgcc catctttgat tgctatccca attcttagtg caatgagagg
    43561 atatttccaa ggaaaaaatg atctgcggcc ttatggaact tctttgatta tcgaacaggc
    43621 tgtgcgagtg atcgttatct tggctggtac ttattacttg cgcgtattga ctgacggaac
    43681 catattagaa gctgtattga tcagtacagt cgcttctttc ttcggtgggt tagctgcgat
    43741 tatccatatg tatatcgtcg gacgcagaaa agacttcttc gaacttaaag attttttgat
    43801 ttccagccgt tatttcgaaa gagaaaaccg atctgcctct gtctctatca ttcgggaaac
    43861 actaccgttt atttttgtcg gctcagtcat tactatcgtt caaatgatcg accaagtaac
    43921 gatgaaacca ctgcttcact ttttccgtcc agagatcgca gatcagcaac tggaattctt
    43981 attcagccgt gcttctgtca atccaaataa attgacattg atcctgatct ccatggtagg
    44041 aacagtagct ataagcagct tgccaatatt aagcacgatg aagaaaaaag atcggataca
    44101 aatcgaaaaa acagtaggag atagtttttc gattgcgtta ttgattcttc ttccttcatt
    44161 gactggaatg tctttattag ctggaccact atacacattg ttttttggct atgatcctga
    44221 aagtgtcgga tatttccaaa tggctttgct agcttctttg tttttctctt tattcacgat
    44281 cctatctacg atgcttcaat ctttgaatca ccatcgtttt gcgatccgat taactgtaga
    44341 agcaattatc ctgaaagtca tcttccaagt aatcggatta ggattagttg gcggatacgg
    44401 gatgagctta tcaaatggct tagcattcgg tattgtcttt gttcgcggct atcactttat
    44461 gtgcaaagaa taccgaatag cacctttagc aaagatcagc aattttttct taaaaacttt
    44521 ccgctccacc ctgattatgc ttgcagtatg ttttgccgtt ttctttttgc tgaatcagcg
    44581 attgtcaatg gaatcaaaaa gctatgcaat gatttattgt gtggctgtag gaagtattgg
    44641 cggcttagta tttttatttt ctcaattcgg aaaaaatggg tttcgaatgt tgaaaaatgt
    44701 taaacatcat agcagaagca aagaataggt taactaatcg ttttttgctg tcacttgaaa
    44761 aacggcaact cgtatgatta cgcttgtcgt ttttctattt tccaatttta gtttcatatc
    44821 taatcttact tatgatatag ttataaggtc tggaaaaatt ctttgaaacg aggaaattaa
    44881 acacatgaaa cttgcagtag ttacagatag ttcggcatat ctgccggaac gtatcaagaa
    44941 ccatcccgac ttattcgtta ttccaatccc tttgattatg gatgggaaaa tttataacga
    45001 aggaatcgat atcgaagcgg atgaatatta tggactttta aaaaacagta aagattttcc
    45061 tactacttca caacctgtcg taggggaagt tttgggttta tatgaggaat tgaaagagaa
    45121 agggtatgac acgattttaa gtatccatct ttcttcaggg atttctggct ttgtcaacac
    45181 attatttgcg atgaaagatg acatcagcgg agtaacggtc attccttatg actctaagat
    45241 cactagtatg ccgatgggac acatggtaga agctgcctta gacttaaatg atgaaggtca
    45301 gtcccttgat gaaatacttg cacatatcga tcgaatccga gataatacct acgcttatct
    45361 gattgtagat gatttgaaca atttagtacg aggaggacgt ttgacaaatg gtgcagcgct
    45421 gattggcagc ttattaaaaa tcaaaccgat cctgacattt tctgaaggga aaattgtttt
    45481 attcgaaaaa atccgttcaa gtaaaaaagc atttgctcga gctgaagaaa ttattggtag
    45541 aagaaataac gaaatacaac cgccagtcaa actttacgtg atacatgcaa ataatttaga
    45601 agtagcgatt gcggagaaag agaaattgca gaaaaaatat ccaaatgcag aaatcgaaat
    45661 tggtcatttc ggaccagtca ttggtacaca tttaggtgaa aaagccatcg gcattgccat
    45721 ttcagcgcaa taattccttt tattcaaaaa acataccaaa aatattccaa catcatcttg
    45781 gactttctac atgttactaa tgagcgtgta aaagaacgag atggtgtttt tatttctatc
    45841 aatgaagctc tttttctttg caatcctcac ttcaatcctc tataatgtcg catatagttt
    45901 agtaaatgag taaactacta atttacttat ttactaaaaa taaaaggatg aggagttaaa
    45961 ataatggaaa taccaacaaa tttaaaacat aaaccagtaa tcgttgtaga agactatgat
    46021 aaagttgatg gaagaaatgc attaaatacg gatgcaaaag ggctttcact gggccttgct
    46081 cagtggaatg atcgtggaaa agtcgatatc tcaggcaagg tatggcgaca tactggagaa
    46141 aaatggtcac gacagtcgga agaattacca atcacacgta ttttagattt agcgatctta
    46201 gctgcacaag gaagtttata cttccaagat gcttatcgtt atgaaaaatt ttatgatcca
    46261 gaaaatccag tcgtagacat cattggatta caagggaacc gaatgacggt agaagtagat
    46321 accaaaaatc caaagatcga tgaagacatc attttgtatt acgatacact acaaaaagac
    46381 ggagaactga ttggggaacg attccgtatt ttaaaacgtc ttttagatga gctaggatat
    46441 taatagacag agatgatcaa aaggggaaga gaagcatgga gaatttctca ctaacagaaa
    46501 accgaacctt ttcacggcta gaaaagcaaa tgatctggaa gaaaccgaaa agccatcgga
    46561 caagtgcaga agaatggcgg atcgcctccg aaatcaaagg gaattggcaa gatcctgaaa
    46621 tgaaaatcag taacgtactt ttggaaggag atgccgggtc ggggaagaca caattagcca
    46681 aagcactatc tgctgatctg caacttccct atacaaaagt gacctgtttt gcagatatgg
    46741 acaaatcaga tgttttcgga gccttattac ctgtagtaga ttctaataag gaacaagacc
    46801 aagaattact agaagctatt taccaaacag atacacttga agctgtactg acactgatcc
    46861 agaaccatta cggcattgat cctttttctg ctaaagaaaa attagcagag ctagttcaaa
    46921 ggatcgaagc tgattatcca gatgcaatcc attacagcta ttacccttct gaaatcgttc
    46981 gagcgattga aaaaggatat ttattagaga ttcaagagcc gactgtcatc cgagatgcct
    47041 ctgttcttgt ggcacttaac tcagcgctcg aaccaaatgg gatgttgaat ttaccgacag
    47101 gaatcattcg tcgccatcca gattgcgtca ttgtgatcac tacaaatcga aattaccaag
    47161 gaaatcgccc attaaatgaa tctttaagag atcggatgca acatgcggaa aaaatggatc
    47221 ttcctgcctt agaagtcatg gcagaacgtg cgatggcgaa aactatgatc caaaaacaag
    47281 aacttctctt aaagatggca gagattatcc gtttgttgga tgaaactgca aaagctaacg
    47341 ccatcaaagg tgtagcagga atgcgttctt atttttattg ggcaaatacc tataagcaag
    47401 gacaagattt actccagtcg atttatccaa aagttttgta taaattatcc actgattcag
    47461 atgaattggc aattcttgaa caagctttgt ctgacagtgg attgctactg gaacttcagg
    47521 acatattgag aaaagaaaaa tggggtcatc ctcaatctga gcatacaaaa ggaagaacca
    47581 ttagcgccga agaagcaaat gaacgaaaca tcactgaaaa tgctgaagaa attctgcgct
    47641 tagatgaaaa gaaatcgttg tctgctgaag aaccaaatga gggagaagag aaacaagaag
    47701 aaacaataga aaaaaacgag attcctcctc aaatgcaaaa agaacgcagt agcgatatcg
    47761 aaggaaaaaa tcaaaaagaa caacaaacag gagatgattc tcaagaaatg tctgcttctg
    47821 acatggaagc acatgataag gaaatcaaga agcaactgaa taaagaagcg cgacaaatca
    47881 tgaaggaaac gattcatgaa aaagaaggtc tcatcgttca ccgaccagct ttccaaggaa
    47941 aaacgccgga agcacgtgag ctacacatgc aagtaatgcc aatagtagaa tcacttagcc
    48001 ggcaaatttt agagttactg gataatgaac aaacagagac gtaccaaaaa ggaaaatacg
    48061 aaggtcagcg gttcaatgca agcaaagtag catatggtga tttgagaaat tttgacaaaa
    48121 agaacccgcc acatgagcaa ccttctttag cggtagctgt acggatcgat gaatctgggt
    48181 caatgatacg ggatgatcgg atcgaagcgg caaaaaaagc agcgattgcc attgccgaat
    48241 tttctaagaa agtcgatatc ccattgttga tttacggaga tacagcagac cgttcgtcaa
    48301 gagaaaagac ttctttgttt tcttataaag aatttgaaga cggatttcaa tggttaaatg
    48361 aaaaattagt cactatgaaa ccaaggcaaa acaatcgtga tggtgctgca cttcgtttag
    48421 cagcagaaaa attaaacaga caatccgcaa caaccaaact gttgcttaat attagtgacg
    48481 gtcagccaaa agcgttgccg gattatacag gcaaaaaagc aaaagaagat atccagtctg
    48541 ttttgaaaga atatgaacgt caaggaatcc tatttgtctc cgcagctatt ggccaagaca
    48601 aagaagaaat caagtcgatc tacggtgaaa gtcgttttgt agatattact gacttgaatg
    48661 aatttcccaa gcaaatgatt caactgattg cccgctatct atgataaaat aaagctcaac
    48721 gaacgcactt agcagattcg ttgagctttt cgtttctagt taccggtaac aaggatactt
    48781 ctaaaataga atcggttata atcaagaggg accgttaaag gagtgaaacg atatgataca
    48841 agaacaaaaa tggtggaaag aagcagtagg ctatcaaatc tatcctgcta gtttcaaaga
    48901 tagcaatggc gatggtcaag gagacatcaa tgggatccgt gaaaaactta attatttgaa
    48961 agatcttggt atcggcttta tctggatcaa tccgatctat caatctccat ttgtcgataa
    49021 tggttatgac gtaagtgact atcaagatat agaagagaga ttcggaacga tggaagattt
    49081 tgatttattg ctaaaagaag cacatgaatt agggatcaaa gtgattatgg atcttgtcat
    49141 caaccatagt tcggatcagc atcaatggtt tgaagaatcg aaaaaatcta aagaaagccc
    49201 gtatcgcgat tattacattt gggtcgacgg ggtagatggc aaagaaccga ataattggac
    49261 atcgattttc ggcggttctg cttgggagta ttctcatgaa actggacagt attatctgca
    49321 tgtttttgca aaagaacaac cagacttaaa ttgggaaagc gagaaattga aagaagaact
    49381 attcaatatg atccgatggt ggttggataa agggatagat ggatttcgtt tagatgcgat
    49441 ttctcatgta aaaaaagatg aatattcagt aaaagccaca gagaaccctt tctcaccctt
    49501 tcaaaatgtc tcaggaatcg aagaacattt gaccgatttg aaacatgttt ttgaagagta
    49561 cgatatcatg actgtcggag aagcaagtgg tgtcactgca gaagaaggac cacaatgggt
    49621 agggaaagac ggttatttcg atatgatatt cgaatttgat catatccata tctggcagca
    49681 agaaaaagaa gggcaattag atgtccttaa attgaaactt gcattaagcg cttggcaaac
    49741 ttcattggat ggtatcggat ggaacgcttt atatatggaa aaccatgatg ttcctcgtgc
    49801 cgtttcagtg tttggagata ctcgtcccga tttttgggct atgtctgcaa aagcaatcgc
    49861 tatgatgtat ttctttttgc aaggtacgcc atttatttat caaggacagg aaatcggaat
    49921 gacgaatatg ccctttgaat cgatcgatca agttgatgca gtagattcga aaagacttta
    49981 taaaaggctg cttgcggaag gtaagacaag agaagaagca ttggatatca ttcgtgaaac
    50041 aacgagagac aacagcagga cacccatgca atggacttcg gaacaatatg ctggtttttc
    50101 tacacatgaa ccttggctga tcactaatcc aaataccaaa acgatcaatg tagaacaaca
    50161 agaatatgaa ccagagtcgg tcctgcaatt ctataagaac atgatccgca ttagacaaac
    50221 caataaaggt ctgatatacg gttcttataa agaatatctt catgaacatc cacaacttta
    50281 tgtctatgaa agatatttag aagatgaaca atatcttatt atggtaaact taacagaatc
    50341 acttgctgac tatgaacttc caaaagaagc agatcagtcc tggacattac tcttgtcaaa
    50401 ttcctctagc ggagaatttg aagctaaagg catactagca ccttatgaag ctcggttata
    50461 taaaacaaac aagtaaaact tcctcgttaa agttcattag ttggactttg cgaggaagtt
    50521 tttcagattg ctctgtcaat tactcatttc aataattcgc tctaggacca ccgatatatt
    50581 taggacgaga gcgaagggct gtcacgtgag cttgtccaag ggttttcaaa cgaggtctga
    50641 caggtacttg gacatgtttg atatgcatac cgattgatgt gtcaccgata tcgataccgg
    50701 cttgtccaac tacgtgttcc acttcgacag gatcattgaa ctggtcaaaa gcagcaacag
    50761 aacaagcacc tccagcatgt agtgcaggaa caacagagac aatttcgaaa ttttttgctt
    50821 ctgccactgt tcgttctact actaatgctc ggttcaaatg ttcacaacct tggacagcta
    50881 gcgcaatttc tttaggatcc aacaactctt ttaacgtacg gatgatccat tgaccaactt
    50941 ccgcactgga attttttcca atatgtcctc caacgacttc gcttgtgctg catcctaaaa
    51001 caaaaagatc accttttttc aagtgtgcct cagccaatat gtcattaact atttcagtca
    51061 attggtcttt taattctttt tctgacaact tcattttcta aaaccttctt tttcaattaa
    51121 tattgcttcc gtgcttgaat acgttgaaga cttgcagtta taggaaaggc aagtcccatt
    51181 ccaatcagat tttggaagat gtttcctggt atagaagcca ctccagccgg ccaatcatat
    51241 aaaatccaac cggcgatacc atagccgatg atcataacta agcttcctaa taaaagccct
    51301 aatccccaca tacgagtaga agatttgctg aaagaaccag caacatatcc ttgtaacccg
    51361 tggatcacta atgaaaaaac tgcccactgc ggatatcctg aaatcaaatc gatcaataga
    51421 ccactggaag caccaacaac taatccaccc gttggaccat aaagaaaagc agcggtatag
    51481 atcccggcct cgcataatgt cacaaatcca ttcgtagccg gtacagggat caaaattgtt
    51541 aatgaaaggg caactgtcaa cgcaatcagc atagcataga tcgttaattg cttagttttc
    51601 atttctcatt cctccttttt gaataccgcc agaccagaca cttccggtat gatcgttcat
    51661 cagcacgcca ttagaaatac aatgggcaac aaatttttta ctttctgcta ctgctttggt
    51721 aaaatctgcc cctaacacaa gattcgctgt tattgcagaa gaaaaggcac aaccggcccc
    51781 gtttactgtt gtagtgtcga tttttttatg agaaaatacc tcataatgat caattgaata
    51841 gagaagatcc acagcttcat ctccagccat ccttgtgccg cctttgatca caatgttttt
    51901 tgttcctgaa gcagtgagtt ctttagcgag atggatcatt tctgttaacg aagagggaag
    51961 agcttgacca gaaagtaaag cagcttctgc caaattaggc gtaatcatcg taacaagtgg
    52021 aaaaagttct tcgatgagct gcgaaatata caattgattg atcacagctt cagtttcttt
    52081 gaatgccaaa acagggtcta aaatgattgg gatattttgt tttgttttta tgaagtctcg
    52141 aacaaccatg attgcttcac ttgaattcaa taacccaatt ttgataccat ctaatgaagt
    52201 cattttatca atcgaaacta actgtcgttt aagcaattcc aaagatatag attccagcat
    52261 aaatcgctca ttaatatcta gtgcccctat agaagtcaag gcgcttagtc cgaatagacc
    52321 aaaattctca aaagttttta aatctgtttg gattcctcca ccagcaaatg gatcagaacc
    52381 gccaattgtc aagattcttt tcataacatt ttcctccatg aataagagta taacgaaatt
    52441 ttcaaaaaag aaaaacagcc aattggcata tttttatctc atccaattta aaaaaacaaa
    52501 aagaaaagaa agaccaaaat ggatctttct ttccttaaat a
//
LOCUS       DAZKCW010000014        52448 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000014 DAZKCW010000000
VERSION     DAZKCW010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.014"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..793
                     /locus_tag="ACG84Z_000901"
                     /pseudo
     CDS             1..793
                     /locus_tag="ACG84Z_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
     gene            933..1859
                     /gene="cysK"
                     /locus_tag="ACG84Z_000902"
     CDS             933..1859
                     /gene="cysK"
                     /locus_tag="ACG84Z_000902"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFP9161762.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2095..2541
                     /locus_tag="ACG84Z_000903"
     CDS             2095..2541
                     /locus_tag="ACG84Z_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFP9161763.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2813..4165
                     /locus_tag="ACG84Z_000904"
     CDS             2813..4165
                     /locus_tag="ACG84Z_000904"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFP9161764.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            4336..4623
                     /locus_tag="ACG84Z_000905"
     CDS             4336..4623
                     /locus_tag="ACG84Z_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFP9161765.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            4849..5292
                     /locus_tag="ACG84Z_000906"
     CDS             4849..5292
                     /locus_tag="ACG84Z_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFP9161766.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5298..6482)
                     /locus_tag="ACG84Z_000907"
     CDS             complement(5298..6482)
                     /locus_tag="ACG84Z_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFP9161767.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6750..7448
                     /locus_tag="ACG84Z_000908"
     CDS             6750..7448
                     /locus_tag="ACG84Z_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFP9161768.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7455..8132
                     /gene="nth"
                     /locus_tag="ACG84Z_000909"
     CDS             7455..8132
                     /gene="nth"
                     /locus_tag="ACG84Z_000909"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFP9161769.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8258..8791)
                     /locus_tag="ACG84Z_000910"
     CDS             complement(8258..8791)
                     /locus_tag="ACG84Z_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161770.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9088..11469)
                     /locus_tag="ACG84Z_000911"
     CDS             complement(9088..11469)
                     /locus_tag="ACG84Z_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFP9161771.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11459..12106)
                     /gene="recU"
                     /locus_tag="ACG84Z_000912"
     CDS             complement(11459..12106)
                     /gene="recU"
                     /locus_tag="ACG84Z_000912"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFP9161772.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12170..12709
                     /locus_tag="ACG84Z_000913"
     CDS             12170..12709
                     /locus_tag="ACG84Z_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFP9161773.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12799..13218
                     /gene="gpsB"
                     /locus_tag="ACG84Z_000914"
     CDS             12799..13218
                     /gene="gpsB"
                     /locus_tag="ACG84Z_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFP9161774.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13240..13607
                     /gene="rnpB"
                     /locus_tag="ACG84Z_000915"
     ncRNA           13240..13607
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACG84Z_000915"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13816..14982
                     /locus_tag="ACG84Z_000916"
     CDS             13816..14982
                     /locus_tag="ACG84Z_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFP9161775.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15028..16524
                     /locus_tag="ACG84Z_000917"
     CDS             15028..16524
                     /locus_tag="ACG84Z_000917"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFP9161776.1"
                     /translation="MKEKEFLQEVKEINLLQKALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16605..17288
                     /locus_tag="ACG84Z_000918"
     CDS             16605..17288
                     /locus_tag="ACG84Z_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFP9161777.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            17933..19123
                     /locus_tag="ACG84Z_000919"
     CDS             17933..19123
                     /locus_tag="ACG84Z_000919"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFP9161778.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19225..20178
                     /locus_tag="ACG84Z_000920"
     CDS             19225..20178
                     /locus_tag="ACG84Z_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFP9161779.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20247..21596
                     /locus_tag="ACG84Z_000921"
     CDS             20247..21596
                     /locus_tag="ACG84Z_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFP9161780.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21779..22102)
                     /locus_tag="ACG84Z_000922"
     CDS             complement(21779..22102)
                     /locus_tag="ACG84Z_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161781.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22231..23394
                     /locus_tag="ACG84Z_000923"
     CDS             22231..23394
                     /locus_tag="ACG84Z_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFP9161782.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23464..24813
                     /locus_tag="ACG84Z_000924"
     CDS             23464..24813
                     /locus_tag="ACG84Z_000924"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFP9161783.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(24858..25289)
                     /locus_tag="ACG84Z_000925"
     CDS             complement(24858..25289)
                     /locus_tag="ACG84Z_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9161784.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25677..28319
                     /gene="alaS"
                     /locus_tag="ACG84Z_000926"
     CDS             25677..28319
                     /gene="alaS"
                     /locus_tag="ACG84Z_000926"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFP9161785.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28519..29115
                     /locus_tag="ACG84Z_000927"
     CDS             28519..29115
                     /locus_tag="ACG84Z_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFP9161786.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29237..30385
                     /locus_tag="ACG84Z_000928"
     CDS             29237..30385
                     /locus_tag="ACG84Z_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFP9161787.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30423..30836)
                     /locus_tag="ACG84Z_000929"
     CDS             complement(30423..30836)
                     /locus_tag="ACG84Z_000929"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFP9161788.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            30915..31346
                     /locus_tag="ACG84Z_000930"
     CDS             30915..31346
                     /locus_tag="ACG84Z_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFP9161789.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31445..31678)
                     /locus_tag="ACG84Z_000931"
     CDS             complement(31445..31678)
                     /locus_tag="ACG84Z_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9161790.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            31861..33531
                     /locus_tag="ACG84Z_000932"
     CDS             31861..33531
                     /locus_tag="ACG84Z_000932"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFP9161791.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33678..34064
                     /locus_tag="ACG84Z_000933"
     CDS             33678..34064
                     /locus_tag="ACG84Z_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161792.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34051..34749
                     /locus_tag="ACG84Z_000934"
     CDS             34051..34749
                     /locus_tag="ACG84Z_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFP9161793.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34754..35218
                     /gene="lspA"
                     /locus_tag="ACG84Z_000935"
     CDS             34754..35218
                     /gene="lspA"
                     /locus_tag="ACG84Z_000935"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFP9161794.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35215..36126
                     /locus_tag="ACG84Z_000936"
     CDS             35215..36126
                     /locus_tag="ACG84Z_000936"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFP9161795.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36361..36900
                     /gene="pyrR"
                     /locus_tag="ACG84Z_000937"
     CDS             36361..36900
                     /gene="pyrR"
                     /locus_tag="ACG84Z_000937"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFP9161796.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            36914..38197
                     /locus_tag="ACG84Z_000938"
     CDS             36914..38197
                     /locus_tag="ACG84Z_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFP9161797.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38210..39136
                     /locus_tag="ACG84Z_000939"
     CDS             38210..39136
                     /locus_tag="ACG84Z_000939"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFP9161798.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39155..40435
                     /locus_tag="ACG84Z_000940"
     CDS             39155..40435
                     /locus_tag="ACG84Z_000940"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFP9161799.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40440..41516
                     /locus_tag="ACG84Z_000941"
     CDS             40440..41516
                     /locus_tag="ACG84Z_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFP9161800.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41521..44706
                     /gene="carB"
                     /locus_tag="ACG84Z_000942"
     CDS             41521..44706
                     /gene="carB"
                     /locus_tag="ACG84Z_000942"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFP9161801.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44760..45536
                     /locus_tag="ACG84Z_000943"
     CDS             44760..45536
                     /locus_tag="ACG84Z_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFP9161802.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45533..46465
                     /locus_tag="ACG84Z_000944"
     CDS             45533..46465
                     /locus_tag="ACG84Z_000944"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFP9161803.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46462..47178
                     /gene="pyrF"
                     /locus_tag="ACG84Z_000945"
     CDS             46462..47178
                     /gene="pyrF"
                     /locus_tag="ACG84Z_000945"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFP9161804.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47185..47814
                     /gene="pyrE"
                     /locus_tag="ACG84Z_000946"
     CDS             47185..47814
                     /gene="pyrE"
                     /locus_tag="ACG84Z_000946"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFP9161805.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47802..48116
                     /locus_tag="ACG84Z_000947"
     CDS             47802..48116
                     /locus_tag="ACG84Z_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161806.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48154..48795
                     /locus_tag="ACG84Z_000948"
     CDS             48154..48795
                     /locus_tag="ACG84Z_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFP9161807.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            48838..49530
                     /locus_tag="ACG84Z_000949"
     CDS             48838..49530
                     /locus_tag="ACG84Z_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFP9161808.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49527..50429
                     /locus_tag="ACG84Z_000950"
     CDS             49527..50429
                     /locus_tag="ACG84Z_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9161809.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50587..52293)
                     /gene="efbA"
                     /locus_tag="ACG84Z_000951"
     CDS             complement(50587..52293)
                     /gene="efbA"
                     /locus_tag="ACG84Z_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFP9161810.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        17147 a         9139 c        11268 g        14894 t
ORIGIN      
        1 gaacgagtct tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag
       61 atgaacaagg atctcaaaca gttgctgatc ctcaagcgtt tatcgatcaa atcggctggt
      121 ctgcgtcaga agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt
      181 tgttggaaag tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg
      241 gtgtgaaagg aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaacgg
      301 acaatgggta acgatgaatg aaccattccg aaaatattct tcttattggg aatccttcca
      361 agaccatgcg aatgttcttc gttcaaccag tttttccacg ggcgattatc attatgctgg
      421 cgtgtggaaa agcaatacaa caagttttta tgatgcaaca gcgtacttga caggtcgtta
      481 tgctaccgat ccaaattatg gggccaaatt gaactcattg attaatactt ataatttaac
      541 ccgttttgat acgccatcaa caggttcggc taccacaagt acaacaacaa cgactactac
      601 gacgacttca acgtcatcat cttcaacaac agatgtaaat acaaataatg gtcagacata
      661 tacagtcgtg tcaggtgata cgctatggga tattgcacaa aaatttggca tgtctgttga
      721 tgatctaatg gcgaaaaatg gcatgtctat gtccagttat tctttattag ttggtcaaga
      781 actaaacgtt tgatttagat aaaaaggcaa agaaactacc atatatggta tatctttgtc
      841 ttttttttgc tagtcaaaga cgaatcactc gccataaatg aacagattgt attatgataa
      901 gtaagaagag caaagacaag gaggaattga agatgacagc tatctataac tcagtcaccg
      961 aattgattgg caaaacgcca atcgtcaaat taaataaaat cgtaccagaa gattcagcag
     1021 atgtttttgt aaagcttgag ttttttaatc caggaggaag tgtaaaagat cgtattgctt
     1081 taagtatgat agaaaaagca gaacacgatg gtctactgaa accaggtgat actatcattg
     1141 aacctacttc tggaaataca ggaatcggat tgtcgatggt aggagttgca aaaggatata
     1201 aagtaatcat cgtgatgcct gagacgatga gtatcgaaag acgtttattg atgaaagggt
     1261 acggcgcaga gttgattttg actcctggtg cggatggtat ttctggatca atcagagaag
     1321 cagaacgttt ggcaaaagaa aacggctact ttttaccatt acaatttgaa aatgaagcaa
     1381 atcctcttgt gcatgagaag acgactggtc ctgagataca tcaagcattt ggagtaaatg
     1441 gcttggacgc gtttgttgca ggtatcggta caggaggaac gatcactggc gctggccgag
     1501 aattaaaacg tgtgtatccg aaaatcgaat taatcggggt agaaccagca gaatctgcta
     1561 ttttagaagg gaaagaagcg ggacctcaca aaatccaagg aatcggtaca ggttttgttc
     1621 ctaaaacact ggatacttct gtgtatgata aagtcctttc tattagtgga gacgaagcga
     1681 tggaaacagc tagagaagtt gggcgaaaag aagggatttt agtaggcatc tcatctggcg
     1741 ctgcaattgc tgccgcgcta aaagtcgcaa aagaattagg aaaaggcaag aaggtattag
     1801 ctgtggttcc cgacaatggt gaacgttatt tatctacagc cctttaccaa gagatataag
     1861 gcacttggtt tttctccaga taggtttatg taaaaaactt ttaaagatga aaagaacaca
     1921 caaaaattta tgatgagaaa aattatttga atagagacgt aaaatagtga acgcgactgt
     1981 tttacgtctt ttttcattaa aatacaataa aattgaattt tcttttcatg ttaagtggat
     2041 tttaaaatgt aaaaatagta tgataagacg agaataacaa cgtggggtgt ttacatggaa
     2101 aataagttag tcgaagaggt tatcgaaaag ttaaaaaaag agaacattcg aatcacacct
     2161 caacggtacg cggttttaga atatttgatt gaacatcatt cccatccaac ggctgatgag
     2221 atttataaag cacttgaaca tcggtttcca aatatgagtg ttgcgactgt ttacaataac
     2281 cttcgcttat ttacttcgat tggatttgtt caagaaatga agtacggcga tgcttctagc
     2341 cgatttgatt tcagttcaaa gcgtcattat catgtaattt gtgaaaactg cggtaagatt
     2401 gttgattttc attacccagg gcttgaagat atagaaatgg ctgcgagcag actgactgat
     2461 tttgagatta atgaacatcg gttggaattg tatggactct gtccggattg taaagagtca
     2521 gcaaaaaagg cgcaaatgta aaaacagttt ctataagtgt tatacctaaa aaaagctagc
     2581 tgtgtaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatatca
     2641 aagtgaatat tatcacaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2701 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2761 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     2821 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     2881 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     2941 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3001 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3061 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3121 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3181 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3241 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3301 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3361 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3421 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3481 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3541 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3601 caaagtgaat gaatacatgc agacaagtga tccagacatt tttgcagctg gagactctgc
     3661 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3721 tcgtcaaggt ttacttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3781 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     3841 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     3901 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     3961 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4021 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4081 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagaagcgct
     4141 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4201 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4261 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4321 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4381 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4441 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4501 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4561 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4621 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4681 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4741 aacccctttt tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg
     4801 aataggaaac aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga
     4861 caactgctaa tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca
     4921 gaaatggaaa aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc
     4981 gggaaaatcc ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga
     5041 gccatcagta agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc
     5101 gaagagaata aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat
     5161 agacacgagc aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg
     5221 tcaaaagaag aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga
     5281 agtagcaaat gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa
     5341 aatccgaata ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg
     5401 ccgatgacgc gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg
     5461 ttatctgaga cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg
     5521 aaaccataac agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat
     5581 gtgatgaata gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct
     5641 gaaaattttt tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca
     5701 atcaaagaga agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat
     5761 tgagaaaaga tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat
     5821 aaaggaataa cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg
     5881 gagaaactta aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag
     5941 ccataaacgg catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc
     6001 aactcagcta atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca
     6061 cccatccatc caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca
     6121 tataaggtgg agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc
     6181 catatcgaat ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata
     6241 ataaggatcg gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag
     6301 aaggcagcta gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg
     6361 gagtgagaat aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat
     6421 ccagtgaata agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac
     6481 atgtaaaaac tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt
     6541 ttgtttcctt gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa
     6601 agtgaagata cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc
     6661 tgaccgatca gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac
     6721 gtatactgtg attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg
     6781 gacaaacagt catatctaat cttttactta aaaattatca taggatcggt ctacaatctg
     6841 aagaattttt atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg
     6901 atttgcagat gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg
     6961 atcgtctcgt aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag
     7021 cagatcgata taatctttac cccatctatg atctattagg tgagtattta aaaacacaag
     7081 aaaaaaaata cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg
     7141 aacaagaatt tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag
     7201 aagaagacca ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc
     7261 aggcttatag ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac
     7321 gtacaaaaca acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag
     7381 aagtagaaca gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg
     7441 aggagtagcg gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg
     7501 gaatgtttcc cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg
     7561 cagtgatctt aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt
     7621 ttgcctcttt tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta
     7681 aaataaaaac gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc
     7741 agctgattga acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc
     7801 ctggtgtagg cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa
     7861 tcgcagtaga tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg
     7921 ctacggtcat ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa
     7981 agacacatca tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt
     8041 gcgaggtatg tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag
     8101 aaaaggcgct aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg
     8161 tatgaattat cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa
     8221 gtaaatgtac atactcagta gctaggatgg taacttatta caatttattg cgataaaaat
     8281 aaaagttgtt atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac
     8341 ctataaaata agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag
     8401 gtgtaataaa aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa
     8461 tggatttggg cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata
     8521 aaaaagtgag aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc
     8581 ttaaaagtac agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta
     8641 ataataaaca aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata
     8701 aaaaaagatg gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga
     8761 agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa
     8821 tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta
     8881 taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt
     8941 taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat
     9001 acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc
     9061 acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga
     9121 tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg
     9181 aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga
     9241 agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc
     9301 gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt
     9361 ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt
     9421 atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca
     9481 gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc
     9541 tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga
     9601 aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat
     9661 accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata
     9721 taacccagcg atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc
     9781 tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc
     9841 ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc
     9901 attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc
     9961 atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat
    10021 cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac
    10081 tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg
    10141 attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat
    10201 agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt
    10261 catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc
    10321 ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag
    10381 ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat
    10441 atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt
    10501 gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc
    10561 gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac
    10621 attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa
    10681 aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg
    10741 ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt
    10801 accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt
    10861 atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat
    10921 ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga
    10981 aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt
    11041 agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg
    11101 atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt
    11161 ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga
    11221 agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca
    11281 gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat
    11341 cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt
    11401 cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc
    11461 atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt
    11521 ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca
    11581 aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat
    11641 gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga
    11701 ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa
    11761 agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat
    11821 agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag
    11881 cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa
    11941 ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca
    12001 tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag
    12061 aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc
    12121 ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc
    12181 aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga
    12241 tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga
    12301 agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat
    12361 agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc
    12421 tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt
    12481 agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa
    12541 tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt
    12601 ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta
    12661 cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg
    12721 tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg
    12781 aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa
    12841 gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat
    12901 atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat
    12961 cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg
    13021 caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg
    13081 tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa
    13141 ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa
    13201 aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct
    13261 gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt
    13321 gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg
    13381 cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc
    13441 atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt
    13501 ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt
    13561 tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc
    13621 agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc
    13681 tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt
    13741 tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa
    13801 ataaggagat tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc
    13861 gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag
    13921 aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta
    13981 cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa
    14041 ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt
    14101 cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc
    14161 acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca
    14221 ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg
    14281 gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt
    14341 ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa
    14401 gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta
    14461 ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg
    14521 ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat
    14581 attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc
    14641 aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac
    14701 ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta
    14761 ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta
    14821 aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa
    14881 aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat
    14941 tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat
    15001 tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa
    15061 gaaatcaatc ttctacaaaa agctttagga atcctcgatt gggatacaca aacaggtatg
    15121 cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt
    15181 tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa
    15241 gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa
    15301 catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga
    15361 caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa
    15421 aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat
    15481 gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt
    15541 gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa
    15601 cctgaaacag actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg
    15661 aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac
    15721 ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca
    15781 gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa
    15841 gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat
    15901 gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag
    15961 caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa
    16021 ttttatcgtt tattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg
    16081 acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg
    16141 gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata
    16201 cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt
    16261 ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg
    16321 cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac
    16381 tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg
    16441 gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat
    16501 tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat
    16561 ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag
    16621 tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc
    16681 ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc
    16741 gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa
    16801 atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg
    16861 aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg
    16921 aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat
    16981 taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt
    17041 ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga
    17101 cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt
    17161 acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt
    17221 ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca
    17281 aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg
    17341 taaaagttac ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga
    17401 gtcacaagga acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga
    17461 ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg
    17521 tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa
    17581 ttaaaaattg ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata
    17641 aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt
    17701 gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat
    17761 actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt
    17821 ctcataatca gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca
    17881 cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc
    17941 caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata
    18001 caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa
    18061 gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa
    18121 agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa
    18181 tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga
    18241 agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat
    18301 gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg
    18361 ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa
    18421 aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg
    18481 tgttttctcc atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa
    18541 atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc
    18601 aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc
    18661 gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt
    18721 gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc
    18781 tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga
    18841 aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga
    18901 aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa
    18961 gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac
    19021 aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt
    19081 agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc
    19141 gtctatttaa aattagagaa catgttcacg catatattgt taatcatctg aagatagtag
    19201 taaaaaagat cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa
    19261 attggttcag agttgatcac acggctacgt caagaactag gcagtgaaaa tgtcattgcg
    19321 acagatatac gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta
    19381 atggattacg aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat
    19441 ttggctgctc ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac
    19501 gtgactgggc tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg
    19561 ccaagttcaa tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact
    19621 cttcagcgtc ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat
    19681 tattattatg tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct
    19741 tatgcaacct tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca
    19801 atcaaagaag gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat
    19861 atgccagatg cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt
    19921 catcgaaatg ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct
    19981 attcaaaaaa tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca
    20041 atagcagaat cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt
    20101 tcgccgaaat acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa
    20161 ttggtagaga cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt
    20221 ggctatggta tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag
    20281 taaaaataga aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta
    20341 tgggcacagt gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag
    20401 gatccgccag tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag
    20461 gactaacagg agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata
    20521 tcgaacggat ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt
    20581 attttccagc aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat
    20641 ttggtctttc ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt
    20701 tgatcaattt tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca
    20761 agcttattcc tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact
    20821 tccaactgtt tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg
    20881 gcttgctagc aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag
    20941 aattgaaaaa gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca
    21001 tgatcgttta tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg
    21061 caggaaacag caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa
    21121 gactggtcac agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta
    21181 ctggaatgcg tctcccttat gttatggcaa aagaaaacaa cctgcctttt agcaagctct
    21241 ttgctaaact tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca
    21301 tcgctattgg catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg
    21361 tcatttggat tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac
    21421 ctgatttgtt tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca
    21481 ttggagggac ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg
    21541 ggatagtatt gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa
    21601 aacattcgaa ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga
    21661 ggagtacgtg gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt
    21721 gtctacgatg aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt
    21781 actttgattt gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca
    21841 agcaaccaga aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag
    21901 acaaagcatg tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat
    21961 tgaagactag catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag
    22021 ttctttttct tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa
    22081 aaacaaagta catattcagc atctcgacac cccctttgtg tttatcttac tttactttga
    22141 aagaaatgag aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa
    22201 gagagataca aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt
    22261 gcgctgattg tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa
    22321 tatcgaaagt atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt
    22381 tatttattgt gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc
    22441 caaatgacag ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac
    22501 aacacggtat tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta
    22561 tttttggaac cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat
    22621 tatttccggc tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt
    22681 gaattgacgc agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat
    22741 gtgaatgatt tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta
    22801 tttacattta tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag
    22861 actgtctcat tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt
    22921 attaatttgg tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct
    22981 catatctggt ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc
    23041 aatggatgga cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa
    23101 cgaatttctt taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt
    23161 ttaagctggt tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg
    23221 cagatgagtg cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta
    23281 aatatcttgc tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac
    23341 acatatactg ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc
    23401 aaaaacgctt tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca
    23461 cgaatgaata attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca
    23521 aagggcttca aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga
    23581 aaaaatatca ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct
    23641 ttgtttgaaa aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt
    23701 agggaactag ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg
    23761 gagatccgtg tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg
    23821 catcaccaac agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat
    23881 gaacaagcgc tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca
    23941 ttggatatgg gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg
    24001 cagtttttag ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac
    24061 atggaaaatc caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa
    24121 aattggctga tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca
    24181 attggtcatc cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt
    24241 gccgattact tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca
    24301 agagagagaa aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg
    24361 actgatttag ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa
    24421 attccagaag atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta
    24481 aaaggaacgg ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa
    24541 aaattgggcg tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac
    24601 gatcgtaata gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt
    24661 ggtcttgtga agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg
    24721 gcaattgcag aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact
    24781 gctcgtaaaa ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt
    24841 gtcacaatct cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct
    24901 tcaataaaag gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc
    24961 atttcagcta ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct
    25021 tcaagcaact gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc
    25081 ggcttgaagc aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga
    25141 tcaagaaata gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca
    25201 ggaatccctt gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc
    25261 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    25321 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    25381 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaatt aagtacgaaa
    25441 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    25501 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    25561 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    25621 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    25681 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaaggac
    25741 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    25801 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    25861 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    25921 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    25981 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    26041 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    26101 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    26161 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    26221 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    26281 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    26341 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    26401 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    26461 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    26521 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    26581 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    26641 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    26701 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    26761 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    26821 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    26881 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    26941 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    27001 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    27061 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    27121 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    27181 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg
    27241 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    27301 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    27361 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    27421 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    27481 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    27541 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    27601 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    27661 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    27721 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    27781 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    27841 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    27901 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    27961 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    28021 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    28081 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    28141 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    28201 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    28261 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    28321 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    28381 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    28441 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    28501 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    28561 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta
    28621 ggattcatta gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc
    28681 ccaaaagatg gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat
    28741 gccatgccaa caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt
    28801 cccagagtac ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat
    28861 aaatcaataa cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc
    28921 ttagtgttag gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta
    28981 gactctgctc ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa
    29041 gcaataggtg cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg
    29101 ttgaaaccag aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag
    29161 gaagagagga gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact
    29221 agaaggggta aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca
    29281 gcggacaaaa aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt
    29341 tgtctctaag ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt
    29401 gaacagtcta tcagatactg cttcatccat attgactttg atcggattta aaattgctgc
    29461 aaagccagca gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt
    29521 atttgtttcg atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa
    29581 aatcatccat ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc
    29641 catctttttg aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc
    29701 tgaaacattg agagctacag caacagatag ttataatgat gtctttacta cactggctgt
    29761 attgctttca gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt
    29821 tgctttagca ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga
    29881 actattagga agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc
    29941 ttgcgatgat atacttggct atcatgattt attggtgcat aactatggac ccaataaacg
    30001 ctttgcatca gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat
    30061 tattgatctg atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt
    30121 ggatccaatg cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat
    30181 tcttcttgaa acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa
    30241 aacgctgcaa tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga
    30301 aagaatctta cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt
    30361 tgatcacaat tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta
    30421 atttaaagag tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct
    30481 gctcctttat ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga
    30541 agttcttgga ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg
    30601 accgtagaaa ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg
    30661 tttttcttta gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc
    30721 cctatagaaa gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca
    30781 cctccactag gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa
    30841 agagattctc ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg
    30901 tgagaggtta gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca
    30961 tctattggtc attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca
    31021 caggtcctta ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag
    31081 gtttgcggcg ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt
    31141 ggaaagaccg agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg
    31201 tgcaaatgat gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc
    31261 aagtagtcct ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc
    31321 cttatacgaa aaaaagaaaa agctaatttt aaaaatcaga acctaaaaaa acgaattttt
    31381 acaggaaaag aaaagagtga gacgtacggt tcatcccgtt tagcgtctca ctctatttgt
    31441 ttatctattc atgcatacta gtatcggtag tctgaacgtt gcctttcttg acatgggcag
    31501 cttgtgttcc tcgattccct tcgatgatct caaattcgac cacttgattt tcttccaaag
    31561 ttttgaatcc ctcttcttca atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat
    31621 aactgataaa gccgtatcct tttttgttgt caaaccattt tacaattcct gtggtcaaag
    31681 cactcacgac ctttctaaag tctgatcata gccttcatta taaagagtat ttataagtac
    31741 gtcaaataaa ttaaaaacct gtaattttat gttttttttc tgaataaaaa aaggtataat
    31801 tggcatatct taacaaagaa gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa
    31861 atgaagaatg atctgcaaat ttcacaagaa acagagctag aaccgattgt tgaagtggct
    31921 agtaaattag atcttaagga agacgatttg gaactgtatg ggaaatataa ggcgaaaatc
    31981 aatttttctg gaatcaatcg atcaaaggat aacgctgagg ggcatttgat cttagttact
    32041 tccatcaatc caacaccagc tggcgaagga aagtcaacga tcactgtagg gttaggagac
    32101 gcgctcaata aaatcaataa aaaatctgtt attgcattgc gagaaccctc acttggtcct
    32161 gtgatgggaa tcaaaggtgg tgctgcaggc ggaggatatg cacaggtatt gcctatggaa
    32221 gatatcaact tgcattttac tggtgacatg catgctatca caacagctaa taatgcatta
    32281 tctgctcttt tagataatca tattcatcaa ggaaatgaat tgaacatcga tgcccgccga
    32341 gtgatttgga aacgggtagt cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc
    32401 ttgggtgggc caatccaagg tgttccaaga gaagatgggt ttgatatcac agttgccagc
    32461 gaaatcatgg ctatcttgtg tcttgcggca gaccttgaag atttaaaggc tcgtcttgca
    32521 aggatcgttg tcggctatac atttgaccgt cagcctgtga ctgctggaga cttgaaagca
    32581 gaaggcgctc tggcattact gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt
    32641 tacggaacac cagcttttgt ccacggggga ccgtttgcca atatcgctca tggctgcaat
    32701 agtattttag ctaccaagac agcattgaga ttagcagatt acgttgtcac agaggcagga
    32761 tttggtgcag atcttggcgg agagaaattt ttagatatca aagtacctaa cttgaaaaaa
    32821 gcgccggatg ctgtggtgat tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg
    32881 aaaaaagatg aacttaaaaa tgagaatctt gatgctttga aagtaggttt tgcaaattta
    32941 aagcgccata tacgtaatat ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa
    33001 ttcgtaacag atacagacaa tgaactcaca ctgttggagc acttgtgtga aaatcagggg
    33061 attcttgcca agagagcgag tgtatgggca gatggagcag aaggcggcgt tgatttagca
    33121 aaagctgtag tacgattgat tgatagaaaa gaagctaatt acaagccatt ataccgccta
    33181 gaagaaacga tacaagaaaa gacagaaaca atcgtcaaga aaatttacgg aggaaatggt
    33241 gttgttttca gcaaaaaagc gcaaaaacaa atagaagagt ttacgaagaa tggatgggac
    33301 aaactgccga tttgtatggc aaaaacacag tattcatttt ctgatgatcc ttcactgcta
    33361 ggtgcaccgg aagatttcac catcacgatc cgcgaaatca tcccaaaatt aggggcagga
    33421 tttttagtag ccttgactgg agatgttatg acgatgcctg gtttgcctaa aaaacctgct
    33481 gcattgaata tggacgtgac aaatgacgga gaagtgttgg gattgtttta agcttgatta
    33541 taatctacca tcgaaggagc tgtattttga ctacagcttc tttttttaga cgatagggaa
    33601 ttaattttgt ttacactagg atcattcttt ttctttattg tattttgagc tatactaaag
    33661 cataatagga gggtatgatg aaaacgacat ttataagaaa aaccggtttt tacggtatgg
    33721 gtagctcgat tcagctaaga atcaacaatg aaaaacgcag tgttctcagt catgaacaaa
    33781 agataacgct tgatctggaa gtgcccttta cgatgcaggt caccttttat tggctaaaaa
    33841 gccccgttta tacagtgaaa gaagcaaagc ctgcttatgt gatcacaatg aattacttga
    33901 ttcttcaaat ctatccgttt ttatttctag caactgggtt gggggccgtt ttcctacaaa
    33961 atttattttt cagttttttt gcagttattg tgttgattgc gttctttttc tatataaaaa
    34021 accgggcata tttgatcaag gaggaaaatt atggcaaact ctgatctttt tttaatcagt
    34081 ttcaatcgaa tcgaaaaatg gatgagagac gagatgggaa atgcacgaaa tatgggattt
    34141 accgaacttg tcagacgcct agctcaaaga aaacaattaa tgatcagaaa atacgaagat
    34201 gatcttttac agcttgctca gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat
    34261 tttgtcattg cagagccaaa tgattggaca gtcaagcgaa tccagctgat cgaacaagaa
    34321 ctgattcagc ctgaaaccgt gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa
    34381 gatcttccgt tacttgaact gttaaagata gtagcagaaa aaaggtattc acaatttccg
    34441 ttatacaata aaggaaaatt tgtagcattg attactttac gtaatatcgg gttttggcta
    34501 gcaaaagaaa gccaaaaagg tccggttgat ttaacaaata aacgagcgtt ggatttgatc
    34561 atccaaaacg gaaagtacac aaattatcat tttgttccag ctaaaacaca tatttacgag
    34621 gttgaagcga tgtttcgtga gcaagggact ttggaagccg tacttatcac taaagatggg
    34681 aatcccgatg gtaatctgct cgggatcgta cgacctcgtg atatttataa acaaatagaa
    34741 aaggattgat tttttgttaa ttatttattg gatattcagc gctttgctag taggagtgga
    34801 tcagttggtc aaatggtgga tcactgataa tctagcgctt ggagagacga aaaatcttat
    34861 accaggtatt ttgtcactga atcatattcg aaacactgga gccgcatgga gtatgctaga
    34921 agggaagatg tggttcttta ctatagtgac actcattgca gtcgttgtga ttctcacatt
    34981 gatgattaaa aatcgtgaaa aaggtaatcg ctggttcatg attggattga gtttgattct
    35041 agctggtgcg attggcaatt ttatcgaccg tattcgtctt ggctatgtag tagatatgtt
    35101 ccagacagat tttatgagct ttccgatttt taacgtagca gatgtgacac ttgtatgtgg
    35161 agtgatttgt atgttaattt atattatttt agatgaaaag gatcaaagaa aaaaatgaca
    35221 gaacttaaaa cgacgattca ccatgaatct ggtaggatcg ataaagtatt gactaattta
    35281 ttcaccgatt acagtcgttc gcaaattcag ctgtggctga aaaatggagc ggtttctgtc
    35341 aatggacagc cagtcaaagc aaattacaaa gtaaaacaag gagacgagat tactgtcttg
    35401 atccccgaac cagaaacatt agatgtggtc ccagaaaata tcccgttgac gatcgtttac
    35461 gaagatgaag atgtagcggt gataaacaaa cctcaaggaa tggtcgttca tccttcagca
    35521 ggtcatacgc atggcacaat ggtcaatgcg ctgatgtacc atatcaagga tctttctacg
    35581 atcaacggcg ttattcgtcc aggtattgtt caccgaatcg acaaagatac ttccggactg
    35641 ctaatggttg ccaaaaatga ccaggcacac gaatcattag ctcagcaatt aaaagataag
    35701 acctctttgc gcaaatatgt tgctttagtc catggagaga ttcctcacga aaaaggaacc
    35761 atcaatgcgc caatcggccg ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat
    35821 gggaagtcgg ctgtcacaca ttttactgta ttggaacgtt tcgaaggatt tactctggtt
    35881 gaattaaaac tagaaaccgg aagaacacac cagatccgtg tgcatatgaa gtatatcggt
    35941 tatccgttag ctggagatcc agtatacgga ccgaagaaaa ctttgaaagg caatggtcag
    36001 tttctccatg cgcaaatgtt aggttttacg cacccgacta caaacgaaaa gatgatcttt
    36061 gaagcacctc ttccagaagt ttttgaaaaa actttagaaa aattaagaaa aaacattgca
    36121 ttttaattta gataacggta tagtaattaa caacgaaagc ataaaactta atagaattcc
    36181 tttaagttta gtcccgtgag gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat
    36241 aagtagattg ctcattgaca tagtatagct atcagtgtat cagtatacgc tcagtctaaa
    36301 cattcctcct gtcctcttag ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa
    36361 atgcaagcaa aagaagtagt agatcaggta accatgaagc gagcattgac tcgaattact
    36421 tatgagatta tcgagagaaa ccatagtatc caagatatcg tattggtagg tatcaaaaca
    36481 cgaggaatct acattgcatc aagaattgcc gaacgcctga agcagctaga agatatcgat
    36541 attcctgtag gagaactgga tatcacttta taccgagatg acaaaaaaga aaatccagaa
    36601 gaaccggaac ttcattcttc tgacatccca gtttccttag aaggaaaaga agttattttg
    36661 attgatgatg ttttgtatac aggacgaacg attcgagcag caatggacgc agtaatggat
    36721 tttggcagac caagaaaaat ttcattagca gtcctggtcg atcgtgggca tcgagaattg
    36781 ccaatccgtg cagattatgt tgggaagaac attccaacat ctcgggcgga agagatttta
    36841 gtagagatgc aagagcttga tggacaagat cgcatcatga ttttgaaaga ggaagattag
    36901 aggagagaga aacatgtcgg agaaaaaagg atttcataat gatgacgtgg tgttagatat
    36961 ccacgatcgc ccaaccccag gacattgggt aggattaagt ttacaacact tgttcacgat
    37021 gttcggagca accgtgttag tccccatctt agtaggtatc gatccaggta ttgcgctagt
    37081 cagttcagga ctaggtacat tggtgtactt atttactact aaaggaaaga tacctgcgta
    37141 cttaggaagc agcttcgctt tcattgcagc gatgcagctt ttgatgaaaa cagatggtta
    37201 tccagcgatt gcacaaggag cagtcacaac tggattagtc tatttgattg ttgcgctgat
    37261 catcaaaaag atcggttcag catggctgga taaaatcttg cctccaatcg tcgtcggtcc
    37321 agtcatcatg gttatcgggt tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa
    37381 tcagggcacg tatgatttca agtatattgc tgtagcgctg atcacattag gattaacaat
    37441 tttcttcaac atgtggctaa gaggttttct cggattgatt ccgattttac taggtattat
    37501 tagcggatac atcgtagcct tgctgtttgg aatcgtggat actaagccaa tcgtagacgc
    37561 tgcctggttt gctgttccta actttgagat tccctttgta caatatgaac caaagctata
    37621 tcttggagca atcacaacaa tggcacccat cgcttttgtg acgatgacag agcatatcgg
    37681 ccatcttatg gtattgaata aactaactaa acgtaatttc tttgaagaac cgggtcttca
    37741 taagacgttg acaggtgatg gattagcaca aatcgtggca gcctttgtcg gaggtcctcc
    37801 tgtaacaagt tacggtgaaa acattggtgt tctggctatc acacgtgtcc atagcgtgtt
    37861 tgtgatcggt ggagctgcag tatttgcagt cattttagga ttcgtaggaa aattaagcgc
    37921 tttgatttta agtatccctg gaccagtcat ctcaggaatc agttttatct tatttggagt
    37981 aattgccgca agtggaatga agattttaat cgagaacaaa atcgattttg ataaaaagaa
    38041 aaatctgttg attgcttcag ttatcttagt agtaggaatt ggcggactcg tctttgaagt
    38101 aggcacattt acattgtcgg caatggcatt agcaactgta cttggcatca ttttaaatct
    38161 tatcttacca gaaacttcac gaagcgaaga aaactaagga ggaaacatta tgatcatcaa
    38221 atcagaacgt atcagcttaa agcatttatt gaccgttgag gcacttactg atcaagaagt
    38281 tatgggcttg atccgcagag ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa
    38341 gcgccagtac tttgctacaa acctcttttt cgaaaatagt actcgcacac ataaaagctt
    38401 cgatgtagcg gagaaaaaac tagggctaga agtgattgaa tttgaagcaa gcacaagctc
    38461 tgtccaaaaa ggggaaacac tatacgatac agtactgacg atgtcagcat taggcgtaga
    38521 cgtagcggtt atccgtcatg gtgatgagaa ctattatgac gaactgatac aaagtaaaac
    38581 aatccagtgt tcgattatca atggaggaga cggaagcgga cagcatccaa cccaatgctt
    38641 gcttgatttg atgaccattt atgaagaatt tggtcatttt gaaggtctga aagttgccat
    38701 cgtaggtgat atcactcact ctcgcgtagc taaatccaat atgcagatgt taaaacgtct
    38761 aggcgcacaa gtattcttct caggtcctag agaatggtac gacgatgaat tcgaagtgta
    38821 cggacattat atgccattgg atgaactact agatcaagtt gatgtcatga tgatgcttcg
    38881 ggtgcaacac gaacgccatg atggaaaaga aagtttctca aaagaaggct accatcagga
    38941 acatgggtta acagttgagc gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc
    39001 agcaccagtt aaccgtgatg tagaattagc tgattcatta gtggaaggat tacagtcgcg
    39061 gatcgttcag caaatgagca atggagtatt cgtcagaatg gcaatcttag aagcagtgct
    39121 aaatggaaaa gcgtaattat aggaggatga aaaaatgaaa acactcatta aaaacggtca
    39181 gatcaataca cgaaaaaata tgacgacacc agcagaaatt tggatagaag atgggcgaat
    39241 caaagcaatc ggtacaggat tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg
    39301 acaattgatc acacctggtt tagtggacgt ccatgttcat ttgagagagc caggatttac
    39361 atacaaggag acgatcgaag ctgggactcg ctcagctgct cgtggcggtt tcactactgt
    39421 atgcgcgatg ccgaatttaa atcctgtacc tgatacggca gaaaagctga gacaagtata
    39481 tgacatcatt agaaaagatg cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa
    39541 tctgcgaagt gagaaattag ttgatcaaga agcactgatt gaagaaggtg cttttgcttt
    39601 cacaaatgac ggtgtaggtg tccaaacagc tgggacgatg tatctggcta tgaaagaagc
    39661 tgcaaaaaac aataaagccc tagtagccca tacagaagat gaatctttat tatttggcgg
    39721 cgttatgcac gctggcaaga aggcagaaga acttggtctt cccgggatct taagcgtaac
    39781 cgagtcttct caaattgcta gagatctgtt gctagctgaa gcaactggtg ttcattacca
    39841 tgtttgccat gtttctacta aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg
    39901 aatccacgta acagcagaag tttcacccca tcatcttatt ttgatcgacg aagatattcc
    39961 cgaagatttc ggcttttgga aaatgaaccc gccgctaaga ggacgggagg acagagaagc
    40021 tttgatcgaa ggcttgcttg acggtacgat cgattgcatc gctacagacc atgcccccca
    40081 tggattagaa gaaaaaagcc aaagtttcat gaaatcacca tttggtatcg taggaagcga
    40141 aacagcgttt caactgatct atactcattt tgtagaaact ggtcgattca cgttggaaca
    40201 agtgatcaat tggttggcag ttaaaccggc tgagattttt ggtttgaatg caggaacgct
    40261 aacggttggt gcccccgctg atgtagcagt ttttgatatt acacaaactt gcacgatcga
    40321 taaagaagac tttttatcaa aaggggagaa tacacctttt atcggctgga aagtaaaagg
    40381 cgaaacacaa atgacttttg tcaacggaaa acttgtgtgg cagaagggag aataaaagta
    40441 tggaacgttt gcttatatta gaagatggaa cagttttcga aggaaaggct tttggtgcag
    40501 atgctagtgt cttcggagaa atcgttttta caacaagtat gactggttat caagaaacta
    40561 tcactgatca aagttttaac ggtcaaatca ttacatttac ctatcctatg gtgggtaatt
    40621 atggggtaaa tagagatgat tatgaatcga tttctccaac atgcaaagga gtagtagtaa
    40681 aagaacatgc acgtgtagct tcaaactggc gaaaccaaat gacgctagat tcatttttga
    40741 aacaaaaagg aattcctgga atatcaggta tcgatacgcg cgcccttact cgcaaaatcc
    40801 gtgaagtcgg aacgatgaaa gctagtatag ttgatgctgg agattccttc gaacatgcat
    40861 ttgatcagct gaaagcaacc gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca
    40921 aaccttatcc aagtccagga acaggtcgga aagtcattgt cattgacttc ggcttgaaac
    40981 atagtatttt acgagaattg agtaaaagaa actgtaacct cacagtactt ccctataaca
    41041 cagatgccga gacgatttta gcgctatcac cagacggagt catgctgacg aatggacctg
    41101 gtgatccaaa agatgtgcca gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac
    41161 cgatttttgg tatttgtctc ggtcaccagt tatttgcttt agccaacggt gcagatacct
    41221 ataaaatgaa attcggacat cgaggattaa atcacccggt acgagaagta gcgaccggaa
    41281 gaattgattt tacttctcaa aatcatggct atgcagtcga tgaagccacg attgatccag
    41341 aaaaactcat cgtaactcat gtagaagtaa atgacggaac agtagaagga gtcaaacaca
    41401 gagattatcc cgctttcagt gtgcagtttc atccagatgc tgcccctggt ccgcatgatg
    41461 cactacattt atttgatgaa tttatggaaa tgatggacgc aggaaaggag cagtaaacag
    41521 atgccgaaac gtacagatat caagaaaatt atggtgattg gatctggtcc gatcatcatt
    41581 ggtcaagccg cagaatttga ctacgcagga acacaagcct gccttgcctt aaaagaagaa
    41641 ggatatgaag tggttttagt aaattctaat cctgcgacga tcatgacgga taaagaagtg
    41701 gcagatcaag tatatatcga accgatcaca cttgaatttg tatcaaggat tcttcgaaaa
    41761 gagcgtccag atgctctcct tccaacttta ggcggacaga caggcctcaa tatggcaatg
    41821 gagctggcag catcaggtat tttagaagaa ttgaacatag aacttctagg aacaaagctt
    41881 tctgcgatcg atcaagcaga agatcgtgat ctattcaaac agttgatgaa agaattgaat
    41941 cagccaatcc ccgagtctga aatcgtcaat acagtagaag aagctgtaga ttttgcaaat
    42001 aaaatcggct atcctgtcat cgttcgtcca gcctttactt taggcggaac tggtggaggt
    42061 atgtgtgaaa atgaagaaga attacgtatc gtatcagaaa atggattaag tctttccccc
    42121 gctacccaat gtttgattga acgaagtatt gcaggtttta aagaaattga atatgaagtg
    42181 atgagagatt cggctgataa tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg
    42241 ggtatccata caggtgattc tatcgtattt gcccctagtc aaacattgtc tgaccatgaa
    42301 tatcaaatgc ttcgtgatgc ttctctttcg attattcgag cacttaagat cgagggaggc
    42361 tgtaatgtcc aactcgctct tgatccacat agttttaatt attatgtgat tgaagtcaat
    42421 ccgcgtgttt ctcgttcatc tgcgttagca agtaaggcga ctggctatcc gatcgctaag
    42481 ctagctgcta aaatagcgct tggattaaca ttagacgaaa tgaaaaatcc tgttacagga
    42541 acgacttttg cagaatttga acctgcatta gattatgttg tagctaaaat tcctcgctgg
    42601 ccgtttgata agtttgaaaa cggagaacgg cttttaggca cgcagatgaa agcaactggt
    42661 gaagtgatgg ctatcggtcg gaatatcgaa gagtctttat tgaaagctgt gcgttcttta
    42721 gaaatcggta cacaccatat cgaacttcct gagttggcag acatcacgga cgatgaccta
    42781 atccaaaaag tggttcgagc acaagatgat cgcctgtttt atgtagctga agctattaga
    42841 agagggtaca ccatagaaga attagcggat ttgacaaaaa tcgatttatt ctttttagat
    42901 aaactgttgc atatcgtaga aatcgaacag cagttgaaac agcagccgtt ggatgacaag
    42961 atattgaaaa cagcgaaaca aaacggtttt acagacaaaa aagtggcgga gctgtgggaa
    43021 ataaacgaag aagccgttcg ccagatgaga aaagaaaatg atttgattcc tgtatataag
    43081 atggttgaca cttgtgcagc ggaattcgaa tcaaaaacac cttattttta tagttcctat
    43141 gaatatgaaa atgaaagttc acgatcagaa aagccctcaa ttctagtact gggatctggt
    43201 cctatccgta tcggacaagg ggttgaattt gactatgcga ctgtgcattc tgtcaaagca
    43261 atccagcagg caggatacga agcaatcatc atgaacagca atcctgaaac agtttcgact
    43321 gacttttcta tttcggataa attatatttt gagccattga ccttcgaaga tgtgatgaat
    43381 gtgatcgagc tagaacagcc gataggagta atcgttcaat ttggtggtca gacagcaatc
    43441 aacttagccg aacctttgac tgctgctggt gtaaaaatct tagggacaac gatcgaagac
    43501 ttggatcgtg cggaaaatcg tgatttattc gagcaagcgc tgaaagagtt ggatattcct
    43561 caacctttag gggatactgc tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt
    43621 ggttatccag ttcttgttcg tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt
    43681 gaaaaccagc gagatttaga agattacatg gaacatgctg tgaaagcatc tccagaacat
    43741 ccagtactag tggaccgtta cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac
    43801 ggtgaaacag tactcatccc agggatcatg gagcatattg agcgtgctgg tgtccattca
    43861 ggggattcaa tggctgtgta tccacctcaa acattatctg aatcgatcaa gaaaacgatc
    43921 gaagattaca cgatccgctt agcattaggt ttgaattgtg tcgggatgat gaatatccag
    43981 tttgtcatcc atgaaaatga ggtttatgtg atcgaagtca atcctcgagc aagtcggact
    44041 gttccattct taagtaaggt gacaggaatt ccaatggcac aaattgcgac gaaagctatt
    44101 ttgggagaga aactaaagac acttggttat gaaaacggac tttatccaga aacaaaagaa
    44161 gttcatgtta aagcacctgt cttttctttt acgaaattgc agaaagttga tacttactta
    44221 gggcctgaaa tgaaatcgac tggagaagta atgggatctg acagacaatt agacaaagct
    44281 ttgtacaagg cattcgaagc ttctggatta cacttgcctg aatatggagc cgtattattt
    44341 acgattgcgg acgaaacaaa agaagaagca ctagaattag ctaaacgttt tacagaaatt
    44401 ggctatagtc tgataggaac gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc
    44461 gttgaaacag tagcgaaaat ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata
    44521 agagatggta aaacacaagt ggttgtcaat acgattgata aagatcgggg aaatgcttct
    44581 aaagacggtt tcatcatccg aagagaagca gttgaacatg gtattccatt gtttacttct
    44641 ttagacacag cagatgcgat cgttcgagtg atggaatccc gtgctttttc aactaaccct
    44701 atttaacggc gagcacatgt taagacaaaa agacgaaaaa ccgttgcagg aggggacaga
    44761 tgaaacaaga aatgatggaa atcgttcagc aaaaacagct ggcaccaaag atttttgaaa
    44821 tgacattgaa aggtgatcta gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc
    44881 tcgtgccgcg tgcagacttg ctattacgcc gaccgattag cttgaatcat atcgaccacg
    44941 aaacaaatac ttgccgtatc atttatcggg tggaaggtga ggggactaga gtcttctcta
    45001 ctctttctgc cggagaccat ttagatgtca tgggtccttt aggcaatggt tttgatttgt
    45061 ccaatcttca tacaggagac gaagtattta taatcggtgg aggaatcggt gtccctcctc
    45121 tatatgagtt atcaaaacag ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt
    45181 ttgccacaca tgaagtcgtt tattatgaaa aagaatttaa tcgtctagga gaaacaagaa
    45241 tcgctactga cgatggaaca tacggtatgc acggaaatgt cggtaattta ttgttaggaa
    45301 cgaagacgga acctacagct gtttttgcat gtggttcaaa cgggttattg aagacagtgg
    45361 aacagctgtt ttcttcgcat caaaatgtcc agttatcatt agaatcccgc atggcatgtg
    45421 ggataggggc ttgctatgct tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa
    45481 gtgtgaaagt ttgtgacgaa ggaccgattt ttaaaatagg agaggtaatt atatgaatga
    45541 gaatccttta gcggtcaaac ttcctggcct agaattaaaa aatcctatca tgccggcaag
    45601 cggctgtttc ggttttggca aagaatacgg aaaatactat gatttgaatc agcttggatc
    45661 gatcatggtc aaggcaacga ctccaaatgc ccgctttggc aatcccacgc caagagtggc
    45721 ggaaacacca tctggcatgt tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt
    45781 tatgcataaa cttcttccag aattagagga gtacaatgag ttacccatca tcgcaaatgt
    45841 tgctggtgct tgtgaagaag actatgtaga agtttgtagc aaaattggcg aagcaccaaa
    45901 tgtgaaagca atcgagctga acatttcttg cccaaatgtc aaacatggcg gaattgcttt
    45961 tggaacagat tctgatgttg cttttcaatt aacacaagca gtaaagaaag tttcttctgt
    46021 tcctgtctat gtcaaattgt ccccaaatgt aacagacatc gttccaatcg ctcaggcaat
    46081 cgaagctgga ggggcagatg ggtttacgat gatcaatact cttcttggta tgcggattga
    46141 ccttaagaca agaaaaccga ttttagccaa tcaaacaggt ggactctccg gaccagcaat
    46201 caagcctgtc gctattcgtt tgattcacca agtagcaagt atatccagcc ttccaatcat
    46261 tgggatgggc ggcgtgcaga cagtggatga tgttcttgag atgtttatgg ctggagcaag
    46321 tgctgtagct atagggaccg cgaatttcac cgatccgtat atctgtccta aactaattaa
    46381 agagctccct gtgcgaatga gcgaactagg catcgaatcg ctggaaagat taatcaaaga
    46441 agtgagagag gaacgtgaac gatgaatcaa ctagaccaac gaccaattat tgcattagat
    46501 ttttcaacta ggcaagaggt agaagacttt cttcgatttt tcccgaaaga agaaaaattg
    46561 tttgtgaaaa tcggaatgga attgttctac caagaaggac ctgaaatcgt acgttatcta
    46621 aaagaggctg gtcataatgt atttttagat ctgaaacttc acgatattcc gaatacggtc
    46681 gaaaaagcaa tgcggggatt ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct
    46741 ggcggtattc gtatgatgga ggcggcaatg cgaggattag aagaggggac tccagaaggt
    46801 ggaaaacgtc cgctacttct agctatcact cagcttactt ctacaagtga agaagaaatg
    46861 catgccgatc aactaatcga agtttcttta gaaaaaagtg tgatccatta tgctagctgt
    46921 gccaaaaaag caggattaga tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa
    46981 gaaatggcag gagacgaatt tgtttgctta actccgggta taagaccaga aggaacagtc
    47041 gcaggagatc agacaagagt agtcacacct tctcaggcaa aaaagatcgg ctcaactttt
    47101 atcgttatag gtcgaccaat cactcagtca actaatcctt ataaagcata tcaaacgatt
    47161 caaacagaat ggagctaacc taaaatgaat gttgaacaaa gtatcgcaaa agacttatta
    47221 gaaattgaag cagtattttt aaatccaagt aatcctttta catgggcaag tggaatcaaa
    47281 agcccaattt actgtgataa ccgaatcacg atgagctatc caaaagtccg aaaagagatc
    47341 gcaaaaggat tagcaagcaa aatcaaagaa gcttaccctg aagtacaagt gattgctgga
    47401 actgcaacag caggaatccc tcatgccgca tgggtagcgg aaatactgga tttgccaatg
    47461 gtctatattc gaagtaaggc gaaagatcat gggaaaggta accaaatcga aggacgtata
    47521 tttgaaggtc agaagatggt tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg
    47581 gaagcagctg aagcagcaaa aagagaaggt gcggatatcc ttggtgttgc ggctatcttt
    47641 acgtatgagt tgccaaaagg aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg
    47701 ttgaccaatt attctgtatt gattgaagca gctttagaag atcgttatat cgatgagcaa
    47761 gaattaactc tgctaaaaga atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc
    47821 ttgatgaaga tagagaaatc cgatttgtgt ctccagaatc atcaattgga atagcaaaaa
    47881 tccaaaaact gattgcgaga agcatctttt catcaggtat gaaaagaaac ttctatcgtg
    47941 atcagttttt gattttttta aaattcattt ttctaagact ggttagcaga aagaagagaa
    48001 taatctcttc tcttttttct attatatata gattttctct attttttggt aagggagctg
    48061 tttcaaaaat ggtaaagagc ggaaatgttg cgaatatcag ttatttaatg atatgatatt
    48121 cggaaaaaga aatctcaaag ggaggtaact tttatggggt tgaatgaatt tattttagga
    48181 ttgaacaatt tagagacgat cacaagggca cctggatttt ttaaatatac agagcataca
    48241 gttgcagcac attcgtatcg tgtagcatct attgcgcaag ttctaggaga cattgaagaa
    48301 gcgaatggac aaccgatcga ttggaaactg ctctatgaaa aatcattgaa tcatgactac
    48361 acagagcgtt ttattggtga tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga
    48421 gggatgctgc aaacagttga agaaaagatg acggacgaat tcatcaacca agagattcca
    48481 gctgagttcc aagaagttta tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa
    48541 ggagaactat tagccatttc agataaggtt gaccttcttt atgaatcttt tgatgaaatc
    48601 atcaaaaata acccggaaaa agtttataag gagatgttca ttgaggcagt gactacgatt
    48661 aaaagctttg aacatcggcc ttctgttcag tatttcttta aagagatatt tccggaacta
    48721 ttgaaccagg aattttatgg aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag
    48781 aaagaagaaa aataaaaatg atatgagatg cagggggaag tatagttgaa aaagaatatg
    48841 gatgtcgaat ggggctattc tggagacaaa ggtccggaaa attgggcgag tttatgtgat
    48901 tggtttgcga gaggtgcgga atttccattg cagtcgccta ttcatttgac caagggggaa
    48961 gaaaccaaaa tagaaggaga cacgctttcc tttcattatc aaaagcaacg gtttactgac
    49021 aaggaattca aaaacacgat tcatttagta ccttttgacc aactcagtta tgtagagttc
    49081 aagaaagaac gctattattt gacagatatt catttccact tgccttctga acatatcatc
    49141 aacggaaaac aggaagatat tgaatttcat tttgttcata tgaacagcaa aaaagagaat
    49201 ctagttgtgg gtgtcatgta ccagctaatg gtacaggaag gttggctgta taatcaagaa
    49261 aatggggaaa gttggaactt agaaaaacat gagcattggg taaatccgga tgtgttcttt
    49321 ccggagcaaa aaagccattt ccattatatt ggctcattga caactccgcc taccagcggg
    49381 ccaatccaat ggtttgtaat ggatcatgta ggaaaactga accaagagtt tcttctcccc
    49441 ttcgatggtc agtatgctcg accgaacaac cgaccaatcc agcccttgaa tggaagagaa
    49501 atttattatt tcgaggagtt tgagcaatga atattcagca gatgaaatac gtggtcgctg
    49561 tagcaaacaa tggtagtttc agagaagcgg caaagaaaat gtttgtctcc cagccaagtc
    49621 tttcagctgg tatcaaagaa ttagaaaccg agttagggat cacgctgttt actcgaacga
    49681 atcgaggggc atatttaaca gaagaagggc aagacttctt aaatcgtgcc gagaaaatat
    49741 tggtccagct tgatacatta gaaactcact atctaacgag tgaaaagaga gacaattttt
    49801 cgatcgctgc ccagcattat gatttcttag gtcctttgac cgcacagcta ctcgaggaat
    49861 tcaaagacga gatcaaacaa tttcggatca tggagacgac aacagcgaga gtgatcgaag
    49921 aagtcaaaga gcagcacagt gagatcggca ttatttatat gaatgagcat aatcaagctg
    49981 gtatcagaag atatttacaa caaggagagc taagtggccg cagcattgga aaattcaaaa
    50041 cgcatatttt tttaaggcaa ggacatccat tagctgaaca cgcagagatc accaaagaag
    50101 aattgttatc ttatcctcaa gttcgtttta cacaggatgg aaataatttc ccgtattttt
    50161 atgaagacct tatcgagatc cctgatcaag aaacagtgat ttatacgagt gatcgaggta
    50221 ctttgatgaa tatcgttctt gaaactgatg cttacgcttc aggatctggt attgtgattg
    50281 gagggattcg cgagcacttg cggttaatcc ctttggcaga aggcgaacta aatgaatttt
    50341 atatcattta ttcggcgaaa cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc
    50401 ttactcggtt actggaccag cagagctaag aaaagcagat gagaacgctg tttattgaac
    50461 accgttgatc aaaaaagagg ggttgtgaca gaattttgtc acaactcctc tttttgtagc
    50521 aaacaattta taactaattg ctgttgtggg aaagtacgca aatatgattc tagaaacact
    50581 cattgattac ctgttttgtt tcatagctgt aattttttct tcttctggtg tcacgataat
    50641 cgtcttttgg ttttcataaa taacataacc aggcttggcg ccatttggtt ttcggatatg
    50701 ctttacctgt acaagatcaa ccggcacttg ggcagagtat cggtattttg aaaaataggc
    50761 agctaactcg gcagcttctg taattgtttc atctgagggc ttgtcacttt taatgatgac
    50821 gtgcgaaccg ggtatatttt ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat
    50881 tgtcagctgg tcattttgaa gattgttttt accaacaaga atgagcgttc cgtcagaaga
    50941 aaagtattga tcaggctgag atggtttctt acgtttttgt ttttttaagt tcttcttttt
    51001 caggtatcct tctgaagtca attcttcttt aattgcttcg atatccattg ggccggcaat
    51061 ttccagttga gataagacag attcaagata ttggatttca tctttggctt cttggatttg
    51121 ttcgccaatc agcttaacag cgttcttcag cttttggtat cgatggaaat atttctgtgc
    51181 attttgattt ggtgtcaatg ccggatctag tgctattttg attggccgat cttcttcata
    51241 ataattaggt aaaacaactt cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag
    51301 tagttcgcca tttctacggt aattctcagc gttttcggat tctttgagtg tttgttcacg
    51361 ttttttcaat ttatttttat ttcgttttag ttcattttcg atttttcgaa tcagttctcc
    51421 gccttgttgt tttgcccgat ctttctctgc tttttcgtga taatagctat ctaataattg
    51481 actgagtgtt ggataagctg ttacagcaga tgcctgttcg gacaatacct gataagcaat
    51541 cggtgtgaaa aaatctttat tttccgtttc gtaaaaagta ggaataggct gatggctgat
    51601 ggctgagaaa aattcgtccc atacaaccat cttttcatta ggacgttcca gtaatctttt
    51661 ggtcagctct tgagcgatat cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg
    51721 atctagttca gtttgggaaa gccgctgaaa gattttttct ttctcggagc taaatgggtt
    51781 caagacctct tgttttggcg gagcaacata ttctacacca ggaagcaaag aacgataagt
    51841 gttttgagag cttccaatgt gtttgatcgc atccagtatt tttccagttt ctcgattaac
    51901 taagacgatc gtactatgac gtcccattaa ttcaacgatc aatatgatat tttgtagatc
    51961 acccaactcg tttcgtttag caaagtggaa atggatcact cgatcatttt cgatttgttc
    52021 gatgtcttct aaaatagcgc catccaaata ttttcgaagc atcatcacga agttaggcgg
    52081 attatcagga ttctgataat cgatttgggt aatctgtaca cgagcataac ttgggtgcgc
    52141 agataataat aatcgatggt ttttgccgcg tgaacgaatc accagcacga tttcattttc
    52201 ataaggctga tggattttcg agatccggcc agatagtaac gtttcacgca attcgttgac
    52261 catcgcgtgg gtaaatacac catcaaagga catggttcat tcctcatttc ttttcataag
    52321 tatattcatt ataacgaaaa aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag
    52381 tctagaaaaa tcttggacta attacataaa aaacagtgtt tctatcgttg aaatccaaat
    52441 ttttaggt
//
LOCUS       DAZKCW010000015        51604 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000015 DAZKCW010000000
VERSION     DAZKCW010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.015"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            25..696
                     /locus_tag="ACG84Z_000952"
     CDS             25..696
                     /locus_tag="ACG84Z_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFP9161811.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="ACG84Z_000953"
     CDS             755..1195
                     /locus_tag="ACG84Z_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161812.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="ACG84Z_000954"
     CDS             1207..1875
                     /locus_tag="ACG84Z_000954"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFP9161813.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="ACG84Z_000955"
     CDS             1939..2562
                     /locus_tag="ACG84Z_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFP9161814.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="ACG84Z_000956"
     CDS             2618..3004
                     /locus_tag="ACG84Z_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFP9161815.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="ACG84Z_000957"
     CDS             3217..4608
                     /locus_tag="ACG84Z_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFP9161816.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5219..5587
                     /locus_tag="ACG84Z_000958"
     CDS             5219..5587
                     /locus_tag="ACG84Z_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFP9161817.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5767..6708
                     /locus_tag="ACG84Z_000959"
     CDS             5767..6708
                     /locus_tag="ACG84Z_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFP9161818.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6777..7508
                     /locus_tag="ACG84Z_000960"
     CDS             6777..7508
                     /locus_tag="ACG84Z_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFP9161819.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7652..9832
                     /locus_tag="ACG84Z_000961"
     CDS             7652..9832
                     /locus_tag="ACG84Z_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFP9161820.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9852..10334
                     /locus_tag="ACG84Z_000962"
     CDS             9852..10334
                     /locus_tag="ACG84Z_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFP9161821.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10350..11111
                     /locus_tag="ACG84Z_000963"
     CDS             10350..11111
                     /locus_tag="ACG84Z_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFP9161822.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11242..12576
                     /gene="murC"
                     /locus_tag="ACG84Z_000964"
     CDS             11242..12576
                     /gene="murC"
                     /locus_tag="ACG84Z_000964"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFP9161823.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12883..13368
                     /locus_tag="ACG84Z_000965"
     CDS             12883..13368
                     /locus_tag="ACG84Z_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFP9161824.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13361..14044
                     /locus_tag="ACG84Z_000966"
     CDS             13361..14044
                     /locus_tag="ACG84Z_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFP9161825.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14170..16815
                     /gene="polA"
                     /locus_tag="ACG84Z_000967"
     CDS             14170..16815
                     /gene="polA"
                     /locus_tag="ACG84Z_000967"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFP9161826.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16860..17696
                     /gene="mutM"
                     /locus_tag="ACG84Z_000968"
     CDS             16860..17696
                     /gene="mutM"
                     /locus_tag="ACG84Z_000968"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFP9161827.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17660..18289
                     /gene="coaE"
                     /locus_tag="ACG84Z_000969"
     CDS             17660..18289
                     /gene="coaE"
                     /locus_tag="ACG84Z_000969"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFP9161828.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            18341..18673
                     /locus_tag="ACG84Z_000970"
     CDS             18341..18673
                     /locus_tag="ACG84Z_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFP9161829.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18985..19476
                     /gene="nrdR"
                     /locus_tag="ACG84Z_000971"
     CDS             18985..19476
                     /gene="nrdR"
                     /locus_tag="ACG84Z_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFP9161830.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19499..20872
                     /locus_tag="ACG84Z_000972"
     CDS             19499..20872
                     /locus_tag="ACG84Z_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFP9161831.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20872..21798
                     /gene="dnaI"
                     /locus_tag="ACG84Z_000973"
     CDS             20872..21798
                     /gene="dnaI"
                     /locus_tag="ACG84Z_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFP9161832.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21927..22367
                     /locus_tag="ACG84Z_000974"
     CDS             21927..22367
                     /locus_tag="ACG84Z_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFP9161833.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22511..23212
                     /locus_tag="ACG84Z_000975"
     CDS             22511..23212
                     /locus_tag="ACG84Z_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFP9161834.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23209..24330
                     /locus_tag="ACG84Z_000976"
     CDS             23209..24330
                     /locus_tag="ACG84Z_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFP9161835.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24345..25577
                     /gene="pepT"
                     /locus_tag="ACG84Z_000977"
     CDS             24345..25577
                     /gene="pepT"
                     /locus_tag="ACG84Z_000977"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFP9161836.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25709..26617
                     /locus_tag="ACG84Z_000978"
     CDS             25709..26617
                     /locus_tag="ACG84Z_000978"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFP9161837.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26652..26924
                     /locus_tag="ACG84Z_000979"
     CDS             26652..26924
                     /locus_tag="ACG84Z_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFP9161838.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26935..27981
                     /locus_tag="ACG84Z_000980"
     CDS             26935..27981
                     /locus_tag="ACG84Z_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFP9161839.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            28232..30841
                     /gene="clpB"
                     /locus_tag="ACG84Z_000981"
     CDS             28232..30841
                     /gene="clpB"
                     /locus_tag="ACG84Z_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFP9161840.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(30992..31678)
                     /locus_tag="ACG84Z_000982"
     CDS             complement(30992..31678)
                     /locus_tag="ACG84Z_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161841.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(31656..32150)
                     /locus_tag="ACG84Z_000983"
     CDS             complement(31656..32150)
                     /locus_tag="ACG84Z_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFP9161842.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(32170..33390)
                     /locus_tag="ACG84Z_000984"
     CDS             complement(32170..33390)
                     /locus_tag="ACG84Z_000984"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9161843.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33537..35372
                     /gene="lepA"
                     /locus_tag="ACG84Z_000985"
     CDS             33537..35372
                     /gene="lepA"
                     /locus_tag="ACG84Z_000985"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFP9161844.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            35568..36479
                     /locus_tag="ACG84Z_000986"
     CDS             35568..36479
                     /locus_tag="ACG84Z_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9161845.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            37475..37726
                     /locus_tag="ACG84Z_000987"
     CDS             37475..37726
                     /locus_tag="ACG84Z_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161846.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            37839..38081
                     /locus_tag="ACG84Z_000988"
                     /pseudo
     CDS             37839..38081
                     /locus_tag="ACG84Z_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708076.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            38171..38410
                     /locus_tag="ACG84Z_000989"
     CDS             38171..38410
                     /locus_tag="ACG84Z_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161847.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            38557..42840
                     /locus_tag="ACG84Z_000990"
     CDS             38557..42840
                     /locus_tag="ACG84Z_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HFP9161848.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            42939..43304
                     /locus_tag="ACG84Z_000991"
     CDS             42939..43304
                     /locus_tag="ACG84Z_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161849.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            43306..43758
                     /locus_tag="ACG84Z_000992"
     CDS             43306..43758
                     /locus_tag="ACG84Z_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161850.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            44207..45682
                     /locus_tag="ACG84Z_000993"
     CDS             44207..45682
                     /locus_tag="ACG84Z_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HFP9161851.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            45705..46016
                     /locus_tag="ACG84Z_000994"
     CDS             45705..46016
                     /locus_tag="ACG84Z_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161852.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            46377..47633
                     /locus_tag="ACG84Z_000995"
     CDS             46377..47633
                     /locus_tag="ACG84Z_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFP9161853.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            47630..48175
                     /locus_tag="ACG84Z_000996"
     CDS             47630..48175
                     /locus_tag="ACG84Z_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161854.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            48176..48676
                     /locus_tag="ACG84Z_000997"
     CDS             48176..48676
                     /locus_tag="ACG84Z_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161855.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            49035..49313
                     /locus_tag="ACG84Z_000998"
     CDS             49035..49313
                     /locus_tag="ACG84Z_000998"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161856.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVMQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            49333..49677
                     /locus_tag="ACG84Z_000999"
     CDS             49333..49677
                     /locus_tag="ACG84Z_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161857.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            49696..50607
                     /locus_tag="ACG84Z_001000"
     CDS             49696..50607
                     /locus_tag="ACG84Z_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFP9161858.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            50686..>51604
                     /locus_tag="ACG84Z_001001"
     CDS             50686..>51604
                     /locus_tag="ACG84Z_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFP9161859.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVIT"
BASE COUNT        17573 a         8597 c        11060 g        14374 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     4801 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
     4861 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
     4921 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
     4981 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
     5041 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
     5101 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
     5161 tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagga ggaaacagat
     5221 gtttacgaat gaaataaaaa tcatgcttta tgtggacgat gtagaaaaaa atgcaacgtt
     5281 ttggagagca gttggctttg cggaaaaaga tcgtcaagaa atggatggga cgcttataat
     5341 tgaagtagga gttgaggaca gtcaaacctc atttctgtta tatgatcgag catttgttga
     5401 gtcccattca cctggcacag ctactagtgc cccatctttg atgttttaca gtaaagatat
     5461 ctttggacta tataaaaaaa tgcagacgca atcagtcaca ttaggtgata tggtacagct
     5521 tggagaagaa tatgtcttta actttgctga tcccgatggc aactactttg cggttacagg
     5581 taaataatag aaataaagac tttgtttttc tgtgcgaaac aggaaagcga agtcttttta
     5641 attcaaataa taatattatg taaacaaaaa actttccatg cgtaattata cacaagcaaa
     5701 taaatcgtca aatgcgaacg ccttctttat actgtttagg aacgaaaaga aggaaggaag
     5761 aaatacatgg attatcaagt actgctttat tacaattata caaaaatcga agaaccagag
     5821 gaatttgcca aaaatcattt agccttttgc aaatctttgg atcttaaagg tcgtattcta
     5881 gtagctgaag aaggaataaa tggtactgtg tctggaaccg ttgaaaacac gactgcctat
     5941 atgaaagcaa tgaaagctga tcctcgattt gctgatacga tgttcaagat cgatccaagc
     6001 gaaggacatg cctttaagaa gatgtttgta agataccgtc cagagcttgt aagtttaaag
     6061 ctagaagagg acattgatcc aaaccaagtg acaggtgcct atctttcacc gcaagaattt
     6121 aaagaagcta ttttagatga acagacagtg gtgattgatg cacggaatga ttatgaatat
     6181 gacttgggac attttcgagg ggctgtacgc ccagatatac gcagttttcg agagcttcca
     6241 gactggatcc gcgagcacaa agaagaattt atggaaaaac gggtagtgac ctactgtact
     6301 ggtggcattc gttgcgagaa gttttctggt tggcttgtcc gtgaaggatt caaagatgtc
     6361 ggacagctgc atggcggtat tgctacttat ggtaaggatc ctgaagtcca aggagaatta
     6421 tgggacggca agatgtatgt gtttgatgaa cggatcgctg tcgatatcaa ccaagtagat
     6481 aaacaaatcg tcggtcgcga ctggtttgac ggaacaccat gtgaacgata tatcaattgt
     6541 agcaatcctg agtgcaatcg tcagattctt gcttccattg aaaatgaaga aaaacattta
     6601 ggagcatgta gcatagagtg tgcgaaacat ccgcgcaatc gctatgttca agaccatgga
     6661 atctctccag aagaagcaga actgcggttt acagctttaa ttaaatagaa aacaatagtt
     6721 ttgattgtcg accatttcca atatgcgcta tactagcgtt gaggatggtg atccacatga
     6781 aatcattgat ttatgctatt ggggatgtcc atggcaaaca tgagcttttt gaaaaactta
     6841 ttcactatta tgatccaaag atccatcagc ttgttttatt aggggatctc aatgatcgag
     6901 gtcctcgtac aaaagaatgt tttttattag gaaagcaatt agtcgaagaa acaggagcca
     6961 tttacctccg gggaaaccat gaagaatatt ttttgcaatt tctgcaatca ccggaggact
     7021 ggtatgcgcc ttatatgaga aatggtggaa aagaaacgtt tgaaagcctg attcacccag
     7081 gggcatcgga ggaatactcc ccaactgaaa tctcgatgat gatccaatcg agatattcag
     7141 aactgattaa atttttagtc cagcgcccct tgtattatga atgggaaaat tatctttttg
     7201 tccatgccgg tgtggatttg acaaagaaag actggcgtaa gacaagtcta agagacttta
     7261 tttggataag ggaaccattt catgaaggga aaaacaatac aggtaagaca attgtatttg
     7321 gacatacgat tacaccaatg ctccatggag atatgcagac aacagacctc tggattcagg
     7381 atcataaaat cggaatggac ggtggggctg tattcggagg gtcattgcat ggggttgttt
     7441 ttgacaagga aggtattctt caagatattg aatatcagaa caacgaagga ccttggcatg
     7501 gaatctgact aatggaaaga atgaaggagc tgtgactttg ttgcggctct ttttattttt
     7561 atagagaata ttgtttcttt cagtagttta acccaggata aaaagtatga tagaataaag
     7621 aagcaatttt tagcagaaaa gaggcatttt aatgacggaa aatttgaacc agacgatcat
     7681 tcagcttgta caaaaagaac tttcagacta tcgtcctaag cagttgacta ctgtacttaa
     7741 tttgttaaat gaaggaaaca ctgttccttt tatcgcgcgt taccgaaaag aaatgactgg
     7801 aagtcttgat gaagtccaga ttcgtgaaat cgaagagcgg tatgcctatc ttgaaaactt
     7861 agaaaaacgt aaaactgaag tgattcggct aatcgatgaa caagggaaac tgactcccga
     7921 gttagaagca gaaatcaccc aagccgtgaa aatgcaacaa gtggaagatt tgtatcgtcc
     7981 atacaaacaa aaacgacgga caaaagcaac gattgctaaa gaaaaaggac ttgaaccact
     8041 cgcgaagtgg ctgatgcagc ttacagatgg agaggtgcaa tctgaagcag aaaaatatat
     8101 tgacaaagaa aaagaagtct cttctgccga agaagcgttg cacggtgctc atgagattat
     8161 tgctgaacaa gtcagcgata atgcaaaatt tcggacttgg attcggtctt atacgtataa
     8221 caaaggtatg tatgtcagca atgtcaagga tgagcaagca gatgaaaaag gcgtatatga
     8281 aatgtattat gactttgcag aacccgtcca taaaatggtt tctcatcgaa tattagctac
     8341 taatcgtgga gaaaaagaag atattctgaa agtattcttt caagtagatg aagcagcaat
     8401 tttagcttac ttggatcgcc aaatagtcaa aaatcctgcc tctccttctt cttcattcgt
     8461 cagagaagcc tatcaggata gttataaacg ctttattcag ccagcaatcg agcgagaact
     8521 gcgcaatgaa ttgactgaaa aggcagatga gcaagcaatc gctattttcg gcgaaaacct
     8581 ccgtaatctt ttgttgcaac cgccactaaa aggtaaagtt gtcctgggat ttgatccggc
     8641 ttatcgtact ggatgtaaac tagcagtcgt agatgcgaca gggaaagttt tagcaatcga
     8701 agttatttat cctcataaac ctgcagcgca agcaaaaaga gaagctgctg gaccagcttt
     8761 tatccaatta attaataaat atcaagtaga tatggtagct atcggaaatg gtacagccag
     8821 tcgggaatct gaactttttg tggctgagca gttgaaatcc gccgaccata aaacctatta
     8881 cgctatcgtc aacgaagcag gcgcttctgt ttactccgct agcgaaattg cacgaaaaga
     8941 atttccgcat ctacaagttg aagaaagaag tgctgtttct attgcccgtc gcctgcaaga
     9001 tcctttagct gaattagtca aaatcgatcc taaagctgtc ggagtaggcc agtaccaaca
     9061 tgacgtttct caaaaacgtt tggctgaaca attggatttt gttgtggaaa cagcggttaa
     9121 ccaagtaggt gtggatgtga atacagcaag cccgcagctc ttgcagcata tatcaggatt
     9181 gaataaaaca actgcccaaa acattgtcat ttatcgtgaa gaaaacggag aattcaccgc
     9241 acgaactcaa ttgaaaaaag tgccacgctt aggaccaaaa gcatatgaac aagcaatcgg
     9301 attcttgcga gtccctggtg ggaaaaacat tttggacaac acaggtatcc atcccgaaag
     9361 ttattctatt gcaaaagaaa tattaacttc agtccaactt tcagaaaaag agcttggtac
     9421 agaagaagca gtagaaaaat tgacacgatt atccgtagag aaactggctg aaagcctatc
     9481 agtcggagaa gaaacgttag ccgatatttt agctgggctg acacaacctg gacgagatat
     9541 gcgtgatgag atgccagcgc ccttattacg tacagatgta ttgagtatgg aagacttgaa
     9601 accagggatg gaattgactg gaacggtccg taatgtcatt gacttcggcg catttgttga
     9661 tatcggtgtg aagcaagacg gacttgtcca tatatcgaaa ctcagcaaaa aattcgtcaa
     9721 gcatcctaca gatgtcgtgt cagtaggaga tatcgtaaca gtttggatag aacaagtcga
     9781 tacgaaaaaa ggcagaatca gtttgacgat gctttcccct tatgaagagt aacaatgagg
     9841 agtaacaaaa attgacacaa gaagaactgc agcagttagt agaagagata tcattaaaaa
     9901 gcttccagct tcctttcaag caccaagcaa tgttcaatcc acgcttacgt acaactggcg
     9961 ggcgctatca tttaaacgat catcatttag attttaatgc gaagctattt gaagagtcag
    10021 acgaagagac gattgcagga atcatcaaac atgaactttg ccattatcat cttcatctag
    10081 ctggaagagg gtatcagcat aaagatatgg atttcaagta tcttttgaaa aaaacaggag
    10141 ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa gatggagtat tatcgatgcc
    10201 aagattgttc tgccacgatc tgccgcaaga gaagaatcga tgtacgcaaa tatcgttgtg
    10261 gaagatgtca tggagaaatc aaatggattg agacaaaaag agaagacttt aatgaagcac
    10321 aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag tgagcagagg aatctaaaag
    10381 actggaatca gctattaaat tttttagccg cacctgaaga gggaaatttt gaggaactga
    10441 cggcacctac acttatttta gctggaaact gtcttcctat cttagctgat aaagcagcac
    10501 aaatgtattt aaatggccaa gtagatcaat tgtttttggt cggaggggtg gggcatgcga
    10561 ctagaatcct ttatgagaat tttgaaaagc aaggatttca ttttgaagat ggcatgagtg
    10621 aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga tttgcccgat aaggcttttc
    10681 tgatagaatc gaagtctaca aattctggag agaacgccac tttttcactg gagattcttc
    10741 attccttagg agctgtacca gaaaaaatct tattgatgaa tgatccgaca ctgcaacgca
    10801 ggactcgagc aacttttgag aaagtatggc aaaatgaaca aactattttc gcgaatgctg
    10861 tgccatttgt gccggaaatc cttcactttt ctgaagagat catctttaca gcaaaagaac
    10921 tgaatcatca atggcctaag gaatatttcc atgcgctagt attaggagaa atggaacgtc
    10981 tccatgacga tgagaacggc tatggtccga aaggaaaaga ttttattcct cacattgata
    11041 tatcagagga agtttggtct tcttacacca gaattaaaga gtcaataaaa acggattttt
    11101 ctcgtacttg accattttag caagcgaatc ctcctttcca aataaatttg gttgaaattt
    11161 tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa tagctaaaag aatggacgct
    11221 agataagaga agaggattca aatggaaaat caaaataaat tgtatcattt tgttggtatc
    11281 aaaggttcag gaatgagctc cttggctctt gttttacatg aacaaggtct aaatgtccaa
    11341 ggatcagaca ttgaaaaata tttctttaca caaagagatt tagaaaaagc aaatatcacg
    11401 attctgccat ttaacgcaga taatgtaaaa ccagggatga cgatcattgc aggaaatgca
    11461 tttcctgatt cacatgaaga aatccagcga gcaaaagaat taggtttgga agtgattcgc
    11521 tatcacgact ttattggtca ttttatccaa aattatacga gtatcgctgt aacaggctct
    11581 cacggaaaaa caagtacgac tggactgctc tctcatgtat tgagtggtgt ccgtccaaca
    11641 agttatctaa ttggagatgg aacaggacat ggtgatccgc aagcggaatt cttttcattt
    11701 gaggcctgtg aatatcgccg tcatttcctt gcctattcac cagactatgc aatcatgacc
    11761 aatatcgatt ttgatcatcc ggattattat acaagtatcg acgatgtatt tacagctttc
    11821 caaacaatgg ctggacaagt gaaaaaagct atttttgcgt atggtgacga tgcttattta
    11881 cgcaaattaa aagcaaatgt gccgatttat tattatggtg tcacagaaaa cgatgatatc
    11941 caagcacgaa acatcgaacg cacaacttct ggttctgctt ttgatgtcta tcatggggat
    12001 gaatttgttg ggcacttcac tgtaccagca ttcggtaaac acaatatctt aaatgcttta
    12061 ggtgttattg cagtagctta tttcgaaaaa ctggatctga aagaagttgc agaagaaatg
    12121 ctgactttcc caggagtaaa acgtcgattc agtgaaaaga tcgtagcaga catgaccgta
    12181 gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa cgattgatgg cgcacgccaa
    12241 aaatatccag ataaagaaat aattgcagtt ttccaacccc atacgtttac gcgtacgatt
    12301 gcattgatgg atgaatttgc agaagcactt gatttagctg ataaagttta cttatgcgat
    12361 atttttggtt cggctcggga agaacaagga aacgttaaga ttgaagacct tggagcgaaa
    12421 atcaaaaaag gtggagaagt catcaaagaa aataatgtat ctccattgtt agattatcat
    12481 gatgcagtag taatcttcat gggtgctgga gatgttcaaa aatttgaaca agcgtatgaa
    12541 aaacttttaa gcagcacgac gaaaaatgta ctgtaataca attactgcag tgtccttata
    12601 aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc cccttttttg caacttatga
    12661 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aatcaaatca aaaacatgag
    12721 aagctgtttt ttcttggctg ttcttattat ttgatgcagg acagcttttt cacgacctct
    12781 gtaaactata ggaatctgtt aaatcaaggg agcagaactt gccttttacg ctacttttgg
    12841 tacaataatg tatgattaaa aataaactgg agggtttcta tcttgaacat aggtaagccg
    12901 agaaaactag gaaaaacaat aaatgaaatc gaggaaggcg actcgttatc cttaacagaa
    12961 tctattgaag ataaccagct tttgctgtat ttgggattga cgaatgatgc aaatcctttg
    13021 tatatccaac atgactttgc acaaaaaaca gaatatcaac agccaatcgt tccatcagtg
    13081 atgctgatgg ggatcatcac aagtgcaatt tcaaagcatc ttcctggacc aggatcacat
    13141 gttgtcaatt tttctgtcaa ttttattgaa ccggttttcc attatgaaac actgactttt
    13201 cagtttgagg tcataaaagt agataagatg aaggatgtgg tgacgatttc tgtagaagcg
    13261 gagaatacga acgaagatcg tgtgttggat gctgtcgtta tggtccaacc gccacaagtt
    13321 cctgaattgg aaatagcaat cgaaagtgaa ggtgaattga atgaataatc caagtacatc
    13381 aatgtcaggt atcaatcgtt tttatgcaaa agtttatgga tttttaggta tgggacttgc
    13441 ccttagtgca gtcacttctt acttggctct ttgggtattt cctttgcaat tagcaacttt
    13501 tatcaataat tttccactag gctttgtggg tctgtggatc gttgaactga ttttagtaat
    13561 ggttctaggc gtaaaagcac aaaagaatcc gagcttagca atcggtggat ttattgccta
    13621 ctctcttttg aatggcataa cattagcggt tactcttgca tactacgata ttggaacagt
    13681 aacgcaagct ttcttgacag ctactttgat gttcatgggg atgtctgttg tcggagtaac
    13741 aacaaaaaga gatcttagcg gggttggaag agcaggacag gcagctttaa tcggagtgat
    13801 cattgcacta gtcttgaaca tcttcatttt gagaagtagc gtagttgagc tgttcatctc
    13861 cctactgtta gtcgtcatct ttgcagggat tacagcttat gataaccaaa gcatccgtaa
    13921 tatctatgtc cagacaaacg gaacagcaca tagtggaatt gctgtattca tggcattgaa
    13981 gctgtatttg gactttatca acttgttctt ggcgtttctg agaatctttg gacggaacaa
    14041 ctaaaaaaga aaaaaattca tcagttgggg ctataccgaa ttatttggta tggtcccgct
    14101 ttttcttttc gcattccgca ggattctttg ttagaatgaa taagaacttt acagtaagga
    14161 gttaagaaga tgacaaaaaa taaattatta ctcgttgatg ggaacagtgt ggcttttcgc
    14221 gcattctttg cgcttcacaa ttctcttgaa cgtttcaaaa atagaaacgg tcttcataca
    14281 aatgcaatct atgcattcaa tacgatgttt gaaaatgtta tgcaaaaaga gcaaccgact
    14341 catgttctgg ttgcgttcga tgcaggaaaa acgacttttc ggacagaaat gtatgcggag
    14401 tacaaaggtg gaagatccaa aacacctggc gaattcaaag aacaaatgcc atatatacgt
    14461 gatttgttga caggactagg ggtacagtat tacgaattgc ccaattatga agcagatgat
    14521 attatcggta ctttggcaga aaaagtagac aaagatcaat ttgatgtcgt cgtgctttca
    14581 ggtgatcggg atttgactca attagctagt aaagaagtaa aagtggatat cactgtaaaa
    14641 ggtgtcagcg atatcgaaag ctatacacca gaacatgtag cggaaaaata tgatgggttg
    14701 acgccaaaac agattattga catgaaggga ctagccggag atgcctctga caatatcccc
    14761 ggtgtgacta aaatcggtga aaaaacagct atcaagctat tgaaacaata tggctcagtc
    14821 gaaggaattt atgaacatat cgatgaaatg aagcaaagca aaatgaaaga aaatctgata
    14881 aatgacaaag agcaggcttt cttatcgaaa aaattggcga ccatcaatac ttcagcgcct
    14941 gtggatgtct ctatcgactc attgaagtat gaagggaaaa atctcgataa actcgttccg
    15001 ttttataaag aaatggattt caatcagttc ctttctaaat tgaatatcgt agaagaagaa
    15061 gtaaaaatgg atgatatttt gtttgaagtc gttcatgaat tcaaagagga aatgtttact
    15121 acggatatgg cgttgtacgt ggaaatgatg ggcgacaatt atcatacaga ggaaatcgtc
    15181 ggagtagcgt gggggacaga aaagaaaatt tatgtcacga acgatctatc tgtattcgaa
    15241 aaccgagcgt tccattcttg gatcactgat ccgactcggc tgaaaaaagt atatgatgcg
    15301 aaacgaactt atgttgcttt aaaccgctat actggaaaaa cgaaaggaat cgattttgat
    15361 gtcttgctag gtgcatacct tctcgatacg aatgaaaaaa gcacagatat cgaaggaata
    15421 gctgctcatt acggatacaa cgatatccaa tcagatgaag ctgtatacgg caaaggggcg
    15481 aaaaaaggtt taccagaaga agaggaactc ttttttgctc atttagcgcg aaaagtagct
    15541 gcaatcaatg cgttgacacc aaaattgagc caagaactgg cagaaaaaaa ccaagaagat
    15601 cttttccgga aaatggaact gccattgtct atcattttgg cagagatgga aataagcggg
    15661 atcaaagtag atgcgactcg cttacaagaa atgaagggcg agttctctgc tcgcttaaga
    15721 gagatcgaac aaaaaatcta cgaagaagcc ggcgaagaat tcaatttgaa ttcaccaaag
    15781 caattaggag tgatcttatt tgaaaaaatg ggattacccg ttatcaaaaa aacaaaaact
    15841 ggatattcca cagccgtaga tgtactggaa cagcttcgtg aacaagcacc aatcgtagag
    15901 gatatcctca cctatcgtca aattgcaaaa attcaatcta cctatgtcga gggactgctg
    15961 aaagtgatcc aatcagatgg aaaagtgcat acccgttatg tccagacatt gacccaaaca
    16021 ggacgattaa gctctgttga tcctaatttg cagaacatcc cgattcgatt agatgaaggg
    16081 agaaagatac gtcaggcatt tgttcctaga gaaaaagact ggctgattta ttcttctgac
    16141 tattcacaaa tcgagttacg cgtacttgcg catatctcaa atgatgaaca tttgaaagct
    16201 gccttcctag aaggtcaaga tatccatgcc agcacagcga tgcgtgtatt tggaatcgaa
    16261 aaggcagagg atgtcacacc aaatatgcgt aggcaggcaa aagcagtgaa ttttggtatc
    16321 gtgtatggca tctctgatta cggactttca caaaatctag gaatcagccg aaaagcagca
    16381 cagcaataca tcgatacgta ctttgaaaaa tacccaggtg tcaaagaata tatggaaaga
    16441 atcgtacgcg aagcaaaaga ccaaggctac gtcgaaacgc tgtatcaccg ccgtcgatat
    16501 ctgccagaca tcaattcaag aaattacaat atccgttctt ttgcggaacg aacagctatc
    16561 aatacaccaa tccaaggaag tgctgctgat attttgaaaa tcgcgatgat cgaattggat
    16621 aaacgattaa aagaaacagg tcttcaagct acgatgctgt tacaagttca tgatgaactt
    16681 gtcttcgagg taccggaaaa agaacttgaa tcattagata aattggtgaa ggaagttatg
    16741 gaacaagctg tttctcttca tgtaccactg atcactgaca gcagttgggg aaaaacgtgg
    16801 tacgaagcaa aataaacatt gtttaagaca gagcaatata atgaaggtga aaagaaaaaa
    16861 tgccagaatt accagaagta gaaaccgttc gtaaaggatt ggaacggtta gtagtaggaa
    16921 aaacgattca aaaagttcag gtcttgtggc ccaagatcat cgagcaacca gagacaccca
    16981 tctttgaggc ttctcttgtt ggcgaaacca tccaatccat tggacgtaga gggaagtttt
    17041 taatttttca tctcgatcat tgtgaactga tctcacactt gcgaatggaa ggaaaatatc
    17101 aatttacgaa agaaaataca ccaatcgata aacatacgca tgtacttttc ttttttgagg
    17161 atggaagcca acttcgctac aacgatgtac gaaaatttgg tcgtatgaca atcgtcgaaa
    17221 aaggagcaag tgcaacttac cgaggaatca tgaaattggg acctgagcct ttgccagata
    17281 gcttcttatt agcagatttc gcaaatggac tgaaaaagtc ccacaaagca atcaagccat
    17341 tgctgctaga ccaacgtcta gtgactggtc taggtaatat ttatgtagat gaagcattat
    17401 gggaagcgaa gatccatcca gaacaaccgg cgaacacact gcgccccaaa gaggtagaac
    17461 aattacgtct atcgatcatt gatgttttgg atcgtgcaat agaagccgga ggtaccacga
    17521 ttcgcagtta tttgaatgca ttaggagaat caggcggatt tcaagtagca ctgcatgtct
    17581 atcagcaaac tggcaaacca tgtatacgtt gtggaacgcc gatcgtgaaa acaaaagtgg
    17641 cacaaagggg gacgcactat tgtccgaatt gtcaaaggct aaaaatcgca aagtaggatt
    17701 tgttttaggt ttgacgggtg gaatagctac cggtaaaagt acggcagcca aagtctttca
    17761 gtctcatgga tttcctttga tcgatggcga tgtgattgcc agagaaactg ttgagcctgg
    17821 aacgcttgct ctgaggaaaa ttgtatcagt gtttggccaa gaggtattgc agcctgatgg
    17881 gcaactagat cgagggaaac ttgggatgat tgtttttcca tcaaaggaaa aacggcaaaa
    17941 acttgatcag ctattagatc cgtttatccg aaaagcgata aaagatcaaa tcgcctctct
    18001 aagttccaat catcctttag taattgtaga tatcccattg ctctacgaag gtcattatga
    18061 ccactatatg gatgcagtag ctgtcgttta tactacgcca gaaactcagc ttcagcgttt
    18121 gatgaaacgt aatcaactga cgctagaaca agcgcagcag agaattagta gtcaacttcc
    18181 aatcgaagaa aaaaagcagc gtgcggatat tttgttcgac aacaatggaa caaaagaaaa
    18241 acttgtggga caaatcgaaa attggctttt tgctaatcgc tttctttgag tatctgtgtc
    18301 aattttgcta tcctgagtat atagaaagtg agggatagcg atgggatcat taaaaaatca
    18361 aaaggataaa gtcgtaggta acgcaaaaga aaaaatcggc gagatgctca ataaagaaaa
    18421 tctaatcgat gaaggtcgta cgcaatcaga aacagcagaa gaaaaagaaa agcagtacca
    18481 agcaagaatc gatgaaatag aagaccagca ggcagaagaa gaagcgaagc ggcaagattt
    18541 gactcaagaa cgaaaaaatc cgacacctga tcgtagtaaa acaccgctcc cagaaagtga
    18601 ccacattccc gatgagcaaa aaatcgagga acagcgaatg aaacactata caggaatcga
    18661 agagaagtta taaaatagta aaaaatcgag atgtgacttg aagcagatga gaaggtgttc
    18721 atctgcttca agttttttgt gctagatgac taaatcagct tttgtgtaag ttatttctca
    18781 gtaatcaagg tgatcagtat tggaaaattg aaatttagta aggacagggg acacaattac
    18841 gcatgaaagt agaaaaaatt gttcttatat ccgtgttttt tgggtaggac agtcgcgttt
    18901 gtgatttgtt tcgtgttata atacaactag ttgtaaagaa agacacatcc tttatataaa
    18961 atgcgatgca agaggtgaga caaaatgaga tgtcccagat gtcaacataa taattcacga
    19021 gtaatcgaca gccgtcaagc agatgatgga cgtgcgatcc gtcgccgtcg cgaatgtgag
    19081 aattgttcgt tccgattcac tacatttgaa cgaattgaag ctgctccgtt attagtaatc
    19141 aagaaaaacg gggaacgcga agagttcaat cgcgataaaa ttttaagagg actcatccgt
    19201 tcagcagaaa aaagacctgt agctatggaa caaatggaac aaatcgtcaa ccatgtcgaa
    19261 aaccgcgtac gcagtctcgg agaaaacgaa gtatcgacga atctaattgg tgaatatgtg
    19321 atggaagatt tagttgattt agacgaaatc gcttatattc gttttgcaag tgtttatcgc
    19381 cagttcaaag atatgtctgt tttcttaaaa gagttgcaag atatcgtgga taaagcaaaa
    19441 gaaaataata aagagaataa taaagaaaac aattaagaaa caaaaaggag gcatttcctt
    19501 ggaaaatgct tggaaagagc ttcaaccaaa aaatatttac caaggaagaa aagcggctcc
    19561 gctgagagaa gacagcaaga acgccttgct gtatctttat cagccactaa tcggcggaga
    19621 agccttgagt atctatttca ccctgttatc agaaatctct caagaatctg gcaaaggtcc
    19681 tgaagggatg catgcagatc tgcttagtag tctaggctgc ggtatcccgc aattttatga
    19741 tgcaagaaaa aagctagaag gaatcggctt actggatgtt tattttaaag aagatagtga
    19801 tctgggacct cgttttattt atgagctgtt agaaccactc attcctaaag catttttcaa
    19861 agactctgtt ctggcttttc ttcttctgga aaaagttggt gaacgacgat tccagaagct
    19921 tacccaattc tttgaaccta aaaggcatac agcagaggga tatcaaaaaa tcacaaaaaa
    19981 atttttagat gtttatcgct tcaatgaagc agtgtacgct gctaatcaag aaaacatcga
    20041 atcgctgaat aaatcttttg aagaatctga atcagtagca ttacttgaag cagattcgac
    20101 attcgattgg cagtttttga atgattggct ggcaaaaaaa catattgcaa gtcttgatga
    20161 tccaatcatc aaacaagtcg acatgtatca tcagctttac ggtttcgatg aattgacact
    20221 tggcgaactg atcagtcaat cttatgactt tagtgaacaa aaagtatctg aaaaagaact
    20281 gcaaaaagcc attttggcaa tgcagagacg tccggtgaag caaacaaaag aaacagttgc
    20341 ggtttctgaa aacagtaatg aaccctcgtc aaacgaacat ttgacaaacg cagcgcttca
    20401 gctgataaaa gaagcacaga gcattccacc gatgaaatat ctggaagcaa tcaagtcaga
    20461 aaaaggcgga tatgtttcta aacaagaaaa ctggttactg caagatcttg tttctcaatc
    20521 aggtctttcc agtagcgtga tcaatgtttt gctgaattat gtactagtga tcaagaataa
    20581 tgctagctta aatgccagtt atgtaaatac agtggcaaat gaatgggcac aaaagaaaat
    20641 cgccacagca gaagaagcga tccagcacat tcggcaaata agtaatcaag caaaacaatc
    20701 aaaacaaaag aagcaaacaa attatcaaac tggcaagcga aatgttcgac gggaaaagct
    20761 tcctgattgg gtcaaccagc caaaagatga aaaacagatc agcagcgaga aaaaagcaga
    20821 gattgaccgc cgttttaaag aatacctggc aaaaaaggag ggtgatatct agtggaagac
    20881 gtaggcaaag aattgaagag gatcatcagc aaacgcaatt atcaagaaaa gtatgctgaa
    20941 atgatcgctg aagtcttaaa tgatgcggat gttcaagctt ttctaagcgc acaccaagaa
    21001 gaattgacac aagcggatat tgaaaaaagt tacgctaaat tgtatgaatt cgtgcaagaa
    21061 aagcgtaaat atcaaaaaaa cgatccaacg atgatcgctc ccggctatga gccgaagctg
    21121 acgttgaatt ttcattatgt ggatgtcact tatgtaccaa cggaagcatt gttagcacgg
    21181 caaagacaag aagaaatcag aagccgagta aaagcaatgg atatgccaaa agatattcaa
    21241 tcggcttctt ttgaaaactt tgaacgtaca gatggacgag gatatgcgag cttagaagcc
    21301 ctagattttg tagagaaata tactgctgat ccaaaagggt atcataaagg actgtatcta
    21361 gtaggaagtt ttggtattgg aaaaacatat ttattaggag caacagcgag agaattagcg
    21421 attgctggat tcaccacgac gctagtccat tttccgacat ttgccgttga gatgaaacag
    21481 gcaatcggaa aagatcaagt ggcagaaaag ttagatgcag tgaaacgttc acctattttg
    21541 atgatcgatg acattggtgc agatgcgatg agtagttgga tacgagacga agtattcggt
    21601 gttatccttc aatatcggat gcaggaacag ttaccaacct tcttctcatc gaattttaca
    21661 atggatgaat tggaacagca tttgtccgtc actcaacgtg gagatgaaga gccgctaaaa
    21721 gcgaaacgga taatggaacg catacgttat ttgacaaaag aaatcgaaat gactggtcgc
    21781 aaccgacgca atggttgaac agttgacaag tccaactgac atttgaccta gtagtaaaag
    21841 caggtcagcg aatcattata tggacagaaa tgaccggaga caatcaccgc aacaagtaat
    21901 gcagaaactt aaacggagga ttttttatga gggctatttt ttctagtata tctgtagttg
    21961 gtctattttt tcttttagca ggctgcggta gcgcagatag caacacaggt tctgttgatt
    22021 cgattgatgc gggtcaaaca gtaaaaacaa gcagtacgaa aacggagaga caaagcatat
    22081 ttgtcggaac gattgaaagt atcactcaag tagaagcaga agaagaaacg cttcagttga
    22141 aactcgtcga tgtcatggcc aaagaagatc cagcgaatat gggaacgtca ttcagcaatg
    22201 acggagtgat cttaaatgct actgctgaaa aaataagcgt ggacataaat gaattgaaaa
    22261 tcggtgacaa agtccaattt acattagttg agatgccgat catgacgatg tctatcccac
    22321 cgcaagttcc tggagattcg attattgatg tttcattgaa caaataacca ataacatttt
    22381 ttcaaaaata agaaaatgtt gttttataga acgaaaaggt atatttttta aggagatatg
    22441 ggaatttttt tattcctagt ctccttattt tatttggaaa atgctataat tatctagaag
    22501 gagtgaagct atgaaccatt tagatttatc tcagcgctta gccgcagtgg gtgactttgt
    22561 ccctgaatcc gctcgtttag cagacattgg atcagatcac gcttacttac ccgttgcatt
    22621 gatattaaga ggaaaaatcg aatatgcagt tgctggtgaa gtcgttcaag gtccttatga
    22681 atcagcacgt aagcaagtca aaaaagatgg attagaagac cgtatcaccg tacgccttgc
    22741 aaatggtcta gatgctatcc agccacaaga tggtattaca gctgtcacga ttgcgggtat
    22801 gggaggttca ctgatccgag atatcctaga agctggcaag ttgaatcaac gcttaagcgg
    22861 acaagaacgt ttgatccttc agccaaacat cggagagcgt acattacgat cttggctgca
    22921 agaaaatcag tataaaatcc aatcagaaaa aatacttgaa gaaaataaaa aaatatatga
    22981 aatcattgta gccgaaaaag aacaaaaacc agttacttac aatgaaatgg agctgatgtt
    23041 cgggccattt ctgcttgaag agaaaagtga gatcttcaaa tcaaaatgga caagagagct
    23101 tcaacaaaga aaagctatcc gtgaacagct caaacaagca gctaatcaag aggcacgtca
    23161 aaaacaaatc gagcaggaaa tccaaatgat tgaggaggtt ttaaagccat gacaatcagc
    23221 ggacgcactt tcatccaaaa gtttgaaagc tattgtcctc agtggctagc tgaagaagga
    23281 gacccagtcg gactgcatat cggaacattg gataagccaa tccaacgagt aatgatgaca
    23341 ttagacgttc gtccagaagt ggtcgaagaa gcaatcaaga aaaaaatcga tttgctgatt
    23401 gctaaacatc ctccaatctt tcgtcctgta aaacggctgg ttactgatca gccacaagaa
    23461 aaaatgtatg cagatttgtt gaaacatgat attgccgtct atgcagcaca cacgaacatg
    23521 gatattattt gggatggact gaatgactgg ttttgtgaac ttctcggtat tgaagtggag
    23581 agttatttag taaagactca tgagattcat tataaaaaac tggccgttta tgtacctgtg
    23641 gatcatgcac agaaaatgcg tgaagtatta gctgcagctg gtgctggtac acaaggtgat
    23701 tataccggta caagttttac ctcgattgga cacggtcgat ttactccgga agctggtgca
    23761 caaccagcga ttgggaaagt agggaagaca gaacaagttc aagaggcaaa agttgaggtt
    23821 attttgccgg aaactatcga aaaacaagtg attcaagcca tgcggtcagc tcatccttat
    23881 gaggaacctg cttatgatct tttcgctata gatgaaccag tcgaaatgtt tgggttagga
    23941 cgagtaggtg aattgccgca agaaatttct atagaggcat ttgtagaaca agtaaaagaa
    24001 gcgttccaac tagatggact gagaatagtc cagccaaaaa atgcaaaatc ctctgtgaag
    24061 cgcattgcga tttgcggtgg aagcggtgaa aaattttatc cgcaagcaat cgcccaaaga
    24121 gcagatgtct atatcacggg agatatctat tatcatacgg ctcatgatat gcaaagcgct
    24181 gggttgattg caattgatcc cggtcattat attgaatcgt tatgcaagca acgatttatc
    24241 gagaaatttg aatcttggaa acaagaagaa aattgggata ttaacttttt cgtttctgaa
    24301 acaaatacaa acccatttca atttaattaa aaggagagaa tactatgtac gaaaatcttt
    24361 tgccacgttt tttacgatat gtcaaaacag aaacacgctc cgatgcaaca agcaaaacga
    24421 ctccatcgac tcagacacaa gttgcttttg cgcaagaatt gaaaaaagaa ttagaagagt
    24481 taggcttagc tgatgttttc tataatgaag ataacggatt cgttatggga acattaccaa
    24541 gcaatgttga tcatgaagtg cgttccattg gatttatttc ccacatggat acagcagatt
    24601 ttaatgcagt aggagtcaat ccacaaatca ttgaaaacta tgatggcgag tctacgatcg
    24661 tactagatgc ggaagaacgc tatacattga atacaaaaga ttttccaaat ttgaaaaatt
    24721 atgaaggcca cacattgatc acaacagatg gcagtacatt actgggagca gatgacaaat
    24781 cagggattgc ggaaatcatg actgcaatgg agatcttgat caataatcct tctatccctc
    24841 acggtaccat caaagtggct tttggtcctg atgaagaaat cggtgtcgga gcggataaat
    24901 tcgatgttga gcaattcgat gtagattttg cttatacagt cgatggtggt cctttaggtg
    24961 agttgcagta tgaaacgttt agtgctgctc aagcaaatat tacgatccaa gggaaaaatg
    25021 tacatccagg gacggcaaaa gatacaatga tcaatgctct acagttagca atcgattttc
    25081 ataatcagct tccagccgat gaagttccag aaaaaacgga aggatacgaa ggtttcttcc
    25141 atttgatggc attggatggg aatcctgaag aagcttctat gagttatatc attcgcgatc
    25201 atgatcgtga aaaattcgaa gcacgcaaag cacaaatcac acatatccaa gaagagttga
    25261 atcagcgatt tgatcaagaa cgaatcaaag tagatatgta tgatcaatat tacaacatga
    25321 aagaaatcat tgaaaaagat atgagcatcg tggaattagc gaaacaagca atgatcgagc
    25381 ttggtatctc tccagtgatc gaaccagttc gtggaggaac agatggttca aaaatctctt
    25441 acatgggtat tccgacgcca aatctatttg ccggaggaga aaatatgcac ggacgattcg
    25501 aatttgtttc tttacaagta atggaaaaag caacagacgt gattgtaaaa attgcagaat
    25561 tgaacacaaa gagttaaaat cgaaaaagaa cagcttatga caaggcgttc gtcccaatga
    25621 tggaatgtca tctgtctaag gctaaagggc aggacaatgg aattggttgt cccgccctct
    25681 tttttgaaga gtaaatagga ggtaaagaat ggaaaagctg ctagtttttt ataacaaaag
    25741 ttcagggaaa gatgagggtg agaaattagc acgctggttt caagattatg taaaagaaaa
    25801 gcagccagaa ttatatgtag aactagctga aactggccca tcgattgatg atgcggaatt
    25861 agtcaagaaa gcagaagcca tagaagctga tactttagta attataggtg gagacggcac
    25921 gattcatcat atcgtccaag cgttccaaaa aacattatct caataccatg tcggattact
    25981 tccaggtgga actgtcaaca accttgcacg tgttcttgag attcccctca aaaaagaaga
    26041 agctgctgac gtgatcctgg aaggcaatgt acggaaaata gactatggtc aagtcaatga
    26101 tgaagtcatt atctctacac tgacaatcgg aatcttagca gatacagcag tttggatcag
    26161 tcaagaagaa aaacagcgtt acggctcgtg gatctttatc aagaagtttt ttaagttatt
    26221 gctgaagaag aaaaaatatc atttggattt agaaacagac gaggagcatt ggaaaggaaa
    26281 atcccaactg ttgacagtca cgatgtctaa ctccgtgggc ggttttacaa attttgacga
    26341 ctcagcgacc ctagatgatg gaaaatttca tgtaacgatc gtaccttcct tagatatttt
    26401 ccgatttatt ttttatttgc ctagaatcat gagaggcaaa ttctatacga tccccggcat
    26461 tacttatttc acagccaaac gcatgaaaat ccaagcgcag gaaaaatctg tgggcactcg
    26521 aacggatgga gacacgacag atgatcttcc agttgaatta tctgttgtat caaaaggatt
    26581 aacagtttat tcaccaaaga aagaagaaaa agcttagaaa tagtagttaa cagaaagttg
    26641 gaagaagagt aatggatgta ttgttacaca atcctttgtg gttttacctt ttcattgtga
    26701 atttttactt attttgtctg atggggtatg ataaacatca ggctagaact agcggctggc
    26761 gtgttcctga gaataatttg atatttgtca gcctgttagg cggtggtttg ggaggattga
    26821 tctctcgaaa agttttccat cataaaactc ggaaaaagaa gtttactata ggattcgctg
    26881 caggtgtact tgttgatttg attctcattt attttttcca ttaaggagca ggagatgtcg
    26941 tctaaaggaa cgaaaactaa aatcattctg aatctgcttt tgctgattgt gatttttgcc
    27001 attatttatt atttaatcaa tcaatcattt gcagatatct ttgccgaatt gctgtctacc
    27061 agtgttgttg ttttggcagc ggctgttata ttagggacag tttaccaaat cgctgaaggg
    27121 cgctcaatca aagaaattgc tgaacctttc gcgccgaatt ttacaacgaa agatgggttc
    27181 ttgacctcta gctatattgc gttttaccga atcgtttcgt ttggtacagg aacgctgatc
    27241 tcggagattt atttttataa caaaaaagga atgaagctat cccagggagc aggggtgaca
    27301 gcactccata tgattatgta caaactggca gtgatcactt atgcattagc tggcttggtc
    27361 atccaattct ctctttttta ttctaatggt ccatcaatga tctggtttat catcgctggt
    27421 atccttttga cgatcgtgat tgttgccttt ttattggcga tgtccgtcag cttgaatgtt
    27481 caaatatttt ttgtcagctt atcgaataag ttatttaaaa gtgagcgttt gcggaaatgg
    27541 gtggatacat gcaatcagca gatctactct ttaagggaaa cggtccaaac cattatccaa
    27601 gacaggactg cgctattgcg gatttatcta tggaatatgt taaaacttgt attttggtat
    27661 gtacttcctt atttgattct gattgaaaac catcctaaaa tagattttct actgaccatt
    27721 tcgtttatca gctttgcagt agtgctttca ggggttattc ctacgcctgc tggtattggt
    27781 tcctttgaat ttgtctattt gttattattc agaccagttg ttggaacagt tgacgcagtt
    27841 tcttcgcttt tactgtatcg tttcagttcc tttatcttgc catttctcta tggatttgtg
    27901 tatgtgattg ctgaacggcg aagagtgatc aaagaagaaa taatagaagt aaaaaaagag
    27961 aataaagaaa atcaagggta ggtcttttat aagatctacc ctttttatca aatcaaagaa
    28021 aaacgttatg gataagataa ttttacgttt gtttggctct ttttttatat acatacaatc
    28081 aattttgttt ttttaagatt tatataagtc gagaaaaaaa gtcaaaaaac tatgtgtata
    28141 ttttgaccaa aattgaccaa agcgatataa tagtttttgt aaagatcaaa gaaataagtg
    28201 atcttacctt taattaggag ggtatacctg tatgaatatt gagaaaatga ctacgacgct
    28261 tcaagaagcg attgctgaag ctcaacagat tgcggtcact cgaaaacatc aagatatcga
    28321 cattgcccat gtatggaaaa tctttttaca atctaatcat tttggtcgaa atttctatac
    28381 ggatgccgga ttggatgtcg aatcttttga acatgaaatt gatcgtctac tggatgagta
    28441 tccagttgtt tctggtggaa acgtccaata tggacaaaac ctcagccaga atttctttcg
    28501 attattgaat gaagcagacc aaatacgtga aagcttcggc gacgagtttc tttcaacgga
    28561 agtcgttatt ttagcgttga tgaaattaaa aaattatccg ttaactgttt atttgaataa
    28621 aaacggatta tctgaaaaag aattgcgtaa aaacatcgaa gagatgagag gaggagaaag
    28681 agtgacctca caaaaccaag aagaacaata caaagcatta gaaaaatacg gcgttgattt
    28741 agtacagcaa gtcaaaagcg gaaaaatgga tccaatcatc ggtcgtgatg aagaaatccg
    28801 tgatgtcatc cgtattcttt cacgaaaaac aaaaaataat cctgttctga taggagaacc
    28861 cggtgtaggg aaaacggcaa tcgttgaagg gcttgctcaa cgtatcgtac gcaaagatgt
    28921 gcctgaaaat ttaaaagata aaacgatttt ttcattagat atgggtgcat tgatcgctgg
    28981 agcaaaattc cgtggtgaat ttgaagaaag actaaaagca gtcttgaaag aagtcaaaaa
    29041 aagtgatgga cgtatcctct tgttcatcga tgaaatccac aatatcgtag gggcaggaaa
    29101 aacagaagga agtatggatg ccggaaatct gttgaaacca atgcttgctc gcggtgaatt
    29161 acatttgatc ggtgccacaa ctttagatga gtaccgtcaa tatatggaaa aagacaaagc
    29221 gttggaacgt cgctttcaaa aggtattagt caaagaacca acagtggaag atacgatcag
    29281 tattctgcgt ggattaaaag aacgttttga gatccaccat ggtgttaaca tccatgacaa
    29341 cgcattagta gcagcagcta ctttatctga ccgttatatt actgatcggt tcttaccgga
    29401 caaagcaatc gatttgatcg atgaagccag tgcaacgatt cgggtagaaa tgaactctat
    29461 gccaacggaa ttagatcaag ttactagacg tttgatgcag ttggaaatcg aagaagctgc
    29521 actgaaaaaa gaatcagatg atgcaagtaa aaaacgcttg aaaaatttgc aagaagaatt
    29581 agctgaactt cgtgaagaag caaatgcgat gaagatgcag tgggaaacag aaaaagaaga
    29641 agtcaattct gtttcagcaa aacgtgctga aatcgataaa gcaaaacacg aattagaaga
    29701 tgcagaaaat aactatgatt tagaacgcgc tgctgtattg cgtcatggta cgatacctca
    29761 attagaaaaa gaattgaagg aattagaagc taaagcaaaa gacagcgaga ttaagatggt
    29821 tcaagagtcc gttaccgaaa atgagattgc tcaagtcgtt ggcagattaa cgggtatccc
    29881 cgtaacgaaa cttgtagaag gtgaacgaga aaaactaatt aaattgaatg aaacacttca
    29941 taaacgagtg attggtcaag atgaagcagt tgatgcggtc agtgacgcgg taattcgttc
    30001 acgggctgga ttgcaagacc caaatcgtcc tctaggttct ttccttttcc taggaccaac
    30061 tggtgtcgga aaaaccgaat tagcgaaagc gttagctgag aacttgtttg actcagaaga
    30121 tcatatggta cggatcgata tgagtgaata tatggaaaaa catgctgtgt ctcgtctagt
    30181 cggagctcct ccaggctatg taggttacga agaaggtggt caattaacgg aagctgtcag
    30241 acgaaatcct tatacaatcg tcttgttgga tgaaatcgaa aaagcgcatc ccgatgtctt
    30301 caatatcttg ttacaagtcc tagatgacgg acgcttgact gattcaaaag ggcgagtagt
    30361 agatttcaaa aatacggttc tgatcatgac cagcaatatc ggttcacagt tactgctgga
    30421 aggcgtgact gctgatggaa cgattccaga agcagtggct gaacaagtca acacgctatt
    30481 acgtggaaac ttcaaaccag aattcttgaa ccgaatcgac gacacgattt tatttacacc
    30541 attgagccta gacaacgtga aaggaatcgt tgacaaaatg gtggcgcaat tggcacaacg
    30601 tctggaacat caagaaatcc tgctgacaat cagtgatgaa gccaaaacgt ggattgctga
    30661 aaatgcttat gaaccagcat atggtgcaag accattgaaa cgatttatca ctaaggaagt
    30721 agaaacacca ctagctaaag aaatcgttgc aggacatgtt atgcctaaat caaaagtaac
    30781 gattacttta cttgatggac aacttcattt caaaacagaa gagctagaag aaatcgtcta
    30841 atcttccatt gagactataa aagaaaaaag gggtctgaca caactagtgt cagacctcct
    30901 tttttcaaat aaacagtgtt ccagaagtag tttcttcgaa aaataagccg aaatttcttg
    30961 aagctgcccg cttctgtcac aacctctttt attaggtatt tttcactttt tctaatttat
    31021 aactttcaaa gtaacgctca tcttttttac tttgagacca tgcaaacaat cccattaagg
    31081 cagcacctat cgtatttgtc agcaagtcgc ccatcgtatc catcaatgct gctcgtccga
    31141 caaacagtgt gccatcagaa gcagcaaaac gttgaagatt catgcctaag aactggtcgc
    31201 ataagaattc ccagaactcc caaaacacgc cgcaaagtcc agcaaacgca aagccgaata
    31261 agaggaacaa ccaaggactg gtttttgata tctcagcatc tttcatcaag taaccaatca
    31321 atccatagcc aagagctgtc aggaccattg gactcaccgc atgtaagatt ttgtcccaaa
    31381 aagagatgat actgatcaaa tgcatccctg tgcctaaaaa gacagagatg aacaagaaaa
    31441 accagtaaaa caaaacgatt gctgctggta ttttaagttt gaaaactttc aaaatgactt
    31501 gtggcatgaa aatcaatgca atccctaata aagattccac gataaatgtg attccttgag
    31561 aagtcgaata tttttgtgtg ataaattcat aaaaattata gcagacaacg aatacaccaa
    31621 aagcaagtaa agctatttgc acctttttga tttctttaat cactgaaagt ccctccatct
    31681 aaaaatcttt ttacttctga aagcaactca atttctgaag aaaccacttt tccgttcaat
    31741 ttgatcaaac ctattgtata taagttcagg tagtgaaatt gattttcagc tgtttcttgt
    31801 agtgcagcga tttttttcgg gtgggttccg ccttgctgtc gagtatcagt atataagccg
    31861 atcactggga tgcctttcgc ataagccaca ccgatttccg atgctacccc ggcatcgatc
    31921 gtcagcccat ctagtaaagc aatcattaaa tcactagcca acactttttc tgtgtcagca
    31981 agagcaatca ttcgactgtc tgcataagca gttttgtcat tgattgcttc attttcttga
    32041 ggaagataga tcgaaagctc agaagagagc tctctgattt ctttaactaa ctgttggtta
    32101 tataacaaat cacttttagc aaacattggt gcggcaaaat aaattttcat ctaaacatca
    32161 tcctttttat caaaaataat cgctaaagta agcttccatg tttggaatga tacgctctag
    32221 tgacttcagt gtttcttcat ctgtttctaa ccgttcgatt cttgccaaat aagaagcacg
    32281 gcgataattc atcatcaagc aagtcaatgt ttggatatcc agtcgaacgg attttcctat
    32341 aggttcattt aagacacgga cttgtccctg ttcatcccat gttaaagcga agacaccatt
    32401 attccaagga gcgacaggat cttcaatgat gaaatgaaaa gcatcagctg ttccaacaaa
    32461 cggaaaccgt tgaaggaatt cttttacatc aacgatccga gccataaaat atggttcgat
    32521 ctgctctttg atctgactat cttcaatcaa aaatgctaaa ggctcatttt tataaatatc
    32581 tccatgtacc cagtagatca tggaaaaatg tgcggaaata aagttccata agccatttcg
    32641 agcttcttga tcaagataga acatttcttt tacgtgaaat atttcttcag ctacccagta
    32701 gaacagaaca cctcttggtt catggttgct atcgtagtag acagcggctg tgcgctcatc
    32761 ttcattttcg aaacgccaat actcttccca atgaaaatca ctgcggaata aagcaccatg
    32821 gttttgttgg gcaaatttgt cataaacgga aaatacgtct ggatgatcaa ctggtaatcg
    32881 ctcaaccata ccacttactg ggatttgttt aggtagctgt gtatctctga ttttaaagga
    32941 aagtttatca gacatgattt cccatccttt acgccgatag taggggatac tgtaaggata
    33001 caaataagag atccattgct tattcttgcg catattatcc aatgcaacga taattagatc
    33061 ttgcatcaat ccatggttag catattctgg ataagttcca actccagtca caccacccat
    33121 tttataacgt gcaccgtgaa tattgacttc acaaggatag atagcgattt gagagatcag
    33181 tttattttcg tggaaccatc cgaacacttt cgatacttcc aaaatcggtt ttttggaacg
    33241 gataaaagct cgtttattct caaacccgct ttcctcgatg tctgcttcag tcacttggaa
    33301 cacataggaa agcaattcat tgaattgatc gatatgttct tgagtgaccg gttttaattc
    33361 aagattttct ctaaaatctt tttgatccat tttttcatct ccatttatta gcttgataac
    33421 agtatagcaa aattctacaa aaaaaacttc tatagctgac taattaaaaa ctctttaaat
    33481 tactgctttt cgttggtata atggaaagtg ctgattatat gaaaagagga gacgctatgg
    33541 atataaagaa aatgaaagaa cgccaagagc agattcgtaa tttttcgatc atcgctcata
    33601 tcgaccatgg gaaatctaca ttggccgatc gtattttaga aatgacgcac actgtgacgt
    33661 ctcgcgaaat gcaagatcag ctgttagact cgatggattt ggaacgtgaa cgtggaatca
    33721 cgattaaatt aaatgctgta gaactcaatt acacagcgaa aaatggagaa acatatatct
    33781 ttcacttgat tgacacccca gggcacgtcg acttcaccta tgaagtctct cgaagccttg
    33841 ctgcctgtga gggtgccgtt ttagtggtcg atgcagcaca aggaatcgaa gcacaaacat
    33901 tggccaatgt ttatttagcg ttagacaatg atttggagat cctgccagtc atcaataaaa
    33961 tcgacctacc cgcagcagat cccgaacgtg tccgtcaaga aatcgaagac gtaatcggaa
    34021 tcgatgctag tgaagctgta ttagccagtg ccaaatcagg gattgggatt gaagatattc
    34081 tcgagcagat cgtggaatat gttcctgcac caagtggaga cttagatgca ccgctaaaag
    34141 ctttgatctt tgactctatt tatgatagtt accgcggtgt tgttctaaat gtccggatca
    34201 cggacggtat ggtcaaaccc ggagacaaaa tcaaactgat gagtaatggc aaaacatttg
    34261 atgttacaga ggtcggggtc ttctcgccaa aagcagttgc tagagacttt ttgatggtcg
    34321 gtgatgtcgg ttatatcaca gcaagtatca aaactgtcca agatacacga gtaggggata
    34381 cagtaacgtt agcagacaat cctgccgctg aagctttacc aggttaccga aaaatgaatc
    34441 cgatggttta ttgtggtctt tatccaattg atacttctcg ttacaacgat ttgcgggaag
    34501 ctttagaaaa actgcaattg aatgatgctg ctttacaatt cgaaccagaa acctctcaag
    34561 cattaggttt tgggttccgc tgtggattcc tcggacttct tcatatggat gtcgtccaag
    34621 aacgcttgga acgggaattc aatctagaat tgatcacgac tgcaccatcc gttatttacc
    34681 atgttaataa aacggatggt acgactgcta cagtagataa cccggcagat tttcctgaac
    34741 ctgtaacgat tcaggatgta gaagaaccat tcgtcaaagc acagatcatg gtcccaaatg
    34801 attttgtcgg tgcagtaatg gaactttctc aacgaaaacg gggagaattc attacgatgg
    34861 attatttaga tgattaccga gtaaatgtcg tctataatat tccgctttct gaaattgtct
    34921 ttgacttttt cgacaaattg aaatcaagca cgaaaggcta tgcctcattg gattatgaaa
    34981 tgtctggtta tcaaaaaagc aagttagtga agatggacat cttgctgaat ggagaaaaag
    35041 tcgatgcatt aagctttatc gttcaccgag actttgccta tgaacgtgga aaagcaatcg
    35101 ttgaaaaact gaaaaaacta atcccacgcc aacaatttga ggtgccaatc caagcagcta
    35161 ttggacaaaa aatcgttgcc cgttcagaca tcaaagcctt gcgtaaaaac gtcttggcta
    35221 aatgttatgg tggagatgtt tctcgtaaac gtaaactctt agagaaacaa aaagaaggga
    35281 agaagcggat gaaacaaatc ggctccgtcg aagttccgca agaagccttc atggccgttc
    35341 tgaaaatgga tgagcaagat agtgtgaaat aacttataat caatcgaaaa acctattaaa
    35401 taaacctttt tgagtagatg caacactgag gattatctgt ataaaagatt ttaaactgtc
    35461 atttggttat cacggcgata ctaaaattaa caaaattgga atatttttct tgaagatttt
    35521 tagctgtcag tatatgatga aagcatctca taggaggtgc ttttttcatg gttgataatt
    35581 caagtggaag ggttcttaaa tctctaagaa aagagaaaaa actatctcaa aaaaagttag
    35641 ctgatttagc aggtatttca caaagtactt tagttaaata tgaaaaaggg tcaagaaaaa
    35701 tccctaaaga cgtagataat actctaagca agattctgaa tatagaaact ctaataaaag
    35761 atgaggaaga taagattgag attctcatcg gtaaactaat tgcatacaga gatatgaata
    35821 agttacttaa caaagagtta gctgataata taggaattag tgaagtatta ctcagttatg
    35881 tgttaaatag aaagagaaat ccgtcaaaag aaatgcaaaa aaaaatcgat atttttctat
    35941 taagtaatga aaaagaaatt ttgaaggaga ttaatcgtga tagtgagata tttagtttat
    36001 caaaagacga taaaattgtt atgggaaaaa gaatacgaga agtccgaaag aaccgggaag
    36061 agacgcttga aaaatttggt aaaaacttta ccatctatac aggcaaaaat gttataagta
    36121 gatgggaaaa aggtattaat attccagata ttgaaaaact aatgaatatt gcctatcttg
    36181 gtaaggtcac tgttccttac cttatgtacg gagaagatta taagaatata cttccaaaag
    36241 atgaaagagt tagcgatttt aaaaagataa attcttttag tatgggatta aggatgagga
    36301 aaattaggaa agattattat ctagaaaggg aggagtttgg aaagcttttt tctccttcaa
    36361 tttcaaaatg gtccatagat aggtatgaga atggtagaga tatacccaat actaatcgaa
    36421 ttatccaata tgcttatata ggaaatcttt ctttagaatt tttgatttac gggatataaa
    36481 aatagtttac gtcgatactt attaagttat cgacgttttt tattatagaa aaaatttata
    36541 aaaggaggtt tcttgatatg ataagaaaca aaaagggttt gttgaaagtt gctttactgg
    36601 cagctttttt ctaagtaact ttttgacaag ctcaatggca acacaagcgg aagaagtaat
    36661 acaagaacta actgttatga ataacagcta gataaaatgg gctatgtatg ttatccaaca
    36721 atttagtaat cactagaagc ctagcgaaag ttcgcttgat aagttataga tgagtattga
    36781 tttgtagtgt ttccaaatca aaagggtaca gagccacatg aaatatgttg tcctctgcag
    36841 cgtcaggatg ggaatccata ccatggagat tcggagatct gtgagggaat acttacgtgg
    36901 ttaatatgtc agttgtgttg gacgtagtaa tggtcatagt gggtagattg actgaattct
    36961 tatatgagaa aatgaaacca acaagaagat agggttattt atacagaatt ggggatcttt
    37021 tctggaaaag taatcggata atgcgagatt cgtacggtct tttttaaatt tctctaaaaa
    37081 aaacggcatc gaatgggttg ggtgattgat aagcaatgaa tcatagactg atatagaata
    37141 aaaaatgatt ctatttatct ttttacatct atcgtttttt caagtagccg caaattatat
    37201 cagcattcaa caatttttgt atacaagttc tagtaaaagg atctgaagaa aaagttggtt
    37261 gttgtgaaga taaaaaaaga atcaggtttt actgagtttt tcttcaaaat ttgtgttatt
    37321 aggttaggac aaagataaga agaagtatga agatttaaaa aaggaatgag gaaaagatag
    37381 taatttccga ttattggagt ttttttattt ataaagaaga agcgaataag ttgtgattcc
    37441 tagatttcgc gcgtgattaa ttaatgagca aaaaatgcgg aaagttttag tgtttaatac
    37501 acgaggacaa agtttcttag gtattgaagg cacacgtgta acggttgatg ggtggtgtga
    37561 ttgtttcgag gttggaaaac atgttgaact tatggcattt actgagctaa aagataagaa
    37621 caacgtggaa tttttcgaga gtgatattgg ttgggacgat catgaagaag tttatggaaa
    37681 atttattttg cggaagggaa attcttatac gaatggggaa gcataagtag cgatttgtta
    37741 gagatcattg ataggattga aattgtcggg aatatttatg agaatctaga gttatttgag
    37801 gtgatagaat gagtgatggt tttgaacaag tatcaataat taaaaatcaa gttcgggaga
    37861 ttcttagaaa aaaaggctat ttggtagata gttattttga aggagattac gaaacatggg
    37921 taggtgtcta tgctcgtcca gagaataaac ctacctattt agatcctacg acgtcagaag
    37981 atgcctattt acaaaatagg tatcgagtag atggttttaa gcaagacttt gcggagtggt
    38041 ttgaatggga aattgaaaac ggagaagtaa aagaagaata agagtacttg ttgtatcaaa
    38101 ataagccagt agaacaacca aaccagtagc tagtaatgac aataatactg aggaatcgga
    38161 tcattatggt atgattgata tttctcttcc agaagatctt aagccagatc ctgtaacaat
    38221 tggcaatagt gtcatgattt ttgattcatt agatgaagct atgtcatatg gttggaaaga
    38281 aattaaggat gaaggtagta attggtatgg catgagattt ggtgatggtg aagttgccaa
    38341 aaaagctggt attccaattg ggaaatggac agttgatttc cacgaagcag gttctttttt
    38401 tgttctgtaa ttatagtggg agggtaaaat cattgatgaa atgtgttcag ataagagcgc
    38461 cagataaaaa tagaagagac agttcacgtc gttatcactt ttggtaacgg cgttttgttt
    38521 tattatataa aattctcagg aaaaggagga attcttgtgt atgcaaaaac gaaaatgaat
    38581 tggttgaaag cactcgcatt ggtggctttt tctcaattct gtttcttggt gggaactgct
    38641 caagcacatg cagaagaaac gacggctata caacctacga tggaagccat tgcccaagtc
    38701 gcttctgaag tgacagaagt ccaaccagca gaagccgggg tcccagctgg tgaagccact
    38761 gttgaacagg cccctgtgac agaagcgcca acggtcaatt ccaaaacgac tctcgatcag
    38821 acgattgggg aaacacaaca cccagggaat agtcctggta cttcacaacc agttgaagaa
    38881 actgcctcaa ttacaacccc tgcttcagaa acgtccactc tagaaggaga aaaagctgcc
    38941 gaagcaacgc cttctgtgca gccagagtct tctgagaaac aagcggaaga aaagaaacga
    39001 atagaagaaa cagtggaaca accagcggct actgctgaca aagaaggaaa aaatgaggaa
    39061 aacgttgaaa aaacaatctc ttcaaccgca gctagtcaaa atcaaccaac gaaaccaaac
    39121 aaagaatcta cggctagtat tgaaaatcaa aagaaaaaag agcagaacat tccaaaaaca
    39181 ggtacaccta cactgttagt aacagtacca accaatcgtt cggttcgtgt tcgccgtgca
    39241 accaatgcag ctgttttagg tggtcggaaa attgattggg gcgaaaatat tggtgttact
    39301 tctagtccga acaatctaaa cttcacttta aattatatgg ttcgttttga gattaatgga
    39361 caagtggcgt tttgtattga gcctggtgtc tcagccgcag aaggtcaagt ttatacagct
    39421 actgctttga aaaactattt gaaaaattca aatgtacgga aaaaaacaag cttgatctct
    39481 tatttaggat atgtcacaaa taaagacaaa tccgatgaac aatacattgc ggcacaattt
    39541 atgatttggg aagctttggg cacaaaaatc ccaatcaaaa atatccgtgt tgattatgat
    39601 cgtcgaaaag cagaaattca acgtttgatt aataactttg gtgaaaaagc aacttttaat
    39661 aatcaaacac atacggtaaa aattggcgaa acgttgaaag taaagaataa aaatgatttt
    39721 ttgaaatatg tgaaagacat tcaaaaacca aaaggtgtca atgtatctat tcacggcaat
    39781 gaagtatgga ttacagtcac aaaagaggca ccggataaag caaaaattca attgaataaa
    39841 attaaagttc aaggtgcgcc attagcctat cgtcgtccag gagctcaaac aattggtgtg
    39901 ttacatccaa cagaacctaa tgcgtctgtt attaatttac aaattctaaa acaaggaaac
    39961 attcgtgtgt ttaaagaaga tgcggaaact ggtgtgaaag cacaaggtgc agcttcttta
    40021 gaaaatgcgg tctatggttt gtatcaagca gatgggaaaa agattaaaga aattaccttg
    40081 aaaaaaatta acggcaaagt acaggcagaa attaaagatc ttgatcctgg caaatatgtt
    40141 ttaaaagaaa tcaaagcgcc aaaaggttat gtgctttctg atgaagcaat tgaaattgtt
    40201 gttgaacctg gaaaaactgt caatgcgacc gcaaaagatc aagtgatcaa aggaaccatt
    40261 gatttagtga aagttgctaa taaagattta gtcgattcaa cgaatccaga taacaaacca
    40321 aaattagctg gcattgaaat cactttgacg tcaaaaacaa ctggcaaagt ggtgaaaacc
    40381 gttgtgacag acaatgatgg ttatgctact tttggtaaaa ataccgttgt ctttgatacg
    40441 tacattcttt ctgaaaccaa aggaaaagaa gggtataaac tatttgaacc acttgaagtc
    40501 acaatttctg aaaatgggca aactttccat tatgttttag aagataaagt aattgaacaa
    40561 cgtcttaaag tggtgaaagt ggatcaagaa acaggaaaag tgattccact tgctaataca
    40621 gaattcaaga tttttgatac tttagccaat cgttatgtca caatggagat tccaaatgat
    40681 acagaaacaa cggatatctt taaaaccaat gaaaaaggct ttttcctaac taacggtaca
    40741 cttacttatg gaaaagatcg ctatcgtttg gaagaaatca aagcccccgt aaattacgtt
    40801 ttgaatcaaa acccattagt gttctcgatt accaatgata cagaaccgat caaagtgatc
    40861 cattttgcga accgtcaagc acggaaaagt gtaaaattat tcaagtatga agaatggaac
    40921 aagaagaaaa cgccgctcgc aggtgtgaac tttaccttgt ataacggtaa aaatcaagca
    40981 attggtgaat ataccactga tcaaaacggg gaaattttag tgaaaggtct agttgccgat
    41041 gactattact tcttggaaaa tgccccatta gaaagtttcc aaccaaatac agataaacaa
    41101 gcattcacgg ttgcattcaa acaaaatgcg ccagatgatg gggaaacgtt agtggtttct
    41161 gtacgtaatt acttgattcc accaaaacta gaaacacaag cgtcaaataa agccgatggt
    41221 gaaaaagtgg ttgatccatt agaaacgatc gtcattaaag acagtgtttc ttataccaac
    41281 ttgtttgtcg gaaaagaata caccatttca ggagtattga tgaacaaggc aacgaatgcg
    41341 ccaattttac aagatggcaa agaaatcaca agtaccttgg cctttattgc agacaaagtc
    41401 aatggcacaa aagaccttga atttgtggtt aatgctagtg ttctgaaagg tcaaacgatc
    41461 gttgtttttg aaaaactttt ccgtgatggc attgaagttg cagcacatgc ggatatcaac
    41521 gatgaagccc aaagtgtgaa agtgaataat ccaaccgttc ataccacggc tgtctttgaa
    41581 gacggattga cagtcgcaga cccaacagga ttgtttacct taaacgatac cgttgaaatt
    41641 accgagattc ttccaggaaa agcatacttg gtcaaaggga tcttaatgga taaagcaacc
    41701 ggtgaaccct tgcttgtgca tggaaatacg gtagaaacga gtgttggctt tattgccaaa
    41761 gcagaaaatg aaacggtgat cgtaccattt acctttgatt tgacaggtat aaatggtcgt
    41821 gaaatcgtcg tgtttgaaag tctttttaga aatgatgaag aactagcaaa ccataaagac
    41881 atcaacgaca aagggcaaac ggtacgagta actaacccaa gtgtacgtac aacggctaca
    41941 cataaaccca ctggcttgaa agaggttaat ccattaacga aagtcaccat tacagacgct
    42001 gtgaaatacc acgatttggt cgttggaaaa acatacacag tcaacggtgt tctaatggac
    42061 aaagtaacgg aaaaaccagt gctagtagat ggaaaagaag tcacaagtac cttaacgttt
    42121 gtggcagaaa caacggatgg tacagtcaat ctagacttta ttctagacgc acgtgcgttg
    42181 cgaggcaaag aagtcgtggt ctttgaagat ctgtttagag aaggcgtatt attggcttct
    42241 cacgcagata ttaccgacaa tgaccaaacc atcaaaatca gtaatccaac cattacgacg
    42301 aaagcgacga ataaaaatgg cggaaaagag atcttggcct tgccaaatca aactgtgctt
    42361 gaatgggtca aagtagacgg tcttgcgatt ggtcaaatct atcgcttaat tgttcaaggc
    42421 tacttaacac cagacggcac accatttgaa ggcactcatg cggaaaaagt ctttgcggcc
    42481 gataaagaaa tgatggaatt cttatttgaa ttcttagtgg acggtcgcaa tcttgcagga
    42541 aaaggcttga gttttgcgga atggctccaa gcgaaaacgg aagatgagaa agaaacgttt
    42601 gaagaagtgg cgaaacacaa tgtagatcta acaaacaaag atcaaacggt tcaaattgtg
    42661 gaagcgccaa aaccaccgca accagtgaaa ccagaacaac gggttaaacc agctactgtt
    42721 gtaccaatgt tgccaaaaac aggtgaacaa acaagtagta tacttatggt tcttggatta
    42781 gtagtattag tcattgcttt aggtataaca ctttataaag tacgtaaagc caaagattag
    42841 tcatgaggaa caagcggtta ggatttttaa ccgcttgttt gattgtaatg tagaaatatt
    42901 tagaatttat tttggttttt aagaggagga aaaactttat ggcagaaaaa gcattgcgta
    42961 tgaagaaaga gtttttaggt caagtatttt tattgggttc acgggaacct aatccaccaa
    43021 aggaaattaa tggtgtgtct gggcgatatg ttcaattaca agcagagtgt tcgcgagaag
    43081 aacagcctgc tttttttgtt tatctcacag ctgaagagga taaaagatta cgattaccag
    43141 aaaaagaggt gcgtatttca tttgaagaag cttattttgt ttttcgtaaa gaacgagtga
    43201 atagtcgtga aacaaatgat atgggacaaa cagagcgtcg aacaactggc tatcaagatg
    43261 ttggtgtctt tttaactggt gtaaaaattg gggaggtttt gtaagatggg attaaaattt
    43321 ccaaataatt atgacattac agaagcatta gatgaaactt gtttaggagc cgtacgcttt
    43381 ggcgcattag aagagtctga tcgtgtattt gataatgaaa caggcgatta tacgggagaa
    43441 attcgatcac agcgagcaca attagttttt ggaaatccag atgaaccaaa gattgcacga
    43501 cgagttaaat ttccagcaga tgtagatttg actggtttta aacgacgtga tcctgtgaaa
    43561 ttaattgatc cagaatatca tgtggtatat attccagcac aagatggcaa tcgtgaatat
    43621 tcagatttag tgatttatgc gaaaggatta gagaaagtag aagctccaac aaataatcct
    43681 aatatgaaac aatcacaaga aaaaggttta gatcaaaaac aaccaagtgt tgattctaag
    43741 gaaaaagaga aaaaataagg tttttttgaa agaataggaa ggagtcttcc tattcttttt
    43801 atctaagata gaaggaaggg gagattttga attcagataa aaccaatcaa atactttgag
    43861 agattgtgct tgttatcaaa atatccaaca attgattgag tattttggag acaatccaac
    43921 gatttttgta caaacaaatg catatatttg tgcggttatt gggcagtgta tgtttttacg
    43981 tgatcttgtt cgtttttcat taccgtacca gtggaaacaa gatcatcagg aagtgatttg
    44041 gattcgtata gtacgaatat gtaatatgtg tgcacaccct tataaaaatc gattaaatct
    44101 ttttcgatta tgttttttta ctaaatgtga tattcctgta ttagttgctt tttgtcaaaa
    44161 gtttttagca caggaaaagt aaaaacagaa aggaggaatg tgacaattga aagctcattt
    44221 tttcaagtat cgtggtcggc gaattcgcta tttcaatcgt tatttatggt tttgctatta
    44281 tggtttcttt ttgtttccat ttttgattct gttaggttgg tttagttgga aagtatttta
    44341 tccacgttta agtacgtttt cgaattggca aatgtatctt attcctggaa taagtattgt
    44401 gttgtatttg ttgctggtta gtgggttaat tttagggttg atgcattggt cgcgactaaa
    44461 agaaggatat tttgcctctg tttattggcg tcagttactt gttcgaatgt taattgacaa
    44521 tcggtttgtt tatacaaaga aacaagttag tgagaaacaa acaagggaaa aaatgagatt
    44581 accaaaagtt tatttttatc aaaagaaaca agaattagtg gtttcttttc ctttagatgg
    44641 tgggcgtttt cacgaacgat ttttaaaaat gggtcatttg ttatctgaag tatttttgcg
    44701 tgatttaatt cgtgaagaac gagaaaaagc ccgaatcaat tatgtattcc tttcagattc
    44761 tggtcggatt cctattgatc aatgtatagc agaaaatgga cgtattcatt taatgaaaac
    44821 tttggattgg gtatatgatc aatcaccaaa tatgttgatt gctggtgcaa tcggtggtgg
    44881 gaaaacctat ttattgtatt ctttaattca agcttgttta agtgttggga cagtagatat
    44941 ttgcgatgga aaagcggcag atttagcagc attaggtgac gtcgatgtat tcaaaggaca
    45001 tgtgttttac aaaataaatg aagaaatgat tatttgttta cgaaatgcat taaaagaaat
    45061 gaatcaacgg tatgcctata tgaaaaccat gaaagatcct aaatatgaac cagggaaaaa
    45121 ttatgcttat tatgggttac caccgcattt tatctttttt gatgaatggg cagcttttta
    45181 tggttcgttg gatatggaag cgagaaatag agtcgataaa ttgattcagc cattagtatt
    45241 aaagggtcgt caagcaggga tgtacattat tttagcaatg caacgaccag atgcagaata
    45301 ttttccaagt ggtgttcggg ataatttaac attccgtatt tctgttggtc gattgtctcc
    45361 cattggttat ttaatgactt ttggagaaga ttttaaaaat aagccatttt acaacaaaga
    45421 tcaacctggt cgtggatatg cttttccagg atttgatgta cctgtagagt tttttgcgcc
    45481 atttgtttac aaagattatc actttatcaa agaatttgag aaatttactg aaatgattgt
    45541 ctatgatttt acagtaaaag aggatagtca agatcaaacg atgggagatg ataatcagtt
    45601 gttacaagaa caactagagc gccaaatgta tttagcaaaa gatccaaaag gaacaagttt
    45661 ttctgatgcg catattttgt aatcaactaa ggaggtgaag ttaaatggca gagagttgtt
    45721 attatagagt agctacagca atacgaatga ttaatccttc tctttcttcc agaacgtttt
    45781 atgattggtt gaatcgtatt gaacaagtaa ctgattaccg ctttttgcgc aaagaacgtg
    45841 tttttacagg aaaagttatt aatcaagtat tgctaacgaa aaaagatata gaacgattga
    45901 ctcgattgta tcattatcga gtagatttag aagaggattt aactttgtca atttatcgcg
    45961 ttttttctcc tgaaaaatat agtgaaataa caaaattaga tcatttaatt ttgtagttat
    46021 tatctatcgg gagggctcta gacgtagtct ggtagccgca ctctgcctgg cggtgcgcat
    46081 taaggctgcg aagcatgggc ctataatgcg cactcgctag cagcgtgtgc agctcacaaa
    46141 gaggtcgtgc gcttgcgcac ggcctctttg tgtaaagccc cccgatatat aatatggggg
    46201 gcagaaataa cataacacat agaaaaaagt tttataaacc cttttgtatc aagtgattat
    46261 ctaaggtcag cagttgtact acttttccca aaaaacgagg gggactagtt gatatatcgg
    46321 tgtttctaaa gggttaaaaa aaatcgattt tgttatttta taaaaggagc gagaaaatga
    46381 caccgattga gctaaaaagc tacagaaaga agttaagtgc aattcataat ataagtggag
    46441 ataaaaagcc gctatcacaa gcaagatttg cgcaattgat gggctgctca aaagattaca
    46501 ttagaaagat ggaacaaggg aaaagaaaaa tcccagagga ttttgaacaa cgaatcaagg
    46561 aacgctttcg attgtatatg aaaagcggaa tagatcttcg agcaatgatt gattatttgc
    46621 gtctttcctt ttttgggaca gactacaaaa cagtgattca acgtgtatta cgaatggatc
    46681 tgacagaatt tgaaacacgt ccaacgggct tgtatctttt tgactgtctt tctgttcgtg
    46741 ggaatatctg ggtgttctgg cattcaaaac gaactgtaac agaaaatgta cttgtgcaat
    46801 tttcaggaca aggttgccgg gaatatgagg aagtcatgcg tgaacaacaa acagattggc
    46861 gaacatggct atattccatt tggaaaaatc aaggaaagtt ggaagctggt tatacacgtg
    46921 tgcaatgtag ccgattcgat attgcgttag atgaactttg gggattggaa acggaagaac
    46981 atttcgatct ctttgaatta ctagaaaaac aaaaagcagg tttattagaa atggacttta
    47041 agagattcca gaatattggc ggttgttttt tagatgatgg ctattttcga agtgaaggat
    47101 tatctttgta ttttggatcg cgaaagagtc ctctcttttt taatttttat gagaaacgtt
    47161 ttgaaattgc gaaccgagaa aaaatttcag aattagaagc attaacgaaa tatggtattt
    47221 ataatcgata tgagttacgg ttagccaatg agaaagcaac acaagcagta gaagcattta
    47281 ttttaggtga ttcaccgaaa cgtttaggag agattggcgt tggtttaatt aatgcaaaac
    47341 ttattgtttg ggatagactg gaaagtgatg cacggattgt tgataaacga tgggcaaaat
    47401 tatttcgttc gatggaagaa ttggatttta cagtaaagcc agaaaaattc tcattagatc
    47461 gttcagaacg ctggtttttg aaacaagtag ctccgacatt aaagttgtta caagaagcag
    47521 atcgtatttt aggaagagac tttgtacaag aagggattga taatgccgaa ctaaatgacg
    47581 agcaacaaaa ctatctagaa tggatgggaa cgtcaggagg gaaaattgca tgaatgcata
    47641 tacgacaaca gaatggctgc gcctgttgga tttaaaggct gcaatcgaag cattaaatga
    47701 aaagatggtt gatttgtctt attttcgttt tcgagttcct tatattgaac aagcggtaaa
    47761 agctggacgt tatcaggaaa aagagaactg gcaagaaatt gcacgcttat tagaagttcg
    47821 taagggatac gaacaagaac tcgaagagtt ggaatttagc cgaaggaaag gaaggctaga
    47881 attcattcgc ttttatcgat tttcattgcc aatacctgcg attttagcgg ttaaaaaagg
    47941 ctgcgataaa atgaagatat atgaaaactg tgtggcagca cttagcagcg aaaaacctct
    48001 tatggaagaa atttcattgg tgactgtcac ttgggaaatg agtcgccagc caacagaaga
    48061 acagacatat ctttctttag aagagattga gatagaatta gaggaaattg gtcgctatgc
    48121 cacttgttct acctattgtg gatcggtcat tagtattgct ggtgtgattg tctaaatgaa
    48181 aaaaattatg atttatgttg gtgcgtattg gtcacgtgat ccaacagtat tagaaaatcc
    48241 agaggcggta cactattgct tgcgccaatt attctatctg tataaagaac gattagaatc
    48301 gttgattcgt cagttaccat atactgacag acgtttagat gaacttcttc taaggtatcc
    48361 agcaatgtat aaacgacgaa aaaatagatt gttaccagaa gagtatccca ttgaaaaaca
    48421 tgaacttgaa gggcgatttg tggcttattt ctatgatgat gttcgtatgc gcttagtaga
    48481 acaacgaatg gaaatagaaa atgatcgcta ctattttatc aattattgta agaagcgtaa
    48541 gtatcaagta actgatgatt tttatgattg tattttacaa gatggggaag tgattctatc
    48601 caaaattgct ccaagttttc gtgaacttgt gccgattgat tttttgaaaa aatgtcattt
    48661 gcggattctt ccgtaaaaaa gagctataaa aggaaagaaa agtagaagcc aaatcggttt
    48721 ctgctttttt atttttttta ggaaggagaa gatggtatgt cactggaatt tttaggagag
    48781 ccaattgaaa aggaagagtt cgtttcgcat tatatggatt tgtttattca ggtgataaaa
    48841 aactttgtgc gattgatgaa ttttatccac gcgaacaaga ctatctagcc gctgaacgaa
    48901 taaaaatcag tttattatgg gaaaaattca cagatgaaaa taaccgaccg ccagattatc
    48961 gctatttatc agattgttta acgaataatg tgctttctaa agaataccta tttcacaaac
    49021 gtgagaaaaa tcaaatgtcg gttgaacatt tttgtgattg ttatattgca ttattgcgta
    49081 gtcaacagtt attaacagta gaacgatatg gtgcagagtt tggttatgtc atgcaagctg
    49141 agcgtcatag agctacaaga tgctatgaaa aagaagatca agtgattgat ggctatgaag
    49201 aattatgtat tcgaaacaat cgctatttgc aacaacgttt atatgaacaa ttgatgatgg
    49261 atttttcaaa tctctataga gggtatgaat gttcgatgat tcaagaaagg tagaagaaaa
    49321 gggggaattt ttatgtggcg attattattt ttggtggtat gtggtatggc attgttctat
    49381 gtgtatcgtg tctatctcta tccacgaatg gaacgatgga caagttggta tagagatcct
    49441 ttaaaacaac gaaaaggatt gaagcggtat cgttatgaat tacttgttga attttcggat
    49501 gggcgacaag cacagtatta tttttttgca aactatccaa aatacaacac cagtgaacta
    49561 ttgattcaat tattcaaaaa taatccatat gttgggttag aagaaaacgg acgggagttc
    49621 ttttatcgtt cagataatat tagtgcggcg tctatgaaca aaacacgaat tgcataaaaa
    49681 attggaggaa taatcatgaa aaaaacaaca ttagcagtcg taacaacact aggaatttca
    49741 ttattttcgt ttcaattagg gagttcattg gtttatgcag atgaaactgt agaaacacct
    49801 aagtcagaaa ttgtagaaac attgccaggg gaaggattac cagatgttga gacagagcta
    49861 aatggaggaa caacggaaaa accagcagaa cctgaacaat tgcagtcaga gaaacctgaa
    49921 aaagagccag tgacaccaga accagagttt cctgaatcaa ctttaccgac tgattcgatc
    49981 gaagaagaag gtgtgcatag ttcaacaaca acggattcaa gtatagtcac aactccggaa
    50041 caatcaggaa caaccagttc ttctgaaaag aatactgatt cgtcaagtac ggaacagcca
    50101 acgatgtcgt ctaccagtga agaacaaaaa gaagaaccga aacaacctgt tgaaaaatca
    50161 gaagcaattc caaaagaaaa taaacctatt gttccagcaa aagaagtcac agtatcggta
    50221 accccaagcg gtgaaattac gacgaatact tctcaaggaa tgagtgtacc gattgtcact
    50281 agtaatgtag aggaattgac ccatattcca acaccaacca ccccattaaa agtagcaggt
    50341 gatcaaacaa ttgttggtgt aaaagatggt attccattaa tccaagatag tgaagggaat
    50401 ttggtaaagg atttgtcgat tcctgtaaag aaacttccaa gtggcaatat tgaaatcaaa
    50461 acagcagatg gaaaaacaaa agtcttacca aagactggtg aagaaataca tgttgcactt
    50521 tctgttctag gaggagtgtt gacaagtatt gctggatttg ttggatataa aagaaagaga
    50581 aaaggaatag aaaatgaggg taattgaatg gactattttt cagaaaaaca agcttatcgt
    50641 tgtcaatcgt acgtactagt aaaaacatac tagaaggagt agcttatgaa aaaacgacaa
    50701 ctacggcgga aagaaaaagt ttatacagag aaagtaccga agcaaaagaa aatccattca
    50761 aaaaaagcag tgaaatggat ttggtgtttg gttttatttc tttgtttttc agggggcttg
    50821 gcattttttc aatccatgaa aacgaaggtt caagtgtcgt ttttgaaaga tgaaatccaa
    50881 caattacaaa agaaagaagt acaaagtcgg tcagaattaa cgtacacacc tgaaattgaa
    50941 tcctttatga atcgttttgt tgctttgtat atgaatacat tcgataatca tgaacaagaa
    51001 caacaacgtc aagaaacatt aaaaaaagag ttttatgcac aaaactttat tcaagaacca
    51061 ggaagtgttt caggtgttcg aaaattaact gctgcttcgt ttattggatt aaaagaaatt
    51121 gaaaccattc caactgctag ttataaagta acttatgata ttcgctcgat gaatccagag
    51181 agtaagaaag aaacaagtgt gacaatcaca caagtactca atcttccctt ttctatttca
    51241 aacaagggct gtcgtattat tgcttatcct tattttacgg cactaccaaa gaatacagaa
    51301 aaacaacgaa tgattactta tgatgacaca ttatacgaaa cggttgatgc gtcggaagcg
    51361 aaagatgttg aaggatttgt ggaagatttc ttagataagt atgcgaaaaa caatgcaaaa
    51421 gatatgtcat acatgatgaa agaacctgaa ggactcaatc aaacagctaa agttgatcaa
    51481 gtagagatga aagtattgcg ttataaagaa acgaaaaaac cttttattgt aaaagcaacg
    51541 gtcgtctttc gagatggtga tacgtcactt ttacaaaaag aacaaatgac gattgtcatt
    51601 acga
//
LOCUS       DAZKCW010000016        51261 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000016 DAZKCW010000000
VERSION     DAZKCW010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.016"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            290..1135
                     /locus_tag="ACG84Z_001002"
     CDS             290..1135
                     /locus_tag="ACG84Z_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9161860.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="ACG84Z_001003"
     CDS             1416..2636
                     /locus_tag="ACG84Z_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFP9161861.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="ACG84Z_001004"
     CDS             2633..5353
                     /locus_tag="ACG84Z_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9161862.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="ACG84Z_001005"
     CDS             5337..6281
                     /locus_tag="ACG84Z_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFP9161863.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6350..7360)
                     /locus_tag="ACG84Z_001006"
     CDS             complement(6350..7360)
                     /locus_tag="ACG84Z_001006"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9161864.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7540..7884)
                     /locus_tag="ACG84Z_001007"
     CDS             complement(7540..7884)
                     /locus_tag="ACG84Z_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFP9161865.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7877..8311)
                     /locus_tag="ACG84Z_001008"
     CDS             complement(7877..8311)
                     /locus_tag="ACG84Z_001008"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFP9161866.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8449..9186
                     /locus_tag="ACG84Z_001009"
     CDS             8449..9186
                     /locus_tag="ACG84Z_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161867.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9179..10390
                     /locus_tag="ACG84Z_001010"
     CDS             9179..10390
                     /locus_tag="ACG84Z_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9161868.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10594..11376
                     /locus_tag="ACG84Z_001011"
     CDS             10594..11376
                     /locus_tag="ACG84Z_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFP9161869.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11446..12108
                     /gene="trmB"
                     /locus_tag="ACG84Z_001012"
     CDS             11446..12108
                     /gene="trmB"
                     /locus_tag="ACG84Z_001012"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFP9161870.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12206..13960)
                     /gene="ade"
                     /locus_tag="ACG84Z_001013"
     CDS             complement(12206..13960)
                     /gene="ade"
                     /locus_tag="ACG84Z_001013"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFP9161871.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14092..15021
                     /gene="comGA"
                     /locus_tag="ACG84Z_001014"
     CDS             14092..15021
                     /gene="comGA"
                     /locus_tag="ACG84Z_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFP9161872.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14978..16027
                     /gene="comGB"
                     /locus_tag="ACG84Z_001015"
     CDS             14978..16027
                     /gene="comGB"
                     /locus_tag="ACG84Z_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFP9161873.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16024..16302
                     /gene="comGC"
                     /locus_tag="ACG84Z_001016"
     CDS             16024..16302
                     /gene="comGC"
                     /locus_tag="ACG84Z_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFP9161874.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16277..16747
                     /gene="comGD"
                     /locus_tag="ACG84Z_001017"
     CDS             16277..16747
                     /gene="comGD"
                     /locus_tag="ACG84Z_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFP9161875.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16719..17066
                     /locus_tag="ACG84Z_001018"
     CDS             16719..17066
                     /locus_tag="ACG84Z_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161876.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            17029..17454
                     /gene="comGF"
                     /locus_tag="ACG84Z_001019"
     CDS             17029..17454
                     /gene="comGF"
                     /locus_tag="ACG84Z_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFP9161877.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17426..17785
                     /gene="comGG"
                     /locus_tag="ACG84Z_001020"
     CDS             17426..17785
                     /gene="comGG"
                     /locus_tag="ACG84Z_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFP9161878.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17957..18964
                     /locus_tag="ACG84Z_001021"
     CDS             17957..18964
                     /locus_tag="ACG84Z_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9161879.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18989..20173
                     /locus_tag="ACG84Z_001022"
     CDS             18989..20173
                     /locus_tag="ACG84Z_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFP9161880.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20610..22193)
                     /gene="abc-f"
                     /locus_tag="ACG84Z_001023"
     CDS             complement(20610..22193)
                     /gene="abc-f"
                     /locus_tag="ACG84Z_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFP9161881.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22298..22426)
                     /locus_tag="ACG84Z_001024"
     CDS             complement(22298..22426)
                     /locus_tag="ACG84Z_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161882.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22771..22914)
                     /locus_tag="ACG84Z_001025"
     CDS             complement(22771..22914)
                     /locus_tag="ACG84Z_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFP9161883.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23136..23615)
                     /locus_tag="ACG84Z_001026"
     CDS             complement(23136..23615)
                     /locus_tag="ACG84Z_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFP9161884.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23688..23972)
                     /locus_tag="ACG84Z_001027"
     CDS             complement(23688..23972)
                     /locus_tag="ACG84Z_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161885.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24050..24244)
                     /gene="ssrS"
                     /locus_tag="ACG84Z_001028"
     ncRNA           complement(24050..24244)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACG84Z_001028"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24316..25602)
                     /locus_tag="ACG84Z_001029"
     CDS             complement(24316..25602)
                     /locus_tag="ACG84Z_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFP9161886.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25740..26411
                     /locus_tag="ACG84Z_001030"
     CDS             25740..26411
                     /locus_tag="ACG84Z_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFP9161887.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26377..26865
                     /locus_tag="ACG84Z_001031"
     CDS             26377..26865
                     /locus_tag="ACG84Z_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFP9161888.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26878..27825
                     /gene="prmA"
                     /locus_tag="ACG84Z_001032"
     CDS             26878..27825
                     /gene="prmA"
                     /locus_tag="ACG84Z_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFP9161889.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27826..28590
                     /locus_tag="ACG84Z_001033"
     CDS             27826..28590
                     /locus_tag="ACG84Z_001033"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFP9161890.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28823..31036
                     /locus_tag="ACG84Z_001034"
     CDS             28823..31036
                     /locus_tag="ACG84Z_001034"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFP9161891.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31047..31493
                     /gene="dtd"
                     /locus_tag="ACG84Z_001035"
     CDS             31047..31493
                     /gene="dtd"
                     /locus_tag="ACG84Z_001035"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFP9161892.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31664..32923
                     /locus_tag="ACG84Z_001036"
     CDS             31664..32923
                     /locus_tag="ACG84Z_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFP9161893.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33012..33959)
                     /locus_tag="ACG84Z_001037"
     CDS             complement(33012..33959)
                     /locus_tag="ACG84Z_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFP9161894.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34353..35645
                     /gene="hisS"
                     /locus_tag="ACG84Z_001038"
     CDS             34353..35645
                     /gene="hisS"
                     /locus_tag="ACG84Z_001038"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFP9161895.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35660..37429
                     /gene="aspS"
                     /locus_tag="ACG84Z_001039"
     CDS             35660..37429
                     /gene="aspS"
                     /locus_tag="ACG84Z_001039"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFP9161896.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37538..38413
                     /locus_tag="ACG84Z_001040"
     CDS             37538..38413
                     /locus_tag="ACG84Z_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9161897.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38679..40562
                     /locus_tag="ACG84Z_001041"
     CDS             38679..40562
                     /locus_tag="ACG84Z_001041"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFP9161898.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40637..40921)
                     /locus_tag="ACG84Z_001042"
     CDS             complement(40637..40921)
                     /locus_tag="ACG84Z_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFP9161899.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40911..41645)
                     /locus_tag="ACG84Z_001043"
     CDS             complement(40911..41645)
                     /locus_tag="ACG84Z_001043"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFP9161900.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41774..42397
                     /locus_tag="ACG84Z_001044"
     CDS             41774..42397
                     /locus_tag="ACG84Z_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFP9161901.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42589..43710
                     /locus_tag="ACG84Z_001045"
     CDS             42589..43710
                     /locus_tag="ACG84Z_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFP9161902.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43717..46845
                     /locus_tag="ACG84Z_001046"
     CDS             43717..46845
                     /locus_tag="ACG84Z_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9161903.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLNLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46864..50058
                     /locus_tag="ACG84Z_001047"
     CDS             46864..50058
                     /locus_tag="ACG84Z_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFP9161904.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFHQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50204..50911)
                     /locus_tag="ACG84Z_001048"
     CDS             complement(50204..50911)
                     /locus_tag="ACG84Z_001048"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9161905.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16779 a         8949 c        10634 g        14899 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 ttgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttcttt tattttgatg
     6361 aatcagttgt ttcttcagtt gaagattctt ttgttgaatc agttgatttt gtgtcagaac
     6421 tctttgttga agctgtagtt tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg
     6481 cactcaacac attttcaaag gcatcatctt tgatttttac atttgcatct tttaattctt
     6541 caccgattac tttagttgtg aatgcattgt cacttagttt agtttcagta gcgatatctt
     6601 ttagttgatc tttgtattta tccatgtcat tgcctttatt ttggtttttc accattttga
     6661 caacgtagta ttctgtcgca taagaagtag gatttgttgt agtaataaca tcggagatct
     6721 caccgtcttt caatttgaaa gctgcttctt ttacttctgc aggaatagtt gttgtcgttg
     6781 agtcgaattt aactttaccg ccatcttctt ttgtctctgt atcagttgat ttgtctttgg
     6841 ctaatttaga gaaatcatct ccatcatccg ctgatttttt cacatctttt gcttcatctt
     6901 cacttgataa tttgatgatt tgtgcttcta cttctggatg gaaagatttc caagcagttt
     6961 tcaaatcgtc atctgtaata tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt
     7021 tacgaatata ttctttataa gtatctttcg tatatccagc agcttctaat tgtgattcaa
     7081 aagtatcacc taatgatttc gcttgtttgt cgtattctgc atccacttgc ttatcggtta
     7141 ctttatcgcc atatttgtta ttgaatactt tataaatgat catccgttgt actaaggatt
     7201 ggttcgatga ttcaagtttt gcttcatcat agaaatcaga tacagtgatc gttccgcctt
     7261 tcatcgttgc gatatcttta ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca
     7321 acgcactagt agctgccaaa ataattgatt tttttttcat taaaatttgc actcctgtaa
     7381 ttagttatta tttttatata ttaactatac catatcccat ttcctttaaa aacgttgtcg
     7441 tggtagtttc aaacaaaatt caaaatttca tcacattcct aggaaatacg caaacttttc
     7501 tcacttatat agttaaatct gttgagaaaa taatcattat tatatttgtt caggatactc
     7561 tggcagatca gcttttagtt tttctacttg ttcattgatt tgtgtgatac gtggttcggc
     7621 ttggaattta aaatcttcga tatctttttt gattgcttct tggaaagcag gaatcacaga
     7681 ttcagctgtt tcttttgttt cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa
     7741 atcatttgtc agagttgttg cttcttccaa ttcttcgatc agtttctttc ttgtttcatt
     7801 cccgctcctg ggcgccaata acagacctcc gacagtgcca gcagcagctc caaataacag
     7861 tcctttgaaa aagtttttaa tcatcgcagg acacctgctt tacgattgtt tcttgaatag
     7921 cttttagttc ttccgatcca taactatctt gatgattgac aaagtgaata gaaaaatcat
     7981 cctctttgct gtagcgaggg actaaatgga tatgtgaatg aaaaacagat tgataggcta
     8041 gttcacggtt gttattcaag atattaagac ctttcatttc tggaaaagct ttttccaatg
     8101 cttgagcaat cttaggcaca cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa
     8161 aaatatctgc tacatgacgt ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga
     8221 tgtctaaaaa agcatagacc ttgtcgtctt catatatttt atagcttggg atttcttgat
     8281 tgatgatttt gcaaaaaata cagttttcca tataaaacat cctttctata aagaataaat
     8341 acttcagctt aactttacca taagttaaag ctattgtaag gaaaaaaaca aaataccgtc
     8401 attttcttcg tggtataata aataaaaata aatggcggag gaaaaagaat gagtttaatt
     8461 atcgatcatg tcacaggggg gtacggacat ctccctgtgt taaaagatat cagtttcgat
     8521 gtacagcctg gagagatagt agggttgatt ggactgaacg gagcagggaa aagtacgacc
     8581 atcaagcaca ttatcggtct gctggaagct tcaaaaggaa cgatagaaat caatcatcta
     8641 tccttaaaga aaaatacgga agaatatcgc aaacaaattg ggtatattcc agagactcct
     8701 tctttatatg aagaattgac attgagagaa catatcgaag tcactgcgat ggcctacgat
     8761 atacctatgg atatagcaat gaaaagagca gaaaagttgt tggagacttt tcggttatct
     8821 aatcgtcttg actggttccc agctaatttt tcaaagggaa tgaaacagaa agtgatgatc
     8881 ttatgcgcct ttttgatcga gccttcttta tatatcatcg acgaaccatt tttaggcttg
     8941 gatccactag ctatcaatgc attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc
     9001 ggtattttga tgtctacgca tattttagct actgcagaaa aatattgtga tcgttttgtg
     9061 gtcttacata acggagagat acgagcagac ggttctcttg agatgttgag aaaagaattt
     9121 cagctgccgg attcttcttt ggacgaaatc tatattgctt taacaaagga gcaggcacat
     9181 gagtagtttt tttcaaaaac gtttagcaag acatcaaaag aaaatgatga aatatatgcg
     9241 ttatgtattg aacgatcatt ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt
     9301 atattattct aattggttga aaaccctgca gccaccgttt gcaattggag ggctcataat
     9361 ctctgtattt tggatgctct gtttattcgt gggtaagatg gctacttttg cagaggcagc
     9421 agatattgtt tttttacttc ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt
     9481 tcgctattct tgcatttttc cgttgatctt tttgatattg gcatgcggat tggccatgcc
     9541 attagtggtg gttagtacgg agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt
     9601 atggagtttg aaattcagtc atctgcaaat caagagagca gaattgtttc gactagatca
     9661 acaagttatt cgttattgga aattaggctg gtttttttct tctctgatct ttttgtttct
     9721 atcattttat tggctaatat gggcaggaat agcaggtgca ttagtacagg caagtctata
     9781 ttactggttt ttgtggaagc aacaagaaaa aggattggat tgggagaaaa tggtgcatgt
     9841 agaagaacat aggttgcatc agatctatca atttatcaat ttattcacag atgttcctga
     9901 aattacggca aagatcaaaa gaagacgcta tttggatcct atattgactc atattaaaag
     9961 agaatcaaaa aacacttatc tttacttgtt tgcaagaaga ttggcaagag gttctgattt
    10021 tagtggtctt tatttccgat tagtaattat aggtgggtta ttgattgccg gagtagtcga
    10081 cttttatttt agtctgatta tcggtttctt atttttatat ttgatcggtt tccaactgtt
    10141 acctttagcg aaccagttcc gctatatggt tctcgttcag ctttatccaa tccataagaa
    10201 tcagaagaag caggcgattc agtatctact cacatgggta ttaattatcg cgtcggttat
    10261 ttttggtttg attgctgcag tcgtattaga tgggcagcag cgatgggttc cgctagcggc
    10321 ttatttgatt gttactatgc tctttgttaa actatatgta ccaactcgtt tgaagaagat
    10381 gtcagactga aaacaaagct gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca
    10441 gtaagaatgc tgttcgttct attttttttg agaaaagctg gttttttgaa tggcaattaa
    10501 atgaaaaaga acgtatatgt gcttgacgtg tagtgttcag gcgactagaa taataagtac
    10561 tgcaaaacaa agagtaagag gacgggagaa tgcatgatgg agtttcagtt agaccaagag
    10621 tggcggttac gtcccatcaa aggcgacaca ggaaaaacat acataggcat gcgtgatgag
    10681 gacaaagtct ttattaaacg aaacacgact ccgatgttgg ctgctctttc aagggaagga
    10741 attacaccaa aacttgtttg gacaaaacga acggggaatg gcgatacttt gacagcacaa
    10801 gagtggctgg aaggtcgctt gctgactcct aatgagattg gtcaaagaaa cgacgtgatt
    10861 gatgttttgt accatttaca tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt
    10921 ggtcgtgtca tgacgccgga gaagatgctg caaaaatatg aaaaagaatt accggaagaa
    10981 ctccagaaaa atcaatttct gcaaattgtc catcgttttc ttcgtgagca gatcccgtca
    11041 atagataagg aaaacttatc agtagtacac ggagatgtaa accatcgtaa ttggttagta
    11101 tgtaaaaatt atttatatct agtcgattgg gattcaatca tgtttgcaga ccctgcggtg
    11161 gatattgcaa cgattttagg aaattatgtg ccactgtcta gctggaatca gtggctgatc
    11221 agttatggca tacgcccgac tgacgaaatg cttgaaaaat ttcattggta tgcggccatg
    11281 aatttgctcc aagaaatcac cagatattgc aaacgtgaag atcatcgacg gatgaacgaa
    11341 gaaattttac aattaaaacg aattttcagt ggctgaggtt tggcccaaac tctgcggaga
    11401 tttggccaga cctttttaat tagaggaaag gaatggagat aaataatgcg tgtccgaaat
    11461 cgtccgggag cagcggaaat gttagcggct cacccgaatt ttgtaattag tgatccaaca
    11521 ttgtggaagg gaaaatggaa tgaattgttt gaaaacgatc atccaatcca cattgagatt
    11581 ggtatgggga aaggccagtt catcactgga atggcaaaag cccatcctga aatcaattat
    11641 attggagtag aaatgcaggt cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa
    11701 ccgcttccta acctgaaact tctacatgtg gatggatcag cgttgacaga gtatttcgct
    11761 gacagcgaag tagatcaaat ctatctgaat ttttccgatc catggccaaa aaaacgtcat
    11821 gaaaaacggc gattgacata taagactttt cttgctgtag atgaacagat tcttcgtcca
    11881 aatggagaaa tccatttcaa aacagataat caaggattgt ttgagtattc tctggcaagt
    11941 ttttctcaat atggcatgat cctcaaacag gtatggttag atttacatca aagtcaattt
    12001 gaaggcaata ttatgacgga gtatgaagaa aaattttctt caaaaggtca acgtatttat
    12061 cgagtagaag ctcaatttca agataagacc aaaaagaaaa gtctgtgaaa ctaactttct
    12121 gctttcataa aaacattaat atccataaat aaatctcaga aaatgaacat tacagatgta
    12181 atgtattttc tgggatttat ttgatttaaa atgtatttat ttcatcggtt tttccacaag
    12241 gtggaatcaa ttggaagcga gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg
    12301 gtatgacaga taatgttaag aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc
    12361 ctagttgatg tgctttagtt attaattcat tcaactgttc atagacgatc gaaaaaggtt
    12421 cctgtgtcat gattccgcct ataggaagag aaacacaagc tatttcctgc tgtttgttga
    12481 caacggtcat cccgccacct ttttgaatca aaagattagc agcatacagc atatcctcgt
    12541 cgtttgtccc aacgacaact agattatgcg agtcatgggc aatcgttgtc gctatcgctc
    12601 cttgtttcag ctgaaatcct ttcactatgc ctaatccaat gtttcccgtt tgatggtgac
    12661 gctcgatcac cgcaatcttt aattggtctt tttcgattga aggaatgaat cgttcgcctt
    12721 gtcggtccac tttttctacc aaatctttag tcactagact attcgggata atttcgatca
    12781 catgggcttg tgaagaagaa agaagcagct ctaacgaatg tggatttaat ggttgagcgt
    12841 ttagttttgg cagacaacac gtatatgaat ttgaatgatc agcaaataaa tggtcttgga
    12901 gttgcccaga ttgaacaact aatgttccct tatagaaaac ttcatgaatt ggcagcttgg
    12961 taagatcgtc tgttaagaag aaatcagctt gatacccagg ggcaatcgca cctagtgttt
    13021 tcaaatcaaa acattctgct gcattcaatg ttgccatctg aatggcttgt aatggatcga
    13081 ttccaagtgc aatagcttga cggacgatat gatcgattga tccttctttt actaaatcat
    13141 tgatcagttt atcatcggtg acaaagaagc atcttcttga attttcaggt gtgatcgccg
    13201 gtagtagcga tgccagatct tttgcaacgg tcccttctcg aaccattaaa tacataccaa
    13261 gatccaaacg ttctttagct tcttttgcag ttgtagcttc atgatccgtc cgaatacctg
    13321 ctgcaggata aacatttaac tcttccatgc cgataccagc tgcatgcccg tcaatttttt
    13381 tcttatgctg gtgcatcaat tggatctttt ctaggatgtc tgtttcatta tttgctactg
    13441 cttgatagtt catgacttca gctaagccta aaacttcggg tttttgtaaa aaaggggcta
    13501 atttttttgc atttaaattt gcaccattgg tctcaaaagg ggttacaggt acacaagaag
    13561 gtagcataaa aaagatattc atgagtgttt gtcttgcatc ttctatcata aactcaagac
    13621 ctgtactccc agcaatgttt cctatttcat ggggatctgt cactacagta gtaactccat
    13681 gaagcaagga tacttttgaa aattcgcttg gtgataaaag tgagctttcg atatgcacat
    13741 ggccatcgat gaatcctggc actagatatt gcccattagc attatgtacg ctttttcctt
    13801 cgtattcacc gattcctacg atcattcctt cgcagattgc tacatctttt tccatgattt
    13861 ctttcgtaaa gacgttgacg atcttagcat gcttgatcac taggtcagca ggcttttttt
    13921 tacttgctac ttcgatatat ttccttaatg ttgtttccaa tggagtgcct cccaagataa
    13981 atttttataa gtataacata aattcggctt ttgccaatat ttttttgtaa attcatttta
    14041 tttgaaacaa aaagatcaaa aagacgtatg ttttttgtgg aggggagaat aatggaaata
    14101 aaacgattat cggatcaaat gataagtgaa agttttgcca aacatgccca agacgtatat
    14161 atattgccag cttcagaagt attttacatc tattttcgct atggaaaaaa acgaacattc
    14221 tggaagaaag tctcttcggc agatggacag caactgatct caagatttaa gtatttggga
    14281 cagatggata tcggagaaaa aagaaaagct cagttaggtg catttactta ttctttagaa
    14341 aaacaggaag ttcgtctgcg gttgtcttct gtaggagatt accttcaacg agagagttta
    14401 gtgattcggc tattatacgg tacttttgaa acaccccatc gttgctttag ttctcgagat
    14461 tttgcaacta ttttacagaa aaccgtcaga cgtggattat accttttcag cggaccagtc
    14521 ggatcaggca agacttctct aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt
    14581 actatcgaag atcctgtaga gatagaagaa ccgttttttc tgcagctaca gatcaatccg
    14641 aaaatagcac agacttatga tacacttttg aaactcgcat tacggcatcg tccagacttg
    14701 ctaatcattg gcgagataag agatgaatca actgcacatg ctgcggtaag agcagcacta
    14761 acagggcacc gggtttttgc aaccgtacat gcacgcaatc ttgaaggtac attggtcaga
    14821 atccatgaac tgacaaagaa aaaagaagag ctatctgaat gtttagctgg tgtcatttat
    14881 caagaacttt tggaagatgc caatcaccat ccttctgttt tatggagtta tcaatttatg
    14941 gaggaagaat cagtaaaaaa atcatgggag gaaagttatg aagaagctca ggaaaatatt
    15001 tggcagtcag aactattcta aaggattaac aagaagccag caaaaccagt ttgcacaaac
    15061 catgggagaa ctgcttttat ctggttttag tctgcaagaa tccctttatt tattactcac
    15121 gatccgttcg tttccacctg ttattttggc aaatatccaa catcagctaa aggaagggca
    15181 agcgtttagt gaggtacttt cgcaaatagg atatggagca gagcaactgg tacagatcga
    15241 gttagctgaa cgtcatggga atctgccgac aactttgttg gaaattgcca aacagtttcg
    15301 gcttgttgaa ggatttcgca atgatttgaa aaagctgctt gcatatccga tgctattgct
    15361 cacctttttg ctaggtatct tgtttagtat gcggttgttc gttttgcctc agcttattgg
    15421 ttcaggaatg gtcatgcaag agcattgggg tattcagctg atacaagtct ttcattggta
    15481 tgttctacta ttcatcctag cggttactct attggcttta ctagtaaggt atcgtctgat
    15541 gaagttgtct cctgttgatc agagtgaatg gataagcaga caattattga ttggaccgat
    15601 atattccttg tatcaatcgg cttatttgtc actagagatt ggaaagcttt ttcatgaagg
    15661 tttcgaatta aggcaaatca tagtctgctt aaaggaaacg aaacaagaaa gtctgattca
    15721 gcatcttgcc tctaagttga ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt
    15781 ccagaattat cgttttctat cagaagaatt cagtaaaatt gttttacagg gagaggcaaa
    15841 gggaagttta ggtaaagaac tgatttttta cagcgaatgg acaagaaaac agcttttcaa
    15901 acgtcttcat cactggatgc attttattca gccaatcatt tttttgggcg tagcggcttt
    15961 gattttatta gtttatgccg ctgttttatt acctgtttac ggaagcatag aggaggtttt
    16021 gccatgaaaa agagaaaaat atcttattat agcggtttta cattgatcga aatgctaatc
    16081 gtcttactga tcatcagtgt attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg
    16141 aatcatgtag accaagaaag tcgtgaagcg atcatccagt tggtagacac acaaaaagag
    16201 ctctatgcgc ttcaaaataa tggaagagtt cctactgtgg aggaattgtt gaatgaaggc
    16261 tatatcaaac gagaacatgc agaaatctat cagcggcctt gaaggtaagg ttttagcatc
    16321 aggatatacg ttgtttgaat cactcttact gattttatta cttacaacga tcctttcttt
    16381 tccagttctc gcattttctg catggaagaa tgaattggca gtctatcaat ttttcggcca
    16441 atttgaaaaa cgaatctatt ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg
    16501 cttttattgg aatagtgaag agaatcaaat catttttcat gttccgaatc cagataaaat
    16561 aaattgggaa gtattagata ttcctgatga gattaccttg aaacgccatg cttctattac
    16621 ttttgctgct agaaccggga atgaaagttc actaaaagct tatcaatttt attgggaaga
    16681 aaaagagcgg acgattacgt atcaattcca gatagggagt ggtcgctata caaaaagaat
    16741 tgaataaaac aggatttgtt ttgttggagt cccttacagc gcttatgatc gcttctgtct
    16801 gtgtctactt agtgagcttt ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg
    16861 aggaactgct atttattcga atgatttatg aagatatcaa gacgcagcgg atgtatcaca
    16921 aaagaccaga gcgaagggaa gaaatgatcc catacgatat ccaaattgtc gataataatg
    16981 gagtaatcga aaaagtgttt gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa
    17041 gtaattccag catttacgct gattgaatgt ctaattggac tgatgatatt gagcagtcta
    17101 ttgctcacat tcaatctttt gattcagcaa accatccaag taagtgaatt tttgcagcgt
    17161 aaagatcaaa aagagtggct aatattttta gcacaattag aagaagaact caagagcagt
    17221 cacaatgtct ctgtgaaaaa tcagcaactg cactacacga tcgaggataa acagtatatc
    17281 atcgaaagat atcaggcaat gatacgtaaa agaagaactt ccggcggaca tcaacctatg
    17341 ttaacaagta tcactgagct tcaattattg gaaaaagaac acacaatttc tttttatgta
    17401 cactttgaaa atggagaaga tggatatgcc atatggacaa aaaacgatca gtagaaaatg
    17461 ttataagggc tctattttat tttctgtctt gcttttattt cttttatgta cgtttttatt
    17521 gatggcagca ttagaaagct accgtttgtc aatggatctt aatatacgaa tcaaaaatta
    17581 ttatatagca aaaataatga agcagatggc tttatcggaa cagtctacgc ttgccgaaag
    17641 ttcggaagga gttttttact acacaactgg atctgtaaca tatcagtggg tacaacagtc
    17701 cctattctta gaggtggaag tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa
    17761 tgatacagat actagtacag aatgatggaa tgttcgtgaa aacgccctct tttctgttat
    17821 aacactgttt ttaataaaaa aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat
    17881 tgaaattttg tcaattgttc gatagaatta aacaggtgaa aaaattgtta taatatatct
    17941 agaaatgagg tgcaccatgt taccagaaaa aatggaacaa gggtttaatc aaaacctgga
    18001 agctattcag cttttacaga atgcattggg aacttccttt ttagaagcct atgtcgaaaa
    18061 tgcagaaaat ttaatagatg attatcaagt acgtgtggtg gatggagtgc cgacaaaaga
    18121 gacaacgcaa cggatcacag ctctttatga agagttgaag aaactttctt tcgagccaga
    18181 agaatggcgc agactgtctc aattactttt attgaagggc agccagacag aacatttgca
    18241 ggcgaaccat caactcactc ctgatagtat cggtttttta tttgtttttc ttattgaaca
    18301 actatacaca aataaaaaag caccggttaa gattctggat attgcggcag gaatgggcaa
    18361 cttgttatta acagttcttt taaacctatc gaatgcgggg taccaaacag aaggaattgg
    18421 tgtggatatt gatgatacat tgttggctgt cgcagcttct acaagtgatt tgacacaagc
    18481 aaatgttcaa tactttcatc aagacgggtt gcaggaatta ttaatagatc ctgtcgattt
    18541 tgcaatcagc gatttgccaa tcggttatta tccgaatgac gaaaaagcaa aagagttttt
    18601 aacaagtacc gaagaaggcc atagttatgc acatcattta ttgctagagc aatcaatgaa
    18661 atatgtgaag ccggatggtt ttggtttgtt tttgatgccg agtggatttt tagaaacgga
    18721 tcaaagtgaa gaaatcaaaa aatggtttaa agaagaaggt tatcttcaag gaatgattca
    18781 attgccagat gaattgttcc gtaataaaca atcgcaaaaa agtattttga tcttacagaa
    18841 aaaaggacca caagcacaac aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa
    18901 agaaccagag aaggtgacgg aatttttcaa cgagtttaaa aactggaaat catctgctct
    18961 gtaatcattc aacgagaagg agagtcatat gtctaaaaca attgcaatca atgctgggag
    19021 ttcaagtttg aaatggcaat tatatcaaat gccagaagaa accgtagttg cgaaagggat
    19081 cgtcgaacgt atcggtttac aagattctat ttttaccatc aagtacggcg ataatcaaaa
    19141 attcgaacaa atcatggata tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca
    19201 gttgattgaa ctgcaaattt taagctctta tgatgaaatc accggagtag ggcaccgtgt
    19261 tgttcacgga ggagaaactt atggggattc agtagtgatc gatgagaaag taatggaccg
    19321 cattgctgaa ttagcagaat ttgctccttt gcataatcct gcaaacttaa tggggatcaa
    19381 agcgtttaaa aagattttac ctgacatttt gagtgtggct gtattcgata catctttcca
    19441 ctcaacaatg ccaaagcaaa attatttata tagcttaccg gtgtcttatt atgaagattt
    19501 caaagtaaga aaatatggct tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc
    19561 aaaattattg aacaaaccga tcgaagaact aaaaatcatc acttgccact taggaaatgg
    19621 tgtatcgatc acagcagtcg atggaggtaa atccatggat acttctatgg gattcacacc
    19681 attagctggg gtgacaatgg gtacacgttc aggtgatatc gatccagctg ttctcccata
    19741 tttaatggaa aaattagaga ttgatattga tgaaatgatc aatgttttga acaagaaatc
    19801 tggtctgcta ggcctaacag gattgtctag tgatatgcgt gatcttgaaa agaactatga
    19861 aaaagaacat attcgtttag cttatgacat tttcgtggac cgcatccgaa aatacatcgg
    19921 cggttatgtg acaacgatga atggtgttga tgcaattgtc tttactgctg gtatcggcga
    19981 gaatgacgga catgtacgta gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat
    20041 cgatccagcg ttgaatgaat tgcgtggtga agaagtagat atctctacaa aagaatcaaa
    20101 agtaagagta ttagtgatcc caacagatga ggaactaatg attgcccgtg atgtggagcg
    20161 tctgcgcggc taagccaaag cattcgttag gataaaagat gaaacgcatg caagagggaa
    20221 ttcttgcatg tgtttttttt gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc
    20281 cttctttttt acaggatctt cttagggaat tttgcttgga aaagtggtca aaagggaaaa
    20341 gactggcatt ttatttattg attttcagga aaatcccaat attttatttt cattcatctt
    20401 tataagggac attacatatg taaaaagaaa aaacattttt agatcagcct cgtgggctgt
    20461 cgactttatt cttcgcttta tgtttagcta gaaaaccgat ccgaaacatt cattgatcga
    20521 ataataaaaa cttgattttc cacctgtact ttgcctgaat cgtgaaagca caggtatgaa
    20581 aatcaagttt tttgttgcga aaaaacgtcc tagtcaatca gttggccgag cggctggcgg
    20641 ctgatctgct cctgatcaat aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg
    20701 tcatggctga ctgctaggag cgttccttga tagtcttgca gcatttcttc aatttcttct
    20761 cgagcatagc tgtcgaggtg attggttggt tcatccaaaa tcaggacgtt gattttttct
    20821 aaaaagagtt tcagcaacgc caaacggatt ttttcaccac cggataaatc tttgatccgt
    20881 ttacccacat cgctttgata aaagccactt ttggctaatt gccgtcgagc gacttcttcg
    20941 tttccagtca atgtgatggc gtaagccagc aaacggctat cgggatcggc aaactgcagc
    21001 tgctgcggca aataaccgat ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc
    21061 ttttcctcac cgagtaataa tttgagtaag gttgattttc ctgcaccatt gtcgccgatg
    21121 atggctaaat gatctccacg atagactgca aaactgctgt ctttgaatag tacttgatca
    21181 gcgtactgct ggtgcaagtt ttgaatgatg aaaacttctt tgccagattt tccaccatta
    21241 gacaagcttt gcagccgatt tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc
    21301 aggcggcgtt ccagttcttt ggcttttttg aagaaggact cattgtctcc ttcatgtgcc
    21361 cactgacgaa aacgacgaat catgactttc aaccgctgga cttctttttg ctgcagttcg
    21421 taattttttg tcagctcagc caagcgagct tctttcaaga ctcgaaaacg gctgtagttt
    21481 ccgggatact caatcaatgc accttcttcc agttcccatg tttttgtggt gacttgatcg
    21541 agaaattgcc gatcatgaga aacgaccaga accgattttt ttgtattctg taaatagttt
    21601 tccaaccagc gaatactgtt aagatctaaa tgattggtcg gttcatcgag taaaagtaaa
    21661 tcggcatcgg ctgctaaaat tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt
    21721 tctgttaacc gtgcttcctg acggtgtgga atccctaagc cttgcaagat cgctgcaatc
    21781 cggtcttcta atacgtaacc gcctagttct tcaaagcgat gctgcagctc accgtaacgg
    21841 gccagacact tctctaagtt tgtatctggt tctgtcatca atgcttcgta gcgactcatt
    21901 tgctgtttga ggtcctgtat ctcagcggca gaatggagca agtagtggtt gacggtcgct
    21961 tcggaaactg taagttcttg ttcgaccgtc ccgatcttta agcctttttt gcgactgata
    22021 acaccgctgt cgacaccttc tctgccggtc aagatttgta aaaaggttga tttgccagtt
    22081 ccgttgatac cgactaaggc aattttttca ccagcttcaa tttgacagga taaatcctca
    22141 aataatggat tcccgccgat tgttttttta atagaaattg cttgtatgat catgatctct
    22201 ctccttgaga ccactcaaaa aggccatggt tatccctggc ctgtgttatt taaactcaga
    22261 ttatcatgag aaaaatacct tgagatggcc attgatttta cgtgaattca actgttttgg
    22321 acaaacttgt cccgtcaaca gcaactgtaa aaccaattgc atggctaaat gcgatatggt
    22381 atcgttggta attttcatta cttgttattt tagtcatgcg catcatagta ttttccctcc
    22441 ttcgtgtagt tgtcttttcc agtgtacctg aaagtgtcag aaagttcaac tagcgctgac
    22501 atttacttaa tatttatcga tgtgtaattc tgtcagagag ctttttttat ctgactgagg
    22561 gtaatgtctc gtggaccaca tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca
    22621 tatggtgttt gataaaaaac tttgtctaca tgacttcctt ttgccatttg cttaataccg
    22681 ttgcattaaa cagctcttct ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt
    22741 gtggttgcaa tggcaagcgg tagcctttca tcaattcttg aatgatttac cgaatgtagc
    22801 acttgccttc tcgcggtacc cgaacccgaa ataaaatttt agtttggcga taaaatcggt
    22861 atccgccatc gatacttcat attttttcgt atcagattca tcggaaactt ccacattgac
    22921 gaaccaataa gctttggcat gcttaggtcg ttttaaacca caccagggcg actaatcgcc
    22981 ctggtgttca ctttttttat tttacttgaa ctcattgact gttttccctt tattttaaac
    23041 attataaaga ccgatgagtg cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa
    23101 aaaaacctgc cgatagttgg caggtcgtct acgtgttaag ctttggtgtg gtctttagct
    23161 ggcaattggt tttctaaatc agttcggaca acaagcacat cgcaagctgc gtttctaata
    23221 acatattcag aaacagaacc aataaataaa cgttctacag cattcaatcc tgtggctcct
    23281 aacataatca aatctacttg attatcttct gggatttctc tggcaataat ttgttttggt
    23341 gagccatatt ctacgacaga ggttacatta ttcaagccag ctttcttcgc attgctttca
    23401 taatctgcca atgtttgctt tgccatttca gtagcttgtt ctgcaagcat tccatcaaag
    23461 gatgaaacgg tttggaaaga acgtgtgtca atgacatgtg ctaatagaag ttctccgtta
    23521 tttcggatag ctacattgac cgccttttta aaagctaatt cagcttcatc agaaccatct
    23581 acggcaacca tgattttttt gtattgttgt aacataagca ttcactcctc aagtcaatcg
    23641 tattgtactc ttttattgta gaacacttta gggaaaaaga gaattattta ctgctttggt
    23701 tcagcaattt tttttgcaaa tcggatactg aaggtggcag aaacaataat tacgatcagt
    23761 aaaaagacca aggcaataaa gcgttgattg aaaaaagctg ttaaaatacc cattacgcct
    23821 aaaacagcat atgcagcacc gtaaaattgt aggaatcctt gatttttatc atttttgttg
    23881 atcaatacaa aaaagatatc ctgtttatta aataaataat agctaacgaa taataatact
    23941 aaagtggcga taatcattaa aatcctaatc atgaacaaat cctccaaaat aagcaacaaa
    24001 tagaaaaagc aatttgccaa gagcaaattg ctttattctt taaaagatgg taatctccgt
    24061 taatgccgtt gtttgtcctg tagtattgat cccgcgaatt caagcaggtg ggtcccatgg
    24121 tcgtagcttc gaactaccaa atgataaggc atgttaccag cagtgacaca agacgggtcc
    24181 caagatatca ataaaaatgt tcggtcaaca cacaaagagg acaattcgaa catcacagat
    24241 ttcccacctc tatagtagca tatgaattta aaaagagcaa tgagagagct cgcagaaaca
    24301 gaaccgtttt cttgtctagt tttttggagg atgctttttc cactctttta tacggtaata
    24361 ctgttgaccc agagcctgtt catatttccc tgtatctttt ggctgataat actgagcatt
    24421 cttcagttta tctggtaaat attgctgatt gacccaagcc tgatcaaaat gatgaggata
    24481 ctgataaccc acgccacggt tgagtgattt cgcacctttg taatggctat ctctcaaatg
    24541 atcaggaaca tctccagctt tgccctctcg aatatcagca agtgctgcat ctaatgccat
    24601 gtaggcagaa ttggattttg gcgacaagca aagatcgacg acgacgtctg ctagtgggat
    24661 acgtgcctca ggcaatccca atttttcagc agctaataca gcgttcactg tacgagccgc
    24721 agcagcagga ttacctaaac ctatatcttc ataaccgata accatcagac gccggcaaat
    24781 acttgccaga tcacctgcct caactaaacg ggcgagataa tgaagtgcag catccacatc
    24841 acttccacga atcgattttt gaaaagccga aataacgtca taatgagcat ctccattttt
    24901 gtcatgggta agagcttttc tttggacaca ttcttcaatg atcgacagtg taagatgaat
    24961 ccttccttct ttatctgaag gagtcgatag tgtagccagt tccagcccat tcaatgcact
    25021 ccgcaaatcg ccgttcgttg cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat
    25081 tgcttgttgt ccaaggccgc gttctttatc ccttaaagca tgttcgactg ccaactggat
    25141 gtcttgttct gttaatggtt tgacttcaaa gatctgtgta cggctgcgga tcgctggatt
    25201 gatggtaata taaggattct cagtagtcgc tccgatcaag atgattcggc cactttctaa
    25261 atgaggaagc agaaaatcct gttttgtttt atctaatcgg tgtacttcat ccaataagag
    25321 gatcactgta ccactcattt ttgcttcttc cgctacaact tgtagatcct tttttgaatc
    25381 tgtagcggcg tttagcatgc gaaatgcata attagtagag ccggcgatcg cacttgcgat
    25441 actcgttttt ccagtaccag gaggtccata tagaatcatg gaagagagca tgcgagcatc
    25501 gaccatgcgg cgtatgattt ttccttcccc gactagatgc tgctgaccaa cgacttcatc
    25561 gatcgttcga ggtctcatgc gataagccaa tggctgttgc ataggatttt cctccttctt
    25621 gtttttacgt cccttaatta tatcatattt agcaagatgc ctagaaagaa cagccttctg
    25681 ttgttttgtt ttcatagctt atccaactaa tattgtgtat gataaagtag gtgagaaaaa
    25741 tgacggataa acaaaagata gatgaatttt tttggaataa aacgacgcca gaagtggcac
    25801 gggatttatt ggggatgtat ttggagcatg acacaccaga aggaagatta gctggatata
    25861 ttgtagacgc ggaagcatac ctaggtccag aagacgaggc cgcccatagc tatggtttaa
    25921 gaagaacacc gcgtgtgcgg gcaatgtatg aaaaaccagg tacgatctac ctttacacga
    25981 tgcatactca tcggattttg aacatcatta ctcagccaga agggattcct caaggagtaa
    26041 tgatacgtgc aatcgaaccc gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa
    26101 aaactggtcc agatatcagc aacggtccgg gaaaattagt ggaagcatta gcaattcctc
    26161 aagaacttta tggtcagtct atagcagata gttcgttacg cttagttttt gagaaaaaaa
    26221 agacaccaaa aaagatcaat gctttgccta gaatcggtat cccaaacaaa ggtgtatgga
    26281 cagaaaagcc gttgcgtttt gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa
    26341 accaaatcga gaaagattgg ggttggagga aagaaaatga aaaagaagga tctattaaca
    26401 tatttagatg aaataattga aaaacaagtg acagactatg atgtagcttt agattgggat
    26461 acaaaaaatc atacgatcga gatcgttgtt cgcttgtttg cagaaaataa agcacaattt
    26521 gagattgatg atgcagaagg gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc
    26581 gtacttcttt ttaatcctca gaaatctgtt tttgatgaac gcaattatct agcagtaatc
    26641 ccttatgaag gaaaaaaagg gttggcaaaa tcagtagctg attctttagt ggaatatcta
    26701 aatgaagtat tagctcaagg gcaaagcgat ttgcttgatt ttttggatga agacgatgac
    26761 gaagctgtat tcgagcttca ctgggataat caacaactag cagaattagt agaagtaaaa
    26821 cagcaaaatg aagcagatac ttatttaccg tacccaagtt attaaggagt gacagatatg
    26881 aaatggaatg aagtaaaagt agaaactgaa agtgaagcag tcgaagcagt tgctaatatt
    26941 ttgatggagg caggggcgag tggtgtcgcg attgaagatt ctttagatgt tgaacatttt
    27001 cagtcggatc aatatggtga gattttagat aaaaatgatt ttacatcgct gaaagaaggc
    27061 gcactagtca tggcttattt tccggaaacg actttcttac cggaaatctt gccttttatc
    27121 aaagatcgta tcacacaatt acctgagttt ggtctagcta ttggaaaaaa taaagtaaca
    27181 gttagtgaag tagaggaaag caactgggca acagcctgga agaaatacta tcatccggtg
    27241 cgtattacgc gaatgctgac ggttgcgcca agctgggaaa actaccagac agaagatcct
    27301 ctagaaaaaa ttatcacact agatcctggt atggcatttg gcacaggcac tcatcccacg
    27361 acttccttga cattgacagc actagaaaca gtcttgcgtg gtggtgaaac attgctagat
    27421 gtgggaactg ggtcgggcgt gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc
    27481 tatgcctttg atttagacga agtagccgtt cgttcggcga aagaaaatat ggatatgaat
    27541 gaaatagcca aagatgtcca tgtatcagct aacgatcttt tgacaggaat cgagattgaa
    27601 agtgatgtaa tcgttgcgaa cattttagca gatatcatct tattgatgat cccagatgct
    27661 tggcgtttac tgaagcaaac aggcacgctg atcgtttcag gaatcattga agagaagaag
    27721 caaatggttc tggatgccat gttagaacaa gggtttatcg tggatcaaat tttccagcaa
    27781 aaagactggt atgcaattat tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt
    27841 ttaaaagaat catatgaatc aaaagactat tttgttttag aaggggaaaa ctatcaccac
    27901 attgtacggg ttatgaggat ggaacccgag gatgaagttt ttttggcatt caatgatcaa
    27961 atagccattg ttgcagaaat cacggagatt actgaagagg ctgtttatct gaaagaaatt
    28021 aaaaaagaag aaaatcaaaa ggaactgcca agttcgatta ccatagcgag tggctatcct
    28081 aaaggggaaa agctggattg gatcgttcag aaatccactg aattaggagc gcaagctttt
    28141 cttggtttcc cggcatcagc ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga
    28201 caacaacggc ttgaaaagat tgctcaagag gcagcggaac aatcccatcg gcagatcgtg
    28261 ccatcagtag agttattgga aacgaaacaa gatttatttg agcggctaga tgattatgac
    28321 gtggtcttgg ttgcttatga ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa
    28381 attcttagtg aaacaaaacc agatagtcga atcttagctg tctttggacc agaaggtgga
    28441 ttatcccgcg atgaagtcga ttattttgta gaacacaaag ggatactttg tggattagga
    28501 ccaagaatcc ttcgtacaga aacagcacct ctttatttat taagtgctgc tagctatcaa
    28561 tgggaattaa tgaatccttc tttcagctaa cgttcttcat taataaaaga gtatcgacag
    28621 aaagaattga aaaaatagtc aacaatttgt ataatagaaa caattattta tacaatggat
    28681 acgaaaaatc gtttgaaaaa gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac
    28741 tgcacggatt ttgggacaat tatcaaacag atatttgtcc cgattcccgt tttaccgaaa
    28801 aaagaaaggg ggatcgattc ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat
    28861 aaagctcgtt agtcaataca tgggtcccga acatgtagca tttgttgaga aagcatgcga
    28921 atacgcgact gctgcacatg acggacagtt tagaaaatca ggcgaaccct acattattca
    28981 tcctatccaa gtcgcaggta tattagcaga tttaaaaatg gatccccata cagtggctac
    29041 aggcttctta catgatgttg ttgaagatac agaaatcact ttagaagatc tgagagaaga
    29101 atttggcgat gacgttgcta tgttagtgga cggcgtaacc aaattaggga aaataaaata
    29161 taaatcccac gaagagcagc tagcagaaaa ccaccgaaag atgctgctag caatggctca
    29221 agatttacga gttatcatgg tcaaattagc tgatagacta cataacatgc gtacgttgaa
    29281 gcacctgcga gaagataagc aaagaaggat cgctcaggaa actttagaaa tctatgcgcc
    29341 tcttgcacat cgtctaggga tcagccggat caaatgggaa ttagaagata cagcacttcg
    29401 ttatctaaat ccaaaacagt attaccgtat cgtccacttg atgcagacga agagagaaga
    29461 acgtgaaaaa tacgtaagtg gtactgttga agatattcga atagcgacag aagagctggg
    29521 gatttttgca gaaatctatg gacggccaaa acacatttat tcaatctatc gtaaaatgaa
    29581 agatcagaaa aagcagttca acgaaattta tgacttgcta gctattcgag tgatcgtaga
    29641 ttcaatcaag gattgttatg ctgtattagg agcaatccac acaaaatgga aaccaatgcc
    29701 cggcagattt aaggattata ttgccatgcc aaaagctaat atgtaccaat ctttgcatac
    29761 taccgtgatc ggtccggcag gaaatccggt agaaattcaa atccgaacac aggaaatgca
    29821 tgaaatcgct gaattcgggg ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa
    29881 agtagaacca gatggtatga cgaaacaatt aagctggttc catgagatac tcgaacttca
    29941 agacgaaagc tatgatgctt ctgaatttat ggaaggcgta aaaggagata tctttagtga
    30001 taaagtctac gtcttcacac caaaaggaga cgttactgag ttaccaaaag gatccggacc
    30061 attggacttt gcatacagta tccatacaga tatcggtaac aaaaccactg gtgcaaaagt
    30121 aaatggcaaa atggtgcagc ttgattacaa attgaaaaac ggagatatca ttgagatcat
    30181 gacttctcca aattcatttg gcccaagtcg cgactggttg aaattagttg ctactagcaa
    30241 agcaagaaat aagatcaaac gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa
    30301 aggccacgaa tccgtggtca aatgtattac agatctagga tttacgccta aagatatttt
    30361 gacgaagaac aaactgcaag aagcactcga tcgttttaat tatcaaacag aagatgatct
    30421 ctatgcagct gtagggtatg gagaagttag ccccttgacg atggccaatc gtctgactga
    30481 aaaagaacgt aaagaacaaa aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa
    30541 tcagccgaaa aaagaacctg acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca
    30601 aggggtagaa aacttactaa ttcgtatcag tcgctgctgt aatccgattc ctggtgatga
    30661 tatcgttggt tatatcacta aaggcagagg gatatccatt catcgtcgag attgtccgaa
    30721 tgttcagcct gacaaaccaa atgtagcaga acgtttgatt gaagtcgaat gggaagatac
    30781 atcgaataca cgaaaagagt atgatgcaga tttggaaatt tacggctata atcgttcagg
    30841 cttattgaat gatgtacttc aaacagtcaa tgcgctaacg aaaaatctca acagcgttga
    30901 agcacggacg aataaagata aaatggcgac gatccatttg acggttggta tccagaattt
    30961 atcccaccta aagagtatcg tggataaaat caaagcagta cctgatgtct acagtgtacg
    31021 ccggacgaat ggataggagg acagatatga gagcagttgt tcaacgggta agtaaagctg
    31081 ctgtgtcagt cgatcagcaa gaaattggaa aaattggcta cggcctactt gttttattag
    31141 gcattcatga aaccgatacg caaaaagatg tggactatct ggtaaaaaaa attgcacaaa
    31201 tgcgtatttt tgaagatgaa caaggaaaaa tgaatattag tgtagaagat gtgggaggac
    31261 aaattttaag tatctctcaa ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa
    31321 gctttgtgga agccgcacga ccagaaacag ctattccttt atacgaatca ttcaatgaag
    31381 gaatcagaag tcgcggcatc acagtcgcta ccggacaatt cggagcagat atgtcggttt
    31441 ctctcgtcaa tgatggacct gtaacgatca ttattgattc taaaaacaaa taaagtaatc
    31501 tggttttcac tagtaaaaac tatgaaacac gtcgcttaag ttagactgat aaactctaac
    31561 ttaagtggct tttttgtctg caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta
    31621 agcttaaatt atacaagtta ttttttatag gaggttgctg aagatgaaag aagtaccagt
    31681 agtagatatc aaaatcacag atttaaaaaa attgtatcaa aaaggataca acatgttgga
    31741 ggagttacgc catgaagcgg acgctcccgt cgtcaaagca aagattttca ataaagaagc
    31801 tatcacgatc tacggatcat cagcagcaaa agtattttat gatccaagga atttcaaacg
    31861 aaaaggtgct atgccaaaat tagtattgaa gacacttttt ggtcaaggtg gagtacagac
    31921 tttggatgga gctgctcatc accatcggaa aaatattttt atggatctaa tgacaccgga
    31981 aagaatggaa gattatcatc gtatcttaga taagaatctg acacaagcac ttgaagcaca
    32041 gcatggtcaa tttgaactat ttgatttaag taagatggtt ttctttacat ctatttgcga
    32101 gtgggcaggt atcaatttat cagcgatttc taaagatgag gtcgaaaaat tagcagaata
    32161 tcaaatctct atgatcagcg gaacgtttac ttctccgatt gatcacataa aaggtgtcga
    32221 gaatcgcaaa aaatcagaaa aatgggcgca aggcttgatt gaagaagctc gacaaaatcc
    32281 tgtggctgga aaagaaaatg tggcattata tgcttttgcc aatgccacag atttagatgg
    32341 tcagctttta cctctggaag tggcagctgt tgaattattg aacatcatcc gtccaacggt
    32401 tgctctaact gtgtgggcgg cattgatggg acatgcactt ttcagtagac cagatttgta
    32461 tcagcaatta aaaaatgact tttcgacgtt acaagatccg tttattcaag aaatgagacg
    32521 ctattatcct ttcttcccaa tgctacctgc gatttcgctg aaagaagtag aagtagatgg
    32581 ttatcgtata ccagaaggca gttgggttat tttagattta tatggaacag accatgatga
    32641 acgaacagtt gaagcgccag attcctttat gatcaaacgg tatgtaggga aagcaaaaga
    32701 tatttcctat aaagaagaat atgagatgat tgcacaaggc gggggaaatt ttcgacaaat
    32761 gcatcgctgt gcaggagaat ggatcactct tcatagtcta cgtgtgtttt ccgatcagct
    32821 agtaaataag tttgagttct ctgtacctga acaagattgg acgattccat tcaatcagtt
    32881 tccgacttat ccgaatagcc gagcgctact ttacaagaat tagattagca taaacttatc
    32941 gaaaaaaagg aagatcaaac agtgctgatc ttcctttttt catattacta taaattgata
    33001 aggtcaattg atcaaaatcc acgaaatgct tcatcaatgg tttgataatc ttcattggat
    33061 aaatgcaaat ctaaagcttg gacattgtca gatacttgct ctggacgctt agctccaggt
    33121 ataactacag acactcgtgg attcttcatg taccaagcta aaacaagttg cgcaggagtg
    33181 gcttggtatc ttttagcaat ggggcgaagt acatcgacag cggttaaaat ttctctgaaa
    33241 cgttctcctt ggaaatctgg atttcttttt cgaggatctc cttcaccaaa ttgtttttcc
    33301 tcaccaagtt catattttcc tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa
    33361 ctgattttgt ttttttcaag ataagggaat aattcttttt cagcctgccg atggatcaaa
    33421 ctgtatttat cttctactac atcgacatat ccatctgcat tcgcttcttt caattgttct
    33481 aacgtgaagt ttgacacacc gactgctcgg atttttcctg cttcttttaa ttcgtgcaat
    33541 gtagcaactg attcattttt tggtgtgctt tcatccggaa agtggatata aaaaatgtcg
    33601 atgtaatcag tttgcagacg ttttagtgca tcttccaccg attgtttgag aaactcagga
    33661 gaattatcaa atgttcgccc tttatttggt acatgagcag cttttgtagc gatgacgaca
    33721 cgtgagcgat catattcttt ttccttcagt acctcgccaa tcagttcttc ggaacggccg
    33781 tttccgtaag cataagcggt atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact
    33841 acttgttttc ctgtctcatc ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt
    33901 gctcctaatc caagctgttc tgcgtagact tgtgaatgtc cgattcttat ttctgccata
    33961 gctgattcct cctttttgtc tagtctaaaa caaaatacca aaaagctgaa ctaaaacgtt
    34021 tttgtgaggg gaaatagtca gatatctctt gactttgaga ctggttttta gtaggttata
    34081 agtaatatcg aatgtcaatg aaagagcgag taagtttttg aaactttaca agagaggatc
    34141 atcgaggctg aaaatgatct aaagtttcat tagcctaaag acactctgga gatggacgag
    34201 tgaaaagccg tcccgcgtac gagcgttatt cgtaagagga aagagaaatc tttcaaaatt
    34261 aggtggtacc gtgtatgaat ttcattcacc cttgttcatg atgaacaagg gtgatttttt
    34321 tatttacata gctaagaaag ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa
    34381 atgatatttt gccaggcgaa tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat
    34441 tattcagaga ttatcagtat aatgaaatgc gtacaccgat ttttgaacac tatgaagtga
    34501 tatcccgaag tgtaggggat acaacggata tcgtttcaaa agagatgtat gatttttatg
    34561 acaaagggga acgccatgtg acgcttcgac cagaaggtac agcaccaatc gttcgttctt
    34621 ttgttgagca taaattgttc ggcccagagt atgcgaaacc gttcaaaact ttttatatgg
    34681 gaccaatgtt tcgctacgaa cgccctcaaa aaggacggtt acgtcaattc catcaaatcg
    34741 gagtagaagc atttggatca gaaaaccctg caactgatgt ggagagcatg gtgatggcac
    34801 ttgatttctt caaacagttg gggatcacgc aaatccggct agtcatcaat tcattaggtg
    34861 ataaagaaac gcgtcaagcc tatcgtcaag cattgatcga ctatctttta ccttttgaat
    34921 cagagctgag tgaagactct aaacgccgcc ttcatgaaaa tccattacgc gtattggaca
    34981 gtaaagacaa acgagatcaa aaatttgtgg cagaagctcc atctatctta gattatctaa
    35041 gcgagcctgc tcaaaaacat tttgataccg ttgtttccat gctggatgca ttggctgttc
    35101 cttatgaaat cgacagtaat atggttcgcg gactagatta ttacacacat acgatttttg
    35161 aaatcatgag tgacgcacca aaaatggggg cacaagcaac gatttgcgca ggcggacgtt
    35221 atgacaatct agtggaagaa ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg
    35281 gtatcgagcg attactcttg actatggagg cagaggaagt agttatccct gcatttaatg
    35341 agttggatgc ttacgtggtc gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg
    35401 tccaagcgat tcgaaacttt ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa
    35461 aagcgcaatt taagacagca gataaagcga atgccaaatt agtattggtg atcggtgaag
    35521 atgagcttgc tagtcaaacg attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt
    35581 ttccattaga agagatatat gaacattttg atgaagtcta tgatgaaatg actttattcg
    35641 agtaggagga aaaaaataaa tggcacaaag aacgatctat tgcggattag tttccgaaca
    35701 acaattagaa caaacagtta cattaaaagg atgggtacaa aaaagacgag accttggggg
    35761 agtaatcttt atcgacctac gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga
    35821 aatcaacaaa gaagcatggg aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt
    35881 gactggggaa gttagaagac gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga
    35941 attcgaagtg attgcaagtg aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca
    36001 aattgaagat gatcaagcaa tcagtgacga aatacgtttg aaatatcgtt atttggatct
    36061 gcgtcgtcca aaaatgacta aaaacatcaa attaagaaat gcgacaacaa aagcgattcg
    36121 tcattattta gatgataatg actttctcga tatcgaaaca ccttacctag ggaaatctac
    36181 accagaaggc gcaagagact acctagttcc ttcacgtgtc catgctggac atttctatgc
    36241 gttgccgcaa tctcctcaat tgtttaaaca attgctgatg aatgctggat tcgaccgtta
    36301 ttatcaaatc gttcgttgtt tccgcgatga agatttacgt ggagaccgtc agcctgaatt
    36361 tacgcaagta gatattgaaa caacgttctt aacagcagaa gaaatccaaa cttacacaga
    36421 gggattgatt gcgaaggtaa tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc
    36481 tcgtatgacc tatgatgaag caatggctcg ctacggcagc gacaaaccgg atacacgttt
    36541 tgatatggaa ttgatcgatc taagcgatac agtcaaagaa gtagaattca aagtcttcca
    36601 aatggctctt gaaaacggcg gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg
    36661 ctactcacga aaagacatgg atcagttagg tcaatatgta ggacaattcg gagctaaggg
    36721 gcttgcatgg ctgaaagtag aagaagacgg attgaaaggt ccaattgcta aattcatggg
    36781 agaagcaaca gaagcaatca ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt
    36841 tggcgcagat aaaagtgaaa tcgtcgctgc tgcattaggt gctatccgga cacgtttagg
    36901 aaaagaatta ggactaattg atgaatcgaa attcaatttc ttatgggtaa ctgattggcc
    36961 acaatttgaa ttttcagaag aagaaggtcg atatgtctct gctcaccatc cattcacgat
    37021 gccaaaagaa gaagatatcc cgttattggc tgaagaccct gcaaaagtct atgcagaagc
    37081 ttatgatatc gtcttgaacg gttatgaatt aggcggaggt tctatccgta ttcatactcg
    37141 tgagcttcaa gaaaaagtac tagaaactct aggctttaca aaagaacaaa tggaagaaca
    37201 atttggtttc ttgttaacag ctttagatta cggattccct ccacatggcg gtattgcatt
    37261 aggattggac cgttttgcaa tgttattagc cggagaagat aatattcgtg aagtcattgc
    37321 ctttcctaaa aacggaaaag cagcagatgt gatgagtgat gcaccaagta tggtttcgcc
    37381 tttacaattg ttcgaattga atattgatgt aacgaatata gaagaatagc cgataaaaag
    37441 gtaaaaagga tttgtcgaat acgcttcttt tgacaacctt gatttaattg aaaaacactt
    37501 tataatgaag ccataacata taaagcgggg cttttccatg aaaaaaacat tcgaaaattg
    37561 ggcttatcat gattacacga ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc
    37621 agtcgcattg aatttctttt atcagccagg acatatttat tcaagtggta ttactggtct
    37681 agctcagatt ttgacgactt tgtcaaaatc actgatagga ttcgaagtac cggtatcaac
    37741 aactttgtat ttactgaata tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa
    37801 gtttacaatt ttcactttta tcacagtcac tttgacctcc ctttgtatcc atattttacc
    37861 ggaaacagtc ctatctaccg atccaatcat ctgtgcgttg tttggggggg ctgtgatggg
    37921 actaggtatt gggctagcgt tgagaaacgg cctatcatcg ggcggtctag atatcgtgag
    37981 tatcacgatt cgtaaaaaaa caggaaagtc gattggttct atttcgatct acttcaatgc
    38041 attgatcgtt tttgttgccg gaattctatt tggctggcaa tatatgtttt acagtacgtt
    38101 gtctattttc gtcagtggaa aagtaactga tgtcgtttat actaaacaaa agaagatgca
    38161 ggtaatgatc gtaacgaaac atccagaaaa agtagtaaat gaaatccaaa actgtatgcg
    38221 tagagggatc acgatcatca atgaagcaga aggtgcttat aagcatgata agcagacagt
    38281 attgatgacg atcgttacac gatacgaact gcctctactt agagaagcaa tgaaagcttc
    38341 tgatccacaa gcttttgtaa gtattgcaga aaacgtccag atacttggtc gtttctatga
    38401 ggatggcatt tagatcgagt ttgacaaaaa ttcatgaaat actgctgtag acagacgttc
    38461 gtttgtctgc agtttttttc taccatagta gaatcagcaa agaaaaactg cttttttatt
    38521 tgaaattttc ttaaagttga aaaaaagcat gtttattttt ttaaatttat gggatgatag
    38581 aaaaaaatag tagagaaagg acacgattct acttgctatt ttcacttaat acccgtatat
    38641 tacgaatgaa aaaagtttat gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa
    38701 aaaacagccg ctacatcact gggtttgatg ggctccgttc attagctgtg gtgggtgtta
    38761 tcttctatca ccttctgcca actagtatga aaggcggcta tttgggcgtt ccgatttttt
    38821 tcgtcgtatc tggttatttg atcacggatc tgctgcggca ggaatgggaa caaaatggaa
    38881 aaatcaatat ttggcaattt tatgtcagaa gaatgaagag actctatccg gcacttgttt
    38941 ttatgcttgt gacagcttcg gcttatatca ctttgtttca gcgagggctg ttaaacaatc
    39001 ttcgaggagt tgtggtcagc agcttactgt atgtcaacaa ctggtggcaa atcaataacg
    39061 gtttatctta tttcgatcga tttgctaatg agtcaccgtt tacgcatatc tggtctttag
    39121 cagtagaagg tcaaaactat ttggtttggc cgatcttgtt tgtattgttg atggtatttg
    39181 ttcgtaaaag aaaatggatc ttttatactg tgttaggtac atccttcctc tccgccatct
    39241 tgatgatgat cttgtataca ccaggaggcg atccaacccg tgtttattac ggtaccgaca
    39301 ctcgtctgtt ttctatatgg ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt
    39361 taaagaaaaa catcccgaaa caagcgaaaa atattctgaa tatcgctgga ggaatctcgc
    39421 ttttggcact gattctttgc ttcttctttt tagatgatca ttacaatttc atctattacg
    39481 gaggaatgct cctagtgagt ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg
    39541 gagcaagttt gaatcgatgg ctgacaaatc cagtatttac ttggattggc aaacgaagct
    39601 atggcattta tctgtatcag tttccagtta tgatttttta tgaagcaaag gtgactgata
    39661 ttgccgatca tgttttgttg catactttag tggaaatcac attgattcta atcatcagtg
    39721 aactttctta tcgatatgtg gagcgtccgc tagcacgttt tgattatggt cgtacattcc
    39781 aagtgatgaa aggatggttc agcaaaccga tcatcagtaa gagcaaacca tgggttgttc
    39841 caggcacatt acttgtagca attgcactcg ttggtttcgt tacggcaccg aaaaacgctg
    39901 taacagccga tcaaaaacaa ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag
    39961 aaaccagaaa caattcagaa aacaccacta gttcggttga ccaagcgatc cttgataagt
    40021 acgagttgtc caaggcacaa gggaataagg cacaaaaatt agaactaacg gcatttggtg
    40081 attcagttat gttggatgct gcaacggatc tacaagaact ttatccaaaa gtagtggtag
    40141 atggagatgt cggacgacaa ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac
    40201 aagatttgtt gaaagacact gttctgattg gactaggaac gaatggctca ttctcggaag
    40261 ctcagtttga tagtgtgatg gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc
    40321 gagtaccgac gaagcgctgg caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa
    40381 aatacgacaa tatgacgctg attgattggt acagctacag taatgaccat agtgactggt
    40441 tttatgatga tcaagtccat ccaaatcctg aagggatgac acattacatt cacttagtca
    40501 gcgaagcctt gctaggagga agttcaagta cgaacagcag tgagacaaac gtgacagaat
    40561 gatagctaca aaaaacttca ggcaaaaaca tttgtttttg cctgaagttt ttttatattt
    40621 accgtgtttt taacattcat atagattcag gaagcaaaac ggttgagtgt gtctgtaaat
    40681 aacgttcttt ttgttttcgg gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc
    40741 ttcttgaaga aaatacttct gcatggatca tcttaacagg tcttcttttt tgaagacgag
    40801 tatatttagc accagtacca ttgttatgtt cctctaatcg tctagaaaga tcggttgtat
    40861 atccaccata aaatgtctga tctttacaga ataatacgta aaaataatgt tcatttgcca
    40921 tagagcatct cacgaatctc tgcagtgtat tctccatcca tattgtaagt gatcaatggt
    40981 ggagcgactt tgaatccgtc taatttgcct tctttgattc cttcaactaa caaaatattt
    41041 gcctcttttc caggttttgg gtaaacaaat tggatccttt taggtgcaat tcgatagtct
    41101 tccatgacct gaatgatttc taagaaccga tcaggacgat ggaccatagt aaagcgtcca
    41161 tttgttttta gtagcttact tgaaatatcg atcacttctt ctaacgtcgt atgaatctca
    41221 tgacgggcga ttgccaggtg tttattaggg ttcgttttat ttgttggcag ccctttgaaa
    41281 taaggtggat tacagacgac taagtcacaa gaattatgtc gaacgacaga taagctgtct
    41341 ttcagatcga tggtgtggac agtcatttgt tcatttaaat ggttaagcgc gatactacgt
    41401 cttgccatgt ctgctagacg aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt
    41461 ttacttaaaa aaagtccaac tgcgccattt cctgcacaaa ggtcaacaat cttccctttt
    41521 ttaggtacac gggaaaagtg agcaagcagc acagcatcta aagaaaaaga aaacactttg
    41581 gaactttgga taatcttgat atcttctgcg tataattggt cgattcgttc gtcttcgtga
    41641 agcatggatt ccctccaaaa tgaaaaaaat agtcgtctgt attatactat ttttattaaa
    41701 aagaaccaag gtggcttgtc aaacctctat tttttatgca tactatgacc ataagaaggg
    41761 aaaggaagag actatgtttt atcgatttat gcgcggggta gttcgagtac tattagcctt
    41821 agttaatgga aatgcccgct atgagaataa agaagtttta ccgcaagatg agaattacat
    41881 actagttgct ccccatcgta cttggtggga cccattatat ctggcggtag ctgcagcacc
    41941 caaggaattc agctttatgg caaaagaaga actgttcaaa aatccagttc tgcgatttat
    42001 attaactcga tccaatgctt ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa
    42061 aacacctgta aagattttga aatcgacaaa tttgagtttg atcatgtttc ccagtgggac
    42121 aagacatgct acagaactta aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa
    42181 aatcgtgcca gctgtatatc aaggtccgtt gacacttggg gatctgttca agcgtcagag
    42241 agtgacagtg cgtttcggcg aaccaatcga cttatcagat atcaagaaaa cggataaaga
    42301 aggtatggcg gagatcgaac gacgaacaca agcagctttt gacaaattgg acaaagaagt
    42361 gaaccctgat ttcaaatatg aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg
    42421 gtcttttgaa tctactgtcc tgttcagttc agactttttc aatgaaaacg agggagagac
    42481 gtcaagtctg ccctcttttt gcgttccaat atgtaaaata gaagacaggt gtcatgtaat
    42541 ggatcaaagt gttataataa ttagaaggac attttttgag gtgattgaat gcgtttttta
    42601 catacagccg attggcatat cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag
    42661 cgtcatgtac tatcttctat actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg
    42721 attgccggag acttatatga taggagtgtc ccagctgttg atgccgtaga attatacaat
    42781 gaattgatgg tcgattggaa tttaaaggaa aagatcccga tttttgctat atcaggaaat
    42841 cacgatagca gtacgagact ttcagcgggt acgccatggt tcagttattc gaactatttt
    42901 ttgcgaacac agctagcaga agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc
    42961 tttcttcctt actttgaacc aattgcagcg agattatatt ttgaagatga caatatccga
    43021 acgatcaagc aagcggtagc caaggtgata gataaaatgc aggagctatt tgattcagaa
    43081 aaaaaacaag tattgattag ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa
    43141 acgaaaatcg aagtaggcgg gttggattcg atccctggtg aactacttac accgtttgat
    43201 tatgtagcac taggacattt gcataatcaa gctgctttga gacaggataa tgctcgctat
    43261 agcggttccc cattgaaatt ctctttatct gagatcaacc aaaaaaaagg cgtatggatc
    43321 gttgacctga caacaggcct ggagttgaat tttagggaga tcgaacccct gcatgatatt
    43381 gaagaaataa cagcgagttt caaagaattg ctggatcctg ccttttatca gtccgtcaat
    43441 cgggagaatt acatctatat ctatctcact gatagaacga tcatcccgaa tatgatgaac
    43501 cagcttcggc aaatatatcc tcgtattttg gggattgaac gggcaaacgg tcgagcagaa
    43561 caaacaaagc gcaaacgaaa agtactagaa atgaaagatc ctcaaaaatt agcagaagca
    43621 ttttttagtg aaatgacgga agagcagcta actgcaaacc aagaaaaatg gctcggagaa
    43681 acgttgcaag aaatcatgga aatggaatga tcaagaatga aaccgaaaaa attacaactt
    43741 aaaaattttg gtccttttat caatgagacc gtagattttt cacgtttgac agaagcaccg
    43801 ctttttttga tcagcgggaa gacaggagct ggcaaaacga cgatttttga tgggatcacc
    43861 ttcgcacttt ttggtgaaac ttccggaaga cttcgctctg gaaaagagat gcgttctttg
    43921 tttgctacac cagacgaaga aacaagcgtg actttttctt ttgaacatca gcagatgagc
    43981 tatgaaatcg aacgaaaacc agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa
    44041 aaacaggcag ccaaagtaac gttgaccatt tttgatggga aaggaaaaga aataaaacaa
    44101 atcacaaaac gtacagaagc agatcagttg atcagagaac tgatgaatct cgatgcgaaa
    44161 cagttttctc aaatcgtttt actaccccaa ggagaattcc gtaatttttt ggtttcatca
    44221 agcagtgata aagagactgt tttacgtcat ttattcggta ctcaattttt ccaacagttc
    44281 aatgagcgat taaaagaaaa agcaaaacaa cagcaacaaa aattggatca tttagagcaa
    44341 gagctgcatc ttctgcaaaa aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg
    44401 tttgaagccg ttttagccca atggacaaac catcaggcaa tactcgaaaa acaaatcacg
    44461 gaagaaaaag aagctctaac ggaacttcag gaaaaacaaa agcaactaga aaattcctac
    44521 tatcgttttg aaagcttgaa aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa
    44581 aaggaattag ctgctcaaaa agacgaaata gaggaaaaga aacgatggat tgggtattat
    44641 gaatttacgc aacgattagt cgaaccaatc cagcgcctac aagaaataaa agttgaaaaa
    44701 atagaactgt cacaaaaaag tagtgagcaa acaaagaaac tagcgatgac tacgcagaat
    44761 tatgaagagt ggcaaaaaaa tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa
    44821 gctgctcaaa aactgcaaaa caaacagatg atggtgccaa ttgtcgaatc cttacgtagt
    44881 aaaaaacaag acgcagaaca attaacaatt tcattggata aagaagaatt gaatgccgag
    44941 aagctgtatc aaaatctcgc tatctatcag gaaagaactc gaattcttca agaaaattta
    45001 ctggatcagg aaaaactgca agaagatcgt cttgcttttg gacagttaaa atatctagat
    45061 gaaaagcagc aagaaataga aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata
    45121 agagaagaac tcaaaaaagc aactgaagaa ataacaaaaa atagtcagct attgaaagaa
    45181 cagacagaac aagcagaaca gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt
    45241 cagctttttt tgcgtccagg ggagccatgt cttgtttgtg gatcaacgga acaccccata
    45301 caacaattaa aacacgaaca gccaaataag gaagatatct taaaagtaga acaacaactg
    45361 gcagaagctg agtctgctgt agaaagaact cagcaaatca ttgccaaaag tgaagcacat
    45421 gaaaataatc ttcaacaaca attatcagat ttagaacaaa aaatcatggc aacgaatata
    45481 caattggctg aacaagaaga acacttgcaa caggctttga aaaaggcatt tcctgagata
    45541 acagaacaaa aaacaaaaac aactcttgta gtaatcgaac aatctttaga tagacgaaaa
    45601 agcaagatgg ccaatgcaag aatagagctg gaagaaataa gacaacaagc agaaaagctc
    45661 gaacaacaat tagctgtcta caaacagcag cagacagaaa aaaataatca gctccagcaa
    45721 ctgcaaggag aaatcaaaag tttagaacaa caattgcaag atacggatag taactgttta
    45781 gaagaggaga tacgacgact tgaaaaacag ttagaagaag actcgaatca actagctgtt
    45841 gagcagaaag caggagtgca attgttgcaa gatcttcata cgcttcggac acagcttaat
    45901 cttcaacatg aacaaataga aaaaatagat gaaaaaatag aaaaggaaca agaaagaata
    45961 gctaaaaagt tagaaagcca gtcgtatttt tcaacaattg aagaaatctg tgcatttgca
    46021 caacagcaag cacaatataa agaaaaccaa cgtacagtta cttcttatca tgaagagcaa
    46081 ttagtgacag ctgaccggct gcgtcaatta gaaaatatcc agctaactga gacattccca
    46141 gatacagaag agatcagcca acagttagaa gaaataagac gtatgatcga aataaagcaa
    46201 gaaaagatat acggtttaca agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt
    46261 ctttcgattt atcacacaag ccagacgaaa ttagatgagc ttacgcaatt acagcagctt
    46321 tcgcaaacat tcaacggaga aaatcctaag aagactagtt tggaacggta tgtgcttcag
    46381 gtttatcttc aagaagtgtt acaagtagca aatgatcatc tccaacgttt aacgaaaaat
    46441 cgttatcaat ttgagctagc ggataccatt ggcagttatc gagggaaaac cggattagaa
    46501 atcaatatct atgatgatca ggcaggtatg tctcgaagtg cgcataccct gtctggcggt
    46561 gagagtttta ttgcagcact ttctttagca ttagctcttg ccgatgtgat ccagacacaa
    46621 gctggtggtg tagcaatcga tgcattgttt attgatgaag gatttgggtc attagatgaa
    46681 gaagctttgg aaatggcaat ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc
    46741 ggcatcatta gtcatgtaag agaattgaaa gaacgagtat tacaacaaat aagaattgat
    46801 acagaaggta gcggacaaag caaaatacgc tatcaacttg gataaaaagg gagattggta
    46861 actatgaaat ggagtattcc agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa
    46921 ggccgagtgt tatcggttgt ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg
    46981 ggcagtgaat tgtatatggt tgatttggat ggtacagcaa aagagataga ttactgccaa
    47041 tgtccctatt gggaggaaca taaatattgt aagcatacag ttgctgtgga actttattta
    47101 cggtcgaaaa atctatctcg tatcatgaaa aaagaccagc caatgctaga accggtaaaa
    47161 gcaacaagtg agggagaaat cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat
    47221 cctcaagcgg tgcaaccttt gattattgaa taccaagtag aaacgattga gactaatcag
    47281 tatcacccag agctttctat tttggcactt tacttgcgta tcggttcatt ggcatcaccg
    47341 aaaaaaacat atatcgtaaa aaacatctat gattttttac aagcttacac agaaaaagaa
    47401 acttacactg ttaataaaca gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa
    47461 gatcaaaaaa tactcacgca tcttgcagga agtgctcaga cgcatcaatt attaggtacg
    47521 aacggcttac aagtcaaagg aaaactagat aaaagatatc tgcttctccc agtagaacaa
    47581 gcccgcttcc tgttagagca gatgaatcag actacacgtt tgcatctgca gataaatgaa
    47641 caaaacgatc aaggaataca attttccgat caaaacaaac ctttatcatt caaagtggaa
    47701 aaatttggag aagattattt gctgcaagca ttgaatgatt ttgatttttt ctttatgcat
    47761 tatcagtggg gagttatcca agggacattt tattctctga cgaaatatca acaaacggtt
    47821 tatcaaactt ggaaacaatt gattcgccga ttggagaaac cagaagtagt gttcaagaaa
    47881 aaagaattac cgtctttgtt taaagagatt atccctctgc tgtcagagat cggcgacgta
    47941 gctattgccc ctgcagtaga agaggaagta gcagatatcc ccgtcgaatt tattttcttt
    48001 ttccgaaaag caaaaggaaa aatccaagct cgagtcgatt tcgtctatgg tgaagtcatc
    48061 tattcgactg acccgaagca tgaggtctcg acagaacagg cttttcaggt gttacgtgac
    48121 acagtagaag agaaacgagt acttgatcta ttcagaatgt atcgctacca gaaaaatgaa
    48181 actggttatg aacgtccatt gccaagcggg gaagaactat atgccttttt ccgcacagaa
    48241 ctatctgtct tccatcagtt tggtgaagtc agacttggaa gaaaattgcg agagttgtat
    48301 ttagatgcgc ataaacatca accgaaaatc gaagtaaccg agaccggttc atggctcgat
    48361 attcgattcg atgtgacagg gatagaggag caagaaatcg atcatgtcct gcaaagcttg
    48421 ctgagaaatg atgcttttta tacattagaa aatggtcagg ttctttcttt tgattcagaa
    48481 gaatttcaac aaacaagcca agtgttgcaa caattacggg aatcgatacg tacagaagaa
    48541 ggaacgatcc atgtacctaa aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc
    48601 aatgctactt ttagtgaatc gttccaaacg atggtacaag atctcattca tccagaaaga
    48661 taccaggcac agcttcccaa aggattgaat gcaacgatga gagattatca aaagcaaggt
    48721 tttcgatggt tgaagatgtt aggtcattat cagtttggcg gtattttagc cgatgaaatg
    48781 ggacttggga aaacactaca gacaattgcc tttttacttt cggaaaaaga agaacggaaa
    48841 agcttctctg ctttgatcgt agcgcctgcg agcttaattt acaactggca ggcagaggtg
    48901 agaaaattcg ccccttcttt aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa
    48961 gaattactgg ctaaagacac agatatccga gtgacttctt atgccagctt aagacaggat
    49021 ctagctaatt atcagtcgca aaaaattgat tatttgattc ttgatgaggc acaaatggtc
    49081 aaaaatagca gtacgaaaac tgcacaagca ttgagagaat tagctgtacc tcagcggttt
    49141 gcactgagtg ggacaccaat cgagaataat ttagaagaat tgtggtcatt gtttgcaacg
    49201 attatgccag gatttttccc gactaaaaca aaattcaggg aacttgccgc agaagaaatt
    49261 gcgcaaatga ttcgaccgtt tattttacgg cgagataaac aaactgtgtt gaaagacttg
    49321 ccggaaaaaa cagagatgaa tctatattct gcacttacag aagaacaaaa aactgtttat
    49381 ttagcttact tgcgtcaaat gcgtgaagaa atcacatcaa tggattctga agcattcaag
    49441 aaaaaccgga tcgggatact tgctggtctg acaagactgc gacaaatttg ctgcgatcct
    49501 cgtctgttta ttgaagatta ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta
    49561 ctggtagctg ccaaagagaa caaacgaaga gttttgctgt tttctcaatt tacagggatg
    49621 ctgactatct tgcaagaaga gttagccgag ctagggatct cgacatttta tttaagaggc
    49681 agtacgaaac cacaagatcg gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat
    49741 gtttttctga tttccttaaa ggctggggga actggattga atctcacggg agcagatacg
    49801 gtcatcttgt atgacctttg gtggaatcct gccattgaag aacaagctgc tggacgtgca
    49861 catcggatcg gacaaaaaaa tgtggtagaa gtgtggcgta tgatctctga aggaacgatt
    49921 gaggaacgca tggattcact ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa
    49981 ggtaatgaag aacagttgac gaaactgact gaagaagaca tccgcatgat tttaagtgta
    50041 ggagaaatcg aggagtaaga gactcgaaaa agcgttcagt aatgggtaag aaagcctttc
    50101 taaagaagcg attgtttatt tgatttaaaa aatagcaagg aggctgggat tccattttat
    50161 cccagcttcc ttgctatcat ttttttattt ctatttttaa aggttataca aagattgtct
    50221 tcattgtctc taacagctga tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt
    50281 caattttgcg ttctcgatgg ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta
    50341 gaacatcatt gtcgtaatta tcgccaacgt ataaggtctc ttctggaagc atatgaaatt
    50401 ctttctcagc cagctgaaaa atctcttttt ctggtttttg gaaacctgtt gcttgagaaa
    50461 tgagcatatt gcgggaagga atccaattgt tcaattgaag ttgcttcagt ttttttgtct
    50521 gatggtcagt cggcccattt gtgataattc ctaatgggac attcttttcc ttcaagaaat
    50581 cgagggtttt tttgacctcc tcatgcaagc agatattatc aagttcttcc tcgtaaattt
    50641 tttgaaataa gaggccatct tcttccgtaa tatgagggta gtctaaatct tttagtgatt
    50701 ggctgatccg atgtgctcgc atatattcta gtgtccaatc tcctgccatt acttttggga
    50761 agttttcatc actatgatgg cggaaccgga tatatagtgg atgcatatct gcatctgaaa
    50821 caagcggaac gactcttttg accgcgtttc gaaatggctg ctgctgatca tacatcgtat
    50881 catcaacatc aaacacaact gatttaatca aaattttaca cgcctttcgg ttttcattga
    50941 ttttttcaca aatccttgac tattgtaaca gaaaaaattg tctaaaaaag ctgataaata
    51001 aaggtttttc ttactatatt tctatttcct tgacagaata aggtttttat atttcagttt
    51061 ttttcactaa aaatcgtgaa acacgtcaat aagtttgatg aacaaattaa tcattatggt
    51121 agaagtcgat tgatttattt taatgcaatc tctgtggaat tttcgaaaga tttatttttt
    51181 taatacagtc tcaatataac tattcaaaca taaaataacg ttatttgatt tatttgttta
    51241 tagtaaattt tatttagtaa t
//
LOCUS       DAZKCW010000017        50159 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000017 DAZKCW010000000
VERSION     DAZKCW010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.017"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(39..350)
                     /locus_tag="ACG84Z_001049"
     CDS             complement(39..350)
                     /locus_tag="ACG84Z_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFP9161906.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(352..549)
                     /locus_tag="ACG84Z_001050"
     CDS             complement(352..549)
                     /locus_tag="ACG84Z_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFP9161907.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(943..2670)
                     /locus_tag="ACG84Z_001051"
     CDS             complement(943..2670)
                     /locus_tag="ACG84Z_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFP9161908.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2663..3856)
                     /locus_tag="ACG84Z_001052"
     CDS             complement(2663..3856)
                     /locus_tag="ACG84Z_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFP9161909.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4043..4687)
                     /locus_tag="ACG84Z_001053"
     CDS             complement(4043..4687)
                     /locus_tag="ACG84Z_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9161910.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQAKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4781..4915)
                     /locus_tag="ACG84Z_001054"
     CDS             complement(4781..4915)
                     /locus_tag="ACG84Z_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFP9161911.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4917..7049)
                     /gene="feoB"
                     /locus_tag="ACG84Z_001055"
     CDS             complement(4917..7049)
                     /gene="feoB"
                     /locus_tag="ACG84Z_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFP9161912.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7046..7519)
                     /locus_tag="ACG84Z_001056"
     CDS             complement(7046..7519)
                     /locus_tag="ACG84Z_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFP9161913.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7920..8144
                     /gene="nrdH"
                     /locus_tag="ACG84Z_001057"
     CDS             7920..8144
                     /gene="nrdH"
                     /locus_tag="ACG84Z_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFP9161914.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8303..10462
                     /gene="nrdE"
                     /locus_tag="ACG84Z_001058"
     CDS             8303..10462
                     /gene="nrdE"
                     /locus_tag="ACG84Z_001058"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFP9161915.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10512..11477
                     /gene="nrdF"
                     /locus_tag="ACG84Z_001059"
     CDS             10512..11477
                     /gene="nrdF"
                     /locus_tag="ACG84Z_001059"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFP9161916.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11566..12705)
                     /locus_tag="ACG84Z_001060"
     CDS             complement(11566..12705)
                     /locus_tag="ACG84Z_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFP9161917.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13014..13727)
                     /locus_tag="ACG84Z_001061"
     CDS             complement(13014..13727)
                     /locus_tag="ACG84Z_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFP9161918.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13981..14682)
                     /gene="nagB"
                     /locus_tag="ACG84Z_001062"
     CDS             complement(13981..14682)
                     /gene="nagB"
                     /locus_tag="ACG84Z_001062"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFP9161919.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14916..16448
                     /locus_tag="ACG84Z_001063"
     CDS             14916..16448
                     /locus_tag="ACG84Z_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFP9161920.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16639..17841)
                     /locus_tag="ACG84Z_001064"
     CDS             complement(16639..17841)
                     /locus_tag="ACG84Z_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9161921.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(17923..18612)
                     /locus_tag="ACG84Z_001065"
     CDS             complement(17923..18612)
                     /locus_tag="ACG84Z_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFP9161922.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18718..19086)
                     /gene="rplL"
                     /locus_tag="ACG84Z_001066"
     CDS             complement(18718..19086)
                     /gene="rplL"
                     /locus_tag="ACG84Z_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFP9161923.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(19139..19642)
                     /gene="rplJ"
                     /locus_tag="ACG84Z_001067"
     CDS             complement(19139..19642)
                     /gene="rplJ"
                     /locus_tag="ACG84Z_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFP9161924.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(19846..19973)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(20052..20741)
                     /gene="rplA"
                     /locus_tag="ACG84Z_001068"
     CDS             complement(20052..20741)
                     /gene="rplA"
                     /locus_tag="ACG84Z_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFP9161925.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20845..21267)
                     /gene="rplK"
                     /locus_tag="ACG84Z_001069"
     CDS             complement(20845..21267)
                     /gene="rplK"
                     /locus_tag="ACG84Z_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFP9161926.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            21610..22278
                     /gene="sdaAB"
                     /locus_tag="ACG84Z_001070"
     CDS             21610..22278
                     /gene="sdaAB"
                     /locus_tag="ACG84Z_001070"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFP9161927.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            22291..23163
                     /gene="sdaAA"
                     /locus_tag="ACG84Z_001071"
     CDS             22291..23163
                     /gene="sdaAA"
                     /locus_tag="ACG84Z_001071"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFP9161928.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(23254..24354)
                     /locus_tag="ACG84Z_001072"
                     /pseudo
     CDS             complement(23254..24354)
                     /locus_tag="ACG84Z_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(24446..25333)
                     /locus_tag="ACG84Z_001073"
     CDS             complement(24446..25333)
                     /locus_tag="ACG84Z_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFP9161929.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(25410..25955)
                     /gene="nusG"
                     /locus_tag="ACG84Z_001074"
     CDS             complement(25410..25955)
                     /gene="nusG"
                     /locus_tag="ACG84Z_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFP9161930.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(26056..26226)
                     /gene="secE"
                     /locus_tag="ACG84Z_001075"
     CDS             complement(26056..26226)
                     /gene="secE"
                     /locus_tag="ACG84Z_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFP9161931.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(26250..26402)
                     /gene="rpmG"
                     /locus_tag="ACG84Z_001076"
     CDS             complement(26250..26402)
                     /gene="rpmG"
                     /locus_tag="ACG84Z_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFP9161932.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            26564..27208
                     /gene="cbpA"
                     /locus_tag="ACG84Z_001077"
     CDS             26564..27208
                     /gene="cbpA"
                     /locus_tag="ACG84Z_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFP9161933.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(27264..27767)
                     /locus_tag="ACG84Z_001078"
     CDS             complement(27264..27767)
                     /locus_tag="ACG84Z_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFP9161934.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27780..27826)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            28364..29329
                     /locus_tag="ACG84Z_001079"
     CDS             28364..29329
                     /locus_tag="ACG84Z_001079"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFP9161935.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(29428..30600)
                     /locus_tag="ACG84Z_001080"
     CDS             complement(29428..30600)
                     /locus_tag="ACG84Z_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9161936.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(30587..31732)
                     /locus_tag="ACG84Z_001081"
     CDS             complement(30587..31732)
                     /locus_tag="ACG84Z_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9161937.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(31746..32670)
                     /locus_tag="ACG84Z_001082"
                     /pseudo
     CDS             complement(31746..32670)
                     /locus_tag="ACG84Z_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            32787..33866
                     /locus_tag="ACG84Z_001083"
     CDS             32787..33866
                     /locus_tag="ACG84Z_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFP9161938.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            33863..34491
                     /locus_tag="ACG84Z_001084"
                     /pseudo
     CDS             33863..34491
                     /locus_tag="ACG84Z_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(34601..34828)
                     /locus_tag="ACG84Z_001085"
     CDS             complement(34601..34828)
                     /locus_tag="ACG84Z_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9161939.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(34931..37519)
                     /locus_tag="ACG84Z_001086"
     CDS             complement(34931..37519)
                     /locus_tag="ACG84Z_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFP9161940.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(37539..38198)
                     /locus_tag="ACG84Z_001087"
     CDS             complement(37539..38198)
                     /locus_tag="ACG84Z_001087"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFP9161941.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(38247..38750)
                     /gene="trmL"
                     /locus_tag="ACG84Z_001088"
     CDS             complement(38247..38750)
                     /gene="trmL"
                     /locus_tag="ACG84Z_001088"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFP9161942.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(38971..39837)
                     /locus_tag="ACG84Z_001089"
     CDS             complement(38971..39837)
                     /locus_tag="ACG84Z_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFP9161943.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            39946..40587
                     /locus_tag="ACG84Z_001090"
     CDS             39946..40587
                     /locus_tag="ACG84Z_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFP9161944.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(40649..42010)
                     /gene="mgtE"
                     /locus_tag="ACG84Z_001091"
     CDS             complement(40649..42010)
                     /gene="mgtE"
                     /locus_tag="ACG84Z_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFP9161945.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(42028..42927)
                     /locus_tag="ACG84Z_001092"
     CDS             complement(42028..42927)
                     /locus_tag="ACG84Z_001092"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFP9161946.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(42929..43726)
                     /locus_tag="ACG84Z_001093"
     CDS             complement(42929..43726)
                     /locus_tag="ACG84Z_001093"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFP9161947.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(43704..44408)
                     /locus_tag="ACG84Z_001094"
     CDS             complement(43704..44408)
                     /locus_tag="ACG84Z_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFP9161948.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            44539..45114
                     /locus_tag="ACG84Z_001095"
     CDS             44539..45114
                     /locus_tag="ACG84Z_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFP9161949.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            45232..45909
                     /locus_tag="ACG84Z_001096"
     CDS             45232..45909
                     /locus_tag="ACG84Z_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFP9161950.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(45988..47796)
                     /gene="pepF"
                     /locus_tag="ACG84Z_001097"
     CDS             complement(45988..47796)
                     /gene="pepF"
                     /locus_tag="ACG84Z_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFP9161951.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(47972..48970)
                     /locus_tag="ACG84Z_001098"
     CDS             complement(47972..48970)
                     /locus_tag="ACG84Z_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFP9161952.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(49196..49849)
                     /locus_tag="ACG84Z_001099"
     CDS             complement(49196..49849)
                     /locus_tag="ACG84Z_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFP9161953.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        15025 a        10514 c         8786 g        15834 t
ORIGIN      
        1 caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga tttatctcca
       61 taatctgctc gatataaacc atttattcca gcagttcttc caatttcact caaatttctt
      121 attaattcct cttgatattc agtgaatctt attttattag tataagcagt aaaatataga
      181 taattcacca atctatttat taaaggaccg ggatctaatt catatttttg tttttctaat
      241 tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc tttacttata
      301 gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat tttagcactt
      361 ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac aagtagttgc
      421 cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc cataatattt
      481 tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca aaatttttaa
      541 atgtttcata atctaatcac ccctaaatta atgtttttag actattattc taacattcat
      601 taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga ataagaattt
      661 aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga atgcacttcg
      721 tacataataa actttaatca cattagtctt tcatacctac gatcgatctc tttgactcgc
      781 acccataaat tcataatagt ttgtcggcgt ctttggacgt ttcgaagatg agctacgcat
      841 tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa tttggatatt
      901 tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt tccagctttc
      961 gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat cttttccatt
     1021 gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat tgtctaatac
     1081 tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat ggatctgctc
     1141 ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt tggcaaacat
     1201 ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg cttgacctag
     1261 tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca agttgtcata
     1321 tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga ttcctatgat
     1381 tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt aggctggcac
     1441 tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt gatctttata
     1501 ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg catctgactc
     1561 gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg ttacatcata
     1621 gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg tatcccattc
     1681 aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc ctataccaat
     1741 cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt ttttactttt
     1801 ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct gtgtaaaacg
     1861 gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat tcccgacttg
     1921 tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga tcatagaggc
     1981 aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca tgatcgtact
     2041 tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc cgaatgaatc
     2101 agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa aacgaacggt
     2161 tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga taccgaaaaa
     2221 tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt caaggatcgg
     2281 tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg gtaccccaat
     2341 gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca aatcattcca
     2401 tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa gtcctggacg
     2461 tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag gagctggaat
     2521 cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt gtaaaaatga
     2581 aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc agtttgccac
     2641 tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt tctgctaatg
     2701 cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct acaactgcaa
     2761 gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg tctttcccaa
     2821 tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc ctagcttcta
     2881 acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca gccatcagca
     2941 tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca gattcgatat
     3001 tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa cgatcgactt
     3061 cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct tcacctgttc
     3121 cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc cgtaaagctt
     3181 cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc aggtccagta
     3241 attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct tcgtccatca
     3301 gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt tgcatcccac
     3361 cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt tctaatgctt
     3421 tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac ccgtattctg
     3481 tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc atattgattt
     3541 tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct tctccatcaa
     3601 tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc aatgtggatt
     3661 tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg tcaaaattca
     3721 cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc ggctggtgat
     3781 cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt aaatgtttta
     3841 cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc tttctgaaaa
     3901 aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa gaaatttgct
     3961 tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag ccaagttaat
     4021 atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa aaaaagtttg
     4081 tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct gccgtaaatt
     4141 tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg ataactgtgg
     4201 cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc attgcttttt
     4261 ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc ttcgcttgat
     4321 tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc ttctccacac
     4381 ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat tgcaatagga
     4441 aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt acttccatga
     4501 ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa gcattgtacg
     4561 tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg ttttcaacga
     4621 tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt tttttctttc
     4681 cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg ctctagcaaa
     4741 ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg atctgttcct
     4801 tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt aaacgagtat
     4861 agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc gccatcctat
     4921 tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg ctgacggaac
     4981 aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa cgctacctgt
     5041 ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata agctaaaccg
     5101 cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg atggatagcc
     5161 ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga ataagctgct
     5221 gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc ggatacttcc
     5281 gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac caatcctgta
     5341 atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac aactgccagg
     5401 attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc ataaaaatta
     5461 taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc tgctttttta
     5521 acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg aggaaaatga
     5581 tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg tgtttttttc
     5641 aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga aggagctacc
     5701 caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa ctttgcagaa
     5761 caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt ttcaatcgtg
     5821 cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg aatgaaggat
     5881 tttcctgaaa gaccgaattt cctgaaaagt cgatccatga caaaagcgat cctcgccata
     5941 tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg cggtagaaat
     6001 cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg catccatccc
     6061 gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt accaaacaat
     6121 gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag ataatagatc
     6181 agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc aatctgatcg
     6241 attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag tgtacatagt
     6301 tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc gtccaatagt
     6361 ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc tatctcgtaa
     6421 tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg tttcttgccg
     6481 ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg tggatcatat
     6541 gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt ttcgattagt
     6601 ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc aagaccatag
     6661 gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat catattcaga
     6721 ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag atttcgttct
     6781 aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac caaataatct
     6841 cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg taggtcctga
     6901 atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt tacgcccggc
     6961 caattcccta catattgatt cgaaccagtc aagagattga acaagctagt tttcccgctg
     7021 tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc aagattagtt
     7081 cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg attggatctc
     7141 ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc atatccatta
     7201 accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc tctcctgctt
     7261 ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg acaaagattt
     7321 gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa atggcattgt
     7381 tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata ttttgcaaat
     7441 ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa ttctgctttg
     7501 cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt attaaaatca
     7561 ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc attctcacat
     7621 agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag cgaatcttta
     7681 gtattgatag ataaaaatga gaaaaaaata tttcttcata gttttccaca attttttctc
     7741 tattaaattt gctattttcc cacacgatac ttgttttcag ctcttttttc aaaaacacaa
     7801 aacttagtat tccacagttt ccacaacaca atatgtagtg tttgttgttt gactttttta
     7861 ctaagagttt tatactatct attatagata ataagaatgt gttagaggag gcactcacca
     7921 tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg taagatggtc aaacggtttt
     7981 taacagaaaa tcaaattgct tttgaagaag tcaatatcga tgaacagcct gaagcagtag
     8041 actggttgaa agcacaagga ttccaaagtg ttcctgtcat tacttctgat gcagaaacag
     8101 ttatcggatt ccgtcctgat cagttgcgta aacttgccag ctaacatgac taaaagaatc
     8161 aaaacgtgat acatggattt gaagggcttg agacagcacc agtttttgtc gcaaacttcc
     8221 aaatcctttt ttaaagctta aaaacaatgc aatgatttgc aatcaagcat catcaaatac
     8281 gaaatgaagg ttgggcgtac gtatgagtct taaaaattta caagatgtca gttatttcaa
     8341 gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata aggataaaga
     8401 agctttagtt gccttttttg aggaaaatgt caaaccaaat acgatgactt ttctatctat
     8461 tatggaaaaa atcaattact tgatcgatca agaatatata gaagcagaat tcattcaatt
     8521 gtattcacca tcatttattg aaaagctata tcaatttttg gacgagcaac atttttcttt
     8581 caaatctttt atggctgctt acaaatttta ttctcaatat gcgttgaaaa ccaacgacgg
     8641 ttccgcttat ctggaaactt atgaagatcg agtagccttc aatgcgcttt actttgcgaa
     8701 cggggatgaa gaattagcac ttgctcttgc agacgaaatg atccatcaac gatatcagcc
     8761 agctacacct tctttcttga atgctggacg taaacgtcgg ggcgaattgg tgtcttgttt
     8821 cttgactcaa gtcactgacg atatgaactc tatcgggcgc tcaatcaact ctgctttgca
     8881 attgtcccgt attggtggcg gcgtagggat tactttatca aatcttcgtg aagccggcgc
     8941 tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga aattattcga
     9001 agatagtttc agctattcta atcaattagg tcagcgtcaa ggagctggcg tggtttattt
     9061 gaacgttttc catccagaca ttattgcttt cctttcagca aaaaaagaaa atgcagatga
     9121 aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta cctgataaat tttatgaatt
     9181 gacacgtaaa aacgaagata tgtatttatt tagtccatat agtgtcgaaa aagaatatgg
     9241 tgtcccattc tcttatgtaa atattacagc tgagtatgat catctagttg caaatccaaa
     9301 cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa aattacaaca
     9361 agaatctggc tatccttacg taatcaatat tgatacagcg aaccgcgaga atccaatcga
     9421 tggcaagatc atcatgagta atttatgttc agagatttta caagttcaaa cgccttctgt
     9481 gattaacggc aaacaggaat atgaagtatt aggaacggat atctcatgta acttaggctc
     9541 gacaaatatc gtgaatttga tgcaaagccc taactttggt caatctgtgc gtacgatgac
     9601 tcgtgcattg acatttatta cagatgcatc tgatatcgat gtcgtaccac cgatccaaaa
     9661 cggaaataag ctgaatcata cgattggatt aggtgccatg ggcttacaca cttatcttgc
     9721 aaaagaacaa atggaatatg gctcagagga ttcattagac tttacaaata tttacttcat
     9781 gctgttgaat tattggacac ttgttgaaag caacaatatc gctcgtgaaa gaaaacaagt
     9841 tttccataat tttgaaaaat cagcttatgc tgacggcact tatttcgaaa aatacgtaac
     9901 tggagaattc cagccaaaat cagaaaaagt caaagcattg tttgaaggca tttttatccc
     9961 aactgctgaa gattggaatg ctttgaaaca agcagtaatg aaagatggac tgtatcatca
    10021 aaatcgcttg gcagtagcac caaatggctc aatttcatat atcaacgata cgagtgcaag
    10081 tattcatcct atcactcgca tgatcgaaga acgccaagag aagaaaatcg gtaaaattta
    10141 ttacccagcg ccttatctat ccaatgagac gattccgtat tacacttctg cttatgatat
    10201 ggacatgcgt aaagtaatcg atgtttatgc aatggcacaa caacacgtcg atcaaggcat
    10261 gagtttgact ttattcatgc gttctgaaat cccagaaggc atttatgaat ggaagacaac
    10321 aacgaagcaa acgacacgtg atttgaatat tttaagacat tacgctttcc acaaaggaat
    10381 caaatccatt tattacgtac gtacctttac tgatgatgca gaagaaatcg gaagcaatca
    10441 atgtgaaagc tgcgtgatct aatatcatag atagattcgc ttattcatat tttaattaaa
    10501 ggagcattct catgtcagaa acatattatg aagcaataaa ctggaatgaa attgaagata
    10561 tcattgataa atccacttgg gagaagctga cagagcaatt ttggctagat acacgtatcc
    10621 cactttcaaa tgacctagat gattggcgta cattgtctca attggaaaaa gatacagtag
    10681 gacatgtatt tggcggtttg acactgctag atactgtcca atctgaaagt ggcatggatc
    10741 agttgcgtaa agatgtccgc actccccatg aagaagccgt tttgaacaat attcaattca
    10801 tggaatccgt tcatgccaaa agttattctt ctatttttag tacactgaat acgaaaaaag
    10861 aaatcgaaga aatttttgac tggacaaata cgaatcctta tctgcaaaaa aaagctgagc
    10921 gtatcaatga aatctacaaa cacggtacac cgctagaaaa gaaaattgcc agcgtctttt
    10981 tagaaacatt cttgttctat tcaggttttt atactcctct ttattattta ggaaacaaca
    11041 aattggctaa cgtagcagag atcatcaaac taatcatccg agatgaatct gtacatggaa
    11101 cctacatcgg ttacaaattc caattaggat tcaacgagtt acctgaagca gaacaagaaa
    11161 cgttaaaaga ctggatgtac aatcttcttt atgagcttta cgaaaacgaa gaacgttata
    11221 cagaagaatt atacgatcca atcggctgga cagaagaagt caagacattc ctacgctata
    11281 atgccaacaa agcattgatg aacctaggga tggatccact ctttccagat actgccaatg
    11341 atgtcaaccc aatcgtaatg aacgggattt caacaggcac aagcaaccat gacttcttct
    11401 cacaagtcgg aaacggctat ttgttaggtc atgtagaagc gatgaaagac gacgattatt
    11461 tgattggatt ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa taaaaagagt
    11521 ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt cacttgtttc
    11581 ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc tcaataaata
    11641 gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta tgcaaatcag
    11701 catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga tcgtcaaagg
    11761 atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat ctaattgttg
    11821 gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa acaaaccgac
    11881 aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat tcgtgattcc
    11941 gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg ccaaaaagct
    12001 cattacacca ataatcaaag catctaagat cgtactgctg atataggcag ataatgtttc
    12061 gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa agaagtgaga
    12121 caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa atggaacggt
    12181 aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac ttgcagataa
    12241 actgactaat atgatattga acaaattact aagagataaa tttgctgatg ctaattgttc
    12301 ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc atttgcttgt
    12361 ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca ttaactgagg
    12421 cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg tcaataaaaa
    12481 accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat cgaacatata
    12541 atagataaaa ccagcaacaa gcaatggtaa aaaaactgcc gaaagcattt tcaatattgg
    12601 actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga gtactagctc
    12661 cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc tcctccaagg
    12721 tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat tttcatttgc
    12781 ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt aaacaaaaac
    12841 acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata aacggtgttc
    12901 aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa ctatttttat
    12961 ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat catttattgc
    13021 gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc ctcgatcaca
    13081 tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta cactcggtag
    13141 tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt ctcttcaaaa
    13201 taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc taacttttta
    13261 gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat cccgataaaa
    13321 ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc agcaattgcc
    13381 cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat gatcgttccc
    13441 gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc atctgaacga
    13501 atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact agcgatctca
    13561 acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt acgcatacct
    13621 gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag catagcgatc
    13681 cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta aacaccctcc
    13741 agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt acctcttacg
    13801 aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac ggtgttcaat
    13861 cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt tttcctttgt
    13921 cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta ctattgaaaa
    13981 ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt gattttgcaa
    14041 tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga ttgcatcagc
    14101 tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg aaccgattcc
    14161 cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt tgtttgcatt
    14221 gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag caccaggttc
    14281 attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga ttggatgtgc
    14341 atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt ttccatctgg
    14401 tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga aatgacggta
    14461 gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag aagtcatttc
    14521 actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg tgcttcctgt
    14581 tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt caaatgcttt
    14641 ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg ctcctttata
    14701 ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta gtatagacca
    14761 aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt ttcataagat
    14821 ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact gtggacgctt
    14881 tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca ttaaacaaca
    14941 ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa ttaaatgctg
    15001 gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg attaaaatca
    15061 tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat attcacaaag
    15121 gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa tttctaaaaa
    15181 ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac caaacatata
    15241 gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg gaattagacc
    15301 aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg ttggggatcg
    15361 atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt tcaaaggtga
    15421 ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa ccaaccaatc
    15481 acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt gacggtgcgt
    15541 atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat atcgcagaca
    15601 tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg aaacaaaagg
    15661 aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa atcgaaaaga
    15721 ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca aaaagccgac
    15781 aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt aaagctgtct
    15841 ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact gatttagtca
    15901 tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt ggtgaaaata
    15961 ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca ctgatcggtg
    16021 agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc aattactttt
    16081 cacaagatct gtactgggaa aatccattag aaacaccact acaatattta agcagtcaat
    16141 ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg ttagttaatc
    16201 aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag gtgaaacttg
    16261 cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg aaccatatcg
    16321 atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga acagtaatca
    16381 tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt gagattgaac
    16441 caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag ttttgtcaca
    16501 actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag ctcaaaaaac
    16561 ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc agaacagctt
    16621 ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt taaaaacaac
    16681 tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta cacctaacca
    16741 gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc caataaagta
    16801 cataaacata aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg
    16861 tgtttgattg gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag
    16921 caaaatggcc aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac
    16981 aagtcccata tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg
    17041 tgcagcaact gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca
    17101 attgtaggcg ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc
    17161 aaacatgaaa aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg
    17221 cggcaaactt ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg
    17281 cggcattttc cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata
    17341 gatcatccgc caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat
    17401 ccccacgagt aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc
    17461 tagtaccgca ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa
    17521 agaagcgcat gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc
    17581 agataacgct gccattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac
    17641 taaaaacagt aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc
    17701 acttgtgcta acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat
    17761 attggcaaca acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg
    17821 ttttttttca ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg
    17881 aaaagattgg aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt
    17941 tccttgtttt ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac
    18001 acttgcaacc aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca
    18061 cgcatacaac acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag
    18121 aggcaatttc atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat
    18181 atagcctaac attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg
    18241 attcgtttcg gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat
    18301 gttaccaaga gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa
    18361 accagcaatg actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt
    18421 caatacgatc aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc
    18481 tgccttactc gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa
    18541 ccgatagccc actaccagta tcagaatgat tcccaacgag atcaatatca atcggattat
    18601 tttctttttc atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata
    18661 aaaacaaaaa agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta
    18721 tttaacagtt acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc
    18781 tttagatacg ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt
    18841 caagcctaaa ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc
    18901 tgcagttaat tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc
    18961 agctacagct acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag
    19021 gtcgttaagt tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa
    19081 tgccattata atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt
    19141 aagctgcatc tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga
    19201 ctggcgcttg tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg
    19261 ccaatgctgt gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt
    19321 ctaatgcttt tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt
    19381 cgttactgaa tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag
    19441 cttttttagc tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat
    19501 cacgaagttg tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga
    19561 ctactactga tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt
    19621 ttgcgataat tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt
    19681 tttgcactga aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca
    19741 cctattcact tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct
    19801 ttgctcaacc agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa
    19861 actctatgcc accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta
    19921 ggaaattaag gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact
    19981 agcttagcat gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt
    20041 ctaatattta attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg
    20101 atcgttacat ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca
    20161 tcatggattg ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt
    20221 ggtacatgga tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg
    20281 tttactgctt ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct
    20341 tttggtccta atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca
    20401 actacatcaa agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg
    20461 aaatctgcac cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca
    20521 gtttgtgttt taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct
    20581 tttttagggt ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg
    20641 tttgtttctt ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact
    20701 ttttttaatg catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg
    20761 tggttataac ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga
    20821 agctgctgtc ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc
    20881 ttcaaccatg cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc
    20941 agcgatttct cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc
    21001 tgaacctttt tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt
    21061 aacgaatgtg aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc
    21121 ttgatcagct gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg
    21181 acctagtgca ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt
    21241 aacgattttt tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta
    21301 attggagatg catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata
    21361 atgtgcaaaa caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt
    21421 tttctgctat ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa
    21481 tttttcgttc tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa
    21541 agcaaacaat aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag
    21601 gtggagaaaa tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg
    21661 attggtccaa gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt
    21721 atatttggcg aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc
    21781 tatcgggggc acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat
    21841 gatgaacgtt tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt
    21901 gttcctaaga gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga
    21961 acacgaaagc tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa
    22021 ttgaatggat tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa
    22081 gatgttccag gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc
    22141 ggcactatga cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta
    22201 gatgatcctc aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc
    22261 gtaaattatt tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat
    22321 caagcaaaag cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt
    22381 ggccgttccc gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa
    22441 tcaatcaacg agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca
    22501 aaaaaattag atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa
    22561 gctgtacgca atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct
    22621 acaccgactg ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg
    22681 cttgatttga cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta
    22741 gtcatcgcaa acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt
    22801 tctgcaagtg caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa
    22861 gcagcacaag cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt
    22921 gcaggcttag ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt
    22981 atctctgctg atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt
    23041 gctgcaatgt accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt
    23101 ggcttagctg ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg
    23161 tgataaagct ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa
    23221 gagaggacta attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac
    23281 ttcatcgatc gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg
    23341 ttcaaaaaca gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg
    23401 gccaatcgca actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg
    23461 gacaccagag tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa
    23521 tacttcaaag gacgcaggac ctccatctag ttgacgtcca ccatgattgg atacccagat
    23581 accatctgcc cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac
    23641 gataactgga agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg
    23701 ttttgcagct gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg
    23761 ttcgctatac gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc
    23821 ttcttcacgg taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc
    23881 ttctactgct ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg
    23941 gaaaaactgc ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata
    24001 agtgctgatg gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc
    24061 tttttcatgt gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc
    24121 aattccgaaa acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat
    24181 gattttcttt gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc
    24241 accgcgaata tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta
    24301 ggcaatgttt acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga
    24361 tccttctttc atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa
    24421 catttactct cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat
    24481 ctacttcttg gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt
    24541 cctctatttc atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg
    24601 gtactgttcc atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag
    24661 tggttatagg aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag
    24721 caggcccctt tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa
    24781 aaggcgcgcc aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg
    24841 ttcctaaata gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat
    24901 ctatgccgta gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc
    24961 actcgttatt tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag
    25021 acaaatctcc tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta
    25081 ctgcttgctg atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc
    25141 tgtagccgtg gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg
    25201 ccgttttttc tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta
    25261 acgcaaacaa actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga
    25321 ttggttctgt catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa
    25381 tcatatgatc gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca
    25441 agttctgtac tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct
    25501 ccgtcaactt ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg
    25561 acttcgccaa cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag
    25621 atatgattga cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca
    25681 acgaatcctg tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc
    25741 atttcaacaa gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt
    25801 ttgacttcag tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc
    25861 atactttgcg cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta
    25921 tgcaagacat accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa
    25981 ataaaaaaac ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac
    26041 gttgtggcta gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat
    26101 tacgtaaaac atcaatccga aaataataga agtttcgatg actactaacg tatctttacg
    26161 gagttgtttt ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa
    26221 tttcatgaga caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga
    26281 ttacaatatt tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact
    26341 gattttgtgt agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc
    26401 atttacttct gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact
    26461 ttttacttgt caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat
    26521 taatttgaaa ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact
    26581 tgtatataag aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt
    26641 aaaaatttta gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat
    26701 tttccgtgga aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat
    26761 gacgcttcct gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc
    26821 tttcttcaaa gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga
    26881 aaatcatttt tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg
    26941 gagcgtagaa caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt
    27001 ggctgctatt gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga
    27061 tatcgaaaaa gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc
    27121 gaaagtatgt gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat
    27181 tgaaaatttg caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg
    27241 ctttcttttt tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa
    27301 taatacatca atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca
    27361 taggttgtcc aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg
    27421 ctgatggtaa agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt
    27481 tgcaataaag ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc
    27541 atgataccaa aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc
    27601 aatttacggt taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc
    27661 cctgaggata caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca
    27721 tttacaacga ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt
    27781 ttctcctagt ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat
    27841 aattataaca gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag
    27901 cttaaacaat gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg
    27961 gtcataagaa ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga
    28021 aacttaaata aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct
    28081 agcaagcagc tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt
    28141 aatggatcat gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt
    28201 tcctagactt ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac
    28261 aagtttcttt cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag
    28321 gagtattaaa atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca
    28381 tatattgatc aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt
    28441 accggtatta aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca
    28501 cgatgctgag attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga
    28561 acagaaaaca atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca
    28621 tcaggtactt gatactttct atcagatgga agtagaattc ccagttgctt atattccagc
    28681 aggttctgga gatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact
    28741 tcagctgatt ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa
    28801 aataagtgaa aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat
    28861 cgtccatgcg acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc
    28921 attttcgtat ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct
    28981 ggtagatgca ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa
    29041 gcatcctttt tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt
    29101 cattgatttt gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt
    29161 acttatacag aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt
    29221 acgtatcgtt tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg
    29281 accttttgat atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt
    29341 ttgtcagaag ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt
    29401 tgtcacagtc ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata
    29461 gtttctttct ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa
    29521 gacacaacca ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact
    29581 gatcaagtta ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac
    29641 catttctggc aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat
    29701 aaaaatatct ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc
    29761 cgaaaagcta atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt
    29821 tatatcccac gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa
    29881 cagcagcgag taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat
    29941 gggcgcactc tggtttcgtt tactgatctc tttgcgatta aatgctagat tgatgacgct
    30001 gaaaccgcta aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt
    30061 caacagcttt ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga
    30121 gagtgccatt tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag
    30181 aatcagtgtt tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc
    30241 tgggcgactc tgtatcttga tcgtcggcat ctttcctact tcgacttgtt cggtaaagtc
    30301 tgcaggcaga tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt
    30361 ttgtgaggtt ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc
    30421 atcgactaca ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt
    30481 attttcaaca tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc
    30541 tatcagtaaa ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat
    30601 aacgcacccc tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca
    30661 accatagaag attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac
    30721 tttcgctgat caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc
    30781 aatacttcac ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg
    30841 aaatcaagat gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg
    30901 tacctaacaa aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac
    30961 gttcaccaaa gtctacttga tagataaaac gaaagacagc taacataata taaatctctg
    31021 tcaaaacaat cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag
    31081 gaatcaagga caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc
    31141 ggacccccca catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac
    31201 ttttgaaact catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa
    31261 cagtcatgat gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac
    31321 caatacgctg taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt
    31381 gacccacatg gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg
    31441 catttagctt ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat
    31501 cattgacttc gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg
    31561 ctttgattac aattccagta ttaatcgttt cgagattgcc accttgatca atctcgccaa
    31621 aggccgccat aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg
    31681 atttatttcg cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc
    31741 ctcctctagt ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct
    31801 tctttggttg ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc
    31861 aacaatactg tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt
    31921 ccatcagaag ctattgttcg ctgacaacac gttttctggg agtaatggga tgtcgatcgt
    31981 caaacgatcc gccgtccgta ccatatcttt tagagattct ttggttcctt tagcaatcac
    32041 ctgtccttga tccatgatca cgatctggtc gcaaagaatt tctacttctt ccatgtaatg
    32101 tgttgtatag acaatggttg ctccttgtcg attcagctcc ttgatacttt ctaaaatttt
    32161 attccgactt tgggggtcta cagctactgt cggctcatct aaaaaaatta accgcggctt
    32221 gtgggcaatc ccacatgcga tgttcaaccg acgtttcaag ccaccactaa gttctcctgg
    32281 acgaaacgaa acatattttt ctaatcccac taattgaatc acctcttcaa tcaaggcttt
    32341 ccttttctct ttttcggaaa catataaacc gcaaaaataa tcgatatttt cttgcacact
    32401 tagttcgtca aagaccgcaa cgtcttgagg aacgacccca atcattgcct tgacagcata
    32461 attttcagga gtcattgttg tcccgaacaa tttaatggtt cctttgtcat aatttaacaa
    32521 agaaagcata cagttgatgg cagtcgattt cccactgccg tttggtccta acagacctaa
    32581 gacttctcct tcttgtactt gcagatcaaa atgattcaat gctacaaaat ctccatagcg
    32641 tttgactaat ttatcaattt cgataatcat catgaaaaac tccttccaaa tttcttgttg
    32701 atctgactat aataaagtgc aagaaaagaa actagtgacg attggctaaa ccacacatga
    32761 catttgtcac aatgaaggag tctgctatgc ataaatctcg gctactcaac gaaactagct
    32821 ttctactggt tatctcattg cttttgctgg taagtcaagg attcgttgct atgcaagtta
    32881 tctatttatt gatcgccgtt ttattcactg gtgtcagtta tttactgcct acaaagccaa
    32941 attggatttt ccaagttatt ctatttcttt tatgtgcctt tttacctgat cttgtcctgt
    33001 ttctgccagc gacgatgcga gtgatcgccc ctgaagaaag ccaccttgat tacttgtttt
    33061 tgttaggttt tttgttgatt tcgacggttg gtaatcatcc ccccatcaag gtcgcctttg
    33121 tcgtaatttt gctgtttttt tccttttact tacgaaaaaa agatcaacga acgaccgatc
    33181 ttgagaaaaa gtacattgtc tccaaagata ctcattggga aaaacaacaa gagttatcgg
    33241 aacaaaataa agcattggcc ctgtcacaag aaacacaatt agccttgcaa attgtggaag
    33301 aacggaaccg aattgcccga gacatccatg acaatgtcgg tcatctgctg tcaagtgcga
    33361 ttttacaaat tggtgcgctt gaaatgatca atcaagaacc aaaactaaaa gaaccattag
    33421 aaaatttaag tgccaccgtt cacactggga tggatcggat tcgtcaaagt gtccatgacc
    33481 tccatgagac atcgatctct tttcaacact ccttagagtt tctgatcgct gattttcctt
    33541 cttctgttac gattgaagga aacttgtttg aaggattgaa tgaaacgcag caaaactgct
    33601 tcttaatggt catcaaagaa gccttaacca acagtatcaa acatagtcat gccaaaaccg
    33661 ttgttttaca ttttcgaacg ttgccggcct tttatcgctt gcaaatcacg aatgatggca
    33721 ccagcccaca aaaaaattct gctcccggta ttggtttgaa aacgatgcgt caacgtgttc
    33781 aagaacaaaa gggacaagtc catattttcc aagaaaacca gcaatttcag ttaacgatca
    33841 ttttaccaag ggagggacac caatgataac agtagtcatt attgagatga tccatttgtg
    33901 acgaaatcgt tacaaaccat tttagaaagc acgaaagaga tccgtgtgtt aggcattggt
    33961 cattgtgcca aggatgcgct agtcttatac gaaacccatc gtcccgatgt tttgctgacg
    34021 gacatccgca tgcctaaaca aacgggcatc gatgctgcca aagaaatttt ggctaaattt
    34081 cccaaagcca tccttttgct tttgacgaca ttcaaagatg aagaatacat ccgcgaagca
    34141 ttttccatcg gtgtcaaagg gtatttaatc aaacagaact tgcaagcgat tattccttct
    34201 gtcaaatccg cttataatgg acaggccgta tttggtaatg aaatcatcga gactttcact
    34261 caaatgatga agaataaacc gacgattgat agtcatgctt atgcttcttt tagtgaacgt
    34321 gagcttgcaa tcatcaaaga agtagctgcc gggaaaaaca ataaagaaat tgcagatgcc
    34381 ttgtacttga gtgacggcac tgttcgcaat tacatcagcc aattactaga aaagctagat
    34441 ttacgggatc gcacgcaatt ggctatctat ttttatcagc atttgcaata agtcttatct
    34501 aacacaaaaa aacctgaatg atgctccttc gcatcattca ggtttttttc acatcttcta
    34561 ttcaattgtc ccgcaaacca tttcctcacg attgaaagaa tcaaggattc gcagggctgc
    34621 caggattcgt tggattgttc ggcgtgttag gcggaaaaat aggcgccttg tctaacgttt
    34681 tttctagttt tgattcttca cgatcgtctc gttctacatc aggactttca ttcaatttga
    34741 attctttttc catctcatct aactttttaa agtcattgcc agattctttt gctaatttcg
    34801 ctaatttatc ttcggtttct ttagccataa agtaacgccc cccttttgat ttcagcttag
    34861 catatcacac tgaaaaaaca aaagaaaacg ctaaccaacg atcattttta gctatttctc
    34921 atctttaaaa tcaagcattt tttgccggta taaaatcgta gggagaactg ttttccatac
    34981 caatcatcgg atctactaac tggttatcga tcacttctgc tgtaagaacg aaatctttag
    35041 aaacagcagg ttctacctct tctttctttt cttctccaac aaatgaagaa aacagatctg
    35101 gttccactgt ttccattact tggtttttcg tttcattcgt cccactgtca tcttctacag
    35161 gtagcttttc ttttacaacc cgtggctctt ttgtatagtt cccatcttca aatggatcat
    35221 ttccgaccaa agaatcttca taagctgcta gtttggtccg gagagtgata ttcattttat
    35281 cattatccat gatccttgat ttcaacgtag tcatccggct tgctgattca ttcgctacac
    35341 aagtgacata ggcttgctct tcccctaaca aaatcaacag ttccttactg cgagtcactg
    35401 ccgtgtagag caaattacgc tgaagcatcc gctgatattg atggaccatg ggcaaaataa
    35461 ccatcttgaa ttcactgcct tgtgatttat ggattgagca acaataagaa agagtgattt
    35521 tattccattc gtttctttta taagtgacct catttgcatc aaactggata actaattcat
    35581 ccactttatc ttcagaatct tttgccaaga tgatacccgt gatttctccc atatctccat
    35641 tgaatacatt caattcggga gtattgacta attggaggac tttgtctcct atccgataaa
    35701 cggtgtcgtt ccaatgtact tccttttttc caggtttccc tggattgaat atctcctgca
    35761 tcattttatt taacgcatcg atccctgcag gtccccgata cattggtgct aatacttgga
    35821 tatcttgtgc acggaatccc ttatttttcg ctttttccac aattttagag atcaagggtt
    35881 caatttgata agcatcactt cggaaatagg aacgatcttt ttgattcttt gtgaaatctt
    35941 ttggcagacg tccttctttg atctcatggg caagaggaat aatactagaa ccatcacctt
    36001 gccgataaat ctgattgagt tccattttgg gaatttgttc gatttccaaa agatcatgga
    36061 gtacttgacc aggaccgaca gagggaagct gatctttgtc tcctactaag ataacttgca
    36121 tattcgtcgg aatcgctttg aataatgtgt tagccagcca tgtatcgacc atagacatct
    36181 catcaacaat caaaagtccg ccttctaatt ctttcgtact gactgaaggt gttttttccc
    36241 gtccattcag ccccagaaga cgatggatcg tactggcagg cagacctgtc gtttcgttca
    36301 ttcgtttagc tgctcggcca gttggtgctg caagtagaat aggaaaaatt tcttgggtat
    36361 attttgaagg atccaattcc agtccgttca actctgcaaa aagattgacg attccgttga
    36421 tcacagtagt tttccccgta cctggtcctc ctgttaaaat aaatagaggg gaacggattg
    36481 cttcagcgat agcttgttct tgcgaaggtc catactgtat gccgaatatt ttttcgatac
    36541 gccgaatatt cttctgcact tctttttcag gataatggat ttctttttta cgactgagaa
    36601 ggcgctggat cgaattaccg atcccccatt cagaaaagta caaactgttt tcgtaaagat
    36661 tagtctcttc ttgttgtatc tttccttctt caacaagttg gataattaca gtagcaacct
    36721 gatcaggctg gatttcaatt gggcgacttg tttctaaaat acggatcgtt tgctgaagca
    36781 atgtctccgc cggtacgtat gtatctcctg tttgaactgc atgctgaaaa atctgatgca
    36841 agatagctgc tcgaattctt ctcggtgaat ctgctgcaat accgatttgt tcggctagat
    36901 tatctgcacg tttgaacccg attccttcta tgtcttcgac tagctggtac ggattttctt
    36961 cgatgatatc caaagactcg ttcttatagg cctggtagat actgaaagct aactgactac
    37021 cgaacccgta acgattcagt cccatgatca cttgatccat cccgtggttt agccgaatcg
    37081 tctcagcaag catttctctt tttggcttcg tcaaaccgga gatttgtttt aataccgaag
    37141 gatcagcaat gattttttcg atagcatctt ctcccagcaa ttctacaatt ttttctgctg
    37201 ttttcttccc gattcctggg aatttttcgc tggaaagata cgctacgatc ccatttgcag
    37261 ttgttggctt ttcttgctca tatctttcga gtttaagctg ccttccgtat ttaggatgat
    37321 ccactaattc tccataaaaa cgataagtct cattttcttg aatatcgccg aaacttccgg
    37381 tgactacaat ctctttttca cggtaatcag ctgtggtttc actgatgtgt accaaaagca
    37441 ctttgtaaaa attactagga ttttgaaaaa aaatcgcggc aactgtacca acgaaataag
    37501 gcatttcttc tggctgcatc ggaagccgcc tccttcttct atagtaaagg ttctggtgct
    37561 gtttcagttc ctaaaaaatc tgtttggttc catactttca gttcatatgg caataatctg
    37621 caaggctctt cagtctctaa aatcgtcaaa ctactattga acaatccacc catttcacgc
    37681 aactcactta gctcttttcc tgtcatccat tgaatggctg cagttaaaga agctccatgt
    37741 cctacgaata aaagtgggcc atctttatgt tgggcaaccg catctgctac aacagtttcg
    37801 atacgtgtga ttgccgattc aatcgtttct ccgtgaaaag gagaaggatc atacagatct
    37861 aaatgattac gcaaattcgg cagattatcc ggatatttct ggtacatttc atcgatcgac
    37921 tgaccttcta aagtacccag ccctagttct cttagcttat ctgtataaaa aatctctacc
    37981 ggacgagcaa gctctttgtt gataccttct gctgtatcac gtgctcgctt tgctgtactg
    38041 gaataaattg ctttaaaagg aacatatttt acctttttcc caaatgcttt gatttcttcg
    38101 taactttgtg gcaaaagcgg agaatcgcca ttgctccctt gaaaacgtct ttcctgattc
    38161 cattgtgtct tcccatgtcg ggtaaaatat agttccatac gcagcaaact cctgtctttc
    38221 ttttatttta ctctataata aactgtctaa tccagcttgt cattttcata gtgatgcgtc
    38281 aattctaaat tagggaatcc ttgctggcga agtgcttcat acactatcat tgcagctgta
    38341 ttcgataaat tcaatgagcg gacatgctca tcattcatag ggatgcgtaa acacttttct
    38401 tcgttttcac gcataaatgt ttctggcaaa ccggttgttt cttttccaaa taaaaagaag
    38461 tgctcttctc catcagcaaa attttcgtca ctatatactt tatgggcaaa ttttgagatc
    38521 aaatgtagtt tacgattacc taaaaatgtt aaaaaagctt ctaaattact gtggtaagta
    38581 atatttacat cattccaata atccaaccct gcccgtttta gatgtttgtc atcagttgaa
    38641 aaacctagtg gctcgattaa atgaagcgga gtattcgtgg ctgcacacgt acgggcaata
    38701 tttccagtgt ttgcagggat taatggttca aataaaacga tatgattcat caggatcatt
    38761 cctctcatat ttatgttcgt ttctattttc tgacaatttg atttttgcat aaaaaaaaac
    38821 gtatcaactc ggtgtcagtc actgcgagtc gttacgttag tgaagctctt ctcactaact
    38881 tttatcagaa caggaacctg ataaaaacca atgaaaaaac aacttgttgc taatataaca
    38941 ccctcaactt ttttttgcaa cctctactca ttaaaaactg ctagaaaaac gttttctctt
    39001 agttcctttt aataattcta tgtcaattgt aatcttcttc aaaggattct tatataagtc
    39061 tgctttgatt cgctcttcta cctgccattc taaaggtgac atggccaaaa gatctttttg
    39121 attttcctct ggtatctcaa attcataggt tacacgctga cgttcagtta atttcattgc
    39181 ttcagcaaac ttggctacta cacgttcatt ggaataactc tgtttttcag gttgattcgg
    39241 ataaaaagcc tgacgtagtt cctttaaata attttcttgt ggcaccacct tcaacacttc
    39301 tccatcttct gagagtacac gttggaattc ttggtaatga gaaggcgaaa agatatttaa
    39361 aaccgcgttg aatgtttgat cagcaaacgg caaattggtc aaatcagcta cacaccaaaa
    39421 tgcttcggca gattgttctg tagctgcgta gactccttct tttgaaatat caaatccaac
    39481 agcattttga atctttttca attttgaaag ttcattcaag aagctacctt ctccgcagcc
    39541 aacatctaat agcgagactt cttcaggtaa atgctgcgca atagtctcaa taacgggctg
    39601 atacatgcca gattggatca ttctacgcct tggaacgaac attccttgat cgtattctgt
    39661 tttaaccgca tgggataaaa aataaagtgt tccttttttg gaaaggtcaa aacggtgatt
    39721 atttttgcat atcaagccat tatcagactt ttttacttct tcttggcaaa ccggacagcg
    39781 gaacagctga tgattttctg ccaaaaactg gcgtcctcgg tcaatttttt ttaacatagt
    39841 tccccctcat ttctgtttta tcttaccgtt agatgctcac tttggcaact gctaaaaata
    39901 tgatacaatg cctagaagaa agtgaaagat aaaggagaag attagatgat caaagaattt
    39961 tgcgctgaaa actacacatc tattcctcta gcaattgcta gaggagccga tcggatcgaa
    40021 ttgtgtgaca acttagcggt cggtggcaca accccgagta ctggtgtgat cgaagaaacg
    40081 ttaagttatg ctggggaaaa agatatcccc gtaatgacga ttattcgtcc tagagggggc
    40141 gacttcgtct ataacgatat cgaattgaaa atcatgcata ctgatttgat tgaagcaaag
    40201 aaattaggga cggatggcgt agtatttggt tgtcttactc cttcaggctg gctagacgaa
    40261 gaggccttag aactattgat cgaaacagca gaagggttgc agatcacctt ccatatggct
    40321 tttgacagta ttcctgaaga tcggcaattc gaagcaatcg attggctggt agaacatggt
    40381 gttgaccgta tcttgactca tggcggtcct gctgacaaaa ctattgtaga aaatttccca
    40441 cggcttaaag aattgattgc ctatacagat ggccgcttaa tcattttgcc tggtggtggt
    40501 gtcactgcag agaatgcagc acatgtagct aaagaattga acgtaagcga agtacacgga
    40561 accaaaatcg tggatcttca gttataatct tataaacaaa aaaacatttg caacaggcat
    40621 aatgcttatt gcaaatgttt ttgttttttt acataaaata gcccataaat aaagaagcaa
    40681 tattgaaata aatcagtaca ctcgtcaaat cgctcaaagt cgtgataaag ggaccgcttg
    40741 ctactgctgg atcaaatcct agacgatcca ttagcatcgg gattaaacta cctgcaagat
    40801 tcgccactgt gattgcaaat agcatagcca tccctatgac aaaccccaag ataaaattat
    40861 gtttccaaaa acctacgatt agaaaaatcg tgatccccgt aacagctcct gtgacaacgc
    40921 cggtcaagac ttcagccaaa acaagtcgaa caaatccatg atctttctca tcagaaatcg
    40981 caagtcgacg aacagccaca gctagcgact gggttccagc attaccggca gttcctgtaa
    41041 tcagcgaaat gaagactgct aaaatactcg cttcacttac caagtcttca tagtgactga
    41101 ttaaagaagc ggtcgacata cctaaaaaca acagagtgat cagccaaggc aaacgtcgag
    41161 acgctgcctt tactggattt tcattaattt cttccacatt gaccccggca agtcctgaat
    41221 aatcgctagc agcttcatca tcaataacgt cgatgatatc atcgactgtg acgattccta
    41281 acaaatgatc atcataatcg gtaacaggaa gagctaagaa gtcataatct ctaaatgttt
    41341 gtgccacatc ttcttggtcg tcgcctacat gaactgaaag cactcgttcg ctcatcagat
    41401 cagaaatcat tgcgtcgtca tcattcacga ttaggtcgcg cagagaaata acccctacta
    41461 gctgaccttc ttgattaacg acatagatgt aatagattgt ttcagctaca tctgcttcgt
    41521 tcttcagcac gtacatcgca gagcgaacag tttgattggc tacgatcgaa acaaattcag
    41581 ttgtcatgat cgcgccagcc gtttcatcct cgtaatggag aagttccttg atttcactgg
    41641 catcgtctgc cgacatcaaa cttaaatatt tagcaatttg ctttttatcc agcgtattaa
    41701 gcaagtcaac agcattatct gtatacatct cagaaagcat atcagctgca tagctaggac
    41761 gcatttcatc taggtattct ttcatatgtt cgttgtcttc ttcaatcaca tcgaacatat
    41821 ccgctaattc tttaggcgac agataggaat agatcagctg cctgttctct tctgtaagag
    41881 attggtagaa ttgcccctgc tcatagatat gcatctctaa aaaactgttt ctgaatgcct
    41941 gaatattatt ttcccttaaa tcttgagtca actgggcaaa tctttcctct aattcttgat
    42001 tttcatccaa accaatctca cctcgcctta ttcttcaaac cgtctcacaa ctgcctccat
    42061 gtctgcggct aaaggctgct tgaactccag caactcttct gtaaatggat ggtaaaaacg
    42121 cagatcataa caatgaaggg cttgtctttt tattcccaga tccattcgcc cgccatacat
    42181 atcatcaccg agcagggcac agccaattgc ggaaaaatga actcttattt gatgtgtcct
    42241 tcctgtatgc agctggatat caactaacgc gatttctgtt agtcgcttct ctatccagta
    42301 ctcagtctgt gccgaacgtc cttcatcaga gaccattcgc ttcaatagcg aagaataatc
    42361 tcgggcgatc ggcaaatcga tatgtccatg tgccgataaa tctgaaagcc ttccactgac
    42421 taaggcctga tattttttca caaacttctt ttcacgaagt tgcatatcta attttgcgtg
    42481 cgcaaatcca tgctttgcaa aaagcatcaa accagatgta tcccgatcta gtcgcgtcac
    42541 cacatggatt acttggtttt cgtaaccttg ttttttataa taagccttta cacgattagc
    42601 cattgtccca tttggatggt attgggcagg aatagacgaa acgcctgctg gtttatttac
    42661 taccagaacg tgttcatctt catacacgat atcgatcggt gtttcatcca aaagtacggt
    42721 ttcatgttct ccttcagcag gaatcacaat ggttacctta tcatccttag ctagagaaaa
    42781 caagacattt tctacttgat cattaacttt gatttgaccg ccttgaaatt ttattttcgc
    42841 taacagaccc tttgagatcc ctttttcttt taaaaaatat tttacttgct gagaatgatc
    42901 tttctcataa tcccatgtaa actgcatatc aatcctcact aataaaggca tctttcacac
    42961 gatgccaaaa atgcatatgt cgataagaag caaaatggat ccgttcttct gctattcgat
    43021 aataaattga gcggatattt gcttttgcga cattcaattg atcaaccgtt acaagataat
    43081 cttctgtatt ttccaatttt atttctagcc attcatcatg ggcaatcacg atcggagaac
    43141 ccaaagtacg aaacactcga ttattcagtg aagcaatctc tgccaactga aaggcattga
    43201 tactaggatg gatcacagca ccgccgacac ttttattata tgctgtcgaa ccagtaggcg
    43261 tagaaatcgt caatccatct cctctaaaac tttcaaacag ctcgtttttg atgtatacat
    43321 cggctaccat cgtacgattg gcccgtttaa tcgttgattc attcagtgct aaaaaatgct
    43381 ggtccggtgt ttcatccaaa taactgatcc gaacatccag caagggataa ctaacacttt
    43441 gttcccggtt cgttcgtaag ctgtctacta gttcttccag ctcgtaatcc cgccaatccg
    43501 tgtaaaaccc taaatgacct gtatgcacgc ccaagaaacg cacatcattc agacaatgac
    43561 tgtagtgatg gaacgccgac aataatgtgc cgtctccgcc gactgagatg accaattctg
    43621 gctcatgatc atctcgttga atccctgctt gttctaaaag tgcgttcaaa cgttctgtca
    43681 cttctatagt ctttgcttct ttattatgaa cgatcgctac tttcatcccc tgcctcctct
    43741 ctttcgcttt ctttcttcaa aagcgttcga tagtagacat catctgattt tcctcttcca
    43801 tgggagaata accgctgtgc ttcttggatt tcttcacgga tactggacat ctcttcatcc
    43861 aactgatagg cagcttctgc cgcacgctga agtcgttcac tcatttcttc tggaaaaacg
    43921 ccttgatatt tataattcag cgaatgctca atcgttgccc agaaattcat cgcaagagtc
    43981 cgaatctgga tttccgccaa aattttcttc tcaccgctga tcagctgtac aggatactcg
    44041 atcaccagat gataagaacg gtagccactt gcttttttat ttgtgatgta atctcgttct
    44101 tggagaactt tcatgtcttt tcttttacgg atgatctcaa caacttgatg gatatcttct
    44161 acaaactgac acatgatcct taacccggca atatcagaca tttcttcttc taaacgtccc
    44221 attggaatat gccgtaattg tgattttgtt acaatactat cgactggctt gactctccca
    44281 gtgacaaatt caatcgggac atgtcgattt tgttcacgga actgtttgcg gatcccccgc
    44341 agtttcactt tcaattctga tacagtttgt tcatatggtg ctaaaaatgc ttcccaatct
    44401 cgttccatag ctgatacctc tacttcatta acattcattg tttattctac catatatgca
    44461 aagttttttc gtactcttga tttatgcatt gaccaaaaaa agaaaattag gcaaaataga
    44521 caaaaaggag tcgatcaaat gacacaaatg cttgaaatcg aatataaatc tatgctgaca
    44581 aagcaagagt acgagatatt catcgctcac tatcaattaa cagataaaga tttccgtgta
    44641 cagactaata tttatttcga taccgttgat gaacagctga agaaacaaaa ttgtggccta
    44701 cggatccgtt tcgttggtca tcaagctgaa tatacattaa aaacacctgc tgaaaaaggg
    44761 cgtctcgaaa caacggatac ctttataaca gaagaagcag aagcatttat cttcgaaaaa
    44821 cgtctgcctc gttcaggcgc agtttttcaa aaactttctg atttgaatat cgatcctgct
    44881 tcattaatcc aaaccggaaa gcttacaaca aaacgggctg aattccctat tgaagaagga
    44941 cttttagcta ttgatgaaag ctggggagac aatctacacg attttgaact ggaactagag
    45001 gtaggggatg catctgtggg aaaaattgct tttataaatt ttttaaaacg tttttcttta
    45061 ccttatcgtc ctgctaagaa caagatccaa cgtatgcttg aagctaaaaa ttagaaacct
    45121 ttcattttca caaggcactt gagttcattt ttttactttt ttctgttaag ttataggatg
    45181 tgaaagaatc tagtcactag ttgtatagaa tctattttgg gggagattca tatgatcgaa
    45241 atctatttat ttgttaatcc tttaggggaa tactgtttcg aaatggaaca acagttatta
    45301 caatttatcg aagaagagta cgggacacca tcaaaagaaa agatgcaatt tcgctttctt
    45361 cctttggtca atttgcagac aattggggat gtcatgcaac aaaaaggaat ttctcagaac
    45421 aatcttgagg aacgtaatca cttattctca atgacttatt ctgcagcatt ggactgcaaa
    45481 gcggcgcagt ttcaaggaaa gaaaaaaggc cgccgttttt tgatcaaatt gcaagaagca
    45541 gtcggctgta atgacatacc atattctcaa gaacttgctg aatccatatt tgaagaaatc
    45601 ggcggcgatt tgaatatgtt taaagaagat cgtcagtctg acttcgttaa agaagtattc
    45661 ttttctgatc aaaaaattgc tcgggaaatg ggcatcacaa aacacccttc tgcagtcgtt
    45721 tacaattatg cctgcgaccg tgattttggt gttttagtag aagtaaaagg tacaagtagc
    45781 ctttggagaa tcacagagct gtgtaaaaca acagataact catatcaagt ttttaatggt
    45841 gaacatttac atacaaatga ttctcagttc cattcaagaa ctagccattt acacttgctt
    45901 tctaattaaa aaaatacgtc gactccctta caagagagcc gacgtatttt tttcgtttct
    45961 attcgagaaa atcaaaaata gaaagcctta taaacgatcg atcaattctt ctaattcatt
    46021 tagacgttgt tcaaacatcg acattgcatc ttcaatatat gcagcctgtg tcatatcaac
    46081 tcctgctttt ttcattactt ccacaggata atcgctgtta cctgctttta ggtaagccaa
    46141 gtagttctct agtgcctctg gttcctggtt tagtattttc ttcgccagtg ctgaagcagc
    46201 agaaaagcca gtcgagtatt ggaaaacata gtaattataa taaaaatgcg gtatccgtga
    46261 ccattcgaat ttaatttctg ggtcttcttc gactgctgga ccataatatt ttgcattcaa
    46321 tttaccataa ctatcactta ggtattcact agtcaatggc acaccttttt catcttccgt
    46381 atgcatgaaa tgctcgaatt cagcgaattg tgtctggcgg aaaactgttc ctttaaaccc
    46441 atccaagtaa tggttgagta cataagcccg tacacgaggg tctttttctg tttccaataa
    46501 atactccgtt aggatatttt cattcgttgt cgaagcaatt tctgctaaaa agatggagta
    46561 gtcgccgtac acataaggct ggttcgaacg agtgaaataa ctatgaacac tatgtcccat
    46621 ttcgtggaca agcgtaaata gctgatccag cgtatcatgc caattcaata aaatatatgg
    46681 atttgtgtca tagcttcccg aagaataagc atcgcttcgt ttccctttat tttcgacaac
    46741 atcgatccaa cgttcagaga atgctttttc tacgatggcc atgtattctt cacccattgg
    46801 tttcagtgct tctaaagctt tttcttttgc ttcttcgtac gtaaaggtaa ttggagcttc
    46861 ccctaagacc ggtgtataaa gatcatacat gtgcagtttt tccacttcta ataaacgttt
    46921 ccgtaattcc atgtatcgat gtaacaaagg caaatgcttg tttaccacgt ctaccaaagt
    46981 atcgtataca ctttcaggaa tatgattatt gctcaaagac gcttctctgg cagagctgta
    47041 attacggact ttcgctttaa aattatgtcc ttttatatgt gtgcctaaag tagaagcaaa
    47101 tgtatttcta aattgttcgt aaacactgta caatccctta aatgctgctt cgcgcaccct
    47161 tcgatccgtg ctttctagca actgaccata cacgccatga gataattgga ctatttcacc
    47221 attttctcct tcaatcgttg gaaaaactag atctgcatta ttcaaaacag caaatgtatc
    47281 acttgaagca tcaaagattt cacctgctcc agcaagaaga gattcctgct cagcagataa
    47341 gacatgggct cgattatcta ctatttgctg gatataatgg cgatagactt ccaattttgg
    47401 ttcttctttg aaatattgcc aaatctggtc atctgacaat tgcaatattt ctggttcaaa
    47461 ccaggaaacg gcttcactaa ctttcgaaaa cagactgctt gctcttgcat aaagcgcttg
    47521 gtaatctgta tttccagtgt cttgatcgtt tttaaggtgc gcatatacat aaatgacttc
    47581 agtttggcga taaaccctca atacgaattc aatcgcattt aaaaattgag aagcgccttg
    47641 atcaagtgtt cctttgtgtt tttcagattg ttttaactct tctgataatt ccaaatattt
    47701 ctcatcaaac tcttggtcgc ttgaaaagat cttggtcaag tcccaagtta aattttcagg
    47761 caattcttct cgttttggca actgctttac ttccatgaaa tccactcctt ttcttccctt
    47821 agctctatct atcaaaatag atcatagtct aacatccaca tgtcacagca tctaactttt
    47881 ctactcattc atgtgtctgc ttccatcaat tttagcataa ctaaatcttg ttttacatag
    47941 aaaaccgatt cctagcctat ttttatactt actatttttt caaagaagac aagtgtatgc
    48001 attcgttaaa aaactgctga tagaccatct cttcatcaat cataggaaaa agccattccc
    48061 ttttatgttc ttttatttgg caaagccatg agttgaaatc aggaactttc tggttttcca
    48121 aggcttcttc gtacaacatt cgataaagaa aaacctgttc ttgtaaataa aagaaaaacc
    48181 gacttttttg atagatccac gatgatagat gcaaaagatg tttatgacgc aagtagcatt
    48241 gttcttgtat ggatactgta ttcttttgct tgtgaataag ttggcgtgtc agccatttct
    48301 tcccatcttc actcactttt tctatttttt tcatttggtt cattttaatt tcgttactag
    48361 tgaatatttc tttaaggtcc ctactagaaa aagtccagca gctactgcaa aaggaaatat
    48421 gccctgatac agtctctgta atatgatgat acaaataaag cttttgtttc ttgagatcag
    48481 ctttccagca atgcactcct ctttttctat tatagtagca gcaacttttt tctatcaatg
    48541 agaattgcga ttgtccaaga aaagaattac caagtatcca ccatacttgg taactgttat
    48601 tcaaataatt ttgggttctt tcaataaatc tctggtgaga cagtctagaa cattggattt
    48661 ctattgctag attcgccaac aaaatatccg gcctttgccg caacctcggc aaataggctt
    48721 ccaaaaatac tggttctact gactgtccca gccaatccat gaagcattcc tttaactgta
    48781 agtgctcttt tgattctctt tcactaaaga ccgaacagtt atctgatttt tgatgggcaa
    48841 aatgagcaca ttttttcttt ccctttttca aaatcactct ttttcgacag ccacgacaat
    48901 aatatttctt tcctttttct gcatgtttag caaaacagca cttattatat tcattcattg
    48961 caagcagcat ttttctccct ctgaacttat ttacgtctaa gaatttattt acacgaaaaa
    49021 agagggcgtg aaaaagctat tctgcatcaa gtaataagaa cagctaaaca aaaatagttc
    49081 ccaatatttt tcgtttggtt gggcttgtta ccgcagatgc aagcttttga acacatttat
    49141 acgaaaaaaa gactgcgaca caatttttgt cacagtctct tactataatg ctgatttata
    49201 caaaataaaa tttcgttcgc tcgatagcat tacgcgccat cagacattgt ccatattcat
    49261 tcaatgtttc tggtgtacga tcgctctttt cagcaaactc caaaattcga gcaatctgat
    49321 tctctacatc cgcttggttg agattttcca tccagaagtg aacgactagg taatagcgct
    49381 cttcgaataa atacaaatca gtccaagcag actctagttc gacatctgtt gcaagttgga
    49441 tcacttgttc aaaatcttca aaagcaaaag ttgcttgtct ttcctgttct tctagggcgc
    49501 ttccagataa ttcttcctcc ggatcgctgc caataatctg ctgacgaaga aagtcactca
    49561 catcttctga atcaacagta gaatcttctg attgagaaat ttcttcatcc ggaagatttt
    49621 tactgataaa cagttctaat ccgtctcctt ttggcaaaac ttggaaagtg acagcttcgc
    49681 ttcctcggaa ctcctcttcg atatcaactt cttccaaaat actataaaag aaattttcga
    49741 tttctttgtg attgccaagt aaatccaaaa atgaaacgcc ccgttcctct aaatcttcat
    49801 gaccaattag tacacggatc gtattttcat taatatgttc catttccatt ttgctacacc
    49861 tcactttgcc acaatgttta atatagattc attgtagcga aatcagctta aatgtaaaga
    49921 aaaaaaatct cgctgttaag cgaatttaat aaaaccagcg gatttttcaa cctttcaagc
    49981 tatcttattt aactataaca tttttggcag acgaatacta tatagccgac ttttcagcta
    50041 attttccctc tctatttttc gtgcaatcat catcttctac taccttttta tacatctaat
    50101 caagaatact ttttgtaaaa acaaaaaaac ttggaaaaac tatctttgta atagtcttt
//
LOCUS       DAZKCW010000018        49127 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000018 DAZKCW010000000
VERSION     DAZKCW010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.018"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1279)
                     /locus_tag="ACG84Z_001100"
     CDS             complement(<1..1279)
                     /locus_tag="ACG84Z_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HFP9161954.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQ"
     gene            complement(1865..2395)
                     /locus_tag="ACG84Z_001101"
     CDS             complement(1865..2395)
                     /locus_tag="ACG84Z_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFP9161955.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            2500..3051
                     /locus_tag="ACG84Z_001102"
     CDS             2500..3051
                     /locus_tag="ACG84Z_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFP9161956.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(3204..3677)
                     /locus_tag="ACG84Z_001103"
     CDS             complement(3204..3677)
                     /locus_tag="ACG84Z_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFP9161957.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            3815..5287
                     /locus_tag="ACG84Z_001104"
     CDS             3815..5287
                     /locus_tag="ACG84Z_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFP9161958.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            5284..5994
                     /locus_tag="ACG84Z_001105"
     CDS             5284..5994
                     /locus_tag="ACG84Z_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFP9161959.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            6346..6630
                     /locus_tag="ACG84Z_001106"
     CDS             6346..6630
                     /locus_tag="ACG84Z_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFP9161960.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(6911..7330)
                     /locus_tag="ACG84Z_001107"
     CDS             complement(6911..7330)
                     /locus_tag="ACG84Z_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFP9161961.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(7332..7916)
                     /locus_tag="ACG84Z_001108"
     CDS             complement(7332..7916)
                     /locus_tag="ACG84Z_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFP9161962.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(7963..9438)
                     /locus_tag="ACG84Z_001109"
     CDS             complement(7963..9438)
                     /locus_tag="ACG84Z_001109"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFP9161963.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            9619..9930
                     /locus_tag="ACG84Z_001110"
     CDS             9619..9930
                     /locus_tag="ACG84Z_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161964.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(10045..12381)
                     /locus_tag="ACG84Z_001111"
     CDS             complement(10045..12381)
                     /locus_tag="ACG84Z_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFP9161965.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            12523..13191
                     /locus_tag="ACG84Z_001112"
     CDS             12523..13191
                     /locus_tag="ACG84Z_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9161966.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            13194..14237
                     /locus_tag="ACG84Z_001113"
     CDS             13194..14237
                     /locus_tag="ACG84Z_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9161967.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(14474..15355)
                     /locus_tag="ACG84Z_001114"
     CDS             complement(14474..15355)
                     /locus_tag="ACG84Z_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9161968.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            15514..16242
                     /locus_tag="ACG84Z_001115"
     CDS             15514..16242
                     /locus_tag="ACG84Z_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFP9161969.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            16398..16715
                     /locus_tag="ACG84Z_001116"
     CDS             16398..16715
                     /locus_tag="ACG84Z_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFP9161970.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            16708..17316
                     /locus_tag="ACG84Z_001117"
     CDS             16708..17316
                     /locus_tag="ACG84Z_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFP9161971.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            17371..18162
                     /locus_tag="ACG84Z_001118"
     CDS             17371..18162
                     /locus_tag="ACG84Z_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFP9161972.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            18300..18788
                     /locus_tag="ACG84Z_001119"
     CDS             18300..18788
                     /locus_tag="ACG84Z_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFP9161973.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            18839..19711
                     /locus_tag="ACG84Z_001120"
     CDS             18839..19711
                     /locus_tag="ACG84Z_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFP9161974.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            19887..20249
                     /locus_tag="ACG84Z_001121"
     CDS             19887..20249
                     /locus_tag="ACG84Z_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFP9161975.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            20258..21010
                     /locus_tag="ACG84Z_001122"
     CDS             20258..21010
                     /locus_tag="ACG84Z_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161976.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILIVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            21024..22826
                     /locus_tag="ACG84Z_001123"
     CDS             21024..22826
                     /locus_tag="ACG84Z_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9161977.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            23103..24143
                     /locus_tag="ACG84Z_001124"
     CDS             23103..24143
                     /locus_tag="ACG84Z_001124"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFP9161978.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(24195..26339)
                     /locus_tag="ACG84Z_001125"
     CDS             complement(24195..26339)
                     /locus_tag="ACG84Z_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFP9161979.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(26696..28069)
                     /locus_tag="ACG84Z_001126"
     CDS             complement(26696..28069)
                     /locus_tag="ACG84Z_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9161980.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSSKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(28069..28464)
                     /gene="rbsD"
                     /locus_tag="ACG84Z_001127"
     CDS             complement(28069..28464)
                     /gene="rbsD"
                     /locus_tag="ACG84Z_001127"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFP9161981.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(28492..29409)
                     /gene="rbsK"
                     /locus_tag="ACG84Z_001128"
     CDS             complement(28492..29409)
                     /gene="rbsK"
                     /locus_tag="ACG84Z_001128"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFP9161982.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(29517..30530)
                     /locus_tag="ACG84Z_001129"
     CDS             complement(29517..30530)
                     /locus_tag="ACG84Z_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFP9161983.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(30611..31210)
                     /locus_tag="ACG84Z_001130"
     CDS             complement(30611..31210)
                     /locus_tag="ACG84Z_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFP9161984.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            31396..32097
                     /locus_tag="ACG84Z_001131"
     CDS             31396..32097
                     /locus_tag="ACG84Z_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9161985.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            32107..34818
                     /locus_tag="ACG84Z_001132"
     CDS             32107..34818
                     /locus_tag="ACG84Z_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFP9161986.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            35269..36897
                     /gene="treC"
                     /locus_tag="ACG84Z_001133"
     CDS             35269..36897
                     /gene="treC"
                     /locus_tag="ACG84Z_001133"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFP9161987.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(36957..38138)
                     /locus_tag="ACG84Z_001134"
     CDS             complement(36957..38138)
                     /locus_tag="ACG84Z_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFP9161988.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            38390..39913
                     /locus_tag="ACG84Z_001135"
     CDS             38390..39913
                     /locus_tag="ACG84Z_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFP9161989.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(39982..40710)
                     /locus_tag="ACG84Z_001136"
     CDS             complement(39982..40710)
                     /locus_tag="ACG84Z_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFP9161990.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(40723..42003)
                     /locus_tag="ACG84Z_001137"
     CDS             complement(40723..42003)
                     /locus_tag="ACG84Z_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFP9161991.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVALIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(42144..42746)
                     /locus_tag="ACG84Z_001138"
     CDS             complement(42144..42746)
                     /locus_tag="ACG84Z_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFP9161992.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            42991..43197
                     /locus_tag="ACG84Z_001139"
     CDS             42991..43197
                     /locus_tag="ACG84Z_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9161993.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            43509..44228
                     /locus_tag="ACG84Z_001140"
     CDS             43509..44228
                     /locus_tag="ACG84Z_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFP9161994.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(44309..44992)
                     /locus_tag="ACG84Z_001141"
     CDS             complement(44309..44992)
                     /locus_tag="ACG84Z_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFP9161995.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            45210..47396
                     /locus_tag="ACG84Z_001142"
     CDS             45210..47396
                     /locus_tag="ACG84Z_001142"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFP9161996.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            47742..48152
                     /locus_tag="ACG84Z_001143"
     CDS             47742..48152
                     /locus_tag="ACG84Z_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFP9161997.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            48166..48522
                     /locus_tag="ACG84Z_001144"
     CDS             48166..48522
                     /locus_tag="ACG84Z_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFP9161998.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        15906 a         8687 c         9768 g        14766 t
ORIGIN      
        1 attgattgat caaaaagatt ctaattctca tgttctcaaa tgatttaaat ccgtaggata
       61 ctcgtttcat tgtctttata tgggtattct tcgcttctat ttttccattg gtgtaaggat
      121 agatcatcgc gttggtgatg ccttcttcat aggtcagaag gttttggagc ttttcccgaa
      181 agccgtcatc taacgtttcg ggaagttctg ccaataagga gaaaaataag tcagggtctt
      241 tgtctcgaaa ggcttcaact aattcatgaa aatagggata cgcctccttc agggacgtag
      301 aaaagccaag caatcgatca atcatcatcg cttccgtaag aaatgggtat tttggtgctc
      361 gaaaactttt ccatgttttg tattcataat ggttgatgtt tgcacgattt tttagcaaaa
      421 agcgccagtt ctttttcagt ttttctgcct gacttttctg tcctacttta cgaagttcat
      481 tcatttcacg gatacgcaac tcattaaagg cttgattcat gtgtttgata atatgaaacc
      541 gatcaatcac tactttcgca tttggcagaa tacgtttggt aagctggaag taggcggcgt
      601 tcatgtctgt gactaaaaat tttacttctt caggattagc gcagcctaag aaatagcttg
      661 ttaatcgagg caatttacgc gtaggcaaga catcaattaa ttgtcctgtt tcgccatctg
      721 cgcaaataaa gctcatttta tcttctatgg aagcgtgcga acgaaattca tcaaccatca
      781 atactctggg gagaatcctc ttagattgct ttggtaagta gcttttaaac tctttcaacg
      841 tacgaataac ggtggtcaaa gatacctgac aatttttcgc aataaaagat aaagatactt
      901 tttcagtcag taaagaagca attttatatc tgacatgatt cgcgattgaa tgtctgggtt
      961 gaacaaaata actttgagcc gtccaatggg ttcgacagtt tttacaggta tagcgctgct
     1021 tttttaagcg cataaccaaa ggcatgtgat tgtattgttc aaagcggaca atcgtttcct
     1081 tcttcccatt tttcactaca attactttcc cgtttccatc taccacagta gaaccacaat
     1141 ttctacaggt atggggagca ggtgagaaaa cagcatcgac gatcaacgtc tttttcttct
     1201 gaaaggtctc gtaagagacc tctgtaatca tcaaatcttt ctctattaat cgcagcattt
     1261 ttttgataga atcattcata tagcatatcg tcctctcagt tgtttatttt gtcgtgattt
     1321 aatcatacta gagaacgata tgttttttaa tacctaaaat aaaaatgggg ctgaagaatc
     1381 aattctgatt catcagtccc ataaattata gagccatttt ttgctgggag cattatttca
     1441 ttttgaagtc actaatttaa ctgtgtgaat atgcagttgt tacaatcttt gataaacggt
     1501 gttcaatcag ctgaccctcg gtattagctc aaaaaacggc aaaatatgag gaactatttt
     1561 tccatttgtt tctctaatac tcaggtcaaa acgctgattt cacaacctct tgataaacgg
     1621 tgttcaaacg gctgcttctc ggtaataagc ccactagcct agaaaatatg aaaagctatt
     1681 ttctaactag cgttcttatt actcaaagca taacgctgat ttcacaacct cttgataaac
     1741 ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac ggcaaaacat gaggaactat
     1801 ttttccgttt ctttctctaa tactcaggtc agaacgctga tttcacaacc tctctttcac
     1861 aaccttattt tactcgttta taattttcat cgaagtattt tccgctacgg atatcatctg
     1921 gcattccatc gtatggttct tcgctaataa catcttcatt gtctatacct gcatcaccca
     1981 tataagtgat cgtagcaaat tcaggaacaa gtaattttgg ataagtttca tatttttcac
     2041 gagctgcttc catttctgcg atatgttcgt tttggaaagt aacagtgatt tctggatgtt
     2101 cttcaaccca tttagggaaa aagatcattc cgtgaagttt cttttcattt ggcataaagt
     2161 ccaatgccac gtctgtccct gttggctctg tccaagtgat tttgaatacg ccgtccgtca
     2221 atttaacgat atcagcttct tggtctttta cccaacggcc tttgaccatt ccgccatgga
     2281 tacggtaatc aacagtatgg tcatttttgg cataccattc atattcccaa ccattgtcat
     2341 acgtatagat aaagtgagtt ccaataaaat cttccaattc tttaaattct ttcatgttta
     2401 agcatctcct tataaattaa aacatgtaat aaactacatg ttttcgatta ctcatttatg
     2461 atagaatgga tttaaagatt tgtcaaggag ggaaaactga tggcaagaaa aaatacactt
     2521 cgatatattt tgttagggtt attaagtaag aagaagatga caggatatga attgaatcaa
     2581 tcgttcaaaa atgaaatagg agaattttgg caagcaaaac atagtcagat ttatcctgaa
     2641 cttgcaaaaa tggaagagca aggaatcatt cagcatcaag tagagatcac aggtgaaaaa
     2701 ttggaaaaga aagtttatga attaacagaa gaagggaagg aacaattggc agagtggatt
     2761 catacaccca ccaatgaact accggttaat cgagacgaat ttgttctgaa attgtatttc
     2821 gtcaaagacg tgaatgatcc ggcattagta gaaattattc agcagcagcg tgaccttcat
     2881 gaagaaaaac gacttcatct attagagcga aaaaaaacga tctttcctac tgaaaaagaa
     2941 aaacatgaaa attacggaca ctacctgatt ttagcgcatg cgatcaatcg ggaaacagaa
     3001 tatgcaaatt ggctaacaga tgtattagaa gaaagtaacc gaaaaaaata aaaaaatatc
     3061 cgaacagtga tggagaattc ctttctatat gaaagaaacg cagatcaccg ttcggatatt
     3121 cttatgttca aacaggcctt ttttcaagta tttatgtagc atctacttat taaaaagctt
     3181 ggtacttagg agattagtgg cgtttagagt tcttttaaca actgttcgta gtcagctttt
     3241 tcatcgacag gaaggagctt gtaagttaat tcgtctgtct cgttgtcatg aatgatgtac
     3301 atcttagcat tctcttcttt gaagttaccg atttgtaaaa tcgtatagcg ttcgtcgatc
     3361 aattcgatat ctttgattgc ttttgaaaaa actttacgga catggtgcat tttcttttgg
     3421 cggatttctg ccttttctgc agcttttgac aaagtaaatc cgtcatctaa atattttttg
     3481 atcagttcta cttttatgac tgtaggtaaa cgatattttc taggacaatt cgcatcagct
     3541 tcgatcgaac gaatgaatcc cttttgttcc caatacctta attgacgtgg agacacacct
     3601 acgatatcac ttaattcact gatgccaaca accaattgat cattttccaa caaacgttta
     3661 agggaagccc caaccatttt tgtcactcct tttgtcctct tgcttccctt aattatatcc
     3721 gtattaactt atgtgtcaag taggttgaca aatagcgaat ttaggactaa agtattctag
     3781 tagtttcaga aaaaattcag aaagaaggag aaatatgagt aacaaccaac ccgtagatat
     3841 ttacggaaaa ccatataatc ggacactttt agttgttgtc ttattaattg gtacattttg
     3901 taccgttttg aatcagacct tattgacgac agcttttcct acattgatga aagctttcga
     3961 tatttcagcg tctgatgtgc aatggttaac gactggtttc ttgctagtca acgggatcat
     4021 gatcccaata acagcatggc tgatcaataa attcagttca agaaatttat atctttctgc
     4081 catgacgatc tttttgatcg gaacgattac ttgctttaca gcacctaatt ttagtacatt
     4141 actaatcggt cgtttgatcc aagcttgcgg tgtgggagta tcgatgccat tattgcaaaa
     4201 tatcatgcta tctattttcc cgccagaaaa aagaggatca gcaatgggga tgtcagggat
     4261 cgttattgga cttgctcctg ctttaggccc tacattatct ggttatatca ttgataacta
     4321 ccattggcgt gacttgtttg gtatggtact gccaatcgtt gttcttgtct tggttttagc
     4381 attcttccta atgaaaagtg ttattccatt gtcaaatcct agcattgata ttttatccgc
     4441 tattttatca acgattggat tcggtagttt actttacgga ttttctagtg taggagatga
     4501 cggctgggga agcttgaaag taattggttt cttagttgtt ggtgtgattt tcatcgcctt
     4561 gttctcatgg cgtcaattac atttggaaca tccattcttg gaacttcgtg tattcaaatc
     4621 atctacattc acgattgcag ctgttttagc tggtgtaaca aatatggcga tggtaggggc
     4681 agaaatggtc gtaccattgt atattcaaaa tattcgtgga gaatcagcat tccattctgg
     4741 cttgatgttg ttgccgggtg cattgatcat gggggctatg atgcctgtga cgggtgcgat
     4801 tttcgataaa tacggcgcga aacgtttagc catcacaggg atgttcattt tgacagcggc
     4861 aactgcacca tttgctttct tgacaaaaac gactccagtt ttatatatcg tgatccttta
     4921 tgcgatccgt atgtttggga tctccatggt catgatgccg gtaacgactt ctggtatgaa
     4981 tgcattgcca aataacttga tcagtcatgg gacagcggta aataatacat tccgtcaaat
     5041 cgcaagctcg attggtacag ctattttgat cagtgtgttg acgaatgtga caaaagcaaa
     5101 tatcccaagc aaatctgtat tggataatac gccattagct tataaagatc aggcaatcaa
     5161 tgccacactg tcaggttacc atgccgcgtt tatcgtagcg atcatctttg ggattcttgg
     5221 ctttattatt gcctttttat tgaagaaaaa agaacctgtt ctaatgaaag cgggggataa
     5281 tgcatgatta ttggagtttt gattgtcagc ttgcttgctt ttgctttaac gaacgtgttc
     5341 gctaaaaaaa catggcaaac ctttttatct ttgattttcg gactaatctt cgtcgcttca
     5401 ctaagtttga tcgtcgctaa tttgtccaat cactttggaa tggaaaaagt aacggaaaca
     5461 aaaacagaaa aaattgtttc cagtgctgat tcccaaggag cagatatgct tttgtataaa
     5521 gctttaggga atggaaaaga aaaagtgtat ctttaccgaa caaatgaaaa acaagaaaaa
     5581 ccaaaagcaa ctggtacgga taacgaaaca aataaagtag aaaagacaga cggcgatgct
     5641 gaaaaagtga cgaaaactac ttattgggaa tacaaaaacg acatgtataa attctggttc
     5701 aatattgctg ataacaatca cgaatatgac agccgagtga atacattcaa aatcccagag
     5761 acatgggtag aattaagtac ggaccaagca gccaagttag ctgaattagt gaagaaacag
     5821 caaagtacga tggaaagtga agcaaaagct tatgttcaag acggtatggt aaaagcaatg
     5881 actgaaaatc caaaaatgag caaagcagag caagaacaac gtacgaaagc cttagctgct
     5941 gaattccaac aacaagcatt cgcaaaatta gtgaaagaag caaaaggcga ataatatttt
     6001 gaacaccatg taggaggttg tgaaaaagct gctctgcatc aagcagtaag aacaatcaga
     6061 taaaaatagc actccatatt tttcatctga ttgggcttag tgccgtagat gcaagctttt
     6121 gaacaccgtt taaggaagag gttgtgagcc tgccgtttaa ctctgagtca caaggagcaa
     6181 tttcaaaaaa cagcttctca tgtttgttga ctattgtgac ttgtgaccga ggagttggca
     6241 ggagaacacc gtttattcga aaaaaggaac tgcgacaaga cttttgtcac agttccttct
     6301 tttttttgct atgctatact agatgtaaaa aataggagaa ataaaatgag ggaaatttat
     6361 tcttttgaat caaaaatcta tgcttccgaa gtcggcaagg gcggggcata tattattttt
     6421 ccgtatgata taagaaaaga attcggtgct ggaagagtta aagtccaagc aacttttgac
     6481 aatgtgccgt atgaaggcag tatcgtgaat atgggcgtga aaaatccaga tggttcagtc
     6541 tgctacatcc ttggactacg aaaagatatt cgtaaaaaca tcggaaaaga aatcggtgat
     6601 attgtagcag ttacagtgaa gcaaaaataa aagaggttgt gacaaaagac gtgtcacaac
     6661 ctcttgataa acggtgttca aaagccagtt tctcggtagt aagtcaaatt tatgcaaaaa
     6721 tgtggaaacc catgtttaca aaatttttct tactactcga aacgaagcgg ctttatcaca
     6781 acctcttgat aaacggcgtt caatcagctg tccctcggta ttagctcaaa aacggcaaaa
     6841 tatgagaagc tatttttcca tttttttctc tcatactcag gtcataacgc tgatttcaca
     6901 acctcttctt tcataatggt ttttcaccat ctttataata aactggttct ttgatatgga
     6961 aatctatttt ttccaaccaa tctaaaatct tgtaacctaa ctcttctgac atcggaaaag
     7021 aggcgttgat ttgtgcattg gagatatggt caacatggat accggaagtg atcgtacaac
     7081 ttcccggaac ggcagttttg atgatcacag ctattttttc ggctaagaca tcgtctttat
     7141 ggaaccgacc atcgtggcta gggaaacgta cagtttgcat ctctgtatca cgagaaaatg
     7201 tagtgactgt tccgatatgt ggtgtatctc cgcctgttaa agtgatcaat aagtctttac
     7261 cgattacttt aacagcagct tggatcgtga aacctagttt ggttacttca actatcgttt
     7321 ctttttccat attaatcacc ctgccaacgt tttgaatgct catttacaat ttcaaattga
     7381 tccaaaagtt tcattgtatg gtgattaaca agatcttgga tcgtttgagg ctgattataa
     7441 aaagcaggaa ttggtggtat gatttgcaca cctagtcgtg ctaatttagt caagttttcc
     7501 aagtgaatgg catttaatgg cgtttcacga ggaacaatga ctaactttcg ttgctccttc
     7561 attgttacat cagcagcacg tgcaatcagg ttgtcgccta aaccaacaga gatacctgcg
     7621 actgttttca tacttgccgg tacgatgatc attccatcgg tcaaaaatga tccgctggcg
     7681 acagcagcac ctaaatcttt gtttgaataa tggtaatcaa acaggctttc gaattcagtt
     7741 agtgataagt cggattccag ctttaagttc tgttttgccc atggactgat gattccgtgt
     7801 gtttctatca tcggatattc ttttagtttc ttcactaggt tgatggcata aatggtgcct
     7861 gaagcgccac ttacaccaat cacgattttt ttcttccgtt gtgccaattg ttccattttc
     7921 cgcactcctt tttatgatgt caaaacagtt gcagatcatt cattatttca aatatttttc
     7981 ccaatcttct acttcttgga attttgcacg tacaaaatgt tctttcatat cgaaaggaac
     8041 tgtaccgtca aagatagttt ttgcacttat cccacggaaa cgaatagagc caggattata
     8101 ttctggtaat tctgatgggt ccaatggatg gttcctcatt cctgggatca cgatgatatc
     8161 tttatctcct tggaaacgag tgttgaaagt ccaaactaca tcgttcatgt cgaaaatatc
     8221 aacatcttca tcgactaaaa tgactgtctt caattctttg aaggctgata aagcaagaat
     8281 agctgcttga cgctgaatac cttcatccgc ttcgttttct ttacggattt gcatgatggt
     8341 catcaattta ccaccacctg caggaggatt gtagacattt actacttttc ctggaatagc
     8401 tttatcgacc aaggcaagaa tacttgcttc tgtaggaata ccggccatag atacgtgttc
     8461 ttcactggga ccaatcgttg tttgcatgat tggattgtct tttcggtgag taactgcttt
     8521 gactttcact acttgtacag ctggattagc atccccagta tagccaggaa attctggcat
     8581 tgcttttcct gagttcgtgt tgatatcttc ttgcattgtt tcatttggca tgatttctgc
     8641 ttcaatgatg aattcagcac gagcaatacc cacttcatcg actgctatac catcaacgat
     8701 ttgaataggt tcgttacgca aagctcctgc acaccatagt tcattgtagc caagtggagt
     8761 ggtaggtggt tcgaaagtcg tgccaatggc aattgctgga tctaaaccaa tattgatagt
     8821 gataggcatt ggtttattca aggcttcgaa ttgtttttgg aagtgaccaa tgtggcgtcc
     8881 gccaggcatg atgtacatac cgatcgtatc tttatcttct agaaccatac gatggatcgt
     8941 tacatcgctc attgtttttt ctggatctga tcctaagact acacccattg tgatgtatgg
     9001 accagcatct tcaggagtat ttgtaggtgc aggcaaaatg ttgcgaatat cgaagtctgc
     9061 atcggtagct agatgaacga cttcttgtgc tggagcgtct gctttgtcta ctttcacagg
     9121 tttgattgga ttttctacag cgtctttcaa gaaacgacca agtgttcgat aatcatggtg
     9181 caaaatttca cctacacgtt tacgactagc cattgttccg atgttcacac gtgtgccggg
     9241 gaaacctttg atattgttga aagtcatagc tggtccttct tgagtcggac gttttactgt
     9301 accgccagca ccgatataac ggtaaacacc agataattct gcttcaggat cgatttcaat
     9361 atctgtttcg tgatattgac ctggaagtgt ttttagttct tcgatgactt ttcttaaatc
     9421 atacggttga tctgtcatga gagattcctc cttagttgtc tttacctatc tatagtaaaa
     9481 ggtgaaaaag aggaaaacaa ttcaacttgt tcggtaaagt attctacaat ggaatggatg
     9541 cgtttttttg ataatagaat aaactatgat atacttatca ctaaaagaaa gcgcatactt
     9601 agtgttggag gaaggaaagt gaaaaaaatg gaggagtcat ttcctaaagc agtaaaagtg
     9661 gaaaatatag cgaatatttt gaaagttaca tttgaaaacg gagaagtaaa atacgtgaaa
     9721 tctcattgga cagaagagat aaccgatgcc ttgcaatttg gaaaaaaagg aagaggaaaa
     9781 agaaaaaatc ttctcgcact ttctcgtaat atgtggattg ggactgaagt aacgattgaa
     9841 gcagatggaa cagtattcat aaatggaaaa gacaggtata cgccagaaga gttgtggtac
     9901 aaaggaaaga aaagtatacc agaattataa aaaataatta aaaaaaacag cgcgaaacaa
     9961 ggaacatatt acttcctcgt ttcttgctgt tttctactat ttcagcgctc ttatgactca
    10021 aatctaaatg tggttgtcac aaccttattc tgcacgcaaa gcgatagcgg cgtctttttt
    10081 cgctgccatt cgtgcaggaa gatgaccgcc aagcatcgtc aatatagtag agacgatcac
    10141 tagaataatc gcatggacag gatttagttg agcaacattt tttagatccg tcatgttgta
    10201 taagatgcta ttgataggga acgtagctag ccatgcaata aacacaccta atatcccaga
    10261 agaaatacct aaaatacacg tttctgcgtc aaatacgcga gtgatgtctt ttttacgtgc
    10321 acctaaagct tttagtacac cgatttcttt tgtccgttca atcacagatg tataagtaat
    10381 gatactgatc atgatcatac ttgttactaa agagatccct gcaaaagcaa taaggacata
    10441 agtgatagca tccatcaatc cgccagtcag ttcagtcatc gttccagcta aatcagtata
    10501 aatgatttta tcttcatctg atttgccttt attgtaatca tctagataat ccaagatctt
    10561 ttctttgtct tcaaaattgt tcggataaat catgatactt gaaggcaagc tgtctccacc
    10621 taaataacta agcaatgttt gtttggcatt ttcgtcaact ttttcagtag ttaagacatt
    10681 tacaccactg tctctttgag ctttgacgat ttctgattct ttgttttcgt tgacgatttg
    10741 agtcgttaat tgatcgctat aagcgattcc tggagataag agattcattg tagaagaaga
    10801 tttcacgcgt aggatccccg agatcttcaa ttcatcagaa gcattctgat acatcgcatc
    10861 ataatctgta ttagggataa aattcccagt tggaagtttt gtatagtaag tattgttgtt
    10921 tactaatttg aatgttgtac caacgatatc atcaaaatca agtttttcgt cttctttcac
    10981 atcaaatcca agattcttca atgcgttgat attagtatta ttattgccgt ctacgatcag
    11041 cacgacatct gttgctgagg ctggataact tccggcaagt aaagaataat tgtcttttaa
    11101 aaagttttct ttgctagtgt caagctgtgt agggaaactt gacactccca cacctgtcat
    11161 tgctgacatc gtactagata aagaaagaga ttccgtatca ggattttgat tcgagaagct
    11221 gacaggctgt actttgccat ttacatcacg taaaagattg attcctgtag tacgggtaaa
    11281 tccgatatta ttacttaagt taggatcgat gtctgttacg taatcgacgt atgtttgatc
    11341 aatcttattc gtgtgctgtg ctttatcttc ttcgctgact tttgcagtaa tcgttttgct
    11401 gtctggataa tccgctttgc ttgcacccaa tccggcatcg tcacgagtct ggttagtcgt
    11461 taccttagaa atagtaatcg gaaatttcgc catcgtttca gcttgcgtgt tatcgatttg
    11521 tttttggaat ccagaagaaa gggacagaac gatcgcgatt ccgatgatcc caatactgga
    11581 agcaaaggag gtcaagaaag tacgtccttt ttttgttcgg atattgttga aggaaagctt
    11641 taacgctgtc caaaaactca tctttgttct gcgtaagtta aattgatcat cttttggtcg
    11701 ttcgatgtga ggatgggaat ctgttaagat cttaccatca gaaaattcaa tgattcgatc
    11761 tgcgtattga tgggccagtt caggattatg tgtgaccatg atcactaatt tttctttcga
    11821 taactcttgg atcaattcca tgatctggat acttgtttct gtatctaacg ctccggttgg
    11881 ttcatcgcac aaaaggatat ctgggtcatt ggctagtgct cgagcgatgg ccactcgctg
    11941 catttgtcca ccagataact gatttggctt tttatgcata tgatttgtca agccgactcg
    12001 gtgcaatgca tcttctgccc gttttcgttt ttcgtcttta gaaacaccac ttaatgtcat
    12061 cccaagttca acgttttcaa taatgcctag atgaccaatc aagttgtaac tttgaaaaat
    12121 gaaaccgata gagttgtttc ggtaggcatc ccagtcactg tccttaaagt ctttagtaga
    12181 ctttccgttg attaccatat caccggaatc ataattatct agtccaccaa tcacattcag
    12241 catagtcgtt ttaccagaac cactaggacc taaaatcgct acgaattctt tttgtctgaa
    12301 agcgacagac acaccatcca atgctttggt ggtggtttcg ccgactttat aatatttttt
    12361 tatatctttt aattgaagca taatcaccct tctcccgtat tgaaatattc ggtatactaa
    12421 taagtatatc agaacaatga tcgtagtata cgaaataaat gttaactgaa gatgaactac
    12481 aagaaaaaat ctagaaattt ttcaaaaaac agagggagat caatgaatcg tattttagta
    12541 gtagaagatg atccgcaatt acagttgctt taccgttctg tgttggaacg agcgggcttt
    12601 tcagtcatca ccgcattgaa tggagaggat gcgctgaaaa aactagaagc gacacgtata
    12661 gaattaatca ttacagatat catgatgccg aaaatggatg gctatgactt gctagactca
    12721 ttacgtagca ccagatttga cacacctgtt ctaatgatta cggcaaaggc cgattttgag
    12781 gataagaaac gcgggttcaa attaggagca gatgattata tgacaaaacc catcgatgtc
    12841 aatgagatga tcctacgtgt ggaagcattg cttcgacgtt caaagatcaa ttacagcagt
    12901 agcttgataa tcggacaaac aaaattagag ctagatgctt atacagtgtt acaagatcag
    12961 cattcgttga ttctgcctca aaaagaattt ctgcttctgt ataaattact gtcttatccc
    13021 aacaagatct tcactcgcca acagttgatg gatgatattt ggggattaga tacgaataca
    13081 gaagaacgaa cgatcgatgt acatatcaaa cgtttaagga cccgttttga aaagacggaa
    13141 gattttcaaa tcatcacagt acggggacta ggctataagg cggttattta aagatgaaaa
    13201 aaaagctatt ttcacaatta tggatctatt ttgctagtat tgtcttcatt tcgatcttag
    13261 tgacactgct gtgttttctc ggttttattt tcttattgtc tcgacattct atctcgcctg
    13321 ctgaatcggc tggaaaacca acgttatacc cgttattcgt ctttgcgggg ttcagtatgg
    13381 tcgtgggtac aggaatatcg atttttgttg ggcggcgtat cctgcatcca atcagtgcgc
    13441 tagggacaaa tatgagtctg gtagcaacgg gagatttttc gattcgaatg gatgaacagc
    13501 agaaagtagc agaagtacag caactgtata aagatttcaa cgttatggtc caagaactca
    13561 atagtatcga gacactgagg aatgactttg tgtccagtgt atcccatgaa ttcaaaacac
    13621 cactagcaac aatccaagga tatgttcaat tgttacaagc cccaaatctc tctgacgaag
    13681 aacgccaaat atttttatat cggattatcg aaagtatcac gcagctttca caattaacag
    13741 agaacatctt aaaattgaac aaactggaaa accagcgtat ccaactggaa aagaaagagt
    13801 atcgattaga tgaacaaatc agagaagtaa tcgttttttt tcagcctaaa tgggagaaag
    13861 aacagctaga attggatatc gaacttgctg cagtaaatta cacaggcaat gaagagtttt
    13921 tgtaccaagt gtggctgaat atcatggata acgccataaa gtacaatcaa atcaatggac
    13981 agattcatat caaactattt gagacagcca cagagattgt actggaagtg accgattcag
    14041 gtgtaggaat gaatgaagag accagagatc gaatgtttga aaaattttat caaggagata
    14101 caagtcgtca aatttctggg aatgggctag gactttcact ggttaaaaaa attctagaac
    14161 tgcatgatgg acgtattgat tatagcagta tcgaaggagt aggaacgaca gcaatgatac
    14221 ggttaagtaa acaataggaa aaagaataaa acccctaaaa attctattga aggtttttag
    14281 gggtttttag tcgttttttt gtgattaggg aaatgttctt acggttcttt tggcataaaa
    14341 atcgctgctt tcttattgaa ctacgagaaa tgttagaggt gtcattgaaa caaggacatg
    14401 atgcaagaaa gagagcgaaa gtcatgcgtc gctctctttt tttgggtgga tagatggaca
    14461 gaaaatgtag ggcttagttt tcttcttgat ttaaatactc ccaaaatgta tctgaagcca
    14521 aagaatgctc accgacttta cgagtaaatg caagataact ctctgttgtt ggagaaatag
    14581 ggagaatcac agtattttct tttaatagat tcttgactgt tttttccata acaatagcaa
    14641 tccccatgtc atttgcaatc atattgatga tcaagtcgat tcttgctcct ttataagaga
    14701 tttttggttc aaatccagct tcgcgacaca gatctagtac aggttgatac aagttcgtag
    14761 tggggccaag gagcaaaaag ttctcctttt tcagttcgct tagatccaat ttctttttac
    14821 tagctaaagg atgattttta ggtagaactg ctacaaaatc gtctgtttca gtaggcaacc
    14881 actcaatcga acttggtggg gcctggaaac ttctagcaaa gtggatcgtg tcactatgtt
    14941 cattggcgtc attgtaagtt aattcgacac tttccacttc tttcaactgg actgtaaatt
    15001 caggatggcg tttcaaaaac tcggtgattt tggaaaaacc tttataattg atcattgtcg
    15061 gtatcgttaa gatatttaat gaaagattgt tgtctttcgt ataggtttca agcacttctt
    15121 gcatagcatg gtattgttct acgacatttt ttacatatgg gagcaataag cttccagctt
    15181 cggtcaattc gatttttcta tgggcgcgtt cgaataattt gacgtctaat tctgtttcta
    15241 acgaaagaat ctgtttagaa atatttcctt gggtggtgaa ttgtcgatca gcagttttgg
    15301 tgaaattcat tgtttcggct aaatcaagaa aaacttcgaa tttatggata tccatcatat
    15361 tcctcctact tattccaata aagaatactt taacacaaaa aatgaattgg tgtaatcttc
    15421 tctgtctgtt acaatctttc ttgcagcgaa agcaataatt acagaaattt ttctgatttt
    15481 tttcgcttcg tagaaaaaga gaggagtttt ttgatgccaa ctggagtttt gatcaatgta
    15541 ggttccgttt tgtttggcgg actaattggc ggattagtag gaaataaatt aagtgaacat
    15601 tttaaagcac agctgacgat ggtttttggt gtgtgttcga tggggatggg aatctattcc
    15661 attgcgccga tgaaaaatat gccggctgtt atttttgctt tagtgatagg aacagcgatt
    15721 ggtttgattg ttcatttagg taatgggata aataaggggg ctgcgctgat gcaagtacct
    15781 atttctaaaa tcttccctag tgaaaagctt ggtatgaccc acgatgaatt tatcagcaca
    15841 ttagtgacgg tcattgttct attttgtgca agtggtacgg ggatctatgg aagtttagat
    15901 tctgggatga caggagacag tacgattttg atttctaaat ctgtccttga ttttttcaca
    15961 gcagctattt ttgcgtgtaa tttagggtat gtcgtttctg tgatagcaat tccccaattc
    16021 attatttttt atattttgtt cttattggca aaatttattt atccattgac tacaccagac
    16081 atgatcttag attttaaagc ttgcggcgga ttcttgatgg tcgctaccgg ttttagaatg
    16141 atcaacgtga aaatgttccc agtagctgac atgatacctg caatgatcgt tatcatgcca
    16201 ctgagctgga tgtggacaaa ttggattatg ccactgttat aataaaaatc aaagagaagc
    16261 cattttttgc tgactaaaaa ggatcaaatc ttttagtcag tttttttgta tttgacaaac
    16321 tgattttgaa actatattat atgttgtata atatagattg aaataaaata ttacacttga
    16381 gaatagaagg tgacgtaatg cacatccaga ttccaactgt tcttcttgat ggtactgtgc
    16441 tagcagcatt aagcaaggaa gatatgtatg ggtatgcctt aacaaaaatc gtacaagaaa
    16501 gtctctctgt cagtgaatct acactatatc cggttttgag aagattgaaa aaagaaggat
    16561 atcttgagac ctatgatgaa ccttttgaag gcagaaaccg tcgatattac tcgttgacac
    16621 caatgggaag tcgtcattta gaagaaatta ttgatgaatg gattgttttt cgagattctt
    16681 tagaccggtt attggaggag agcacaaatg aatgaatatt tgaatgaagt tgtggatcat
    16741 cttcaagaaa ttcctgaaga cgatcgtttt gatttgatcc agtattatga ggaatatttt
    16801 ttagattctg gaaaaacatt agatcagatc attgatgaat atggtacacc aaagcagttt
    16861 gccttaaaat taaaaatcag ttacttttca gaagaagaac aagcagaaaa cgagttagtg
    16921 aaaaatccaa aaagacaaat tcgcctgatt tggttaatca ttatcggttt atttgcttct
    16981 cctgtcctca ttccactagc actggggttt atattggtta ttgggggact attggttgct
    17041 ttactagcgc tcatttttag tatctatgtt ttatgtatca gtatcttagg tgttggccta
    17101 ttcatgatca tctcaggaat cagtgtgttt ggacaatcga ttctgagtgg attattcttt
    17161 atcggtgtcg gtctgttcgc cacaggaagc gcagtattta tttcgccact gttgctgaaa
    17221 ggaacaaaag ggctttttta tgtcatgatg aactttgtta aatggatggg acgacgtttt
    17281 attacaaaaa gagatctgca ttcagcgggc gtttgaagga ggacacataa attgagattg
    17341 aaacattttt tgattaccgg tattggtctg atgcttactg gtggcctcct agcaggtgca
    17401 acttatacat taggcgctca aaagagtctg acttgggata atggtcctcg gttgatcgat
    17461 atggttactg agacaaaaaa aatcaaggat gcaaacaaaa tcgtcatcca tgcagaaaat
    17521 caaacagttt cggtcatacg cggattggat tttgagataa aaacgactta tgataagaca
    17581 gaaaagccag aaataaagga gaaaaatggc gtgttgactg tgaatgcagt caaaaaatca
    17641 acaggtgcaa tcattagttt agaagacaca agtgcacaaa tcactattgt tgtccctgca
    17701 gatcatgaat tatctgaatt gacaatcgaa gggaataata gtgcaattga tatcaacgaa
    17761 gtatcaatca aaaaagtgaa tactaagaca catgatggct gggtatcgtt caatgaattt
    17821 acaggaggaa caataactgc gaaagatgaa ttaggctcac ttcgattaga tgaggccaat
    17881 gtggataact tgatcgtcac aggtgaaaac agcaacttcc atctagaaga cagtttgatc
    17941 agcaaagaag gaaaagtcat cctaaacggt ggcaatttat ctttgcatga gatggaaaac
    18001 agtggctata ctatccaaac gtctggtgaa tcttatattg aaaaagacta ccagccaata
    18061 acaaatactt tgttagaaca aggacagaaa aagctaaaga tcactgctaa agacacatcg
    18121 atcaatatta cgacggatca agaggacaat gaaacagatt gatcctgtac tcaactggat
    18181 attttaagaa aaaacagcaa agatccttcc aatctttgct gtttttcatc gcttaacgca
    18241 cataactata gtaaaataag aaagaaaata tctaaaaaga aaacagggtg aaagagtata
    18301 tgaaggtaga agaaggtcaa agagaaaagt taaaaacaga aatggaaaga ttacatactt
    18361 atatcactca actaagccaa accttctatg atccagacaa agaaaaagtg atggttaatt
    18421 acccgaacaa ttcagaaggt cgccaattag agcaagtgta ccatgaagtt ttcaaacatt
    18481 tattgacggt gaagaaagag ctggattatt attctttacc gattatcgat acaggaatat
    18541 tgaagtatga tgggaagaag gaacgattta tctttaaatc tgttcgggaa gatttgcctc
    18601 tttcagcagg gatggatcta gaggtcttgg tagaagacta ttttacagaa gaaaagcact
    18661 gggttcgaac aaaattggat tatttaccgc aggcagccgg agggacacag gcaagcggtt
    18721 ggtacatcac tgaagacaaa gagttagaac tagaaggtgt aatggcgcgt attcgaaaaa
    18781 aaaattaaaa aagtaacatt agatatttat tgaaggataa aggagcgcag gaagtagcat
    18841 gagagaaaaa agagcatttt atatcaatgg ttatgcaggg attgtcggat tggtcgtatt
    18901 agctttagtt ggattgtttt tcttctattt aggtatgtgg caagcgaaag tttgggcact
    18961 ttttttaagt atttttcttt ggttgatcac gttattgttg ttaagttcgg caactgtagt
    19021 cagtcctaat caagcaaaag taattttgtt ttttggacaa tatttaggta cgattcgaga
    19081 aaatggcttt ttccttacga tacctttggc acaaaaaatg actgtttcgt tgaaagttcg
    19141 gaatttcaat agttctgttt taaaagtcaa tgatttggat ggaaacccca tcgaaatctc
    19201 agcagtagta gtctttaaag tcgttgatac agcaaaggca ttattcgatg tagcgtatta
    19261 tcaagatttt gtagaaatcc aaagtgagac agccattcgg catatcgcta gccaataccc
    19321 gtatgataca ttcaatgaga atgatttgac gcttcgagga aacacgacgg cagtgtctga
    19381 cgagttgcaa aaagagctgc aagagcgttt agcagtagca ggtgtcgaag taatcgaaac
    19441 acgcttgaac catttagcct atgcaacaga aatcgctagt gccatgctcc aacgtcaaca
    19501 agcaaaagcc attttgtctg ctcgacaaac cattgttgaa ggagctgtca caatcactca
    19561 aatggcctta gagcaaatcg aagatggaca agaaatcaat ttcaccgatg atcggaaagt
    19621 ccaattgatc aataatttac ttgtctcaat cattacagac aaaggaacgc aacctgttat
    19681 caatacaggc gacatgaaag accgtaagtg acatactttt tgtaagatag gaagaaggag
    19741 tttaggacgg attattgtct tgaactcttt ttttagttgt tttaaagaaa atgacaaaat
    19801 tgaaagaaga atgatagttg attcgaaggc agaattgttc gcttttttct ataatcagta
    19861 tataaagtaa gagagaaggg gaaaaagtga aaaaacttct gatcggtcta cttgttttca
    19921 tcgttgtggt acttgcaggg gtgaaaatcg cagattacgt agttatgggt ggagaagaat
    19981 actatgtaca aattacgaca gatggtacaa aaacagtttc aaaatcagac tctggacaag
    20041 aaacagtcaa ctatagatat atcctgcctg gctatacgaa agagggtaag gaaaaagaac
    20101 tggacttcaa gggacaattg actcgaccgc ttcgtaaagg agcatattta aaaatcacct
    20161 ggaacaaaaa taaaggtgtc acttcgtatg aagaagtcga aaaaaaagac gtgccgaaaa
    20221 cagcactgga aaaactaatt aaagggtagg gaaagaaatg aacaaaatag tcgaagtaca
    20281 gaatgtaaca aaagtatacg gaaaaaacaa tgagaaaaag acgcaagcat taagcggcat
    20341 cagcttcgat gtagaaaaag gcgaatttat tgggatcatg ggcgcttctg gttctggtaa
    20401 gtcgacactt ttgaatattt tatccacatt agataaacca acagatgggc atatccgaat
    20461 caatcaaaaa gatgtgacca cattaaaagg aaatcaacta gcagattttc gtgcgaatga
    20521 gattggcttt attttccaag atttcaattt attagaaagc ttgacagcac aagaaaatat
    20581 cgctgttcct ctttctttac aaggcgtcag accaaaagaa atcaagcaac gtgtccaaaa
    20641 aattgcagaa cgtttatcca tctctcatat tttggaaagc tatccttctg agatttccgg
    20701 tggacaaaaa caacgggtcg ccgccgcacg tgcattgatc acacaaccaa cgattctatt
    20761 aggggatgag cctacaggtg cgctggattc caaaagtgcc cgggatcttt tagatacgat
    20821 ggacgaattg aatacaaaag atcatgtatc gattcttatt gtgacgcatg atccgttttc
    20881 tgcaagttat tgccaacgta ttttattcat caaggatggc ggtatccatc aagaagtgaa
    20941 acgtggagat caaagccgtg attccttcta tcgagaaata ctatctattc ttggaaactt
    21001 ggaacagtag ggggagattg actatgcttt ggaaattatc acttactggg atcaagagcc
    21061 gtttaagaga ctacttggtg ttattctcag gattagttat ggcatctgct attttttaca
    21121 tgtttgaatc aatggcaagc aacgaagctt ttttgaaaag taatacgatc gttgcggcta
    21181 cagttatcat tttccgattc ggttctgttt tactagggat catcacattc gtttatattt
    21241 tatatgcaaa ttcctttttg atgacgatgc ggcaaaaaga ctatgcaatg tttatgatgc
    21301 tgggagcaaa aggcagaaaa atcgcacaga tgattttttc tgaaacattc ttagtaggga
    21361 tcgcagctac tttagtgggt tcagctgtcg gtgtaggatt gacaagtatc gtccaccgat
    21421 tattagtgga tcagttagat ctcaatattt cgcattttac accttttagt attcacgggt
    21481 tgttgatcac tgttttgttt tttgctgttt tgtttttatt agctgctgtt gtcaatgctt
    21541 tttcgattgt caaaaaaccg attttagcat tgattcgtgc ggatcagaca ccaacaagaa
    21601 tcaagcagca taaattcttg tttttccttg aagtagtact gggaattgct tttctaggct
    21661 gcggttacta tatgatgaaa cacgtgggga cctatcaagt ctttggtata ggggtagcct
    21721 tagttacgat cgtattagga acttatttca ttttccattc tgtgatcatt ttctttttat
    21781 cattactaaa gaaatcagaa cagatttcat tgaaaaaatt gaacaatttc acattgtcac
    21841 agttaaactt tcgtattcgt gaatatacac aaatgctctc aatggtcgct atgctgtttg
    21901 ccttggcact gggcgctttg acggtaggat taggttttaa aaatgaaatt gcagacttga
    21961 cagaaaacaa ttctggatat gatctagtga tgaataatcc tcgggcagaa gatcagcaaa
    22021 aaatcaaaga actttcacca acactttctg cttcttatac tcaaaaagaa gatgcgggaa
    22081 cgatttacta taatgcaagt gaatttgcgg ctcaaccatt gatcatgata aaacatgaag
    22141 atggaacacc gccgaagatc acgaaagaaa aagttcctgc taaaaaaatg aatgaactga
    22201 ctgtacaaga ggaacttcga agctatgaat tgccggaaca gcaagaaaaa gaaatcaagg
    22261 tagtcagtca atcagaattt gatcaactga acttgccaca atccacttta cagctagttc
    22321 aggtaaaaga cttccaagca aacctgaaac caatcgaaac acttgttgct caaaataaaa
    22381 tgaacaatcc atctttgcaa aaagtagagt acagcaacca gaaatatgaa atgtatgaag
    22441 tgtataatgg tctattctct ggttttgaat ttatgggatt cttcctaggt ttagctttct
    22501 tgaccatgct tgctagctgt ttgatgttca agatcttgtc aggaagcaag agtgacattg
    22561 ctcgttatga aatgcttgaa aagataggaa cacgacgcgg gttgcttaaa caatcgatcc
    22621 gtagagaagt aggcgtgtta ttcttagcac caggaatctt aggtgtagtc catgtcttat
    22681 tcggattaca aatgtttggt ctattcatgc aaaatccata caaagatatt tgggttccgt
    22741 ttacgatatt cttcgtattg tatttcatct actatgtact gacgacatgg ttatatactg
    22801 gaatcgtatt gaaaaagaga ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc
    22861 aagcaaaaat agctcctcat atttttcgtt tggttgggct tattaccgca gatgcaagct
    22921 tttgaacacc gtttgttcgg aaaaagaggt tgtgacaata tttttgtcac aacctttttt
    22981 tcacggtctt ttattagaat atagtaaatt ttttctcgtt actcacggaa taagctgtta
    23041 agaaaacggt ttccatgtat actggaatca gtgcaaatga aagaaaagag ggtgcaagga
    23101 acatggaaat caatgaacaa aattttggcg aaaactatca cttgattacg atcacgaatc
    23161 aaaatgggac atctttgtct gtcagtgatc ttggggcacg ggttgttcat tttcaaacaa
    23221 taatcgataa tgaaaaacga gagttgatct taggttttga tgaagcaaaa gaatatctag
    23281 aaaaagaccc ttatatcggt gcttcaatcg gacgtatggc tggacggatt acgaatggca
    23341 cattcaaatt agatgatgaa acgttcgaag taaaaacaga cccggacact ggtcattgtt
    23401 tacatggtgg tgcacctagc tttgaagcca agcagtggca ttatacagtc atcaatggtg
    23461 aaaacgaagc atcggtcatt ttctatcaga ctagcccaga tatggaaaac ggatttcctg
    23521 gaactttaga tgtagaagta cggtatacgc tgacgaacga tgatacatgg cgagtgacgg
    23581 tccaagggat cagtgaccgc aaaacagtat tcaatcctac aaatcatgtc tatttcaatt
    23641 taaccggtga tccagcacag tcaatcgacg aacatatact ttggttgaat agccgattat
    23701 ttgctacgct caataaagat acaacgccta caggagaagt agtttcagta agtggcacag
    23761 catttgactt ccaacgtcct aaaaaattag gtgaggtctt tgccagtgat tttcgccaat
    23821 caatgatagt gggcggcatc gatcatccat ttttgttgaa aaaacaatct ggtttactaa
    23881 atgctgcgga attgacaagc ccagatgaaa aagtatcgat ccaagtaaaa acagatgctt
    23941 caggaatcgt gatttttaca gcaaattttg gagaagatgg accggaaatg cgcgggaata
    24001 aattagtaaa tcatggcggt atcacatttg agactcaaga actgccagga gcggagcgac
    24061 ttgaaagttt tggagatgtc actctggaac ctaaccaagt acgcgagttt gtaacggaat
    24121 acaaaataaa tataaagaaa tagaataaat taaaaaggga gtgtgacagt gtcacatccc
    24181 ctttttaatt tattctattt ctttaaaggc agatcaagcc agaatgattt gtctaaactt
    24241 aacaaggtta gtacaggaac agttgcagct ttaactgtac gagtagttgt ttctggtatc
    24301 tgtcttgccg taaaattgtt ccacaaatcc cagattgaag cgacacggaa gatggaagaa
    24361 gcgttgttga cgcgttttat cgttgaaaat tctaatcctg tgattggcac gccatctgtt
    24421 gtccatttga ttggcacatc gaatcgctta gacatattga ggatttcagc gtttgcttct
    24481 tcagttgttg ctgcttcttt tttcggttca tcatattttg tcaggtcgta cgcttcgatg
    24541 atcgcgttca atttttgtga atattggcga tctgtagcat aacgtccttc caaatatttg
    24601 gttgcttctt tgtagtcttt tgtttccgac ttccaagttg gtttgtagaa atcaggattg
    24661 ccagtcagtc catttttgat caagtcggca tagtcttcca aactttcctt gtaagaagga
    24721 tatttacgga attgtgcgcg gatttggtag ctttgtccgg aactatcttg ttcaagtgta
    24781 ttgaaggtca cgctgcttcc tttatatgat cctttgatac caaaaaggtt atgatttggt
    24841 tcgcttgata ataagctgtt tccagatcca ctttcaagga tagcttgagc catcatgact
    24901 gatgcgtaga ttccttcttt ttgcccgatt tcctgtgcat catctgcaat ctttttcaag
    24961 aactgatcag ttgtttggtt ttgactgaaa tggaacgagc catctaatcc atctaaaata
    25021 gatgagccgc ctgtcagcga acctgaagca gcaggtaaac ctgctaagtt tactcggaca
    25081 gcaaaatcag gcgtgaaatc tgaaatagaa gttactcgaa ctttatctcc tggttgaggc
    25141 gcatggataa attgtccgtt cccaatatag atacctacat ggtgagtaac accggaagaa
    25201 ggtccccaga agacgaggtc gccaggttgg gcctgactta ctggaatctg cgtacctgca
    25261 tattgctgtt cgcctgtcca gccaccgata taatgaccgg ttgctttcat atatacgtaa
    25321 taagtcaaac cagaacagtc aaaagtattt ggaccttttg ctccccatac atatggtttt
    25381 ccaagatgct tgaatgcttc tcgaacgatt gcttgttgga cattcgttgt atttgtaggc
    25441 aatacagcat caattggtga ttttacaaca aaatcagaag aagcagaaga tggattctct
    25501 ataccgcttt gatttgctgt atttggacga gatgaagcat tgttcgttcc gccattcgat
    25561 gaaccattgt ttggatggtt tggttctctc tgagtatttc cattgttatt cgatccagat
    25621 gggtttgttt gattcgaaga attcccgctg ttcgaattat tgttattatt gtttgaatta
    25681 tttgaaccat tattattgtt gttattaccc acatctggtt tgtttggcgt ttccggatct
    25741 ggtgtactag ggacttcttc actaggatca gttggtttct ctgttgaagt atccggtcca
    25801 gctttaaatt ctgcagtaat agataaattg ttcgtaccta ctgtaaaggt ctttgcatca
    25861 taatttactt ctttggcacc attaacagcg actgaagcaa tttgttcacc ttcagctggc
    25921 gtaatagtgt aagttacctt cgtttccgct aataaacctt ctaccgttcc actttccgta
    25981 atatccaaag gttgctgttc aggggaatcc gctgtcgaag cagtcagttg gatcttacca
    26041 atcaaagaag gagcaattgt aagggaatat gtctcggctg gcttttcatt ttctgatgga
    26101 tcagccggat caatttcagt tggctcggtc gatcctgttg ttgagttagt tgttccagtt
    26161 gggtcttctg taaaagaatc cgttgtttca ctagtagctg agctggatgt agtcgtatct
    26221 gttgtgactg tttgatcagc tatttgatta tctacggcaa atacggtatt ggtcgacaaa
    26281 acagacggag caatcagcca agtagcagct agcaaacgta tcgttttttt atttttcata
    26341 ataaactagt ccttttcctt tcattgattt tctgtcttat tcagcattca ttagacattt
    26401 tttggaacag ataatcgtgt cgaaaagctt tttcttttca taaatctgtc tgtgtattct
    26461 aaataaaaca atttgtaaat aagcaacgag cattcattcg tttttctttg acgttcattt
    26521 tattgcatag accacctttg tttggggata aacaagtggg gataaaaatg gttatgcata
    26581 tgtaaattat accaaagttt ggaaagtatc acaaaaattt ataaaaataa tgatcctaaa
    26641 aagaaaaaga ctgaaatatg tgataaacat ctcatacttc agtctttttc attaactatt
    26701 cataagacat taggtcttca tcaaacccgc taacgagagt agtgatcatt gctacgacta
    26761 gactaacagc cagtcctgct aagtaccaga aaaaagtacc ggaaatgaat gcaggcaatg
    26821 tggtcagact accaaataca aaagcgatcg ctttcacttg ggcaaatccc attacagctc
    26881 caccagcagc tgcaccaatg caagcagcaa caaatggttt tttcaatggg atcgcaattc
    26941 cgtaaacagt tggttcggtc actcccgcaa gtaaaatcga agcaaaagca gaaccggaga
    27001 tcgaacgggt ttttgaacgt ttacttcgca gaaatacacc taaagctgca ccagccattc
    27061 caaaattggc tgctcctgtc aacggaacga ttcggtcgaa cccataagca gagatattac
    27121 tgatcatgac agggtttaca gcccattgga taccaaatat taccaaaata ttccaaccac
    27181 cagcgatgat tgcgccactg atcggtccgt taatatccat catccaagta attgcggcag
    27241 ctaaaccttc gccaaggtaa acacccgcag gcccgaatac cattaacgtc aaaggaaccg
    27301 tgataactaa tgaaagtaaa ggtacaaata ctaattgcat attttcgcga atatattttt
    27361 tgaggaattt ttcaacaaaa gaataaaaga aaatacctaa aatcgccggc atgacagtag
    27421 acgtatactg catcagtact acaggaatcc ccagaaaatc agtagctgct ttgctactgt
    27481 ctgaaagtaa agaggtcaga ttcggttcaa tcagtgctgc agcaatgaca gccgcaatat
    27541 atccattcac tttaaacgtt ttggcagcag aaaaagcaag aaagattggc agaaaataaa
    27601 agacggcatt cgacgcagca gacaaaatat gataagttcc gcttgtttca ctaagccagc
    27661 caatcgtagt cgctaaaaca accagacctt ttaatatacc agaaccggca aacagcggaa
    27721 tgatcggcgt aaagatttcc gatatcaaac caaatagttt ttcgatcgga tttagctttt
    27781 ctttcggagc tgaatgatcg atttgacgcg tcaattcctt gtaagcagga gccaatccct
    27841 gatccatgat tatttctgca tatctatcga gtaaaatgaa atacttaatg gaagggattt
    27901 gctgttttaa tttttctgca ttggctactg gctgtttttt caatttgata cgaagccgag
    27961 tcgcacatgg aaggacagaa tcaatattgt cttttcctcc caactgttca atcagcatat
    28021 gaatctgctc ggacagtacc atctgttcag gattcattgt cgtttccatt agaagaccac
    28081 tccactcact aatataatat tggcgtaagg tgtcatttcg cctgtacgaa taaatgcatg
    28141 acagttattc aactcttttt tcatttcttc atgtgggata aagctaatcg gtgtatctgg
    28201 taacaataat ttgatttttt ccaatatttc cgggttcatt gtctttattt cttccgccaa
    28261 ttcaatcgat tgtacctcaa gttcttctaa aacgttttct aaaacagata aaaaacttgg
    28321 aagaccgttt gagacagcca aatctatttt ttcagtacca aaggggacag gcatgcctgc
    28381 atccccgata cttaatttat caaagtgccc catttgtgcg attactcgtg aaatatctga
    28441 attgattact tttccttttt tcatgtttgt ttcttcctct cattgttaat tttagactgc
    28501 tgattgttct aaagcttcgc ggtaagggat agaaggttgc gcaccataag actgcacagc
    28561 aacagaagag gctagatttc cataaaggat cgcttctttc aagttactaa ggtctggctg
    28621 aagtgtgctg cttaatgcgc caataaatgt atcacctgcg gctgttgtgt caacggcatc
    28681 cactttaaaa gcagggacga taccgtgttc tttttctgta tgatagaaag cgccggcact
    28741 gcctagtgta atgattactg ttccaatacc taattcatgg agtttttcgg ctgctgcgac
    28801 caaactgtta tgatctgtca ctctgattcc tgtaatgatt tctgtttctg tttcatttgg
    28861 tataatgata tctgtctttt caagtagttc agtaggaatc gtttcacgag ctggtgcagg
    28921 attcaggatc gttgtttttc ctgcgtcttt tgcaatagaa aaagctagga tcgtcgcatc
    28981 taagctactt tcaaactgag caataataaa gtcactgttt gtaatcagtt gcttgttttt
    29041 taggacttct tgttcatgga aagcattatt tgcccctgca tggatcaaga tactattttc
    29101 tcctgctgcg tctaccataa tcattgcttg tccggttgtg gcgccttgga tttcagctat
    29161 cccagatgta tcgatgtttt cttttgtcag tagatctaat aactgttgtc cttcgctgtc
    29221 agccccaacg cctccaataa aagatgtccg tgcgcctgaa cgtttggctg ccactgcttg
    29281 gttggcacct ttacctccgc cagcgtgaaa aatctcatgc gcatgcatcg tttcgcctgg
    29341 cttgggcatg ttggttaaac gaagggtagt gtccatatta atacttccaa ttactgtaac
    29401 cgtgttcatt ttacaaacct ccaactatct catttatttt gatgggaaaa ttatttttta
    29461 aaacgtttta gtaaaacgtt ttaatagttc gataaaaata tagcacacct tgaaagctat
    29521 ttcaagggtg cagttgaaaa tcttttttct aatcgtacag gtaatctttt ttcttcccat
    29581 tctttttctg ggaattggat ccgatctaac aataacttgg cagatgtttg tcccaattcg
    29641 aagattggtt gtgcgatcgt tgtcagtttc ggcttgatat actcgcacat atctatatta
    29701 tcatagccaa taatgctgta gtcttcaggg atgctttttc cagcttcctc taatccgcga
    29761 tataatccaa aagctaattc atcatttaaa gcaaacacac cagttgcagc agaatcaaga
    29821 agttctgctg tgatctggta gccaccttgt tttgagaact gtgtaggtaa gaggatcagt
    29881 tggtcgtgag ggatttggta aacatcaaga gcagatttaa acccctcaat ccgagcgtgg
    29941 acattttccg gtggattttc aggatagaca agggcgatcg tttgatgtcc tagactaagc
    30001 aagtgcatgc ccgctaggta accaccgcga aaatcgtctg ttcgtacggc atcactaaat
    30061 ccttcagatt ttttctgatc caaaacaatg aagggccggc cttgtttttt caaattttcg
    30121 ttgattgcat ctgtagagac agcagaagtc gcgataatga atccatccac acctcgacgt
    30181 gtgagctcgg ctagatattc gatttctttt tgatgatcag aatcagcatt acataatatc
    30241 gtgacgaaat tctgcttata caagatatcc tcaattcctc gcatcagtgt actgaagaat
    30301 ggattcgtga tatcaggaac gagtacacca attgttttcg tttccttggt aatcatttgt
    30361 ctagcaaaat agtcaggctg atagcctaat tcttctttgg cagctaaaac tttctgaaca
    30421 gttttcggac tgaatttctc cgtatttcca tttaatatca aggagacagt tgtgattgaa
    30481 acgccggaaa gtttagcgac ttctttgatt gtgatctttt ttttcaccat gttcatactc
    30541 ctatctaaat cctgtggtta ttttcccatg aaatcaaaaa gaagtaaatg aaaatcacgt
    30601 gtgccagtac ttatttgctt tgttggatag cttcgattat ttgtttcgtt gagcgtactc
    30661 gtgcagtttt cggaaatatc ttttttatga acaattgatg ggattctttg tcacgatcac
    30721 tgcaagcatc ttcagcaagc acgatatggt acccgtgttg aaaggcatct aatgcagtag
    30781 catatacacc gtttgttgtc gctacaccgc ttaaaatgat agtttcgatt ccacgccggc
    30841 gaagttgaag atcaagagaa gtaccaaaaa aagcacttgg attgtatttt gtgatagtca
    30901 acatattatc tgtatctttc aaagaatcct tcaaaagtaa atcagtgaat tctggaggta
    30961 cagaagcagt cattccaccc atatcagttt gttgactcaa ataagggaaa gtggagatgt
    31021 ctacgttcac taaaactttc aaggcagcgg tacgtttcaa tgttcttact aacaaatcat
    31081 tgtttgtcag aatagatgct gcagtgtgtg gagagagtgt accgttattt acgatctctt
    31141 tttgcatgtc gatcgcgaca aaagcagttt ttgataaatc aaaaatcata ttttccttta
    31201 aatcattcat gatgttcctt ctttcaaata acaatgtttt ttatgtaagt aaatcataaa
    31261 tcgtttattt gtcaactaaa ttaaaggatt cctttcttta gtctagagaa attcagtggt
    31321 aaaataaata agtgtgagaa aacgcattcg atgcatagat atagcgagaa atatcgtgaa
    31381 aatggaggaa tcagagtgaa gtatgtcgaa gtaaaaaatg aatacaaacg atacaaaatg
    31441 ggagaaacga ccattacagc aaatgacgat atttcttttt caattgaaaa aggcgaatta
    31501 gtgattatac ttggtccaag tggagcagga aagtcaacga ttcttaatat tttaggtggg
    31561 atggatacac ctgatgaagg tcagatcatt attgatgaca cagatattgc gcaattttca
    31621 gataaacagc ttactgctta ccgacgaaca gatgtagggt tcgttttcca attctacaat
    31681 ctcgttccta atctaacagc aaaagaaaat gtggaattgg caacggaagt ttctcctgat
    31741 gcgcttgatc ctgtagaggt attgaggcaa gtgggcctag ctcatcgatt gaataacttt
    31801 ccgtcccaat tatcaggagg cgaacagcag agggtttcaa ttgctcgtgc actagctaaa
    31861 aatcccaaac ttcttttatg tgatgaaccg acaggcgcgc tggattttga aacgggcaag
    31921 caagtattga aattattgca aaacgctagc agacaacacg gcaataccgt tttgatcatt
    31981 acacataatt ctgctttagc gcccatcgct gatagagtca ttcacattaa tgatgctaaa
    32041 gtaaggtctg ttgaattaaa tgatcatcct tcatccattg atgagattgt atggtagggg
    32101 gattttatga aaacaagaac atatcttaaa gcaggttttc gcgaaattcg gcaatctaaa
    32161 ggacgattca ttgcaatcat ccttattgtc atgctaggaa cacttttatt tgtaggtgtc
    32221 aaaactgctg gacctgtcat gcaaaaaacg atggatcact atgttggtac agcaggactt
    32281 tctgatttgc aaatcgtttc tactggtggc ttgacacaaa aagatattgc tcaagcagaa
    32341 aagatcccag atgcaaaagt agaaacagga aaacagatct attattccaa tactggcaaa
    32401 aacgaagtga ttcaaatatt ttcttataac aaaaataaca agcagaacaa gctacaatta
    32461 actgatggaa aactcccgga aaaaccaaac cagcttgtat tggatgaaaa agcggaagat
    32521 gaagggtata aaatcggtga tatttatcag attgattcag atgaattgaa agaaaaagag
    32581 tataccatca cgggctttgt ccgttctcca ttgttcatca acaatttgga gagaggatac
    32641 gcgaacgtcg gaaatggtag cgtcgattat tttgtctatt tacctgaatc cgtttttaaa
    32701 acagatattt attctgtctt atatcttgat tttacaaacg taaagaattt gaatacgtac
    32761 agcaaagctt acaaagataa aatggagcaa aatcaagaaa aggcagaaaa gtatttacaa
    32821 gatcgacccg aagaacgctt agaagagctg aaaaaatcgg ccaacgaaga attagaaccg
    32881 gcacagcaaa aaatagcgga tggcaaagca caaacaacgc aagcaagaac acggttagaa
    32941 gatgctaaaa aacagttagc gcaacagtca gcaactatcc agcagcttcc tgaagcgcaa
    33001 cgaacaatcg ctgttcaaac attatctcaa caagaagctc aacttgctga acaagaaagg
    33061 caattagttg agaaagaacg tgaactggcc tctgcagagg aagaattgaa tcgaaatgca
    33121 gaaaaaattg aaaatttaac taaaccatca tacctataca atgaacgttc agaaaatgtc
    33181 ggttttcaag aatttggtga tctgtctgat cgtatcgctg cgattgccaa tgtttttcct
    33241 gttttctttt tctttattgc cgcattgatc acctttacga caatgacacg tatggtagaa
    33301 gaaaaccgca gggaaatcgg gacattaaag gcgttaggtt atacgaaagt tgaaatcgca
    33361 aaaaaatatg caatctatgc aagtctagcc tcagggatag gtattgtttt aggaacgata
    33421 ttaggaacga atcttttgcc aaggatcatt tttgagctgt ctaacgagcg gtatgatatt
    33481 gggagtgcgc ttatttttta tgactggccg ccgattttac aagcagctgc cgcattcttc
    33541 attgccgcat ttggcgctgc aatgatcgtt ttattcaaag atttaagaga acggcctgct
    33601 gcattgcttc aaccgaaagc accgaagcca gggaaacgca tttttcttga atacatcact
    33661 ccgctgtggt cacgccttag ctttaatcaa aaaatcagtt accgaaatct cttccgatat
    33721 aagtcaagaa tgcttatggc gattatcgga attgctggat gtgccgggct gatggttgca
    33781 ggcgtgggat tgaaagattc tctaagttct gtttcagcca aacaatttgg accgatcatt
    33841 gactatcaag caatcgttac attggattca tccacggaag atagtcgtca aaaagcagcg
    33901 gatatgctgc agaagcaaga aaaagtaaat gagatcctag ctattcatac tcaaaccgta
    33961 gaattgagaa aaaaaggaca tgcttcgcaa agtctgacag tgatcgtacc aagtaaaaca
    34021 gctgatttgg atcgttttat ccatttaact gatcttgaag agaacccacg ctccttgcct
    34081 aaaacaggaa tcgctattac gcaaaaagta gcagaactat ttgacttatc tacaggagat
    34141 catatttcgc tttatgatga agatcaaaaa gaatggaaag tcgaagtaaa agaaatcgtg
    34201 aaaaactatc taggtagctt tatttatatg tcccctgaat attatgcttc agttactgat
    34261 caatcgatga tggataatgc atttttgctg cgtacagata agatgacaac aaaagaagaa
    34321 gaaatgcttt ccgagaaact gcttgccaca gacgctgtga caaatacgtc tttcatgtcc
    34381 aaacaaatcg aaacgcaaga agaatcaatg gcgaacttag actcggttgt cttaatcttt
    34441 gtcgtattat caggactgct ggcttttatc gtcttgtata atctaactaa tatcaatatt
    34501 tccgagcgtg tacgcgaatt atctacaata aaagtccttg gattttttga taaagaagtc
    34561 acgatgtaca ttgttcgaga aaatatcatc tttactcttt taggaatcat cggaggattt
    34621 ggtgtaggat atatattgac tgacttcatc ttgcaacaag cgtctatgga gaatgtcatc
    34681 tttccattag tgatcacatg gtgggcttat gtcttatcag caggattaac tatcgtattt
    34741 acggttattg tgatgattgt tacccatttc aaattaaagc atatcgatat gattgatgcg
    34801 ttgaaatcga atgaataaaa acagaggttg tgaaatcagc ggtttgacct gagtattaga
    34861 gaaacaaacg gcaaaatagt ttttcatatt ttgccgtttt ttgagctaat accgaaggac
    34921 agctgattga acaccatgaa tcagaggttg taaaaaagcc gtcctgcatc gagcaaaaag
    34981 aatactcaaa taaaattagc tcctcatgtt ttacatttga gaagactgat tgccgtagat
    35041 aaaagctttt gaacaccatt tatagaagaa acaagaatat tttgctattt taaacaagag
    35101 gatagacaaa tacatgtctg atctcttgtt ttttattggg caacagacct cttagaatgt
    35161 ataaagataa attttacaaa cgctttcggt tcagttataa taataaatga taacttgtat
    35221 atataagttg tggtaggtaa taaatcagtt gaatggaggt aaatatccat gacatttaaa
    35281 gacaaagtca tttaccaaat ctatcccaaa tcttacaaag acagtaatgg tgatggaatt
    35341 ggagatttaa aaggaatcaa agaaaaactc ccgtatctga atgatctagg catcgacatg
    35401 atttggctaa accctattta tccaagccct caaaaagaca acggttatga tatctctgat
    35461 tacacagcca tcgatcctat ctttggtacg atggaggaat tcgaacagct aatagccgaa
    35521 gcaaagaaat accggataga aatcatgctc gatatggtgc tgaatcacgt ttcgacagaa
    35581 catgaatggt tcaaaaaagc actagcaggg gaccagcatt atcaggactt cttcatttta
    35641 agagaagagc caacggattg ggtatcaaaa tttggtggaa gtgcttggtc gccatttgga
    35701 gatacgggga aatattattt gcacttatat gatcggacac aagctgactt gaactggcgg
    35761 aaccaagcag taagagagga actattcaaa gttgttcgtt tttggatgga aaaaggggta
    35821 aaaggattcc gtttcgatgt tatcaatgtt atcggtaaag acgaacaatt gaaaaataat
    35881 aaagaaaatg atggcaaacc tgaatatacg gacaaaccaa tcacccatac gtatctaaaa
    35941 gaattgaacc aagcaacgtt tgggacggat tccactatca tcacagtcgg tgaaatgagc
    36001 tctacgacga tcgaaaattg tatcttgtat acagaaccta gtagagaaga attatcaatg
    36061 gtctttaatt tccatcattt gaaagtcgat tatgaaaatg ggaataaatg gtctactcct
    36121 ccatttgatt ttgcagaatt aaagcgacta tttcatacat ggggagaaaa gatgagtgag
    36181 ggtaacggct ggaatgctct attttttaat aatcatgatc agccacgtgc gctcaatcga
    36241 tttgtagcta tcgatcagta tcgaaaacaa ggagcagaga tgctagcaac catgatccat
    36301 ttgaaccgtg ggacgcccta tatttatatg ggagaagaaa tcggcatgat cgacccagac
    36361 tattcatcga tttccgacta tattgacgta gaaagtttga atgcttataa gttactcctt
    36421 gaacaaggat tcacagaaaa agaagcgttt cgtcggatca aagcaaaatc tcgcgataac
    36481 tctcgaacac ccatgcaatg gtcagacaca gaacaagcag gatttactac agggaaacct
    36541 tggttaaaag ttggaggcaa gctagaagag attaatgtag aaaaagaact atcttctgaa
    36601 gattctattt tgtcctatta caagaaattg attcggctga gaaaaacata tccaatcgtt
    36661 gcacaaggag attatcatgc ttatgaagca aatcatccgg aagtttatgg ctttcttcgc
    36721 caatttgaag gacagcagct gcttgtatta acaaatttct atgataaaga tacaaggatc
    36781 gccatcccag aaggattcac agaagccaat attcttatcg ataattattc cgatactgtt
    36841 cttcatcaaa gtctggagct aaaaccatac caggcaattg ctttgctgaa aaattaaaac
    36901 aaaaacacaa aacgtcgttc ctacgagcta ttctcgtaag atcgacgttt tgtgttttat
    36961 ttaaaataat cttcttcaga aaatgaagag ttttcatact ctcctttatc gccataaaat
    37021 ttattgtagc gttgtttgaa tttacggaaa ataaaagtaa cgagtaattt gactaacgta
    37081 tagataggaa taccaaaaat aacgcccaca attcccatta gatcacccat gacaagtaaa
    37141 acgattaaga tcgtaatcgg atggatctgt aaacgatcac ccattactcg aggaatcacc
    37201 aagtcaccgt ggagaagttg tacggcaaac cagacaatga caaatttgac agccataaaa
    37261 gtagagtctt ggaatgcaat gatcaaacct ggaaagaagg cgataaacgg cccaatatat
    37321 ggaatgatac ataacaaccc agcagaaata gctaaaacac tagcaaattc taatccgatc
    37381 agtaagaaac aaacccagta gactgctcca aggataaatg aagcaatgat ttgccccttt
    37441 agaaatgaac ccaattgttg attagcaatc tttgtcaaat ttttaaaatc tgtacgaaat
    37501 gctggtggga caatcgctaa aactgactga taaaattttt gaggatctct caaaaggaaa
    37561 aaagcgacaa ttggaccagt aaataaagta ataaaaatag ctgtaacagt tgaaaaaatg
    37621 ttgctgatcc gttgtgcgcc actttcccaa taatttccaa taaatccagc tatatcagac
    37681 gtcacgtcgt caatagaagc gaaaaattga ttaaatgaat cggcaaaagg tgttttctcc
    37741 aaaaattgtc ggagactctc ttgaaaatct tgaaacaaat ctggcaaact actgatcaat
    37801 gtctttgcct gttcttcaag aaaaggaata agccatatgc ttccaagccc caataaaaat
    37861 aaaataatca cataaacgat aatgactgac aagttcctcg aaaggtgctt gctcaaacgt
    37921 ttgatgactg gttccaaaag ataatacaag atcagtgcaa acaataatgg gggcaagata
    37981 gtagcgataa tgattccgac aggcttgaat ataaacgaga tctgatggaa aaaataaatg
    38041 atcagcgcaa gtaagataac tattcctaaa acatagtaag aggtttttcc tcctaaaaag
    38101 cggatcaaac gattcgttgt atctgtttct tttttcactc tttttcctcc tttatctata
    38161 aattcattat agacaaaagc gggtataaaa ggaaaatgat agaggttgat tgcaaaaata
    38221 tcgtcaatca ttcatataaa ctttctcatc aattaaaata agaaaacgct tgacagttct
    38281 tttaaccata tgataaatta aatcctgttg ctaaaacgta actattacgg tttgcgaaaa
    38341 gcgaatcgga acattcaaat gaaagaagat gagaagagga gtgtcataaa tgaaacgatt
    38401 gataggtata ttggccatgc tggttttagc aggtatgtta actgcttgcg gggcaagtgg
    38461 gaaagccgag gacagtaaag aaaaattgag cgtgatgacg accttttatc ccatgtatga
    38521 ttttacaaaa gcaatcgtcg gggatgaagg agaagtagag ttattgattc cagcagggac
    38581 tgattcccac gattatgaac cttctgctaa agacatggca aagatccaag atacagatat
    38641 ctttgtttat aatgatgaaa acatggaaac atgggtcccc gcaatccaaa aaacattaca
    38701 agaaggcaat gtccatacga taaaagcgac agaaggtatg cttttacttc cgggaagtga
    38761 agaaggacat gatcatgacc atgaacacgg ggaagaaggc catacacatg agctagaccc
    38821 acatgtatgg ctagctccaa gtttagcaat caagcaggta gcaaacatac gtgatcagct
    38881 gattgaagct tacccagaaa aacaggaagt atggacaaaa aatgcagcag cctataccga
    38941 gaaacttcaa gcactccatc agctttatca agaaaccttt aagcaagcaa aacaaagatc
    39001 ttttgtcacg caacatgctg cattcaacta tctagcgtta gaatatggat tgaatcaagt
    39061 atcgattgct ggtctttctt ctagtgaaga accgtctgcg gcgagaattg ctgaactgaa
    39121 acactttgtt aaagaacatg gaatcaacta tatttatttt gaagaaaacg ccaaagatag
    39181 tattgccaga acgttagcaa acgaagcagg tgtatcttta gaagtattga atcctttgga
    39241 aggattgacg aatgaacaaa tagaaaatgg agaaaactat ctttctatca tggaagcaaa
    39301 cctcgaagcg ttgaaaaaaa cgacagagac agaaaacccg ctagaagata ctttgacccc
    39361 caaaaaagaa aagagcgtct acaacggtta ttttgaagac gaggatgtac aagatcgctc
    39421 tctttcagat tgggcaggaa cttggcaaac agtagatacg tatgtagaag atgggacttt
    39481 tgatcctgtt tttgaatata aagaaaaatt gaatcaggat aagacagcac aagaatataa
    39541 agaatattat acgaagggct atcaaacaga tattgcttca atcaagatca gtgagaaaga
    39601 gatggcattt acgtttaaga atggaacaac gaaacgttca aattatcgtt atgtagggaa
    39661 agaaatcttg acctacgagg caggaaaccg tggcgtaagg tatctattcg aagcagaaga
    39721 taaggaaagt ggcgctttta gatatattca attcagtgat cacacgattg caccggctga
    39781 ctccgaacat tttcatttat atgcaggaaa tgaaagtcaa gaagtattgc tgaaagaaat
    39841 ggagaattgg ccaacatttt atccagatac aatggatgga cgtgaaattg cacaggaaat
    39901 gcttttgcac tgataggcaa aaaagaaccg aagggtttgg atcggctggt catttagtcg
    39961 gtccaaacta ttcggttctt tttatgaaat caatttcttt aatccacgga tagaggctgg
    40021 gatggtctcg ccgtttgcca acgtgacttc tctggttttt ttattaatcg accgcacatt
    40081 ttgtgtattg ataacatagg atttatgaca acggataaaa ttccgatgca ttttctcgat
    40141 ttctttgatc ttctcataga attgtaattg ggcatgagtc aaatggactt ccagtttatg
    40201 tggcgctcct agcgaagtag aaaaatattg gatgtctttg atcggtaaaa atttgatctc
    40261 atcattaaac tctattttga agatatcttt ttggatttgg gacatttgaa aatcttcgaa
    40321 aattttgctc aggatatgct cgacattttc ttttaaatca taaagatctt ctttgacgat
    40381 ataatcagtc ggttcgatgt tgctttttaa gattttcatc gacatttccg tatgggaagt
    40441 cacatagatt atttttccta aaggatctaa ttcacggatc aatttaccga tcgctacacc
    40501 atccatttca ctgtcttcta gttcgatatc taaaaagtaa ataccaaaag aagaagttct
    40561 gatcttggct gcattgagaa gttcttccgg atcagaggta gaaatatgga cataactgtc
    40621 taagttttca atcatgattc tatttttgat caccgttgat aaaacttcta attgttttgg
    40681 atcgtcttca caaatataaa tgggaatcat atcattactc ctttatttta tttgtatata
    40741 aatcgtttga gaaaaacgct ggttttcaat tgatgtttca aggaaaagat aaggattggt
    40801 ctttgtcaat tcatccaaga taaacaagcc aaggccttcg ttttttggat ttgtttttgt
    40861 tgagaaccct ttttgtttca actggtttaa cggtaatgta tttgttgttg tattgatcac
    40921 acgaatcatc acggaatgat tcttcttgag tatggtcaat tcgatttttt tcttctttgc
    40981 agcactagct ccttcaatcg cattgtccaa gataatacca agcatacgta caaggtttac
    41041 cgtatgtttc gtatccagtt cgattggctc aggaaaatga agctggacga tcaacccttt
    41101 ttcctgtgcc atcatgagtt ttaatgacag taaactacgg atctcaggaa ctttcatatt
    41161 atccaacata cttagattgg ccggaaaaag gttcatcatc tggcgtgtag gtaatatcgt
    41221 ttgatcataa taagaccgta atccttctaa gtcgccttct gaaatatagc tgtgaagaga
    41281 aaaaagcaga ttttggtaat catgtttgaa ttctctcaag tcttgatagt ttttttctag
    41341 atctttgata taatcctgtt gcatcctgac ttgttgctct aataactgat cagctaattt
    41401 cttattagag attttccaat aataaaccaa gatgatcagg gcaacacaca gatatagaat
    41461 gaaaaaactc gtattcaaag ctaagacatc aggtgtttca ccagaaaaac gggtataaaa
    41521 aataatgata tagtatgtaa ataatatcaa tgtcccgatc gtaccgatca tacggcggtc
    41581 cacagtgtga aaccaagtct ctaacgattt ttttaaacaa aaagctaata aagcagataa
    41641 aaaagcggat aagacaatgt gaaaatactg caatgaatct cctggttcaa taaccgaaga
    41701 tttcaaaaca aaaaaatcgc cgatgcttgt taagtgatct cctaaaagcg acgtcaataa
    41761 cccaaaagga agcgcgtaaa ccaattgttg acgcgaagtc gaaaagaaga aaaaagtaag
    41821 catcagcatt cctatagcaa ttagagcagt aaaaatccct aaaatcgaat agacccatcc
    41881 aatcaaaata caagaaatca gaatgactcc cgcaaacaga tatttgtatc ggatgtgatg
    41941 gtcaatcaat aagatacaaa ttgtgtaaat caaatattgc aacgctatgg accataaaaa
    42001 cataaagtac agctcccatt gatttttacc aaattatagc acaattggcg tattattttt
    42061 ttaatttttc agggattttg aattcagaac tcataccaaa gcagcagcca gatacaaaaa
    42121 agtcagataa gttagttaat tgtttaatga ttgttttttt catgaaagat tcctccaaaa
    42181 ttcatcaagt agtttgtaat aggaagcaac gtagctattt ctaaaacaat cccaagtagc
    42241 aaataggtag aaaagtaaga agctgagaaa aataacgtaa tgagagaaaa aattagaaac
    42301 atgctgatcg ccttctttaa taatggggga cgtttctcgg gttcaatggg attgattgct
    42361 gtacctcttg atccatagcg aagcagtaac aaaaagcagc tgattaacaa aaagaccatc
    42421 attgggaagg agatagtcaa ttgcagatgt ttcatcacca agggaacgcc ccataaataa
    42481 agtagtgtcc acagcagaca aacgaattca gagtcggaat gcaatccata agcatatctg
    42541 cggatgcaga tataagaaag aaaggtgatt cctgtttccg cccatgagcc tgtcaccaga
    42601 gaaaagacta gaacgaccgc tagttttcca agattattca ataaaacttc taagacaaat
    42661 tttacttgga catacaccat atcttcttcc gatttgtctc cgctgaataa ggcttctaat
    42721 aatttgttca caactttatc tttcatctca tacgtacctc caccacaaat tttatgctaa
    42781 aaaaaataaa aaacgtcttt tgtttcataa aaagtggttt tgacatcaaa accgtcatga
    42841 tctcctaaaa aaatcttcgt tttccaagaa ccttaccaaa aaaagtgaca gttttgatac
    42901 gaaaagtact ttttatgaca agtttgtgct ttttcgagtg atttatgtta aaaaattact
    42961 gaccttataa aaggtgatgg agggattctt atggaaaatg aacaattgtt tgaagtcggc
    43021 gaaacatatg catttaaatc tgatttattt gaatcaccaa taaaaggaaa aatagaaaaa
    43081 atctatgaaa atagtgtgat gatacgtgtc atgaaatgcg cagtagaaga caatgatacc
    43141 gctcataatc tgcactggca gttagttgta cgcaaatcaa gtacaataga agaataaaaa
    43201 cagataaaat gttgagagca taaagaggtt gtgagtctcc cgtttagctc tgagttacaa
    43261 ggaataatgt taaaaaacag cttttcatgt tttatgaata ttgccttgtg accgaggtgt
    43321 tggcaggaga atactgttta tttgaaaaaa gggctgcgac aagacttttg tcacagcctt
    43381 tattttcatg aataggagtt acttttggct acttttagag aagtagcttt taaggagcag
    43441 ataaagtcaa ggcttttatt tctataaatg aagtagtaaa atgaagaaca gattttatta
    43501 caggaaggat gccgataatt gtgatcattg ttgcaggaac gatcggtgca gggaaaagca
    43561 cactaactga aatgcttgcc caagatttag aaacaaaacc tttttatgag aacgtggaag
    43621 ataatgaagt attgccgcta ttttattcta atccagaaaa gtatactttt ttattacaga
    43681 ttttcttttt gaacaaacgc tttttggcaa tcaaagatgc tttcagccat gatgacaacg
    43741 tactagaccg ctccatctac gaagatagta tgctgtttca tttgaatgca gatttagggc
    43801 gtgtttctga agtagaagta aagcagtatg aaggtctttt agaaacgatg ctgaaggagt
    43861 tagaagaaat ttcgccacaa aagaaaccag atctactggt ttatattcgt gtatcctttg
    43921 aaactatgtt agcgagaatc aaaaaaagag gccgggaata tgaacagcta gaacaagatc
    43981 ctgaactcta ttcctactat aaagaactca atcgacgata cgaagagtgg tatgaacagt
    44041 ttgatatatg tcccaaaata gtgatcgatg gggacaaata tgatttcgta gccgatccgg
    44101 catgtggaga acaaatcgta caagaaatca agatgcgggc aaagaaaatg acagaagagg
    44161 cagatgccca gtcgatccgc tacactacaa ataacccgaa agcaaaggga atctttacaa
    44221 ctaaataata taaaaactaa gcaaattgct cactcgcaga tatttctctg tgagcagcat
    44281 cttgcttagt ttttttgatt cattgagatc aaatagtgaa ccgattcgta tgataaaatt
    44341 gccataaatg aaatgtctga gtgagggcca tgatcaaaaa taaaatggaa acgatcaaaa
    44401 tcgaatgggc gccaaacaga tgatgacaga aaacaaggac aatagctcct gcgataaagg
    44461 caagaacgac acttagatag tggaaaaatc gatcaaaatc tgctttttct ttagaaatac
    44521 aataatcata taagttcgtt gctacccctt ttaaatttcc agttgtaaat aaattagtgt
    44581 aggcacgccc gttgatttta tcaaaagcta cccactggat cgatgcagta aaagcaatca
    44641 aaatcgttac taatgcggga tgctcatgga cgggtgtcaa actaacaaag aaaaaaatca
    44701 ctgcttcata atatagaaca aacaagcgcc agaaatgttt ttcttttttt ctaaaataat
    44761 caattagata ctttgttaga agaatcccta agaaaaagaa aagggtagac aatacttttt
    44821 taccaacact tagccattct ccgtcaaatg cttggatgat cgatagaatg atattgccag
    44881 tttgagcaga ggcaaaagca ccatattgga tataagtata actgtccatg gctcctccga
    44941 taaatgtcag caaaagtcct attgtacgcc cctcgtgaaa ggaagtctgc atttttttca
    45001 tcacctttta tgaatatttt tgtcttcctt atcttagcat aaacgattga aaaaaaggaa
    45061 aaattttcag aaaactaaaa tcatatcgct tcccattttc atttttagaa aggtctgtta
    45121 gtataaagaa aaaatagaca acgaaacttt aaataaccaa cttgaaataa acaaattcaa
    45181 agaagaaaga tgggaaggaa atcaatcagt tgaatgaaaa agaaattctc cgattacaaa
    45241 aagaattgaa acgctgggag aacaagtata aaaagcttca acaagtcttt cggctacaag
    45301 aagaaatcat tgctacctat gaagcggctt atggcgaagc acccggactt attgaggaag
    45361 aagtacaagt aaaagaaagt gaaggaaaca gctctttctt taaaatgatg gagaaacgtt
    45421 cctataatcg cttcaatcaa gaacaaaaag cagctatcac atatgatatg aagaaacatc
    45481 ttcgaatcat agcaggagct gggagcggca aaacgcaaac aatctgtgca aaagctgttt
    45541 atctgatgac gcaaaaacaa gtagacgaag aacgcatact aatgatcact tttacaagga
    45601 acgctgcaaa tgaactaaaa aaacgagtag ataatttcag ccagagaaaa accgctgtcc
    45661 atatcggaac attccatagt atctttttta ggatatacaa tgaaatttgt cgaaaatttc
    45721 ctgaagtagc aatgcaagga atacaaggag acttttcaaa ggatactgca caaaaagtga
    45781 atgctgtttt gcaacagctg atacgtaaat ataatcttta tatatttgat caatatggag
    45841 aaaaaacgat tgcttctcgg ttagactatt ggcagaatat gaacctttca gtagaagaaa
    45901 tggttcagtt agttaaagaa aaatatgatt ccattgataa gaatgcacga cagccgatat
    45961 cagaacgact gtatggattg ctcacggaac tccaagaaca aaaaagaagc cagcaattgc
    46021 tagagttcaa tgatgtactc caaaatctga aaagcgcttt ggagaatgag gagatccagc
    46081 attatatcgg ccaaaaatat gattatctat tcattgatga atttcaagat actaatccac
    46141 ttcaatggga aatcgtgaaa cggatgacaa aggaaaacag gatcaagttg attgttgttg
    46201 gagatgatga tcagagtatc tatggattca gaggatcaga gccagcatac atcaagaact
    46261 ttgaaaaaga atatcctacc aaaactcttt tcttattaac taattatcgt tctcgggcag
    46321 ctattgtcca aggagcaaat agattgatca gctataataa aaatgatcgg ataccaaagg
    46381 cgatgattcc agcacaaaaa gaagcaggtg ttatggaagc ctatttgttt tctgatacta
    46441 aagcagaaag tcagtggcta atcaaacaaa ttcagacatt tattcaaaaa aatgggaaat
    46501 ataaggaatc aatcatatta taccgatcag cttcacaaac gcagcagctt gtccaatctc
    46561 tgctgaaaac gaatattcct tttgtactgg aagcagatag tccatatgaa ggtatctttg
    46621 gtatcaagtc tttccaacat ttctatcaaa aaattgttca ttggcaaaca gcactgaatc
    46681 tgcaaaagaa aaatcaggcc taccagcaat tgctccggca gctgatggca gactgctacc
    46741 tgaaaaaaag tgaatgcgat caatactttt ctcctaaata tcaaaatata gccgttgcag
    46801 attatatttt gtcgataagc cccaatttaa aatcgaaatc tgcagaaatc cgagagtttg
    46861 aggaagcgtt gcgtaaaaca gaccagcatc aagaaatcta ttcgcttgtt caaagctatc
    46921 ttcatctgcc acgtatagct aaggaaatcg accagagtga tcaagaatgg atacgagaag
    46981 aagtaaagca gcatgctact ttcagaagac tccaagcctt atcgcaagaa acccaagcga
    47041 cagctaaaga attaaaaacc cgcttgattg cttacagaca aggaaaactt gatgcactat
    47101 gtatccagag cattcacaaa agtaaaggtc ttagttaccg aaatgtcttt ttgattggtt
    47161 gtaacgaagg aagtttgcct tataacggag cgacagaaaa gaaagtaatc gactttaatg
    47221 aaataaaagc agaaccagta acgacgatag aagaagaacg aagactattt tatgttgcga
    47281 tgactagagc aagaaatcgt ctgtatctat gtgtacctca aatgaaaaat tcaagaaaat
    47341 tgaaagtatc gagatttatc aaagaaaccg ggagtcgtgt gaaaaaagga aagtgataga
    47401 agagagggtg tgacagaagt ggtcagtttc aagaaagaag aaggaatgta cgaaaattgc
    47461 ttctcaaatt tttgtgaaat ttcagcttat tttcgaagaa gctatttctg gaacacagtt
    47521 tattcggaaa agggaggtgt gacaagaatt ttgtcacacc tcccttattt attttgaaaa
    47581 tgagaatact attatcaaaa tagagaatat atagaaaaat tctcattatt caaacgtaaa
    47641 taatcagtta ttttgatttt ttttatattt tattagctaa taattggtat tttaaaagaa
    47701 attactgtag aattggatta taattaaaaa ggagtgagaa aatgataaaa gtatatactt
    47761 cgcctagctg tacttcctgt agaaaagcaa gagcatggtt gcaagcgaat caacttgaat
    47821 ttgaagagaa gaatattttt gccgaaccgt taacagaaag tgagatcaaa aagatcttgg
    47881 cagcgactga aggaggagtt caagatatta tttccactcg gtcgaaaatt tacgaaaagc
    47941 tgggcataga ttttaacgaa ttaactttaa agcaaatgat cgtcttattc aaagaatatc
    48001 cttcattatt gagacgacct attttgattg atgaaaaaag aatactaatc ggatttaatg
    48061 aagatgagat ccggtcattt gtccctcgtg aaattcgatg tgttgccaga aatctgatct
    48121 atttacaaaa caataacatc ttaaattcat agggagggag ccttcgtgga agtgaaagtc
    48181 tatggatcag cgcactgtgt aacaagtctg aaggcgaaac aatggttaga acaccatcaa
    48241 ttgccttatc aatttgttga cttagaagaa cgcgatctaa gtacagaaga agcagaagaa
    48301 ttatgcagtt ttgaagaagt gcaagcagaa cagctatttg cgacttggtc tgaggctttt
    48361 cacaacattg cgattgacct ttcctgtgta ggaaaaaaac aactgatttt tttatgcaca
    48421 caacatacca atctcctcag acgtcctttg attattatcg atgaagttct atttattgga
    48481 tacaatgagc agttgatgga acagcttatc ttaaataaat agactttaac tgttttaatc
    48541 aagtcactga gcatttcata cagttgtaac agtcgaacac ttagcatcaa gcgtgttatg
    48601 tgttcttttt ttgactttat ttttctacta tagagacatg ctcaatttat gtggtcaaaa
    48661 ttcaaatcta ggtggggata tagagttaaa aatatattga catgtgtaaa tttacatgat
    48721 atattcattt ctgttgtttt aagtagcaaa gcaataaaat agtattttaa aaaacatata
    48781 aaatagttgt tgacatgtta gaaatgacat gataagataa ctgagttgtt aaaaaagaac
    48841 cacttgtgaa gcttgattct atcgaaaaaa acttcaaaaa agttcttgac aaataacaaa
    48901 tgataagtta tgataaatga gttgctgtaa gatttcgaaa aacgaaatca aaaaaacttt
    48961 taaaaaagag ttgacaatta cttgtctctc tgatatgata taaaagttgc tacggcagcc
    49021 aaaaacgaat cggggaacac tcctgatgaa gtagaccttt gaaaactgaa caaagtaaga
    49081 caaaccaaat gtgtagggcg tcttgattca attcaagaca acaaaca
//
LOCUS       DAZKCW010000019        48825 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000019 DAZKCW010000000
VERSION     DAZKCW010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48825
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.019"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..350
                     /locus_tag="ACG84Z_001145"
     CDS             <1..350
                     /locus_tag="ACG84Z_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9161999.1"
                     /translation="EAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFE
                     DAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDE
                     WIYSSRKYINFDK"
     gene            407..799
                     /locus_tag="ACG84Z_001146"
     CDS             407..799
                     /locus_tag="ACG84Z_001146"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9162000.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            800..1600
                     /gene="aac(6')-Ie"
                     /locus_tag="ACG84Z_001147"
                     /pseudo
     CDS             800..1600
                     /gene="aac(6')-Ie"
                     /locus_tag="ACG84Z_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
     gene            1637..2596
                     /locus_tag="ACG84Z_001148"
     CDS             1637..2596
                     /locus_tag="ACG84Z_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFP9162001.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            2766..3446
                     /locus_tag="ACG84Z_001149"
     CDS             2766..3446
                     /locus_tag="ACG84Z_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFP9162002.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            3536..4570
                     /locus_tag="ACG84Z_001150"
     CDS             3536..4570
                     /locus_tag="ACG84Z_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFP9162003.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            4584..4919
                     /locus_tag="ACG84Z_001151"
     CDS             4584..4919
                     /locus_tag="ACG84Z_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162004.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            4903..7383
                     /locus_tag="ACG84Z_001152"
     CDS             4903..7383
                     /locus_tag="ACG84Z_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162005.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            7439..8998
                     /locus_tag="ACG84Z_001153"
     CDS             7439..8998
                     /locus_tag="ACG84Z_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162006.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            8995..10359
                     /locus_tag="ACG84Z_001154"
     CDS             8995..10359
                     /locus_tag="ACG84Z_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFP9162007.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            10530..11600
                     /locus_tag="ACG84Z_001155"
     CDS             10530..11600
                     /locus_tag="ACG84Z_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162008.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            11615..12283
                     /locus_tag="ACG84Z_001156"
     CDS             11615..12283
                     /locus_tag="ACG84Z_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162009.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            12303..12881
                     /locus_tag="ACG84Z_001157"
     CDS             12303..12881
                     /locus_tag="ACG84Z_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9162010.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            13282..14193
                     /locus_tag="ACG84Z_001158"
     CDS             13282..14193
                     /locus_tag="ACG84Z_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFP9162011.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(14571..15488)
                     /gene="rnhC"
                     /locus_tag="ACG84Z_001159"
     CDS             complement(14571..15488)
                     /gene="rnhC"
                     /locus_tag="ACG84Z_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFP9162012.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            15690..16127
                     /gene="zapA"
                     /locus_tag="ACG84Z_001160"
     CDS             15690..16127
                     /gene="zapA"
                     /locus_tag="ACG84Z_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFP9162013.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            16185..16733
                     /locus_tag="ACG84Z_001161"
     CDS             16185..16733
                     /locus_tag="ACG84Z_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFP9162014.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            16848..19208
                     /locus_tag="ACG84Z_001162"
     CDS             16848..19208
                     /locus_tag="ACG84Z_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFP9162015.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            19295..19609
                     /gene="trxA"
                     /locus_tag="ACG84Z_001163"
     CDS             19295..19609
                     /gene="trxA"
                     /locus_tag="ACG84Z_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFP9162016.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            19791..21569
                     /gene="uvrC"
                     /locus_tag="ACG84Z_001164"
     CDS             19791..21569
                     /gene="uvrC"
                     /locus_tag="ACG84Z_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFP9162017.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            21714..22613
                     /locus_tag="ACG84Z_001165"
     CDS             21714..22613
                     /locus_tag="ACG84Z_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162018.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            22606..23868
                     /locus_tag="ACG84Z_001166"
     CDS             22606..23868
                     /locus_tag="ACG84Z_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162019.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            24029..25927
                     /locus_tag="ACG84Z_001167"
     CDS             24029..25927
                     /locus_tag="ACG84Z_001167"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFP9162020.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(26257..26976)
                     /locus_tag="ACG84Z_001168"
     CDS             complement(26257..26976)
                     /locus_tag="ACG84Z_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFP9162021.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    27166..27213
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            27313..27645
                     /locus_tag="ACG84Z_001169"
     CDS             27313..27645
                     /locus_tag="ACG84Z_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162022.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            27632..29635
                     /locus_tag="ACG84Z_001170"
     CDS             27632..29635
                     /locus_tag="ACG84Z_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFP9162023.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            29654..30124
                     /locus_tag="ACG84Z_001171"
     CDS             29654..30124
                     /locus_tag="ACG84Z_001171"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFP9162024.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            30145..30729
                     /locus_tag="ACG84Z_001172"
     CDS             30145..30729
                     /locus_tag="ACG84Z_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFP9162025.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            30744..31730
                     /locus_tag="ACG84Z_001173"
     CDS             30744..31730
                     /locus_tag="ACG84Z_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFP9162026.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            31720..32031
                     /locus_tag="ACG84Z_001174"
     CDS             31720..32031
                     /locus_tag="ACG84Z_001174"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFP9162027.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            32053..33834
                     /locus_tag="ACG84Z_001175"
     CDS             32053..33834
                     /locus_tag="ACG84Z_001175"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFP9162028.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            33827..35203
                     /locus_tag="ACG84Z_001176"
     CDS             33827..35203
                     /locus_tag="ACG84Z_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFP9162029.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            35210..35845
                     /locus_tag="ACG84Z_001177"
     CDS             35210..35845
                     /locus_tag="ACG84Z_001177"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFP9162030.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            35875..37230
                     /locus_tag="ACG84Z_001178"
     CDS             35875..37230
                     /locus_tag="ACG84Z_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFP9162031.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(37422..38816)
                     /locus_tag="ACG84Z_001179"
     CDS             complement(37422..38816)
                     /locus_tag="ACG84Z_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFP9162032.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            38908..39879
                     /locus_tag="ACG84Z_001180"
     CDS             38908..39879
                     /locus_tag="ACG84Z_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFP9162033.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            39876..40658
                     /locus_tag="ACG84Z_001181"
     CDS             39876..40658
                     /locus_tag="ACG84Z_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFP9162034.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(40827..41198)
                     /locus_tag="ACG84Z_001182"
     CDS             complement(40827..41198)
                     /locus_tag="ACG84Z_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9162035.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            41332..41775
                     /locus_tag="ACG84Z_001183"
     CDS             41332..41775
                     /locus_tag="ACG84Z_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFP9162036.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(41818..42627)
                     /gene="yidA"
                     /locus_tag="ACG84Z_001184"
     CDS             complement(41818..42627)
                     /gene="yidA"
                     /locus_tag="ACG84Z_001184"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFP9162037.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(42646..44013)
                     /locus_tag="ACG84Z_001185"
     CDS             complement(42646..44013)
                     /locus_tag="ACG84Z_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFP9162038.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(43997..44827)
                     /locus_tag="ACG84Z_001186"
     CDS             complement(43997..44827)
                     /locus_tag="ACG84Z_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFP9162039.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            44990..45427
                     /locus_tag="ACG84Z_001187"
     CDS             44990..45427
                     /locus_tag="ACG84Z_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFP9162040.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            45503..46123
                     /gene="rpoE"
                     /locus_tag="ACG84Z_001188"
     CDS             45503..46123
                     /gene="rpoE"
                     /locus_tag="ACG84Z_001188"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFP9162041.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            46312..46818
                     /locus_tag="ACG84Z_001189"
     CDS             46312..46818
                     /locus_tag="ACG84Z_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFP9162042.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            46835..47734
                     /locus_tag="ACG84Z_001190"
     CDS             46835..47734
                     /locus_tag="ACG84Z_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFP9162043.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            47821..48705
                     /locus_tag="ACG84Z_001191"
     CDS             47821..48705
                     /locus_tag="ACG84Z_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFP9162044.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
BASE COUNT        16236 a         8327 c        10237 g        14025 t
ORIGIN      
        1 gagaagctgt taaaggaatt tttaagttca cagatattaa cttagcgcgt gaggctaaaa
       61 atcgattgat tcatgattat atcgatcaac caaaatattc aaaagcttgc gcatcattgg
      121 atgatggatt cgaagacgcc tttcaatata ccgtacaagg aaattcccac aatcgactaa
      181 agagtaccaa tctaattgaa cgactgaatc aagaagtacg cagaagagaa aagattattc
      241 gcatcttccc caatcaaaca tcagccaatc gcttaattgg agccgttctt atggacctac
      301 atgatgaatg gatttattct tcaagaaaat acatcaattt tgataagtag aaatggtaaa
      361 aacattgtat agcattttac acaggagtct ggacttgact gagtttatgg aagaagtttt
      421 aattgatgat aatatggttt ttgatattga taatttaaaa ggatttctta atgataccag
      481 ttcatttggg tttatagcta aagaaaataa taaaattata ggatttgcat attgctatac
      541 acttttaaga cctgatggaa aaacaatgtt ttatttacac tcaataggaa tgttacctaa
      601 ctatcaagac aaaggttatg gttcaaaatt attatctttt attaaggaat attctaaaga
      661 gattggttgt tctgaaatgt ttttaataac tgataaaggt aatcctagag cttgccatgt
      721 atatgaaaaa ttaggtggta aaaatgatta taaagatgaa atagtatatg tatatgatta
      781 tgaaaaaggt gataaataaa tgaatatagt tgaaaatgaa atatgtataa gaactttaat
      841 agatgatgat tttcctttga tgttaaaatg gttaactgat gaaagagtat tagaatttta
      901 tggtggtaga gataaaaaat atacattaga atcattaaaa aaacattata cagagccttg
      961 ggaagatgaa gtttttagag taattattga atataacaat gttcctattg gatatggaca
     1021 aatatataaa atgtatgatg agttatatac tgattatcat tatccaaaaa ctgatgagat
     1081 agtctatggt atggatcaat ttataggaga gccaaattat tggagtaaag gaattggtac
     1141 aagatatatt aaattgattt ttgaattttt gaaaaaagaa agaaatgcta atgcagttat
     1201 tttagaccct cataaaaata atccaagagc aataagggca taccaaaaat ctggttttag
     1261 aattattgaa gatttgccag aacatgaatt acacgagggc aaaaaagaag attgttattt
     1321 aatggaatat agatatgatg ataatgccac aaatgttaag gcaatgaaat atttaattga
     1381 gcattacttt gataatttca aagtagatag tattgaaata atcggtagtg gttatgatag
     1441 tgtggcatat ttagttaata atgaatacat ttttaaaaca aaatttagta ctaataagaa
     1501 aaaaggttat gcaaaagaaa aagcaatata taatttttta aacgccgatt gtaaaattaa
     1561 gctagacaac taaaaaaagt catttgtgct acactcaaaa tagttccgac gaaagaatta
     1621 taaggagtga gtacaaatga cctataacca tcttacacca actgaactcg taatgataga
     1681 agcttatttc aatcaatcac aacctgtttc aaaagtagcc aatctgttac aacgttctcg
     1741 acaaactatt tataaggtct atcgttttct taaatctggt ggaagcgcaa tgagctacta
     1801 taaacaatat aagaaaaaca aacgtaactg cggaagacat ccgattgttt tacctgatga
     1861 gcaacaggaa tacattcaaa aaaaggttgt tcaagggtgg gctcctgatg tccttattgg
     1921 tcgagcagag tttcctattg cttgttcggt acgcacactg tatcgaatgt ttaaagataa
     1981 aacctttgac actcacgatt taccaatgaa gggaaaaaga aaaccaaacg gtcataaaga
     2041 aaaaagagga aaacaagggt ttcgccggtc aatccgagac agaaagacag actataccca
     2101 gtttgatcat gaatttggtc acctggaagg tgacactatc gtgggtggaa aacataaaag
     2161 cgcggtcatc acattagttg aacggctatc taaagtcatc attaccttga aacccgaagg
     2221 cagacaggct aaagacattg aaaataggct gaatcaatgg tttcgttgtg tcccaaaaaa
     2281 cttatttaaa tccatcacat ttgattgtgg aaaagaattc tcaaattgga aaaagattag
     2341 taataccaac gatatttcaa tttattttgc ggatccagga acaccttctc aacgaggatt
     2401 gaatgaacat tcaaatggct tattacgtaa agatggtttg tataaagcta tggattttaa
     2461 tggtgtatct gaaaccttta tccaatcggt ggcatcgaaa cgaaatcata ttcctagaaa
     2521 atcattacac tatcggacac caatggaagt atttttgagt tacgtcacaa aagatgattt
     2581 gtctaactta atttgacaaa cgaaacttaa taaaaaagga agaatattca tgtaaacgat
     2641 tttattgttt ttttctcttt tatacaaaaa gggtcataat ttcaagtaag cggatgaatt
     2701 catgaggatt ttttgcatac tgtctctact atacttaggt cactaagaaa aaggagtgat
     2761 ttattatgaa aaagaacatg attgggacat tattactttc aacacttctt ctaggcggct
     2821 tggcaacacc agcttttgct gagggtcaag cgacttcaaa aggagatatt acctttactg
     2881 aaccaacaaa taccgtggag cctcttaacc ctactgatcc ttcaaaacca gtagagccag
     2941 cagatccgga aaatccagca actggccaga caggtccttt aacactggat gtagttcccg
     3001 aattgccatt tggtacacac gagattgaaa gcggaacaaa aacgtatcaa gtagacgctt
     3061 caaaaaacga tacaccttat ctccaagtat cagatcgtcg aggtgtaggt gcagatggcc
     3121 aagcacaagg gtggaacgtg acagtttcgg tttcagattt tgtaaacggt tcacaagttt
     3181 tgcaaggcgc tgaattagat tttggaacat ccactgttaa aagtacgtca gataacgaat
     3241 ccactggacc aactagtcaa actgtaactg ggttgagtaa agcaagtgca gcgacaccaa
     3301 tatttacagc agcaaaagat caaggtctgg gaacatggct ttctgtttat gatccagcaa
     3361 atatcacact gaaagtgccg aaagcagcag ctggaacatt cacggctgat ttgacttgga
     3421 acctcgtggc tggcccagta gcatagagta tgaaataaat tcaacaaact gcggtgaaaa
     3481 tactataggt gaaggatttt ttaccgcagt tgttgttgaa aggatgtggt ggacaatgaa
     3541 tcaaagtaaa cgactgtttg tttcgttttt ttctatttta agtctatttt tcatttttcc
     3601 gtcaatcagc caagcaaagg attcagcagg agactttgga atcaaaccgg tatttccaga
     3661 gaaccaaata gataaagcaa tcggttattt tgatttatta gtggcaccgg aacaaaatca
     3721 gacactagaa gtaattatca gcaattcttc agatgaagaa cgaacatttg aggtctctgt
     3781 caatccggcg gtaacgagtg atggtggaac gatcgattat agtcaaaaaa acccaacgtt
     3841 agatgagaca ttgccgtttg atgtccgtga cgttttgctc attgcgaaaa aggaaatcaa
     3901 tgtatcagca catgcagaaa caactgtacc tatagaagtg aaaatcccag caaaaagctt
     3961 taagggacgt gtattagcgg gtattcatgt ttcacctaaa gaagaagctg aaacagaaaa
     4021 tgctacagaa ggagcacaaa tcaaaaatcg tattgcttat aatctcgcag tcgttttaca
     4081 agaaagtcaa gagacgatag aaccggatct gaaactttta tcaggagatt tggacgaggt
     4141 caacgcaaag ccaactgttc agcttcgttt ccaaaatcct cagcctagga ttatcagcaa
     4201 tttgatattt acgagcaaga tcttttatga aaatcagctt tatattgaaa atacgtctaa
     4261 tgcattttta gttgcaccaa attcgaattt tcacttgaat cttgatttag ctggtgataa
     4321 agcaaaagcc ggcgattacc gcgcagaaat catagcaaaa tcaggcgaca gtaatgaatg
     4381 gcgatttaca caaaacttta cgatcaaaaa agaaaaagca caaaaagtaa atgaaaattc
     4441 cgtttttgca gtacaagaac aatctttccc atggctttat gcaggattgg ttgctgcagt
     4501 tctagtgtta tggttgattt tgctgttttt gtgggtccac aagaaaaaga aaaaaggaga
     4561 aacaacatga tgaggtgatt tcgttgaaaa catcgatctt attgggaggg attattgcaa
     4621 gtttgctgtt cttcagctgg caagagccag tccaagcaga taccaaaagt tcaggtacga
     4681 ttacatttta tgatctaagt ccaattccgc atccaagtgg ttcagtcaat ggcgcatcaa
     4741 aacagcagac acagctaccg atttataaag aatctaatca acatggcgta ttcccggaga
     4801 cgaatgaaca aaagatccgt tttctttatt tgatcattgg tatagaatta tggcttcttg
     4861 cgtggttgtt gttatggaga agaaaggaaa aggaggatga acatgttgct acaaaataaa
     4921 ttttcatttt ttcgctcctt cttttttact tcgctttttg ttttaagtat atttatcttt
     4981 tcaccttcgg cagaagctgt tggagcaacg cctcctgcca tttcttatga tccatacacg
     5041 tatgaaaata tcgtacctcc aaatggtgga cgtagtgcag tcaatggcgg gaagcttgtc
     5101 caactaactg gggctaacca attgcctaaa ttgactgcta cttatttgaa cgatggttca
     5161 aatgatcctt ggaaaggtgg cacggtccgt tttcattggg aaagccatgt gaaactaaca
     5221 aatgtacttg atttggtgaa tatcactgca caaggatttg catttgtggc gatcatcaat
     5281 ttgccggaac atgtatcaag cagtgatgta ttaaaagcaa ttgactggaa caacgcctac
     5341 ttgtatattg ccggtgcccc catcaaggtt actagcggaa gtttattatc agcaggaagc
     5401 cataccttgc gttttgggat ggggtcgtgg gatacaaata ctctattgac agatattatt
     5461 gctattatta cgcgaggcga attcaacgtg gacgatatcc cgcttcaatt tgatgttaca
     5521 gctaatgtcg cgaagatgac agaaaacgga gataaatatg atacgagtcc aaacaaaatt
     5581 ttgaccaagg gtaaattaca accttctatg tctaaaaagg ccgttttttc tgttgatttt
     5641 tatgattcga ataatattat ccaagatcgt atgttcaatt cgattttagc tccagctgca
     5701 ggtagatttt atcctaaatt aactggcgga aacttgaatc caggagcata tgcattttct
     5761 gcaagtgcag agataaatac gtggaatagt tacatctcac caagtgattc aacaggaaaa
     5821 tataatacat ttgctgatac cacagaatac gtggatggaa ataaccagaa ccttccaggc
     5881 tctaccaata gtcggacatt gacgatgggg ctgactgaag gacgttttga tcagttgcca
     5941 tttagtcgct ttgatcgcgt agtcaactat tttacaggaa aaaacgttac acaaggagca
     6001 atactgactc atactccagc aagcacaagt ggattgaatc agacagccaa tatcgtgtac
     6061 agtgggaaag atgcgcaagg cggattgctt tctcctgttg ctttaaaggt attggagcag
     6121 tacaagctag acggaacggt tttaccaaca aacttaacag ccgatagtca gtggggaaag
     6181 ctcctttctt ctgcatcgta ccaagtcacg gccaattggt cagcaactga actaaaaaag
     6241 ggttcgatcc attacaggct ttattcgaaa ggaacccaaa aattagcgac aggatggaca
     6301 gatcaacttt tccaaacgat ccaatcaaat aacgggggtg taaatacagc tacttctaca
     6361 ctacctgcat tggcttcagg gcaatattat tttgattatc gcttggtgga cgatgtactt
     6421 actaacatgt atccgtcttt tgcgtacaaa tggcagtctg aacaagctgg aatcaccact
     6481 cttcctcaaa taacagtggc taattttcca tctgtgagtg cagatagtca gctaaaaaac
     6541 cttagcagac aacctgagac aggagatccc ctgtctgctc tatcaggaga tacgattcaa
     6601 gaaaatgtga cattcacgtt aacaaaatct ggggatgcga taaccgacaa aaaaatcacg
     6661 atctcacttc ctgaaaatac tacttatatc aatggttcct taaaattaaa tggtacaact
     6721 atcgcagata ccggcattca acaaggagtt tctgtcccag cagatctatt gagcaaaata
     6781 ggagatacca ttcatcttac ttacaactat caattaaata ctgtagatac ttctttacaa
     6841 tccgtcagca tactgacaaa ggcagctgta ctttccagca atattacatt agcagatggt
     6901 gctaagcttc ctaacccagt tgtccaaaca tctgctaaaa caattcttgt ccccaaacaa
     6961 gaattaacat tagttaatgt accagatgat tttacatttg gtaacgatct ccccaaaccg
     7021 ttgaagacaa gttattatga atcaaaaggc gatttttctt ttgatgtgcg ggatactcgg
     7081 cttccaagca cgtctccttg gcaactgaca ggtacattga cttctttatt taagaatgat
     7141 caaggtcaag aattaagcgg aacaaaatta tacttcaatc attctggatc aaagcaattg
     7201 attcagcaag gtcaaaacac gttgatttat gagagtgatg gaacagctaa aggagaggtt
     7261 ctcgttgact ttcccgatac cgatggttta ctcttagagg taaatagcag tacgaatgct
     7321 caacctggcg caacgtatca aggcatggtc acatgggaac tgacagctgg gccaaccagc
     7381 taagtgatta gaatttgtat ggatctgtga taactgtcac agatcctctt tttcaaggat
     7441 gagaaggaaa cttctgctgt taaaatcaga aatgcttgaa ggagtggact tggaactttt
     7501 cagtttgctt gaaaaaaatg aacaacggca aatcaaactt ttccaacttt tattagagga
     7561 aaaaggagag gtttccgtta ataacgtact tacccgctta tcagttgatc gggctacctt
     7621 gaaagaagat ctgttttatt tacaagctaa cttggaaaat atcaaacaat tggaaattgt
     7681 tatccaagaa gggaatattt tattaatcag acatggaaat atagcagcag tcgatgttta
     7741 ttatcattgt tacttgcgct attctacaaa atatcagata cttctttatc tgttggaaaa
     7801 tggctcattt gatcggcaga aacttgtcat ggaacttaat atcagttcgg ctactttgtc
     7861 tcgcagagtg aaggaattaa atgattcttt aaatgagttt catctgaaaa taaaaagcgg
     7921 gcggctgacc ggtccagaaa gtcaaattcg ttatttttat ttccaattat tttggtttgg
     7981 acgtccctat cttgaaaaca aaaaagaata cagtgattta tcaggaaaca cttttttaga
     8041 tctgctgcaa aaagagttta gttttgctat tacagaagaa ggacgattga aatttgaaat
     8101 atggctttcc attatgaaga agcgaatgcg ctgtacgaaa aaatccaaac cagattatag
     8161 caatcttcct gttggattgt ttcaaacgac acaattttta ttggacctcc atacattttt
     8221 gacccgttac ttctttcaat atgcctttcc ttggaatcaa aatgaaacgt tggtttttta
     8281 tcttttcatg atcagtaact ttacattaga tacacataac tcgcatgtcc aggagttttt
     8341 gataagcgaa aaatacaaag acgacgtagt agctcaattg aatcgaacgt ttaaacaatc
     8401 gatagaagaa tatttctctt tttatgtttt tccagaagag atttcgcaaa agattgcgtt
     8461 gacagtgatg caaaatcacg ctcattttgc ctattttaga ggatggatga atatttttgg
     8521 ccaagaagga ttaaaacagc ggttaactga agtagaagat aaacaattcc tggttttatg
     8581 tgaaagattg gtcagacaaa catttgctat tgttgatttt actgaagtag acgaggaaaa
     8641 tgcccgcttt gaattatttg ctcgctatgc atctatttta cggacgctga tcaagcagtt
     8701 agaattacgt ctgcaaattg cttatgatct tccttatgaa aggctaatgg cggatatcgt
     8761 gaaagaaatc atccaggaac aattgctgaa tacgatcaaa tatgatttag tcgaatacga
     8821 gaaagaaaag cagtatgata tcattttgac tagccaattg aaagagtacc cgtcacagaa
     8881 gtccgctaaa gtttttgtat tcactagcaa cgaatataat tatgatttcc cctatttgaa
     8941 ccaattttta aaagaatgtt atttagaaaa attgaattta aggatgaata aaacatgaaa
     9001 atcgtgatca ttggtgcttc ccatgaaggc atcacagctg ccctaaatct aagaaaactt
     9061 caaccgaaag cagaagtttt actgatcgat gaagatcata aagatggact aggctatgtt
     9121 tcaaatggaa tcaaccttta tttaaaagga aagatacgta gtttagctga agttgcccat
     9181 aacatgcgga ctcttcaaga aagtggggca aaactgatca ccgaatggag agtaactgaa
     9241 cttgatccag acaaacatca gctcatcctc gcatccaaag aaggaaaaaa cgagaccata
     9301 acctatgata aattaatcgt agcgacaggt tcctctcctg tcaccttgta taaacaaatt
     9361 gaagctgaaa atgtctacac ctataaaaat ctagtgcaat ctaagcaagt acttgccgct
     9421 ttaaaagaag caaaagaagt agtgatcttc ggtgctggtt acattggatt ggaattagca
     9481 gatgctttga gaaataaagg atacattatt catctagttg attatatgcc gaatgtttta
     9541 tcaagatatt tcgataagga tatgatcaac agttttcaaa atcagctgca aactaagcaa
     9601 ataaattttt atccaaatga attcttgatc gattggaaaa aatcagaaga gaaagtagta
     9661 tccgtacaac ttctgtctca aacaataaag gcagatatgg tcattttttc tgcccaaact
     9721 cgtcctaata cgacattgtt aaaagaaaaa gtggctttgt atgaggatga gactgtgata
     9781 gtcaatgaat atctgcagac aagtgatccg gacatctatg cgattggaga tatcgtccca
     9841 gtcagttttg acaaaaataa acggcatctc tttttacctt tagttactcg agctgtacat
     9901 atggcaagag cagtagcgct aactttgagt ggtcagccaa ccgcttacga cctcagacaa
     9961 aagataacag cagcagtcat tatagactac tttttaggaa ctgtagggct gacagaagat
    10021 gaagcgccat tcttggaaca aaataccggt tcgtgttcag gagaatttga tctatttcca
    10081 caatacgacg aagaaaacaa aacagtaaat gcaaagctga tctaccatcc ggatacatta
    10141 gaaataattg gcggacagct gataagccaa gaattcttat tatcagattt gaacctgctt
    10201 gcggatatcg tgaaacacaa aactacgatt ccacagctag cagttgagga ttttggattt
    10261 ctgtctgaat acacctctcg ttttcactac ctcaatgagt tagcttttaa agtactagct
    10321 aagagagcaa atagcaatag agtagataaa agactgtgag aaatatcacg gtcttttatt
    10381 gtgtggggat ataataaata ttaatcaatc gagaataaaa aattcatata atgaaatagc
    10441 ggaagaattt tttgagcata atattcgcca aaaatttatc aagtgataaa attgttgtat
    10501 aaaatgatta tttcaggagg aggagttaaa tgtttttagc attaaatgaa attatgcatt
    10561 caaagttacg ttatgcgtta gttgcagggg tgatgttttt gatcgcctac ctggtatttt
    10621 ttttgactgg gttagcttat ggcttagctc aagataatcg aacagcagtc gacaagtggg
    10681 aggcagattc gattgtgctt tcgaaagatg caaattcaaa tctagggatg tccatgatta
    10741 ctaagaagat agcagaagaa gtcgaaggtg ggaaagtggc gtatcttgcc caaacacctg
    10801 gagtcgtgac tagtaaagac agtacagaag aaggaaaaat caatgttagc ttcttcggta
    10861 tcgataaaaa tcaattcatc atgcccaatc ttgttgaagg aaaagctttt gataacgatg
    10921 atgaggcagt aggcgatatt agtttgaaag aagaatatgg tctagccata ggagatacag
    10981 ttaagttatc tggtagtgac aagacgttta aactaactgg ctttacggat catgccaaat
    11041 tcaatgtctc accagttctc tatacaacca tcaatgctta ccaagaaatc cgcttcgaaa
    11101 aagaagatac aagtgaaaat gcacggatta acgcaatagt tgtcagaggt aaaatcagta
    11161 atttacctga agatttagaa cagatcaaaa tttctaaatt catcaatgaa ttacctggat
    11221 ataatgcgca agtattgact tttggattta tgatcggatt tttgatcgtt attgcggcta
    11281 ttgtgatcgg gattttcatt tatgtactga cgatgcaaaa gattaatatc tttggtgtaa
    11341 tgaaagcaca agggatcaca ggaggattta ttgcgcgttc tgtagtggca caaacattca
    11401 ttttatcatt tgttggtatt cttcttggtc tattaggaac agtgggaaca tcccttgttc
    11461 tacctgatgc ggttccattc caaagcaatt ggctgttttt tggcgtcatt agcttgttga
    11521 tgttagtagt agctgtgtta ggcgcactat tttctgttcg gacaatcgta aaaatcgatc
    11581 cgttgaaggc aattggataa gaaggaggaa gaacatgaaa gcaatagaat ttaaagaagt
    11641 agaaaaaagt ttccaagatg gcgaccaagt agttaaagca ttgaaagaaa caaccatgag
    11701 tatcgataaa ggggaatttg ttgcaatcat cggtccttct ggttcaggta aaagtacttt
    11761 tttgactttg gcaggcggat tgcagacgcc tagcagtggc tctgtattta tcaatgatca
    11821 agaattcagt aatcaaaaag aaagcgaacg cgttaaacta cgttttaaag aaattggctt
    11881 tattttgcaa gcttccaatc tggttccttt tctgacagta aaaaagcagt tattattagt
    11941 agataagatt aaacatgaac atcgtcaaaa agaagcaaac gaattatttg agcagcttgg
    12001 cgtggataag ttgatcaaca agtatccaga agaactatct ggtggagaac ggcaaagggt
    12061 cgcaatcgct cgtgcattgt acaatgatcc gtccattatt ctagcagatg aaccaactgc
    12121 tagtttggat tcagaaaagg cacgagaagt agtcgatatc ttggcaaaag aatcaaaaga
    12181 caaaaataaa gcaacgatca tggttactca cgatacacgg ctgattgaca aatgcgatag
    12241 aatatttatg atggaagatg gtgtattgaa agaaaaagaa taaccaaaaa gcaggtggaa
    12301 aaatggtcca tcgatacaac aaagatacac agcaaaaaat tttgaaagaa gcgactgact
    12361 tgtttatgtc caagggatat ctcggcactt caacaagaga aatcgcacaa aaagttggga
    12421 tcacccagcc caatctctat cattatttcg gtgataaaga aaaactatat acggcagttt
    12481 tagaaaacca cttaaaagat gttggaaaag ctttgagaga aatcgttcaa acaagcgaaa
    12541 cgggatttca agtaaccttg acaaaaatgg cgcagttttt gattgagaca catctggtcg
    12601 atttgtttct gatgcttcac gatcttgaaa gcaatctttc aaaggaaaca agagatcatc
    12661 ttttctttct atggaagaaa aattatcgtg aaccttttga agaaatcttt tcagcaaacc
    12721 aatctgtgct aagaaatggg atttcaaaag aaatcgcagc aaggcatttt ttcttagtgt
    12781 tagcacctta catcactcgg tcgaaaagac ctgtggaaga accgctaaat gtggcgcaat
    12841 tgatcgattt atatttgaat ggtgtattag gagaagcgta aagctgttat atagggagaa
    12901 aatagttagg tgaagaagca agatatgacg aagatcgtta tatcttgctt ctttatatag
    12961 gtagtttttc ataaatacaa atttgttatt ctctcatgat tatcagggta tatttttatt
    13021 tattatgtcg gtgttccagg aagtgtttta atttaataac gaagaaatta attgtttgta
    13081 gaatgaagga aactatttat tgggtagatg aatcaccacg aatagtcaaa aggagatttc
    13141 aggatatgcc aaaaatgaaa aaaatcattt tagcagtaat gttattttct acggttatat
    13201 cttttacagc cccttttttg cttacttaag ctgattttaa gttttggccc ttagtctgga
    13261 tctacgaggt gagagtcaag aatgaaaaaa ataattggag cttttgtatt tgcaatcatt
    13321 atcattatta tctgttttca aatagatgtt tttggtcaaa aaaagatagt tggacaaacg
    13381 gtcagcagta cgaacagtac ggttacaaag acaaaggaat catttgatga tacagaacaa
    13441 gagacattaa tcaaaatcgg aaaaaatgac cgtacactat atacagatga ctcgctaact
    13501 accccacttg caactataaa cggcggagag ctggcggagt ttctttctga aacaaaaaat
    13561 gcttatcaga tcaagacaaa tgatggctat actggatatt tagccctcga agatggaacc
    13621 aaagtcacaa agaatataca aacaaaaccg gaagagctat ctgatgcagt gattgtatta
    13681 gatcctgggc atggcggaaa tgatactggg gcattaagca atgatgaaca aacagaagaa
    13741 aaagatataa cattaagtac agccataaaa gtaaaaaagg cgctagagga tgctggagca
    13801 acggtttatt tgacccatac tacagatgaa ttagtacagc ttggagatat atgcgactac
    13861 agtgaagaaa aaaaggcaga tgtctttatc agtttacacg cagactctac ggaatatgcg
    13921 aatgaagcaa ctggaatcac gacatattat tactatggac aagaggaaac attagcacag
    13981 acaattgctg actccttcac tgatctgcct ctggattcaa gaggaatctc cactgggaac
    14041 tatcaagttc ttcgagaaaa tcttcaacct tctattttaa tcgagatggg ttatatgaat
    14101 aatgatagtg atttaaagga attagtaaca gacagttatc agcagcagat tgctgcaagt
    14161 ttgacacaag cattgaccac ttattttcag taataaataa gcccagccaa acaaaaatag
    14221 ctcctcatat ttttcgtttg gccgggctta ttatcgcaga tgcaagcttt taaacaccgt
    14281 ttaaggaaga ggtcgtgagc ctgccgttca actctgagtc acaaggagca atttcaaaaa
    14341 acagcttctc atgtttgatg actattgtga cttgtgaccg aggagttggc atgagaacac
    14401 cgtttaagaa aaaggttgtg aaatcaacgt tttgttctga gtattagaga aacaaacgga
    14461 aaaatagttc ctcatatttt gccgtttgtt gagctaatac cgaggatcag atgattgaac
    14521 accgtttatt cggaacaagg gactgtgaca tgacttttgt cacagttcca ttattttttt
    14581 agtagcttca aagctttttc tgtattggca aaatgaagtt tggcatattt ttcaagcata
    14641 ggcatgccgc ctttctccaa tagttttgcc gctacttggt cagatttcgt tccagctcct
    14701 gacggaaggg tgattccagc ttcagctgat gctttgtcta actcttccaa aaagctggca
    14761 cgactgatga tagaagcagc agcaacagct aaatgatatt gttctccttt agtaacgaag
    14821 tacagttttt cttgtaattg atttttttct aaacgcgcat attttttaaa atttgcttcc
    14881 ggcgtaaact gatcgatcaa aatcgcttct ggtttttctg gctcgatttt ttttagcagc
    14941 aaatggatcg cttgattgtg caaagcgact ttcatccgaa cggcattgta ttttggttgg
    15001 atctcattgt atttttctgg agataagaca agcagtttat aggggatggt tttttttaag
    15061 atgtcagcaa gctggatgat ttggctatct tttaactctt ttgaatctct aacaccaagt
    15121 ttacgtaatt ctgcaagctg atcacgtttc acataagcag cacatactgt tagcggaccg
    15181 aaatagctgc catttccgac ctcatcacta cctaaaacgg ataattgact gatatttttt
    15241 ggcaaagaag aggctgtttt tgctggcttg gcttgtttat cctgtgcctc cccccattta
    15301 tcagcttcta ttgctgcatt cgtaccttga aacatcactt ttccggatgt ataagcggta
    15361 atggtcgtcc cgtctttttt tgcagcaaag ctagtataag gaatctgttt atttaacaaa
    15421 taagagcgat agtatgcttt catttgacta agttggtcgt ttgttgcttt gataatgacg
    15481 ttgctcataa aattctcctc gtttttatac ataaaactat accgcaactc acgacttttc
    15541 gttttctaag agattgcgag acatagcatt tttttaaagt ttatcatata atagttaagt
    15601 atgtgaaaaa tatttgtgga gaacggtgaa agaaccaact tcatggtaca ctaaataaaa
    15661 ctttcatcaa ataggaggaa atgattcgta tggcgcacga aaaaacacgc tacaaagcgg
    15721 tgattgccaa ccaaacatat actattatcg gacgggaaac caagcatcat atggatatcg
    15781 taacgaagct gatcaatgaa cagttagcag aattgaaaca attatcacca caaatggata
    15841 atgaacaagc agcaatcttg atggctgtca atgcgctttc ggatcaattg aagaaacaag
    15901 aaagaatatt ggagctggaa gaagaaacag cagaattaaa gaaaaaaatg atcaaattta
    15961 cagagcttga aaatcgtgtg aaacgcattg aagcaatcga gaacgaagct cgggaagtat
    16021 tgaaagaaaa tggtcaagca gatcatacca ttaaaaatca tgtggaagca caacagattt
    16081 taaacgagaa acgaaaagga caaattaaac aaaaatcttc taattaagat ccttttatca
    16141 aaataagaaa aatttaaaaa agttagaaga gaaaggaacg tagcatgctg agtttgctga
    16201 ttttattttt attgctaatt gcgttttttt ctggagcacg tcgcgggttt gctttgcaaa
    16261 tcatattcgc gattggatat gtattgtcat ttattgctgc ccagcatttt tacaaaccat
    16321 tagcaagtca tttggaatta tacattccat acccagctgt caccccaaca tcaaagttag
    16381 cattttttga tcaggtattt gcctttcacc tagatgaagc tttttatgca ggaactgctt
    16441 ttctgattat tttgctaatt ggctggctgc ttacccgatt tgtgggggtt tttgtccatg
    16501 gattgacgta tgtgccgatc ttgagacagg tagactggat tgcaggaggc atcctgtcac
    16561 taatcatggc ttacgttact atatttttga ttttgcagtt acttgccttt gttccattag
    16621 atgtggtcca aaatcaattc ggcgagcata gtttcgctcg ttttatcgtt gagagaacgc
    16681 catttcttac caacaagatg tatgagcttt gggtaacgaa tattttgaat taaggaaaat
    16741 agtgctggaa aatatttcgt tttttgtaca gagtagttta tttaagaagg ctgcgtagcg
    16801 tatgtccggc acagctcttt tttcatagtg aaagataagg tgataaaatg aataaccgaa
    16861 tccttgaaac attggaattt gaaaaagtca aacagatggt cagacaattt gtagtgactg
    16921 cacaaggaaa agaagaactg gcagaattgg taccagtgag tgagaaacaa acgatcacaa
    16981 actggcttca agaaactgag gatggattga aagtgcaacg tctgcgaggc gggatcccta
    17041 tacctaaaat tgaaaatatc cgtccccata tgaaacggat tgagatcgga gcagacttga
    17101 atggagtgga gcttgcacaa gtttccagag tattgtctac gacaagcgaa ttgaatcgtt
    17161 tcattgatga tctttctgac agtgaaatcg aatttgcacg tttgtatatg tgggcagatc
    17221 agttagtcac gatccctgtt ttgagccgcc gtttaaagga agcaatcgat gaagacggac
    17281 gcgtgactga tgacgcttct cctgagttaa agagcataag acagaacatt cggcgaagtg
    17341 aacaagctgt tcgtgaacag ttagatggga tcgtccgtgg gaaaaatgca aagtatttaa
    17401 gtgatgcgat catcaccatg cgaaatgacc gctacgttat cccagtcaaa caagaatacc
    17461 gcggtgtatt tggcggtgta gtccacgatc aaagtgcttc aggtcagact ttatttattg
    17521 aaccaaaaca agtggtggat ttgaataatc gtttgcgtca ataccaaatc gctgaacgaa
    17581 atgagattca acgtatttta agtgaacttt ctgctgaact tgttccccat cgtcaagaaa
    17641 tcatccacaa tacttatgtg attggtaaaa tggatctgat gaatgcaaaa gcacgatttg
    17701 gtaaagaagt aaaagccatc gtgccgggaa tcagtgaaga caatcatgtc gtcttgaaac
    17761 aagcaagaca tccactgatc gatcaggaaa aagtagtttc taatgacatc acaatcggaa
    17821 aagactatca agccatcgtc attacaggac ctaacacagg tgggaaaacg atcacgttga
    17881 agactttagg tctgttacaa ctgatggggc aagcaggatt accgattcct gcaggtgaag
    17941 aaagtcaaat cggtattttt gaggaagtat ttgcggatat aggagacgaa cagtcgattg
    18001 agcaaagtct atcgaccttt tcttctcata tgacgaacac tgtagatatt ttatcaaaag
    18061 tcaatgaaaa aagtctggta ttatttgacg agctcggtgc aggaacagat ccgcaagaag
    18121 gtgctgctct agcaatcgca atcttagatg atcttggtaa aaagtctgct tatgtgatgg
    18181 caacaacgca ttatcctgaa ttgaaagttt atggatataa tcgggcaaat acgattaatg
    18241 ccagcatgga gtttgatgtg gatacattaa gtccaacgta tcgtttgctg attggcgttc
    18301 ctggacgaag caatgcgttt gaaatctcta gccgattagg tcttgataca gaagttattg
    18361 atgaagcgaa gcagttgatg aatgatgaga gccaagattt aaacgaaatg atcacagatt
    18421 tagagaatcg ccggaaaatg gcagagaccg aatatctgga aatgcgtcat tttgtttctg
    18481 aggcacaaga acttcacgat gatttgaaag aagcttacag ctatttcttt gaagaacgtg
    18541 aaaaagaaat ggaaaaagca aagaaaaaag caaatgaagt cgtgtcagag gcggaagaaa
    18601 aagcagaaaa aatcattgct gatattcgta aaatgcaaca gcagattggg caaggaaatg
    18661 tgaaagagca tcagttgatc gatgcaaaga cccaattagc aaatctacat caagaagaaa
    18721 ctttgaagaa aaataaagta ttgaagaagg cgaaagaaca aaaaacgttg aaaccgggag
    18781 acgaagtgtt ggttacgact tacggccaaa gagggacgct tttacgtaaa aacgggaatc
    18841 agtggcaagt agaaatcggt atattaaaaa tgaatgtgtc cgaagacgag ctgacgcctg
    18901 ttgctcctca aaaagagccg acacaacgag ttatccatgc tgtacgatct gaatctagta
    18961 gtcacgtgcc gaatcaattg gaccttcgag gaaaacgata cgaagaagcg ctaagtgagg
    19021 tagatcaata tttggattct gccattctag ctggttatcc tcaagtgact attgtccacg
    19081 gaaaaggaac aggcgcactt cgcaagggaa ttactgatta tcttaaaaac catcggagcg
    19141 tcaaaagctt tgagtttgca ccggcaaacc aaggcggaaa tggtgcgaca attgttaaat
    19201 ttaagtaaag cttactaaag gtaagcagat ggttcgctat ccaagtatag aaatgctata
    19261 ctagtcatag attttaaaaa tggaggtctt tgatatgtca caagtaatta cagataagac
    19321 atttaatgaa gaaacagata aaggacttgt attgattgat ttttgggcaa cttggtgtgg
    19381 tccatgtcgt atgcaagcac cgattttgga tcagttggaa caagaatatg atgaagaaga
    19441 attcagaatt gctaaaatgg atgtggatga aaatccagaa actcctcaac aattcggtat
    19501 catgagcatt ccaacattaa tgttgaaaaa agatggtcaa gtagtagaaa aagctgttgg
    19561 tgttcattca aaagaacaac tacgtcaaat gatcgatcaa tatttataaa aacttacagc
    19621 aaaaataagc tgagggtggg actgaatcca gttccgtcct cggttttttt gcggttgagt
    19681 taaggttatt caaattaata ttttttgagt ataattacgt tgtcaggctg gattgttttt
    19741 ttgacagaca tgctataata actttaattg aatatgaagg ggagtaccag atgaacgaac
    19801 gaatcaaaaa caaattagct ttacttcctg atcagcccgg ctgttacttg atgaaagata
    19861 aaaatggaac gatcatttat gtcggcaaag ccaaaatatt aaaaaatcgt gtccgctcat
    19921 attttactgg tagccataat acgaaaacgg aacggcttgt tagtgaaatc gaagactttg
    19981 aatacatcgt tacagaatcg aatatcgaag cattgctctt agagatcaat ctgataaaga
    20041 aaaatgatcc taaatacaac attatgttaa aggatgataa aacctatcct ttccttaaga
    20101 taacgaatga aaaatatccc cgtttggtga ttactcgtaa ggtactaaaa gacaaagcac
    20161 tgtattttgg accatatccc gatgtcggtg cggcgaatga gacaaagaag atcctcgatc
    20221 gattatttcc tctgagaaaa tgcaaaccta gtcagacgaa ggagccttgt ctttactatc
    20281 atttgggaca atgcctgtgt ccttattatt tcgacgtaga tccgaaagtc tatacgaaaa
    20341 tcgttgatga agtgaaaaac tttttaaacg gaggacacga aaaaatcgag tcagagatcc
    20401 atcagaaaat ggaaaaagct gctgaaaaca tggagtttga aaaagctgca gaataccgag
    20461 accagatccg tgccattgag acaatcatga ctcgccaaaa aatgacaaat actgatttac
    20521 tggatcgaga tgtatttggt tatgcgattg ataaaggatg gatgtgtgtc caagtgtttt
    20581 tcgtaagaca aggaaagcta attgaacgag atgtttcaat gtttcctttc tataacgaag
    20641 cagaagaaga tttcttgact tacctcggtc agttttatca ggaaaatgag catttcattc
    20701 ctaaagaagt cttgattcct gatacgatcg acaagcccag tgtagaagct ttgttagcta
    20761 cgaaagtgct gcaaccaaaa cgaggagaaa agaaaaaatt agttgaattg gcgagtaaga
    20821 atgcctcagt tgctttgaat gaacggtttg atctgattgc cagaaaacag gaacggacga
    20881 tcggagcagt tgaacgttta ggaaacgcga tgaatatccc gaccccaata cgtatcgagt
    20941 cttttgataa ctctaatatc atggggacga atcctgtggc tgcgatggtc gtattcattg
    21001 atggaaaacc ggcaagaaaa gaatatcgga aatataaaat aaaaacagtc aacggaccgg
    21061 atgattatgc atcaatgaga gaagtcatct atcgcagata ttcgcgagtg attcgcgaag
    21121 ggttgccttt acctgatttg atcttgatcg atggaggaaa aggacaagta gatgtggcaa
    21181 aagatgtctt agaaaatcaa ttaggaatcg atattcctat tgctggcatg gtaaaaaacg
    21241 ataaacataa aacaaatgag ttgctattcg gtacagattt ggctgtagta ccgcttgagc
    21301 gaaattcacc agagtttttc ttactccagc gaatccaaga tgaagtccat cgattcgcaa
    21361 tcactttcca tcggcagcta cgcagtaaaa acagttttgc ttcccgatta gatgaaattg
    21421 aagggttagg accaaaacga aaaaaaatgc tgcttaaaga gttcaaatcg ttgaaaaata
    21481 tcacagcagc cacgacagaa gaattacaag aaatcggact gccgaaaaat gtcgcacaaa
    21541 acgtatttga taaattacat caggaatgag gaaagggcac tttacaaaga aagtaaagtg
    21601 tcctatcatt ttatgtacaa caaaaagagc gtttacgttt tgttggtaaa taataaatcg
    21661 cttacgtctg gtgtctaagg atatatgtga tttcttgaag aaggagtgaa gaaatgttag
    21721 aagtcaagga tcttgttaaa acttttggga actacacagc tgtcgatcat gtctctttcc
    21781 aaatccccga tggaaaaatc atggggctaa ttggccaaaa cggggctggg aagacaacga
    21841 cttttcgttt gatcttggat tttttgacac aagaccaagg agaagtgtta tggaatggcc
    21901 atcatcttgg ggagaaagat tatgatgtca tcggttatct tccggaggaa cggggacttt
    21961 atccgaaagt aacgattcaa gaccaactgc tttattttgc agaacttaga gggaaatcaa
    22021 gaaaagagat tgaaccaaaa atcgactttt ggatggaaaa atttcaggta aaagggaaaa
    22081 agacggataa agtaaaatct ttgtctaaag gaaatcagca aaaagtccag ctgatcgcca
    22141 cgttaatcca tgaacctaaa ttgatcattt tggatgagcc attcagcggg ttagatccgg
    22201 taaatgctga attgctaaaa gatggaatat tggaattgaa aaaacatggt tcatgtgtca
    22261 ttttttctag ccacaatatg gataatgtag aaaaaatctg cgatcatttg atcatgttgc
    22321 gaaacggaaa aatggttttg aatggaaaag tacatgagat tcgtgaatca tttggccgta
    22381 cgaagttatt cttggaatct ggtttaagcc aacaggaagt agaagaaatc gaaggcgtga
    22441 aaaaagtgat ccttcatgaa gacaatacgt tagagattac cttagaagat cctgaagctg
    22501 ggaaagaaat ctttactcgt gcgactcagt tcggctacat tcctatgttt aaccagcaac
    22561 cgccaacttt ggaagagatt ttcaaattga aagcaggtga aatcgatgcg taagttttgg
    22621 attattacca aagatgtcta tttaaaaaat gttaagtcga tttctttctt gatcatgata
    22681 ttagtccctt ttatcatgct gggtatcatt tatgtagcag gaaactttgc tcaacaaaat
    22741 agtgatgtca ataaaatcgg cgtattggct gataatgagc aaatcagtca gcaaatgagc
    22801 caagtcaaaa cagatgattt tgagttcaaa gcagttgatt ctgaagaaaa agcacaaaaa
    22861 gagctttcgg aagaaaaaat cgatgcgtat ttagtagtct caactgagaa tgataagata
    22921 aatgggatgc tttatagcga aaattcatta ggacaaagta cacaactact gatacaacaa
    22981 caactgactg gcttgcaatc gatgcttcga gcgagtcaat taggcatttc accagaagaa
    23041 gtagctagct tgagccaaca agcaagtttg actcgacaaa aagtcaattt tgattcaaaa
    23101 ggaaaaatga cagtcggaga agataactcg acagtccaat acgtcgtaag ttatgtagca
    23161 acgattgtct tgttcattat tattttgacg tatgcgcaga tcattgcaca agagatcgct
    23221 tctgaaaaag gcacgcggat catggaagtg atcctgtcca gtacgactgc acaaaagcat
    23281 ttttacggaa aattaacagg tgttttactt gttgcattaa cgcaaatggc attatacggt
    23341 attatttttg gtataggata cagtcaattc aaagatatgg aaatggtcaa aaatatatta
    23401 gacggtatct cattggataa cttgattgga ccattcttgt ggtattctct tctattcatg
    23461 atctttggca ttttgatttt ttctgtttta gcagctttat gtggctcttt ggtcaacaaa
    23521 gcagaagata cagcaaaagc aattttgcca gtgacttatc tatctctagg cggatacatg
    23581 cttggattga tactaggagc ttcagatcca aacaatatcg ttattcggat cacttcgtat
    23641 attccattct tatcttcata tattatgccg attcgcttag caaatgagac agtcggtatg
    23701 ggtggagcat tgatttcctt gttggtactt gtagccgtaa cattcttatt gatgatcttg
    23761 tctgcaaaca tgtacaaatc gaatgtactc gtttatagcg aaggcggatt atggagttca
    23821 ttgaaacaat cgatttcaat tatgaggaat gaacgaaaaa aagcataaaa caatcctaaa
    23881 atacagaagg aagctggaca tctattgttc ccagcttctt tttgtataga cctattttat
    23941 ttattttact atattggata tatattcatt gaaaatagtg tataacaact ttataatatt
    24001 gagtatacca atttttggag gcgttttaat ggaccgttat ttagatttac tttcagaaaa
    24061 attcccctca acggaggatg tcatcacgga aatcatcaat ctcgaagcaa ttttgcagct
    24121 tccaaaagga acagagttat ttttgagtga tatacatggc gaatttcctg cttttgatca
    24181 tattctgcgt atcggttcag gaaatcttaa agaaaagatc aaagaccttt tttctgaaca
    24241 aatgacggaa acggatatca gccaattcac tatttttacg gcttatccag aatatgcatt
    24301 aacgactgat tggtacaaag aacaagataa atcgcagctg atccatcatt tgatcgatct
    24361 tttacggttt acgacagtca aatatacccg gtcaaaagtt cgaaaaggat tgccgaaaga
    24421 atatagctat atcattgagg aactcttgta tatcgatgac cgtatcaatg gaaaaaaaga
    24481 ctatgtaaaa aaaatcattg aacaacttgt tttgatgaag gaagaagaaa aatttttaac
    24541 gaaacttgca cagacgatcc aaaaatctgt catcgatcat ttgcatatcg ttggagatat
    24601 ttttgaccga ggaactcaag cagccaaagt gatggatcga atcatggatt tttcttctgt
    24661 agatatccaa tggggaaatc atgatatttt gtggattggt gcgtattgcg gctctgaggc
    24721 atgtttactg acacttttac ggattgcagc acgctataat tatttatttg aattagagaa
    24781 agaatatggg ttgaatttac gtccattgtt ttcttttgct catcaaactt atcagaagaa
    24841 tccagtattt gcgcctaaaa acagtaaaaa tctatccgaa agagagcaag aagaattaga
    24901 aaaaatccat caggcacttt ctatccttca attcaaatca gaacatcagt tattggatcg
    24961 tcgacctgaa tttaaaatgg acgatcgtaa attgctggaa aaaatcgact atgaagcatc
    25021 aacgattgat ttagaaggtc agctctatga gttgaaagga acttgttttc aaacgatcca
    25081 gccagatgat ccaaaaaaat tcttggaaga ggaacaaaaa gtgattgata gtttgatgta
    25141 ttcattccag cactctttga gaatgcaaaa acatatgacg tttttgatcg aaaaaggggg
    25201 aatgtatctc acgaacaatc agcatgtgct gtttcatggc tgtatacctg tagacgagaa
    25261 gggacagctc ttagcatttg aattagacca atcttatcgc ggaaaagaac tgctgggctt
    25321 ttttgaaaaa cagataactg aaagcgcaaa agatctgact gcaaaagaag atttagcaac
    25381 cgatttgatt tggtatgcgt ggagtgggcc attttcgcct ttattcggca agagtaaaat
    25441 ggcgactttt gaacgttatt ttctcacaga gcctcatacg cacgtcgaga aaagcaatcc
    25501 ttattatcac ttgcgagatg aagagtggtt cagtgaaaaa attttagcag aattcgacac
    25561 aaaagaagaa gggtcagcaa tcattaatgg gcacacgcca gtaaaagtaa aaaaagggga
    25621 gtcaccgatc aaagcaaatg gaaaagtatt tgtcattgac ggaggtttat ccaaagctta
    25681 tcaaaaaacg acaggaattg ccggttattc actattatgc aattcttatg gtttccaaat
    25741 cgtgacacat tatccgtttt tgcctattga acaacaattt gcaaaaaaat ccgaccaaac
    25801 aaatgtgaaa aaagtaatcg aacagcaact accacgcaaa ctcaatcgtg atacaacaaa
    25861 aggtatggaa ctgcagcagc agattaccca gctcaaaagg ctgttggact atcgaaagga
    25921 cgattgagaa gaattccagt gaacattgtt ccatagactg gagactgaga caaaagtcgt
    25981 gtcgcagtct ctttttccgg ataaacggtg ttcttctgcc aactcctcgg tcacaagtca
    26041 cactattcaa caaacatgaa aagctgtttt ttgaaattgc tccttgtgac tcagagttga
    26101 acggcaggct cacgacctct tggtataaac ggtgttcaaa agccagtttc tcggtattaa
    26161 gccaaattta tgcaaaaatg tgaaaagcca ttttcacaaa atttttctta atactcgaaa
    26221 ctaaacagct ttttcacaac cccctcagaa agtctattaa aattcattca caaagaaatc
    26281 gaataagcgc tgttcagatg gatgtacacg gtgggtaagt tccggatgcc attgaacacc
    26341 gaggatttta tgcatatcat ctttgctttg aaccgcttca acgagtccat cgttagaaaa
    26401 agcgatggct tttaataaag gtgaaagatc tttgactgcc tgatgatggt aagaattcac
    26461 aaaatatgga tcggggagaa ggttgcttaa caaactgtct gaaacaatct tgacttcgtg
    26521 agtcgtaaat tgcggggcag tgggctgttg ttcatgtttt actgaccact ttggatataa
    26581 tgaaagatct tgataaagtg taccttccaa aacgacattc aatagttgga gtccccggca
    26641 gactgcaaaa attggttttc tttgtttcaa tgcttccaag atcagtgcct gttcaaattg
    26701 gtctcgttga atatttgttt ccgttagctt tggatgagga tcttccatgt aaagttgtgg
    26761 actgacatct tgaccacctg caagaataag tttgtcgatt tgtccaatca gttgaggagc
    26821 tgaatctgga gacatgactg gcagaataag aggcaatcct tgagcatcta aaactgcatc
    26881 cacgaatcct tgcggtgtat agctcacttg atttccttgg aaagtatctg ttgctcgaat
    26941 cagttgattt ccggcaatgc cgatgattgg tttcatttgt attcccccta aagtagactt
    27001 attgtaacaa ggatttaaaa aaaattaaac tatgtaagac ttgcccctat acttatctgt
    27061 tcttgctgtg ttactatctg taaagagaaa tttcgtgtga aattcatgac gatagttgaa
    27121 aatattgctt aatttgttat aataaaaagt aagcagaaat aaaaaggttg ggcgtaagct
    27181 tcaaggatct agttcttcaa ggggtgagaa ggacatttta ttgaaggggc ctgcctatac
    27241 taagttatct ttagaggtac atactttcaa tgaaaaaaga aagcatgtac ctctttttta
    27301 aatcgaaagg aagtgaagca agtgttagaa gctttggaac aaatccgaaa agcagaagaa
    27361 gaaaatgaaa agcgtgctca aacactgcgg cagcagctga agatctatgc aacagaaaaa
    27421 gagcaggaat tggaaacgat ccaaacaaac tatcgacaac aactaaaaca gttggtggaa
    27481 gaaaaagaac aatttgaaat acaagaatta gaaaaagaaa aaatgaaatt gaaagcagaa
    27541 gcagacaagg tgcaagcaac tttgaaagat caatatcaaa agcatcagag tcaagcgatc
    27601 ggtgcgatca ttgaaagggt gaaagaaact tatggccgtc actaagatgg aaaaagtgac
    27661 cctcatttca gataaaagaa atcaggagag gattttacaa gcagtacaag gaatccaaaa
    27721 cgttgaaatc cgggatctgt atcaaaatag aacaaacaac cagtgggtgg agaagtattt
    27781 tccagatacc acgattattg ataaagaagc aaaattaagc gctttaggta atcggttgaa
    27841 agacatccaa gaagctatcc aattcataca acaccacggc gatagccgtc aaaagaaact
    27901 ccatttgaaa cgtcaagaac tttccttaca agatttggaa gccaattatt ccgaagaaaa
    27961 tttcataaat aaattgaaag aagtccttga tttaaaagaa aagtgggaac aactaactga
    28021 agaacgtgat cgtttagaag aagaggaaga atggcttctt cattggcaac agctggatat
    28081 tgctccaagt atgtatgcaa gtaagacgac catttttgag atggggactg tgagtgcagc
    28141 aaattttgaa agtttcaagg aagaactgag taagcttgat gacgtttata tggaagaaat
    28201 agattatacg ccaaaacaag tttatctttc gtatgttgct ttaaaaaaat cagttgctgt
    28261 tatagaagaa attgctggga aatacgggtt caataaagaa acgtatcctt atgaacaaaa
    28321 tcctaaagaa aaactgcaag agaccaagca gcaattatcc attgttcacg agcagcaaaa
    28381 gaagataacg acagcgttag gtcagtgcag tggctatatc caagaatttg aatgggtaga
    28441 agaagtcaca cttgccgttg cagaacgaga aaaaataaaa gaacggttta tccatgcgac
    28501 ttatctgatc gttttgcaag gttgggtaga tgcagaagaa aaacagaatt tgctgcatgt
    28561 gttaaacgaa accgtatcag aagaagatat atacgtcagt ttcgaaacac caaactcaga
    28621 agagattcag caggaagtcc ctactaaatt gaaaaaccat ccgcttgtcg aaccttttga
    28681 attgctgact gaaatgtaca gtctgccaaa atatgaagaa gtagatccaa caccttggat
    28741 gacaccattt tatcttgtct tcttcgggat gatggtcgca gatgttggtt atggtttgct
    28801 gatgctcatt gggacaatac tagctcaaaa actacttgtt ctaccacgcg ggatgaaacg
    28861 tttcgtaaaa ttctttgaga ttctctcgat accatcgatc atctggggat tgatctacag
    28921 ttcatttttc ggacagtcat taccaaaaga actgtttggc atccgcttgc ctttcccaat
    28981 cctatctacg acggatgacg tcaatacgat tttgatttta tccgtgattt tcggtctgat
    29041 acagattttg gttggattat ttgtggcagc aaaggaaaat atcaggagaa aagattactt
    29101 gagtgctgtc agtgatggat ttgcctggca agggatccta attgggatcg ttattgcgtt
    29161 ggttggtgcc atgttgataa aaaatacagc atttgtttac cttggcgctg ggctatcgat
    29221 cattgctgcc ttatgtatct tgatcgttcc gattatccaa acgccgtcta aagtcaaagg
    29281 tgctgccaaa ggtgcgtata atctttacgg actgaccggc tatatcggtg atttagtcag
    29341 ttatacacgt ttgatggcat tgggtatttc aggcggaagt attggagcgg cattcaatat
    29401 gctagttgct ttcatgccgc cagctgctcg attcagtgta gggatccttt tgatcatcgc
    29461 tttacacgca ctgaatatgt ttttgacact gctaagtgcc tatgtccatg gcgcacgatt
    29521 gcagtatgtc gaattttttg ggaagtttta tacaggaggc ggacgtgcct ttgatccgct
    29581 gaaaacggcg gaaaaatacg tcaacatcaa tcacaagaaa aaaaacaata aataattgga
    29641 ggatttttat ataatgatgg attacttaat tagtcaaaat ggtggaatgg tatttgcggt
    29701 attagcgatg gcaacagcga cgattttttc agggatcggt tcagctaaag gtgttggaat
    29761 gacaggtgag gcagcagcag cattgacaac aagtcaaccc gaaaaattcg ggcaggctct
    29821 gattctgcaa ttgcttccag gcacgcaagg tttgtatgga ttcgttattg cctttttgat
    29881 ttttatcaac ttaggaaatg acatgtcagt tgtacaagga ctgaactttc taggtgcttc
    29941 tctgccgatt gcttttacag gcttgttttc aggtattgcc caaggaaaag tcgcagcggc
    30001 aggtattcaa attttagcga aaaaacctga acatgctaca aaaggaatca tttttgctgc
    30061 gatggttgaa acatacgcga ttttaggttt cgttatttcc ttcctattag tgttgaatgc
    30121 ctaagcataa aggaggaaaa gcagatgaac gccattgaaa aaatcatctc tcagatgaac
    30181 gaagcagcag agcaggaaag agcggcgtta gaacaagaag agcgaatgaa gatcgatcaa
    30241 aactttgaac aaaaacgtac gcaagttgaa acagaacatc aaaaacaaaa agaaaaacaa
    30301 atcgaattac tcgaaaaaaa ataccgtcag ctaaggaatc gccagcaagt agaagtacga
    30361 caagaaaatt tgaatgcgaa gcaggaattt ttaagacgat tgtttgcaga tgcggtaact
    30421 gaaatggaaa attgggatga atctgaacaa atccagttta tcaaaaatgc attgtattca
    30481 ttacctttga caggaaaagt agcattcatt gctggagaaa aatcagcagc ctatctttct
    30541 cagacgttgt tggatgaatg gaacaatgaa cttcccttta tgatggtttt aagtgatgaa
    30601 actgttgctg atcaagcggg ttttctgata aacgatcaag gagttcagta taattttctt
    30661 ttcagcagcc ttgtacaaga tatccaagga acgatgagtt ttgagattgc caatcaatta
    30721 ttcgaataag gagggatcag tgtatggaat accacgaact aaatcccttg attcgcggaa
    30781 gagagcttga acttttgtcc aatgagacat ttgaacggat gattcaaaca aattctgtcg
    30841 aagcacttgg tgaaatattg aaatccacga tttacagtcc atatatttat gacggatatg
    30901 aatatgactt cgaacagaat cttttaaagg agcagagccg tctatttcgc tggttaaagg
    30961 aatcagcacc ggagcctgaa atcgtttgga tctatacgat gcgttatact ttccataatc
    31021 tgaaggtttt gacaaaagct gagatgacaa atcaaaatct ggaccatttg tatatcgacg
    31081 atggatttta ttcattagaa accttgaagg atgccattca tacgcaagtt tcaaatgaac
    31141 ttcctgaaag cattatggac agtatacgag aagtacgtga ttattttgaa gagtctacca
    31201 ttcttcaggg aattgacgtg atttatgatc gacagttttt gacagagcag cgacggcttg
    31261 ccgataagct aggatatcaa gaattgctga cagaagtcat tgcttttatt gacttgacca
    31321 atatcacaac gatggctcga ggaatattgc agaaaagaac atatgggttc atgacgacgg
    31381 tactttccag ctcgggaagt atcgaaaaag aagtattttt gaactttgta gataaagata
    31441 tggaagatta cacgaatttt ctattagaga cagattatgc tgattttctg cgccctgtca
    31501 tccgtgaggg aaatattgat ctcgtaaagc ttgaacagtt gaaagatgat tatctaagtt
    31561 cattgtatca agaagcacaa acccaggctt tcggaccact gccactacta gcctttttga
    31621 acgcaaaaga ggtagaaagc aaaaaccttc gtttactggt tatcggcaaa agaagccatt
    31681 tcgaatcaga aacaatcaga aagcgggtga gacaagtcta tgacgcataa gatcggtgta
    31741 gttggcgaca aagattctgt tttgccattc aaattgtttg gctttgatgt tcgttatggt
    31801 acaaccaagc aaaccgttcg tcaggcaatt gaagaaatgg caaagaatga gtatggcgtg
    31861 atttatgtca cagagcaatg tgcagcattg agcccagaaa cgatcgaacg ttacaaggaa
    31921 caaatgatac ctgctatcgt attgattccc aatcatcaag gatcattagg gatagggctg
    31981 gaagaaattc aaaaaaacgt agaaaaagca gtaggtcaaa atatcttata gtatgaaaag
    32041 gagatagaaa ttttgcaaat tggaaaaatc ataaaagtct ccggacctct tgtaatggct
    32101 gagaacatgt ctgatgccag tatccaagac atgtgtctag tgggagatct aggagttatc
    32161 ggagaaatta tcgagatgcg tggcgatgtg gcgtctattc aagtatatga agagacttct
    32221 ggaattggtc caggcgaacc ggttcgctct actggtgaag ctttatctgt tgaattagga
    32281 ccagggatca tttcacaaat gtttgacgga atccaacggc cattagatac ctttatggaa
    32341 atcacacaaa gtaatttctt agggcgcgga gttcaattgc ccgcattgga ccatgagaaa
    32401 aaatggtggt tcgaaccaac agtagaagcc ggagaaacgg tgagtgctgg agatgttatc
    32461 gggatcgtag aagaaacaaa agttataaaa cataaaatca tggtgccaaa tgggataaaa
    32521 ggaacgatca aaacaatcga aaaaggttca ttcactattg atgaaacagt atgtgtcatt
    32581 gaaaccgaaa atggtgacaa aaatttgacg atgcttcaaa aatggccagt aagacgtagt
    32641 cggccaatca aagaaaaatt aaacccggat gcacccatga tcactggaca gcgagtgatt
    32701 gatacattct tcccagtgac aaaaggagga gcagcagctg tacctggtcc ttttggtgca
    32761 gggaaaacag tcgttcagca tcaaattgca aaatgggccg atgtggacat ggttgtctat
    32821 gtgggatgtg gcgagcgtgg aaatgagatg acggatgttt taaatgaatt ccctgaattg
    32881 attgacccta atacaggaga atcgttgatg gaacgtacgg tattgattgc taatacatca
    32941 aacatgccag tagcagctcg agaagcttct atctatacgg gaatcacaat tgcggaatat
    33001 ttccgtgaca tgggttatga cgttgctatc atggcagact ccacttcacg atgggcagaa
    33061 gcacttcgtg agatgagcgg acgtttggaa gaaatgcctg gtgatgaagg ttatccagct
    33121 tatcttggtt cacggcttgc ggaatactat gaacgatctg gaagagtcat tgcattagga
    33181 tcagaaggtc gcgaaggaag tataaccgca atcagtgctg tatccccgtc tggaggggat
    33241 atttcggaac cagtcacaca aaatacattg cgggtcgtaa aagtattctg gggtcttgat
    33301 tccagtttag cccaaaaaag acattttcct tcgatcgatt ggatacaaag ctattctctt
    33361 tattcaacag aagtagggaa gtatatggat catatccttc aagctgactg ggcatccatg
    33421 gtcaccgagg gcatgcgtat tttgcaggaa gaacagcagc tgaatgaaat cgtgcgtttg
    33481 gtagggattg attccctttc agataatgac cgtctgacat tagaagtggc aaaatccatt
    33541 cgtgaagatt atttgcagca aaatgctttt gatgatgtcg atacattcac ttcaagagag
    33601 aaacaattca aaatgttgaa gatgatcttg acctttggtg aagaaggacg ccgtgcgttg
    33661 tcgttaggtg cttatttaag tgagatcatg gacggtaccg tatcgattcg tgaaaggatc
    33721 ggacgaagca aatatatccc ggaaacagaa ttagaaaaac tagatcaaat tattggtgaa
    33781 atcaagcaaa cgatgcaaac gatcgtttca gaaggaggca tgagcaatga ttaaagaata
    33841 tcgtacgatc ggtgaagtcg tcggtccatt gatggcggtt gaaaaagttg ctggtgtcaa
    33901 atatgaagaa ttaatcgaag tccgtatgca aaatggcgag attcgtcgtg gacaagtatt
    33961 ggaagtccaa gaagataaag caatggtcca aatattcgaa ggaacaagtg gtatcaattt
    34021 acgtgactct tctgtacgat ttttaggcca tcctttagaa ctaggtgtat cggaagacat
    34081 gatcggtcga gtattcgatg gtttgggacg accgaaagat aacggaccag agatcctgcc
    34141 tgaaaagcat ttggatatta acggagaagt aatcaatcca gtagctcggg attatccaga
    34201 tgagtttatc caaacaggta tctctgcaat cgatcatttg aatacattag ttcgtgggca
    34261 aaaattacca gtattttctg gctctggtct tcctcataaa gaattagctg ctcagatcgc
    34321 gcgacaagca acggtactcg attcatcaga tgatttcgcc gtagtctttg ctgctattgg
    34381 aatcactttt gaagaagctg aatttttcat ggaagatttt cgtcaaacgg gcgcaatcga
    34441 ccgttctgtc atgtttatga atttagcaaa cgaccctgca atcgaacgta tcgctactcc
    34501 tcgtatggct ttgactgctg cagaatatct tgcttatgaa aagggaatgc atgttttggt
    34561 tatcatgaca gacatgacca actatgcaga ggcattgcga gagatttctg cagcacggcg
    34621 agaagttcca ggaagaagag gatatcctgg gtatctttac acgaacttag ctactttatt
    34681 cgaacgagca ggaagaatcc gcggactaaa aggatcggtt actcaaattc cgattctaac
    34741 aatgccagaa gacgataaaa ctcatccaat ccctgacttg actggttata ttacagaagg
    34801 acagatcatc ttgactagag agctttacaa gagtgggatt cagccaccaa ttgatgtact
    34861 cccgtctctt tcgcggttaa aagataaggg aactggaccc ggaaagacaa gagaagacca
    34921 tgcagctacg atgaatcagc tttttgcagc ctatgcacaa ggaaaacagg caaaagaatt
    34981 agccgtagtt ttaggtgaat ctgctttatc tgatgtagac aagatctatg cgaagtttgc
    35041 tgagcggttt gaaaaagaat atgtcaatca aggattctac acgaaccgtt cgattactga
    35101 aacacttgat ctagggtggg aactgctatc gatgttgcca agaaccgaat taaaacgaat
    35161 caaagacgac atgctggaca aatatctgcc agaagggaag tgagttctga tggcacgatt
    35221 gaatgtgaat ccgacccgca tggaattgac tcgattgaaa aaacagttga caactgccac
    35281 aagagggcat aaattattaa aagataagca agatgaactg atgcgtcaat tcatcctgtt
    35341 gattcgaaag aacaaccagc tgcgtcaaga aatggaagag tctatgacag aagcaatgtc
    35401 tgattttgta ttggcaaatg cttcgatcac ggaacctttc atcgaagaat tatttgtttt
    35461 gccggcggaa aacgttgatt tgtctatcgt agacaaaaat atcatgagtg taaaagtacc
    35521 tgtgatgaat tttgaatatg atgaacagct gacagacaca cctttggaat acgggtattt
    35581 gaattccagt gccgaactgg atcggtcaat cgatcggttt actaccctgc ttccaaaact
    35641 tttggaactg acagaaatcg aaaaaacttg tcaactgatg gcgagtgaaa tcgaaaagac
    35701 acgtcggcga gtcaatgcat tagaatatat gacgatccct caattagaag aaacgatcta
    35761 ttatattcgt atgaagctgg aagaaaacga gcgcgcagaa gtaacaaggt tgatcaaagt
    35821 aaaaaatatg ggtaccactg actaagtggt atcttttttt aaaagaggaa aacgatgatt
    35881 aaacaaagca aacaaataaa gaaacgtttg ccggctgttc agcttctcgc attaggattt
    35941 tttctcctga ttttagttgg cggcggccta cttaccctac cattttttag taatagtggg
    36001 catgggacaa attttatcga tgcgcttttc actgcaactt ctgctgtctg tgtaacggga
    36061 ttgacaacat tgaatacagc agagcattgg aacagtgctg gtcaattttt gatcatgctt
    36121 ttgattgaga tcggcggtct tggttttatg atggttccga ttctatgctt tgcattgata
    36181 aagaagaaag tcagtctcag cacacgtatt atattaaaag aagcgctgaa tctagaagaa
    36241 gtatcaggtg tgatgaagct catgctttac atcctaaaat tggcctttgt gatccaattg
    36301 attggtacgg ttgctttatc ttttgtattt gtgcctgaat ttggctggtt gaaaggtatc
    36361 tggtacagtt tgttccatgc aatctctagt ttttgtaatg cagggtttga tttgttagga
    36421 gacagtttag ccaatcacca gcaaaatgtt tatttgatca tggtggtatc tgctttgatc
    36481 atttctggtg ggttaggctt catcgtatgg cgtgatttac tggaatatca tcagaaaaag
    36541 aagatgacga ttcattcaaa aatcgcatta accgttacag gtaccctttt attaggcgga
    36601 ttcgttgtgt tctttttcac agagcgcaat ggggcaacgc tagtggaagg gaatatgttt
    36661 caacgattgg caaacacctt ttttatgagt gtgacaccta gaacggctgg atattattca
    36721 gttgattacc tccatatgag ccatgcaggt ctgattttaa cgatgttttt gatgtacatc
    36781 ggcggaacat ctgggtcgac ggccggcgga ttgaaaacaa ctacgttagg tgtgttgctg
    36841 atccagatgc gttcgatgtt gaaaggacgt acgagagcgg aagcatttgg ccgtaccatc
    36901 cgacaaggcg cagtgttgcg ggcacttact ttattttttg ttacgttgac gttgtgtgta
    36961 gtcgccatca tgattttatc ggtgactgaa acgataccta aaacttctgg catcgaatat
    37021 attgcttttg aggtcttctc tgcgtttggt acagtaggtc ttacgatggg attgacgcca
    37081 gacttgactg caatagggaa attgatcatt atagcgctta tgtacattgg acgagttggt
    37141 gtattgactg tggtcttctc tctgatgaca aaagcacaaa gaacacaatc aaaatacaaa
    37201 tatccagaag aaagtgtcat gattggataa tttcatcttc tgacagaaac ctagtgattt
    37261 agtaaaataa gaaaataaaa taatttttct tgcttcttgg atactttaag tgcaaaatgt
    37321 tcgtttattt tttgaggcac tacccgttgt tgaacctcgg gtagtgcctc ttttttattg
    37381 aaaggaatca ataagatttg attcctttat ttatcaatag gttataattc atattttttt
    37441 attttttctt ttacgatact tagtccagaa gctaaaattt caaggttatt agaggatagg
    37501 gaaattcgaa cgaatgcatc tggttgcgca cgtgtagtaa agcgtctgga atgataaagt
    37561 cggataccgt tagcaagaaa gtcattctca attatcttag ggtcaatctc aggatcaact
    37621 ggaagaattc gatagtaagg gacacgattc gttggttttt ctactttgaa aagagaatca
    37681 aaaagctgat tggctctttt tgtaagactt aatttagttt ctaagatcct atttgcttca
    37741 tttgaatgga ggatttgagt gatgacttcc acatctaatc cagaagtttt cacatttata
    37801 ttaaaaattg cttgttctat cttgctttgg acatgtactg gaactacaag ataagcaact
    37861 cgcaatccag aacaaataaa ttttgtcatt ccagctaagt agattgtttg gttaggtaat
    37921 aaattttgga aaggaggaat gatcgtatgt tgatagtaag ttgttaaaaa tgaatggata
    37981 tcatcttcaa taacccatag accttctttt tcaatcactt cggctaattg ctctcgtctt
    38041 ttgtgagaga tttgaaaccc tataggatta ttacaagaag gcataagaaa gacaccatga
    38101 atcttctttt ttctacattc ctgaatcaat atatcaggtc gcattccttg ctcgtcaaaa
    38161 tcaattggaa cgatctctaa atgatataac tgagccaatt caatgaaatt agcgtatgta
    38221 tatcggtctg ttgctattct atcacctgga gagaaaagtg cagaaagtgt gatagccaat
    38281 ccattttgaa caccggaaac aatagataga gattctaagg acggaatgac tccttgagtt
    38341 tttaaccaat ttgctgcagt agtcaattga aaatttgtgc ctttgggatc ttggtaatta
    38401 agcaaaccaa caagatttgg gttattacta gttgattgaa taaacgggac aacgaattta
    38461 ttacattctt caaaagaact aaccagacca aaatcaatga tatgttcggt tacttcattg
    38521 gtagagatgg tgatggactc aaagacattg ggagaaataa atgtgccact tccaatattc
    38581 gtatacagca aacctttctc aattccatat ttataagcct tgccaacggt agtaaaattt
    38641 aaatctaaat aatcagctag ctctctttgg gagggtaact gagtgttttt ctgtaattta
    38701 ttctttaaaa tatcttgttc taattgttga atcaacgatc gataataagg acgcttcaat
    38761 ttttgtttgt ctggtcgcca agttaacggg taattgtcat aagaattaat aggcattttc
    38821 tccactcctt aaaattgtat accatacaat tttaccattg attgtattga ttttagaagt
    38881 taatcttttg tgaggaggga attgtctatg aaaattatta attttgagga agtagtagct
    38941 tcttttagtt ttgaagaagc gattcaagta atgaaaaaat gtttttttga ttatgaaagt
    39001 ggtaaaatca gccaaaatcc tcgattggtg gaaattttac ctgacggaaa aggcaaaaat
    39061 atgtttgcga tgatgcctgc ttatttgggg gagaacagat attttggcac aaaagtcatt
    39121 accgcttttc cggataatca tcagtatcat ttaccttctc atttaggaga gattttcttg
    39181 tttgatgctc aaaacggact acccaaagca ttgataaacg caaatgcagt cacctggatt
    39241 cgaacagctg ctgtatctgc gctggcaaca gattacttag caaatccgca tgcagaaaca
    39301 cttgctttaa ttggagctgg tcaacaagca ttgtcgcatt tgactgcgat ttctaccatt
    39361 cgtcccatca ctacagtgtt tgtttacgat attttagaag aaagacgaaa tacttttatc
    39421 gctaaagcta aaaaacagta tcctaaaata acgtttataa atgcaatatc agtagaagat
    39481 gcagtacgtc cagcggaaat catttgtacg ttgacctcta gtaaagaggc atttcttcaa
    39541 aaagagtggg taagggaaga cgcacatatc aatgctgtgg gcacatttac tcctgataca
    39601 agagagataa gtacatcgtt gatggaaact tctcaaatct atgtagatga ttactcagct
    39661 gccttaacag aaagcgggga cctgcttata gccatggcag aaggagattt agaggaatct
    39721 tgtattgttg gtacattagg cgaattagtt tctgagaaaa aaacatttta taaaggagaa
    39781 tcgaggccga cgattttcga cgcagttggt ctagctattg aagatctttg ttgtgcagaa
    39841 tatatttata acaaattaga gaaaggggct ttaaaatgaa cttagattat tacgtagttg
    39901 atgcatttgc agatgaggtg ttcaaaggaa atccagcagc ggtttatgtg ctagaagaat
    39961 ggctgccaga aggtacgatg caaaaaattg ccattgaaaa caatttatct gaaacagcat
    40021 ttacagtgaa gaaaaaccaa gaatttgagc ttagatggtt tacgccagat cgagaaatcg
    40081 atctttgtgg tcacgcgaca ttagcaacag catttgtttt atttaactat tacaaaatac
    40141 ctgatgaaac gattaaattt tctactcaaa gcggtaatct atttgtgaca agaattaaag
    40201 attattatta catggatttt cctagtatta tgccgaaaaa agtgccgata ttgtctgaat
    40261 atgaagaagc gattggggct aagattaaag aagcctactt agcacgtgat ttatttttcg
    40321 tattagaaga tgaaaaaacg gtggctaaat tgcagccaga ttttacagct atcaaaaatt
    40381 ttgaattagg aataggagtc atcgtgacag cagaaagtgt gcaaaaagac tttgtttcta
    40441 gaaccttctt tccaaaatta acaatcaatg aagatccagt atgtggatca gcacattcta
    40501 atcttattcc ttattgggca gaaagaatga ataaaacaaa attgtcagct tatcaaatgt
    40561 catcaagggg cggggatcta gaatgtgaat taaaagaaga tcgtgtgata ataggaggaa
    40621 aagcagtttt gttttctaaa ggtacctcgt ttatttgatt tctttcaaat gaattaaaaa
    40681 taaattggtg gagagtggca accttatagc tacaatggtt gttaaaaaaa gacgcaaact
    40741 ttttcaattt aatgaaaagt ttgcgtctca ttttaattat tggtgtttgt tttttattca
    40801 atcaagagta aaatgcccca tactaactat cctcggatga cttcgatttt ataaccatca
    40861 gggtcaatga caaagtagta agaaggcgca gtgccaggta atccttttaa gtcagtaatc
    40921 tcaagaccag cagctttatg ttgctcgtgt aatttttcta gatcatcagc tgctatagcg
    40981 atatgaccat agccgtctcc tagatcatac gcaccatgat catagttgta agtcaactct
    41041 aattcatagt catccccagg aagtgtcaaa taaacaagtg taaatttgtt ttctggaaaa
    41101 tcacggcggc ggctttcttc aaaaccaaat gccttttgat aaaattcgat tgatgcttca
    41161 agatctttca ctcgaacaca tgtgtgagcc attttcatag attcatctct ccttttcctt
    41221 ttactcaatc ataacaaaaa gaagtaagga aatagttgat ttgtgcttgt tcatgagaaa
    41281 tttctcatgt aaaatggata gaaaataaaa ctgttaaggt ggaaactatt catggataaa
    41341 ccaatttttg gtgaaaaaaa gcaatttgct gattatcaaa cccgttatgc agcatatatt
    41401 gtcatagaaa gagatcagca gattgcagta atcgaggctc caaatggtgc tttttttctt
    41461 cctggcgggg aaattgaagg agaagagacg aaagaagaag cgattgtccg tgagctgata
    41521 gaagaaatgg gaattgtggc agaaatttct tcttatctgg gagaagctga tgagtatttt
    41581 tactcgaatt atcgtgcaac ttattattat aatccaggat atttctttgt tgctgattct
    41641 tggaagcgta taggagaacc aactgaaaag accaataaaa tttggtgggt gagccctcaa
    41701 gaagcgcttg tgaaattgaa acgtggtagc caccgatggg cagtcgagag atggatcgaa
    41761 aaaaataaaa actgaaagaa agcgagtaga tcagctttct ctcagttttt ttatttatta
    41821 cagtacatat tttttgattg cttcagctac accgtgctcg tcgtttgatg aagtgatgac
    41881 atttgctgct tctttgacaa gagaaacggc atttcccatt gctactccta gaccagcata
    41941 ttcaatcatg gataagtcgt tctcgttatc tccgatagcc atgatttcat cttgatcaat
    42001 accaaggtgc tgtgcgagat tcgcaactgc cgcaccttta cttgcttctt tatttagtac
    42061 ttcgaagtaa tagggcgcac ttttgaccgt tgtgtattta tcacggaaag tttgcggtaa
    42121 acgcgcaatt gctgcatcta aaatttctgg ttcgtcgatc atcatcattt tgacgatgtt
    42181 catgtctggt gtcatttctt caggtgttcg atattttagc ggcatcttga ctaaacttgc
    42241 ttcgtggatc gtataagcgc tgatatctcg attaggcgtg tagatcgctt tgtcatcgat
    42301 cgaatggaga tgactgccga cacggcgtgc cattacttcg atctctagga aatcttcatg
    42361 tgtcagtccg tgacgggcga tgattttacc tgatttcgtt tgttgtacga gtgccccgtt
    42421 ataagtaata acgtaatcat tatcttgaaa aaggttcaac tcgtttaact gttcctggac
    42481 acctggtaag ggacggccag tgcataaaac gatcgaaaca ccttttgcaa cagcagcggc
    42541 aatcgcttct tttacttctt ttgttacttc tcttttctca tttaataaag taccatcgat
    42601 gtcgatagcg actagtttga tagacataat ttcctccaat atattttaat ttatttcaat
    42661 caatgcgcca ttacggatat ggctggcaaa ttcttgataa gtttcgtcaa ataaatcata
    42721 atgatcacgc aaggacggat caaccatttc ttttggaaag aaaaatcgct catctccttg
    42781 ttcttgtccc gctaatgcag caacaagctg actaacctgt gataattcta tcaaagttcc
    42841 gtcatttcgc aaaatctcga tttgtgtgcg atgtctgcct tgttctgggc gataaaaatc
    42901 ataaggtaga tcgtagctag aattcacagc agtgtaataa acaggattat atccgacctt
    42961 ttctactaac aaagtgagtt cttggactaa ttttgaatcc cggttgccag aaaaagtagc
    43021 agatttcagt ggtttacgat tcaaaaaacg tttagctaaa tcatttaaaa taggatcagc
    43081 agattcagac cattgagtaa agtaagtgcc caagacccca tcatcaagtt tgaggtattc
    43141 ttctaaagta aagcttccgt caagaaatgg cagaagtaat tgagaatgga gttcaaaact
    43201 gctggcatct tcttgataca actcgtgtgc gcgatgaagc agatgctcca aaattacttc
    43261 cataccacgg gaaacaggat ggaagtacac ttgcacatac atttgatatc ggctaacgat
    43321 ataatcttcc actgcatgca tgccactcat ggaaaaagcg atcccgcctt cataaggacg
    43381 aatcacacgt aatattcggg taagatcaaa tgttccatat tctgttccag tgaaataagc
    43441 atcccgaagc aaatagtcca ttcgatctgc atcgatctga ctagaaatca tttggacaac
    43501 ttgtgggttg gggtaagttt tttggatcac actagctacc ttttcaggaa aaccttcttc
    43561 tactcggtta agaatctgat acacttctgt ttctggagaa gtgatgatct ctacagtgat
    43621 ggcttcatga ttcgtatgga agatatgttc aaatgtatga gagtaaggac catgaccgac
    43681 atcatgcaac agtgccgcac ataaagtcac cagccgttcc tgatcatccc agcctccgtt
    43741 gcctattttt tcttttgaaa aatttcgaga aaagatatcg cagattcgtc ttgaaatctc
    43801 ataaacgcct aatgaatgag taaaacggct atgttctgct ccgtgaaaag tgaaagaaga
    43861 agtgcctaat tgtttaatgc gtcgtagacg ttggacttct ttcgaattga tcaaatctaa
    43921 gattacttga tgctggacat ggatatagtt atggactgga tcacgaaaaa ctttttccat
    43981 aggcagcatt tgatatttat aaggggttgt cataatgtag ctcctttatg ttattacgtt
    44041 gttccattct ctggatttgg ttgttccatt gctccagctg gatttctttt tttagccagt
    44101 cggtagaatc ctgtaaatca cttgcagaat acagcttttc aaaagctttt gcaaatgctt
    44161 ctttgacttc ttttacaaaa aggggttggt caagcagttc ttcaagtgtt gccattgtag
    44221 caggatccac tgcaggatag ccatttgtac caaagtcttc ttttaaagca gattgataaa
    44281 atcgcttcat gacttgccca cgtttttcct gattaccgtt gacacttaag tacatcataa
    44341 cagaaatccc atttttgatc cgacgctgag cgataccggc aaattttttg ccatggatgc
    44401 ttaaatcata agttccagga caataagaat gggtgatttc gaatgcttgt atcggtgcct
    44461 ttggaaaagc gtatttagtc aataggagca tttgctcgta agcgtcatct atggttattt
    44521 tttttgtgtc actttggggg aaaatcaaag aaatattcaa aattccttca tctgatacga
    44581 tccctaatcc acctgaattt ctgatcactg gagcgtaacc tgcatcttcc agtgtttgga
    44641 tcccgtcact tagaaaagga gttcgaacat ccttcatacc taagatgact gtgcagtcat
    44701 attgccagaa atgtaaaaag atttgctggt gttctttaga atattccgtt aatatatctg
    44761 ttaatgcaaa aggggaaaag tcgttttttt gataaatgtg ctgatctagt cgaatcgcag
    44821 ggttcattca accggctcct ttgtataaat tcatattttc tacaatatta tactctaaaa
    44881 tcaaagagtt gttttggaaa aaaggttttc tgtaaaaatg gacaagttgg ttgacaaaac
    44941 aaaagaaact aggaacaatg tagctatgag aagtaaagga gaatgaataa tggaattatc
    45001 acaaggaaca ccgatttcaa tcaaattgcg tacaaaagta aaacagcaag gggaagtgca
    45061 agatttttat tttgatttga aagggcaaat ggtgacaatt ggcgatacgc tgtacatacg
    45121 ttataaagag attcaggagg agacgggcga tgagattcct gtaacgatca aattagttcc
    45181 agatggtcat gtacagctga tccgtgcagg agaaatgcgg atgcgtttga aatttggcta
    45241 taaagaacgg ttagaaacat cctatcgaac accatacggt atgatccaga ttgctacttt
    45301 tacgaaagaa ctgcatgtta gtttgaaaga ccgtcccaca gcagggaagg ttcgaatcga
    45361 ttatgatctg ttcatgggac cggaaaaaat cggcgaatat tatttgacct tggattttac
    45421 agcgtaaata taaaagaaaa gtttgatttt ttgtgtctga ttttgtatga taaggagtag
    45481 actgtgaaag gacgtgtcct gattggaaat tagtgtattt gaaggtgcaa acaaaagcga
    45541 attatcaatg atcgaagtag cacacgcgat cttagaacaa cgtggcgatg tcatggattt
    45601 ttctgattta gctaaccaga tccaaaacta tcttgggaaa tcagacagtg aaattcgtga
    45661 ttcactcgca caattttata ctgacttgaa tattgacggc agctttatct cattagggga
    45721 taatcgttgg ggcttgcgtt catggtatgc tatcgattcg atcgatgaag aagtaaacca
    45781 tggaatggac gaagaggatg aagatactcc acgtcgccgt aaacgcaaga aagtcaacgc
    45841 ctttatcaat gatgatgaag acgcgatcga ttacaatgac gatgacccag aagatacaga
    45901 tctgacagaa gaagatgacg atgatctgtt tgatgacgat gatgatgaag atgaagaaat
    45961 cgctgcttat aattctgact tgcaagaaat cggagcagat gacccgacag atgatgaaga
    46021 agacttgcca ggaaatatcg aagaagattt aagtatcata gacgaagacg atgatgatga
    46081 agattatgaa gaggaagaat tttctgactc tgaaaaagaa taaacattat tttcttacga
    46141 gaggttgtga cagagacgat cagcctatca gaataaggag gtgtgacacg atttttgtca
    46201 caccttcttt tttgtatata aaaatcccaa gtaaatacat aaaaaataaa aaaattgaaa
    46261 cttttagcgc accttgtacg tcatattaag tgaggcagaa aggagtggag aatgattttt
    46321 actggatata agaaaaaacg gcagatcgaa aaataccgtc acctgctgaa tggactcatc
    46381 gaaactgatt atcaaaaaat gttccgtatc acgatgaatt acgtacatga taaagaagag
    46441 gccttagatg tgatgcaaga tagttttcat aaagccctga actattttga aaaagaaaaa
    46501 gagatcgagc attttagtgc atggttttat cggatattga tccgcacggc attagatagt
    46561 tggcgcagac aaaaaaggac gcctgtggac ttatttgaaa ttcaagatat cccccaacag
    46621 ttacctttag aaacttccgt tgcagagctc catatgattt tagataaaat agacagtccg
    46681 gaaaaagaga ttctgatcct ctactttttt gaaggatttc gtttgaaaga aattgcgact
    46741 atcttggata tgaatgaaaa cacagttaaa acgaaaatgt accgctcatt gaatgcttta
    46801 cgtcaaatcc tagaatgaag gagagaagag tgccatgtat tcccaaaaag aaaatttaaa
    46861 aaaactaaag aaaacttata aagaacaagc aattcccaaa gggcttaaag aggagatccg
    46921 ccagcgtttt attatcgaag agcaatcatt tataaaagca aagcggagaa agagacgtct
    46981 ccaagggttc ggagtatctt tggctatcgt aatgattaca acaagtagcc ttctttttaa
    47041 tagtcaagtt cgaagctttg cagaagattt acccatctta ggatcagtca ttgaattgat
    47101 cttaggcgaa cgctttactg atcgatctga aaaaatcgat attcaggtac cgaagatcaa
    47161 tacacaaaat gagaaagaaa ataaaacaat tcatggatta aatcaaaaat actttcgcga
    47221 aggacaagca gattttgaaa aagctgaaaa agaatatgga aattttgaaa cggatcatta
    47281 ccaagttttg ggagattatc agaaaatcgt agacgataac cggtttctcg tgattgaaag
    47341 gcagatcacc caaacagcag cagatagcca tgttgaaaaa agatacgaca caatcgacaa
    47401 gaaaaacagt gtccagctct cacttccact tttattcaaa gatgacacct atctatctgt
    47461 tttgacaaaa gaagtcaaac ggcagatggc cgaacaagtc aaggaagatc catctaagta
    47521 ctattggact gagcaagata ttcaagaagg gacgatagaa aaaccaacac ttgttacgcc
    47581 tacacgaagt ttttatttga acaaagagca tcaattagtt ttgacttttt ctcaatacga
    47641 aattgctcct ggttatatgg gtacaccaga atttgtcatt cctaagtccg tgacaaaaac
    47701 gattttggca tcggaagatt atttggatca ttagacgaga agtagttgcg actagcagtt
    47761 tcaattttca agtaagtaca agtaaataat aagaagagaa aaagagaaag aagagatata
    47821 gtgaaaagaa attatttagt tatcagtatt attgctttat ccgtgctttt gtttttcgaa
    47881 attacttcgg tggcctcctt gatcaccgaa gtaaaaggac aaacacactc ttcggagcat
    47941 tcgtcacaat ctttcaaaca atcagaacaa tcaaccatta aaagccaatc aactgaaaca
    48001 gctaacgtca aagaagccat tcaagaatca gcggaaaagg tacaaagtca gtcatcacaa
    48061 tcaacacaag acagtacaaa aacgagccga gatccggctg tcaaaagcgt cgcaatcagc
    48121 tttgatgatg gaccaggagc gaccacaaca ccgcagcttc tgcgaatctt aaaagaaaaa
    48181 aacgtgcatg ccactttttt cgtcttagga gaaaatacgg cgcagcatcc tgaaatcgtg
    48241 aagcagacag ctgaagcagg gcacgagatt ggcaatcaca catacgatca tcagaatctg
    48301 gccactcttt ctgcccagtc gatgacggag gaagtgacga aagcagacac tgagatcaaa
    48361 aaagtcactg gcaaaacccc cacttttgtt cgtccgccct atggttctgt cacgaatgta
    48421 ggagcaacga tcatccagcg accgatcatc gaatggtctg ttgattcaga agattggaag
    48481 acaagaaatc ctgatttgat tttgcagaag atccaagcaa cagtatacga tggggcaatt
    48541 attttattcc atgatatcta tcctgaaacg attcgtgccg ttcctcaagt gatcgattat
    48601 ctgaaagagc aagggtatcg catcacgaca gttggggatt tattagggca tccaacggct
    48661 gtcgagaact attatggcag aaacgatcat cggccagttc agtaagtgag acaagtatct
    48721 ttaataaata acacatttta ataagtagtt gaacacataa ctaccttact tgcaaaggct
    48781 taacaatatc tatacaggta caacaaaaaa ctgtccacca atttt
//
LOCUS       DAZKCW010000020        47470 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000020 DAZKCW010000000
VERSION     DAZKCW010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.020"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(55..789)
                     /locus_tag="ACG84Z_001192"
     CDS             complement(55..789)
                     /locus_tag="ACG84Z_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFP9162045.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1116..1526
                     /locus_tag="ACG84Z_001193"
     CDS             1116..1526
                     /locus_tag="ACG84Z_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFP9162046.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1519..2220
                     /locus_tag="ACG84Z_001194"
     CDS             1519..2220
                     /locus_tag="ACG84Z_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFP9162047.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2220..3806
                     /locus_tag="ACG84Z_001195"
     CDS             2220..3806
                     /locus_tag="ACG84Z_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162048.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3825..4046
                     /locus_tag="ACG84Z_001196"
     CDS             3825..4046
                     /locus_tag="ACG84Z_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFP9162049.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4043..4804
                     /locus_tag="ACG84Z_001197"
     CDS             4043..4804
                     /locus_tag="ACG84Z_001197"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFP9162050.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5184..5693
                     /locus_tag="ACG84Z_001198"
     CDS             5184..5693
                     /locus_tag="ACG84Z_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFP9162051.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5768..6307)
                     /locus_tag="ACG84Z_001199"
     CDS             complement(5768..6307)
                     /locus_tag="ACG84Z_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFP9162052.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="ACG84Z_001200"
     CDS             complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="ACG84Z_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFP9162053.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7320..8171
                     /locus_tag="ACG84Z_001201"
     CDS             7320..8171
                     /locus_tag="ACG84Z_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFP9162054.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8199..8834
                     /locus_tag="ACG84Z_001202"
     CDS             8199..8834
                     /locus_tag="ACG84Z_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFP9162055.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8854..9627
                     /locus_tag="ACG84Z_001203"
     CDS             8854..9627
                     /locus_tag="ACG84Z_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9162056.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10035..10832
                     /locus_tag="ACG84Z_001204"
     CDS             10035..10832
                     /locus_tag="ACG84Z_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFP9162057.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10810..11223
                     /locus_tag="ACG84Z_001205"
     CDS             10810..11223
                     /locus_tag="ACG84Z_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFP9162058.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11207..13852
                     /gene="mutS"
                     /locus_tag="ACG84Z_001206"
     CDS             11207..13852
                     /gene="mutS"
                     /locus_tag="ACG84Z_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFP9162059.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13870..15978
                     /gene="mutL"
                     /locus_tag="ACG84Z_001207"
     CDS             13870..15978
                     /gene="mutL"
                     /locus_tag="ACG84Z_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFP9162060.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16000..16560
                     /locus_tag="ACG84Z_001208"
     CDS             16000..16560
                     /locus_tag="ACG84Z_001208"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFP9162061.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16645..18633)
                     /gene="treP"
                     /locus_tag="ACG84Z_001209"
     CDS             complement(16645..18633)
                     /gene="treP"
                     /locus_tag="ACG84Z_001209"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFP9162062.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18856..19569
                     /gene="treR"
                     /locus_tag="ACG84Z_001210"
     CDS             18856..19569
                     /gene="treR"
                     /locus_tag="ACG84Z_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFP9162063.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19646..20092
                     /gene="msrB"
                     /locus_tag="ACG84Z_001211"
     CDS             19646..20092
                     /gene="msrB"
                     /locus_tag="ACG84Z_001211"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFP9162064.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20262..20864
                     /gene="ruvA"
                     /locus_tag="ACG84Z_001212"
     CDS             20262..20864
                     /gene="ruvA"
                     /locus_tag="ACG84Z_001212"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFP9162065.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20877..21878
                     /gene="ruvB"
                     /locus_tag="ACG84Z_001213"
     CDS             20877..21878
                     /gene="ruvB"
                     /locus_tag="ACG84Z_001213"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFP9162066.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21907..22485
                     /locus_tag="ACG84Z_001214"
     CDS             21907..22485
                     /locus_tag="ACG84Z_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9162067.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22537..23019
                     /locus_tag="ACG84Z_001215"
     CDS             22537..23019
                     /locus_tag="ACG84Z_001215"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFP9162068.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23136..23510
                     /locus_tag="ACG84Z_001216"
     CDS             23136..23510
                     /locus_tag="ACG84Z_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162069.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24188..25540)
                     /gene="brnQ"
                     /locus_tag="ACG84Z_001217"
     CDS             complement(24188..25540)
                     /gene="brnQ"
                     /locus_tag="ACG84Z_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFP9162070.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25687..26277
                     /locus_tag="ACG84Z_001218"
     CDS             25687..26277
                     /locus_tag="ACG84Z_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFP9162071.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26405..27754)
                     /locus_tag="ACG84Z_001219"
     CDS             complement(26405..27754)
                     /locus_tag="ACG84Z_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9162072.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27922..28662)
                     /locus_tag="ACG84Z_001220"
     CDS             complement(27922..28662)
                     /locus_tag="ACG84Z_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFP9162073.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28675..30267)
                     /locus_tag="ACG84Z_001221"
     CDS             complement(28675..30267)
                     /locus_tag="ACG84Z_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFP9162074.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     regulatory      complement(30405..30579)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(30835..31131)
                     /locus_tag="ACG84Z_001222"
     CDS             complement(30835..31131)
                     /locus_tag="ACG84Z_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162075.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31307..32032
                     /locus_tag="ACG84Z_001223"
     CDS             31307..32032
                     /locus_tag="ACG84Z_001223"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFP9162076.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32025..32867
                     /locus_tag="ACG84Z_001224"
     CDS             32025..32867
                     /locus_tag="ACG84Z_001224"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFP9162077.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32870..33391
                     /locus_tag="ACG84Z_001225"
     CDS             32870..33391
                     /locus_tag="ACG84Z_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFP9162078.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33644..34207)
                     /gene="def"
                     /locus_tag="ACG84Z_001226"
     CDS             complement(33644..34207)
                     /gene="def"
                     /locus_tag="ACG84Z_001226"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFP9162079.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34458..34727
                     /gene="rpsO"
                     /locus_tag="ACG84Z_001227"
     CDS             34458..34727
                     /gene="rpsO"
                     /locus_tag="ACG84Z_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFP9162080.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34915..37041
                     /gene="pnp"
                     /locus_tag="ACG84Z_001228"
     CDS             34915..37041
                     /gene="pnp"
                     /locus_tag="ACG84Z_001228"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFP9162081.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37551..37817
                     /locus_tag="ACG84Z_001229"
     CDS             37551..37817
                     /locus_tag="ACG84Z_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFP9162082.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37961..39952
                     /locus_tag="ACG84Z_001230"
     CDS             37961..39952
                     /locus_tag="ACG84Z_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFP9162083.1"
                     /translation="MATTHNTKKISMTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40306..41607
                     /locus_tag="ACG84Z_001231"
     CDS             40306..41607
                     /locus_tag="ACG84Z_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFP9162084.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41737..43107)
                     /locus_tag="ACG84Z_001232"
     CDS             complement(41737..43107)
                     /locus_tag="ACG84Z_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFP9162085.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVNPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43289..43612)
                     /locus_tag="ACG84Z_001233"
     CDS             complement(43289..43612)
                     /locus_tag="ACG84Z_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFP9162086.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43937..44545)
                     /locus_tag="ACG84Z_001234"
     CDS             complement(43937..44545)
                     /locus_tag="ACG84Z_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFP9162087.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44875..45591
                     /locus_tag="ACG84Z_001235"
     CDS             44875..45591
                     /locus_tag="ACG84Z_001235"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFP9162088.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45604..46299
                     /locus_tag="ACG84Z_001236"
     CDS             45604..46299
                     /locus_tag="ACG84Z_001236"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFP9162089.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46383..47012
                     /gene="udk"
                     /locus_tag="ACG84Z_001237"
     CDS             46383..47012
                     /gene="udk"
                     /locus_tag="ACG84Z_001237"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFP9162090.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15391 a         8788 c         9878 g        13413 t
ORIGIN      
        1 ataaaaaaac ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc
       61 cataaataat aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac
      121 tggtacccat gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg
      181 tacaagacgt ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag
      241 tgaagcaact aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc
      301 ttggaagaat ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa
      361 gaattcattg acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc
      421 taacacatgg tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat
      481 caattgtcca atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca
      541 agggaataga ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct
      601 gattccacca aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag
      661 catccagtca ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt
      721 acctagaacg attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga
      781 gtaatccata aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg
      841 aaaagcatcg gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat
      901 aaaaaaatga attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt
      961 taaaagttct ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt
     1021 tttctcaaaa attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta
     1081 gtaaaatgaa agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca
     1141 ttattatttt cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc
     1201 ctggaagtat cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc
     1261 ctgaaaaaat cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc
     1321 ctgctggtgt aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac
     1381 tgggagcagt cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag
     1441 gtgtagaagc tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg
     1501 aaatggagga gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg
     1561 actttaggag tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg
     1621 aatcctctcg tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc
     1681 tataaagact ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg
     1741 gcacttgcca tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta
     1801 atggctgcga ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac
     1861 ttcttctctc ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct
     1921 atttctgtcg atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt
     1981 gtctctacag gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc
     2041 gaaagtccag ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca
     2101 aaagcaatcg agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac
     2161 ggaatattga ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga
     2221 tgcgaaaacc actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga
     2281 aagacgtgta tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga
     2341 ttctcctcct agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag
     2401 ttgttcagct ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc
     2461 agcagtttag cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact
     2521 tttatgatac gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta
     2581 cgctgaaatt ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat
     2641 ttgcgcaaaa gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac
     2701 agcaactgca aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag
     2761 aagaaatcat tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct
     2821 ggccatttga aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt
     2881 tttttaatgt tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct
     2941 tttttttaag aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga
     3001 tttctgacaa tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt
     3061 attttcaagt agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat
     3121 attatagtga tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac
     3181 cgccctttac agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg
     3241 ggctgccagc agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt
     3301 tcgcctatct ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta
     3361 atcatttagt tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta
     3421 gacacaaaca tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc
     3481 tgactgtgtt taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt
     3541 taatgacaga tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt
     3601 tccgtaatga gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc
     3661 ttctgatttc gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg
     3721 tgactgaaga actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc
     3781 aaaaacaaaa actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa
     3841 ttttaccaga attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac
     3901 tttatgttgt tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat
     3961 tgatcaaaac aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag
     4021 cagatgattg ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt
     4081 atttatcaca ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca
     4141 agatgctttt gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg
     4201 atttcctgaa acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca
     4261 agcggtatcg aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg
     4321 gatattggat gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta
     4381 tgagacgaat gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg
     4441 ccaaaaaagc ggaacgatca tcaatatggc ttcgattgct ggcttgattg ctggtggagg
     4501 tgggatcgct tatacaagcg cgaaacatgc gattgtcgga tttaccaaac aactcgctct
     4561 ggattacgca ggacagggta tccgagtaaa aggaattgct ccaggagcca tccaaacacc
     4621 aatgaatgcg gctgattttg aagggaaagg tgagatggca gagtgggtgg caaatgaaac
     4681 accagtcaag cgatgggcac agccggaaga agtagctgag ctgacgttat ttcttgcctc
     4741 tcctcaagca agctacatac aaggaacgat catcccaatc gacggcggat ggttgttaaa
     4801 ataaccttgt gtttttttca agcttctgta tgataaaact aaagagagaa acaacggttg
     4861 atgataaaaa aagtcgatga ctgttcccga cattcgatgc cgaacagcca gttcaaaaaa
     4921 ttctttttaa taatcgttaa tattcgaaac taagcggctt ttcacgacct cttgatataa
     4981 acgatattca aaagcttgca actgcggtaa caagtccagc caaatgaaaa atataaggag
     5041 ctatttttat ttgaccattc ttattacttg ttgcagggca gctttttcac taccttctgc
     5101 gacacttcag ttggaatttt cttcccatcc tttggtcgcg gtcattacca agataaaatt
     5161 atcttgcaaa ggagaaatag aacatggaaa aaaataatac ccgttcagcc aaacgctgga
     5221 caacgacaga tgtgactcgg atggcgctag tcactggttt atatgtggca gtgacgctgg
     5281 ttttgtctgt ctttagcttt ggagtgattc agattcgtct ctcggagatg ttcaactatc
     5341 tgtccttgta taacaaaaga tacatcgtcg cggtaacagc gggagtagct ttggctaata
     5401 ttgcttctcc tcttggactg atagatgttg cagtaggaag cgtcagcacg ctgcttgtat
     5461 tgcttatcaa ctataaaatc actagtcgca tcaaaaacat gaaaatcaaa atggccgtga
     5521 cagcatgcgt atttgctttt tccatgttta cagtagctgg tcagctaacg attttatatc
     5581 aactaccttt tttcttgaat tggtgggtga ttgctttagg agaattggca tcaatgattg
     5641 tcggtgggat aattatttat tggatcggta aaaaagtgga tttgtcaaaa taaagatctg
     5701 tttaatttaa aatagggcag catggaagag actgaatgtt gagtcttctt ccatgctgct
     5761 tttttgatta atttgtatga agaaatcgat ttagccgttt tttcatcaag ataccgatat
     5821 aagctgctcc agttgccttg attgcttccg gcagtaaaaa cggcagtagt ccactggcaa
     5881 atgcagttgt aaaagtaaga tcaccactta ttttcagcca gatcgttccg cagatcaatg
     5941 cagcaagaga gcccattaga ttggcaaaga ttgcatataa gtaatgagca tccgttcttt
     6001 cgatcatcca accagttatc cacgtttgta agagaaatcc aatcaaatat ccgccagttg
     6061 gcccaaataa aacagctata cctccagtca tccctgaaaa tacaggaaga ccaatcaagc
     6121 caagtaaaag ataaactcca acagatatca atcctagttt tcttccgaga aaagttgctg
     6181 ttaatccaat agcaaatgtt tgccctgtca aaggaaccaa accaaaagga atggtcatct
     6241 gagaaaggac agaaataatc gcggcaaatt ccgcagcaag tatcaattct ttcaatgttc
     6301 ggttcataac gccctctttt cgttaactta atatttttat ttggttaacg aaattgtaaa
     6361 acaaagtgat tactttgtaa atagaaaata taaaaaaaga ccagctatcc aatagatagc
     6421 ggtctttttc aagaaagctt ttgaaattat aagctttggt tgtagtattc aacgacaaga
     6481 gcttcgtcga tttctggata tagttcgtca cgttctggta aacgagtcaa tgaaccttcc
     6541 aatttttcag cgtcaaagct tacgaatgct gggcgtccaa cagttgcttc tacagcttct
     6601 tttactgtta cgatgttttg tgatttttca cgaactgaga tcacttgacc cacttctacg
     6661 tggtatgaag ggatatcaac gcgtttgcca tcaactaaaa tgtgaccatg gttaactaat
     6721 tgacgtgctt gacgacgagt cgttgcaagt cctaaacggt aaacaacatt gtctaaacgt
     6781 tgttctagta agatcatgaa gttaacacca tgtttacctt ctttgatttt gctagctttt
     6841 acgaacaagt tacggaattg acgttcgttc attccgtaca tgtgacgaag tttttgtttt
     6901 tcagttaatt gcatgccgta ttctgattgt ttgccacggc tattaggtcc atgttgacct
     6961 ggtgcgtaag ggcgacgtgc taattctttt cctgtgcctg acaatgagat gcctaagcga
     7021 cgagaaattt tccatgatgg tcctgtataa cgagacatta aaatttcctc caatgaatat
     7081 aagtttttgg agtaaaataa tccgttgaaa aattcataat catatagttt gttcttcaat
     7141 cttcaccttt gcagccgcgg ttacacaatc gaacccgaga cggggcaaca aactagggat
     7201 gagttattat ttttctgctg cattatttta cacaaattac agtatatgat agatcatcca
     7261 cgaatgtcaa gataattagt acataaaaac gctttacaaa cctaggctgt ctttataaaa
     7321 tgagagggta tgtgcaaatg gaaaaaagcg aaggaagttt aaggagaaaa tcaatgaatc
     7381 cggtatcacc attatttgag aaaatcgatg cttcaattga aaagaaggcg aatctttttg
     7441 aaaacagctt ttcacgttac gctgttcgag cggttctcgc ctgtttgttt ttgactttag
     7501 gaacggctgt ggcatttgcg atcgcgatga agggggaaga tatcgcgcat ggtctaggaa
     7561 agattttata cgcatttatg ttcagctggg gtctggtcat gattctatac atgaacgccg
     7621 aattaggaac atcgaatatg ctttatatga ccgtgggtgt ttttcggcag agacttgctt
     7681 taagtaaggc agccaagatt ctatttgcct gtattttttt caatatgatt ggcggtatat
     7741 tatgtggatt tctaatttct atgactacgc catttcaaga tttaacgttg gacaacttta
     7801 tgttagaatc aatagcagta aaactagcaa aaccttcagc aacgattttg gtggaaggga
     7861 tgtttgcgaa tatcgttgtc aataccgctg tactgatcag catgcggatg aaagaggatg
     7921 tcggaaaagt gatcacagtc gtattcatca ttttcatttt tgctttttta ggatatgaac
     7981 acgtgatagc gaattttcct gcctttacgc ttacttactt tgcttctcac ggacagatgg
     8041 atggaatgac agtcagcaat gtgttacata atttgttttt tgctttggca ggaaattata
     8101 ttggtggcgg tttagtaatg ggactgggat atgcttggct gaatcagtca aaatcatcct
     8161 atgtggacta aaaagtcgtt cattaaaggg gaagtgccat ggaagtttta gtttttccaa
     8221 aaaatgagga aaaagcgtta caaatggaaa agtacatgaa aaatcttttt tcctttgctg
     8281 gagtacctaa gccggaacgc gctcttttac aacaaccgtt actggatgag agcaaaaatt
     8341 tatctatttc tgaagtttta gcttttgttc attattatta tgaacaaatc gaaagagagt
     8401 atcagtatgt agcgatcgat ttagtccaga aaaacatcaa acggcttaca tttgaagact
     8461 tagtcgtatt gttgccacta gttcagaaaa aagaatggtg ggacagcatc gactcttgga
     8521 gaaaagtata cagcacatgg tgtaaagcct acccagagca gcgtgaagaa gtctttcaat
     8581 tgtttgaaaa aaaggaagat ttttggctac gtcgaatagc aatcacgttg caattaggtt
     8641 ataaacagca aacagacaca ggactattga tccgagcaat agacgaagat cgtcaaacaa
     8701 aggaattctt tatccaaaaa gcaattggtt gggcattacg cgattatagt aagaccgatg
     8761 ccgattgggt aaaaagacag ctgacaacag atttgagtaa gttagctgtt cgagaggcaa
     8821 gtaagtattt ataagaaagc gagacgacaa gagatgagac gcaaattatt tgcttttgat
     8881 attgatggaa cgttgttaga ttcaaacaaa caagctttag atagcacaag agaagcattg
     8941 gaaaaattac gcaaagccgg tcatctggtc acgattgcta cagggcggag ccgatttcat
     9001 gcgcaagaga tcattcgcga tcttgatttt acgaactaca ttttatgtaa tggagcggcc
     9061 ggttttttag accatgaaca agtatataag aatttactag atcgcgacca gttggatgcg
     9121 ttcgttcaag aagcgcatca tgagcagatc gatacagctt ttgtcagctt agacaatatc
     9181 aagcgttctt cttccaatga tgtaacggtg atggaagaag cgatgcattc tttcggtgct
     9241 gtcttgcctg aattagatca gttttttgca gaggaacaag aaatatacca agcgttagca
     9301 tttttcgatc aaacatatga tgggaagttc tcttcatatg ataaaattcg atttgtccgc
     9361 tggcatgaga acagtgtaga tgtcgtacct aaaaatggtt ctaaagcagc gacaattctg
     9421 cacttagcag aacaagtagg catccctcat gaagacatca tcagctttgg cgatggacaa
     9481 aacgaccgtg aaatgttgcg catgtcagga attgggatag ctatggggaa tgctgtgcca
     9541 gaagtacaag cagaagctaa gatggtcact gatacaaacg atcaggatgg aatttggaag
     9601 gcattgaaag agttaagcgt gatttaaaag aggttgtgaa aaagctgttc tgcatcaagt
     9661 aataagccca gccaaacaaa aatagctcct cctatttttc gtttttctgg gcttattacc
     9721 gcagatgcaa gctttcgaac accgtttaag gaagaggtcg tgacagaagt ggtcagtttc
     9781 aagaaataag aagggattta cgaaaattgc ttctcaaatt tttgtaaaat tacggcttat
     9841 ttctgaagaa gtagatgaaa caacgtttat tcgggaaatg ggactgtgac aagatgtttg
     9901 tcatagtccc atttttttat tttatttttc aaaactaaga aataccagga aagagttcct
     9961 tttgtttgac cttttctttc ttattgaaaa caactataat atagagtgat gttaaaagag
    10021 aagaggaatt tagtgtgcgg gtattgttta ttggtgatgt agtaggttca atgggacgag
    10081 agatgattac tgaatatctt cctagattga agaagaagta ccgtccgcaa gtaacgattg
    10141 taaatggtga gaatgccgct tctggacgtg gaatcacaga aaaaatctat aaaaaatttt
    10201 tgcaagacgg cgtagatgtc gtgacgatgg ggaatcatac gtgggacaac cgcggaatct
    10261 ttgagtttgt aaatgaagct aaaaagatgg ttcgtccggc aaattttccg gaagggacgc
    10321 ctggacaagg gatggtcttt gtcaaagtga accaagtcga actggcagtg atcaacatgc
    10381 aggctcgttc ttttatggtg gacttggatg atccttttcg taaaatgaat gagctggtag
    10441 aagaagccag aaaacgtacg ccgatcattt ttgtagattt tcatggagaa acaacaagtg
    10501 aaaaacaagc aatgggctgg tttttagatg ggaaagtttc agcagtggtc ggtacacata
    10561 cacacgttca gacaaatgat gcgcgaattt tgccaagagg aacagcgtat ctgacagacg
    10621 ttgggatgac aggtccctat gatggtattt tgggtatgcg cagagaacct gtaatcgaaa
    10681 agtttctgac tgcattacca aaacgttttg aagttgtgga acaaggccga tcgattttaa
    10741 gcggctgtat cttggaattg gatgatacga caggtcatgc aaaagaaatc cagctgattc
    10801 agatcaacga tgatcgaccg ttcatggagt agaaagagag gcagtttttt gcagcaggag
    10861 ccggaaattc aaaaagaagt aaggaaactg acaaaacttt taagagagaa tgaaacgatc
    10921 attcgctaca aagaacttga agaaaagatc cagcaaaacc agtatttagc tgagttgaga
    10981 gaaaaaatca aacaagcgca aaaagatgct gttcattttg cccactatga caaaccagca
    11041 gcagaaaaag aagcaatcaa acaagcggat caattcatgc aagaatttga tcagcatccg
    11101 cttgttgtag cttatagaaa acagctgttg gaagcagatg atctgcttca tcatttaaca
    11161 actatgatac aagaagaaat caatggacaa atagaggagg aaaaacatgc ctcaaaaaac
    11221 taaaaatact cctatgatgg aacaatatct aagcatcaag gcccaatacc aagatgcttt
    11281 tttgttctat cgtttaggag acttttatga actattttac gaagatgcga tcaaagcgtc
    11341 acagcttttg gaattaacgt tgacgagcag aaatcgaaat gcagaagaac ctattcctat
    11401 gtgcggtgta cctcaccatg cagcacaagg atatatcgat gccttgattg aaaaaggcta
    11461 taaagtagcg atttgcgagc aggtagaaga tccaaagacg actaaaggga tggtcaagcg
    11521 cgaagtgatc cagctagtca ctcctggtac agtcatggac agcaaaggat tgtcggcaaa
    11581 agacaacaat tttttaacag ctgtagttag tcaaggaaat gaatttggct ttgcttatgc
    11641 cgatttaagt acgggagaat tgaagacggc tcggttgcat gatgaagaag ctgttttaaa
    11701 tgaagcctct gcattgcaga caaaagaact cgtattaggc agtgagatca ctgataccct
    11761 tcgtgaacag ctaagcgggc gtttagggct agtcttttct caacaaaatg agatggaaga
    11821 aaacgcggaa tttagctttt tgacaagcga actagtcgat ccgctggaaa aagaagcaac
    11881 cggcaaacta ttgacttatt tatcggtgac acaaaagcgg agtttagctc atatccaaaa
    11941 agcagtagaa taccaaccag atcatttttt gaaaatggat tattattcaa aattcaacct
    12001 agaattaagc caatctattc ggactgggaa aaagcacggc actcttctat ggttgttaga
    12061 tgaaacaaaa acagcaatgg gtggccgttt actaaaacaa tggctagacc gtccgcttat
    12121 ccaggcaaaa caaattaaag caagacaaga aatggtcgct tctttgctag acagctattt
    12181 tgaacgtatc gatttgcagt cagcattaac gaaagtctat gatctggaac gcctagcagg
    12241 tcgagtagct ttcggtaatg tcaatgggcg agacttgatc cagctgaaaa cttctttaga
    12301 acaagtgcca atgatcagag ggttgattga aggaatcgat caaggtcaat ggcaaagtct
    12361 gctttcagaa atgcagccga tggaccatct cgtccaattg atcgaccaag ctatccaaga
    12421 tgatccgccg ttacaaataa cggaaggaaa catcatcaaa gatggattca atgagcagct
    12481 cgatatgtac cgttctgcta tgagaaacgg aaagaaatgg ttggcagaac ttgaagcaaa
    12541 agagcgtcaa gaaacaggaa tcaagaactt aaaaatcgga tttaaccgcg ttttcggtta
    12601 ttatatagaa attacaaaag caaatcttgg aaatgcagaa ctggagaagt atgaacgaaa
    12661 acaaacttta gcaaatgcag agcgtttcat cacaccagaa ctaaaagaat tggagacaca
    12721 aatcctcgaa gcagaagaaa aatctgttga tttagaatat cagttgtttt tagctgtgag
    12781 agaagaagtc aaaaaggcta tccagccgct acaagtactt gcaaaagcaa tcagtgcagt
    12841 agatgtgcta caaagttttg caacgatcag cgaacgctat cagtatgttc ggccagaact
    12901 tgtcagtgac aagcatcagc ttctgatcaa agacggacga catcctgtag tagaaaaagt
    12961 attaggacat caggaatata tccctaacag cgtagaaatg gcagaagacg aaatgatctt
    13021 gctgattaca ggaccgaata tgtctggtaa aagtacgtat atgcgacagt tggcattaac
    13081 tgttctgatg gcgcaaatgg gctgtttcgt tccggcaaaa caagcagttt tacctatttt
    13141 tgatcggatt tttacccgaa ttggtgcaag tgacgactta attgctggac aaagtacttt
    13201 tatggtagag atgatggaag ccaatcaagc cctgcgttat gctacgccaa acagtttgat
    13261 tttgtttgac gaactagggc gaggaacagc aacctatgac ggaatggcgt tggcccaagc
    13321 aatcatcgaa tatatccatc gtcatgtaca agcaaaaaca ctcttttcta ctcattatca
    13381 tgaactgacg gtacttgaga aagaacttcc gcagcttaaa aatgtccatg ttggagccgt
    13441 tgaaaaagac ggagaagttg tcttcttgca taaaatgatg gatggacctg cggataaaag
    13501 ctacggcata catgtggcaa agatcgcagg attgccttcc aatctactag aacgagcagc
    13561 agatatcctg catacgctag aaaatggcga taacggacac catactgttc cagctgaagt
    13621 agaagagaaa actaaaacag ccaaacagga gcaaataaaa ccacctgcag aaaaagtaaa
    13681 tcaagaccat atacaagacc gtgtaaaaga agaaaaccaa cagctttctt tattcagtga
    13741 attatccgaa aatgaaacag aagtcattga atcactgaag caaataaatt tactagaaat
    13801 gacgccaatg gatgcactaa acacattata tgaattacaa aaacaactgt aggaagaagg
    13861 cggatatcga tggccaaaat ccaagaatta tctgaacgtt tagctaatca gatcgctgcg
    13921 ggagaagtag tggagcgacc agcttccgtt gtgaaagaat tagtggaaaa tgcaattgac
    13981 gccggcagta ctcagattga tatcttagtt gaagaagcgg gactgcggac gatccaagtg
    14041 attgataacg gagaaggcat tttggcagac gacgtagaga atgccttcaa gcggcatgcg
    14101 acaagtaaga tccataatcg cgacgatctt tttcgcatac gaacgctggg ctttcgaggg
    14161 gaagctttgc caagtattgc ctctgtttct gaaatgactc tggaaacggc gaatcaggaa
    14221 gaaaaacaag gcacctatct gtcgctgaaa ggcggagaag ttattgagca tcgaccagca
    14281 ccactgcgtc aaggaacgaa gattaccgtc agcaatctgt ttttcaatac gccagcccgc
    14341 ttgaaatacg tgaaaacact gcacacagaa ttagcgaaca tcggggacat cgtcaatcga
    14401 ctggcattga gtcatccatc gattgctttt cgtttagtac atgatggaaa caaaatgctg
    14461 gcaactgctg gaaatggcga tctgaaacaa acaattgcgg gaatctacgg attatctacc
    14521 gcaaaaaaaa tgctgaaaat cgaaggaaaa gatctagatt ttgagttatt tggctatgtt
    14581 tcattgcctg aggtgactcg tgccagtagg aattacttat cgacgatcat caatggacgt
    14641 tttatcaaga acttttcctt gaataaagca atcgttgcag gttatgggtc aaaattaatg
    14701 gtcggtcgtt tccctattgc tgtattggaa atcaaaatgg acccgctttt agtagatgta
    14761 aatgttcatc cgacgaagca ggaagtccgg ctgtcgaagg aaaaagaact aacagagcta
    14821 attagtaacg ccattcaaaa agcattgtct caagaaaatc tgattccaag tgcagcggat
    14881 aatctacggt ttaagaaaaa agtacctgat cagcctaaaa cagaacaaat cgaaatcgat
    14941 ttgtcctacg cttttgaaga agaaaaacct aaaaagccaa gtagtttgaa ttttgatcga
    15001 gagacaggta cctttttcgt agaagaacta aagaacacat ttgttgacag aattgttgat
    15061 aagtctgtgg aaaatgttga aaactattct ggtttttctg aagaaaacac cacttatcca
    15121 gaaaaaacag cgaaaacggt ggataagttt ggtgaaaatg ttgataactt tgtagaaaaa
    15181 acagtggaaa aatctgaaaa gaaagaattt cccattgtgg ataacatgga gaaaacaaat
    15241 gaagaacaag cagataaatc cgtagaagag gatgaaaaga tttacgagga agaattgaca
    15301 ctccatcctg aatttgattt cactcaagga aacgacaaaa cattagaaca agccatcaag
    15361 aaattagaaa cggaaaaacc agtacaacgt tttcctcagt tggaatattt tggacagatg
    15421 cacggaacgt atctttttgc ccaaagtagc gatgggttgt acatcattga tcagcatgct
    15481 gcccaagagc gcattaagta tgaatatttc cgggaaaaaa ttggggaagt atctgatgat
    15541 ctgcaagaat tgcttgttcc atttgtgtta gactatccaa acagtgatgc tttgaaatta
    15601 aaagagcaaa aacacttgct agaagatgca gggatttatt tagaagaatt tggtcaaaac
    15661 agctttattg tacgggccca tcctacttgg tatcccaatg gagaagaaga atcgattatt
    15721 cgggagatga tcgatatgct gctgacaact ggaagtgtga gtgtaaaaaa attccgtgaa
    15781 gcaacagcaa tcatgatgag ttgcaaacga tcgattaaag ccaaccatta tttgaatgaa
    15841 gcacaagcac gtgtgctgct gaaggatctg gcacgatgcg aaaatccttt caattgtccc
    15901 catggccgtc cagtattgat tcactttacc aattcggata tggaaaggat gttcaaacga
    15961 atccaagacc cgcattaagt caaagagaag agggaaaaca tgaagattgt attagcatcc
    16021 caatcaccaa gaagaaaaga gttattggct catatcgttt cagaattcga gattgaacct
    16081 gctgatatcg atgaaacgcc atttccagac gaacagcccg tcgattatgt tcgtagaatg
    16141 gctgaagaaa aagcacgaac tgtctgggaa caagatgaaa aagaagacca tttagtgatt
    16201 gccagtgaca cgactgttgt tctcaatcaa gagatcatgg gtaaaccaga agatctggct
    16261 gaggctgaat tcatgctgaa aaaactaagc ggggaaacac atactgtata tacagctgtt
    16321 gttttaaaaa caaaggaacg agaagaacgg atactagcag aagcacatgt cactttttat
    16381 cctttgacag acgaagagat caaacgctac ttggagacgg gggattatgc ggataaggca
    16441 ggggcatacg gcatccaaaa tgctgcgagt gtattcgtca aagaaatttc tggagattat
    16501 tacagtatcg taggatttcc gattggtgct gtcaatcagg cactgaaaac attcatttaa
    16561 acaaaaaagc ggactatctg attttcgatt gaaaatccat gatagcccgt tttttttatt
    16621 gaaaagatta cttatctact ctgactaaga ttttacttca gctttaccga ctgcttcgcc
    16681 cgggcgaaca agtcctgatt ggtcaagaga aagtcctgca actttttcat tattggtcaa
    16741 agcaacaata atgtcagttt tcttgccagc ttgttctatt tctggcaaat ccatttcagc
    16801 aatcagggtc tctggtgtga caaggtatcc ttctttcacg aatacattga aaggaacacc
    16861 ctttagttca acagtatcta atcccatgtg aacaagtact tccagcccct cattagaaag
    16921 aataccaatg gcatgttttg tttcaaagac actcgtcact ttaccgttta ctggtgcata
    16981 gactttgccg tttgacggtt cgacagcata accgtcaccc atcatttttt gtgagaaaac
    17041 tgggtcattt acttcagtta tttccttgat ggtccctgca gcgactgcga ataatgtttc
    17101 ttttgttgca actgccgtac cagttgctga aacaggttcg aaagactgtg gcgttgctgt
    17161 tgcgccattt gctgtttgaa gttgtacatc agcagcattt tcaggaacag caggatcaat
    17221 cttattcaaa attccctgac gtctaaagat gatcgtcaag ccaaatggaa tgatgacagc
    17281 aatgatcatt gcgatgatga aaggtaccca tgtttctgct tggatagcta gtattcctgg
    17341 caaaccgcct actccgatcg cgttagctcg aacacccatc aagttagcaa acatgccagc
    17401 taatccagag ccgaccattg cagcgacgaa aggatagacg tatttcaaat tgattccgaa
    17461 catagcaggt tcagttacgc ctaagtaaca agaaatcatt gctggaatcg agatttgttc
    17521 ttctttttta ttcccacgat gtaagaagat gatggctaag actgcagagc cttgggcgat
    17581 atttgataaa gcaatcatcg gccataaatt cgttgatccg aaatctgcaa tcagctgcat
    17641 atcgatggca ttggtcatat ggtggagacc agtaatcact aaaggagcat acaggaatcc
    17701 gaatacggca ctaaacaacc agctgataga agacgtcaat ccagtattta cgatatttga
    17761 gatccagctt ccgactgtcc agccgatagg acctaaaata acgtgtgcag ctaaaacagt
    17821 tggtaacaat gaaaacaatg gaacaaaaat catcgagatc gactgaggga tatatttgcg
    17881 gaagaagatt tctagatacg ctaacataaa ccctgccagc atggctggaa taacttgcgc
    17941 ttgataacca atcatctgga cttgagcaaa accaaaatcc caaaatggaa tatctgctgc
    18001 ggctgtggaa gctacactat aagcatttaa taattgcgga gaaactaacg taattcctaa
    18061 aacgattcct aatatttgtg tagtacccat cttttttgca atactccaag tgatacctac
    18121 tggaagaaaa tggaaaattg cttcaccggg taaccacaaa aaggcattga caccattcca
    18181 aaacttcgag tgttcaacga ttgttccacc aagactttca aactggatac cttcaagtac
    18241 atttctgaat ccaaggatca atccaccgac aatgattgca ggaatcagtg gtgtaaagat
    18301 ttctgctaaa acggcaatag cacgttgaac gggatgaagg ttttgttttg cagctgcttt
    18361 tccttgttct ttggaaaccc cttcaactcc agatactgca acgaagtcgt tataaaaagt
    18421 agaaacatcg tttcctatga tgacttggaa ctgtcctgca ttcgtgaaca tcccttttac
    18481 gctaggtata tcttcgatcg ctttttcgtc cgcttttcct ggatcattca ggacaaaacg
    18541 catacgagtc gcacaatgac taactgcagc aatattttct tttccgccga tatcatgtaa
    18601 cagcttctcg gcatctgctt gatattttgc catatcaata aacccctttc tcttaacttg
    18661 tctatgcaag ttgtttcttc atttactata ctttttttcg gagagaattg caagcgtttt
    18721 attaaaaagt acgagagaaa atgatatcgt tttaaaaagc ttaaaataag cttttcttaa
    18781 aaataggaac attgaaatac aaaaagagct gtagtatagt gaagaaatga tggaagaacg
    18841 agtgagggaa aaaacatgaa taagttcaat gaaatttttt tagatttgga acagaaaatt
    18901 ttagcgaaag aatatcctcc gcattcgctt ttacccagtg agaaccaatt gatcaaaatt
    18961 tatggtgttt cacgagaaac aattagaaaa gcgctgaatc ttttgactac ggaaggttat
    19021 attcaaaaaa aacaaggaaa aggttcgatc gtactggatc ggaatcgctt cgactttcct
    19081 atttctggat tgactagcta taaagagcta caggagaccc aacgtattcc aagtgaaacg
    19141 atcatccata cgttagaaga aacagaagtg acaaaagcat tgaacgagat cactggctgg
    19201 gagatcggtg cgcctgtttg gcatttgata cgcgaaagaa aaatcaatgg cgaagtagtt
    19261 atattagaca ccgattatct attaaaggaa atcgttccta ttttaactcc agcacaagca
    19321 caaggatcga tctatgaata ttttgaaaat gagctttctt tgacgattgc ttacgcgcaa
    19381 aaggagatca cagtagaaga agtaacggaa atcatgaaaa cagcgatgga tcttcacgat
    19441 gacacttatg cagtagtagt cagaagcctc gttcatctgg aagatacccg ctgtttcgag
    19501 tattctgagt cggttcaccg attagataaa ttccgtttcg ttgagtttgc ccgacgccga
    19561 aaagtgtaaa tagttcaaaa gaaagcaaat tgttggcatc tgtccacttt ggcgctatga
    19621 taggatcaca aagggggcat ttttaatgga taaaccaata agaccagaaa aagaagaact
    19681 gaaagaaaag ttatcaccca tggcttatgc agtcacacaa gaaaatgcaa cagaacgacc
    19741 atttagcggg aaatatgatg atttttacga aaaggggatc tatgtagata tcgtcagcgg
    19801 tgaaccgtta ttcagctctg cagaaaaata tgatgcaggt tgtggctggc catcattcag
    19861 caaaccaata acgaaaagac aagtgcgcga aaaagccgat ttttctcatg gcatgcatcg
    19921 aatagaagtt cgaagcaaag aagcagattc tcatctcgga catgtgttta ccgatggacc
    19981 agtagatcaa ggtggtctac gttactgcat caattctgcc tcactgaaat tcattccata
    20041 tgaaaagatg gatgaattag gttatgggga attcaaatca cttgtagaat aatggaaata
    20101 cacaaagagc ggtacaatac ggggatttac tcgatcgtcc gctctttttt tattcaagcg
    20161 attgctattt gaaagaaacg ctccctagac tccttttttc acaaggtgaa atgtgctaca
    20221 ataaagggaa cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag
    20281 gtgtggttac ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc
    20341 agatcgcact aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt
    20401 atgtccatca ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag
    20461 aaaagcaact gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg
    20521 caatcatggc aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca
    20581 cttatttgac gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc
    20641 taaaaggaaa attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa
    20701 acacaaaaga cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca
    20761 gtgatcgaga aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg
    20821 atgagtatct acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga
    20881 cagatgaata cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc
    20941 ttcgaccaca gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga
    21001 tttacatcga agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc
    21061 ctcctggatt aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata
    21121 ttcgtacgac gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg
    21181 aactggaagc aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag
    21241 aagagatgct ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc
    21301 caaccgcaca tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac
    21361 gggcaggtat gctttctgca cctttacgag atcgatttgg catcatttct catatggaat
    21421 attatgacga acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag
    21481 agatcattga agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg
    21541 ctaatcgctt gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg
    21601 atcgtcctat agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt
    21661 atgttgacca gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt
    21721 taagtacgct ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac
    21781 cgtatctgat ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt
    21841 atgcctatga acattttggt tacgactatc atatatgatt tttgctttta gattggagga
    21901 aaatgaatga gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg
    21961 tgccaaacgc aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc
    22021 aatcgacaaa cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat
    22081 tgtgaggatg cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag
    22141 caagcattga aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg
    22201 ctttctgacc cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc
    22261 aagatttttg aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat
    22321 gctcgttttt tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat
    22381 gaagaaacac cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta
    22441 tattcttatc gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg
    22501 ttggaaaagc aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt
    22561 ttgggaaata tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta
    22621 gaaggaaggg aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga
    22681 aagacaccgc accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat
    22741 atggttgctc ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg
    22801 gatcaagaaa atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc
    22861 catttgtttt taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat
    22921 accaataact ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat
    22981 atttggattg atgaaaataa aataacaaac aatttgtaaa gttaacgctt tctttttaag
    23041 gcgatgttag agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa
    23101 gtaacacttt cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa
    23161 tgaagaagct tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa
    23221 atgacactga agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc
    23281 aaaaagctgc tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta
    23341 gcaagtatga aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga
    23401 tgatccgcct acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa
    23461 aaataacaat cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag
    23521 atagaaaagc acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc
    23581 tttaagctga tatcagtaaa acggaacgtt ttaggatgag tatcacagca tgacagcatt
    23641 gggttgatta gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct
    23701 agccggggag ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt
    23761 tggtatgctt atataatagt cactagttgt gaatattttg tgacgaaagt tttcgaaagt
    23821 tgttaagttt ttttgcgaaa actattttta tatcatatat atgtctaaaa tctatattat
    23881 aaaagaaatg ttgtttgatc agcttctctt cggtattagt tcaaaacaaa acggcaaagt
    23941 atatggagct actttgccgt tttgtttctc taatactcag gtcagtttat agacgctcaa
    24001 taaacggtgt tcaaaagcca gtttctcggt attaagtcaa atttatgcaa aaatgtgaga
    24061 agccattttc aaaaaatatt tcttaatact cgaaactgag cggctttttc acgacctctc
    24121 aataaacagt gttcaagaga cagcctatcg gcaataaggc tgaacgtctc tttcacaacc
    24181 tcttttatca atctgctact tcttctttct tagcgaaact ccaaatcagt ccgataacaa
    24241 aaccgataac tgctggtacg atccacccca tccccaattt gaaaaacggc aagtagcttt
    24301 ccgcaacata taaaagattt tgaacaatag gtgtttgttt gatagtttct gggcaagcgt
    24361 tcaacccatc aaaaatcgaa gcaatcaatg taaaataagt agtcattcga taaacagccg
    24421 tacgctgctt aaacaaagga ccaactaaca ctagtaaaat cagtgtcatt gctaatggat
    24481 agatgaacat caaaacaggc aacgaaaatt gaatgatatt cgtcaagcct acgtttgccg
    24541 ctaaacaagg aaggatacta gcaagtgcaa caaagaatgc gtaatttctt tgcggaaaca
    24601 aatctgtgaa tgtttctgca aaagctgtaa tcaaaccaat accggtcttc aagcaagcta
    24661 atataacgat aaatgctaat aagatactgc cataagtacc taaataatga tcagcaatct
    24721 gagccagcgt gatcccgcca ttttcactta gagcaaagct acctaagctc atagcaccta
    24781 aataagcgag caaagtataa atgattccca tcaatataat gctgatcgca ccagatttga
    24841 tcgtgtcttt agcgatttca gcaggttttg ttacacccat gttttggatt gttgtgacaa
    24901 tgatgatccc aaatgctaaa gcagcaagcg catctaatgt gttatatcct tgagtaaacc
    24961 ctgtgaaaaa agcatgctct tgataatttg gctgaatagg cgcttgattt acagaaccta
    25021 gtggattcaa aaaagcaagg agaagcaaag cacctaataa aaccaaaaat gcaggattca
    25081 ggaactttcc aacataatct aatatctttg tcggttttct tgaaaaccac caagccagca
    25141 caaaaaatac aatactgaaa attgctagat atagcgtctg tctgctagga tcgataaatg
    25201 gtgctaaacc aatctcgaaa gatgtggttg caaggcgagg taaagcaaaa aacggtccga
    25261 taactaagta aagcaagatg gtaaaaacca tcgcatatgt ttgatttatc cgttttgcta
    25321 attcatatac acctgagctt ttcgatacac caatggcaat cacccctaag aagggaagac
    25381 cgataccggt aaccaagaaa cctagattcg cccaaaaggt agcagcgcct gcttcttgac
    25441 ccaaatgaac gggaaagata agatttccag caccaaaaaa tagaccgaaa agcatggagc
    25501 ctataaaaag atagtcttta aatgataatt tttttgtcat acataactcc tttacggttt
    25561 ttttaaaagt aacaaaattt cgaaaaatat gcaacaattt tcagaaaatt tcctatataa
    25621 aacgacggtt atttaataac gtaagtgata aaataaaagc gctgaatcat ctgaggagga
    25681 atcatcgtga caaagtcgag attagaagca tttactgatg gagtggtagc cattgttttg
    25741 agagttcttg tattagagat caagatccct aatacatcta gctttcattc tttatgggtc
    25801 atccgaaata cattattagc ttataccatc agctttatat ttgttgcggt gatctgggtg
    25861 aaccatcatc gtatatttca gatggcagaa cgaattaatt accgagtggt ctggtcgaat
    25921 atctttttgc tcttttggct gactttatgt ccttctgtta ctagttgggt cgggcgtaac
    25981 cctgaagctt tttggcctga gatggcttat gtcttagtat acacgatgtg gagtttttct
    26041 tttggtatct tgatgaggca aatcatgaaa gcaaataaac cagattccca tgtcgtgaga
    26101 gttttgtcaa aggaccgtcg aagtcttatc tccatgatga ttaacttatg cttgattgcc
    26161 ggtgtctttt ttgtaccgtt gatcgggtta ttcggacgtt tttttgtatc tggtatttgg
    26221 attttttcct ataaaaaagc agatgcctat tatcagcggt tgtttccggg gaaatagaaa
    26281 agaggctggg acagaagctt ttaactccaa gaaataagcc gaaatttcac aaaaatttaa
    26341 gaagcaattt tcgtaaattc cttcttattt ctcgaagctg accacttctg tcacaactac
    26401 tttcttactt cttacgttca tatttcatat gatagattag taatagaagc aagaaccaca
    26461 caggtgttag taataaagcg attctcgtat cttttcctag gaacaagacg acacacacaa
    26521 aggccatgta aagaaatacc agataattac taaatgggta caacggcatt ttaaatgaat
    26581 gagctttttt gccgaggata cttttacgat atttcatgtg cgtgtagaca agcatactcc
    26641 agataaacaa gaaacaagta gtggcaatac tgcttactag tgtgaatact tcactaggca
    26701 tcacgtaatt caagataaca gaaatgaaaa tgacgatagt agaaaatgtc aaagcattcc
    26761 ctggcacatg atgtgttgtt aactttttga attttttagg ggcactgcct tcttgcgcta
    26821 aagaacgaag catacgtcct gtactatata ttgcactgtt gcaggcagaa gctgctgcac
    26881 ttaatacgac taaattgatc aaggaagcag caatcgtgat cccaatttcc gaaaatactt
    26941 ctacaaatgg actgttatct ggattcaagc tgttccatgg atagattgcc ataatgacaa
    27001 aaagagatcc taagtaaaat aagatgatcc tgataggaat attattgata gcttccggca
    27061 acactttttc aggattttct gtttctccag cgactaatcc aactaattct atcccagcaa
    27121 aagcaaaggt taccatttgg aaagctaaga taaatccttt tgcaccagtt ggaaagaatc
    27181 cgccatgaga ccatagattc gtgatactgg ctgtgccaat atctgtcgta tagtgggtga
    27241 ggatcatata agctcctacg aggataaagg caatgatcgc tacaactttg atcaatgcaa
    27301 accaaaactc taactcacca aacaatgaga cagccaccat attcaagcaa agaagaagac
    27361 ctaatgcaat cagttcagga agccactgag gaacaccagg cgcccagtag cgtacataca
    27421 ttccgatggc tgttaaatcg gccattgcaa tcgataccca gcagaaccaa tacgtccagc
    27481 cagtgatgaa agccgctttt ttgccaagat attctgcaac aaaatccaga aaagaatggt
    27541 tattggtgtt tgataacaga agttcgccta acgcacgcat aatgaaaaaa cagatgcatc
    27601 cagtaataag ataggcgagc aatatcgaag ggccagctag ctggatagac tttccggaac
    27661 ctaaaaacaa ccccgttcca atcgctccgc caatagaaat cagttggaca tgtctatttt
    27721 tcagtccacg ctgcagttct tgctcttcat tcatttttaa atcatcctaa ctaaaaaagt
    27781 ttaattactt ccatattaaa agagttttct gaaaaacaca actaagattc caaaattttc
    27841 agaaatttac cttttatgag taattcataa aaaagaactg cggtaaacac cgcagctctt
    27901 tgtcccaatc agctattgat cctaagcatt taaaatacgt gaaaggaatt cttttgtacg
    27961 ttcttctttc ggatggacaa agatatcttc tggtgtacct tcttctgcaa tcacaccttt
    28021 atccataaaa atgacacggt cagatacatc ttttgcaaat tccatctcat gcgtcacgat
    28081 aagcattgtc aagccagtat gtgctaagtc tttgatcgta ttaagcactt cgccaaccat
    28141 ttcagggtct aacgccgaag taggttcgtc gaatagcaat acatctggat tcattgataa
    28201 tgcccgagca attgcgacac gctgtttctg tccaccagat aattgtgctg gtttggcttc
    28261 gatataacga tccataccaa ctttttccag attttcgatt gctacttttt tggcagtttc
    28321 tttatctcgt ttcaggacag ttgtttgacc agacatacag ttttccaaga cattcatatt
    28381 gttgaacagg ttgaaggatt ggaaaaccat acctagattc gttcgatatt taggtaaatt
    28441 atatttagga gctaatacat tttctccatt ataaatgatc tcgccgcctg ttggtttttc
    28501 cagtaaattg atacagcgca agaaagtaga tttaccagaa ccggaagaac cgatgatcgt
    28561 cacaacttca cctttattga ctgttacgct gatatctttc aatacttcat tttcaccgaa
    28621 gctttttctt agatgtttga tttcaataat tttttcattc atgattcttc ctccttattc
    28681 ctgcaaattt gaattgtcga tttcttcaag cttggtataa gctgaaggac catcgatttt
    28741 cttttctacc gcccgcagga ttctggtgat cgtaaaggtc atgactaagt agatgatccc
    28801 gacgatcgta aatgtttgga agaattggaa attcgcaccg gaagcagagt ttccttggaa
    28861 gaacaaatca gctacgccga ttacacttaa aactgctgta tctttgatat tgataacaaa
    28921 ctcatttcct gttgctggca agatattccg taaaacttgt ggaataacaa cttttctcat
    28981 cgtttggcca tgggtcatac caatggcttg cgcagcttcg aactgccctt catctactgc
    29041 aaaaatcccc ccacgaacga tctctgtcat gtaagctcca gtattgagag agacaataaa
    29101 caaagcggca atcgttcggt tcaatgaaat gccaaaagcg agtgccagac cgtagaagat
    29161 gaccattgct tgtaccatca tcggtgttcc gcggaatact tcgacataga tagaaagaag
    29221 tgcatttccg attttttgga agaagcgagt cagtgcattt cctgattcag gtaccgaacg
    29281 gaagacacca atcagtaatc caagtgtagt accgacaact gtcccgatca atgcgatgaa
    29341 caaggtaagt ccagcacctc gtaagaacat attgccgtat tgtttccaaa tcgtagtgaa
    29401 atcagaaatg atgccaggtt tttcttcact atcagttgca gcaggctgat ctttgactgc
    29461 ttggtccata attttggttc gttcatcgtt agagatgcca gaaagaatct ggtttacttt
    29521 ttggatatcc gggtcgcctt tacgcatacc aacagaaatc tgaacatctt ccgggtttgt
    29581 ctggaagcca tctgcaccgc tgaattcaag catttccaag tctttgttca cactagttgc
    29641 cgttacacct tccggacgtt cgctgacata accatcgatc attccagaag ctaaagctgt
    29701 tctcattgct gagaaattat ccattgcttg ttgtttctgc acatctggta tctgatcgat
    29761 cacagtatag tggaatgtat ttaactgagc agtaatcttt gctccagaaa gatctgctaa
    29821 actttttgct tttgcatatt tgctatcttt ttgaactact actactaatt gtgattcgta
    29881 ataaggatcg gtaaaatcaa tttcttttcg tcgttcagca gtagggctca ttccggcgat
    29941 gatcgcgtcg atcttgcctg attgaagggc aggagccaga ccatcccatt tcgtttggac
    30001 gatgactaat tttttcccta aaccatctgc tactttttta gcgatttgaa catcataacc
    30061 gccggcgtaa ctattttggc cttgaattgg caaggcatta ttctcatctg tttgttgaga
    30121 ccagttgaag ggtgcatacc cagcctccat acctacgcga aactcatcgc tcggtgtttt
    30181 ttcatctgca tttgccagag atcccacact gaatagtgag aagacaaaag caaatagtac
    30241 ggcaactgaa accatatttt ttttcatttt tttctccctt tctgattata tgatacacga
    30301 gcggtctaga tgaaatgcgg taaagcttta tctgaaaaaa taaaaagcga ccgatttata
    30361 gatataaaaa ggccgctaaa attccataag gtgataaacc tctcacaaaa catagcgcaa
    30421 cttagcatca ctgctaagac agtccgcaag ctcttaactt gcgtcccaac atacactcca
    30481 agcaaaaaag tgcacatttc ggcgatcctc cctattcctg cttctccatg tttgcttcac
    30541 tccacagggt taatgattct cgcgacctct acctcattga ttgaggcatc tcgtattcag
    30601 ttatttatac aaaaaaagtt tacgatactc gagaggcttt gtcaatctat aactgctgtt
    30661 ttttgaaaaa atactgataa atatagaaat ctttactttt accgaaaaaa caatcaaaat
    30721 gtgaatcatc tatccattgc aaacgatagt ataattatac acaaaaatgt atgtaataca
    30781 ataaaaaaag aactagaaca gaaaatttcc tgtgtccagt tccatctcga tcatttaagc
    30841 tgccgctttc tttggctcac gtcctaggat cgcttgcaaa agaacaacga cgccataaat
    30901 ggctaatatt agataaatca aacttgagta ttgggtgatt ccccagcccc atgttcgata
    30961 tacggctaat gtaatggcta aaacaattgc ggcaatcacg ttgaataaag caaaagccca
    31021 aagatttcca ttttctttgc gtacaagata aaaaacagag aaataaacgc ttaacgctaa
    31081 ccaggcgata caagccagaa taacgcccca ataaataaag aatggtaaca tatcgattca
    31141 cctcactttt atacagcagt attgtaacac gttttcattc ttttgtcagt gaacattgtg
    31201 ataaattgtt caaatgccca taacactttt ttattcccat ttttctgact tttcaacaat
    31261 aaatttgttc gagtatgggc tataatggaa agtgaggtga caaaacatga aacaattaac
    31321 agtagacgaa gcagcaaaag agatattagc ttatcagcaa attacatttt tgaccggtgc
    31381 aggggtatcc acaccttctg gagtgccaga ctatcgatct ttgtcaggaa tctaccacgg
    31441 gatggagcag ccggaatact tgctgagtca tcaagcaatg gtgaatgaac cggataaatt
    31501 ctatcaattt gtcaaaaaga tttatcatcc tgaagcaaaa cccaatatca ttcatttgga
    31561 aatggcacat ctagcgaaag aaaaaaatgt ttgggttgtt tcccaaaaca tcgacggttt
    31621 gcacgcaaag gctaaaagcc cgcaactcgt caattttcat ggaagtttgt atcaatgtca
    31681 ttgtcgaaaa tgtcaacaaa cggtagactg gaaagaatat cttcacagcg acaaacatca
    31741 agcatgcgga ggacaaatac gcccagacat cgtgttatat ggtgaagggt ttcaagatgg
    31801 agtcatggag caggcggctt atgccgtcag ccaagcagag ctgatcgtca ttgttggaac
    31861 gagttttcaa gttcatccgt tttgtgatct ggtacagttt cgccagccgt cagccaaaat
    31921 cttagtaatc aatcaaacgc ctgtttattt agcggagcct tatacgttta ttcaagaaga
    31981 cggagcggtt gttttcaaaa aaatacaaga attaggagca gattatgact gaattcaaaa
    32041 ccgaaaaaga aaaaatgatt gcaggcgagc tttattttgc caatgatcct gagctggttg
    32101 ccgaccgtat gtttgcaaga agtcaaagcc aaatcatcaa ccaagcagaa tcagcggaac
    32161 tgcgatccca attgttgaaa gagacttttg gccgtacagg gaaaaaaatc tatatggagc
    32221 cagttatcaa ttttgattac ggatataata tatttgttgg ggagaatttt tatgcaaatt
    32281 tcaattgtac atttttagat gtcagcacga ttgaaatcgg tgataactgc atgttcgctc
    32341 cgaatgtcca gctttacacg gcgacgcatc cactacatcc agtgaaacgt aacagcggtc
    32401 tggagtacgc aaaacccatt aaaatcggta ataatgtttg gttaggcgga ggagttatcg
    32461 tcacgccggg tgtcactcta ggggacaacg tagtagtcgg cgcaggttcg gttgtgacca
    32521 aatcttttcc cgacaatgta gtgattgcag gaaatcctgc tcgtatcatc aagacagtag
    32581 aggaagaact aacagaagag tctcttgaaa cattacgtca taagatcgat atgatcgatc
    32641 gagagttgat tgctttatta gaaaaaagaa tggatacggt aactaaaata ggacaagtga
    32701 aaaaagaaga aaaccaagca gtttatgatg caaaaagaga gcagcaagta ttggataaag
    32761 ttgttagtct gctgaaaaat aagggatata aggaaacaat aacagatacg tatgttgatt
    32821 tgatgaaaca ctcgcgcgaa taccaaaaca aaatgaagga ggaataagtg tgatcgaagg
    32881 agagacacgg cgaaaacaaa tcatgcaaac cttggcaaat acagaaaaac cagtgagtgc
    32941 tagcaagttt gcgaaaactt ttggagtcag ccgtcagatc attgtaggcg atattgcttt
    33001 actacgagct gcaggtaaaa gtatcgtggc aacagcaaga ggttatatcc tcgaaacaga
    33061 agaaaccaat actgggcaca tcagtaaaat cgctgtccag catggaaaag atcaaacaga
    33121 agaagaactg agactaatcg ttgaaaatgg tggtgaaatc attgatgtaa ttgtggaaca
    33181 tcccctttac ggtgagttag caggaacttt gcacatcaaa acgccacaag atatcgattc
    33241 ctttatgaga cgttatcaaa aaagtaatgc tactttgtta tccgaattaa caggcggcat
    33301 ccatctgcat acgatccgct acccagaaaa gcatatgctg aaaaacatca aacaaaaact
    33361 agctgaagca ggaatcctct acgaaggata acatcgtagc tgctactttt tatcctagaa
    33421 actattctat catctctgag ataaacaccc atatggaaga aataagaaaa aataagaaaa
    33481 gatgcgtatc caatacacag aattttttgg aattgcgatt tctagatgtc tatctaaatt
    33541 tcgattagtg gagaaacata aaaaagggaa gtgcagcttt tgagcactcc ccttttttat
    33601 aaagctttct tgtagcatag tatcgaagga acctgccaat tctctactcg atcaccaata
    33661 cgccttcttt tagtgcaaat ggattttgat cgttgatgtg gtcatagaac atcacaccgt
    33721 tgatatggtc gatttcatgt tgaacgacga tcgattcata attcttcaaa cgaatcttgt
    33781 gtttttcacc attcatatca taataagaca cagtgatttt ggcatggcga acaacatatc
    33841 ctggtacttc tcgatcaaca gataaacagc cttcaccttc ccctaaacaa gcatcttgaa
    33901 cagaatggct caaaatttta ggattataca taacagtact tagagaaggt ccatctgcct
    33961 ctgggtcagg acttggtacg tgaacagcaa tgattctttt agaaatatct aattgaggag
    34021 cagctaagcc aacaccgcct cgtaagtgta gttcttcagc tttgattgga tcttggctgt
    34081 tttttaagaa ctcaagcatc tcttttccta aagagatatc ttcttcgctt aatggaagag
    34141 aaacttcttt tgcaacttcg cgtaaggtcg gatttccttc acgaatgata tcatccattg
    34201 taatcatgga atatgtaccc ctttcttaaa agactgtgtt tcaagtctat tttcgcatta
    34261 tagtttacca caaaaatgga aaagtagtag taagattgtt tgaaaactac cttttcttaa
    34321 tgattaacta cttgattttc aacccggttt caggtaaagt atagctgtgt gctctaggca
    34381 catgacctgc cacttggtta agcgaatcac caacgtttta ctcagtcgca ggggaataat
    34441 cgaaagaggt gaaagaaatg gcaatttcaa aagaacgcaa gaatgaaatc atcaacgaat
    34501 acgctcgcca tgaaggggat actggttctc cagaagtaca aatcgctgta ttaactgaag
    34561 aaatcaacca cttgaatgaa catgcacgcg tgcacaaaaa agaccatcat tcataccgcg
    34621 gcctaatgaa aaaagttggt caccgccgta acttgttagc ttacttacgt aaaactgacg
    34681 ttcaacgtta ccgcgaattg atcaaacgtt taggcttgcg tcgttaattt tagtcaaaaa
    34741 gagtgggatt cacatgaatc tcactttttt tactcgtata tcaattaagt aaaattccgt
    34801 gatcaagcta gatggactcc tactaaccaa atgaaagctg ctcaaaagac ggctttcggc
    34861 agttttcatt tgtttagtag cgtcttgctt tcacgagaag gaaaaggaga agttatgtca
    34921 gaaaaacaag tattcaaaac gacatggggc ggccgtccct tacaaatcga agtcggtcag
    34981 ctagcaaaac aagcaaacgg agccgtttta gtccgttatg gagatacagt agtcttaagt
    35041 gcagctgtgg cctctaaaga agcaaaagat acagactttt tcccattaac gatcaattat
    35101 gaagaaaaaa tgtatgcagc agggaaaatc cctggaggtt tcatcaaacg agaaggccgt
    35161 ccaagtacgg aagcaacatt gactgcccgt ttgatcgacc gtccaattcg cccgatgttt
    35221 gcagaaggct tccgtaatga agtccaagta acgaacatcg tgatgagtgt agaaacagac
    35281 tgctcgccag ctatggcagc aatgctaggt tcttctttag cactatcaat ctcagatatc
    35341 ccatttgacg gcccaatcgc aggcgtagaa gttggtcgtg taaatggcga gtacgtcttg
    35401 aatccaacag tagaacaagc agaacaaaca gatatcgaat tgactgttgc cggaacgaaa
    35461 caagccatca atatggttga aagcggcgcg aaagaagttt cagaagaaga catgcttggt
    35521 gcattgctgt ttggttttga cgctatcaaa gagttagttg ctttccaaga agaaatcgtt
    35581 caagcagtag ggaaagaaaa aatggaagtg actttactgc aagttgatga agtattgaaa
    35641 aaagaaatct ttgatgcttc ttacgctaca atgaaagcag cagtaatgac tgaagaaaaa
    35701 cttgctcgcg aagataatat cgagcaggtg aagatcgata tccgcgaagc ttatgctgag
    35761 aaatttgcag gtcatgaaga tgaagatcac ttgttgaaag aagttaaaca aatcacagaa
    35821 gatcttgaaa aagatgtcgt acgtgaattg atcaccatcg ataagatccg tcctgacggg
    35881 cgtaaattgg atgaaatccg tccattgtca tcagaggtca gcttattgcc acgtgtacat
    35941 ggatcaggtt tgttcacacg aggacaaaca caagctttat cagcttgtac actcgcacct
    36001 ctaggagagc accaaatcat tgatggttta ggggtggaag tcagcaaacg attcatccac
    36061 cactacaatt tccctcaatt ttctgttggt tctacaggac gtgcaggctc tccagggcgt
    36121 cgggaaatcg gacatggcgc attaggtgaa cgtgcgttag cacaagtaat cccttcagaa
    36181 gaagaatttc cttatacgat ccgtttagta gcagaagtat tggaatcaaa tggttcttct
    36241 tcccaagcaa gtatctgtgc tggcacatta gcattgatgg atgcaggtgt accaatcaaa
    36301 gcgccagtcg ccggtattgc gatgggactt gtttctgatg gtgaaaacta tacgatccta
    36361 actgatatcc aagggctgga agatcatctt ggcgatatgg actttaaagt tgccggtaca
    36421 aaagatggta tcactgcttt acagatggat atcaagattc aaggaatcac agaacaaatc
    36481 ctaactgaag cattaactca agcaaaacaa gcacgtatgg aaatcttaga agaattgact
    36541 tcaacgattg ctgctccacg tgaagaatta agccaatatg caccaaaaat cgaaatgatc
    36601 cagatcgaac ctgctaaaat caaagatgtt atcggtaaag gcggcgatac gatcaacgga
    36661 atcatcgatg aaactggtgt gaaaatcgat atcgatcaag atggaaaagt aagtattgct
    36721 tcagctgatg cagaaatgat caaaaaagct atcaagatca tcgaagattt gaccaaagaa
    36781 gtcaaagttg gtgaagttta tctagggaaa gttgtccgta tcgaaaaatt cggtgcattc
    36841 gtcaacttga tcaaaggaaa agatggactt gtccatattt cccaattagc aaacgatcgt
    36901 gtcaataaag tcgaagatgt tgttaaacta ggtgatgaga tccttgtgaa agtaactgaa
    36961 atcgataaac aaggacgcgt aaatctgtca agaaaagcaa tgttgaacga agatggttca
    37021 acgaaaaatg aagaaaaata atttaattca taggaataat gtacttgtga tcgtgaaggt
    37081 gacaggggga caataattat tcgaaaaaag gggactgtga caaaagccgt gtcacagtcc
    37141 ttttttttcg aataaacggt gttcaaaagc ttgcatctgc ggtaataagt ccagccaagt
    37201 taaaaacatt aggagctgtt tttatttggc tgttcttatt acttgatgca gaacagcttt
    37261 tttacaacct ctccaataaa cgatgttcaa tcagctgtcc ctcgatatta gctcaaaaaa
    37321 cggcaaaata tgaggaacta tttttccgtt tgtttctcta atactcaggt caaaccgctg
    37381 atttcacaac ctctgattca cggtgttcca gaagcagctt ctacggaaat aagctgaaca
    37441 cttttgttac aacttctttt tttctggagt ttcttggcgc atatttttgg agtccttctg
    37501 aataaagcgt aaaataaaag tgagaaatat ggataaagga gggaaaggag atgctgaatt
    37561 ttttatggtc gttatttatc ggcggtatat taggtttgat agctggcgca attttaggaa
    37621 aggaagtccc gggaggcgta tctggaaata tcattatcgg ttttttaggt agttggctcg
    37681 gcgaattttt actaggacca ctgggaccgg aactcggcgg tttttatttg ataccagcat
    37741 tattgggtgc aattttttgc cttgctcttt attcatttgt ggcaagacgt atcagagaac
    37801 gtccaaagaa agaataattt tattcaaata agttgacact tcagtgtgtt acttggataa
    37861 ttagaagcaa tttaggaaag cgggtgtcat ggataagaat atcatctatc attcaagctt
    37921 acctaaagga tatccatata acaagaaatg agggaaaaac gtggcaacaa cgcacaatac
    37981 caaaaagata tcaatgactg gcctgcttgt agcgatggga gtcgtctacg gagacatcgg
    38041 gacaagtccg ctttacgtta tgaaatcgat tgttgaagat aatggcggat tgtcaggaat
    38101 caatcctgat tttgttatcg gatcagtctc attgattttt tggacattga ctctactgac
    38161 aacaatcaaa tatgtcgtga ttgcattgaa tgcagataac catggtgaag gtggaatttt
    38221 ctcactctac acacttgtcc gaaaaggtgg gaaatatttg atcattcctg caatgatcgg
    38281 aggagctgcc ttactagcag atggggtatt gacccctgct gtgacggtaa cgactgcgat
    38341 tgaaggcttg cgaggaattc cgcagttttt tgaccggttc ggtaataacc agaacgtgat
    38401 cgtcattatc actttagtta ttatttttgt tttattcatg gtccaacgct ttggtacaga
    38461 tattgtcgga aaagcattcg gaccaatcat gttcgcttgg tttacttttt taggcgtaat
    38521 gggattaatg aacttcagtc aagactggac agttatccgt gcactgaatc cttattatgc
    38581 tatccagctg ctttttagtg cagataacaa attaggcttg ttcattcttg gaaatatttt
    38641 cctggctacg acaggtgcag aggcgcttta ttccgatctt ggacatgtcg gcaaacgaaa
    38701 tattcgtctg agctggcctt acgtcaaaat ttgtttggtt atcaattatt ttgggcaggc
    38761 tgcgtggttg ttgaatgttt atcaaaaccc tgaagcacag caaatcaaga acctgaatcc
    38821 attcttccaa atgatgcctc aaagttggat cgtgatcggc gttgcttttg caacagtcgc
    38881 tgcagtcatt gcttcgcaag cattgattac aggttcgttt acgctagttt cagaagcaat
    38941 caagttgaaa ctgctgcctc ggttaaagat catgtatcct gggaacagta tcgggcaaat
    39001 gtatatccca gcagtcaatc tgattttatg gatcgcctgt tctctagtgg ttgtcacatt
    39061 ccgaacgtct catcatatgg aagctgctta cggtctatcg atcactgtga cgatgttgat
    39121 gacaacagca ctgctttact tttatcttat ccaaaatggg cattctcgtt ggcttgcata
    39181 tttagttacc tttttcttcg gtgcgataga agtcgttttc tttatctcaa gtgttgtcaa
    39241 attcttccga ggcggttttg tagccgttct gattggtttg atcatcttag tcgtgatgtt
    39301 tatttgggaa caagggaaca ttattcgcga atcgtcaacc gaggatgtgt ctttgagaga
    39361 ttatatcccg cagcttagag aattacgtga tgatacttct ttaccaatct atcagacaaa
    39421 tgtggtcttc ttggttcctg atatggctga agataaagtt ggccgacagt tcatctattc
    39481 gattttagat aaacggccta aaagagcacg agtctattgg tttgttcatg tggaagtgac
    39541 ggatgagcca tatacgaaag aatatcaagt agatatgatg gacactgatt ttattgtcca
    39601 agtgaatctg ttcttaggtt tcagggtcca acaggaaatc aacgtatatg ttcgccaagt
    39661 catccatgat ttgatgaaac aaggccgttt gccaaaacag ccacaaagat actctctgac
    39721 accagggcga gaagttggcg atttccaatt tgtcctgatt gatgaagtag tttccaatgt
    39781 gacaactcta ggaaaatggc aacgtcaaat catgcaggca aaactggcaa tcaaaaaaat
    39841 cgctacctcg ccagaaacat ggtttgggct agagtacagc gaagtaaaac atgaaactgt
    39901 tccgcttatc attggaaata ctcggaaaac atggttgaaa gagcggttgt gaaagtagcg
    39961 ctttgacctg aactaatgtc gaatgtcagc tacttgaaca ccgtttatca gaggtcatga
    40021 aaaagctgta ctgcaacaag cagtaagaac gagcagataa aaacagcttc tcatgttttt
    40081 catctgtttg ggcttaatgc cgtagatgca agcttttgaa taccgttttt atcagaggtc
    40141 atgaaaaagc tgtttagcaa caagtaacgc aatgattttg aagtgataag gagatgtggc
    40201 tgaaaaatgc cgcatctcct tttttattcc taaatatgaa tacgcattat tttcaatctt
    40261 tttgtagaaa aagggtacaa tagaaaaaga gaaaggcggg agaatatggt tatcaatttc
    40321 attattttat ttttgatgat tgcaattact tcattttttg tagcaagtga atttgcttta
    40381 gtgaaaatca gacgatcaag attggaacaa ctagaaaagg aaaatgtaaa gaacgccaag
    40441 ctagctcttc atgttacaca ccatttagat aactatttat cagctagtca attaggaatt
    40501 acgctaaccg gtttgatcat cgggtgggtc ggtgaaggat ctgtcgcggc tttactagaa
    40561 ccagtgatcg gtaaactacc ttttagttcg gctattagca gtacaatctc tgtggcgctg
    40621 ggatttattt tagttacgta tatcgatgtg gttattggcg aactgcttcc taagagctat
    40681 agtatcgtca atacggagaa ggtcgtcttg ttcgtagtta aaccacttca ttatttttat
    40741 aaagtaatgt ttccttttat ttgggtattg aatcattcag ctgcagggct agggaagcta
    40801 ttaggtgtgc gtctcgtatc tgaaggagaa gagacattgt ctcaagaaga gctgacatta
    40861 gtcgcattga attcttatga aaaaggagag ttgaccaaag aagaatatta ttatttggaa
    40921 aacgtgtttg aatttgatga taccttggca aaagatatac aagtagaccg tacgtccatg
    40981 caagtattcg aagcttcaga aaccgtcaaa gaagcgataa aagcttcgat tgaacaagga
    41041 catactcgct atccggttat cttagaatca aaagacaatg ttttaggtta tgtcaccttg
    41101 ccagatttga tcaagcaatc ttataaagat gaccagctga cagtagaaca gttgattgaa
    41161 gagccgatcg taacaactga aacgatccct ataaaaaaat tattgacgat catgcgaaaa
    41221 aagggtaagc atattgctat cttaaaagat gaatacggag ggacaagcgg cttagtgacg
    41281 attgaagata ttttagaaga aatcgtcggg gaaatccgag atgagacaga tttggacgaa
    41341 gcattgatag cggaacagtc agatggctct tatatcatct ccggcaaact aacattagat
    41401 gatttccagc gttattttca tgtagagatt ccagagtttg aagaaacgaa ttttactaca
    41461 cttgcgggct ttgcttctag ccgatataaa gaaataaaag caggaacaat cattgagatt
    41521 gcatcattcc gtttcacggt attagaatac cagcatgcac atatcgatta tttcaaagta
    41581 gagtccacgg aaagaaaaac agaataaaag aaaaaaggct gtgacatttt ttgtcacagc
    41641 ctttttgtta tctaaaaaac ctgttttcgg taaacgaaga agatattttc aataaaagtt
    41701 ttcattttta gccgcaacga tttcttttaa tcaaggctat cttgcttctg catgttctaa
    41761 tgtgaaatgt tcctcttcac ccatgtgttt caattgtttc atcgaacgca tataagagta
    41821 aagcaacacg gcaacagaac cgatccaagc taaaggagaa gctgctgctg ctcctgggta
    41881 tccccacatt cctgtaagaa cgatagctgc aaaagaacgc ataagcaatt ccatcatacc
    41941 ggcgatcgta gggatcttgc tttgtccaag cccttgaagt gtgtagcgta aaatgaacag
    42001 gactgctaag atccagtaaa gagacccatt gatattgaag taggtttgtg ctaattcaaa
    42061 tacacgtgtt tctgatgggt taacaaacaa ttgaacaaag aaatgaccga agaaaatgac
    42121 gatagcacct gctaagagac taaatccgac actcatcagt aaagtttgac gtaccccttg
    42181 caagattcgg ccatattctt tcgcaccata gttttgtgca gtgaaagttg ccattgcaat
    42241 accaaatgac atcatcggct gatttgcaaa ttggtcgata cgaccagcag cggcttgagc
    42301 agctacgaca tctgtcccta gactatttag tgctgcttgt aacacgatag caccaacagc
    42361 gatgatcgaa gattgaaacg ccattggcaa agcagcattt aggtgtacag caaactcttc
    42421 tttttcaaat ttgaaatctt ttttgcgtaa ctgtaacaaa ggcatttttt tcttgatata
    42481 cactagacac agtacgctgg aagaaacttg tgcgattact gtagcaatag ctgcaccttc
    42541 cacacccatg ccaaaataga taataaagat caaatcaagt acgacgttga tgatgaccgc
    42601 aatgatcaga aagaatagtg gtgtgcggct gtcaccaagt gcgcgaatga cattagaaag
    42661 caaattgaaa ctgactgatg caaagatccc taataaaata attgaaataa atgtttgtgc
    42721 ttgatcaagt atttcaggag gagtttgcat caattgaagc atcggacgaa taaacaggag
    42781 acttaggaca gttaaaatca cagtgacgac aagactaatg acaacactag cagcaaaact
    42841 tttcttcaga ccccgataat cttttgcacc gtaacgttgt gcggtaataa tggctaaacc
    42901 agctgttaaa ccttgggcaa agccaatgat caaaaatgtc aggcttccag ttgcaccaac
    42961 cgctgccagc gcatttttac ctagcgtctg acccacgatg atcatatcga tcatattgta
    43021 gaactgctga aaaacatttc cgatcagtaa aggaacagtg aacatcaaaa tcagtttagc
    43081 ggggcttcct tttgttaaat cgcgcatctt ttaaactcct tatatcttta aaatttagtt
    43141 agtagtatat agcgtttatc ctgagaatac caattagaaa tcaatgataa tttatgaaac
    43201 tccataaaaa gaagccaaga attgagtcaa agaatcaaca acttggcctg gtctgtaaaa
    43261 taagggacat ccacgtttat ctatcacctt aatattgtct aatctcactt ggtaaaagga
    43321 tcgtttctct cgtaccgtca tcataggcgt atacttgagc aggaaattgg ttcgaatagg
    43381 caaacggcaa atcaatatcc atttccacat tgcttcctgc ttgagaaaaa tgcatcgtca
    43441 cttttccacg attttcgatc aaatcaaagg ttaatatatt ttctaatgga atgactccct
    43501 taagatctag gtcaataata aaccatatac tgtcaatcaa ttcatctggc aaacttgata
    43561 cgacaccaac tgaagcgtaa cggttgcggc tgctatcaaa actttcaaac atctgtttaa
    43621 cctccttcga atcaacgaat gttttatttt tataattaat cctaggataa actagaaata
    43681 cttacttcaa cgagggttca ttctaataaa gaatcaggaa aaatgcaaca ataattgaat
    43741 actttttttc aaagtataaa tttttataaa ggtacgataa aagtatgcga ggaaaagctt
    43801 ggtaaattag gatttttcgt ttgtaaagcc atttacaaaa gtggaagccc catatgaaaa
    43861 taaacgatta gaaataaaaa aggcgtgtta aaagctgctg acccgccgct tctaacacca
    43921 cctgattgtt tcagtattat tcttctgttg aaccgatcac ttctggttcg ccaccttcac
    43981 ctgtgctttc ttcttcttca ctttgagcga ctacagcagc gatttgctct tcactgtcgg
    44041 tcacgaattt gtaatcgtcg ttttttggaa gatcggctac tgtaatagaa tcacctaatt
    44101 ccaagtttgt cacgtcaact tcaattcgtt caggcaattt gtctggtgta gcagatacga
    44161 ctactgtata caagttttga gctaacactc caccagattt agcacccact gattcgccaa
    44221 caagaacgac ttctgtttcg acttctgttt cttccgacat gtttacagat agaaattctg
    44281 catgttcgaa atgattggta aaagtgttcg tttggatctt gtgaaccaat gtattgactt
    44341 tttgtccatc gatgtccatc gtgatgactg tgttcgctcc atgttcacgc aacaatttgc
    44401 ttagtgtcaa accatcgaat gagatagggg tactttctac tttataccca taaacaacag
    44461 ctggaacttt cccttcgtga cgaagtttgt ttcttaatga acggggacgt acttctcttt
    44521 tacttacttc taatgatact gacataacca aaattcctcc ttaaaatgtg actgtctgct
    44581 ttggtaacgg acagatttta tttaagtgaa ttctaaaggc taatctcgtg cacatcatcg
    44641 aaggcagggc gcttaaaaaa gcgcaaaagg agagatgcgc gcatctcccc ttagaaagtc
    44701 aggattcaac ttttctccac caggtcatta cgctgtgtat gagaaatcca attcacttta
    44761 ctatttaacc gtaacgtgaa ctgttaatta agtcaaggaa taactatgat gatgtatttg
    44821 caagcaagaa tattcaaggt ataattaatt agtagtaata agaaaggaaa cagcatgcgt
    44881 ttagataaat taatagaaga aaaattagaa acgacacgca aggaaatgaa gcggctgttt
    44941 gctttgaagc aagtgatgat agatggcaca gtcgaatttc gacaaaatcg aaatgtagat
    45001 agtttactgc atcaaatcga agtagcaggt gaacacttag aaacaaatga gtcctattat
    45061 cttctcaata aacctgaaaa agctgttaca gctgtatcag atccagaaaa gacgacagta
    45121 atcgatctga ttgcaagtgc cgatcgtttc caaccattat atccagtggg aagactagat
    45181 agagatacaa caggactatt gctgatcact tcgaatggac aattgggata tgaaatgcta
    45241 cttccagaaa aaaaggtttc aaagacttat caagtagttg tgaacgaaag ggtgacaccg
    45301 gcagacgtaa cagcatttga aaatggaatc gtattcgctg atgggtatca atgtaagccg
    45361 gctgatttaa aaatactcaa agcagacaag caccaaagta cggttttatt gacgatccaa
    45421 gaaggaaaat tccatcaagt caaaaagatg ttcttagccc aaggaaagaa agtgaccgca
    45481 ttgaaacggc taagcatggg accattggaa ttagatgaac agctaggagt aggcgagtat
    45541 cgatcgttga cattagcaga gatgaaaaag ttaagtattt attttaaata ggaggtcaaa
    45601 aagatgaaat ataaaacttt attgtttgat gtagatgata cattgttaga ttttcaatta
    45661 actgaagcca atgctttaag tgctttgttt gcagaacaag gaatcacatt gacaccagaa
    45721 atcgaaacca gctataaggc tttgaatcat catttatggc aggagtttga aaaaggcaga
    45781 ctatcacgag aagaaataat aggcagtcgt tttgggttac ttttccagca atttgggaaa
    45841 acagtagata gtgatcaaat ggaaaaacgc taccgccact acttgaacca aggtcatgat
    45901 cttgttccag gaagtctaga aatcctgaaa aaggtccatc cgcatgctga tctttatatt
    45961 gtgacgaacg gtgtgtcgca cacgcaacat cggcgattaa cagatgcagg aatgcttgat
    46021 tacttcaagg atatctttgt ctcagaagct gtcggagcgc aaaagccgat gaaagaattt
    46081 tttgatcatg tcttttccca cattcctaat tttgataaaa agcaaactgt gatcattggt
    46141 gattctttga cttctgatat caaaggagga aatatggcag ggatcgatac gatttggttc
    46201 aatagaaata aattaccaga aatcgaagaa atccagccta cttatcgaat cgattcatta
    46261 gaggaacttt attcattatt ggaaattgaa aaggattaat tttcagaaaa atatagcatt
    46321 ttcgtgtttt ttcgctataa tagattagaa tgaaaaaacg gatacgaaag aggttttagt
    46381 caatgacaaa aagcaagcca attatcattg gtgtgacggg tggatccgga agcggaaaga
    46441 caagtgtcag ccgtgcgatt ttcaacaact tcccggacca ttccatcatg atgcttgaac
    46501 aagattctta ttacaaggat cagagccatt tgagttttga agaacgattg aacacaaatt
    46561 acgatcaccc atttgccttt gataatgatc tgctgattca gcatgtaggc gacttactga
    46621 actataaagc cattgaaaaa cccgtgtatg actatgtagc gcatacaaga agtcaggcaa
    46681 cgatcattca ggaaccaaaa gaagtgatca ttctagaagg aatcctgatt ttagaagacg
    46741 aacgtctgcg tgacttgatg gatatcaaag tatacgtaga tacagatgat gacattcgta
    46801 tcattcgtcg tatcaaacgg gatatggaag aacggggacg cacattggac tccgtgatcg
    46861 aacaatattt gacagttgtt aaaccgatgt atcatcaatt tatcgaacca acgaagcgct
    46921 atgcggatat cattgttcca gaaggcggag aaaaccacgt tgctattgat ttgattacaa
    46981 caaaagtagc tagtttctta aaccataaat agtgcgcagc gaaacagttg aacggactgc
    47041 gaccgtttga aaagcaagga ttctgctttt tgaacagtca ccagccaact gtttttttat
    47101 ttataacaag aggttgtgaa aacagcatct tgacctaagt attaaaaaga agaaacggaa
    47161 aatagctgtt tatattttac cgttttttga gctaataccg aaggtcagct gattgagcac
    47221 cgtgaagtag aggttgtaaa aaagctgtct ttgcatcaag cgataagagc atccaaataa
    47281 aacagctcct cacgtttttc gttgggttgg gcttattatc gtagatgcaa gcttttgaac
    47341 accgtttaac gagaggttgt aacagaagtg gtcagatgca ataaataaga agaaacttac
    47401 gaaaattatt tctcgaattt gtgtgagatt tcgacttatt tttttgaaga agctcttttg
    47461 tcgcaccccc
//
LOCUS       DAZKCW010000021        46191 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000021 DAZKCW010000000
VERSION     DAZKCW010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.021"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            161..1042
                     /locus_tag="ACG84Z_001238"
     CDS             161..1042
                     /locus_tag="ACG84Z_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFP9162091.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            1055..2665
                     /locus_tag="ACG84Z_001239"
     CDS             1055..2665
                     /locus_tag="ACG84Z_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162092.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2742..3401)
                     /locus_tag="ACG84Z_001240"
     CDS             complement(2742..3401)
                     /locus_tag="ACG84Z_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFP9162093.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3684..4349)
                     /locus_tag="ACG84Z_001241"
     CDS             complement(3684..4349)
                     /locus_tag="ACG84Z_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFP9162094.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4496..5101)
                     /gene="dhaL"
                     /locus_tag="ACG84Z_001242"
     CDS             complement(4496..5101)
                     /gene="dhaL"
                     /locus_tag="ACG84Z_001242"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFP9162095.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(5129..6139)
                     /gene="dhaK"
                     /locus_tag="ACG84Z_001243"
     CDS             complement(5129..6139)
                     /gene="dhaK"
                     /locus_tag="ACG84Z_001243"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFP9162096.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(6114..6509)
                     /gene="dhaM"
                     /locus_tag="ACG84Z_001244"
     CDS             complement(6114..6509)
                     /gene="dhaM"
                     /locus_tag="ACG84Z_001244"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFP9162097.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            6663..6983
                     /locus_tag="ACG84Z_001245"
     CDS             6663..6983
                     /locus_tag="ACG84Z_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFP9162098.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(7095..7952)
                     /locus_tag="ACG84Z_001246"
     CDS             complement(7095..7952)
                     /locus_tag="ACG84Z_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFP9162099.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(8060..9364)
                     /locus_tag="ACG84Z_001247"
     CDS             complement(8060..9364)
                     /locus_tag="ACG84Z_001247"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9162100.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(9361..9870)
                     /locus_tag="ACG84Z_001248"
     CDS             complement(9361..9870)
                     /locus_tag="ACG84Z_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162101.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(10045..12180)
                     /locus_tag="ACG84Z_001249"
     CDS             complement(10045..12180)
                     /locus_tag="ACG84Z_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFP9162102.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(12263..13918)
                     /locus_tag="ACG84Z_001250"
     CDS             complement(12263..13918)
                     /locus_tag="ACG84Z_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFP9162103.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(13920..14234)
                     /locus_tag="ACG84Z_001251"
     CDS             complement(13920..14234)
                     /locus_tag="ACG84Z_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFP9162104.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            14404..14664
                     /locus_tag="ACG84Z_001252"
     CDS             14404..14664
                     /locus_tag="ACG84Z_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFP9162105.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            14678..14992
                     /locus_tag="ACG84Z_001253"
     CDS             14678..14992
                     /locus_tag="ACG84Z_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFP9162106.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(15722..16276)
                     /locus_tag="ACG84Z_001254"
     CDS             complement(15722..16276)
                     /locus_tag="ACG84Z_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFP9162107.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(16402..18331)
                     /locus_tag="ACG84Z_001255"
                     /pseudo
     CDS             complement(16402..18331)
                     /locus_tag="ACG84Z_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(18637..19353)
                     /locus_tag="ACG84Z_001256"
     CDS             complement(18637..19353)
                     /locus_tag="ACG84Z_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFP9162108.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(19354..21177)
                     /gene="glpO"
                     /locus_tag="ACG84Z_001257"
     CDS             complement(19354..21177)
                     /gene="glpO"
                     /locus_tag="ACG84Z_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFP9162109.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(21191..22687)
                     /gene="glpK"
                     /locus_tag="ACG84Z_001258"
     CDS             complement(21191..22687)
                     /gene="glpK"
                     /locus_tag="ACG84Z_001258"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFP9162110.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(22823..24283)
                     /locus_tag="ACG84Z_001259"
     CDS             complement(22823..24283)
                     /locus_tag="ACG84Z_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162111.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(24273..25568)
                     /locus_tag="ACG84Z_001260"
     CDS             complement(24273..25568)
                     /locus_tag="ACG84Z_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFP9162112.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(25900..26577)
                     /locus_tag="ACG84Z_001261"
     CDS             complement(25900..26577)
                     /locus_tag="ACG84Z_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFP9162113.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(26607..27698)
                     /locus_tag="ACG84Z_001262"
     CDS             complement(26607..27698)
                     /locus_tag="ACG84Z_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFP9162114.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(27799..28233)
                     /locus_tag="ACG84Z_001263"
     CDS             complement(27799..28233)
                     /locus_tag="ACG84Z_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFP9162115.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(28817..30274)
                     /locus_tag="ACG84Z_001264"
     CDS             complement(28817..30274)
                     /locus_tag="ACG84Z_001264"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9162116.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(30271..32166)
                     /locus_tag="ACG84Z_001265"
     CDS             complement(30271..32166)
                     /locus_tag="ACG84Z_001265"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFP9162117.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(32224..33999)
                     /locus_tag="ACG84Z_001266"
     CDS             complement(32224..33999)
                     /locus_tag="ACG84Z_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFP9162118.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(34049..35545)
                     /locus_tag="ACG84Z_001267"
     CDS             complement(34049..35545)
                     /locus_tag="ACG84Z_001267"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9162119.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(35739..37361)
                     /locus_tag="ACG84Z_001268"
     CDS             complement(35739..37361)
                     /locus_tag="ACG84Z_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFP9162120.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(37689..39002)
                     /locus_tag="ACG84Z_001269"
     CDS             complement(37689..39002)
                     /locus_tag="ACG84Z_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFP9162121.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(39247..39471)
                     /locus_tag="ACG84Z_001270"
     CDS             complement(39247..39471)
                     /locus_tag="ACG84Z_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162122.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(39491..39913)
                     /locus_tag="ACG84Z_001271"
     CDS             complement(39491..39913)
                     /locus_tag="ACG84Z_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9162123.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(40055..40765)
                     /locus_tag="ACG84Z_001272"
     CDS             complement(40055..40765)
                     /locus_tag="ACG84Z_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFP9162124.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(40783..41280)
                     /locus_tag="ACG84Z_001273"
     CDS             complement(40783..41280)
                     /locus_tag="ACG84Z_001273"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9162125.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(41317..41769)
                     /locus_tag="ACG84Z_001274"
     CDS             complement(41317..41769)
                     /locus_tag="ACG84Z_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9162126.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(41904..42509)
                     /locus_tag="ACG84Z_001275"
     CDS             complement(41904..42509)
                     /locus_tag="ACG84Z_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFP9162127.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(42959..43579)
                     /locus_tag="ACG84Z_001276"
     CDS             complement(42959..43579)
                     /locus_tag="ACG84Z_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9162128.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(43581..44450)
                     /locus_tag="ACG84Z_001277"
     CDS             complement(43581..44450)
                     /locus_tag="ACG84Z_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFP9162129.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(44473..44880)
                     /locus_tag="ACG84Z_001278"
     CDS             complement(44473..44880)
                     /locus_tag="ACG84Z_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFP9162130.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(44899..46188)
                     /locus_tag="ACG84Z_001279"
     CDS             complement(44899..46188)
                     /locus_tag="ACG84Z_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9162131.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        12980 a         9848 c         7901 g        15462 t
ORIGIN      
        1 gctagcaatt ccttgtttat gaattcattg acagaaattt ataaaaagaa tattatgtac
       61 taaaataata aaaaaagttt tataaaaagg tataaaacct ttttattaaa ctatttaatc
      121 ttgtttagta tatattttta gaaaaaggag tggggttttt atggcagaaa tcgtcaaagt
      181 cacacatttg aaaaagagct ttggtcgttt cgaagcttta aaagatgtct ctttcaccgt
      241 acattcaggt gaagtcgttg gatttatcgg accaaatggt tctggaaaat ccacgacgat
      301 tcggacactt ttagggatta taaaaaaaga cggcggaacg gcaacgattt ttgggcaaga
      361 tgtatgggaa gatagtttat ctatccatga acgtctttct tatgttccag gcgatatctc
      421 tttgtgggga aatttgactg gaggagcgat catcgatctc ttcatgaagc ttcatggaaa
      481 agggagtgct caaaaaaaag atgaactgat tcaacgtttc tctcttgatc ctaagaaaaa
      541 agcaaaaaac tattcaaaag gaaatcgcca aaaagtgggc ttgattgctg ctttggctgt
      601 tgattcggat ctctatttat ttgatgagcc tacttctggt ttagatcctt tgatggaaac
      661 gattttccaa gaagaagttg aaaaattgaa agaacagggc aaatccatcc tactttcttc
      721 tcatattctc agtgaagtcg agcgactagc ggataaagtc gtgatcatac gcgaaggaac
      781 actcgatgaa gaaggaacac tcgatgaatt gcgtcatttg actcgttcga ccatcactat
      841 agaaacagaa gcagagaata gtcacttagc acaattgaac ggtgtccatg actttgtgca
      901 aaaaggtcac ctcgctcaat ttgctgctga taacgaagct ttcgatgtga ttttagctga
      961 agcgtccaaa ttaggtgtga aaaaatttga atctattcca ccgactcttg aggatttatt
     1021 catgagacat tatgaaggat gaggaggaag cgaaatgact gataaatttt cacgctggtc
     1081 cacccttttt tctcaaaacc ttagccgtga ctggaaaaag atcctgatat ggctagtcgg
     1141 tgtcactgct ttttctggtg gttttgtccc tgcgtttgaa gaattgactt ccggacaagg
     1201 attagctgga ttatacgaaa ccttgcaaaa cccggcaatg attgcaatgg tcggaccaac
     1261 tccagcttcg aatgctgctg agtatacttt aggagcgatg tatgcaaatg aaatgttgct
     1321 tttttgcagt ttgtttgctg ctgtgatctc tgttttacac gtggtgagcc aaacgagaaa
     1381 aaaagaagaa cttggtctga ttgaacttat tcgttccttt cgagtcggac gtcaagcaaa
     1441 ctctttagct gtcatcgctg aaagtattct gatcaatttg cttttagcaa tatcgatcag
     1501 ctgtacgatg atttttttcc aagcggattc gatcactgca gaaggtgctt ggctttttgg
     1561 gctatctgta ggtagtatgg ggattttggg gagtgccgtt gcactgtttg ctgcacaact
     1621 gatgccaagt tcagccagtt cgaatggtct gtctttagcg tttttaggtg gactttacct
     1681 tctacgagca ataacagatg tagctgattc ctccctttcg atgtggaatc ctttaggctg
     1741 gtcttatttg acctatccat ttacaactaa caactggatt cctttgcttt atttgttttt
     1801 gttcagtcta atcttgataa tcagttcatt tgttttagag gaacatcgag atttgaacac
     1861 cggctatatc cccgaacgtg aaggaaaacc gtatgctaaa cgttctcttt tatccttgcg
     1921 tggtttatta ttctatctaa ataaagggat gacaatcagt tggcttatca cttttggttt
     1981 gatgggggcg gcatacggct ctatctacgg gaatatgcaa cagtttttag aaagtaacga
     2041 cttaatgaaa cagatgttta tccaatctgg cgtctcaatt gaaaaaaact ttacaagcac
     2101 gatcatggta gtcttgattt gtctagctgc tattttacca attgctagca tcaatcgttt
     2161 atttacagaa gaaacccacg gacgtatgaa tcagctgttc gcaacaaaaa tttctaggaa
     2221 ccaactttat tggaccaata tgttactagc tattctattt gctatattgg caatcctgat
     2281 tagttctggt gcactagggc tttctgcttt ggcttcgatg aaggatgcga aagacatgga
     2341 tctattgatg tttcttaaag ccgggttcaa tttcctgcct gccgttttag tgtttatcgg
     2401 aattagtggc tttctattcg gatggcttcc tcgaatcggt aaacttgctt atatctactt
     2461 agcttactcc tttgcactca attactttgg cggaattttg gatttaccag aatggttttc
     2521 caaaacagct gtccctagct gggttccacg gatgccaaac gattcttttg atctttccgt
     2581 gttccttacg ttatcatgta tcagccttgc actgttcgtc cttggttcta ttggttatag
     2641 gcgaagagac ttactagaag gataataaaa aagcatgtac aatttcatgc tagcctccaa
     2701 atctgggtca aaaatccaac atttggaggt cattttttta tttacaagtc ttctaactgc
     2761 tctttatcaa tgatccagac ttctcgattc tttcttttta cataaccatt ctcctctaat
     2821 aatttaaatt ttctagataa agtttcgggg gtcgtaccga taaatgcagc aagttctttc
     2881 attttcattg gcaggaaaaa gtgatccttc cctgtcgctt tagctaagtc aagcagatag
     2941 acagcgactc gttcttctac tttttccatc atcaaaaaag ttgtctgctg ctgtactttt
     3001 gttaatttct caacgttgat tgctaaaagt ttcagactaa gggcgggata atgcagtaag
     3061 agttccgaga aatctttttg tctcaatatg caaatttccg ttttttctag tgcttcgcca
     3121 aataaagact catttggaac gcctagcaac tggctctctc cctcatatcc gcccggctct
     3181 attactcgta aaagctgttc ctttccgcta gcagataatt gatacacttt catactgccg
     3241 gaggccacga tcactaattg aggttctcca ttcggcgcaa gaatctgttc tcctttttcc
     3301 acatagtgat gtttgacaag tgcgtgtact ttttcttgat cttgctgtac taagtgattg
     3361 aacaaaggaa caaatgaaac acataaatga tcatgactca taatctctcc tccttctaaa
     3421 cagctatttc taataaagaa acataacttc ccttattcca actgataatt ttcttttatc
     3481 atagcataaa cgtcaagcga accagatacc agcaaataga gtggatttct ttttgtccct
     3541 tgctttattt tccttctttt gagaccttaa gtaattgatt cctatcaatt ttttaaatat
     3601 ttactttttg aataatcaaa aacaaacctt cactcgcaag ccgagagtaa ggtttgtttt
     3661 tcgcattgct tatttcgtgt tgtctattga aatttttccg cacctagctt ttgatatagt
     3721 ggtgctagtt cttgtaaggt ttcagcggtt atttgctcaa cgtgttcgat ttcttgcgga
     3781 tagaagaata gtttacccat ttgaaaggtt cggtctctca tcgctttttt caactcttct
     3841 tgtttctttg tatcggacaa atagtcagac aaagctaagt ggtcgtcaag ttcatgttct
     3901 ggttgcggcc atatgtaata atccttgata tcgactgttt tgctccactc tttcagtatc
     3961 gcaagcaact ggttatacgc tgcaatgcta ccatatcgtt cttcgctttt ataatgttgg
     4021 tacatcaaat agatttggta ttgtttttga ttcaacaaaa ctgctagaca ggcattctcg
     4081 tcttgacgag attcgcttcg gtacgcgctc caaaaatgac tgcgtaaatt ccagccattc
     4141 gtccagcttt cgattttagg tttgctcatg ccgtacatat caggcaaaag tgcagctgtc
     4201 tggagctgaa tctctttcca tttttgccag tgttctttat attctttctt gatttgttca
     4261 atcttatctg ttggatggct ctctttgagc tgtttgaatg cgtagattgg tcgatcaaac
     4321 aactgataat ctgattttcc aagttccatt gtttcgcctc tttccgttat cttttgtatt
     4381 ctacctgaat tttgcgatat ggacaaatag aggttgtgaa aaagctgttc tgcatcaagt
     4441 cataagaaca gccaaacaaa aaactgcgat gagcatcacc gcagttttat tgaacttaag
     4501 gttgattgat cacatctaaa agcgttgaaa ataaaatggc actagaagca gctcctgggt
     4561 cgatatgtcc gattgcacgc tctcctagat aggaagctcg tcctttttta gctaccaaga
     4621 ctttggtgtg ttcttttgcc tggtcaatga tttcttttgt taaattccct gccttcaatg
     4681 cctctgtgac tggcagccaa acatctaaca tcgttttatc gtcagcttct gcctttcctc
     4741 ggctttgaat acccgctgtt ccctgctcga tcacttcgcc taatttttct tgagaatcaa
     4801 tagaatcgac ctcttttgtc gctttcatca tgttcatgaa tgcagatccg tataacggac
     4861 cagaagcccc accgactttc gatatcatcg ccatagagaa tactttgaat gtatcgctga
     4921 ttgtttcagg atgatcggct tgaaaagctt cttcataagc tgaaacccct cttcccatgt
     4981 tatttccatg gtctccatcg ccaatcgggg tatctagatc actgagatat tgtttgttct
     5041 gattgattgc ctctgcaaat tgcgtgagcc attcttggat ttcttgaacg gttagtttca
     5101 tattatcacc cttttatctt gagatttttt accatgaaat cgtctgtaca ttgctttcta
     5161 aagaatcttt ccattgtgtc tccgtcaagt cgatcagtgt tagagaaaga ccttgcatat
     5221 ctagtgaggt cataaaatta ccgacttttc ggaaaactac attgacgcct ctttcttcca
     5281 acagagctaa aacatcattc atgaacacga actgttccat caaaggcgtc ccgcccattc
     5341 cgttgactag tacacctgct tcttttggta aattcgagta atcatctaaa atcttagtaa
     5401 caagttcctt tgccagtact ttagaaggct gcatcttttc tcgacgatag cctggctcac
     5461 cgtggatacc aacaccatac tcgatctcat cttctcctag ttcgaatcct ggtttcccta
     5521 cttctggtac agttgctgct cgaagcgcta gaccgatcgt cttagttgcc tgtacgacct
     5581 tttctcccag ttctttcaac tcagctaggg aagcaccgtt tcttgctgca tcgcccacga
     5641 ttttgtgtac aaggacagta cctgcaactc cgcgttttcc agcagtatac gtactatttt
     5701 caacggcgat atcatcatct acgatcacac tttctacttc aatatcgtcc atagcagcta
     5761 attcctttgc catatcgaag ttcaatgcat cccctgtata attcttaacg atcagcaaaa
     5821 ctccttttcc actatcggct tccttaatag ccgtctgaat ctgatctgga gttggagaag
     5881 taaacacatc accaagcacc gctgcactta acatcccttc ccctacaaac ccggcatggg
     5941 atggttcatg tccgcttcct ccaccagaaa ccaaaccaac ttgttccgct ttctgattct
     6001 tggctacaac acgggaagat tctacacgat gaacaagttc tggatagctt tttactaatc
     6061 cttccagcat ttcttcgaca atattgcttg gatcattcat gatttttttc aatttattcc
     6121 catcctttct ttccggcatt ttgtgcttct gttaagattt gctgagtatc atctgttata
     6181 ccggcagtga tggctgctgc aaaagctcct tccactaaag gcgcatccac cagatgataa
     6241 cgttgctgct gctcttcttc caacatgtct tttgccagtt ccgagttcaa taccgcgcta
     6301 ccgatatccg caaaaacaaa ataactagct gcatcgcttg attcattgac tgcttctacg
     6361 attttcatcg ggtctgatcc gatctcgcca tttattccgc cgagagaaaa aatttgcacc
     6421 tcttcggatt tttgcatctg ctcaatcatt tctttaatac catctgttac tttttgacta
     6481 tgagaaataa gcaaaatact ttttttcaca agaatcttcc tttcttttac atagttgcta
     6541 acgattggtt tcgctttcat taatgaacaa ttcaagtata taataaattt ctaattttgg
     6601 gaaaatatgt gtagtgcttc ttgaagtttg ttatacttta attaaaagag aggagtgatc
     6661 gaatgattac aacaacaacg aacagtgtag agggaaaagc cgtagtagct tataaaggga
     6721 tcgtttttgg tgaggtcatt actgggatcc atgcatttaa agacttggag gcggggttgc
     6781 gaaatatctt tggcggccgc tcaaaaagct atgaaaacga actaatgggt gcaagagaag
     6841 aagcacttgc cgaaatggcc gaacgtgcaa aagcattagg agctgatgcg atcattggcg
     6901 taaaaatgga ctatgaagta ttaggcagcg acaatggcat gctgatggtc acatgtagtg
     6961 gaacagctgt ctccacgaga taagtagggg acatctgttt taataactaa agagagatgg
     7021 gacatgtagt ggcactcaag aattagattt ttcagtctaa cttcgaggta ctctaccttc
     7081 ccatcctctc ttttttattt ctttttgcgg atgattccgt aagctgctgc gactaacaca
     7141 cccgcccctg ctaaggaata actgacagaa gctgtttttt catttgtttt tggcaaagtc
     7201 tgacttgttg atttggatgg ctctgtcgtt tgctgaactg tttctgtcgt gcttccagag
     7261 gtcactgatt tttctcctgc cgaatgcaaa atatctttta ttcgttggaa actagctgct
     7321 aagtcagctt tttttgcttc aaaatcatta gcaactgttt gtgcttcgct gatctttccg
     7381 tggattgctt gactggccgc tgtgatatcc gcttgagttt gacttagctt tccagaagct
     7441 gtttgagcaa cctgatttaa ttgctgattg aattcttttg cttgttggat cttcccgtca
     7501 agatctgttt ggacagcttc cgcttttgct ttcgcttcgg caagcttttt ctcaagttgt
     7561 gcacggtcat ttcccacttt atttttaaga tcagctaaat cttgatcgat tgctgcttgg
     7621 tcttctttca atttgttttt tgcagcttct aatgcttctt cgagttcttt tcttttattt
     7681 tccaagtctt gcaaatgatc gatttggtca gaagaggtag aactatttat tgatgtatct
     7741 tctgaagatg aaatcgtttc tcctgaatta tctgtcggta cattggaagt catttctgtt
     7801 tccgaggcac cgttttcagc accagaagag cttatggttg ttgaaggttc tgtttgagca
     7861 ggttcagaag tttccgcaaa agctgtctgt cccaataaga aaatactgga aacagcaatt
     7921 ggccagatta acggcttcat tctttttttc atcacttttc ccatccttac tactttttaa
     7981 ctaatttctt attataagca aaaatgtttg gaagaaccat aaacacaaca ggctgtttgt
     8041 ctaaaaaacg gtgcatcttt tatttttttg tacgttccgg gcttttccat gtcccgcttc
     8101 cataacctaa aatcgttttg actgctggaa tgaaagtcgt cacgatcgtt atcgcgttca
     8161 ctatccagaa caaaagcata tatagtggtg cgaaaagaag gtatttcaat tttcttcgtc
     8221 gatcatctac aatcagcgaa gctagcaact ggaaaaatcc tgcgaccatt tcaaagcaga
     8281 tgaacacaaa actgaatgta aaagtaatat aaatctgttc gtagtttcct tgatatacat
     8341 aatgcccgat taatccagca aaaagaacta cggaaataca aaagaatatt gaccagacaa
     8401 tactcaatgt ttgatcaatg aagatgatcg ttcttccaat atgtttaaaa ggatggagca
     8461 tcactttttt gaaattcgtc agccagactt ctgttccacc ttttgcccaa cgttttctgt
     8521 gtcgatatag catcttcaac gtcacaggta cttccatgaa aaagataatc tcaggagcaa
     8581 aaacagataa ccagtcattt aactgatgat cccaagcaat actgatgtct tctgtcgctc
     8641 gatcttgtct gaatccgccc acatcgatca aggcttcttt tcgatacatc gtatttgctc
     8701 cactgtacgc ataaagacca ccgaaaacag ctgactgtgt tcgtttaatg atgcccacga
     8761 tacttgagaa ttcaaccgtt tgagattttg caatcaattt ggtacgattt tggacatcca
     8821 tatttgcagt gaccgcagca atatgtcttg caccagggcg aatgaaataa ttcacatacc
     8881 taatcagtgc atctggctcc ggtaccgtgt ctgcatcatt gcttaaaatc aatttccctt
     8941 ttgcaaaggc aagtccgata ttaaacgcgt gggcttttcc tttatttttt tcgatccgaa
     9001 ccacacgaag attagcgtat tttttcatca gtctagctaa tatttctggt gtttggtccg
     9061 ttgaaccatc gtctgtcact aatacctcat agttgtgata attcaatttc gtcatcaaat
     9121 actcgattgt atattcgatc acaatttctt cattatgggc tggcaccatg atcgtgatga
     9181 acggttcgac actcaaggga acatctaccc attctttttg cttatgtttg tataaaaaca
     9241 cataacacca gacaccaata aaccatacaa atccgcctaa aatcggataa gaaacgagaa
     9301 aaaaatacat aatagacaaa caagtatcta agaataaatt acctgtatgg gtgattgaga
     9361 tcatttcagt tccaccccat tttctttata caaatctgca atgaatgtcg tatctagatt
     9421 tttctcttcg gagacagaat aaaaacggac cgtttctctc tcttcttttg ttccaaaacg
     9481 ttccgtatac acttcttcaa gtaattcttg tctttttttc aatttttcat cttcatattc
     9541 aaaagattta tttacttttt tgtatagatt tcgattgttc cacctagtca atacaaatga
     9601 ggtaatcagg aaactgaaaa aaatcaatac aaaaaagccg attaagaaat acagcatttt
     9661 cttttctgat aaaaaagcgt acaaggaaaa atccttggct ctttctggtc tcgttaatgg
     9721 gaaaaagacc catataaaag gaagaacaac gatcatccat cctaaaagag ccactaacgt
     9781 ttgccaaatc tttaaccagt aattaccttt tgaaaaatac ttatctttca ccaaaattga
     9841 tgcaacttct tctcttgtta cttttttcat atcctcacct cacgtttttt tgttacgacg
     9901 taggagttta ccatacattt catttctttt cacataaagt gttcctaaat ttttcctaag
     9961 aaaaagaaca aaacatttct catcagcaaa tgaaaaatat tttgttcttt ttatcagttg
    10021 ttctttttat tttttatctc ttaattatgt tgctctttcc aatacgacaa tgcttttcat
    10081 tcctctagat atcgccgtgt acatttgtct gcgtcttctt tgctcatctc catcgttttc
    10141 aaatggatat aagattacat gatcaaattc cagtcctttt gctagactca aaggaatgat
    10201 ttggcagttt tctaatccat atgaattttt tttaatcgat tcttgtagcg tttgggtttc
    10261 ctcttctgtt tgggtgataa ctgccgcttt ttctcctttt agagaaacca aaatctcagc
    10321 tagtattttc aacaattctt cagaggatcg aaaagagcgg tattcgggtt cttttccttg
    10381 cggtcggatc gatacgatgt cgatcttctc ttgatccaca gcataggttt tgaaaagctc
    10441 tgtgattgct ccgctagaac ggtaactatt tctaagatca taccgatgga tcggcagatg
    10501 gtagtcgtcg aaacaacgca taatatcagc aaaagtagtg gaagaattaa agattgcctg
    10561 attctcgtca cctactaaag taaagtgagt ttttggaaat aattcgatca atagacctaa
    10621 ttgtgccagg gtataatctt gtacttcatc aatcaataga tagcgaaatg ctggtacatt
    10681 taccttttca acaagtaaat gacgaatagc taatataatg actgcttcat caacagtacg
    10741 tgtgggttgc caagcataag ctgagccata tcgtttttca taaattcttt caaacaactg
    10801 atgctcatcc acccatgcca tttcttcgat ttgtctggtt atttttcgat attttttttg
    10861 taaaagtttc cttgcataag ctacaatact ttgttccgaa tcatcagaaa tcaatttacc
    10921 gaataattcc aactgcctat cttctgtcaa cgagagtacc tgattctgca cagcaggact
    10981 ttttgcttgt ttcaaaagat gattcttcca ttcgctcatc agtgcctttt tcgttgcttg
    11041 aagcctatcg atcaatttag gatgagcagg aactttctca tatatttttt cgatcgtttt
    11101 tttagaaagg actgtttttc catttttagt aagtccacgg ataaaattcg gatgatctaa
    11161 aaacaaagga tctgattgtt ttagattatc gataaacttt ttgctacgca aacgttctgt
    11221 ctgctccgat acattttctc ccgtgatacg tttgaaataa gcctcttcac cttctatttc
    11281 ctctgctgaa agctgtgaaa ccagctgtat gatggttaga ttcagtggat ttctttcacc
    11341 taatgatggt aggacattcg aaatatagtc gataaaccga tgattaggtg atagaatcag
    11401 caagtcatcg gatgtcatcg tatctcgata taaatagagc agatacgcaa tacgctgcat
    11461 gatagcagag gttttaccac ttcctgctac gccatttacc aagatatttt gacttttcac
    11521 atcccgaatg attgtgtttt gttccgattg gatcgtagca gtgatagcct tcatttcatt
    11581 ggtctcatct tggcctaaga cttctaataa tacgtcatct tgaatagcta cagacgtatc
    11641 aaaaaacttg accaaacgat ctctttccaa aagaaattgt cgtctttctt taataaccgt
    11701 atcgatttta ttttgacgaa ccgtataaga agatggacca atcatgttat tgtaaaaaag
    11761 ttcggcaatt ggtgaacgcc aatcataaac aagattttca tctgcatcat ctgtgaaatt
    11821 tgctgtaccg atataaaagg attcttttgg ctcattatcc agaaagtcta caacgacttt
    11881 tccaaagtag ggacttttca ataaacgttc gatctttgct agctgatttt ctgcgttttt
    11941 ctgtttgata ttcatctgat cgatttctct atttttcatt tcaatcatcg aaaaagtatc
    12001 caggttatct aagtaactgt caaaattcaa tcgaagctcg ccagccattt ctttcaacga
    12061 ctggtttcct tctatttttg ccgtatccat cgattcccgc agttcgtttt ttttatcaat
    12121 tagcttttga tacacgttct tcagatatgc ttcttctaac tgtttttgtg tgttgaccat
    12181 acacattctc ctcttttttt aaagtggtgg aaccgattag tttacctctt ttaagagtcg
    12241 aatgcaagct ttttaacgag tatcatttgt taggatatat cagttcttca ggtcggacag
    12301 tttgatataa agaaaatgca ccatcaaggt tttttacgtg gtagccagac tgcttcaaga
    12361 ttctttccgc tagatagcta cgtaatccgc tatgacagct gacgatatat tcttgttggc
    12421 tgtctaattc atttaatcgg tcccgaagtt cattcaaagg gatatgtttg gcttccttga
    12481 atttgccctt ttccaattct tctgctgttc gcacatctaa taaaattttt ccttttgcta
    12541 gttctgtcgg caattcatgc cattgtacgg tttcactaag cccttctgca atgttcattg
    12601 ctgcatatcc tagcatgttt actggatctt tggctgagcc aaatggcggt gcatacgtca
    12661 attctaattc cggtaaatcg aagatcgtca aatgcccttt gattgctgtt gctaaaatat
    12721 cgatccgttt atccacacct tttgccccaa caccttgtgc accataaatc tcgccagtct
    12781 ctggatggaa gatcaacttc agtaaaatat ctgttgcttc tggataatag cttgcatgat
    12841 cttttcctga tacatgaatg acttcaaaag acagttcgtt ttctttggct gttctttcac
    12901 ttaaaccggt ggatgcggca gtcattccaa acgttcgtat aattgctgtt ccaataccgc
    12961 cttgatttct tcgagaaatt ccggaaatcg tgtccgcaac ttgtctacct tgacgattgg
    13021 ctggtgaagc aagagaaata agtgcatctt ttccagtgat ttgctgtttt acaacgatag
    13081 catcccccac cgcataaata tcaggaatat tcgtttgata acgttcgtct actaggatac
    13141 ccccgcgtat gcctaattcg attccagcgg tcactgctag ctggttatca ggacgaacac
    13201 caatggataa aataactaaa tcagcaggga tggtacgccc atcatccagt cgcaatcgtt
    13261 tcccgtggtc ttcaaatcca gcgacagcat gagaagtaat cacttctact ccttgatgag
    13321 acaattcttt ttctataaaa gctgccattt cttcatccag tgttggaaga atatgtggtg
    13381 cttgttcgat caccatgact tctaaacctc ttctttttag gttttctgcc atttccaatc
    13441 cgatgaatcc tgcaccaacg atcacggcac gctttggctg tttttctaat gcatgcatca
    13501 ctttatcgat atctggtaca tttctaatag aaaaaacatt gtcggcttct gttatccctg
    13561 gaatcgatgg aacaactggt tttgcaccag gagataaaac caatgcatcg tactgttcaa
    13621 tgtgtttttg accctcatgt acgacttcta ccgttttgtt ttcgggaaag atggctgtca
    13681 cttcatgatt tggacgcaca tctaaacaaa aacgagcgga taatgattct ggcgtttgga
    13741 caagaagatt ttcccgttca ctgatttctc ccgaaagata ataaggcaag ccgcaatttg
    13801 caaaagaaac atacggtcct ttttcaaaaa caacgatttc tgcatcttcc attaatcggc
    13861 gaagccgtgt agcagcagac attccacctg ctacacctcc gacaataacg attttcatct
    13921 tatttccctc ctactgttcg atcaaaccat tgattcatgc caccacgtac attcactaca
    13981 tcataaccag atttctttaa ttctttagct gcttgtttac tcctcatccc tgattgacaa
    14041 atcacataga cggtcttttc tttgtctcca tcatatctgt ttatactttg taatggaaca
    14101 tttttagctc cttttatatg cccgccccgg tattctgcag gtgttctaac atcaagtaac
    14161 gctggatttt ccaaaagctt ttcctttaat tctgggactg ttatcgattt tattgattga
    14221 aatagcaaat tcattttctg cacctcattt acatttttat aaatacctca tggggtatat
    14281 taaacaggag ctttattaat atgtcaacca gaatgactct tcattttttt cactactttt
    14341 tatatttgca taaaataccg ataaggggta ttatctaatt ataaaaatag aggagaatgt
    14401 gttatggaga ttgataataa aaatatcctg aaccgtttga aacgtacaga gggacaaatt
    14461 cgtggtatcc aaaaaatgat cgaagacgaa aaagaatgta tggatgtcat cactcaatta
    14521 agcgctgttc gttctagtat tgatcgcgta atgggcatga tcgttgcaga taatctgaaa
    14581 aattgctttg agaaacctga tagtaatcca gaagaacaag cggctaaact agaacaagcg
    14641 atcaagatga ttattaaaaa gtaaaggaat gatttcaatg aaagtcgttt tccatattga
    14701 tgaattagaa aaatggtcag aaacagggaa aaacgtaaaa aacctgataa aagcttctcc
    14761 agaaacgacg attgtcgtat ctgtaaatgg catcgcgatt accggttatc tagactctgc
    14821 caatgcagaa ttcttagatt tgcaaggagt cgtttttcac gcttgcgcca atgctatgcg
    14881 tgctaatcat atttcagaaa gttctttacc tgaacaagta atcgttgtac cagcaggtgt
    14941 ccttgattta gttgaactgc aatcccaagg ttatgcttat atcaagcctt agtcagtaga
    15001 ggttgcgaca gaagtgatca gcttcaagaa atttcggctt atttttcgaa gaagctactt
    15061 ctggaaaacc gtgaatcaaa ggttgtgaaa acgctgtcct gcatcaagta ataagaacag
    15121 ccaaacaaaa atagcttctc atatttttcg tttggttggg cttattaccg cagatgcaag
    15181 cttttgaaca ccgtttaagg aagaggttgt gaaatcagcg gtttgaccta agtattagag
    15241 aaaaaaacgg gaaaatagct cctcatattt tgccgttttt tgagctaata ccgaaggtca
    15301 gctgattgaa caccgtttaa ggaagagatt gtgaaaaagt cgcttagttt cgagtattaa
    15361 gaaaaatttt gtgaaaatgg atttctacat ttttgcataa atttggctta ataccgagaa
    15421 actggctttt gaataccgtt taaggaagag gttgtaaaat cagcggtttg acctgagtat
    15481 tagagaaaca aacggaaaaa tagctgctca tattttgccg ttttttgagc taataccgaa
    15541 ggtcagctga ttgaacaccg tttaccaaga ggttgtgagc ctaccattta actccgaatc
    15601 acaagaaata atttcaaaaa caacttctcc tgtttttggt tcggttggct tattatcgag
    15661 aagtagctac tgggagtcta tttatcaaaa aaaggaatgc gacataggtc acaccccttt
    15721 tttattttct ttgaaacatc tttcggtact cgacagcata caagacaaaa gattgtaaaa
    15781 gaccgtaagt gatgacggca aaaatgactc tcacccacag cgttggtaat tctgggaaaa
    15841 gcagcaaaag gatcatgcca acatagatga cagcagtcgc tactttgcca taccacttcg
    15901 ctccacttaa tttgatattt ttagatagcc cgattaatcc agctacaaac ataaagcctt
    15961 cttttatcaa gaatagacca aacaacagcc aaagccacgg tcgataccat gccatagaca
    16021 aaatcagaaa aagttgtgtc aatttatctg caaacggatc aagcaccttc cctaagtctg
    16081 ttacctgatt atatctccga gcaatgaccc cgtctagata atcagacaaa cctgagacaa
    16141 caatgaccgc tcctgctata taaaatgact gtctcagcac aaaataaaga taaatcggca
    16201 gcaaaaaaat acggaatatc gataaaagat tcggaatcgt ttgtatttct ttacgccagt
    16261 ctgtgcttaa tttcatttta tcgccctacc tcctcagcac tcttttcttt ttattttagc
    16321 ttacacgggg aataaaacca atgatttcac tgtttttatt tttctttaca gacactgata
    16381 ttatgagcta atttgagata atcacttgct gttttcatcg tttactcttc tttcttcctg
    16441 tcgtttgcgc atttctttta ctagtacttt atgagctttt tttgatcctc gctctaggtc
    16501 acgctgccgt ttacgtgttt tataatcgat aaacagactg tctaaatcgt aacctgtcgg
    16561 gtacagatct tctgctgaac gcaccagacg aacacgctga cgaggcacgt ggattatttt
    16621 tttgtctaaa tatacatcaa tcgtatcttc acctatatct tcataaacta acgcttcttt
    16681 ttggtattca ttgacaaata tccgatcacc ttttgcaaag agctgacgtt cttttttatt
    16741 ctccttccta tttgtaactg ctgtcttagg aagaaattct tttttctgtg tccgataggc
    16801 tttttccgcc aagtaacgct ctgcttgatg gatcaatttc atcgacatat ccattttatg
    16861 agcaatccac aaagcttggc tttctcctgt ttcttccaac ccgcaactga tatttaggac
    16921 gaagtgcttc ccgatcgaaa gccatagcag ccggcacaaa atcttcatga tctccggcga
    16981 atttcttgat ttctccataa tgggtcgtgg caatgatcaa tgccccttgc tcatacatag
    17041 attccatgat tgcgatcgct agtgcagccc cttcatttgg ctctgttcca ctgccaatct
    17101 catctaaaag taccaacgta ttccttttta tctttttcaa aatagcagcg atgttttgca
    17161 tatgaccaga aaatgtactc aacgcatttt ctaaattttg gtggtcaccg acatcgacga
    17221 aaatctcatc aaagacagca agctctgtcc cttcttttgc cggaacttgc ataccgaaca
    17281 tcgccatcaa agtcaataaa ccgactgtct tcaacacgac tgttttgcct ccggcatttg
    17341 ctccggtgat aatcaagcct cgatagtctt taccgatttc aacatccaat ggtaccgcat
    17401 gctcaggtaa aaatggatgt ctgccttgct tgataatgat atgttccgat ttattgattc
    17461 taggtgtgct tccattgatt tctcggctaa attttgcccg agcaaagatg atatctaaca
    17521 ccgtgatcgt ttcgatcaat aaatcgatca cttcttcgtt ttctgcgata gcaccagtca
    17581 atgccgccag gacttgatat tcttcactga tttcttcagc ttttaacaac tgatagtgtt
    17641 cattcaattt agaaatcaca gttggttcaa taaaaaccgt cgttctttta tttgattcat
    17701 cgataatcgt tccatctatt ttatttttat agctggcttt gataggaatc gtatagtatt
    17761 cgcctttttg aacaatcatt gcttcttgga tcatttcttt gtttttcgga tgacgcaaga
    17821 atttcagtaa ttttgactgg atttcttttt cgattagttg taattgtttg cgtactttac
    17881 gcaaattacg tgacgcgtcg tcactgactt tattattttt tattttctgg tcaatcaact
    17941 cttctacatt tatcaaatca ggaagatgtt tgctataagc aaacaacaag ggtgtctggt
    18001 attgattctt atcaaaaaac tttgtgatca tccgactgct tctaagaaaa tccgcatatt
    18061 cgatcaaatc ggttggctgc agaatcaacc cttttttgac ttgttctgtc agtgcatcga
    18121 tcctcggcaa ccccataaat ggaacatgct gactgctttc taagatcaag cgtgcttctc
    18181 ttgtttcttc ttgacgatcc aagacagttt gtaggtttgt cgagaccgtc atatcgctga
    18241 ttcgtttttt gctatagttt ccaattgctc ttgcttggat ttcctttttg atccgatcaa
    18301 attgtaattg actaatcatt tcgttgtcca tattctctcc ttttcttgaa gagatacctg
    18361 tcccaaaata aataagggcc tagagataaa taaaaggata gaacacagct taaaaaagtc
    18421 atgtcctatc cttattagaa tacaaagata ttgttttcct gacaggtacc gtttcataag
    18481 cacaccaaat aaactttgtt tattggctat tcgacttact gattagatac cagctacact
    18541 cacaaaacat accccattct tctaggtctt atttattttc cacttaacta tagcaagaca
    18601 cattttggtt gtcaaacttt agtatgtttt atagatttac accattaatg aatagacacc
    18661 taccgcgata attgctccga tcattggacc tgcgattggt acccatgaat atgcccaatc
    18721 tgaagttcct ttattagcta ttggcaatac cgcatgtgct aatcgaggac caaagtcccg
    18781 agcagggttg attgcatatc ctgttggccc tcctaatgaa agaccgatgg ctaagatcaa
    18841 tccacctaca gcgaatacgt tcgttccagg tgcaaattcg ttttgtccaa aagctagcaa
    18901 cccaagaact aatacaaatg taccaattaa ttctgtgatc acatttgctg gataattccg
    18961 tatagcagga cctgttgcaa acgttcctaa aatcgcgctt tcatctttcg ttgcattcca
    19021 atgtggcaaa taagaaagcc aaacaagaat ggcccctgca aaagctccta aaacttgcgc
    19081 aatgatgaaa ggaacgacaa gattccaact aattgcccct gtcatcgcca tagctagaga
    19141 gactgcagga ttcaaatgag ctgggcccat gaatccagaa atatagacag ccattgttac
    19201 agcgagtccc caaccaaatg cgatgacaat ccagccagaa gcctgtgctt tacttttgtt
    19261 taaattcaca gccgcacaca caccatctcc aagcaaaact aggatcagtg tcccaataaa
    19321 ctcccccatg atttgagtca tatcactgtt catttatttc tcccccttta gttcccgcag
    19381 atctgattct gcaatcaatg cttctaaacg tttagtctgt tgcgccttct cctcttctgt
    19441 ccattcaaaa tatccagcaa ttgcatcgat cacaggttgc ttgatctcat caagctgatc
    19501 tcgttcaaac aacagatgat ttgtacgacg aatgagataa tcgcctgggg ccaaaaccat
    19561 ttcttcttct aaaccataac gtaaccgagc tgactcagcg agactcaaac caggataagg
    19621 tgccatttct tttgctaatt caaagatacg tcgggcatta gtcccgtaaa aatcagcgat
    19681 ataagtagca tcttcttcct ctaaaccggc tgctactcct tcttttgcta attctgtcac
    19741 tgtttcttct aatttagttg gatcgaagtt tccacctgaa atctgatatt ttttagagtc
    19801 gatttctttc gtctctattc cgtattcttc ttttaataat tggcgtatca atcgcaaagc
    19861 tccttctgcc atcttacggt aatcggtgat tttcccacca gataaagtca gcaaaccatc
    19921 tggttctctt tctaaagaac tacctctgga aatcgtagaa ggtgcttttt catcacggct
    19981 gttttccaaa tggttcaaca cgtcttctac ttcagcacga gaaactttgt tttccttata
    20041 ttcacttact gtatcgacaa ctttattgaa gctcttgtct gaaatcgatc cattatctcc
    20101 accattgtaa tcagaaccag aattaccaat caacagtgga cgaagtcctg cccagcttgc
    20161 ttcgatatca ttcaatgtga tatttgcttc tggatagcga tgattgatca catccaatag
    20221 ataatctaca tcttcttgtg tgactttcgg atccgtaaaa tctccttggt aatccgtatc
    20281 tgtcgtacca aagtaagtct tgttttctct tggaatagca aaaaccatcc gcccatcttg
    20341 ctttcctgta tcgaagtatg tgggttgcgg tacaggcagt tttttcgcat ctacaactaa
    20401 atggatccct ttagttggac gcattttagg agagactgga cgcgtaaaat tcaagtttcg
    20461 tactttatct acccaaggac cactcgtatt gatcactaat tttgctttga tttcgatcac
    20521 ttcatctgtc agcaggtcac gagctttgac gccaacgatt tgatcgccat catataaaaa
    20581 gccaaccgct ttcattttac ttactagata agccccatct tcggcagcct ttttgatatt
    20641 atcaatcact aaacgggcat cattgttgcg gaaatctaga tagacacccg cgccttttag
    20701 cccttctttt ttcaaaaacg gttctctttc caatacttct tctggtgtca gcgtataatt
    20761 ctcatatttg gttcctgtca catttgccag tttgtcataa aggtccattg ctactttgac
    20821 cgagaacata ttgaaggttg ttgctccttc gccctcatag attggcaaaa gcattggatc
    20881 tggttttggg atgtgtgggg caatactttg tacgactgca cgttcaccaa ctgtgtcagc
    20941 tactacttcc acatcaaatg tcttcagata acgaataccg ccatgaacaa gtttggtcga
    21001 gcgagaggaa gtcccttctg caaaatcctg catttcgatc aatcctgttt tgattcctga
    21061 tgctgctgac tggactgcca caccggcacc agtgattccg ccaccgatga tcaacagatc
    21121 caattcttct tgctgcattt tttgaatgct atcttgtctt gtcttgtttg aaaacatatg
    21181 gatttcctcc ttattcaaat gcttgggtag cttttactgc ttttttccaa ccgttgtaaa
    21241 gtttttctcg gcgctcttcc tccatttgaa cttcaaatag cttgccagct tcataaaatt
    21301 cgcggatctc gtctgtatct ttccaataac cgacagctaa tcctgctaaa aatgctgccc
    21361 ctagcgccgt tgtttccaag ttttctgctc gttggatcgg tacattcaag atatctgttt
    21421 ggaattgcat cagatattca ttgtttgctg caccgccatc tactttcaat acaggaatct
    21481 tgattccagt gtcatcttgc atcgtatcga tgatatctct cacttgataa gcaatcgact
    21541 gtaaagtagc tttaatgata tcttcttttg tcgtaccacg tgtcaagcca aacatagccc
    21601 ctcgtgctgc ctgatcccaa taaggagcac ctagcccaac gaatgcagga acaacataaa
    21661 cctcatcttc gcttgtagag cgtttcgctg cgtcttctga atcgctagct ttttgcaaca
    21721 tttgaagtcc atctctcagc cattgaatcg aagaaccagc cacaaaaata cttccttcta
    21781 aagcatagta aacctttcca tttatgccgt aaccaattgt cgtcaataaa ttatttttgg
    21841 ataattgcgg tttttcaccg gtattcatga caataaatga acctgtacca taagtattct
    21901 tgaccatgcc tggttcgaat gccatttgtc cgaataatgc ggcttgctgg tctcctgcca
    21961 tccctgaaat tggtgcttcg cttccataaa aatgataacc ttgcgtataa ccataaactt
    22021 ctgagttaga agtgactttt ggtaacatca ctcgaggaat atttagtaaa tctaaaatct
    22081 cctgatccca atctagctga tggatattga acaacatcgt ccgactggca ttcgagtaat
    22141 cagtaacatg tgcttgtcca tcggtcagtt tccatactaa ccaagaatcg atcgttccaa
    22201 acatcaattc gcctttttca gctcgttctt gcgcgccttc tacatgatca agaatccagc
    22261 gtatcttcgt tgctgagaaa taggcatcga tcactaaccc tgttttttcg tggaaaaatt
    22321 cttgatagcc ttcatttttt aagttatctg caattccagc tgactgtctg gattgccaaa
    22381 caactgcatg atagattgga cgtcctgtat ctttttccca tattactgtt gtttcacgct
    22441 ggttcgttat gccaatccca gcaatctgat ttggtttgat ccctgattcg atgaacgctc
    22501 cggcaataac tgactgtaca gaattccaga tttcatttgc atcatgttcc acccaacttt
    22561 cttgcgggaa atattgcgtg aactcttttt gagaactgcc gatgtgtctt cctttcttgt
    22621 caaagataat tgctcgtgag ctagttgtac cttggtcaat cgccatgata tacgttgatt
    22681 ctgtcattgt gattccctcc attatatgca aacgctttct ttaactactc ttatcatact
    22741 actgttttaa aaaaagaaac tgtcaaaatt ttattctttt tttctttttt tgacagtttt
    22801 ttattatgaa gctatttttt aatcaattct tttctttttt cagcgtctct attcttcttt
    22861 tcaatcgaat aatgtcgtaa ggtgacgcaa attctgacag ataatattca cactgttttt
    22921 tgtttctctg gcaaaatgtg atcaccaaat catattcttt accttcttca taacttccaa
    22981 tctcaatacc gccgattccc ctcagttctc tgatcagata ttgttgaaaa gcaatacgat
    23041 aaatcggcag actttctaaa tcgattccaa tcactactgg ttttgcaata taaaaatcga
    23101 tcatcaaaag aacattggca tactggatca tcaggtaact aagctcacta tcttcagctc
    23161 ttttcctcgg caattgctgc accgctgttt cctgtaattt cgccagtaac tgtgttaagg
    23221 aatgcccgag cattttctgc tgctgttcca aaagccgatc acgctcatag acttcgatct
    23281 ttccaacaaa gaaaaaccat tcattgttga tctgggaaat ttggtagcct actgcctttt
    23341 cttctttgat tttcaaacga cgaggacgat aatgccataa catcgtttcc cgaatgtaag
    23401 tatctaaaac agcggttggt aactttttgc tccgtgtcaa atcatactga taaaatattt
    23461 cttcgtctac tatcgaaaaa gaaacaaaaa agctgtaaaa catcattgtt tcgtatacat
    23521 tcagttctgc tgctgttcga ctaagatgca tcacgatgat tggatcgatt gcttgataaa
    23581 gccggtccga ctgatagagt aatttctttt ctttcaaagt tgcgtacgta cttttttcat
    23641 tcaatagtct ttttttcgta atcccgagcc agcaagcaat ctgtgcttct gctgatgccg
    23701 taaacgttgt ttctaataca cggtccaatc ctagaatgaa cggtcttttt tctggtgtat
    23761 tttgcaaaaa aagcggtcgc tgatcttccg ggatatattg gaatagttca taataaaaat
    23821 atcgtatctg tagctcttct ccgtataatt gaccgttttt gatttgtaat ccaaattcct
    23881 ctaagagctg gttcaattct ttgatctttc gaaaaacaga agactcactg atattaaacg
    23941 ctgtcgctaa tcgaacgatg gatacttgct gatgttctaa taaatagacg agcatcttaa
    24001 acttcaagct ttcctgcaat aaaaacaata gaattttttc caaacttaca tcttcgtcca
    24061 acacaagcag cgcctgatac tcatttcgct gtacttctac ttttttttcc atcattcggc
    24121 caatcaattc aatatcttcc aaatattgat caaacgaggc ttttgacagt tggacatgct
    24181 ctctcaaacc attgatagag gctgttcccc cttgcagaac aaggtttcgc aaaatcagga
    24241 tctgtaactg ctcttttctt tctaataatg cttcaatctt cataggcagt attcgccacc
    24301 tttgaccaca ccatatctgg cacacggtat tctggctgga aaaatagctc atgttcttct
    24361 aactgttcaa acgtccatcc ttcttctact gcaattgtca gttggtcaag aaggtggaac
    24421 atctcttttt tgctttggag ctgtgctcca agaatctttt tttcagaatc aaatagaaat
    24481 ttgagtttaa ctttgctttg atttattgct gtaagcttgt agtctacgta tcctgtttca
    24541 attttttggg gataaaaaat gctctcttct tctgtcaaac ctacgcttcc taagaaatag
    24601 ccaaaccact gattgccgac tggacgatag gttccctgat cctttgtctg tgagccacta
    24661 attgtcttgc tgacatttcg tgctgtacgg acagcgttat ttactagaga aacatacatt
    24721 ttttcatttg ttggacgaaa agttacttgg atcgcatcgc caatcgcata aacgtctttt
    24781 tgagacgttt gcaagtagtc atctacccag atcgttccat catcattcaa tgttaattgt
    24841 tcttcccaca tctgattgtc gggacgagaa tgattagcca gcaaaacaag atcatagttc
    24901 tcctttcttt tttccgtctc tacaatagcg gtttcatttt cggtcaaaga cacaacttgt
    24961 tcttctaaaa aaagtgaaag cccttgattt ttcatttcct ttactaacgg ttctgtcatt
    25021 tcaggatcta gataacgaaa aagaattgac tttcggcttt cgtaaagatg gatttgtttt
    25081 tttcttgatg ccaacccttc agctatttcg attcctgctt gtcctgcacc aataattgca
    25141 attttctttg cattcatgat cttttgctga agagccgtta cgttttgtat ctttttaact
    25201 gggtgaataa gcgttgattc tgcagaaata tttcgaaact tttgatttga accagtcgct
    25261 agaatcaaac gatcaaaatc caattttttt cctcctgcta aaacgacttt tttttctttc
    25321 aatcctatta ctgtcttttc tgtgtaaaca tggattcgat agcggtcagt cagttcttct
    25381 ttcgtgatcc aagaaagttg tttttcactg gtaacctttc cttttaatat caaattgaac
    25441 ccgctgggaa tccatcctaa cttcgattgc ttttcaatca aatatatttc acttgttggc
    25501 atcaattggc gaagataaat agccgcatga atccctgcaa acgacccgcc gacaattaca
    25561 atgttcatct gcattcctct ttcttataag gtgttctact gctaacttct caatcagaaa
    25621 acacagtatt cataactcgc tttcaacctt atgatacata gcgatgcagc agaatcaacc
    25681 ctctccatca taccgtgttc taggtctgct tctcaataat gtactagtgg acctaattga
    25741 agagtatcat ttctgaagag atgtttcaaa aaatgtactc ttataaaaga aaaaaactcg
    25801 ccttttacgt acctctgtcc aaataggaaa cagaaaagaa cgaaaagacg agttttagcg
    25861 tgtgtaatgt aatagttaga atagacacat catttatttt taattcttta atgcttcaac
    25921 aactgcttcg cctaattgat gagcagattg aggattttgc cctgtaagaa gccgcccatc
    25981 aatttgaacc acttctgaaa aagctgctcc agactgatag tttgctcctt tttctttcaa
    26041 agcatcttct gctaagaatg gtacttcatt cgttgtacca tttgcttcct cttcttcatt
    26101 actgaaccca gtcactgtac gtccagctaa aatagatttt ccagactcat ctgtaactgg
    26161 caacaatcct acaacaccgt gacaaacagc tgagaccagc ccttcatttc gatagatttg
    26221 tgaagcgact ttcccaagat ctattgcttc tggaaaatcc cacattgttc cgtggccacc
    26281 agcataataa accgctgcat aatcatttgc atccacatca tcaggacgta aggtatttcc
    26341 caaggcccga tttctgaaat cttcatcttc ataataggcc caatcgattt catccatatt
    26401 caaaacactt tgcggttcta aaggtacata tccgccttta ggactgacaa aatctgcatc
    26461 gatcccattt tttactaata catcataaaa atgagtcagt tcacttaacc acaaacctgt
    26521 aggacgctcg atcttttcgt acttttctac atttgttaat acgatcaata ctttcatttt
    26581 cccatcctct ttctataaaa attgcgttat tgataacgtg ctttcaagaa attatataat
    26641 gggcttggca aataaagctc tttatatgct ttttcaaaag gtttcgttac aaattcatcc
    26701 tcacggtttt ccaataattt ctctgcccag tcaggatcga cgatcatttg ctgtccaatt
    26761 gctgcaagtt ctgcatattt caatacctgc tctacatctt cgcgattgcg gatcccaccg
    26821 acaccaacta aagggatctt tccttgaatc gtgttatgga ccacttcaag aatcgattta
    26881 tcgttgtatt tatcagaacg agctattcga tcatacatat ttaatgaaac atgcagataa
    26941 tctagttttg actcacgtaa tcgttcaaga agccagatcg tgtcttcaaa acggatacct
    27001 ggtgtttcat attcttctgg tgagaaacga taccctacga tgaatggttt tttagcatat
    27061 tgttcaaccg ctgagaaaac cgttgttaat aattcttcaa taaaacgata acgattttcc
    27121 aagctaccgc cccattgatc ctctcgtcta ttcgaatgcg gagagaaaaa ttgttggatc
    27181 aaatacgtat ttgctccatg caactcgatt ccatcaaatc ctgattcaat cgctctacgt
    27241 gtggctttgc caaatgcttg gattgtttca acgatttctt cttcactcat tgctcgtggt
    27301 gtttccgcat caggacgttt tgctgcaact gcacttgcag atacaggctg ttctccagat
    27361 aaagttgctc gacttgtcat tcgtccaccg tggaaaatct gaataatcgc ttttgcgcct
    27421 tctccttgga ttgctttcgc tagctcactt aatcgaggaa tcatttcatc atgagcgatg
    27481 ctgagttcac ctggccagcc ttttccgata tcttggacat ttgcagcacc agtaataaca
    27541 gcaccaagac ctttagaacg ttgtttataa taagtgatct catcttcggt gatcactcca
    27601 ttgaaaaagc tgagttgtgt cgtcataggc gacagcatca atcggttctt caattgaact
    27661 cctgaaggta aagtaattga ttgatcaaat tgtgacattg tcattcctcc cataattcgc
    27721 tctgattaac ctatcgagaa tcatctatca ttaaaccact cgattagttg tacatgcaac
    27781 taatttgctt aaaaaatttt attttttttg taacttatct gttgcatcat tcattgtctg
    27841 ggctaattct ttacttgctt catttcccaa aactgctttg tatgactgat gaagttcttc
    27901 ccagctacca tcgacttcct tagcaaattg gcgtccttgt tctgtaagat aaactaatga
    27961 caagcgacct tcgctaactg ttttgacgta tcctttatat tctaattttt caacaaaacg
    28021 agcaatcgtt gatggggcgg aatagagcat ttgtgcaata tctttttgtg gtattccatc
    28081 tttttctttt aatatcaata aaataaaacc ataagttggt gccagacctg tccttctaaa
    28141 cgcttcatca gctaatttat tcaacatgcg atctagcttt ttcacgctaa agaaaagaca
    28201 ttcatctaac gctttttcaa ttggcttttc catttcatcc cctccattgg cgtacatatc
    28261 atagtatgat ttttattttt tgtcaaaaaa cacggaataa tgtccgcctc ctctgtctag
    28321 atttgaaaaa aagaagtagc catcttcaaa gaatttcggc ttgttttcga caaaactcct
    28381 tctggaacac cgtgaatcag aggttgtgaa aaagtcgttt agttttgagt atgaagaaaa
    28441 attttgtgaa aatggctttc cacatttttg cataaatttg gcttaatacc gaaaaactgg
    28501 cttttgaaca ccgtttatat cagaggttgt gaaaaagccg tcctgcatca agtaataaga
    28561 acagccaaac aaaaatagtt cctcatattt tgtcgttttt tgagctaatg ccgatggtca
    28621 gctgattgta caccgtttat tgagaggtcg tgagcctgcc gttgaactcc gagtcacaag
    28681 gagcaatttc aaaaaacagc ttctcatgtt ttatgactat ggtgacttgt gatcgaggag
    28741 ttggcaggag aatactgttt attcgtaaag aaggggctgt gacaagactt ttgtcacagt
    28801 cccttatttc cttttattat aggatttcgc catttgattg gatgacttgt ctgtaccaat
    28861 caaatgattt tttctttaac cgtttctttg tgccattccc ttcgtcatct tgatcaacat
    28921 agatatatcc ataacgtttt gacatttgtg aagtagaagc gctgacgata tcaatgcagc
    28981 cccacgacgt ataaccaaat aaatctactc catctttgat agcttccttc atctgctcaa
    29041 tatgctgctt caaatagtca atgcggtaat cgtcttgaac ggttccatct tcttctactt
    29101 tgtctatagc tccgagtccg ttttcagcta tgaacagtgg tttttgatac ctatcatata
    29161 attgattcaa agcaattctc aaacccttag gatcaatctg ccagccccat tcacttgatg
    29221 gaagatacgg atttttaatt cctccagtta ttaagtttcc ttggacccct tcccaatttt
    29281 ctggatgagc actgactgca ctagacatgt agtagctaaa agaaacaaaa tcaacagggt
    29341 aggctgctaa gatttcttca tcacctactt ctatttttaa gttgacacct ttttcttcaa
    29401 acattcgttg cgtatacgct ggataatatc ctcttgcttg aacatcacta aagaacaaag
    29461 aagttctttg ctgctcaatt gttttttgaa tatcatccgg atcacaagaa tacggaacaa
    29521 gaagctgata gctgatcata caaccgactt gtgaaccttt gataatttca tgacaagctt
    29581 ttgtagctaa agcacttgct ataaactgat ggtgtgcacc ttggtatttc gcttgttcca
    29641 aatggggatg gttttcttca attactccta cgctaacaaa agggtgatgt tttacacagt
    29701 tgatctcatt gaaagtcatc caatatttta ctttattttt atagcgtttg aatactgttt
    29761 cagcgaaacg aacgtaaaac tgaataagct ttcgattagg ccatccacca tattctgtaa
    29821 ccaaatataa cggcatttca taatgggaaa gagaaacgac tggctcaatc ccatatttta
    29881 gacattcgtc aaacacttga tcataaaaaa ataatcccgc ttcattgggt gtttcttcat
    29941 caccatgagg aaaaattctt gtccatgcga tagacatccg atagcattta aaacccattt
    30001 cagcaaataa acggatgtct tctttaaagt gatgatagaa atcatttccg tgtcttttag
    30061 gataataata cttgctgttg ggatcctgcg ccgcttttac ttgctgatgc gtcatcatat
    30121 gccattgatc tgtccatttt tctttaggta aatcgctgtc gaatgtatac acatcagaca
    30181 cagataatcc tttttcatct acatcccatg caccttcaca ttgattggcc gctgtcgctc
    30241 cgccccataa aaatccttct ggaaattttt tcatatcgat ccccctaaac ttgctagttt
    30301 tcttgtttga ttatttttct tatgactagt aatgatattt ttgaatctac tactatttgt
    30361 aacaataacc attgtggtcg gatcatatcc ctctttgatt aattcttgca aatctacttc
    30421 catcaataaa tcgcctttac gtactttttt tccatcagat actgcacttt gaaagtattt
    30481 gccatttaaa ttcactgtat caataccgat atggatcagt atctctgctc cttcttcact
    30541 gactacccca attgcatgtt tcgttggaaa aactgttgaa acttccccgt ttacagaact
    30601 gtagattttt ccgtccgttg gaatgatcgc aaacccttct cctaaagatc cactagcaaa
    30661 tgttggatcg tttacttcag ataaatcaat tatttcacct gctgcaggag tacttaacac
    30721 tatatccttt gaggattctt cttcgatttc atccttgtag ccgaaaagaa aagttagcat
    30781 acaggaactg atcatcgcta agaaataact agcaactagc caaacaaatc cttcaccaat
    30841 ataaatcggg aaagacaaaa tacttcttgt agcaactgcc aaagcaccgg ctcctgcggc
    30901 accagctact ccaccaaata tagctccaca tatacaagca atgtaaaatg gtcgtttata
    30961 tttaagagtc acaccataaa cagcaggttc agtgattcca aataatgctg tgataaatgc
    31021 agataaagat aaacttttta ctttcttatt tttcgttttc aaaaataccc caagtactgc
    31081 tcctgcttgc gcagctacgg cagtcataca tgctggacct agcgtatcac gaccgtagaa
    31141 agaaagattg ttggtcatta ctggtacaag tccccaatgt aacccaaaaa tcactaacac
    31201 ttgccaaaat ccgccgataa cagcaccaga taaaacaggg ctaaagttat aaacagctaa
    31261 atatccagct gcaatcagct gacttgcata atctgcaatt ggacctacaa ctaataaaat
    31321 aattgggacc atcacgatga tacaaatgaa tggtgtcaat aaatttcgaa tactttcgtg
    31381 caagcttttg cgaatcttag gctcaatata agaaagaacc catacagcta aaattgctgg
    31441 aataaccgta cttgtatacc ttgctagaat cacgggcatc cctagaaatc gcaaggttat
    31501 gctatcacta tatgcactga caatcgtagg ataaacgaga gctgctgcaa taaccatagc
    31561 gatgaaacga tctgtattga acttttttgc agcagtatat gccaaaaata taggcaagaa
    31621 atagaaaaat gcatcagctg ctgcattcaa aatgatataa gttcctgatt cagtagttaa
    31681 taaattcaaa ctcgtacata aggcgagtac tcctttgatc aaaccacttc ctgccaagac
    31741 gcctaaagtc ggggcaaaaa cagcggcgat catgtctata aaagagttta aaatgccttt
    31801 tttctcagtt cctctctttc cactagatgc atcatcttct agtttcattt gtttggataa
    31861 tacgtcatac acttcattta ctgcatttcc tactacgact tgaaacattc ctccagcttc
    31921 gactacagtg atcacacctt ctagttgctc taccttctcc ttatctgcct tcttattatc
    31981 ttttagggta aagcgtaacc ttgttgcaca atggtaaaca ttgctgacat tttcttcgcc
    32041 tccgacaaat cggacaatat ctttcgctaa ttgtgaatag tccattttta cttccccctt
    32101 gttaattaat gccgtagcaa tccttcttac aagataagta tagttcttag aaaacggttt
    32161 ctccattcaa ttagtacccc ttctaatagc gaacgaaact gtacaatagt gtgtatggtt
    32221 tacttagccg agcaaatcac tcactgcttg aaagaaaaca agtatatcgt ttctcttata
    32281 gtcaaaggag acaaaaaaaa cacgcttgat cttcctttgc tgatgtataa gtggtatctc
    32341 aagctgatac tctgtgattt ttgtttctac ttggcttttg ataagacagc acaacaaagt
    32401 ctcggcattt aacggaagca taactaggtc agaactagga gagattagtt gctgaatgga
    32461 atctatcttt ttatggattt ttatttgatt ttcttctttg tagtaatgat caagcagttt
    32521 tgttttcttt ttttcttcaa ctatggtcag cttttcacgc aaaatctgat aaatctccca
    32581 agattcaaac tcatctagaa cactaggtag ataaatcaaa tcatcccact caaaaataag
    32641 ctcttgctca gtagtcaaaa ttgcatcata ttccgttatt ttgtttgatt gatttttgaa
    32701 aagatacact ggttctatcc ggcattcttt gatccacatg ttcatacttt gttgaatctg
    32761 tttttttagt gtattcaaaa tactaattgg ctggttacta acaatcagta tctccccttg
    32821 ttttcgaaaa ggattcaacg cttcggcaag atacaaaaca aaataagcgc tttcagctaa
    32881 attgggacgt aattgaaaat gtattgggaa gaaacgccga attaaataaa tttctaaagg
    32941 ataacgggag atgatctttt gtacaaaatg attcatggta ttatgtccgg catccatcct
    33001 cgttttcatt tgtttgatat gggttagcaa aaattctgtt tcatggaaca ataacgaaac
    33061 aggaagatct aaaaaacgaa taatcgtttg ctcaaatgct cttagattct tctctatttc
    33121 tttgtttttt tcatcattaa tcatcaaata atttaactct aatagtcgat tttcaattgc
    33181 ttgtttttct tgattggaaa aagaataggg tagttctgat gataactttt ttgtgagggt
    33241 ctctaccatc ggaataaata atgtatacct gtttgttttt tctaaaagtt cttctcttcg
    33301 aagaatggtc aaaacgagat accgagaaaa tcgtatgaag tcctctcctg aaacaatata
    33361 attatatgat ataagaacct cttttaatgt cttttggaca gtcggcatga tattggaaaa
    33421 aattgtactg atttgttgag gaaaccttgc gtgttggatc accgtttctg ttccaacaag
    33481 agataagaaa attctttttg aattttcttc agcaatgatt tttagtcctt ttgtcgacga
    33541 aacttccagt tctaatttag gattgcgctc gatccaacgc aaaatcgttt ttatttgtaa
    33601 tgatacggct gtttttgaaa gaaagaaaat gtctgctatc ttttgcatac tgacataccc
    33661 tttttgaaac aataagtacg tcacaatagt tgaagctcgg aaatccatgc tggaatagat
    33721 tttatgtttc gtcacctctt gtatgatttg ctgtttagtt tcagattcaa ttgattctaa
    33781 aaaataacct gaacgtttat ttgactggat aatgattttc ttctcgtaga tagcaagcat
    33841 atttttgatt tcagtttgga tcgttttctt gttggtacct aaagcttcag ctaattcttc
    33901 gcttgttatc caatgattct tatttcttaa tactacaaga atttggagtt gtcgtttatt
    33961 taagtccatt tgcttacacc tcctctttgt tataaacata caggaaaaac ctctcaaatg
    34021 acaatagtca cttgcagagg tttaaaaatc atttgaagaa agatctatat tcaaggtttt
    34081 taccattaga ctggataatt tgtttataat attcaaaact atcttttttc aatctcctaa
    34141 agcttccgct cccatcattt tgtctatcca cataaataaa gccatatcgc ttcctcattt
    34201 cccctgttcc tgccgatacg atatcgattg gtccccacca taagtaacca atgatttggc
    34261 aaccatcttt tattgcctca gcaatttcct gaagatgtat ttttagatac tcacaacgtt
    34321 ttggatcgtg gattcgattc aattcatctg gtgcttcatc tagtccaatg ccattttcaa
    34381 ctatgaataa tggtaattca taacggtctg tcaattcatt catgacataa cgaaacccta
    34441 gaggatcaat tggccaactc caaggttcgg gagatttttc cttcaaaaag ggattatcga
    34501 aaccatttgc tccgccagta tctacgcgca tttctgcttc ttttttatag acagcgctac
    34561 gataataact aaatgcaata taatctgccg tgttagcttg caagcactgt tcgtctccat
    34621 ctaacattac tggtgcacag tcttcttcct tccatgtcct gtaaatataa gctggataat
    34681 gccctcggca catgacatcg gagaaaaacc atgaattgcg tttaaattgc agtgaaccaa
    34741 atacattctc tggatcacag tcatatgcat aagtcgctaa tgcagaaaag ctacacataa
    34801 tacccatctt agcatttgga tcgattttct ttaataattg agtagcacgg gcgttcgcta
    34861 gaaacatatg atgacaggct tgataaatca ctttttttgt tagtgtagca atgggttcaa
    34921 gtttatctct agcagggaat gtaaccaatc cagcagctgc ataaggcata cgaaaagcat
    34981 tattgatctc attaaaggtc atccaatatt tcactttccc ttggtagcgt tcaaagacgg
    35041 tctgcgcata aaattcaaaa aagtcgatta attttcgatt ttgccacccc ccatactctc
    35101 ctaccaatgc taagggggtt tcataatgac taagagtaat tactggctcg atatcatatc
    35161 gatttaatgt attgattagt ctgtcataaa atacgagacc agcctcattt ggcttctgtt
    35221 cgtctcctct tggaaatatt cgtgcccatg agatgcttgt tcgaaaagct tttaaaccta
    35281 actccttcag taaacgaata tcctcttcaa atcgatgata aaaatcaatc gcttcatgag
    35341 aaagataatg gagtgattcg tctaaagcaa tctcccaaat ctttttttct tcattccact
    35401 gaatactagg atgctggttc atgatcccga taagcgtatc tgtcacatta ggtaatttgc
    35461 cgtcttccaa ccatgcacct tcacattgat tagcagctac tgctccgccc cataaaaaat
    35521 tttctggaaa tatttcctga tccataacta tctctcctcg ctatcaacaa tttcttactt
    35581 gaagtatagc tcgattcatc aaaacaagat attctaacta tttcggcaga agagaagaaa
    35641 aaaattgaat gctactcttc atttttaata tttatatata acaaatacat aagacgatcc
    35701 ccgaaagaaa acactcgtta accatctaag caaacgattt attttacttc caacacaaat
    35761 gcttcataag gtcgtaaatc aactttgccg tctggtaact gtttcagagg ataatttgac
    35821 acaataaccc ttaaagcttc acgtggaata gtgaacgtct gcttttcact ggacatatta
    35881 caaataacga gccattgctg gtcttcatat atgcgagaat aggcaaagac atgctcaggc
    35941 gtcttttcca ctaattcata gtctccccag acgatgatgt catgttttct acgcaaatcg
    36001 atcaatttct tgtacatata aaaaacagaa tcttgatctg ctaacgcttc ttctgcattg
    36061 atttctttat aatttggatt gactcgaagc catggaattc cagtagtaaa cccagcatgt
    36121 tcacgggcgt tccattgcat aggcgtccta gcattgtctc ttcctttcgc cttgattgat
    36181 tccaagattt cctcttttgt aaatccagaa gaaatccttt cgttatacat attgattgtc
    36241 tcaatatctt ttgcttccgc gatatcatcg attgggcaat tcgtcatgcc taactcttct
    36301 ccttgataga tataaggggt gcctttcatc atatggagca agatagcaaa catcttggca
    36361 ctttcttttc gatacacatc gtcatttccc caacgagaaa caattcgcgg aagatcgtga
    36421 ttattccaaa ataaactatt ccatccttca tcacctaaag atgtttgcca tttggataat
    36481 acttttttca gttcagagat actcaagggt ttcaaatccc atttgtcttt gccttcttgc
    36541 tgatctaatc ctatgtgttc gaattggaag accatggata attcatttct tttaggattg
    36601 gaataaagtt tagcgatttc ggtagttgct ccccatgttt cgccaacagt catcagattt
    36661 ttgtcaccaa aagttgcttg attcatttcc tgaagatact catgcagttt aggtccatta
    36721 cttgtgattt ctttatccgg ttctttgcca atcatatcga tcacgtccat acgaaagccc
    36781 ccaatacctt tatcgatcca gaaattcatc atttgataaa tctcttggcg aacctgttta
    36841 tttttccaat tcaaatcagg ttgacgcttg ctatacaagt gcagaaaata ttgccccgtt
    36901 ttttcatcca actgccaagc agaaccactg aatattgagc gcaatctatt aggctctttt
    36961 ccattgaccg gatcacgcca aatataatag tcccgataag gattttcttt atttttacgg
    37021 gcctcaatga accacggatg ttcatcagaa gtatgattca ccaccagatc catgatgata
    37081 cggatatttc ttttctttgc ttcttcaatc agttcttcca tttcttccat cgtaccgaat
    37141 tctgccatga ttgcttgata attactgata tcatacccat tgtcatcatt cggagactcg
    37201 tatactggag aaagccaaat tgcatcaata cctaaatacg ccagataatc caacctggaa
    37261 ataatccccc gcaaatctcc aataccatct tgatttgaat cttgaaaact tcttggatag
    37321 atttgataaa caactgaatg gtgccaccat ttttgttcca tgattttcct cctataaatg
    37381 gatgtttcta ttttttgctt aatcatttat tttagtctct ctcactaaaa attgtaacgc
    37441 tttcaaatag ctattgcacc ttgttatcgg taacagaata aaacaaaaaa acagctgagg
    37501 aaattccctc aactgttttt tgaaaggatt gatttatgca gggaagaatg ctgatttcac
    37561 aacttcttta taaacggtgt tcactcagct gtcccttggt attagctcaa aaaacggcaa
    37621 aatataagaa actatttttt cgtttttttc tctaatactc aggccagaac gctgatttca
    37681 caacctcttt atttcacatt caatatccac atgaatccca caaatacaaa gaacagacca
    37741 tacatgattg gagatacttc ttttcctctt ttagctgcta acatggtaat tggatagaag
    37801 ataaaaccta atgcaatccc atctgaaata ctataagtca aaggcatgcc gatcaagatc
    37861 aagaatgaag ggatcgcaat ctctaagttt ccccattcga tttgtcgcaa agattgtgcc
    37921 atcaatactc ctaccataat caatgctggt gcagttactt gtgaagtaac aactgatagt
    37981 aatggagaaa agaacaagcc taacaagaag aaaatccctg tagtaatagc tgtgatacct
    38041 gaacgtcctc caacggcgat accagctgat gattctacaa atgcaccaac aggagaagta
    38101 ccaaataagg aacccgcaag catagctgtt gaatcagaag ctaaagcttt ccctacacga
    38161 ggcatcttgt tgtctttcat gaaacctgct tggtttgcta atccaactaa agttcctgct
    38221 gtatcaaaga aagtcacaag caagaatgtc agcactacga cccacatttg aagagaattg
    38281 atgtccccta catgttttaa tgcaactaaa aatgttggtt tcaaacttgg tgctgcggca
    38341 acaatttcag aaggcattgg aatcaaacct gtgaccagac ctaaaatcgt tgtagctgcc
    38401 atcccgatga agatgccacc tggtacacgc cgaacaagca agatagcagt tacgactaat
    38461 ccaaaaatcg tcaaccaagt agaaccaacg ttgagtgatc ctaatcctac taatgtagat
    38521 tcattcgaaa cgatgatccc accttcgctc agaccaagga aagcgataaa tagaccgata
    38581 ccgccagaaa tcgcatattt caaatctgct gggatcgcat caatgatcat ttcccgcagc
    38641 ttgaagattg tgatcaaaat aaaaatcaaa gaagcaacga atacgccggc taatgctgtt
    38701 tcccatggaa tccccattcc taaacaaaca gaataagcaa aaaaagcatt gatcccaaga
    38761 gcaggtgccg ttccaattgg ataacgggct aataccccca ttaaaacaca gccgatcgca
    38821 ctggctaatg cagtcgcagt aaacactgct ccttcatcca ttccagaagc acctaataca
    38881 gttggattta caaataagat ataagccatt gagataaatg ttgtaaatcc tgccagtacc
    38941 tcacgtttta ccgtggtgtt caatttttct atttcgaagt aggaaagtat tttttccttc
    39001 atcttccatc cccctaaatc cgaacattat aaataaagtc cgttaaaatt tcgatttatt
    39061 aataaaacaa cgtgttttat catatactaa aacaaaacat aagtaaacaa aaaattcgga
    39121 ttttaagcaa aatccgaacg ttccatctga ttaaatccct ttatctcaaa gttcatgaac
    39181 attcactttg gattacaaga atttctttat tgtgttaata aagtttcttc attctagtct
    39241 caaaaatcaa tagtgtgatt tgattttacc atttcgtttc tgttcttctt tgatgaattc
    39301 ttttgtatcg acaggattca gattatttag tccgccaaaa cctgtatcga ccatttttcc
    39361 ccagcctttt gtcttctttt ttcctgattt gagattcttt gctcgaagct tctcactatg
    39421 ttttgctcgc cgatacttca aataaccttc taatcttccc attagatcca ctgtttttcc
    39481 tcctttttat tcaatcagac gactcagctt ttcctataac aaaataattg ccttcagggt
    39541 cagaaaaatt gaaagtcaag atgccattgt tatctgtgat ttctcctggt tcttccatgt
    39601 tctcgtagat agtttcaaat tcatccgtaa aaaatactaa agaaggcggt ggtcctaata
    39661 cctctggtga aaacttctgc acaaatactt ttgggaatac gcctaattct aattcttttg
    39721 agatgctgag tacaatactc ttaaattctt ctggcaattc gattgtttca gaaatttctg
    39781 caccaatttt ttctacaaag aatcggcaaa tcatctctac gtcattgaca taaagcatca
    39841 cacgtgtttt ttgtatcatc atttgaccct tctttctatt tgattttctt tcctgtctat
    39901 aaactgattc cattatatca cgaaagcgca aacaccttgt gtttgatact attcaagaaa
    39961 aataaagcaa tagtttctag gattgctttc ctccacaaac tttttttaca aaaaaaaaac
    40021 ggcaatgaat gccgctcttc ttatttcgat tcttttataa ttctgcttct gattcatctt
    40081 tggttagtgt gtgtctaaca ctagttacgc caaatgtttg atcgattttt tccttcaacg
    40141 cttcgattgc ctgtgcgcca cgtgccgctt gttcagcatt gatggattca atgaccagca
    40201 ccgctgcttg tgtttcttcc gtcagcatcg ttctttgggc ttcacgccag ttgagacagc
    40261 gacagatcgc tccttgttca tcatagtaga tgatttcttc cggaagtgcc ggagcatcgg
    40321 aatctgcacc taaaggcagg aatgattcgc caccttgggc ttttcctaaa tgcagatttc
    40381 ctgcgatctt ttcgatatct tctccgccgc aaggtacgcc aaaagacaag gaaatactat
    40441 tatagatatc tacaagcgga ttgattggga aaaattcccg ttcttgattt gcacgtttca
    40501 gtaaagcttc aatagaagaa cgtgcacctt ttttagtctt gaatgtggta aatgcctgac
    40561 gccactgagc aatgacttcg ttttggctga atgtttcttc tgtaaggtaa tttcttgctt
    40621 cttttgctgc ctcattcaat aattgatgat acgtttcttc actttctttt gttacgtggt
    40681 tatcgatacc atttacggat aagatttcga tggttgcttc aggaaatact tcccagaaat
    40741 tggtatccac tattactttt ttcatctgtt cacacctctt gattagaata attgcttgat
    40801 gaatagatag tctgtttggg gatcatctcc catataaaaa acatgttcgc tgtatttgat
    40861 aaatcctttt ttacgataaa aagcgagcgc aacatcgttg tgttcccaaa caccgagcca
    40921 aatggctgtt ttttgctttt cttttgcttt ttcaatagct gtatctagta aaaatgtacc
    40981 gataccttga tgtttaaatt tttttcgtac atagattcgc tcgatttcta aaaaatgatc
    41041 agccatttcc tcagattgac tcgttcctgt atttagtttc aggtaacccg caggctcttg
    41101 atcgatactc actaggaaaa aatcggtttc tttatctttt agctcttctg taagtttttc
    41161 tagtgcataa gcttgtgtca agtaatcagc taaatgctcc ggtgaattat cttttccaaa
    41221 tgtatctgta aatgtttcga tactaatttg ttgtagtaag tctacatctg aaggcgtcat
    41281 ttttcgaatt tcgtatttat tcacggcttc ttcctttcaa tagatccttt tattgccttt
    41341 tttgacaaaa ttccaatctt cgctaacatt cttgcatact ttatttaaaa gatattccaa
    41401 ttgttttgct tcttcgtcag aaagaccatt taatgcgact gcattggagt agttgttttc
    41461 tcgaatgatg aaaggataga tttctgctcc ttttttagtc ggatagagtt tcttgatttt
    41521 tttattttct ttatcttcca aacgttcgat catcccattg gattctaatt tcttgattgc
    41581 tcgggcagtc gttgtacgat ctactttgat catttctgct agtttttctt ggatgattcc
    41641 aggattttcg caaatacgta ctaaataaag atactgtcct cttgttaaat cgacttcttt
    41701 gaattcgata ttgctaatag aatctagcgc tcgggcaatc attccgatgt ctcgaaggat
    41761 ttcagccatt tcatcccacc tttattttgt ttgtaagact agttcacctc tttttgttgc
    41821 aaatgcaact attttcaata aaaaaatcaa gttctttttt aataactagt aaagtatatt
    41881 cttttcttct tttacgaaaa agctcaatca caatagatct ggtttttgtt ttctaaaata
    41941 agtaactgtt tcttcgttgt tcgcttttct gatagctttg gcaactcttc tatactaaaa
    42001 aatcccatgt tggaagtttc attattctca ataaacttgg cctcttcacc gtggatcgca
    42061 caagcaaaaa caagtttata atactgaaaa agctgtggaa tatctttttg tttattcgta
    42121 tcaaaaactg ctcgcaactg agtagtttct actgttaatc ctgtttcttc atagacttct
    42181 ttacgcacat tttcttcagg agacaatcct atttcagcaa atccaccagg aagtgaccat
    42241 tctttcgtcc gtttatcttc gattagtagg accttgccat cttttttgat ataggcacga
    42301 acatctactt ttggtgttgg atgtccttct ccaatcgttg tgagcgcttt tatttcttcg
    42361 aaagtttctt ttcctatttc actgatcagt tccaatgaaa tcgtccggat ctcctcaaaa
    42421 cgctctttat caaatacatc ttttccataa tatagaccag cttgagaaag tgcgagtagt
    42481 cttttgtatt gagccaactt cttgttcatt ctcttccctt cttttttagc aaatgtatga
    42541 ctatgtaatc aagtatagaa gactggttta attacggcaa ataaatataa tgaaatctgc
    42601 aataaataaa agaatgttaa aaaactcgag aacaaaagac attcgacttc tctggggctg
    42661 tgaataaatg gcgttcaaaa gcttgcatct gcggtaataa gccccaccaa acgaaaaata
    42721 tgacgagcta ttcttgtctg gctgttctta ttaattgagg caggacagct ttttcacaac
    42781 ctccccacta aacggtgttc tcctaccaac tcctcggtca caagtcacaa tattcatcaa
    42841 acatgagaag ctgttttttt gaaattgctc cttgtgactc ggagctgaac gacaggctca
    42901 cgacctctcg gtaaacagcg ttcaaaagcc aatttttcga tattaagcca tttctttgtt
    42961 acttattgtc attgatttct ttttctaatt tatccaatag tggagtgtaa tccacttgag
    43021 tatagtctgt tacatcaaat tcatatagtg ttcctaactg gaatttgtca tattttcggt
    43081 cggcgatgat ctttttgaat gcttctttcg taatatgatt ggtccctttc gttcgatctt
    43141 ccaatacgtc accatagtga taatgatcca tgatatagct caaatgacga tctgattcac
    43201 gatcacgttt gtaccgacgt tgccataaca cttcaaagtc tgctgttagg cgaatcgtga
    43261 tcacctgata tccgtatcta tctgctaatt cttggagtcg tgctttttgc ttatcactaa
    43321 aaggatactc ggacacaatc actttctttc ctgcttccat atacaaatca agtgctttgt
    43381 aatagaaagg ataaactttc gtcctttctt gttccgcccg ttcttccaaa ttgttaaacc
    43441 cgatggattc tgcatagtat tccttgattt catcgagcgt gatggcatac atatctggaa
    43501 atcgttcccg tagtttattc ataagatatg tttttcctgt accaggacta ccagccagaa
    43561 gaatgaaata ctttttcatc tcatttattt cctaagttaa ttggactttc caagttcata
    43621 aacagtccaa tcttatgctt gacaatttct tttactgctt catttgctgg aatcacatta
    43681 tggcgaagag acttgttgat ttctgtttca ctaaaggttt ctttagctac tttcgtccag
    43741 ttgactaaaa gctccgttcc aacattgaat ttgcggatcc cgttattgat caattcagga
    43801 taatcttctt ctttcacacc tgttcctcca tggataacta gggggacatc aactactgca
    43861 tcgatttctt tcagcaaggg aatgtttact tctgtttttg atttgaattg tccatgattc
    43921 gtaccgatag caatagctaa tgcatccacg cctgtagctt ctacaaattt cactgcgtct
    43981 tccggtcttg tatatacctt gtcattttca gcgacatgga ttccttcttc tgtaccgccg
    44041 attgttccaa gttctccttc tacggaaaca ccgtgcgcat gggcatattc tactactgct
    44101 tttgtcttca ggatattttc tttgaaaggc agatgggacc catcatacat gacagaagta
    44161 tatccgctgt cgattgcttc tttgatatca tcaaagtctc gggcgtggtc taagtgcaag
    44221 actgcatcaa ccatttcttc ttctgcaata gctgtcatta cattgactaa cacatgcatg
    44281 ccgatatatt tagcggtatc gacacttgtt tgaataatga tcggcgaacc catttctttt
    44341 gctgcgccta gcatagcagg aagcatttct aggttatgcg tattaaaagc tccaactgta
    44401 aaattcaact cttctgctgt ttttgttact tctttcaatg ttgtatacat cttttattgc
    44461 caccttatct ttttatttgt ttcctttgat cgttacttgt tttgcaattt gtcgcatctc
    44521 atccattttg cccatgtagt aatcgatccc ttgatcatca ccagcacgag cagcatctgc
    44581 acgcttctgg ttatagaggc tcatcagttt tttataccca tctccgatcg tctgtttatt
    44641 ttccaaactc ttttctaaat attggatggc ttgatcgttc acatacaatt cagaaaattt
    44701 aagtccaact tgttcataaa gtttcgctaa tttatgctta tcttgggtag tggaaatctc
    44761 ttgtttcaat tgtgtaatct ctgattgaat cttttcggtc gcttctggcg atagggcttt
    44821 ttcttctttt gccagaactt ttttcggttc tttttctttt ttcttaaaaa atccaaacat
    44881 cattttccct actttcaatt aaaatgcttt caaaactggg cttaagatcc aggcatataa
    44941 gagtgctgcg gctactgtat ctacatcggt tgctgtagca ttgttgaatc ccatcgaatt
    45001 aaagatcgtt actagcaaag cgggcaataa tgtaataaag aaaccatgag caataccgcc
    45061 aatgatcgct cctcggcgtc cgccaactgc gttgccaaat atccctgctg tccctccggc
    45121 aaagaaattg gttagcatac caggtaaaat catcgctaag ccgaacatgg gcaaagtaaa
    45181 catggcaata atcgtaccaa tcgttgtcgt aatgaaacct aaaatgacag catttgggct
    45241 ataaggaaag aaaactggac aatctaaggc agggatcgca tcaggaacta atttcatagc
    45301 tatccctcga aatgccggca cgatttcacc taacagtaga cgtacaccag ctagcaatac
    45361 atacacaccc actacgaatt ggatggcttg taaaaaggca aacatgatat agttttgatc
    45421 tcctgataat tcagaagcga atggttcgcc tgcaaataaa acagtgatga tatatagcgg
    45481 gaccatcacg accatgacag acaaataagt atcttgcaga aattcgaaat gtgtcggcaa
    45541 cttgatatct tcgatcgact ttttattttc gcctttctca ccaaaaagct tagcaacacc
    45601 ggcttcaaat aagtacccga tcgtacaaaa atgacctaaa gcaatatcat ttgatccagt
    45661 gattttacga atgatcggtt gcgctactgc cggcatagca atggcgaaac aagctccgat
    45721 aaaaccaccg accaagatca atacgatccc tcgcagaccg gcaaaatagc caaagactgt
    45781 cgtcatcgtt gccatccata aaattgcttg accagttaaa aaaatgtact tccattttgt
    45841 gaaacgagcc aaaataatat tgaatacaaa aatggctaag aacgtcagtg caatatctct
    45901 acctaaaccc aaatcattca ttgcttgacc attgatagat tcaatagaag ggatgatccc
    45961 ttgcatatga aatccttcag taaagatttt cccgaaataa gttaaacttc caacgatgat
    46021 gctcgaaccg gcactcaaca cttgaaatcc taggagtgtc tttaacgtgc cagagatgac
    46081 ttgtcctgct gatttcttct gcagtagtag acccaacata gcaatcaatg caatggtgat
    46141 cgatgcctga gtcaaaatat tttcgatgat aaaattgata acgcccatgt t
//
LOCUS       DAZKCW010000022        45267 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000022 DAZKCW010000000
VERSION     DAZKCW010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.022"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(129..1895)
                     /locus_tag="ACG84Z_001280"
     CDS             complement(129..1895)
                     /locus_tag="ACG84Z_001280"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162132.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(1855..3609)
                     /locus_tag="ACG84Z_001281"
     CDS             complement(1855..3609)
                     /locus_tag="ACG84Z_001281"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162133.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3719..4288)
                     /locus_tag="ACG84Z_001282"
     CDS             complement(3719..4288)
                     /locus_tag="ACG84Z_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFP9162134.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(4306..5721)
                     /locus_tag="ACG84Z_001283"
     CDS             complement(4306..5721)
                     /locus_tag="ACG84Z_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162135.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(5732..6400)
                     /locus_tag="ACG84Z_001284"
     CDS             complement(5732..6400)
                     /locus_tag="ACG84Z_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFP9162136.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(6530..7114)
                     /locus_tag="ACG84Z_001285"
     CDS             complement(6530..7114)
                     /locus_tag="ACG84Z_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9162137.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(7445..7678)
                     /locus_tag="ACG84Z_001286"
     CDS             complement(7445..7678)
                     /locus_tag="ACG84Z_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFP9162138.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(7693..8643)
                     /locus_tag="ACG84Z_001287"
     CDS             complement(7693..8643)
                     /locus_tag="ACG84Z_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFP9162139.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(8640..9482)
                     /locus_tag="ACG84Z_001288"
     CDS             complement(8640..9482)
                     /locus_tag="ACG84Z_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFP9162140.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(9484..10203)
                     /locus_tag="ACG84Z_001289"
     CDS             complement(9484..10203)
                     /locus_tag="ACG84Z_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFP9162141.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            10751..11053
                     /locus_tag="ACG84Z_001290"
     CDS             10751..11053
                     /locus_tag="ACG84Z_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162142.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNTFKIT"
     gene            11125..12351
                     /locus_tag="ACG84Z_001291"
     CDS             11125..12351
                     /locus_tag="ACG84Z_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9162143.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(12439..12831)
                     /gene="rpsI"
                     /locus_tag="ACG84Z_001292"
     CDS             complement(12439..12831)
                     /gene="rpsI"
                     /locus_tag="ACG84Z_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFP9162144.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(12847..13275)
                     /gene="rplM"
                     /locus_tag="ACG84Z_001293"
     CDS             complement(12847..13275)
                     /gene="rplM"
                     /locus_tag="ACG84Z_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFP9162145.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(13809..14276)
                     /locus_tag="ACG84Z_001294"
     CDS             complement(13809..14276)
                     /locus_tag="ACG84Z_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFP9162146.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(14396..15934)
                     /locus_tag="ACG84Z_001295"
     CDS             complement(14396..15934)
                     /locus_tag="ACG84Z_001295"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFP9162147.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16014..16700
                     /locus_tag="ACG84Z_001296"
     CDS             16014..16700
                     /locus_tag="ACG84Z_001296"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFP9162148.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(16901..17428)
                     /gene="msrA"
                     /locus_tag="ACG84Z_001297"
     CDS             complement(16901..17428)
                     /gene="msrA"
                     /locus_tag="ACG84Z_001297"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFP9162149.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(17512..18189)
                     /gene="pgmB"
                     /locus_tag="ACG84Z_001298"
     CDS             complement(17512..18189)
                     /gene="pgmB"
                     /locus_tag="ACG84Z_001298"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFP9162150.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(18186..19316)
                     /locus_tag="ACG84Z_001299"
     CDS             complement(18186..19316)
                     /locus_tag="ACG84Z_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFP9162151.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(19316..21499)
                     /locus_tag="ACG84Z_001300"
     CDS             complement(19316..21499)
                     /locus_tag="ACG84Z_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFP9162152.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(21496..22521)
                     /locus_tag="ACG84Z_001301"
     CDS             complement(21496..22521)
                     /locus_tag="ACG84Z_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9162153.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(22566..23393)
                     /locus_tag="ACG84Z_001302"
     CDS             complement(22566..23393)
                     /locus_tag="ACG84Z_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFP9162154.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(23390..24457)
                     /locus_tag="ACG84Z_001303"
     CDS             complement(23390..24457)
                     /locus_tag="ACG84Z_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFP9162155.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(24483..25319)
                     /locus_tag="ACG84Z_001304"
     CDS             complement(24483..25319)
                     /locus_tag="ACG84Z_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162156.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(25316..26185)
                     /locus_tag="ACG84Z_001305"
     CDS             complement(25316..26185)
                     /locus_tag="ACG84Z_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162157.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(26255..27538)
                     /locus_tag="ACG84Z_001306"
     CDS             complement(26255..27538)
                     /locus_tag="ACG84Z_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9162158.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(27552..29237)
                     /locus_tag="ACG84Z_001307"
     CDS             complement(27552..29237)
                     /locus_tag="ACG84Z_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFP9162159.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            29512..30537
                     /locus_tag="ACG84Z_001308"
     CDS             29512..30537
                     /locus_tag="ACG84Z_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9162160.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(31132..34785)
                     /gene="rpoC"
                     /locus_tag="ACG84Z_001309"
     CDS             complement(31132..34785)
                     /gene="rpoC"
                     /locus_tag="ACG84Z_001309"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFP9162161.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(34864..38481)
                     /gene="rpoB"
                     /locus_tag="ACG84Z_001310"
     CDS             complement(34864..38481)
                     /gene="rpoB"
                     /locus_tag="ACG84Z_001310"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFP9162162.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            39209..40177
                     /locus_tag="ACG84Z_001311"
     CDS             39209..40177
                     /locus_tag="ACG84Z_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9162163.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            40195..41100
                     /locus_tag="ACG84Z_001312"
     CDS             40195..41100
                     /locus_tag="ACG84Z_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162164.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            41097..41903
                     /locus_tag="ACG84Z_001313"
     CDS             41097..41903
                     /locus_tag="ACG84Z_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162165.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            42060..43028
                     /locus_tag="ACG84Z_001314"
     CDS             42060..43028
                     /locus_tag="ACG84Z_001314"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFP9162166.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(43345..43869)
                     /locus_tag="ACG84Z_001315"
     CDS             complement(43345..43869)
                     /locus_tag="ACG84Z_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFP9162167.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            44156..>45267
                     /gene="scm"
                     /locus_tag="ACG84Z_001316"
     CDS             44156..>45267
                     /gene="scm"
                     /locus_tag="ACG84Z_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFP9162168.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDST"
BASE COUNT        13513 a         9275 c         7857 g        14622 t
ORIGIN      
        1 tgaactaatt caatcatact gattctttcg tgtattcaaa attagatgct gtttaataaa
       61 attattcttt ttgaaaaaga attataacta tatcccaaaa attgtaggtt aatttaaagc
      121 ctatttcatc atcgtgattg agcttctttt tcatagacga atttctcaga tagtttagtt
      181 ttctttatga gatttttgta tatttctgac cttcgataca actcattatg agtaccttga
      241 tcaactagtt ttccttgatc catcactaca attttattta ccttttcaat agacttcaag
      301 cgatgcgata taattagtac tgtcttatct tgtattaaac gatttaaact ttcctgaata
      361 cgtttttcat tttccgcatc taaactggca gtaatttcat ctaaaattaa aattggcgca
      421 tttttcaaaa aagcccgtgc tatggatagg cgttgtcgct ctcctccaga aagtgaactt
      481 ccgttttctc cgaccaatgt atgataaccg tcaggtagtt tttcaataaa gtcttcgcag
      541 ttagctaaac gagctgcttt tttcacttcc tcatctgacg cttgactatt tccaatacgt
      601 atattttcca aaatacttgt attaaacaaa gttacctctt gaaaaacaat agcgattttg
      661 ctaaacaaag aagctggaga tacacgttta atatcatacc catcaattaa aatacagcct
      721 tcatcataat catacagtct agacactaat ttcaagatac tagttttccc ggaaccacta
      781 gcacctacta acgcagtcac ttctccttgt ttagccgtaa aagagatatg atctaaaatt
      841 ggggtattgt tatcatatga gaaagagaca tctcgcaact caatgtcaaa agatttcaga
      901 ggactatctg atccctcttg gatactggtt tccttcatag ctctaattcg ctgtatttta
      961 ggagctaaat aaaatatttc aagcactgct tctttcatag aatcgaagga atcctttatt
     1021 tttattgcgg ctagtaagta accaacgacg tagagtatag tcacttcacc cgttaacagt
     1081 aagtgaacac ctactagaat gactactgct aaactaacat atgagaaaat agaggataag
     1141 gccatgactg aaaaagtact taattctacc tttaaatgaa tcctttcact ctcttccatt
     1201 tttttgaaaa gtctgtcttg aactttttta gatagattaa agctattaat ctcttgctgc
     1261 aattctatag tttcttgaaa ttcttccgag ttttctctca aagtatcgta atatttagta
     1321 ttggctttcg tttgggattt ctttgataac aagattaaga caaaactaaa taacgttggc
     1381 aaaataacag ctaatcccat tttgacatta ccaaccaaaa gcatcactga aataaaaggg
     1441 aaaaacagag ccataccgcc ggctttaggt attgcatgac tcatcgcatg ctcaatacct
     1501 tcaacgtcag acatgatagt ttgagataaa tctgataaat tatgttttga aaaataggat
     1561 aatggtaaat ttgacaaatc gtctgcaatt tgcactctta aatgcgcact ttctttataa
     1621 gtactattat ataagttttc atactcccta tctaacaacc aatacatgaa aagcaaagta
     1681 acaaacgata cggcaaaata aagccaacgg ggctttgtat tttctaaaac taattcgtct
     1741 atcagcatca ttataatgaa tgctggtacc atattaatgc agtatacaaa aaaactagaa
     1801 atagaagctt tagttaaagc ttctgcgccc tgatcactta aagcaaattt gtttttataa
     1861 aaacttttca ttgtcaagcc tccaatcatt tgcattctca taattagtga ccaattgttt
     1921 atacacttga tgtttagcca ttaattcatt atgatttcca cgttctacta ttttcccttc
     1981 tgacaagaca agaatttcat ctacagattt aatgctggat aatcgatgag ctatcataat
     2041 aactgttttt tcttttatca gatgttgaaa agccttttgt agttcatact cattatctgg
     2101 atcaatagat gcactggctt catccataat aacaatcttt gcatctttta aaattgctct
     2161 ggcaatagct atacgttgtt tttctcctcc tgacagataa actcctttac taccaattaa
     2221 ggtatgctct ctttcgggaa atttttctaa aatcgattcg caaccggcta atcttagcgc
     2281 gtcaaatact ttacttgctg gcgcttgagg atttgctata gaaacgttat cgtaaatact
     2341 ctgattgaat agtttcgtat cttgaaagac aaaagcaatt gtgttaataa ttgtgtcttt
     2401 tgaatagtga tttaaaggct taccaccaat tttaatctgt cccttatcca cattgtagaa
     2461 acctgaaatt agtttagcta tcgtactctt tccgcttcct gattttccta ctaatgcata
     2521 aattcttttt tgttctaaaa ctaagttgaa attttctaaa acacactctt ctttgtatga
     2581 aaagctgaca ttttcaaatg caatgtcaca atttttaatc tgtgtctcgt tcccatattt
     2641 tagttggtct tgcttcattt ctaaataaag ggagtctagt gtttcgactg catatcttgc
     2701 ttcaaacaag tgcatactta catacattat tctcatgaaa gaaacaaaaa taattccact
     2761 taaaaaaaac aacatcaaca agtcaacagc taatatcttg ggagtggtaa gagaagttat
     2821 aaaaaaggtt ataggaacta tcaaaatgca aactatgcca aaaaatagcc attgaaaaag
     2881 aacaaaaggt gttttcccac tcaaagaata cttatatgca aacttagcat aatcgttaat
     2941 tgctttattc aaggctttaa atgatgttac tttagcacca aatatcttta taacttgaat
     3001 tccgcggata tattctaccg tttcagagct taacacatct aacgattctt gatatttttg
     3061 aataaaattt gtattctctg tcattttctt taacaagaat acaccaatta ctaacatggc
     3121 gattagaacc aatccaattt taaagttaat gaaaaagcct aaggcaactg ataaaacagg
     3181 tgttactatg gcttgagcac tatctggaat caagtgagca attgccatat gtgttttagc
     3241 cgcgttgtca tcaattgtct ttcgaatata tcccgaagaa tttaaatcaa aaaaacgaaa
     3301 acttgcttct gttaaaccgc taattccctt ttttctcaaa ttagtctcta agcgaaaccc
     3361 aaggatatga gaaaataagc cagaaaaaat ataaaataaa gctcctaaag ttaaccaagc
     3421 aacagtttga accgcataac tcttagctaa atattcatct cctacaataa ttagagactg
     3481 aagaaatttg taaatactgt aatatccata gactgttaat acgacagaaa aatcagaaaa
     3541 taaagtggct aaccatccgt agtatttcat tttagggaca taactaaata attttttgta
     3601 tactttcatt ttttcctccc ccgcattcaa tttcttctct tattcgttta caactgttaa
     3661 tgctttccgt aatagcgtaa attagagatg tacaaacaga taaaaggtaa actacgttct
     3721 attttttgta tttttttaag acttttcttc caatcaatac accaatcata gataaacttg
     3781 ctacaactaa cactgaaatg attccccata tacctaccgc atagtggatc attgcatcca
     3841 ttgttgcagc agattgtcct ttatctatcc aatcttgacg aaaacgatct gtaaagaacc
     3901 atataggaat ccactgtccg gcagcactgc ctaattgcat tagagcccaa gacgcaactt
     3961 gaggaattgc tcgatcatat ccaaatacag atagaataat atcagctaag atcgccatac
     4021 taatcgaact gataaaccaa ggtaagtacg ccccgcccat taacgtaaaa aataacaata
     4081 aaacaattgt gtaaatagta aaaattcctt ttctagggta gttatagcta atataaacaa
     4141 atatgattcc agataataat ccaaaaatcc cgggggatat gctgtgacca aacgccccac
     4201 caatactact aaccattatt gaaaaaaagt aaattactag ggaaataact gtagctaaac
     4261 caataaaaat ataatctttt gttttcatat atattctcct caattctatt tcgttatgtc
     4321 attaaaaatc tgttctatca aagttgaatc ttctactcta agttttatat ctttttttat
     4381 tccaccattt tttaaataaa taattctatt gcatgtttta taaagaaatt ccggatcatg
     4441 agtagctata actactgcac ccttttcttt taagtcttta ataaggtcag caatcctttc
     4501 catattaata taatccaacc cacttgtagg ttcatcaaat agaaataaat tagtttttga
     4561 caatgaagct atagaaacca ataatctttg tttttctcca ccggataaat caaacggtaa
     4621 ttgatctttc attttataaa gttccatttt ttttaaaatt ttttcttgct gatctttact
     4681 aactatttca ttccccaggg ctaactcgct cctcactgat tctgtgaaaa attggtaatc
     4741 catttcttgc attactaaaa acggcgatga caaatttttt ttattttcga ttatctttcc
     4801 tttggtaggg cgaataatct tcatgagtat tcttagtaag gttgttttcc ccacaccgtt
     4861 tttccctacc aaaccaataa catctccaac tttgacatca aaatttatgt cttttagaat
     4921 attttcataa gtaatttctt caacttttaa tacatctgca cttacctttt cgatataggg
     4981 aacttcaatc gaactattaa aaatgtcaaa tttccttaat gcgttattgt tttcagtttt
     5041 taacaactga atagttgtag tttttacagt tctattttta acaaatagaa cttgatcaat
     5101 taattctttc aaatagtaaa aacgatgttc agctataaca atagtaaatc ctttattttt
     5161 taaatcacaa agtaagtcag caagtttctt agtcgctttg aagtccaaat ttgaagacgg
     5221 ttcatccaat ataattaatt tagagtttag cgataaacta catccaatag aaattttctg
     5281 ccgttcacca cttgatagcg aaaaaatgtt tttatctaat atatttgaaa gatctaataa
     5341 ttcagctaat tcattgattc ttttatccat atgctctttt gtaaatccaa agttttccat
     5401 cgaaaatact aactcactcg ttgtatttgt tgtaaagaat tgtcctctag gatcttgact
     5461 tacgtagcca atattttttg atatactttc ttgtgttaag gattgtagcg agttattttc
     5521 aaataaaatt tccccaacca attttccgtc ataaagtctt ggaataagtc cattcattaa
     5581 ctttaatagt gtggatttcc cactcccaga agaaccagta atcaatgtaa gactgccttt
     5641 ttttattgaa aaattaaggt caacaagcgc ttgttcctta acatccttat atgaaaaaga
     5701 aacattgtta aattcaaaca attctttcac ctcaaatcaa aatacttaag aaaaaaatag
     5761 taacggaaaa caggatgata tagtctaata agctcatgtt tgttttatag taagaacttc
     5821 ttttcacagg agattctatc ccctttgtta ttgcattagc ggtcatttct tcagcaatca
     5881 tagttgcacg tataagaacg ggaactaaca gaaattccaa atattgcaga ggctgaaaaa
     5941 aagacaagcg aatgtttctc atttttaaag attctttaat cattcttatt tcagaacgat
     6001 aagtcggaaa gaatctgatc actactgtaa tacttaacat tatttttttc ggtaaatgta
     6061 ttttttctaa agaggataat aattcattgc tagtatagac actaaccaac aaccatgaga
     6121 tcattacgac cggcaacatt cgaaatacaa tatataagga tgtcgcaaaa aatatagtaa
     6181 aaaactctat cttgatagca tcaataattt tcattactaa aaacagaact gaataaatca
     6241 agatgaaata aatacatgtc tttattttac gaaacatcaa tactaaaact gtagcaataa
     6301 tgaaacaccc cacttgaaat atatttccct ttcctaaaaa aataatgacc ggaaaaaaaa
     6361 tatttaaagt aatcaaggtt aacggattga tttttgacac tctttcacct ccaaaaaata
     6421 agatcgcact gttatcttaa gctgataaaa atgcaccgtt attcagataa cagtgcgatc
     6481 ttatcaaaaa gcataactga gaacaattct caatgcaagc tttttttaat taactcagta
     6541 attcaatcca cccaggaaca gaaaattgat acaatcttct ggttaatagc atagtctttt
     6601 cttttgaata gctatgcttc aatatatcat agaatgtagc gtagaatgag taaatgtaga
     6661 agtggatttc ttcttcatta aagactaaat tttgattgat cattccgata gtctttaact
     6721 tatctagaca acagactgtc tttttcgtca caaatgatgt aattttttca acaatatctt
     6781 gatatttggt tccagctgat tggaataaaa tcaaatcgaa tatacgttta ttctcaaaaa
     6841 tataattaat aaatggatct aattcattga agttctctct ccaacttttc tctatatcta
     6901 tattttctaa gtttaagagg tatttggtaa actcttcatt atacatatta ataagcgcat
     6961 taatatgcgg ctgaataatt tcttcaaata acgcttcctt agaagtaaaa tgtttataaa
     7021 aagcacccgt agttacgcct gcggtcaggc acagttgcct tatcttagtt tgctgaaatc
     7081 cttctttttc aaaatggctt agtccacttt ctattaactt ttggtgagtt ataatataat
     7141 ctctggtttc tatgggtact tcctcctaat aagatgaatt aactttatta tcttacacag
     7201 gacttgaagt ttcaatcgtt aacgtttatt actgaactca ttccttagag ctaaactaat
     7261 gagaaagagc agaataactg atacaaaaag caatcctaca agaattaata gactcatcta
     7321 aatcattcac cttttctaaa ataatccgag aaagatttaa aaaaattata tccagctatt
     7381 aggataagtc ctatcataat cactccaata gccattttct tatcctccct aaaaataaag
     7441 tcttttactt aaaacctttt ttgtaatcgt caataaattt tttcccttta tcagttaatt
     7501 gaaatcctat atctaaatag tcctcatatc taagtttagc cagcatctca cttacagatg
     7561 ctggactaac acttagaact tttgctaaat cattattttt taatttcttt tttctttttg
     7621 ataattcctg aattgctagt aaataaatta gtatagtagt cgttttaatt tgtaccatac
     7681 ctaccctcca aattatttcg aaaggccttc agcaatttta tccaggttcc atttcatcat
     7741 cgcatagtaa ctatcaccat cttgtccttt ttctgcaatt gaatcagtaa aaatcgttga
     7801 atagatagga atattggtat cttttgatac tgttttcatt ggtctatcat ccacactgct
     7861 ttctacgaat aaggagggaa cttttgttgt gcgtaatttt tcaactaagt gttttatttg
     7921 atctggtgtt ccttcttctt cagtgttgat ttcccaaatg taagcagaag gcacattata
     7981 cgctttcgag aaatatttaa agcatccttc acttgtaaca atcatttttt tatcattcgg
     8041 aattgaagca aatttagatt tagcttcttt gtctagagaa tccaattttt caatatactt
     8101 atctagattt tctttataga attttttatt atcaggatct ttttccgcta actgtttttc
     8161 aatattttta gcgtaaataa taccgttttc taaatttaac caagcatgag gatcttcctt
     8221 ccctttctca ctctgaccct ctaagtaaat aacatctatg ccatcacttg ctgcaaaata
     8281 gtctttgttt tcctctttgt tcgcattttt aactaatttt gtaaaccaag catttcctcc
     8341 agtttccaag ttaacaccgt tataaaaaat caaatctgct tttgaagttt tttgaacatc
     8401 ttcaggcaaa ggttcatatt cgtggggatc tttcccaata ggtacgatac tgtgtaaatc
     8461 aattttatct tttgctatat tttcggtaat atctgctaaa atcgaattag taactactac
     8521 ttttaatttt tcgttcgaag ccactttatc tttgtcttta ctatttattg aacatgcccc
     8581 gaatataaaa agagcaatca aaatccccag acttcccagt actgctttcc attttctcat
     8641 cataacgatc tctccttctt tcttaaaaat ttttgttttg gtgagattag aaaactaatt
     8701 acaaataaga atgccgctgt taaaacaata cttgatcctg ctgctatgtt aaaactataa
     8761 ccaataaaca atccaagcaa tgatgaactt gctccgactg ttgcagaaat aaatatcata
     8821 gttttcaagc tatttgcata taaatatgct gtagctgctg gtgtaattaa cattgcaaca
     8881 attaatatag ttcccacact ttgcatagct gttactgcta ctaaagttaa tagaaccatc
     8941 aatagataat gataaaaact gacattcatc cctattgctt ttgccattaa tggatcaaaa
     9001 gaagtgatta ataattcttt aaaaaataga actactataa ccaacactaa aaccgaaacg
     9061 ccaattgtaa tccacttatc aatatcttgt acagctaaaa tatttccaaa taaaatatga
     9121 aataaatccg ttgagctatt tgcaactcct ataaggataa ctcctagtgc taaaaaagaa
     9181 ctgaaagtaa taccaattgc tgtatctcct tttattacac tattgctttt tataaaagta
     9241 ataatgatag aagctaatag accaaataca atcgcaccaa taaaaaaatt aatacctaaa
     9301 atataagaaa ttgctactcc tggcaaaaca gcatgagaaa tagcatcacc cataagagac
     9361 attcctctta aaataataaa acaacctact gttccagaaa caatccctat aactacagat
     9421 gtaattagag cattctgtaa aaagtgaaag tcatacagac cattaataaa attttgaagc
     9481 atattattcc ccctctccaa taaatatagt atctccatag gcttttttta aattttcttc
     9541 attaaataca gattctacac ttccgtgagc aattagattt cgattcaaaa gaataatatt
     9601 atcaaaatac ttctttacct tgcttaaatc atgatgcaca attagcactg tttttccctg
     9661 atgtttcaat ttttttaacg tatccataat tattcgttca ctaactaagt ctatccctac
     9721 aaatggttca tctaaaaata tgaaatccgc attttgagca agacatcttg ctaaaagtac
     9781 acgttgaaat tgtcctccag ataattctcc tatttgatga ttagaatatt ttcccatatc
     9841 gaccttttcc aaagcctttg aaactctttg ccattctgca tttttaattc tttgaaaaac
     9901 tttcattccg gcatatgttc ccatagatac acattctttt acttttattg gaaaagtaaa
     9961 atcaatatca gctttttgct ctacatatgc aatcttcacc agttttttat tgatatcttc
    10021 attattaatg gagacctctc cctgatgagg gataatattt aacattgctt taagcaatgt
    10081 ggattttcca gcaccatttg gaccaataat acctgttaaa gcaccttctt gtatttttaa
    10141 agaaatctcg ttcaatgcta aaaaatcgtt ataacaaaca ttaagctttt tcacttctaa
    10201 cataactttc tccttctaaa tgataatgat tatcacgatc atatggtata caaaaattat
    10261 attttagtca accctaaatt ttatagttta gatttttttc tgttgctgaa gattagaatg
    10321 acaaaactat ttgaaactac gcgtatagta agtagctttc aaaatatata aaaaaggagc
    10381 gttctcaaat gagaacatgc tcctaaaact actttattgg cgtatggaaa aattatactt
    10441 gaagtggata gcgggttgaa taagttgata agcatcaaaa catttataaa aattattcaa
    10501 gactatgtct gttccatata caaatatgaa aatcagtaaa ctccatttaa cttttttcgt
    10561 agtgtgtctt tttatacatg tttatcgtta ttaatagtga ataggaaaaa aactattttt
    10621 gatcattgac aattaaatac aatttttgaa taacgatccc tgctattcga gctagaaact
    10681 caagtacgcc atgacctgat tagcgacaaa tacttagaga tttctttttg ttctgggaaa
    10741 acaaaatgcc atgacaatag cagcaaataa tgatacttcc gtaaggctcg ccgtaaactg
    10801 gggagaggtg aaattcctat gtgcttaccc aaagcaattc aaaaatttca taactactat
    10861 tttaggagat gattttatag aatccagagt ctacctgaat aaaaaacaaa cctgtgcatt
    10921 tctaggaatc gataataata ctctagataa gtggattcgt atatataatt tcccagtaat
    10981 aagagttggt ggtgtagttc gctttgacgt agaagatatt aaagacttta tgaatacatt
    11041 taaaataact tgaaattttc ttctcgccgc atatactaaa attagtgaaa tatactgcct
    11101 tacttttttt aaggagtgag gattttgcct acaaagcttt caaatgggaa atataaaact
    11161 aatctgagat atccaaaaag gtttaaagaa ataacaggaa ttgcatcaga aaagtatcaa
    11221 aaaacatttc caaataggca attggcgatt aaagccgaaa atgatatgaa gaagaaaata
    11281 gaaaaagttt tgagagagga gaatgcaaac tcattagaat taaaaggaaa aataacgttt
    11341 aaaaaatttt acgaatctaa atggcttcct agatatgaat taggtcaaac aattagatca
    11401 aacaggcctc ctagtgatat aaccattagt aatacaaaag atatatttcg gttgcatatt
    11461 ttacctatgt ttggtgaata cgcaatgaat tatctaaata tcaatactga gataatatca
    11521 gatgaattaa ccaaaaaatc gaaagaatat gcaaatataa aaatcataaa aggatatgtt
    11581 cgttccatgt tcgatattgc agaaatacta aattatatcg aatttaatcg aactactaaa
    11641 attattcaaa gtatcactgc acctaaaaaa aatgctttag aagaaaaaag aatacaagaa
    11701 ggtaagcaag cactatcatc aaaagaactt actaattgga tagaagcagt aaatgatgat
    11761 tttaataatc atttacttac ttttcatgat tacacacttt ttatgattac cctgtatctt
    11821 ggtgatagaa aaagtgagac ttacgctttg caatggaaat atattgattt tgaaaaacaa
    11881 acggtccgtc ttaaacatac tttagataaa tatcaaagaa aaaagtttac aaaaggtcga
    11941 aaagataccg tcattcaagt accagaagtt gtaatgacat tgctaagtga atggaaatcg
    12001 gtacaagctg atcaattgtt gaaattaaaa attaagcaaa cgttagatca gtatctcttt
    12061 acttatacta aaccatctgg agaagtaaat tgtcctgttc atgccgatta cctaaactat
    12121 cgaatcaatt caattaaaag aaggcatcct gacttagttc atttatctcc acacaaactc
    12181 cgtcatactt atgcaactat agctagacaa ggtggagcag atatgaatca aatttcaaat
    12241 gctttaacac actcagatat ttctacaaca aagatatatg tgaacacacc agatatagtt
    12301 gataaggctg tttttgaagc ttttcagaga ggattgaata agtgtgattg atatgtgttc
    12361 ttaaatgtgt tcttaaaaac aaaagaagca ctttccaaat aattgaaaag tgccagaaac
    12421 gttgatatat aaaggatatt aacgttttga gaattgtgaa gctttacgtg ctttcttaag
    12481 acctggtttt ttacgttcga ccatacgtgc gtcacgagta agtaagccag cacgtttaag
    12541 agctaaacgg aagtcaggat caacttctag caatgcacga gcgataccat gacggatagc
    12601 tcctgattgt ccagcgtatc ctccgccgtt tacgttaaca aatacgtcat atgcgccttt
    12661 tgtttcagta acagcgaaag gttgattgat tacttcacgc aagtcagcat gtggaatgta
    12721 ttcttcaaca tcttttttat ttacagtaat tttgccagtt cctggtacta gacgtacgcg
    12781 agcaactgcg tttttacgac ggcctgtgcc gatatattga acttgtgcca atgaaattcc
    12841 ctcctattag attaagtttg tgatgtctaa aacttctggt tgttgtgctg catgtggatg
    12901 ttctgctcca ccgtatacgt tcaattttgt aaattgtttg cggcctaaag tgtttttagg
    12961 aagcatacct tttacagaag tttcgatcaa acgacgagaa tttttagcac gcaattcgcc
    13021 agcagtgatt gatttcaatc ctcctgggta gttgctgtga cggtaataaa ttttgtcagt
    13081 cgctttttta cctgttaatt tcactttgtc tgcattgatg acgatgacga aatcgccagt
    13141 atccaaatga ggtgtgaaag ttggtttatt tttaccacgt agtacagatg caacaactgt
    13201 tgaaagacgt cccaatggaa catcagttgc gtctactaca taccatttac gttctacttc
    13261 gcctggtttg gccatatatg ttgtacgcac gttattttcc tccaatttaa gttctgatgt
    13321 ttgacataca cttcgagttt ccggggctct ttgtggggca aacaatacca tttaacatat
    13381 tacccgctaa tctagtcaat gtcaacgttt ttctgcttga ttgaaaaatt tatatgaaac
    13441 tttacttctt ttctttcttt tatataaaag ggtcgtttcc tgtcaaaatg aaaaacaaaa
    13501 agaggctgtg acaaaagtct tgtcacaacc ccttattttg aataaacggt gttctcctgc
    13561 caactcctcg gtcacaagtc acaatatcca taaaacataa gaagctgttt tttaaaattg
    13621 tttcttgtga ctcggagctg aacggcaggc ttacaacctc ttggtaaacg gtgttcaatc
    13681 agctgaccct cggtattagc tcaaaaaacg gcaaaatatg aggaactatt ttgacgtttg
    13741 tttctctaat actcaggtca aaacgctgat ttcacaacct ctttttcggt caagttcaac
    13801 aacagttttt acgcgtcgat ctctggcgct ttgcccaaat gagcttggat catccagata
    13861 cgtttttctg tggctgtttt gaattcgata aagatatctt gtgttggatc gtcgccttct
    13921 tctccagaaa cttcgattcc tttttggtaa agatctgcta gataacgata gcctgcaaca
    13981 agtgtttcca aacgttctgg aatagtacga tcccagcggc caatttcatc agggattttt
    14041 gtgttatctg caaattcacg caatgtagaa taaggtgaac cgtctaatgt gatcaagcgt
    14101 tcggatactt catctaactg agcgttcaaa tcatccatga actcatccat cattgggtgc
    14161 aatgtaagga aacctggtcc tctcatgtac caatgtgttt ggtgaacaac aacagacatt
    14221 tggcttagat ctgcaactaa ttgatttaat acttctttgg tttgttggaa tttcatcttt
    14281 cttgcctcct aacattttct tacacttaaa ataatagtag actttcaatg aaaagtacaa
    14341 caaaatcatt tacctgagaa cgattttcag ttcgcttttt tatccgtaaa gccaatcatt
    14401 tttcagaatc agctaattct tctcgcagtt gagcaaattg ctgataagtc tgtgctaaat
    14461 gcttttgtgt cgaaacaaat aatggataga ttttctgata ttttttatga tcagtttctt
    14521 gtactccaac ttgctctttc aattctatca attcctgtgc ttcactgata ctttggatct
    14581 ttccgatgct tctccagcct aaaatcacag ctcctaatgc ggatgcttct gtgacagtag
    14641 ggaaaacaag cgggtaaccc agtacatcag ccatcatctg acgaaaaatc ggagattgag
    14701 caaacccgcc tgtagcacgg atctctgtga gctgattttc ctggcaaact ccttttaaaa
    14761 tccgataaag gttgagacag atcccttcta gaatcgcctt catcatttct ttttctgtat
    14821 gttgccgctg taaaccgata aaactgccaa acgcatctgc gtcccaaagc ggtgctcgct
    14881 caccaagtaa atagggatga aaaatcagac cattggcacc cgctggcaca aaagcgatag
    14941 ccgaaagcag tgcatcatat ggattttctc ctttttcttt agcagattga acgacttcct
    15001 gtaaaaatgt atgccctgcc caatcaaaga tgccagcacc attgctagtc gctcctccca
    15061 ctacccaatg tttctgatcc agaacataac aaaacgtctc catttctgga tggaactgag
    15121 gctgagtagt aataaaacga agtgctccgc tcgttcctac ggtcaaagcg gcgatcgtat
    15181 caccaaaagc acctaaccct agattagaaa gcggcccgtc tgcccctccc aaaacaaatg
    15241 atatatcatt tggcaaacct agttctgctg ctgtttttga tggtagacct gttacttgat
    15301 aggtggaagg aaagacttgc ggcaattgct ctattcgaat gttcaagtag tcaagcactt
    15361 cttctgccca ttggaattca tggatatcaa aatatccagt tcctgaagct gttccgtagt
    15421 cgctgatcag ttcgccaaac aatctataaa agatatagtc tttgataccg acaaaataag
    15481 cagttttttt gaataattca ggttggctgt tttgcagcca cttgattttg ttcaatggtg
    15541 tcattggatg aatcggcgtc ccagtctgcc gataaaattc tttgccaagc acggtatatt
    15601 tcagtttttc tgcttcgtcc gctgctcggt tatctgccca agtgatcatt cgagataacg
    15661 gtgttttctc ttcatccaac aatatcaggc catgcatcgc agaggagaag gagacaaatt
    15721 gaatgattgt gtctgaaggc aactgtttaa ttacttcttt tataacggtg cagacacctt
    15781 gaaagatcaa ttcctgatct tgttctgcca tcccttgtgt ttcttggatc aaagggtagc
    15841 gaaaataagc ggatgctgct tcttgggctt catctgtgaa agcaactgct ttggtttgtg
    15901 tggttccgat atctaatccg attgaaacgt tcattttttc acctcaaatt ttatgtatgt
    15961 acaaaaattt agtttaagct tgcgtatctt ggttttgaaa agggggagat ggcgtgttac
    16021 tttattttat cattggttgc tgtatcggat catttttatg tttaaccgcc cagcggattc
    16081 cgttaggtca ctctattatt tatcctagat ctcattgtgt caaatgctgt cgttcgcttt
    16141 cttggtatga attgattccg attctctcga tcatcgtcca acgatttcgc tgccgctatt
    16201 gcaggtgtcg gttgcccttc tactatttgt tggcagaagc cttatgtggt ggtctttttg
    16261 cctggttctt tactttttct tccgcaagaa atttttcgac gttcatatgg atgctttcgg
    16321 ctttgctatt ttcgttgatg gatttatttt acttcatggt ccattctcac acgctattct
    16381 gttcttgggc aattttatgg attttttggt tgcaggccgg cgtcttccaa tggcaaagtg
    16441 tgctgttaac gtttatcgta ggcggtgtgt gccttcgcta tggtcaatcc tatctcggag
    16501 ctggcgatac tctgttgatg ctttcttgga gtggtggctt gtctctagaa gagttgcttc
    16561 agatcttgtt tcttgctagt ctgtttggaa tatccgtttt ttctgtttac tttatctgtc
    16621 ataaaaaaaa gttggaaaag ctgcctttca ttcctttttt gagcagtgcg ttgctgattg
    16681 tccttcatct taggtattga aaaaaggttg tgacaaacga cttgtcacaa cctctgatat
    16741 atagtgttct cttaccaaat ccttgtgact tggagctagg cgacaggttc acaacctctc
    16801 cactaaatgg tgttcaatca gctgaccctc agtattagct caaaatgctg gttttacaac
    16861 ctctgatata cggtgttcca taagtagctt tttcggcttc ttatttcttg acgccccaat
    16921 gtcgacgaag gaaacctgca cgtccagaac cttctcgata aagattgtaa tggagcttgt
    16981 ttttcttgta ataatcctga tggtaatctt ctgcaggata aaattcgctt cttggttcga
    17041 tttttgtcac gattggctta tcgaatcgcc cgctgtcttg caatgcttgt tttgaacgct
    17101 ctgcaatatt tcgttcttct tcatcattat agtagatcac tggacgataa gaatcaccgc
    17161 gatcagcgaa ctgtcctaat gcgtcagtcg gatcggtttg ctgccaatag atttccacca
    17221 actgatcata agaaataact tctggatcat attcgatctc tactgcttct gtatgccctg
    17281 ttgtgcctgt tgttacttgt tcataagttg gatttggtac atgcccgcca gtataaccgg
    17341 atgtcacaga aatgatccct ggctgctctt caaatggttt gaccatacac caaaagcatc
    17401 cgcctgcgaa aactgctttt tttgtcatat aaaatccccc ttttttctca tcataccttg
    17461 atttccaaaa ggaggataac gttttgcttg tgacagaaaa aacggaaact attatatacg
    17521 tgatacggct tctgataaat gccaaaacga acgtacttga tcaaaaacgg ttaaatcagg
    17581 aatcacatat tcagcagaag gaagatttat gttttcacct attcccaata catgcatgtt
    17641 accagccaaa gctgcttgac aaccagcttc tgaatcttca atgaccaagc atgcatttgg
    17701 cggtacattc aattgctgtg ctcctttgag aaaaacttct ggatcaggtt ttgcttttga
    17761 tacttgcgtg ccgtcaataa ggacatcaaa ataacttgtc aaattcgttt tttctaaaat
    17821 gaggcgtgca tttttgcttg ctgatcccaa tccgatcttg atgtttgttt ttttcaagta
    17881 ctcaagaaca gctattgcac caggcaaaac ggatgtttca tccatttttt gaatcgcttg
    17941 aagatataga ttgttttttt gctcagcaaa ggctgatttc tctttttctg agaatttctg
    18001 ttccattttt ccaaatgaca gcaatcgctc tagtgactcg gttctggata ttcctttcag
    18061 ttgctcgttt tctttctcag tgaatggaat ggacagctgg ttagctaaaa ccagccacgc
    18121 ttcgtaatga taacgagctg tgtctacaag aacgccatct aaatcgaata gtgctgcttt
    18181 gattttcatc gattacctcc ttgaaaatga acgacttgaa gtaaagatgc gatgttttta
    18241 gctgtgcgat gaagattatc agtggcttgc tgtaaagctt cttgtaaagg cacagctgca
    18301 ggaaggatcg gaaaaacggc cgaaatgcca acatctgctg ctttttcgct tcctttacca
    18361 acacttccgc aaatagctat cacaggaacg ccctctggta ctcttctagc aatcccaact
    18421 ggcgcttttc cttttagact ttgtccatct agacgtcctt cgcctacgat tacgaggtct
    18481 gcttgctgta cccgtttatc gaactccagt aaatccaata cgtagtcgat gccagagact
    18541 attttccctg aagcaaatgc taacagtcct gcacccattc caccaccagc actactgccc
    18601 gatgcctcga ttacttgagg ggcaaatctc atataaaaat catgcatggc ttggtcagcc
    18661 actgctaatt cattttcttt caagcctttt tgtggtccga aaacaaaaga agcgccttct
    18721 tttccgcata aaagattagt aacatcagta atgacagtga ttttggcttt aatcagctca
    18781 ataggcacgt tcgttttatc aactgtagca attttaccta gattttctcc cagtgcttct
    18841 actttttgat tatcttgatc gtaaaaagca taacctagac cttctgccat gccgatgccg
    18901 ccatcgttgg tactacttcc gccaacgccg atgatgatgt gtcgaacacc ttgttgcaac
    18961 aattgtcgta tcagttctcc tactcctcgc gtggataacc taagtggctg ttgttggttt
    19021 agtgggacat ctttcaatcc gacgatttct gccatttcaa aaatcgcagt ttgaccgtct
    19081 gaagcgtact ggatttcttt gtttttgcca aatgcattag taacgactgc tgtttgccgc
    19141 ttcaacctta aactgtctgc taatgatgaa accgttcctt ctcctccatc gcctataggt
    19201 agcagatcat attcagcctg aacaaaaact tcttgaaaac ctgattgaat ggcttgtgct
    19261 gcctctaagg ctgtcagact ttctttgaaa gaatctggcg caatcagaat acgcattatt
    19321 ttcccctccg ttccaagatc agttcttttt ccagctggta ttggtctcca ttgacaaaaa
    19381 taggtaatgt ttctttcgtc tcttttttta ttactatttg tttttttgtc aaaacaaata
    19441 gcaacctgtg atttttccaa ataaaaggaa aagaaatttt ttcccatgct gaaggaagtc
    19501 ttggagaaat agaaagagtt ccattcgtta ctgtaatacc tgaaaaacca aatataactg
    19561 ctagccatag tgctcctaat gaagcagcat gaattccgtc atctgatgaa tgcggatctg
    19621 gtcctaaatc aatcaggcac gcttcttgga ataaatgata cgcccattcc atttcttgga
    19681 tacggcaagc ctctatggcg tgaatcgctt tactcaacga tgagtcgtgg attgttttgt
    19741 tttcatagta atgcaaattc ttagaaacga ttggttgaga aaaatactca ggtaataagt
    19801 ataacagcat gacaagatct gcttgcttgc tgacttggag ttcatttact tcgctacggg
    19861 cataatcaag taaaatagac tggctgccag gacgttcttt gtaagtggtc aaatcaataa
    19921 ctggcttact gagatacgtg tcatcttgcg gaatcagctg ttctttgtta ggcactggca
    19981 aatataactt atctaaaaaa ttttgacatt ctttcaaaaa aagcggatcg ccagcttgat
    20041 atttaacagc taaggccaca ttataatgcg ccagatagtt cgtatatgca ttattgtcga
    20101 tatattctgt gtattcatct ggaccaatga ctctgtgtat ctctaaatga tcatcgactt
    20161 ttacagctct gctcagccaa aaagctgctg tttcatgaat gagcgttttt ccctttgttt
    20221 ctaaaaacga ttgatcctct gttgcttgga catactcttg aacggcataa gcaaggtctg
    20281 cactgatatg atgttctgcg gcagctgaag caacttcttg tcttgttccg gttttgatat
    20341 tcaatgcagc aaatttgggt gtctcttcct gaccagtgtg tgcgctttcc catgggaaaa
    20401 gtgcaccttg atagtgataa tctcttgctt tttgccgtgc gccttctaat cgatcataac
    20461 ggtacagcag caaattcttt gctacttcag gaaactgata taaaaagaaa ggcaggataa
    20521 aaatttccgt atcccagaaa acatgccctt tataaccttc gccagttagt cccttcgccc
    20581 ctacactaac acttggatca ttgcggggag tcataatctg taaatggtaa gcagcgaagt
    20641 ccatcgctaa ctgatcgaaa gaagaatcgc cttggatcgt tatccgatgc tgatgccaaa
    20701 aatctgtcca ataagacatc gactgctcta aaatttctgt ataactaacg cttttctggg
    20761 cttgggcaat acttttctta aacgggtctg tttgctgaag agaggtagag agcacgatga
    20821 tcttctccag cgtaaaggac gtattttttc tgatcttttc tgaaaaggaa gcggtgatcc
    20881 ggcgattttt tgcttggaat acacctgctt tattgaattt agctgcaatc ccaatatcaa
    20941 ttttactttc tgttgtctgg taggatgcac tgatcaaatc gtcaccaaat actcgcagtt
    21001 ctttttcaac caactgctgt gtaccaaaat tggtttgctg tccatcgata cccgttttca
    21061 catctacttg gcagtcttcg gtcaacggct tgatgaccac tttcagggct gcctgatgga
    21121 gattattttg atcagcaaca cgacaagtaa tgacttccac tttttttcct tgagcagttt
    21181 caatgagcgc atagcgttta agctctccca tttctaaatc tagtgcccgc tcgtatgcaa
    21241 gaactttcat cgtctcaaga gaaaaatgtt caccgtcgat ttttatttcc catctgatga
    21301 catctgggag attcactaac tcggctgatt ctgctcctaa aggtcggtta tatacaccag
    21361 ctgcaaacat tccccttact tgattccgat agtcttcctc ctggcttcct ctgataccaa
    21421 aaaatccatt tccaatggtc atctgactcg catacttatt gatatactct aaatcaaact
    21481 gtttttcttc tactttcata aggtaataac ttctcctgtt tctgccgaac gatataaatt
    21541 ttccaccaga ttctggatga catatccttg ccagccatct gcaatcatct gagtctggtc
    21601 accgagcgcc cgattcacaa aatgagccat acttagttca tgtgggtcat taactggcgt
    21661 ggtcttttgt aaggaaacca gctttccatc tacatcttcg aatagttcgc ctggatacag
    21721 attagcacct gcctgatcgc cacaaaaagc cacattcagt ttgtcttctc tgatattcaa
    21781 agcaaacgaa gtattcagtt ggatgatctt gccgttttct aattccagtg tgccaaaaat
    21841 tgcatcttct actgtgaatt tgcttggatc ccatttcccg aatttccctg aatttttttt
    21901 cgtaccaatt ttttggaagc tgtacgcccg aacgcttttt actttaggaa atccagtaat
    21961 atacatcgct gtatcaagca tgtgaatgcc ataatcgatc aaaggcccgc ctccttgaag
    22021 ttctttgtcg ataaacgttc cccagcctgg aacaccagac cgacgaagcg cattcgcttc
    22081 tacgtaataa atatccccga gaacatcaag atgattcttg atcattgttg cttcgtcaga
    22141 aaaacgatgc tggaatccat aagccaaaat ctgcccgttt ttatcggctg tctctgccat
    22201 ctttcttgct tgatcagctg tcatagctgg tggtttctcg cacatcactg aagcattagc
    22261 ttcgagggca gccaatacat gttcgaagtg aaagcgattg ggtgtacaga cactcacgat
    22321 atcgggagaa atctcattca gcatttgtgt aactgatgta tacgcatgag aaaatcctgt
    22381 acgtcggcaa aagtcttctg ctcgctggct gactggatca accacagcgg ccaattctaa
    22441 gacatctgat cttttttgat aataagcagc atgtactttt tctgctactt gtccagcgcc
    22501 tatgattgct actttcttca tttatttctc cctcctttgc ttatttactt attgttattc
    22561 tttctctatt ctttctctaa atcatttaaa tgacgcgctg tttccagaca gtttttcaag
    22621 tattgcaatg attcctgata aattttcact tcattttctc ctcgcaaacg acattcatat
    22681 accatataac cttcatactc attttgaagt agcgtttgaa aatggcgagt aaaatcaatt
    22741 gcgccagatc ctggttggta gcgatgatta tctgctaaat ggatatgacc cacatactct
    22801 ttttgcgtag tcaatgcttt tgaaatatca tcttcttcaa tattcatatg ataaaaatca
    22861 gcgatgatct gcacatgttt caattgatta gagtcaatgt aatgacgcgc atccgctaac
    22921 aaattgatca tatggtcttg gtatcggttc aaaggctcca aataaataac cgtacctgtt
    22981 tcttcggcta ctttatctaa ataacgaagt gattcgctga ctgctttata gtctccttct
    23041 ttgcttcggg gtgaaaccat cggcggtaat cgataagtga acattcccca agctgctggg
    23101 ataacgattc ctttgcctcc aacctcgctt agtgcacgca aaatctcagc aatttgacgt
    23161 acaccattaa gacgccgttc ttcgataaag tcaccgatcc acccatcgta gccgttacaa
    23221 gctgtcacta ctgggatccc tgtttctttg attgcctgtt tgactgtgtc gatattttct
    23281 attaacaact taccgtcgat ttcgtattct tcaaatccac agtctttgat aaatctaaat
    23341 ttttctaaaa tgtctcttgg gaaaaatgct tgatcttgcg taccgaattt cattgttctc
    23401 ctcctcggac ttgaacgccc attttgatac tttcttctgg gtgctggtct acataacgca
    23461 tgtaagcttc tgcgctttct gcaaatggca caactggatc aatgatttct tcacaatcca
    23521 agtaaccgtt catcaataat tcccaacatg tgtcctcgat tcgtttacgg ttccatcttg
    23581 ggtaatctgg gtttggttca ctagatgctc gagcaaagac gatttttgca ttattgaaat
    23641 gtgcttcgcg accaagatta aacccagctg gaaaaggttt agcaaaggca acataagaaa
    23701 tgatcccgcc atagccgatc cctcttaaag aagcttgtaa tgcggcagca ctgccactcg
    23761 tttcaataac tgaatctact ccacgtttat ctgtcaattc ctttagacga aaaccgacat
    23821 ctgctttcat aggatctagc gtgtaatcgg caccgtattt ttctgctaat tctctacgct
    23881 gcgctatggg atcgatccca acgatggtag tagcacctgc ttttttagct aattgaatcg
    23941 caatttgccc gatagcgcct aaaccgaaga ttgctacagc atcacctgct cgaacatgtg
    24001 cttcccggat accacctaaa gcgaattgag caggatcgta acatactgca tttttccatt
    24061 gatccaaccg atcaagttta cgtagtttat aattatcaac accgtttgta atcagcgttt
    24121 cacgaatggg tccataagtg cagactaact ctcctttttg atactctgtc accaaactgc
    24181 ccgtttcttc gatcgtaccg acaatcatat ttcctaattg aaattcgcca aataccacac
    24241 cgcgttggct tccttcttct cttggcaaga ataggcgcca ttcttctgaa aattcttcat
    24301 cgataaatgg acttaatcct ctaaagtcga caatttctgt tcctggtttt ggagtagcga
    24361 aaattactcg gatacgtact tcgttctttt cgatctcacg gtcttcgtaa tctttgaatc
    24421 cggctattct tggttctaat gcaactaatt ttttcatctt ttctttcctc tttcttttct
    24481 ttttatcctt ttacgccgcc ttcgactaaa tcacctttaa taaatcgttc agataacgca
    24541 tacataatga tgactggtaa agcggtcacc aatgaagcgg ccatcattcg tccccaaatg
    24601 tagtctggtg tactgaataa tgtgttcaaa ccgattggta aagtaaattt ttcggaggtc
    24661 gacaggaaaa tcgaagcaaa taaataatca ttccacgaaa ccataaagca ataaacgaag
    24721 acagaaatga ttccagaaat agccaatggt ataatgatcc gaataatgat ctggatccgg
    24781 ctaagaccat cgatcattgc tgcttcttca atatcagtcg gaatcgtgtc aaaataactt
    24841 tttagcatga atatcgcagt aggaagtgtt tgaacgacca tcgtgataat cagtgctgta
    24901 ttggtatcat acaaacctag accggaaatg attttaaata atggaacaac gatcaaaata
    24961 ccggaaaaca tataaacggt gtaaaagcta gcattgattt tcgagcgagc tttgaagcgt
    25021 agttttgaca aagcgtatgc cccgctgatc ccaatcacta ctgcagttac ggaggctatc
    25081 aaggagatca ctaaactatt tttgaaatac atgatgaatg gaaaaatctc agcattgaaa
    25141 atatcctgat aatgttcaaa agtccattct ttcggaaaaa tagtttgtgt cgttgcaatt
    25201 gcttcttgtg aatccttgaa tgatgtcatc agcatgatca aaaatggaaa caaattgaca
    25261 gctaatagca acaaaatcgt cgcgtaaaat aagattttcc tgctcttttt atttttcatt
    25321 tcaagtccac cttctttcgt gagagcaaga cgaccgctgc aataatgatg aacaatagaa
    25381 tcgatatagc tgctgctttt ccaagatcat tgaacgcaaa ggctgtctga tacaaataaa
    25441 cgcctaagat attgacttta ttcgtcagta gatagacatc tgtaaacata tagaacatcc
    25501 agatagatcg taaaacaatc acagttgcta gtactggttt gattgccggc agtgtcacga
    25561 tcttgaactt ctgccaagca tttgcaccgt ccatttcagc tgcttcataa agcgttttgt
    25621 cgactgtttg caaaatagcc aaaaatgaaa taaacgcata cggatagtat ctccagatag
    25681 caaacaaaac gaccataaag aagctagcaa ctggctggtc gaaccacagc ggtgcttcgt
    25741 tgaaaagctg caacctatct actaacagat cattgacgat tccataacta ttattgaaca
    25801 tatatttcca agcaaaaatc aaagaaatag atggcgtaac ataacttaat aaaatcagtg
    25861 aacgcaccgt tttcctaaat ctgaacttgc ggttaagcaa aatagctacg gctaatccta
    25921 aagctgtact gcctgctaca actaagaatg tgtaagcaac tgttaaacct aaagaacgat
    25981 aaaattcact atcacttaaa atttcaagat aattgcttaa tccgataaaa acggcgtctg
    26041 agttaggatt cagcggcata tcgaaaaaac tgatctgaat attggaaagc attggaatca
    26101 gcactaaaac agctaataaa agcatgcttg gtgctaaaag tcccatggct aattttaagt
    26161 cagaatgttt ccttggacga ttcattgaaa cctccccctg ataatctgcc aatagctatc
    26221 tacttttttc gaacaccatt ggcagaactt cttgttattt cgtatttttt tgtgcgtcag
    26281 ctaaagcttg atcgacatct tcgtttccga cagttacttg gttcactgct tttccgatca
    26341 cacctgagct tgtgatatct cccattttcg tgaaattctt ttccccgact agtccaaaga
    26401 cttgtacttc atcaaaagca ctagcaatct cagatggcag ctcgccaaaa gacttgatga
    26461 cttcattttc tttgtaacca tccagttcga ctacttgttt attcactggt tgagcaccac
    26521 caggagacat caagacccac ttttccatgt ttttcggttg agataagaaa gctgtgaatg
    26581 cttcagcagc ctctttttgt ttctcgtcta gaccagaaga aatcgtcaat ccagatactg
    26641 tgccatagac agcttgatct ttttgtgttg ggatagcaaa accgatattt tctgagttcc
    26701 ccgcttcata aacagaaggc aaaatgtaag ttgaatagat tgccattggt gctgttccat
    26761 tcatgaaagc atctttgatt tctgtcacat cattagagcc tggcatcgtg tattgggata
    26821 agttttgata aaacgacaat gcttctctca tcttttccgt atcgatcgtt acctcgcctt
    26881 catcatccaa aacatttgct ccatttgaca aagcaaattg agagaacgct tgctcactca
    26941 ttgttccttc agcagtaggc atagcaattc catattgttt attctcttta tctgtgaaat
    27001 gttgagcaat ttttaaaata tcatcccaat tttctggttc tgaaaaacca gcttctgata
    27061 atttttcttt gtcataccaa ataccttgaa cccagccgct aattggtgca gcaatatagc
    27121 tttttccatc ttctgaacga acaaggtttt tggctccgtc ataataatta tcttctccag
    27181 cttcctcgat aacgttttgg actgccgtct gatcaatcag ttcatcttta tccatcactt
    27241 tagcaaaatc ctgactgact tccattactt ctggtaattt accggaacga gctaacgtaa
    27301 cgatttttgt attgaacgct gattcttcta ccggcacttg cttgattttg atgtctggat
    27361 tttctttttc aaaatcagca accagttcat tgatcacact taatcgttcc tgttcgacag
    27421 aagagtgcat gaattgaatc gttgtctgtt gtgattcgtt agagctttga ctttcaccac
    27481 aagcagtaag aagaaatcca gtagctagca gacaggtagt aacaataatt tttttcattt
    27541 ttttccacct cttattttat tattttcagc cacatatatt catacggctg gaatatcaac
    27601 tttcgttctt gactgcaatg gataatttgt ccagaaaaca ggtctaggta atctcctttt
    27661 ggtaaaagat aacctgctga ttgattggaa aaattatgga taactaagac tttctcttcc
    27721 ttcgcttcgc gaataaaact gataaaagaa tctgctgagt ccagtaagta aatcaaacta
    27781 ttcggatgga aggctttttc tttttttcga atagatagca tctgggtcaa ttcaccatat
    27841 actgctgttc ttaatggatc tgtctgcaac tctttctcaa tatctgctaa caaaaatttt
    27901 tgccgattga tttttcgatt ctctcctgtt ttttctacgc ctttgtaatc atttcgactt
    27961 cccagcacac tttgaatata aattgccggc acgcctggta acgttaccaa aaatgaatga
    28021 gcagctaaaa agcgtttgct tctccattcc gtcgtatctg ttggagaact taacgcatct
    28081 agatacgtag cgtttatctc atatggactg gtcgttccat ctgggttttt cttgtagttt
    28141 actcgggcac cctctttctt cagctgttcc actaattcaa ggatcgtttt ttccggcaga
    28201 atacctcgta ccggattcaa tccgataccg tcatgggagg ctaaaaaatt aaaaaaagtt
    28261 gtttttttcg atgcgaaatc gatggttttt aaccattctt tcaacttact tgtattaccc
    28321 gaacgaatcg cttgaagggt caaaggtggt agcgaaaact gatagaccat ctgtgcttca
    28381 ttctcgccat tcccaaaata actgatatta tctttgtgtg gcacatttgt ctcagtgatc
    28441 aataccgttc ctggagctgc ttcatcagcg attgcacgga ataattggat gattttatgc
    28501 gtttctggca ggtgtataca agaagttcct agttctttcc ataaaaatcc cacagcgtcc
    28561 aagcgaataa atgaagcgcc tttttctaag taaaacaaaa gaatatcgat cattttcaat
    28621 aaaacttctg gatttttaaa attcaagtct acttgatctt cgctaaaagt cgtccatacg
    28681 tgtttttctt tcccgttttt gtcaatgaac gttgtaagta acgggctggt ccttggtcta
    28741 gtcacgctgc ttgtatctgt atccagtggc aaatcaataa aaaaatcttt gtacgtatca
    28801 ttcaagttta aatattcctg aaaccaagta ctttcggcag acatatgatt gcagacaaag
    28861 tcgaacatta accgtgtttc gcttctcatt tcttctatat cttcccatgt gcccaaacgg
    28921 tcgttgattg cctgataatt tacaacggag aaaccatcat cagatgtata tgggaaaaat
    28981 ggcaagaaat gtacaactct aaatgtatct gccaaatact tttgataaaa tttcttaaat
    29041 gtacgcaaag ttggttgctg ctcttcaaaa aattgatccc cataagtaat caagaaaata
    29101 tcttcttcgt cccaatgcag tttgcctgcc tggcctttct tctgctgata aacactgact
    29161 ttttgttcaa tcatagaggc ggttttctca gacaaatctg agtcgcgata aatcgcttgt
    29221 aaaagttttg tatacatcgg attccccttt cttttttggg agcgttccca acgatttgat
    29281 catattatgg aaaacgctta ctgtcaatag cattttttta aataattttg atatacacaa
    29341 aaatacaaat aagaaagctt atgtatcaat aattaatagc ttcttaaaaa aatatggtct
    29401 ctcatgatca tgcaagctat tcctaaattt tcaaaatcat agacaaaaaa gaatgtctat
    29461 tgtactatgg aattattcta aaacgctccc aaaaaggagg tgcatataaa attgaaacct
    29521 actatttatg acattgcgaa aaaagctaat gtctcaaaat caactgtctc cagagtatta
    29581 aataaccagc caaatatctc tgataaagca aaagcaagtg tacttcaagc aatcaaagaa
    29641 ttgaattatg aaccgagcaa aattgcaaga ggactgtcag gaaatggttt tgacgcgatt
    29701 ctagcattat ctcatcgtac ttctcatacg acctatggca atcctttttt ttcagatgtt
    29761 attcaatcca tttctgccgt ttctgaacaa aataacttcg acttgattct acaaacggca
    29821 aaaacaccag aagaagagct agaaaaatgc gcgaaaaaga tccaagaaaa aatgatccga
    29881 ggaattatta ttttaagctc tacgatggat gaaacacttc tttttgaatt ggatcaatac
    29941 aatattccta ttgtggtaat cggaaaagtc ggaaacgact acacgaacat ctactcagtg
    30001 gacacggata atttccagga tagttacgat ttggtggaaa cactgatcaa gaatggacac
    30061 cgtcatatcg gctgtctcca tgctccgaca gaagtttatg tatccaatga tcgtctcaat
    30121 ggttaccgtc aatgcttatt tgatcaccac ctagatatcc gtaatgaatg gattatagac
    30181 ggcggctttc gcttagaaga tagcatggca gcaatgaatg atttaatgaa gctacgagaa
    30241 agaccaactg cgattttttc taccgatgca ttaaaatcat tgagtattta caaagtggca
    30301 gaacaatctg gaaagcagat acctgatgat ctttcgatcg caggattcag tgatccctta
    30361 ttgtcctccc tattttcgcc acagttgact cggatagaca ttccgacaaa tcagttagga
    30421 atcaaagcca cagaactttt attccaacta atccaccacc aataccctga agaaaaaaga
    30481 atcattcttt caaccgagat tactctcaca gattcgatcc aacaacaaga aatgtagaac
    30541 agaattataa aagaacagaa acactgagga taagtcagtt actctgttct tttttcaatc
    30601 actcatccct cgttaccccc tcccggtatt ttagcgaatt tttcttattt tccatctgtt
    30661 ttagatagct gtggataact ataatgtttg tgttaaacta ttttttccac agggaagaaa
    30721 aaactatttt taaccacgtt gtgtataagt ttttatagtt cgttttttta aacacattta
    30781 cccttatttc aatccatgtt atttggggat acttatctct aaaacataaa tagaataaca
    30841 gacatgtcta ctggttttgt tttattcgag gaattattca ataatagcta gcaaaatatt
    30901 aaaaataacc gctctatctt cccatcaatt tattttgcat tcaaaaaatg atctatcttt
    30961 acttttgttg attgacttct cttggaagat gatcgttccg ataccttaat tggatacgaa
    31021 ccgatgttgt taagatcctt tcccactttt cttctagtta gacaaattat tttagacaaa
    31081 ccaaaaaaga ggttgtgaca ataatttgtc acaacctctt ttttaaaata tctattttgt
    31141 ttgattgttc attgcgtctt ctgcagccat ttgcgcttca atatctgaaa tactgtagac
    31201 attttcgctt gctacaccga cttcttttgg ttccatgtca cgataacgtt gcataccagt
    31261 accagctggg atgatcttac ctataataac attttctttc aaaccaagaa gaggatcttt
    31321 cttaccgcgg atcgcagcat ccgtcaagac acgagttgtt tcttggaatg atgcagcaga
    31381 taagaaacta tttgtttcta atgatgcttt tgtgatacct agtaagacag gtcgagaagt
    31441 tgcaggaacg cctcctgaga ctagcgtatt gtagttttga tctttaaagt ctgcgatgtc
    31501 taataatgta cctggtaaga tatctgtatc acctggatcc attacacgaa ctttacgcag
    31561 catttgacga accattactt cgatatgctt gtcgccgatt tctacccctt gcatacggta
    31621 aacacgttgt acttcacgaa gcaagtagtt ttcaacagat aatacatcgc gaacttgcaa
    31681 caattgtttt ggatcgattg atccttctgt caatggtgca ccacggtgga tcatatcgcc
    31741 ttctgctact ttcatacgtg ctgtataagg aacagtatac gtacgtgtat ctgtttttcc
    31801 tttgattgtt acttctttgg tacgtgttgc aggatcttct gagatatcga tgacatcccc
    31861 tgttacttct gtgatcactg cttgcccttt cggattacgt gcttcaaaga tttcttggac
    31921 acgaggaaga ccttgagtga tatcgtctcc ggcaacccca cctgtatgga atgtacgcat
    31981 cgtcaactga gtaccaggtt caccgattga ttgagcggcg atcgtaccaa ctgcttctcc
    32041 gacttcaacg tcagagccag ttgcaaggtt gcgtccgtaa caatgtttgc agacaccatg
    32101 ttttgtatta catgtgaaga cagaacggat tgtcactgtt tcgacacctg catcaacgat
    32161 ttgttttgcg atgtcttcgg aaatcaattg gtttcctgca atgatcaatt catttgtttc
    32221 aggatgacgt acttctttac gggtgtaacg tcccactaaa cgatcttcta atgattcgat
    32281 gatttcattt ccctcgcgga tggcttggat ttcaagacct cggtcagtac cgcaatcttc
    32341 ttcacggatg attacatctt gggccacgtc aaccagacga cgagtcaagt aacctgaatc
    32401 ggcagtcttc aaggctgtat cggtcatccc tttacgagcc ccgtgagttg agataaacat
    32461 ttccaagacg gatagtcctt cacggaagtt cgaaatgatt ggcaattcca tgattcgacc
    32521 attaggagcg gccatcaaac cacgcattcc ggcaagctgt gtaaagttgg aaatgttacc
    32581 acgagctcca gaatcagaca tcatgaagat tggatttttc gcttccaaac cttccatcag
    32641 tttttgttgg atgctgtctt ttgcagcatt ccaaacagca atgacacgtt cataacgttc
    32701 gtcatctgtg atcagaccac gacggaattg ttttgtaata gtttcaactt gtttatgggc
    32761 attttcaatg atttcttgtt tttcattcag tacactgatg tcagcgatcc ctactgtgat
    32821 accggcatgt gtcgaatgtt tgtaccctaa gtctttcata cggtcaagca tcttagaagt
    32881 ttcttttact ttgaatcgtt tgaagacttc tgcgatgatg tttcctaagt ttttcttctt
    32941 gaacggtaat actaattctt gctctttgat atgtgcagga atatcagtac cagcttcaac
    33001 aaagtatttg tccggtgttt ggacggtcaa gttgaagtct gttggttcat tcagataagg
    33061 gaattcagga ggcatgatct cgttgaagat gatcttacca actgttgtga tcatcgtacg
    33121 ttctttttgc cattcagtaa atggtttttc acctaatgag ttagggttca caccgatacg
    33181 tgaatgtaaa tgaacatatc cgttgcgcca tgcgataacg gcttcgtttt gatctctgaa
    33241 gaccattcct tcgccttcgc gtccttcttc ttccattgtc aagtagtagt tacctagaac
    33301 catatcttga gaaggagtaa caactggttt accatcttta gggttcaaga tgttttgagc
    33361 agctaacatc aacatacgtg cttctgcttg tgcttcttca ttcaatggaa cgtggacagc
    33421 catttggtct ccatcgaaat cggcattata agcttcacat acaagtggat gcaaacggat
    33481 tgcgcgtcct tgtactaaaa ctggttcgaa tgcttggata ccaagtcggt gaagcgtagg
    33541 tgcccggttc agcaatactg ggtgttcctt gattacgtct tctaaaacat cccatacttc
    33601 gtcttcttga cgttcgattt tacgtttcgc atttttgatg tttgaagcta gttcgcgttg
    33661 aacaagctca cgcatcacga atggtttgaa taattcaatg gccatttctt ttggaagtcc
    33721 acattggtac atcttcaaga aaggtccaac aacgataacg gaacgacctg agtagtcgac
    33781 acgtttacct agcaagtttt gacggaaacg accttgtttc cctttcaaca tatgagaaag
    33841 agatttcaat gggcggttac ctggtccagt aactggacgt ccgcgacgac cgttatcgat
    33901 caatgcatct actgcttctt gcagcatacg tttttcattt tgaacgatga ttccaggtgc
    33961 attcaagtct aacaaacgtt tcaaacggtt attacggttg attacacgac ggtaaagatc
    34021 attcaagtca cttgttgcaa aacgtccacc ttctaattga accattgggc gtaaatctgg
    34081 tggaataaca gggataacgt ccataaccat ccagcttggt tgatttcctg aagcgcggaa
    34141 tgcttctaaa atatccaaac ggcggattgc acgtgtacgt ttttgtcctt gtgcagattt
    34201 caattcttct ttcaattcgg ctgcttctgc atctagatca acattatcaa gtaattgttt
    34261 aatcgcttct gcacccatag cagcttggaa ttcttgtcca tattgttcac gtttttcgcg
    34321 atattcgcgt tctgtcaaca attgtttttt ctctaaattc gtatttcctg gttcgatgac
    34381 tacatatgaa gcaaaataaa tgatttcttc caaagcgcgt gggctcatgt ctaatacaag
    34441 acccatacgt gaaggaatcc ctttaaagta ccagatatgt gaaacaggag ctgctaattc
    34501 aatatgtccc atgcgttcac ggcgaacttt cgaacgagta acttccactc cgcatcgatc
    34561 acaaacgatt cctttataac ggatacgttt gtattttccg caggcacatt cccagtcttt
    34621 tgtaggacca aaaatccgct cacagaacaa cccttcgcgt tcaggtttta aggtacgata
    34681 gttaatcgtc tcaggttttt ttacttcacc gtaagaccag cttctgattt tttcgggaga
    34741 agccaaacct atttgcatac tttcgaattt atttacatcg atcaaaaggg gttccctcca
    34801 tttcatttaa tggcaaaccg caagacggct gatcttcgac cgccttgcag ctcatagacc
    34861 ggattagtct aaattatctt ctgcggtttc aaagttttgg atgacatcgt ctttttcatc
    34921 ttccacttgt tcagcagctt tcttttctaa ttctttggca gtttgctgtt cggcaaattt
    34981 tgtcaaagca tcaacagtga tcaaatcgtc gtcttcatcg tccatgtcgc gaagttcgat
    35041 ctctgtttct tcgatatcca agacacgcat gtccagacct agtgattgca attctttcac
    35101 caatacgcgg aatgattccg gtacacctgg ttttggaatt ggttcaccct tgacgattgc
    35161 ttcgtatgtt ttcacacgtc cgactacgtc atctgatttg tatgtcaaga tttcttgtaa
    35221 agtataagcc gcaccgtaag cttccagtgc ccatacttcc atttcaccaa aacgttgtcc
    35281 accaaattga gctttacctc ccaatggttg ttgtgtaacc aatgagtaag gtccgattga
    35341 acgtgcatgc aatttgtcat cgaccatgtg agcaagtttg atcatgtaca tcacaccgac
    35401 agacacacgt ccatcaaatg gttcacctgt acgtccgtcg tacagaacag ttttcgcatc
    35461 gctggccata ccggcttcac gaactgtttc ccatacgtct tcatcacttg caccatcaaa
    35521 tactggcgtt gctacgtgga tacctaactg acgtgcagcc atacccaagt gtaattccaa
    35581 tacttgcccg atgttcatac gtgaaggcac ccctaaagga ttcagcatga tatcgattgg
    35641 tgttccatca ggtaggaatg gcatatcttc ttccggcata atacgggata caaccccttt
    35701 atttccgtga cgaccggcca ttttatcccc ttcatggatt ttacgttttt gaacgatata
    35761 aacacgaact aacatgttta cgcctggtga caattcatct ccagcttcac gagtaaagat
    35821 tttcacatcg tgaacgatac cgccgccgcc atgtggtaca cgtaatgatg tatcgcggac
    35881 ttcacgagct ttttcgccaa agatcgcatg caatagacgt tcttctgcag ataattctgt
    35941 tacccctttt ggcgtgactt tccctacaag caaatcgcca tcttggactt ctgcaccaat
    36001 acggatgata cccatttcgt ctaaatcttt taatgcgtct tccccgacat tagggatttc
    36061 gcgtgtgatt tcttcaggtc ctaattttgt atcgcgggct tctgattcat attcttcaat
    36121 atggatagaa gtgtatacgt catcttttac caaacgacgg ctcatgatga tcgcatcttc
    36181 atagttgtac ccttcccaag tcatgaaacc aactaaaacg ttttggccta gagccatttc
    36241 gccttgttcc atagatggtc cgtctgccag agtatcccct ttttcgactt tctcacccaa
    36301 atgaacgatt ggacgttggt tgtagcttgt tccggagttt gaacgacgga attttgttac
    36361 atcgtattta tctaatgcac cgttgtcgcg gcgtacgcgg atttcagaag catcaacgta
    36421 ttcaacgaca ccatcatgtt tacataacaa agcagctcct gagtcatgcg ctgatttgta
    36481 ttccatacca gtaccaaccc atggtgcttg aggattgatc aacggcactg cttgacgctg
    36541 catgttggca cccatcaagg cacggttgga gtcatcgttt tccaagaaag gaatacatgc
    36601 tgtcgcaacg gcaactactt gtttaggtga tacgtccatg tagtctactt tatcaataga
    36661 tacttctaag ttttcacttt gagcacgagc cataacaacg tcttgagcaa atgttccatc
    36721 ttcattcaat gggctgtttg cttgggctac gatgtaatgg tcttcgatat cagctgtcaa
    36781 gtagtcgatt tggtcagtaa cacgacctgt ttcacggtct acacgacgat aaggtgtttc
    36841 gataaatccg aatttattta ctttcgcata actggacaaa ctattgatca acccgatgtt
    36901 tgggccttca ggagtttcga tcggacacat acggccatag tgggagtagt gaacgtcacg
    36961 aacttcataa ccggcgcggt cacgagtcaa tccgccaggt cctaaggcga aaagacgacg
    37021 tttgtgtgtc aattcgccaa gagggtttgt ttgatccatg aactgtgaca actgagaaga
    37081 accaaagaat tctttgatac ttgccacaac tggacggata ttgatcaatt gttgaggtgt
    37141 caatgtttca gtatcttgga tcgacattct ttcacgaacc acacgttcca tacgtgctag
    37201 cccgatacgg aattggtttt gtaaaagttc accgactgaa cggatacgac gatttcctaa
    37261 gtggtcgata tcatcgacat tgccgatacc ttccatcaag ttcaagaaat agctcattga
    37321 agcaatgatg tcggctggac gaaccgtttt tacagctgct tctggatagc cgtttccgat
    37381 cacgtttact tcacgttcag ggtctcttgg tgaaaatact ttgatgactt ggacagtcat
    37441 tggatctgtg accacaccgt cttctgatgg atagtaagtc actgaattta ggccattatc
    37501 aatgaaagga gctagtgttt ccatgacttg gtgagtcaga actgttcctt tttcaacgat
    37561 gatctcgcct gtttctggat caactaatgt ttcagctaat gtcagattca atagacgtgt
    37621 tttcaaatct aattttttgt ttactttgta acgaccaacg tttgctaagt cgtaacgttt
    37681 tggatcgaag aaacgagcat tcagcaagtt acgtgagctg tctgctgttt ttggttcgcc
    37741 tggacgcaaa cgttcgtaaa cgtctttcaa accttcttct gttcttgagt cgcttgcgtt
    37801 tttatgcaag tctttttcga ctgtattgcg taatgtttcg ctgtcgccga agatttcaaa
    37861 gatcgtatca tcggaaccaa atcctaacgc acgaactaat acggttaaag gaatcttacg
    37921 tgtacggtcg atacgtacat aagagatgtc ttttgcatca gtttccattt ctagccaagc
    37981 tccacggtta gggataacag tagaaccgaa tccttctttt ccgtttttgt cgacttttcc
    38041 atggaaatag acacctggtg aacggactaa ctgagaaacg attactcgct ctgccccgtt
    38101 gatgatgaat gttccttgtt ctgtcattaa tgggaaatca ccgaagaata cttcttgtgc
    38161 tttgatttcg ccagtctcgc ggtttgtcaa acgcaatgtt acatgtaatg gtgcagagta
    38221 gtttgcatca tgcgcacgag cttctgctac tgtatacttt ggttctttca attcataatc
    38281 tacaaattcc aaagatagat tgccattgaa gtcatcgatt ggcaaaatgt cttcaaacat
    38341 ttctctaagt ccctcatcta agaaccattg gtaagagtct gtttgaattt cgatcaaatt
    38401 tggtaattcc aacacttcac tgattcttgc gaaacttcta cgttcgcgat gttttccgta
    38461 ttttactacg tgtccagcca agctcttcac ccctctaaaa tgtcattcaa aaagactacc
    38521 cgatcaattg ttacaataat atttcaaata ttatttttag gtaacaacag acattttttg
    38581 cggcttttag gcaaaaaaaa accaaaaata gaacattctc ttgaaacctt acttcgtgag
    38641 cttctacttt tgtttcctta tattaaagcc gaaacggaca atatttcgtt tctgcctttt
    38701 cttcatcaga tagtttttgc aacttcatat actacactta ttttctataa aagtcaacac
    38761 ttcctggcgt ttcttctgct ttttcgcaac attttcttaa tgttttcaat tttatgtttt
    38821 caattatctg acaattctta attgacagac ctttttatct cggttatact ttagaaaatt
    38881 cattttgtgg aggaacttct atgcgaacca acatcaacca aatcgcacca acacaactga
    38941 ataactttta ctttagctac tttagatagg tttgtattca tcatgatgga tacaaacgtt
    39001 aaacgacagt ttgtatctat gatggctaaa gaactttgta ttgcagcaaa aagccacgta
    39061 gacaaaatgc taagtggctg agcagtgaaa atacaaagta aaagtatcaa gcattctact
    39121 ttttcaattt attttccgac ttttcaatcc atttggacat tttgtctgaa tggatttttt
    39181 gtttcccaaa attaaggagg aaaaagaaat gaaaaaaaat ataatcatcg gattaggcgc
    39241 tgccctgcta ctagctttag gaggttgcgc acaaaaagac aattccgcag aggcatcaga
    39301 tggacaaaaa acaattggcg tattgcaact tgtacaacat aactcgttag atgctgccta
    39361 taaaggattc aaagaaggat tagcagaaga agggtataaa gaaggcgata atctaacaat
    39421 cgattatcaa aatgcccaaa acaatcaaga caacctgaaa agtatgagtg agaaactcgt
    39481 caaagaagat cctgatttgc tacttggaat cgccactcca gcagcacaat ctttattaaa
    39541 tgaaacaacc actatcccga tgactgtcac agcggtcaca gacttggaac aagcccattt
    39601 agtcacatcc aatgaaaaac ctggcggcaa tgtgactggc acgacagata tggtgccaat
    39661 cgaaaaacaa atcggcttac tgttaaatat cgtgccagac gccaaaacaa tcggcatcat
    39721 gtataacaac ggtgaagcaa actctaagat ccaagctgat ttggcagaaa aagaattgaa
    39781 aaaagcgggc gtcaaagtca aagtactgac agcaaattcc acaaatgatg tccaacaagt
    39841 gacgaaaagt ctagctaaag atgtagatgg aatctatatt cctactgata acacgttcgc
    39901 aagtgcggca agtgttgtcg gtgaagtcgc aaaagaaaca aaaacacctg tcgttgctgg
    39961 cgcagttgat caagtcaaag acggcggtct agcaacagta ggaatcgact acgaaagctt
    40021 gggcaaacaa acagggatca tggcagcaaa aatcttagac ggcaagaatc caagtgaact
    40081 tcctgtcgaa acagcgaatg atttggaact gtatgtcaat aaagacatgg ccaaagcatt
    40141 aggcatcaat ccagacagca tcaaagaagc tgaataaaac acaggaggat tctcatgaca
    40201 aatttgctct ctcttttctt atcatctgca tcgcaagggg tcttatgggc cctacttgcg
    40261 attggtgtat acgtcacttt ccgtatcttg gacattgccg acttgactgc tgaaggaagc
    40321 tttcctttag gtgcagggat cgcggcagta agtattacaa atggctatca tccattgaca
    40381 gcttgtcttc taggcttttt agggagtgcg gcagcagggc ttgtttccgg actgcttcac
    40441 acaaaattga aaattcccgc ccttcttgca gggatcatca ccatgactgg tttatattct
    40501 gtcacatccc gtgtgatggg tgcgccgaac atctctttat tgggtcagcc aacgatcttt
    40561 cattgggtcg agtcattcgg cataacaaaa gacaacgctg tactgatcgt cggtctgctt
    40621 tttgctttga tcgttgtatg tttacttgtt ttgttcttac gtacagaaac aggacttgct
    40681 attcgtgcaa ctggcgataa tctggcaatg agcgaagcaa acgggatcaa cacagataat
    40741 atgaagatca tcggttatat gatttctaat ggatgcattg ctctttctgg ctccttgctt
    40801 gcgcaaaaca acggctttgc tgatttaaat tctggtattg gaacgatcgt aattggactt
    40861 gcttctatta tcatcgcaga agttttgtta cgtaaccagc cactatttct ccgtctcttg
    40921 actgtcgttt taggtgcggt catttatcgt tttattttag cgttagtctt cgaactgaat
    40981 gttgaaccaa gtgattcgaa acttgcttct gctttcgtgc tagtgatctg tctttctttc
    41041 ccgcagatcc agcaaaaatt ccatttacct caaaaaaaga aaggcggtag tgtcaaatga
    41101 atgacgtctt aacattggaa aatctccatc atacctttga aaaaggaacg atcaacgaaa
    41161 atcatgtcct gaaaggcatt aatctttcct tagatcccgg cgacttcgtg acgatcatcg
    41221 gtggaaatgg ggctggtaaa tctactttgc tgaacagcat cgccggtaca ttttctgtcg
    41281 atcagggtca aattttattg aatggaaaaa atatcacgaa aaaatctgtt gtcgaacgtt
    41341 cgaaatccat cagtcgcgta ttccaagatc ctaaactagg gacagccgtt cgtttaacgg
    41401 tagaagaaaa tcttgctctt gctatgaaac gaggaaaaaa acgcggcttc ttccgtggtg
    41461 tcaaaccaca agaccgaaca tttttcaaag accagctggt tcggctaaat ttggggttgg
    41521 aaaatcgttt atcctcagaa atcggtttgc tgtctggagg acaacgtcaa gctattacgt
    41581 tattgatggc cacattacag cgtccagaac tgatcttatt agatgaacac actgcagcgc
    41641 ttgaccctgc tacttccaaa acggtgatgg aattgacaga aaagctgatc actgagcaga
    41701 atctcactgc ttttatggtc actcatgaca tggaagacgc gatccgctat gggagtcgac
    41761 tgatcatgct gcatcaagga aggatcgtcg tagatatcca gcaagaggaa aaacagcagc
    41821 tcacagtgcc ccaattatta gcgttgttca aacaaaacag cggcacggca ttaaaagacg
    41881 atcaagtact tttatcttca taatcagaaa gaggatggga caaaaaatga acgcccaccc
    41941 tcttcttttt tctctttcct tctttcgttt ttgctttatg tatcaaccgt tgtttcttcg
    42001 aaaactattt tgttctctcc ttcttcctga tagaatggat gggaaaggag cttgatgcca
    42061 tgacaacgaa agacaaggta cttcaattat tgaaaaagac accagatttt ctttccggag
    42121 aaaagttggc acagcaactg gaagtttccc ggacaagtat ttggaaagcc atcaaagaat
    42181 tggaaaaggc aggctatcgt tttgagcacg ggcctacagg gtatcgttac ctgccctctg
    42241 acgtactaga tgcaaaagaa atccagcaag agctacggtc gtttattcct gatttgaaag
    42301 tacaaacgat gttgacttct gaatctacga tgaaagatgc caaactggca gcagctcaag
    42361 gagattctgt ttcgaagtta tttgttgctg atacacaaga acaagctcgt ggacgttttg
    42421 gacggccttt tttcgctgaa cctggacgag gaatctacat gagtctcttg ctccatccag
    42481 acaaacggtt tgatgaattg cctcaatata cgatcatcgc agccagtgcc tgtgtgaaag
    42541 ccattgaatc tgtaaccggt cgttctgctt cgatcaaatg ggtcaatgat atctacatgg
    42601 atggaaaaaa agtctgtggg attttatctg aagcagtcag tgatatggaa agcggcagga
    42661 tcagtcatat catcattggg atcgggctta atttttctgt tcctcaaaat cattttccag
    42721 ctgatctcca agaaaaagcc atctctgtct ttcccgacgg acaagctagt gtcacaagga
    42781 atcagctaat cagcaaaatc tggcaagaat tgttcactta tctttctcac ccagaaaaag
    42841 cgttggactt ctataaagaa aaatcattcg tattgggaaa aaccgtgtcg ttcaatcaaa
    42901 aaggaacgac ttatgtcggt cttgcaaaag aaatcggtga tcatggcgaa ctgatcgtcc
    42961 aaacaaatga acagaagatg agtttgtctt ctggcgaaat cagtctcaca tctatccgta
    43021 cgcaataatt atcagatttc acaaaaggac acctgatctc atacagtgtc cttttttctg
    43081 aattctcttc aaaagactct ccttattcta tcagctgaca gtttctctat cctctagaaa
    43141 aaggtattct aaaaatatct ataaagcatg gtacactttc tttaaatgaa tcaatgcaaa
    43201 aaacaagaga gtcatcagtt tacacgatca aaagagatag caggccgctt cctttttcaa
    43261 tcttatagat agaccatggg taacgataaa aacaaaaaag aacttgcgac ttattttgcc
    43321 gtaagttctt ttttagctag tgccttaatc tcttaatccc aacaaacgtc tcgcatagat
    43381 cacctgacca gagtgcatag cagcatcatc aataatagaa acgagacgca ttcctcgtgt
    43441 gactggtggt gtccagttct cgtcaattac ttcatctagc tcggaaggtt ccagccttct
    43501 taagtaagaa atagcaaaat cagcagctcc tcgcaagtat cctagcagat cttctatttg
    43561 attagcttgg atctgctttg cttgttccag actatgcttc caatcttgtt cgttatctgc
    43621 tatcgtcatc ggaaaccggc tttcccagtc ttgactatgc caaattggag aagttcctgc
    43681 taaatcagca atctggaaat ctaattctcg agcggtatgc caagccagcc aagtcattga
    43741 tttgatctgc ggggctctat cttccactgg aaaacgattg gcctcctcaa tagagacgcc
    43801 ttcaaacaaa cgttcaaacc gatcgtatgc ccgatccaca ctctcgcata gcatatctaa
    43861 ataatccatt tattttcctc ctttttattt atcctactta ctttttccta attctaggat
    43921 acctacttat atgttactac acacccttat tttttacact ttaacagtca ccatcatcaa
    43981 tagtttggag attgaaagaa aaagatagtg tcgaactatc aattgaacaa gaagcaacaa
    44041 tatgaacgtt tcattaatat tctttaaata aacaatgatt tttcaaacga acagtttaag
    44101 actaggagaa aaagagtata ataggaaaat gtttgaaagg aaaggaaggg gaaaaatgaa
    44161 aaaaagggca agtttactag tcctagttgc tttgttgttc aatatctttt cgtatggtgt
    44221 ggccgtttca gcggaaacat acattcctaa agaccctggg aatatttata atgatctaac
    44281 tggtaactat ggcttgttag gaattgctag tcaattccac gtatttgcta aaaataagac
    44341 aactgtgaat gcacatacag acggaaatat agcaacacat gaacttgatg caaaaaataa
    44401 ttttggtaca gagcttcatg aaggtttatt gaaccaagaa ataaattata tacaaaaaac
    44461 tgattctttc gctaattctt caggcatacc tacaggtagc acaagaatga ataaatttgt
    44521 cgttggcagt aacgtggatg tagcacttca agatggtcat cctacagtca atggatccag
    44581 gcttgatcac ttaactccag atgattttta taaagatcgt gctgggcatg aatatattga
    44641 tttcgagcag gaatttgcta aattgaatgt agcagcaaat gatcttgcaa cgatcactcc
    44701 agctaaaaca tatactgctg cagattttcc agacatgaac aatcggacaa tcgatttaac
    44761 tgatttatca gataccgggt ttttattggt aaatatcgat gcagaagtgt taacgatgaa
    44821 tacgccactt caaatcatta atccaaatga tcaagtagtt gtatttaatg tcatcaacag
    44881 ttcttctgca ttgaacgtac agtcaccaat caaatacaat gatcgttcaa atcatgaaac
    44941 agaagatttt tcggatgcga atatctcttg gaattttgga aatgagatga ctgatttgac
    45001 aatcagtgct ccttttcaag gaacaatcct tgcgcctaat gctactatcc gcattactca
    45061 aaaccaagac ggaacgatta taggaacaaa tgtgatttta gatgcagcta ccaatcgttg
    45121 ggatcctaac gaaatattta tcagcgacaa tggtacagat acgacagaca caagcgacag
    45181 tacagataca tctaccacaa gtgatagctc agattcatca acttcaagcg acagtacaga
    45241 tactacctct accacaagtg atagcac
//
LOCUS       DAZKCW010000023        43107 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000023 DAZKCW010000000
VERSION     DAZKCW010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.023"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            637..1602
                     /locus_tag="ACG84Z_001317"
     CDS             637..1602
                     /locus_tag="ACG84Z_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6017 domain-containing protein"
                     /protein_id="HFP9162169.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            1624..1836
                     /locus_tag="ACG84Z_001318"
     CDS             1624..1836
                     /locus_tag="ACG84Z_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFP9162170.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            1911..2387
                     /locus_tag="ACG84Z_001319"
     CDS             1911..2387
                     /locus_tag="ACG84Z_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HFP9162171.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            2384..4192
                     /locus_tag="ACG84Z_001320"
     CDS             2384..4192
                     /locus_tag="ACG84Z_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFP9162172.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            4269..4484
                     /locus_tag="ACG84Z_001321"
     CDS             4269..4484
                     /locus_tag="ACG84Z_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family mobile element protein"
                     /protein_id="HFP9162173.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            4576..5439
                     /locus_tag="ACG84Z_001322"
     CDS             4576..5439
                     /locus_tag="ACG84Z_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB6/TrbL-like conjugal transfer protein,
                     CD1112 family"
                     /protein_id="HFP9162174.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            5476..6012
                     /locus_tag="ACG84Z_001323"
     CDS             5476..6012
                     /locus_tag="ACG84Z_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MT-A70 family methyltransferase"
                     /protein_id="HFP9162175.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            6026..6448
                     /locus_tag="ACG84Z_001324"
     CDS             6026..6448
                     /locus_tag="ACG84Z_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HFP9162176.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            6378..8777
                     /locus_tag="ACG84Z_001325"
     CDS             6378..8777
                     /locus_tag="ACG84Z_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4-like conjugal transfer ATPase, CD1110
                     family"
                     /protein_id="HFP9162177.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            8809..10800
                     /locus_tag="ACG84Z_001326"
     CDS             8809..10800
                     /locus_tag="ACG84Z_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFP9162178.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            10823..11074
                     /locus_tag="ACG84Z_001327"
     CDS             10823..11074
                     /locus_tag="ACG84Z_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HFP9162179.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            11064..12293
                     /locus_tag="ACG84Z_001328"
     CDS             11064..12293
                     /locus_tag="ACG84Z_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD1107 family mobile element protein"
                     /protein_id="HFP9162180.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            12290..14371
                     /locus_tag="ACG84Z_001329"
     CDS             12290..14371
                     /locus_tag="ACG84Z_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HFP9162181.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            14520..18440
                     /locus_tag="ACG84Z_001330"
     CDS             14520..18440
                     /locus_tag="ACG84Z_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodL domain-containing protein"
                     /protein_id="HFP9162182.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLPNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            18441..19385
                     /locus_tag="ACG84Z_001331"
     CDS             18441..19385
                     /locus_tag="ACG84Z_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162183.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            19389..19592
                     /locus_tag="ACG84Z_001332"
     CDS             19389..19592
                     /locus_tag="ACG84Z_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HFP9162184.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(19892..20128)
                     /locus_tag="ACG84Z_001333"
     CDS             complement(19892..20128)
                     /locus_tag="ACG84Z_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162185.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(20311..20682)
                     /locus_tag="ACG84Z_001334"
     CDS             complement(20311..20682)
                     /locus_tag="ACG84Z_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HFP9162186.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(20679..22007)
                     /locus_tag="ACG84Z_001335"
     CDS             complement(20679..22007)
                     /locus_tag="ACG84Z_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFP9162187.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(21968..22297)
                     /gene="mobC"
                     /locus_tag="ACG84Z_001336"
     CDS             complement(21968..22297)
                     /gene="mobC"
                     /locus_tag="ACG84Z_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFP9162188.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(22555..22926)
                     /locus_tag="ACG84Z_001337"
     CDS             complement(22555..22926)
                     /locus_tag="ACG84Z_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9162189.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            23071..23256
                     /locus_tag="ACG84Z_001338"
     CDS             23071..23256
                     /locus_tag="ACG84Z_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFP9162190.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            23414..23581
                     /locus_tag="ACG84Z_001339"
     CDS             23414..23581
                     /locus_tag="ACG84Z_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162191.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            24199..24866
                     /gene="vanR-B"
                     /locus_tag="ACG84Z_001340"
                     /pseudo
     CDS             24199..24866
                     /gene="vanR-B"
                     /locus_tag="ACG84Z_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
     gene            24869..26212
                     /gene="vanS-B"
                     /locus_tag="ACG84Z_001341"
     CDS             24869..26212
                     /gene="vanS-B"
                     /locus_tag="ACG84Z_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HFP9162192.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            26383..27189
                     /locus_tag="ACG84Z_001342"
     CDS             26383..27189
                     /locus_tag="ACG84Z_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HFP9162193.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            27207..28034
                     /gene="vanW-B"
                     /locus_tag="ACG84Z_001343"
     CDS             27207..28034
                     /gene="vanW-B"
                     /locus_tag="ACG84Z_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HFP9162194.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            28031..29002
                     /locus_tag="ACG84Z_001344"
     CDS             28031..29002
                     /locus_tag="ACG84Z_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HFP9162195.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            28995..30023
                     /gene="vanB"
                     /locus_tag="ACG84Z_001345"
     CDS             28995..30023
                     /gene="vanB"
                     /locus_tag="ACG84Z_001345"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HFP9162196.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            30029..30637
                     /locus_tag="ACG84Z_001346"
     CDS             30029..30637
                     /locus_tag="ACG84Z_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HFP9162197.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(30889..31893)
                     /locus_tag="ACG84Z_001347"
     CDS             complement(30889..31893)
                     /locus_tag="ACG84Z_001347"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFP9162198.1"
                     /translation="MQRGGKSRGKAAAAGSGKQKASNGERFLKKIERTGGEAVNRLTR
                     RRKVYEAIHTLRQEKGYEIASLCALSGIPRCSYYKWLHREESASEKENTLLLEEIIRL
                     YSEVKGIYGYRRMTLNVNSRLKRNYNHKRIYRLMKSVHMQAVIRRKKKHYVILEPRVT
                     AENVLNREFTANGPNEKWLTDVTEFKLINGKKAYLSAILDLHDKSIVAYALGQSNNNQ
                     LVFDTFDRAVRANPGAHPLFHSDRGYQYTNRQFKAKLDGIHATQSMSRPGRCIDNGPM
                     EGFWGILKSEMYYLRQFHTFEELKKAIDEYIDFYNTRRLQAKLKGLAPLAYRNQTLVA
                     "
     gene            complement(31776..32459)
                     /locus_tag="ACG84Z_001348"
     CDS             complement(31776..32459)
                     /locus_tag="ACG84Z_001348"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9162199.1"
                     /translation="MSLKGKIPPEVKIQAVEDYLAIRKGSTQIREELGIRLSTFQAWL
                     RKYQTEGPAGLHPKKHVTSYPSSLKLAAVEDYMGGGGSLDAMCRKYGISSHAVLQQWI
                     TLYNQGHREFKTRRAREETDMAEKEKLSQEQKLQAVLYCLEHQLDYRRTSEQYKITYQ
                     QIYSWVKKYQEQGEAGLLDRRGRRRPPSEYSEEEKAAAKLRQLEAENRRLQMENDFLK
                     KLNELEGRR"
     gene            32905..33336
                     /locus_tag="ACG84Z_001349"
     CDS             32905..33336
                     /locus_tag="ACG84Z_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFP9162200.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
     gene            33343..33576
                     /locus_tag="ACG84Z_001350"
     CDS             33343..33576
                     /locus_tag="ACG84Z_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162201.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            34000..34200
                     /locus_tag="ACG84Z_001351"
     CDS             34000..34200
                     /locus_tag="ACG84Z_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFP9162202.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            34284..35477
                     /locus_tag="ACG84Z_001352"
     CDS             34284..35477
                     /locus_tag="ACG84Z_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9162203.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(35656..35934)
                     /locus_tag="ACG84Z_001353"
     CDS             complement(35656..35934)
                     /locus_tag="ACG84Z_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162204.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFF"
     gene            complement(36052..36312)
                     /locus_tag="ACG84Z_001354"
     CDS             complement(36052..36312)
                     /locus_tag="ACG84Z_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162205.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(36449..36862)
                     /locus_tag="ACG84Z_001355"
     CDS             complement(36449..36862)
                     /locus_tag="ACG84Z_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFP9162206.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(37318..37803)
                     /locus_tag="ACG84Z_001356"
     CDS             complement(37318..37803)
                     /locus_tag="ACG84Z_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162207.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(37942..38157)
                     /locus_tag="ACG84Z_001357"
     CDS             complement(37942..38157)
                     /locus_tag="ACG84Z_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFP9162208.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            38381..39181
                     /locus_tag="ACG84Z_001358"
     CDS             38381..39181
                     /locus_tag="ACG84Z_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFP9162209.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            39200..41068
                     /locus_tag="ACG84Z_001359"
     CDS             39200..41068
                     /locus_tag="ACG84Z_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFP9162210.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            41061..41552
                     /locus_tag="ACG84Z_001360"
     CDS             41061..41552
                     /locus_tag="ACG84Z_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFP9162211.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            41540..42094
                     /locus_tag="ACG84Z_001361"
     CDS             41540..42094
                     /locus_tag="ACG84Z_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFP9162212.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            42112..43107
                     /locus_tag="ACG84Z_001362"
     CDS             42112..43107
                     /locus_tag="ACG84Z_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFP9162213.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT        11649 a        10314 c        11039 g        10105 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaatttta ggttatcgct gaaaaccccg
      181 gaaatacggg catttcgcag gatatgagaa ctcaatttac taccaattta ctactttcgg
      241 attgagccgc atatatgctg aaccatactg ctaatacccg ccaccccaaa tacggcacat
      301 cataaattga atacgacacc gtaaacgcgg cgttcctctt tcccgtcatg ggagaacagg
      361 acgccgcttt tttatgccca aatagagaaa ggaggcgacg ccatgctatt tacttccggc
      421 cctgaccggg cgtttgaacg gctgatgcag gaaaagcccg gtttcgatca ctacgacggc
      481 ggcggggcgg acgcgccgga ggattgcggc acctgccgat tttaccgccc ggattggaaa
      541 tatcaattct gccagtttgc agagtgtccc tatcagccgg gcaagctgac cgactatgca
      601 gcggtcaaat tcacagtgaa aggagcgaac aacgctatgg cagttttccg tgtggaaaag
      661 aacaaaggct atacggtgat gtcaaatcac cacctgcgga ataagaacct gaccttaaag
      721 gccaagggcc tgctgtcgca gatgttgtcc ttgccggagg attgggacta taccctaaaa
      781 ggactgtcct atatcaaccg ggaaagcatc gacgcgatca ggacagcggt atgggagctt
      841 gaaaaagctg gatatatccg gcgtgagcag ggccgtgacg caaaaggcaa aatggccgat
      901 atggtctata ccatctacga acagccggta ttggaaaacc cggtattgga aaatccaaca
      961 tcggataacc cggtgttgga aaatccgaca tcggataatc cggcgtcgga aaatccaacg
     1021 caattaaata aagaagtaca aagaactgac ttatcaaaaa aagaaaaaat aattacagat
     1081 ggacaaagta cccattccat tcctatccca tccccgaccc ctgcccctat ggagggcgag
     1141 gcagcggcta cgccgccgga acggaaaagg acaggaaagg atgaggctgt acggatttat
     1201 cgggaaatca ttttggagaa catcgagtat gcctatctca ttcaggacag gagcattgac
     1261 cgtgaacagc ttgacgaaat cgtagacctg atgctggaaa ccgtctgcac cgcccgaaag
     1321 acaatccgtg tcgccgggga cgactaccct gccgagctgg tgaaatccaa gtacatgaag
     1381 ctgaccggcg aacatatccg ctttgtcctt gactgtctgc gggagaacac aacgaaagtc
     1441 cgcaatatca aacaatacct gcgggctatg ctgttcaacg cccccagcac catttccaac
     1501 tactacacgg cccttgtcgc gcacgacatg gcacagcccg attggggaaa gcctaaatcc
     1561 ggcctgccgg actattcctg cggcgagggc gaaagcctgt aacgagaaaa ggaggacgac
     1621 cctatgaagc agggcgcatt gatttttgac gagcgaacag accgttacga catccgcttt
     1681 gatctggccg actattacgg cggcctgcat tgcggggagt gtttcgacgt gatgatcggc
     1741 ggcaaatgga ggcccacccg cattgaaatg gccgaaaact ggtatcttgt cggcatccgg
     1801 gccgacgacc tttccggcct gcgggtgcgg atttgaccta tatctacctg cggcgtctgg
     1861 tggttccgcc ttagacgccg cttttgactt tctgacaagg agggatgcga ttgcaggaag
     1921 aagttactca aaagaccatt gccctgtcca tgaaaacggg caagctcacg gctcaagtgc
     1981 tgcaagcggc gctgaaaaag tacctgcaac accgggccaa gggcaaaaac acgctgcacc
     2041 acggccagca gagcctaaag cagcttaaaa agcatggggc tgatctctcc aacattgaga
     2101 tcaccgaggc caacattgga gcgttcaagc catgcgccaa gaaatacggc gtggatttta
     2161 ccttacgaaa agataagacc acccagccgc cccactacgt tgtgattttc aaggccaagg
     2221 atgcagataa ccttgatctg gcgtttcggg agtttaccgc caagacgctt tccaaggagc
     2281 agcggccctc tatccgcaag gttttgtccg ctgtgaagca aaaggcggcg gcccagacca
     2341 agcagcgggc caaggagaaa atcaaggaaa gggggctgga actgtgaagc ctgacgtaaa
     2401 gaaattgctg atcctgaacc tcccgtatct gatttttgtg tacctgtttg cgaaatgcgg
     2461 ggaggcgtac cggctggccg ctggtgctga cctgtcgggg aagctcctgc attttgcgga
     2521 tggttttgcg gcggcttttg ccaacccgct gccaagcctg cacctgtttg acctgtgtat
     2581 cggtatcgcc ggtgccgtga tcgtgcggct ggtggtgtac tgcaagagca agaacgtgaa
     2641 gaaataccgc aaaggcatgg agtatggcag cgcccgctgg gggacggcca aagacatagc
     2701 gccttacatc gaccccaagt ttgaaaataa tatcctgctc acccaaacgg aacggcttac
     2761 catgaccggc aggcccaaag accccaagac agcgcggaat aaaaacgtgc tggtgatcgg
     2821 tggcagcggt tcagggaaaa cgagattttt cgtgaaaccc aacctgatgc aatgctttcc
     2881 gaccacggac tatccgactt cgtttgtggt gacagatccg aaaggcactt tggttctgga
     2941 aaccggcagg atgttccagc aggcgggcta ccgcattaaa atcctgaata ccattaactt
     3001 ttccaagtcc atgaagtaca acccctttgt ctacatccat tcggaaaagg acgtgctaaa
     3061 gctggtaaat accctgattt ccaacaccaa gggcgagggg gaaaagtcag cggaggattt
     3121 ttgggtgaag tcggaacggt tgttttattc ggccctgatc ggctatatct ggtacgaggc
     3181 cccagcggag gaaatgaact tctcaacgct gctggaaatg ataaacgcca gtgaagcccg
     3241 cgaggacgac ccggagtttc aaagccccgt cgatctcatg tttgagcgtt tggagcagaa
     3301 agaccccgac cattttgcgg tgcgccagta caagaaattc ctgctgtccg caggcaagac
     3361 ccgttcttcc atcctgattt catgcggtgc cagacttgcg ccctttgaca tccgggaggt
     3421 acgcgagctg atggaggacg acgaaatgga gctggacacc atcggggacg aaaagacggt
     3481 gctgtatctc attatgagcg atacggacac gacctttaat ttcattctgg ctatgctcca
     3541 aagccagcta atcaacctgc tttgtgaccg ggctgatgat gtgtacggcg ggcggctgcc
     3601 tgtccatgta cgcctgattt tggatgaatt tgccaacatt ggccaaatac ccaatttcga
     3661 taaactcatt gccaccattc gaagccgtga aatatcggcc tctattattt tgcagagcca
     3721 gtcgcagcta aaagcgattt acaaggacgc cgccgagatc atttcggata actgcgatag
     3781 tgtgcttttc cttagtgggc gcggcaaaaa tgccaaggag atttccgatg cgctggggaa
     3841 agaaacgatt gacagtttca acaccagcga gaaccgggga agccaaacgt cccacggatt
     3901 gaactatcaa aaattaggaa aggagttgat gtcccaagac gaaattgccg tgatggacgg
     3961 cggcaagtgt atcttgcagc tacggggtgt gcgcccgttt ttatcggaga aattcgatat
     4021 taccaagcat ccccggtaca aataccttgc cgacgccgac aagaagaata cctttgacgt
     4081 ggacagattt ttgactatca cgcgccggaa acggcagcaa gtggtaacgc aggatgaagt
     4141 attcgacctg tatgaaatcg acctgtcgga cgaggacgcc gccgctgaat aaacagcggc
     4201 ttttttcatt ccaacaacaa aatcaaaaaa tcattatgag ccggaaaccg gcagaaagag
     4261 gtaaatttat ggcatttttt aattccgcag ttactacttt gcagactatc gtgatcggac
     4321 tgggcggcgc tctgtgcgta tggggcggca tcaatctgtt ggagggatac gggcaggaca
     4381 atccgggggc aaaatcgcag ggtgtcaagc agcttgtcgc tggcggcggc gtggccctga
     4441 tcggtgtcac tctggttccc ctgctgtccg ggctgctggg ctgatcctgg cctttgtccc
     4501 tgtccaaacc cttaactaat cgcctccgcg tcctcccggc cagaccggga gggcgcggga
     4561 aaggaggtgc tacccgtgat tagtgaaatc attgaagaat ggataaaagg catcctcatg
     4621 gacggtatca cgggcaacct gtccgggctg ttcgatacgg taaatgccaa agtcggagaa
     4681 atcgccgccg acgtgggacg aaccccgcag gcatggaaca gcggtatttt caatatgctg
     4741 cacagcctgt cggaaaccgt gatcgtcccc atagccgggg ccatactcgc ccttgtcatg
     4801 tgctatgagc ttatccagat gataacggaa aagaacaata tgcacgactt tgacagctcc
     4861 atgttcttcc gctggatatt caaatccgcg tttgcaatcc tgatcgtaac gaacacatgg
     4921 aacatcgtca tgggcgtatt cgacgccacc caaagcgtcg tcaatcaaag cgccggtgtg
     4981 attatcgggc agacatccat tgattttaac accctgatac cagaccttga aagccaattg
     5041 gaggctatga gcgtgggcgc tcttttgggg ctgtggttcc aaacccttgt tgtgggcctc
     5101 accatgaata tcctttccat ctgcattttc cttgtgacct atggccgcat ggtggaaatc
     5161 tatgttgtca cgtcgctggg gcctatcccc cttgccacaa tgggcaacgc ggaatggcgc
     5221 ggcatgggcc aagggtatct gaaatccctg ctggcgctgg gcttccaagc ctttttaatc
     5281 atggttgtgg tgggtatcta cgcggtgctg atacagaata tcggttccgc ttccgacata
     5341 tccggcgcaa tctggggctg tatgggctat acggtgctgc tgtgcttctg cctgttcaag
     5401 accggcagta tatcaaaggc cgtattcggg gcgcattgat cccaaaatcc aagcatacac
     5461 aggaggaact tgtttatttc aacgtacaac atcatttacg ctgacccgcc gtggcggtat
     5521 gactgcaaaa acgtacaggg cgcagcggaa aatcactatt ccaccatgag cattgacgag
     5581 ctgtgcgccc tgccggtgga acggctggcg tccaaagact gcctgctgtt tttgtgggcc
     5641 acattcccca tgctgccgga agctctgcgg ttaatcaaag cgtggggctt ttcattcaag
     5701 accgtggctt ttgtatggct gaaacagaac cgtaaaagcc ttacatggtt ttacgggctg
     5761 ggccgctgga caaggggaaa cgcggaaatc tgcctgctgg caacacacgg caagccgaag
     5821 cgtcgttctg cctctgtcca tcagtttatt atcagcccga ttgaacaaca cagcaaaaag
     5881 ccggatgtga cccgtgaaaa aatcgtagag ctggcgggcg atttgccccg cgtggagctg
     5941 tttgccagac agaaaacccc cggctgggac gtgtggggga acgaggtgga atgtgacctt
     6001 atcctgacgt gaaaggaggt gccaaatggc ttatgtaacc gtccccaagg acttaaccca
     6061 tgtgaaaagc aaggttgtgt ttgggcttac caaacggcaa ctgatctgtt tttccggggc
     6121 gctggtgatc ggcgtcccct tatattttct cacccgtgac tatcttacca acagcgcggc
     6181 ggccctgctc atggtatttg ccatgctgcc gggctttttg cttgccatgt acgagcgtca
     6241 cggccagccc cttgaagtgg tgattatgca gatcatccag tgctgcttca tccagccaaa
     6301 ggagcgtccc tatcagaccg acaacaccta caccgccctt gtgcggcaat accagatgga
     6361 acaggaggta aaggccattg tccaaaaagg aaatcccaag agaaaccgaa aaaacaaagc
     6421 tgacccgcgc ccagcgaaaa gaaattgacg cggtaatccg taaatataag ggcgacggca
     6481 ggccccacac ggcgcagcag agcatcccct acgaggtcat gtacccggac ggcgtgtgcc
     6541 gggtatcgcc cggcgtcttt tccaagtgca ttgagtttgc ggacatcagc tatcagcttg
     6601 cccagccgga cacgcagacg gctatctttg aaaaactgtg cgacctgtat aactatgtgg
     6661 acgcctccat tcatatccag ttttctttcc tcaatcggaa agttgacccg gtgcagtacg
     6721 ccaagagctt tgagatcgcg ccgcaggggg acgacttcga cgacatccgg gccgagtaca
     6781 ccggcattct gcaaaagcag cttgcaaacg gcaacaacgg catggtaaag accaaatacc
     6841 tgacattcac catcgaggcc gaaagcgtga aagcggcgcg agccagattg aagcgcatcg
     6901 gctttgacct gttaggctat ttcaagagca tgggggccgt agcccatgtg atggacggct
     6961 gggaacggct gaacctgctg catggcgtgt accacccgga cggcgagata ttcaattttg
     7021 actggaagtg gctggccccg tccggcctct ccaccaagga ttttattgcc ccgtcctccc
     7081 tgtgcttcgg caatgcaaag acattcggca tgggcggcaa atacggcgcg gtaagtttcc
     7141 tgcaaatcct gtccccggag ctgtcggacg atatgctggc cgacttcctc aatacggaaa
     7201 gcggtgtttt agtcaatctc catgtgcagg ccattgaaca gaccaaggcg atcaagacca
     7261 tcaagcgcaa aattaccgac cttgacgcta tgaagattgc ggagcagaaa aaggccgtcc
     7321 gcagcggtta cgatatggac attcttccca gcgaccttgc cacctacggc gaggacgcca
     7381 agaagctgct gacaaagttg cagacccgca atgaacggct gttccagttg acgttccttg
     7441 tcctcaacgt ggccgacacc aagcaaaagc tgaataacga cgtgttccaa gccgcaggcg
     7501 tggcccaaaa gcataactgt ccccttgtcc ggctggacta ccagcaggaa cagggccttg
     7561 caagcagcct gccgctgggc gtcaatcaga tcaagataca gcgcagcctt acgacttcca
     7621 gcgtggccgt gttcgtcccc tttgtgacgc aggagctttt tcagggcggc gcggccatgt
     7681 attacggcat caacgccaag tcccgcaaca tgattatgct ggacaggaag caggcccgtt
     7741 gccccaatgc cttgaagctc ggcacccccg gcagcggcaa atccatgagc tgtaaatccg
     7801 agatcgtcag tgtgttctta acgacgcctg acgatatttt tatttcagac ccggaggccg
     7861 aatattaccc ccttgtcaaa cggctccacg gacaggtaat ccggctgtcg cctaccagca
     7921 aggactttgt gaacccgctg gacatcaacc tgaattattc ggaggacgat aacccgctgg
     7981 ccctgaaatc cgactttgtg ctgtcgttct gtgagcttgt catgggcggc aagaacgggc
     8041 tggaagccat tgaaaagacc gtgatagacc gggctgtgcg cgtgatctac cggccctatc
     8101 tggcagaccc ccgcccggag aatatgccga tcctgtccga cctccacaaa gcgttgttag
     8161 atcagcatgt cccggaggct gaccgggtgg cgcaggccct tgacctgtat gtgtccggct
     8221 ccctgaacgt atttaaccac cgtaccaacg tggacatcgg caaccggctt gtgtcctttg
     8281 acattaagga gctgggcaag cagctcaaaa agctggggat gctcattgtc caagaccaga
     8341 tatgggggcg cgtcacggcc aaccgaagcc aaggaaaggc cacatggtat tttgccgacg
     8401 agttccattt gcttttgaaa gaggaacaga cggcggccta ttctgcggag atttggaagc
     8461 ggtttaggaa atggggcggc attccaacag gtgccaccca gaacgtcaaa gacctgcttt
     8521 cctccccgga aattgaaaat atccttgaaa acagcgactt cattacgctg ctcaatcagg
     8581 cgtccgggga tagaaaaatc cttgcggaac gcttgaattt gtccaccgaa cagcagaagt
     8641 acatcgacaa ttccgaaccc ggcgagggcc ttttgatctt tgaaaacgtg gtgctgccct
     8701 ttaccaaccc catcccgcac aacacccagc tttacaagat tatgacgacc cgcttaaacg
     8761 aggtggcggg agtatgaccc ggcgacgcca caaaggaggt gaaccaccat gaaagagctg
     8821 aaagccaagg cgaaagtgac gcaggccatg acccgcgacg ggctgacgct ggaaaatcag
     8881 gccaccggcg aggtggagaa catttccagc cgggaggccg aacaggattt gtccgcgccg
     8941 gggccgggcg gcaccgccga taagctgctg gaacgggccg acgccatcca tgacggccat
     9001 aaggccaaga aagccgcgaa gcaggccggg gctgtggccg ccgaggggga cgctgccctg
     9061 caccggccat ccgcccggct ccaactgtcg gaggaagaac gggccgaccc ggatttacag
     9121 ccctatatcc gaaaatcgga caaacgggcc gataagctgg ataaggcccg cgccgccatc
     9181 cccaagaagc gcgtcccggt caaggaaacc gtctttgacg aggcaagcgg caaagcaaag
     9241 accgtcctgc actttgacaa acaggacaag gggcctccct ccctgaaacc caatccggca
     9301 ggccgtcctg tttccgaggt ttttctattc ggccacggga aaatccatga agtcgagcat
     9361 gaaaacgtgg gtgtggaggg cggccataag ggggaggaac ttgccgagcg gcaggccgga
     9421 aaagccatcc gcagcaccat ccggcaccac aggctgaaac cctactggga cgcggaaaag
     9481 gccgagcgca ggctattgtc tgccaacgcg gagtatttct accagaaatc tttgcgggat
     9541 aacccggaga tcgcacaggc ggccagcaac cccatttccc ggttctggca gaaacagcag
     9601 atcaagcgcc agtacgccaa ggccgcccgg acagcgggcc agaccgcagg cgcggcggca
     9661 cagggcgcgg ccaagacagc cggggcctcc acgaaagcgg ccaaggccgc agccaaagaa
     9721 agtgaacggg cggcctcctt tgtggcccgc cactggaaag gggcgctggc cgtccttgtg
     9781 ttggggcttt tgatgctgct tatcatcggc ggcttacagt cctgcaccgc catgttcggc
     9841 agcgccggaa gcggcatcac ggcgtcctct tacttttccg aggatagcga tatgttggcc
     9901 gccgaggacg cctacgcgga gctggaagcc gagctgcaag actatctgga caactacgag
     9961 gccacccatg actatgacga ataccatttt gaccttgacg agatcagcca tgacccctat
    10021 gtgctgattt ccattctgtc ggcgctccat gacgggatat ttaccatcgg ggaggtacag
    10081 ggtgatttgt ccatgctctt tgacaagcaa tatatcctga cagaaaacgt cgtggtagaa
    10141 acccgttacc gcaccgaaac cgatacatgg acggacgcgg agggcaacac ccatacagac
    10201 acctaccaag tgccgtatga ctattacatc tgctacgtca cgctggaaaa cttcgacctg
    10261 tcccatgtgc cagtctatat catggacgag gaaacgctaa gtttctattc cctgtatatg
    10321 tccacgctag gaaaccggcc tgatctgttt tccggcagcc agtaccccaa cgcctccacc
    10381 ctgacgccgc cgacctacta cgacgtaccc ccggaggctt tggaggatgc cacctttgcc
    10441 gccatgctca aagaggcgga aaaatatatc ggttatccct atgtgtgggg cggcagctct
    10501 cccagcacca gctttgattg cagcggcttc atttcgtggg taatcaatca tagtggatgg
    10561 aacgtgggac ggctgggggc gcagggccta tataacatct gcacccctgt ttccagttcg
    10621 caggccaagc ccggcgacct tgtatttttc aagggaacct acgacacccc cggcgtgtcc
    10681 cacgtcggcc tgtatgtggg caacaatgtg atgctgcatt gcgggaaccc gatttcctac
    10741 acgaacctta cttcaaacta ctggcaatcc catttttaca gttacgggcg tttaccttaa
    10801 cgccagaaag gagctttcaa ttatggcaac caaacttgac cgcatcgaaa aggacatcca
    10861 gaaaaccaag tctaagatcg cggagtttca gaaacagctt cgggagctgg aaacgcagaa
    10921 aaccgaacag gagaatttgc agatcatcca gcttgtgcgc ggcatgaaca tgaagccgga
    10981 ggaatttgcc gcgttcttac gcagcggcgc aatgcaggcc gcccctgccg caacccctta
    11041 ccatgaacag gaggacaatg cccatgaaga ataagaccag acggatttcc cgtattctcc
    11101 ccgcacttct ggccgtgatg ctctgcgtca cggcctttcc cgttaccgcc cttgcaggcg
    11161 gcaatgaccc ggcaccggcc ccgctgccgg aggctacaac cgaacccgct acgggcggtt
    11221 tggagcctga aacagacgaa accggcaccg ccacggacgg gacagaaacc gaggccgaaa
    11281 aagataccgg ccctctgacc ggcaaggaca tcaccgacct gttttccgcg ctgttcggtt
    11341 ccaaggtgag cattgccgcc acggacgacg gcatccagat caccaccggc accgacaaaa
    11401 aagaacctga acagaccggc accgtcacca ccaacggcgg caggctgaat gtccgcaccg
    11461 gcgcggggct tgacaagacc gcgttcaccc agcttcccaa tgggacgacg gttgaggtag
    11521 tcggcacaga cggcgactgg attaaaattc tcttgccgga gcgcatcggc tatgtccatt
    11581 ccgactatat gaccgtcagc gaaaaggaag tagcggctac cggcgagggc ggtttttccc
    11641 tctccattga cccggaggaa attgcttctc tgctggaact gttcaatggc ggcggggcca
    11701 gcgccgccct gtccccggac gggaacctgt cactgattga cgacatcggc agcgccgcga
    11761 aaaatggcaa gcagtttatc accgtggaaa ccaaaaacgg caatgtgttt tatctgatta
    11821 ttgaccggga cgacgaggga aaagaaactg tccatttctt aaatcaggtg gatgaagccg
    11881 atctgctgac gctgatggag gacggggaaa ccgtcacccc cgctgctgtc tgctcctgta
    11941 ccacgaaatg caaggccggg gctgtgaaca cgaattgccc ggtatgtaaa accaacctga
    12001 ccgagtgcag cggcccggag ccgcaggaac cccagccgga ggaacccgaa gccccggagg
    12061 aagaacccaa gggcggcgcg ggcggcctga tcgtgttcct gctggtggcg ctggcgggcg
    12121 gcggtgcggc cctttactat ttcaagttca aaaagcccaa ggctgaaacc accggcagcg
    12181 acgatttggg cgagtatgat tttggggagg acgaggattt ggaggacgag gaacccgaaa
    12241 ccgagtttga cccggaagct gattttgtga gtgaacagga ggacgaggaa tgacatataa
    12301 acttgtaatc gcggaaaaac ccagcgtggc ccgcagcatt gcgggcgtga tcggggccac
    12361 ggagaaacac gacggctatt tggaggggaa cggctatctg gtgagctggt gcatcggaca
    12421 tctggtgtcc tttgccgacg ccggacgcta tgacgagcgt ttcaaaaaat ggcgctatga
    12481 ggatttgccc attctcccgg aaacatggca gtacatcgtc cccgacgaca agaaacagca
    12541 gtttgacgtt ctctgttcgc tgatgcagcg ccccgacgtg accggccttg tgtgcgccac
    12601 cgacgccggg cgcgaggggg aattgatttt ccgtttcgtc taccagatgg cgggatgcca
    12661 aaagcccttt gagcgccttt ggatttcctc tatggaggac agtgctatta aggacggctt
    12721 tgcccacctg aaaccgggcg gcgactatga tccgctgtat caatcggccc tgtgccgggc
    12781 caaggccgac tggctgatcg gcattaacgc cacccggctt ttttccgtcc tgtaccacaa
    12841 gaacctgact gtgggccgcg tccagacgcc gaccttaaaa atgctggtgg acagggacgc
    12901 caagattacc gatttcaaga aagagaaata tcacatcgtc catatcacgg cgggcggcgc
    12961 ggacgcggta agcagccgct tttccgacgc tgccgaggca aacaccgtca aggcggcttg
    13021 tgcaaaagcg caggccgttt gcgtttccgt gacgcgggag aaaaagacgg aacagccgcc
    13081 caagctctat gaccttacca ccttgcagcg ggaggctaac cggcttttcg gctataccgc
    13141 caagcagacc cttgactatg cccaggcact gtatctaaag aagctgctga cctatccgag
    13201 aacggatagt caatatctta ccgacgatat gctgcccgcc gtggaaagcc ttgtgtccgg
    13261 cctgtgggag ctggtgccgt ttgccaaggg cctgaacctt tccccgcagt ttgaccgcat
    13321 cctgaacagc aaaaaggtgt ccgaccacca cgccattatc cccaccgctg aatttgtgaa
    13381 gcagggcttt ggcactctgg ccgagagtga aaaaaagctg ctgtccctga tctgctgcaa
    13441 gctcttatgt gccgtggccg ggccgcatat ctatgaggcc gtcaccgcca catttacctg
    13501 tgccgggcag gagtttaccg ccaagggcaa gaccgtcctt tcccccggct ggaaagagat
    13561 tgaacgccgg ttccgttctt ccttaaagac cgacgccgac gaggacgccg aggcggtgcg
    13621 ggagctgccg gagctttgcg agggccagac ctttgcagac gtggccgcct ctgtcaccga
    13681 gcatttcacc acgccgccca agccctacac cgaagatacg cttttgtccg ctatggaacg
    13741 ggccggggcc gaggatatgc cggaggatgc cgagcgcaag ggattaggca caccggccac
    13801 ccgcgccgcc attctggaaa agctggtgca gatgggcttt gtccagagaa aaggcaagca
    13861 gctcattccc accaaggacg gcatcaatct ggctgtggtg ctgccggagg cgcttacttc
    13921 tccccagctt actgccgaat gggaaaaccg gctgaccgag atcgccaagg ggcaggccga
    13981 tcctgacgaa tttatggacg gcatcgagac gcaggcgcgg gagctggtgc agacctattc
    14041 ctgtatcagt gaggaaaagc agaaattgtt tcaggccgag cgtgttccta tcgggacgtg
    14101 tccccgctgt ggtgaggctg tctatgaggg caagaaaaac tactactgcg gaaaccgggc
    14161 ctgccagttc gtcatgtgga agaatgaccg attttttgag gaacgcaaga aagcgttcac
    14221 cccgaagatc gccgctgcgc tgctcaaaac cggcaaagtc aaggtaaagg gcctctattc
    14281 cgtaaagacc ggcaaaacct acgacgggac ggtgcttttg gctgataccg ggggcaagta
    14341 cgtcaactac cgcattgaac acaggagcta aaggacagta acacagcaag catagggagt
    14401 gtggctacac tcccggtaaa atcccccggc cgcgtccctg ccgggccggg gatttttgct
    14461 tgttggggaa gtccccaacc ccctattttt tgaaacagaa cagagaaagg agtgaccgcg
    14521 tgaacgaagt attttctatc caagtccata accggcagtt tttggaacag ggcaaacaag
    14581 gcgtctggct ggatttgccc accacaaccg aaacgctgca agccgccctg cgggatgttg
    14641 gcattactgc cgacaatccg caggattttt ttatcaacgg gtattcctgc ccggaggaca
    14701 gacaccttgc cattccctat gacatggtgc tggccgccga cgtggacgag ctgaatttcc
    14761 ttgccgcccg gctgggccag cttgacgccg ccgagatcgc agagctgaac gccgccctgc
    14821 aaaatccccg tggcggcttt gagaatatcg gccagatcat cgactacacc gaaaatgtgg
    14881 attactatgt gcatcttccc gacgttaggg gggatggaca gttgggcgac tactacctga
    14941 accgttccgg catggtggat atgccggagg aatggaaagc cgggattgat acggcgcagt
    15001 ttggacgcca cattgcccag caggaacaag gcgtttttac ccagtacggc tatctggtga
    15061 gaagcggcga cgaatggcag cgcgtccatg agggccagcc ggtgccggag gaataccggg
    15121 tgatgcacta cccccagccg gaagctgacc gggaggaacc gcaggcccag cagccggagg
    15181 catccgaaag ccccgacaaa gcgccgcccc cggttatccc gatcatgctg gacggcatga
    15241 acagcaaaga acgcatgaaa gtgattactg accgtctgga aaccggcgta caggagcttt
    15301 ttgaaagtag ccgctatatg gcttacttat ccgctatgtc caagatgcac gattacagtc
    15361 tgaacaatac gctgctgatc gccatgcagg gcggttcgat tgtggcgggc tataacaggt
    15421 ggcaggatga atttgaccgc catgtgaagc ggggcgagaa aggcattaag atactggccc
    15481 cggccccgtt caaggttaag cagcagatgg agaaaatcga cccggccacc cagcagcccg
    15541 tgatcggcgc ggacggcaag cccgtgaccg aagaacagga agtgacggtt ccggccttta
    15601 aggtggtgac agtctttgac atcagccaga ccgagggcaa ggattttccc atgccctata
    15661 tcagtgaact taccggcgac gtgcagcagt atcaggattt ctttgccgcg ctggaacgga
    15721 catcacccta tcccataagc attgagccga tttcagacgg ggccaagggc cgctgcttct
    15781 acgcaaaaca gcgcattgcc atcaacgagg gcatgagcga attgcagacc ctaaagaccg
    15841 ccatccatga gattgcccat gccaagctcc acgccattga ccgggaggcc cccgccgagg
    15901 aacaggcggc ccggccagac cgcagcaccc gcgaggtaca ggccgaaagc gtggcctata
    15961 ccgtctgcca gtattacggg ctggacacgt cggactattc ttttggctat gtggccgatt
    16021 ggagcagcgg cagggagtta tccgagctga aagcctccct tgaaaccatc cgggccacgg
    16081 ccagcgaatt gataaccgag atcgacggcc attttgccca gcttcagcag gagcgcgagg
    16141 cccggcagga acaggaggcc gtcacggttg acgttacccc ggaggcagcg gccccggcgc
    16201 aggccgagga agaacaggcc ccggcccttg atccggcagc cgagccgctt gtgactgtgc
    16261 tatggagcga aagcccccag ctaaaggacg gccagcaaat gccgttgcat gaggccgacg
    16321 cgctgtttgc ccgtctggat gcagcatatc cggcagaggc aggctatgac aaaaccgcgt
    16381 tccgcattga ctgtatcttt cagggcgagc cggacagcta cgaggggcgg caggattttg
    16441 gagataggga cggttccctg atcgaacata tccagagcta ccaccaattt tacgcgcagg
    16501 acgaaaactg gaaaaagcat gtaatcgcta caaccggcat agagggctgg gagcaggaca
    16561 aggcccatcg ggatatgctg ttaggcgagt ttgtccccta tatgaagctg cattgcagcc
    16621 ttgcccaaat ggaacagacg gcgcagggcc gcttacagtc cggggaaacc ctgacgccgg
    16681 aggaaacggc ctatttgggg gcgcttctct cttatgtgca ggagtgccgc cccatgctca
    16741 atcagggcca gtatcagttg ccggagccgc cgaaactggc tgacttcgac cagagcttgc
    16801 aggactacaa agcacaggta caggccgaga tcgcgcagga ggccgccgca gccggtatga
    16861 ccgtggagga atacgcggcg gctggctatg aagcacccca acaggacacc ttttccatct
    16921 accagcttcg aggcggggag gaaacccgcg actatcggtt tgagccatac gagcgtttac
    16981 aggccgcagg gctggccgtg gacagtgcca actatgacct tgtttatacg gcaccgctgg
    17041 ataaaagcac gtctttggag gatatttacc gcacattcaa catcgaccac ccggcagatt
    17101 ttaggggaca cagcctttcc gtttccgacg tggtggtgct gcaccagaat ggacaggaca
    17161 ccgcccacta tgtagacagc ttcggctata tggaagtgcc ggagtttttg cgggaaaatc
    17221 ccctgcgtac cgccgaactg tctacggagc agaacgaaaa catgattgac ggcattatca
    17281 acaatacgcc gcccgaaccg cagccggagg aacccgaaca gctatctttt gaggatgtgg
    17341 cagttgcttc cggccagaca caggaggaac ccccggaggc tgcgcccccg caaacggctg
    17401 tccgctatta tcccatcaat gagggagccg cccgccgcgc caaggaagcc atgagctttt
    17461 ctgactaccg gcccggcagc gccacggcgg aataccggca ctatgtcgat caggccgtgg
    17521 aaattgcgga gcgccagaaa aagcgtgtgg agccagagta tcacgaaaag atagacagcc
    17581 tccttgacac ctacgcccgc aagctggccg agaacatgaa taagggctat gagattaccg
    17641 cccgcgtccc ctctgtcctg attgccgggc cgtccaattt cccggtacgg gcgaaagaaa
    17701 agcagaacgc cgccagtgac cgcaacatgg aggaatttca gtacattcag ggcttgcttg
    17761 acaaaatccg cagcaccggc atgggtggta tcagcgccga cgatccgcag gccgtttcca
    17821 agctggaaaa gaaactggaa aagctggaag cgtcgcagga gttgatgaag gccgtcaatg
    17881 cctactaccg caagcatggg acgctggacg gatgccccca tctgaccgaa agaggcattg
    17941 aaaacctgaa agcggatatg gcgtcgggct ggcactatga gaaaaaaccg ttccagtcct
    18001 ggcagctccc caacaataac gccgagatac gccggttaaa gggccgcatt gaggaattga
    18061 cccgccaaaa ggaggcggcc tatgtgggat gggagtttga cggcggcact gtggagatca
    18121 accgggtggc caaccgcctg caaatcttct ttgaggggaa gccggatgct gctgtacgcg
    18181 acgagctgaa aagcaacggt ttccgctggt cgcccaaggc cggggcatgg cagcggcagt
    18241 taaacgacac cacaatccgc gtcgctgacc gtatcaagtg catccagccc ctttccggcg
    18301 aaaagcccag cgccttacag cttgcggccc gcagggagaa agaaaagccc tctatccggg
    18361 cgcagctcaa cgcggccaag accgaacagg ccaagcagcc accggcgcgg gaaaaatcaa
    18421 agggattgga ggtagagtaa atgcagaagt ttgaaaatgt ggacgttctg gccgcgctgg
    18481 aacagatcat gcggcagaac accgcgtttt atcaaagtga ctttggcatt gacaaagaca
    18541 ttatcaggcg ggatgccgcc agcgatcagg ccgcagacaa gaccctgctc tggatgtccc
    18601 ggccctccgg gacgtactgt ttccgggaac gtgatgtttt cctgaaagac acccgacagt
    18661 acaacacatg gaaattttac ggggagcaga cccgtgacaa gatactggcc tacgcggtgg
    18721 agctgaccgg cacacagggc ggcactatcc ggggcaatct ctatgagctg gactatccgc
    18781 agcatttccg gcacgtcatt gaaaccgccc agccggtgag tgtgaaccgg ctcttttatg
    18841 agcatggcac ccgtgacatc ccggagagcc agcgttttga cggaagccct gaccgggtat
    18901 tgggaaactt tttgtactat gaggcccagc cccatgaccc ggctgtgctg caggaggcgc
    18961 tacggacgga gcagcacagc cgggggcggg ccgtccccgg cgatttcaaa gtccacgtca
    19021 ccgctttgca tgacagccgg attgaaaccg aggcccggcg tattgtggac agcctgaaag
    19081 atctgtccgc gcctaacagc cccaataaaa cgcatttcat ggtggagatc tccccgcact
    19141 ttgcggcgat tgcttccacc aaggataatg accggctctt tgccatgctg ccctataaat
    19201 ccctgtgttt taccgggatg aaaggcaggc atggcgtgta tgccgtgatt aaccgggacg
    19261 agcgccggga tgtgagtatt cgcaggcccc ggccctctat ccgcaagcag ctatccgaca
    19321 gcaaacaggc cgccagccca aaaaaggcgg cggccagaac caaaaagaat gaattggagg
    19381 tataaggaat gatgcacttt accgtggagg aagaaaacct gatctgtatg taccacaatg
    19441 cagaccggcg cagaacgata aacaggctca ccgccgtcat gccggttatg gatggggata
    19501 tgcgggcgca ggcccagcag accctttcca agctggaacg catgacggat gccgactatg
    19561 acggccagaa gttccacttc acagacgaat aacgaacagc agacgccggg cgcggcggcc
    19621 atgtggtcgc ttgcgtccgg cgtcttttct ttttgcctat tcctacgcat ttagaacccg
    19681 gtattgtcgg ggataggatg aagtattcgc ttgcccctgc aaacatgcgg gagaagcctt
    19741 gcagcgggcg gttttcaatc ccttaaatgc gtaggttgca gctataatta gacccctgaa
    19801 acagatatag ccgcgcagcg ggtgtatctg tttcaggggt gtgcaggtga tagccgcaaa
    19861 gcggcgtaag agggtgcagc cctcttgccg tctatctctg ttccagcggg aagctcggca
    19921 atgcttccag cagtttcagg gaaatgcgct gccgtatatc ttcgtcaatg actttcttct
    19981 ttttgccgtt tgcctgtctg atctccaccg tggaaagctc gttgatgtag tcagcataat
    20041 gggccaacac tttttccgtg gcccacctct caccggcaac ggcggctttg atcgtttcat
    20101 agtccagcag cttttcttgt ccgtccatcc tgataccccc gtcagactga ttttttctat
    20161 gataccatat tcggaagcat ggaaccagag aaaacggcgc ttttctgctg gtaaattcta
    20221 cgcatttaga acagcacttc ggcggggata ggataaaaca cccacatacc ccgctgacca
    20281 tgccggaaaa gccttgaaat ataagggctt ttacagctct aagtgcgtag gtttccagta
    20341 tcttttccgc tggcgctcgg cctctttgcg gcggcgcatc cgtttggagc aggccgcgca
    20401 gtatttggcc cggttagact tcggcgtgaa cgtggccccg cactcacagc agcgtttcac
    20461 ttcgtcccgg tctttggtga tctcggcata cagggccgca tccagcggga ggacagcggc
    20521 cttaaaccag cggcacagaa gcgaatagga aatgctctgt acgcaaatac attcttcgcc
    20581 gtcgtccagc aacaggcagt tgccgtcaca atagttgcag cactcatgcg tcagcttccg
    20641 ggccttgcga tattgagggt aattcattcg tggaatactc atagctcttg cgtccattcc
    20701 tttcccggcg tcatacgcaa aatgccgtcc acattctgct tgatgatgcc gtattcctgc
    20761 atctgctttt tcgcttcgcc gtacttctca tacagccgtt ccttttcctc ggccaatcgc
    20821 ttgtactcgg ctttcagggc gtacagatcg gggagctttt tcacaccctg tccctttagg
    20881 gcctttgccg cagcttcata caaaatcaac gtgctttcat gctcacgccg gaattttgcc
    20941 ttatccgctg cattgcggta ttccatagcc acgggccaga gctgcttgta ggtagaaata
    21001 ttctttatca gcaccgccat atccgcaagc cggtgttcca tagctttgag ggtagcggcg
    21061 gcctcgtcgc tggcggcggt gatctcggcc actttgcttt ccaaatccgg gtaggtgtct
    21121 atcccatgtt cagtcaggaa attcaaagtc tttgcggcct gcttcaaatt gtggagcttc
    21181 gcccacctct catagcctgc cgactgctgg gccttaatgt tgttttccag atcaatccgc
    21241 aaagaaatcc ccttgcgctc tttgggcgct ctggtgataa cgcggccttt gatacgctct
    21301 ttgatggctt cctcggtgta ggcttccccc aatgtcttgc agcgggtaaa gcgttcctgt
    21361 ccgggagcgc ggaaagaaat aaactttccc ggcttgatct catagccctg cgcctgcatg
    21421 agccgcagga aatcatcaaa atcttttgcc tgcgggatag cggcgtcaat ggctgctttg
    21481 agcttcgctt tccagctcgt ccctttccgc tgggcgtccc actcggcata gctcttgccc
    21541 ttactctggc cgggcttcac cacggacaat ccgttttcct tgcacagcct gtcgctggtg
    21601 cgccggatat aggcatagct ctgtttgttg gaaatgtact tgcgctgatt taccatatcc
    21661 acggcacaga aaataatgtg attgtggacg tggcccttat caatatgggt agtcagcaca
    21721 tagggatatt tcccttgcag cacttcctcg gcaagctgct tcccgatctc atgggcctgt
    21781 tccggcgtgg cttcgccggg ggcaaaggat tgtatcaggt ggtggcccag attattgccc
    21841 ttttggtatg cctgcgccag cagcatttca aattcaatgt ccgctgtttc ataagagcag
    21901 gcaaaggagg ccaccagcag cttgccgtca gttttgtccg ggttctcgat gtagtcaagg
    21961 gcttttttca gcgttgactt gataggatgt atctttgtaa ctgccatatc tgcgccagcg
    22021 ccccctttat atcctcgatg tcctgtgcgt acaccggccc cataccgttc agcctctttg
    22081 caatctgatt gacgttgacg ccgatcttct gtatctcggc ggtctgcgcc cggatgtcgc
    22141 tggtgtccat gttgacgata tagccgtcaa tgagcatctt ccgggcgtag gctgaaaagt
    22201 tcttcgtatg cagcagcgcc attttctgtt caatcatagc ccgttcctcc ggcgtcacag
    22261 ggacgcgcag cacgattttt cgctttctgt ttgccatgct tcaccgtcct ttccattcag
    22321 gggtttgggg atttccccaa caagcaaaac ggacgcggcc cggcagggac ggggcaggcc
    22381 gtttttccgg gagtggctac actccctatg cttgctacgt tactgtttct ccactaacaa
    22441 gacgtttcca aagccccaaa ctacccgcaa aatagccctc tggaaagaaa aaagtgcaaa
    22501 aaaatagaag ctacgctgtg cagctcccgc taaaagtaaa acagaggatg ccagttacac
    22561 atcctccgtt tcattcttct tcggcttttc aattagtatg gcgctgtcaa tcgcgccctc
    22621 gatgatcggc aggtattctt cggggcagag tttcagcttg tggctgaccc tttgccgcag
    22681 ttcgctttcc tcccgcatga tctccgggtt aaagtagcgt tccacaggaa gcccgcaggc
    22741 tttaataagc tgtatgacaa ccggcagact gggaatggcc ccgtcgtttt cgatgttggc
    22801 aagatagcgc cagtcaatat ttattttctc tgccattgct ttgcgcgaaa cgcgctttgc
    22861 ttgccgggcc gctttcacat ccgcgccgaa agtttcaaag ccgggacaat cttcaatatt
    22921 cgccatatcg cacctcccac ttacattgta tatttcatac tctgcccgtg gaatgttggt
    22981 atatgcacct ttcttaaagt ttatatttca cattttgttt cttttattct tcgagcaaaa
    23041 gaattataat gtaccctgtg gaggtgtact atggactaca tgacgttgaa agaggcaggc
    23101 gagaaatggg gtgtgccccc acgatggata aactactatt gtgctgcggg acgcatcccc
    23161 ggcgctgtaa agatggcgac gatctggctc attcccaaaa ctgcggaaaa gccgattgac
    23221 aggcgtacaa agaaaggaaa ggcggttact gaatagtata atgaaaccgg cgcattttgg
    23281 atatggtttt gaagagagag aaagcatggt attttgtcac ggaaaaacta taagatgata
    23341 gatggcaggc tgctccagac cgataaaaag tattctcatc tgaaacagaa agaaaagatt
    23401 tacacatgga tgtatgaaga agcgaaactt tatcatgaca gaaatggaaa atgcccgaaa
    23461 caaagacgag gaagctgctg ctgtatcagc cgtatatggt agaattgaaa aggccggcat
    23521 ctggattctt tatggtgaag tctccagaca ttggataact gctggtctaa tgcgcctttg
    23581 agtatggggt gattgatttt aataccgggg aggtacggct ttttgaggaa aatattctgg
    23641 gatttacatt tggcgattat tacatttcct gtaactgcaa ggacacggat gatgaagata
    23701 tgaggaatat agacttgctg attttctact gtcttgaacg gtattaggac tgaatctgct
    23761 gcgcggagtg cggcaagagc gaccggaggg agtacacaca ggccctgcct gtgtgaaaag
    23821 ccataccgca aggtgcattc gcaaaaaaga ggccgcgcat tttgctgagg cttggggtgt
    23881 ccccaacaag caaaacgaga acgccgcagg cgggcaagtg gtggatcaga atatccgtaa
    23941 aggatattct gatccattgc ttgccagtat tatcgggatg ttttgacaac cgctgtaatc
    24001 gaaacatccc aaacattaag aaggtgttaa ttattattat cttgatttaa ttcgtttaaa
    24061 ccaataatat agatacatac accatgaaaa gaagcgagta tcccaatgac ggatgattaa
    24121 aatccgaaaa gaaatcgctt tgaaactaca gggaaactac agactgttat gttatcttct
    24181 taaaatggag ggatttttat gtcgatacga attctacttg tcgaggatga tgatcatatc
    24241 tgtaatacag taagggcgtt tctggctgag gcaggatatc aggtggatgc ctgcacagat
    24301 ggaaatgagg catacaccaa gttttacgaa aacacttatc aactggttat tcttgatatt
    24361 atgctgcccg gtatgaacgg gcatgaactt ttgcgtgaat ttcgtgcgaa aaatgatact
    24421 cccattctga tgatgacagc cctgtcggat gacgaaaacc aaatccgggc gtttgatgca
    24481 gaggcagacg actatgtaac aaagccattc aagatgcaga ttttactaaa gcgggtggaa
    24541 gccctgctgc ggcgcagcgg tgcgctggca aaggaaatcc gtgtcggcag gctgacactt
    24601 ctgccggagg atttcacggt actttgtgac ggtacagagc tgcccctgac acgaaaagaa
    24661 tttgaaatcc ttttgctgct ggtgcagaac aaaggcagaa ccttaacgca tgaaatcatt
    24721 ttgtcacgta tatggggata tgactttgag ggtgatggca gcacagtcca cactcccaca
    24781 ctcatatcaa aaatttgcgg gccaagctgc cggaaaatat catcaaaacc attcgcggtg
    24841 taggataccg attggaggaa tcataataat ggaaagaaaa gggattttca ttaaggtttt
    24901 ttcctatacg atcattgtcc tgctactgct tgtcggtgta acagcaacac tgtttgcaca
    24961 gcaatttgtg tcttatttca gagtgatgga attacagcaa acagtaaaat cctatcagcc
    25021 attggtggaa ctgattcaga atagcgatag gcttgatatt caagaggtgg cagggctgtt
    25081 tcactacaat aaccaatcct ttgagtttta tattgaagat aaagagggaa gcgtactcta
    25141 tgccacacca aatgccaata catcaaatag ttttagaccc gactttcttt atgtggtaca
    25201 tagagatgat aatatttcga ttgttgctca aagcaaggca ggtgtgggat tgctttatca
    25261 agggctgaca attcggggaa ttgttatgat tgcgataatg gttgtattca gccttttatg
    25321 cgcgtatatc tttgcgcggc aaatgacaac gccgatcaaa gccttagcgg acagtgcgaa
    25381 taaaatggca aacctgaaag atgtaccgcc gccgctggag cgaaaggatg agcttggcgc
    25441 actggctcat gatatgcatt ccatgtatgt caggctgaaa gaaaccatcg caaggctgga
    25501 ggatgaaatc gcaagggaac atgagttgga ggaaacacag cgatatttct ttgcggcagc
    25561 ttctcatgag ctaaaaacgc ccatcgcggc tacaagcgtt ctgttggagg gaatgcttga
    25621 aaatatcggt gactacaaag atcattctaa gtatctgcgc gaatgcatca aaatgatgga
    25681 taggcagggc aaaatcattt ccgaaatact ggagcttgtc agcctgaatg atgggagaat
    25741 cgtacccata gctgaaccgt tggacatagg gcgcacggtt gccgagttgc tgcccgattt
    25801 tcaaaccttg gcagaggcaa acaaccagcg gttcgtcaca gatattccag ccgggcaaat
    25861 tgtcctgtcc gatccgaggc tgctccaaaa ggcactatcc aatgtcatat tgaatgcagt
    25921 tcagaacacg ccgcagggag gcgaggtacg gatatggagt gagcctggtg ctgaaaaatg
    25981 ccgccttttt gttttgaaca tgggcgttca cattgatgat actgcgcttc caaggctgtt
    26041 caccccattc tatcgcattg atcaggcgcg aagcagaaaa agtgggcgaa gcggtttagg
    26101 acttgccatc gtacaaaaaa cgctggatgc catgagcctc cagtatgcgc tggaaaacac
    26161 ctcggatggc gttttgttct ggctggattt accgctcaca tcaacattgt aaatatttaa
    26221 aacttaaatg attttgaccg acaggtataa ccctgccggt ctttttttgc tgctacagga
    26281 aaactacaga ctggctacag ggaaagtaca gatgcgcttg ccataataac aatcgtacca
    26341 gccacaaatc gtagttttat tgcaaaggag gcattcgatc aaatggaaaa aagcaactat
    26401 cattccaatg cggatcatca caaacggcat atgaaacaat ccgtggaaaa gcgggctttt
    26461 ctatgtgcgt tcattatttc gttcacagtc tgcacgctgt ttttggggtg gagactggct
    26521 tccgtattgg aggcaacaca gataccgccc atccctgcaa ctcatacagg cagcagcact
    26581 gacgtagtgg agaatttgga ggaaaacgct cttgccaccg ccaaagaaca gggagatgaa
    26641 caggaatgga gcctgatttt agtgaacagg cagaacccca tccccgcaca gtacgatgtg
    26701 gagcttgagc aactatcaaa tggtgagcgg atagatattc ggatttctcc ctatcttcaa
    26761 gatttgtttg atgccgcaag aactgatgga gtttacccga ttgtcgcatc cggataccga
    26821 acaacagaaa aacagcaaga aattatggat gaaaaaattg ccgaatataa ggcgaaaggc
    26881 tacacctctg cacaggctaa agcggaagca gaaacttggg tggccgtgcc gggaacgagc
    26941 gagcatcagc ttggtcttgc tgtggatatc aatgcggacg gaattcattc aacaggcaac
    27001 gaggtttata gatggctgga tgaaaacagc tatcgttttg gttttattcg tcgctaccca
    27061 ccagacaaga cagagataac cggtgtgagc aacgagccgt ggcattaccg atatgttggc
    27121 atcgaagctg ccacagagat gtacaaccaa ggggtttgcc ttgaggaata tttaaaacca
    27181 gaaaaatgag aaaaggatgt tatgttatgg acagaaaaag attgacacag cgtttcccgt
    27241 tcctgcttcc aatgagacgg gcgcagagaa aaatgtgctt ttatgcggga atgagatttg
    27301 acggctgtcg ctatgcgcag acgatagggg aaaaatcgct ttcccatttg ctctttgaaa
    27361 cggattgcgc attatacaac cacaataccg gatttgacat gatataccag gaaaacaagg
    27421 tgttcaactt aaagctggca gcaaagacct taaacggctt attgataaga ccgggggaaa
    27481 ccttttcttt ctggtggctg gtacgccatg cggacaaaga taccccctat aaagacggcc
    27541 ttacggtgac caatggtaaa ctcaccacca tgtcgggcgg cggtatgtgc cagatgagca
    27601 atttactatt ttggatgttc ctgcatacgc cattgacaat tatccagcgc agaggtcacg
    27661 aagtaaagga gtttccagag ccaaacagtg acgagattaa aggggtggat gcaaccattt
    27721 cagagggctg gattgattta aaagtgcgaa acgataccga ctgcacctac caaatatggg
    27781 tgaccttaga tgatgagaaa atcatcggtc aggtgtccgc cgacaaagag ccccaagcat
    27841 tatacaaaat tacaaatggc agtatccagt atgtccgtga aagtggcggg atttatgaat
    27901 atgcccaggt taaacggatg caagttgcct taggtaccgg ggaaataata gattgcaagc
    27961 tgctttatac aaacaaatgc aaaatctgtt atcccctccc ggaaagtgtg gatattcagg
    28021 aggagaacca atgagaaaaa gtgtgggcat tactgttttt ggatgcgaac aggatgaggc
    28081 aaatgctttc cgcgctttat cgccggattt tcatattatc cctacgctga ttagcgatgc
    28141 gatatcggca gacaacgcaa aattggccgc tggcaatcaa tgcgttagcg taggccataa
    28201 gtccgaggtt tccgaggcga caattcttgc gctgagaaag gtcggggtaa aatacatttc
    28261 tacccgcagc atcggctgcg atcacattga tacgactgcc gccgagagaa tgggaatctc
    28321 ggttggcacg gttgcgtatt cgccggacag cgttgcggat tatgctttga tgctgatgct
    28381 gatggccata cggggtgcaa aacccaccat gcacgccgtg gcgcaacaag atttcagatt
    28441 ggatcgtatc cgggggaaag aactggggga tatgactgtg ggagttattg gaaccggcca
    28501 tatcgggcaa gcggtcgtca aaaggctgcg gggatttgga tgccatgtgc tggcctatga
    28561 taacagccga aaaatggatg cagattatgt ccagcttgat gagcttctaa aaaacagcga
    28621 tattgttacg ctccatgtgc cgctttgtgc ggatacccgc catctgatcg gtcagaagca
    28681 aattggagag atgaagcaag gcgcattttt aatcaacacc gggcgcggag cgcttgtcga
    28741 taccggggcg ctggtggagg cgttggaaag cggaaagctg ggtggtgcgg cactggatgt
    28801 gttggagggc gaggatcagt ttgtttatac cgattgctcg cagaaagtgc ttgaccatcc
    28861 ctttttgtcg cagcttttaa ggatgccgaa tgtgatcatc acaccccata cggcgtacta
    28921 cactgagcgt gtgctgcagg atactacaga aaaaacaatc aggaattgtc tcaattttga
    28981 aaggagttta cagcatgaat agaataaaag tcgcaatcat cttcggcggt tgctcggagg
    29041 aacatgatgt gtcggtaaaa tccgcaatag aaattgctgc gaacattgat acggaaaaat
    29101 tcgatccgca ctacatcgga attacaaaaa acggtgtatg gaagctatgc aagaagccat
    29161 gtacggaatg ggaagccgac agtctccccg ccatactctc cccggatagg aaaacgcatg
    29221 ggctgcttgt catgaaagaa agcgaatacg aaacacggcg tattgatgtg gctttcccgg
    29281 ttttgcatgg caaatgcggg gaggatggtg cgatacaggg gctgtttgta ttgtctggta
    29341 tcccctatgt gggctgtgat attcaaagct ccgcagcttg catggacaaa tcactggcct
    29401 acattcttac aaaaaatgcg ggcatcgccg ttcccgaatt tcaaatgatt gataaaggtg
    29461 acaagccgga ggcgggtgcg cttacctacc ctgtctttgt gaagccggca cggtcaggtt
    29521 cgtcctttgg cgtaaccaaa gtaaacggta cggaagaact taacgctgcg atagaagcgg
    29581 caggacaata tgatggaaaa atcttaattg agcaagcgat ttcgggctgt gaggtcgggt
    29641 gtgcggtcat ggggaacgag gatgatttga ttgtcggcga agtggatcaa atccggctga
    29701 gccacggtat cttccgcatc catcaggaaa acgagccgga aaaaggctca gaaaatgcga
    29761 tgattacagt tcccgcagac attccggtcg aggaacgaaa tcgggtgcag gaaacggcaa
    29821 agaaagtata tcgggtgctt ggatgcagag ggcttgcccg tgttgatctt tttttgcagg
    29881 aggatggcgg catcgttcta aatgaggtca ataccctgcc cggttttaca tcgtacagcc
    29941 gctacccacg tatgatggcc gccgcaggaa tcacgcttcc tgcactgatt gacagcctga
    30001 ttacattggc gttaaagagg tgataagtat ggaaaatggt tttttgtttt tagatgaaat
    30061 gttgcatggc gtccgttggg atgccaagta cgccacatgg gataacttca caggaaaacc
    30121 ggtggatggg tatgaggtga atcgcatcat cggcacaaag gccgtggcgt ttgctctgcg
    30181 cgaggcacaa atccatgcgg ctgcgcttgg ctatggcttg cttttatggg atggatatcg
    30241 gccaagaact gcggtggact gcttcctgcg ttgggcagcg caaccggagg acaatctcac
    30301 aaaagaaaaa ttttacccca atatagagcg agccgagttg attacaaagg gttatgtggc
    30361 ctcacaatcc agccatagcc gtggaagcgc aattgatctt acgctctacc acctggatac
    30421 aggggaactt gtttcaatgg gaagtaactt cgattttatg gacgaacggt cgcatcatac
    30481 agcaaaaggg ataggggatg cagaggcaca aaatcgaaga tgcttgcgta aaatcatgga
    30541 aagcagcgga tttcagtctt atcgctttga atggtggcac tataagttga ttgatgagcc
    30601 ataccccgat acctatttta attttgccgt ttcataatga aagtattggt tttgtatcag
    30661 attttggatt tgataaaatc tatgctggtc atggacaatc ttttactgga aagtggttaa
    30721 agcatctttt gtaatacatt gcaaattata gtattcaatc tgcccagcgg cagaaaagaa
    30781 aaaaaccgct gttgggcaga cctttcccac gcccattttg tattttgctg gcggcggttt
    30841 tgagaaatga accgccccct gtcaagtaga cagatgaaaa aagaaaaatt acgccacgag
    30901 ggtctggttc ctgtaagcaa ggggagccag gccctttaac ttagcttgaa gccgccttgt
    30961 attgtaaaag tctatgtatt cgtcgatggc tttcttcaat tcctcgaagg tatgaaattg
    31021 ccggaggtag tacatttcag atttgagaat cccccagaag ccctccatag ggccgttgtc
    31081 gatgcagcgg ccgggccggg acatactctg cgttgcatgg ataccgtcca gctttgcttt
    31141 gaactgccgg ttggtgtact gatagcccct gtcgctgtga aacagaggat gggcgccggg
    31201 gttggctctc accgctctgt caaaggtgtc aaaaacaagc tgattgttgt tggattggcc
    31261 cagtgcatac gcaacgatgc ttttgtcatg gagatcaagg atcgcactca ggtatgcttt
    31321 cttcccattg ataagtttga attctgtgac atctgtcagc catttctcat tgggaccatt
    31381 tgccgtaaat tctctgttca atacgttttc cgcggtaaca cgcggttcta atatgacata
    31441 gtgctttttc tttcggcgta tcacggcctg catatgtaca cttttcatca ggcggtaaat
    31501 ccgcttgtgg ttgtagtttc ttttgagccg gctgttcaca ttcagcgtca tacggcgata
    31561 accgtagatg ccttttactt cgctgtacaa acggatgatt tcttccagca agagggtatt
    31621 ttctttttct gaggcacttt cttcccggtg aagccatttg tagtaagaac agcggggaat
    31681 cccggataac gcgcataacg atgcgatttc atatcctttt tcctgacgaa gcgtatggat
    31741 cgcctcatag accttcctgc ggcgtgtgag cctgtttacc gcctcccctc cagttcgttc
    31801 aattttttta agaaatcgtt ctccatttga agccttctgt tttccgcttc cagctgccgc
    31861 agctttgccg cggctttttc ctcctcgctg tattcggaag gagggcggcg tctcccccgg
    31921 cggtcaagca acccagcttc tccctgctcc tgatattttt tgacccagct atagatctgc
    31981 tgataggtga tcttgtactg ttcgctggtc cgccggtagt ccagttgatg ttctaagcag
    32041 tatagtactg cctgcagctt ttgctcctgc gataattttt ctttctcggc catatctgtt
    32101 tcctcccgcg ctctgcgtgt cttgaactct ctatggcctt gattatacaa cgtaatccat
    32161 tgttgtaaaa ccgcatggga ggaaatcccg tatttgcggc acatggcatc cagcgagcct
    32221 cctccgccca tgtagtcttc tactgccgcc agcttcagtg aggatggata acttgtaaca
    32281 tgctttttcg gatgcagacc cgcaggcccc tccgtctgat atttccgcag ccatgcctgg
    32341 aaagtgctca atcgtatgcc taactcttcc cggatctgtg tggaaccctt acggatcgct
    32401 aggtagtcct ccacagcctg aatctttacc tccggcggta ttttgccttt taaactcatg
    32461 ataattgctc cctccgtttc gacagtttaa tttttttgct gtctacttca gagggagcat
    32521 atcaaaatca aggccgccgt tcttttctgg cagcaaaagg tgtggcggcc cataggagga
    32581 tgccgctatg ctgttttgct attgccatgc tctaatccac ttccaccact caaaaaaagc
    32641 cttgcccctc cacagggcta ttccggttat gagtatgtac tataccatgt aaatcagcag
    32701 catagcaaag cattttctcg cccggtaggt ttgcgacctg ccgggcgatt tttgtcgtct
    32761 tttgcggccc ggctgtcccc aaaaaaattt tttgagaaat tttcaaaaag gaggtattta
    32821 gcgggtagct ggcggccttg tcaaagtctt gttagcggaa agggagagaa ccacctaagt
    32881 cccccacaga aagggggtga gaagatggat gctatccccc gcgactatga agcgcggtgc
    32941 atgttcgatg ctttttgcaa gacggtactg cgtaacgagg ccaaaagcta cttggctgaa
    33001 atgaagcgcc gccgtgaccg tgaagtgtca ctaagctctt tgtcacaggc agatttggac
    33061 aagctctgta cagtagatca ctaccccagc gacagcttta cgttttcgtc gcatggctat
    33121 gacctacata tcaacaatga gcttgttgcc gaagcctttg ccgcgctgcc cagcatggag
    33181 cagagtattt taatcctgca ctgtgttctg gatatggcag atggtgagat cggcggcctt
    33241 gtgggaatgt cccggagtgc cgttcagcgg cacaggacaa ataccttatc ggagctgcgg
    33301 aaacagctaa aggcgttgat gccgaaggga ggttagacgc ggatgaagaa cccgaactac
    33361 aagggcattg agcttttgcc cctttcggtg atcgaggccg cccgcgctgg ggatgccgga
    33421 gccgtagagc gcgttttgca gtattacagc ggttacatga acaagctgtg tacccggacg
    33481 ctctatgacg aaaacggcta tccgcatgtg tgtctggacg aggccatgaa gcgccgtctg
    33541 gaaatcaagc tcatccacgc tatcgtcacg aactgacgaa ccggccccgg cagcatgaaa
    33601 cggcttaccc tttccccgtt tcggtgtttt cccggtggcc tgatcgcacc ttgataaata
    33661 tgcccgcaag ataacggcgg cgcatcatag ggcatacgga cacattctgt ctgtgccgag
    33721 ccggacggct ggtgcgccat gatacttttc cctacgggaa aagcggagcg aggaacacca
    33781 cgccgcaatg tgagcgtggc ggcttgcggg cgacgacgta caggcaggac tatgatactc
    33841 ccttatagcc acagtccgag cgttaaaagc gtcgcaggca atgggtaggg ccgcgtgaga
    33901 accacgcggg ggtgaaagtc ccgtggagct gtgccagcag ccgtccgtct atgcccctaa
    33961 atcacacaaa cctttgaatt tgtgaaaggg ggctgcatta tgaaccatga tgtgcctatt
    34021 tgggaaaaat acacgctgac gattgaggaa gcgtctaaat atttccgtat cggagaaaac
    34081 aaattgcgta agctggccga ggaaaatccg gcctctggct gggtcattat gaatggcaac
    34141 cgcatccaga tcaaacgcaa gcagtttgag aaaataattg acactttgga cacaatctaa
    34201 tagtgaaaaa gggccgcaga tatgttataa taatttataa gcatatatgc ggctctttcc
    34261 gtcatggaaa ggagcatgac gagatgtcag aaaaaagacg agacagcaaa aatcgcgttt
    34321 tgcggtctgg agagagccag agaaaagacg gacgatatgc ttacaaatat gttgatacct
    34381 ttggaaaacc gcagtttgtt tactcatgga agttagtgcc tacggataag accccggcag
    34441 gtaaacggga ggatatttca ctccgggaaa aggagaaaga aatccagaaa gaccttgacg
    34501 acgggataga caccatcggc aagaaaatga ccgtctgcca gctctacgcc aagcagatca
    34561 ggcaccgggg caatgtgaag cacaacacca aactgggccg ggaacggctg atgcgtattc
    34621 tggaacaaga tcggctgggg agctgcccga ttgacagtgt gaagctgtcc gacgcaaagg
    34681 aatgggcgct tcggatgaaa gaaaagggcc tttcttataa gaccatcaat aacgacaagc
    34741 gttccctgaa agcggctttt tacaccgcca tacaggacga ttgcatccga aaaaacccgt
    34801 ttgacttcca gcttagtgac gttctggacg acgatacgga accaaaggtg cctcttacac
    34861 cagcacagga agaaagtttt ctgtccttta ttcaaggtga taaggtttac caaaagcatt
    34921 atgacgcaat cgttattctg ctggggacag ggcttcgcat ttcggaactg tgcggactga
    34981 cggacaaaga tttggatttt gaaaaccggg taatcatcgt gagccaccag cttttgagaa
    35041 ataccggcgt cggttactat attgacgaac ccaagaccca aagcggcgtc agaaaaatcc
    35101 ccatgaatga ggaagtgtat caggcgttcc agcgagtgat aaaaaaccgc aaaggtgcaa
    35161 agccgttcat tattgacggg tatgccaatt tcctgtttct caaacagaac ggctatccca
    35221 tgacggcggt agattatggc gggatgtttg gcaggcttgt gaagaagtac aacaagagcc
    35281 atgaagaagc gttgccgaaa acgacgacgc cccatgctat gcgtcataca ttctgcaccc
    35341 ggttagccaa tgcgggaatg aaccccaaag ccttgcagta cattatggga cattccaata
    35401 tcaccatgac gctgaactat tatgcacacg ccacattcga ttccgcaagg gcagaaatgg
    35461 aacggctggc agcctgacac aaggccggtt ttactactcc atttactact tttgaggggg
    35521 aaatggtgag aggtaataag aacatttgta agtatctaac aatatcaaaa atgccggaaa
    35581 agcccggaaa cacgggctat accgacattc aagaacttct aaaaagataa tctaaaatcc
    35641 catataattt tcctcctaaa aaaatagcac aatggcaaag atcgtaagag agatcataag
    35701 ccccaatgaa tgactaaaaa gaaaagcaga atcacatgcc atatcatccc atatttcttc
    35761 aagaaaataa ataagcggga aaaagggaag gaatagtaga acatcgatcc agcaccattt
    35821 ttttcttctt ttgaaataac ataaaacaat aaacatgaac gtgcagggaa gtaaaaacaa
    35881 agctttactc ataactaaca aaataccagc tccttttatt tttttctccc ccacattcaa
    35941 agagtaacaa tggtatgtac ttaataatag aaaaatggat caacttgtat gaataacagc
    36001 tgaaaagatc tgcaccaaat aaaaaacttc cagccaaaac tgactggaag tttatttttt
    36061 tctgaaatat tctaacacaa atatgaaaaa gatggccgaa gctaataagc cgatttcgta
    36121 gcaaaacaat gagataccag agtcgtaata ataaaatcct ctaatcttat ggataaaata
    36181 gatcatcgga caagcagata agagtaagta tttgttaggc cttttgaata agtaaaagaa
    36241 agcactggtc attatgataa atggtatcca aaacaaaagt ttacttaaga caatcaaatg
    36301 atcaactccc atatttttta ccaagagaga tcataacatc tttatcgtaa aaacaaaata
    36361 tttttttgct cattttgaaa atttaaacat actcgttctt atccaaatat ataaaaatcg
    36421 cccctcattc atcgagaggc gataagttct aatttaactc aatttttttt gtttcttttg
    36481 gctgataagc tgttttaggt aataccaatt tcagcacacc gtttttaaag gttccagtga
    36541 ttttttcttc atcaacatta ggaagataga atgaacgttt gtaagagacc gaatgtcttt
    36601 ctttccgtac atagttgcca tcttctttat cttctgtatg ggactcatga ttggcggaga
    36661 tcgtcaaagt attatctgaa tattcaactg tcgtgtcttc tttgtcacag ccaggcatat
    36721 cagcagttag tttgtattct ttttcatttt cgactaaatc tacttttgga taacttgaaa
    36781 cacctaaaaa atcattgaat gctggactaa acacgtcatt gaaatcaggg aacatgtcgc
    36841 gaatgctagg tacatttgcc atttttgatc atcctttcaa taagtatttt ttatttatcc
    36901 ctatttacgt aataactcta ttttgaaaaa aatgcaagta taatggttag ctttgtgaat
    36961 atttcatcta atacgataca aaggctatct ttctaatttg aaaaagggat cattaaaata
    37021 ataagaagaa aatatgtcaa aaggtaaaaa agtaaattct tctatccaaa tatagaaaaa
    37081 ttgaatctag aaaaccgccc gacaataaat ttcattaact cagttgaccg aaaatgaagt
    37141 agataccaaa aatttatcaa gagagcaagt agagaagtga gtatattcat aagagaaata
    37201 gctgtaacga attattaggt taatgcaaat gcttatttat actccgtata actttctcag
    37261 aaaaaatgat accaataatg acttgctagt actgtaaatc cgtataatat catctaatca
    37321 aaatggtgtt ccatttgcat ctgtcatcgt aatcgatcct tcgggtgaca ctcgataaaa
    37381 accaacgctt ccagatcctc cttgggaacg gatttgtttg ctggaagctg tgaacaaata
    37441 atctcgatca attttttgat aaaagctaat aacaatatcg tcactttgta attcggaacg
    37501 gtgggcaata agaaatagaa gtgctttgtc agagttttct aatggaagag aaggtacagt
    37561 gctttcttgc atttcagatg ttgaagaaat gctaaacgac tgaatacttg attggctatg
    37621 ttgcgaatct acattaccag tagaagtatt agtaatggaa gtagtagaag tacttttagt
    37681 tgaaccaacc tcagttgttg aaatggctgc tgaagattct ttaacagaat tctttgtttt
    37741 atatccacag gcagaaaaaa gtattacagt tcccaacaag cctgcgtaaa tccctttatg
    37801 catgatagct cctcctaaaa tagattatct ttattcagta tatcacttaa acaaagaaaa
    37861 gcagatggtt taaaatgaaa aaaccttccc aataaaggga aggttcatga agataataac
    37921 ttttttaata attatagctt tctaatatct ttcatcaact tttctagtaa tcattgggaa
    37981 aaatttcaag cagtagatcg cacaaatacc tacgacgata taaatgatct tcgcaaaaat
    38041 agttgttgaa ccaccagcaa tcatagctac taaatcaagt tcgaacaagc ctaccaacag
    38101 ccagttcaac cctcccacaa tcaataaagt taatgcaata gcatctaaag ttttcattag
    38161 aattctcctt tcttaaatga taaaacaatt atatatcaaa aagagaaaca ttgcttatat
    38221 aacgctcagg aattttagca atctatgcaa aaagatgaaa attttttttg ctcttccatt
    38281 agtacacatt ttttagctga agctgtaaat ttcatgtctt aatttttttt agtgagcttt
    38341 tatactggat ttgtaagaaa aaagaaggag aggatcacat atgtcggatt ggttggatat
    38401 tgcaggaaaa gtagtaattg taactggagg ttcctcagga attggaagaa gtatcgtcga
    38461 aaatttgttg aagcagaatg cacaagtagc gaattttgat gtaactgaat gccgtataca
    38521 gcatgaaaac ctactatctt taaaagtcga tgtgtcttct aaaacggaca tagaagaagg
    38581 gatatataaa gtaatgaaac atttcaagac gatcgatggt ctagtcaata atgcaggaat
    38641 aaatattcct tctcttctaa tagatagaaa tcatccaaaa agcaagtatg aattatcaga
    38701 acaagttttt gataagatga tcgctgtcaa tcaaaaaagt gtatatttga tgagccaagc
    38761 agttggaaga atcttggtgc aaaagggatc aggagtgatc gtgaatcttt cttctgaatc
    38821 aggattggaa ggatcagaag gacagagctg ttatgctgct acaaaagcag cgatgaacag
    38881 ttttactcgt tcttgggcaa aagagttagg aaagaggaat gttcgtgtgg taggtgttgc
    38941 accagggata ctggaagaaa ccggtttgag aacacaagaa tatgaagaag ctctttctta
    39001 tacgagaggt ataagcgtcg aacagctgag aaacggttac agtcgaacaa gtacgatccc
    39061 tctaggaagg agtggtaagc tgcaagaagt ggcggatcta gtctgctatt atctttcaga
    39121 aagatcaagt tatatcactg gagtcacgac taatatttca ggaggtaaaa caagaggata
    39181 aaggataggg gggacgcacg tgacgctagt aaacagatgg taccaattat tgaaattact
    39241 agtcactcac aagaaagttt caatccagga agtgcaaaaa gaaatcaaaa ccagtaatca
    39301 aaccataaaa aaagatattg gggagttgaa tgaagaaatt gccggtattg caaaaatcat
    39361 ccaaaaaaac aaacattttg aacttgaaat ttatgatttt gatttttttg atgagatcat
    39421 gcaaggaaaa ttgaaaacag ccagtgattt caattcggca tccaaaagaa tcgcttattt
    39481 actaaatagg ctgatcgaaa cagaggattt cttacgtatg gatgatttgt ctgaagaagt
    39541 cggtgtcagc agaggaacag tggtcaagga tctaaagaca ttaaaagaga tgatcaatga
    39601 ttttgatgta aagattacag gcacaccaaa taaaggacta agaataatag gagatgagct
    39661 agaattacga ctacttttat tttattttgt ttctccctac ttttcagaga cgaaaacaga
    39721 acagtttcta gaagaaaaac aagcaatcaa acattttcag aagaagacga atgctagtaa
    39781 acaagaaatc acccttttaa cgaaagttat cggtatttct ttgaatagaa tctctagtaa
    39841 ctatctgttg aagaagccca tcaatcgtta cagtgggtgt tttgaatata tccaagaatt
    39901 caatgaactg atcaatcagt tggaagaaat ctatgaacta actttgagcc aatatgaaaa
    39961 agattttatc agttttcctt tgaacatcat caacacaagt ataacgatga taaggaaagc
    40021 taactctgat ttgcgcttat atttcgaccc catgatgatg cgtattcgac gattagatct
    40081 cattgatctg gatgagtcct tcttatatca agagatgaaa cagcacctct ctttattgat
    40141 aaatcgggta atttttcgtt atcgattgac tgatttattt tatggtgaga tagaaaaaaa
    40201 gtatcctttt tcttaccaaa tcgctagcga atgcatacaa gcattagaag ctatcttgca
    40261 acataagatc tctaaagtag agatcagcta cctaacgttg tatttggagt tagcatttcg
    40321 atatcaaaaa gagcattttt cctctaaaaa agtagccatt gttcatacga caggaaaagg
    40381 aacagcatta atgatccaaa gacaaatcaa aaggatattg gggagggata tacaaataac
    40441 acatgtttca gaagaacaat atgaaaaagt agatctaaac aaatatttcg ctgtttttac
    40501 aacgattccg ttaaaaaatg taaatgaaga gacaccggtg atccatttga ctaatctttt
    40561 tgatgactct tggttaaggg cacaatggca aaaagcaaaa aaaaagcgat tagccgggtt
    40621 tcattctact gtttttttct atcaaatatg gaaagaaaaa aagacgtatc aagaatattt
    40681 aaacaaatta gtcgctcctt tgatcagagg ctattatgtg gatgaagaat ttgaaaaaag
    40741 gatcttgaaa agagaatatc agcaaagcac atttgttaac aaagaatttg cttttcctca
    40801 cacaaccaac cagctatctc aacacattgt tttatcagta gggctaataa ctgatcaagg
    40861 tttagcagaa acaggaggaa atggagttat ttttttattt gccatacctg aagaaatgac
    40921 ggctgaagtt gagaatgaat tatttgagct atacgatatc ctatttgaac tcataaaaat
    40981 gggaatagat gagtttattg aattagcacc gacacaagaa tcatttttaa aactaatcaa
    41041 aagtaaagga gagagacttc atgaatgata tgtatctatt catagttttc gcagcttcag
    41101 cttatgtgct gcaagcagtt atcagttgga agcaactaaa gcatttcaat caaacatata
    41161 gcgaactgcg aagaaaagga aaagtagcga ttggtaaacg acctgggaaa atccgttcag
    41221 gcacgattgt tatgctagct atagacgatc atgatcaagt tttagaagtc agaaaaatgc
    41281 aaggggttac atctttggca aaatttcatt cattacctgt ctatgcgggt gaagatatcc
    41341 attacatcga tcgttaccat ccctcagttc gagcggaaga tcgtttgaca caagcagctt
    41401 tagaaaatgc cagagaagta tacttacgaa tagaggcagg aaatgaaaaa agtgaacaac
    41461 cttcattgcc ttttattgct atgctcaata attttcggat atggaaaagt acgatcaaag
    41521 aaaaaaggag tgacaaacga tggatatcat aacaaaattt gctgagggat ttatgaggct
    41581 gttccaaaca ggtgcagaaa cattcataag ctggatgaca ggaatcgtac cagttgtctt
    41641 gatgctgatg gttgcaatga atacgctgat tgctttttta ggtgaagacc gagtaacgaa
    41701 agtagccaaa ttatcagcga aaaatccgct tactcgttac cttgtgttac cgttcttatc
    41761 tgcttttatg ttgggaaatc ctatgtcatt tacaatggct cgtttccttc cagaatacta
    41821 caaaccaagc tattatgctg ctcaagctca attttgtcat acgagcaatg gtgtattccc
    41881 ccatattaat cctggagaat tgtttgtatg gatggggatt gctcaaggga tcgaaacctt
    41941 agggctaaat tcgatggagc tggctatccg atacttgctt gtgggactgc tgatgaactt
    42001 tattggtggt tggataactg attttactac tggatttgta tgcagacagc aaggaatcgt
    42061 tcttagcaaa aaagtagagc tttcagttga ttagagaaag gagagtttta aatgtatggt
    42121 gatattaaga tcgtaagagg aaacggcggg tatggaggtc ctttgattat taggccgaca
    42181 aaagataaac acaagttcat ctatgtcaca ggtggaggtg agaggccaat gatcgtagat
    42241 aaaatagaag aactgacagg tatggagtct atcaatgggt tcaaaacatc aatacctgat
    42301 agtgaaatcg cgcttgcaat cgttgactgt ggagggactc ttagatgtgg aatttatcct
    42361 aaaaaaggga taccaaccat caatatcgtt tccacaggaa aaagtggccc attagcacaa
    42421 tatatcactg aagatattta tgtttcagca gtagggttag aacaaataca gccactaatg
    42481 gaaactgatg ataacaaaga aacagtaaat actgcatctc cagataaaaa gtacaaatat
    42541 gatacttcta aaaagataac cgagcaaaaa gcagagcagc aaaactggat agcaaaaatt
    42601 ggaatgggcg cgggaaaagt agttgctaca ttcaatcaat cagcaagaga agcagtagat
    42661 acgatgatcc ggacagtgat cccttttatg gctttcgttt cccttttgat tggtgtgata
    42721 caaggttctg ggatcggtaa tgtatttgct aacattatgg cacctttagc aggaaatgca
    42781 gttggattaa caatcattgg ctttatttgt tcactgccat ttttatctcc tttgcttggt
    42841 ccaggggcag ttattagcca agtgattgga acattgatcg gtgtagagat tgggaaagga
    42901 aatattcctc cccaattagc attaccggca ctatttgcta tcaatactca aaatgcatgt
    42961 gattttattc cagtcggtct aggtttggaa gaagcaaaag ctgagacagt agaagtaggt
    43021 gtaccatcag ttctttattc aagatttctt aacggcatcc cacgagttat cattgcttgg
    43081 gtagcaagtt ttggattata tagctga
//
LOCUS       DAZKCW010000024        43050 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000024 DAZKCW010000000
VERSION     DAZKCW010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.024"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            212..604
                     /locus_tag="ACG84Z_001363"
     CDS             212..604
                     /locus_tag="ACG84Z_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFP9162214.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACG84Z_001364"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACG84Z_001364"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFP9162215.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACG84Z_001365"
     CDS             2698..2943
                     /locus_tag="ACG84Z_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162216.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3165..4775
                     /locus_tag="ACG84Z_001366"
     CDS             3165..4775
                     /locus_tag="ACG84Z_001366"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFP9162217.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4752..4964)
                     /locus_tag="ACG84Z_001367"
     CDS             complement(4752..4964)
                     /locus_tag="ACG84Z_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162218.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5067..5936
                     /locus_tag="ACG84Z_001368"
     CDS             5067..5936
                     /locus_tag="ACG84Z_001368"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFP9162219.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="ACG84Z_001369"
     CDS             6101..7372
                     /locus_tag="ACG84Z_001369"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFP9162220.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="ACG84Z_001370"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="ACG84Z_001370"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFP9162221.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="ACG84Z_001371"
     CDS             8763..9026
                     /locus_tag="ACG84Z_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFP9162222.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="ACG84Z_001372"
     CDS             9471..9920
                     /locus_tag="ACG84Z_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9162223.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="ACG84Z_001373"
     CDS             9977..11395
                     /locus_tag="ACG84Z_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFP9162224.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="ACG84Z_001374"
     CDS             11395..12255
                     /locus_tag="ACG84Z_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFP9162225.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="ACG84Z_001375"
     CDS             12429..13202
                     /locus_tag="ACG84Z_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFP9162226.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="ACG84Z_001376"
     CDS             13349..13714
                     /locus_tag="ACG84Z_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFP9162227.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="ACG84Z_001377"
     CDS             complement(13862..15070)
                     /locus_tag="ACG84Z_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9162228.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="ACG84Z_001378"
     CDS             complement(15089..15367)
                     /locus_tag="ACG84Z_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162229.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="ACG84Z_001379"
     CDS             15560..16216
                     /locus_tag="ACG84Z_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFP9162230.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="ACG84Z_001380"
     CDS             complement(16658..17455)
                     /locus_tag="ACG84Z_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFP9162231.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="ACG84Z_001381"
     CDS             complement(17452..18636)
                     /locus_tag="ACG84Z_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFP9162232.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="ACG84Z_001382"
     CDS             complement(18661..19908)
                     /locus_tag="ACG84Z_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFP9162233.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="ACG84Z_001383"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="ACG84Z_001383"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFP9162234.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="ACG84Z_001384"
     CDS             21888..22202
                     /locus_tag="ACG84Z_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFP9162235.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="ACG84Z_001385"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="ACG84Z_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFP9162236.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /gene="tmk"
                     /locus_tag="ACG84Z_001386"
     CDS             22887..23531
                     /gene="tmk"
                     /locus_tag="ACG84Z_001386"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFP9162237.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="ACG84Z_001387"
     CDS             23546..23875
                     /locus_tag="ACG84Z_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFP9162238.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="ACG84Z_001388"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="ACG84Z_001388"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFP9162239.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="ACG84Z_001389"
     CDS             24863..25687
                     /locus_tag="ACG84Z_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFP9162240.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="ACG84Z_001390"
     CDS             25680..26027
                     /locus_tag="ACG84Z_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFP9162241.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="ACG84Z_001391"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="ACG84Z_001391"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFP9162242.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="ACG84Z_001392"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="ACG84Z_001392"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFP9162243.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACG84Z_001393"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACG84Z_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFP9162244.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACG84Z_001394"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACG84Z_001394"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFP9162245.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="ACG84Z_001395"
     CDS             31684..32451
                     /locus_tag="ACG84Z_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162246.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="ACG84Z_001396"
     CDS             32441..34483
                     /locus_tag="ACG84Z_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162247.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLITGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="ACG84Z_001397"
     CDS             34764..34913
                     /locus_tag="ACG84Z_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFP9162248.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="ACG84Z_001398"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="ACG84Z_001398"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFP9162249.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="ACG84Z_001399"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="ACG84Z_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFP9162250.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="ACG84Z_001400"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="ACG84Z_001400"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFP9162251.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="ACG84Z_001401"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="ACG84Z_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFP9162252.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="ACG84Z_001402"
     CDS             39330..40412
                     /locus_tag="ACG84Z_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFP9162253.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="ACG84Z_001403"
     CDS             40412..41215
                     /locus_tag="ACG84Z_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFP9162254.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="ACG84Z_001404"
     CDS             41285..42025
                     /locus_tag="ACG84Z_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFP9162255.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="ACG84Z_001405"
     CDS             42036..43040
                     /locus_tag="ACG84Z_001405"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFP9162256.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
BASE COUNT        13845 a         7521 c         8999 g        12685 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttattta caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt ttgtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa cgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa
//
LOCUS       DAZKCW010000025        38063 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000025 DAZKCW010000000
VERSION     DAZKCW010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.025"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(40..531)
                     /locus_tag="ACG84Z_001406"
     CDS             complement(40..531)
                     /locus_tag="ACG84Z_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162257.1"
                     /translation="MTDKTGNLPKLAPKTSQTKSKKDEKIKNAVKKKSVKESSSLLLD
                     IPMSTFDEILDDNTDETSVKIASHVGMNSQNDSFYHLLNSLRELEDKKNQVIASKAPD
                     LTTDLDAEIIQVKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISEQKK
                     SDD"
     gene            614..1999
                     /locus_tag="ACG84Z_001407"
     CDS             614..1999
                     /locus_tag="ACG84Z_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HFP9162258.1"
                     /translation="MKKSKKTFGTLLIAVMQIIGITASLITINPQVTHADGIATYDAQ
                     FNCSTEGSQGSSGSGKDSDGNETGSGAVSGDVAKNIDDIYKFMNGEYGLSGATIAGIL
                     GNWKQESGNDPRTVEGYYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVNWAKKN
                     FGGAWWTTEAQLDFMFKGDGGFVAILKDYALNASDDVVANAVAFHKNWEISADSESAV
                     VAVRGGNAKEIWEYMKSKGMDGAKDVSKINKIAGGTSTGGGSNNSSSSASGTVEDACA
                     TTDDANSGSGSMGKEGKINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFN
                     GIYQGQCTELTWAYMSQLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDG
                     WLWAVGDAGHTGVVIAVFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFS
                     GVGKAKFEIEK"
     gene            2022..2549
                     /locus_tag="ACG84Z_001408"
     CDS             2022..2549
                     /locus_tag="ACG84Z_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162259.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSDKEKIEYYKPFTFKLTNFGIKTSSSGLYEVLTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            2536..3099
                     /locus_tag="ACG84Z_001409"
     CDS             2536..3099
                     /locus_tag="ACG84Z_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162260.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            3521..4258
                     /locus_tag="ACG84Z_001410"
     CDS             3521..4258
                     /locus_tag="ACG84Z_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162261.1"
                     /translation="MADRKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(4275..4691)
                     /locus_tag="ACG84Z_001411"
     CDS             complement(4275..4691)
                     /locus_tag="ACG84Z_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162262.1"
                     /translation="MNKKRKLSVLITLISILTILSGILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            5083..6330
                     /locus_tag="ACG84Z_001412"
     CDS             5083..6330
                     /locus_tag="ACG84Z_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFP9162263.1"
                     /translation="MNMKKNSLGMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            6600..8990
                     /locus_tag="ACG84Z_001413"
     CDS             6600..8990
                     /locus_tag="ACG84Z_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFP9162264.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKIKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGAFKQEGITVKDDGQTFEYTATNTLKKGVVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGISVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDRNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            9039..10874
                     /locus_tag="ACG84Z_001414"
     CDS             9039..10874
                     /locus_tag="ACG84Z_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFP9162265.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANRTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            10949..11806
                     /locus_tag="ACG84Z_001415"
     CDS             10949..11806
                     /locus_tag="ACG84Z_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9162266.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            11796..12905
                     /locus_tag="ACG84Z_001416"
     CDS             11796..12905
                     /locus_tag="ACG84Z_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9162267.1"
                     /translation="MKNKILLFLTLICTLVLTIYPASQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKPETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVLGALASLKVLILLIKEFRKA"
     gene            13244..14044
                     /locus_tag="ACG84Z_001417"
     CDS             13244..14044
                     /locus_tag="ACG84Z_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162268.1"
                     /translation="MVEISKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETLKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIEGDTYPDAKSLATSDFKT
                     FYGYLMGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYADDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            14150..14938
                     /locus_tag="ACG84Z_001418"
     CDS             14150..14938
                     /locus_tag="ACG84Z_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162269.1"
                     /translation="MSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWISAVGEEN
                     IEFEIKNMDDLKAKFPFIASKLSQFAEEKSWNELVSFSEKIYDITQEDECVSWEMNNQ
                     YKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYAEYLKTE
                     RDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALSQYSSDE
                     EVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            15051..16478
                     /locus_tag="ACG84Z_001419"
     CDS             15051..16478
                     /locus_tag="ACG84Z_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HFP9162270.1"
                     /translation="MMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFDFIYPIV
                     ESTYSTHGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYSFEDPIP
                     HFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANANKHKFT
                     KEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESGYYVKGE
                     REKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRVVADAGY
                     KTPKFVHFLSHLKLYPILPYTVPHGVKGMFRKKDFVYDAYFDCYLCPNNQPLLFSTIT
                     RDGYRTYKSNPKFCRSCPLLKNCTLSTKHQKIVTRHVWADLMDELEHQRHTALNREIY
                     KKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLWKAKKPM
                     AFYLKFLQRLTKRSWQLSHSFLSTV"
     gene            16709..17578
                     /locus_tag="ACG84Z_001420"
     CDS             16709..17578
                     /locus_tag="ACG84Z_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFP9162271.1"
                     /translation="MKKKEFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            17598..17945
                     /locus_tag="ACG84Z_001421"
     CDS             17598..17945
                     /locus_tag="ACG84Z_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162272.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            17958..19220
                     /locus_tag="ACG84Z_001422"
     CDS             17958..19220
                     /locus_tag="ACG84Z_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162273.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            19300..20676
                     /locus_tag="ACG84Z_001423"
     CDS             19300..20676
                     /locus_tag="ACG84Z_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFP9162274.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMIIKLVNGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAESRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANSSSKEPSIEKKSTFALKLEKNKEEKEKQGAKTLEKLQAEKLEKVLKALDK
                     ADSEPQTSNNTNNEQPISSKTKPKTTDPKVSVNVTITTDKSEKKQVNGTTSPIMQKML
                     KAKKQVHK"
     gene            20673..21302
                     /locus_tag="ACG84Z_001424"
     CDS             20673..21302
                     /locus_tag="ACG84Z_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162275.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRTKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            21321..21800
                     /locus_tag="ACG84Z_001425"
     CDS             21321..21800
                     /locus_tag="ACG84Z_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162276.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            22359..22958
                     /locus_tag="ACG84Z_001426"
     CDS             22359..22958
                     /locus_tag="ACG84Z_001426"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFP9162277.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            22974..23450
                     /locus_tag="ACG84Z_001427"
     CDS             22974..23450
                     /locus_tag="ACG84Z_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162278.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSEDSKSMRDLLITYLNEHEFEQTKVKKKNKK"
     gene            23467..24369
                     /locus_tag="ACG84Z_001428"
     CDS             23467..24369
                     /locus_tag="ACG84Z_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162279.1"
                     /translation="MLFTLLGYLCLVLAFFGAIAIFVGQFQANNPIMRNIGIGIVIIS
                     LIVFGATKIFGSNDQQFGISGVDNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDDK
                     KASDDVLATIKPSQSQFEVFYTVKENNPVRKLTLVFNVDGEEYYKDVKINKASTKKIV
                     ESAKKEVATEESTTESSSTVEVELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQRINVTLFNAVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGSDLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            24442..24636
                     /locus_tag="ACG84Z_001429"
     CDS             24442..24636
                     /locus_tag="ACG84Z_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162280.1"
                     /translation="MVVNKEKVRKYVTLKIASVEYLEKRAKEEEKTRGKKVTVSELLE
                     ELIESDQTIRRAFTNRSVKS"
     gene            24741..25169
                     /locus_tag="ACG84Z_001430"
     CDS             24741..25169
                     /locus_tag="ACG84Z_001430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162281.1"
                     /translation="MIIQKFDWKMKLGISLVILGFIIFLGIKAQKNQSTFETMSSQII
                     EECSKIYYCENKTEESNGFYYIDQPHDVVIKMESHEVNEWIQRSTNVSKKLERYSQTF
                     LSKVIFSNCKNEETSQRVASSLENLKFSVSKKEKFVDLRK"
     gene            25404..25991
                     /locus_tag="ACG84Z_001431"
     CDS             25404..25991
                     /locus_tag="ACG84Z_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162282.1"
                     /translation="MENNNDIRYFSIGERVTTVSELSKDYRDKEGTIISLKKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVFPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            25991..26890
                     /locus_tag="ACG84Z_001432"
     CDS             25991..26890
                     /locus_tag="ACG84Z_001432"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HFP9162283.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNVADATNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            26890..27804
                     /locus_tag="ACG84Z_001433"
     CDS             26890..27804
                     /locus_tag="ACG84Z_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162284.1"
                     /translation="MNNNEKILHVLDSFETIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKKAMELNEDRRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPANSGIGIVLKAIDEEEIEDFIPAEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCEGYEVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     DARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNASNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKEAE"
     gene            27856..28071
                     /locus_tag="ACG84Z_001434"
     CDS             27856..28071
                     /locus_tag="ACG84Z_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162285.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLQQFWLNNFSYKDFIKEKANRLY"
     gene            28261..28515
                     /locus_tag="ACG84Z_001435"
     CDS             28261..28515
                     /locus_tag="ACG84Z_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162286.1"
                     /translation="MKKEELIDMFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLISDDVNFAHDVVGIQNHIDRENKRMGDGFLPRYSSL"
     gene            28727..29743
                     /locus_tag="ACG84Z_001436"
     CDS             28727..29743
                     /locus_tag="ACG84Z_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFP9162287.1"
                     /translation="MGLVLLSPSVSAESSISMYRMYNPNSGEHLYTRSVGERDNLKRY
                     GWHYEGVAWQAPTSGSPVYRLYNRYNGEHFYTVDAGERDKISHTGWTYEGVAFYSYNG
                     ANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNSAPNPTPAPAPS
                     NEKLLNVPVIWQGNTMLCEGASLLEGLHYKGVATNQNLTSFVNYMPRANDNNPYHGYS
                     GEWRYNVSGTYQGIMPDPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGNPVVTWITYN
                     YASPQFKQMPWGRAVWNGHVVLVDGFKNGAYHVVDPVFGAKWINASTYERAFNVTGMA
                     VAVR"
     gene            29918..30148
                     /locus_tag="ACG84Z_001437"
     CDS             29918..30148
                     /locus_tag="ACG84Z_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162288.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEEEYKENIPENLQGS
                     ERYEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            30184..30408
                     /locus_tag="ACG84Z_001438"
     CDS             30184..30408
                     /locus_tag="ACG84Z_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162289.1"
                     /translation="MIDISLIEKLLFSNKYTAKELATRWQISESAIKAYRQNKGSVGW
                     RDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            30625..31500
                     /locus_tag="ACG84Z_001439"
     CDS             30625..31500
                     /locus_tag="ACG84Z_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162290.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKEE
                     ITKMKPVIKILDNKE"
     gene            31510..32304
                     /locus_tag="ACG84Z_001440"
     CDS             31510..32304
                     /locus_tag="ACG84Z_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162291.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNIL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            32492..33451
                     /locus_tag="ACG84Z_001441"
     CDS             32492..33451
                     /locus_tag="ACG84Z_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162292.1"
                     /translation="MGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFN
                     EAYSRIMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMLFLVNFEGTAK
                     EGTYANPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKK
                     GLLKEYFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETNTFDKYSMYNRAYS
                     SMVAGVFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTI
                     SKEEVEKALEFKNKGFENKGSFGNSKDEVKGVVIDDDFEFDFD"
     gene            33484..33804
                     /locus_tag="ACG84Z_001442"
     CDS             33484..33804
                     /locus_tag="ACG84Z_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162293.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            34059..34952
                     /locus_tag="ACG84Z_001443"
     CDS             34059..34952
                     /locus_tag="ACG84Z_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162294.1"
                     /translation="MRTHYIYLEDKIIDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EDEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHEELSEGTEKYTIADMVNEVETLLASFFENGHVNDEWRKEEPKRVNAYI
                     ARLKRFIDKYKENSDKFSKDK"
     gene            34972..36606
                     /locus_tag="ACG84Z_001444"
     CDS             34972..36606
                     /locus_tag="ACG84Z_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162295.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNNGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMSLTIKRIYDLLYVYKH"
     gene            36635..37804
                     /locus_tag="ACG84Z_001445"
     CDS             36635..37804
                     /locus_tag="ACG84Z_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162296.1"
                     /translation="MTKKIEVYVDGSQEERDSFFDFFWKNSREYVKALNLVYKQLMFE
                     ELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKLDKAKAELSKLRNEKNKEAR
                     EILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASKDFGNDFIGIVTGQRTPRIY
                     KNRSKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLGSKPRKARDVASVLQHIMDG
                     DYKLNQSNLIFDGRKLFFNLTISFEKRYNELEFKEGNELIVNFADLCSGECLVNNKSV
                     MSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRKLDQDRWEAIKKRESNFVKT
                     YNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLKEQLVNKGKRYGIEVRS"
BASE COUNT        14344 a         5222 c         7699 g        10798 t
ORIGIN      
        1 tccttaataa acaaaatttg aaaaaagagt aatgactatt tagtcatcac tctttttttg
       61 ttcggaaatt gaaatatgtg gagcttgtat tggtttagtt aggattgctt ggctatatgg
      121 agctagttct ttatcaaaac catcaaaata ggttttcagt agcgatttaa ctgatcgctc
      181 atcttgtttg acttggataa tttcagcatc caaatcggtt gtgaggtcag gagcttttga
      241 tgcgattacc tgattttttt tatcttccaa ctctcttagg ctgtttaaca agtggtaaaa
      301 agaatcattt tgactgttca ttccaacgtg agatgcaatt ttaacagaag tttcatccgt
      361 attgtcatca agtatttcat caaaagtact cattggaata tcaagtagta acgaggatga
      421 ttcctttact gattttttct ttacagcatt tttaattttt tcatcttttt tgctctttgt
      481 ttgagatgtt tttggagcta gtttaggtag attacctgtt ttatcagtca ttaattagct
      541 tttcctttct acttatttat gttattataa tatcataata acataaaaat gtacactttt
      601 gggggcgcag ttattgaaaa aatcgaagaa aacgttcggc acgttgctta tcgcagtgat
      661 gcagataatc gggattacag cgagtttaat cacgataaat ccgcaagtga cacatgctga
      721 tggaatagct acttatgatg cacagttcaa ctgttctact gaaggctcgc aagggtctag
      781 tggatcagga aaagatagtg atggaaatga aacagggagt ggtgctgtat caggtgatgt
      841 agcaaaaaat attgatgata tttacaaatt catgaatggg gaatatgggc tatcaggtgc
      901 tactatcgca ggtattctag gtaactggaa acaagaatca ggtaatgatc ctcgaacggt
      961 agaaggttat tacggtgatg gacagagaga agttgacttt atcaaacaat tcactgatgg
     1021 tctgatgggt attggctatg gtcaatggac agcaggtcgc catactgcat tagtaaactg
     1081 ggcgaagaaa aactttggtg gcgcttggtg gacgacagaa gcgcaattgg attttatgtt
     1141 caaaggcgat ggtggatttg ttgctatatt aaaagattat gctttaaacg cttctgatga
     1201 tgttgtggca aatgccgtag cgtttcataa gaattgggaa atttcagcag attccgaatc
     1261 agctgtagtg gctgtacgtg gtggaaatgc aaaagaaatt tgggaataca tgaaaagcaa
     1321 aggcatggac ggagctaaag atgtaagcaa aatcaataaa attgccggag gaacaagtac
     1381 cggtggtgga tcaaataatt catcaagctc agcatcagga acagtagaag atgcctgtgc
     1441 aactacagat gatgctaatt ctggttctgg atcaatgggt aaagaaggaa aaattaacgg
     1501 taaaaaaggt caagtaatag cgaatatgac ttatgaagaa gctttgaaaa aatatgggaa
     1561 agcgatcacg ctaccaaaat tcaaagaacc agattggtca acttcacctt ttaacggaat
     1621 atatcaaggt cagtgtacag agttgacgtg ggcttatatg agccaattat acgatgggaa
     1681 tcaaccgact actggaaatg gtggctatgt atgggaaagc tacaaatcgg caggagcgaa
     1741 aataacgaac aaaccaatcg taggttatgg gtttagtgct tcggatggat ggttatgggc
     1801 tgttggcgat gcagggcata ctggtgtagt tatagcggtg tttgaagatg ggtcatttct
     1861 atgtgctaac tttaatgttc caccaaccca agctccaaca aggggagttt cggtaacttt
     1921 gattgatgga gtggacggat cagataatgt gcatttcttt agcggtgtag gaaaagctaa
     1981 atttgaaatc gaaaaataaa ttggaatgaa ggacgatata gatgaatagt aaagtgaaag
     2041 atacaattat catttctttg ctttctggta tgttattagc actgcttgtt ggaatcctat
     2101 tcttcaataa gcagaatcag gacatagaag ctgaaaaaca cagtgtgcat attgaagata
     2161 agctgacatt ctttaaagag gttaaaccaa atgaggtgga tggattacgg aaagatttag
     2221 aaaatgatat tcaagaaatg ttgaatggat cagttcaaaa taagtttgca gatcaatcag
     2281 gtgaagaatt tttgagaaaa ctatttattg tcacaggtaa accaccaatt actgataaga
     2341 gtagtgataa agaaaaaatc gagtactata agccttttac ttttaagcta acaaactttg
     2401 gaattaagac atctagtagt gggttgtatg aagtattgac cgattttgaa gttcaataca
     2461 atggaaaaaa agtgtatgat accacattaa ccatcacact aaataatgat aagaaagtga
     2521 ctgggggtgc tttttatgca aaatcatgaa atcactactg ctaaaaaggc gattggaata
     2581 ctttccataa ttgtgatcct ttgttgtgtg gtactatttc aaaagaaaaa tgcttatgat
     2641 aataatgtca aagaattgga agaccttaaa agtaaacaaa tcgaagtagt caagaataac
     2701 cagaaagtga aagctatgca ggaagcccaa tacaaagaat tggggaatgc tgaaatcaag
     2761 gaacaaagta ggaaattctt taatttattt tacaactgga attcatggga aaaatatacg
     2821 aagaatatga aggaaataca aaaagaattt cctcagatag taaagtctag tcctgttgat
     2881 atttctggca cgatggtagg cactggtaat agtccaatat ctagctatac tgctgattac
     2941 tatacaacaa atcaaaaagg taaaatggtt gaattgatta cacagacaag aaatactcca
     3001 acaacagcaa caacaacaat ttggcgtgga gtaacaagca taggagaaaa tcaattgttt
     3061 tacttggagg atttagatag ctatgtaaga gcagagtaaa ataaaaaaag agctaacggt
     3121 accaacgtta gctctttgtg ctgacgatga taacaaaacc taccgaaaaa ggattgtttc
     3181 atcacaaaca caaacagaaa agaattgata aaaaacccga acctcagaat ttttattaat
     3241 caattcattt agattataat aaattgagct gaacattaca atacgtatat gttgtaaaac
     3301 gtaaaaaaag tcaaaagtaa atactttctt aaaaagtcaa ataaaactat taaagacaat
     3361 atatatggtt tatttgacat aagaaaatgg tctagatgat aattgtaata tagaattgta
     3421 gacttaaata aagcataaaa taccttctat gataaggtat agctcttaat tttaagcagt
     3481 tttagatata agattgaaag taaagtgggg gagaataata atggcagatc gtaaattaga
     3541 aaagttatta gaagaaacgt ggaatccaaa agaatttagt gaatttttta tggagaattt
     3601 tgaaactgac ttagcagtga ttgttaaaga tgctcttaga gagcaagggt atcctgaaac
     3661 tgcaaactat ataaacatta attttacttt gtatactgaa aataaaggaa cttgggattt
     3721 ttgggctact ttagcaaata aggagttaag tgataaatca gacacaggaa ttcgtaactt
     3781 ttttgaatca aacagagatg attatatgta tgctaacaat caaaataaat tgaactttag
     3841 agtagagttt gatgaaacac ctgaagaatt tatagaaaga caaccgccta aagaaaatgt
     3901 agcaaaggta ttggaagatc gttggaattc agatgaaata gtttcaacaa ttagcgaact
     3961 aggcggacaa tatgaaccgc tagtagaagc ggttagagaa gagctaagac tgaataagtt
     4021 tcctgatgtt caaaatattg atgtttctca aattgaaata aacgtcaaga tcacgaataa
     4081 acttgattat ggtagttggg cagatatagc attagaaaaa tacatctact caacgttaaa
     4141 agagtttatc gaaaatagaa tggatatcat gtatctacag catccacagt atttaaactt
     4201 tggtgttgaa atagctacac ctcttgaaga atggaaaatg gagcaagggc ttgactagcc
     4261 tttgctccat ttttttattt tacaaatgaa tacagttcgt cgtttttacc aagaatgatt
     4321 gtttgcccaa ctttgagatt gtcaggtgat ccttcagcgg tttgtaagga gaacgttcca
     4381 ttgaacttat cggataccgt tataggtagc tttaattctg atccttcctc atctttgaga
     4441 attgctgttt ttcgttcatc aaaataaaca gtctttatta aataattttt cgtagtgatc
     4501 tcagcagatt tgtctttttt tgtagtagta ccagtttctt tagaattaga ggtattttct
     4561 acgactattc catctttggc atttgagctt gtgtttattt gattgaatat tttcagcgac
     4621 aagataccgc taagaatagt caatatagaa ataagtgtaa ttaatactga taatttcctt
     4681 tttttgttca tttttcttaa cttccttttt tgttttgatt agttagatat tccttatcta
     4741 acaagcattt ttaggctatt aaatgaagat aaaccccaaa aaaatattgc aattatgaca
     4801 gtgcaatggt actattatta tacaataaat tttgcgaaag gggtaggtct aaatcgcaaa
     4861 caaaaagaaa ttgaacctag acaaatacaa cttgtatacc gcaagggaag caagtttgat
     4921 tttgggtaaa ggtagaaatt atgttacaaa cataattaac tattatccaa atcgtttgcc
     4981 taaaggttcg ttcaagaaag tgggtgacaa aacctatatt ataacggaag aaggaataga
     5041 agcattgcga tcacaaacag aaaataaaaa caaaaagaag gaatgaatat gaagaaaaat
     5101 tcgcttggta tggttttatt tgcatcagct gtacttgcgg ggttatcagt accagtaacc
     5161 tcacatgctg atgaatggac tgcaaacaca ccggatcaaa tccaaattac aacaggacaa
     5221 tcaagttatg cgttcaaaaa aggagatact atttggtcaa ctgtagagaa gcttaaaagc
     5281 ttaggttaca agactactgt tgctgagttt gccgaattga acaatgttga tttggcaaaa
     5341 ggagaacaac ggactatccc aattggacga actttcaaca tcagtaaaga tacattaaca
     5401 gttaaggaag cagatggcga agtagttagt caaactgttc aaaaggataa acctgatcct
     5461 gttgaaaata cggagcaaga gaacaaaaaa tccgagacta caaaagaatc ggaaccaaca
     5521 gcaaacactt ctgataagac agaaacaagt gcttcaagtg ttgatggagc aagttcatct
     5581 aatacaaata attctacaag tgagaaagaa gcatcacagg gaacaagtga aagtagcact
     5641 acggaagctg atactggaac atcaacaaat aactcacaat caacatcaaa tgatgcaaat
     5701 gaatcaacca gtacatcttc tagtgatcaa tcacaaacag gttcgagtga tgaaactgac
     5761 agttctactt caccaagtaa acccgaacaa ccaactaatg ttgtgctagg cgttccattt
     5821 attagtcaag gtaacacaat gctttgcgaa ggaacatctt tgctagaagc gttacattat
     5881 aaaggtgttg caacaaatca agatttaatg acttttgtta aatcaatgcc actatctcct
     5941 gataataatc caaataatgg tttttctggt gaatggagac acaatgtgga tggaacttat
     6001 caaggtatga atccggctcc tgtagtttca tggggtgttg ctaatggcgg aaatgttgta
     6061 gatatttctg gttcatcggt acaaggatta aaagatgaga ttgtaaatgg aaatcctgta
     6121 gtagcatggg taacttatgc ctttgaacct gctcaacata aatcaatgtt ttggggcgat
     6181 gctatttgga atcgacatgt agtagccgtt gatggattta aagacggttt ttaccatgtt
     6241 gtcgatcctg tgtttggggc aagttggatt aatgcaggat catttgaaac agcatataac
     6301 gtatctcaat tagcggtttc ggtacgttaa taaaagagat cgtttatata ctaagtagtt
     6361 aagtatagtc tttatttgcc cttacttaac tacttagaaa acttgttgct catggtgggt
     6421 agaactaaaa ggggtgatgc tatgaataat agagcgttga aacatcttgc tttcaacgaa
     6481 aaaagtgatt aataggtgtg gtgattttaa cttaggaatg ggcgcgaagg tcattaccac
     6541 accgacatat cgtggctcat tttcttcgcc taactggtat aaagaaggag taacgagaga
     6601 tgaagcatga aaaaacgata attttaaaat caaaaataat ttattgtttt gcgactttag
     6661 taatggtgtt atctacgctt ataatgcctt tttcagcaat aagagctgaa gcagatgtca
     6721 caaaaccgac aagtgcaaaa tttacagaaa ctggcgtaaa aacagacggt tatattaggg
     6781 ttaatatgcc gaatcatcca aatgaatgga tgatttcaag tcaatttaaa gattctcatg
     6841 gaaatattgg atattgtatg gattcagaat tgccatcccc aacaggaagt ggagccggaa
     6901 gcttgaagta caagggagct ggcagtgatg agttctatcg tatgtttaaa ggtggttttc
     6961 catcaaaaac agcaaaggaa ctgggtgcag gaaatgatac agaagcatgg tatgcaacac
     7021 aattagtttc atgggtttta gccggaaact ttaaagtttc acagattgta tggtcacatc
     7081 caaaccatac cgccgcagaa acagctcgtg taaaaaaagc atttgaaaaa atttatgact
     7141 atgctaagaa tggaaaagat acgcccaaca ctgagttttc tatcacagct tctaagacag
     7201 ctgacgaagg aaaatatcac actttcacat ataaaacagc atcaaataag actggtaatg
     7261 cgaagctcac ttttacatca gcaaaacctg ctggtatgaa gatttatgat gcagatggta
     7321 aagaaattac taacaacact gtaaaattaa attcaagttt tactattaaa gtacctgtga
     7381 ctacaccaag tggtactttg tcatttaaag gtactgctaa tgttagcacg accaatcctt
     7441 ttacttttga tggacgaggt gtgtatcaag atgccgtagt tatgatcact acttcagaaa
     7501 caaaggactc taaatctttg agtgctaaat ggacaagagc tgttggtcag gtaacagtta
     7561 agaaagttga tcaagatgga aatgctttaa aaggagcgga gttcactcta actgacaata
     7621 acaatgctaa atctgttaag acaaccggag atgatgggtt agctacgttt gatttgcaac
     7681 aaggcttaac atacagctta gaagaaacaa aagttcctga aggttatcaa ggttcattta
     7741 aaaaggatgg tattactgtt aataccgatg gacaagaatt tagttacact gctacgaaca
     7801 caattaaaaa aggtaaaata aaagttaaaa aggttgacca agatggaaaa ccattagcta
     7861 atgctgaatt taccttgacg gatgattcat cccaaacaca agcagaaaaa acagatgaaa
     7921 acggacttgc aagcttcgat attgtagcaa acaagaccta cagccttgaa gagaccggag
     7981 taccaactgg ttatacaggc gcattcaagc aagaaggaat taccgttaaa gatgatggac
     8041 aaacttttga atatacagct acaaacactt tgaaaaaagg tgtagtaaaa gttcataaag
     8101 tcgatcaaga tggaaaacct ttggcaaatg cagagttcac tttaaccgat gaaaaaggtg
     8161 caacacaagt agaaaaaaca gatgaaaatg gacttgcaag cttcaatatt gtagcaaaca
     8221 agacgtatag tctagaagaa accggagtac cagtaggtta cacaggtgca tttaagcaag
     8281 agggtatcag tgttaaagac gatgggcaaa cttttgaata tacagctaca aataatttga
     8341 aaaaaggtgt agtaaaagtt cataaagtcg atcaagatgg aaaaccttta gcagatgcag
     8401 aattcacctt aacggatgaa aaaggtgtaa aagaagttaa aaagacagat gcaactggtc
     8461 tggctacgtt caacattatt gcgaacaaaa cttacaactt agaagaaaca aaagtaccaa
     8521 caggttacac aggcgcattc aaacaagaag gaattaccgt caaagatgat ggacaagtct
     8581 ttgaatatac agctaaaaac actttgaaaa aaggtgtgat caaagttcat aaagtcgatg
     8641 atcaagggaa agcattagca aacgcagaat tcactttgac ggacgacaaa ggtgtaaaag
     8701 ttgtacaaaa aacggacaga aatggcttgg caacatttaa tattgttgcc aacaaaacgt
     8761 acaaaatcga agaaacacaa aaccctaatg gttatacagg gaaatggtct aaagaaggca
     8821 tcaccgttgc tgacgatgga caaacctttg aatatacagt aattaatcac cttgtacctg
     8881 aaacagtaag aacaggcgga atcggtacat cagccttcct tcttgtattt ctaattgcag
     8941 gattgagtat ggtgctactg tattatcgag aacagcacaa agcaaaataa aaaagtgtta
     9001 atggaaaaga agtaaatatg aaaaaagaag gctgacgtat gaaatcaaaa aaaatttttt
     9061 caaatttaat gctatttggt actttgctag gagtgggatt gggcgcaagc tcaatctctt
     9121 ctagccttgg actagggggg caagtagcat atgcacaaca aaactataat tatcaaggaa
     9181 ctggaacgat tcatatccat aaagtaacaa atactaatgg ggatgggaac cctgtctcag
     9241 atattgataa caaagggaaa gaaatagctt taccaaatgg tgtaaaacct cttgaaggcg
     9301 ttgagttctc ttatgtgaaa cttactaaag atgaagctaa atccttggga tggacggata
     9361 gtgatactac aaaaggtcaa catattgatg atgctaaagc acgattatta ctaaacaaaa
     9421 aatacagtga agtaagtaga atgaagactg attcacaagg gaatatagac atacctatac
     9481 aagtaaatac agacgattta acagataact tgtatttgat tgttgaaaca ggaacagtca
     9541 aaggtgtagt tgaagaagcg tatcctatga ttgttaacgt acctgaacta aacggatcag
     9601 atgatcaata ctttaattat gatgtacatg tctatcctaa aaactatttc caattaaact
     9661 cagcagagct tgataaaaaa gacgaagatg gaaaggctct tgccggaact gtttttgaat
     9721 tgcgaaaaga tgatggatct gatcaggttg ttggaactta taaaacagac agcacaggta
     9781 aattaactgt ggatggtttg gaattaggtg actattattt cctagaaacc gatttgggaa
     9841 cagatgctaa tagaacaacc tatttactag atggtaaaaa attcaaattt agcgttaaac
     9901 gtggggagac tgctaaagta gttcttgatg ttaccaacta caaacgacct gtaattacta
     9961 aggtaattga taaagaaacc gttgatactg gcgaagatgt tcaatataca ttgaaaccat
    10021 caattcctgg taatattggt aattacgaaa aatatgttgt caaagatgtt ctaggtgcag
    10081 agttaactta tgattcatca gaagtgatcg aaggaatgac tttagatact gattacagta
    10141 tcgaacgtga cggacaaacg acaaactatg tctttactga atcaggtatg gataagcttc
    10201 agaaacaatt tgatgcaggg gatcgcttct ttacaatttt gatgaacgct catactaata
    10261 gtaaagctaa aatggataca ccacttaaga atgatgtttc aacgatctac aacaatggat
    10321 atgaacccga agacgaaaca ccagttgatc acgcttatac aatcattggt gatcaccaat
    10381 tcattaaaac agatggagat acaagcaaag cattgagtgg agcaaaattt gtagtgaaga
    10441 acaaaattga tccgaataaa gttacttacc taaaacaaga tccaacaacg aaagctgtta
    10501 cttggattgc agataaatct aaagctactg aattcgtttc cggatcagac ggtaagttcc
    10561 aaattgaagg tttgcaatat acctatgatg tagattttga taaacaaggt aatccaacaa
    10621 tcacagataa aaaaatcaat gattatgctc ttgaagaagt tgttgctcct tcaggatata
    10681 caccaactag aaacgatgtt ccatttgtgg tatcgaatga tgatgcttct agcgaagtaa
    10741 cagacatcaa gaaccttaaa acacctgaaa cagttcgtac aggtggaatt ggaacagtag
    10801 tatttctagt ggttgcaggt gtggcaggaa cagggctata tgttgtctac aaacgagaac
    10861 aacacaaagc ttaatgaaat aaaattccct agagtgtttt tggctctagg gtttcttttt
    10921 aaaaagtgtg tgaaaagtag gtatgagcat gaaaaagaag aatatcaagt tgatcatctt
    10981 aaaaattggg atgttgctat gtttaggagt aggtctatat cctgtaatta ctcaggctta
    11041 tacctactac caaactcaac aaacactaaa ctcctataag gaaaaatatg atgaagcttc
    11101 tgaaaaggag aatgaagaag tcttcaagag atattcagaa gttaatagga aacgaaaaga
    11161 cacagaacaa acctcagtca cgattcctga agataataac aatattccgt caaatggaaa
    11221 tcttcagaag gataaattag gtgaattagt gggtgaaatt cttataccaa agattaatgt
    11281 ggatttgcca atttatgatg gtgtaaacga tttccaacta tcagcaggag caggaatatt
    11341 aaccggaact gattatccaa ctggtgggat tggaaaccat tctgttatat cagctcattc
    11401 aggcattcct aataaaaaat attttacaga tttagagttg ctcaaacttg gtgataaatt
    11461 ttttattgat atttcaggga aaaaacttgc ttatcaagta gatcggataa aaacaattct
    11521 accaaccgaa tttgaggatt tgcttcctgt ggcaggaaaa gattatgtaa cacttatgac
    11581 atgtacacct gttggagata attctcatag gttactcgtt agaggggtta gcatacctta
    11641 ccaaaaaagt attgttgaga aagaaaagaa gaaagaagat ttaaaggtaa aggcgcagat
    11701 gaactggtat cctatcgtag ttgtaggggt tttattaata atagctgtga tagtcattat
    11761 taaaaaaata gtagcaaaga gacgaggaat gaaaaatgaa gaataaaata ctactttttt
    11821 tgactcttat ttgcactttg gttttaacaa tttatcctgc aagtcagctc tatcatcaat
    11881 tcaaaacaaa agagaatgtg gcggaaatcc aagagaaaat tgagaaaaaa caaactcctt
    11941 caaaagagga agtggcaaaa aaagtcgaac aaataaaatc gaacagcggt aaccaaggat
    12001 tagacaatac tcagaaaaca gataaaggag tagacaatac tcaggaaaca gacggtggat
    12061 catttgatat tcgtgaagct gaaggaaagg tcaatccata cacaggagat gttttttcaa
    12121 aaaatcaaac gaaagatttt gaaccatcta cctattcagg agcggttggt tatgtctata
    12181 ttccaaaaat aaatgtgcta gagcttttgt ttctaggcgc ttcacaggag catttatata
    12241 gaggtgtggc acaaatgagt gctactagtc tacctttatc aggtaaaggt catcaaacag
    12301 taatagcagg tcatcgtggc ggttatacgt caccacaatt tctttatgtt gatcaattag
    12361 tagccggaga ccacatttat atagattatc ttggtgaaaa agcagtttat acggttttcc
    12421 gaacagacgt tattagaaat tacggtcaga attcaacact gactgatatt cctgatttag
    12481 atatgttaac actttatact tgtcatccat atcctcagaa ctacgatcgt ttattagtta
    12541 gaagtctaag agatgaaaaa gcaaaataca tcacgccaca agtaacagtt ggcaataccg
    12601 catacgctga tgccattgat agtgaatccg tttcagataa gccagaaact gttacatctt
    12661 ctaatgattt atttgaggat gttgatcgtg ccaacaagga attagatgga aataatgatc
    12721 ttaatattcc ggaacaaggt agcgtagaga tgcaagacag aacgtttgct gaaaaggcaa
    12781 gttcaatatt tacaggaatt accaataaac atcagaaaat gcttttagtc atttggactg
    12841 tattaggagc attagcaagt ctaaaggttc ttattctttt aatcaaagag tttagaaaag
    12901 cataatgaag attataaaaa ttgatagagt acagtaaaaa gggattgata ctattattga
    12961 tctctttttt attttgaata gagctagatt cacttttaaa taaaatcaaa actgatctta
    13021 attccaaaga aaaagtcaag aaaaaaatac aacaaatttt tttatcagaa tatttatcag
    13081 aatattatta gaaaagataa actcaaaagc ttaatttaat agggttattg gttgtattta
    13141 gaaataatgt atggaaaagc tataaagcaa tagataagat gtagaaaatc ttatttgtga
    13201 atgaaaaaca agtcatcgta aaatattaat aggaggtgta gtaatggtgg aaatatcaaa
    13261 aacagcttta gactcattag ctaaactatt tagtagcagg tttgatggtg cagaatttgt
    13321 tgaatatcta agccaaaacg aaagtggaaa aactctgatc gaaacactga aaaaagacta
    13381 tttgaatgaa aatgactttc cgacatggac gaatattgaa gatgctacat gggatgtagt
    13441 gtgtacgata tattctcctt gggtaacgat tgctgatttt gttttagata aaattgaagg
    13501 ggatacatac cctgatgcca aatctcttgc tacaagtgac tttaaaacgt tctatggtta
    13561 tctaatgggt ctaataggca atggaataga tttgaaagtt acgccaaaac aaacacctga
    13621 agaaattgaa aaagaaaaag gagaggttca aatggcttat gcagatgaca gagaaaaagt
    13681 aaaattattg gaaggtaaat tatctgaaga agaacttgga aaaatggtgc aagaaatcaa
    13741 tgaagacagc aactattttc ctgaattgaa ggtatatcaa aacgacgaag atttctttaa
    13801 tgaaatgttt agtaatagtc catgggaagc agtgagtaaa acaaatttag gagaatggaa
    13861 ctttcaagat gatctagttg catttagcaa tgatgggtat ttacgatcat attcagaaag
    13921 tgagtataga gctgaattaa aaacgtatga aacggatatt ctgatgagct atttaaatct
    13981 attagagagt ggtcagggag agttaagaga taaagttgaa gaactattaa aagaagagct
    14041 atagggatta tttcaacata aacacaagca gaaaactacc aaacaaaacg taccatgcaa
    14101 aaagccggtt taaccggctt tttgctctat tatgagagga gatcaaacca tgagtgcaac
    14161 aaccgatatg gctttagaag cagtaataaa agataataca ggaaatgtcg aaaatgtaga
    14221 agactttagc gatattgcaa tcaatctttc agcatggatt tcagctgtag gagaagaaaa
    14281 tatcgaattt gagatcaaga atatggatga cttaaaagca aaatttcctt ttatcgcatc
    14341 gaaactaagt caatttgccg aggagaaatc gtggaatgaa ttagttagtt tttccgaaaa
    14401 aatttatgat attacgcaag aagatgagtg tgtttcatgg gaaatgaata atcaatacaa
    14461 gaaaattgat gctttcgtca aatcacgtat agaaggaaca gcttttgagt ttgaaggtat
    14521 agataccgca gataattggt taaataaaga atcctttatt aaaagtatag cggatgatct
    14581 tgaaaaacaa tggtctaagg aagactatgc agagtaccta aaaacagaaa gagatacaga
    14641 ggtgaaagaa aaactcactg aggtatgttt ggatgaacat attgatccca atatcgtaaa
    14701 acaagaagac tatgaagtgg ttattgataa agttcctact gattttgagg aagttgtaaa
    14761 gtatatagtt gaagaagcat tatcgcaata ctcttcagat gaggaagtgg acgaagaaac
    14821 tgttcgtacc agagtttggc aactggtttt tgatgacaaa gattataaat atttgagtga
    14881 tcaaaactcg gttaattgga gtgtacgatt attaattgat caaaatgata ttgaataaaa
    14941 tagagctgaa aagctctatt cagactgtag acaaactcct aaattgggag tgttgtttgc
    15001 agtttttttg ttttatactc attgtataaa ctattctggg agtgattcta atgatgagaa
    15061 aacaatcgat tgaaggtaga aatcaatttg ctatgttaac aattgatgat cttgtaccta
    15121 aagatcactt agttcgaaag attgatgctg cgattcagtt tgatttcatt tatcccattg
    15181 tagaatctac gtattcgacc catggtcgtc ccagtattga tccagtggtc ttaattaaat
    15241 tagtatttat ccaatattta tttggtatcc gttcgatgag acagactatt aaagacgttg
    15301 aaacaaatgt tgcttatcgt tggtttttag gttattcatt cgaggatcct atcccgcatt
    15361 tctctacttt tggtaaaaac tatgttcgaa gattcagaga aacaacttta tttgaagaca
    15421 ttttctctca tattctagaa caagctgtaa aagctggctt cgttacggaa gacaaccttt
    15481 atattgattc tactcatatt aaggcaaatg ccaataaaca taagttcaca aaagaaatga
    15541 cctacggtca agctaaagct tatcaagatg aattagaaga tgaaataaat aaagaacgta
    15601 ttgctgtagg aaaacgtcct tttacatggg acacagaaag tgagttgagt cttcaaaaaa
    15661 taagtcattc agatccagaa agtggttact atgttaaagg tgaacgagaa aaacaatttg
    15721 cttattccgc gcatacttcc tgtgaagata atggttttat cttatctaca ttaatcacac
    15781 caggaaatgt acatgacagc caagtcgcaa tcgatctggt caaacagtcg aaaagagctt
    15841 ttccaaatat aaagcgtgtt gtcgctgatg caggatataa gacgcctaaa tttgttcatt
    15901 ttctgtcaca cttgaaactc tacccgattc ttccatatac tgtacctcat ggagtaaaag
    15961 gaatgtttcg taaaaaagac tttgtttatg atgcctattt tgactgctat ttatgtccca
    16021 ataatcaacc gttgttattt tcaactatca ctcgtgatgg ttatcgaacc tataaatcaa
    16081 atccaaaatt ctgtaggagt tgtccattac ttaaaaactg tactttgagt acaaaacatc
    16141 aaaaaatagt aactcgacat gtttgggcgg atcttatgga tgaacttgaa caccaacgcc
    16201 atacggcgtt gaatagagaa atttataaaa agagaaaaca aaccattgaa cgaatatttg
    16261 cagatgcaaa agaaaagcat ggtatgcgtt ggacgaaata tcgaggtctc gaaaaagtcg
    16321 ccacgcacac gatgcttacg tttgctgcca tgaatttaaa aaaactagcc acatggctat
    16381 ggaaagcaaa aaagcctatg gctttttatt taaaatttct acaaagacta acaaaaagga
    16441 gttggcaatt aagccactcc tttttgtcta cagtctgaat agagctgaaa agctctattt
    16501 tttttgataa aaaaactagc tattttttta aaaataattt ggttcaaaat ttattttttt
    16561 aacttgataa ttttttgcca tcctttttta aattggctat atatcaaggt ttatagtggg
    16621 gataaataaa aatacatttg acaaaattta caatatagtt tattatatat ttatcttatt
    16681 atgataacac aataaaagga atgatggtat gaaaaagaag gagtttagtc gatcgttgtt
    16741 aggaatttta gttttagttg cggttggtct tagtggcaag ggttactttc agaataacag
    16801 cactcaggaa catgattttc agatcaaaag tagtgttcag gtaggtaata aagcagacag
    16861 tgaatcaaaa gaatttttag ggatacgtta tgatccaaac aaatatccaa ataatatcgt
    16921 aaacattaat gatgggaaat atacactgac aaaagaagac catgaagcat tatcagaaaa
    16981 aggcagtcaa accttttggg taaattatgc agatttagat caacttggaa gagcaggaga
    17041 tgttgaagcg ttgatcacct atgatgctgt aaattctcac tcatctaaaa atgtggaacg
    17101 tccatctttc aaaagttctg tccatattgc aggagaatac aaggatggag tatttgatca
    17161 agagagagat acttgggtcg gcaaagattc aaacaatgaa atcactcagc tagaaggata
    17221 taaaggttat ctctataaca aaagtcattc attagcatgg tcgctaggag gagatatgga
    17281 ggtacacaat ttaacacttg gaacgagagc gcaaaatgtt gggaaaaatg atcagaatgg
    17341 agggatggct tactcagaaa cgattgtacg tgatgcaatc tataaaaata agaatgaaaa
    17401 ggtattgtat aaagttgatc caatttataa agggaatgaa ttggttcctc gtggttctca
    17461 tgtcgaagct ttctcagtta acgataatgg aaaaacggta aaccttaatg tttatgtatt
    17521 taacaatcaa aaaggaatca acatcaacta tcaaaatggt acttgggtaa gagattagaa
    17581 attgagaagg tgaagaattg gaaacaataa gcatcaatgg attagataaa tcagttgcaa
    17641 atcgaataaa aaaaggaaat ggctactatc ttctgaagaa gggtaaatat tcagttgcta
    17701 gagagttaga aacaatgagt atcgtgtatg tagctaagaa tcattttgac gtagaacagg
    17761 ctatttttga tccagattct gaaataggga aatgtgttga attatcagag aaaactgtta
    17821 gtacaaaagg ggcgatgatc attgagagag aaatgttaga cgaaatcaga gtaatcattc
    17881 ctaaagatac gcagatgtgt gaggacagca taagtgacga tgaaccaaaa tcagaaagaa
    17941 aataaggaga tattcagatg agcgaaaaat ccattgaatt aaaggaatat aagcgaagcg
    18001 atggagaaaa atattatcct gtagccagtt tttctaaatc agtatatctg gttggacgtg
    18061 cattggtagt tggtgcaatt ggcatatata ttttgcattg ggtaacaaag gttgtacaac
    18121 tgcttgtaga taccttagta agtattcttg tctcgttaaa tgatgttaac ggaacagatg
    18181 atttaggatt aaaagaaatg tttaaagagt tactcaatgc gttttttccc aattatttaa
    18241 gttattcata taatgtacaa agcttttttg caaagctaca cttggtagac atctctattt
    18301 tagtattaga agcaggaacg gtattctttg ttggatattt ggttactttg atgttcaggc
    18361 atcactatgg agaacaaaga ccattttttg atgatatgga aagtagaagg ttgaaaagag
    18421 aagctctaga agctatggat gtgaagtatg atccaaacaa gattatagga gatgaaacga
    18481 acaacaaaaa aagaaaacga aacaaaacgc aattagaatc cgatgtgcta tcaacgctta
    18541 aaaatatcaa aatttctgtt catacaagac gtgatctaag tgtcaatgaa gatattcgag
    18601 aatatatcgt aaaaatcccg caaccaaaag ggaagaaagt tagagaaaca gttttacgac
    18661 aaattcaaga tttagggtcg atcctgacaa gagcaacaag cggacgagcc aaatttggtg
    18721 aaaaagaaga tgaagtttca ggcgattatt tcattttccg agcatcagta aatattgaaa
    18781 gagaacgtaa ggaaagagta agtaccaaaa acaaagaaac ggaaagagca acatcttcaa
    18841 tcgcagtttc aaattcacaa ttttcttttc caatcaatct ctttgccgat aattccaaaa
    18901 atatccaaaa ccaaaccgaa aaagctagaa aatatgccga aactcaaaag caatctttag
    18961 aactttatct atcttctgct gacgtacctg caagtctaac agatatgcac gttgggaata
    19021 catctattga atatttgttt actttatctc gtaccagaaa aattcaacta agctcaatga
    19081 aagaagaaat tgaaacttac ttgcatatat caggtgtaat cgtgcggatc aacgcagggc
    19141 gtattcaaat tactttacca ttaggagaaa atgatcgtat tccaattgat gtaccatcaa
    19201 tgatcaatag cgtgttttaa aagacatcac aaatagaaac agaaaataca aactaccagt
    19261 tcacaaacag aaaagtaccg agaaaagtga ggaatagaaa tggctatgaa attattagag
    19321 aaagtcaaaa agagagccga aaaagctgaa tctattttgc tagataaaga acctaatata
    19381 aagcttaatg gaaaattcag tgtcaatatg ttgaacacaa aggctaaaga cccgacagat
    19441 gctatttttg gaattaagcc tgatggcaca attgctcatt tttgcatcag cgaaatgcca
    19501 cacatgttgg ttgcaggaac gacaggatca gggaaatcag tattactgaa tgaaattctt
    19561 gttacagcaa tgtgtcactc aacgcctgat gaattaaaaa taggaattgt agacccaaaa
    19621 agggttgaat ttggaagata caaaaaattg ccgttcatgt tggctgatcc aattacagat
    19681 atggatgaag cttatgattt ttttgaatat cttgtgatct tgatgcatga acgttacaaa
    19741 ctgatggaaa aagcagggtt acaaaacatc acgctatata acgaatatgc cgaaaaaaat
    19801 ggattagata gatttcccta tgtgatctta ttagttgatg aatattcaca gttggttgga
    19861 acacataaag aagtagaagg tttgattgtt caattaggac aaatggcaag ggcagcaggt
    19921 attcatgtta tcttagctac acaatctcct cgatcaacag ttgtcactgg tattatcaaa
    19981 gccaattttc cgtcacgtgt ttgccttatg gtagcaagtg atttagaaag taggatcgta
    20041 ttagatgaag gcggtggaga aagcctaagt ccaaagggag atatgattat taagctcgtt
    20101 aatggaagta tggttagagc gcagggagct tacatcagta acaaagaaat tgaaacaatt
    20161 ttcaatcacc ttagaaatac tatgccagaa ccagaatatg ttgattaccg agcaatcgta
    20221 gctgaatctc gtggtgaggg tggagaagac gaggattttg gtggaattgg taaagctcct
    20281 gtaagaaaat ctgctaaaag aaatttgaac acacctttag caaattcatc atctaaagag
    20341 ccatcaattg aaaagaagag tacgtttgct ctaaaacttg aaaaaaacaa agaagaaaaa
    20401 gaaaaacaag gagctaaaac actagaaaaa cttcaagccg aaaaattaga aaaagtttta
    20461 aaagcattag ataaagctga ttctgaaccg caaacctcaa acaacacgaa taatgaacag
    20521 ccgatttcat ctaaaactaa accgaaaact actgatccga aagtttcagt aaacgtgacc
    20581 atcacaaccg ataagtctga gaagaaacaa gtaaacggaa cgacttcacc tatcatgcaa
    20641 aaaatgttga aagccaaaaa acaggtgcat aaatgatcat tgtcagttct tttttgaggt
    20701 ggcttacgcc atataaatat acagatgaag tagttgtgaa acgaacgaag aaaagagata
    20761 aaaaagcggt actaactcct aaacagatgc ttgatcatgg cattttaggg gtgaaggttt
    20821 tagaagtgaa taaaccgttt gaatcaaata gtgcaagaga aaagttgctt ggagctgaag
    20881 ccgatgtcgc atatttttac catgacaaaa gcaagcatca aatagctatt aaattcaatc
    20941 caaaatcggc atggcggtat caagcaagag atgacttgaa acgtaggaaa cttagaccaa
    21001 tgctctatcc agaaggaaaa gaagcatttg atagaaccca catcgttccc attggttttc
    21061 atggtacaga atcagataac cgcctattag taggttggaa cagcaatcaa aatagagttc
    21121 agatcaataa atttgagaag aaagtaagga aattcaacga tcgaaaaacg atcctatggt
    21181 ttgcagatat ttgtaaacag ccggatggaa cagcaaagtg ggaagcggtg atatttgacg
    21241 aaaatggtaa aaaagtaatg tctgaaacat ggcatgataa agctaaattt gtttggcagt
    21301 agcagtagag gtgaaaaaga ttgctagaac tttttgaagc aaatagaaca ggctttaatc
    21361 aaaaattaga agtgggagaa actatagaat ataaagataa aaactatatt attatcggaa
    21421 tctataacac gagaattaac agaataggtg atccacgtat aaccagtgac ttggtttgtc
    21481 aatctgttaa ctattcacct gatctgacaa gcaggtataa gaaatacgtg ttattagaat
    21541 atagacacaa gattactgat gaaattggtg taaacaacac acgaaacata tttaagatcg
    21601 gaacagtgat tccttatagt aacaacgaag aaaaaatatt ttatcagatt tacggaatag
    21661 aaaagtttga atatgaacat gtcgatctgc tagtgacgta ccaaatgcgt ttaatagaac
    21721 cttggtcaca ggcagaaatt gataaagcag taaaattgaa ccgattatca aaatttaacg
    21781 tattaggaaa tgccttttaa aaatcgcaat acacaaacag aaaaatacca aaaaattagc
    21841 aatgaacgta ggtaagaaca tgacaataaa taataataac cctaaaaaat ataatgctct
    21901 tgtccaatgc tatatcgaaa acaaaattac aatgcaagaa gtcgctgatg aattaggcaa
    21961 atcaaagagc ctagtatcac acgattttaa gcacaatgtt tttccgaacc cgattgagct
    22021 gaggaaaaaa tttcaaaaga gagtttatca agaaataggt aagtggattg atgaagggaa
    22081 tgcaattgac cctttaattg aaaaatatcc ttttttaaaa agcaaaaata aaattcaaag
    22141 gttaattcgt caaggcgata ttcaagctaa agaacctgtt ttgacaacca atgatttggc
    22201 taaaataaat cttcataaac aaattattga agactttgaa aaaaatcttt caacaactga
    22261 aattttaaaa aaatacaata ttccgagagg aaagctaaca tcgactcttt ttagagaata
    22321 tggagaatcg gcagttacta aagcaaagga agtagcgaat gagagaaaaa aacaaaaata
    22381 gtagtcgata cctagtagcg actgtagttt ttgtttgtgt attgattttc ctgtttgatt
    22441 ttttgcagat tggaaaaagc ataattggaa atacattgag tgcaaaggaa atggttgctt
    22501 taggtggttt gtatgaagga cacttgttcc cgaatatatt catttctatc gtttctcata
    22561 ttaacttgta ccatttaatt tctaatttat tgttcttagt agttcttgaa gaagcactga
    22621 atgatcagta tgagtggtta acattattga tcgttttaat catatcagga tttctaggaa
    22681 gcttagttcc ttttctgcta cacagcaaca tcgtaagtat ggggcttagt ggaggtattt
    22741 ttggatggat tgctttattt gcgattgcat acatccgttt tgatagcaag aaacatttat
    22801 tactaagtgt ttttgtatta ttgataatcg gcattttact ggtatctact tttgaatcag
    22861 gcgagacaaa cgtcttgtca catgtaatcg gatttgtctg tgggatgatc ttgggattta
    22921 ttctaaagaa cgtttcattg atcaaacaaa agaattaaaa gggagtgcta aaaatgccaa
    22981 aaaaaaaaga aaagaaaatt ccagtgtttt tgtctgtctc agaaatgtta tcacttcaaa
    23041 tactgttaag aaaaaagatt gaaacaatag acgaagaagt tagaaataaa agggctatgt
    23101 acgaacaacg tgaagcgcta agagaacgaa tccactattt tgatgatata cacactaaaa
    23161 tctatgaagc acgtacaaat cacgaagacg aaagcaaatt aggattagct caacaacgaa
    23221 tatttgaatg gctgaatacg aatactgagc aagaaccgtt aagagcaatt agtaatcttt
    23281 ttgaatttgg aacgaagcat tggtttaacg ctgtagaaaa ggatgctgac ttacaagaag
    23341 cgttcgatac actaagcgag gatagcaaat ccatgcgaga cttattgatc acttatctaa
    23401 atgagcatga atttgaacag acgaaagtta aaaagaaaaa taaaaaatag aaagttgtga
    23461 tgtatcatgc tgtttacctt attaggttat ttatgtttag ttcttgcttt ttttggagca
    23521 attgctatat ttgtcggtca gtttcaagca aataatccga taatgcgtaa cataggcatt
    23581 ggaattgtta tcatatcctt gattgtattt ggtgccacaa agatttttgg gagtaatgat
    23641 cagcagtttg gtatttctgg agttgataat agttatgctc cagattcatt gggaagagta
    23701 gtgatagatg gaacgtttga gaatgtaacg agctacaaaa atgtttcatt gacagtgaaa
    23761 gaagatgaca agaaagcatc agatgacgtt ctcgctacga tcaagccgtc tcaatcacag
    23821 tttgaagtgt tttatacagt caaagagaat aaccctgtac gcaagctaac attagttttt
    23881 aacgttgacg gagaagaata ctataaagat gtaaaaatca ataaagcatc aacgaaaaag
    23941 attgtcgaat cagcgaaaaa agaagtagct acagaagaaa gtacaactga atcaagttct
    24001 actgtcgaag ttgaactacc agataaaatt gattttgatc ctgaaaaagt caaatcgttt
    24061 gaatctgttt ctggttctat ggcagatcgg tttaacactg aagttttcaa agctatcaaa
    24121 actgttaaat tggatactga aaagcaaagg attaatgtta ccttattcaa tgcagttgaa
    24181 tcaatggatc aggataaaaa agttacggtt gcaagagaac tagggaaaag agtaattggg
    24241 ttgtatcgag gtacggcaaa accagattca gacggttcag atttgccagt tcacgtagtt
    24301 tatgaagacg gtaaagtttt tggagactct acagcaaatg aagcactaac gattaaatta
    24361 gctaaatagc cggaaaatta taataaacaa gtggtgtcac accaccatcg cataggtgtg
    24421 acaccttgga gatgattact gatggtagta aataaagaaa aagtaagaaa gtatgttact
    24481 ttaaaaatag cttctgttga atatttagaa aagcgagcta aagaagaaga aaaaacaaga
    24541 ggtaagaagg taacagtttc agagttgtta gaagaattaa ttgagagtga ccaaacaata
    24601 agacgtgcat ttaccaatag gtctgttaaa agttagggtg atactatctt taatttcaac
    24661 caaatttcta atatatgatg aatagtttcc ttgtacaaaa tatctaatta agagataaaa
    24721 gttaggagga ttcattcaaa atgattatcc aaaagtttga ctggaaaatg aaattaggaa
    24781 ttagtcttgt aatattggga tttattattt ttttggggat aaaagcacaa aaaaatcaat
    24841 ctacttttga aactatgtct tctcaaatta ttgaggaatg ttccaaaatt tattattgtg
    24901 agaacaaaac tgaagaatct aatggctttt attatatcga tcaaccacat gatgttgtta
    24961 taaaaatgga gtcacatgaa gtaaacgaat ggattcaaag aagtactaat gtatcaaaaa
    25021 agttagaaag atattctcaa acgtttttaa gtaaagtcat tttttcaaat tgcaaaaatg
    25081 aagaaacgtc tcaaagagta gctagttctt tagaaaattt aaaattttct gtttcaaaaa
    25141 aagagaaatt tgtagattta cgaaaataaa ctatcgaaag tagtatgatt atgatcttaa
    25201 aatatcatct taagagaaga attacgattg tttataggat ttacaaaatg aataagtttg
    25261 aagagtgatt tggtcgcaga ctagatcact ctttttctgt aaaaaaactt tacacttatt
    25321 tttgagtgtg ttaagatttt ttatatagag tgacggtttc ttgtcagagt gaatgataac
    25381 catcaatatt ggaggaataa taagtggaaa acaataatga tattagatat tttagcattg
    25441 gggaaagagt tacaacagta agtgaattat caaaggatta tagagataaa gaaggaacga
    25501 ttatttctct taaaaagaat cgaagaggtg tttggcaata tgttgttgat ttaggggatg
    25561 gcgttacagt tgagtgtaaa gatagtcaac tgatcagaaa tgatggcagt cattccattg
    25621 aaaaagcaat tcttgtattc ccaaaagtat caagcaagat tatgaatgac tggttgcttg
    25681 gaaaatttgg tgagtacaat aaaaaagaaa tcgcagaagt gatcggcaaa tcttatccaa
    25741 cagtattagg gtatctaaaa aagataacga acaaagaagc gaaagttgag gatgttttaa
    25801 cagtaagaga acttcagtca ttaatcgaat atcggaataa acaaataaca aatcctgagt
    25861 accttaaaaa agaagatggt ctattgaaac aattggaaca ggtaaataaa atccggaaaa
    25921 tgcaaaaggt agctccttta agcctagata actttaaaaa aatctatttg aaagagatcg
    25981 aaaaagacta atgtggagtg tcactttacc gtttcaacct gtatctgcac caagaccaag
    26041 tgcaagaagg aatgttgctg atgcaactaa tgacgtagca gagaaaagga tttcaaccta
    26101 ttatgataaa aagtatctcg attatttgaa aaaaataaaa agctttatcg aagatcaagg
    26161 tttgttagat gatgaatttt actcgatcgt aaatgatccg atgggtgcaa ttatggaagt
    26221 ggacttttac tatcagatac caaaaagcta taaaaaagtc tataacatta tgaagacgac
    26281 agcgccagat ttagataatt tagtaaaaag tgctatggat ggtattttca acatctcagc
    26341 tatacgagat agccatatca cagggttaat tgcttttaaa tacaatgtgg caaacgaagg
    26401 aaaaacagtt gtgaggatca agcgatattc agaatttgag tgggatactt ctgaaggatt
    26461 gaacggagat atttgggaag ccacatttga tttcaaacca gtagcaacgc caagaccaaa
    26521 gtctaaattt agaggaaatg ggattatcac ttactatcca aaagagtata acgactattt
    26581 ggaaaatatc aagaatacgc ttaaagagaa agatttggta aatgatcaac tgaaaaaggt
    26641 aatgaatgct cctatggggg ttatagctca gatagattat ttttaccaag tgagaaaaga
    26701 taagaaaaag cttgattcac tgatgcgtac ttcacagccg gatattgata acttagtcaa
    26761 aggaacattg gacggaattt ttaacaagga aattggcatc aaagatagca gggtggtagg
    26821 tttaatagct tttaaataca atacttttga aaagtcgaaa acaaacgtgc gactacagga
    26881 gatgggctga tgaataataa cgaaaaaatt cttcatgtac ttgatagctt tgaaacaatt
    26941 caagaggaac taaagaaata tcgagatgtt ttggaacaaa gatatgattt tgtcaatcag
    27001 caaaagagta atcacatgga tttcattctc aatatgaatg acttgaagaa gaaattagtt
    27061 gaacgaaaag aacaagaaaa gttgatcaaa gcttactttg aactcggtga aaaagaagtt
    27121 aaaaaggcaa tggaactgaa tgaagatcgc agggttttag atcagctgtt agaacaatta
    27181 ttggtgatgt ttcaaaaagg acgaatagat gaggatttaa ttgaagaagg gttgagaaag
    27241 tatcctgcaa actcaggtat cggaatagtg ctgaaagcga ttgatgaaga agaaattgaa
    27301 gatttcatac cggcagagga ttttgaatcg gcaatggaat atataaaata ttacagccaa
    27361 gggatcactg cttttagaga gtttgatcct gaagatgtta ttcatgactt gaacaaccta
    27421 aaagaatggt gtgaaggtta tgaagttgat gattccggtt tggactactt gatcagtatt
    27481 atggaaatcg aagaagagat gccggataag cctgatccaa cagatatttt agaattaatc
    27541 catgatgcta gaaatccaat tgcatacatt tctagaggat atactgtatt ggaatactat
    27601 aagccttata tatcagcgat gaaccattta agacgtgtat taagggaaaa acgtgaatac
    27661 cgctcagtgt taaatgcatc gaatagatta gaaaaagctg tttcagagct agatgcttat
    27721 tatcgtgaac attacctgca agcaggtggt atgccaagaa atacgaaagc aaatatcagt
    27781 aggtatataa aagaagctga gtaggcggag ttagcccata aaatggcaaa aggtaacctg
    27841 aaaggggcgt tttgaatgaa aagggatgtt tttgaattgt acgtattaga acgtctagaa
    27901 gacggcatga tggcacaaga gataattgat gaaatcgatg atatgatcag cagatttggt
    27961 caattggaat tgaatgatgg aaacaaaaat tcggtagtgc tacaacaatt ttggttaaat
    28021 aatttttcgt ataaggattt tatcaaagaa aaggcaaata gattgtactg actaaattca
    28081 cgaggatcag tgatgagagc ttattgctaa gagcagttag gctctttttt gtttgtgtta
    28141 aattatttta ttttacaata cacatttata cacaaaaaat gttgacggat agtacacaaa
    28201 tgtggtagga tatatttgta agcaagttag attaacaagt taaaggaagg aagagcagtt
    28261 atgaaaaaag aagaactaat agatatgttt caaattgttg aacgagcaaa taatatggga
    28321 attatgtttt ttgatcgtat ttctttaaag atggatttaa gcgttgccca ccaagaattt
    28381 aatctacgat taaaagcttt attgatttct gatgatgtta atttcgctca tgatgttgta
    28441 ggtatacaga accatataga tagagaaaac aaacgtatgg gtgatggatt cttaccaaga
    28501 tattcaagtt tatgatttgg cgaaagattc aagagtatgt gtcattattg ataggtactc
    28561 ttgaattaga aaggaggaat gaatttaaga caacaacgat tatgatctta aaacaatcgt
    28621 ttatgtaatt ggcaatctta cgaataattt tcatgcaata atgacaataa aaaatgaaaa
    28681 ggggtaaaat caaatgaaaa aatttttagt aggaattcta ttcacaatgg ggctagtgct
    28741 attatcacct tcagtttcag cagaaagctc tatttccatg tatcgtatgt ataatcccaa
    28801 tagcggagag catctataca ctagaagcgt tggagaaaga gacaatctga aacgttatgg
    28861 atggcattac gaaggtgtcg cgtggcaagc tccaacaagt ggttccccag tttatcgctt
    28921 gtacaacaga tataacggtg aacattttta caccgttgat gccggagaaa gagataagat
    28981 ttcgcacaca ggatggacgt acgaaggtgt tgcgttctat tcttacaacg gagcaaatag
    29041 agttcctgtg acacgcttgt acaacaaata cgtgaattgg caccattaca cgttagatca
    29101 aaatgaaaag aacgtaatta gtaaacaagg ttggaagatt gaaggtacgg gttggtatgc
    29161 aatgccaaac agcgcaccaa atcctacacc tgcacctgct ccaagtaatg agaaattgct
    29221 aaatgttcct gtcatttggc aaggtaatac gatgttgtgt gaaggtgctt ccctgttaga
    29281 gggattgcac tacaaaggag tagcgacaaa tcaaaactta accagttttg taaactatat
    29341 gccaagagct aatgacaata atccttatca tggctattct ggcgaatggc gctacaatgt
    29401 gagtgggacg taccaaggca ttatgcctga tccagtagtt aaatgggcaa aaaatgttgg
    29461 tggtaatgcc gttaatatca ctggttcagg aacgaatggg atcaagaatg aaattcgcaa
    29521 tggtaatccg gttgtaactt ggattactta taactatgct tcacctcaat tcaaacaaat
    29581 gccttgggga cgtgcagtct ggaatggaca tgtggttctc gtggatggct tcaaaaatgg
    29641 tgcataccat gttgttgacc ctgtatttgg cgcaaaatgg atcaatgcaa gcacgtatga
    29701 gagagcattt aatgtgactg gaatggcggt tgctgtacgt taattgatag aattaataaa
    29761 taaatgaaat aagagcttaa ttactgaaat ggtaaatggg ctcttatttt ttagaaaaaa
    29821 ctttttttgt aatacgaatc tataacaaaa aacgttgaat atagtacaca aaagtggtat
    29881 attaaaaccg tagagattat gcgaagaggt gattttgatg aaccaaagaa gaagaaaaag
    29941 gctagaagaa ataagcgagc gactatccga gttaaaggat gagttagaag taattcaaga
    30001 agaagaggaa gagtacaaag aaaatatacc tgaaaatcta cagggatcag aaagatatga
    30061 aaaagcagaa gaatccgttg atcaacttga agaagctgtt gatggtttat ccgacatatt
    30121 agaattgatt gaagatatag ctagctagag atgattaatg aagatttcag gagtgagcaa
    30181 aaaatgattg atatttcact gatagagaag ctactttttt caaataagta cacagccaaa
    30241 gagctggcta caagatggca aatatccgaa tcagctatta aagcctatcg tcaaaataag
    30301 ggaagcgtag gatggcgtga ttggaaagga atcagcattg gaaaagcaga agacataatg
    30361 aaacgtgaag gatttcaagc tgacaatgat tctaaaaaag ttgaatagtt taatagtcgc
    30421 caagaaaagt accagggcga ggggaaaggt agattacaaa ggaaaacact tttaaataaa
    30481 cttcgcaaaa gcatcaggtt atgagtggct agggctatac gaatgtgatg aaaacaaagg
    30541 gctttaatgt caaagaaaac gcaatagggg gggaataaaa tttttaaaaa agatatttat
    30601 gtttggttta atgggaaaaa atatatgact actaacaaaa ggtggtcaga gctagtacaa
    30661 aatacagtta aaaaagtcat gccagatgga tatcatttca actatataca atgctcacaa
    30721 acaactgaaa gtatttattt ttcaatatta aatgagaata gactctatta tttcagggta
    30781 agttcacacc ataggaaaaa gagagaagat aatgttacga catttttatc gggaaaatac
    30841 aatggcttca aagagttaag tgaagcaatt ggtgagtatc taaaaagtaa tagatttgtc
    30901 agaatttctg acaaacatat attgatcttg ttactttatt tgaataatag cttcaaatta
    30961 ttttggagag acgacacttt ctactatatt gagaacggca tggatattta ttctggtatc
    31021 aacggcatat taaaacatta tattaaggcg ttacttcgat atggggttct ttatcaagaa
    31081 gatttaagta accaaattaa gattagtaat tctggaaagt cattactggc aaaatataaa
    31141 aaattgcttt ctcctatcta caaaggaata gatatggaag ctgtaaattc tgaaacttta
    31201 tttaatttag ttgttgatga aaagtttgcg aatgaatttt ttaaaagtaa aaaaattgaa
    31261 agactaaata acctgtttcc tgaaaatgca ataaaagctt atgtagataa taataaatca
    31321 cgattataca actggtttat tcccaaacgg ttgcgaggaa aaatcaaaat tggcgatcaa
    31381 gtgaaagtaa ttaatctaaa tcatactaag atcgttaccg taacggagtt gtatatagct
    31441 gaaaaagaag agattacaaa aatgaaacca gttattaaaa tactagataa caaagagtga
    31501 gtggaatata tggtagcaaa aaagaatact ctaaaagaag cttctgaaaa atatcaagat
    31561 atgaaaagac gaggattaat cccaaaggac aaaaaaggta tatggagaga atttgttaag
    31621 gaagtcagta gtgatcgaag tggcggtgac tttgttggac gatatacagc aaaaggttat
    31681 agcaggcgct taaggatcac tgttgaatat ggaacgaatg aatcagctac agagctgaag
    31741 caaaggtact tagatacacg aagagaagct tcaaaaaaat atgatgattt caagagcaga
    31801 ggtctaattc ctaagaagaa aaaggggatt tggcgtgagt ttttcaaaga agaagatagc
    31861 aatcggaata agggagactt cattggacga tacacagcaa aaggctacac taagaattta
    31921 gggatcaagg ttgaatacgg aactggtgaa agttcatggg aattgaggaa tcgctattta
    31981 aatatattgt tagagaaata taaagcagaa ttattggagt tgttcgatgt taatgatttt
    32041 atcgagatgg ctgaaaagta tggtcatgaa gaaggtttta tgatcaatga cattatggtt
    32101 attgataatt ttacggattt attagcactt gcgaaaaaag caagggattt aagagaaacg
    32161 cagatgtatc tattcagaaa taaaaacgga agaaaccgga gaactgaatc gagtgagatt
    32221 gaagattact acgatgcctt tacacacgat ctgggagcct ttgtagacga gataagtggt
    32281 gtaatgaaca aatatagggt ctagaataaa aaagccggag atgagcagat aaatgggaaa
    32341 caatagcata tacacacctg aaatgcagaa taaaattaaa agacttgtcg gattagggtg
    32401 gatgacaaga ggaaaattag attcttttag tacgatcaaa tatcttttga tggacattta
    32461 ccgtcagaac aagcaaacag gaatacattt tttgggctat gataagccgg aagatgcacc
    32521 tttctttgtt ccaagttcag cctatagagc cagtacctcc ggtagcatgt acaacttgga
    32581 tttgttcgag gaaggagcaa agatgatcga atatgatttc aacgaagcct attcgaggat
    32641 catgagaaat tatcctttgc cgtcaaacac ttatttgaaa gcaaaatata atacagatca
    32701 agctattttg agagcgataa atagaccaaa agtaagaccg tatgaaaatt taaaaacgta
    32761 tatgttattt ttggttaatt ttgaaggaac agccaaagaa ggaacatatg ctaatccaaa
    32821 atcacagtcg atgtttgcgg attatggtga aaatcccaaa acagctaatg agcctatttg
    32881 gttatcggag attgagctaa cacttatcct tgattattat gatattaaag agatggaagt
    32941 actagatagc cacacatttt tgacgaaaaa aggattactc aaagaatatt ttgaaagaat
    33001 cgagccatta aaaactgatc ctgatacgtt gaagctttat aaaaatctta gaacgaaagt
    33061 atttggtgct atcggacaaa aatcattaag agaaggagaa acaaatacct tcgataaata
    33121 cagtatgtat aatcgagcgt attcctccat ggtagcaggc gtatttagag atcgtatggt
    33181 tagatatgaa cagaaatacg ttcatagcgc atatgggcta ttaaaaattc gtactgatgg
    33241 attgtatttc agatccgaag taccagagtt tgaagagctg tataaacttg gagtagttaa
    33301 gaaaaaagtt catacaatat ccaaagaaga agtcgaaaaa gctttagaat ttaaaaacaa
    33361 aggatttgaa aataagggct cctttgggaa ctctaaagat gaagttaagg gtgttgtgat
    33421 agacgatgat ttcgagtttg attttgacta aatactcttt ggaaaagatg gtaggaggta
    33481 aatatgaaga agaaaattgt ggaaggaaat gtaggtgtta ttattctaaa agattcaact
    33541 gactatgcta aatcaatggc actaaaagac gaaaaagttg cacgcatgga taaagattta
    33601 gttgaatttc tgatggatga tacagaaaga ttaaaagggg atcagttttt gagtttaatg
    33661 aaagacaaag gcttaaacac atatggttta tttgattata agaaattagc tatagagtgg
    33721 gtaaaagaag gagaaatatt ttttattgaa gaatgggaag gtactgagaa cttagttctt
    33781 catcagtatc ttttgaaagc ttaatctaag taaaacagtt ctgactagtt atgcttgtca
    33841 gaatttcaaa ggatgttttc cataaccatc atcattcaaa aataaaggat ttgaaaataa
    33901 gggttccttt gggaaatcta aagatgaagt taagggtgtt gtgatagacg atgatttcaa
    33961 gtttgatttt gactagattt ttttgcaagg tttaagagta aacaaggtaa gaactaagat
    34021 catgaagatt gagagtaaag aagatagagg acgaatgtat gagaacacac tatatttatt
    34081 tagaagataa aattatagat gaaattccgg caaaaagtcg agaacaagct agaaaattat
    34141 ttattgaaaa atacaaagag atcaatggag atagtgaagt tccaaaagtg gtcgtaacag
    34201 ttagaaaaag gcaaacaaaa aagagaagta cgtttcatgt cagccctgat atatataatc
    34261 ttatagagcg acatagaagt gaagataata tttctatctc tcaatatatt gctacagtta
    34321 ttgatgaatt gatttcagga aagtatgact atgcttttga ttttgaggat gaaaaggatt
    34381 acaaaagtgt tgctgtcttt caatctgatt ttgagaagct aaaaaactat gctggcagga
    34441 gaaatgttaa ttttgcaaga ctactagaag agttctactc cgaagagttg ggagtaggaa
    34501 atgaatacaa gagagaaact tatgcgaaat tgtctcataa gttatcccaa gcgcttaaag
    34561 aagtgacaga agttaaagcg gaactagatg ctaaacttga agaagtgaaa aaatatcaaa
    34621 cagagaggaa gaacaacatg aagaatcaag tggaatttga cgaacagaaa gaatttgaaa
    34681 aagcaagaaa acgctataac aaaattatga atgaacttag ctatgaacac ttaacagttc
    34741 atgaagaatt gagtgagggt acagaaaaat atacgatcgc agatatggtt aatgaagtgg
    34801 aaactctttt agcttctttc tttgaaaatg gtcacgtaaa cgatgaatgg cgaaaagaag
    34861 aacctaaaag ggttaacgct tatattgctc gattaaaaag gtttattgat aaatataagg
    34921 agaatagtga caaattttct aaagataaat aaggagagag tgtgattaca tttgccagaa
    34981 atcgaaggaa tattttcgcc aaaaataggt aaaaaacagt tagatttcag cagttttccg
    35041 agcgtaaata gagattataa tctaggtgat gaggtacaga tactaaatat tgatttcaaa
    35101 gaactagact tcgctgttgc tgtttccaac aaacccaagg cattggaacg agtgaaaaaa
    35161 atataccaag agaatgatca aaatatcaaa aatatgatca aaaagtatag acgagataat
    35221 tcaaaagttg aagacgtttt attcaacggt acggcaaaac atgatttgaa tgtttatatg
    35281 gcattaggag tggctttgta ctgtaattca attaatcaga cagatatttt ggttaatatc
    35341 gtgaggaata gctatcaaaa aatattaaaa ataagtagcg aaacaaaccc ttattatgca
    35401 atgaaatatc ttggggataa tttattaaat gataaaaaat tgatgcacaa cactgaagag
    35461 ctgttatcta atttggctgc gattaacttt ctattcaaaa caggttctga agattatttt
    35521 atagataacg tactaaaagg tgcttacgga acagcatttt atccgcttta caatatgaaa
    35581 cagcataaag ccgaacaaaa ggataacaaa cttgaaatta aaaagatgaa agaactatta
    35641 ggtataggat ttgtaaagcc caattcaaaa gtcactattg cttcgttagc aactactaac
    35701 aataatggga aaatagtaaa tgggtttgac gattcagata tagatatatt gtcaaaatca
    35761 tatttttctt tgtatggaga ttttgcagat ttgatgggta ttgatagtta cttagtcaat
    35821 aattttgaga tcaagggtag cgagctgaat gatattgtgt atttcgtttt aatctctcta
    35881 tatgcaattg atcagaatac cgagtaccga caaattgact atttgctagt tttttatagt
    35941 ttgttatatc agttcgtttt aactcggttg tttaaaaatg ctaaggaaga attgatcctg
    36001 aattctgatt atgaaatagc aaaacaaatt gcaagtatta gaaaagaaaa caaatctgaa
    36061 gtaatcaaat taagaaaaga attaagtatt gcgagtaaag aaaacggtcg gttagaatct
    36121 ttagtcaaat cggcaaaaaa agaagaggaa cttttgaagc aagagattaa agaattaaaa
    36181 ggaatcagaa aagaacttga acagctgagg tttgaaaata aagtattaaa gcaattgcag
    36241 gagcaagaac atagacaatc attaaatggt aaaactgaag agccttcact gtctgaaatg
    36301 atagcttatc taaaacataa aaacattctt ttagtgggag gacatgtaaa ttttcaaaat
    36361 aaattaactg aactattacc aaatattaaa atgtttgatg taagcgaaaa taatggaaag
    36421 atacttaaaa atttgaatac gtgtgatgcg atttttctat atacagatta cttgaatcat
    36481 ggtctatatt atcgtgttat gagtgaaatt tctaataaag ataagatatt ttatttagat
    36541 aatcatgtga atatgagctt aacaattaaa cgtatttatg atcttttata tgtttataaa
    36601 cattaatgag gtgttaaaat tgacaacaat aactatgaca aaaaaaatag aagtatatgt
    36661 tgatggatca caagaagaaa gggattcctt ttttgatttt ttttggaaaa atagtagaga
    36721 atatgtaaaa gcgttgaatc tggtatataa acagctaatg tttgaagagt tgataaaaga
    36781 tgcaattaaa gaaatggatc aaggttatgc tgagagagaa gaaagtattc aaaatcggat
    36841 tgaaaagtta gcatatactg atccaataga tcaaaaaaaa cttgataaag caaaagctga
    36901 attatctaaa ttgagaaatg aaaaaaataa agaagcgaga gaaatattaa cgcaagcgat
    36961 agggttgaag agtcaaacga gaacacgaga tgtagcaaaa aaattagact ttgactttgg
    37021 agattttgtt gattccgcaa atatgaaagc tagtaaagat tttggcaatg attttatcgg
    37081 aattgtgacc ggacaaagaa cgcctagaat atataaaaat agaagtaaat atggattatt
    37141 accttttaga ggtcgagata ttaaaatcca taaagatgat aagttttata tttatttacc
    37201 taaaggcttt aggtttaaag tgaatttagg tagcaagcca agaaaagcaa gagatgttgc
    37261 ttcagtttta caacacatta tggatggcga ttacaaatta aatcaaagta atcttatttt
    37321 tgatggaaga aaattatttt ttaatctaac aatttctttt gaaaaaagat ataatgaact
    37381 ggagttcaag gaaggtaatg aattgatcgt aaactttgca gatttgtgta gcggtgaatg
    37441 tttagttaat aataaatcgg taatgtcttt tggtgatagc caatatataa gaaacttcaa
    37501 aagtaaaatt ttagcaatga aatcaaaaga acaaagccga ggagtctttt ctaaaggcgg
    37561 tcatggtcga aaaagaaaat tagatcaaga tcgatgggaa gcaataaaga aaagagaaag
    37621 taattttgtt aaaacttata ataatcaatg ttctgcaaaa atcgttaaaa ctgctattcg
    37681 caataaagct caaattattc gtatcattga accagataag gcttatggcg aatgggctta
    37741 ctatcaattg aaagaacaac tagtaaataa aggaaaaaga tatgggatag aagtcagaag
    37801 ttagtaaagt aaacaatcgt tgatttggca acgaaatagt gagggaaaat ccactcactg
    37861 aagggtaaac tccgtcaagt tgtgtgacca gacggaagga cgagcgttgt tggggtttta
    37921 gaaccatata aaacagcatg tttctcaaat tgtgtttgtt tcatttatgt tataataaga
    37981 gttttagagc catataaaac agcatgtttc tcaaatgagt actttaaatt aattgatggc
    38041 gttcctgctt tagaaccata taa
//
LOCUS       DAZKCW010000026        37940 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000026 DAZKCW010000000
VERSION     DAZKCW010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.026"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            61..3339
                     /locus_tag="ACG84Z_001446"
     CDS             61..3339
                     /locus_tag="ACG84Z_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFP9162297.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3880..5787)
                     /locus_tag="ACG84Z_001447"
     CDS             complement(3880..5787)
                     /locus_tag="ACG84Z_001447"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFP9162298.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            5917..6792
                     /locus_tag="ACG84Z_001448"
     CDS             5917..6792
                     /locus_tag="ACG84Z_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFP9162299.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            6872..7846
                     /locus_tag="ACG84Z_001449"
     CDS             6872..7846
                     /locus_tag="ACG84Z_001449"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFP9162300.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            8026..9171
                     /locus_tag="ACG84Z_001450"
     CDS             8026..9171
                     /locus_tag="ACG84Z_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFP9162301.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            9308..9652
                     /locus_tag="ACG84Z_001451"
     CDS             9308..9652
                     /locus_tag="ACG84Z_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFP9162302.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            9923..11209
                     /gene="efmA"
                     /locus_tag="ACG84Z_001452"
     CDS             9923..11209
                     /gene="efmA"
                     /locus_tag="ACG84Z_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFP9162303.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11347..11946)
                     /locus_tag="ACG84Z_001453"
     CDS             complement(11347..11946)
                     /locus_tag="ACG84Z_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFP9162304.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12350..13471
                     /gene="mnmA"
                     /locus_tag="ACG84Z_001454"
     CDS             12350..13471
                     /gene="mnmA"
                     /locus_tag="ACG84Z_001454"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFP9162305.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            13717..15138
                     /gene="arcD"
                     /locus_tag="ACG84Z_001455"
     CDS             13717..15138
                     /gene="arcD"
                     /locus_tag="ACG84Z_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFP9162306.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            15152..16270
                     /locus_tag="ACG84Z_001456"
     CDS             15152..16270
                     /locus_tag="ACG84Z_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFP9162307.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(16330..17622)
                     /locus_tag="ACG84Z_001457"
     CDS             complement(16330..17622)
                     /locus_tag="ACG84Z_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFP9162308.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            17772..18332
                     /locus_tag="ACG84Z_001458"
     CDS             17772..18332
                     /locus_tag="ACG84Z_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9162309.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            18461..18838
                     /locus_tag="ACG84Z_001459"
     CDS             18461..18838
                     /locus_tag="ACG84Z_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFP9162310.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            18771..20843
                     /locus_tag="ACG84Z_001460"
     CDS             18771..20843
                     /locus_tag="ACG84Z_001460"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFP9162311.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(21054..22001)
                     /locus_tag="ACG84Z_001461"
     CDS             complement(21054..22001)
                     /locus_tag="ACG84Z_001461"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9162312.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            22247..22711
                     /locus_tag="ACG84Z_001462"
     CDS             22247..22711
                     /locus_tag="ACG84Z_001462"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFP9162313.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(22773..23816)
                     /locus_tag="ACG84Z_001463"
     CDS             complement(22773..23816)
                     /locus_tag="ACG84Z_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFP9162314.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(24193..25158)
                     /locus_tag="ACG84Z_001464"
     CDS             complement(24193..25158)
                     /locus_tag="ACG84Z_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFP9162315.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25392..26237
                     /locus_tag="ACG84Z_001465"
     CDS             25392..26237
                     /locus_tag="ACG84Z_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9162316.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            26428..27615
                     /locus_tag="ACG84Z_001466"
     CDS             26428..27615
                     /locus_tag="ACG84Z_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFP9162317.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            27621..27977
                     /locus_tag="ACG84Z_001467"
     CDS             27621..27977
                     /locus_tag="ACG84Z_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFP9162318.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            27979..28317
                     /locus_tag="ACG84Z_001468"
     CDS             27979..28317
                     /locus_tag="ACG84Z_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFP9162319.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    28393..28649
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            28712..29746
                     /locus_tag="ACG84Z_001469"
     CDS             28712..29746
                     /locus_tag="ACG84Z_001469"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFP9162320.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            29739..30425
                     /locus_tag="ACG84Z_001470"
     CDS             29739..30425
                     /locus_tag="ACG84Z_001470"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFP9162321.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            30449..31297
                     /locus_tag="ACG84Z_001471"
     CDS             30449..31297
                     /locus_tag="ACG84Z_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFP9162322.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            31494..32267
                     /gene="sufC"
                     /locus_tag="ACG84Z_001472"
     CDS             31494..32267
                     /gene="sufC"
                     /locus_tag="ACG84Z_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFP9162323.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            32280..33566
                     /gene="sufD"
                     /locus_tag="ACG84Z_001473"
     CDS             32280..33566
                     /gene="sufD"
                     /locus_tag="ACG84Z_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFP9162324.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            33563..34798
                     /locus_tag="ACG84Z_001474"
     CDS             33563..34798
                     /locus_tag="ACG84Z_001474"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFP9162325.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            34785..35255
                     /gene="sufU"
                     /locus_tag="ACG84Z_001475"
     CDS             34785..35255
                     /gene="sufU"
                     /locus_tag="ACG84Z_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFP9162326.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            35260..36651
                     /gene="sufB"
                     /locus_tag="ACG84Z_001476"
     CDS             35260..36651
                     /gene="sufB"
                     /locus_tag="ACG84Z_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFP9162327.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(36749..37891)
                     /locus_tag="ACG84Z_001477"
     CDS             complement(36749..37891)
                     /locus_tag="ACG84Z_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9162328.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
BASE COUNT        12332 a         6988 c         8071 g        10549 t
ORIGIN      
        1 aaaataaatt aggtaatact ttaagtaaac gctttctaat ttgttacggg aggaatacac
       61 ttgttaaaaa aacgtataaa atacagtgcg ctaatgatga atctccttat gctcagtacc
      121 ccggttttaa tttctgtcgt tgaagttgct gctaacgaac aacagtctgt gaacgaagaa
      181 aatgcacacg tgaacattga agggatgtca acaatggagg aaataccaag aactagtgaa
      241 gatatggata cggaagaagg aaatgatcct atgatgaaag aatcagaaaa tgaaaagaca
      301 aaaaagcaat ctgaagaagc aaatgaagag tggaaagggg ttgttttcgg agaaagcaca
      361 agtgctagta ggtatgccat tgaaccatta gaagacggcg tgcggctctc ttccacgaat
      421 aacggcggaa aattccagtc aagcggatca gatggaatga cctattatta tcaagcaatc
      481 cccaaagaca tcaactttag gatgcgggcg acgatcgaaa tagaatcttg gacctatacg
      541 aatgcccaag aaggatttgc tttaatggta agagacgcag taccaaaaaa tcatttgttt
      601 gggcaggcat tttattcaaa ttcatttgcc atactaggca gtcggatcga atatgtctgg
      661 gactcggata gacaagaagt ggtcaacacg agcggcagca aatatacgat gcgacttgga
      721 ttggggacac gggcaatcac aggaatatca tctgaagatc cgcaagctgc gccagctcct
      781 gggagtgtct cagtggaaac aacaccttta gagacttcag cagggttctt ggaaaaagaa
      841 acaggttctt ataatatatt cggaaacggt catgggaatc tgtttccggc cacgaactcg
      901 attactaaac tggacgtaga gatgaaaaaa acgaatactg gtttagaggc atattattac
      961 gatcctgaaa caggagaaga aatggcttct gacatcatgt atgactggga aaaattatac
     1021 gcttcagatg aatcggttat ttatgcagga tttgctgcag caaggaatat gacgatcaag
     1081 gtagaaggaa tcgaagttgc ttactcagat cctgcgacag atcctcctgg gcaagaaaga
     1141 cctactcgct tgattgatcc gatttacact gtgacctcta gtaatcattc aggaaaccaa
     1201 gatcatacta tgtcctttag agcaaatgct gacggattat tgacaattaa aaataaagca
     1261 acaggagagg tgcttaagaa cgcaaaaaac ttggctatca ctgcgaatcg ggaatttgat
     1321 tatcagacaa aactgatgga aggaacgaac gaatttactt tcagttttac gccagataaa
     1381 aactatccgc cagaagaata cgtagagatg actagttatg aaacaaaaga gattcttcat
     1441 acagtggact accgtaaacc taaatattcg acagtttatg taacaccaga agggtcagat
     1501 gcaggaaacg gaagcagaca aaatccatta tctctgacac aagcattgag atacgcatat
     1561 gctgggcaga caatcgtcat ggcgcctgga acttattcct tcgaaagagg attgacgatt
     1621 ccaaaaggcg ttaacgggac aagagaaaac ccgattcagt tgattgcaga gaaaaatcca
     1681 gaaaacaagc gtcctgtact tgattttaaa ggaactggaa atgggatgac actgttcagt
     1741 cactactggg gtttacgagg gtttgacatt acaaatagtg cagctatgca aaaaggatta
     1801 cagatttctg gaaatcataa tttgatcgaa gagattcatg cttatcggaa tggaaataca
     1861 ggaatccaaa tcagcggtag ctcaaatgat cctttcgaag catggcccgc gcataactta
     1921 gtcaagaact gtacatcttt tgaaaatgcc gatccaggat ttgaagatgc cgatggattt
     1981 gcggccaaac tgacaatagg agaaggaaat gtatttgacg gttgtatcgc gtatcataat
     2041 gcagatgacg gttgggacct ttttgctaaa aatgaaacag gttcgatcgg aaaagtaatc
     2101 atcaaaaact cagttgctta tcgaaacggc tgggtaccag gaattgaggg agaaggtaac
     2161 ggtaatggat tcaaaatggg cggttcttct ttaacgggcc ctcatgaatt gatcaatagt
     2221 ttgtctttcg aaaatcttgc gaaaggaatc gattccaata gcggaacaga tattatcgtc
     2281 aatagcagta caagttttaa taacggttca tataatgtgg ctctttatac ctcttcagca
     2341 ggaaacacag actaccatgc ttctggtatc ttatctttcc gaacagagaa tcttgagatg
     2401 agagagcaga tccgcccatt gaatcaaaac gaagatcaaa tctaccactc gttgaactac
     2461 tattggaatg aacgagagaa acaatcagaa aatactcttg gacataccat atcaaaagat
     2521 tggatcgagt ctctaaatac atgttcgaaa gaaggtcagc agcctgttac gcgctatgaa
     2581 aatggaagta tccatgttca tggactgatg cagattaaac cggggaatcg tcaaacagaa
     2641 aaggaaagag tggatggtct tccattatct gtaggtgcta tttttgacgg agaaacctca
     2701 ccgtcttcgg aatatccaga gtatgcaatc gtacaagaac caaatcagac aaaaccaaat
     2761 gaacaaaata atccgattat tatacaagaa gcaaatggtg tggcggagaa tgcagaagga
     2821 aatatcattg aactgaagcc ttttacagtt tttgtgtcaa ctttcacacc aaatcaagga
     2881 acgcctgtct ttgaagatat gcgttatttc ccagaaaaga tccaaatcgt tgaaacacag
     2941 tcaagtgctc aattttctaa tcataccgct attttttcag caccttcaaa aggagaatat
     3001 acgctagaag tcacttatcg ttcggaaata tttgatgggg aaaaatggtc tgctcataca
     3061 gaatctgtta cccagcaaaa agcgatcact gtgcgagaaa ctgccgatgt gcccccggga
     3121 aatgacaaac cagaaagaga aaatccagga aatgaatcac caaatggaaa accaaatgga
     3181 aaaccttctc atccggatag gacagcaaaa gaaagtgaaa aaaatggcac tcaaggactc
     3241 ccaaaaacgg gagaatttaa taacccgttg ctagcattag ctggaggaat tttgttaatc
     3301 ggtgtagttg tttatgtcat gaaacagcga aaaaaataag tggaatttct ccttttatga
     3361 tgtaaaacaa ttgactgagg aaagtaaaaa tagaaggaaa tgagaccaat agatgtctca
     3421 cttccttcta tctttttata gatgaggttc tccttgctgc ttttgattgg ctgttcttat
     3481 tacttgatgc aggacagctt tttcacaatc tctccactaa acggtgttca atcagctgac
     3541 cctcggtatt agctcaacaa acggcaaaat atgaggaact atttttccgt ttttttctct
     3601 aatactcagg tcaggacgct gatttcacaa cctctcgata aacggtgttc aaaagccagt
     3661 ttctcggtag taagtcaaat ttatgcaaaa atgtggaaag ccattttcac aaaatttttc
     3721 ttactacttg aaactaagca gctttttcac aacctctaat acatggtatt ccagaagtaa
     3781 cttcttcgaa aaataagccg aaatgtcaca aaaatttgag aagcgatttt cccaaattcc
     3841 ttcttatttc ttgaagctga ccacttctgg cacaacctct taccagattc gcactctttt
     3901 ttctggcgct agatacatag cgtcttgttc cgtgatacca aatgtttcat agaattcgtc
     3961 aaggtttttt ggttgcacgt ttgctcggag tttagcaggg gcatggacat cgatttgcag
     4021 taaaagttgt tggtattctt tttttgcttt tgtacgccaa atcgttgccc aattgacaaa
     4081 gaattcctcg atagaaagat ctgattccgt ttttgctgct tccaatgcac agcttagacc
     4141 gcctgcatca gcaatatttt ccgaaacggt taattttccg tttacttttc cgtcagcaaa
     4201 aggcagacca tcgaattctt cgatcattgc ttgtgctttg ttttgaaatt gtgtaagatc
     4261 ttcttctgtc caccagttgt tcaagttgcc atattcgtca aataaagcgc cgttattatc
     4321 aaatgcatgg gaaatctcat gagcgataac agctccgatt ccaccataat tagcagagct
     4381 tgattgttct agactgtaaa atggtgcttg aaggatcgct gccggaaaga cgatcacatt
     4441 ccgaaatgga tgataataag cattgaccgt gtcagcactc atttcccatt ctgaacgatc
     4501 cactggtttg ttccatttgc tgaaacgatc ttttaatgtg agtttgctga aaacaagagt
     4561 atttgaaagc aaagtaccac cctgatctgc aggtactgtt ttgaactggt cgaataatgc
     4621 tgggatctta tcggggtagc ctacttggat acctaagtta tttaatttta tgacggcttt
     4681 ttcttttgtt gcatccccaa gccagtcatt ttcttctaga cgttttttat aaacggcgat
     4741 catttttttc accatttgtt ctacgtcttt tttagcagct tcgccaaaat atttttttcc
     4801 gtagtaatcg ccaactactt gatcgaattg tccagaggca aggtaatacg ctgctttttt
     4861 ctgaggcatt gcttcgtctg ttccagacaa tacgcgagaa tagattccgc tgacttggcg
     4921 gaattcttct gatagataac cactaagaga acgtactgtt ttaatgatca tccagctttt
     4981 gaataacgga aaatgagctt ctgtcaggat gtcattcaaa tgatcgaagt acactggatc
     5041 agttacgatc actttatctg gagttgtccc aatcaaaccc gtgacaagtt ttttcaagtc
     5101 cagtttatct gtgtatttaa taaatgtatc aaaagattgc ggattataca ttttgctgta
     5161 atctgcgttt tcttctgcac tttttacatg aggagcaatc aatttatcaa attgcactgc
     5221 ttgttccgtg attgcttctg cctgactttt ttctttgccg gcaagctcta ataactgaac
     5281 agccatatca aagaaaacgc ctattagttg tgcaccgttg ggatggtctg atgcataata
     5341 cgtcttatct ggaaggaata aagaaggcgg ataagcaaag aaggcgttcg tttgcgcatt
     5401 cttcatatct gcatctacat ccagattaaa tggcaatggt aatgtatcca acagccattc
     5461 tggaaattgc ttattcaatt cgtcgaaaga ctgcaatgat tcaacttttt cgattatagg
     5521 ttgaagcggt tgagcatgca actcatttct tcggtcataa tcgtttgcca gttgataata
     5581 tgcaaggaaa tgtttcattt tttctgaaga cactttttct ggatgggcaa gcagatcgtc
     5641 tgtttctccc atcaaaagtt ggtcgatccc gtcaactaaa tcttggaaac cgcctgtagc
     5701 tggtttatct gcagggattt ttgctgtttt ttgccattct tcattgactg cttcatagaa
     5761 atcttgtttc aatcgttctt tgttcattca tcgatcgctc cttttttgtt tcgtgtgccc
     5821 attatcttac aaaatgaagg aattaacaaa tagaacataa aaaattgaaa attcgaacaa
     5881 tcaaactgat ttgttttttt caatccttca cttataatga aaaaaaggag gcgatcccaa
     5941 ctgaatcaag tagtggataa acctttatat ttcaaagtag ataaaaaaat taaaaaatta
     6001 gccagcactc agcagctgca gtcaagaaaa agtaaattgc tttttttagc tctggttttt
     6061 gaagatcaaa gttatgtgat tatcgatcaa tcaggacatc cggtagaata ttctccagca
     6121 aaatatactt atcaagaggg tctttcttgt aaaaaatgga agctgatcaa tgaagagcca
     6181 atcgagttat ctagatggat caacagaaaa gaagatattc ccgttttgat cgaagaaaaa
     6241 aggtcaggaa aggaactcgc aaattgctgg gtgggattgc cagaagaacg ttttttgagg
     6301 tataagaaat gggctacccc ctcaggctat ctttgtggta cttacgcggc agcagttctc
     6361 cttgcctatt atcaagacta tcgtaagggg tggatgcttc caaatgagat tcgcaagaaa
     6421 aatacggctg attcgttggt tttgacgaag gcattgcgta gccagatcca accactagga
     6481 cttcctacga ttccttttca ggttagtaca gggatttcta gttttttaaa gaagaatggc
     6541 aatcatgagc gtgcacgagc aactcttcta ggttcatggc agcgagctac aaaacgtata
     6601 cgtgaaggca aacctgtgat gattggtatt ttgaaagtac ttggcagtac atatggcaat
     6661 cattgggtga cagcgtacgc ttattttgaa actgaaacag gagaacgtta ttacaaagta
     6721 cacgacaact ggggcgatta tcataaagtc attcctgcca gttggagtaa cggaacagtt
     6781 tcacttcctt aagaatttgc tgaaattaac agaaaatctt ggaaaaatat gttaaactat
     6841 cgaagaatag agaagttttg gggaggacta catgagtaat aagtatcagg atgacacgtt
     6901 gaagattttt agtttgaatg gcaaccgtcc attagctgaa aaaatcgcga aagtgttcgg
     6961 aacagaatta ggtaaaagcg tcgtgaagca atttagtgat ggcgagattt ccatcaatat
     7021 cgaagaaagt attcgagggg atcatgtgta tatcgttcaa tcaacgaatg cacctgtcaa
     7081 tgattactat atggaactac tgatcatgat cgatgcaatg aagcgagcaa gtgcgaaaac
     7141 gatcaatgtc gtattgcctt actatgggta tgctaggcaa gaccgcacgg cgaaacctca
     7201 tgaaccgatc actgcgaaat tgatcgctaa cttgatcgaa gaagcagggg caactcgagt
     7261 actgacttta gatctgcaca cggttcaagt acaaggattc tttgatattc ctgtagataa
     7321 tttatttacg atgccgttgt ttgctcatta ttaccgtcaa ttaggtctga cgggagatga
     7381 catcgtagtt gtttcgccaa aaaacagcgg tgttcagcgt gcacgtagtc tttcagaata
     7441 tttgaacagc acattagcca tcgtagatca tgcagatgat gcttcaactg agggtggtta
     7501 tgtgatcggt gatgttcaag gaaagacatg tatcatggta gatgatatct tgaacacagg
     7561 agcaacgctt gcacgagcag caaatgtatt aaaagaaaac ggcgcaaaag aagtatatgc
     7621 ctgtgcgtca catggattat tgtccgatca tgcgaaaagt attttagaca atgcaccaat
     7681 caaagatatt tgtatcactg attctgtttt cacagaagaa aatcgtcatc cagaaaactt
     7741 aacaatcgtt acatgttcag aattaatggg tgaagcggtc aaacgcatcc atgaaaatac
     7801 accgatgagt ccgttattcc gtctggaaga aaaagaattc gaataaacaa aaaaaagagg
     7861 gaaagaagtt gtgacagaag tgagcagctt caaggagctg cgacaagact tttgtcacag
     7921 ctcctttttt ctatgcccat gaaacgtcct ctagacaaaa atgagctctt ctttggtttg
     7981 ttcgctattt tatgctagaa tgtgcctagc aataatttgg aagggatgaa tgaagtgaaa
     8041 actatttatc tggatcatgc ggcaactacc cccatgcatc cacaagtaat tgaagcgatg
     8101 acggcaatca tgcaagacac gtttggaaat ccttcaagca tacatggatt tggtcgccac
     8161 gcgcatgaaa aattggaaac agcaagacaa atcattgcag acagtctgca agcaaaacct
     8221 cacgagatca tctttaacag tgggggaaca gaaggggata atacagctat cttagaaaca
     8281 gcgttctcgc gtcaaaaaga aggcagacat ctaatcacta cagctatcga acatcctgct
     8341 gttcttaata ccatgaaata tttagagaca aaggggtttg acgttacata tctgcctgta
     8401 gatgaaaaag ggaatctgtc gatcgaagag gtcaaaaaag cgttacgaga agatacgatc
     8461 ttggtctctg tgatgtacgg gaacaatgaa atcggaaatt tgatgccaat caaagaaatc
     8521 ggtgaacttt tagcggatca tccagcttat ttccatacag atgcggtaca agcgtacgga
     8581 aaccaaacga tccatccaga agaattagga atcgatttat taagtatctc tgctcataaa
     8641 atcaatgggc caaaaggcgt cggtttctta tataaacgag acggagtaaa tatccctgca
     8701 ttgcttttag gcggggagca ggaagaaaag cggcgtgcag gtacagaaaa tttagcaggg
     8761 atctggggta tggcaaaagc agttgaactg ctgtcacctg aagaacgtga agcacgtaac
     8821 aacaaatata aaggattcca gcaattgatt cttgatacat tagaagcaaa cgaaatccct
     8881 tatcaagtaa atggtgattt aacgaataaa ctccctcatg tgttgaatct tcgcttaatt
     8941 ggcgaagcaa atgatttgct actgatgaag cttgatctta atggggtcgc tatttctact
     9001 ggttcagctt gtacagcagg aaatatcgag ccttcacacg tattagaagc aatgtatgga
     9061 gaagatacac cgatactaaa agaatccatc cgtatcagct ttggtttggg aaataccgaa
     9121 gacgacatcc agtatttcct tgatcaatta gttcgtgctg tcaaaaaata actagtgaag
     9181 tcattcttat atgaacagat gtctgagaga acgccttcat tttttaggga acttaactga
     9241 aaaacctagt aaaaatcagg ataaactttt ataataaaga gaaactaatt ttatcgaggt
     9301 gaaaatcatg gcatttgaaa caacagcaac ggtactgggc gcaccaatta gctatcgttt
     9361 gcatcctgat gcaaaaagat atacattgcg cgataatgga tttacagaaa caaacggagg
     9421 caattatcaa ttgatccgac cattagatgc cacgccgcaa agcaaagaag gattcaaatt
     9481 aaaaatcact gtatcaaaag atattcaaac attgaaaatg tcgatcacta cagcaaatgg
     9541 attgaaagca gtcaatattt tcaaagatcc aaaacagaaa atgagccaag ataaatttta
     9601 ttttctgatg gatgggatga ttagccgtgg gttattcgaa aaagtcgaat gatctgtgga
     9661 tataaaaaga caactagttt tgaaacggcc tattgttaga tgactaactt tgtaaggacg
     9721 acgcaaatta gttgtctttt ttatttttaa atttaacaca tgttgttatt tttaatattt
     9781 tgctgattta ttgtttctaa gtaaagaaat ttaaattgaa acgattgtta tttagggaaa
     9841 aaggtatttt ttgaaaaaag aatcccgtat aatgattgtt gtgcaaacgc tatacaaaat
     9901 gaaaaagaaa agagggatgt ttatggaaaa tgaacagtcg gtcgttttaa cgaattggaa
     9961 gagaaattat ttgttctttt tatcgggaca gtttttgtca ggaatcacta gtatggtcgt
    10021 ccaatatgcg atcatctggt atttgacaag agaaaccggt tcggcgacaa ttttgagttt
    10081 tgctacttta ctaggaatga ttcccatggt tttactaagc ccatttgtag gaccgctagt
    10141 ggatcgctgg gataaaaaag ctcttttgat tgtcacggat attattgtag cgattttcgc
    10201 gcttatttta gcagtagtcg gaacgatttc agaatccttc ccgatttggc tagtttttgt
    10261 gtctttgttt atgcgttcgg tcgcacaaac attccaaatg ccaacgatcc agtcgattat
    10321 gccgacaatc gttccatctt ctcacataac aaggacgaat ggacagttag gaatggtcca
    10381 atcagcgaat ttcatcattg cgccagctct aggtgcggct ttgttttcag tcgttcctgt
    10441 caattacctt attttattag atgtattggg ggcagttttt ggtgtcggct tattgatttt
    10501 tgtgaagatc ccaaaagttt ctcctgaaat attggaagtt ccgcttacta tttttaaaga
    10561 tgcaaaattt gggctgcagc aattgatgga taataaaggg ttatggtaca taacgatcaa
    10621 tggtgcattt gtgatgctgt tgttcatgcc agcaatcagt ctgtatccat tgatgacgct
    10681 agattacttt ggtggttccg ttggacaggc gggagcagtg gaagtagtct acgcagtcgg
    10741 aatgctctta ggcggtgcac tgatcagttt tataggaaca tggaaagacc gaatgaaacc
    10801 tattattata gcctacatca ttatgggcct gacgatcggt gcaagcggat tggttccaaa
    10861 cgatagtcaa gggttcttgt actttcttat cttgaatgca ggagcaggtt gtgcaacgcc
    10921 atatttcaat acactgctga tggcaatgat ccagcagagt tatgaatcga atgttttagg
    10981 tcgtgtctta gggaacttca actctttgat gaacctggca ggtccaattg gattattatt
    11041 tgcaggacca ttagctgatc gtttaggggt agaaaaaatg ttcttgtttt ccggaatcgg
    11101 gattttatta tgcggaatcg ttttattttt aacgtcagct gcccgaaatt atgataaaga
    11161 attacagaaa aaactggtaa aagaacacca tgagcaaaaa gacgaatagt atggaatgga
    11221 gttgtgacag aagtcttgtt acaactccat ttctgatcct aatgttcctg tggcaataag
    11281 cctactcaaa tgaaaaatat gagtaattat ctttatttgt ttaatacttg atatagggca
    11341 gttttttcac gacctatcgt acttcctctt tgcttcatag atttctttga tttgttgctc
    11401 agataacgga gtgccaaatg gtagtttttc ctttaagagt tctctttccg gtgcgtctac
    11461 gcctacattg acatcgttct cgataggtac gctgtaatga tggatatgtc catgaagatt
    11521 gcggatagtg tcgttaggcc cgagcaacat cggataatga gtcaagtaat attgttgatg
    11581 gtcgaattta acgatggcac ctacatcata aaaataaaat ttgggacttc cgtcagtaag
    11641 cctaggatca tttttttcta aataacggaa aaaagcgcga ctgtcatggt tccctttgat
    11701 caagtggatt gttccttgca gttgagtgac cagttccaaa atttctgcat ttgctttttc
    11761 atattgcgga tgcatagcaa ggtcgcctag atgataaaca tggtcggttt cttttattac
    11821 tgcattccag ctagtgatca actgttggtt catttcatcc acatttgcaa agagccgcgg
    11881 agcaaagtcg ttttttccta ataagcgttc atggaaaaag tgcatatcac tgataaagta
    11941 attcatgtat cttttgcctc ccttttttct tagagtaaac aaaatcactt atctgagcaa
    12001 ctcataacat ctaaaaagaa aaggttgtaa atgagacgtg cagctttaag cgataagaag
    12061 caattttgaa aaatagtttt tcacaattta taaaattatt ccttattgcc gaaaggctgg
    12121 ccctttttat gagtatgcca attttttata tcgaatgctc aaaagatgag tgattttttg
    12181 gttgactatc atgtttgtgt actgaatagg tccagtagaa cagtattttt acgacttgat
    12241 aattaaggga tgaaattttc agaaatatga cgtataatgt aaaatactga aaagttgcga
    12301 ccttcaactc gtagatgttt cagaatctaa ttgaaatgat ggtgatatca tgacagacaa
    12361 cagcaaaaca cgcgttgtcg tagggatgag cggcggtgtc gactcatctg taacagcact
    12421 tttgttaaag gaacaaggat acgacgtgat cggaatattc atgaaaaatt gggatgacac
    12481 ggacgaaaac ggtgtatgca cggccacgga agattataag gatgtagcga aagtagctgc
    12541 tcaaatcggg attccttatt actctgtgaa ttttgaaaaa gaatattggg atcgtgtatt
    12601 tgaatatttc ctagccgaat accgcgcagg acgtacacct aacccagacg tgatgtgcaa
    12661 caaagaaatc aaattcaaag cattcttgga ttatgcaatg gatcttggcg ccgattatgt
    12721 agctactgga cattatgcgc aagtcactcg cgatgaaaac ggcgtggtcc acatgcttcg
    12781 tggagtagac aataataaag atcaaactta cttccttagc caattatcac aagaacagct
    12841 ttcaaaaacg atgttccctc taggcggcat ggaaaaatca gaagtacggg caattgctga
    12901 acgcgcaggc cttgcgactg ctaagaaaaa agattcaacg ggaatctgct ttattggtga
    12961 aaagaacttc aaacaatttt tgagcaacta tctgccagca aaaaaaggaa atatggtcac
    13021 tcttgatggt gaagtcaaag gacaacatgc tggcttgatg tattatacga ttggtcaacg
    13081 tcaaggacta gggatcggtg gcggaggaga ttcgcaagaa ccctggtttg ttgtaggaaa
    13141 agatctagcg acaaacacat tatatgtggg gcaagggttc catcatcctg cattgtatgc
    13201 cacaagcttg gatgcaagtg aaatccactt tacgacgaat gaaccaatgc caaaagaatt
    13261 caagtgtaca gcgaaattcc gttatcgtca gcaagacgtt cctgtgacag ttcgcttatt
    13321 ggatgataat cgtgcagaag tcgtattcga cgaacctgta cgtgcaatca ctcctggaca
    13381 agcagttgta ttttatgatg gaatggaatg tctgggtggt ggtttgatcg accacgcata
    13441 tcaagaaaca aaagttttac aatacgttta agcgatatta aatgaatcaa aacagctatg
    13501 gctaacaaaa gaaacacctt ttcttttgga tagcatagct gtttttttgc aataaaatta
    13561 atttttattc attttatact tgaaatactt gtgtaaaaag ttcataatat ccaataatat
    13621 gaataaagtt gctttttgtt aagcaagagc agttgcaaaa tagaagggaa tcttttgcaa
    13681 gtgatttgtt caattttata agtgagggtg atggaaatgg aaaagaaatc gacgggtatt
    13741 agcaaatggg gactggttgc tctggttgtc agttcgtcaa tcggaagcgg tgtgtttggg
    13801 atcacaagtg atctggctag ttctgcagct ccagggccag cgatcctttc atggataatc
    13861 gttgggattg gtattttagc tttggtatta tcgctgaatc atttaggaga aaagcgtcca
    13921 gatctagatg gtggtatttt cggttacgcg gaagcttcat ttggtaaatt aggtggcttc
    13981 atcagtggtt ggggttactg gttgtctgcg tggctgggaa atgttgcttt tgcaacgatg
    14041 ctgatgagcg ccatgggaga atttttcccg atattcaaag gtggacaaaa tgttccttct
    14101 attttatttg caagtatttt tatttggggt ctgactttat tagtaaacaa tggagttgaa
    14161 ggagcgagcg tcatcaatac aatcgtgacg atctgtaaat tagtgccatt attcctattt
    14221 ttaatatttg tatttatcgc atttaaagtg aatatattca ctgctgattt ttggggtaac
    14281 gtatctgata atctagtgaa tggaacaggg cagcaaggaa cgatctggtt gcagattaaa
    14341 ggttgtttga tggttatgat gtgggtcttt gtagggatcg aaggcgcaag tgttttagcc
    14401 aaccgcgcga agaaacgttc agaagcccag caagcatcga tcattggtct gctttgttta
    14461 ttgtttatct atatccttgc ttcgatcttg ccatacggcg tcttatctca agaagagtta
    14521 gcaactattt cacaacctgc tatggcaaat attttaaaag gaatcgtggg aaattgggga
    14581 gcagcgctga tcaatatcgg cttgattatt tcgatcattg gttcttggtt gtcttggacg
    14641 atgctcccag cagaaacaac gatgttgatg gctcgagacg gtctgttgcc gaaaggttgg
    14701 ggaaaaacga ataaaaaaaa tgccccaact tattcgttag ttgttactgc aatcttgact
    14761 aatctattct tattgacttt cttagttact gattatgcct atcaatttgc ctattcttta
    14821 tgtacagcgg caattttgat ttgttatcta cttgtcggga tctatcaagt ccagttttct
    14881 ttaaaagaag gaatcaaaaa acaagtagtg atcggtggga ttgctgtagt ttttgaattg
    14941 atgggcatca ttttagcagg attttcttat gtccttttat gtagtattgc ctatcttcct
    15001 ggtttttgct tctactggat cgcttgtcgt gaaaccaaac atcaaattac gggaaaagaa
    15061 aaagtaatga ttgggctgat ttgtgtggcc gcactgcttt caatcgggtt gcttgctgta
    15121 ggctggatca agatataagg gggaaagaaa catgaaaatc gcaaatttcg gtgtagaaga
    15181 atggctaaat aaatgggaaa agaaagcggt atatgatatt gcacaaagct cgatcgaagc
    15241 attgacatta gacgaactcg ttggcttaga tgggactagc gtaagtaaat ttttcgaaaa
    15301 acgcaaaaac gaaccattgg actatggctg gatcgaagga tcagatgttt tcaaacaaga
    15361 agtcgcttct ctttatcaaa ccgtcgatcc ggaaaacatc ttacaaacga atggagcgac
    15421 tggtgctaat cttttagctc tatacgcgtt agtggaagca ggagaccatg ttgtttcgat
    15481 gcttcctact tatcagcaat tatatgacat ccccaaatct ttaggtgccg ctgttgactt
    15541 tgttcatttg aaggaagaag aagattggca gtttgattta gaacagctag aagccttagt
    15601 caaacctgaa acaaaaatca tctgtttgaa tagtgcaaac aatcctacag gcacattgct
    15661 agatcggaaa actttagaaa aaatcgcaga aattgctcgt acagtagatg catatgtatt
    15721 gatagatgaa gtatatgcgc ctttaacgga taaaggtgaa ttcttgtcga tcgtagatgt
    15781 ctatgaaaaa ggtatagcaa ccaattccct atccaaaacc tactccattc caggtattcg
    15841 tattggctgg acagctactg gacctgagtt ggcagaagtt tttcgaaagt atcgagacta
    15901 cacgatgatt tgcggcggag tcctgtcaga tgatcttgct gtacatgcat tgaagaataa
    15961 agaaaaaata ttggcgcgaa acaaaaagat cattacagag aaccttgtga ttttaaaaca
    16021 atgggtagcc aatgaaccga aagttgaact tgtcgctccc aattacgtct ctacttcttt
    16081 cattaaatta gccatcgaag aagatgacca gacattttgt atcaatttat tagaagaaac
    16141 aggagtacta ttagtaccag gaagtgcctt tgatttaccg aagcatgccc gactaggtta
    16201 ctgttgtaaa aaagaaacct tggaaaaggg attattcctc ttatctgagt tcttgaaaaa
    16261 acaggcctaa acaaaaacac tgcaaggaca gtctgtgaca actgttcaag cagtgttttt
    16321 catttacgct tattgtctat gagaaggaga gtgccctgaa gctatggaga ctcctgaagc
    16381 tttttcttct gcagtttctt gctgatggat ctcttgtgta ttgtgtcgta caagcaagaa
    16441 gttgaccaaa acaagaagag aagtcgaaag aaagacgccg cgataaccaa atgcactgga
    16501 aacactggag ccgatcatag gccctactac gttaccagtt gcttggaaag attggttata
    16561 actgaagatc cgtccagcag cttgatgagg cgaatatttt gtgatcaatg cttggacagc
    16621 agggagcaga caagcatcag agataccaat caaaaaacgt aaggcagcta attgccaaac
    16681 attcgtgacg aatgccattg ggatataaac cagaatcgca aaacccaaac caatcgcaag
    16741 tattctttca ctcccaatct tgtcacctaa gcgaccaaat cttggagcgg ctatcaaagt
    16801 ggcaatccca ggtatcgaag caatgattcc gctgatcaac gtaacattcc catgtccatg
    16861 cagcaattgg cgaatgtaca gactgatgat tggactaatg gaattgttgg atgcttggat
    16921 gatcatcgtt gtgacgaaca taccgatgac gacgtgtgga tatttcaagt ctttgaaaat
    16981 ctgtttggca gaaaccatgt tttctttttt cactgggaca aatttttcat ggacgaaaaa
    17041 cagactcaac aagaagacga aaaataagat gatccctgta atgaaaaagg tagggcgata
    17101 gccaaacgct gaagcagaga tcccgccaag aagcggtcca agtaatgttc ctgtaacaga
    17161 accagttgct aaggttccaa gaacttgacc acttttttct tttggcgtcc cagttgcgac
    17221 aagggcagtg gcattactga tataaccaga aaaaatccct tgaagcagac gcaatgcgac
    17281 taattgatac acactagtca cgcaacccat caaagaaatg acgattgcca ttcctaatga
    17341 agcacgcaac agcatcaatt ttcttccttt ttggtcggct aattttcccc accaaggaga
    17401 gataagcgta gtcaccaaga aagtagatga aaaagtcaat ccgctccaaa agttcaattg
    17461 tgacgtacta taattaccta acgtatctat gtaaagtgac ataaaaggca tgactaaact
    17521 aaatccgata ccagccataa atgttccaaa ccataagaca aacaagtttt gttcccaagt
    17581 ttctcttttc ctaaataatt tttcctttat tcttgcagcc aattagactc cttctttctg
    17641 aaaattttca tctacagctc tttattataa actacaatat gtagtttatc aatgaaagtc
    17701 tcttttttct ctttcttttt cgtggtaaac tgaaagagtg aaggatttat tttatgagag
    17761 gaaacatgga aatgaaaaaa agaaatctgt ctcaagagaa aatcatcgac tgctttcgag
    17821 aactagcaga agagatggat gttcagcaaa taacctttca gcatttagcc aaacgcttgg
    17881 atatcaaggc tccctcgctg tataaccatt tcaaaaatat tcgtgatgtc aaaacagcgc
    17941 taacagcgaa acttctgcag gaacttaatg accagctgcg acgggctctt gtgggaaaaa
    18001 gtggtcagga agcactgcag atctatgcag aaacttatcg atcctttgct ttttcaaatc
    18061 aagcagtgta tgagttactg atcagtgtac cgcataccaa tgaagctgtt ttattagatg
    18121 gaatccatga aacgaatcag atcattttgc agatatttga ggcttttcaa ttaacgaaag
    18181 aagaaaaagt tcatcgaagc agggaacttc gtagtatgat ccacggttat ctttccttac
    18241 gttttttagg atactttaca aaagaaccaa caatcgatcc agaagacagc tatttttgga
    18301 tgatcaataa ctttatcgct actttgcctt aaacaatcag attcatttgt aacaatttta
    18361 agatgttcat taaatgaccc ttttataaga gaaaattctt gcaactttct tgaaaagtga
    18421 ctaagatgag tctagaaaag ctgaaagaag gagcacgagt atgtatcaag taattaccat
    18481 gttcggggac aatgagcctt ggtggttttt tgaagactgg gaagaagata ttgaagaaga
    18541 agaaacattc gagtctttcg aagaagcacg acaagcgtac gaaaaacaat ggaacgaaat
    18601 ccatcaaaat tatgaatata tcaatgcaaa aagtaacttt ctcagcgcct tttggaatga
    18661 cggagatgag cgctggtgtg aagagtgtga cgatgattta cagcaataca agggacttgc
    18721 gttgttgaaa aatcatcagc ccatcacagt agaaagcaga aaggaatttt atgaaacaac
    18781 taattctagc ggaaaaacca agcgttgcga aagacctaag caaggtgctt ggtgctaatc
    18841 aaaagcacaa aaattattat gaaggaccca aggtgatcgt tacttgggcc cttggtcatt
    18901 tattaggatt gaaaatgccg gaagatctga ataaggaatg gcagagctgg caaatggaca
    18961 cgttgccaat gatccctaaa aaactaggaa tcaaaccact tcctaaaaca ggacatcaat
    19021 taaaagcaat caagcagctg gctcagcgaa aagatgtctc agaagcagtc attgcgacag
    19081 atgccggaag agaaggggaa cttgttgctc gctggatctt agagtatgtg catttcaata
    19141 aaccagtgaa gcggttatgg atctcttctc aaacagataa agcaatcaaa actggattca
    19201 agcaactaag acctgcgaaa gaatatgatg cattgtatga atctgctctt gcccgggcaa
    19261 aagcggactg gctggtagga ttgaatgtga ccagagcctt aactgtgaag tacgcggata
    19321 atttatcagc aggccgtgtg cagacaccga cactagcatt agtgagagac caagaaaaga
    19381 aaatcgagca gttccgtcca caaacgtatt tcacgatcac gttgcaagct ggaaaagaac
    19441 aagccaaaat gcttcaaaaa aatcaatttg ctttaaaaac acaagaagaa gcacaaaaac
    19501 ttgttcaatt gatcagtaca agcaaaggaa ctgtcacaga agtccaagaa aaattaaaaa
    19561 cggaatctgc gccattgcct tatgatttaa cagagatcca aagagaagcc aatcaacgct
    19621 atggctattc tgcaaagaaa acattaagtc ttgtacaaag tttgtatgag acccataaga
    19681 tcgttactta tccgcgtaca gacagcaaat atctgacaaa tgacatgaaa agtacgatga
    19741 aagaacgatt gcaagcagtc agcgactttg ctcctgaggt caagcagtat ttgaaaaacg
    19801 gagccatcgt ccaacagaca aaagtattcc aagacagtaa agtgaccgat caccatgcac
    19861 ttttgccaac tgaaaacaga gcacgttatg aaaaattaag taatgaagag cgaaaaatct
    19921 atcaaatgat tgtctctcgt tttttaggac tgtttgctca accccataaa gtcagccaaa
    19981 caaaagttac ggttgaattt ggtaaagaac gattcatttt tcggcaaaat cgtgtcgtcc
    20041 aagcaggatg gaaaggcgaa actgaaactg agacggaaac agtcaaatgg gaaaaaggaa
    20101 tgagaatcaa tcccgatttc gccatcaaaa aagaactatc tgcaccgcct aaaccattgt
    20161 cagaagcaag cttgcttggt caaatggaaa aatacagtct gggaacccca gctacgcgtg
    20221 cagagattat cgagaaacta atcaaatctg aactgatgga acgtacccct caaggactgc
    20281 aagtatctcc taaaggtaag caattattag tattggtaaa tccctcttta gtaacaccag
    20341 atttgacaga aagctgggaa aaagaccttg aagctattgc tgcaggaaag aaacaagcag
    20401 gaaccttctt gaatggaatc gaaaaagaaa caaaacgctt ggtgaatgag atcaaatcaa
    20461 gcaaacaaga atatcaagat ttctcgatta cccaaaagaa atgcccagaa tgtggggcca
    20521 atctgcgcga gaaaaacaca cgtgacggca aaatctatgt ctgcaccaat tcagattgca
    20581 actaccgcag aagaaaagat ccaaaagtct ctaatcatcg atgcccgcaa tgtcaccgga
    20641 aaatggaaat catcgaaggt aaaaacggtg cttatttccg ttgtaaatac gatggaacga
    20701 cagaaaaatt gcttgataaa aaagagcaga agaagaaaat gaccaaacat gaagaacgac
    20761 gcttgctgaa aaaatatgca caagcagaag aaccagaaga aagcccatta gcagcagcac
    20821 taaaagcagc aatgaagaag taataagata tgaaagaggt tgtgatagaa gtggtcagct
    20881 tcaagaaata agaaggaatt tacgaaaatt gcttctcaaa tttttgtgaa atttcggctt
    20941 atttccgaag aagctacttc tggaacacca tttattcgga aaaaaggact gtgacaagac
    21001 ttttgtcaca gtcctttttc atttaaaaaa atgtttactt catttgacgt atattattgg
    21061 tgaggcttca attcatttgg cttcactttt tctgtttctc ttatgatata aacaggacgc
    21121 tgtttcgttt ctaagaagat tttcccaata tatttcccga tgattccaag acataacaat
    21181 tggattccac caatgaacag gaagatcgag accatggaag gccatcctga tgtaggatca
    21241 ccaaacaaca atgcccgcaa aataatgaac aaaattgcaa taccagaacc gacacaagac
    21301 aaagcgccga taaatgaagc aatcgttaac ggtgcatccg agaagttcac gataccatca
    21361 atcgagtagt tgaataattt ccagaaggac caagatgttt cgccagccac acgttcgcgg
    21421 ttttcataag aaatatattc tgttttaaat ccgacccagc taaataatcc ttttgaaaat
    21481 cggttgtatt ctgttaattc taggacggca tccaccattt gacgagtcat caagcggaaa
    21541 tcacgagcgc catcgaccat ttctgtatcg ctgattttat tgatcaactg gtagaatttt
    21601 ttcgcaaaga aactgcgtat cgcaggctcg ccttcacgag tcgaacgccg ggtgccgaca
    21661 caatcgatat cagaagtagt gatccggttg atcatctcag gaagcagttc gggcggatct
    21721 tgcagatcaa catccatcac ggtcactaaa tctcctgtag aagcttgcaa tccagcgtac
    21781 agagccgctt ctttcccaaa atttctggaa aatgagacaa agcggacata aggataagct
    21841 gaggctagct tcttgattgc tgctaacgta ccgtcttttg atccgtcgtc aataaacaaa
    21901 tattcgaact catgggcacc tttgaatttt tcaacctcat caaaaaaaag aggaacagtt
    21961 ttttcttcat taaaacatgg gacaacaatt gatactttca tcgtttctat cctttcaatc
    22021 gtatgtttat atatggttta cattcaaaat ttaataaacc ttaaataaca cctttaaaat
    22081 ttgattttac gtaaaagaac aggtattctt tttgtaaact aacgtattta gtttaccatg
    22141 tttcctcggt ttatcaaact tttaagaaca atttttatta gttggcaagt agttttggat
    22201 agagaaaaag gaggaagttc cagtctattg actaggagca aacaaaatga aaatacacac
    22261 acctatcggc tttttatggt tagatgcaga tgaatccgga ttgactgctg tatcttttca
    22321 gccaatttca gaaagcgaat cagcgaatca gcgaatttta acgcgcacac aagaacagtt
    22381 tgaagaatat tttgcgggaa aaagaaaaga atttgatgtt cctttatcta taaagagagg
    22441 tacgcctttt cagcaaaatg tctggaaagc tttgtcgacc attccttatg gagaaatccg
    22501 aacgtataaa gaagtagccg ttgctgttga tagtccgaaa gctgtgcgag cgattgggca
    22561 ggcaaatcga accaatccat tgccaatcgt tattccttgt catcgagtga tcgggcaaaa
    22621 tggaaaactg acaggatata tgggaaacgc aatagatggg gttgaaatca aacgccaatt
    22681 gttgttgtta gaaggatatc tgcaaaatta aaaacagttg tgattcggac attgttccat
    22741 gcgagaatca caactgtttt ttcatgttca ttctaaactt tgatcagcca aataaatagt
    22801 aaagccatca ctgtttggag aagcccgaca gctaatccat aagataagaa gcgtgtacct
    22861 tctttcatga attttgcaaa gtctaaacgc agaccaattg ccgctaaagc agtgatctca
    22921 aaccagctgc tgataaaatg tgccgattgg tcaataacta caggtaaaga aaacaagctg
    22981 ttgaccaaac aaaagatcac aaaccctaat acataccaag gaagcggtaa ttttcgtttt
    23041 ttctgcgtat cagttggcgt ttcaaacaga gctggttgtt tcttgtgcat gaatttttca
    23101 aacagataga caacaacaac gagcatcata atacgtagaa tcttaaatag catggcgaat
    23161 tcgacaacag aattgtcaag taagcttgcc ccagcgacta cttgaccaac agattggagt
    23221 gtaccaccca aaagtgcact tttttcaatg agatttccac caaacaactg taatccaaga
    23281 aaagggagag tcaacatcat cacagtaccc agtagattga ctagtgtgat gatctgtcct
    23341 ttttcttcct ctttcgcatg gatggaaggg gcgattgaag caatagcaga agaaccacaa
    23401 acagcgtttc ctccagccat catcaaagaa gaagtatcgc tgaattgcag ttttttacca
    23461 atcaagtaag caccgatgat agtgactgac atttgcagta acacaaaaac aattcctttt
    23521 acaccaattt gagcaatcgt ttgagctgtg acagttgcac ctagtaaaaa aacagagaat
    23581 tctaatagtt tgctttcagc aaattttgtg ccgattgcta gaacaggctg tttaaaaaaa
    23641 gtatttccta ataaaatacc caataaaata gcaatagtcg ctccacctaa ctgtggcaga
    23701 taaatagcaa gaagcctgct gaaggcagcg atggcaaaag aaagcagtaa accgggtaag
    23761 atttcgcgga ccgctgaatc ctttacagat tttattggat gtgacaatga tttcatttga
    23821 tcggttcctt tcgtcaataa atactaaaag catactcgaa catagtagca ctaaaccagt
    23881 attttgacaa aagaacaaga ggtcgtgaca aaagtcttgt acgacctctt gtttcgaata
    23941 aacggtgttc cagaagtagc ttctacggaa ataagccgaa atttcacaaa aatttgagaa
    24001 gcaattttcg taaattcctt cttatttctt gaagctgacc acttctttta cgacctcttg
    24061 gtaaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccagtac aaaaacatga
    24121 acagctgttt ttgtttggcc gttcttatta cttgatgcag aacagctttt tcacaaccta
    24181 ttgaatcgat tattaagcga tttttttaga aacaaatttt ccatgtttgc tatgttcttt
    24241 aattaagaaa cgtacgtaat gagcaagaac gtagaagaca actacacttg caaacagaca
    24301 ttccgcaact tttaagaaat ccaatacgct actatagata cctaaactgt tgaagtaatg
    24361 aacagtagta aatatagctg ttgcagagat aacaagcggg aatgtaaagg ctgcatagct
    24421 tggataaaaa cgaagcttga acaaacgtgg aagcatagac agcacaacga aatacaatac
    24481 ttgagataaa gcgaacaatg ctacgacaag ataaaaatta ggttcagcaa agtttttaag
    24541 ataacctgtt aggcaaagag aaccaggtgc tgcaacgatc gtaatcagcg gacgtgtcgg
    24601 atgagccata tttcttacga aaaagacacg tttgatgatg atcggcaata agaacgcata
    24661 gcagatcaat gaaatccaaa agaaaatttt tccaataagt gggaagaagt tcccggcagt
    24721 tacagtgatg accccaaatc caacgtaaat gataaaccag cttggataaa ttgcttcaat
    24781 tgaaagatca gctttgataa catggtgata attgaaataa aagacaagga tcacttggaa
    24841 gataacagcg cacagccaaa tgaatttgac aattggtgca atactttcat atgaaacaaa
    24901 ataagtacaa ataaccatga gtgacatcgt aaaagttggt gaaacggagg cgatgattgg
    24961 atcatgcaac gtttgtttcg tgtgttcgaa taagataaac aatttaacaa aaatgaatat
    25021 cataagaatc atagagatac cgccagttag attgcctaaa gcaacatggt gatagtcttt
    25081 aaacagattt ccaagggaag ctaacccaag gatcaacccg cagatcggga tcggaataat
    25141 tttcaaaaag ttcttcatat ataatattct cctttttatt taatagattt tagtaccaag
    25201 atgaacgaat acattgtaaa atgaatagga atgtatgatt acgagcaagc agacagctga
    25261 ttgtcttcat ctaagttact agttggatca gcaactgttt tgttgtacat ttctattata
    25321 gatggttttt tgtatattta aatcaaatag tttttatagt aattatcata aaaagttatg
    25381 gaagtggtgc catgtttaag ttattaacga cttttcgagc agtatatgaa acaagaaatt
    25441 tttccagagc agcagaagta ctgtttttat ctcaaccagc agtctcgaat caaatcaaac
    25501 agttggagcg ggaattgaat atcgatcttt ttcaacgtaa cggaagaaaa gagatgcttc
    25561 caactaagca agccgactta ttatatgaac ggacactggt tttgttagaa gaatgggaag
    25621 aaactcagca aaaattgctc aatgaacaaa atgaagaaga agtatgtcgg atcgttgctt
    25681 cccacacctt tgctgtctat cttttgcctc agttgatgaa acatctgatc aaaaggtttc
    25741 ctaaagtgca ttttgagatc gaaatcacga attctcatga atcattagaa caagtagcga
    25801 aacatgaatc cgattttggt tttatcgaaa agccattaga gacttccggc gtacaaagat
    25861 actctttgat ggaagaccag ctagtcatcg ctggggaccc aaaaagcaaa ttgtggcttg
    25921 taagagaagc aaactctggt gtttttcatt acacgcagcg ttattttgaa gagatgaata
    25981 tccaagataa gaagatgatc gtgaaaagta acgatgtaat tgttgcgttg ctgaaggaag
    26041 gaatcggtcg ctcgattttg tctaagcgct ctgttccaga aaatgtgcca atgactccgt
    26101 tgaatttcca tcgatatttt tatttcatcc aacgaaccaa tctggtttct gatcagctgc
    26161 tagagattgc cgaagagatc cttcgataca atgaaagcac agaaacttct cacagcgagg
    26221 agaatctcag ctggtagata attgcatgta tcaaaaaaag ttctatgata cactaaagat
    26281 aagcagtagg cttttgtact gcatttgctc aagcaactgc acaaacggaa agttaatttt
    26341 tcccaaatgt ctatggaaag actttccatt atctaactgg accgctataa taatcagcag
    26401 tatggttttt aagaaaaggg atgaaacatg gaaaaaaaat taaaagcttc gaacgataat
    26461 cgtattgatt atggcgtgat tttaccagtc tttctgttat gtttgattgg tctgctctca
    26521 ttatatgtag cacttagcca tgatccgaac aatccagcag tcttgaaagg cgtagggatg
    26581 caagttgtct ggtatttagt tggagcggca gcaatcgttg tcatcatgca tttgaattcc
    26641 aaatggatct ggaaactgac tccttacctt tatggtttgg ggttagtggt aatgggactc
    26701 ttgctcaaat tctatgatca gaatttagct gcttcaacag ggtctaaaaa ctggtttcga
    26761 ttcggtgcgt ttactttcca gccagcagag ttgatgaaga ttgcgtacat cttgatgatg
    26821 gcactgatcg taactaaaca taatacgcaa gtaaaagaac ggacgatgaa atcggacttt
    26881 tggctgattg ggaagctctt gatcgtgaca ataccggttt tagcattgat catggcccaa
    26941 gatgactttg gaacgatgct tgtctttctt gcgatctttg gcgggatttt cctgatgtct
    27001 ggaatctctt ggcgcatcat cgcacctgta gtaatcttgg cagtagtcgt tggagcagga
    27061 acgatcttct tggttacgac tgaaggcgga agagacttgc tttataaagt tggattcaaa
    27121 tcttatcagt ttgcacgtat tgattcatgg ctggaccctt tccatgatac gtcaggaatg
    27181 agttatcagc cggcccaagg acttttggca attggtaccg gtggcttgtt tggtaaagga
    27241 ttcaacgtaa gcaatatcta tgtgcctgtt cgtgagtccg atatgatttt taccgttatc
    27301 ggtgaaaact tcggctttat cggtggtgca ttcgtcattt tcttgtattt tattttaatc
    27361 tatcgtatga ttcgggtgtg tttcgatacg aataatgaat tttacgccta tatcgcaagc
    27421 ggtttgatca tgatgctgct gttccatgtc tttgagaata ttggagcaaa tatcggatta
    27481 cttcctttaa cagggatccc attgcctttc attagtcagg gaggatcctc gattttaggg
    27541 aacatgatcg gtatcgggtt gatattatcg atgagatacc aaaatgaagc acctgcaaga
    27601 tcttcaagga ggtaagaaaa ttgtacacct tttactggta cccgaaatgt tcaacatgca
    27661 aaaaagccaa agcgtggtta gaccagcatg gcgttagtta tcaaaccgtt gatatgatca
    27721 aagaagtacc gaaggcctca acgattgaga cttggctaga aacgagtcaa gtaccaatcc
    27781 gtcgcctgtt caacacaagc gggatgaaat atcgggaact tggactgaaa gatcaagtag
    27841 gcgagtttac ggcttcaaaa gcgagccaag tcttatcgac agatggtatg ctgatcaagc
    27901 gaccactgat cttacgagag gaccagcttg ttgcaattgg attcaatgaa aaaatttatg
    27961 aaggagaact gatataaaat ggcaggcaag catttgaaga aaaaggacaa cctttggatc
    28021 ttatttaatg gaaaagaata ctgtgttggt ttgacaaatg aagcgcaaga agaacttgga
    28081 gacatcacgt ttgccaatct gccaaaagca ggacaatcgc taaaaaaaga tgaacctctg
    28141 atcgaagttg aagcggaaaa agcggtcaat gaatttgcca gcccgctaac gggtacagtt
    28201 tcttctgtta atgataaaat cggtgaagat atcaatatct tgaatgattc agatgaaatg
    28261 aatgcgtgga tcttaagttt caaagatgtt gatccaaaag aatttgacga attataaaat
    28321 cagaaaatca cttgaaaaaa gttgacactg attcttccag ttgctataat cataagcaat
    28381 cctatatgaa acgagaaagc tttgaaaaga agagtacatg tcacggacgt ttgaagagag
    28441 ccctgtttgc tgaaaatggg taacgaaaat gagatggaag atggtcttag agcagagtaa
    28501 gcgagcgtaa gcaaacttac tacgggagtg cccgttacag cgcgacagta tacggaaaga
    28561 agctaagtcc aagtactgga agaggctgtt attgcgaagt aacggtaaat caaggtggta
    28621 acacggaagt tcaagctttc gtccttttgc ttaaggcaag agggcgaagg cttttttgtt
    28681 tgaaaaatta taagagaaag atgtgaatgg catgtcatta atccaactaa cgaatgtcaa
    28741 aaagacattc aatgggaaaa acggaaacat ccaagccgtc aatgacgttt cactaaacgt
    28801 tgaaaaaggg gatatttatg gaatcgtcgg ctattctggc gcaggaaaaa gtacattagt
    28861 ccgtctcctg aatggacttg agcttcccac gagcggcgaa gtgatcgtaa acgatcaaga
    28921 tattacaaaa ttaaaaaaca aagaattacg tacattccga aagaaaatcg gtatgatctt
    28981 ccagcatttc aacctgttat ggtcaagaac tgtacttgaa aatatccagc tgccgctgga
    29041 attagctggc gtaccaaaga gcaaacgtaa agaacgggca gaagaactgt tgcgtttagt
    29101 cgggttagaa ggacgcggac aagcatatcc ttcacaactt tccggcggac agaaacaacg
    29161 cgtcggtatc gcacgagcat tggcaaatga tcctgagatc ctgctttgtg atgaggctac
    29221 tagcgcattg gacccgcaaa caacagaaga agtattagac ttattgttag cgatcaataa
    29281 gaaattgaat ttgaccatcg tcttgatcac acatgaaatg aatgtgatcc gcaaaatctg
    29341 caacaaagtc gctgtgatgg agttggggaa agtcgtagaa gaaggagacg tattgactgt
    29401 cttcagacaa ccgaaaaaag aagtaaccaa acgctttgta caacaagaca tcgaaccaga
    29461 agctgattcg acagaactat tagctgaact catcaaagaa aatccaagcg gccgtttggc
    29521 aactttgacc tttagcgaaa gaaatgccaa cgagccagtc atttcccaag cgattcgacg
    29581 ctataacatc gatgtcaacg ttgtgtatgg aaagatcaaa caagtgaaag aaggttcctt
    29641 tggttcattg actgtcttga tgactggtga aaccaaagaa ttagatcaag cagaagtgtt
    29701 catcaaagaa caaggagtag gaattgaggt gatccatcgt ggataaaagc ttttcagaaa
    29761 catatctaga ttttaaacaa atcaacccgg aaacgatgaa tcaggctatc cttgatacac
    29821 tatatatgac attaatctca atggtcttag tgacgatcat cggattagtt ttgggattga
    29881 tcctttactc tattggacgc aaaaacaaac cgtatgctcg aatcatttat ggaatcgtat
    29941 cgatcatcag taatattttc cggtcaacgc catttatgat cctgatggtt ttgatcattc
    30001 catttactaa agcaatcgta ggcactatgc taggtgcgca agcagccatt ccagctcttg
    30061 ttttatccgc agcaccattt tatgcccgtc tagtagagat tgcttttcgt gaagtcagcc
    30121 ctggtgtact ggaagcagca gatgcaatgg gagcaagtta ctgggaaatc atctggaagg
    30181 tcttgatacc tgaaagtatt cccgcattga tttctggatt aacagttaca acgatctcga
    30241 tgatcggatt tactgcgatg gccggcgcga tcggcgcagg tggacttgga ggtcttgctt
    30301 ggcaggaagg ctaccagcgt ggtaatctaa cagtgacatt cgttgcgact ttaattattt
    30361 tactaatcgt atttatcgtt caaggaatcg gtgatttctt aactaagaaa acagacaaaa
    30421 gataatagga tataggggga tgtaggatat gaaaaagaaa atttttggat ttgcagcagc
    30481 gcttttgctg actgtaggat tagcagcatg cggtaacaac agcgacagca aagattcagc
    30541 aaataaagca gacgacacga cattgaaagt cggcgcttca ccgacaccgc acgcagagat
    30601 tttggaacat gtgaaaccat tattgaaaga tgaaggaatc gatcttgaaa tcgtcaaatt
    30661 cgatgactat gtattaccga accaatcttt ggaagaaggc gacattgatg ccaattactt
    30721 ccagcatatt ccttatttga acaaagaaat caaagaaaaa ggatatgact ttgtcaatgc
    30781 cggtgctgtc cacatcgaac caatgggctt gtactctaaa aaagtcaaag atgtttccga
    30841 attaaaagat ggtgcaacaa tcattacttc aaattctgaa tcagactggg gacgcatcat
    30901 cacaattcta caagatgctg gcttagtcaa agtcaaagat ggagtagatc tggaaacagc
    30961 aacattcgat gatattgaag aaaaccctaa gaacttgaag ttcaaccata cgatcgaccc
    31021 atcactttta gcttctacgt accaaaatga tgaaggtgac ctagttgcaa tcaacgcaaa
    31081 cttcgcttac ggcgcagggt tgaatccatt agaagatgcc gtattgcttg aaaaggacaa
    31141 ctctccttac gtgaatatta ttgcgactcg taaaggtgat gaagacagtg acaaaatcaa
    31201 aaaactgatt gaagtgcttc accgcaaaga agtccaagaa tggatcacag acaaatgggg
    31261 cggctctgtt aaaccagtaa aggctgatgc aaaataaggt atggaacaaa aaagatgaga
    31321 aataagtctg taatggctta tttctcatct tttttatacc tattctaatt tagaaatcaa
    31381 aattgtttaa taataaataa aagatatttg attttagtaa ggaaggtcat tgcgcttcat
    31441 tctcaattag tctaaaatga gtgagaacga aagagaattt gggggtataa tgcatgtctg
    31501 tcttagaaat aaaaaatcta catgtgtcga tcgaggaaaa agaaatcctt aaaggcgtaa
    31561 acctaacaat gaaaaccgga gaaatccatg ccatcatggg acctaacggc acaggaaaat
    31621 ctaccttatc tgccgctatc atgggcaatc caaactatga agtaacagaa ggcgaaattt
    31681 tgtttgacgg gaaaaatgtt ttagacttgg aagtagatga acgtgcgcga cttggcttat
    31741 ttttagctat gcaatatcca agtgagatac caggtatcac gaatgcggaa ttcatgcgtg
    31801 cagcgatcaa tgcgaaacgt gatgaaaacg acaaaatttc tgttatggca tttttgaaaa
    31861 agttagatga aaaaatggct ttactaaata tgccagaaga aatggctgaa cgttatctga
    31921 acgaaggttt ttctggcgga gaaaagaaac ggaatgagat cctgcaattg ttgatgttag
    31981 aacctacatt tgcaatttta gacgaaatcg attcaggtct ggatatcgat gctttgaaag
    32041 tcgttgctaa aggagtaaat gaaatgcgcg gagacaattt cggtgcattg atcatcaccc
    32101 actatcaacg attattgaac tatatcacac ctgatgtcgt tcacatcatg atggaaggcc
    32161 gagtagtcat gacagggaat gctgacctag ctaaacgtct ggaagcagaa ggctacgctg
    32221 gtatcagtaa agaattagga atcgactata aagaagaaga agcgtaaggg ggagcaagaa
    32281 tgaaagaaaa aaactggctc gattatcttg acgcggtaaa tgatttttct ttaagtaaag
    32341 gcgaacctga ttggatgaga accttccgtc aagacgcact agcgaaagca gatgaactgc
    32401 cattgccgca tatcgatcgg gtgaaattcc atcgctggtc gttatttgat gtgaaagaaa
    32461 cacaaaccat cagtgaaaca ggcacgattc cggcatttga tgcaatgaaa gacaatcctg
    32521 tgcttgtcca acaaggttca tggacgattt ttgaacaact gcctgtggaa ttagcagaaa
    32581 aaggagtcat ttttaccgac ttgttcactg caatgatcga atatccagaa ctagtccaag
    32641 aatattatat gaaaaaagca gtaaacatga acgaagacca attgactgca ctccatgtag
    32701 cttttatgaa cagcggtatt ttcctgtatg tgcctaaaaa tgtcgtgatc gatgaaccac
    32761 tcgagtcctt attcattcaa gatggcgcat ccgatgagca cttcttcaag catgtgttga
    32821 tcgtggcaga tgaacatagt gaattttctt atctggaacg tttccagaca accaaagaac
    32881 aagtagcaaa atcatcaggt aatatcatcg tggaagtcat cgctaaagct ggttcaaaaa
    32941 tcaaatattc agccgtagat caattaggag aaaatattac ttcttatatg aatcgccgtg
    33001 ggcacatttt acgagatgct tctgtcgact gggcaattgg tgtcatgaat gacggtcatg
    33061 tgatcgctga ctttgactca gatttagcag gagaaggtgc acacgcagaa gtcaaaatcg
    33121 tggcaatcag ctcgggcaga caaatccaag gaatcgatac acgagtaacc aataaagccc
    33181 ctcatacgat cgggcatatt ttgcaacacg gagtgatccg agaaaaagga acattgacct
    33241 ttaatggtat cggccacatc ttgaaagggg caaaaggtgc agatgcccaa caagaaagtc
    33301 gtgtcttgat gctttctgat aaagcacgtg gtgatgcgaa tcctattctt ttgatcgatg
    33361 aaaacgaagt aactgctgga catgctgcca gtgtaggacg agttgatcca gaagaaatgt
    33421 actatctgat gagtagagga ttgcataaag aagaagcaga gcgcttagtg attcgaggat
    33481 tcctcggttc tgtcttaaca gcaatccctg tagaacaagt tcggaaagaa ttagtcgaag
    33541 taatcgaagg gaagttgaat ggatgatcga tgctaaaaag ctacgcaatg attttcctat
    33601 cttatttcaa gacgtcaatg atgaaccttt agtttatctg gataatgcag cgacgaccca
    33661 aaagccaaaa caagtactcc aggcattagc gtactattac gaacacgata acgccaatgt
    33721 tcatcgcggt gtccatacgt tagcagaacg cgcgacccat gattatgaac aagcaagaga
    33781 aaaagtacgg gcgttcatcc atgcaaaaga aacagcagaa gtgctgttta ctcgtggtac
    33841 gacgacaagc ttgaattggg tagccagaac cttcggcgac cgctatatca aagcaggaga
    33901 cgagatagtg ctctcttaca tggaacatca ttctaatgtt atcccgtggc agcagttggc
    33961 aaaacgaaca ggtgctgtct tgaaatatat cgaactaaca gaagaaggct tcctggatat
    34021 ggaggatgca gcgaaaaaga ttacggacaa aaccaaaatc gtctccattg ctcatgtatc
    34081 caatgtctta ggtgtcttca atcctgttca agaattagct gaacttgtcc atgaaaacgg
    34141 cggggtcatc gtagtagatg gtgctcaatc tgccccgcac atggccattg atgtccaagc
    34201 actagactgt gatttctttg ctttcagcgg acacaaaatg tgcggaccaa caggtattgg
    34261 tgttttatat ggtaaacgaa aatggttaga agaaatggaa cctgttgaat ttggtggcga
    34321 aatgatcgat tttgtcgaat tatacgacag tacatggaaa gaactacctt ggaaattcga
    34381 agcagggaca ccaaatatcg ccggcgctat cgcattaggc catgcaatcg attatttgca
    34441 aaaactcggt atggacaata tccatcgata tgaagaagaa ctagccgctt atgtgttgcc
    34501 aaaattacaa gcaattgatg gattgactgt ttatggtcca caagacccga attttcggac
    34561 aggagtcgtt gcattcaatt tggatgggtt acatccccat gatgtcgcga cagctttaga
    34621 catggaaggg gtagccgtca gagcaggtca tcattgtgcg caaccgctat tgaagtacct
    34681 tgaagtatca gcgactgctc gcgcgagctt ttatttctac aacacaacgc aagacgccga
    34741 ccgtttagtt gaagcaatca tggcaacaaa ggagtttttc caacatggga ctatctaaat
    34801 tagacaattt ataccgtcaa gtgatcttgg atcattcttc ccatccgcat catcgtggaa
    34861 gcttgactga ctcgacaagc aagatcgaat tgaacaaccc cacatgtgga gatgtgatcg
    34921 aattgcaagt cgatgtaaaa gacggaatca tcaaaaatat cgcctttgac ggcagtggct
    34981 gctccatcag tacggcaagt gcctcgatga tgacagacgc cgtcatcgga aaatcaatag
    35041 aagaagcaga acatttaact gtagactttc tacagcttgt ccaaggaaaa gaagtcaaag
    35101 atcccgacca attaggcgat gctgctatgc ttggtggtgt agctaaattt cccgctcgga
    35161 tcaaatgtgc gacacttgcc tggaaagcac taggaaaagc aatggaaaac gatggtaccg
    35221 cagctttcca tcattaccac aaggaagagg agtgagaaca tgggcgtacc agaattagaa
    35281 gaatataaat tcgggtttca cgatgatgtc gaaccggttt tcagtacagg agaaggcttg
    35341 acagaagaag tgatccgtga gatgtcaaga atcaaaggcg aaccagaatg gatgcttgaa
    35401 ttccgtctga aatctctaga aacatttaac aaaatgccaa tgcaaacatg gggccccgac
    35461 ctttcagaca tcgatttcga tgccatcaaa tattaccaaa aaccaagtga caaacccgct
    35521 cgtgactggg aagacgtacc agaaaaaatc aaagatacat ttgaaaagat tggtatacca
    35581 gaagctgaac gagcttatct agccggtgct tccgcacaat atgaatcaga agtcgtgtac
    35641 cataatatga aagatgaatt cgaaaagtta ggaatcgtct ttactgacac tgactctgct
    35701 ttgaaagaat accctgaatt attcaaagag tacttttcaa aacttgtacc gccaaccgac
    35761 aacaaattag cagcgctgaa ttcagccgta tggtcaggtg ggacctttat ttacgtgcca
    35821 aaaggcgtca aagtcgatgt tccattacaa acgtacttcc ggatcaatgc ggaaaacacg
    35881 gggcaattcg aacgtacgct gatcattgtt gacgaaggag caagcatcca ctatgtcgaa
    35941 ggttgtacgg cacctactta ttcaagtaac agcctgcatg ccgccatcgt agaaatcttt
    36001 acaagaaaag atgcgtattg ccgttacaca acgatccaaa actggtcaga caatgtgtac
    36061 aacttagtaa ccaaacgagc aaaagcatac gaaggcgcaa ccgttgaatg gatcgacgga
    36121 aacctaggtg caaaaacaac gatgaaatac ccaagtgttt acttagatgg aaaaggtgca
    36181 cgaggcacca tgctctccat cgcctttgca ggagcaaacc aaatccaaga tacgggtgca
    36241 aaaatgatcc acaatgcacc aaatacatct agctctatcg tctctaaatc aatttcaaaa
    36301 gacggcggag aagtaaacta tcgaggacaa gtaacctttg ccaaaaacag tgcgggttcg
    36361 atctctcata tcgaatgtga cacgatcatc atggacgaat ggtcgaaatc cgatacgatc
    36421 ccattcaatg agatccacaa cagccaagtc tctttagaac acgaagccaa agtctcaaaa
    36481 atctcagaag aacaactcta ctatctgatg agccgaggcc tgaccgaatc tgaagcaact
    36541 gaaatgatcg tcatgggctt tgttgaacca ttcaccaaag aacttccaat ggaatatgca
    36601 gtcgaactca atcgattgat cagttatgag atggaagggt ctgtaggtta ataactattt
    36661 cattgctcga aacgttgata ttaaagcgtt tcgagcgttt ttttatttgt attttaatgg
    36721 ttggctacgt ttttggctac gtttggaatt attcgcccat aaattttgca aatcggtcac
    36781 cagttttctt aacagattgt ggtgtgacat gagcatagat attcatggta gttttaatat
    36841 ctttatgacc taatcgttcc tgtacttctt ttatcgacgc accactttca aacaataagc
    36901 tacagtgggt atgcctaaat ccatgtggag taatttgagg ctccatcggt gtctttttgt
    36961 aaatccagtc taaccaatcg tttactactt gggggtagta caacttgttt gtgtttgtag
    37021 tgaaaagaaa ctgttttggt gaattcgtgt tatagccata taagatcatt attttcattt
    37081 gttcttgttg ccaaatacgc agttgtttaa gtgtaaaatc atcaagctga atcgttcttg
    37141 atgaattttt agttttaggt acttgtagaa ctacttgatt aaactcgtct tgagcgatag
    37201 ttttaccaat tgttattgtt ttattgaaat agtctatatc ttcccattga agcgccaatg
    37261 cttcgctttt acgcattcct gtataagcta ataaacggaa aaaagtgtac agtttaactg
    37321 aattattttc tttagtattc tgtaaaaaca gttgtaattg atctttcgtg taaaacttca
    37381 agggttgttc ttcttcaatt tttcttggaa gcaatgtttt agacatagga ttatccttac
    37441 agacttccat tgctactcca aatttaaata tttgagcagt tgtttttctc aagaaaccat
    37501 attgttttaa tgttttgtgc cattcattca cctgtttttg gcaatagcta acacttattt
    37561 tatccaatcg taattcccca aaagcaggta atatatggtt tttgcaaaaa cgttgagcaa
    37621 cggcaacaga agacggtttt actcttgttc tgtagttatc aatccataat tcatacaact
    37681 cttgaaaagt tgtaacattg attttaaact cttgtttttc tttaaagtct acaagtagtc
    37741 tattaagtgc tgtttgcgcc tcagcttttg atttgaatct tctacgcttt gtacgtatat
    37801 cttttccagt cttgggatct ttccctaaat aagtttcaaa tccccaatat ttttcgccat
    37861 tttgtaattt ataactaaaa aatgttgcca tttgattctc tccttacttc attattgcag
    37921 gtagagaagt tatttgaaga
//
LOCUS       DAZKCW010000027        34765 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000027 DAZKCW010000000
VERSION     DAZKCW010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.027"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            669..1358
                     /locus_tag="ACG84Z_001478"
     CDS             669..1358
                     /locus_tag="ACG84Z_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFP9162329.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1345..2553
                     /locus_tag="ACG84Z_001479"
     CDS             1345..2553
                     /locus_tag="ACG84Z_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFP9162330.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2847..4118
                     /gene="serS"
                     /locus_tag="ACG84Z_001480"
     CDS             2847..4118
                     /gene="serS"
                     /locus_tag="ACG84Z_001480"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFP9162331.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4667..6151)
                     /gene="guaB"
                     /locus_tag="ACG84Z_001481"
     CDS             complement(4667..6151)
                     /gene="guaB"
                     /locus_tag="ACG84Z_001481"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFP9162332.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6656..7351)
                     /locus_tag="ACG84Z_001482"
     CDS             complement(6656..7351)
                     /locus_tag="ACG84Z_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFP9162333.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7441..8541)
                     /gene="ychF"
                     /locus_tag="ACG84Z_001483"
     CDS             complement(7441..8541)
                     /gene="ychF"
                     /locus_tag="ACG84Z_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFP9162334.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8550..8741)
                     /locus_tag="ACG84Z_001484"
     CDS             complement(8550..8741)
                     /locus_tag="ACG84Z_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFP9162335.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8762..9652)
                     /locus_tag="ACG84Z_001485"
     CDS             complement(8762..9652)
                     /locus_tag="ACG84Z_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFP9162336.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9639..10406)
                     /locus_tag="ACG84Z_001486"
     CDS             complement(9639..10406)
                     /locus_tag="ACG84Z_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFP9162337.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10418..11131)
                     /gene="rsmG"
                     /locus_tag="ACG84Z_001487"
     CDS             complement(10418..11131)
                     /gene="rsmG"
                     /locus_tag="ACG84Z_001487"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFP9162338.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11363..13264)
                     /gene="mnmG"
                     /locus_tag="ACG84Z_001488"
     CDS             complement(11363..13264)
                     /gene="mnmG"
                     /locus_tag="ACG84Z_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFP9162339.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13281..14678)
                     /gene="mnmE"
                     /locus_tag="ACG84Z_001489"
     CDS             complement(13281..14678)
                     /gene="mnmE"
                     /locus_tag="ACG84Z_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFP9162340.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14977..15360
                     /locus_tag="ACG84Z_001490"
     CDS             14977..15360
                     /locus_tag="ACG84Z_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162341.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15528..16286)
                     /gene="jag"
                     /locus_tag="ACG84Z_001491"
     CDS             complement(15528..16286)
                     /gene="jag"
                     /locus_tag="ACG84Z_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFP9162342.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16304..17122)
                     /locus_tag="ACG84Z_001492"
     CDS             complement(16304..17122)
                     /locus_tag="ACG84Z_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFP9162343.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17119..17475)
                     /gene="rnpA"
                     /locus_tag="ACG84Z_001493"
     CDS             complement(17119..17475)
                     /gene="rnpA"
                     /locus_tag="ACG84Z_001493"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFP9162344.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17593..17727)
                     /gene="rpmH"
                     /locus_tag="ACG84Z_001494"
     CDS             complement(17593..17727)
                     /gene="rpmH"
                     /locus_tag="ACG84Z_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFP9162345.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18250..19584
                     /gene="dnaA"
                     /locus_tag="ACG84Z_001495"
     CDS             18250..19584
                     /gene="dnaA"
                     /locus_tag="ACG84Z_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFP9162346.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19782..20912
                     /gene="dnaN"
                     /locus_tag="ACG84Z_001496"
     CDS             19782..20912
                     /gene="dnaN"
                     /locus_tag="ACG84Z_001496"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFP9162347.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21141..21383
                     /gene="yaaA"
                     /locus_tag="ACG84Z_001497"
     CDS             21141..21383
                     /gene="yaaA"
                     /locus_tag="ACG84Z_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFP9162348.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21370..22494
                     /gene="recF"
                     /locus_tag="ACG84Z_001498"
     CDS             21370..22494
                     /gene="recF"
                     /locus_tag="ACG84Z_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFP9162349.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22491..24437
                     /gene="gyrB"
                     /locus_tag="ACG84Z_001499"
     CDS             22491..24437
                     /gene="gyrB"
                     /locus_tag="ACG84Z_001499"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFP9162350.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24457..26928
                     /gene="gyrA"
                     /locus_tag="ACG84Z_001500"
     CDS             24457..26928
                     /gene="gyrA"
                     /locus_tag="ACG84Z_001500"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFP9162351.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27164..27463
                     /gene="rpsF"
                     /locus_tag="ACG84Z_001501"
     CDS             27164..27463
                     /gene="rpsF"
                     /locus_tag="ACG84Z_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFP9162352.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27513..28025
                     /gene="ssb"
                     /locus_tag="ACG84Z_001502"
     CDS             27513..28025
                     /gene="ssb"
                     /locus_tag="ACG84Z_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFP9162353.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            28051..28287
                     /gene="rpsR"
                     /locus_tag="ACG84Z_001503"
     CDS             28051..28287
                     /gene="rpsR"
                     /locus_tag="ACG84Z_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFP9162354.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28430..30403
                     /locus_tag="ACG84Z_001504"
     CDS             28430..30403
                     /locus_tag="ACG84Z_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFP9162355.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30409..30861
                     /gene="rplI"
                     /locus_tag="ACG84Z_001505"
     CDS             30409..30861
                     /gene="rplI"
                     /locus_tag="ACG84Z_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFP9162356.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31135..32502
                     /gene="dnaB"
                     /locus_tag="ACG84Z_001506"
     CDS             31135..32502
                     /gene="dnaB"
                     /locus_tag="ACG84Z_001506"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFP9162357.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33282..34574
                     /locus_tag="ACG84Z_001507"
     CDS             33282..34574
                     /locus_tag="ACG84Z_001507"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFP9162358.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10587 a         6759 c         6870 g        10549 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcagg agtgtttccc gattcgtttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa gtaattgtca actctttttt aaaagttttt tcgatttcgt
      181 ttttcgaaat cttccagcaa ctcatttatc ataacttatc gtttgttatt tgtcaagaac
      241 ttttttgaag tttttttcga tagaatcaag cttcgcaagt ggttcttttt taacgactca
      301 gttatcttat catgtcattt ccaacatgtc aacaacttat tttttattat ttaataagtt
      361 attggtgttc ttttgaacaa ataataatat atcaacatca catgtgaaag tcaataagaa
      421 aatgcttatt tatcaacatt tctagcttac atgatcattg gttagttctg gtcctttttc
      481 gttcgtcttt ataactccga gagacgtaaa atccttttgt tttcagttta atgttcatgt
      541 tcttgtctta ttcacaccaa ctagatgtct caccttctaa aattttcctt aacaaagtgc
      601 tgcttttatc tatttctgct tttttttgct agaataatag taacaatatg actctggagg
      661 atttatttat gaaaattttg attgctgacg atgataaaga aatcgttgaa ttattaagta
      721 tctatgttca caatgagggg tatgaagcag taaaggctta tgatgggaaa gaagcattat
      781 ctaaaatcag aacaatccct gatattgaat tacttatttt agatatcatg atgcctgaga
      841 tggatgggat gcaagtagtg aaagagctac gaaaagaatc ccaaatacca atcattatgc
      901 tgacagcaaa aactactgat atggataaga tcaaaggact ggtcgctggt gcagatgatt
      961 atgtgaccaa gccatttaat ccgttagaag taatggctag agtaaagtct ttattacggc
     1021 gtacaaaaat gcagattgcc ccagatcagc ctgatgtatt agaagtaaat gcattaatca
     1081 tcaataaaga ctctcatgaa gttaaaacaa tcgatgggaa agaaatccag ttaacagctt
     1141 tggaattcgg tatcctctac ttgcttgcta gtcatcctaa tcgagtattt agcgcggatg
     1201 aaatttttga gcgtgtttgg aaacaagaaa gtattgtctc tgctaaaact gtcatggttc
     1261 acgttagtca tttaagagat aagattgaag aagcaactgg tggtgaaaaa gtcattcaaa
     1321 ccgtttgggg agtgggctat aaaattgacg caagatagta aacgagcaac tgaaaaacgc
     1381 cgtcggatca atttgacttc aaaagaaatc agcgaattgt tagcggaagg aatcatcacg
     1441 attatccttt tgcttctatt aaatgtttct attctggttg ttatcagttc ggtgatcaac
     1501 agttcacctt ctttgacgaa tgcgatttgg gattcaaaga atatttttgc agaacgattg
     1561 aacactgatt tgttctggaa cggccggaat tttattattc cctttttctt tctattagat
     1621 attggtgttt tgtattggcg cttgattcga agatatcgcc aaatgcaatt gcggcatatc
     1681 atcagcgaac ttcactacat cgcaaacgga aattatgatc atcgtatccc ttttgaactg
     1741 agtggtgact taagccgagt ggtaacaagt atcaatggat tggtggatag taccgtagca
     1801 gcgattgaag acgaacgtaa aatcgaaaaa tcaaaagatg aattgatcac gaatgtcagt
     1861 catgatatcc gtaccccact cacgtccatc attggatacc taggactgat agaagatggc
     1921 cagtatcact cagaagaaga tcttttaaag tatacgcata ctgcttatat caaagcaaag
     1981 cagatgaaat ctttagtgga cgacttattt gaatacacta aggtacgcca gcctgctgtc
     2041 ccggtgaatt tttctgcctt tgacatgatc cagttgatcg aacagttagc agctgatttt
     2101 gagttggaag cttctaaaaa aaatatccaa atacttgttc aatcaaaagt agactccctt
     2161 atcatggatg gcgataccga aaaacttgta cgtgtcttca ataatctttt gacgaatgcg
     2221 ttgaaatacg gaaaaggagc aacgaagatc gtaatcgaag tagaacgtat cggttcagaa
     2281 gttgttgcaa cagtcaaaaa taacggagca atgatcccac aacaggcaat cgataatcta
     2341 ttcgaccgtt tttatcgtgt agaagaatct cgttcacaag caactggagg aactggactt
     2401 ggtttagcaa tcgctcaaag cattgtggct ttgcacggcg gatacattta tgcaaaatca
     2461 gataagcaat ggacttcttt catcatgcac cttccaatca agaaaaatga aaaattacct
     2521 attgatacac aggaagttat tgacgaaagc tgaaatattc gctattctta ttacaattat
     2581 tagaataaat gaaaaacaca gaacccagta cactttattc tttttcagag agctgatggc
     2641 aggtgtaaat cagcaaagga taatttggaa gttccagttc gtttacgtgc cctttcgaaa
     2701 taagaaaggt cggttcaaca gccgttatgt gttcaacaag tgcagctgac gctgaacttg
     2761 ggtggtaccg cgaatttcag actgattcgt cccaagaata atgggatgga tcagtctttt
     2821 tttattttca aaaaggagga aatcatatgt tagatgtaaa aatgatgcga caaaatattg
     2881 aagaagtaca agaaaaattg atgactcggg gcgtaaaaaa agaaacatta gctgaattca
     2941 tggaactaga tgaaaatcgt cgtaagctac tagtcaaaag tgaagaatta aaaaaatatc
     3001 gaaatgatgt ttctgctgag atcgcccaat tgaagcgtgc aaaagaagat gcttctgcta
     3061 aaatcgctga aatgaaagaa gtcggtggca acatcaaagc attggatact gaaattgctg
     3121 aagtggatga aaaattgaaa caaattgcaa ctactttgcc aaaccttccc catgattctg
     3181 tgccagttgg aacagatgaa gaggacaatg tagaaatccg tcgttggagc gaaccacgta
     3241 catttgcttt tgaaccaaaa ccacactggg aaattgcaga aaatcttgat attttagatt
     3301 ttgaacgtgg cgcaaaagta gccggtagcc gttttgtcta ttacaaagga ttaggtgctc
     3361 gattagaacg tgctgtctac aacttcatgc ttgatcagca tatttacgaa cacggctata
     3421 ctgaaatgat cactccttat atcgtcaaca gtaaagcgat gtttggtacg ggacaatttc
     3481 caaaattcaa agaagatgtt ttccaattgg agaatactga tctaacatta atcccaacag
     3541 ctgaagtacc attaactaac tattataatg atgaaatttt agatggtgca gatttaccta
     3601 tttatttcac tgcactaagc cctgcttttc gttctgaagc cggaagtgct ggtcgggata
     3661 cacgaggact gattcgtctt caccaattca ataaagtaga aatggtcaaa ttttcggatg
     3721 tagagcattc ttacgaagaa ttggaaaaaa tgacagctga tgcagaagat atcttgaaaa
     3781 aattgcattt gccttatcgt gtgatggcct tatcaactgg agacatgggc ttttctgcag
     3841 ctaaaactta tgacttagaa gtatggatac ctgcacaaga tacttatcgt gaaatcagtt
     3901 cttgttctaa ctgtgaagat ttccaagcac gccgcgcaat gatccgttat cgcgataatg
     3961 atggaaaaat ccactatact catactctga atggttcagg acttgcagtt ggccgtacag
     4021 tagctgccat tttggaaaac taccaaaatg aagatggttc tgtcacagtt ccagaagcgc
     4081 tcgttcctta tatggggaat ctgaaagtta ttaaataaag aggctgtgaa aaagccgctt
     4141 agtttcgagt attaagaaaa attttgtgaa aatggctttc cacatttttg cataaattgg
     4201 acttaatacc gagaaactgg cttttgaaca ccatttatcg agaggttgtg aaatcagcga
     4261 attaacctga gtattagaga aaaaaatgga aaaatagtcc ctcatatttt accgtttgtt
     4321 gaactaatac cgagggtcag ctgattgaac accgtttagt ggagaggtcg taagcctacc
     4381 ccccagctcc tagttacaag gacaaattca aaaaacagct cttcatattt tatgaatgtt
     4441 gtacttgtga ttcggaggtg gcaagggaac actgtttatt caaaaagagg ctgggacaga
     4501 agcgtttaac tccaagaaat aagaagaaat tcacgaaaat tgcttttcaa atttttgtga
     4561 atttcttctt atttccgaag gagttgcttc tacttccgcc gtttatacgt gtttagagcg
     4621 tgagacaaaa gtgttcttta cttttgtccc acgctcttta atgtttttaa gattcaactg
     4681 aatagtttgg tgcttctttt gtgatttgta catcatgagg gtgtgattct tttaatccac
     4741 tgccgctcat ttggataaat tgcgcttcat cacgtaattg ctgtagattg gctgccccaa
     4801 cataacccat tcctgaacgc aaaccgccga tcatttggaa aataatatct gcaacacttc
     4861 ctttataagc aacccgacct tcgattcctt ctggtactaa tttatttgct tcattgacac
     4921 taccttggaa gtaacggtct tttgaacctt tttccatcgc gcctaatgag cccatacctc
     4981 ggtatgtttt gaatcgacgt ccttggaaga tttcgaattc acctggtgat tcatctgtcc
     5041 ctgccaacat acttcctagc atcactgcat gtccgccggc agctaatgct ttgacgatgt
     5101 caccagaata tttgatccct ccgtctgcaa taatcgcttt gccatattga cgagcaactg
     5161 atgctgcatc ataaatagct gtgagctgag gtacacctac accggctacc acacgtgtcg
     5221 tacaaatcga tcctggtccg ataccaactt ttacgacatc tacacctgca tcatataaag
     5281 cttttgtcgc ttcagccgtc gcaacgtttc ctgcaatcaa tgttgcatct gcaaaagttg
     5341 aacggatttc ttgaattttt cggatcacac ctgcactatg tccatgagct gtatcgatga
     5401 tgattgcatc tgcccctgct tctaataaag cattcgcacg ctcaaatgta tcgcttgtta
     5461 caccaacggc tgctgctaca agcaatcgac catgttcatc ttttgctgca tttggaaatt
     5521 cgatcacttt ctcgatgtct ttgatcgtga tcaatccgct taaacgacct tcgttatcta
     5581 cgattggtaa tttttcgatt ttatgttttt gcaaaatctt ttctgcatct tttagagagg
     5641 tacctactgg ggcagtcact aagttgtctt ttgtcatcac atcagcaatc ggcatgtgat
     5701 aatctgttac aaaacgcatg tcgcggtttg taattatccc taccaatttt ctgttttcaa
     5761 gtgtttcaac gattggcaca ccactgatac gatatttgct catcaattct tctgcgtctg
     5821 ctacaagatg ctgtggcgtt aagaagaacg gatcaatgat tacgccactt tcagaacgtt
     5881 tgacttttct tacttcatcc gcttgctggc tgatcgtcat gtttttatgg atcacaccta
     5941 gtccgccttg tcttgccata gcaatggcca tcttgctgtc ggtaacagta tccatacttg
     6001 cactgatgat tggaatattc aacttaatat ttttagctaa ttgtacgctc atatccactt
     6061 cgtttggtaa cacgtgactt tctgctggta tcaataagac atcatcaaaa gtaaatcctt
     6121 ttttcgtgaa ctttgtttcc cagttggaca tttttagtac cactcctcta atttagttta
     6181 tctattaaaa taattgattt tttcatttaa gtcaatgatc tacttggaat caagttagct
     6241 ttctcataga ataccaatat aaagcgttta catctgtgtg tattaaaaga gattgtaaaa
     6301 aagctgtcct gcatcaagta ataagaacag ccaatcaaaa acagcttctc atgtttttga
     6361 attggttggg tttattaccg cagatgcaaa cttttgaaca ccgtttagtg gagaggctgt
     6421 gaaaaagctg cttagtttcg agtagtaaga aaaattttgt gaaaatggct ttccacattt
     6481 ttgcataaat tggacttaat accgagaaac tggcttttga acaccgttta tcgtaaaaag
     6541 ggactgtgac aagacttttg tcacagtccc ttactattat ttaactatgg ataaacaaaa
     6601 tgaggttctt tactacccct agatatctag caaaatagct gatctttttg ctagtttatc
     6661 ttcttgggac ggataaactt ccaataatcc cgtatttttt cttcaagtag taacggattg
     6721 ctaaagcagt tgccccgata atgataacta ctactggatc taatactgga ttgataactg
     6781 gtggcaatag tgttgtcgca gaaaacagta cgacccaaag aagtgtcgtt ccacctagga
     6841 taagcaatgt cttacccatt cctggtttct tgcttcgatc tgctccggga tattcatatt
     6901 gatagatgta tttgtacatc atataaaaga cccagccacc gattgcagaa cctagaacga
     6961 gtgtagaaaa gccataagct ggcgttgttc cacgtgaaaa caatccggta atcgcaatca
     7021 tgatacttaa tagaccaagc aacagcaacg tattatctaa ccacatcaat aaaggggtgg
     7081 atgaattttt tacttctgct ggcttattga tgattgcttc cgttctttca gagactgtcc
     7141 caaacaattg acgggctgtt cttccgcctt tttgttctgc aactaaagta ggcagaatgt
     7201 catgaagggc ttttactttt tcttcttcag acaaattcgc tgcttctaaa gattttttca
     7261 aatcaaaaat gtactgttga tttcttttgg ttaattttgt ttctaaacta ttgttttctt
     7321 ttacgattgc tcgtaattgt tctggttcca ttatctaata gtcctcctta gccgttcctt
     7381 ttctcaacgg tcgtcacaaa agacattcta ccatattcta cagctagttt gatagccctt
     7441 ttacacatta aagcggaata acattacgtc gccgtcttgt acgacataat cttttccttc
     7501 taatcgaaca cgtccagctt cttttgctgc atgcatgttt ccgtaatgat ccaagtcttc
     7561 aaaagagaca gtttctgcac ggataaatcc gcgttcgaaa tctgaatgga tgattcctgc
     7621 tgcttgtggt gctttgattc cttttttgaa tgtccaagca cgtacttctt gttccccagc
     7681 agtaaagtaa gtagctaagc ctaacaaatc ataagcagca cggatcaact gatccaaacc
     7741 tgattcttcg attcctaaag cttctaaaaa ttccgctttg tcttcttcat ctaattctgc
     7801 gatttcttct tctgcacgag cactgaccac gatcacttct gcattttctt ctgcagcaaa
     7861 gttgcgcact tcttgtacat aatgattcgc gtctgcatct gctacgtcat cttctgagac
     7921 attggctaca taaagaattg gttttgtcgt caataaaaat agtgatttaa cgattttttg
     7981 ttcttcttca gtaaattcga tcgttcgggc agattttcct tcttccagta caggtttgat
     8041 tttatccagt acagctagtt ctgccactgc atctttatct ttggttttag caacttttgc
     8101 tacacgagta tagcgtttgt tgatagattc taagtctgct aacactagtt ccaagttgat
     8161 cgtatcaata tcttctagtg gatcaacacg tccttctacg tgagtaatat tatcatcatc
     8221 aaaacagcga acaacgtgac aaatagcgtc tacttggcgg atatggctta agaattgatt
     8281 tcccaaacct tctcctttac ttgcgccttt tacgattcca gcaatatctg taaattcaaa
     8341 agtcgtcgga acagtttttt tcggatgtac aagttctgtt aagcgttgca aacgccagtc
     8401 aggtacttct accatcccta cgttggggtc gatcgtcgca aagggatagt ttgctgcttc
     8461 tgctcctgct tttgtgatcg cattaaacaa agttgatttt cctacgttgg gcaacccaac
     8521 aattccagca gtcaatgcca taaatttatt cactctttct ctgcattttt ttcaattact
     8581 ttttttaatt tcttttcaaa atctcgacgg gtcatcatga cgatatgtcc gcaattcata
     8641 catctgattt tgatatctgc gcccattcga atgacttccc agcgattcgt ctggcaagcg
     8701 tgaggttttt tcatttcaac gatatcgtgc aagtcgtaca taaaaatagc ctcctttttg
     8761 tttattcttc atcaaattga atattcaaga tatcaagaat tcgagtcaaa tctttttgag
     8821 aaagatattc aatctcgatc ttacctttcc catttttttc ttggatagct acacttgtac
     8881 caaatttatc catcaaacga tcttcgcttt ctcggatata atatggtttt tcctttgcta
     8941 gccttgggat ttttttcttt tcttttccat cattttgatt taactcagaa acaagctgtt
     9001 ccagttggcg gacagttaaa ttttcagtta ctgcacgatt ggctaatttc aagatcaatg
     9061 ttttattttt taaacctaac agcgtacggg cttgtcccat agataaacgc tgatcttgta
     9121 ccatttcctt gacaagatcc ggtaaagaaa gcaagcgcaa ataattggcg atataaggtc
     9181 tgctctttcc taaacgacta gctacttctg cttgtgttag tttcaggttt ttcatcagca
     9241 tctcatatgc ttctgcttct tctaacggat tcagatcttc tcgctgcaag ttttccagca
     9301 ctgctacttg catcatcgct tcttcgtcaa agtctctaac gatagcaggg atcgtttctt
     9361 tttcagctag tttggacgct cgaaaacgtc gctcccctgc aataatctca tatcctttta
     9421 ctgcggaacg gcgtacgatg atgggttgaa agacacctga ttgttcaata gaattagcta
     9481 gttcctgcaa agatacttct tcaaatgttt tacggggctg atacggattt ggtcgcagct
     9541 cattcaatgg tagctggaca acggtatcat cttttacatc caccgtctct aagttttcta
     9601 aatcttgaaa cagtgcatcg attcctcggc ctaatccttt acttttcttc acgacttacc
     9661 acttcctttg ccaatgcttg gtagacttca gctcctcgag aacgtggatc gtagtcgatg
     9721 atcggttttc catgactagg tgcttctgat aaacgaatat ttcttggaat gatcgtttcg
     9781 taaacttttt cgcggaagta tttacgtact tcttctacga cttcatttcc cagatttgtt
     9841 cgtgcatcat acattgtcag taagactccc tcgatctcta attctggatt aaagtgtttt
     9901 tggactaaac gaaccgtatt cagtaattgg cttaatcctt ccaatgcgta atactcacac
     9961 tgaacaggta tcaaaatcga atcacttgct gtaaatgaat tgattgtcag atggccaaga
    10021 gaaggcgggc aatcgatcaa aatataatca tactgactgc ttacttctgc taaagatcct
    10081 tttaatcttg attctcttgc catcattgac gtcaattcga tctctgctcc tgctaattgg
    10141 agagtcgcag gcacaatact caaattttcg tgttcagtga tcaaagttgc ctcatcaatt
    10201 ggcaattcat tgactagaac atcatagatg tctcttgtca catcaggttt tctgatcccg
    10261 acaccactgg tagcatttcc ttgtgcatcc atatccacta gcaatacttt tttgccaagg
    10321 ctagcaagac aagcacctag attcaccgtc gtcgttgttt tgccgacgcc acctttttgg
    10381 ttcgcaacag atattatttg tgccatctct tctcctccta tttgattggc tgcttattag
    10441 gcagtccggg ctttcttggg tatttctttg gggttggttt ctttttttga ataacgatga
    10501 tatgccgttg atcagagaca ttcggcaagg taaccgcctc ttctttgagg aatttaccac
    10561 ctaataaagc aatcgcttgt tttgcttctg tcaattcctc ttcacttttt gctgctttca
    10621 atgcataaaa atagccttct tgtttagcca agggcaaaca caattccgct aacacattca
    10681 aacgagcaac cgcacgagca gtgacaaggt caaatgatgc acgaaagtga ggattttgcc
    10741 caaatgtttc tgcccggtca tgatataagg aagcatcgat tcctaataat cgggttaact
    10801 cagataagaa ggttattcgt ttattcagag aatcaacgat cgttatctgc agttctggaa
    10861 aggcaatttt taaaggtatg ctaggaaacc ctgcccccga accaacatcg cataaagata
    10921 aaggttgcgt aaagtctact tcaaatgcta atgtaagtga atcgtaaaaa tgcttcagat
    10981 atacgtcttt ttcatccgta atagctgtaa ggttcatctt ttcgttccat tcgactaatg
    11041 tccgataata aatagcgaat tgattcattt gatgatcggt aagctctatc cctttttctg
    11101 ccaaggattg gcgaaattct tctggtatca taaatattcc tttcattgtg aaacagcaat
    11161 tgtttcacag attctctccc tactttaacg caaaatctct agacatgcaa tccttccata
    11221 tggattctta aaaatttgaa aagtaagaaa agccgataga ctttttcttt ctagtatgac
    11281 tcataaaata tacacagaag agagaactag ctttgagcaa tttctgcaaa aactagttct
    11341 ctcttctatt tattattacg tattacgctg gttcactgac tttcgcaatc ttcccttgtt
    11401 cgatatagac cattaggata cttaggtctg cagggtttac gccactgatt cggctagctt
    11461 gggcaattgt ttctggttgg attttctgca atttttgttt tgcttctgtt gctaatccgt
    11521 tgattgctgc gtagtcgatg ttttctggaa tctttttcgc ttccatgcgt tttaattttt
    11581 ctactttttc catggctttt ttgatgtagc cttcatattt gatttggatt tctacttgtt
    11641 cgatttcttt tcgtgtcaat tcttcatttt ctggaataaa ccgtagaagt tctgcataag
    11701 taatctcagg acgtcttaaa aagtcgcttg ctagtacacc atcttttaat ggtgccgcat
    11761 taatcgttgc taaaaagtct tggacttctt ctgttggttt gattcgtaca ttcatcaaac
    11821 gtttgatttc ttgttcaact gcttcttttt tcttcaaata attcttgtat tgatcttctt
    11881 ttactaagcc tacacggtga cccatttctg ttaatcgcaa atctgcatta tcatgacgta
    11941 aaagcagacg gtattcagca cgtgaagtca gcaaacgata aggttcgttc gttccttttg
    12001 ttaccaaatc atcgatcatg acaccgatgt aaccgtcact tcgtttgatc actaaaggtt
    12061 cttttccctg aactttcaaa gctgcattga taccggcaat cagcccttgt ccagccgctt
    12121 cttcataacc gcttgtacca tttgtttgtc cagctgtata aagattttca acgactttag
    12181 tttctaatgt cggacggagc tggtgtggct ctactacgtc atattcgata gcatatcctg
    12241 tacgcatcat ttctactttt tctaatccag caatagaatg aagcatgttg acttgaacat
    12301 cctctggtaa agaagtagat aaaccttgaa catagacttc ttccgtattt aagccttctg
    12361 gttccaaaaa taattgatga cgtggtttgt ctgcaaaacg cacgatctta tcttcgatgg
    12421 atggacaata gcgagcgcct accccttcaa cgatccctgt aaacattggg gcacgatgta
    12481 agttgtctcg aataatttgg tgagtcgtct cacctgtata ggtcagccag caagattcct
    12541 gatctagttt ataggcacta tctggtgtgc tgaagctaaa atgattcggc tctttgtcac
    12601 caggctgctc ttctgtaaca gaatagtcga tcgtacttga ttttactcga ggcggtgttc
    12661 ctgttttgaa ccgttcgata gcaaagccaa gttcttttag atgattcgct agtccaatag
    12721 aaggttgaga gttattcgga cctgatgaat atttcaattc accgataatg atttctccgc
    12781 gaagtgctgt tccggctgta ataacaactg ctttggcccg gtagctcgct cctgtggacg
    12841 tcactactcc atgacaaaca ccatcttcga cgatcagttc ttcgacgatt ccttgtctta
    12901 gcgtcaaatt tggttctttt tcgatcgtat gtttcatttc tgttgaataa gcatgtttgt
    12961 ctgcttgtgc tcgcaatgct cggacagctg ggccttttcc tgtgttcaac atacgcattt
    13021 ggatataggt tttatcgata ttcttaccca tttctccgcc taacgcatcg atttctcgaa
    13081 cgacaacgcc tttagctggt ccgcctacag aaggattaca tggcatgaat gctaccatgt
    13141 ccaaatttat tgtcagtaat aatgtttttg atcccatacg tgcagcagca agtgcagctt
    13201 ctgaaccggc gtgtcctgcg ccaacaacga tcacgtcata cgcatctgct tcataatgtt
    13261 ccaatcgttt gttcctcctt ttattttcct aaacaaaatt gactgaataa ttgagtgatt
    13321 agctcatctt gtacactgtc gccgacaact tctcctagat agtcccagca acgcgtcata
    13381 tctatttgaa cgagatccac aggcattcct gaatcaatac ctgcaatgac ttcttcaagt
    13441 gagagggaag ctttttctaa caacgcgata tggcgggtat tagaaacata agtagcgtct
    13501 ctttctcctg tttctccgct gaagaataaa tcagaaatag ctgattccaa acgatctagt
    13561 ccgtcgtttt tagctacgga aattgaaaaa actggttcat tttcgatcaa tttcttcaat
    13621 ttttcttgtt ccagctgtgc tggcaaatct gttttattta gaagaatgat ccgtttcaat
    13681 ccacttgtcg cttccaataa ttgttcatct tctgctgtca gtggttcgct ttggtttaga
    13741 acaagtaaga tcaagtctgc ttctgctaat gcttttcggc ttctttcgac cccgatccgt
    13801 tccaccacat cttctgtttc ccgaattcca gctgtatcga ttagcttgag cggtaccccc
    13861 cgaacattga catactcttc gattacatct cgagtcgttc ctgcaatatc cgtaacgatt
    13921 gctttttctt ctcttaacaa atggtttaac aaacttgatt tgccgacatt tggccggccg
    13981 atgattgccg tacttaaccc ttcccgcaga accttccctt gcttggatgt agcaagtagc
    14041 gcttggattc tttgttggat catctgcgct ttttcaagca ataacttcgt agtcaattct
    14101 tcgacatcat catattctgg ataatcaata tttacttcta cttgtgctaa tgtctctaaa
    14161 atctcttgtc tcaatgagcg gatcaaagca gacagattgc cgtctaactg attaagagct
    14221 agtcccattg ctttgtctgt ttttgcccga atcaaatcca tcacagcttc tgcctgtgaa
    14281 aggtcaacac gaccattcaa gaatgctcgt tttgtgaatt cgcctggctc agctaatctt
    14341 gcaccttctc ttaacaatag ctgcaaaatt tgattgacta caacgatccc accgtgacaa
    14401 ttgatttcta ctacatcttc ccgcgtaaat gtctttggtg ctctcatcac ggagaccatg
    14461 acttcatcga caagctgatt gctcttggga tcaacgatat gtccataatg gatcgtatga
    14521 cttggtactt ctgataatcg tttgtttcca gattgataaa ctttatctgc tagttgcaca
    14581 gcttgatcgc cacttaaacg aacgatactg attgcacctt ctccaggtgg ggtagaaatt
    14641 gccgcaatcg tatcaaattc taaagtaatt tcagccattt tttcacttcc tttttcattt
    14701 tgcgcacaaa aaaagtgccc actccaccct ttatgcacaa taaacggtga acttcgcact
    14761 ttgactgctt gttcttgatt aaattctggt catagattat cacacttgct ataaggaatc
    14821 aagtgtttaa aacaattaga tgaagttgag cctgttctgc ttccattacc ttatatttaa
    14881 ttgtccttgg atgtctcttt gcgttctttg gtttattcga agagaagata ctgtataaac
    14941 aaggctttat ctttcttaaa aaaaacggta cactaaatgg tagcgctatc taaactatac
    15001 acttttgaaa ggagaaaata tgtgagcccg ttcagatctg ctgcattgga agaagaaagt
    15061 gaccctcgga tcaacgatgt cgttttatct acagggaata tcaaccagaa atatatcgtc
    15121 cgcgatatcg tttttgttgt ggaatgctta gaagctgatt tgtttgaccc atcttttccc
    15181 aaagatgacc ttttcttaac aacgaagagg aaattaaaga cgaaggtact tgaatatggt
    15241 gcgaatgcag taatcaactg tcattttgag tatcagcaaa aaaaacgcga cggaaagtat
    15301 tttctggaac tttttgctta tggaacagtg atccaattta tccaaacaac gattggttaa
    15361 atgaaacaga caaaaaaagc ggatcaaaac tgaagacagt ttcgatccgc ttttttctat
    15421 caaagttagt gactacttca tcgtatactc tgataagaat gatttctagt aaaatatact
    15481 tggtttgaaa aactttgtca acgtgattta ttcaaaaagt aatggaatca ataatatttt
    15541 ttagcaggtt ctactactaa ataacgataa ggttcctcac cttccgaatg tgtttttaca
    15601 tgttcatctt tgcttaatgc agcatggatt tgtttacgtt caaatgcagg cattggttct
    15661 aagaaaacag gctgccctgt ccgttttact ttttcagccg tgcgatcagc taaacgctga
    15721 atgatctctt ggcgcttttc acggtaattg cctacattga ctactacaga cagcttattt
    15781 cttgctaaac gatggatgaa gacttgtgcc agatattgca atgcattcag tgtttttcca
    15841 tgtttcccaa tcagtatgcc ttgcttttgt gtttctaaat ggaaaacaac catattattt
    15901 gattctcttt ccattttgac aagagctgga gcatcaagct gttttgaaat ttcagtaaga
    15961 taaactgcca attccgttaa agctgcttca tcacctagct cacttacttc ttctgttttt
    16021 tcttcaagaa tcgtttcgtt gactacctcg atctcagctg ttggttcttc ttccaaaatt
    16081 tcttctacag tctgttctac tgtttcagaa actttttcgc tgatacttgg ctggatcgaa
    16141 agccgtgcat tctttcgacc cattcctagg aaaccttttt ttccttcttc cagtatttcg
    16201 atttcgactt ggtctttggc caaacccaaa tcagccagac ctagttggac agcttcgtct
    16261 attgttgcag cttcataaat cggcattagc attacctccc ctattatttc cgttttttct
    16321 taggattcat tgctttctta agagcacgtt ctctttcgcg gattctccgt gcttcttctt
    16381 cacgctcttt tcgaattttg aaagggttgt tgatcagcag cgtttgtaca acttggaagg
    16441 cattggaaac tacccagtat aatgaaagac cgctggctaa attgacaccc atcactaaaa
    16501 tcattacagg catcacgaaa ttcatgatct tcattgatgc attcgattca atttgactca
    16561 tgctagataa atacgtactt gcaaaagtaa agattgctgc taaaatcggc aaaataaatg
    16621 ttggatccgc gttccctaag ttcaaccata agaaatgccc ttgtttcaac tctggtacac
    16681 gtgaaataga ttgccataac gccatcaaga ttggcatttg tactaataaa ggaagacaac
    16741 cagcatatgg attgacgcca ttttctgcat ataaacgctg ctgctcttct cttaacttac
    16801 tttgtgtttc cggatctctt gaactatatt gttgctgcag tgcttttaat ttcggttgta
    16861 attcttgcgt tttacgcatg ctctttgttt ggaaatgcat caacggcaat aggatcacgc
    16921 ggatgatcag tgtaaataaa atgatcccta tccctgcatt accaaatgac aacgccttga
    16981 tcgcctcagc aaagtaataa acaatataac gatcccaaat tcctgtactc tgtgcgctga
    17041 cttccccagt tccgcaaccg gataagacga tgaccaaact aacgataccg gccatcaaaa
    17101 gtaaacgttt gtatttcttc acttactctt ttcctctctg tcgattattt ttgcaagttt
    17161 taagacgtgg actaaattgg agcgaacctc atcataagtc aaccccttca cacttggtct
    17221 agcaatcaca ataaaatcca actccggatc aatttcttct tttatagaat aaactgctgc
    17281 tcggattttt cgtttgactt cattgcggtt taccgcgttg ccgacctttt ttcctacaga
    17341 taaaccaact cgaaaatgag gctgtcccgg tttttccaaa cggtaaacga cgaatttgcg
    17401 gttagcaaaa gaatctcccg tatggaacac ggcttgaaac tctcgttctt tttttactcg
    17461 atacgctttt ctcattagtt ttctttcctt ttctatctct cacttacgct cataatcata
    17521 ccataattac gattgtcctt tcatcatttc cctaaaaaag agtataaaaa aaaccactga
    17581 aaccccagtg gcctaagctg aaagaacttt tcttcctttg cgacgacggc tagctaacac
    17641 acgacgtcca tttttagtac tcatacgttt acggaatccg tgaacttttt gacgtttacg
    17701 tttatttggt tggtatgttc ttttcatata ttccacctcc aaaatgttct tatctatttt
    17761 ataaacacag acatactttg atagtataac gacaaagtag tgattttgtc aatataaaat
    17821 agaagatcga ttgttaaaac ttatccacaa gattattttt ttctatggga atcctatgtg
    17881 gaaaaagtta tgcacaggga ttatccacag ataataaaag gctggtttta cacagaaaac
    17941 acacgtgtaa aaaaagtaat ccacaatcag gcgatttcct gtgtattccg tctcctaact
    18001 attggtatat ctgtattttt tatccacaga cgcaagagga aatctattgg tttttacgag
    18061 ttttccacct gtgcattagt ggtgtggaaa actttttttg acaactgtgt ttttctcttt
    18121 tttctttttg tcgattgtgt ggataattgt aattaaaaaa tttttttctt cggtttctgt
    18181 ggaaaactat tgaaaaaaat gctaaattag tactagttat tcacttttta atgaaggagg
    18241 aggccttata tggtatccct cgatgcttta tggaatgaat taaaagcaac ataccaaaag
    18301 gatttatcgc ctgctagcta taatacatgg atcgaaacag cgaaccctcg aacccttgat
    18361 caaaaccagc tcgttgttga ggttcctagc aagattcata aagaatattg ggaaaaaaac
    18421 ctggcgacaa aaatcgttga agtcggttat atgttatcag gaaatgagat tatccctcgc
    18481 tttattactg gcgaagaagc agagcaagaa gaagttatag aagaaaaaaa tccaaaagtt
    18541 gtggcaccta gtccgctaaa aaaagccatg ctgaacccta aatatacctt tgatacgttt
    18601 gtcattggta aaggaaacca gatggctcat gcagcagcgc tcgttgtagc agaagatcca
    18661 ggttctattt ataacccgct cttcttttat ggaggcgtgg gacttggtaa gactcacttg
    18721 atgcatgcaa ttggtcatca aatgctgcaa agtcagccta atgccaaagt aaaatatgta
    18781 agcagtgaaa cttttgctaa tgatttcatc aattcgatcc aaaacaaaac agcagaagag
    18841 ttccgtcaag aatatcgaaa tgttgattta ctgctagtgg atgacattca attttttgca
    18901 gaaaaagaag ctacgcaaga agagtttttc catactttca atgccttgta caatgaaggg
    18961 aaacaaatcg tactaaccag tgatcggttg ccaaacgaga ttccgaaact gcaagaacgc
    19021 cttgtttctc gctttgcatg ggggctgtct gttgatatta caccgccgga tcttgaaaca
    19081 agaacagcga ttttacgtaa aaaagcggcg gctgaacgtc tagagatccc agatgacaca
    19141 ctaagctaca tcgcaggaca aattgattct aacattcgtg aattagaagg tgcgcttgtt
    19201 cgagtgcaag cttttgctgc gatgaatagt gaagatattt cgactagtct agctgcagac
    19261 gcactgaaaa cgttaaaatc aggaaaagga catcctcaat tgtcaatcct gcagatccaa
    19321 gaagaagtgg caaagtatta tcacatccaa ttgaaagatc tcaaaggaaa gaaacgcgtc
    19381 aaatctattg ttgttcctag acaaatcgct atgtatttgg cacgtgagct cacagataat
    19441 tctttaccga aaatcggagc tgaattcggt ggcaaggatc atacaacggt tatccatgct
    19501 catgaaaaaa tccagcagct gatggattct agtgtcagta tgcaaaatga agtatcagaa
    19561 atcaaaaact ttttactaaa ttaatttgtc gattctatca actgaaaata gcatgtggat
    19621 aaaagaaaaa aacgttcaaa agttatacac actttttcca cagctgtttt ttcgtttctc
    19681 tcttacgttt tttgagtttt ccacagaatc aacatgccct attactttta ttattctttt
    19741 taactaataa taaataaaca aacattcaaa ggagatacat catgaaagtt actttaaacc
    19801 gagctagctt tatgcaggaa ttgcaaactg ttcaacgagc tatttcaagc aaaaccacga
    19861 tccctatttt gacaggtgta aaaatcacac tgacacaaga aggtttgact ttgacgggga
    19921 gcaacgctga tatatcaatt gaaacttttt tgtctgttga aaacgaaaaa gcaaatatgc
    19981 aaatcgaatc tactggttcc attgttttac aagcacgttt ctttagcgaa atcattcgga
    20041 gacttcctga agaaacattt actttagaag ttttagaaaa taaacaagta gcgatcactt
    20101 ctggaaaagc gaattttatc gtaaatggat tagatgcaga taactatcct catcttcctg
    20161 ttgtcgaaag ccataaccag atgaaattac ctgtacacgt attgactaaa ctaatcaacg
    20221 aaacagtttt tgctgtctca caacatgaga gtcgtccaat cttgacaggt gtgcatttca
    20281 ttttatctga taattcttta ttagctgtag ctactgattc tcaccgtcta agtcaacgcg
    20341 tgattccagt agaacaagcg gctgatcatt ttgatattgt tattcctgga aaaagtttga
    20401 tcgaattatc tcgctcatta acaaatgaag aagaaatcgt cgaaatcagc attatggaaa
    20461 accaagtgtt gttcaaaaca gaaacgatgt atttctattc ccgtttgcta gaaggaaact
    20521 atccagatac caatcgtttg attccttcaa gttttaatac agaggttgaa ttttctgttc
    20581 ctagcttttt agcggcgatc gaacgggctt ctttactttc tcatgaaggc cgtaacaaca
    20641 tcgttcgttt atctattcgt ccagatgcgg ttgttttata cggaaattcg ccagaaatcg
    20701 ggaaagtaga agaaagcttg agttatacag caagcagtgg cgatccatta gatatttctt
    20761 tcaatccgga ttatatgaaa gcagcgttgc gtgcatttgg agatatgagc atcaaagtga
    20821 aatttatctc tgctattcgt ccatttacat tggaaccaac ggaagatggc gttcaattta
    20881 ttcagctgat tactcctgta cgtacaaatt aacaatgatt ttcaatgttc ttgaaaattt
    20941 aattgaaaag aaatagaaaa aataaaattt taaacagaag gccctaaaat ctcttttaag
    21001 gctttctgtt tatttttgtt taaatcacct tttttagatt aaatcgtctt atatggaaaa
    21061 atatatggat aaatttgttt tattgcgaaa aaaaaggtat aatagagtat acttttaata
    21121 atgaaaatga gggatgggca ttgaaacaac aagtcattct aaatacggaa ttcatgacgt
    21181 tgggccaaat gttgaaagaa gtcacagtta tcggtagtgg cggacaagca aaatggtatt
    21241 tggcagaaaa cactgtgtta gtcgatggcg aaccagaaaa tcgtcgtgga cgcaaacttt
    21301 atcccggcat gatggttgaa gttccagaag taggaacttt ttttatggta aaaaaaggaa
    21361 acgacgataa tgaggctgaa taagctgtat ttaaaaaatt atcgaaatta cgaagagctg
    21421 aacatcgaat tttccaagaa cctcgtcatc tttttaggag aaaatgcgca aggaaaaacg
    21481 aatcttttgg aaagtatcta cgtattagct atgacgcgaa gtcatcggac aagtagtgag
    21541 caggaattga ttggctggac tgacgatcag gcgatgattc aaggagagat cacaaaaggt
    21601 tcatccactc ttccattaga aatcttatta tctaaaaaag gccgaaaaac caagatcaac
    21661 catatcgaac agaaaaagtt aagtacttac gtgggacaaa tgaatgtcat tttatttgca
    21721 ccagaagatc tttctttagt aaaaggcagc ccgcagatca ggcggaagtt tttagatatg
    21781 gaattaggcc agatcaatcc aatctatctt tatgatcttg tccaatacca agcaattttg
    21841 aaacaaagaa accagtactt gaagcaattg aatgaaaaaa aacaaactga tttgctttat
    21901 ttggatattt tgtccgaaca actagcagcg tttggcagca aagtattgaa agcaagagca
    21961 cagttcgtca agcgattgga gttttgggct aattctttgc atcagcaaat cacccatcaa
    22021 aaagagcagc tggaaatcga gtatctcacc gcagtcgatt ctttagaaac acatacgcaa
    22081 gagcaaatcc aagaacaatt tctcgcactt ttgaaccaaa ataaaaagaa agaccttttt
    22141 cggggaacaa cgacagttgg tcctcatcgt gacgatcttt ccttttttat taatcagaaa
    22201 aatgtgcaga cttatggatc gcaaggacag caaagaacaa ctgcactaag tgtcaaatta
    22261 gcagaaatcg atttgattaa agaagagaca ggggaatatc caatcctttt gttagatgat
    22321 gtgatgagcg agctggatga taatcgtcaa ctccatctgc tagaaacaat cgaaggaaaa
    22381 gttcaaacgt tcttaacaac aacgacactt gaccatgtaa aaaataaaat gactgttgaa
    22441 cctgagattt tttatgttca acaagggaaa ctaaaaggag aagaaactga atgacagaag
    22501 aaagaagttt agtagaacgc gctaaagagt atgatgccag tcagattcaa gtacttgaag
    22561 gacttgaagc cgttcgtaaa cgacctggca tgtatatcgg ttcgactagt tctgagggtc
    22621 tgcatcacct tgtttgggaa attgtcgata attcgatcga tgaagtatta gcaggttttg
    22681 caacgaaaat ccatgtgatt attgaaaaag acaacagtat caccgttatt gacgacggtc
    22741 gggggatacc tgtagatatc caggcaaaaa ctggacgtcc tgcagttgaa acggtcttta
    22801 ctgttttaca tgctggagga aaattcggcg gtggtgggta caaagtttct ggtggacttc
    22861 acggagtagg atcttctgtt gtaaacgcgc tttctacaca gcttgatgtc aaagtataca
    22921 aagaaggaaa tgtgtactat caagaatatc gtcgtggagc tgtagtggac gacttaaaga
    22981 ttatcgaaca aacggatcgc catggaacaa cggttcactt tacgccagac cctgaaattt
    23041 ttacagagac aactgagttt gatttttcaa aattggctac ccggatccgt gaacttgctt
    23101 tcttgaaccg cgggatgcgt atatcgattg aagacaaacg agaagaagaa ccagtcatca
    23161 atgaatacca ttatgacggc gggatcaaaa gttatgtcga atacttgaat gcaaacaaaa
    23221 ccgtgatttt tccagaacct gtatatttgg aaggtgaaca gcaagatatc gcagttgaag
    23281 tctctatgca atatacagac ggctaccatt ccaatatcat gagttttgcc aacaatatcc
    23341 atacgtatga aggtggaaca catgaatcag gattcaagac tgctttaact cgtgtgataa
    23401 atgattatgc ccgaaaacaa aagctgatga aagaaaatga cgacaacttg accggtgaag
    23461 acgtgcgaga aggattgaca gctgttattt ctatcaagca tcctgaccct caattcgaag
    23521 gacaaacaaa aacaaaattg ggcaattccg aagtacggac agtcactgat cggttattta
    23581 gcgaacattt catgaaattc ttgctggaaa acccaagtgt gggccggcaa attgttgaaa
    23641 aaggattact agcttccaga gctcgtctag cagcgaaacg tgcgcgtgaa gtaacgagac
    23701 gtaaaggtgc tttagagatt agtaatctgc caggaaaatt agcggactgc tctagcaacg
    23761 atcctgaaaa atgcgaattg ttcatcgtcg aaggagattc ggccggcgga tcagctaagc
    23821 aaggtcgtaa tcgagagttt caagccatct tgcctattcg tgggaaaatc ttgaatgttg
    23881 aaaaagcaag catggacaag atcttggcaa atgaagagat ccggtcttta tttactgcta
    23941 tgggtacagg gtttggagaa gattttgatg tatcgaaagc tcgctaccac aaattagtta
    24001 tcatgactga tgccgatgtc gacggcgcgc atatccgtac attgctgctg actctttttt
    24061 atcgttacat gcgtcctatt gttgaagctg gatacgtcta tattgctcag ccacctttat
    24121 acggggtaaa acaagggaag aatattacgt atgtacaacc aggaaaaaat gcagaagaag
    24181 agttgaaaca agtcgttgct tcacttcctg cctcaccaaa accaagcgtt cagcgttata
    24241 aaggacttgg agaaatggat gatcatcaac tatgggaaac aactatggac ccaagcaatc
    24301 ggatgatggc ccgcgtcagt gtggacgatg ctattgcagc agatcagata tttgaaatgt
    24361 tgatggggga tcgagtagaa ccccgtcgtg cattcatcga ggaaaatgca cactatgtga
    24421 agaacttaga tatttaatca tgaaggagga aaaagaatga gtgaagaaat cagagaaaac
    24481 atccatgatg tcaatctaac cagcgaaatg aaagactcct tcatcgatta tgcgatgagt
    24541 gttattgtcg cacgtgcact tcctgatgtc agagatggtc tgaaacccgt tcatcgccgt
    24601 attttatacg gcatgaacga attaggtgta acaccggata aagcccataa aaaatctgcc
    24661 agaatcgtcg gagatgtcat gggtaaatac catcctcatg gagacattgc gatctatgag
    24721 tcaatggtac ggatggcaca gccattcagc taccgttata tgctagtgga tggtcatgga
    24781 aactttggtt ctgttgacgg tgacggtgcc gccgctatgc gttataccga agcacggatg
    24841 agcaaaatcg ctacagaaat gctgcgtgat atcaataaga acactgttga tttccaaagc
    24901 aactatgatg atacagaaaa agaaccagtt gtactacctg ctcgcttccc gaatctttta
    24961 gtgaacggaa caacggggat cgccgtaggt atggccacga atatcccacc tcataacttg
    25021 tctgaggtag tagcggctat cgatttgctg atggataatc ctgatgtgac gaccaatgaa
    25081 ttgatggaag tattacctgg accagatttt ccaacaggtg gtttggttat ggggaaatca
    25141 ggaatccgaa gagcgtatga aacaggtaag ggttctatta ccgtacgtgc aaaagttgag
    25201 attactgaga tgccaaatgg taaagaacgg atcatcgtga cagaattgcc ttatatggtc
    25261 aataaagcaa aattgatcga acggatttct gaactgcaca gagacaagcg tatcgaaggg
    25321 atcacagatt tgcgggacga atcttcccgt gaaggtatgc ggatcgtcat tgacatccgt
    25381 cgtgacgcca gcgcatccgt tatcttgaat aacttatata aattgacatc cttgcaaaat
    25441 tcatttggat tcaatatgtt ggcgatcgaa aaaggtgtgc cgaaagtttt gagcttgaaa
    25501 caaatccttg aaaactatat cgaacatcaa cgcgaagtca tcacacgacg gacggtcttt
    25561 gaaaaagaaa aagcagaagc aagagcacac atcttagaag gtttgcgtat tgctttggat
    25621 catatcgatg aaatcattgc gattatccgc gggtctaaat cagatgacga ggcaaaagca
    25681 acaatgatcg aacggttcga tttatccgat cgccagtctc aagctatttt agatatgcgt
    25741 ttacgccgat tgaccggttt ggaacgggaa aaaatcgaaa atgaatacca agaactctta
    25801 aaactgattg aagatttaac tgacattctg gcaagaccag aacgtgttac agaaatcatc
    25861 aagaatgaat tagcagactt gaatcaacga tttggtgata aacgacgcac agaattacta
    25921 gtcggtgagg tcttaagtct ggaagatgaa gatttaatcg aagaagaaga aatcgttatt
    25981 acattgacaa acaatggtta catcaaacgt ttggcaaata atgaattcag agctcaacga
    26041 aggggtggac gtggtgtcca aggaatgggt atccacaatg acgacttcgt caaaaatctg
    26101 gtttcttgtt ctacccatga tacattgtta ttctttacga ataacggaaa agtgtatcgg
    26161 gcaaaaggat acgaaattcc agaatacggg cgtacagcca aaggaatccc aatcatcaat
    26221 ttactaggta tcgattcgag tgaaagcatc caggcaatca ttgcggtgac gggagaagca
    26281 gaagaaggcc actatctctt ctttacgacg cgtcaaggta cagtaaaacg tacttctgtc
    26341 actgcttttg ctaacatccg aagtaatggt ctgatcgcaa ttggtttgaa agaagacgat
    26401 gagctcgtca atgtgctact gacagatggt caatctaata tcattattgg aacacataac
    26461 ggctactctg tcactttcaa agaagaagca gtccgcgata tgggacgtac agcttccggg
    26521 gtcagaggga tacgcctgcg tgaggaagat tatgtcgttg gggcagcctt aatgaaggaa
    26581 aatcaagaag tattagtgat cacagaaaaa ggttacggaa aacggacaaa agtatcggaa
    26641 tatccagtga aaggccgcgg aggtaaaggg atcaaaacgg cgaacatcac tgaaaaaaat
    26701 ggtccactag ctggattgac cactgtttct ggagatgaag acatcatgct gattacagat
    26761 aaaggtgtca ttatccgttt caacgtatcg actgtttctc aaactggacg ttcaacatta
    26821 ggcgtacgtt tgatgaagat ggaagctgat acgaaagttg tcacgatggc agcagtcgaa
    26881 ccagaagctg cagaacaaac agttgaagaa caaggatcag aagaataacc atcaagacta
    26941 agtgtgtaag ctagcaagaa taaccgatta aaaaatctgg ttattcctgc tggctttttt
    27001 gattagttga atttctctta aaatattcga aactgttcat tctgtattgc ttttgaccaa
    27061 aatagagtgt ataattagag cttgtgagta gtctaattaa ttagataact ctccttgctc
    27121 ttaggaacct aagagccgaa agtccacagg gaggtgaata tcaatggaaa acacgaaata
    27181 tgaaatcatg tacattattc gtccaaacat tgatgaagaa gcaaaaactg ctttaatcga
    27241 acgtttcgat gcaatcttga aagataacgg agcagaagtt atcgaatcaa aagattggga
    27301 aaaacgccgt ttcgcttatg aaatgaacgg ttaccgtgaa ggtatctatc acatcgttaa
    27361 agtatcttct ccatcatcag caaatgctgt caatgaattt gaccgtcttg ctaaaatcaa
    27421 cgacgatatc attcgtcaca tgattgttaa agaagaagct taattgttgt ttcatgtgaa
    27481 acaatagaaa acgatgagag gagatgacta ttttgattaa taatgttgta ttagttggac
    27541 gtctgacgaa agatccagat ttgcgttaca cagcaagtgg tacggcagtc gcaacattta
    27601 ctttggctgt gaatcgtaat tttacaaacc aaagcggcaa tcgcgaggct gattttatca
    27661 actgtgtgat ttggcgcaaa tcagcagaaa ctttagcaaa ctatgctcgt aaaggaacac
    27721 ttttaggtgt tactggacgt atccaaactc gttcttatga taatcagcaa ggacaacgtg
    27781 tatacgtgac agaagtagta gctgacaact tccaattgct ggaaagtcgt tctgcatctg
    27841 aaaatcgcca acaaagcggc ggattccaaa gttctggtca atcagctggc ggatttggcg
    27901 gaaacaataa ctctaatcaa acatctcaat catccaacgg tatgcctgat ttcgaccgtg
    27961 atacttctga cccattcggc tcaagttcaa cgatcgacat ttcagacgat gatttaccat
    28021 tctaaacgaa tttgatagga gggaaataga atggcacaac aaagaagagg cggacgtaaa
    28081 cgtcgtaaag tagactacat tgctgctaac catattgaat atatcgatta taaagatatc
    28141 gaattactaa aaagatttat ttcagaacgc ggtaaaatct tgccacgtcg tgtaactggt
    28201 acaggcgcta aaaaccaacg taaaattact gttgcaatca aacgcgctcg tatcatgggc
    28261 ttgctacctt tcgttagcga agactaataa atcctaggaa ttgaatgact gatccttttg
    28321 atcagctatt caattccttt ttttctgtaa aaataacctc tattcgttta gtcgctcgaa
    28381 tgacgaaagt tatggtaaaa tcaaattagt catatatggg aggaaaatta tggaaaataa
    28441 aaacaatcat ttatccccga aacctctctt ccttatcctg tttatattaa tcgaagtatt
    28501 ggtagtctta attttaccat ttcgttttgt tagcgcttcg gtcattctat tgatgaattt
    28561 atggggtgtt cgctattggt tgaaaatgaa acgttggctt attttaaata aacgtgaaaa
    28621 aatccagcag gcttcgactg tagctgaaac caatctagct tatgtctcag aagtcatgcc
    28681 tgtaggagtg attgcttatc agccatcaag ccaaaaaatc gaatggctca atccattagc
    28741 attgaaaatc aaagatcaaa gtggattaac agaggaagaa ttgctagata ctttttttac
    28801 tgcaaaagaa aaaaagaaaa accaagtcta tctagcagat aaaacatttc agtttgatat
    28861 ggatacagta aagggtgttg tttattttaa tgatattacc caaaaccagt tgttaaaact
    28921 ccatcagacg aacagtcagc cggtgattgg tattttatct attgataact atgcagatgc
    28981 cattgataaa ttagatgaca aagagatttc ttatttgaac tctttcgtca ctacactagt
    29041 ttctgactgg atgaatgaat accatgtctt tttcaaaaga atcaacgcag aacggttttt
    29101 cttcgtagca cagatgatcg atctgaaaaa gatgatggat aaaaaatttg atttgctgga
    29161 tcgctttcga gcagaagctg aaaaacagag ctcgcctatc acccttagta tggggattgc
    29221 ttatggctca agaaccctcg atgaaatcgg tggagaagct cagaataatt tagatgttgc
    29281 tttagtccgt ggaggcgacc aagttgtcgt gaaagaggta aaagaaggag caaaacctgt
    29341 ttattatggg gggaaatctg ctaagaatgt caaacgcacg cgtgttcgtt ctcgagcgat
    29401 gagtaccgct ttgcgtcgga tttttgatga aacaggcgat gtgtttatca tggggcacaa
    29461 gtttccggat atggatgctt taggctctgc ttttggtgtc agttgtctgg cacgcttcaa
    29521 ccagaaaaaa gcttacatcg ttatcaatga gaacgagatc attccagatg tagaacggtg
    29581 tcttgaagaa atccataagc atcctgaatt agaaatgcaa ctaatctctc cagaacgtgc
    29641 catagagctg aaaaaagaag aggacctcct cgtgatggtg gattaccata aaccttctct
    29701 atcgatctct cagggcctat atgagcaatt tgataagatt gtgatcattg atcaccatcg
    29761 tcgtggggaa gagtttccaa gtaaacctct gctgacttat attgaatctt cagcttcttc
    29821 agcttcagag ctagtttctg agctgatcca ataccaaagc agcaaaacaa atcgcttaga
    29881 tcgttttgag gccacattat tgcttgcagg gatggttgta gatacaaata gtttcaatgt
    29941 ccgtacaact gcacgaactt ttgacgttgc cagctattta aggtcttgtg gagcagacgc
    30001 atccttagta caatatttat tgagctcgga tttagcgaca tacttggaga tcagcaattt
    30061 gattgctgga agcgactatg tgacttctga tattgttgtg gcggcaggga cagacgaaaa
    30121 agagtataat agtgttatag cagcaaaaac agcagataca ttgctttcga tgatcaatat
    30181 caatgcagct ttcgtcatta caaagcggac agacggcttg attgggatca gtgccagaag
    30241 taccggcacg atcaacgtcc aaatcatcat ggaatcctta ggtggcggag gacacttcac
    30301 aaacgcagct actcaactgg aaaatacgac agttgaggaa acaaaacaga agctatttgc
    30361 tgcaatcaaa gaaaatatga atcaaatata tgataaggag taatccaaat gaaagtaatt
    30421 tttttacaag atgtaaaagg aaaaggtaaa aaaggggaca tcaaagaagt tccagcaggt
    30481 tatgcacaaa attatctaat caaaaataac ttggcaaaag aagcaacgaa aagcagtatc
    30541 agtcagttag caggacaaaa gaaagcacaa gaaaaacacg aagctgaaat cttggaagaa
    30601 gctaaaaagt taaaagaatt cttggaaaaa gaagatactg tagtcgaatt gaaggcgaaa
    30661 gcaggggaag acagccgttt gtttggttcg atcccttcaa aacaaattgc tgaagggtta
    30721 aacaaacaat acaaaatcaa attagataaa cgaaaaatcg aattagaaaa tccgatccgt
    30781 tcactaggct acacaaacgt acctgttaag cttcatcatg aggtgacggc tacgatcaaa
    30841 gttcatgtcg tacaagaata acaaatcttg atagcgatgt tcagctggta agtataacca
    30901 gaaggaaaaa agacaaaccg aaatttatct gagaaaacag ctgcagcaat gaaagcaaaa
    30961 gctgcaaatc gatttcagat tgatttcggt ttcttttttg ggaacagcaa aatagcataa
    31021 agaaaacgag tataataaaa gagaactatt tttttattac actttcggta cgaatgatga
    31081 cttttctctc attttcttgt aaaatgaagc aattgaagac aaggagcgat acgtatgaat
    31141 gaagtgtggc aggatcgaat cccaccgcaa aatattgaag ctgaacaagc ggttttaggc
    31201 tctgtttttc ttgacgcaga aacgatcatt gatgccatgg agtacataga gccaaaagac
    31261 ttttatcgtc gtggccatca aattattttt gagacaatga tcgagttaaa tgatcgtaat
    31321 gaagcgattg acgtggttac tgtcaaagac cggctggaac aagccaattt gttagaagat
    31381 gccggtggtt taagttatct ctcagacttg gcattagcag ttccgacagc agcaaatatc
    31441 gtctactatg cgaaaatcgt tgaagaaaaa tcattgctgc gtacattgat ccagacagca
    31501 acaggaatcg ttacgaaagg attcgagcaa ggagaagaag ttcaaacaat tttagatgat
    31561 gccgaacgca gtatcttgga ggtttcggaa aaaagaaatc gaagcggctt tttatctatt
    31621 gctgaagtac tgaactccac gattgaaaat atcgatcgac tagctcaaaa caatgaagaa
    31681 atcacaggtc taccaactgg ctatcaaggt ctggataaaa tgacagcagg tttccagccc
    31741 gaagaactaa tcattcttgc tgcacgtcca gcggtaggta aaacagcgtt tgcattgaat
    31801 attgctcaaa atgtaggaac aaaaacagat cgttctgttg cgatatttag tttggaaatg
    31861 ggggcagaat ctcttgtaaa tcggatgctt tgtgcagaag gttcgattga ggccagccat
    31921 ttacgtacag gtcagctttc ggaagaagaa tggtcgaatc tgatcgttgc gatggggagt
    31981 ctttctcgag caaatatttt tatcgatgat acaccaggga tcaaaatctc tgaaatccgt
    32041 gcgaaatgtc ggaaactagc gcaagaaaaa ggcaatctag gcttgatatt gatcgattat
    32101 ttgcagttga ttgaaggtaa cggtaaagag aaccgtcaac aagaagtatc agatatctct
    32161 cgccaactga aaaaactggc gaaagagctg aaagtacctg tcattgctct ttcacagtta
    32221 tctcgtggag tagaacagcg acaagacaaa cgaccagtgc taagtgatat tcgtgaatcc
    32281 ggatcaattg aacaagatgc ggacatcgta gccttcttgt atcgagatga ttattatgaa
    32341 agagaaggcg gagatgacga tgatggaaac gagccaaaaa atgacaacgt catcgaagtc
    32401 atcatcgaga agaaccgaag cggtgcacga ggaacagttg aactactgtt tatcaaagaa
    32461 tacaataagt tttcgtcgct ttcgccaaga gaagaatttt aaagaagagg ttgtgagcct
    32521 tgagcaatcc cgagagctct cgtaagaaga tgcaaggagt aaccgcagga acgactagag
    32581 tacttaattt aaacagatct ccaaagggat tgtgacaaaa gtcttgtcac agtccctttt
    32641 tccgaataaa cggtgttcaa tcagctgacc cttggtatta gctcagcaaa cgtcaaaata
    32701 tgaggaacta ttttgacgtt tgtttctcta atactcaggt caaaacgctg atcttacgac
    32761 ctcttttcct taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatcatca
    32821 aacatgagaa gcagtttttt gaaattgctc cttgtgactc agagttaaac ggcaggctca
    32881 caacctcttt cttaaacggt gttcaaaagc ttgcatctgc ggtaatacgc ccaatcaaac
    32941 gaaaaatatg agaagctatt tttgtttggc tgttcttatt acttgatgca ggacagcttt
    33001 ttcacaacct ctgattcacg gtgttccaaa agtagcttct tcgaaaaata agtcgaaatt
    33061 tcacaaaaat ttgagaagca attttcgtac attccttctt atttcttgaa gctgaccact
    33121 tctgttacaa cctctttttt aataaccatt ctaaaaagat aaagttcgtt ttttaagcgt
    33181 ttttataaaa taaaaataaa aatcattcga ttttatttga aatatgtatc tattattgat
    33241 acaatggttc aggattaaat aatatagaac gaggtgttca catgtcatct gtagtagtag
    33301 taggtacgca atggggcgat gaagggaaag gaaaaatcac agactttctc agtgaaaatg
    33361 ctgaagtgat tgcacggtac caaggtggcg acaatgcagg gcacacaatt aagtttaacg
    33421 gtgtgactta taaactgcat ttgattcctt ctgggatttt ttataaagac aagatcagtg
    33481 tgatcggaaa cggcgttgta gtcaatccta aatcattggt taaagaatta gcttatttac
    33541 atgaaaaagg tgtagaaaca agtaatttgc gtatttctga ccgcgcgcac gtaatcttgc
    33601 cttatcatat caaattggac caattacaag aagatgctaa gggcgaaaat aagattggta
    33661 caacgattaa aggaatcgga cctgcctata tggataaagc agctcgtgta ggtatccgta
    33721 ttgcagactt attagataaa gaaatttttg aagaacgtct tcgtttgaat ctagatgaca
    33781 aaaaccgtca atttgtaaaa atgtttgatt cagaaccact tgattttgac gatatttttg
    33841 aagaatatta tgaatacgga caacaaatca aacaatacgt cacagatact tccgttatct
    33901 tgaatgatgc tttggatgca ggcaaacgcg tgttgtttga aggcgcacaa ggtgtaatgc
    33961 tggatatcga ccagggaact tatccttttg ttacttcttc taacccagta gccggtgggg
    34021 taacaatcgg aagcggtgta gggccttcaa aaatcaataa agttgtcggc gtctgcaaag
    34081 cctatacgtc acgtgtcggt gatggaccat ttccaactga attatttgat gaaacaggag
    34141 aacaaatccg cgaagtagga cgagaatacg gtacgacaac tggtcgtccg cgtcgtgtag
    34201 gctggtttga ttctgtagtt atgcgccatt ctaaacgagt ttcaggtatt accaacctat
    34261 ctttaaactc gatcgatgta ttaagtggat tggaaacagt aaaaatttgt acggcttatg
    34321 aattagatgg cgaactaatc taccactatc cagcaagctt gaaagagttg aaccgctgca
    34381 aaccaatcta tgaagaattg ccaggctggt cagaagacat tacaggatgc aaaacacttg
    34441 cagaactgcc agaaaacgca cgtaactatg tacgtcgtat ctcagagctt gttggtgtac
    34501 gtatctcaac attttctgtc ggacctgata gaacacaaac aaacatctta gaaagcgtct
    34561 gggcgcaaat ctaaggataa aaacgacgac tgaatcagga cgttcttacc agagcgagtc
    34621 gaagtgttta tctatacgat aataataact tgaagaggta gtgaaagaga cgtttagcct
    34681 tattgccgat aggctgtctc ttgaacactg tttattcaga ataagggact gtgacaaaaa
    34741 ccgtgtcaca gtcccttttt ccgaa
//
LOCUS       DAZKCW010000028        34603 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000028 DAZKCW010000000
VERSION     DAZKCW010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.028"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(47..895)
                     /locus_tag="ACG84Z_001508"
     CDS             complement(47..895)
                     /locus_tag="ACG84Z_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFP9162359.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1119..3059)
                     /gene="thrS"
                     /locus_tag="ACG84Z_001509"
     CDS             complement(1119..3059)
                     /gene="thrS"
                     /locus_tag="ACG84Z_001509"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFP9162360.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3396..3575)
                     /locus_tag="ACG84Z_001510"
     CDS             complement(3396..3575)
                     /locus_tag="ACG84Z_001510"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFP9162361.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3622..5445)
                     /locus_tag="ACG84Z_001511"
     CDS             complement(3622..5445)
                     /locus_tag="ACG84Z_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9162362.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5723..8002
                     /gene="helD"
                     /locus_tag="ACG84Z_001512"
     CDS             5723..8002
                     /gene="helD"
                     /locus_tag="ACG84Z_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFP9162363.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8095..8742)
                     /locus_tag="ACG84Z_001513"
     CDS             complement(8095..8742)
                     /locus_tag="ACG84Z_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162364.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8921..9640)
                     /locus_tag="ACG84Z_001514"
     CDS             complement(8921..9640)
                     /locus_tag="ACG84Z_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9162365.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9771..10922)
                     /locus_tag="ACG84Z_001515"
     CDS             complement(9771..10922)
                     /locus_tag="ACG84Z_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFP9162366.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11139..11879)
                     /locus_tag="ACG84Z_001516"
     CDS             complement(11139..11879)
                     /locus_tag="ACG84Z_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9162367.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11883..12206)
                     /gene="rsfS"
                     /locus_tag="ACG84Z_001517"
     CDS             complement(11883..12206)
                     /gene="rsfS"
                     /locus_tag="ACG84Z_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFP9162368.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12263..12856)
                     /gene="yqeK"
                     /locus_tag="ACG84Z_001518"
     CDS             complement(12263..12856)
                     /gene="yqeK"
                     /locus_tag="ACG84Z_001518"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFP9162369.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12840..13490)
                     /locus_tag="ACG84Z_001519"
     CDS             complement(12840..13490)
                     /locus_tag="ACG84Z_001519"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFP9162370.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13500..13811)
                     /gene="yhbY"
                     /locus_tag="ACG84Z_001520"
     CDS             complement(13500..13811)
                     /gene="yhbY"
                     /locus_tag="ACG84Z_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFP9162371.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13827..14936)
                     /gene="yqeH"
                     /locus_tag="ACG84Z_001521"
     CDS             complement(13827..14936)
                     /gene="yqeH"
                     /locus_tag="ACG84Z_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFP9162372.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14933..15460)
                     /locus_tag="ACG84Z_001522"
     CDS             complement(14933..15460)
                     /locus_tag="ACG84Z_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFP9162373.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15640..16425)
                     /locus_tag="ACG84Z_001523"
     CDS             complement(15640..16425)
                     /locus_tag="ACG84Z_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFP9162374.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16418..17287)
                     /gene="accD"
                     /locus_tag="ACG84Z_001524"
     CDS             complement(16418..17287)
                     /gene="accD"
                     /locus_tag="ACG84Z_001524"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFP9162375.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17288..18667)
                     /locus_tag="ACG84Z_001525"
     CDS             complement(17288..18667)
                     /locus_tag="ACG84Z_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFP9162376.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18675..19094)
                     /gene="fabZ"
                     /locus_tag="ACG84Z_001526"
     CDS             complement(18675..19094)
                     /gene="fabZ"
                     /locus_tag="ACG84Z_001526"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFP9162377.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19119..19595)
                     /gene="accB"
                     /locus_tag="ACG84Z_001527"
     CDS             complement(19119..19595)
                     /gene="accB"
                     /locus_tag="ACG84Z_001527"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFP9162378.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19598..20833)
                     /gene="fabF"
                     /locus_tag="ACG84Z_001528"
     CDS             complement(19598..20833)
                     /gene="fabF"
                     /locus_tag="ACG84Z_001528"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFP9162379.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20852..21589)
                     /gene="fabG"
                     /locus_tag="ACG84Z_001529"
     CDS             complement(20852..21589)
                     /gene="fabG"
                     /locus_tag="ACG84Z_001529"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFP9162380.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21601..22518)
                     /gene="fabD"
                     /locus_tag="ACG84Z_001530"
     CDS             complement(21601..22518)
                     /gene="fabD"
                     /locus_tag="ACG84Z_001530"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFP9162381.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22625..22849)
                     /locus_tag="ACG84Z_001531"
     CDS             complement(22625..22849)
                     /locus_tag="ACG84Z_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFP9162382.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22902..23864)
                     /locus_tag="ACG84Z_001532"
     CDS             complement(22902..23864)
                     /locus_tag="ACG84Z_001532"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFP9162383.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23874..24314)
                     /locus_tag="ACG84Z_001533"
     CDS             complement(23874..24314)
                     /locus_tag="ACG84Z_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9162384.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24620..25585
                     /locus_tag="ACG84Z_001534"
     CDS             24620..25585
                     /locus_tag="ACG84Z_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFP9162385.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25642..25872)
                     /locus_tag="ACG84Z_001535"
     CDS             complement(25642..25872)
                     /locus_tag="ACG84Z_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFP9162386.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25958..26845)
                     /locus_tag="ACG84Z_001536"
     CDS             complement(25958..26845)
                     /locus_tag="ACG84Z_001536"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFP9162387.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26934..28157)
                     /locus_tag="ACG84Z_001537"
     CDS             complement(26934..28157)
                     /locus_tag="ACG84Z_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFP9162388.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28174..29220)
                     /locus_tag="ACG84Z_001538"
     CDS             complement(28174..29220)
                     /locus_tag="ACG84Z_001538"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFP9162389.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29384..31111)
                     /gene="ptsP"
                     /locus_tag="ACG84Z_001539"
     CDS             complement(29384..31111)
                     /gene="ptsP"
                     /locus_tag="ACG84Z_001539"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFP9162390.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRGLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(31111..31377)
                     /locus_tag="ACG84Z_001540"
     CDS             complement(31111..31377)
                     /locus_tag="ACG84Z_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFP9162391.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31856..34090
                     /locus_tag="ACG84Z_001541"
     CDS             31856..34090
                     /locus_tag="ACG84Z_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9162392.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34238..34558
                     /locus_tag="ACG84Z_001542"
     CDS             34238..34558
                     /locus_tag="ACG84Z_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFP9162393.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPQH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT         9774 a         7485 c         6040 g        11304 t
ORIGIN      
        1 tacgttttgt tattctaaaa aacttatata aaaaatagta aggtttttat ttcgaatcca
       61 taaaatattc ttggattgct tctcgtgttt ttttcacttt ttcgctaagc ttttcgtttt
      121 tagccatata gaaataaaaa atgatatcga tcgtagcaaa ttgggccaaa agtgaattag
      181 ttgccgcact tcgattcgtg atttcttttg gtctagatgt ttgtacgagt acatcggcta
      241 tcttgctaag cgggttattt ccaaattgcg tcaacgcaat gatttcgata ttcatgcttt
      301 tcgccagctc ggctaatgcg actacatctg cacttctacc tgagtttgaa acaagccaaa
      361 gcactttctt tttctcattg ctgacaagtt gcgggagcaa gacgtggata tctttttcaa
      421 aaatgattgg cttaccgaca cgagaccatt tttgcagaat atcttctact actaaagaag
      481 aggcgccaac cccatataaa aaaacagtct ctgccgattc caaacactct acgacttttt
      541 ggatcgtttc ttcttctaga atatctactg tttcttttat cgctacttgt gcattgttac
      601 caagtttgtt tttgatagag taaaaggact catttgcttc tatatcacta aaaccttcat
      661 cgattccagt ctgtagttct gttgaaatcg tgattttgaa gtccgtcaga ctttgaaaac
      721 cgattttttt ggaaaaacgt acaactgtcg gcgcactcaa cccggaagct tctgctaatt
      781 cattagctgt cattgtaggg accttctcaa tattaccgat aatgtagttg gccaactttt
      841 tttctgctga agaataatct tccatcatac tttcaatacg actaattacg ctcataagtt
      901 cctccaccct tttaatgata gtctatgtaa gtataccata tcagaccctt attcacggtc
      961 gtatactgga taaaaaacaa aaaaacaatc cgcccaacag aatatcttat cccatcaatc
     1021 ccacagattc tattgagcat ctgtgtcttt gaggaatacc tgttatctat tgttcggatt
     1081 gctttctatc tactactttt ttacaggaaa tttacctatt agttttctct gctgtaattt
     1141 ttgacttctg cttccatagc atcaataaag atattcaaat cttctacagc tgtttcttta
     1201 cttccataac gacgtacgtt cactgttgca tcttccaatt ccttgtctcc aacaactaat
     1261 tggtaaggga tcttttgtgt ttgagaggca cgtatcttat agcccatttt ttcattacga
     1321 tcatcaactt ctacacgcaa ccccttcatt tgcaaacgtt ctttgatttc ataagcataa
     1381 tcgccatgtg catcaacaga aacagggatg attgttgctt gtataggtgc caaccatgtt
     1441 ggaaaagcgc ctttgtatac ttctgttaaa taagcgacaa aacgttccat tgtagaaaca
     1501 attccgcggt ggataactac tggacgatgc gtattttccc cgtcttctcc aacatatgtc
     1561 aaatcaaagc gctctggcaa taagaagtct aattgtatag ttgataatgt ttcttctgta
     1621 ccaagagctg ttttgacttg aacatctagt tttggtccgt aaaaggctgc ctcgccttct
     1681 gcttcaaagt aatctagttc taattcatcc atagcggctt tcagcattgc ttgggctttt
     1741 tcccacattg cgtcatcatc aaaatattta tctgtattgt ttggatcgcg atagctcaag
     1801 cggaaacgat aatctgtaat attgaagtca gcatatactg ccaccatcaa ttcaagcgta
     1861 cgtttaaatt catctttgat ttgatcagga cgaacaaatg tatgaccatc attcaacgtc
     1921 atttctcgta cacgttgtaa acctgacaaa gcacctgatt tttcatagcg atgcatcatt
     1981 cctaattcag cgatacgaat tggtaattca cgataagaat ggatcgtgtt tttgtagacc
     2041 atcatgtgat gagggcagtt cattgggcga agaacaagca tttcgccatc tcccatatcc
     2101 attggcggga acatgtcttc ttgataatga tcccagtgtc cagatgtttt gtacaactca
     2161 acatctccca ttattggtgt atatacatgt tggtaaccta gactaacttc tttgtctacg
     2221 atataacgtt cgatcgtgcg tcggattgtt gccccttttg gaagccagaa tggcaaacca
     2281 gaacctactt ctggggaaac catgaacaag tcaagttctt ttcctagttt acgatggtct
     2341 ctttcttttg cttcttcacg gagacggata tattctttca aagctttctt gtcaaaaaag
     2401 gctgtcccgt atacacgttg catcatttga ttgtttgagt ttccacgcca ataagcacct
     2461 gccactgata ataatttaaa tacttgtata cggccagtgg atggaacatg tggtccacga
     2521 cacaaatcga tgaattcgcc ttgttgataa gcagtaatca cttcttcttc tggcaattca
     2581 ctaatcagtt ctactttgta cggatcactt gcaaaaattt ctaatgcttc ctgttttgaa
     2641 agaacacggc gttcgatcgg cagattttct ttgacgattt tcatcatttc tgcttcgatt
     2701 gccggcaaat cttctgcagt tacttggttt tgtccattat ctgtatcgta gtaaaaccct
     2761 gaatcgatag ctggtccaac gccaaagtgg atatttggat agaggcgacg catggcttgg
     2821 gccatcaaat gagctgctga atgacggact aagccaagtg catcttcatg gtctggtgtg
     2881 atgatctcaa tacttgcatc ttcctcgatt ggacgagtca aatcaacgag ttttccgttc
     2941 actttaccag ctaaagcttt ttttgctaag ctttttgaaa tgctttcagc aattgccaat
     3001 gttgttgttc cagactcaaa ttctttgact gcaccatctg gaaaagtaat ttttatcata
     3061 atagtttcct ccttgaaatg ttttgattga tcagatcatc aagctgaaaa acaaaaaaat
     3121 cctagcatct cttgaaaaga gatactagga cgaaaagttc gtggttccac ctaatgttca
     3181 aacgcaaatg cgttcctcaa gcgttgtaac ggtccgaccg cccttgcttc aacaagggtt
     3241 tcgaaagtgg tcatcctttg gttttctcct ggaaaagttt cagcctagct tttcctctct
     3301 tatcgaagac tctcaaattc agttggcttt ctcatcaatc aattatgtgt ttatttaacc
     3361 actaataaat agaaaaatca agtgggaaac taaacttatt ttttccattc cccatttaca
     3421 ccgtatgttc cttttttcat ctcattgatg atgacatgga tgtgttcttt tggtgcctgc
     3481 gtgtttttat gaacagcttc cgtgatatct ttcatcatat tttctaattg ttccggactg
     3541 cgaccttcta ctaattcgac atgtacgaat ggcataatgc tctctcctct ttctgatcgt
     3601 tcttttttca actcgattct atcatactat gtttgtcttg ggtactgaat caggaaaaat
     3661 ggctggatct ttttttgctc tcaaggcact caaaatagag accgtatcca cgacttcttg
     3721 caaaacagct ccgaataatg cggggattag tcccgtactt gcaattaaca tcaaaaaaat
     3781 acaaataaag atgccaatca gtacagactg tttcgctatt ctcatcgtat ctcttgaaat
     3841 cactactgct tttgctacac gcaagagatc atctttcaag atgaccgcat ctgcactttc
     3901 actagcagct gtagaaccat gagcccccat tgcaataccg atatctgcag cagcaagtgc
     3961 tggtgcgtca ttcacgccgt ctcctaccat cgcaacaggt ctttgatctt tagggatact
     4021 ttctaaaatg gtcagtttat cttgaggcaa gctacgggca tgtacagaat ctaattggac
     4081 tttttctgca atcgtttgag caatggcaga tccatccccg gtgatcatca tcaaattttt
     4141 cacatcaagt tttcttagct ccttgattgt ctttgctgct tctgggcgaa tctgatccga
     4201 aaataggatc gttcctgcaa aagatcgatc aattgttaca tagattgctg tattggacgt
     4261 ttctatttct tcagctgaaa caaaagaggc acgtccaatc tttacttcat gattattgac
     4321 tactgcttgg attccttgac cggtcacttc tttcagttga ctaacaggat acagttggct
     4381 gtttttcacg ttgttcacta acgaacgagc taagatatgg ctagattcct gttctgcact
     4441 agctgcatac agaagtagct cttctttttt tattccattg actggctgaa tcgcctctac
     4501 ttccaatatc cctttggtaa gcgttcctgt tttatcaaaa gcaatcgttt ttgtacgtgc
     4561 gagcttttca atcgttgttc cagtttttac aacgatcccg tttttacttg aacggctcat
     4621 tcctgcaact aaagcaatgg gcgcagctag aatcagtgga caaggtgatg ccactaccag
     4681 tacctcagca aatcgtaaag ggtcttttga gaaccaccaa gaaataccac cgatcaaata
     4741 agcaatcaac gtgaaaggga ctgcataacg atcagctaaa cggacaaatc gggcaggctt
     4801 ttcttttgat tcttcgacta gtttaataat catttgatac tggctgtctg cggcacgttt
     4861 ttcagcgatc atttggatcg atccgtctcc atttaaagac cctgacataa tctgatctcc
     4921 aggtttcttg gtttccgggc gggactcacc tgtcaaagaa gattcatcga ccgaagattc
     4981 tcctttggtc actcgaccat ctgcgggtac aagttcgcca ggcttgacta gtaactggtc
     5041 atcaatattt atttcatcga ttactatatc ctgcaatttt ccttctttga atcgatgggc
     5101 aattcttggg gtgttatcta acaaagactg cagttcttta cccgctcgtt tattcgcgta
     5161 atcctctaga ctatctccgc ccgtaagcat gatcaatatc atcaaactag cccagtattc
     5221 tttgacggct aatgttgcaa ggattgcggt aatcgctaat acatctacgc catatcttcc
     5281 tgaacgtaac gtcttgatca tttccaaaaa catcaagaag gcgagaatcc ctccagtaaa
     5341 tgcgacaatc gcaaatgcaa gggccggctg gtgaaaaaca aattcactta ataaagctat
     5401 cccaccaata agcaaagtaa gtaaaaattt tttgaaatgt gtcattgttt tttctcctct
     5461 tttatgtgac ttagagaggt tagtaataaa tttccagctg cctctttcat cttaagcata
     5521 gtccttgact agcacttttt aaaacaatag gccttaattg aaaacaacta tcactatcag
     5581 cgtttccaaa attcatcagt tctacaaaca aaaatattca gcaaggatta ctttttcgat
     5641 tcatcagtta aaaagtacct tttttcgaaa aactatgcta tacttttaat tcgttattta
     5701 cggcggaagg agcaaacatg cgatgaatga gaaacaacta gaacaaacgc acgtggatga
     5761 aacgatcgaa ctaatccaga tcgaacaaaa tatgctggat acaaaacaac aagaattgac
     5821 tcaggaaatg aatcattcga caaaagacac agctaatcac aagattcgag ctggttccaa
     5881 tgaagctttt tatgaatctg ctgttgaata tcgccaacat gagcaggaat tgcttttgaa
     5941 ataccatact cttgaagcac agcaaaaacg cctgcaaacg ttgtctgtca tgaaagatag
     6001 tccttatttt gcccgtatcg actttaaaga agaccgtgaa acagaaacat tatatctagg
     6061 tatcgcttct ttaagagatc tggcagaaga aacaatcgtt attgactggc gcgcaccaat
     6121 tgccaatctt tattatgaag gtgagattgg tcccgcattt tatgaaactg aaacagatag
     6181 aatagatgtc gatctgcagt tgaaacgaca atttaaaatc caagaaggac gtattttatc
     6241 tatggtagat acgtcggaag taatcaatga tgactttttg ctagagatat tggatgaatc
     6301 atcaagcaac catatgaaaa acatcgtctc tacgatacaa aaagcacaaa atgcaatcat
     6361 tcgggacaca acaagtaaag taatgctgat tgaaggaatc gccggaagtg gaaagacatc
     6421 cgctttgctt caacgtattg cttttctgtt gtatcataat cgcaagtggc tcgaggctga
     6481 aaacgttctt ctattttcac ccaaccattt gttttctgat tacatctcga ctgtattgcc
     6541 ttcattaggt gaaagcggcg tgcctacaca gacattcaaa aattatttgg tgcagctgct
     6601 gccagagttt tctttactag atgaacagca acaagaaagt ggttttttgc taggggaaaa
     6661 agatccgata caagtgatga aaagcggatt gaccttagtc gatcagattg atcgctatat
     6721 ccaaggcatc acaaactacg gtcccttgtt ccgtgatatg aaaataaatg gccgtacgat
     6781 cctatcaaag gaatcgattc gccaatggta taaagaaaca aatgaacaat tacctttaca
     6841 tcatagactt tctctattac aaacgaagct cctgaaaaaa ttaggcggtc tgcaaaaaga
     6901 cgaaacacgt cagcaatggg tcaaagatct ggcggaagaa cagctccaag aactatacgc
     6961 aacagatcca aatcttgaat atacagaaca aaaggagcgt tcattacgta aaaaactggc
     7021 caaccaaatc gtacgtaaaa gattccgtcg aatccatcga gggatcatga attatcaatt
     7081 tgtcaatata acgaaacaat atctccactt tctacaaact gtgccacttt ctcttctaac
     7141 acgacataaa atcagcgaga ccaggtggca ggaacatttg acaactgttc gtacacactt
     7201 gcgtcaaaga gaattgcgtc aagaggatgc tgtactattc tttttactga tgcgccgaac
     7261 atatccagtg acggttacac acaaagctcg ctatatcttt attgatgaaa tgcaggattt
     7321 cgcaccatca caagtggcat tgctgcaagc cttgttccca aaagcaaatt tgactttctg
     7381 tggagatcta aatcaaaatg tctttggaaa tgaaacgatc gttggatcat tggaagacct
     7441 tttcgtggac cgtgaagtca ctcgtttcca attaacgaca agctatcgct ccacaaaaga
     7501 aatcactgat tttgctaatc attttattgt gaaagaacat caagtagaaa caacagcaag
     7561 aaaaggagac cttcctttgc tcatccaagg aacaacagat gatatcaaat tgaattggtt
     7621 agcagatacc attcgaacga ctcagggaaa agcccggtat tggcgtacag caatcatagc
     7681 taaaacacaa gaagaatgcg aagctcttta tgctcaactg ccagacgagt tgaaacaaca
     7741 agtccagctg attttaaatg agagtgactt tatgaagcgt tccattattt tacttccagc
     7801 ctttttagca aaaggtctgg agtttgaccg agttttcttg tgggatgtag atgcagaaca
     7861 tttttcttct cagcaagaca aattgatcct ttacaccatg tgtacacgtg cgatgcatga
     7921 attgaccctt tttacctcca ataatgaaag tcctttgtta aacaatatgg atatttcatc
     7981 ttatgagaaa aaagtactgt aagtaaaaag acaactgcta tcattaatgt tagcagttgt
     8041 ctttttattt acaataataa ttgcagaaaa agtaattcaa tcatttaagg tcatttattc
     8101 tatatataaa tccaaatctg tttcaggata ttttaatttg acaagcgaaa taatcatttt
     8161 cagttcttcc atgttttctg gatattctgg gtcaaatacc ttgctatgac ggccaatccc
     8221 gccattgtcg atcaatcggt aaattcgatt ccattcaatg aattggtcaa ttgattggaa
     8281 attgctgatt ggatagccgc cacaatccaa aatctctgat acacgaaatg ctaggtatgc
     8341 actatcgatc actttatttt ttttcgtgtc tatcttctca tttctttcga taagaatttt
     8401 ttcaggacga tgtttcaagc tccactctaa tagtagaaag aaagcctcca tccgatactc
     8461 ttcttcaaat aaccgaaagg ctgaatcaga acgacgaaaa agcagcggaa tcagataatt
     8521 ttgtctataa atcagcattg gtgcgcggtc caccatacac tctaaataac ggttcagata
     8581 ccctgtaccg acatagtttc ctaatcgata gccttcaacg ccgaatcttg cgtatttttg
     8641 cgctaatttt gaacaatcag ttacgttcac agctaactct tctactttgc ggtaaccgct
     8701 taagatacgt tcaaaaggtt ctaaagtgat ttttgcttcc atattcttcc ccgtccatct
     8761 tccacatact tcatatcatt tcacatgata cttatgctct catcatacca caggttgaat
     8821 tagaaaagaa aataaatcac acaaaaaagc aagacaatct gttagtgaga ttgtcttgct
     8881 tttcgaaaaa gactgaatac ttttcgttaa aactggttgc ttagtcttct aatgccacat
     8941 tatggaacac atgctgtaca tcttctagat cttccagtgc atcaatcatt ttttcaaatg
     9001 tttcttgatc ttctggagat agtgttacct cgttttgagg gatcatttgg atctcagcga
     9061 ttgaaaaatc agtgattcct ttttctttta atgcttcttg tatactatgg aaatccgcta
     9121 cttcaccgta aacgatgatt tgtccttctt cttccattac atcgcgaaca tcgatgtctt
     9181 tttccattag gtattcaagg atctcgtcag cgtcttctcc tgcaaaagca aagattgctg
     9241 tattgtcaaa catgtaagaa accgctccgg aaacacccat gttcccgcca tttttcccaa
     9301 atgctgcccg tacgtctgct gctgttcgat tcacattgtt cgtcaatgta tcaacaatca
     9361 ccattgagcc gcttggtcca aatccttcat agcgcaattc agagtatgtt tcatctcctg
     9421 caccttttgc tttttcgatt gctcggtcaa taatatgttt tggtacatta taagttttag
     9481 cgcgatcaat gacgaaacgt agtttttggt ttgcatgcgg atcaggatca cctgattttg
     9541 ctgccgcgta gatttcaatc ccaaattttg cataaatccg gctattatta gcatctttag
     9601 cagttttctt tgctacgata tttgcccatt tacgtcccat attttcactt cgctttctga
     9661 tttgatagtt tcataacgca aaaacgtcct gttccattat acttgtgaat cacgattctg
     9721 tgaagctttt tttctttctt ccttcattct tctcattttt agtcaattat ctatactcgg
     9781 attgggattt gcccgaaatt ctgttccgga atattgcctc ccaattgata gatttgatca
     9841 cttctaacta acagttccgc ttcttgtgcc tctttttttc cgattcggga ataaatagaa
     9901 atctcttttt tttcttttaa gaatcttctt ccagcatcgg taaatccaag tagtcgaaga
     9961 taatttttat tttgttggac aggaatctct tgctttttga tattcagcaa gacataacaa
    10021 gataatcgtt ggatccgtgt ccatgtatat ctttttgttt ttacctttga cacaaaatcc
    10081 tcaaaactat cagcagttgc agctgctgtt ttcatgcgcg attctattcc ttcggtcatc
    10141 tgatagatat ctgtcagttc cagcaaagta gaagataaca accgataacg caaatacggc
    10201 caataagatt cccaagtctg cagcgaacaa gttgaaagat cttcttctgt ctgaggcggc
    10261 acaagtccag ctattctttt tccttcttct aacgcatggc gaatggctgt tgcactggct
    10321 atcctctgat ctgtgatgat tttttcatga tagcctgcac ttttacgtcg gatcggatgt
    10381 aattccatag ggtggacata cttggcattt tcctttgcat aacttaatcc caagatatga
    10441 tttggcgaag aaaaatcaag cgtaatatcg ggatacagac tgcgaaaaac ctcagtcatt
    10501 ttttgcggat aactatacgt ttgatcagac agttcttgaa atgcctcttc tatcctatct
    10561 tgattctctt ggacaaagcg tccgaaactg ctgtaatcaa acgaagtctc ttcttctgtt
    10621 ccaaaacaca aactgtcaca gtccagtgtt tgcaagattt ttactgcacc tttagcaaaa
    10681 tagtcagctg actgaaccgc ccattcgacg ggaagctcca ctactaaatc cacaccattt
    10741 tgtaaagctt cattcgcgcg atgccattta tcgatgatag ccggttcgcc tctttgcaaa
    10801 aaattcccgc tcattacagc aatgacgacc tctgctcctg ttatttttcg tgccatttcc
    10861 acatgatagc gatgtccatt gtgaaaagga ttgtactcta cgataatccc gcagcttttc
    10921 atgcgcatcc tccttcatag ttatcgataa aaaagaaata gagacaagta aaaaaaggca
    10981 aaaatcggaa aaaatacccg aactatataa actattctcg caaacacaat acttctgcga
    11041 cgaaaagctg cactgcaaga gcaatgccta tatcgttcgg atatataatt tatgttgaag
    11101 atttattctt ttcttgttaa ctcgagcagg caaaaccgct agtctttgta tgctacaaag
    11161 aaccagcgct ttgatttctc tgatgctgct tcgtctgtaa aatcagaaaa tgcttcgact
    11221 ttcgaaaagc cgctgttttc cagcattctt aaataacttt ccaatggata ggtacgctct
    11281 tgatgtagtt catcttcacg aataaatcga ccagaccctt cttgttcttc aacgaaaaag
    11341 gtaagaaaat gttcgatgct gtgtttctcg cttcctggat aactatccca caaaaaagca
    11401 aaattatccc cttgataatg atagctatat tctggaaaaa cctcatctac ttgataggtg
    11461 gagtgtacgt caaataaaaa tcggccattt tcttctaacg cttgatagac ttcatcaaac
    11521 acttgctgta cctcttgtct atttttcata tagcacagcg aatcagaaaa acaggtaatt
    11581 gcctgatatt gtccgatttc tgataaatcg agcatattgc cttccacaaa ttggatcgat
    11641 gcgtcttctt catatgctcg ctggctggca atcatcaaca tctcttctga aaggtctaac
    11701 cctgtcactt tatatccatc ttttgcaaag gcaaccgcta atgctccagt accgcatgcc
    11761 agttccaaaa tattttttgt gtcttcttgt aaatgacgtt tcgaaaaagc taaccattgc
    11821 tgataaagtg tttcgtccat cacttcatcg taaatgaaag caaatgtttc ataagccata
    11881 tgttaatcca accattcact aagatcgact agcggagcat ctgaccatag tttttccaga
    11941 ttatagaaat ttcgttctgg cgcatggaaa acatgtacga tcacatctcc aagatcgatc
    12001 aatacccatt ttccgccttc ttttccttca atacgtttta cttcatattt gttttcttct
    12061 tctttatcaa tgatttcttc tgtaattgcg ttgatttgac gttcgctatt tgctgaacag
    12121 atcatgaaat aatctgccaa caaggaaaca tttcgaacgt ctaaagcgat aatgtcttct
    12181 gcccgttttg aatctgctgc ttcaatcgca atttttaatt gttctttact atctatgatg
    12241 atttcctcct aatatgagca gcttattttt ttgctaccca gtaattatat gtttcgattg
    12301 tttttggata aatctgttgt tcttgcgcaa gcaaatgggc caatgtatgt tttgtttcaa
    12361 atgctacagc ttcgtctaga tcagcccatg caatggctcg tgcatcttgt accccaggaa
    12421 aatctcgacc tggttcaata tagtctgcta cataaatgat tttgtcaagg agactcatct
    12481 tagcagcccc agtcgtatgc acccggattg catgaagaat ctctgcatcg gtgattccta
    12541 attcccgctc tacaaacgaa gcgccaacaa gaccatgcca gattgcatta ttataattca
    12601 ataactccgg atcaaaaccg tctcttacga ttaccatttt gaactcctca tctggtcgtt
    12661 cttttgcata atcatgtgtc aatgcagcaa tactagcttt ttcaggagaa gcaccgtatt
    12721 ttttggcaag agccacggct gtttcttcta ctccaagcac atgcttgaag cgttgttcgc
    12781 tcattctcat ctgtattttt tgcatcaggt tttctctaga ataagcagta tattcattac
    12841 tatagtccat attcatacaa cccttcattt tgaatataat caattacttt atctggaaca
    12901 aggtagcgga tagaacagcc ttctttgatc ttttgacgta ttttcgtgga actgatgtcg
    12961 atctcaggta catctaccca aattacagga tatggagtat ccgttgtgta tcctggtcga
    13021 cgtataccca caaagttgac catagaagtc agctcatcga ttttatacca ttttggcaaa
    13081 tattctacca tatccccacc gataataaag taataatctg tatccggatt gttttgcgtc
    13141 aattccttca tagtatcata ggtgtaactt ttcccaccac gagctaattc aatcgtttca
    13201 atctgcaaaa aaggattgtc ttccaccgct aattccaaca tgttgagtcg atgttttgca
    13261 tcaatcgtct gtttctcatc aacatgaggt ggctgataag aaggcatcaa aaatacgcgg
    13321 tcaagaccta aattccggcc agcttgttca gccatcacta aatgtgcaag gtgaacggga
    13381 ttgaatgttc cgcccaagat ccctacttgc tttttcttct ctaagaattg aggcatttct
    13441 tcaggaaata attgtgaacg aacaaatgtc ttagcttgcg tattcatcat ggtcactcct
    13501 tatattgctt ttacttcttt tgatagcctt tgatactttt cttttgtgga aggtttgtat
    13561 aatacaataa cacgtccaat gatttggacg atttcgcaat ctatttcttt ttctaatact
    13621 tgagctgctt cttctgcaat ctcatctgta ttttgaagta acgatacttt gatcagttct
    13681 cttttttcta aagcttcttc aatttgaacg atcattgctg aattgatccc accttttccg
    13741 atttgaaaaa tcggctgaag atgatgcgct ttgctacgta aaaaacgctt ttgttttcct
    13801 cttaaactca taattttcct tcttccttaa atcaatgctt tgcgtttcaa tacatctaca
    13861 ccctttggcg cccagcccgc aattactact ggcgctgtta cagtgatcca gcctagaccg
    13921 gcaaaaacga tgtctgtttt ttctttcaca gaaaactcaa aacgaacaag ctccggaaat
    13981 gcctcgactt catcaggacg aggaggctgt aataatccac ctacatgttt ttgataaaat
    14041 tcgtctgctt tttccagttt cgttcgatga atatttacat catttgacac ataagcaata
    14101 aatgaagcac gattgccgct gataaaatca aatcttgcaa gtccgcccaa gaaaagtgtt
    14161 tgcccttcat tcagctgata aactttaggt ttgatttctt ttaacggtgc aatgatccgc
    14221 aaatcttttt tacctaagta gtgcgccatt tgatggcgat ggataattcc cggtgtatca
    14281 atcaaaaaat gcccgtcatc taaaggaatc tcgattttat ccaaggtcgt tcctggaaac
    14341 tgcgaagttg tgattacatc ttgtactccc gctgtatttt tgatgatttg attgataagc
    14401 gtcgattttc cgacatttgt tactccgacg atatagacat cccgtccatc gcggtattct
    14461 tcgatttttt ctaatagttc cgtcatctca tgagatttct tagcactagt taataataca
    14521 tctactggac gaattcctgc ttcgtaagca cgttccttca tccattgtgt taatttagtt
    14581 tttttcaatg atttaggtaa tatatccact ttgttcccaa ctaaaagtac tggattgtca
    14641 ccgacaaaac ggtgtagtcc tgggattagt gaaccattga agtcaaaaat atccaccaca
    14701 ttgacgatca atgcatcttt ttgccctaat tcattcagta agcgcaaaaa gtcgtcatcc
    14761 gtcaatgaga catcttgggt ctcattataa tggcgtaatc tgaaacaacg ctgacaatag
    14821 acttccccgg aagctaaacc tttttccaaa gccgtttgcg gcgtgtatcc taattcaccg
    14881 ggtttgtttg tttgtataac ggcaccacag ccgatacatt gtaattcttc tgtcattcga
    14941 ttccacctcg ccagcccata tcagggtgtt ttgctaatag ataggccata attctttttt
    15001 cccaaaaacg attaaattgt gtcttccaac tatctgttgc gataatgggt tttacaagga
    15061 tgctacgtat ccctgcacga ttggctccac gtatatcagt cataatctga tcgcctacca
    15121 ttactatctc atcatctgct aaatccaatt gtttctttgc tatgttgatc cctcttgcta
    15181 aaggtttcat tgctcgtgca acatacaaaa gatcaaattt ttcaatcgct cgcgcgacac
    15241 gttttgaatt attgtttgaa acaacaacaa cagggattcc tgcatttttc atttctaaaa
    15301 tccaagtaag caactcttct gttccatctg gattattcca tgcaatcaac gtattgtcta
    15361 aatcggtcaa tactgctttg atgcctagat tctttaattg ggcaggtgta atctgataga
    15421 tggcttctac catccatgtt ggtttgtaat ttgaaaacat gctgtctcct catctgcaaa
    15481 aaatgaagga gcacataaag tactcctcaa ccccgtatta tactgcatat cagcaaaaaa
    15541 aactacctct atactcgttc gtctttcaga aaaagcattt ctttacaaaa tgaccaaaaa
    15601 taaagattga tcacagaaaa atttagaaac aaaaaacaac taatattggc ggaacctctt
    15661 gtatcgtttt tccagtaatt tatgctgatc taatcgaaca agttccgtca atctttcaat
    15721 caacgctttt ttcataatgt gtgcgacttt atatcgtggc aactgctcgc cgttgaacgt
    15781 ttcaggaata actcgatcaa cgattcctaa ctcgcgtagt tctggcgcag taattttcat
    15841 caactcagct gcttctgcgg cgcgactacc gtctttccac aaaatcgacg caaatccttc
    15901 tggagaaagc acagcataaa tcgtttcttc cagcatccag acttcatccg ctaaacctag
    15961 agcaagggca ccgccacttc caccttcacc aatgatgatg gcgatgatcg gtacctttaa
    16021 atcagacatt tcgagcagat ttctggcaat agcctctcct tcgccgcgct cttctgctcc
    16081 tacaccgcaa tatgcacctg ctgtattgat caaggtaatc accggtctat tgaacttttc
    16141 cgcttgtttc atcagtcgta aagcttttcg atagccttca ggatggggag aaccaaaatt
    16201 tctgcggata ttttcctgca gatcccgtcc tttttgaata ccgatcactg ttaccggttt
    16261 gccatctaat cgagcgattc caccaacaat cgcttcgtca tctgcaaata aacgatcacc
    16321 atggcattcc tcgaaagaat cgaagatctc ttcaaaaaaa tccaagcttg tccatcgttc
    16381 tttagctctt gctaactgaa cgacatcatg tgctgtctta tccacgatct atccatcctt
    16441 tctgtgtatg caattcaaga agcgtatgga ttttctgttt caattccatg cggggaacaa
    16501 tctgatcgac aaaaccatga gataataaga attcagcctt ttggaaatct tctggaagtt
    16561 cctgcttgat cgtctgttcg atgacgcgtc ttccagcaaa accgatcaag ctttggggtt
    16621 ctgctagaat aatatcgcct tccattgcaa aactggcagt tactcctccg gtcgtcgggt
    16681 ccgttaaaac agttagataa aaaagacctt cattgctatg ccgtttgaca gcagcagaga
    16741 tttttgccat ctgcattaga gaaaagattc cttcttgcat ccgtgcgcca cctgaagctg
    16801 tgaacaagac gactggaaga ctttcctttg ttgctcgttc gaataatctg gtgatctttt
    16861 ctccgacaat cgttcccata cttcccatga taaaattagg atccatcact ccaataatga
    16921 agggaatccc ctgaatggtt gctttaccag tgaggactgc ttcatgaagt cctgttttat
    16981 cttgcatttt tttaattttt tccgtatatt cgggaaatgc tagcggatct ttggttacaa
    17041 gatccgtatc ccattcttca aaactttttt catcaataat caaagctaga cgctgccatg
    17101 caccgattcg aaaagcgtat ccgcaatgag ggcatacttt ttcttcaccg atgtctttcg
    17161 tataaaggat atgtttgcaa tttggacact ttgcccacat gttatcagga acagatggcg
    17221 agttagcagg tttgctctct ctattaggat tgatccgaat atatttcttt ttcttaaaca
    17281 gagccatcta tgcgcctcct atctccgttt ctggtgtcca attcggtaaa aattcttctt
    17341 gtaaaaatgc tgtgctgtaa tcacctgcta tgactgcagg atgactaatc aaatccatct
    17401 gaaattctgc gttcgtgatg attccttctg tgataaattc acttaaggct cgctgcatct
    17461 tcattaatgc ttcaaaacgc gtatttccat ggacgattat ttttgcaatc attgaatcat
    17521 aatatggcgg gatcgtatat cccgggtaaa ctgcactgtc tactcgcagt cccatcccac
    17581 ctgctggaag cagtaagttt tggatcttcc ctggagaagg agcaaaatgg aaagcaggat
    17641 tttctgcatt aatccggcat tcgattgcgt gtccttggaa tactacttct tcttgacaca
    17701 cattcaaagg ctcaccggct gctatctcca cctgtttttt tactaaatcg attcctgtga
    17761 ccatttctgt tactggatgt tccacttgga ttcgagtatt catttccatg aaataaaaat
    17821 cgccttcttc atccatcaga aactcgatcg ttccggcatt ttcataattg actgctttag
    17881 ctgctcgaac agcagcgtct cctagtgctt ctctttttgt ttgtgagatc actacagaag
    17941 gagattcttc cagtactttt tgattgttgc gttgtaaaga acaatctcgc tcgcctaaat
    18001 gaatgacatg accaaatcga tcacctaaga tctgaacttc tatatggcga gcaggataaa
    18061 tgattttttc caaatacata tcatcatttc caaatgccgc tgctgcttct tgctgagctg
    18121 aagaaaaatg ctgtgggagc tcttcttttg attgaacttt ccgaatgcct ttcccgccac
    18181 cacctgcagc tgctttcagc atcactggat aaccaattct gtctgctatt tccaatgctt
    18241 cttctactgt agataataca ccagtacttc ctggaatgac tgggacattt gcttcttgca
    18301 tcaattgacg cgcattgatc ttatttccca ttgcatcgat cgttgcactt ttaggaccaa
    18361 taaatgtgat attgcactct tcacacatgg aggcaaatcg gctattttca gataaaaaac
    18421 caaatcctgg atgaattgct tcggcttttg tcacgattgc agcgctcagt acttcctgaa
    18481 cattcagata tgaatcaacg gcttttgccg ggccaatgca gattgcttca tctgctaact
    18541 gtgtatgaag tgcttcggca tctgcttctg aatatatcgc tacggtttgg atccctagtt
    18601 cgcggcatgc acgaatgata cgtacagcga tttcaccgcg gttagctatc aatactttag
    18661 aaaacatatt tcacctatcc aatcataaag gttaattccg cttcggctac ttttttaccg
    18721 tctactttag cgattccttt gcctattccg gctgaagctt tcactttcaa tatctcaact
    18781 tcaaggtata aggtatctcc cggtgtaact ttcttacgga attttgcttt gtccaatccg
    18841 ccgaaataag ccgtctttcc cttgaattgt tcaagagaaa gtaatgcaac tgctcctgct
    18901 tgagccattg cttcaacaat caatacccct ggcataacag gttcttctgg aaaatgtcct
    18961 tgaaaaaagg gctcattgat cgttacattt ttcttagcaa cgatccgttc tccttcaacc
    19021 atttcttcca ctcgatcaat caaaagcatt ggataacgat gtggaatgat ttcttttatt
    19081 tcttgtatgt tcattgtttt ccctctttcc tgctttgctt atttttgctg aatcctaaag
    19141 agtggctgtc catattcgac aactgactcg ttttctacaa ggatttctgt gatcactccg
    19201 tcggcctcac tagttatctc attcatcagt ttcatcgctt caataatgca gataacttct
    19261 cctttggcaa cttgatcacc tacttttttg aaagctggtt tgtcgggcgc tggttgcaga
    19321 taaacgattc ccacgattgg cgaaacaacc tcgattccat caaatactgc cgattctttt
    19381 tctttcatta tttctggagc agttgttgct tgttcaggta tgacattgac tggctccgaa
    19441 actggcaacg tttcgtttgt ttgaaccata ttcatgcctc gacttgtttt atttttattc
    19501 atatacaatt caaattgacc ttcacgcaaa tcgaattccg ttagcgagga ttgatcaaat
    19561 tgactgacta attctctgat ttcattgata tccaaaatta ttcctcccag cgtttcatgc
    19621 acagaaccgc attatgtccg ccaaacccta atgaattact cattgcataa gtaaaacttg
    19681 caggtttgct ttcgtttttg acaactgtca agtcaatctc aggatcttgt ttttctacat
    19741 tgatcgtagg tgggataaat tgatgttcta atgccagcaa agttgccaag gcttcgatcc
    19801 cgccggctgc tcccaataaa tgtccagtca tcgatttcgt gctgctgacg taagtatctc
    19861 tgaaattttc acctaatgcg atttggattg cttttgcttc tgcctggtca ttggctggtg
    19921 tacttgttcc gtgagcattg atatatccga cttgttccgg ctgtacacca gcttcttcca
    19981 tcgcaagctt cattgcttta gatgcaccag aaccatctgg agtaggagct gtcatatggt
    20041 aagcgtcaca gtttgcaccg tatccaacga tttctccata gattttggca ccgcgagctt
    20101 gtgcatgttc taaagattca agaactagaa cgcctgctcc ttcacccatc acaaaaccat
    20161 tccgattttc gtcaaacgga atcgaaccac gattaggatc agttgattct gagagtgctg
    20221 ttaaagctgc aaatccagca atccccatct cacaaatcgt tgcttctgtt cctccagcaa
    20281 gaatgacatc agaatagcca tgtttgatgt tacggaatgc ttccccaatt gaattcgttc
    20341 cgctagcaca agctgttacg atagctgtac aaataccttt tgcacctaca cgcaaagcaa
    20401 tatttccagc tgccatgttg gcaatcgcca ttggtacgaa cattggagaa actcgttttg
    20461 cacctttttc atgtagacga ataacttggt tttcgattgt tggaagacca ccgatcccag
    20521 atccgatgat gacgccaaac cggtcttgat tcattttttc tttatctaaa ccgctcatct
    20581 ccattgcttc taaagcagcg tagattccat agatcgaaaa catatccatt cgtttgctat
    20641 cttttttaat aaaatattta tcgtaaggga aatctttgac ttcacccgct aaggtaatcc
    20701 ctgtttctga agcatcaaat ttagtgatcg gtgcgatgcc attcgtcccc tcttttaagc
    20761 tattcaaaaa gctgtctgcg tcatttccaa taggtgaagt gactccatag ccagtaatta
    20821 ccactcgatt catttgtttg ctctcctttt cttatccgtg catgaccaat ccgccatcga
    20881 cattgatgac ttgtccggtg atatatggat tttgtgctaa gaaaactgct gtttgtgcaa
    20941 tatcttctac ttgtccgaaa cgctgcatcg gaatttgctt ttccgcttgt tccttgactt
    21001 tgtctgctaa aacttccgtc atatcagttg tgatgaatcc tggcgcaatg gcattacatg
    21061 taatgcctct agttgcagct tctcgtgcca cagattttgt taatcctact acgccagctt
    21121 tactagctgc ataatttgct tgaccaatat ttccaatcaa cccagataca ctagagagat
    21181 taatgatggc cccttctcgc tgcttcatca tttttttcaa tacgtgctgc gtcatattga
    21241 aggttccaat caaattgata tccagacatt ttttgaaatc ttctgcatcc attcgcatca
    21301 caagtttgtc atttgtgatt ccggcattgt ttactaacac atggatcgat ccaagctttt
    21361 cttctgcttc tttgatcatt tgtcccgctt tctcataatc agagatgtca ccggaaactc
    21421 ctacgcattt tacaccgaat gcttcgattt cttctatctt ttcttttgga atctctccgc
    21481 gaccattcaa aatgatattt gctccagctt ttgcaaaagc taaggccatc gctttgccga
    21541 ttcctcttgt actacctgtg ataaatacat tttttccttt tacatccata acgttcctcc
    21601 ttatagtatt gctattgttt catcaaatgt ctgcttattc tcaacacgca gaactggtat
    21661 tgttttatcg atttttttca taaatccgct taatactttt ccggggccga cttcgatgac
    21721 ttgttcgatg ccgattgttt ttaacttatg gatactctca tagaaacgaa caggttgcat
    21781 gacttgctgt tcaagtagtc ccgcgattgt ttctttcttc attatttccg ttgttgtgtt
    21841 gcttatgata ggaaaagaag gttcagagaa ttgaatctga cttaggtcct tcgccagttt
    21901 ttttgctgcc ggttctaaaa tagctgtatg aaaaggcccg ctgacattta gagggatcat
    21961 tcttttgaac cctttttctt ttaatagtaa aacagcttcg tctactgctt tttcttcgcc
    22021 accaatcacg atctgctgag gtgtattata atttgcagga gatacgatgc cgtacttgct
    22081 agcttcatga cagctttcct cgatcgtttc aatcggcgca ttcatcactg caaccatttt
    22141 cccgcttcca gctggggcag cttctgtcat ataagcgcct ctttttgcta ctaacgcaac
    22201 tgcttcagtg aaggatagcg cattactagc tactaatgcc gaatattctc ctaaactcag
    22261 tcctaaagct gcatctggga tgattccatg ctccttcaat aagcgataat acgcgatgct
    22321 gactgttaga atagctggct gtgtatattg cgtctgatcc aaacgttcat tttctgtaaa
    22381 gcaaagttca gccatatcgt agccgagaat ctcacttgct tcatcaaatg tctgctttac
    22441 aacggcttct tcatataaat cttttcccat accttgatat tgtgcacctt ggccactaaa
    22501 taagaatgct gttttcatgt ttttctccaa tatatccaga atatatgttt gattcttcct
    22561 attcaaaaag gccgagacat tcctatttca ggaaatgtcc cagcccccaa cctaatttta
    22621 atgattatgc agtttgtttt tctacgtaag tcactaaatc ttgaaccgtt ttgattccgt
    22681 cttctgtttc gattttcacg tcaaattcat cttcaatttc attgatgatt tggaataaat
    22741 ccaagctgtc agcttctaag tcttcttgga tgtcagtagt caatttgatt tcttcagttt
    22801 cttttcctaa ttcttctgcg atgatttctt gaattttttc gaataccata ataatatatt
    22861 cctccgatat tgtttgcttt ttatttttat aatttaacag tctacaactc catgagaata
    22921 cttccccatg ttaaacctcc gccatagcct gtaaatatta ctttctgctg ttttcctaag
    22981 gtgatctttc cactagaaac tgcttcatcc aataagatag ggatgcttgc agcagatgta
    23041 ttcccatatt tatccatatt ggtcaggaac ttttcttgcg gcatctttac ttttcgggca
    23101 attttctcaa taattctgag gtttgcctga tgcaaaagca gataatcaac tggtttgtct
    23161 ttcatgactt cttggatatt gtttgcaacg tctcgtacgg caaaatcaaa aatatctctg
    23221 ccagtcattt gcaaataata cgaaccttct gaatcttctg aatagaacgg atttttattt
    23281 tgctggtagc cagcggtcaa tgagctactt ctggtaccgt cagctgctaa tttttctttc
    23341 agcaattttt tctgtggatt cgcttctaag agaatcccac ctgctccatc gccaaacaac
    23401 acagcagtcg tacgatcaga ccaatcgatt agcttagata gtgtttcacc accaatcacc
    23461 agtcccttag ttgagccgca gcggatcatt ttttcagcca tgcttaacgc ataaacaaat
    23521 cctgagcacg cagcactgat atcaaaagcg atagcatgag ttgctcccaa tttcccttgt
    23581 acttgtgctg ctacagatgg tgtcgtgtaa tcgggcgaca ttgttgctac taaaataaaa
    23641 tccaaatctt tagggtttag atttttctgt tttatcaatt tttccgccac taaaatgcat
    23701 aaatcagaag tctcctgatt tgttacacat cttcgttcac gaatacccgt ccttgacgaa
    23761 atccattcat cagaggtatc catcatcttg gaaagatcat tattagtaat aatcttttca
    23821 ggaaggacgc tggctgttgc agtaatcatt ccaaattgtt ccattaaata tcctcactta
    23881 tagtcttgca agaagtcgtg caagtttttc agtgcatcca gcaaggcatg ctgttcctcc
    23941 gtagccattc cgtctaagat gttcttgacc atttcacgat gaaaatgctg atggacccga
    24001 aatagtaact ttcctttttt cgttagtccc aactttacaa cgcggcggtc atcttcactg
    24061 cggatacgtt cgacatagcc tttttttact aacttgttaa tagcagtggt caaggtccca
    24121 acagtaattg atagttcttt ggctacttct gaagttgttt ttttcttgta catcccgatt
    24181 gcctcgatcg tgtgcatctc tgtgattgac agatctttga attgagattt tttcagctca
    24241 gactcttcga ttgtcaaaat atcattgaag acactaacaa gataatcatt tactgttttt
    24301 aaatctggtt ccatgttcca ccgtccacta attagtttga ttatcaaatc ttttgatgtt
    24361 caaactatat cttaactttt ttcaaaatgc aaacttaaaa gatcattttt ttactatatg
    24421 agcttttttt aagattttac tcatttaaaa caactgataa atcagcattt ataatttctt
    24481 ttattagaaa aatcatctat ctcacatatt ttgattatca aagtattttc tgtgaacaga
    24541 actatagaat tccctaaaac ttgtccatta tttcaaaatt tgttatagtc tttttattca
    24601 aagcgtaaaa ggagatccta tgttaaaaga aaaaatgaaa actctcccca tgctgccggg
    24661 tgtctatctt atgaaagacc gagatggtaa ggtcatctat gttggtaaag caaaacggct
    24721 caaaaataga gtaagcagct attttcatca gaataaacag cattcaaaaa aagtattacg
    24781 tatgattcat catataacag attttgattt cgtcgtagta gacacggaat tagatgcttt
    24841 attgctcgag tgtcaattga tccaacatta ccgtcctttt tataaccgac aaatgaatta
    24901 tttcagtaat tataattatg tacatattac caataaggga tttgtattaa cagatactcc
    24961 tacggctcga acatacgggc cttttcgtct ctataaaaaa atgccgtcta ttttgcgtat
    25021 aatggaagaa acttatcaaa tgccttggtt gtctgaaatt agtttgttag ctttgcgagt
    25081 ccagcttcct gacctacagg aaatgacttt tgaacagaaa aaaaaggaac tccaagggct
    25141 gtttcaaggc cgaaataaaa agctactgac ttacttgaaa aaaagacaac aacatttcat
    25201 ctatcagttg aatttcgaaa aagccggtat gcttcaaaaa gatatcgaat tagttactta
    25261 ttttattaga cggatccagg aacaaaagca gtttttaaga acaccatcgc tcaccttcag
    25321 catgccatta gcagcagatg agagtcagaa aaagcactac ctcgtttgtt atggtcaact
    25381 tgcagaaaca atgattacct ctggtgacgt ttctcctgac ttctattatg aaaagaaaga
    25441 agctcattta tctttgaaac gtcaattgtc aaaagaagaa atcgatcctg tacaaatctt
    25501 gatcagttac cgcaaaaaat tagaaaaaga acagtttgaa attgaactgt taaacaaaaa
    25561 agaagctgaa aagcaactaa attagttgct tctcggcttc ttttaggcat cttcaacttc
    25621 aaatgtcaat tatcctaaaa tttattggat taagtcatag atttccatcg ctacgatatc
    25681 gatattatca aattcgtatt gctgatgagt atctgtttca gttaattcaa atgtatcggt
    25741 cgctttatca taagttactg tacacttctc tacgccttct ttttcaaaac ggcgaacttg
    25801 cagttcatta tctgctgact cgaccatagc ctccagtcgt tttatgattg cgactaattg
    25861 tgaatgtgtc atcggaggtc ctccttttct tatttctgtt atattgtatc aaaagcatag
    25921 cctacttgca ttgattttct ctaaaaaaac tcgtttttta tgattttttt tctggtattt
    25981 ttccttcagg ccaccaaagt ttgatcaaag cttgggttcc gtcattctca aaacctttat
    26041 ctgccaactc ttcatatagt ttcaatgctt gggtagttgc tggcaataca agatccattt
    26101 tttctgcttc ttctaatgca atctttaaat ctttgataaa atgtttgaca aaaaaaccag
    26161 gtgtgtaatc ttcttttaaa atacgaggag aataattgct taaagaccag ttagctgcac
    26221 ttccacctga aagcgtctca atcactttct ttaaatcaag tccgtttttt tgtgcataga
    26281 caagcatttc cgtcattcct gtcatcgtac ctgcaatcat gatctgatta gccatttttg
    26341 tatgctgacc tttcccagca gaaccatgca atgtaaatgt cgtaccaaat tctttgaata
    26401 aaggcagtac ttgatcataa acggcttctt ctccaccgac catgatcgtc agtgtaccat
    26461 tctttgctcc taagtcacca ccggataccg gtgcatctaa cgcatctgcg cctttttctt
    26521 ttgctgtttt tgcaattttt tctgccaggc ttggtgtact tgtagtcaaa tcaactaaaa
    26581 tatgtcctga gatatctgca gaaaaaatcc ccgactgtcc atagtagatt tcttctacat
    26641 ctttggggta acctaccatt gtaaagagaa tattactttg ttctgctacc gcttttggtg
    26701 tatctgccca gatagctcct tctgttacta aaggatcagc ttttgctttt gtccgattat
    26761 agacagctac ttcgtgtcct gcttctagta gatggcgtgc gacagcactt cccatgacgc
    26821 ctgttccgat aaaaccaagt ttcatttttt cgacctccta aaaatcaaaa atccttgctt
    26881 ctatgctagt atacgctaga aacaaggatt ttttcataaa aaatgtttga attttatctt
    26941 ttaaatgaat ttaattttat tttgattcgt tcaatcgagt cttcttcttc ttttcttcgc
    27001 atctcttctt catgataaac aaccatgtct tgataaaatt cgatcatagc ttcgccgaaa
    27061 tgtgtagatg aaatatcata aagtttagct tctaaaactt ttggatcttt aggaacttca
    27121 ctggaaatat aatcaataag tgctggtgca aagtcttcgt cggtttcaaa agttttccct
    27181 aatgaaggat gatcgaacaa tcggttcaaa taagcatttc cttccacgac acaaggtgtt
    27241 ccggctgcca tcgcttctgt ataagtaagc ccttgtgttt ctgaagtaga agcactgaca
    27301 aaataatctg ccgctttata ataaagtgct acatcattgt tgtccacttc tcctgtgaac
    27361 tgcacaaatt cttctaactg cagttctgag atcaattcct ctaactcttc tacataaggt
    27421 ccttttccta cgataactaa tctggcgtta ggataagcgg agatgacctg aggaaaccca
    27481 ttaatcaagg cttggatatt tttctcataa gaaatcctgc ttaaagaaag aatcatcaaa
    27541 tggttttcct gaagacctag tgactccctt aatttgctga tatcctgctg agtgatatca
    27601 gaacgtttga atttttcaat gtcgatacca gtaggaatca cgcgaagcgg tgctattaca
    27661 ccatagctgc gtaatgtatc aataacacgt tcacttggac aaactacacc tgtcgtatga
    27721 tttgcaaata atctagacaa gtattttaca tgggattgcc tgatcacttt tcctttaccg
    27781 atataatgaa ggtagtcttc atacatcgta tggtaagtat ggatcagagg tattttcaac
    27841 ttcttagcta ccatcttccc aagtatccct gctccgaatt ctgtatgggt atgaataaga
    27901 tctagttcta gttctttggc aaccaaataa gcataccaca tgcctctaac aacaactctt
    27961 cgatccttga aagaaataaa tggtacactt ggcattcgaa tcacatcttt ttccaactta
    28021 tccgcattag gatcggtcgt tgtaaaaata tagacttcat gcccatgtct ttctaattct
    28081 tgttttaatg ttttgatcga tgtagcaact ccgctgactt gcggaaagta ggtatcggta
    28141 aaaaagccga ttttcatgtt tttcgcctcc aaactagtcc ttgacctgat ttactttttt
    28201 taatttgcta gagacttttt cattcagtac actttcgtat acatttttaa gttcttcacc
    28261 gattttattg atacttcgct cttttgctgt ttgataaccg gcttgtgtcg tactcggtag
    28321 ttcttgattg gtaatctgtt ggatcagtcg gataaattct tcgtttgtct tccccatata
    28381 gcagttcttg ctatcttcta accagccatt atacactgga atatctcgaa caagtacgtt
    28441 ttgtttgctt gctaaagctt ctaaaacaac gatcccttct gtctcttcat aagaagggaa
    28501 aaagaataga tctgcacctg aatacgcacc ttctatgatc tctccacgaa tgtaaccagg
    28561 aaacaggaca ttttcaggat gatcttcttt tacaattttc cggatgttcc gaggaatcga
    28621 gtacatggga acatgaccaa accaaataaa tgtgtattcg ggcatcttct tagcaatttc
    28681 tacgaaatca atgattcctt tacgttcgaa aaacaaaccg acacaaatga ttactttttg
    28741 atccggagac agtttgaaat attctctgaa cttttgttct ttcattggat cagggtgata
    28801 tttctctaag tcgatcccat tggaaatagc ttgaatcggc acacggatac catagctttc
    28861 caacaactgt tttgaataag gtgttggcgt gatcagatag tccgcttttt ggtacaatcc
    28921 taccagatat ttttttacga taggagaaag ctggttcgat ccgataaagg aatttcggaa
    28981 atcttcctct gtagaatgcg catgatagac aacttttttt ccttctcttc tggctttatt
    29041 gaccatatta tgactattga ttccgtatgt attgatgtgc aggatgtcat aatcttcttt
    29101 ttcatctagt gtataagaga taccgacttc cgtcagagca cgtttttgat gatcaagcgc
    29161 acgcccgatt ccagattttg caagcatctt ttcactttca aaatataata ataccttcac
    29221 cttacgtccc ccttcactta tatagtataa catagcctac aaactgtcac tcaaacttaa
    29281 gccctatttt tgtctattct tactgacaaa aacgttttct taaaaaagaa caaaaaaact
    29341 ggcgtagctc ttttacaagc cacaccagct tttgatacgt tgtttatttt acatattcat
    29401 gaacaagttc aacgacttct tccatcgtat cgcattcttt caatgcacga tcagcaagtt
    29461 cagccatttt cgctgtgtcc aagcgtttca ttaaaccacg cgttttaaga atagatgtcg
    29521 cactcattga gaactcatct agacccatac ctactagcaa tggaacagct gtttgatctc
    29581 cagccatttc tccacacata cctgcccatt ttccttcagc gtgtgctgca tcaattacat
    29641 ttttgatcaa acgtaaaatt gatgggttat atggttggta caagtaagaa acgcgttcgt
    29701 tcatacggtc tgctgccatt gtgtattgaa tcaaatcgtt cgtacctaca gagaagaaat
    29761 ctacttcttt tgcaaacttg tctgctaaga ctgctgctgc tggaatctcg atcatgatgc
    29821 cgacttggat cgtatcagat acttccttgc cttcacttat caatttttgt ttttcttctt
    29881 caaagatcgc ttttgctgcg cggaattctt tgagtgtagc taccataggg aacatgatac
    29941 gtaaattacc atgaacagat gcacgaagca atgcacgcat ttgtgtacgg aacatttcgt
    30001 cgccttgttc agataaactg atacgcaatg cacgatatcc taagaatgga ttcatttcat
    30061 gaggtaattg cagatatggt agttctttat ctccaccgat gtccattgta cgaacaacta
    30121 caggttttcc ttccatacct tctaatacag ctttgtaagc ttcatattgg tcatcttctg
    30181 ttgggaagtc tggagaatcc atatacagga attcagtacg gtacagacca actgcttctc
    30241 caccattatt atggacacca actagatctt ttggtgttcc gatgtttgca gctaattcaa
    30301 aatgcttgcc gtcagctgtg acagtttctg cattttttaa tttttcccat tctgcttttt
    30361 gtgctgcgta atctgcacct gctttttcaa attcagcttt ttgttcatct gtaggatcga
    30421 tgattacatc gccttcgatc ccgttgacag ccaaaatatc gccttctttg actttagcag
    30481 taatttcttt tgtcccaacg attgctggaa tttctaaaga acgtgccatg atagcagaat
    30541 gtgaagtacg tccaccaatg tctgttacaa acgcttttac aaaattgcga tctaattgtg
    30601 ctgtatcact tggagtcaag tcatgtgcaa caacgaccac ttcttcgttg atcattgatg
    30661 gatttggtaa agtaacgcct aataagtgcg ctaaaatacg tttagcaacg tcacgaatat
    30721 ctgcagcacg ctcttgcata taagcattat cttccattgc ttcgaacata ccgatataca
    30781 tatccgttac ttcttttagc gctgattcag catttacgct gttgtcttta atattttgct
    30841 tgatttgacc taccatttct ggatctgaaa gaaccatcaa atgggcatca aatacttgcg
    30901 cttctgcttc acctaagctt tgcgctgctt tttcacgaat ttgctgcaat tcttcagtag
    30961 atttagctaa tgcagcatcc aaacgagctt cttcagccgc agtatcttct actgttgcct
    31021 tactgaatgt taaatccggt tgaactagca ggtaagcttt tgcaacggct acaccgtcac
    31081 tagcggcaat cccttttagc atttcaacca ttattcagat aagccttctt tcttcattgt
    31141 ttcaacgatt gctgccattg catcagcttc gtcagcacct tctgcagtaa tagtaacatc
    31201 agaaccttga cctacaccta aagacataac gcccatgatt gatttcaagt ttactgattt
    31261 acctttatac tctaagttta catcagagtt aaatttgctt gctgtttgta ctaatagtgt
    31321 agctggacga gcgtggatcc cagtttctgc tactacgtga aattctttct tttccatatt
    31381 aatcggtctc ctttaagtga gtgttgtttt tatgtgaggg ttttcttttt tagtaattca
    31441 gagaatccta acaaatgcca ccctttcatc tgtaaagatt aacatttttt ttcgttagat
    31501 acaacagttt tcattcaatt tcagataaaa gtattcaaat tattccggat tctttttcat
    31561 ccttttcttc acattttata acaaacgtgt ttatttcctt tttcttgtcg ctttctcttc
    31621 tcctgacgtt tatcattctt tcctttgacc ctctttgttt tcatatgaaa cgaattactt
    31681 gcttcccttt ttatttttag tataataaga gtcaaaggtc aggaatggtc aatagagatt
    31741 tcaccttttc tacctcataa atctcttaaa aaactagggg ttattctttt acctcatgaa
    31801 aaacgagatg taaaatatgg atgtacccat ttttgtgaaa ggacgtgaat gattcatgct
    31861 ttgtcaaaac tgcggcaaga atgaggcaac gattcacttg tatgccactg tcaatggtca
    31921 gcggacacaa ctcgattact gtcagagctg ttatcaaaaa atcaaaaatc aacaaaatgg
    31981 aggtctgact aatatggccc aaaatgatcc atttggattt ggcagtttgg acgatctttt
    32041 ccgttccatg tctcgccaaa tgcaacagca aggaaattat gagcaaacac caccaacaca
    32101 atttggcgga aacaacaact tcaatggtgg tcagccacct caaggcaata cagaaggttt
    32161 attgggagaa tacggaatca atatcacaga acaagcacga caaggtgata tcgatcctgt
    32221 gatcggacgc gatgacgaaa tcaaacgagt cattgaaatt ttaaatcgcc gaaccaagaa
    32281 caatcctgtc ttgattggag aaccaggtgt tggtaaaaca gcagttgttg aaggtttagc
    32341 acaaaaaatc gtagatggtg atgtaccgca aaaattaatg gacaaagaag tcattcgttt
    32401 agatgtcgta tctttagtcc aaggtactgg tatacgagga caatttgaag aacgtatgca
    32461 aaaattgatt gaagagatcc gtcaagcaga aaatgtgatc ctattcatag atgaagttca
    32521 cgaaatagtc ggtgctggtt ctgctggtga tggaaatatg gatgctggta atattttaaa
    32581 accagcttta gctcgaggag aattgcaaat ggttggtgct actaccttaa atgagtaccg
    32641 catcatcgaa aaagacgctg ctttagaacg tcgtatgcaa cctgtacggg tagatgaacc
    32701 aactgtcgaa gaaacgatca gtattttgaa aggtttgcaa aaacgttatg aagactatca
    32761 tcatgtaaaa tatactgatg aggccatcga agcagccgca actttatcca atcgttacgt
    32821 ccaagatcgc ttcttgccgg ataaagccat cgatttgcta gatgaaacag gttctaagaa
    32881 aaacttgacg atccaaatcg ttgatcctaa aacaatcgag aaaaaactgc aagaagcaga
    32941 agaacaaaaa gttttagctt ctcgagaaga agatttcgaa aaagcagctt attatcgcga
    33001 tcagatcaat aaacttcaaa aaatgaaaga acgtcagctc actgaagagg aaacacctgt
    33061 gattaccgaa aaagatatgg aaaaaatcgt tgaacaacgg acaggtattc cagtgggtga
    33121 attaaaagaa aaagaacaga cacaactgaa aaacttagca gatgacttga aagctcatgt
    33181 catcggacaa gataacgctg tagatcgagt agcgaaagcg attcgccgaa accgtgttgg
    33241 attaaacaaa cagaatcgtc caatcggctc cttcttattt gttggaccaa ctggtgtagg
    33301 taaaacagag cttgcgaaac aacttgccta cgaactattc ggttcacaag attcaatgat
    33361 tcgtttcgat atgtctgaat atatggaaaa acatagtgtc tctaaattga ttggttctcc
    33421 tccaggttat gtcggatacg aagaagctgg tcaattaaca gaaaaagtac ggagaaatcc
    33481 ttacagtctt gtcttgttag atgaagtaga aaaagctcat ccagatgttt tgcatatgtt
    33541 cttgcaaatc ttagatgatg gtcgattgac agatgcacaa ggaagaacgg tcagctttaa
    33601 agatacgatc atcattatga caagtaatgc cggaactggt aaagtagaag caaacgttgg
    33661 ttttggtgcg gcacgcgaag gtgttactcg ttctgtattg aaccaattaa acaactactt
    33721 tacaccagaa tttctgaacc gttttgacgg gatcatcgaa ttcagtgcat tatcaaaaga
    33781 aaacttgatg acaatcgtca cactaatgct agacgatgtc aaccaaatgc tggcagcaca
    33841 gcaacttcac atcgaagttc ctacgaatgt caaagaaaaa ttagttgact taggctatga
    33901 tccatctatg ggtgctcgtc ctcttcgacg cacgatccaa gaacaaatcg aagatggtat
    33961 cgctgaattt tatcttgatc acccttctat ccatgagttg aaagcaaaac tggataaaga
    34021 tggaaaaatc atcgttactt ctaaaccaga acgtttggct aaagaatcag ccgaagaaac
    34081 ggctgaataa atccagtttt atagcgtgag acggtatttc tttgagaaat gccgtctcat
    34141 tcttttttca gaaaagtcaa aatactgttc attttataaa aaagaaatta taataagaga
    34201 aacaagcaat taaaaataca taaaagaggt gagcgccatg aaattggtaa atgtaacaaa
    34261 cagccattcc cgtcttgtat taaaccagct tgaaaacact gatgcccatc tagtcaaggt
    34321 ctacacagcc ggaaatacca ctattgtcta cactgaagcc cctcaacata atgaaattct
    34381 gctgatcaat gacaaacgta aaatccagcc gaaagaaatc gaagatgcta aaaattattt
    34441 cttagataaa atcaaagacg ccgtttacca cgaggatgaa atcaaagtaa tcgaattggc
    34501 aggccttgtt gaaatctcga ttccaaaaca tgaattaggc gctacattag ccgtgtaaac
    34561 aaattttgaa cataataatt aaagagcgtg ggacaaaagt aaa
//
LOCUS       DAZKCW010000029        32048 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000029 DAZKCW010000000
VERSION     DAZKCW010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.029"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..245
                     /locus_tag="ACG84Z_001543"
     CDS             6..245
                     /locus_tag="ACG84Z_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162394.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            312..521
                     /locus_tag="ACG84Z_001544"
     CDS             312..521
                     /locus_tag="ACG84Z_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162395.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            581..1252
                     /locus_tag="ACG84Z_001545"
     CDS             581..1252
                     /locus_tag="ACG84Z_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFP9162396.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1305..3281
                     /locus_tag="ACG84Z_001546"
     CDS             1305..3281
                     /locus_tag="ACG84Z_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFP9162397.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGGLSAVVYFKKKA"
     gene            3294..4049
                     /locus_tag="ACG84Z_001547"
     CDS             3294..4049
                     /locus_tag="ACG84Z_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9162398.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            4046..4870
                     /locus_tag="ACG84Z_001548"
     CDS             4046..4870
                     /locus_tag="ACG84Z_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFP9162399.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQSVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            4880..5128
                     /locus_tag="ACG84Z_001549"
     CDS             4880..5128
                     /locus_tag="ACG84Z_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162400.1"
                     /translation="MKIIRILVFNLSFLAATILCCGLIFSQLSIYPRYQRLFIHFLNI
                     QCASMPLEVIKKLLINPIFMVSLVLLTGLVTWVLGKKE"
     gene            5171..7270
                     /locus_tag="ACG84Z_001550"
     CDS             5171..7270
                     /locus_tag="ACG84Z_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFP9162401.1"
                     /translation="MENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSFLANA
                     ANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNTVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQDPVED
                     RLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(7308..9365)
                     /locus_tag="ACG84Z_001551"
     CDS             complement(7308..9365)
                     /locus_tag="ACG84Z_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFP9162402.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(9479..9691)
                     /locus_tag="ACG84Z_001552"
     CDS             complement(9479..9691)
                     /locus_tag="ACG84Z_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162403.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            9878..10345
                     /locus_tag="ACG84Z_001553"
     CDS             9878..10345
                     /locus_tag="ACG84Z_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162404.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            10342..10584
                     /locus_tag="ACG84Z_001554"
     CDS             10342..10584
                     /locus_tag="ACG84Z_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HFP9162405.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            10602..10904
                     /locus_tag="ACG84Z_001555"
     CDS             10602..10904
                     /locus_tag="ACG84Z_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162406.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            10976..13030
                     /locus_tag="ACG84Z_001556"
     CDS             10976..13030
                     /locus_tag="ACG84Z_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162407.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLIDLIR
                     LDVFKDTDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETDEVEVDPVEA
                     NEESTWTEGDFQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKVKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            13030..15642
                     /locus_tag="ACG84Z_001557"
     CDS             13030..15642
                     /locus_tag="ACG84Z_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFP9162408.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFSEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            15639..18170
                     /locus_tag="ACG84Z_001558"
     CDS             15639..18170
                     /locus_tag="ACG84Z_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFP9162409.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PEQAKGMAGNDKSGLSDIQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEDKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            18222..18554
                     /locus_tag="ACG84Z_001559"
     CDS             18222..18554
                     /locus_tag="ACG84Z_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162410.1"
                     /translation="MDKYSNMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            18555..19148
                     /locus_tag="ACG84Z_001560"
     CDS             18555..19148
                     /locus_tag="ACG84Z_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162411.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            19311..21005
                     /locus_tag="ACG84Z_001561"
     CDS             19311..21005
                     /locus_tag="ACG84Z_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFP9162412.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEIVKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            21693..23570
                     /gene="ltrA"
                     /locus_tag="ACG84Z_001562"
     CDS             21693..23570
                     /gene="ltrA"
                     /locus_tag="ACG84Z_001562"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFP9162413.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            23701..24078
                     /locus_tag="ACG84Z_001563"
                     /pseudo
     CDS             23701..24078
                     /locus_tag="ACG84Z_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            24078..25283
                     /locus_tag="ACG84Z_001564"
     CDS             24078..25283
                     /locus_tag="ACG84Z_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFP9162414.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMS
                     IINTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            25299..25943
                     /locus_tag="ACG84Z_001565"
     CDS             25299..25943
                     /locus_tag="ACG84Z_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162415.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            25954..26760
                     /locus_tag="ACG84Z_001566"
     CDS             25954..26760
                     /locus_tag="ACG84Z_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162416.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            26782..27011
                     /locus_tag="ACG84Z_001567"
                     /pseudo
     CDS             26782..27011
                     /locus_tag="ACG84Z_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27557..27832
                     /locus_tag="ACG84Z_001568"
     CDS             27557..27832
                     /locus_tag="ACG84Z_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162417.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            27874..28296
                     /locus_tag="ACG84Z_001569"
     CDS             27874..28296
                     /locus_tag="ACG84Z_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162418.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            28315..29907
                     /gene="mobP2"
                     /locus_tag="ACG84Z_001570"
     CDS             28315..29907
                     /gene="mobP2"
                     /locus_tag="ACG84Z_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFP9162419.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            29919..30254
                     /locus_tag="ACG84Z_001571"
     CDS             29919..30254
                     /locus_tag="ACG84Z_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162420.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            30401..30595
                     /locus_tag="ACG84Z_001572"
     CDS             30401..30595
                     /locus_tag="ACG84Z_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162421.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            30627..>32048
                     /locus_tag="ACG84Z_001573"
     CDS             30627..>32048
                     /locus_tag="ACG84Z_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFP9162422.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKK"
BASE COUNT        11834 a         4966 c         6548 g         8700 t
ORIGIN      
        1 agtagatggc gcgaccagtt ttagaggcga tggatatgga tactttgaca aaaggaaggt
       61 atgtacagct gttagctcgt ggttattcac ctaaagaagt attcaaagcc ttatctaaag
      121 gaacagatat ggaaaaagaa agattgcgaa aagaattcga ttattggaga acccataatg
      181 gaatcaagga tttgaaacca gcacggccag taattaaacg aaagaaaaag ataacccaag
      241 actgaagtgt agagcgtatg tgatcatagg cttttttatt tttgcaaaaa acaaggaagg
      301 taggaaaact catgaattat gaagaaatcg aaaacagaaa aaaagtgtcg aaagaaatgg
      361 aagaaaagtt actaaaaacg atgaagcaaa aacaccttaa aagattatct gtcgcgcaat
      421 atatcaatga tatgcagtta acaggaaaag agaaagcttg tttgttaggt tcaatgaaaa
      481 actttgaaca gttgagacga acttatagaa ttcattttta aaactttttc tatggaaatg
      541 agaaaaagtt tttttgtttt gtctgaaagg aggcagatgg atgaaaaaat ggttatttgg
      601 ttttttagga gtcactttaa tcgtcttttg cagtgtgttt ggctatgtta gctaccaaaa
      661 acatgaagga gaggtgttta agcaaaatat agaaaaaaag atgcccgtag atcaaatcaa
      721 tgcacatgca aagagttata aggaggatgc aacgaacgtc aataatgata tgtctttggg
      781 gcaaatgttg tccatacaaa aagaagcaat cgaaatgggc gtcaataaac aagtatttgc
      841 acaaattcag attcctgcac ttggtttagc attgccaatt tttaaagggg caaatcaata
      901 cactttgagt cttggagcgg ctacttattt ttatgaagat gccgaaatgg gcaaaggaaa
      961 ctatgtccta gcaggtcata acatggaaat gccaggtgtt ttattttctg atattcaaaa
     1021 gttgtcatta ggggaggtga tggacttagt tagtaacgat ggcgtctatc gttacaaggt
     1081 aacgcgtaaa tttatcgtac ctgggtactt taaattaatc gatggcgttc ctgaagagaa
     1141 ctctttcttg tctttgccaa agaaaggaga gaaaccctta ttaacgttgt ttacttgtgt
     1201 ttatacgtca caaggaaaag aaagatacgt ggtacaggga gagctacaat aacaaggttt
     1261 taatcaacgc gagtcgttga aatatgaaat gaggagagta aaaaatggca ataaatcggt
     1321 atgtaaaaaa agctggaatg cttgttggaa tgttaggaat cattgcaggc tgctttcagg
     1381 ggtatcaagt acatgcagaa gatgtcacgc aaaaaacacc accagagaag gtcaatatca
     1441 cggttcataa attaatgtac gatcaaggaa cgcaattgaa tgttgatatt gacgggatca
     1501 aaaacgatgg ttatacgcac gatcaatatc ctacaggtgt aacgaaatac aacaaggcag
     1561 attatggtga tgttgagttt acgttaggaa atattacgga tcaagtatta ccgagagaag
     1621 attctgatct aaccaacgcg aaagtggacg agattgtaca agatgtagaa gacaagggat
     1681 ctaacagtga gtacgtcaag aatgcaacca acaaaattac ttcagctgta gatgaaaatg
     1741 gtgagatcac ttttactgat caaccagcct atgtcaattc caaagggaat gtatatgtgg
     1801 tttatgaaag taaatccgct gctggattag tcacacaaaa agcaaaacca atggttgtga
     1861 ttgcgccaat gacagataaa acaggatcag gatttttaaa aaatattcat ttgtatccta
     1921 agaacattgt ttctaagttg agttttgaat taacgaaatt tggtgacgat ggcgcagacc
     1981 aaagcaaaca aaccctttta aaaggggcaa aatttgagtt atacaagggc gaacctggaa
     2041 aaggaacaaa attgggtgat cttgtatcgg atgatcaagg aaagctgact gcgactgatt
     2101 tgacgttagg aaaatactat tttgtggaag ttccttcgga agttgtagtg ggatcagatc
     2161 aagaaccaac agcagatcaa tatttattag gcgcagacgc tcgcaacgat gcgcacaata
     2221 aattaacctt tgaaattacg aatgatggcg tgacaagtga cttaaaagct tcatacgtaa
     2281 actataaagc accagtgatc gataaaacag taacaaatgg aacaggacaa gaacattctt
     2341 tccaaattgg tgacgcagta aattatcaag gaacgattca tattccaaca gacattgcag
     2401 gtggcgcaga cggtatcaca gtaaacggtg tgaaaagcga aacttctcct tacagtgtat
     2461 ttaaatgggg agatacagca ggtaaaggac tttcttatgt tgctgaaaaa gcagatatta
     2521 aagtaacaaa taatgatggt tcagtcgtat taaaagaaaa tactgactat aaaatcgaaa
     2581 attctgatag tggttttgtg atcgatttta tcgtaaataa tggacaagta agtgatacag
     2641 ttgcgaattt acatggtcaa gatctaaaaa tgacttataa catgtttgtg aatgatagtg
     2701 ctgaaatcgc aaatccatta acaaatagcg tggatttcgt ttataacaat aatccattta
     2761 atcaggaaga acaccacgaa aaaacgaaag ctgacgttgt gacttatggc gcaaaattct
     2821 taaaagtcga tagcggccta tttggaacag gtatcaaagc aacaccgctt gaaggcgcag
     2881 aatttgcagc taagaatgca gaaggtaagt actacggtgg acttactgat acagataaag
     2941 atggtgtcaa agaagcagtt tgggtagacg atgtagcaaa tgcagcaatc ctaaaatcag
     3001 ataaagaggg tcattttgaa atcactggtt taactgaagg agattactca ctggaagaaa
     3061 caaaagctcc tgaaaactat caaaaattaa caaaagagat ctctttcaaa gtagacaaag
     3121 attcatacaa agaagaaaac cgaatcacga tcaaaaataa tcaaaaagct tccgtaccaa
     3181 tgactggtag caacggtttc caatcttacg tattgatctc ttgcttgttg ctaggagcag
     3241 ggggactttc tgcagttgtt tactttaaga agaaagccta gaaggatcag ctaatgatta
     3301 ttcgtaagcc cccaaaaaga agagtcatgc acaaactgat gatatttttt tggttgctgt
     3361 cggcagtagc agtctattta attccagttg tggaaacaaa tgtagcgaaa tttcaacaac
     3421 agcaaagaat tttagccatt gaaaatcttg aaaaaacaga ttcttctttg gatgttgcga
     3481 aaatagagtt aggcgatcct gttggtgttc ttacaattcc aagtatttct ttaaaactac
     3541 caatttatga cggaacttcc gacaaaattt tagagaatgg tgtagggatt acggaaggaa
     3601 ctggcgatat tacaggagga aacggtaaaa atcctttaat cgcggggcac agtggacttt
     3661 ataaagataa tcttttcgat gatttgcctt cagtaaaaaa agggcaaaaa ttctttatta
     3721 aggtaaatga agaacaacat gcctatcaaa tttatcgaat tgaagaagtt aaagcagaag
     3781 aattacaaaa aaattattta gattatctta tgcctgaaaa agaccaagat aggatcacgt
     3841 taatgacatg cacaccaaaa ggtgtcaact cacaccgctt tttagtgtat ggtgaacgag
     3901 tttccttcag taaagaagat ttaaaactac agaaaaaagc aaaaaatagg aaatcaattt
     3961 cattggattg gcgattagca ctgctattcg cttttttttg cgttcctatt atttttattt
     4021 ataaaaaaat aaggaggaga tcggaatgaa taagagaaaa tggctgtttg tttgtgtagc
     4081 agctctcttt tctactgtag cttattcgca actgtctttc gctgacagca gtgatagtag
     4141 taccactcaa acaatagata attcaattac tgcaccaagc gaaacggaca gttcggagaa
     4201 tactacagaa gaaacggcag attcaaatat aagctttact gaatcaacga atccaacgtc
     4261 agaaagttct tcagagactt cagaaaagcc gcaagacgta gaagatacgc aagtgatcaa
     4321 gcaagccatt catattcaaa aaattatttc ttcgaatcaa atcaacaatc aaggcagtca
     4381 agtagcccag caagaaggta tcaatggcgc gaagtttatt gtctacgata tcacgaatat
     4441 cttagaagaa atgtcacaag atgataatga gaaaaatcaa tctgtagaaa taattgagtc
     4501 aaaattgaaa gatcgagcaa aaaaactttc atacgaccag ttgaaaaaag tggctgaagg
     4561 agaaaccaaa acgattgatg atcaggaagg cgtgattgaa ttttccattg aagtacctgc
     4621 aaacaaaaaa caagcatact atatcgttaa tgaatcaagc cctgaaaaca tttcaaacag
     4681 tgaagatatt gttttattga cacctgtttc aaatgaaaaa ggtgaatttt tgacggatgt
     4741 ttggttatac cctaaatcag agaaatcaga gccgaaagaa gaaattaaaa aagttgtgtc
     4801 aactggtgta aagaagaact tttttgaaaa ttgttgggaa ttttttgctc aattattttt
     4861 tgataattag gatgaaatga tgaaaataat aagaatatta gtttttaatc tatccttttt
     4921 agccgcaaca atattgtgtt gcggtttaat tttttctcaa ttatcaattt atccaagata
     4981 tcaacgattg ttcattcatt ttctaaacat tcaatgtgct tccatgccat tagaggtgat
     5041 taaaaagctc ttgatcaatc caatttttat ggttagtttg gttcttctta caggattggt
     5101 aacgtgggta ttaggaaaaa aagaatgaaa agcttacgat cgtttaaaaa aatattagat
     5161 ggagggcatt atggaaaata aaattcattg cactacggga agagtaatta ctttagtgtt
     5221 gtttttgttc cttcttcttt ttgcgagggg aactgcagtc caggccttag aaaaagttga
     5281 tccgagtcaa atcaaagaaa ataataatct ggtgctttat catgatagtg attcattgag
     5341 aaatatcgaa gtaactggga tcaatggatt taagatacta gatgagtatt caactaaaaa
     5401 acaaaaagta cttgcttggc caaaagtcaa agatttgaaa agtacgtcaa aaatcgttgc
     5461 ccattatcaa aaagtaggta cttatctagg aaaagaaatt gattgtgacg tgactttttc
     5521 taattttgta gcgcacgctg gggttaacca agacggatta gctaaaacaa ttaatggcaa
     5581 aaagtattat aattatttgc tctttgataa aaatatttat cgaggatttt tcatgcagtc
     5641 aatcaatgtc atgaatgcaa aactagaatt taagtatgca ggaacaaaaa caaaagtagc
     5701 tttgagtgaa ccacagccag aaattcaatc aaaaatgaga tcgatgagag cagctggtat
     5761 tgatttaaac gatacatttc tatccattta cagtttaaat ggacagtatc agcaacgtgt
     5821 gtcttggtat aatgacaata atgaatctgt cggtgaacgt aatattgata tgagagaatt
     5881 tgttgggtat gaaaaaatgg gtagcttacc ttattttgtc acaacagata cagcatgtgc
     5941 agaatacaaa gctcctgcgt tatcaacaaa caatttaact tcaaaagtag tgggaggacg
     6001 tgcagaaaag gcttatagct cgaatgatca tttcaccgat gttgtaggag ctgatactta
     6061 tcacagaagt ggtgtaacgt atacgcttca aggcgcttcc ccaacattca tgattggcgc
     6121 aaatacgaat agtatgatgt ttagctttga tactgcattg ctatggacac cacaaccatc
     6181 gaagcctaca aaagaagtgt ttaacaaagc taatactgaa gaggcagcac acaatattga
     6241 caaaaaagtg attccacaag gatcagatgt ttactatcat attcaccaaa agtttgatgc
     6301 attaacagtc aacacaatga acaaatacaa atcatttaaa atcactgata cctttgacag
     6361 caaaaatttt gatatggtat cggatgggaa aaactatgat ggcgcattgt ggtatgttga
     6421 agcgaatggt acttggaaaa aagctgatac aggaggaaag ttaactgtat caggtaatac
     6481 agtcacttat actgcttctg acagcttttt agctaacgct gcaaattacg gtagggatta
     6541 tattttgcag ctccatatga gagcaaaaaa tgatgcaaaa ggaattgcac caaatgtggc
     6601 tactgtaacg tttaacaatg atccgaacaa aggaacacaa aaaacaaata cagtagaaaa
     6661 ctatttctct cttaaaccaa ataaaaaagt ggaacaagat gggaaagatg ttgatggtcg
     6721 aaatgatggt aaaaaaggaa cgcctacagc tcctttaaat gcaggatctg aagtacaata
     6781 tctagtcaca caaaaatggc atacaaaagg tgtagacatt gcctcagatc attacaagca
     6841 atttagtatt caagatccag tggaagatcg tttgacgtat aaagaaggtt ctgcgcgagt
     6901 gatagatatg agtacaggaa aagatattac ttcagaaggt acactaacct atgatagcaa
     6961 ttcaagaacg ctgaagtggg aagcttccgc tgatttctta agtaaaaatc ttttagatgg
     7021 acgagaaatt cagctgatat ttacagctaa aactcctttg aatgaagaat tggatatcga
     7081 caaccaagca aaagtttcag tagaaagtat tgagaaagca actaatgtag taacgattgg
     7141 ggtaaaacct aacttacctc agatcattgt gccaaaaact ggatcgaatc atttagtgct
     7201 aactgttatt ggaagtatat tatttcttac tttagcatca ttgggctatg tagttttaaa
     7261 actcaaataa atataaaaac aaggctgaga atcagccttg ttttctttta tttgaagatt
     7321 ggattcgcac taataaatac attatctacg ccaattctac cagcagagtc aactacaaaa
     7381 ttatgaccta atccgagaat actttggtta ttataaagta aatttgcatt atgggcaggg
     7441 ctatttttcc atcctaccat ggcatcgata gcaccatcgt ctgataaaag gtcatcaata
     7501 tacagcccag tttgacttat gttttctccc ttagcaccgt agcagcctaa gctttccaat
     7561 aaatcttgga aagtaccacc accagggcga tagtgactga agctgacttg taattcttta
     7621 gctcgaatat ctgcagcctg ttgaacaata tcattgaatt gcattggggc aacaccattt
     7681 tgttggcgat aatcatttaa ccaagcaagt tctttttgac gcataaagtt acgtaattcg
     7741 tctaatgaaa tctttttata tttgaatgtg attgttttat tttgatcgac gttattaatg
     7801 gatcgttggc cgtttttatc cacggtaacg gtaggatcgt catttctgca caagaaataa
     7861 ttttgatcag tcatgttttt ccaaggagta gcaaagctat ccccttcgta tactgttttt
     7921 gattcactag agagaacagc gttggtatca gcatttacat gattaacagt cacattaaat
     7981 ttacgagtgt agttgaaaat ataattttga ctttcagtca cattgtttaa ggttactgaa
     8041 tttgttggtt ctacccgatc gtctaaaaca tatccttgaa tagaaggagc agttaaagtg
     8101 acactgtcac cgtgagtgac attgactatc tgttctttca aaatattaac tcgtccttcg
     8161 tttttgtagt tgttattgca caacaaattg atttgatgca cttgattata attgaatgtg
     8221 attgttgtat tacctgtgat tgttttgctt tgagtatcat taccaatcac tttgtagcta
     8281 aaattatctt tagcgccttc gctatattta aatgcttttg ccttagcagt gtaagtagaa
     8341 ccagaagtta cttttgcttg atctgtagca atcacttgac ctgtttgatt gtcaatatgg
     8401 ttaatagtaa ccgtatattc ttttggtgtt tcaggtttgt gttgcaaccc tttaaatgca
     8461 gcatcaagac tatttttagc attgtttact tgtgtttgag aaaccttaga atcgtctagt
     8521 acttttttag cattggataa agcagtctga aaattattcc aagattcttc tgtaaaatct
     8581 cctttagcag ttgattttac tcggttgtat aaagcttgta attcagcttt attcacagta
     8641 ggaactggtt ttttctttaa tcctttgtaa gcagaatcta atttattttt ggcactatcc
     8701 acttgctttt gagtcgcttt tgagtcattt aacactttct tagcattgtt taaagcggtt
     8761 tggaatgcgt tccaggtatt gtcggtatag tcaccttttt tcgttccctt aacgctcgta
     8821 taaagagctt ctagagccga tttattcact ttgggtttag aggtgtcagc gccataccaa
     8881 ccgatacctt cgtatttcca gccatagtct ttggttaacc attgtacttc tttccaactt
     8941 gcagtgtagt gatgtgagcc agattttaca ccaggaagga aaaggcggta gatcggttta
     9001 ttattttttt cggcagaacg ccaggcaggc ccttcataag tccagccgta atttttagtc
     9061 aaccatttca cttcatccca actagctgtg taatggtgat cacgaagacc tttattgtac
     9121 aaacgataga caagatggcc accgctagtc ggtgcttccc aggcggggcc ttcataattt
     9181 ccccatttta tctttactag atggtcacgt tcttttttgc tagaggtgta aaaatgttca
     9241 ttattatttg gattgtaaag gcgatacatg acgttagttg aagcagcgtc aacagatcca
     9301 gcaagactaa gtgaggcagc aaatgttcca atagctaaaa cagtttttgg attaaataat
     9361 ttcatttttt caactcctaa atttaattaa aaatgtttac atgattatta tatatcggct
     9421 aaccgatata gtcaataaaa aataagaaaa gccttatata attttggctt ttcttatttt
     9481 atttgttagt tgaagtatta atatcaacga tttcttcagc caatttattt aatttcatag
     9541 catttatgaa tctcatgttg tctatactag agcgtttgtt ggcaaggtca cttactgtag
     9601 ttaagggtac gccagattct atggatatag aacgaactga tttaccacta tcaaacagca
     9661 accattcgat tttcttttta tcagcgtaca tttcaatgct ccttcttgtt ttttctttat
     9721 tatagctctt ttttgtaatg aatcacaata tcaagagaaa aattttctat agaaaggtgg
     9781 atttttatga gtattcgttc tccgtgtatc caaatgaggt ttgttgctac tttcgttatt
     9841 tgatatacta aaaataaaca acgaaagaag gaataaaatg aagaaaaagc aactatggtt
     9901 tgtctctatg tttgcaatat tttttattat tttaagtgga tgttcaagta ataagaaatc
     9961 ggaagctaaa gaagataata gtttattgca accaggaact gtttggaaag aagaagtagg
    10021 tggtcttatt cataatttaa aaattataga tgatactacc tgggaatatt ctgaaagtgt
    10081 atggcatcca gatcctgtac aaataacagt taagaggcaa aaagactatg aaggtttaga
    10141 aagatacaaa atagtagatt ctgcaggcat tagggaattt ataaacaaac ctgattcatt
    10201 atttattgtt gttccctatg agaaggatgg cgtaaaaaaa ataatttttc ttggatctag
    10261 caaggatgag aagcgaacga aagagaaatt aattcatgat ggatcagagt taaataaata
    10321 caaattacaa aagactagtg agtgattgct agtcttttta tttatcctga aggaggaatc
    10381 acagtggcaa aagttaaaac accattcgaa aaagccgcgt ctaaaatctt agaacgccgt
    10441 ggtgtttctg aaatacagtg gaaaaaagaa gttcttgaaa aagcacaatt tgacctatta
    10501 cgaggaaaag ataaggactt agaagaatat atctatcaac gtgaacgtga aaaacttgta
    10561 ttcgatgaaa ttattaaaca ttaaaaggag cgaataatct tatgtttgaa tcaattacaa
    10621 tgaatttttt aactcaaccg aaagtagtag ctgcagttga tatttttaga gcattacaaa
    10681 ctgccgcaac tagtttgaaa aataatctga tgatttttgc tgctgttgcg gcagtggctt
    10741 ccattgctct tggaggtatt ttcttcttct ttgggcgaag aggagctgaa aacgggaaga
    10801 cacacgtagg ttatgtattg ttgggggtag gagttatttt agctgccgct tctattgtag
    10861 tttcaatgtt ctcaatgttt ggacaaaccc cacaaggact ataaaaaaaa caagtaggag
    10921 gagtaaaaag tacgtggcta ctttttactc ctttttttat gaaaggagaa tattcatgtt
    10981 ttttacgatt tcaggaaatg caaaattgga taaagagtta ataagaaaag caacgaagaa
    11041 agtgggaaag cgtacttcct ttttaccgaa aacaattaaa tattctgtca ttgaaacgga
    11101 agaacagcta catgtgttag gacaagtgtt agaacaagag aatcaatctt ctgttaaatt
    11161 gactctcacg ttacatgata aagaaggaaa aatagaaaag gctggcacag aatacgtttt
    11221 tggcccactg gattatcaaa tttcagaagg tttttatcct acattgatag atttaatccg
    11281 ccttgatgtg tttaaagata cggatgaaac tatgagtgtg gaagagtctt atcgaaacga
    11341 aaaactttta caagttttag aagaagagtt agagagcgac caaagaaaag tgaatcaagt
    11401 gagtgaagtc gaagtaaatg aagaagtacc atgggaacga ccaatctttc caaagaagga
    11461 gtcaaaagaa aaagagacag tctatgttga cgaacaagct gatattccga ctcagaaatc
    11521 gatatttgag gaagagaacg atgtgatggg tcaattggag gtagatccct ttgaagaaac
    11581 aatggaggat gaagagacgg acgaagtaga agttgatcca gttgaagcta atgaagagtc
    11641 aacatggact gaaggggatt ttcaggaata tattgaacca cttatcagtg aagaagtaga
    11701 aaaaaacgaa acagagatac aaaaggcaac tgtatttgat tatattttgg atcaatatcc
    11761 gccagagcat gaatggatga aagaaaaaaa caaattattt ttaaatgagc tttattcgaa
    11821 atatcaatta ccccaaacct atcaagcatt tttagagagt aaagaagaat taatctcaca
    11881 gggtaaaggc acacttttag aacagttaga gtctgtccaa tcaacaaatt ggcatgagct
    11941 tgcacaagaa gatttattag ccacctttga agaacgtcaa caagaaacag atcaagaaat
    12001 taatgagtat gcgacggaac agtcgtctaa ttgggagaaa gtaaaagagg aactaaataa
    12061 agaagaacag cgagtgattg aagaagaagt acaaaaagtc aaagagcggt acgaaaagaa
    12121 acgcgacaat gcttattcct tgtgtgtaga aaagatcaac aattttacta agacgaatca
    12181 agaagcgtta tcgaaagaaa aagaaaactt gttaaaagaa cgtattaaag aacgaaaaga
    12241 agagttctac cgcggtttac gtacagataa gctaaagatt agcaaagaat taaatgaaca
    12301 actgaataag ctatatcaaa caacgactga agttcttatg gaaaaacacg aacagatcca
    12361 gcaagaatta caagtacaaa ttccaaaatg gaaaaaagag tatgaaattc aacaacaaga
    12421 attgaaagaa caagaagaaa aacaacggca aaaagaaaaa gagcgtgaac aattagaaat
    12481 aagaaaacgg gaacaggatc ttgcggaaca aaaaatggcg atagaaaaac aacggttaga
    12541 gcaagaaaag gaaaaagaag cagctgctcg taaggaacgt caagaacaaa tggatacatt
    12601 gcgtcaagca cagttgaatt atctagcaca acctcaacca gtagctgctg ttcaaacgcc
    12661 agtgaacaac caagcaaatt taactccttc accccagcgt tcctttaacg gatggatggt
    12721 gggatgtatt gcaagtttaa gcttgcttct aggtggagga acagtatttg cttttaatca
    12781 tatcaatcaa tcttcacagg ctgattctgt agccacaacg gcgtcaatca aggaagaagc
    12841 ccaggaacaa gcaagaaaag agtatgaaca acaattagaa gaattattga atcgtaccaa
    12901 tcagtcaaca acagagtcaa gcatggaaaa tagcaaagag agtgattcta gtaaggctaa
    12961 agaaggatca agcgattcaa ctgtacaatc aaacacttcc gaaagttcag aatcaaatga
    13021 ggtgaaataa tgcgtgttag agaaacaacg aagcgaaaag acaaacgatt caatttagaa
    13081 aagaataggt atctttctca tttctatcgc tatactccct caggagaaga gctaccagaa
    13141 aaacatgaca aacgcatttc gaaaaagatt ttttatagtg gacttgtata cctcccttta
    13201 gagtatttag taacaagagt accagaagtt ttcaaccgat tggaaattgt taagggaagc
    13261 ttacaaggaa taaatctgtt tcaattacag gaaatgccac aggtctttca ttttgattca
    13321 gctggttttt ggaatccatt tactcctaca actagtttgg gtacacgttt agcaatttcg
    13381 acagtttgtg tggttccagc tgtacttatg ggattgaaaa tggacatgtg gtttcgtcct
    13441 ctagcagatg gacaaaaagg ggataatcga ttaatgacct taaaagaaat ccaacagatt
    13501 tatccgcaaa tacctgaaac aaaaactact tttccaggtt atggaggtat tccaatcaca
    13561 cattacaaaa aatattggta cattcaaaca gatactgtta atacgtgtat tgttggtacc
    13621 tctcgatcag ggaaaggtca gattgaagtg ttagccacca ttgacaattt atctcgtgca
    13681 gaaaaacaaa gttcaatggt cgttaatgat ccaaaaacag aattatatgt tggtagtaaa
    13741 gatgaactag aagctagagg gtatgatgta tatgccttta atatcaccga tccactgcaa
    13801 tcaatgagtg ataatccatt ggcactcatc gtgaaatact ggaaacgagg agacatagat
    13861 actgcaacac agttaaccaa tactttcaca aatacgattt attatgatgc caacgcttca
    13921 gataacaaat actttaacga aaacgcgcag aaagctgtca atgcgcttat ttttgcgttg
    13981 ttagaacaag ctgatcaaac aggagattac tccaaattga caccgaataa tctcgttgag
    14041 cttctttctg agattggcgg ttttaattat tatccagatc cagacaatga attcaaacag
    14101 ttgaatgcct tagatgaatt tatgaatcag ttgccacctg gaaacattgc aaaaaaacaa
    14161 tatggggcaa cgaaaattgg atctgataaa gcgaagggaa atattttatc aacggcaatc
    14221 acgggattga atccatttac tctaacgaaa attgcaaaga tgacttctca atcaacgatt
    14281 gattataaat cggttgggtt tccaaaatac ttagatttga aattacatga aagtctttta
    14341 aatcaacgag tcgtagtaga attttatcat aagggaaaga aatttcatga agaacgtgtc
    14401 aaagtaggct ataaaggatt tagtgaaatc aattttgatt gtcatttagt tgcaggtgat
    14461 caagtttgtt taaaatacga tcatcaagga aaagaatatg tggcttggta tgaattttct
    14521 caaagagtat tgaaagacga agagggtaat atcgtttatc ggaaaaaacg aggagaaacc
    14581 catttgccag aattagaaaa agaagccgtt ctaacattag atgaggaaaa aagtaactta
    14641 ttagtagagt ctattcggat gcactatacc gataaaccaa tggctatttt tatgcttaca
    14701 cctgattatg atccatctaa ccatatcatt gttagtattt ttcttagtca gttatataaa
    14761 gaattatcta cgcaatgtgt taagactaaa ggagataaat gtcaccgcag gattcatttt
    14821 attttagatg aatttgggaa tatgccacca atggataata tggaaggaat catgacggtc
    14881 acagctggcc gaaacatgtt gtgggatctg tttattcaat cttatcagca actttatgcg
    14941 aagtatggag aacaaaacgc agcgattatc aaagaaaatt gtcagacaca tatttatatt
    15001 atgtcgacag atgataatac catcgaagaa ttttctaaaa aagtggggaa taagacggtt
    15061 gaacaagaga acagtaccat caattcatta ggtatgaata ctcatatcaa tcgcaatgtt
    15121 gattcagatc gtatcttaac tcctgaaaga atttctactt ttttagaagg agaaacgatt
    15181 gtactcgctc ctttaaaacg acaagatttg aaaggtcata aaatacggcc gtatcctatt
    15241 tttaatcatg gggaaacgaa tcttccttat gcttatcaat atattgaaga tttcaatcca
    15301 tcgtgggata tcaatgatat agacatacat tgtacacatg cggacttgga tcttaaggct
    15361 ttacaaattg attatgatta tttcctacca gatgaatatg ctagaaatct ctatcatgga
    15421 ctgcatgatc aattagaaga aaaaaacgaa gaaaatatgt tttataaaat cgttcaatct
    15481 cttgagaatg agacggctaa aaaattgtta attcaatttt acgaagaaca agcagcagat
    15541 cgacttcaag aatatgttga aaagttgatc aaaaataaag aaatttctga aatgattggg
    15601 aaacggttgt tattggaatc tgaaaaggtg gtgaaagaat gatcattgga ggaatttttt
    15661 ctggcatagc cgactggtgg tcaggcttat tcggagaagg ggatgcaaac cccaaaaccg
    15721 taacgaaagt cttacaagat tatgggaatt atctgcagta tcaagatgta tttagttgga
    15781 tttggaacac ttttctgtgg ggattgatta aaggattata taatctcaat actttactag
    15841 aaaaaaccat ttatcaaagc tttgatttaa aagacttatt gaacgccgct ggggtaaatg
    15901 cactatttca aagtttgatt agtaaggtat tggctctttt ttgtgtcgtc acattaattt
    15961 atttaggctt gaaatttttt atgagtaaac acccaccaaa agtcaaaaat atcttggtta
    16021 atttatttat ggccatgatc ttgatttttg gtggtagttc tttaatcgat gaagggttaa
    16081 atatcagtaa aagcttttac ggagacgtca ctgcagcaaa taaagcagat aaaacgggat
    16141 cacctgcttt tcaaattatt caaaataatg tgatcgatgt cagtacgtta ctagcaactg
    16201 acccgaataa agtagaatcc ctaccaacag ataaaagaaa tgctttaaca gcgaaaaatt
    16261 ttaaaacagc gaatatcaat gggattatta ctcctgaaca agctaaaggt atggcaggta
    16321 atgataaaag tgggttatca gatatacaaa aggatcggtt aaaggcatta caataccgat
    16381 tggaactaga tgataatggg aaagaaattc ctgttcaaat tagtgacgaa ggcttagcaa
    16441 aatatgtcta tacttcaggg tatcgtcgat acagtagtaa accaggtatt attttagctg
    16501 gtgaatcttc tttggcagta gcctatttat ttatcctatt tacgatcgtt acttgcatta
    16561 ttgagctggt atttaaaaaa ttctatttag tgattgccgc gtcaacggac tttgagacag
    16621 gtcaacggat gaaaagtgcg atagaagata tttctcaatc cttcttgtta ttggcgttta
    16681 cgattttaga attacgaatc tataccttaa tgctttcagg tatcggtgat ttgcatgcgg
    16741 caggaaagat caatggattc ttgtatgtcg ttgctttgat tgtactaacc attgcgctat
    16801 tcaaaggctc tcaatcagtt acgaaaattt tcggcgttga tacaagcctg aaaaacggca
    16861 gtaattctct tcttagcatg tttgccttag gaaatattgc gaaaaatgtg ggtagcggag
    16921 ctaaaaacct tgcaagtgct ggtaagagtg gtttaagcca tttaaatgat attcgtaaaa
    16981 atggatttgg ccatcgaaaa gatgttaccc ctgataacgg ggaagaacaa tcagacgata
    17041 aagctacaac tgtacctaat agtaagaaaa cagtttccga aatgttcggg aaagcgaaaa
    17101 atggtgtttc taaagccgca gaaggtcttg gttacgtcaa tgaacgtggg ttaaaaggaa
    17161 cagctgaaga tcttacagaa aaagccaaag acaccttaga agataaatta gacggcacga
    17221 gagctaaaga attggctgaa gctgtgaaga atccatccga agcactagaa aaacaaaaag
    17281 aaaaagcttc agaagtcaaa gaaggactaa aagatgcgta tggtgaagga caagtcaatg
    17341 cagcagtgaa agctaataca acaaccgaaa aagaaaatca agaaggtata gtgattcctt
    17401 cagtcaaaga tcaccaagaa gcgttgcact ctaatgaaaa ttcgattgaa gagaaaaatt
    17461 ccatagaaga aagaaattca gaagaaggaa aaaatggaca gttaccaaaa actgatccag
    17521 aacaatatcg ctataaacct aacagtgacc ttgaaaatga gaagcgaatt tcagatttat
    17581 caaaagtaaa tcaagaagac aaagcagaaa atgagggaca gttaccaaaa actgatccag
    17641 aacaatatcg gtatagatct gttaactccg aaaatgaaaa acgcatttca gatttaccaa
    17701 aacgaaatca agaagtacaa acggatgagg attccatcgt tctgccaaat gataatggaa
    17761 tcgaagttgg aactgaaaaa tcaacgaaaa ttggtttacc taaggcacaa aatttaccaa
    17821 tgaaagatag tcgtttgaat caattcaagg ataatgatca aagttttgtt catcaatcac
    17881 ctgcaggtac tgttcaaatg aaaccaagtc gtttgcctga aaatggaaat ctgacaactg
    17941 tttcttacaa tttatctgaa agtggtgaga cagggaatgc gtccgttcaa aatgttgtga
    18001 caagagaagc tgcaccaaaa cctattcaaa acgttcatac aggttacaag ccagcaaatg
    18061 tggcatttac tgcaccaaca aaaataaatg tgacaagaga aacaaaaaac aggaacaatg
    18121 cattgaaaga acaactattg agggatatca aacaggatat caaaccataa aaggcctaca
    18181 agttaggcct tttttctatg tatgaaaagg agaaatcatt tatggataaa tatagtaaca
    18241 tgaaaaaccc tccaagattt agtggagaat ggaagttttt cgcttttttc tttttagatc
    18301 tattaacgct tggtggctgc tttttttggg cgaaaatggt caataatctt gtccacttac
    18361 cactcttttt tgcactcttg aattatggct tatggattgc gatagcgtta gtgattgttt
    18421 ggcgacccta taataaccca ggtcaacgac aaatttttgc gattatcgag tctatttttt
    18481 ttgcggacaa gaaccattat catgcgttag atcctaaccg aaattatcat ggtacgtata
    18541 aggaggatga ataaatgcga gtcaaaggac aaaattcagt tgaaaggaaa tccattttgc
    18601 agtttggaaa accagaagag cgctctatct tggacttatt tccatataaa tcctgtacag
    18661 aagagggagt cttaattact agagaagatc attttcaacg ttattatcgt gtagtttcta
    18721 cagacgtgga aggattaaat gaacaagaga aactagaacg aatgaatcag ttgaccaccg
    18781 tcatgcgtac gtatgtgcca acaattaagt tagttagttt gaccacagag acggatctaa
    18841 cggaacaaat cgtgcaaaag cggcaattat tagataaaaa tcgtatggaa cagtccttag
    18901 gaagaaatct acaacgatta aaaaaatatg aaaagaaatt agtcgaagaa atccaggaat
    18961 tgaaacgagc agaacaagaa cgtcctgact taagcttctt tttcgtcatt gaaggaaaga
    19021 caatcaagga tttacaaacc agaaaccgtc agttaatgcg atctagtggc attttagggt
    19081 taaaaccact ctacaaaaaa gaattgatca agattctgta tcgaatgaac aatatgaatg
    19141 atgagtagga atggagaaga gagaatgaaa tatccgttga tatggttaga aaaagatgtt
    19201 ccgaaggaag agaccactag aaaatttcct cacactttaa gcctgggtaa gttgggaaaa
    19261 gggcaatctt ttaaccaagt aaagaatcaa acaagaagag gtgactgtac atgttagaag
    19321 caattaaaac agctttttca ccacaaaatg atcaaaaagt acttgatcca ttaaagcaac
    19381 taggaaatcg ggaaatagaa attgtaaaat ccaaagggta tgatttagat tttttaaaac
    19441 aagtgatgcc acaaggtggg ttaaattttg atgaagaata tgtgacgtat ggtaatggtt
    19501 attcacgatg tgtgacagtt tatcactaca caaaaaatcc tacgcttttt tggttggcca
    19561 atctcatgaa caatcctcat acagtggcca cactcgatgt tagcacagat gaaaagcaaa
    19621 aagtgattga tcaaatcaat cgtgccttag atgaattaaa tgatcgatca gataatgaac
    19681 gaaaagcgac tgaccgaaat aaaagcgcgg aagaatacct ggaactagcg gaatatgcta
    19741 gaaaattgac ttctaatggg gaaatttcta agcaagtcaa agtgagagta catgtttacg
    19801 gaaacacgat tcaagaagta gatgaacgag cgcaggaact gatcgaaaat ctcaaaggga
    19861 tggattatcg tgcggtgact tatctgcata aaaccaaacg agattggcaa tcgatgttta
    19921 ccatgttcga tgaacaagct gaatggttcg gaaatatcaa agggcaatca ctaccatcgt
    19981 taaacattgg cggaggtttc ccgttccacc accaaacgct aaaagatcca ggagggacac
    20041 aatatgggga aaccatgaca ggcggcccat ttgtctggaa tgcgacgtat aaaaatagtg
    20101 tacggttgtc tactaatacc ttgcttctag gaatgatggg agctggtaaa tcgaccgttc
    20161 ttaaaatgat cgcggaagcc catttagctg caggagactt tatttggggc tttgaaaagg
    20221 gaaaagactt tattcctttc ttaaaggaat ataacggtat tatggtgcgt ttagacggat
    20281 ctgacggaat gatcaatcct ttagagatat ttgccacacg gacgtatgat gaagcatcca
    20341 gtttatatga cgatggatca gtcaaagatt tgaagatcaa tgaagcagcg tcctatcaaa
    20401 cacacttaga caaagtggtc tatcaggtac agttagtgag tcctcagcta aaaggaacga
    20461 tgaaagcaga atttaagacc tacttaaatc gtttttatga agagtatgga acagtaccac
    20521 gcggctttac ttcctcaaat tcgcgttcaa atactgatac gcaagtcaca gggaaagatc
    20581 cagaagctta tccgacgttc aaagaatttt tagacttttt aggacaactg gaattaccag
    20641 gtgcttccca agagaaaaag aatcgaaaag aagaaatgga atccatcgta gaatccttat
    20701 gtgagacgta tggcatgatt tttgatggtc atagtacgat tcgacacctt gaccaacaac
    20761 agttggtctt ttttgacatt gactctatta caggcttaga tcgaggggta caacaatgtc
    20821 aaatgtacat ggctatgacg ttgatttgga atcaggcatt gattcaagga agaagacaac
    20881 gacgtttaat taaagaaaaa caaatggaag aacaagactt caaacgcttc ttggcgatga
    20941 ttgatgagtg ccataatggt gcgacctgtt ctgcagtgaa aagctgtggg ttgcaagtag
    21001 tctaaaaact attgtaataa ctcttataac gagaagtcaa atgagtgggt aacgccacaa
    21061 agggcttcca ctgatactcc gacatgcaac aagtagttta tgcagaccaa cgttgtgtga
    21121 agctcggtga agtcggctga aggataccgt aaggtaaaag aaatagtgaa taccacgaaa
    21181 gttctctaga ggtaaagggt gtatccgata agtcgggtgt ccaaaaaaac ttaatatggt
    21241 gagtatgtac aaacgtactg acgaactagc gaatgtactg tccgaaaggc atagctccta
    21301 gaaatgggag agacagtgag caaaaaatca ctcattgtgc taacttgtgg ttgagtaaaa
    21361 gtcgttgtta tgaaagacca tgctgcgtta caggcgtagg agaagttagg gggcaaaagc
    21421 tagcatctaa gttaaggcat gtggatagat ataagggaac aggggaagcc atcaacatgg
    21481 agagtgcata ctcgatgaag tggtagtaag aaatatgtga atgacaaata acttacttta
    21541 gtgatggtga aagtagagtc acgactgatg aaggttctgt aatggaactg gaggaacagg
    21601 ctcgattcgt ctgtaaaagt catgaaaccc gttcaaccat gggattctcg tatgactaaa
    21661 aaggtcacga gccaattgga gcgtgataaa ccatgacaaa agaaacaagt ccaaaagata
    21721 ggaagttgcg gcatgcagaa tattatggca tgacggaaat cttcgataag atatactcca
    21781 aaagtttgaa gggagataat ttcaagaatc taatgcagat tatcatttct gataacaaca
    21841 ttgtcctagc atatcgtaat atcaagagaa atcacggtag tgtgacaaga ggagaagatg
    21901 gagtaacgat taaagatatt gaaaatctca accgtaatga attcgtagaa attgttagga
    21961 agcgattcgc acattataac cctcggaaag taaggcgtgt agaaattcct aaatataatg
    22021 gtaaattaag accgttgggt attccatcaa tatgggatag aatcgcgcag caatgcatct
    22081 tacaagtatt agaaccaata tgtgaagcaa aattcaataa tcacagctat ggtttccgcc
    22141 caaatagatc agcagaacac gcaatagcag attgtatggc ccgaatgaat caaagtcaca
    22201 tggaatatgt ggtagatgta gatatcaaag gtttcttcga cgaagtcaat catactaaac
    22261 tcatgagaca aatctggtct atgggtatac gagacaaaca gcttctctta atcattagga
    22321 aaatgttaag agcacccgta gtacttccaa atgggaagtt gatataccca acaaaaggaa
    22381 caccacaagg cggaatactt agcccattac ttgcgaacat caatctcaac gaatttgact
    22441 ggtggatagc aaatcagtgg gaggaaaaag atgccaaaga gctaaaacat cattttagga
    22501 aaaatggagc ttgggataaa ggtaatatct atcacaagct cagaaagagt acaactctaa
    22561 aagaaatata cctagtgaga tacgcagatg attttaaaat tttctgtaga aattataatg
    22621 aagcgaaaaa agttttctat gcaactaaaa tgtggttaca ggagcgtcta aagttaccaa
    22681 tatctgaaga aaagtcaaaa atcacaaatc tttcaaaaga agaaagtgaa tttttaggct
    22741 ttacgatgaa attagtgacc aaaggtaaca aaaaggttgt taatacgcat ataggtacaa
    22801 aagcacaaag catgattaaa gtgaaactaa aaaaacaaat caaacgaatt caaaaaagtc
    22861 ctaatagcaa agataccttt atctatattg gagtctataa cagtatggtt attgggattc
    22921 ataattactt caaaattgcg actcattgta gtgtagcaat gcgaaaaatt gcaagagaac
    22981 tcagaccaag ttttgaaata cgactacgag aacaaggaat ctcaaaagaa ggacaatacg
    23041 gaaagtacga aggatacaag ccttacctac ggtcaggaca aatacgatat ataagagggt
    23101 ttccaatatt accagtaggg tatattcaac acagacatcc gatgtgtaaa aaaagaaata
    23161 ttaataaata caccgaagaa ggtagggaag ccattcataa gaagcaacaa accgtagaag
    23221 aatggaagat atcgtggttg tgtagcaatc cagtgcttag taagagagca acgattgaat
    23281 ttgcggacaa tcgaatttca aaattcatcg ctcaaaaggg aagatgtgca gtaacaggtg
    23341 aggagcttat cttatctgaa atgcattgtc atcatattat cccttatcat gaaagcaaaa
    23401 gtgatagcta tgaaaaccta gtgattgtta ctgaggaggt tcatcgggta atacacgcta
    23461 cacaaagtga aacgattgag gaacttctaa aatatctaaa attaaatcca aaacaaaaag
    23521 aaaaactcaa tgagttgaga ttaaaagttg gtaacgaaga aatatcttaa taaatatttg
    23581 taggacggga aaacagaatg tcttttatag acgagggaac gccgtatgcg gtgaaagtcg
    23641 cacgtacggt gtggactggg ggaaaagacg gagataatat caaactctta cctatcagta
    23701 tcgattaatc cagattttat tgaaacggta aattatgtca caaactttca acgagaaatg
    23761 cgtaaagtag aagcaatgac tgttttagct acacaatccc cacaagaaat ggtgccagaa
    23821 aatatgtctt ctgataactt ctcgaaactg aagaaagtct ttgaattttc ttctacgaag
    23881 atctttatgc gtatggatga atctatttta cgtcatatag aaggattagt gggtaaatca
    23941 atgacgaact cagaattaga atccattcct caacaaaatc aaggagacgc tgtgatcaat
    24001 tttggctcaa aagaaaccat tcgtgttcat tttagtccga acaaacgtca attaaaattg
    24061 tttgatggag gaaaataatg gaaaaccaaa atgaaagttt aatcaagcag tatgttaagc
    24121 gtcgtgcaaa gcggcgctta tttttgtggt tgtttggtac ttctgcaggt ttgattacta
    24181 ttttgatcac tgtgttcgtg accctatttc taatacttgc ggcgggctcg attgataatt
    24241 cggattcaga ttcaagcagt ggtggcgaag cttttacagg agaatattcg gaaggcttac
    24301 cgatttataa agaaatcaaa ggaagaggcc ctttttctga tgagattgcg caatatgccg
    24361 taggtgcagc agtgaaatat aaattattac caagtgtgat cctttcgcaa tacggttacg
    24421 aatcagcgtt tggtacatcg gcgtccgcaa gaaatgatct caactatttt gggattactt
    24481 ggtttgatgg ttgtctgttt cctaaaggaa ctgcacgagg aattggtggc attgaaggtg
    24541 gctggtacat gaagtttccc aactcaaaag ctgcattttc ctattacggc tttatggtag
    24601 ccacacaatc caattttaat gcttgtgtag gaaataaaag ccctggcgca agcttattga
    24661 tcttaggacg aggcggttat gccgctgcag gaattactga agacagtgcc tattataaaa
    24721 attgtatgtc tattattaat acaaataaat tgatggagta cgatgagttt gcgattaaac
    24781 actggagaga aggcggcgga actggtggta cgattacagg aagctggggc aatccattcc
    24841 caggaagtag cttagataaa aattcgttca gtggaggaca actttttggg aaaaatccag
    24901 gaggagaatt ccgacctaac gggttccatg atggactaga ctttggttca gtcgatcatc
    24961 caggaagtga gattcatgcg gttcatggcg gaaaagtcgt gtacgttggc aatcctggta
    25021 tttcaggttt gggtgcgtgt gtgatcgtga ttaattacga tggcttgaat atggtgtatc
    25081 aagaatttgc aaatagtaca ggaaattctc gagtgaaagt aggcgatcaa gtgaaagttg
    25141 gtcaagtaat tgggatacga gatacagcac acttgcattt aggatttact cgaatggatt
    25201 ggcgtcaagc acaaggacat gcattcattg atgatggtac atggatcgat ccgttaccat
    25261 ttttgaatag cagtaaaaaa tagatcagga gaaaaaatat ggaaaataaa acgttaaaaa
    25321 tcgtcttaac agctgcaatt agcgttagtt taatcggcaa tattgcgttg ttttggcagc
    25381 tgaaagagga acaagcagca aatacctata aaattgaaga agtggctaaa aacgcgtctg
    25441 agaagctcaa aaaaaattcc tctgaggcac aggcgaagat cgacaagtta aatcaaacca
    25501 tcaatgagaa aaaccaagaa atcgatcagc tgaagcaaca agatggcaca aaagcaaaag
    25561 aggaagtaac tgaagcacaa agaaagacgg cagaagagtt cggtcaattg gccattgata
    25621 aatcattaag cagaaatgaa ttaacggaaa aactaaaaga tgtcgcaacc caagaagtga
    25681 tcgacaaatt aagtcctaca gacgatgatc accaacatga tgattacgga agttactcct
    25741 ttacattagg tgacgtgcaa acttacgctc aaacaagcag tgtaaaagag gaacaaaatt
    25801 ttgtcgtatt tgttgattat acaatcggca atccgcaatt caaagatgtc aaaccacaaa
    25861 aaataaaagg tggattaact gtcactgaaa aacaagtaga tggtcaatgg aaagtcatag
    25921 actttagtta tttcactcgt taggaggaag aaaatgagta agaaaaaagg agaaagacaa
    25981 cgtttcaaaa aacgaaaaag ttatcttaga tggctgggaa tctttatgat tctcggcttt
    26041 ttgattcttg ctagtccgat ttatacgaat cagaaggtag atataccaga tgaggtaagc
    26101 acgaacgcct ttttaaacac gaaagagctg acaatggttt caaaagaaaa aggagcgaac
    26161 cagcaattag tttttgaatt tgcgatcgat gatgaagatc aaagcttgtt aaaagaactg
    26221 gctaatctta attatcgcgt agaagtaaag acagctaaag gggattatca agcaatacga
    26281 gccaaagtga ttaaggtgtc tgatgattat tttgcagtga agctaacgca tgtaccagaa
    26341 gaatatatcg ccatgcgttt aaccattatt cctgaaaaaa ttgatccaaa agtggatatg
    26401 caagaaccac aagatctgat ttattacgtg cacgaagata aggttaaaga tcaagtgaaa
    26461 gacgaagatt atgaacaaca cgcgatcaat tacaaagtga aaggatacaa gaaagaacaa
    26521 aaagcagctc aaaaacaaat ggaatctttc caagcaacca ttgatttgaa tgaagaatta
    26581 gtgaagaagc taaaagatca attgccttat caagtcgcag atgatcagga aaatactgaa
    26641 aacaagatta atagctacca gcaagaaatt gaaacatcga aaacgcaact gaaagatcaa
    26701 gaagagatca ttcaaaaact tcaagaaaaa attgatcgta tgacaaaaga aaagatttag
    26761 aaggacaggt ggagtgaaaa aatgaagcga acaaacttgg ctgacaaaga tactttcgct
    26821 gagcagaaag tattgattaa agcctatctc aaagttgtaa aagctaaaga aatatgtcaa
    26881 gaagtgaatt atctaacaca acaatatctg agttgaagaa tggtagaaag agtttagata
    26941 ctttaaaatt cagatcattt gaagctctat atgtagctgc taaaaaatat tttacagctg
    27001 ataacaaata aaaaacagga gtattttatg tgaaaaaagt atataaaaaa tgcttatgaa
    27061 tcagctatat caccttaacc atttgttaat gagatgggag aaaacattaa ccacgattct
    27121 aacgcaaaca tcaagcacat aaaacattta acactcctcc tttctggctg aagatttcaa
    27181 ccaaacagga agacagcgta tcaattatag catacacttt ttcttaaatt catttttcat
    27241 atgacaaaat atttccttct aatcgacaaa gttagaagga ttttttattg tctaaataca
    27301 caaataacct taatttttaa agagcataag gaaacgtgat atcactttct cacgaaaggt
    27361 gttaggtagg ctgtgcctac cacgtttcta agaaagataa atgatatcaa aattttggat
    27421 ttgtgtgtag atttgtgggt aggatgaaag cgaatgtggg cagtaaaata agcgtttgtg
    27481 tgtagcaaaa tcaaaaaatg tgtagggata tgtgtagcta cacatatccc tacacataat
    27541 aaatttggag gaaaatatgg acttattaat tagaaatatt gaagaaaagt atattaataa
    27601 aattgacaaa cgttgtgaag aacttacggt caagactggc aaaaaatgga gtcgaaatca
    27661 atacctaaaa gttttgatcg aaaatgattt tgatcacgct cttctgaatt ataaaaaaga
    27721 ccaatttgat cggttgttag aaaaatttgt ggatattcaa acttataata cgaaaacttt
    27781 agaagaatat attgcaacaa ataatcaatt aattggtttg ttaattgaat aataaaaata
    27841 gtattgtgaa tttataaaag gaggaaatca attttggcaa aagcaacaag aaaacatgta
    27901 tatctttacg atatgcatat cgaagtactt gatgaaataa tttctactca tgaagatata
    27961 tctaattata gtgaagcagt cagacatttg tgtatgatgt atgatccaaa aatcgaagaa
    28021 aaaataaatc caattcaaat taaattgaat gcaatgggaa aagaaatttc tattttaacc
    28081 gaaatggttt cagagtttgc ggatcttcat ttgaaagata caggaatact aattggtaca
    28141 aattcaactg tttatcaaga agcagaagaa cgtgtggaag gaaaaattaa atccaatcaa
    28201 accaaaaaat attcttctaa gttaaagaaa ccagtgaatg aatctgttca taccagagta
    28261 gatccatttg atccaacgaa gattctaaaa agataaaagt agaaggagaa cgtgatgaat
    28321 aaatcgcctg cagttattct tacttgtcaa tttaccttgc ccaataaaaa atctttttca
    28381 acatacattg attatatgac aagagaaaaa gcactggaag aaatggaacg acgtacgccc
    28441 gaagaagaac aggaactgca acgaatcaag aatgctttag aggattttta tattcctgaa
    28501 ggagaaactt tttcggaaag taagacggat aaagaattca gtgaaacgtc gaatgaagct
    28561 caatcgttga tggaacatgg aatcaatttt gacaagttag aggaacaaga ttttaccaaa
    28621 tatctttctt atatgacccg tcactatgcg ttagaacaaa agaaagaact gacgcaaagg
    28681 gaacaaaaag aataccaacg gttgaaccaa gcaatgaaaa aatatcaaac agagccacat
    28741 aaaaaagctt caggaaatct tcctggagtt ttttctatgg cttcagacga agtgaaagga
    28801 agtgatctga aggagatcaa acaaatcttc caaagaggac aacaaaaagg ctcaatcatt
    28861 tatcaagatg ttatctctca cgacaattcg tatcttgaaa aaatgggctt gtacgatccc
    28921 aaaacagata ccttagatga agaaggtttg aaagcagctg gaagaaaaat gatggagaca
    28981 ttattcgaga aagaacaatt gaatgaaaca ggttactgga tggcaacgat tcaccgtaac
    29041 actaagcata tccatattca ttttgcagtt gttgaaaaag aaaatacgcg taaaccgtat
    29101 actgagattg aaaatggtgt gagttatatc gtaccgaagg ggaagagaag acaagcaaca
    29161 ttagacgcaa tgaaaaccaa ttatgtacat gagttagaac gtttctctta tgaaaaggat
    29221 cgaatgatcg gtatggagaa acgaaattta ttgacacgaa aaagtgattt gcgtaacacc
    29281 ttaacaaaag tagtaaaaga accagcacgt tacgatcgac acgccatgaa cttattaaat
    29341 gaagtatata aaaccctacc tgaaaaacgt tcggaatgga attatggaga tgaaaatcga
    29401 accaagcttt caccatttac aaggggaaaa cttgatgagt taaccaaata tgttttaaca
    29461 aaagaacctg gatatcaaga atatatacag atttcaaaag cattgaaaga agaagccaaa
    29521 agcctttatg gggaaagcaa aagagaaaca aagaatgcag aaaaaaacgc cctctttgat
    29581 ttaaaaaagc gcacaggaaa tgcgatttta acagaactga agagacagga tagtcaaata
    29641 aaaccattaa tagaaagtgt caatcagatg caatctattt acaatgaacg atcctttcga
    29701 acactcaaac agttgccaac aaatgaatac aagtatagtt atcaagaatt cgtaaagcgt
    29761 aggaaacaat tccaacaaag agttgtcacg cagcgaagct tgcgtcaatt aaatcgaaca
    29821 attaatgcac atgaagaaaa ataccacgca agtaaagcat atgaagagca acagcgaaga
    29881 atccaaatgg aacaagaaag acaataggag gaagagaaat gaaacaatat ttagatcaat
    29941 ggaaagtcat agaaggatca ctaaaagaag aacgaatcga acaacttcct gattgtttag
    30001 aaaaagagca tttgtttcag ataagcgaaa tgttgagaaa cgaacagttt gatccaaatc
    30061 aatttttagt tgttgagtac ccagctactg gtgtgtattg ttgtaatcat gtgaagggtg
    30121 aaaaatattt tattattcaa gaatacgaag gtaagttagc gccttattat actacttggg
    30181 aaataaatga agagggaatc aataatttcc catgtgaaag cattgaagag tctatttctc
    30241 tcacggaatg ttaaataaat agagacgtaa aagagtcctg aacgtgattg tccaggactc
    30301 tttttcaatg aattgttttc cgccaattca ctgagtggtg cgattcaatt ttattatatc
    30361 aaaagaaagt gagattccaa agtgaaggga ggaagaagaa atgactcaga caacgattgg
    30421 tgttgtggtt gaaaaaagca gggataatct cgtttttgtg acagaaattc aaacaggtag
    30481 agcttttgta gtcacagaca aagctgcaaa agcgtatcaa aatggcaata ttttaacgtt
    30541 aaatctgact acgaagatgt tcgttgatgc agtagaaaat tatccatttg tttagacaaa
    30601 cgatatttta caaggaggaa acggacatgg cagaagaaaa agaaccacta gataatagtc
    30661 ggttgggaaa gtccaaaaga aaattagtac ggttgcaaaa cgaattaaat aatcaatttc
    30721 aaaagctatt tgatcaccaa aaattgacaa atgggcaacc aatgaatgac aaacgaaatg
    30781 gtcgttcatg gtttaaccag caagaaaaaa tagaaaataa aatacaaagt ttgagagaag
    30841 agatcaagca acaagaaaaa caggtagaaa aacttgaaag acaagaagag ctaaaggaaa
    30901 tgggctataa caagtacggc ggactggata tgacgatcga taatattcca agaatcaaag
    30961 aagaaatcga acgctttgaa aaaggtgaat cgactttttc agccgccacg atccgaaaat
    31021 atcaacggaa gttggaaaca ttagaacagc tgaaagaaaa atcagaaaaa ggaaaagaaa
    31081 atatcctccc tgaagtacaa gcgatcattg acagcggacg agtgacgcaa tggaaaaaaa
    31141 atccaaccat ttattttttg aaaggctatc gaaaagttgc tttagaactg aatgaaaacg
    31201 ggggatttga ggaatcaaaa aaataccaag ccacgtcgga agaggaaaaa gcagctgttc
    31261 gtgaattact tgaagaggct gcaccaactg attctctgaa ggagaaagaa aaagatcatt
    31321 tctatcgagt agaattcaac gaaaatgatc cagaaaaagg attgaaaagt tatggtgggg
    31381 agatcgtaac attagaattg atcgatcaac ttaaaacgtt ggataaccaa tacgctgcag
    31441 aagcaggtta ttataaattc tattttgaag aagtgaagaa cggagaagta gtcgatcaga
    31501 tccgaatgga tctaggggat ggcgtcaaca gtaatcaccc catctattta gagttagcaa
    31561 aattgtgcga acaagtacct gagaaggaac aaaaacaatc ggtcaaaaat gaacctgttt
    31621 cgaaagaaca aatgcagtcg aaagaaacaa aaacaaaaca aaagggctat caaaaacgaa
    31681 cggcagaaga gatcaaacaa gaagttaaat ccctttcgca acaggcactg gatgcggtga
    31741 aaaagcatac ccattcttct gaagacgtca aagaactttt gaactttatg tctcgttttc
    31801 cagaacgatc ctttagaaat caattattga ttgaggaaca atttccaggt gcaacggctt
    31861 gtttaggtcg tgccgcgttg aaaaaagaag gaatctatat caaaaaaggg gaacaaggga
    31921 acaagatctt tgtcagaaaa acggtcaaag gattttatga gaaaggacgt ggctttgttc
    31981 gagaaacaga agctacacca gaagataaaa aacgaatcga aagtggtcaa atcgaagtga
    32041 tcaaaaaa
//
LOCUS       DAZKCW010000030        29949 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000030 DAZKCW010000000
VERSION     DAZKCW010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.030"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..328)
                     /locus_tag="ACG84Z_001574"
     CDS             complement(26..328)
                     /locus_tag="ACG84Z_001574"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9162423.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(353..2446)
                     /locus_tag="ACG84Z_001575"
     CDS             complement(353..2446)
                     /locus_tag="ACG84Z_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFP9162424.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2935..3699)
                     /locus_tag="ACG84Z_001576"
     CDS             complement(2935..3699)
                     /locus_tag="ACG84Z_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFP9162425.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="ACG84Z_001577"
     CDS             complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="ACG84Z_001577"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HFP9162426.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4704..5780)
                     /locus_tag="ACG84Z_001578"
     CDS             complement(4704..5780)
                     /locus_tag="ACG84Z_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFP9162427.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5804..6397)
                     /locus_tag="ACG84Z_001579"
     CDS             complement(5804..6397)
                     /locus_tag="ACG84Z_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HFP9162428.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="ACG84Z_001580"
     CDS             complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="ACG84Z_001580"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HFP9162429.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8067..8366)
                     /locus_tag="ACG84Z_001581"
     CDS             complement(8067..8366)
                     /locus_tag="ACG84Z_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HFP9162430.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="ACG84Z_001582"
     CDS             complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="ACG84Z_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HFP9162431.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(10121..11032)
                     /locus_tag="ACG84Z_001583"
     CDS             complement(10121..11032)
                     /locus_tag="ACG84Z_001583"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFP9162432.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11152..12009
                     /locus_tag="ACG84Z_001584"
     CDS             11152..12009
                     /locus_tag="ACG84Z_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFP9162433.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12196..12558)
                     /locus_tag="ACG84Z_001585"
     CDS             complement(12196..12558)
                     /locus_tag="ACG84Z_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFP9162434.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(12747..12929)
                     /locus_tag="ACG84Z_001586"
     CDS             complement(12747..12929)
                     /locus_tag="ACG84Z_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162435.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            12904..14343
                     /locus_tag="ACG84Z_001587"
     CDS             12904..14343
                     /locus_tag="ACG84Z_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162436.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(14350..16902)
                     /locus_tag="ACG84Z_001588"
     CDS             complement(14350..16902)
                     /locus_tag="ACG84Z_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFP9162437.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(17016..18347)
                     /locus_tag="ACG84Z_001589"
     CDS             complement(17016..18347)
                     /locus_tag="ACG84Z_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9162438.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(18313..19791)
                     /locus_tag="ACG84Z_001590"
     CDS             complement(18313..19791)
                     /locus_tag="ACG84Z_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9162439.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="ACG84Z_001591"
     CDS             complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="ACG84Z_001591"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFP9162440.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            22401..23828
                     /locus_tag="ACG84Z_001592"
     CDS             22401..23828
                     /locus_tag="ACG84Z_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162441.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(23920..24285)
                     /locus_tag="ACG84Z_001593"
     CDS             complement(23920..24285)
                     /locus_tag="ACG84Z_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFP9162442.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(24282..24647)
                     /locus_tag="ACG84Z_001594"
     CDS             complement(24282..24647)
                     /locus_tag="ACG84Z_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFP9162443.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(24839..25087)
                     /locus_tag="ACG84Z_001595"
     CDS             complement(24839..25087)
                     /locus_tag="ACG84Z_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162444.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            25086..25214
                     /locus_tag="ACG84Z_001596"
     CDS             25086..25214
                     /locus_tag="ACG84Z_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFP9162445.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            25271..26965
                     /locus_tag="ACG84Z_001597"
     CDS             25271..26965
                     /locus_tag="ACG84Z_001597"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFP9162446.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            27065..27238
                     /locus_tag="ACG84Z_001598"
     CDS             27065..27238
                     /locus_tag="ACG84Z_001598"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162447.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            27616..28749
                     /locus_tag="ACG84Z_001599"
     CDS             27616..28749
                     /locus_tag="ACG84Z_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFP9162448.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            28780..29100
                     /locus_tag="ACG84Z_001600"
     CDS             28780..29100
                     /locus_tag="ACG84Z_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFP9162449.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(29129..29593)
                     /locus_tag="ACG84Z_001601"
     CDS             complement(29129..29593)
                     /locus_tag="ACG84Z_001601"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9162450.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(29726..>29949)
                     /locus_tag="ACG84Z_001602"
     CDS             complement(29726..>29949)
                     /locus_tag="ACG84Z_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9162451.1"
                     /translation="VSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAA
                     VNLVLSILIYLPFVKVATIQERRKEALDA"
BASE COUNT         9033 a         6212 c         5170 g         9534 t
ORIGIN      
        1 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
       61 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
      121 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
      181 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
      241 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
      301 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
      361 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
      421 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
      481 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
      541 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
      601 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
      661 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
      721 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
      781 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
      841 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
      901 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
      961 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
     1021 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
     1081 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
     1141 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
     1201 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
     1261 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
     1321 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
     1381 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
     1441 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
     1501 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
     1561 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
     1621 aatttctttc tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa
     1681 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
     1741 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
     1801 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
     1861 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
     1921 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
     1981 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
     2041 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
     2101 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
     2161 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
     2221 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
     2281 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
     2341 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
     2401 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
     2461 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
     2521 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
     2581 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
     2641 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
     2701 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
     2761 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
     2821 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
     2881 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
     2941 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
     3001 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
     3061 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
     3121 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
     3181 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
     3241 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
     3301 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
     3361 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
     3421 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
     3481 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
     3541 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
     3601 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
     3661 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
     3721 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
     3781 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
     3841 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
     3901 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
     3961 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
     4021 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
     4081 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
     4141 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
     4201 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
     4261 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
     4321 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
     4381 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
     4441 tctcttaact cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa
     4501 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
     4561 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
     4621 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
     4681 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
     4741 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
     4801 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
     4861 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
     4921 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
     4981 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
     5041 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
     5101 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
     5161 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
     5221 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
     5281 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
     5341 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
     5401 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
     5461 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
     5521 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
     5581 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
     5641 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
     5701 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
     5761 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
     5821 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
     5881 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
     5941 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
     6001 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
     6061 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
     6121 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
     6181 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
     6241 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
     6301 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
     6361 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
     6421 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg
     6481 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
     6541 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
     6601 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
     6661 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
     6721 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
     6781 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
     6841 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
     6901 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
     6961 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
     7021 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
     7081 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
     7141 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
     7201 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
     7261 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
     7321 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
     7381 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
     7441 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
     7501 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
     7561 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
     7621 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
     7681 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
     7741 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
     7801 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
     7861 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
     7921 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
     7981 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
     8041 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
     8101 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
     8161 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
     8221 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
     8281 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
     8341 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
     8401 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
     8461 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
     8521 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
     8581 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
     8641 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
     8701 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
     8761 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
     8821 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
     8881 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
     8941 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
     9001 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
     9061 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
     9121 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
     9181 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
     9241 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
     9301 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
     9361 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
     9421 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
     9481 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
     9541 cgacaacttc gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
     9601 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
     9661 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
     9721 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
     9781 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
     9841 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
     9901 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
     9961 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
    10021 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
    10081 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
    10141 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
    10201 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
    10261 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
    10321 ggttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
    10381 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
    10441 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
    10501 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
    10561 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
    10621 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
    10681 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
    10741 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
    10801 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
    10861 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
    10921 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
    10981 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
    11041 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
    11101 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
    11161 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
    11221 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
    11281 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
    11341 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
    11401 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
    11461 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
    11521 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
    11581 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
    11641 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
    11701 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
    11761 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
    11821 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
    11881 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
    11941 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
    12001 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
    12061 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
    12121 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
    12181 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
    12241 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
    12301 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
    12361 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
    12421 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
    12481 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
    12541 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
    12601 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
    12661 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
    12721 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
    12781 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
    12841 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
    12901 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
    12961 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
    13021 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
    13081 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
    13141 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
    13201 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
    13261 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
    13321 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
    13381 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
    13441 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
    13501 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
    13561 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
    13621 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
    13681 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
    13741 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
    13801 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
    13861 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
    13921 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
    13981 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
    14041 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
    14101 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
    14161 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
    14221 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
    14281 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta
    14341 tagtaacggc tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt
    14401 catgatccct ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa
    14461 taactgttgt gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa
    14521 aataaccatc ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg
    14581 caaaagacct tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc
    14641 ttgagctaag acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg
    14701 catagccaat aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa
    14761 atgataacca gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg
    14821 atctggcgac tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca
    14881 taaaatctgt actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat
    14941 caatccttga gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa
    15001 aatccgccgg ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac
    15061 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc
    15121 ggatcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
    15181 atttttctgc aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac
    15241 atcgactatt ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc
    15301 ttctaaaact ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc
    15361 tttgtgatcc cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc
    15421 tttgactgca ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg
    15481 ggttaaagtc tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa
    15541 aacacgctga ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc
    15601 agaagaaaga gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc
    15661 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt
    15721 tgcttctatt tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc
    15781 tgtcggattg ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca
    15841 gtttttcata atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat
    15901 ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
    15961 ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac
    16021 ggatagaatc atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc
    16081 aatcgtagcc gaaagaagga tatgccaatc cataccatat cgaaatgtcg taaaaataac
    16141 taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt
    16201 tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat
    16261 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
    16321 tcctgaaaaa cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg
    16381 acttttttca gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg
    16441 tgcttcgatt aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc
    16501 tccttttacc agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc
    16561 ttcttgtccc atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca
    16621 gtaactaacg agtccattga cgatcactac gaataaaata atacttcctt caatatattc
    16681 actagaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
    16741 atgctttgct atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc
    16801 ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata
    16861 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
    16921 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
    16981 tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt
    17041 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
    17101 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
    17161 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
    17221 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
    17281 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct
    17341 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
    17401 aaactttttt cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
    17461 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa
    17521 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
    17581 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga
    17641 cagttgattg cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg
    17701 atcatttcaa ttccagcaaa actgaataaa accataggaa atgagactac cattccagca
    17761 aagccaaacg gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg
    17821 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
    17881 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
    17941 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
    18001 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
    18061 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
    18121 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa
    18181 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
    18241 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
    18301 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
    18361 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
    18421 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
    18481 tgttccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
    18541 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
    18601 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
    18661 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
    18721 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
    18781 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
    18841 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
    18901 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
    18961 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
    19021 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
    19081 tactccgcga atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat
    19141 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
    19201 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
    19261 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
    19321 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
    19381 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
    19441 cacattatcg ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc
    19501 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
    19561 attcgatacc caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga
    19621 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
    19681 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
    19741 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
    19801 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
    19861 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
    19921 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
    19981 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
    20041 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
    20101 ggatgatttc gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga
    20161 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
    20221 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
    20281 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
    20341 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
    20401 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
    20461 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
    20521 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
    20581 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
    20641 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
    20701 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
    20761 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
    20821 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
    20881 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
    20941 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
    21001 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
    21061 ttcctacgac agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg
    21121 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
    21181 gatctaagcc gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
    21241 ggaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
    21301 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
    21361 aattcaaaag ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag
    21421 ctaaaggaat cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac
    21481 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
    21541 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
    21601 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
    21661 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
    21721 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
    21781 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
    21841 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
    21901 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
    21961 tgtcttgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
    22021 attttttttt tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg
    22081 gatttttctg ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa
    22141 aatagataac ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac
    22201 atatttttat ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg
    22261 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
    22321 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
    22381 tacaaggcgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
    22441 tgtttttatg tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc
    22501 tcctgcatgt ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg
    22561 aagaacagat cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac
    22621 atatacctcg atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt
    22681 gtctgcttta tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca
    22741 tctctgtcag caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg
    22801 ggatcgaaat cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc
    22861 ttaatgtgtc gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg
    22921 aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag
    22981 aaaataaaga aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg
    23041 ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg
    23101 tcgaatcagc atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct
    23161 ttattttgac actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg
    23221 aagactttca acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag
    23281 ttgctacctt tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg
    23341 cgctgattca tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat
    23401 tttatctttt aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca
    23461 gctggtccag ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg
    23521 tgatcgaatt gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca
    23581 caaattcgga tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg
    23641 attttcaagt tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc
    23701 agtcctcaaa ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg
    23761 aaaatattat tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa
    23821 acaaataagg ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat
    23881 ttctgtaaca atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac
    23941 gggtccgatc tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc
    24001 tagttggaaa atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac
    24061 aagaatttcc aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc
    24121 gctgactcgg tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat
    24181 tgatagacaa acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag
    24241 tttttcgaaa tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt
    24301 ctttgttttt ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg
    24361 ataataataa gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg
    24421 atatcagcaa cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt
    24481 gtatctgcat tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa
    24541 agtttgaata gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa
    24601 atagcaatga tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac
    24661 tttcttttaa tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt
    24721 aaaagttgtt ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc
    24781 tccctccatc cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt
    24841 agtccgtcat cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc
    24901 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
    24961 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
    25021 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
    25081 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
    25141 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
    25201 tcgaatcaat ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg
    25261 aggaatcaca atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc
    25321 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
    25381 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg
    25441 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
    25501 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
    25561 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
    25621 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
    25681 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
    25741 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
    25801 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
    25861 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
    25921 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
    25981 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
    26041 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga
    26101 agaagaatac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
    26161 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
    26221 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
    26281 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
    26341 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
    26401 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctattgt
    26461 cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta
    26521 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
    26581 aaaagaaatg ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa
    26641 tattcgtgaa aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat
    26701 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc
    26761 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
    26821 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
    26881 tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
    26941 tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt
    27001 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
    27061 gcagatgcaa gcttttgaac accgtttacc aagaggttat gaaaaagctg ccctgcatca
    27121 agtaataaga gcagccaagc taaaacagct tcttatgttt ttgacttggt tagacttatt
    27181 accgcagatg caagcttttg aacaccgttt accaagaggt tatgaaaaag gcgtttagtt
    27241 tcgagtatga agaaaaattt tgtgaaaatg gttcctcacg tttttgcata aatttgactt
    27301 aataccgaga aactgatccc ttctgtcata acctcttttt atttatgtct gtttcttttt
    27361 gaaaacaact attttttcaa cgtttactct cttgccaatc caacatcatc taacggatac
    27421 aactatttca atgattacca ttacactaaa aaatcggaaa cacacctctc cgaacacaaa
    27481 tacataagac tatagaatgt ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa
    27541 gatctccttt aaaatgaaat tatctgtagt actaataatg cagacaattt tatgaatctg
    27601 aaaggagcat ctccaatgaa agcagtcact tggcaaggaa aacagaaaat ggaaatcaga
    27661 aacgtagatg atccaaaaat attagaacca acagatgcaa tcatccgtat cacagcaaca
    27721 gccatttgcg gctccgatct gcatctttac catcatggtg aagcagtttt ggaaaaaggg
    27781 tatgttgtag gacacgaacc aatgggaatc gttgaagaag tgggatctca agttcaaaca
    27841 ttgaaaaaag ggcaacgtgt ggttatccct tttaatatta gttgtggtca ttgtcatttc
    27901 tgcctgaatc acatggaaag ccaatgtgat gaatcaaatc cagatcagtt atatggcggg
    27961 cttttcggat ttggcaagtt gaacggtaat cattggggtg gtcaagcgga atatctaaga
    28021 gttccttatg cagactctac ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa
    28081 gttttatttc tatcagatat tttgcccaca gcttattgga gcgttgaaaa cgcaggagta
    28141 aaaaaaggcg atacagttgt gattctaggt tctggtccag tcggtctatt cgctcaaaaa
    28201 ttcgctgtta tggctggagc agagcgcgta atcgcagtag atccagtaca gcaccgtcta
    28261 gataaagcgg ctaattacaa tggggttgaa acttatttct tagaagacac ggcacaagct
    28321 ggaacagaat tgtatgaact ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga
    28381 atggacggat tagagcctgt caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc
    28441 acaatctctc cattacagat ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta
    28501 actggtgttt atatgactcc agcttcttct tacccgctgc aagaattttt tatgcgggat
    28561 atcgctgtca agcatggaca ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg
    28621 attgcagaag gactattcga tcctacacaa atcattactc attcgctgcc actatcagaa
    28681 gcagcacaag catatgagat ctttgacaaa aaagaagata aaaatataaa agttgttttg
    28741 aaaccttgaa ttcagtaaaa aatacaggtg attttcttta tgcccaaaat caaacgaaat
    28801 acccatgaga tcgaaatagg aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc
    28861 ttctatttcc aaaatcgtta cacattgatc tcactggctg tcgatttatt aaccgggatt
    28921 ttctatattt ttggaagcct tgcttcctta actaaaatcc ccgatcgata tggcacctat
    28981 ttttatttgg ctggtgctat tttcttgacg attcgtccta ttctcagaat cgtaaggaac
    29041 atttttattt acgacgaaaa aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga
    29101 gaatttttca aatctcatgc ctcttttttc accctatcgt atcactttga tacagacgag
    29161 cggtcgtccc actttcttcc ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa
    29221 acgtggtatg atctgtaatt aagtaaagtt tttcgtaccc aagttgatgc atttcttttc
    29281 tgatttccgc taatatccgc ttggctatcc cctgcttacg cttttccggt tcaacaaaca
    29341 gggcacaaag atttggtgtc agatcagggc ggttatggaa gtcgttttca atgacgcccg
    29401 ctcctccgac gatggtttct ttttcatcta agaccacata ccattgagga atactttcct
    29461 tattagcgat tccagtacga atactttcct catacacaac agcaggaact ccccattttg
    29521 atgaaaacca attcgcgctt tgttttacta attctgggtg ttctcttaat ttgatccagt
    29581 tatatgtaac caatgtttaa acctccgact aaaataaaac gtttacaaaa attatacaag
    29641 tctttatgaa aattagcaat gacaacaata gtgatgtaaa aaaaaaaaac ggaaaacaat
    29701 cacttgttct ccgttttttg attaatcaag catctaaagc ttcttttctt ctttcttgga
    29761 tcgtagctac cttgacgaac ggtagataga tcaaaataga aagaaccaaa ttgacagcgg
    29821 ctagtacacc acctgcaata ctttttgttg ccaatacacc gccaataatt ggtggagtta
    29881 cccatggagg cataacggta gctgctggca ctaaacctgt agaagtcgca aagtaagcaa
    29941 cactaacta
//
LOCUS       DAZKCW010000031        26817 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000031 DAZKCW010000000
VERSION     DAZKCW010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.031"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(2..349)
                     /gene="rbfA"
                     /locus_tag="ACG84Z_001603"
     CDS             complement(2..349)
                     /gene="rbfA"
                     /locus_tag="ACG84Z_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFP9162452.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(376..2682)
                     /gene="infB"
                     /locus_tag="ACG84Z_001604"
     CDS             complement(376..2682)
                     /gene="infB"
                     /locus_tag="ACG84Z_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFP9162453.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(2695..3006)
                     /locus_tag="ACG84Z_001605"
     CDS             complement(2695..3006)
                     /locus_tag="ACG84Z_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFP9162454.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(3003..3296)
                     /locus_tag="ACG84Z_001606"
     CDS             complement(3003..3296)
                     /locus_tag="ACG84Z_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFP9162455.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(3318..4493)
                     /gene="nusA"
                     /locus_tag="ACG84Z_001607"
     CDS             complement(3318..4493)
                     /gene="nusA"
                     /locus_tag="ACG84Z_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFP9162456.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(4517..4990)
                     /gene="rimP"
                     /locus_tag="ACG84Z_001608"
     CDS             complement(4517..4990)
                     /gene="rimP"
                     /locus_tag="ACG84Z_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFP9162457.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(5134..9486)
                     /locus_tag="ACG84Z_001609"
     CDS             complement(5134..9486)
                     /locus_tag="ACG84Z_001609"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFP9162458.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(9698..11407)
                     /locus_tag="ACG84Z_001610"
     CDS             complement(9698..11407)
                     /locus_tag="ACG84Z_001610"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFP9162459.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(11475..12743)
                     /gene="rseP"
                     /locus_tag="ACG84Z_001611"
     CDS             complement(11475..12743)
                     /gene="rseP"
                     /locus_tag="ACG84Z_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFP9162460.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(12904..13704)
                     /locus_tag="ACG84Z_001612"
     CDS             complement(12904..13704)
                     /locus_tag="ACG84Z_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFP9162461.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(13701..14513)
                     /locus_tag="ACG84Z_001613"
     CDS             complement(13701..14513)
                     /locus_tag="ACG84Z_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFP9162462.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(14708..15265)
                     /gene="frr"
                     /locus_tag="ACG84Z_001614"
     CDS             complement(14708..15265)
                     /gene="frr"
                     /locus_tag="ACG84Z_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFP9162463.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(15268..15990)
                     /gene="pyrH"
                     /locus_tag="ACG84Z_001615"
     CDS             complement(15268..15990)
                     /gene="pyrH"
                     /locus_tag="ACG84Z_001615"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFP9162464.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(16126..17007)
                     /gene="tsf"
                     /locus_tag="ACG84Z_001616"
     CDS             complement(16126..17007)
                     /gene="tsf"
                     /locus_tag="ACG84Z_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFP9162465.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(17106..17888)
                     /gene="rpsB"
                     /locus_tag="ACG84Z_001617"
     CDS             complement(17106..17888)
                     /gene="rpsB"
                     /locus_tag="ACG84Z_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFP9162466.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            18247..18726
                     /locus_tag="ACG84Z_001618"
     CDS             18247..18726
                     /locus_tag="ACG84Z_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFP9162467.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            18943..20034
                     /gene="phnW"
                     /locus_tag="ACG84Z_001619"
     CDS             18943..20034
                     /gene="phnW"
                     /locus_tag="ACG84Z_001619"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFP9162468.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            20027..20812
                     /gene="phnX"
                     /locus_tag="ACG84Z_001620"
     CDS             20027..20812
                     /gene="phnX"
                     /locus_tag="ACG84Z_001620"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFP9162469.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(21158..22849)
                     /gene="argS"
                     /locus_tag="ACG84Z_001621"
     CDS             complement(21158..22849)
                     /gene="argS"
                     /locus_tag="ACG84Z_001621"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFP9162470.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(23271..24218)
                     /gene="arcC"
                     /locus_tag="ACG84Z_001622"
     CDS             complement(23271..24218)
                     /gene="arcC"
                     /locus_tag="ACG84Z_001622"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFP9162471.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(24333..25352)
                     /gene="argF"
                     /locus_tag="ACG84Z_001623"
     CDS             complement(24333..25352)
                     /gene="argF"
                     /locus_tag="ACG84Z_001623"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFP9162472.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(25443..26672)
                     /gene="arcA"
                     /locus_tag="ACG84Z_001624"
     CDS             complement(25443..26672)
                     /gene="arcA"
                     /locus_tag="ACG84Z_001624"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFP9162473.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         7144 a         5790 c         4765 g         9118 t
ORIGIN      
        1 attagtcttt gttcaagtcg cgaagcaatt catcgatatg gttcccatag acaactgatt
       61 catcaagttc aaagaacaat tcaggtgtct tataaatact tagattgtgc cctaactctc
      121 gacgaatcaa tcctgatgct ttattcaatc catcttgtgc ttttttctta tctgatgcta
      181 agtcagataa aatgctgtaa tagatcgttg cttgctgtaa gtcccccgta actttcacat
      241 ctgtgatcgt tacgttctcc acacgagggt cacggacctt tttgcgcaaa atatcattga
      301 cttcttttaa gatttcttga ccgactcggc gatcacggta gttagccata atgattggcc
      361 tccttttatc agtttttagt catttttgac ttcttccatg ataaatcctt caattacgtc
      421 atctactttg atgtcattga atttttcaat catcgcacca cattcataac ccattttgac
      481 ttctttcacg tcatctttga atcgtttcag acttgcaagt tggccttcat agattacgat
      541 tccgtcacgg attacacgga caccgctatc tctacgaata tatccttctg ttacataggc
      601 acctgcaatc gtaccaactt tagaaacttt gaaggtttca cgaacgatca tttgaccggt
      661 gattttttct tcaaattcag ggtctagcat ccctttcatc gcagtttcga tttcttcgat
      721 ggctttatag atgatacggt gaagacgaat atcgacttct tcagtatcag cttgcacttt
      781 tgcctgcggt gtaggacgaa cgttgaaacc gatgataata gcgttgctgg ctgctgctaa
      841 ggttacatca ctttcattga ttgctccgac agctgaatgg acgattttta cacggacacc
      901 ttccacatca atcttcttca atgatgcagc cagtgcttct gctgaacctt gtacatctgc
      961 tttgatgatt acgttaactt ctttcaattc gccttctttc aggctttcaa ataagttgtc
     1021 caaagtcaca cggcttgtgg cagcacggtt ttccaataat gcacgttttg cgcgttcttc
     1081 acccgctgca cgtgctgtct tttcgtcttc gaagactacg aaacggtcac ctgcttgagg
     1141 tacatcattc aagccagtga tttctactgg cgttgcaggt cctgcttctt tatcgcgacg
     1201 gccaagatcg tttgtcatta cacggacacg tccgtaagta ttaccgacaa cgattgggtc
     1261 accaacgtga agtgttcctt cttggacaag taaggttgac acaggacctt tacctttatc
     1321 aagacgtgct tcgatcactg ttccgattgc gcgttgtgtt ggatctgctt ttaaatcttc
     1381 tacttctgcg actaacagga tcatttccag caattcttcg atgttttggc cgaatttcgc
     1441 tgagatctca acaaaaatcg tttctccacc ccatgcttca ggaattaatt catactcact
     1501 taattcttgc ataacatgct gaggatttgc acctggttta tcaattttat ttacagcgac
     1561 gatgattgga acgcctgcag ctttggcatg gttgattgct tcaactgttt gtggcatgac
     1621 gccatcatct gcagcaacaa ctaagatcgt gatatctgtg atacttgctc cacgtgcacg
     1681 catacttgta aaggccgcat gtcctggtgt atccaagaaa gtgattggtt taccatcaat
     1741 atcgatctgg taggcaccga tatgctgtgt gattccgccg gcttcgccgc ttgttacacg
     1801 tgaatggcgc aatgtatcca ataaggttgt tttcccgtgg tctacgtgtc ccataatcgt
     1861 tactactggc ggacgtgaga ctaatttatc tggatcgact tcttctgcct cgaagaattt
     1921 atcgatatca gcaatgtcaa cttggacttt ttcttgtggt tccatgccat agtccgtcgc
     1981 taacagttca atcgtatctt tatccagtgc ttggttttga ttgaccatga caccaagcat
     2041 aaataatttt ttaatgattt ctgctggctc acgatgaatt tttttcgcaa tatctgctac
     2101 gttcatacct tcagtatact ctaatacatc tggcaattca cggaatttgc gtggtggtac
     2161 agctggttta gttgattgtt gctgtttgcc ttttttacct tttttattat aacgattacg
     2221 gttattatta ttaaatttgc cgcgattgtt attgtttggt ttgttgttat tgttagtacg
     2281 gttttgattg ccgccttggc tcgttccttg acgattttgg ctgctggtat ttcccgtatt
     2341 attttggttt gttgttggtt tttttccttg attcacttga ccgctccctt gaccgcgatc
     2401 ttgataactg cggttatttt tatttttttg ttgattgttc gttgtttctt ttttacgttg
     2461 atcgttcggc tgttgattgg ctggttttct gcttgcttgt tgtgcagctt gttgtttcgt
     2521 gcttgggttt ttgaacgctt gttgcaattt cttctcatca ctgctagtaa tcgcacccat
     2581 atggtttttc acatcgatgc caagttgttg tgctttttcc acgacgtctt tactagattt
     2641 tttgagttct tttgctaatt catagattct tttgttgccc atgcaatcac cttcctaacc
     2701 ttcaattagc tccttggtct tcttcgcaaa tccggcatcc attattccga ataccttgcg
     2761 aggttttccg atcatctgcg tgatttctgc ttcagaaaat agctcaaagc aaggaacttc
     2821 ataatatgaa ctcttatctt ttatcttttt tcttgtattc tcacttgcat cggttgccac
     2881 aaacaccaat tttgcttttt gtttgcggat ttcagcaatg gtcagttctt cacccgtgat
     2941 tagttttccc gcgcgcatcg ctagaccgat gagattcatg gctttttgcc gattaactgt
     3001 attcattttc caaataactc tttacgtgct ttttggtgag tgacatagtc aagaagttct
     3061 tgataaaact catctgttaa tgttgtttcg agtactcgat cgagaatttt tttatcccaa
     3121 gcttgttgta cttcttccgg ctcaagtgag acatacgctc ctcgtccagg catttttcca
     3181 gttggatcga tcgatacttc cccttctttt gaacgggtga ttcggaccat ctctttttta
     3241 ggtttcattt cacctgaaac cacggatttg cgtaaaggaa ttttcctttg tttcatctct
     3301 ttgcctcctt actaaagtta agcttctggt ttttcttcga ccgtttcatt gttgaatgca
     3361 attgtttcat attcatcgtc tgttaaatct gactgaacga ttgcttcatc atgcagttct
     3421 tctgtttctt tttgttgttc ttgattttca taaaattccg tcatgtcaga ttctgatttg
     3481 atatcgattt tatggttagt caatttagca gctaaacgtg cattttgtcc gcgtttaccg
     3541 attgctagcg ataattggta gtctggaacg acaactgtgc aggcctttgg atttgtctca
     3601 tcgaagatca catccatgac ttgtgcagga ttcaatgcat ttgcgatgaa tacagctgga
     3661 tcttcattcc attcgacgat atccatgttt tcgcctttta attcattgac gattgcttga
     3721 actcgttgtc cctttggccc gacacatgta ccgactgcat cgatatttgg atcatttgag
     3781 cgaactgcca cttttgaacg atcgccagct tcacgggcga tgctgacaat ttcaacgatt
     3841 ccatcataga cttctggtac ttcttgttca aataagcgac gcaataggtc tggatggctg
     3901 cggctaacaa atacttgcgg acctttagac gtattttcta ctcgggaaac ataaactttg
     3961 attcgatcat gtggttgata aaattcattt ggcatttgat cttgtttaga aagaactgcc
     4021 tcaattttac caagattgac ataaatataa cgtttatcct ggcgttcgac gattccttgc
     4081 atgatgtctt tttcataagc actgaattcg ttataaataa tcgttctttc tgcttcacgt
     4141 acacgctgta aaataacttg tttagccgtt tgcgcagcga tccgtccaaa atcttttggt
     4201 gttacttcaa aacggatcgt atcaccgatc tcatatgctg gattgattaa aagtgcatct
     4261 ttcaatgaga cttccaactg tgaatccatc acttcttccg ttacttcttt taccgcatag
     4321 acatggatct ttcctttttt ctgatcaaat tccacttcga cgttttgtgc ttggccatag
     4381 tgacgtttgt atgcagaaac caatgctgct tctaaagcat cgatcacgat ttcttttgag
     4441 atcccttttt cagcttctaa agcgtctaac gcatttaaca tttctttact catttttttc
     4501 tgattcctct ccgtgattaa aattggatag ctaagcgagc ttttgcaata ttttttcggt
     4561 caaaagtcaa ttctttttct cgtgttttta tgcgtatttt caatgtaagc tgttcagcat
     4621 caaatgattg aagaaatcct tcatattgtt tttcgccatc tactggttgg tataaggaga
     4681 catggacata atcaccaagt gccttttcat agtcgctttc ttttttcaat ggccgctctg
     4741 ctcccgggga ggatacctcc aggaaataag cttgaggaat cggatctgga tctgctgcat
     4801 caagtttttc actcagtttc tcactgacaa aggcgcattc ttcgatatcg ataccgcctt
     4861 ctttgtcaat aaatactcgt aagaaccagc tttttccttc ttttacaaat tcgacttcga
     4921 caagttcaaa attttgttca tctaaaatcg gtgtcaccat ttctgtgact gtttcaacga
     4981 cgctactcaa aagtttcgcc tccttaaaaa ttaagtgcgt aattccatta aaaagagtga
     5041 gcgaaaaatc cgctcactca cagttagtat cattacctat aagaactata ccatactctg
     5101 cttaaaatta caagcagaca ggaaaacaga tgcttatagc atatcgaata acgataattg
     5161 attttcatct ggtagatctt tcaatacgcc attgtcgttc atatattcga tcaatgtttt
     5221 tgaaacttta ccgcgggtgg caagatcttc tttggataaa aatggaccgt cttttcttgc
     5281 ttcaacgatt tgtttcgcca cgttggttcc caaacttggg acagctctaa atggtgcgat
     5341 caacgtatca ccttcaataa caaagttaac ggcatccgat ttatacaaat caatcattcc
     5401 aaatttgaat cctcgttcca gcatttcatt ggctaactcc agcactgtca gttgattctt
     5461 ttcttttacg gaagcatcta atcccttgtc cgtgatttct ttcattgctt gtttcacagc
     5521 atcttttcct ttgcacatgg agactagatc aaagtcgtct gcacgtacag aaaagtatgc
     5581 acagtaatac aaaataggga aataaacctt gaaataagcg acacgaagag ccatcaatac
     5641 gtaagctgca gcatgggctt tcggaaacat atatttgatt tttgaacaag aatcgatata
     5701 ccagtcgggc acattatttt ctttcatcgc cgatagatag gtttctcgca attcatcagg
     5761 gatcttgttc cattgtcctt tacgaacagt ttccatgatt ttaaatgcca tcccgctatc
     5821 taatccagca tggatcaaat aaaccataat atcatcacga cagccgatta cttccgccag
     5881 tgtcgcatct cctcgtcgaa tcaattcttc cgcatttcct aaccatacgt ctgtaccatg
     5941 agatagtccg gaaatttgca gtagttctgc aaaagttgta ggatgcgttt cttctaacat
     6001 ccctcgaaca aaacgagtgc cgaattctgg aatacctaat gtccctgttt tggaataaat
     6061 ttgttcctga cttactccaa gtacttcagg accggcaaat atccgcatca cttccgggtc
     6121 atccgtaggg atcgtttgtg ggtcgatccc tgataaatct tgaagcatcc gaataacagt
     6181 tgggtcatca tgccctagaa tatctaattt caatacatta tcgtgaatcg agtggaaatc
     6241 aaaatgagtc gttttccatt ctgaattttg atcgtctgct ggatattgga tcggcgtaaa
     6301 atcatagaca tccatataat cgggaataac gatgatcccc cctggatgct ggccggttgt
     6361 ccgtttgact ccagtagcgc cttttgctaa tctgtcgact tctgcacttc gaaactgcag
     6421 attattgtcc ctttcgtatc cttttacata gccatatgct gttttgtcgg cgactgtacc
     6481 aatcgttccg gcacggtaaa catagtcttc gccaaacaat actttcgtat agttatgggc
     6541 ttctgcttga taatcacctg agaagttcaa atcaatatcg ggcactttgt ctccatggaa
     6601 tcctaaaaat gtctcaaatg gaatatcatg accgtctttg tttaagcgtg caccacattt
     6661 tggacattgt ttttctggca tgtcaaatcc agaaccatac gtaccatctt caaaaaactc
     6721 ggaatattgg cactctggac aataataatg aggggctaat ggattaactt cagtgattcc
     6781 tgtcatcgtc gcaacaaagc tagagccaac agagccacgt gaacctacta gatagccatc
     6841 ttcattactt ttatgcacta gtttttgggc gatcagataa ataaccgaga agccattacc
     6901 attaatagaa ttcaactctt tttctaatcg tttttgaatg atctcaggta acggatctcc
     6961 gtacatttgt tttgcttttg tgtaactcaa ttctgatatt tcatcttctg aacctggaat
     7021 cttcggtgta taaagttcat ctttgactgg aatcacttct tcgcagatat ctgcgatttt
     7081 attcgtattt tctactacga tctctttcgc tgtttcttcc cctaaaaagt gaaatgcagt
     7141 tagcatctca tcggttgttc ggaaatggac atccggcaaa ctatgacgat tcaacggatt
     7201 cgctccgccc atagaattga tcaaaatttt tcggtaaatg gcatcttctt cgttcagata
     7261 atgtacatta cctgttgcaa caacgatttt atccaaactt tttccgattt ctaccaaatt
     7321 ttggataatt tcttccaaat catgttcatt ttttaccaat tcttgctcga tcaaaggcgc
     7381 atagaccgct tttggcataa cttcaatata atcatagaat tttgctcggt ttcttgcctc
     7441 ttctacccct ttttgcatca tggcttcgaa tatttctccc ttatcacaag ctgagccgat
     7501 caatagattt tcacgcatct ttttcaattg ggagcgtggt attcgtggga cgcgttcgaa
     7561 gtattcgaca ttcgacattg aaatcagttt gaacaaatct ttcagtcctg cctgattttt
     7621 tgctaaaatc gttacatgga aaggtcgagc ccttttgtaa gaatctcctt ctccgatatg
     7681 ctcatttagc tgatcatgat aaagcatgtt atgattgtcc attgcctctt tcacaaagat
     7741 ccatgctaag tgaccagttg cttcagcatc atagattgct cggtgatgct gttccaagct
     7801 aacaccaaac tttttagata acacacctaa tccgaaacgt ttgaattgag gatacagata
     7861 tctagctaat tccaacgtat caatgactgg attggccgct tcaggaatac cataccttgc
     7921 gtagctagta ttcaagaacc ccatatcaaa agccgcgttg tgggctacca aaattgtatc
     7981 ttttgaaaat tcaaggaaca tccgcaatac ttcttcttcc gactttgacc ctcgaaccat
     8041 ttcatccgtg ataccagtca gatctaccgt tgttcgtgac aatggatgtc ctggatcgat
     8101 aaattcatca aagctttcga tcacatttcc tttatacatt ttgactgcgg ctagctcgat
     8161 gatcgtgtca tatactgcag acaatcctgt cgtttccacg tcaaatacga cgtatgtggc
     8221 ttcactcaat gcttcatgtg catcattata agcaattggg acaccatcat ctacgacatt
     8281 cgcttccacg ccgtataaga ttttcacacc tgcttttttt ccagcactat gtgcttccgg
     8341 aaaggcttgc gcaccaccat ggtctgtaat ggcgatagct cggtgtcccc attttcctgc
     8401 ttgtgccaca agatcagaga tgctgtttgt tgcatccatc gtactcatat tgctatgaac
     8461 atgaagctct actcgttttt ccccttcagg agcataatct ttgcgaggtg tatgtttgac
     8521 ttctatgata tcttgcgcat tcatgaccaa atcacggaca aacgtatctt cttgaatact
     8581 tcctcgtacc tttaaccagc taccgacact gatcgcatca aatacttgtt catctttttc
     8641 gccgttcgag aattttttga cgataaatga tgaagtataa tctgtgattt tcaaagtcaa
     8701 gatcttgcgt tttgaacgta gttctctgac ttctttgtcg aatacgtacc cctcaagtgt
     8761 gactcttcgt tcttcttcaa cgatactgat cattggtgtc gttggttcat cggctggaat
     8821 atttcgtcct agctggatgg gtccttcaag agctggcgat tgctcttttc tttccttttt
     8881 cttttgttcg tggacaacta gactttcagc tgcttgcttc ataaaggctt ctgcctgttc
     8941 ttgtttgcgt tcttcaaaaa gtttcaatac acgttccgct tgctgctcat ccacttctgg
     9001 ttcgatacga aattttggga atccgtaact gacgaacaac tcttctacta atggcaagta
     9061 ttgttgcttc aaataagaaa tagctcctgt actgtcgatt ggcaagatga ctttacgatc
     9121 ttttatcaca ggtacctgcg ttttcaatac ttgctgtgct agtggtgtat cgcattgctg
     9181 attttccaaa gcttgggccc agtaatcttg caagagctgt tcatcgaatg tctggtcatc
     9241 tgctaagata ttcagtttga cttgtgcaat atctttaaaa gcgatagtca gatgctgagt
     9301 caatgaccga tatagcataa taggcaaaat tttggaaaaa tgtagcgtaa attcccataa
     9361 acgcgattta cgatggacca ctacactatc catttcacca gcagtaagca gtggatgatt
     9421 tttttctgct tcctctagtt ggatttgttc caacagtttt tcaaataaat ctcgtttttc
     9481 tgacaaagat atacgccctt tctgatgaga aacaatgcaa ttgatcgcat cttatcctct
     9541 tctttttcag taccttttag tatactcgtt ttttctgagt tttacattaa aaaattggaa
     9601 ctgcgattca aatcgcagtt ccaattttaa aagcgaatca tcagattgtc aaaaacagct
     9661 gattcagcta tttttatttt ctgtgtttta acgcttatta ttcgccttgg ttcaagagga
     9721 ttggtaaagt attcgccaat tcttctttac gtacttcaac catttcgcca gttttcttga
     9781 ttttcacttc tacgattcca tccactgctt ttttaccgac agtgattctg attggacagc
     9841 caatcaaatc agaatccgcg aatttcactc ctgcgcgttc atttctgtca tcaaccagta
     9901 cttcatagcc agcttttgtc atcgcttctt ctagttcatt cgtcaggctt gtttggtatt
     9961 cgtcttttag attcatttgg acgatatgca gatcaaatgg cgcaattcct tttggccaat
    10021 tgattccttg ttcatctgaa tgttgttcta cgattgctga taataaacga cttacaccga
    10081 taccataaca gcccataatc acaaattttt ctcgtccatt ttcgtctagt acagttgctc
    10141 ccatagattc actgtaacga gtgccgattt tgaatatatg tccgatttcg attcctcgag
    10201 taaaggcaag aacaccgttg ttgtctggtg aaggatctcc ttcttgtaca aaacgaagat
    10261 cttcataaga aagcacagtg aaatcgcgtt ttggattcac atttttatag tggaatcctg
    10321 tttcgttcgc tccagtaatg gcattcgcta aatcttggac ataacggtct gcatatactt
    10381 ttacgtcatc tgaaacaccg actggtccga cagaaccaaa ctcagcacct agatattttt
    10441 gtgcttcttc ttctgttgct tcttctaaaa agtcagcaga taaaaagttt ttcagtttta
    10501 cgtcattgac ttcatggtct ccacgtacca aaacaaggac aggttgttca tccgcaatga
    10561 acaatacaga cttgatgatt ttttgaggtt caacagaaaa gaaatctgct acttcgtcaa
    10621 ttgattttac gttaggtgta gctactttct ccaattcaag ctgtgtttca tgcgattttt
    10681 ttgatacata gtagcttgta gccatctcca agtttgcagc ataatcactt tcagtcgaat
    10741 aacagatcgt atcctccccg atttctgaga tcgccatgaa ttcctttgag tctttcccgc
    10801 ccattgcgcc gccgtctccg atgatcgagc gaaattctaa gccacaacgc ttgaatactt
    10861 cggtataggc tttttcgtaa tctttatatg tctcgtccaa actttcttcc gttgcatgga
    10921 aagaatatgc atctttcatg ataaactctc ttccgcgaag caaaccgaag cgaggtcgtt
    10981 tttcgtcacg atatttaggt tggatttgat aaagatttaa aggtaatttc ttatatgaat
    11041 tgatttcatt acgcatcaaa tcagtaaaag tttcttcgtg agttggtcca aggatcattt
    11101 ttcgatcatt gcggtctttg aaacgataca agtttggtcc atatgtttcg taacgcccgg
    11161 attcttccca aagttctgct ggcaagatgg caggcatcag catttctacc gctccgattt
    11221 tttcaaattc ttcccgcata atgcgtttca gtttttccaa tacacgattt gctaatggca
    11281 gatatgaata aatacccgct gatacttggc ggatatatcc agctcttagc aagatttgat
    11341 ggcttaatac ttctgcatca tttggaactt cgcgtaatgt tggaatcaac atttttgatt
    11401 gtctcattct atatactcct ttatttcctc aaaatagtta tcgtttgtta ttatacccta
    11461 tttgtcaact ttttctagaa aaagaatcgt tgaatatcgt tccatgtaac tagcaccatc
    11521 aacaacatta aaaatccaaa gccagctaat gtcaatattc cttctttttc ttgacttaat
    11581 ggtttcccgc gaatcccttc aaaaatattc aagactaatt tcccgccatc taaggcagga
    11641 atcggaagca gattgacgat tccgagattc attgaaagaa gcgccatcaa actaataaca
    11701 gttgttacac cttgatttgc tgcttctgaa gacaattggt acatcatgac aggtccgcct
    11761 aatttatcta aactgaaacc tgtaaatagt gatcctaagg ctttgaaaat ttccaatgaa
    11821 ccgctgaaag cttgacgcgt ccctccaatg atcttatcca taaaacctgt attcattggg
    11881 gcttttatac caagttggcc aactttttcg ccatttgact ctacagattt cggtgtcacg
    11941 tcgacagatt gcacctgacc ttctcgttcg atcttaaagt ctaatgtttt acctggattt
    12001 ttcgtaatga ctgttgtcag atcattccat gaatggattt cttttccgtc cacactgact
    12061 acctcatcat tttcttttaa gcctgcttct gccgcagctc cattaggcat gatctctcct
    12121 acgcgattag tgttcgtcac ttgaacacca ccttgcataa atgccagaat gatgaataac
    12181 acgattgcca aaataaagtt attcatgggt ccagcaaagt tggtcagcat acgctgccac
    12241 aatttagccg attggaactg tacgtctttt ggcgcaattc tgatttctgt tccgtcgttt
    12301 tcaataatcg tcgcatcgtg atcaacaggg taggttacta cttctgtttc gtctccattc
    12361 acataaccag tgatagtcag ctcatcttct aaatcataac ggctcaattc catcgggata
    12421 gcatttgtca attggatttt cttacttaaa tttatcttct ctacgatgcc gtcagaattt
    12481 agtaaaagag aaagaggcat tcctggtgcc atttctgttt catcatcccc attgcctgcc
    12541 attcgaacat aaccgccaat aggtaatagg cgaagcgtat atgttgtccc gtcttttgct
    12601 tgatgcccat aaattttcgg acccataccg atagcaaatt cgcggacgag gattcctgat
    12661 cgtttcgcaa agaagaaatg accaaactca tgaacaatca ctaatatacc aaaaacgatg
    12721 ataaatgtca gaatcgtttt catagctttt ttctccttta cttgtttttt gtgtttttta
    12781 taaaacaacg ataaaacact ataattttac catagtatac caaagacacc aatagtatca
    12841 atataatgaa aaataaaaac ctgcgtcttt tatgaaattc acaaagaaac gcaggtatac
    12901 ttactaaata atgccaaata aatgcatgat aggaaataca aacagcaaac tgtcgaaacg
    12961 gtctaagatt ccaccatggc ctggtaagat atttcccgag tctttcacat cataatgacg
    13021 tttgattgca gattcgacca aatcaccaaa ttgtccgact gctgaaaaaa taatcgtcat
    13081 cagaagcatg acaaacatac catgattgaa tagttctttt gctgggtata gcaataaata
    13141 aagaaatgcg actacaacag cactaccgat accaccgagc gcaccttcaa tcgttttgtt
    13201 gggcgaaata tcaggactta acttatgctg accataacgt cgaccaacca tatatgctcc
    13261 gatatcagtt gcccaaacaa taaatagacc aaatatcaaa acagccaagc tttctgttcg
    13321 tgcattgaca aaattctgga aacctattcc cacatacaag ctgacaagca caggaaaacc
    13381 tgcttcatca atcgtatacg tatttttaga aataactgat gttcctaaaa gaatcataac
    13441 tataagataa aataacataa atgtacttac attctctgga agaaagaaaa accatctttc
    13501 ttttggcaaa acaagtaaca ctgcaccaac ggcggataaa actccttcaa aacttaagag
    13561 tgtcaatcct ttcatccgga acagctcgta aactcctact accgctaaga ttgctgctgt
    13621 aagctcaacc gctatgcctc cgatccatat aatcggaata aacaagacta gcgccacagc
    13681 tgctgtgatc acacgttgtt tcatgactga tcccctttct catcttctgt tttttttaca
    13741 ccgccgaatc gacggtctcg attttgataa gaggcgattg cttcttcaag atgcgcacca
    13801 tcaaaatcag gccaaagcgc ttttgtaaaa tacagctcac tatatgcgat ctgccataac
    13861 agaaaattac taattcgctc ttctccactt gtacggatca tcagctcagg atcttgtaac
    13921 tctttaggca agaaacctgt cattaaatgc ttagcaatca attcatcatc gatttcttct
    13981 gcgtgtattt ctccttttgc tacttcttcg gcaatttctt ggacagcagt cacgatctct
    14041 gctctacttc cataattcaa agcaaaattc aataccattc cagtattgtt ttttgtttgc
    14101 tcaattgcac gtcttacagc atcttgcgta tgttctggca atacgttttc ataacccatg
    14161 acatgaactt tgacattttc tttaatcaat tctggtacga acgtatcaaa gaagtcgaca
    14221 ggtagttgca tgagaaaact tacttcatct tttggtcgct tccagttttc agtcgaaaag
    14281 gcataaagcg tcaacacttt cactccaagc cttgatgctt tttttgtgac tttctttact
    14341 gtttccatgc cttctttatg gccagcaact cgtggcaaac gacggttttg cgcccaacga
    14401 ccattgccgt ccatgatgat ggcaatgtgc tgaggaattg gtccatcggt attaaattga
    14461 aattcgcttt tttcttgaat atatttgttt ttttgcggaa aaaaacgtaa cattcttttt
    14521 cctcctatac ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt
    14581 cctatgaaat cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt
    14641 aaataaaaga aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat
    14701 gattttatta aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt
    14761 taatgctgtt atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg
    14821 taatatcacc atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac
    14881 gaatcgcgat ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc
    14941 gttcttctgt cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga
    15001 ttccgatatc acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag
    15061 gtgtgatcat taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg
    15121 ttggcgcacc gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg
    15181 cgcggatttg cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg
    15241 cttctgtcat aattgcatct gccattttta tttccccctt acagttgttc cgatattttc
    15301 gcctaagatt gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat
    15361 atcattatcc atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat
    15421 aacttccaga tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc
    15481 agaataaaca ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc
    15541 cgctcgtaat gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa
    15601 gataacgatc cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc
    15661 gatttgacgc atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt
    15721 atcctgtaaa gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc
    15781 acgttccatg cccatttgtg ctccgatttg tccgcgccag atatttccgc cacccacaac
    15841 gattgccatt tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat
    15901 tactggtggt ttgattccaa atcctgcatc cccagctaaa gcttctccac tcaattttaa
    15961 gactacacgc tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat
    16021 tttaccatac ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa
    16081 aagggagcgc acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg
    16141 gctcataact tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa
    16201 acgtacgaat gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc
    16261 aggatcttta acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg
    16321 tccttctacc attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt
    16381 aagaacagtt ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg
    16441 aggattgata gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc
    16501 atctagaaca gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc
    16561 attgtcgtct ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg
    16621 agttgcttcg atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc
    16681 ttccatgtct gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg
    16741 gaacatttcg tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt
    16801 gttacctttc acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc
    16861 agcctttgcc attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac
    16921 ttcaactaat gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt
    16981 taccatttta gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa
    17041 aaaagctgct tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt
    17101 caaaattatt ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat
    17161 gttgctgtgt tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct
    17221 tcgatgaaag catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg
    17281 tttgaaggga ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg
    17341 attgggatat ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg
    17401 atgtacatta catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga
    17461 cgttcacgtt ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca
    17521 tcttcttcca ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag
    17581 tttgtcaatg ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct
    17641 tcttctttga ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct
    17701 tcttcagcaa cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc
    17761 aagtcaatga tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc
    17821 cagcgacgag tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt
    17881 actgccatgt ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg
    17941 ccggcaaact ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca
    18001 taaagcaccc tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt
    18061 tctgctcaac attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat
    18121 ttctctttgt ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat
    18181 attattgggc aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga
    18241 aagaaaatgc gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg
    18301 atccgtacgc aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag
    18361 gcaacgattt ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc
    18421 gtttcccgct tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag
    18481 gatcggctgg ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg
    18541 acgatcgtca ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc
    18601 aaacctccct ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa
    18661 aatgaggagg acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt
    18721 ttttaatcag agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc
    18781 cttattaaat aaacctttac actctttaca aaaatacatc attttttatt caattttttc
    18841 aacaccttga ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc
    18901 ttgctctttg tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact
    18961 cctggaccat tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact
    19021 tgggatcaag aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct
    19081 caagtatcgg aaggaatata cacaacggtc ttaatgcaag gtagcggctc ctttggggta
    19141 gaatcggtat taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc
    19201 gcatatggac aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat
    19261 gaggtatcgg aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat
    19321 ccctctatct ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat
    19381 ttggaagaga ttgctgctgt cacacaagaa aaagatcttt tgtttatagt ggacgcgatg
    19441 tcaagctttg gtgggatacc gattcgtgta gccgaactag ggattgattt tttgatttcc
    19501 agctcaaaca aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg
    19561 gaactagaaa agcgaaaaaa tgtgagtcga agtttgtcac ttgatctata tgaccagtac
    19621 cgcgtgatgg aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg
    19681 gcttttcaac aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca
    19741 cgttatctcg ccaataatca tgtactacga caaaaaatga cagagatggg gttccagcct
    19801 ttcattcaag aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga
    19861 tttgatttta atcattttta tcagtattta aagcaaaacg gatttgtgat ctatcccggg
    19921 aaaatcagcg atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat
    19981 attttggaac tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt
    20041 aatttttgat tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt
    20101 tagaaatgct tttctagaaa aaggaatcca actgactgac aaagaaatcc gcgaaccgat
    20161 gggaaaatta aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca
    20221 atggatagct atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca
    20281 atttgaacat tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt
    20341 ggaaacgatc gaacggttga gaaacgctgg gatcaatatt ggttccacga ctggatttac
    20401 tgctcctatg atgacaatcg tagcagaaac cgcaaaaaaa gaagggtatt caccagactt
    20461 catggcaact tctgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa
    20521 aaacatgcag tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt
    20581 ctcagatatc caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag
    20641 ttcgctaatg gggatttctt atgatgagta ccaaaaatta gagatgggga aaaaagatcg
    20701 tttaaaacag tctgttgctc ttagattcca acaagctggc gctgatattt gtgtaaacaa
    20761 tttaaaagag ttaacagaat acattttgta cgctgacaag aatccagaat gacttttata
    20821 caaaatcaga ggtcgtgaaa aagctgtact gcatcaagta ataagaacag ccaaacaaaa
    20881 atagctcctc atatttttcg tttggttagg cttattaccg cagatgcaag cttttgaaca
    20941 ccgtttattc gaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttattta
    21001 caaacaaaca gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct
    21061 cggtatttgc tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat
    21121 actcggatca gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa
    21181 gtcctagcaa acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc
    21241 gtgcttcttt ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg
    21301 cttgtgctaa tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag
    21361 acaagaccgt ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat
    21421 tcaatgcata gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg
    21481 cacgagcatg tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt
    21541 ccaggttaaa gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc
    21601 caaccccaac ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga
    21661 tttgttcttt agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc
    21721 ctttacgagt tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggcgca
    21781 tatcgtcaga ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat
    21841 agctttgttc attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt
    21901 acaatgcagc agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca
    21961 acgctggatt caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca
    22021 gcaaatgttt ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt
    22081 caccgttcaa cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca
    22141 tcgattcatc acggaaccat tgccataatt gaatagcctc ttcatcgcct tcttccagac
    22201 gtttgaacca agcacgagct tcttcattta attctggttc tgtttcagct acttcatgga
    22261 attggacata taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac
    22321 cccatttttt gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt
    22381 tgatgcggat tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa
    22441 ctgtcgaacg caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga
    22501 ttggtactgt tccttgattc ccgatattgc tatccccata atgttctttt tctttcacta
    22561 ctgtttgcaa aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc
    22621 cgacaacttc gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga
    22681 tttgctgtgg cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc
    22741 cgtgttcagc tgattttgga ttttctagta attgttcgac ttgttccagt gttaaatcat
    22801 ctttgacagc gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc
    22861 ctaaagtgct cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg
    22921 ccatcactag agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc
    22981 tccatctgat atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt
    23041 tgtatcttct tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt
    23101 actctcttgt tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa
    23161 aacgaaaggc tagtcgtttc tgataaaaaa acaatccaga tggcctaaag gagaagaaat
    23221 accacctgga tagctataaa tcatttcgta aatacgaaag acttaacaaa ttaatcagct
    23281 acgataatcg ttccttcttc agaagctaaa agattctcga tattttctaa agaagtgatg
    23341 attgccttag cgtttggttt tgcttcaaca aatgcaatag ctgcctctac tttcggaagc
    23401 atgcttcctg gagcaaattg cttttcatca atgtattgtt tcatttctga aacagtaaca
    23461 gtttctaatt tcttttgatc tggtttttgg taattgacat acacattgtc tactcctgtc
    23521 aatacgatca gcaaatccgc atcgatgatt tcggctaatt tttctgaagc aaaatcttta
    23581 tcgattacgg cttctcgtcc ttctaatcca gtagctgttt ctacaacagg aatcccaccg
    23641 ccaccaacag agactgtgat aactccttga tcgaccagcg tttcgatgac acgtgcttct
    23701 ttaatcgaga tgggtttagg ggaagcgact acttttctcc atccacgtcc agcatcttct
    23761 ttgaatgtca cagtggagtc agcattcatt tgttctttgg cttcttcttc cgtgtagaat
    23821 ggaccgactg gtttacttgg atttttgaat gaaggatcat tttcatccac aataacttga
    23881 gtgactaaag aaaccacatc tttatcgatc cctttttcct tcagtacttc gcccatggca
    23941 ttttgtaacc agtaaccgat agatccttct gtcattgcaa cacatgtatc taaaggcatt
    24001 gccggtgttt tctcagaatc agcagcttgc tgctgaatca ataggttacc gacttgcgga
    24061 ccatttccgt gggagatgat caattcatct ccttgttcga taaatttcac taaatacttt
    24121 gctgtttcca ttaacgcttc ttgttgggct tttgcacttg catccgtaga caagattgca
    24181 ttacccccta aagcgacaac tacttttcgt ttggccattt cattcgtcct ttcttcagtt
    24241 ctaccgaatt ttctagataa caaaacgagc cagcgttttg tgattttccc tcaatgctga
    24301 ctcgtttttt cgtgagatga atgtggttat gcttaaacgc gagggataaa caagttacct
    24361 aatgttgctg ccatgatcgc tttgattgag tgcatacgat tttctgcttg gtcaaattga
    24421 cgagcatatt tgctgcggaa gacttcatct gttacttcca tttcagtgat gccaaagcgt
    24481 tctttcattt gttcaccgta aacagtgttt gtatcatgga aagctggcaa gcagtgcaag
    24541 aagatcaaac gatctgtgtt gtgtgttttt tctaccattt ccatattgat ttggtaaggt
    24601 ttcaacaatt tgatacgttc ttcgaattta tcttcttcac ccattgatac ccatacatca
    24661 gaataaagga cgtctgctcc gtctacacct ttatcaacat cgtcggtaat catcaattgt
    24721 gcaccggatt tttcagcaaa gccttctgcc attttgacga tttcttcttc aggttgtaat
    24781 tcttttggtg caacgatacg catattcgct cctaaaattg cacctgtgac taataaagag
    24841 ttagccatat tgtttcgacc atctccgcag taagcaacag tgataccttc tactgttcca
    24901 aagttttctt ggatagttaa aaagtcagcg atcatttgtg ttggatgcca ttcatcagtc
    24961 aagccattcc aaactggaac accagagaat tctgctagtt cctctaccat tttttgactg
    25021 aatccacgga attcgattcc atcaaacata cgacctagta ctttagctgt atcttctgtg
    25081 gattcttttt tacctaattg gatatcattt gcacctagat attcaggatg tgcacctaga
    25141 tcgatcgctg cagtagtaaa tgcagaacga gtacgtgtag atgttttttc aaataaaagc
    25201 gcaatatttt ttccttctag atagtgatgt gggataccac gttttttcaa gtctttcaag
    25261 tgttctgaaa aatcgatcaa atattgtaat tcttcttttg taaagtcttt ttctgctaat
    25321 aagcttcttc cttggaatac tgattctttc atattaaaca ttctccttta gattgttttt
    25381 atttaagatt aaagaggaaa tcccgacggc agctgacagt aagaccgccg tcaggaaaca
    25441 aattacttca agtcttcacg gacaagtggt tggctcatgc agcgtggacc accacggcct
    25501 cgtgacaatt cacttgaatt gatttctaac actttgatgc catagctacg aagcaattcg
    25561 ttcgatacat aatttcggtt ataagtgact acaacacctg gagcgattgc caatgtgttt
    25621 gatccatcat tccattgttc tcgaggtgca acgatctcat ctccattacc agttgggatc
    25681 agtacaagat catctaatcc aagagcagct ttcatcgttt cgtgtaagtt atctgaatga
    25741 gtaatcttga tatcatcacc atctggttcg attgtaaaga catccatctt accgtcttta
    25801 ctttgaattg ctggatggat agtgaattta tcgtgatcta ccattgtaaa tacggtatcc
    25861 aaatgcatca ttgcacggtt gtttggaatt ttgattgcta acactttttc aaatcctgaa
    25921 ttttttgcga ataggtggcg tgctaatttt tctaaagctt tcgcattagt tcgttgagaa
    25981 atcccaacag ctactacttt atcgcttaag atcaattcgt ctccgccttc gatatgatct
    26041 ggattttcac gatccaacca tacttcgatt cctttatttg caaatcttgg atgatgtttc
    26101 aaaatatatt ctgtaaacat cgattcacga cgacgtgctt caaaagtcat cttattgact
    26161 gtcatcccat ttcccattga tgcggaaggg tcgcgtgtaa agtacaagtt tggcattggg
    26221 tccatgtaaa atggatagtc atcgtctgct gacagatcgt atagactgct agaacgtact
    26281 tcaatatctt ttgtacgaac cccagccatg attttatcta ccatttcttg cgtttccatt
    26341 gatagaagga actcatgaag accctctctt acagcattcg atgcaatatg agattcatcc
    26401 aacattttat tcaagaattg ttctttgaca ttgcctgcgt caatcgcttc tgccgctaat
    26461 ttttccaagt aaagagtctc gacgccttca ttttgcaatg tctttgcaaa gttgtcatgt
    26521 tcttcttgag caatcggaag atatggaata tcatcgaaca acagacgatc cataatatct
    26581 ggtgtcaaat tttccacttc ttgtccaggc cttttcagta aaactgtctt taatttccct
    26641 atttcagaga aaacgtgaat aggtttatcc atgttgtgtt gcctccttct ttttgattac
    26701 atgtatagga tatcctcctt ttgtaatcac tttcataatt ttgtctcatt caaaatgaga
    26761 cattcctcac attaatattc gataattaaa taattaaacg tttttctatt tttaagc
//
LOCUS       DAZKCW010000032        26620 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000032 DAZKCW010000000
VERSION     DAZKCW010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.032"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(18..716)
                     /locus_tag="ACG84Z_001625"
                     /pseudo
     CDS             complement(18..716)
                     /locus_tag="ACG84Z_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            795..971
                     /locus_tag="ACG84Z_001626"
                     /pseudo
     CDS             795..971
                     /locus_tag="ACG84Z_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1147..1716)
                     /locus_tag="ACG84Z_001627"
     CDS             complement(1147..1716)
                     /locus_tag="ACG84Z_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFP9162474.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1790..3079)
                     /locus_tag="ACG84Z_001628"
     CDS             complement(1790..3079)
                     /locus_tag="ACG84Z_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162475.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            3406..4281
                     /locus_tag="ACG84Z_001629"
     CDS             3406..4281
                     /locus_tag="ACG84Z_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9162476.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4295..4618
                     /locus_tag="ACG84Z_001630"
     CDS             4295..4618
                     /locus_tag="ACG84Z_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162477.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4615..5367
                     /locus_tag="ACG84Z_001631"
     CDS             4615..5367
                     /locus_tag="ACG84Z_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFP9162478.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5357..7528
                     /locus_tag="ACG84Z_001632"
                     /pseudo
     CDS             5357..7528
                     /locus_tag="ACG84Z_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7640..9811)
                     /gene="copB"
                     /locus_tag="ACG84Z_001633"
     CDS             complement(7640..9811)
                     /gene="copB"
                     /locus_tag="ACG84Z_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFP9162479.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHVGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9831..12017)
                     /locus_tag="ACG84Z_001634"
     CDS             complement(9831..12017)
                     /locus_tag="ACG84Z_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9162480.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(12017..12226)
                     /gene="copZ"
                     /locus_tag="ACG84Z_001635"
     CDS             complement(12017..12226)
                     /gene="copZ"
                     /locus_tag="ACG84Z_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFP9162481.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQFEKICQAINGLGYKAEVI"
     gene            complement(12239..12679)
                     /locus_tag="ACG84Z_001636"
     CDS             complement(12239..12679)
                     /locus_tag="ACG84Z_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFP9162482.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12753..13292)
                     /locus_tag="ACG84Z_001637"
     CDS             complement(12753..13292)
                     /locus_tag="ACG84Z_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFP9162483.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(13907..15373)
                     /locus_tag="ACG84Z_001638"
     CDS             complement(13907..15373)
                     /locus_tag="ACG84Z_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFP9162484.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(15684..17765)
                     /locus_tag="ACG84Z_001639"
     CDS             complement(15684..17765)
                     /locus_tag="ACG84Z_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9162485.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(18290..18649)
                     /locus_tag="ACG84Z_001640"
     CDS             complement(18290..18649)
                     /locus_tag="ACG84Z_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFP9162486.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGISLIVNIIWLIISGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(18679..19020)
                     /locus_tag="ACG84Z_001641"
     CDS             complement(18679..19020)
                     /locus_tag="ACG84Z_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162487.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSFFAQF"
     gene            complement(19017..19691)
                     /locus_tag="ACG84Z_001642"
     CDS             complement(19017..19691)
                     /locus_tag="ACG84Z_001642"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFP9162488.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLIAQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(20621..21919)
                     /gene="asnS"
                     /locus_tag="ACG84Z_001643"
     CDS             complement(20621..21919)
                     /gene="asnS"
                     /locus_tag="ACG84Z_001643"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFP9162489.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(21959..23149)
                     /locus_tag="ACG84Z_001644"
     CDS             complement(21959..23149)
                     /locus_tag="ACG84Z_001644"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFP9162490.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(23170..23697)
                     /locus_tag="ACG84Z_001645"
     CDS             complement(23170..23697)
                     /locus_tag="ACG84Z_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFP9162491.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(23744..26533)
                     /locus_tag="ACG84Z_001646"
     CDS             complement(23744..26533)
                     /locus_tag="ACG84Z_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFP9162492.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
BASE COUNT         7446 a         5661 c         4693 g         8820 t
ORIGIN      
        1 aaagaggggg ggatttttta tcgttgtgga atatttaaat accaacgctt gtcatgaaaa
       61 tcttgtgctc cacccttagt atttccttct ggatcgtttg tcgcacgcat catgacgtat
      121 actttcttat tagggaaatc acgcatattg aaagatacat gatagccaac atttcctaaa
      181 gtattataag cttgatttac gtctggtcta taaatcccat cagctcttac tctagctagt
      241 tcttttccag tattgtagtc cataatgaaa atatactcgt atttataatt agcaatgtgc
      301 catccagcta catgcaagtt tgcgttttcg atttctccga actgatcaat gtgggcgtaa
      361 tttgttccat ctgtcagcgt agaatttgca gcacctgctc gagttggatc aattactggt
      421 ttatcctccg aagtagttgg attatcatcc gtaaaaccat gagccaaatc ataggctagt
      481 ttttctttac ttacacccat ttcagaaaga taaccgtaag gatctgtatg atcgccccaa
      541 atattttgtg ttacccataa atgcgatttg attcctggtt ggttataagg agtgtctaat
      601 gttaatggaa taccatattt cattgctgaa tctcttgcca attcaacgta tactttatag
      661 ttcttttcaa aagtttcttt atcatgtgtg tgttgtaact cgatttgcac aggacttttg
      721 gctcacgagg ttgtcctact ctacatcttg ctgatagata tgctgaaagg aaaacaccaa
      781 cattatgttt tgctttttca gctagaacga gacaagcagg aataccttta gaagatatca
      841 aagatttttt aggtcataaa gatgtttcca ctacacaagt ctatgcccat atttctcccg
      901 aagtgaaaaa aagatcaatg aatcaactag aaaactatat agaagagcaa ataaaaaagc
      961 actcaaattg agtgcttttt taagctcact atcactaaaa ctatcactaa ttttatttat
     1021 aagcgaacat gtttctatca ctgatttttt aaatctagcg aaaaaccctt atcttaaagg
     1081 cgttcgttca attctttggc aaggtcttca aagcctggct tgcctagaag tgcgaacatg
     1141 gttttcttat agctcatgta gaaaaatttt cttgatgatg attttatcca tcaattgaga
     1201 ttgactgttt tgctctccta tgatttcagc tatgattgtc cgattttgcg gttttcttct
     1261 taactggtag ttgattttcc cagtttccat caactcgcta agcatatcca cgactccgcc
     1321 aaatccggtc tttttcgtaa taaaacctag tgctaccatt cgttcatcta gattttttgc
     1381 tgtaatcgtc acaccagtaa tgagcgagtg ctgtaatgtt tgggccagct cttccatccc
     1441 ttcagcattg gatacgacgg aagctgtttt gttaataggt tcttcgttta tttcttttgg
     1501 ttctttcctc tccactttca ctgtttgacg aaggacatct agttcttgca agagcgtttt
     1561 gtattgttct tgggtcagca tcacgccagc tactttttca cgattaaata tatatacgcc
     1621 agttcccgcg tctcgcgctt gagcaaatac atccatcggc gatcgtttca cttctgtgat
     1681 cgaagatgtg ggaacttcta atttctttaa ttccaatgga tttcctcctt tactaatcgc
     1741 tttttattat agcacagact gacttgtttt gatctttttt ccaaaggttt tatcggtttt
     1801 tgcctaacca gtaattgata tcggtaagaa gtctttcgat accaaatgaa ggatggtaca
     1861 gatacgtttt ttgatcttcg ttatggtcta gtggaaaaaa atgatcggtg atcactagat
     1921 ctgcataccg aggcggctta tttcgagtac atacatgtat agagatccgt tttcgatgtc
     1981 ttagcgtttt gttcagtacc ccagcaagtc ttcttgcttc ttggtgttca tagcgaaaaa
     2041 aaaagacgat tttcacttca ggagggtgga catctaaata ccctcgttcc tggagtgttt
     2101 tcagtaaaag catcccccac tctactgcgg ggtgtgcaag tgcttgttgg atcgctagcc
     2161 gaaattgata tagtttatct ttggaattgg gaaatttttc taatgtttcc tgataataac
     2221 gaacttcttc tatcagccgg tcatggatac caattacgta acgaagccat tcttggtaaa
     2281 gtacttttat cagctttgat ttgctttcgc tctcaaattc gctattcagc caaaacagcg
     2341 aatcaagctt ttcagtcaca atcgtcaatt tccgatagtc ttgtgtctct tctatccgtt
     2401 tccaccgctt ttcagtaatc tggttacagc tcaagcgcaa aattgctaga taattttttt
     2461 cttttattgg caaaatctgc tcctctctaa atagcaattc aggaaacaat tcaaagaata
     2521 gtgttcgact gtctcctaaa atctcgattt ctgccggatc ctttctttgc ttcaataatt
     2581 ggatgaacat ctcagaaaag gactgctctc catcatctgc aaaaaaatgc ggaaaatctt
     2641 tcaaaaagta aaacagcaga tatcttactt ttctttctga accaaagatc tgtgcttttt
     2701 tataagaaaa agaaaggtgg tactcgccaa accactttct caatcgctct tgcgtagaac
     2761 gatcgtactt ctgctcgtaa ggttcattta atagcagatt tttcagtaaa caaaacgggg
     2821 gtgattggat cagaaaaaca aacaagagat aaggttcgct atatccttga tcataaacta
     2881 actgaacggt tttcttatga agaatcagct gaatgggaca gtcgctttcc gccaaacgtt
     2941 tcagatgccg atccactgtt ttaacatcga ttttcagttc ttcagctaaa tcagcttttc
     3001 gccagatcaa atctttcatt agattgatta gtgaaaataa attctgtgca ttttttgata
     3061 atagtttttg ccatctcatc gatcatttct cacctgattt ctaaacatat tgtttgatca
     3121 aaatgagttc actcctaaaa agataaaaaa ctccctttct atttatttaa atacgcaaat
     3181 cttcctcatt attttttatt ttactcaatt taatcgtatt ctcatttcaa aacgaatgta
     3241 ctttaaaaaa acataataag atcactttgc ttgtaggatg tattcccttc cattacaatg
     3301 aaataaatag cgattttatg agaaggtgat gtgaaaatgg aagaaaaaat agaagaatcc
     3361 aaacaaaaaa tcgatcagtt gatataagaa ttagaaaaag cggtcatcgg caaacgttca
     3421 actatccaat tgatgatcgt ggccctatta gcaggtggtc atgtcttatt cgaagatatt
     3481 cccggtgtag gtaaaacgtt actggtcaaa gcactagcaa aagctgtaca gggaaccttc
     3541 agcagagtcc aatgtactcc tgatctgctg cctagtgata ttcttggttt ttccgtatac
     3601 aattcacaat caaaagagtt tgaatttcgt ccgggaccga tctttaccac gatcttgttg
     3661 gcagatgaga tcaatcgtac gactcctcgt actcagtcag cacttttaga agcaatggcc
     3721 gagaatcatg caacgatcga caacaataca taccctctag acaatcattt ttttgtctta
     3781 gctacgcaaa atccaatcga gtacgaagga acatatcctt tgccggaagc acagctcgat
     3841 cgttttttat tccgactaca aatcggttat ccttcttttg atgacgaact tttgctactt
     3901 ttggataaat tcgaaaaagt gttggataac ttaaatgaag tattgaacag ttatgaaata
     3961 gaagaaataa aaacaaatgt ggcgaatgtc tttgtcagtc ccgaagtggc atcttatgcc
     4021 ttgcagttag tgtcagcaac aagaagtcat gctgccatcc agcttggcat cagtccacga
     4081 ggaagccttt cctttattca ggcagcaaaa gcttatgctt taatccatgg gagaaattac
     4141 gtcacgccca aagatttgca ggatttagtt ccttacgtgt tttcccatcg cctgattttt
     4201 tacgatcgtt cattgaagga agacgaaaag aaacaaatca ttcatactct tgttgcacaa
     4261 attcctattc ctgtgaggta gattgaggta gacaatggaa aaaatcaaag attatttcat
     4321 taattttgtg ttatttctgg tatatttcat cattgtgctt tttgctcttg tattcaacaa
     4381 ttctttaggc tggttcttgt tggccttttt tactctttat gtatcatgga gcttgatttc
     4441 attaagcagc tttctaaaga aactttcggt tacttgtaca ttgcagccac tcgtttatcg
     4501 caaaaaaagt atgcaggtta ttttttccat agcaaaaaag agaacttttt ctttacctct
     4561 ccctcgttta caaatcggct tcccagcaat ctttgcagaa aaaaacaaga gattttgatt
     4621 cttacaaata aaccgcaaga agtccaattg ctttggcagc caaaagaaag aggatgccat
     4681 gaaacattaa ctgtcatttt tacagcctat gatagtctag gacttttcag aaaaagtgca
     4741 aaaagagaga tctcttttcc tgtgactgtt ctgcctgctt tttgtaagat tcaagcagaa
     4801 aaattacaga gagttctgga aaaaaaacag cagctgaacg cgtaccaaag aggtcttgat
     4861 tttcgggaac atcgcgctta tcgtccaggt gattctttca accgaatcga ttggaaattg
     4921 tctgctcata ctcaagagtg gttataccgt gaatacgatt atcaagaaga agaatgttct
     4981 cctctttttt gcttttgggg ttcgcccagt ccaaaatttg aacctctgct agacttgtat
     5041 ttttctttat ggcatttgag aaaagaaaag cagccggaac ttctgatatt aggcaaccgc
     5101 gcctttcatg gcaaagaccc cggtcatacc tattttgctt ctttggaagc tggcgatgag
     5161 aaagcttttt tcgcacactt gaaaaaatat gcaaaaaaac aaatcgtcct ctttgttcct
     5221 gagaattctc ctgaagtctc agaagctatt gaaacattgt caaaagatcg aacggcttat
     5281 cttgtttatt tcgtagaaaa acaactcatg gtccaagaaa aagacaagat atgttcattg
     5341 ccaggaggtg aatggattga cgattaaacg ggaaaaatgg ctgcgtggcg tttactcctt
     5401 tgtgatacta agtgtaggtg ctccgatatt tgtagtagct aatcaattgc aaaacagcta
     5461 ccttcttatc ctaactattg gtgtcctatg ccttattgtc tgctgtattc ctaaaaaatg
     5521 ggtacgtttg ctgctttctt tgccagtaat gataggttgt ttgtttttat attttccttc
     5581 gaagacattt tccatattat ggatcttaca gtttttttcg tcagttacag aggaattctt
     5641 ccatctatcc caaggtaaac tttattattt gccagaaaag acagcttttt ttctcataat
     5701 gttgctgatc tatttattta ttacattgac cgtggattac gactattggt acgcaccctt
     5761 tctttctttg atggcttact tcatgatgct taccgttttt cggaaaaaag atttactgta
     5821 cgaaatgatt gcggtagtaa ctgttttgtt cgtgtatctg gcagcaaggc aatttttctc
     5881 catccggttg ttgtcgggaa acactcgatt ccagtcattg actacagttc tgcttatttg
     5941 tttcttaact tttagcgcta tcttgccttt atatcttccg aaagtacacc aatctctcga
     6001 ggaaacgagt gaaccgatcc gagaatatct taatgatgaa gggctttatg acacactcca
     6061 tgagtatcaa ttaaccggaa gtgcaagaac aggcttcagt gagaatgatg aacagcttgg
     6121 tggaccttta tatgataatg gcgaagttgt ttttacagcg aaccaaaaag gaaatggcta
     6181 ttggaagatc gaaaataaaa atcattacac cggttctgga tggatagaag atcaggacgc
     6241 acccatccaa ccaatccaag aattccctgt tgacatcacg agctaccaaa ccgttataga
     6301 agacaaagaa aacattacat tgaccctaaa aaaacaagct ttcttacctt atccttatgg
     6361 aaatactacc ttgactgatt tttcattagc tagtggacaa acgctttact atttgcctga
     6421 aagccagcga ttcattcctg tcccgaatga atcgacacgt tctgcaactt tacaaacaga
     6481 aaggttagtt tttacgagag aagaattaaa aagcagtcag ttaaaagctg atgatttaga
     6541 aaatcagcag acaaatcttc aattgccaaa aagtttgcct aaacgtattg aggacttggc
     6601 ggtcgaattg accaaaaatg aagcaacttt aattcgtaaa gtcgaagctg tctaacagta
     6661 tttaaaaaca agcggaaatt tccgctattc caaaacggat accgggcata ctccgaaaga
     6721 acacgattat gtggattatt tcctctttga ttcaaaagtc ggctattgtg acaacttttc
     6781 aacttctatg gtcgtccttc ttcgaacact tggtatccca gctcgctgga caaaaggttt
     6841 tacaaatggg ctcagaacag gcacagataa tcaagggaat gaggaataca gcattctcaa
     6901 tagtcatgct cattcttggc cagaggtata ctttcctgga tttggctggc ttccatttga
     6961 accaacccct tcatttgcca atccaatggg ttcacaacca gttgctgaaa caaccgaaac
     7021 cgtccagcct gctatcgaac aaccaaatga aagcgaaaat atggcagaaa ctatttccag
     7081 tgagagatct gaggtcattc catcagaaga aacaacactc acaccagctt ataaaatcgt
     7141 cttattcagc cttggagtgt gtttatccgt cttgttgttc tttctattgt tattcagaaa
     7201 atctctgcgc tggacaagtt atcttatcta tcttcatttt tttgcttcta ctaatacgat
     7261 tgcatatcaa aaacttctta accctttgga aacattggta ccgcgcaaac ccgcagaatc
     7321 tttgcaggaa tatagcctgc gaatagaaca agaattcaag ctagatctgc gtttcattcg
     7381 attaactact caatatgaag cagaaatata tggacgacaa gcagatccgg taaaattcga
     7441 taaaaaaacc tatttagaaa taacgcgtat aataagaaaa acggtataca aaaaaattct
     7501 gacaaaaggg agccgcttca aaaaataaga taaaatttct ggagaatcta cttctggaat
     7561 gccgagaacc agctgattga gtatcgatta ctcgaaaaaa aggttgtgac acgttttttg
     7621 tcacaacctt ttttcattat tatttgattt tcaatgtcaa agcatttaga gctacaacta
     7681 ccgtacttaa cgacatcaag acagcaccaa ctgctggact taatatgata ccaattggcg
     7741 caagaattcc ggctgctagc ggaattgcaa gaatattgta acctgccccc caccagaggt
     7801 tctggatcat tttctttcgc gtttgcttgg ctagatcaag aaaatgcaaa atatcttttg
     7861 gatcgctgtt tgtcaatacg acatccgcag aatcgattgc gatatctgtc cctgcaccga
     7921 ttgccatccc gattgaagca cgggctaaac ttggcgcatc attgatccca tcacccacca
     7981 tgattacttt tttcccttgg tcaaggtatt tctggacaac agcttcttta tcatctggta
     8041 ataaaccgcc ataatattct tcgatcccta aataatctgc tactgcttgg gcagcgtttt
     8101 tattgtcacc agtaagcatg acaggagtga tttttctttc tttcaatgtt cggataaatt
     8161 cttttgcttc tgtttttact acgtcaccta aagcaacgat tgcagctaga tgattttcta
     8221 aaatcaggaa gctgatggta tttccttgtt cttggtaagg tttcaataat gcttgttcta
     8281 cgtttaatcc gagacgctca acttcttttt cattaactat tttcacttgt tgttttttga
     8341 ctgttgcctc tagcccgact cctgaaagat tttttagatt ttcagcttga taaggcttga
     8401 tttcatgttc tttcaaataa ttcataatgc caacagccaa tggatgattg gcattcgctt
     8461 ccaaggctcc tagatattga aggatttcat ttttattgaa cgcatcatca agtacttcga
     8521 cacccgttac agtaaatttt ccttctgtta gtgttcctgt tttgtccagc atgatcacat
     8581 ctagatcatt ggcttgctcc agtgcattgc ggtttttcaa aagtaatccg tttttagctg
     8641 ctattgatgt ggagcgagca acaactaatg ggatagctaa acctagagca tgaggacagg
     8701 cgatgataaa gactgttacc atacgttcta atgcattagg aagatctgtc aagaacaacc
     8761 aggcgatgaa tgccaggata cccacaatta atgcgacata aaacagccat tttgccactt
     8821 tgtcagataa tgactctagc ttggattttt ctccttgtgc ttttcgcacc atttccataa
     8881 ccttcgctag ataaccattt tcaccagttc cagttacttc gatttcgatc gttccatccc
     8941 cattgataga accgccaatc actttgtcat tggcttgttt tttgattcct cttgattcgc
     9001 cagtcacagc tgattcgtca acaattgttt cacctttcaa gattacacca tctgttggca
     9061 ttttatcacc agaccggacg atcaaacgat caccttcgtt tacttctttc aatgaaactg
     9121 tctcttcttt tccatctttc gtcaagcgtt tcactgattc tggcagtaat tctgctagtt
     9181 tttgtaaagc attgctggca ttcgacacag cattcatttc aatccagtga cctagtagca
     9241 taataacgat caaagtagcc aattcccaga agaaatccat gacgtgtgta tgtggattga
     9301 gcagatttgc gataaacgaa tagacactat aaatatatgc aactgtaatc cccatcgcga
     9361 tcagtgtcat catagcagga cttttttgtt tcaattccat cttagctcca cttaaaaatg
     9421 gctgaccgcc atagataaat agtatagttg ctaagatcaa tacgagccaa tcagaaccag
     9481 gaaacgttac ttgaaatgga aattccattc ccatcattgg tgaaaaaaga atgattggga
     9541 tagctaggat aagcgatagc caaaattttt gtttgaaatt ccccatgtgc atggaatgat
     9601 ccatgccgac gtgttcgtga tccatgtgca tcgaatggtc catttgtttg ctgtttgcta
     9661 tatctccatg gttatgtccc atgtgcatgg aatgatccat ctgactatgg tcatgtttca
     9721 tctccatctg tttttcatga gattctgtac tttctttgtt tactacttct tttttatgct
     9781 catgtttttt ctccatatcg ttcccattca tttttactcc atcccttctc ttactttttc
     9841 atgtgtcgat ttaagctcag ggagttcaac aatacactga cggaactaaa cgccatcgct
     9901 cctcctgcaa tgattggatt caaaaagcct agtgcggcaa aaggaatacc aatcgtatta
     9961 tagacaaaag cccagaaaag attttgtttg atttttctca atgtcaacct agacaactcg
    10021 attgtttgtg caatggatgc caaactgcta ttcatcagcg tcacatcggc tgtttccatc
    10081 gcaatgtccg ttccacttcc cattgccata ccgacatcag ctaatgctaa ggccggtgca
    10141 tcattgattc catcgcctgc cataccgact tttttgccat ctttctgaag tttttctacg
    10201 taggctgctt tatcctctgg aagtacttca gcaaagatat gctttggatc aataccaact
    10261 tgtttaccaa tcgtttcggc tgccagtttg ttgtctcctg tcagcataaa aacatctaat
    10321 cctttattct ggagctgctt gattgcttgt ttggcttcta gtttgatttg atcagccacg
    10381 gcaatccacc cgatcacttg cttttcatca gctaaaaaca tgactgtttt tccctgctgt
    10441 tctaattcta acgcgtgttc ttggtattca tcaaatgata ggttcaattc aattaatcgt
    10501 ttacgtgtac ccgcaaaata gcgtactcca ttaatcgtac cgctgatccc agcacctggg
    10561 tgggctgtaa aatcaatcat atcgtatgtt gctgcttctt gcagttttcc gtattccacg
    10621 attgctttac ctagtggatg ttcagaagct tgttctaaag tataaaaaat agataggact
    10681 tcttttgaac cgactagatc tgtaactttg ggctttcctt ctgtaatcgt tccagtttta
    10741 tccaaaacaa tgctgtctaa gtgagcagct gcttctaatg cttctccgcc tttaattaaa
    10801 attccatttc gtgcaccaac acccgttcct accataatag ctgttggggt cgctaaacct
    10861 aatgcacatg gacacgcaat gactaataca gagacactat ggatcaatgc gagttgccaa
    10921 tcaccagtga tcaaacctgt agctatgagc gtgataaacg cgatgactaa tacgatcgga
    10981 acaaaaatcc ctgagatccg atctgcgatt ttttggattg gggctttgct cccttgagca
    11041 tcttccacca tttgaatgat ttgcgctaat actgtctgct tgccgacttg tgtgacttcc
    11101 atgtgtagca gaccattcgt attgattgtc ccgccaaaaa gcgtgtcatc cggattcttt
    11161 tctacaggaa gattttcacc agtaagcata ctttcatcta tcgcactgct tcctgaaata
    11221 attcgaccat ctgctggaat ctgctcacca ggacggatga ctagttgatc accaacgact
    11281 acttcttcaa tcgctaacgt ttcttctttc ccgtttctta tcacttgggc ggtttttgtt
    11341 tgaagagaca tcaattgttt gattgcatta cctgttttcg tttttgctgt atgttccaaa
    11401 tatttgccga gcaaaatcag cgtgatgatc atactgctgc tttcaaaata aagatcttgg
    11461 gggtgtccac ggaaaaatcc gttgtaaatg ctcaatgcaa aggcagccga tgttccaatt
    11521 gctaccaata catccatatt tggtgctttc gtcttgattg catggtacgc acctttataa
    11581 aaacgagcac cgacataaaa ttggacagga gcagacagca ctaactggac gattggaaaa
    11641 tgaaaaaagt gaacaatcgc cgcatggctt cctaacatca tagcaatcat tgacaacatc
    11701 aacggcaaag tcaaaaccgt actcaatata agatcgaata gcattttttt caaatacgct
    11761 tgcttttctt ctgcaatttt ttgtttgtgg gcttcatcgt acaaaattgc accataaccg
    11821 atgttttcta cgctttggat taatttttca gtggtcgtcc cttcatattt gacacttgct
    11881 ttttcagtgg ccaagttgac tgtggcattg accacaccag gttgtccgtt cagctctttt
    11941 tcgatcctag cagaacaatt tgcacaagtc atacctgtaa tgacgaacgt atccattttg
    12001 gtttctgctg ttgccatcaa atcacctctg ctttataacc caatccattg attgcttgac
    12061 aaatcttttc gaattgaact tttgtttcat caaacttgac cgtaccgttt gcttttttca
    12121 aatttacttt cactttttgc acgccgtcaa gtgcgcttac tgtttcttct actcttgctg
    12181 cacaatgatt gcagctcata ccttcgattg aaaattgttg tttcattttt tcttcctcct
    12241 attgatgttg tttacattca cattgacctg ggatacagtt acattcgatc gtatctactg
    12301 gttgcttttg ttccagttgt ttcaaaatct cattgatatc ttcttgagtc aaagtggctt
    12361 cttctactag atccgcaatc gtctctccaa tcctttttgc acagatatgg gaaaaaagat
    12421 tttccgtcgc actgcgaact gtttccatct ccgagacagc tggatgataa atgaattttt
    12481 ttccttcttg ttctgtccag atcacttctt tttttaccaa acgtcccagc aaagttttga
    12541 tcgttgctgg tttccaatcc atcgaatcag ctaagatctg cgtgatttct tgggctgtcg
    12601 tctgtccaag tgtccaaata acacgcatga tctcccactc tgaatcactg atctttactg
    12661 gcgttttgac tttttccatt tatttcacac ctttcgttta caaatgtaat cattagctta
    12721 tgaatacaga ttacgcttgt aaacaaaaac tgtcaattat ttttgctctc tattttcaat
    12781 ttagttaaaa attcttgttt ctctcgtctt gttttaagga tgatcagttt atttcttgca
    12841 ttagctactt ggatcagctg ctgtattttc ggttcattgt tttcttcaaa atgccagata
    12901 aaagataaaa attctaagta ttccctgttt agtttctctg aaaatgattc aggcatatct
    12961 ggccgagatt ttttgtttat ctttcttttt agagaacgcc aaactactcg gtagatggcg
    13021 agataacgcg gcactttaag ccaaatgatc ttatctgctt ctttaatcct ttcctctaat
    13081 gtagaagtat aatttccttc aacaatccat gacggattag ataccataaa cgattgctgt
    13141 tcttgcaaaa accacttttt tgcctgaata ctgtagtctg ttgtatgcca taaaaggtct
    13201 agcggcagta gcggaaagtc ggtgatttct ttgatcttcc ttgcgagggt cgattttccc
    13261 gacccacttt gtccaatcac gatgatcttc attcttctcc ctcacttctc tttggaattt
    13321 ggttcgatca taccacttat aacgccgcaa aaaaacaagg gactgtgaca aaagtcgtgt
    13381 caaagtccct tgtttcgaat aaatggtgtt caatcagctg accttcagca ttaactcaaa
    13441 aaacggcaaa atatgaggag ctattttttc gtttgttcct ctaatactca ggtcaaatcg
    13501 ctgattttac aacctcttcc ttaaacggtg ttctcctgcc aacacctcgg tcacaaggca
    13561 caatagtcaa caaacatgag aagttgtttt ttgaaattgc tccttgtgac tcggagttaa
    13621 acggcaggct cactacctct ttcttaaacg gtgttcaaaa gcttgcatct gcggtaataa
    13681 gcccagcaaa acgaaaaata tgaggggcta tttttgtttg gctgttctta ttacttgatg
    13741 caggacagct ttttcacaac ctctgattca cggtgttcca gaagtagctt ctgcgaaaaa
    13801 caagccgaaa cttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    13861 aagctgacca cttctgtcac aacctcttgt aacaagtatt tctattttaa ggctgaacca
    13921 ctgtttctgg ttcagtgatt tctttgtttt tgtctcgacg agcaattgct ggcaagatca
    13981 tacctaataa gatcaagaca attggtgtga tgatattcgt gaataattgg aaccaccatg
    14041 ctttaggatc agcagtataa tctacttttg gcaccattcc taggatacat gcaaacgcag
    14101 tgaaggcaaa gcaccaagca ccaaagataa aaccgatttt tggattttta acaaatttat
    14161 attcagaatt gaatttctta taagctttat tcaacatcat atatgccaag aacacccata
    14221 ggtaacgcat tggcatgaca actgagttca agttcgtcaa ccattttact aattcattca
    14281 tatctttgat accaaagatc ggcaacaaaa taatgattcc tactagtata cctgtcagaa
    14341 gataaccatt caccaatgta cctttacgat tacgtttacg tagccagttt ggtacaaatt
    14401 ctggatccgc atctgctaac aagattttta gtggtgcatc aattgaaaag gctaatgcgg
    14461 agatttgtcc aatcatgttt gtcaatgcgt aaatgatcat caatgagtta ccgataccat
    14521 agtaattacc taaaatttga aaagcactgt atgccccatt tgccatcaag tctttaggaa
    14581 tattatcgct agcaaacagc atacccattg cgactgagcc taatacagca caaatcccta
    14641 ccattgctgc taagaagatc atccctttag gaaattcctt tgcaggattt cttgtagagt
    14701 tgacataagg ggatattttt tccgctcctc caactgcaaa tactagcatc gaaacggttg
    14761 tgaaataact gaaatcaaat gttggaatat atgttttcac ttgattcata tgtggtgtgg
    14821 caaattccat cgttggattg atgaacggtg ccgttacagc taaaagaata aataagatcg
    14881 acatgacgaa catcgctgtt ccggccagtc cgccaatcac tttcaaagta gaaagtcctt
    14941 ttgttgataa atataaaaag gcaagaaata taataagtga aataactgct accatttgta
    15001 ctgacatcgt atttacgata tttccatttc cttggactgc ccaaccgcca gcaatcagga
    15061 ttgcttgagg cttttgtgcc aaataaggaa tatggacgac ccagtaagtc caagcggcat
    15121 agtatgccag tcgtttatta gatgtcgtat tttcgaccca tgaactgacg cctcctttac
    15181 tatccttgaa ggctgaccct aattgtccaa cgatcaatgc gtatggaata aaataaatgg
    15241 ccaaaatcaa tagccaagag gtgacaactg atactccttg ctgagcatag ttattaacta
    15301 cattccccat gccccaaacc atgttaaatg caattaacgc aacagtaaac cagcgtaatt
    15361 gtttgttgtt cattcgttct ctcctttatg ataaaaattt gttatccaga tgtaatcata
    15421 ttcaattttt aacaaactta caagacagtg ttattttatg tgtgtattct tttatttaat
    15481 acacatcgtt ttttcatatt ttttccatca aaaaaataag ttattttctt ttatttcatt
    15541 taccttattg aatttcaagc tattttgaat tttctgcaaa attaaaaaca ttagttattt
    15601 tataatccta tctattttct ttacattttt cattaagaaa aggatataaa aaaaagagga
    15661 cgttcattcg tcctcttcat tgatcaacgt ttatttttta catgcaagct tcgcatggca
    15721 ttcaaaacag ctaatactgt caccccaaca tctgcaaata ctgcatctcc cattgatgca
    15781 aaaccaaaag cacctaaggc aagtaccaaa atttttatcc caatagcaaa gacaatgttc
    15841 tgtttgacga ttttcaatgt tttctttgct aaatggattg cttctgcaat cttcgatggt
    15901 tgatcattca tgatgactac atctgctgct tcaattgcag catcgcttcc caatccaccc
    15961 attgcgattc ctacatctgc tcttgctagc accggtgcat cgttgattcc atctccgaca
    16021 aatgcggtct ttttattgtt tctttgtaag atttcctcta accgctgcac tttatcttct
    16081 ggaagcaatt cgctatatat cttgtccacg cctacttgct tcccgatatg atcagcaatt
    16141 tttttcgaat cgcccgtcaa catgactgtg ttcttcacac cagccttttt taattgaacc
    16201 aatgcgtcta cggcatcttc tttcaaggta tctgcaataa caagataacc actgtaactt
    16261 tgatcgatcg ctagataaag caatgtaccg atttcttgac ttgaaggaaa agagatttca
    16321 aatctttcca tcaatttgtg attacctgct aatacttgtt tgccatcaac ttcagctaag
    16381 atcccttcac ctgcaaattc ttggatatta gctgttggta aaagcggacc tgcgtagcct
    16441 tctaaaacag attgagcaat cggatgtgta gaaaactgtt ctgcactcgc aacatattgc
    16501 atgaatatct ttggatcgat ttttgtatcg atcgtctgga tcgaaaagtc acctttcgtt
    16561 aatgtgccgg ttttatcgaa taccactgtc tcagtttgtg caagcaactc caagtaattt
    16621 gaacctttta ctaatacacc gattttactt gctcctccga taccgccaaa gaaactaagg
    16681 ggtacggaga tcactaatgc acatggacat gagatcacta aaaatgtcaa tgctcgatag
    16741 atccattcag aaaacgccgc tccagaaaca acaagtggag gtaaaacagc taataaaacg
    16801 gccaatccta caacgactgg tgtgtaatag cgcgcgaatt tagtaatgaa attttcagct
    16861 ggtgcttttt tactgctggc attttctact aattctaata atttgctgat agtagaattt
    16921 tcataagatt tttctacttg aactaaaaat ggtttatttt tattgataaa tccacttaat
    16981 actgtttcac caacatatac agatttaggg actgattctc ctgtaagtgc tgacgtatcg
    17041 actaatgatt ctccttcgat gatcgttcca tctaacggta cacgttcacc aggcttcaca
    17101 agtacaaact gaccgatctg cacgtcttca gggttcacgg tcatcaatcc ttccgtcgtc
    17161 tgcacgtgag ctgtttctgg acggatcgcc atcaattcgc gaatcgattt tcttgaatga
    17221 ctgactgcca atccttggaa atactcgccg atttgataaa atagcatcac tgctacggct
    17281 tctggatatt caccgatcaa catagcgcca atcgtagcaa cagacataag aaaattctca
    17341 tcaaagattt ttcctttgac gatattcatc actgccttct tcactacatc atatcctatc
    17401 agcagataaa tcaataaata ccctatcaag cgaattggtt cattaaaatc aaataatagc
    17461 aataaagcga tacctgcaag ggaaaataaa atccggaaca gcgtatttct ctctttttca
    17521 tttccatgtt cagatacttt ttccttatct atttctgtta ctttgacatc tggttctaat
    17581 tccttcacta ctttttttat ttcttgttca atcgtagcca aatgatcttc ctctgcgtca
    17641 atcgttagtt ttccagaagt gaagtttacc gttgcttcct tgactccatt gatcttctga
    17701 actccttttt cgattttcat tgcacagttc gcacaatcta aaccttctaa tctgtaactt
    17761 ttcattttaa tgacctcctc gcctcaacat atgaatatct cttcataact aattataaat
    17821 gaacggttat tcatatgtca aggtatccga aagaaaaaat gaaaaacatc tgcatcggaa
    17881 aatttcttcc atacagatgt tttggcttat tctttctttt tcttttcgat cattgccact
    17941 gctcttatcc aacccgcact tgccttcttg atcttgacag gatagcaact aagtttgaag
    18001 cctgttgctg gcaatttgtc taaattcatt aatttttcga taggacaata tcttttttca
    18061 atccctgcaa aatgtccttc ccagatattc gaagctccac taagctttca aaaatatagc
    18121 aagagttctt taatgaaaat tatttcaact ttccataaac agtaatccca tataaataaa
    18181 agacgtaaaa gtcacatggg agaacttata caggaaaaca catagagtca ggtgaaatac
    18241 atgtatccca cctgactcta tgcgttttct aacctttatt attctctttt tatacaattt
    18301 ctgcaccgaa tggcatcaac gccaatcgag caagtttgaa agattgcttg gcaaaaggta
    18361 tccctatgat cgtgatacat agaaggatgc cgctgacgac atgtgcgaga gcaattggta
    18421 ggcctgaaat gatcagccag atgatattaa cgatcaatga tatgccagac tggtgataaa
    18481 ttacttcttt gccaaaaggc gcaaaagaaa gggaggcgat cttaaaacat tgcataccga
    18541 ttgggatacc tatgatcgtg atacaccaaa gtatccccgc tgctaaccag ctaagaccac
    18601 cgattagtcc gccgaatata aaccagatga catttcctaa acaactcatt atatttctcc
    18661 ttctattact gtttttgatt aaaactgggc aaaaaatgat tttattcttc tttttttagc
    18721 ttccagcatc aaatattctg caaatttttt ttggatttct tccgtatttt cttttgttac
    18781 taatgtgtgt tggattagtt ttcctgatgg tcgctgatcc aatcgttctt ctgactgttg
    18841 cacgtccgct tgcgcaaatc cgataatccg tttttctttt gttacagcaa cgagcaatag
    18901 tttattctta tcatttaggt cagctgccgt ttttgctttt acgaatgatt ctggatgatc
    18961 agtaatcagc tgattgattt gaggtaaatc ttcttttact gcccacctta tttccatcat
    19021 ttttcacttt tctttcgctc atttttatct ccactaaaaa aatcgactgc ggcaattgca
    19081 tctatccagc tttgtgcaat gatctcatgt ccaccaatcg ttgggtggac cccatcttct
    19141 cttgtatatt tcgaaaaacc ataagcaatc cctaaagcat tgaatatacc atctaaagga
    19201 accagcaatg cgccatattc cttagcaagt ttacgaacaa tttggatttt agggtctaag
    19261 tctttacgcc agccatgacg gtcgtcggtt ataggaagta caaacggctc catcaagatg
    19321 atgttgcaga tttccgctgt ttgaagttca tttagtaatt ttcgataaac ggattcaaat
    19381 tgctgagcag atttctcagt tccgaatata gcctgatcgc tagtattatg ccaggtatca
    19441 ttgattccga tcaaaatcga tacatagtca ggttgtaaag ctaaacaatc ttcttgccag
    19501 cgtacttgca gatctgcaat tttgtctcct cctatcccac ggttcatgca ttcaaattcc
    19561 atcgttggat attgggcgat tagttttccg gcaatcaaaa gtggataacc tttacctaga
    19621 tcagttgctt ctgctcggtc tcttcctgcg tctgtaatgc tatcaccgat aaataatata
    19681 cgttttttca tttgtcaaaa actccttttt gaataaaacg atgattttct tccttatatt
    19741 atcccataag ccctatcaag acgaaagaga aaatatatgt ataaaaaatg acatcagcct
    19801 agtcccttca aacaattgaa tgaacgctca tcaagtgtct agttttttat gctatttttt
    19861 tcttaacgtg ccggattccc cttgattcct tcgttgtttg gtccagagag atcgatcata
    19921 cccaagcttc cgtcaatcag accactgatg acgccatcaa aacatatatt tataggctca
    19981 tctaagactt ctagtaaatg tccctttact aatatctctt ctagattgct tgggatagat
    20041 tggtcataac tttatctggt ccgatgattt caagggtgaa ttgaacttac atatggatta
    20101 ttgcatgctg aaaatacgga cctactccat cttcgaatgt tactattagt ttgttttcag
    20161 gtgctagatg atgctttatt tcaacagcag aagcatcatc aaattagatt tccatttgaa
    20221 ttaccttctt tgtaaatgtt tgattgattg cgatttcgtt atagaacctt gtgaatcaaa
    20281 tagcaatttc ttttgctttc ttctcttgtc tgctggaaac ttcctttatc ccgtatttaa
    20341 aaaaaagaac tgcgagagtt cgcagttctt ttttagaata aacggtgctc tccggccaac
    20401 tcctcggtca caagtcacaa tagtcatcaa acatgaaaaa ctgttttttg aaattactcc
    20461 ttgtgactcg gagctgaacg gcaggcgcac aacctcttga tataaacggt gttcaatcag
    20521 ctgaccctcg atattagcta aaaaaacggt aaaatatgag aagctatttt tccgttttgt
    20581 ttctctaata ctcaggtcaa ggcactgatt tcacaacctc ttatggataa attcggttca
    20641 acaaacgtgg gaatggaata gcttcacgca catggtcgat accagcaatc caagtgactg
    20701 ttcgttcaag gcctagacca aaaccagagt gcggaacaga accgtattta cgtagatcaa
    20761 gataccatga atattctttt tcatccaaac cgtgattacg gatttgttct agcaagaaat
    20821 catagtctgt tgcccgttcg cttccgccaa taatttcacc gtaaccttct ggtgcgatca
    20881 tatctgcaca gatcaccacg tcttctcttg ttggatgtgg tttcatgtag aatggcttga
    20941 tggcttttgg atagtttagg ataaagacag gctgttcgaa tgaattcgca atgaacgttt
    21001 catgaggtga accaaagtct tcgccccatt cgatgtcatc aaatccattt ttcttcagta
    21061 attcgattgc atcatcgtaa gtaatacgag ggaatggcaa ttttgtataa gtttttaaga
    21121 cttctttgtc tcgtcctagt acatctaatg cgtattcgca atgatctaaa acattttgta
    21181 ctaagaatgc tacatattgt tcctgtactt ctaaactttc ttcttgatga gtgaaagcca
    21241 tttctggttc gatcatccag aattcgatca aatgacgtcg tgtttttgat ttttcagcac
    21301 ggaaagtcgg accgaatgaa aagacttttc cgaaagccat agcagcagct tccatgtata
    21361 attggccact ttgagataaa taagcttttt gatcaaagta atttgtttcg aatagatccg
    21421 tagtgccttc tggtgcagaa ccagtcaaga tcggcggatc gattttgaca aaatgatgtt
    21481 gattaaagaa ttcatacgtt gcacgaatga tttcatttct gatctgcata atcgcatgtt
    21541 gtcttgaaga acgcagccat aaatgacgat gatccatcaa gaagtctgtt ccgtgttctt
    21601 ttggtgtgat cggataatcg tggctctcgc ttaccacttc cacatttgta attccgattt
    21661 cataaccaaa ttttgaacga ctgtcttcac ggatttctcc agttactaac acggatgttt
    21721 cttggtgtag atttttagct gtttggaaaa cttcttccgg cacttcgctt tttacaacta
    21781 caccttggaa aaaggctgtt ccgtctctta attgtaaaaa tgcgattttt ccgcttgatc
    21841 gcttatttgc gacccaagcg ccgattgtta ctgtttctcc cacatggttt ttcgaatcga
    21901 tgatttgaat ttgttccacg tatgactctc cttttatatt ccttgaattt cttcaggatt
    21961 aattttgact tttactctca ataaattgct tgattctgcg taccgcttct tctaacgtag
    22021 cgcgatcagt agcataactc atgcggacat tttctggtgc cccaaagcct tcgccagtca
    22081 caagcgctac ccctgtttct tctaaaagat cttctaccca ttgtgtgaca ttttcatatt
    22141 tacacatgcg tagcgtttct tttacattag gaaaaagata aaaagctcct tgcggctttt
    22201 caagagaaac acccggcagt tctgccacaa gcggatataa cgtattcagg cgttcttcaa
    22261 aggcgttccg catttcttcc actgtatctt gctcgccttt caatgcttca acagctgcat
    22321 attgactgac tgctgtcgga ttactggttg actgggaagc aacagcgatc attccattga
    22381 tgatctcaga attccccacc gcataaccaa tgcgccagcc tgtcatcgca tatgttttag
    22441 acacgccgtt gatgatgatg gtctgatttt tgattgcttc tgaaatcgtt gcaattggag
    22501 taaactcatt gccattataa actaaacgac cataaatatc atcagcaact atcaaaatat
    22561 cattttttac tgcccattca ccgattgcct gcagttcatt cttgctataa atcattccag
    22621 tcggattcga tggagaattg atgattacgg cttttgtttt ttctgaacgt gcttgttcta
    22681 gctgctcaac agtaactttc cagctattgg attcttcccc tttcacaaag acaggaagtc
    22741 cttctgccag ttttacttgc tcaccgtaac tgacccagta aggcacagga atgatgactt
    22801 catcttgcgg gtcaaggatc gtttggaaaa gggtatacaa agcaaatttc gctccgtctg
    22861 ttacgactgt ttgtgaaggt tcatagacaa gtccatagtt tttcttcaga taatcaacga
    22921 ttgcctgtcg aagctctggg attcctgctg ttggtgtata atagctagct ttcccattgc
    22981 ggattgcttc gattgctgct tcttggatgt tttctggtgt cgcaaaatcc ggttctccca
    23041 cagtcaaact cagcacatct ctgccttttg cttttaatgc cttggccttt gccgcagctg
    23101 ccaaagtgac agacggttct aatcgttttg ttctttttga taactccatc ccattcattc
    23161 ctttaccttt taaattccct tgattgtctt gacttcatct ccagattcaa agccaatcag
    23221 gtaataattc agtttcccat ttgtttcttt tcctactact tcccacacag gctgatcatc
    23281 atacatccct aaagcagctt tttcgatttg gatttcagga tgggccgcag caattgtctg
    23341 ttttgcttcg ttttcagtca gtccctttgt ttgatccaat acttttactt tttcaccaga
    23401 tttaggaatg ataacggcga tttcttttcc tttatcattt gtacctgtca gtgaaaagta
    23461 tgtcttcttt cgagtaaacc aataaaaatg atcggcttcc tcaagatttg catatttctt
    23521 tgcgatttct actgcttctt tcttcgcctg caccgccgga cgactggaac gcaagtaaaa
    23581 aatcgagctg atcacgatga ccgctaataa aaatacgatc aagccaagta acacgcgatt
    23641 aatcgttttt tcctttgtct gttttttctt caagggtcgt cgctccttta tcttcattcc
    23701 ttttcattat agcagatttt aattatgaaa aaagacagct cctctaactt ccttcttcat
    23761 ttttctttaa gaattcatgg atgtcctgat agatttcctc catagctagc tctttgatcg
    23821 gtactttttt cggtaatgca tggatgatcc gtgcaccata ttttgcagtg actagtcttc
    23881 gatccaaaat aagcaatacg ccacgatctg tctccgtcct tatcaagcga cctaatgctt
    23941 ggcgtaactt caaagctgct ttaggtacgg attcctggta aaaaggattg atcccctctg
    24001 attctaaata agcgttccta gctttgacca tcgggcgaag cggattatcg aagggtaaac
    24061 gtgtgactac aacgatctgc aaagcatctc caggcaaatc tacaccttcc caaaagctgt
    24121 cagcgccaaa caatacgctt ttttctgaca aaatgaagcg tttcaaaagc ttctcccggc
    24181 ttccgccaaa cccttgagct agtatttctc gtcctttttc tagcatagac agatgcattt
    24241 tctgatagac cttctgcaaa acatcatgag aagtgaataa cacaagtatt ggccgatctt
    24301 cttgttcgat cagacctgta agtgctgtct ctaaataatc gatatatgct tgattgctga
    24361 cttgatggac ggcaggtgcc tcttttggca catagatcct tgcctgtttc tcataatcat
    24421 aaggagaggc aatcacttta agaggtgctg cttcaatgcc aagccgctta gagagatagt
    24481 gtcgattagg gccgatcttc agcgttcctc caatataaag aatacgatca tatcgaggat
    24541 accaaacagt cgacggcaac atagccgctt gaaaatcatg gagatgaaaa atcatctgct
    24601 gcgctgtgtt cccaggaacg aaccaatgga tcaaatgatc tcgccagtct tccagccatt
    24661 gatccatcag caagtactgc ttgtctaatt gatcaaataa gctatataaa cttgctaaat
    24721 cgatccgcat ctggtttgtc cagctttctt ggataatctc aaaagtcaga cgcatttgtg
    24781 actgtagctg ctggatctcc tgataaaaaa gctgcaggtg atcaatggct gtcccagatt
    24841 ccagtggcag ctgatccaac atctcttttg tcatcatgac ttcttctgga tactgtccgt
    24901 taggttgctt gccgctcact aaactcatta atccttctgc catacaaatc tgtgcttcgc
    24961 atagcgcaga aagttcttct cgataaatcg ataaccagcg taaggcttca tgttctttcg
    25021 gtaaatagct ttgtattcgg tcaaacagct gatttggttc ttctaattgc tggatttgtt
    25081 tatggaaata gttaatactt aatcgtttgt catttacttt ttcagcgatt tccggcaaat
    25141 gatgtacttc atcgatcaac aaaaatggac tagctggaag caatggttct tttcgctgtg
    25201 tttcttgtat taaaaacgca tgattgacaa tcaaaaaatt actttgcctg attttctttt
    25261 gcaagaaacg aacaaagtct tgttcgtaaa atgactgatt tcttgctaaa aatccaatac
    25321 ctctgtgcgc gatatctgca aagaatgaat ggttcaaatt tgttaaatgt aattcatcca
    25381 aatcaccggt cttcgtttgc gtcagccaaa ctaagaccgc catttgatac aaagcatatt
    25441 gtttttgttc tggcggttcc acaagtgtgc ctttaaaacg ctgtaaatca atatagtggc
    25501 gatagctttt gataattaca ggttgtatgg gctgatctag caattgattc agcaatggaa
    25561 tgtctttttc tatgatctgc tgctgcaaaa ctagcgaaac ggtactgatg acagcgggtt
    25621 tttcaggtgt agccaaataa ctcaatggca gcagataacc gattgtttta cccattcctg
    25681 tagctgcttc gatcatcaaa tcttttgatt catcttttgt gaaatggtcg tagaccgcat
    25741 tcatcagtct gttctgttct tttcgataca tcagtgtttt accaaacatt ttttcttttg
    25801 cttgtttttt tcttggatat gtccgctcac cataatggac ggatgtgaat agttccactt
    25861 cttttttctg caaagctagc ccatcgacga tttctaatga gggatcaagt ggctctggtt
    25921 tttctttcat ttcttcaatc acatgataaa tgaaacgact cgtatccata cctgtgtgtc
    25981 tacttaatcg cgcaatctgc tctaacgtga tgattggcaa ttttctcatc cgttcttcga
    26041 tcagcaaaag aagttgacct gtcacttcgg catcactatc tgcctgatga ggattctcat
    26101 gaataaatcc aaggctttct gacaaatcag ctaagcgaaa gcttggttcc gtcggcaaga
    26161 aaatttgtgc aagttctact gtatcgatgc ctggtatctt caaactagga agtccgcatc
    26221 gcatgagttc atggttcaaa aaattataat caaaataaat attatgcgcg acaaatatgg
    26281 tgtctgccaa aagattgtaa atcgtttggg cgacatcttc gaaataaggc gctttttgga
    26341 cgcgttgatt cgtgatccct gttaaatgct ggatttgttt tgaaatcttc cgccctggat
    26401 gaatatcgat cgaaaaacgt gaagtgatcc gacctgattc aatcatgacg cagccaaatt
    26461 ggatgatccg atcttctttt ggattcgtcc cagtcgtttc gatatcaacg actgcataag
    26521 ttcttggttt caaaatatct tcctcttctc ctgcctctaa tgttcttttg aaattatact
    26581 acaaagtgca gaaaaatact ctcatcgctt tttaaagaaa
//
LOCUS       DAZKCW010000033        26453 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000033 DAZKCW010000000
VERSION     DAZKCW010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.033"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(38..634)
                     /locus_tag="ACG84Z_001647"
     CDS             complement(38..634)
                     /locus_tag="ACG84Z_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFP9162493.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            984..1328
                     /locus_tag="ACG84Z_001648"
     CDS             984..1328
                     /locus_tag="ACG84Z_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFP9162494.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            1329..1748
                     /locus_tag="ACG84Z_001649"
     CDS             1329..1748
                     /locus_tag="ACG84Z_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFP9162495.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1840..2190)
                     /locus_tag="ACG84Z_001650"
     CDS             complement(1840..2190)
                     /locus_tag="ACG84Z_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162496.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(2156..3487)
                     /locus_tag="ACG84Z_001651"
     CDS             complement(2156..3487)
                     /locus_tag="ACG84Z_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFP9162497.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3742..4308
                     /locus_tag="ACG84Z_001652"
     CDS             3742..4308
                     /locus_tag="ACG84Z_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9162498.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            4453..4540
                     /locus_tag="ACG84Z_001653"
     tRNA            4453..4540
                     /locus_tag="ACG84Z_001653"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4485..4487,aa:Ser,seq:cga)
     gene            4876..5850
                     /gene="bsh"
                     /locus_tag="ACG84Z_001654"
     CDS             4876..5850
                     /gene="bsh"
                     /locus_tag="ACG84Z_001654"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFP9162499.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            6175..8070
                     /gene="asnB"
                     /locus_tag="ACG84Z_001655"
     CDS             6175..8070
                     /gene="asnB"
                     /locus_tag="ACG84Z_001655"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFP9162500.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(8265..8711)
                     /locus_tag="ACG84Z_001656"
     CDS             complement(8265..8711)
                     /locus_tag="ACG84Z_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFP9162501.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8939..9088
                     /gene="rpmG"
                     /locus_tag="ACG84Z_001657"
     CDS             8939..9088
                     /gene="rpmG"
                     /locus_tag="ACG84Z_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFP9162502.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            9176..9694
                     /locus_tag="ACG84Z_001658"
     CDS             9176..9694
                     /locus_tag="ACG84Z_001658"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFP9162503.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(9771..10727)
                     /locus_tag="ACG84Z_001659"
     CDS             complement(9771..10727)
                     /locus_tag="ACG84Z_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9162504.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10893..11699
                     /locus_tag="ACG84Z_001660"
     CDS             10893..11699
                     /locus_tag="ACG84Z_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162505.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            11696..12685
                     /locus_tag="ACG84Z_001661"
     CDS             11696..12685
                     /locus_tag="ACG84Z_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFP9162506.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            12682..13686
                     /locus_tag="ACG84Z_001662"
     CDS             12682..13686
                     /locus_tag="ACG84Z_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFP9162507.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13818..14360
                     /locus_tag="ACG84Z_001663"
     CDS             13818..14360
                     /locus_tag="ACG84Z_001663"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFP9162508.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            14380..15078
                     /locus_tag="ACG84Z_001664"
     CDS             14380..15078
                     /locus_tag="ACG84Z_001664"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFP9162509.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            15099..15311
                     /locus_tag="ACG84Z_001665"
     CDS             15099..15311
                     /locus_tag="ACG84Z_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFP9162510.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            15311..16273
                     /locus_tag="ACG84Z_001666"
     CDS             15311..16273
                     /locus_tag="ACG84Z_001666"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFP9162511.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            16291..16686
                     /locus_tag="ACG84Z_001667"
     CDS             16291..16686
                     /locus_tag="ACG84Z_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFP9162512.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16849..17214
                     /locus_tag="ACG84Z_001668"
     CDS             16849..17214
                     /locus_tag="ACG84Z_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFP9162513.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            17211..19022
                     /locus_tag="ACG84Z_001669"
     CDS             17211..19022
                     /locus_tag="ACG84Z_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFP9162514.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(19084..19251)
                     /locus_tag="ACG84Z_001670"
     CDS             complement(19084..19251)
                     /locus_tag="ACG84Z_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFP9162515.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            19500..20489
                     /gene="galE"
                     /locus_tag="ACG84Z_001671"
     CDS             19500..20489
                     /gene="galE"
                     /locus_tag="ACG84Z_001671"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFP9162516.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            20501..21985
                     /gene="galT"
                     /locus_tag="ACG84Z_001672"
     CDS             20501..21985
                     /gene="galT"
                     /locus_tag="ACG84Z_001672"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFP9162517.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            22009..22989
                     /locus_tag="ACG84Z_001673"
     CDS             22009..22989
                     /locus_tag="ACG84Z_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9162518.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            23180..23902
                     /gene="tsaB"
                     /locus_tag="ACG84Z_001674"
     CDS             23180..23902
                     /gene="tsaB"
                     /locus_tag="ACG84Z_001674"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFP9162519.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            23886..24428
                     /gene="rimI"
                     /locus_tag="ACG84Z_001675"
     CDS             23886..24428
                     /gene="rimI"
                     /locus_tag="ACG84Z_001675"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFP9162520.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            24435..24899
                     /gene="rimI"
                     /locus_tag="ACG84Z_001676"
     CDS             24435..24899
                     /gene="rimI"
                     /locus_tag="ACG84Z_001676"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFP9162521.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24896..25912
                     /gene="tsaD"
                     /locus_tag="ACG84Z_001677"
     CDS             24896..25912
                     /gene="tsaD"
                     /locus_tag="ACG84Z_001677"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFP9162522.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
BASE COUNT         8622 a         4549 c         5491 g         7791 t
ORIGIN      
        1 acattgtcaa tcaatgacta attttacaaa ataaatatta tccaagaaga ccacttagat
       61 attgacctcc ataaatcaag gccatactat ataagaaaat cgacagtggt ttagcaatca
      121 aaatgattag tgtatatcgt ttcactgaca tgtttgtcaa tccagccatc aaacataacg
      181 catcgtcagg agcaactgga agaaaaatag ctagagcaaa cagcttctca aaacggtttt
      241 gattatccag ccagccaata tatttgttat atgtcttatc gctaatcatg gaaagtatga
      301 atggctttcc ataacgacgc cctagcagaa aaatgataat cgaaccaatg cagattccaa
      361 tatagttata gataaatcca gcataagggc caaatatcag gacaccagct gcagtactga
      421 tccctccagg aatgattgga ataactactt gcaggatttg gatgaagaca aaaataatcg
      481 gtcctaaaat gatggaatca cctactaatc ctcttaacgc attcaaatct ttgaaaacac
      541 ctaaattaat aaaataaatc gtcagcgcga ttgataggcc taatccgata atggatatga
      601 aatttatcag ttttcgagag gcagcaatat tcattattca tcaactcctt agaggttctt
      661 tgttaactat actttactag aaaagcaact aactgcgcca ttttttgata tgacagaaaa
      721 caaacaattt tgtaagttca tcataagtat aaaagattga tctcaaaaaa acatccaact
      781 aaagacttat ttaataactt gtttttttta aaataaaaaa agcgttagca actatgctta
      841 aaaagcatat cgactgaata aactaagcat tggacaggct gaaagactac atttaaaatg
      901 aaatgcgaag aaacaataga aaataaagtt gccttagaac catagttgaa tcacctaaca
      961 gtcgtgaagg gagaataaga gaaatggcag aaaaacaaac cgcaggacga gatcaattag
     1021 gagattttgc accaaaattt gcagaattaa atgatgatgt tttatttgga caagtatggt
     1081 ccagagaaga attatctgct catcagcgta gtatcatcac catatctgca ttaatttcag
     1141 gaggaaattt tgaacaattg ccagctcatc tgaagattgg caagcaaaat ggcattacta
     1201 gtgaagaaat agcagaaatc attacccatt tagcttttta tgtagaatgg ccaaaagctt
     1261 ggtcagcttt tagtttagca aaagaaatct atttagaaga aaatagcgaa gataagaaag
     1321 aggcgtaaat gatgacaaaa cacgaagaaa tacacaatgg cgtgattttt ccagcaggtg
     1381 aaaaaaacga agcttacgct caagtattta ccgggcaaag ctatctgaat atgttagtga
     1441 atgatcccga agtttctgtt ggtgtaggta atgtaacttt tgaaccaggt tgtcgcaatc
     1501 actggcatgt ccatacagac ggctatcaaa tcttacttgt gaccggagga gaaggctggt
     1561 atcaggaaga aggaaagcca gcaagacgat taatggctgg agatgtcgtc gtaacgcaca
     1621 aagggattaa acattggcat ggtgcgacaa aagacagttg gtttgaacat ttggcgatca
     1681 ctgctggtaa ttcagagttt ttagaacctg taacagatga agtgtatgaa ggattggaaa
     1741 atcaataatg tcaagcttga acagctcctg aaagtagatt ttaatcgaac tttcaggagc
     1801 tgcttttttg attcagtctt ttataaatag aaaatagggt taataatagg aatgagaagc
     1861 acgtcgaaag atcttaatat tgataatcgg ctgggcatac atgatttcca cgtcatcaat
     1921 caaactacct aacagatgat aatcttcccg atcatgtcgg ggattaccta atagttcttg
     1981 atagtagatt tccatactag ggtcccgagg attgttcagc aaatcagcaa gtacatctaa
     2041 atcttctggc tgagtttctg ccgtaccctg tatctctatg aaaagccctt cctcagcaaa
     2101 ttctactcca atacgtattt cagttatttc atgggaatat aaataagtaa gaagctcatc
     2161 gatgattctt tttgataatt ctttttccaa gtgtcttttt ttcctttctg acagcggtaa
     2221 agttatctag tatcggtaca aggatacctg caacgaaacc agttgaaaaa ccactgttat
     2281 atagatttag tcctccgtgc aaagtgctga cgttatggac aagagcaata tgtagcacac
     2341 cagctattac accgtaaaaa ctgccgtaaa aaccgcttat gggcgcaaga cctgtcccaa
     2401 acacagctgc aacaagcatg ccagtactgg tgatctcatg aaaagttcca aacaaagaag
     2461 caataaatat tccgactagt atcggaaaac tgttttttaa atgacaacca aaagcactga
     2521 aacccaccgc agataaaata gcaccgatga caggtccatt taactgaccg ccaaccagca
     2581 aaacataaga agacagcatc agaccaacta agcccatgtt gatcaaagta gcaccaatac
     2641 cagaattagc aatgaaatca gttgtcaatt ttccagatga atcgaaaatt tctcgaatcc
     2701 ccgaaagccg aaaggaatta taatagaaac caattccgac tgtcagcgaa aaaaagccaa
     2761 aaataatcca aatgagagga aagtgatatt cattgaaaac caatgtattt tcgacgattg
     2821 aatagctgaa taacctcaaa acagcagtaa aagtcatcgc aatcaaccca gaggtgaatc
     2881 caatattata aagtgtgaat ccacgatgga aaactaaagt ttgagcagct aagggcggaa
     2941 gaagtatacc aattgctatg ccagctaaat tccccaataa aatacctatc agtaaaggaa
     3001 aacgcatacc aaaagtgata taactaacga ccggtgataa tacgctacca aacagtccga
     3061 tcatgatgta ctgagaaaaa ggtttattga caaatacagc gtatagatac acacctaaaa
     3121 tgattgagat agaattataa aggtttttgc caaaaaaaga gaaaccggta actgttagaa
     3181 tcgaagcaaa taagggaccg tttaaaatca ccttgtgccg ataagctaaa agcacagaaa
     3241 gtaaggtcaa aatccctaca tttatgaatg cgcttccgaa aacacctaaa gcaaaataat
     3301 ctgtcaaaag attgcttggc gaggtaagaa tagttagcaa tccactccaa ttatcagtag
     3361 gagtattaga aagcaagcca ataaaaagaa aaaaaacacc tgtaaaacca agataaaaat
     3421 actttctttt ctgtgaaacg attcgttttt gaggatgaat ataaataacg tcagtttcgt
     3481 tttccattac acaccttctt tttcattttc tttaactata acttgaaatg aaagatttgg
     3541 acaactatca tttaggtcaa aactaaaaat gtaagggaac ccattgaatt taaccaaatt
     3601 tttttaattt tgcaaaaaaa agttaaagaa gactgaaaaa aatttaaaat ataacgtttt
     3661 gagtaaaatg tttgcaaaaa atgctaaaaa tagggtacaa taaaacaaca tatactgcag
     3721 taaagaagtg ggggagtttt aatgagaaga aaagtctata ccaaggatca aattctaaaa
     3781 gctgcttatg atgttgttgc aaaggaaggg tttaaaggat ttactgcgag aaatattgct
     3841 aaaaagatgg ggatttcgac acagccgatt tatctggaat tcaaaaacat ggaagattta
     3901 aaaaatacgt tgctggattc tatctttgaa caactaaaag aagatgtttt ccctattgaa
     3961 cgtactggtg ataaaatcat tgatctcggt ttgaactata tctactttgc aaaaaagcat
     4021 catagtcttt acatggcatt gtacattgat gaacatgggg acggaaagaa aatgcatgat
     4081 ttttcataca attatttccg tgaaatagtt aaagaagatg aaagatacaa tcaattatcg
     4141 gatgaatatg tcgatgctct gcatactggt acatgggtag cagtgactgg cttagcgtca
     4201 ttgatgtcat caaacatcat gcatccaaca gaagaacaaa tcattgcact gatcaaacgg
     4261 acaattgact cgattttagc attagataat cctgaaataa tcagatagtg ttctatcagt
     4321 atgaatttga tcggtaagtc cgttggctgc aaactgtcaa tggacttttt tgctaaaaaa
     4381 agcgatttct gttatttatc tattagaaat aggcttgaca tttcgtgaaa aaagtttaaa
     4441 aatagtactt acggaaggtt ggcagagtgg taatgcaccg gactcgaaat ccggcgaacc
     4501 ggctaatacc ggcgcgcagg ttcaaatcct gtaccttcct tatatcaacg attagaggtt
     4561 gtgaagaagc tgtcctgcat caagtaataa gaacggccaa acaaaaatag cttttcctat
     4621 tttttcgttt ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttgttcgga
     4681 ataaggggct gtgacaagac ttttgtcaca gccccttatt gttgtacttt taacctacaa
     4741 tattttttga ttccccctga gtactatttt ttataaatgc tagtaaatca atcttctttg
     4801 gccttttttt tgataaaaaa aaatactaga tgtaagataa aagtgtaaaa acgatttgtt
     4861 ttaggaggga aaacgatgtg taccgcaatc acttatgcaa cgaaagacca ttattttgga
     4921 aggaattttg attatgagat gtcttataat gaagtagtca ctattactcc aagaaattat
     4981 cgtttcgatt ttagaaaggt aaaaaattta gataaacatt atgcaatgat aggaatagca
     5041 gctggggtat ccaactatcc actctattat gaggctacaa atgaaaaagg gttgagtatg
     5101 gcaggactga attttcctgg caatgctgat tataaagaat tacaagaagg aaaagataac
     5161 gttgcaccat ttgagtttat tccatggata ctagggcaat gctcaaccat agacgaagct
     5221 aaagaattat tggctactat caatctagtc aatatcgatt ttagtgaaaa actacccttg
     5281 tcacctttac actggttatt agctgataaa gaaaaatcga tagtaattga aagtatgaaa
     5341 gatggacttc atttatatga taatcctgtc ggtgtgttga caaataatcc gccatttgat
     5401 tatcaattat ttaatctgaa caattatcgc tcgctatcaa atggaacacc agaaaatcat
     5461 ttttcaaacc agatcagctt gaatgtttat agtcgtggga tgggaggatt gggcttacct
     5521 ggagatctct cttctgtttc tcgatttgta aaagccacat ttactaaaat gaatgctgca
     5581 tcaggtgatt cagaatctga aagtatcagt caattttttc atatactagg ctcagtcgag
     5641 caacaaaaag gagtatgcga tactggagaa ggaaaatacg aatatacgat ttattcttct
     5701 tgctgtaacg ttgataaagg gatttattat tatcgtacgt atgaagacag tcaaattact
     5761 gctgtaaata taaataaaga agacttggat cgtcatgaat tggtcagtta tccagtcata
     5821 aaagagcaac agataaacta tgtcaattaa ttaatgaata gatccgtttg gtatcatatt
     5881 ttctgataca gtcataatta gacacgatct ttaggtcgtg tctttttttg ctgttttttt
     5941 tggaaatagc atccactaat atttttttaa cacgaagaga ataaggtagc ctcaaaaaag
     6001 aaaacatggt aaattagata ttgggacttt attttctgta aaaacagaaa ctttcatctt
     6061 ttgttttcac gtgacgaaat tgtaagagag aaaatattcg tccgctattt attctatgat
     6121 aagatgcata tgaatgaaat aaacagtaat tttatattag gatgtgaaag ttaaatgtgc
     6181 ggtattgtag gttttgttaa cgacaaggac aacaaaaaaa caattattaa tacaatgatg
     6241 gatcgaatcg ttcaccgtgg acctaatagt tcaggagaat atatcgataa acatgttgct
     6301 ttaggattca gaagattaag tattattgac ttagagggcg gtactcagcc tatttacaat
     6361 gaagatcgga caaagatcat tatttttaat ggcgaaatct ataattacca gcctttgaga
     6421 gaagaattga ttgcagctgg ccacgttttt caaacacatg cagatacaga agtccttttg
     6481 catggttacg aagaatgggg aacagaatta ttgcaaaaga tccgcggaat gtttgctttt
     6541 gctatttggg ataatgaaaa gaatgagtta ttcggtgcaa gagaccactt tgggatcaaa
     6601 ccatattatt atgcagaaat gaacggaaca tttatgtttg gttcagaaat caaaagtttt
     6661 ctgcctcatc ctgattttaa caaagaattg aacaaagaag cgttgaaacc ttatatgact
     6721 ttccaatatt ctccattaaa cggcgaaaca ttcttcaaag atgtctatcg tttgcctgaa
     6781 ggccattatt atacgtataa agatggaaaa ctagacattc agcaatattg ggatgcagat
     6841 tttgaaacaa aagaaacgca ttcccgacaa gaatggatcg aaaaaatcga cgaaaccgtt
     6901 caagcttcta ttgaagcaca tacggtcagt gatgtagaag ttggttcttt cttatccagc
     6961 ggggttgatt ccagttatgt aacctctgta ttgaaaccag atcattcttt ctcaatcggg
     7021 tttgatgata aaacctataa tgaagcgatt gaagccagaa aactaaccga actattggac
     7081 ttagataata cagcagcagt gatcgacgga gacatgtcgt tcaaagcatt ccctttgatc
     7141 cagtatcact tagatgaacc tgattcaaat ccttcttgcg tacctttgta ctttttagca
     7201 aatcttgctt cacaaagtgt gcgggtagtc caatctggag aaggggcgga tgaactgttt
     7261 gcgggatacc aaacgtatgg attccatacg aattcaaaat tcatccgtgt gattgctcaa
     7321 ggattgaaaa aattaccaaa aggaacacgc tataatttag gacgtaaaat cggaaaaatg
     7381 aaaaatttcc atggacggat ccatttatat gaatcacttg ctcctgcaaa agaatatttt
     7441 atcggtcatg ctcgagtgtt cgaagaatca gaagcatcag aagtgttaac accaaaatat
     7501 caaacagcac catctgtgga tgaaatcatg actgttcatt acgagaaaac agaaggaatc
     7561 aaagatgaag tcaataagat gcaatatgtc gatcttcatc aatggatgcc aaaagatatc
     7621 ttgttaaagg cagataaact ttctatggca agttctttgg aagtccgagt acctttattg
     7681 gatatcgaag tcatgaaatt ggctcaacaa ataccaagta agtttttatt gaatcaaaac
     7741 aacacaaaag atattttcag acaagctgcg aacaaacatc ttccggaaga atggtcgaat
     7801 cgtgtgaaat taggattccc tgtgccaatc aaagcttggt tgaaagaaga acacggctac
     7861 gaacaagtca aagcattatt cgaagcagat tttgcaaaag aattttttga tcaagaaaaa
     7921 atcatgaagt tgctagatga ccatcacgaa ggacgtaaag aagagcaaag aaaaatctgg
     7981 acaatcttca gtttcttgac atggtataaa gtctactttg tagatgaaac gattccgcaa
     8041 gcagaagcaa tcgactatgt gactgtttga tgaaaatcaa atatcaataa aaaagaggtt
     8101 ttctcctacc gtttaacact gagtgataag aaacaatttc aaaaaacagc tcttcccgtt
     8161 ttatagatat tatgacttat ggttcggagt tggcagagga acaccattgt ttcgaacata
     8221 agggggttgt gacacgattt tcgtcacaac ccctttacat atgttcaata atcgatttct
     8281 ttttcttttg tcccatcttt tttataaatg aacaaagttg attctttgtt ttgtgctact
     8341 tgctttcctt tttcgattgc ttcttttttt gtatcaaaat ggttgcttgc cttttttgcc
     8401 cctttagatt tcacgatcca ttgttcttcc tcatattcta cgatcacatc tgaatcaagc
     8461 agttttccag cacgaggatt cgtatcgtgt tcatccgtct tgcttggatt tttttctttt
     8521 tcgaaagttc gtttttctga ttcactagca tcttcatacc atttttttgc ttgatcaatg
     8581 gcaattggga tcgcacggtt atcagggtac ccttcatcta ataatgcatt tgcgatgtcg
     8641 attgcttttt ttcttgtcaa tttatctaag tttttcattg atgcaggaaa gtccttcatg
     8701 ttccatggca tattagtatc cccctttatt aaaaaacata atctatataa acaagtgtaa
     8761 gggtatttat acaaaaagaa aaagattttg tttgagaagt aaaaccgttg tatttatcgt
     8821 caagtagttt tacttaacaa aatcgtgaaa aacactagca atctagaaaa aatcatggta
     8881 agataatcaa gtctgagagt catcttagag gattcttgta aaaatgggag ggaaaaacat
     8941 gcgcgtaaac atcactttag agtgtacttc ttgtaaagaa cgtaactatc taacaagcaa
     9001 aaacaaacgt aacaatcctg atcgtttgga aaaacaaaaa tattgcccac gcgaacgcaa
     9061 agttactttg caccgtgaaa caaaataatg tttttaaagt tctcaattcc ttgctggtca
     9121 aagaattgag acttttttta tctcaaaaca tctaaaatca taaggagcgg ataatatgtt
     9181 tatttccatg tgggcacaag ataaaaatgg tctgatcggc aaaaatggtt tgttaccatg
     9241 gcgattgcca aatgatatgc gtttctttcg cgaacataca atggatcgaa ttttagtgat
     9301 gggaagaaag acctatgaag gaatggggga tctttcactt ccttatcgcc atatcatcgt
     9361 gttgacaacg caaccaaatt ttcgcacgaa agaaaatgcg gaagtaatgc attcgatcga
     9421 tgaacttttg tcgtatagtc aaacgatctc agaagatatc tatgtttcgg gtggtagtcg
     9481 gatttttcaa gaacttcttc cttacactgg tcggatctgg cgaacattga tcgatagcac
     9541 gtttgaaggc gatacgtata ttgggaatat tgatttttca gacttcgccc ttatagagga
     9601 gtatgagggg ataacggatc aagaaaatct atatgcccat cgttttcaaa aatgggaaag
     9661 agtaaaaaat agggttgctt caaaagaaga ataaaatcta tgcgtctagt ttgttaataa
     9721 gaaaaaaagc atctcacgac taatcgtgaa gattcttttt ttagttaaaa tcaatttagt
     9781 ttttctttga tatcattgac catttcctga ctggcaatag gtccgttata tagccaacta
     9841 gattcaggtc cgaattgcag tacatgattg tctgtcactg ctttaagatt cttccagctt
     9901 ggttcattga acatggcagc atctttgtca ctgttcacaa ggatgatgta gtcagcatct
     9961 aattcagcta gcttttcaga ggaaacagca gaccagtcag aagtggcttt tttggagacc
    10021 tcttccacta gatcaggaac accaaattcc agatcgtcgt atacgattct tccacttgac
    10081 cgatttttgc tgaccataaa ggctgagttg ttggtcaccc acaacactgc agctgtcttg
    10141 ttctcgattt tatctgctag ttcttctcga gttttcttga tggatttttg ataatcggaa
    10201 atgatttttt ctgcctcttt ttcttttgcc aaagctttgc cgacatcttt tagttgttct
    10261 tcccatgtga catctgttcc gttttttaca acataagttg gcgcgatttt gctatattgt
    10321 tcgtatttcc cgccttcgac agtagcggaa gaagaaatca acagcaaatc aggctcaaag
    10381 cttaacactt tctcataagg aaggtcataa gaaatcgttg ggacatcctt taaatcatct
    10441 tgcagataat cttgaatgga accactgcca acagtccact gggcgatagg tttttcccct
    10501 agtgcaatca gatagtcttc taagtaactg ccgatgatcc gtttgggcgc gtttggaatc
    10561 tctactttat gtccaagtgt atctgtgact gtatgagtac tattggatga agtcgtcgaa
    10621 ttggcagttg tagctgtttc tttatctgaa gagggggagc aagcgctcag tactccagcc
    10681 agcagcaata tgctagataa tgtgaatact tttgttttta atttcatttc tttcctccta
    10741 acataattga gaatctttct cattggttat tattcctgat atttcgaacg ctgtcaaccg
    10801 cttcatttgg ctatagatat gaaagtagcg cttgacgaaa tgttgaaaca gcgtcataat
    10861 tgagaatgat tttcagcgaa aggatgggtg aaatgacgag attaagagca gctgacattg
    10921 cagccggcta cgaaaacaaa aaaatcattg aaaacatgtc tgttacgatt cctgaaggga
    10981 aaatcactag tttgattggg ccaaatggaa gtggaaaatc tactttattg aaaagtttta
    11041 cccgtatact acctgtgaaa tcaggaaaga tcattgtcaa taactctgat atctctacat
    11101 acagttcaaa agaacttgca aaaaaaatta cattattagc acaaactagt gaacacccta
    11161 caggtatgac agtagaagaa gtagtatctt acggacgata cccttatcaa aaactgttca
    11221 gtggcatgga cacgcaagat catgaagcaa tcgagtgggc gttggatgct acaggtctag
    11281 ctggatttcg tatgcgggat atcgcaacgc tgtctggtgg acaaacccag cgtgtctgga
    11341 tcgctatggc gcttgctcag gaaacagata tcttgatctt ggatgaaccg acaacatttt
    11401 tagatccggc acaccaatta gagatcctac agttattgac tgaaatcaat caaatgaaac
    11461 aaacaacgat cttgatgtcg attcatgaca ttaatcatgc ttcacgtttt tcagattatt
    11521 tattagcaat gaaaaacggt aagttgatca cagaaggtac acctgaagaa gtgatcacaa
    11581 aagagtgtat gaaaaaaata tttgagattg atgcaacgat tgtcacgctt ccaagaacaa
    11641 ataaaccagt ttttctaacc tatgatttgt tgccaaaaga gcaggaggat caattatgag
    11701 gactatgaag aaaaatagac tcctgctttt ggtctgtttt gttcttttga ttattttttt
    11761 tgttgctctt tcaaatggcg cagcgactgt gggaaaagca gatttttggc aggcgttgtt
    11821 tgattttgat agatcaaaac aaagtcacca aatcatacga aatattcgtt tgcctcgtgt
    11881 ggcgggagca tttcttgtag ggagttgttt tgcattgagc ggtgcattga tgcaaggagt
    11941 gacaagaaat cctttagcag attcaggctt actaggaatc aacgcgggtg cttcgttggc
    12001 aatggccctt agttttgctt tttggcctaa agcttctgat ttttctgtgt ttctaatgtc
    12061 attggcaggt tcttttgctg taactttgct cgtatttggt tttttgcagt tttcgaaaat
    12121 gggcatgaat cctttacagc tgattttagc tggcgtagct attagttctt tttttactgc
    12181 tatcagccaa gcacttaccc aattctttaa tctgcagcag gatcttgctt tttggtttgt
    12241 aggcggagct gccaatatca catggaaaca attagcagta ttgtttcctt tatatatact
    12301 tgctgttttg gtttcttttt cattaggaaa agcaatatct ttgattcatt tgagtgaaac
    12361 acatgcatta gctcttggaa gtcatcctaa acgaacgcgg ttgattgttt tctgtctagt
    12421 tgcagtgtta gcagccattg ccgtttcgtt agtcggacct gtttcattta ttgggctgtt
    12481 ggttccgcca gttgttcgcg gaatggttgg aacggactat cgttatgttc tacctgtctc
    12541 ttttttagtt ggcggtggat tggttatgtt ggcggatttt acagcgagga tgatcaatcc
    12601 cccttttgaa acaccttttg gattagtcat tgcattgatt ggcgttccgt ttttactgat
    12661 acaagtaagg agggaacaac ggtgaaaaaa atatattgga cgttctattt cttgcttttt
    12721 gtacttgtca tcctgtctat aggtagttta atgattggta cgccttttat ttacctggat
    12781 cagctttttg ccacgttcat agggaaagaa tcatcttctt tggcgctgat tgttagagaa
    12841 tttcgagttc ctcgattact gatcagttta ttagcaggag cttgtcttgg cgtttctggt
    12901 tatatcttgc aaggagtaac aagaaatgaa ttggcagatt ctagtatatt gggcattaat
    12961 gccggagcag gatttttagt gatgctttat ttaggtttct tttcgcacta ttcgctgccg
    13021 tttctattgc tagttgtagc ctttctaggt ggtgttttag ctgcttgctg tgtctatctt
    13081 gcggcctatg atcgaaatgg ctttttgggt atgaatcgaa tcttattgtc cggtattgcc
    13141 gttaatgccg gcctttctgc attaacattg ctatgcacga tccaattatc taaggaaaat
    13201 tatggatttg tgaatgcatg gttagcggga tcaatctggg gtgcgagctg gccttatgtt
    13261 tgggcattgc ttccatgggc ggttatctta attccgctag gaggacttta tgcacagagg
    13321 attggattgc tatcatttgg tcaagaacgc gcgcaaggat taggccttaa cgtggctaaa
    13381 agtcaaaaaa tccttttgtt gttagctgtt gctttggcaa gcggtagtgt agcggtgaca
    13441 ggtagtttat cttttgtagg actactagct cctcatgctg cgaagctagt cgtacgtaaa
    13501 gaaaataact ggacctttgt tctgagcggt ttgttcggtt ccatttttct gcttagtgca
    13561 gatatggttg ctagagtgat tctaccaagt ggggaagtac ctacaggaat tttgattgcc
    13621 ctttttggtg cgccatattt tctgtatgca ctttttatca gacaaaaaca cgcgctgaac
    13681 agttgaaatt tattaaaaaa ggaaggccaa tcatttctag gtcttctttt tattctattt
    13741 atgcatttat ttgaaagttc gattgctatt tttctttttt tcctatacca ttttatgaga
    13801 gaaggaaggg tgagtttttg gaccaattga aagtaagatt acgccggaaa ggaatcgaaa
    13861 agctgaaaaa tctggccaaa agtggcaaga aaaaggaaaa agaacagcga atctataaac
    13921 agctattcgc cagcgagtac tggaagtcag caaaagtgat agggacgact ttatcgaatg
    13981 aatttgaact ggatacacag ccggttatcc aacgagcaga aaaagaacaa aagaaaatag
    14041 ttgtacctaa aactttgccg aaacgtcaga tggcgtttta tgaaatggat gaacagtccg
    14101 ttcttgtacg ttcgagtttt ggtgttcttg agccacaatc agagaagctc tatttgccgg
    14161 agatgatcga tctcctcatt gtaccaggta ttatctacaa tagagccggt tatcgaatcg
    14221 gttttggcgg tggttattac gaccggtatt taaataattt tcataaaaaa acatgtagcc
    14281 ttgtttttcg tgaacaattg aatgaacaat ggcaaccgga gagctttgat cagaagatcc
    14341 aacaattgtt tattgactaa aatgaaatgg gaggttttca tgaattatca acagcaaata
    14401 aaattgcgtg catggttaag acgaccgtta tggacctatg cttttttagg gatacagaca
    14461 gcggtcttcc tcatgatgga attatttccg cgacttgaga tcccttatta tgccggaatg
    14521 tatggtcctt atcttgttca cttcaatgaa tggtggcgtt tagtgacacc aatcttcatc
    14581 cattttggac tgatgcattt cgtaatgaac tcactgatac tgtattttat ggggcagcaa
    14641 atcgaggcaa tctatggcca ttggcgtttt ttcttgattt atatgttcag cgggataatg
    14701 ggaaatacag caagctttgc ttttaacgaa gcgaatgttc tgtctggtgg tgcgagtact
    14761 tcgatattcg gtttgttcgg tgcgttgttt atcttagggt ttcattttaa acataaccca
    14821 gcgatccagc agctagtcag acattttctt ttatttattg tgttgacatt tgtttttggt
    14881 cttctggata cctctgtaga tgtttgggga catgtcggtg ggctaattgg cggattagtg
    14941 ttagggaatg ttttgggtct accgaaacaa cagacaagct attcgataca ccaaaggatt
    15001 ctttctacac tagtttttgt atttcttttt gtaatatgta ttttactggg tttaaaaaaa
    15061 tatggtttac ttgtataata tgaaggaagt gcttaaagat ggagagctta tatgatgtac
    15121 agcagctgtt caaaaaattt ggcatcttta tctatgtggg tgcacgcatc tatgacattg
    15181 aattaatgac tatcgaattg cgtaatctgt atgatagccg tttgattgat catgatacat
    15241 acatgacagc gtggcgcata ttaaaaagag agcaccgaat tgaagaaagc cgaaagaaag
    15301 gaaatttgta atggacaaga agattattgg gattgattta ggtggaacaa cagcaaaatt
    15361 tgcaatttta acaccagaag gagagattca acaaaaatgg agcatcgata ccaatatttt
    15421 ggatgatggt aagcatatcg ttcctgaaat cattgaatca atcaaccatc gtttgaattt
    15481 atataatatg aaagccgaag actttatcgg aatcggcatg ggtaccccag gaagcgtgga
    15541 cagcgaagct ggaacggtta ttggtgcgta taacttaaac tggacagaag ttcaatttgt
    15601 gaaaaaactg atcgaggcag gaacaggaat caaattcgct atcgataatg atgcgaatgt
    15661 tgctgcttta ggtgaacgat ggaaaggtgc tggagaaaac gatccagacg ttgtattcgt
    15721 tactctagga acaggtgttg gcggtggtat cgttgctggc ggaaatttga ttcacggcgt
    15781 gagcggagca ggcggagaga tcggccatat cactgtggat cctgaagggt tcgaatgtac
    15841 ttgcggtaaa cgcggatgtt tagaaactgt gtctagcgct actggtgtgg tacgtctagg
    15901 tcgttacttg gcagaagaat acgcaggaga ttcaaaactg aaagcaatgt tagacaacgg
    15961 tgaagaagta acaagtaaag atatctttga aatggctcaa gaagacgatc cgtttgcatt
    16021 gatggttgtt gatcgcgtat gcttctactt aggtttagct tgcgccaact tggggaatac
    16081 attgaatccg tcaagtattg tgttaggtgg aggagtatcg gcagcaggag aatttttacg
    16141 tagccgtgta gagaaatatt ttaaagaatt tactttcccg caagtaagag aatcaacaaa
    16201 aatcaaatta gcagagcttg gtaatgaagc tggtgtcatt ggtgctgcct cattagcctt
    16261 gaaatttgct taaaaaaacg gaggcattac atggttttat gggtaattaa tatcattttg
    16321 ctattgattg tgcttgcaat catcttttgg gaagtctatc tacgagtaat ggccaagcgt
    16381 tcagcaacga ctttgacaga agaagaattt cgagaaggaa tgagaaaagc acaagtaatc
    16441 gatgttcgcg aaaaagatgt gtttgatgct gggcatattt taggtgcaag aaacatccct
    16501 tacactgttt tgaaagattc attaggatct attcgaaaag accagcctgt ctatatttac
    16561 gatcaaaaga aaagcttgag catccgtaca gcaaataaat tacgtaaagc aggttatcaa
    16621 gagatttatt tacttaaggg tggatatgac ggatggtctg gaaaaatcaa aagtaaaaaa
    16681 gtataaaaca gatgattgta tgacagcttt aaaaaccgaa tcaatcatta gattttgacc
    16741 aagatcacat gaacggcgca atggatagtt gtgccgttca ttttttttat tttgtgctat
    16801 tatctacata tataagctaa gcgaaaaggc agaaagaagg aaacaactat gatcaaatta
    16861 aaacgtgttt accttgatgc tgaaaaagag gatggctata gaatactcgt ggataggttc
    16921 tggccacgag gaatttcaaa agaaaaagcg cagttagatc tgtggttgaa agaaattgca
    16981 cctagtaatg aagcacgcaa aacttttgac catgtaccag aacgatttgc ttcatttgca
    17041 aagaaatacc agcaagaatt gattttcgaa gaagaaaaga agcaagctat ttttaaactc
    17101 agtcaactta tgaaagaaca tccagtcatt acttttgttt atggtgcaaa aaatgaacat
    17161 cagaaccatg ctgttttatt gaaaaaattt atcgaaatgg aggcatgcaa atgaaaatag
    17221 ggatcattgg tgccggacct agaggattaa gtatagcaga aaggattctc cataataatc
    17281 aggacagaca ttctcttgaa ctttttcttt tcgatcccaa tggtcctgga ggtcgagttt
    17341 ggcggttgaa tcagccaccg gagttattaa tgaattctgt ttctcaacaa gtgacgcttt
    17401 ttacagatga aacattgtcc agtggaggat tggtaacaca gggacccaac ttgtttcaat
    17461 ggagtaaagg acctgctaca gattatatcg aacagacggt aaccaaaaat aagcaactaa
    17521 ttatagaaga aatcaatcgt ctggaaaaag atcagcaatc tactcgatgt ttatacggac
    17581 tctatcaacg ctggtttttc tcaaagttgc aagaagaatt tccagcttct attcagtttg
    17641 tttattcttt agtaaaaaaa gtcagcaaaa gaaaagatgg ttatctttta cagacagatc
    17701 agcaaagcta ttctatcgat cagcttgttt tagcaagcgg tcactgggaa aatgatgaga
    17761 cagaagaaga aagagtgtgg gtagactacg caaagaaaaa tgatttactg tatcagcttc
    17821 cttctaatcc tgcagatgtc gatctttcga agataccgcc taaagaaaat gtctttttaa
    17881 gaggtctagg cttaagtttt tttgattatg tcggattgtt tacagtatca agagaagggc
    17941 gcttcgagaa cgaaaaagga aaacttgtct atcatccatc aggcaaggaa ccgattgtat
    18001 acagtggatc aagaaggggg ctcccttatt accctcgagg aagaaaccaa aagcaaggcg
    18061 gatcaatggc atggccacgg ttactaacaa aagaaaacct ggagcaatgg catcagtcgg
    18121 gatttttgac tggcgaaaca ttttttgact atctgaaaaa agacgttgag ttgttttatt
    18181 acaagaaaat catcgaagaa tatcatttgc cgattccaaa gaaaaatttt gagcatgatt
    18241 ttctctccct ctcttcagag gagtgtctcg gaaagcatcc agcactaatc ccttatagat
    18301 gggattggtc gtatttagaa attcctctta cctatcagga tgagtccttt gcagaagcta
    18361 gccgagcatt tattgaaggg cagataaaag aagcggaaaa aggcaattgc acaggagcat
    18421 ttgcttcaac atttgatgca ttaaaagact ggcgtgatcc aatccggcag gctattgaat
    18481 ggcacgtttt ttctgcaaag gaatacaaag aaatactatg gggatggttt actcatctaa
    18541 atagcttttt aacgatcggt ccgccagtca ttcggacgaa agaattagca gcactgatag
    18601 atgcgggtat ttttcatttg ttcgaaccgc catttgatat tcagcaaaag cacaaccgct
    18661 atgttatttc tctacaagat aaagaaatca gcagtcgcta tttgattgaa gctcgattgc
    18721 cacaaacaag cttttctcgt tcaagtaatc ctgtcataaa aaatttgaag gaaaacaaac
    18781 ttgttcgccc tttttcattt tcagataata caggaagtta tcattcagaa gctatagatg
    18841 ttgagcgagg tacgaatcgc gtgattgatg cttcagggga aatccagtct gacttttatt
    18901 gctatggaat acctgttgaa ggtgtggatt ggctaactgc agcagtagct agaccttata
    18961 cagatccatg gaatctgaga caggcagata aaatagcaca acttatattg actgacaaat
    19021 aaaaatacgc atgatgactt atctgttctt tcacaagtct tcatgcgtgt ttttaaataa
    19081 ttattaacga gaaacgcgtt tgcgcattgc ttttttacgg ttttcttcga tcattgcttc
    19141 tttttcgtca attggatcga tcactgtttt tttcacagaa gcgaccaaac cagcaacggc
    19201 agcggctgtt gccagacttc ctactaatat tccagataca aattttttca ttgaatccac
    19261 ctcatttatt atttgttata tctattatgg aacaaaagag aaaaaaaggc tagttttacg
    19321 tttgtttgta aacctttgca aaaaatcctt gaaaatgttt actaaatgtt ttattataaa
    19381 tttaccatat gaatttacga aattttactt tgtttgtttt caccataaaa gtaaacttcg
    19441 tttttttaaa ttatatataa tcaacaaaca caattttact aatcaaagga gtgtttttta
    19501 tgacaatttt agtactaggc ggagccggtt atatcggttc gcacgctgta gaccagctag
    19561 ttcaaaaggg gtatcaagta gctgtggtag ataatttgct cacaggtcac aaacaagcag
    19621 tacatccaga tgctcatttt tatgaaggag acatccggga taaagaattt ctacgttccg
    19681 tatttgaaaa ggaaccgatt gaaggagtaa tccattttgc tgcaagctct ttagtaggag
    19741 aatctgtcga aaaaccattg atgtatttca acaacaacgt atacggtatg caaatcttac
    19801 ttgaagtcat gcacgagttc aatgtgaata aaatcgtgtt ctcttctact gcagcaactt
    19861 acggagaacc aaaagagtct ccaatcacag aagatacacc agctaatcct aaaaatccgt
    19921 atggtgaaag taaattgatg atggaaaaaa tgatgaagtg gtgtgaccaa gcatatggca
    19981 tgcgctatgt cgctttgcgc tacttcaatg tagccggagc aaaagcagat gcatctatcg
    20041 gagaagatca tacaccagaa acgcatcttg tcccaatcat tttacaagta gctcttggtc
    20101 aaagaaaagc attggctgtt tatggagacg attatgatac accagatgga acatgtatca
    20161 gagattatgt tcaagtagaa gatttgattg ctgcacatat tttagctttg gaatacttga
    20221 aagaaggaaa tgaaagcaac ttcttcaatt taggcagcag caaaggatac tcagtcaagg
    20281 aaatgctaga agcagctaga gaagtgacag gaaaagaaat tccagcagaa atagcaccaa
    20341 gaagagctgg agatcctagc cgattagtcg cttcaagtga aaaagcgaga gaggttctgg
    20401 gttggaaacc tgaatacaca gatatcaaag caattatcaa aacagcatgg gattggcatg
    20461 tcagccatcc aaatggttat gaagaatagg ggaatgagat atgtcaatca gtcaaacgat
    20521 ttgtgatttt gccacacttg cgatcgaagc tggcggatgg atggaaatgg accgcttata
    20581 tttacagaat cgtcttttag ggatggtagg agaagatgct ctagaaagca ttgaagtaag
    20641 accagttaag gaagaatctg tagacttatt ggatcagctt gtcgctaagg caagagaaaa
    20701 tggtgttctt tcagaattgc cagcagaaca agagattttt gaagcgcaat taatggattt
    20761 tctcacaccg ccaccttcag tcgtcaatgc attctttgca cagcactatt cgaaaagccc
    20821 agaggaagca actgagtatt tctttaattt aagtaagaaa aatgactaca tcaaaacaag
    20881 agccatcgca aaaaacatca aatttccggc agagtcggag tatggtgaac tggaaatcac
    20941 aatcaattta tctaagccag aaaaagatcc aaaacaaatc gcagcagaac gcgaggcggt
    21001 aaaagtagac tatcctacct gcatgctttg catggaaaac gaaggatata gaggtcgctt
    21061 gaactatcca gcccgcacca atcaccggat tattcgaatg aatctagacg gtgaaagctg
    21121 gggattccaa tattctcctt atgcttatta caatgaacat tcgatcattt tatcagaaca
    21181 acaccgcccg atgaaaatca caaaggaaac atttgctaga ctgcttcgga ttactgaagt
    21241 cttgcctcat tactttgttg gttcgaatgc tgacttgccg attgttggag gatcgattct
    21301 ttctcatgat cattatcagg caggacgtca tgaatttcct atggcaaaag caccgataga
    21361 aaaacttatc aaactagcag attatccgca agtcatcgca ggagtcgtga aatggccgat
    21421 gtctgtgatc cgtttgcaat caacagagaa aaaattgttg attgaagcag ctaactcagt
    21481 attggaaaag tggaaagcat attcggatga aacagtatct atcagagctt tttcagcaga
    21541 tggtacacca caccatacga ttacgccaat tgcacgaaga agggacaatt actttgagtt
    21601 ggaccttgtc cttcgagaca acaatgtttc agaagaacat cctgatggga tttttcatcc
    21661 acataaagat gtccaacata tcaaaaagga gaacattggg ttgatcgaag taatggggct
    21721 tgctgtttta ccacctcgtt tgaaaccaga actagtagaa gtagagcatt tcttattagg
    21781 agaagaaaac cagatggctg aatatcatcg tccgtgggca gaacaattaa aaaaagaaca
    21841 tcctgatttg acgaaagata cggtcaccga tgtcgtacaa aaatctgtag gtcaggtttt
    21901 tgcacgtgta ctggaagacg ctggagtatt caagcgagat gaaaaaggac aggcagcgtt
    21961 tgaacgattt actgcaattt tataaacgta aaaaaggagg agagacaaat ggcaacaatt
    22021 aaagacattg cgcagttggc aggagtttct cctgctactg tttcaagagt tctcaactat
    22081 gatcctgatc tttccgttgg cttagccaca aagcaaaaaa tttttgaagc agcagaacgc
    22141 ttaaattata cgaaacatcg taaaaatgca gcaaatacta agcaaacgct tcgcctgatc
    22201 cagtggtacg acgatacgga agagcttgaa gatctttatt atttatctat tcgtctagga
    22261 atcgaaaaaa aggcagaaga agcaaacgtt actttattga aagaaacgtg ggattccatt
    22321 agtgatcttc cgacagatgg aacgatcgca ctaggaaaat tcgacgaagc tcagttatta
    22381 gaaatgaaag gatcccaaaa tgccttgctt ttggtagatt ctgacggcac ttctcaagga
    22441 atcgactctc tagttgtcga ctttaagtca agtgttcaaa aagtcattga acattttgtc
    22501 tcccataaag cgcaacatat cgctatgctt gctggaacag aatatacgaa gaaaaaccat
    22561 cagcggctaa aagatcccag aattatggca tttcaacaag ttttggcaga aaaaggctac
    22621 gacgaaggtc caattatcga agcagatttt tctgtcgagt caggatatca agcagtgaag
    22681 cagtatttaa aaacgaatcc gcatgttcct gatgcgcttt ttgcagctaa tgatgcatta
    22741 gcgattggcg cactgaaagc gattcaagaa aaaggtttag tggtaccaga agatatttct
    22801 gtgatgggtt tcaatgatgt cagtgtagcg aaatatgtaa cgccctctct ttctactgta
    22861 aaagtttata ccgaatggat gggagagcta gcagtggaga cgattcttca attaagtaat
    22921 tccaaagcac cggtttcaag aaagattatt gtggaaacag agttgattat tcgagaatca
    22981 acgaaataaa agatggaaaa gctgtgggga aatgaagtga taccgcagct tttttgtgtt
    23041 tcaggaaggg gcaaaatttg cccgccagca gataatcatg tatcattgta ctagttttgc
    23101 ctttggtatt ttcatcctca gaataaaaaa gtatgctaca atggaaggcg agaatgtcat
    23161 agcagaaagg atcaaatata tgattacatt aggaatagat actgcaaacc aaactttggc
    23221 gatcggtgtg gtagaagacg aacaaattct tggacaaata caaacaaata tcaaacgcaa
    23281 ccacagtgta acactgatgc ctgcaatcga ccaattgttt gcagatcttc aaataagtcc
    23341 aaaagacatt gaccgaatcg cggtttctga tggtcccggt tcttatacag ggcttcgtat
    23401 aggtgtaacg acagcaaaaa cgattgctta tacattagat aaagagctag taggagtatc
    23461 tagtctgaaa accatcgcgg ctaattgcat cggtgtggat aaaattattg tgcccatgtt
    23521 tgatgctcga agaaaaaatg tatacgctgg ggcataccgc tggaaagaaa atagattaga
    23581 aattgtactt gaagatgtac atatttctgc ttctgatttg ttcacacaac tacaaaagct
    23641 gaatgaagct atttatttcg tcgggagtga ttgtcacaaa ttcttctatg aaataaagga
    23701 aatattgcct agtgcgatga ttaatacagt tccagcatgg gatattccaa gtggtgtaac
    23761 tgtggctcaa ttaggtgctt tagctgaacc agttgcagag aaacaagctt ttcttcctcg
    23821 ctatttaaaa cgggtagaag cagaagaaaa atggttggag acgcacacac ctggagacga
    23881 aagttatgtt gaaaaaattt agagcgtatg ccagaagctt ttttcaagat aaaatgattt
    23941 atacagaaaa aacaatcgaa caaatcgatc gtcgttacgt actaagagaa ttgactacag
    24001 aagatatcaa agagctgctg gatgtcgaac gagaagtcta taatggcgaa ttgccatgga
    24061 caaaaagtgc ctttatatca gaattgaagt caccgcttcc tcatctatat ctaggtatct
    24121 ttgataatgg aagaatgatt ggttttatcg gttcaagagc gttcggttta gattgccata
    24181 tcacgaatat tgccgttcga ccggcatatc agcgtaaacg aatcggttcg ctgcttattg
    24241 acgaaatcga gaactttgct ataatgaatc gctgtgagac gatgtcatta gaagtgcgta
    24301 tgagtaatca agatgcacaa agactttatc ggaagttagg ttttcaagca acaacgatca
    24361 aaaaaagata ttacactgaa acaaaagaag atgcgttgga tatgataaaa cttttagaaa
    24421 atgagtgaga ttagttgatt tgcagaaaaa aagattttga tgaagcgtac ttggcagaat
    24481 gcgtatggat gattagcgaa aatgcttatc cacatggttc accttggacg aaaatgcagt
    24541 ttttggcaga catccaacag cctcactctg attatctgct tttagttgaa gataaccaga
    24601 tctgtggctt tattggatac tcgaaagtaa tagatgaagt cgagatcaca aatattgctg
    24661 ttgcagtttc agaacaagga aaagggcatg cacggcattt gttacaatta ctgattacgg
    24721 aacaaataaa agattcgctg catgtttttt tagaagtacg tctatctaat gaagcagcaa
    24781 gaaaacttta tgaatcagaa aagtttcgta tattaggtaa acggaaatca tattatcgca
    24841 atccgacgga agatgcgatc attatgagca gaaagttaaa aacggagacg atgaaatgaa
    24901 tgaagaattg attctggcga ttgaatcaag ttgtgatgaa acgagtgtag cggtcgttag
    24961 aaatggaaca gagatcttat ctaacatcgt tgcttctcaa ataaacagtc ataaacgttt
    25021 tggtggcgta gttcctgaag tagctagccg ccatcacgta gaacaaatca ccttatgctt
    25081 ggaagatgca ctggtagaag ctggtgtgtc ggcagaagat ttatcggcag tcgctgtcac
    25141 ttatggacca ggacttgtcg gctcgttgct gattggtatt tctgcagcta aggcttttgc
    25201 ttgggcacac caattgccgc ttattcctgt aaaccatatg gcagggcata tctatgcagc
    25261 ccgtctggtt aaaccattcc agtttccatt gatggcactt cttgttagcg gaggacatac
    25321 agaattagtc tatatgcaag aagatggatc atatgaaatc attggggaga caagagatga
    25381 cgcagcagga gaagcttatg acaaagttgg aagagtatta ggtctttctt acccaagcgg
    25441 aaaagaaatc gatcagctag ctcatcaggg aaaagataat taccattttc cacgagcgat
    25501 gatccatgaa gataattatg atttcagttt tagcggatta aaaagtgcat ttatcaattt
    25561 ggtgcataat gcacaacagc gtggagaaga tctagacaaa aatgatttag cagctagctt
    25621 tcaagcaagt gtgatcgatg tattgattac taaaacactt cgagcttgtc aaaattatcc
    25681 agtcaagcaa ctgattgtag ctggaggtgt agcggccaat caagggttgc gtgaaggatt
    25741 gcaggatgct ttggcaacta aactccctga ggtagaacta gtgattcccc ctcttcgact
    25801 ttgtggagat aatgctgcaa tgattggagc agcagcacat gtggaaatgc aaaaaagaaa
    25861 ttttgctagc tatcagttga atgctgatcc aagcttggtt ttatctgaat aaagaggttg
    25921 tgaaaaatct gccctgcatc aagtaataag aacagcccag gaaaaacggc ttctcatgtt
    25981 tttgacctgg ctgttcttat taccgcgtat gcaagctttt gaacgccgtt taatcaagag
    26041 ttcgtaagcc tgtcgtttaa ctctgattca caaggaacaa tttcaaaaaa cagctcctca
    26101 tgtttatgaa cattatgact tgtgaccgaa gagttgacag gtacacaccg tttaatcgaa
    26161 ataagggctg tgacacgctt ttgtcaaagc cctatttttt acagcttatt catcattatc
    26221 cgttcctctg attgccctca ctgattaatc gtttattgtc gaggaatatc gaataatcta
    26281 ggtcggatga ggacaagacg cttcctctag ttaatctatc agtatttttt gcaaacagtg
    26341 aatattacat aactgaaaca cacatagaaa atctttgagt cttgcccagt gatctaaaac
    26401 tgccggatct ttcagaagtt ttagggagga aaataagcag tgaccctgat aaa
//
LOCUS       DAZKCW010000034        26251 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000034 DAZKCW010000000
VERSION     DAZKCW010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.034"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            236..1876
                     /locus_tag="ACG84Z_001678"
     CDS             236..1876
                     /locus_tag="ACG84Z_001678"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFP9162523.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2030..3352
                     /locus_tag="ACG84Z_001679"
     CDS             2030..3352
                     /locus_tag="ACG84Z_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFP9162524.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3414..3845)
                     /locus_tag="ACG84Z_001680"
     CDS             complement(3414..3845)
                     /locus_tag="ACG84Z_001680"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9162525.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3909..4745)
                     /locus_tag="ACG84Z_001681"
     CDS             complement(3909..4745)
                     /locus_tag="ACG84Z_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFP9162526.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4935..5237)
                     /locus_tag="ACG84Z_001682"
     CDS             complement(4935..5237)
                     /locus_tag="ACG84Z_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFP9162527.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5263..5694)
                     /gene="ruvX"
                     /locus_tag="ACG84Z_001683"
     CDS             complement(5263..5694)
                     /gene="ruvX"
                     /locus_tag="ACG84Z_001683"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFP9162528.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5691..5957)
                     /locus_tag="ACG84Z_001684"
     CDS             complement(5691..5957)
                     /locus_tag="ACG84Z_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFP9162529.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6211..6936)
                     /locus_tag="ACG84Z_001685"
     CDS             complement(6211..6936)
                     /locus_tag="ACG84Z_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFP9162530.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7302..7372)
                     /locus_tag="ACG84Z_001686"
     tRNA            complement(7302..7372)
                     /locus_tag="ACG84Z_001686"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7338..7340),aa:Gly,seq:ccc)
     gene            7489..8241
                     /locus_tag="ACG84Z_001687"
     CDS             7489..8241
                     /locus_tag="ACG84Z_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFP9162531.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8257..8736
                     /locus_tag="ACG84Z_001688"
     CDS             8257..8736
                     /locus_tag="ACG84Z_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFP9162532.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8987..10567)
                     /locus_tag="ACG84Z_001689"
     CDS             complement(8987..10567)
                     /locus_tag="ACG84Z_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFP9162533.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10560..11303)
                     /locus_tag="ACG84Z_001690"
     CDS             complement(10560..11303)
                     /locus_tag="ACG84Z_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162534.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11479..12255)
                     /locus_tag="ACG84Z_001691"
     CDS             complement(11479..12255)
                     /locus_tag="ACG84Z_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFP9162535.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12503..13339)
                     /locus_tag="ACG84Z_001692"
     CDS             complement(12503..13339)
                     /locus_tag="ACG84Z_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFP9162536.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13350..14279)
                     /locus_tag="ACG84Z_001693"
     CDS             complement(13350..14279)
                     /locus_tag="ACG84Z_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFP9162537.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14471..14824
                     /locus_tag="ACG84Z_001694"
     CDS             14471..14824
                     /locus_tag="ACG84Z_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFP9162538.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14898..15554)
                     /locus_tag="ACG84Z_001695"
     CDS             complement(14898..15554)
                     /locus_tag="ACG84Z_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFP9162539.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15780..17714
                     /locus_tag="ACG84Z_001696"
     CDS             15780..17714
                     /locus_tag="ACG84Z_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFP9162540.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17800..19023)
                     /locus_tag="ACG84Z_001697"
     CDS             complement(17800..19023)
                     /locus_tag="ACG84Z_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFP9162541.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19017..20888)
                     /locus_tag="ACG84Z_001698"
     CDS             complement(19017..20888)
                     /locus_tag="ACG84Z_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFP9162542.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(20909..22027)
                     /locus_tag="ACG84Z_001699"
     CDS             complement(20909..22027)
                     /locus_tag="ACG84Z_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFP9162543.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22110..22943)
                     /locus_tag="ACG84Z_001700"
     CDS             complement(22110..22943)
                     /locus_tag="ACG84Z_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162544.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22936..23853)
                     /locus_tag="ACG84Z_001701"
     CDS             complement(22936..23853)
                     /locus_tag="ACG84Z_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162545.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24080..25204)
                     /locus_tag="ACG84Z_001702"
     CDS             complement(24080..25204)
                     /locus_tag="ACG84Z_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFP9162546.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            25387..>26251
                     /locus_tag="ACG84Z_001703"
     CDS             25387..>26251
                     /locus_tag="ACG84Z_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9162547.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKK"
BASE COUNT         8152 a         5205 c         4416 g         8478 t
ORIGIN      
        1 tctatttatc tatctaacat atcctttatt cttctacttt tctttcttta gcatataaga
       61 gatacgcata gtaatcaagc aaggattgtt gatataaaaa gaacaaatac cgctattttg
      121 atttcttttg actctattac tcatataaat aaaatttatt atacctgctc tttttgacta
      181 tatcctcatc tgactcctat acttcgtttg tattaaaact taggaggaat cattcatgct
      241 tacagggcta aacttattaa ataatccttt tctaaataaa ggaacagctt ttacaaaaga
      301 agaacgggca aaatacggaa tcactggtat gcttccaagt actgtccaaa cattggaaca
      361 acaatctgtc caagcttacg gtcaatactt aagcaaacag accgatttgg aaaaacgtat
      421 cttcttaatg aatctattca atacgaaccg gacattgttt tataaattga tgggcgaaca
      481 tttagttgaa ttcatgcctg tcgtttatga tcctgtcgtt gcggattcaa tcgaacaata
      541 caacgaaatt ttcttgaaac cacaagatgc tgtatttctt tcaatcgacg aaccagaaaa
      601 tatcaaagca agtttgaaaa acgcagcaga tggacgcgac attcgtttga tcgttgtgac
      661 agatgcagaa ggaatcttag gtatgggtga ctggggtgtg aacggtgttg acatcgctat
      721 cggtaaattg atggtctaca ctgccgcggc tggtatcaat cctgcacaag tcttgcctgt
      781 atcaatcgac gctggtacta ataacgaaga attattgaat aatccattat acttagggaa
      841 tcgtcatgct cgtgtagaag gcgaaactta ctacgaattc attgatcaat tcgttcaatc
      901 agctactgaa ttattcccag aattgttatt acattgggaa gattttggac gaggaaatgc
      961 tgcaacgatc ttagaaaaat acgaagataa aatcactact ttcaatgatg atatccaagg
     1021 cacaggaatc gttgtactag ctggtgtatt aggtggattg aatatatcag gtgagcaatt
     1081 gaaagatcaa acgatcttga catttggtgc tggtactgct ggtgtaggta tcgcaaacat
     1141 ccttttagat gaaatgatcc gtcaaggtgt acctgaagaa gaagcacgcc aacatttcta
     1201 tcaagtagat aaacagggtt tattgtttga agatacaaaa ggattgactc ctggtcaaat
     1261 cccattcgct cgtaaacgct cagaattcac taatgctgat gaattgacaa acttagaagc
     1321 agttgtaaaa gcaatccatc caacgatcat gatcggtact tctacccaac ctggagcatt
     1381 cactgaagaa atcgtgaaag aaatggcggc tcatacccca cgtccaatca tcatgccttt
     1441 gtctaatcca acaaaattgg cagaagcaaa agcaaaagat ttgattgaat ggacggacgg
     1501 aaaagcttta gttggaacag gtatccctgc tgctgatgtg gaatataacg gtgtaactta
     1561 ccaaatcggt caagcaaata atgcgttgat gtacccaggt ttagggcttg gtttgattgc
     1621 ttcaacagct acacgagtaa atgctgaaat catttctcaa gctagtcgag cattaggcgg
     1681 aatcgttgat gtaacaaaac caggagcagc tatcttgcct ccagtagcaa aaatcactga
     1741 attctctcaa acgattgctg aaactgtcgc aaaatcagtt gttgcacaaa aattgaatcg
     1801 tgaagaaatc acggatatca aagaagctgt tgaatctgct aaatgggttc ctgaatataa
     1861 atctttagaa gattaagatt gttatagtaa aagaacatac agaaactttg tatgacgtct
     1921 aaaaagaaaa aagcgactgc ggcaaaacag cagccagcca actactgctc ttttgccgct
     1981 tctctttggc ttttttcata cgatacagaa taagaaagga tctgtaaaaa tggcacaaaa
     2041 aacaacaacc gcaactgcag ttgaggaaaa gaaaaaagaa gggttttggt caacaaaaat
     2101 taccggcgta agtttgcccc tttatttgat catggtcctt gtcctgatca ttgcaatggc
     2161 tttaggaaaa ttaccgacga atatgattgg cccaatcgct gttttggtca ttttcggtaa
     2221 tttatttcat tttatcggaa caaaaatccc tatagtcaaa agttatttag gtggtggctc
     2281 cgtttttgcg atctttgcct ctgccgcgat tgctacattt gggatcttac ctgagtatgt
     2341 agtaaaatcc acagaaaact ttgtcagcaa tatgggcttt ttagactttt atattgctgc
     2401 cttgattact ggtagcatcc ttggtatgaa ccgtaatcta ttgatgaaag cttctgttcg
     2461 ttttattccc gttgcactta tttcaatggt cgtctccttt tttgccgtag gactcgtagg
     2521 tatgcttatc ggaaatggtt ttgcaaattc cgttttatat atctcattgc ccgcaatggc
     2581 tggtggtgtt ggagccggag ctgtaccttt atcaacgatt tatgcaaatg ttttaggtac
     2641 ggacgcttct tctatcattt cccgcctgat tcctgcgaca gcaatgacaa atgtcctagc
     2701 tatcattggt gcagcgttag ttgctcgtgc gggacaatca atgccaaaat tcaacggtaa
     2761 tggtaaatta atggaaaaag gcgaccttgg cgatggaaaa cctagaaatg taaaaccttc
     2821 cattccacaa ttaggtgtcg gtttgatggt atcattgact ttcttcatct taggacaaat
     2881 ctgtaactat tttgttccta aagtccatgc ttacgcattc atgatcatta tcgttgttat
     2941 ctgtaaaatc gcaaacctat taccagaata ttacgaagat gcagctatca tgttcaacaa
     3001 cttgattgtc aaaaacttga cagcagctgt tcttgccggt atcggtattg cgttattgaa
     3061 tctaaatgta ttggcttctg ctttgacatg gcaatttgtt gtcttatgtt tgacaagtgt
     3121 tatcgcgatt tcagtagttt caggatttgt cggtcgtttg tttggtttat atccaatcga
     3181 atcaactatt actgctggct tatgcaacaa ctcgatgggt ggtacaggaa atgtagctgt
     3241 cttatctgca gctaatcgga tggaacttat tgcttttgct caaatgggca atcggcttgg
     3301 tggtgccatc gttttgatca tctcaggttt cttgatgcaa ttactttctt agtcaaaaaa
     3361 aatacctgat catcaagtat cggcttgatg accaggtatt ttttgataaa aatttacagg
     3421 attttcaaaa atcttttttg cattttatcg gaatgataac cgatgcgttc ataaaatcgg
     3481 tgtgcttcta ctctgtattc tgcagaatta agtcttattg ctgatattcc tcgtcttttc
     3541 gcttcttcta cgccagtcat caaggccttt ccgattcctc ttttttcagc atgtttagac
     3601 acagcaagtg ccataatatt gaacatcgga tcgctgaaaa tcgattcata ggactccgct
     3661 tgtacatagc cagctgcttt tttagaagta ggatcttcat agaccaagaa aaaatttttt
     3721 tctggctcct tcaacagttt cttcatttgt ctcaccgtaa cggttaatgg tacatcatat
     3781 cctaattgtt ccgcattgat ttctcgtagt gcttctgcat ctcctaaacg catttcccgc
     3841 aacatccaaa tcaccagcca atttttattt ttttaaatga atttttttat cacagtatac
     3901 tccttttttc acttaaaaaa agacttttca gtgattttga cttgcttgaa tccagatcct
     3961 tctaatgttt gcaagatgac gaaagcattg taaagattga tcaaaagaac cacgatgaca
     4021 atcgcttgaa aaataaaggt cacttttttt ggagacaaaa ccctgctaaa tcttgctccc
     4081 cacaaacctc caataacagc agcggggata acataaaaca acatagataa atcaaagcgc
     4141 ataaagctac ttgttaaagc aatcgttacc aattttgcca gttgagaaaa gaaaatcgta
     4201 gatagagaat atagtgttgc ttcttttatt ggcaatgcaa acatcagcat caacaaagaa
     4261 acattgactg gtccaccacc aatacctaaa aaactagcta aaaagcccag aaccccccca
     4321 catataaggt accaagtcca tgacgtcaaa tgaaattttg gctgatgatg cttggtgtag
     4381 aagaacgcaa aaaccaaggt caataccgtc aaaaaaattt ggatcagctg cacatgcttc
     4441 tcgttttcaa ataactgtaa aaaaacttcg aatacaatgt tgccgactac tcctccaaca
     4501 acagctccac tagataccca accgacaatc tgccaattca gtgatttccc gcttgatact
     4561 tgtcgcacag tcgaaacaat ggacatcgtg aataccgcaa ctgttgagta aaaagaaatc
     4621 cctgcaacag aatgggcgcc gataagatca agaatcggtt tgatcaacac gcctccaccc
     4681 atcccggaaa tagcgccaac tgtgttcgcc agaacgatca ccacaaaata aatcagacca
     4741 atcatcttgt atttcctttc tcttgtttat atcttttagc gattgttact cttttctttt
     4801 attatacagt aaaagaaaca aacgaggctt cgaaagcttt tctacttttt aaggaaattt
     4861 agtgctaaac gaaaaaaccg ggctctactt ttcagagagt ccagcttttc ttacacctta
     4921 tcgattcttt tgttctattc ttcttccgcc atgaatgtat tgaatacttc ttcgatcata
     4981 tcccattctg cgtctgtttc gatttgttct aactcgcctt ctgttccatc ttcgttttcg
     5041 atgtatgcat aagcttgtaa ttctacatct tcatcttctg aaacaccagc tggatataaa
     5101 agaacatagt tacgtccaaa ttcttcttgt ccgtcaactg ttagcaagat ttcgtataat
     5161 gtttcatttc cttggtcatc caccaatgtg atgtgttcgt gtccttcgtg ttcgtgggaa
     5221 tggttatgtt ctgtcataag attacctctt ttctttttat tattaaaata attgcttacc
     5281 tgagccgtct aaataatttt gtaaaatcat cacagctgct aatttatcga tgactttttt
     5341 tcgtttcgct cttgaagtat ttgcctgctc tactagcata cgttctgcct gaacagtggt
     5401 tagtcgttca tcttgataat caaccggcaa ggagaatagt tctttgatct tctctccata
     5461 tgacatggaa gcttctgccc ttggtccgat ggaattgttc atattcttag gtaatccaac
     5521 tacaaaacgg tctacttcgt actgcgccac taattccttc aaccgatcaa aaccaaactc
     5581 ttcttctgcc tcattgattc gaatgatttc tactccttga gctgtccagc caaagggatc
     5641 gctcacagca acgcctactg tcttagaacc gacatccaag cccattactc tcataaattc
     5701 actccatgat ttgagaggta gtctttgaca attacttcca tgatttcatc gcgttcgtga
     5761 cggcgaatca aatttcgtgc atcacgataa cgaggaatgt aggccgggtc tccagaaagc
     5821 aagtagccga caatctgatt gattggattg tagccttttt cttccaaagc ccgataaaca
     5881 atcgctaatg tttcgctcac ttcttttttg cgactatcgt caaaaccaaa acgtacggtt
     5941 tcatctgtaa aacccatgat tctacacctc tttcccgcaa ggtaattcca gcttaccttc
     6001 tacaccctta ttttactcga agaaagggaa aactacaaac aaatattcca aacttctgaa
     6061 taaattaaga aacacgattt gtctgatttt tccttttttc tgtggctttt tcaaaagccc
     6121 tctttccata aagtatacgc tatatttctt tgaaagtatg tttttacaca attttttcat
     6181 aaagttcata aaaaattcga attgctgcta ctaatttttc gttttcgttg cttgccctgt
     6241 ctcataattg atggtgtagc catcttgaac attgtagata aagacattga attcaatttt
     6301 tttgtcttca atgctttctg cttccaactg cacacctctt gctaccagtt catttccctc
     6361 gaaatgagga gtgacacgat agcgtacatg atgatttgtt tccttgatat atgccgcaat
     6421 atcattttcg tgggcaagca tgtacggagc attcaacgaa cgtgtccctg tcattaagtt
     6481 tttaatgtta ttattttgac cagtcaactg gaaaccaatc aaatggctgc ggttgtataa
     6541 ccattgtccg tcacttaatt tcttttgttt ccaacctgtc ggatcaatat acaaaggttc
     6601 tctcttttca gtaggaaaca agtcttttcc caacatcgca ttggcttgtc ctactctgtt
     6661 caatttgtct atatttgaat agctttccca tgtccctttg gaaagactaa gatcctcttt
     6721 tgtaaactcc ggctgattcc cattgatttc tatttcttga tgttttccat catattctgg
     6781 cacatccgct acttgagaag cttgcggtgt ggaatcaaaa atggttgtaa tttgttggaa
     6841 gatatctgaa tctttttgtg tggtggaaat accgagtgcc cctgcaatca cagcagcgac
     6901 gatccccacg atcgccttgg ttgttttttt gctcatttct ttactccttt actaacagtt
     6961 ccctaaatct taacatatgt tcccctataa ataaatactg gaaagaaata gaaacagtaa
     7021 aaaaataaaa ccagttttta gacggcttaa gaatacaaaa aaagagacgg attcatcgtc
     7081 tctactcaat cacaaaacac tatttacaag gtatttatta tcattcaaaa aatttttctt
     7141 aatactcaaa actaaacggc ttctgtacga cctcttggta aacagtgttc aaaagcttgc
     7201 atctgcggta ataagtccaa ccaagtcaaa aacataagaa gcttttttgc ttgactattc
     7261 ttattacttg atgcagggca gctttttcac agcctctttt aagcgggtga cgggaatcga
     7321 acccgcgaca tcagcttggg aagctgggat tttaccacta aactacaccc gcgatacaaa
     7381 aacagtatac gcctctttca ctccttcctc aagttttttt attctttacg cttccgatat
     7441 gttttgtagt aaaataaaac taatcaatca attattggag aagatgctat gacgggaaaa
     7501 gaattagatc tgttgctgga cacttgttta ctcgctggga aaatcatgat ggaaagcaat
     7561 gcggagatgt atcgggtaga agatacgatg agtcgaattg ctttagcttc tggaaatttc
     7621 cgtttggtca gctatgtcac tcaaaccggt ctctttattg gtcttgatcg tacctcgacc
     7681 atccgaatgg aacaaattac caaccgttcg attaatttag aaaaagtagt aaaagtaaat
     7741 gatctttcac gtaaatatgt tgcttcagag ctaacattag aagaacttta ctgcgaactg
     7801 caagcaatcg accgagaccg ttctttcttt cctgtctggt tgcaaatcgt tagcgcggca
     7861 gtgatcagtg gaacaattat ggtgttattt ggcggaaaga tgaccgattt acctgtgact
     7921 ttagtcattg gaggattggg atacgcagct tatctatata gtttgaaatt ttttagaatc
     7981 aaatttttat cggaattttt atcttcttta ttgattggca tagccgctat ctacagcgta
     8041 cgttttggct taggaagcaa tcaggatcta atcattatcg gatgtgtgat gcctttagtt
     8101 cctggagttc aaattacgaa cgctatccgt gatttgctag ctggacatta tgtctcagga
     8161 gtttctcgcg gaacagaagc gatgatgact gctacgatga tcggttttgc gattgctttt
     8221 attttccagc ttttttatta ggaaaggaac acaagtatgg ggacgatatt tattcagttt
     8281 tcttttagtt ttttagcgac tgcggcattt gccgttatta caaatgtacc taggcgttca
     8341 ttgatttgtt gtggtctttc tggtgctttt ggctggatga tctactggat ctgtgttcaa
     8401 ataggcggat ctgctgcttt tggttcattg cttggttctt taggagtagc attcatcagc
     8461 gatcttttct ctaaacgttt gaaaatgccc gtaacgattt tcaatattcc cgggatggtt
     8521 cctctagtcc ctggtggttt agcttatcaa gcggttcgaa atctcgttac tgaatcctat
     8581 cgagaagcgg ctcattatgc ggtccaagca attatgattg ctggagcaat cgctttaggt
     8641 cttgtattat cagaagtctt taaccataac atccgtaatt tcaaagtaaa gcgtgacgca
     8701 atcatgatga aacgaaaaaa acggcttttt aaataaacga agtgtaacaa agaaaaggtt
     8761 gtgaaagaga cgttcagcct tgagcgatga caaaatatct cacaaacatt gcgacaagta
     8821 accgcaggag caataagaag taattatgag tattaaaaaa agttttgtaa aaatagcttc
     8881 tcacattttt acataaaatt gacttaatac tgagaaactg acttttgaac accctctatc
     8941 tgtaaaaaag gggctgcgac atgatttttg tcacggcccc tcttctttat tcaaattttt
     9001 tccaaaacgt tcgttgataa taaacgatcc atagagcgga aagtattaga actaaaccga
     9061 tcacaggaat attcactaac caaaatggat aaaacaaagc caacattccg tataagacga
     9121 taagaataat actgatgatc aatgaaccca tcatagttgc gactaaaccc aaacttcctg
     9181 aacctctgtt aaataattgg ttaatattgg tccagttcag cagcagcaac cgataatctc
     9241 tagcgaaata acgtagtgac aataagtagc agccgaataa agaaccaaat agcaagctag
     9301 ggataaaaaa caaaggcagc tgaaaagaca gtccgcttaa taatgcgatc ccaccagtta
     9361 aaaaactctg caatatccat ccgaatctga acttttcttt taaatattgg ttcatagaga
     9421 ttggcaaaga acggataaac agaaaatttt cttgatccaa agaaataaga ttgctgataa
     9481 aagaagtctg attaactgtt aagaaagcca atgcgatccc taccaggaaa acaacaccga
     9541 ttaacttatt atctaaatca gttaatttta tttcgcctcc tagggcaaaa gcaagaataa
     9601 aaatgattgg agttaacaag gaagaagaaa gaacttgcat aatcaaatta ggttctttta
     9661 ctaattgagc attgtaacta aataaaagct gatgcacatt ttggttcttt ttatgggttc
     9721 tttttatttt gaactcactg tttgaatcag tcagttgctc tgtaagcttt ggtactatca
     9781 gctgttttac agcaaggaaa aatcccagag ccgtgatagc tagtattccc caacccaata
     9841 aaccttgttg agaaagtggc tgactggcag catcatagaa tggcaataat atcgaaatcg
     9901 gatgccgatc tgttaactca ttttcaatag tccccgtttg atgattcatc cacatgattc
     9961 cagcaaatgc gatcagcatc gagctgccaa gcaagatact agaaactgtt tttctatgtt
    10021 ttttaaacac tgctgttcga gccaaaccaa aaacaatcaa actagccaga caaaaaagaa
    10081 taatcaaaaa tagagaaaac aaaaggattg agataatgat agtaagcaaa atccctagat
    10141 cagctcgcca tccggttaaa ataaacatga ctagaagcgg aaaaacaaaa ggaatgatgg
    10201 tcaaagcaac taccaaaatc tttgctgaaa aaacctgttc ttgtccaaaa ggcagaggca
    10261 aaaatacttg caggtcattt ccttcaaaaa agatattata aatgactgat atactttgag
    10321 ttaaacctaa cataccaaaa agtgccacgt aataagtaaa gaaacctggc aatttaacaa
    10381 agttcatagc aaacatagca aatccgtaaa tcagtaaaaa aatcagccct gaaaaaagat
    10441 tttgagacaa aagatagata gttaatcgct ttcccttttt tcctttctct cttgctttat
    10501 tcgtgagctg tggattaaca tataaaagat taactcgaat taattctaat aattgtcgct
    10561 tatacatacg gtccatctcc tgtcgcttgc cttccagcca ttttcaaata aatcttttct
    10621 agcgtttcat caggtgagcc attcaataat tcactaactg ccccctgata aatcaattca
    10681 cctttcttca aaatagccag tttatcgcat aactgttgtg cggtatccaa tacatgtgta
    10741 gaaaaaatga ctgtttttcc ttttgcggca tgagccttca tcatttcttt caaatcaaat
    10801 gctgcttgag gatcaagtcc ttgcaaaggt tcatccaata cccaaatatc tggatctggc
    10861 agcaacgtgc cgatcaaaat cgttttttga cgcattccat gtgaaaaact tgcgattgtt
    10921 tcattttgat gactatacat atcaaaaagc gctgtcaatt ctgctaaacg cttttctttt
    10981 ttttgtgtgt ctaattcata ggcagctgaa atcaagtccc aatattctcc agccgtcaat
    11041 tgtaaaaaaa tatctgggga atcaggcaca taaccgattt tttgtttgat actcaatcga
    11101 ttttccgtca atttcattcc atctactaaa atcgttcccg atgatggttc aataatacta
    11161 actaaacttt taatcgtagt tgattttccg gcaccattat gtcctaaaaa tccaaaaatt
    11221 tccccttgtc ttatcgagag agacaagtct tttaatgctt gttttttccc gtaactttta
    11281 cttacattga tgaattcaat catttctgta ctccttttgt ttgttattac tttttattgt
    11341 acccttcgtt attggtggag taaatgtcaa aaagagtgca taacaaaaaa ggatagaaac
    11401 gactaggctg ctacttgggt tgttctcttc tacaggaaaa cactcttcta acaggtaaga
    11461 tatgagtctt tgttttcttt aaaatgattc attttctatc ttttcttgca taaaattctt
    11521 tagtttatca atacttctct ttcccatctc tagttgttct ccatttgcaa atgttactat
    11581 ttcgtttact ctgctaatag atgtaatgtt ttcagtatta atgatataag cttttaaatc
    11641 tttacataaa tactcatatt cgagtgattt tttatatttt ttaattgtgc cgtttacgag
    11701 aatctcttca tctttcaata ctaggcctat tttattttta taacctggca tgctcattag
    11761 ataaaggatt tcatcgtaat ggatatagtg atcgctatta ccataacgga cagttgtcca
    11821 cctttttttc gtagcatgtt gaacaggata gttttctttt tctttcaata agtaactttg
    11881 gatgcttttt ttattttttt cataagtgaa ttcttttatc aaataaccac taggcgtaat
    11941 ctttcgatta ataacagtta ttgctttatt cggatgagac gttagataaa caattttaca
    12001 cttttcattc ttttctctaa gcatttcgcc tagttcgata ccgctataat aggcgttcaa
    12061 atcgatgtct aggaaaaaaa tatctgagga atagatttca ttatttttaa tgaattcaac
    12121 aaattgtata acgttcaatc cctgaacgat ctcaaatttc caaggactta ataaaattct
    12181 ggattcttcc aaaatttcta ctagcatttt ttcaaaaacc aaactatcat ccaaaataaa
    12241 tatacgcgtt accataaaaa gtacctccac tcgatatttt actatcaaaa tcatttcata
    12301 caacttttca acatacatgt taggaataaa ttgtaattct cttcacaatc ttttccaaca
    12361 cctttgaaac cgatatcaaa tactttcagg atgctgcttc taaaataaat atcaaacaaa
    12421 tgaatacatc atgcaaaaaa agccagacaa ccgacgtcct tgcgtgtcag ctgtctgagc
    12481 tatgtttatt tattttgttc ttttaaaaag aacgatacac atactgattt ttcggagcag
    12541 agactttctc agcgtttgta acaactacag atgggatttc acgcttgaat ggttgataat
    12601 agtctgattg gatggttcct tctattttat accattcatc atttttaacc gttactcctt
    12661 ccggcatatg cgtcaacaaa ccaaagactc ctgaatctgc cacacaatgg ataatgccga
    12721 atcggaacaa gaagatatct gtattgctat cgttcggtgt ttggtaaaca aatccttcat
    12781 agctgatttt tttgccaatg aattcgctag ggtaattata aattagctcc ataacttcta
    12841 aatagttttc atctgtgatc ttgatagttt gcttatcccc atacttttct ttcaactcat
    12901 tcatttggtc taagtagtct gatttgttga aataaatact ggtatccggc tttaagtatt
    12961 gtgtctgcat ctccggatcc cctactgatt ctttacttac tgggaaatta aatcctttgg
    13021 cttctacgat cgtagtgtcg agactaactg ttggaaacaa cgtccccacg attactggca
    13081 aagctagcag tacataagcg attccacgtt gataaggttt tgacaaccca tggtcatgat
    13141 cgtgctcgtg tgccttttct tctgcttttc cgtttttgac ccacaaatac agctgaacta
    13201 aagccaaaag agcagataaa atcattgaaa gaatagctaa gtagcgataa tggacattga
    13261 tatattgatc gagtttgcca gaaacttgca agtacatcat caattcgaaa tacccagata
    13321 aaatcaaaaa ccgcagcata ttttccctcc taaataaata atgtgaatcc aataacgcta
    13381 agggcaatca gtccgatcag cgataaaata aagcgtcctg taaaatatcg tttcatcatc
    13441 agtagatttt tgatatcgac cattgggcca aagaccaaaa aggcagctac aggtgctgtg
    13501 ccgaacagac ttaacaaaga agatcctata aacgcatctg cttctgagca aagagacatc
    13561 gtaaaggcca ataacagcat gatgataatg gctaaaatct ttgttgagcc gagcgttagc
    13621 ataattctag ttggtaaata agtctgcatc gcagctgcga ttaatccgcc aatgatcaaa
    13681 taacgacctg tatcaaaaaa ttcgtcgatt gaatgtgtca acacatgccc agtttgatgg
    13741 atcagctgat tttttggttc attcttctca ctttgttctt cttcatggac atgatgatgg
    13801 tgattttctg ctactttaga cgtgattttt tctttcaata cagcgtcttt ttgaaaatag
    13861 gcaagccaga caccaatcac aagggcaaca aaaaagctgc ctatcacccg ccagcttgcc
    13921 atctgccaag aattgccaaa tgcgataaaa gtggaaaaaa tcacgattgg attgatgatc
    13981 ggagcagtca gcataaaagc aaacgctgtg tgaactggta cgcctttttt aacaaattga
    14041 tgaacgatcg gtacgatgcc gcattcacat gaaggaaaga aaaatcctaa gatcgaacca
    14101 gtaaaaatag agaagatacg attttcagga agccatctct tcacacgttc tggggtcaaa
    14161 aatacttgta aggcgcctga gataagacag cctaataata cgaaaggtaa tgcttcaata
    14221 acgatcgata agaaaatcgt actcatctgc aaaaccgaat ttggaataaa agaaaacatg
    14281 agtttcctcc tttttatttc tagttcattc gctttgcaaa tatacgcttt tattcaaaaa
    14341 aaacaagttg ctctgtaaat ttttacacaa ctcttatttt ttaccaaagc acttcaattg
    14401 actttttctg ttattcccat taaattaagg tctcatacat atcacttcta tcataaaagg
    14461 gagaataaaa atgaaacaaa ccactaactt gactgaagtt caagacatac tgcaacagtc
    14521 atccgttgcc gtcatttatc tttcgatgcc taattgcagt gtttgtcacg ctgttcgtcc
    14581 acgactagag gaacttctca cacattatga tattccggca cttcatttgg atgcatttga
    14641 aacaccagaa gtagctagta aatttgaagt gctgactgcg ccagttgtcc tgatttttca
    14701 tcaaggaaaa gaagtctttc ggcaagcacg gttcatcgac tttaaaaaaa tccgttatct
    14761 actagatgaa ctgacagcag aagatgattc cctttcttat gaagaaatct tccgaacaaa
    14821 ataatcgttg tccaaacaga aaaaagcgat tgaacaagtg aaagttttgc cttcatttgt
    14881 tcaatcgctt tttattttta ttctgctgta ttttcggaat gcgcatttgc gtcagaatgc
    14941 aagaaataga tcaaggtttg caattcattc gtcaaatcaa cattttggat caatacatct
    15001 gacggagcat tcaatcgagc agcggtaaag ttcaagattc ctttgattcc tgcttccgtt
    15061 aactgattga ctacttcttg tgctctttca gcgggtatcg ttaaaattgc tacttcgatt
    15121 tgttggatct tgatttgttc tgacatatct tccattggat aaacggggat accgtctacg
    15181 atgcgcccaa cgatttcctc attcacatca aaagcacaac tgatacgtat gctattactt
    15241 tgatggaatt tgtattttag taaagcactt cccaagttcc ctacaccgat cagcgcaaca
    15301 tttgtcaatt gatcgtcgtt taatgtcttt gcaaaaaagt gcataagatc ttctacatca
    15361 taaccatacc cacgttttcc taattcgcca aaataagaaa aatctcgacg gatcgttgca
    15421 ctatctactt gaacggcttc acttaattca gttgaagaca cttttttctt tccagcatta
    15481 tttaaaatcc ttaaatagcg ataatacaaa ggcagtcttt tagctgtcgc ctttggaata
    15541 atatgatctt tcacgaaatg acctccacgt attgtctaat tacatctttg atttctccat
    15601 catagcagta tttataggaa aaaatcaatt ccattgctca gatattgtga aattttattc
    15661 tttattcatt tatttatcat ttctgcaaat ctcgcagtat aatggaattt atggtagact
    15721 actaattgaa aaatagtttt ttatttgagg agaattcaca aagtagaaaa gaggattcca
    15781 tgatattatt acaagccaat cagattgctc gccattttgg tgcagaagtc ttatttgaaa
    15841 acatacattt agaaatcagt acaggcgctc gtgtcgcttt agttggcaga aatggcgctg
    15901 gaaaatcgac tttattaaag atcattgctg gaattgaagc acctgatgaa ggaaagatcg
    15961 ctaaaaataa aacagcgact ctcggatacc tcgctcagga cacaggactt gattccaatg
    16021 aaacagtttg gaacgagatg ctgaaagctt ttgaacaagt tagacaaatg gaagagcgga
    16081 tgcgcgagct agagattttc attagcgaag gtacgccaga cacacctgct tatagttctt
    16141 atttaaaaga atacgaccgg ctgcaacacg atttttcaga tcgaaacggc tatggttatg
    16201 aaaatgaaat tcgttccgta ttgcatgggt ttaaattcga ttcttcattt tatgatcaga
    16261 aaatcgatac tttatcaggc ggacagcgca cacgtttagc tttagctcgc atgcttttgc
    16321 aacaccctga cattttgatt ctagacgaac caacgaacca tttagatatc gagacacttt
    16381 cctggcttga gaattatctg caaagctata ctggtgcatt attgattgtt tcccatgacc
    16441 gttatttttt agataaagta gtcaatgaag tctatgaatt aagcagaaga aaaatgcgcc
    16501 attacaaagg taactattcg aaatatctag atttgaaagc agaacagtta gcaagtgaat
    16561 ggaaggctta tgaaaagcag caaacagaaa tccataaatt agaagacttc gttgctcgga
    16621 accttgttcg cgcctctacc acaaaacgag cgcaaagccg cagaaagaca ttagaaaaaa
    16681 tggaccggct ggatcgtcct caaggggatg aaaaacaagc aaactttcta ttcagtatag
    16741 aaaagccttc tggaaatgta gtcttgcaaa tcgaagatgc cgctatcgga tatgataatg
    16801 tcaccttatc tgaaccaatc aatctagata tccgtcgtca agaagcgatt gctctagtag
    16861 gtccgaatgg tatcgggaaa tcgacgttgc tgaaatcaat cattcaccag atccctttta
    16921 tccgtggaaa agaaacgcta gggacaaatg tcaccatcgg ctattacgat caaggtcaag
    16981 ctgatctgca tacaaacaag acgatcctag cagaattgtg ggatgagcat cctaccactc
    17041 cagaaaaaga gatccgaagt gctttaggtg ctttcttatt ttctggcgaa gatgtagaaa
    17101 aaccaatccc tctgctaagt ggcggtgaaa aagcacgggt tgctttagcc aagttagcga
    17161 tgaacaaaga aaattttttg attttggatg aaccaacaaa ccatttagat attgacaaca
    17221 aagaagtatt agaaaatgca ttgatcgatt atgacggcac actgcttttt gtttcccatg
    17281 accgatattt catcaatcgg atcgcgacaa aagtcgtcga actctctgaa aatggcagca
    17341 aagtctatct aggagactat gattattatt tagagaaaaa gcaggaagaa gaagaaatcg
    17401 ccgaattgtt ggcacaagat gagccagaat ctgctcctgc tcccacgaac aaatctgatt
    17461 attaccaaag caaagaacag caaaagctta tccgtagcct tcaacgaaaa attactcagg
    17521 ttgaagaaga aatggcgcgg atcgatgaat ggatcgatca gttggaacaa gaaatggtcg
    17581 cgccagaaaa cctggaagat cacgtaaaac tcaatgagct gaaccaagat ttagaagctg
    17641 ctagacaaga tcaagaaaca aaattgacgg aatgggaaga actaagcttg gaattagaag
    17701 aatatgaaaa ttaacgaaaa aaccaaaaca gaaaccattc atgctgtttt ggtttttctt
    17761 tttttatttt atcaaacaaa aattccatat ttaccttttt caccaataag aagaccaatt
    17821 actagtcatt ctcactaaag cttctaaata atagtaatca ccccaaatac aaggtgtatt
    17881 taccccatta tttttgggct tattataaac agactgtgtt aaaaagccat cttcttcttc
    17941 cgttgtagca tatctttctt tcaattgtcg cataattttc caaacagcag actggtataa
    18001 gttcttttct gttttgtcta atagacctga ttctattaat tctaataatc cacaaaccat
    18061 gatcaccata ctagatgtat ctttttcttc tctgctagaa tcatcaaaga tcaaatccca
    18121 ataacaaatg gtatcttctg gcaaccgatt cataaaataa ttggctaata ttttgcttaa
    18181 atcaaaatat ttttgttctt tcaaataacg ataacttaat gcaaaaccgt aaatccccca
    18241 tgcttggcct ctagcccaac aggaattatc actataacct tgatgcgtac ttccatatct
    18301 tggttttcca tctttgacat ccatataaaa tgtatgataa gttgaaccat cttctcttac
    18361 taaataatct gctgcatttt gaatatgagc ctgagcagct tttttatatt tttgatttcc
    18421 agtttcttca ctcgcccaat acaataatgg aagattcatg caacaatcca tgatcattct
    18481 accttgttgt gaaggatcac taggatctcc ccaagcttgt ataactcctg ccttctccca
    18541 aaaacgctga agtaatgttt ctgcagcatc aattgaagct tccttcattt ttcgatttcc
    18601 cgttatttta taatctgcta cggttgataa agaatacaaa aaaccaagat cgtgatgatt
    18661 agtgataatt tgacagtcaa tcctgtggat aaaatctata tctgcttttt cagctgtttg
    18721 ttgaaataaa ggatcacccg tcttctcaaa taacaaccaa ttaattcctg tccaaaatcc
    18781 ttctgtccaa ccaatattgt ctcttaatgg ataacgtcct tttataggac actcgcttgg
    18841 gaattgatac tgactgttac tgatacgttt gattaacctc tccgtgtgtc tgcgacaacg
    18901 ctcgatctca ttattccatt ctttttccat taattcttta taacattcat ttatccattt
    18961 ttctggatgt attatctctt caaacatcac tttatcaagc atttccccac cagcctttag
    19021 cataatttta gtcttttttt attgttttta ttttggatag ttagcccggt tgtcccatca
    19081 aaatcaattt tgggacgatt gttccatact tctaaactat aatcccgatc ttgatgagca
    19141 accactcctg ttccgagcca atgggttcct tttccaaatg taccctctaa tccaggaata
    19201 aaagtgtttt cccatgtcat caagtttgta ttgggcaaac ccataatagc tgtggatttt
    19261 cgtttaatag tatcgtcact taaacagata atacctgaaa agccagcttc actcacccta
    19321 tagttttcct tgtcttcttc tatgattatt ccttctttct caggagaaca ttcaatagca
    19381 aaccctgtct catatagaac atattctgta tctaattcta ctttgtgtac gcgaatctgc
    19441 cagccttcaa aaggaataag ccaagttctg atttttgcct gtaaagtagg ttcccatgta
    19501 gaggcaagta cctctttctt acatacaatg tctcgtacat tatttcgaac gatgaactgt
    19561 ccataggttt tgatgctctc attcttaaaa ctggtcgtga tatatgtgtc cgctcgctga
    19621 atccctagca ttgaatccat tgccatttct gctttcaatt gattcgctcg cggtatcgaa
    19681 aaaccaaatt gactagaata agcaaatttt aaatattttt cattggtcaa tgtatggaaa
    19741 tttggcccta attgtcccgc attcaaaaaa aatgtatgtc cattatcatg ttgtatgagc
    19801 aaattggctt ctgaaagaag tttagttcct tcacgaatag gcataggcat ttctttagcc
    19861 gtccaatact catggtcttc aggtagcgcc aacaataaaa aaatcttatt cagccataat
    19921 ggagataacg tactattata gggttcagtc aatgtcaatt gagggtaggt ataaccaata
    19981 ttcaggatac ctttttcatc aaatatttct ttttgcatcc accatcttat attccgattg
    20041 actaacccct tgatttcacc taatttaaaa ggcaaaagat cggcccacaa catagctgac
    20101 caaaagcttg aaactgcaaa acgataaatc atgcttcgac caaaaggcac atttgcacca
    20161 tcttccgcaa aaaaatgaat atagtctcta gaaaaatcaa tagctcggtt cttatatatc
    20221 tggctaatgg gcttttctgg ttctagtacg ctataaatca aaccataata atgaaatgca
    20281 aaaggattat aataatcttg gcgacctctt gaactgtctc gataccagcc attttgaaga
    20341 taacaatttt ctatattatc aaatgcttct ttcagtgctg attctttaac tggataacca
    20401 aatttttgga taattgttcc gacaattatc ttaaaaaatt gccaattacc atctgcacat
    20461 tcatattcaa aaatttgcga gaaccaatga ataatctggc ttttttctcc tgtatctaat
    20521 tttttccata ataattgttc atgatgatat aacgctaata acattgcggg catttctacc
    20581 atacgctggt ctctttcatg tatttctccc caataatcgg gatgggaagg atctgttcca
    20641 gcttttattc ctgatagaat taatttcaac catcgttcat ctaattggtc aattgcgggc
    20701 cccgctcccc ataaaacccg agagaatcct tccattcctg caattttatt tccatatcct
    20761 accccttgat gtatataatc aatttgtgcg ccacttgctc gataaaacgg ctggagtggt
    20821 tgatttatct ttttaaataa gtcaaagtaa tcctgtctgg tccttaatag tggtactgga
    20881 tgtttcattg tattttctcc tctttttact accaaatagc taattccgac tgttctaatc
    20941 gaagtaagcc ttcaataaaa aaataatcag aatagatcag tggcacatta taagtcagtt
    21001 ctctatggta tgcttctgct ccgcctccaa tgatcccatc ttcatccata ttccaatttg
    21061 catagtgctt ttctgtcttt tggagtatat tgatagcagc ttcatgatac atttttgatc
    21121 gtacagagga aacatatcct gctaattcca gaagaccgca tgcagcgcat actccagcac
    21181 tggtatcaat attcgaatct tttacagcaa aatcaatgag aggaatataa ccagtttttt
    21241 cgattttctg aataaaattt actgctatct tttctgctat agctagatag tacggatttt
    21301 ttgtgtaacg ataacttaac gcgaatccat ataaagccca tgcatttcct ctgctccaac
    21361 aagaattctc attgtatcct tgcccgccaa gtaaccgaat atatttccct gattctgcat
    21421 caaattctgc gatatgcccg gttgatccat ctttcctcac tagatactta gctgttgtat
    21481 ctgcatgctg ccgagcaatt ttagagaacc tcggatcacc agtttccctc gaagcccaat
    21541 acagtaatgg taaattcatc atactatcaa taatcatcca accaggttta tggtcattcc
    21601 atgctactaa atagttccct gaaatattat agcgtccagc aagtaccgta gctgcatgta
    21661 accctagttg tcgactatgt ttgttttgag actgttgata atgtgcaata gccgatggta
    21721 agaataaaaa acctacatca tgatgaacgt ctgaaaaatg gtacagggca gattctaata
    21781 attgttcttg ttgtattgct gcctctttga acttttctcg ttttgtcttg tgaaagagct
    21841 gccataaaat accactccaa aaaccattgg tccaccagtc gattcctctg tcctttatta
    21901 cgtctgtata ttttccgttg taagaaatat atggaatttt attccccatt ctgtctaatt
    21961 ccgcatctat cttttcagaa gctacattca aaatttttct tgaccattcc ttcgtctgtt
    22021 cattcatgga tatcccgcca ttcttttaat ttttatgaat gtggagttgc tcctagaacg
    22081 aactagatgg ttaacattcg ttattttttt tacttatttg cagctccaat gtcattctcc
    22141 ttaaatttag actgcgccca cacataaatc aagaccattg ggatcactga agttgctaaa
    22201 attagcataa ttgcgccata attaattggc tcacctgtac tagaaaccgt catatttttg
    22261 ataattaagg gaaccgtata tttatcttta tctgaaagca tgactaatgg aaatagatat
    22321 tgattccaac ttcccataaa gataagtaaa ccactagtaa taatcgtagg tgataaaatc
    22381 ggtacagcga ttttcgtaaa aatcacccac tcattggcac catcgattct ggcagcctcc
    22441 atcagtgctg taggaaattg actgctatat tgtcgcatca taaacactga agttgtactg
    22501 gcaatcgaag ggatgatcac acctgcataa gtattcgata atcctaaacg actcataatg
    22561 taaaataaag gaatcaatgt ggtaaaaaaa ggcaccatcc tagatagcat aactgtattg
    22621 aacaacagtt tattccccat aaaacgatac tttgctaatg cataacccgc cattgtagaa
    22681 ctggctgtag ctgaaactgt actgattaca gcaataacaa tcgaattcca aataatcaag
    22741 ggataattat atctcgccat gatggcttgc cagtttttta atagcatatc cccaaacttg
    22801 aaattgattc cgccacttaa aatttcttga ttactttgcg ttgaagctac aatcatatat
    22861 aaatatggca tcaaaaatat taaggcacca aacacaataa tgacgtacgt aaaaattctg
    22921 ctttgtatct tttgtttagt catttttatc acctccgaat ttaaattgaa tagccgataa
    22981 tataacagat acaaacacca tcgtccaggc aatagcagag gcttttccaa aatcaaccat
    23041 ttcaaaactt gttttatata aattgactcc tacgaccaaa gctgaatttt ctggtccatt
    23101 ggaagtccca aagaatatat ttgggatatt gaaattaccc aagccattga tagtggctaa
    23161 aactgtggcc attaaaatga ttggctttag catggggatc gttaataaaa agaattgccg
    23221 aaatttcgat gctccatcta tttcagcact ttcgtatatc tctttagaaa tcccttgaag
    23281 accagctaaa aataaaatag tgttatatcc tacactaagc caaatcatcg tgatgatcat
    23341 tgatattcgt atccaaaaag gatttgttaa ccactgtaca ccgttaattc ctagcgcatt
    23401 caaaaatcca ttgaataacc cagtcggatt gaaaaaagtc atgaatacgg aagctacagc
    23461 caccgttgat gtaatggttg gaatataata gacagttcta aaaaatcctt ttccttttaa
    23521 ctgtgctgaa ttcaataaaa cagcaaagta aatagctaat agcatcgtta ttggaattga
    23581 tcctgccatg ataatcaaaa cattcgtgta agatttaata aacaatggat ctcggaagat
    23641 agctagataa ttgtcaaatc caacaaattc aaatgagtag ccaattttca taaaactaaa
    23701 agcaaacgag ataatgatgg gaatcaaaat cgtcacaata aagaaaataa caaaaggtgt
    23761 gaccaatcca taagcacttt ttttatgaga cgtatctgtt gcttttttct tgctgttctt
    23821 tattgtcttg cttggtaacg aagattgcat catcgttaag tcctcctaat attttttaat
    23881 caccagttaa ttttacgccg tacttatgag caaaattttc tgcttctttt agatatgaat
    23941 tttcaaaatc acctgtttgc caatagttat atgcagcggt agtcaaataa gacgtagcat
    24001 ctgaataagt ggctggtaaa acagtatttg atgtattttc attgatttta ttcaatagtt
    24061 catagtattt ttgtcctcct tagtagtcaa actttttctc agctgcttct gtttgatagg
    24121 ccaatgagtt agatgtagcc acgcccagct ccagtgcgtt ggctaagcat tcttcatctg
    24181 tcagcataaa tgtaagaaat tgttgtgcca cttgtggatt tttggcatct ttagggacat
    24241 aaaaacttga tcctcctgat actgcacctt ttcctggatt ttcttttgaa aaaggaatca
    24301 gtggagccat gcgccatttg tcagatgcat caggaaaatt caaagacata ttcgtagcat
    24361 accagccgcc agcaacaaac attgcagatt cttgaaatgc tttctcagca tcttgtgcac
    24421 cgtagaaatg tacaatatct gagtcgatca tttctttgat taactttgca gcatgtttcg
    24481 cttctttagt attcagacgg atatttcctt cttcatcaag caaagattga ttctgctggg
    24541 ctagcatgtt gataaacaat tcttggtccc cagattctgg caaggcaatt ccaaaactac
    24601 cagttttttc ttttaatgct tttgccacct ggatatattc ttcccaagaa ctgatttctt
    24661 caaaatctac acctatttca gcaaattttt ttggttgata ataacaaagt gctggggtaa
    24721 aatcactagc ccaaggaata atcgtttcat tactcgtttg ttgacgcaaa atattcaatt
    24781 tttgatcata aaactgatcg ccatatttgt cataaaatcc atattcatca gcactataaa
    24841 aagcatcttg aaatttttcc agcacacctg ctgctgaagt gtctgccatg gagataatat
    24901 ccggcatatc ttcgtgtgtt accaattttg gggtgatcat ttgtactgtt gctgttcccg
    24961 aagctacatt cacaattttt aagtcaatat ttgctccagt tttgcggtta tagatttttg
    25021 cagcattttc aacatagttt gtcagtttgc cgtttgcgac atatacttct aatgtagtgg
    25081 ctttttttat cattggatct gcgatgtttg ctgttacttc ttcgttagtt tttccacatg
    25141 cacttaagct gaataatagg gtaatgttta gcaaagctat caccaatttg tatctttttt
    25201 tcatgtctat cccttctttc ttttcaagtt cttatataaa acgctttcac ttatgtatat
    25261 taacggaatt agtaacacaa atatttatat aaaaaaatat tttacttgtc gttttggctt
    25321 ttcatttttg ttataatagt cattaattat aaatagaaag ctttttatat aaaaagagaa
    25381 aggaaagtgg ttcttttgtt aacaaacaac caatcctcca atcttgtcaa aaaaacacta
    25441 acctattcca tagataccca tcttcattta tctgctgctc cctattttcg actactaata
    25501 aatgaaagcg ctaatttata tgctgaattt gcacataaat ctatagaact agataatcct
    25561 tcccttttat tcattgataa acagcaagaa gtccaaatct tttctactca aaaggaaaca
    25621 caaactttta tcattatcca gttttatttt gatgagcaat tattagcaca tattacggga
    25681 caatcttttt ctatagatca agaaataaca tctatcatta cttttctgaa aaatgaacag
    25741 ttcaaaattg attatctaaa acatagtaag ccagctattt cctatgatca ggaaatcaat
    25801 tcttttttca tactatgcca acagatgagc attcatttgc tttccttatt agttacttat
    25861 tgtctgcaaa aaattcaatt gtcttcctta ccaaggcatt atcaacagga acttgcttta
    25921 ttgacaatac cttcaaatga gaaagtcatt cctaaaaaaa agcatattct ttattcagat
    25981 gaattagttg atccaatcat acgatattta gaagaacatc tttcagaaaa ttttttgctt
    26041 gaacaattag cccaaatttt ttttatcagt ccagccagct taaaaaaaca ttttagaaaa
    26101 gtgaatggaa aaagtgttat tagctatttt aaagaactaa aaatggaaaa agcaaaacgt
    26161 ctcgtgctag aaaatgaatt aacctataca gaaattgcag atatattagg atttcattcg
    26221 atccatcatt tttcttcagc ttttaaaaaa t
//
LOCUS       DAZKCW010000035        26056 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000035 DAZKCW010000000
VERSION     DAZKCW010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.035"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(718..3867)
                     /locus_tag="ACG84Z_001704"
     CDS             complement(718..3867)
                     /locus_tag="ACG84Z_001704"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HFP9162548.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYAQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3881..5125)
                     /locus_tag="ACG84Z_001705"
     CDS             complement(3881..5125)
                     /locus_tag="ACG84Z_001705"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFP9162549.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5118..6710)
                     /locus_tag="ACG84Z_001706"
     CDS             complement(5118..6710)
                     /locus_tag="ACG84Z_001706"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFP9162550.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7220..7945)
                     /locus_tag="ACG84Z_001707"
     CDS             complement(7220..7945)
                     /locus_tag="ACG84Z_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162551.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8099..8425)
                     /locus_tag="ACG84Z_001708"
     CDS             complement(8099..8425)
                     /locus_tag="ACG84Z_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162552.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8462..8827)
                     /locus_tag="ACG84Z_001709"
     CDS             complement(8462..8827)
                     /locus_tag="ACG84Z_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFP9162553.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(8864..9079)
                     /locus_tag="ACG84Z_001710"
     CDS             complement(8864..9079)
                     /locus_tag="ACG84Z_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9162554.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9208..9543
                     /locus_tag="ACG84Z_001711"
     CDS             9208..9543
                     /locus_tag="ACG84Z_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9162555.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9619..11616)
                     /locus_tag="ACG84Z_001712"
     CDS             complement(9619..11616)
                     /locus_tag="ACG84Z_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162556.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11714..11989)
                     /locus_tag="ACG84Z_001713"
     CDS             complement(11714..11989)
                     /locus_tag="ACG84Z_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162557.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12221..12955
                     /locus_tag="ACG84Z_001714"
     CDS             12221..12955
                     /locus_tag="ACG84Z_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9162558.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12994..14136
                     /locus_tag="ACG84Z_001715"
     CDS             12994..14136
                     /locus_tag="ACG84Z_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9162559.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(14764..15249)
                     /locus_tag="ACG84Z_001716"
     CDS             complement(14764..15249)
                     /locus_tag="ACG84Z_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HFP9162560.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(15251..16687)
                     /locus_tag="ACG84Z_001717"
     CDS             complement(15251..16687)
                     /locus_tag="ACG84Z_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFP9162561.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPH
                     YCIMRKILKENFVDSEDFFDQERYNYELTKRRLQINDLSRFSINVVEVDDYSEITDIL
                     KSIRKKYLRKTIFISGSAVDYTPFTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGN
                     SIVSGVLKQRRNLRKNNIQDVLSLRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLE
                     SGEIVTADGMIEEFELSVQNENIVVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQ
                     ALEKLDTEGEVDKKVEQIVSLINSIQED"
     gene            complement(16720..17571)
                     /locus_tag="ACG84Z_001718"
     CDS             complement(16720..17571)
                     /locus_tag="ACG84Z_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HFP9162562.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            complement(17727..17972)
                     /locus_tag="ACG84Z_001719"
     CDS             complement(17727..17972)
                     /locus_tag="ACG84Z_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9162563.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            18077..18850
                     /locus_tag="ACG84Z_001720"
     CDS             18077..18850
                     /locus_tag="ACG84Z_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162564.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            complement(18903..19217)
                     /locus_tag="ACG84Z_001721"
     CDS             complement(18903..19217)
                     /locus_tag="ACG84Z_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162565.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(20736..20954)
                     /locus_tag="ACG84Z_001722"
     CDS             complement(20736..20954)
                     /locus_tag="ACG84Z_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162566.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            complement(20969..23596)
                     /locus_tag="ACG84Z_001723"
     CDS             complement(20969..23596)
                     /locus_tag="ACG84Z_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFP9162567.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            complement(23583..23801)
                     /locus_tag="ACG84Z_001724"
     CDS             complement(23583..23801)
                     /locus_tag="ACG84Z_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162568.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            complement(23798..24673)
                     /locus_tag="ACG84Z_001725"
     CDS             complement(23798..24673)
                     /locus_tag="ACG84Z_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162569.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            complement(24938..25237)
                     /locus_tag="ACG84Z_001726"
     CDS             complement(24938..25237)
                     /locus_tag="ACG84Z_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162570.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            25439..>26056
                     /locus_tag="ACG84Z_001727"
     CDS             25439..>26056
                     /locus_tag="ACG84Z_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162571.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLA"
BASE COUNT         8084 a         4926 c         3662 g         9384 t
ORIGIN      
        1 ggactaatac aggtagtcct cttttttgtt attttgatat tctaaatcat tttttattgg
       61 attattccct tgttcgatat agacccaaat tgatctatca ataattatca aactgagtca
      121 tatagagaca aaaatttcaa aaatgacctg ttaaatggtc atcgaatatc atttaaaatc
      181 aatacgacgg agtcagacac ggagtcaaaa caagcccgct gagagtaaaa aatatataca
      241 gtcccatagg taaagtgcca caggactgta tattttttta tttgagatta cctgaaatga
      301 ttccatttac tttttatctc attttttcct actagttagt atcaaatact ctcctatttt
      361 ctcaataaac tattttgggt tacatggtat ctgaaacagc taaaaccttg tcattacagc
      421 aaaaaatcac tttatctccg tttcatttca gatacatttc acttaagcgg attccaaaaa
      481 aacaaaagaa aaaggaaccc ctagttagcc tatgcttttt attggttcct ctcaaaacac
      541 ggtcatataa caacggggtg gggtaaatga atgaaaaagg tggaggaaac attattcaat
      601 agctgtctta aatacttcgt tataaaatgt gaacaaataa aagacatcta tccctatttt
      661 ctacacttcc actttactac catctttgaa tcgtacaatt ttcttaactc ttctcgttta
      721 cctcaattca ttttcaagtg gaatcagctc atcatctaac attttacgcc atgctcgctt
      781 catttcttgt gcgtatttaa atggcttcgc ttctggatgg ttggctttat atccttcgta
      841 atccttactg ttgataattg ctttcatatt aggaattgga tcttcacctg gcatatattg
      901 cagattagaa gcatgtaatt ctttctcaga aacaaaccac tcattggaaa agacatgaat
      961 caaatcatca ctcgcttgtg taaaatagcg acgtttaatg acaaagatat cttcattact
     1021 atctaaagtc cccacatcaa acgcatttaa aatttgtcgg taaacttctt tgactccttc
     1081 tgttttattc aatttagcca aagctttttc aatttcttct cgtgcatctg aactattcgc
     1141 cgcataagtt cctagtaatt gatcaatata agtagaatca atatcataca acttcgtggt
     1201 attttcacta taaaattcga tcgtggaaaa atcttctccc tctttttctg gttcttcctc
     1261 tattaatgaa cccttcacgg tctcgtacac gccaatttgt tcttccaaaa gttgaatttg
     1321 attgttcaag gttgaagatt tcaccatgtc atcattgtaa tcgtcataag tcactaacga
     1381 ttcataagca cgattcaatt cttggaatgc tttgacgtac tcgatacgga tttcaagtgg
     1441 cgtatgttca tcaatggatt ccatggatga aacctctttt aacttaccat atgcttgctt
     1501 gaatcttttt ttggattcct gataacttgg ataaatcaaa cccgattctt cttttgcttc
     1561 tgaatacagt tttgtcgcat cctcgacatt cttctccatt gtggctggct ttcggaaagt
     1621 aacaattagt ccttttgttt tttctggata cgtacggttc gtacgtgaaa aagcttggat
     1681 caatcctgca tactctagat tacgatccac aaatagggtt tgaatcgtag gtgcgtcaaa
     1741 acctgtcaat agacgatcca ctacgatcac taaatcaatt tgtttcccaa attgtttgaa
     1801 ttccgctctt tttcgtgcca aacgattatt gatgtctccg ttataacgct caatgtctgc
     1861 taatgaccag gaagtatcat aatactgatt atattcctca ataatttttt gcatttcttc
     1921 ttgttggaca cttgaatctc ggctgttttc ttctaatgaa taggtaatag cgattcgtgg
     1981 aaaatcagga tcctccatcg ttcttccttc acgaatgggc tgattaggaa actcttttgt
     2041 taaccagtca ggttctttcg tcatttcttt gatcgctcga taatactttt tggccatgtc
     2101 aatggaactc gtggttaaga tcgcagactt cgttggacgg ccatttcgaa aatcaaattt
     2161 tgtataggca ttgtctggac ggaacatttt atgaatgact ttttggatat gttcatctgc
     2221 ttcaaaaaca gtagggtcca aataactttc ttttttgaca ggctccattt gatcaatcat
     2281 acgattgatc tgttccggtg aatactctgc atatgtttct acttctttta atttccgata
     2341 gattttattc tctaatgaag tcggctccac ggtgttttca tgctctactt gaaatcctaa
     2401 aaccgagcca tcttctaatg cattcttgat ggtataggta tgcaagacct ctccatactg
     2461 atcatgggtc gtacgtgcca attgcccttt ggcttgtttc cgattctcag ggaaaatcgg
     2521 tgtacctgta aagccaaacc aagtggattt cggaaacatt tttttgattt cttccatatt
     2581 ttcagcactt aacgctcgat gacactcatc tactacaaac acgatatgtt gccccattaa
     2641 tttttggaag cgattggttc cttttttctc ttcttgtttt tttgcatatt tcaacgccgc
     2701 atctagcttt tgacgggttg taataatcac aacatttgca ttggcatctg ccaacagagt
     2761 ttcacttaac tctttggcac ttcctgttcc cacgatcaag ctattcgctt tggcgttccc
     2821 ggaagaaatc ccagtattaa attccgaagc aaatttcgta aactctgtgg tggtttgatt
     2881 atctaaatct ttgcggtcca ctaacatgat cgtccgatcg atccccgatt ttcgtgctaa
     2941 aagcttagta gatacaaaac tagtcaacgt ttttcctgaa ccagtcgcat gccacacata
     3001 tcctgattga tgtttatttg cagcaataaa caaggcttga atcgcatgta cttgataagg
     3061 atgtaacacc atgaggattt tattgtcttg atcttcactg acaatcgtat aatccgcaat
     3121 caagcgatga gcatccggga tatttagcac ttgtttgcaa aactcatata agttttctac
     3181 ctttttatta tctttcgttc gccaactaaa taaaaactta ggatgcaaat cctttggtaa
     3241 ggcatttgca aaataccgag tggtttgttc attggaaacc acaaacaact gtaaggtcga
     3301 aaagatattg ttccgaaaca taccttcttc tgcatatttt ttgatttggt taaacgcctg
     3361 ataaaaacta tcttttgcgg ttacttgttt cagctcgatt tggacaatcg gtaatccatt
     3421 gatcagtaag gtgacgtcaa aacgtcgatc ccgtgcttct atgttacttc cacgttttgc
     3481 aatttgatgg accacttcat aggtagagat tcctccacca atgtcttgat tagaataaag
     3541 aatgagcgag acagaaccca gttgcggatc ttcccgttca atcgtgatcc gagccattcc
     3601 attttcacct tttaaccatt tcgcagcatc aaagggggtt ttcgttcgta gtaacaattc
     3661 tgttttgatc gtttcaaatt ctttatcggt caaaggaaaa tcattcagtt ctgcttgatt
     3721 atttgagatg attttttggc gtaaattgac ccaaagatct tcttctgatt ttagatcggg
     3781 acgatacgtc cactgattat gcccttcccc caatacacgg atcaactgtt cttcgacttc
     3841 cgcttcctca cggtgactaa ttttcattta tcttccctcc ctaaacaaac atcttttgta
     3901 agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga gcgatcgtgt
     3961 cgtcgagttg tttgaagaaa gcgccgattt tttgttgttc ctctttattc ctagtaaaag
     4021 gaaacttgat attagcgaaa ttctcataga ataagtattc tcgtacgctt ccttcagtgt
     4081 tgcgcttgac ctctttgata aatgttggtg acttgataaa ctgaagtatg aactcattat
     4141 ctaagtcctc gctcattttc acaactacat aaagagagct aacaatgacc gtcataccaa
     4201 gattgttaaa tgcaattgat cctacgttta ctcttgctgg attataggcg aattcatttg
     4261 gttcaacgaa tttataattt gttttttcta aatcatccaa cctactacca tcaaactgtt
     4321 ctgtttgaga aattaaacct gctttattac ttaccgaata ggcagggaag tctaaatctt
     4381 tcgtgttctt ttttccagtc ttcttactaa actctttgaa cttacgctgt tcccaatctt
     4441 ccgtaaatcc aggaaaccga atttctggca cttttgctcc gtttttaggg aacatttttt
     4501 gtaagaatcc ttttttcgtt tcctttaata aatctagctt acgttgttga agagcgatag
     4561 tgtcgtccag ttgtttgaag aagttcccaa ttttcttttg ttcttctaat attggaaatt
     4621 gtactatcca ttttttcact tctgacattg gtacgagatt tgtaattgct gaacctggat
     4681 tagctcctgt gagttttctt tgcataaaat ctgcacgaat aaattgaata aaatattctg
     4741 aatctgtgat ttctttattt attctaagtc taatcaaagc ctgattgaat acacccggtt
     4801 ttatttgctt tggtactctt gaaattctcc caattgttcc agcgccactc atgataaaat
     4861 cgcctggttc taatttaaat ttgattaatt cattatattt tttttcagta attttatatc
     4921 ttgtttcgta attatcataa atagcatttt gttgttcata gacaacaaaa ttgctattag
     4981 atacaaagaa ttctttcttt aaggcactcc caaatggtcc cctccttact ccatcttttt
     5041 tatcaagtaa gcattcaaac ttacgctgtt cccaagcttc cgtaaatcct gggaaacgaa
     5101 tttctggttg tatatcatta ctcatgtttg aacacctcca gcgcaccttg taaccacgct
     5161 tcattttcag gtgttgtttg cagggaagag atagcttcta aaagttcttt ttctagcact
     5221 tgctgttctt gtcgtatctt cttgatgtca tttccgacat gaaccatatc aattggttct
     5281 tcttcttcaa acgtatctac atagcgtgga atatttaagt tatagtcatt ttctttgatt
     5341 tcatcaaagt ttgccaaatg agcgtatttc tcgacatctt ttctttcagc ataggtttcg
     5401 aggatttttt gaatgttttc ttccgataat ttattctgat tttttccttt gacaaattct
     5461 cgactagcgt caatgaataa tacgtctcga gtttggcggt tctttttcaa tacaatcacc
     5521 gtcgttggaa tcgatgtccc gaagaacaag ttcgcaggca taccgatcac agcataaata
     5581 ctgccgtctt ctagtaattt ttgacgaatg accccttctg cagcgccacg gaataaaact
     5641 ccgtgtggca agacgatggc catagtccct gtttccttca aatgatagaa accatgaaga
     5701 agaaacgcaa aatctgcttt ggattttggc gctaattttc cataacgatt aaaccgagaa
     5761 tcgtctaaga aggtcgtatc tgctgaccaa ttagccgaat aaggtgggtt cattactact
     5821 gcatcaaatg tgtaaggttc atctgttggc caatccttat tcaacgtatc cccattgcgg
     5881 agattcattt cttcggcatc taccccatgt aaaatcaagt tcatttttgc tagattgtat
     5941 gtcgttgtat ttaattcttg cccatgatat ttaacgttat ctgggtgagt taagtagtta
     6001 cgcacattta acatcaatga acctgaaccc atggttggat caaaaacact aaagaatcgt
     6061 cgttcttttt gatccaacgt cacgatttgt gccatcatat cagaaaccat atgaggcgtg
     6121 taaaattctc cggctttctt ccctgcttct gaagcaaatt gactgatcag aaattcataa
     6181 gcatccccga tcacgtcccc atcgtgacct aaaacttcca cgtcattcaa tttcttaatg
     6241 acttcggtaa tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt tgattggaga
     6301 tccacatcat caaataaccc attaaattga ttgtaggtag atgccaattg cacaaaggct
     6361 ttgtttagat cattcaattg gaacgttgct tgttttgctt gatccgctaa gacgttgaaa
     6421 agatactctg gcgaaatcgc ataccccaaa atatcaacga ttgttgcaat cagatcttct
     6481 tttgattctt catctgaaag taattcgcga tacaacatcg tttgtttgct taccgtatca
     6541 tattcctcta aggattcatc tgctaaaaga accacttgtt ccaacaaacg gtcggataaa
     6601 tatttataga aaatcagtcc caataaataa tttttatatt ctgacgcatc cattttgcta
     6661 cggagattat ctgccgcact aaataatttt tgatttaatt ctgcacccaa aaagatacac
     6721 tcctatctct tatttaaagt tgctatatac cctcttattt tagcatactc ccttttagaa
     6781 aaagcaaaaa aaaaaagaaa gaaacttatt cttgctaata aactacgcga aaggagtcta
     6841 acgttgtttg atataactta gactgatcgt taacttattt tttatatttc tacatagtta
     6901 tctttagaac catttcagat acatatgaaa caattacata tgattttttc ataaaaaaac
     6961 agtactgtct agtagtataa aatatacaaa tttcttaaaa attttttcac taaaatcact
     7021 acctgaaaca gtctaaaaca cttatatatc aacgtttaat gaaactatct ccgtttcatt
     7081 tcagatacaa ataaatatag tcgggctcca aatccgaaaa aaaatacccc cagtagctta
     7141 tcctaagcta ctggagatgt ataagtacgg tcatataaca acggggtagg gtaaataaat
     7201 gaaaaagatg gaagaatcat tattcaataa cttttttaaa tacttcgttg taatcagtta
     7261 cctgtccgtt cttaaatacc acagaataat cttttttccc attttcaagt aaccgaagtg
     7321 gaatatcttt accaactttc tctgtcactg cattactgat acctgttaga ttagctaata
     7381 aatctgataa agattgagca tctgtagaaa tctctgtatc agtatttatc gtgattcctt
     7441 tatcttcatt tacaagtttc caagtaggtg gtatagctgt gtatgtttct acaaatgaat
     7501 taagtttttc attaagtgac ttctctttta tatttccatc taaaaactct gtatatatgg
     7561 cttgagctat actaaaacaa agctggcctt gttctaataa ttttacatca ttagttagta
     7621 aagctgtgtt cacgttatca atcgcttcaa gaagagtatc tttggtgtcc ctaacagctt
     7681 taggtgtgcc ttctggaatt tccctacttg atacctcgtc cattttatct tccataaacc
     7741 ccttaaaatc atatctttct cccaaatcca tagaagtttt tgagaaagct ttcatttctg
     7801 agtctatttc ttcaataata tttaacatgt ctgatacata ttgtttaggc tgattcgttt
     7861 ttaatctata tgtggtaaat atctcaattc ctccaattat caataaaatt gccaaacaaa
     7921 tccataataa ttttttcttt ttcatttttc ctcctataca ctgctgttat aacagtgact
     7981 aatgtaaaga ttttcccagc aatcatcaga ctattattta cagggaatca aaaaaactcc
     8041 ttagtaagct tacaccttta ggagttcctg tttgaacggt atgcataata catttaaatc
     8101 aatttaacat taacacctca gtatatggta tctctacata tacacggtct ttttttggat
     8161 agtactcgac atttatattg atagcacttc cattgtctaa cgtagcttta gcccggtacg
     8221 tgttatcacc attatcatga gtgatcgtca catcatcaca tgtccgattt aagttatact
     8281 gttcttgtaa aatctgagtt accaatggta cagatgactt ctctagtcca gatgaacccg
     8341 tcattcttga aaaaattata cctataatag ccaatacaac gatacctata atgacaaact
     8401 tcttattcat atttacttta ttcaactttt tatctcctat ctccaaaatg attttctctc
     8461 atcagtaact cattgacatc cccaatagta caccaaagat ggctccagct acccctgcta
     8521 tcatcaaaat cgtacccatt tgttcatctt tctctcgata taagtaaccc ataataacag
     8581 caacagcacc aaataccaca ggaataaatg ctaatgatac taccatagaa atccaaccaa
     8641 taatcaaata cagcttccct gtctcttgtc catgtacgat ttgttccttc atttcattaa
     8701 ttgtctgctc agtacttttc tttactgtgt ctgttccggt tgtctcatct gtttcttgta
     8761 atgctccgca aaactggcaa tacttacttt catttgttat ttctttacca cattttctac
     8821 aatacatgtc ttctcctcct aaaatcattc aattgcttat tagctaactg tttactttat
     8881 taaatacatc agaaaacagc tcatttattg gtacacttaa tatctcagaa agcattttca
     8941 tttgataggg tttaggaatc gttctccctg tttgccacga acttacacat tgctgtgtaa
     9001 cattcatttt tttggctaac tcagtttggg aaagtccttt ttcttttctg tatcggctga
     9061 gattacttac ttttttcatg attctcccct tctgttttat tatatacaac aatatgatgt
     9121 atttcaactc ataaaatata taaatacttc aaatgtcatt acaaatacaa caacttgttg
     9181 tactctactg agaagggggg tgtattaatg aaacagaagc aatatgcaaa ggtcattaga
     9241 gaaaagcgaa aagcactcgg gtggacacaa aaagaattag ctaaaaaaat cttctctaca
     9301 caacaggcag tagcaagatg ggaaaattct gtaacagaac ctaacctcga tagcttaaca
     9361 gctctttcta gagccctagg aacccctgta agccattttc tagacaatgt tgacatagat
     9421 tatgaggaag agtttttggc tctctatcgc tctcttagta ctgaagatgc aattcgaaca
     9481 attgactata tgaagctatt aaaaaggcaa gaaaatgaac gcaatcagct attgaaagat
     9541 tgaaaaataa ataacccacc gaactttaac ggtgggtgta ttgagatgaa ataagattaa
     9601 gagctatgga taacctgtct agtttaatat aattgggtct cttctattcc ttactctccg
     9661 tccatcatct cttgttacac ttgtaaattg ataaatagga actaattcaa ctcctgataa
     9721 tatcaattct tttattactt catctatccc tgcccctttc gctagatata ctaaaaaact
     9781 actgcttgct ttcacattgt atagtttctt aatatcctta gaagctcgtt caagagtgaa
     9841 tccttgttta acaaagtagc ctctgttttc tattaaagca tttttcacgc tgttatccct
     9901 gacatttcgt aggcgttcac aaacagtgtt aataagttct ttttctgtca ttagatatgt
     9961 cccttgccac gataagccct gtaaaacttc atgtgcttca tctaaaatca attgtttttc
    10021 cttgctaagt tctgatcggg aattttgagg aaatactctt ttagcctctt tttcgttaaa
    10081 acatatctta acccattcat aagaaaaata ttgatatgta aaatgaaatt tttccagaag
    10141 tggaaggata tcttcattca atttttgaat cacagaagtt gcattaaaaa cgtctaatcg
    10201 atagacattg cttctcttat gtttaaagtt tcctaacgct ttctcttcct ttaacctatt
    10261 taggtattcg agcatcttca aaggaacatc ttcatcatct aattttttta tcaatcctat
    10321 aaaagtcata agtgatagta acttattaca tttatctatg tcataagttt taccatagta
    10381 agaactcatt tttttagcta attgttcccc cgacaaaata caagtcacac tttccttact
    10441 atcatcaaaa aaattaacat cagaaagcaa gacatcatag acacgtcgca tttcctctag
    10501 ataattcctt attgtcctga aaagtttgtc tttcattgat tcaagagtgt caaaaagtac
    10561 ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac aagtctaggt tctctaatag
    10621 ccaattaaat gtttctaccc gactgtcttt ctttaaaatt agcatcacaa ctccaataaa
    10681 attttcactg atatcacaat tactggaatg acaataaaaa atggaatgcc cagttttact
    10741 ggtaaaaata ctagcagagg gattatgatc gttgtgaaac agacatctta agtttttact
    10801 tgacttaagt aatttattca tatcaatggt taacaatctt tcataaatct cattaaaaga
    10861 catgtcggag gaatcaaaca ggcagtcttt aaaccactgt ttcatttctt ctttgtcgtc
    10921 attttttatc aacttaacaa aatcggtttc attgactagt tcatactctc tccctgaatc
    10981 actttgacaa tttttagaac atgtcatggt aaaatcaatc ggaagctcag taatatctaa
    11041 catgttgtct tcattaatta ttatcactgc atctgactta tatcctccaa aaaacattct
    11101 attcgaagca tttacattgt catcacaccc ggggatgttc tttttcaagt attcgtaaac
    11161 agcaaccatt ttaccatagt cagtaattgc ttcttttaat agaaagacaa tcttgtattt
    11221 ttctagattt tcagagtacc gaatactttt ttgtatcgca aacgcagaat tatgaactaa
    11281 attgatagat aaaacctttt ctatgcttaa gtatctacta tcatctttac tcaaatctac
    11341 taccttcccc ttctcatctt taacagtgtt atcgacatcc agaataatta ctctggtttc
    11401 cacaaaactc tccttgtcat tgcctttatt ctttgtcttg cttggaataa atgattgtga
    11461 tgaatttagt atctctacaa actcatctct tgtaacttct ctatagttat ctaaacacct
    11521 atctcttaca tcagtttttt ctttttttgt aactggcttc tctaataatt tttctttatc
    11581 tacataaatt ggaatattaa tcattgatgt ttccatttgt gtttcctcct tataaaattc
    11641 tgttaaagac taaaacatac agataataaa aacaaactct ttattactat atgttttagt
    11701 cttatttgtt tactcaacct ttataccgtt ccatgaaact atcaatatca gattttttaa
    11761 atctaatgac cgtatcaatt tttataacag gtaacccgta ttgagaaaca tattttctaa
    11821 tcgttcctac tgatacacct agatattcac ttgcctgctg atagtccata tactctagag
    11881 tgactccaga aataatgtct tctagcatag gctttagcac tgtaattatc tctttcactt
    11941 gttgttcaac ttgtatagaa acaatgctat caatgatttg tagagacata tttccccctc
    12001 ctttcgtgat tgcttgaaca aattttctaa gaattatctt cgtatttttt gctcaaaata
    12061 aaagtatttt gttattaacc gattaatcaa acaaaaaatg attaccagtt catcgacata
    12121 cacataatac ctcgataaaa aaggggtgtc aatagttttg taaaatttat ttacaacacc
    12181 ccttttttga ggtatactaa ttttaggagg tgtggtcaat atgataaaac gtccaccaat
    12241 aaattattta gaacgaaaaa agatactcgg aacaaaaata aaagctataa gaaagagtaa
    12301 aaaattaaca caaccagcat ttggtcttat gattaacaac ggtcaattaa ttgacaaaaa
    12361 gactatctac gaatgggaga agggaaccta tttaccaata ccagagcgat tatcccgaat
    12421 tgctgatttg ggaaatatga gtatagagga gttagtttgt ggcaatgtag aagaatatat
    12481 tttgggaatt attctttata gagatagcat tgtactagat ggtataacat ttccagataa
    12541 aaacctgttc cagcatcttc gtcaacagtt cccaccagta cactctaatt tagatacatg
    12601 gctggataga tattccaaat tagaaccaga gatgcaagaa tttattgcta acaagacttg
    12661 taataaagtt aaaaatgaaa aaattagtct tttcaatatc ttaaaaatag aagaattatt
    12721 catcaatgct attgtagaag aatttgacaa taacattctt ttcctcacta gcagtataga
    12781 agaactacta gaaagaatgg tagatgaatg gctacctatt caattgaaag acatgtctta
    12841 tcccgaagaa gctgtgagag aaattactga taatataaac aagctagaac aaacgatttc
    12901 atcaattggg aaaaaataca ctaagaaaaa aatgaaggga ggtgatacca tctagtggta
    12961 agtactcctt gtaaactaag aggagatgat ttcatggcaa aaatatcaaa gtacaaaaag
    13021 aaaaacggtc aagtggcgtg gatgtataaa ggacacattg ccaccgatcc acgaactggt
    13081 gaaaaaataa atactacgag aagaggtttt agtagcaaac aagaagctca aaaagattat
    13141 gacgagtaca gacatcaaat attatacggt gttaaaaaga aagcacctga tatgacattt
    13201 gaagacctgt ataatgaatg gataactcat cagcgtacca gtgttaaagc ttcaacaatc
    13261 gcaatctcag taagatacgc aaataatcaa atacttccag catttggtaa gcttaaacta
    13321 tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg aatggcacag taaatatgaa
    13381 agttacgatt atatgagaaa acagactgca caaattttac gctacggggt tgcaatgcaa
    13441 tatattgaca ataatcctat ggaaaaaaca cttcttccac gaaaaaaaga gtatgagaaa
    13501 aatcgtaaat tttactcaaa agaggagctt aataatttac tggatgcttt taaagatttt
    13561 ggtaacatga aacaatacgc cttcttcaga ttattggcat acacaggtat gagaaagagt
    13621 gaagtactcg ctttacagtg gaaagacata gacacgttta ataaagaact acatgtcaat
    13681 aaaactcttg ctgtagatga atttggtaaa gttataattc aatctccgaa aacaagagct
    13741 tctagacgag ttatctcttt agatactgag actctttcta tcctcaacaa ctggaaatta
    13801 cagcaaaaag aagagtattt aaaacttgga tacaatacta gctctaaaga gcaacatgtt
    13861 tttacaacag ttaaaaacac tctatacatt ccaaacactg ttaatgattg gttaagatat
    13921 attttgaaaa aatataactt gcctcgtatt acacctcatg ggtttagaca tacacatgct
    13981 agtttattat tagaagcagg agaatctgtc aaggtagttc aacaacgatt agggcatgaa
    14041 aatagtaaag tgacattaga catctatgca catattacaa ataatgcacc taagaaaaca
    14101 ggtcaagact ttgctgatat gatggctcat cagtaaaaga gctggtcaaa atctggtcat
    14161 ttctagtata caggcaaaac aaaaaagcta gaacccttat atatcaaggg ttctagctcc
    14221 tataacaggt ttacccaaca ctgccttcca atgactcttt tgggaatcag aggaaagaat
    14281 caggctttat agagatattt catctaacaa attactttag actgacagta tatatcagca
    14341 ggtactgtca tcgggaacgt agccaatatc gtatccaaaa cagcaggtag agaagctatt
    14401 tgaggattca agttattcta tttcaaccat gaagttaagt tcattaaaaa taaagatagt
    14461 tggtatttca ataatttttg tatagagtta atcactttat tgatgctaat tcatcttgat
    14521 tggtattata atcgtattca agttgcgtgg cgtgcttttg ctagaaaata tataactgtt
    14581 ctttataaag aaatataagg attaaacatt ttttatcata gagttttact tatctataga
    14641 attatgtctg ttcctaattc agtttgatga attaactgat aaaaaaatat ctactattta
    14701 aagatacagg gataagtaag taaaaaaata acatgtcatt agatagtaga cagttccaac
    14761 tctttattta ccttttttgt atgctgcact gtcaatccaa gttcctaaat tgttgtatcc
    14821 atcatcactt atataatcat attggccatc aataatttcg tcaaaccaca aatattctcc
    14881 atctggtttt tgcccaatta ttttaattac tgattgacta gtagttgtca tctggttaaa
    14941 atcttttatt ttacctatat taacggccaa aatagcattt cctcgcttat aactctcctg
    15001 gatttcatat ttaacatatt ctcgatcaag agtttcttta cctatcagca ccacagtcac
    15061 tgatgttcca attaattgat tatctatcca gttttttata gcaatatctc cattacgttt
    15121 aactttctca aattcagcct tatctacaaa accagcttcc tttgttcctc gcaaagtcca
    15181 gctgtttcta actaccattg ctcttgttac atctgcataa tggaaactaa aaaaaaccct
    15241 tctcaccata ttaatcctcc tgaatactat ttattaaact gacaatttgt tcaacttttt
    15301 tatctacttc tccttcagta tctaattttt ctagcgcttg aaatttactt tttaaggaat
    15361 catcaaaata atcactgaaa ttctcttgaa tcttatcaaa caaaacctta cttgcacctt
    15421 tggtaaatcc aatcggaact actatatttt cattttgaac agataattca aattcttcaa
    15481 tcattccatc tgctgtaact atttcacctg attcaagttt gtttccaaaa acaaaaatac
    15541 taatcccaga ctctgcaata atgttttctc gatatcttct ccactcatga ggcatatcaa
    15601 ggggaagtgg tcttaaagaa agtacgtctt gtatgttatt ttttcttaaa tttcttctct
    15661 gctttagaac tcctgaaaca atactattac caattccaag tccgtaacct gatactattc
    15721 tataaccgga ttcagaaagc ctatatgcta atttctcgac aaattttaat cctttcgatt
    15781 cagatgtaaa tggagtataa tcaacagcac ttcccgaaat aaaaatagtt tttctcaaat
    15841 acttttttct aatacttttc aaaatatcag taatctcaga ataatcatct acttcaacaa
    15901 cgtttatcga aaatctggac aaatcattga tttgtagtct tctttttgtc agttcataat
    15961 tatatctctc ttgatcaaaa aaatcctcag aatcgacaaa attttccttt aatatttttc
    16021 tcattataca ataatgaggt ctttggtttt ctctcaaaac ccatcttata tctgataaaa
    16081 ttctttctaa attagggtct gtaaaactaa atcctaaaaa gagaaaagtt tttgttaaca
    16141 aatctccttt taaagtttct ttaaataacg cgtacgaatc atcatcatat ttttcataat
    16201 catctcttgt tattactgtc gaactgacat catctatatc accatgcatt ttataaacaa
    16261 ttgtatccac atttggatta gttgttgcta actgagtata atttttctta acctgagggt
    16321 ttttataagc ttctcggatt gatttttcta ttagatgatc ataattagtt gtccaataag
    16381 tttcaatagg taaacttgct agtattcgat gattttcaga tatttctaat tcttcaccaa
    16441 aattatccat aagtatctga ttcaaaattc ctcttgatcc accattttca tttttataat
    16501 attgagccag agtaactaag tctgtttctt ttttagaatc caacccgatt tctgttgcag
    16561 gatcattaag tagttccggc caacttacat atccttgtga catcgataat cctgcacctg
    16621 caaatattgc tgcatttcct ttttcaatag cttcagagaa cctctttatt aaaactttct
    16681 tatccattct acccggttcc tttcgattca gtaaattgat tagagattag tgaaaatggt
    16741 gtttttatat aaaatatcta atgtattact tcctttagtg cattccacag catctaaagc
    16801 ccattttttc aaatcagctt ttcgtaaata agttaattca cttaaattta aagaatattt
    16861 tatttgcaga ttttcttgcg aagaatagtg ctttataatg cttctaacat cctcggtgct
    16921 catttgagga ttactttcca atcgtggatt ctttttttcc actattgaag ctgtcgtcag
    16981 ttcgctatat agccatggcg aatacgtaaa tttctgttca ttagtgattt cattgctcaa
    17041 actaattgaa ttaggtgtat taagaaaaaa cagacattct gtactatcaa tcatattatt
    17101 taaagctgta gaaagcatca tatgaacatg actagttgtt acatttcttt tatcataatc
    17161 atatgttttt gtttgttcct tatagcaata tttttggtct atttttttta ataaatcaga
    17221 actgtatccc caaaccgaag aatcaataaa tgcagtaaga ccaaaatttt caaatagcca
    17281 tgatgcaaaa cgtatagcta atttttcatc agcatgagag tgagatataa aaatatctgc
    17341 ttttatagtt ggaaaccaat ctttaataat ttcgtctgca tctagaattt tgctgtcctt
    17401 agaataataa tcaactaaat cattttcact ttcaaataga ttttctattc tcttgttaat
    17461 agatttttgg ttgtgatcta tttgatttac tacatgtgta tatgattgcg agcttgagga
    17521 gaatgcattt aagtcagcat ttgtaaaatc caattcatat gccttataca aggatatccc
    17581 tccattcttg tattttgatc cacaatttat taggcaacat aacagtatac cctatcgtta
    17641 catatcccat tcattattat accagtattt cttcgtgaca cataagggtg taacataata
    17701 atttcaaacg aaatgactac aagtagtcat tgaagcaaat cttcataaga cacctgtaga
    17761 atatctttga tggctttcaa ttgatccaac ttaatgtgtt ggcggccacc ttcaatctta
    17821 accaacgttt ccctagttat agcaatttta cgaagctgta ggtctctaat cagctcggtt
    17881 tgaccaattc ctttttctaa tcggactcgt ctaatattgc taccgattac attttcttta
    17941 tcaataattt tttcctcttt caagaatagc acaccttttg gactaaaatt agtccttttt
    18001 cttattaatc ttaaagattc ggtatgctac aatgggacta gtattagtcc atattcaatt
    18061 ttaaggagga atttttttga agaaatttgc aatcattcta acttgcgctt tactcatcgg
    18121 aactataagc gggtgtacca cttctgacac aagttctaca agtacggaaa ctagtacaac
    18181 aacctcagaa aagaattacc caatacattt ttttccggtt ccagatggat ttgaagctta
    18241 ttatcatgat aaaaaactag atgttccttt atcagaaact gaatctactg aaaagatttt
    18301 gccaattgaa attgaaagaa atcaagacga tataaaacta aaagctgatc ttcccttact
    18361 gaacagcaca caaattgata gacatgaaaa tattaaagtt aatattgaaa aaggagcgtt
    18421 agcacaactt tatactgaaa aagttgaaca attttttgag gctggtgcca ataaagactt
    18481 ttcaaaaata agcgattatt cggataactt ttttaatgag acccaagatg aaatcacgaa
    18541 ctcaactttt atggctgaag atatgtacaa tatgaagttg aaaaaaataa agtcgtatga
    18601 ttatccatta aatctaacat taaataaagg gatactctct tttgtattag caggttacgt
    18661 tgactatgaa tatacagcag attatttgga gacgcccctt caacacgata ataacgatat
    18721 taattttaga tttatctaca attcaaaaag taaaacatgg ttagttgatc aattgagcac
    18781 tataaatacg ggatttcatg aattacctaa gcctgacaat gaaactgctt tggtcattaa
    18841 aacattctaa aaaagaaacg ttgaaggaat aattattctt tcaacgtttc ttttattgtt
    18901 tttcagttta cggtcttacc tgagcgaata atctgatttc taaatgattg gaaaacttct
    18961 tgtggttgat aataatctgt atctatttca aatgtttctg agaataattc attgaatttt
    19021 tctactgaaa tgatgatttt accattctcc tctcgactgt tttctattat ttctgcctct
    19081 aattcaaata aatctagtga cgaactaaaa tcataaatcc tgtcatattg aacaaaaaaa
    19141 tcaagaaaaa gttgctcaaa ctcttcctta tttatcacta gtgtttcaag cggaacaact
    19201 ttattttcat cagccattct tccaatttcc tcactttcat tttcaattgt ccattgttgc
    19261 ggacgtatca gattttctct atcatttttc agtgtataga tcacttgtaa tacacaacaa
    19321 tgctttgtaa acttattttt ttagttagtc gaatcttttt aaatgtgcgt ttcataccat
    19381 gcgcttgata tattttctcc tattttttaa atcgtttatc acaactttta tcgttttttc
    19441 ttctgaaaaa aatcttgttt acatcgttac atagtttcca aaaagataca ttactagtag
    19501 aaacaacaag attaatttta cttcccactg aaatgggaag tatattttaa atattttttc
    19561 tccttcaact tacactataa agtatcttaa tcacacgata tgctagccac taaattcatc
    19621 atatttgatt ccttttttaa gataatgtag catcttttta tccaataacg caattgtttt
    19681 taaggataaa tttcttaaga tggtacattt caaaatggca tttgacatat gaaacaaaaa
    19741 agaaagaaaa gagcataagg gaaaactgat agcaccttcc tacaggaagg tggctaagtt
    19801 ggctgtgcca actggttttc tttcaaaatc atttcataat ttttgatatc ataaaaaaat
    19861 ccattttgga cctattttcg gtcataattt agtacctact tttggtcata gtttcgtccg
    19921 tagttttggt catagtgact aaggcttttc tgttcacaaa attggtttaa atttgctttc
    19981 tttaacactt catttatatc atagcaatta taatgtttac acaacatcat tcctaatttt
    20041 aacggttgtt cctctttata ttttttaagt tctacatttt tttgcgttta attacttttc
    20101 tcttttcttt atattccgct ccaactttct ctttaatagt gataatagaa ttacatattt
    20161 ttgttaaact tccttaaaaa aattggatct cgattactca aatttgcttg caggcttttc
    20221 taattgcttt gttttttctt cctaattatt tgattttatt tccattttct tctagtgaaa
    20281 atttattatt tttaataatc gtacgcgtag aactgatttc attttttgta tctgtttgat
    20341 tatctaacgt ttgaaattca aagttttgat tggctttatc aatatctttt tatactactt
    20401 tatttgcaag atatattttc ttgcttaatt tggtcatagt ttcattcgtc acttcggtga
    20461 tattttttta atttgcaaat aaaaagagtt aaaccgatat acattaggtt caactctttt
    20521 gcaggtttca tgggtgtact atcactttta atctgataga tgtaaacctc tctttatctt
    20581 tttgttactt caattttcaa caatagctcc tttataggtt gtcaatattg ctctacgtat
    20641 tctggctttt taacccatta tttctctaaa gtggaagaga ataatcgctt aatccccact
    20701 aattccttgt cgtaaattca tgtcaaatac aatttttaaa agccatttaa ttcatggatt
    20761 atctcttcac ttttttctag ataacaatat ttcaagttgt tttttatctc atgtttcatc
    20821 tttaattctt cttgaatcat cagttcaata taattagtga ccgtgatttt ttcatttgtt
    20881 gcgttcttta ctgattcaca taattcgtca agttctaaga aatcatgcgt actaatcttt
    20941 agaattaatt tcatgacaat tccccctttt atttttttaa tagattatcg aaaagcggat
    21001 taggatcatt aagtgtatct ctgaataact cgttgtcttc ataggtaaat cttcgtcttg
    21061 gttttgatcc cttatcattt tcacggattt cactatcaat aatcactgtt tcatgatttg
    21121 aatcaaattt tttcgctgac tttctgtctt caacgatatt gattttttgt gttttttctt
    21181 tcatttctcc actatctttt tgaacgttct cccgaacatc tactgttttg aatccttgac
    21241 tacttgtaga actttgtaca ttctctctta catccattga tttaaaccct tgactacttg
    21301 tagaattttg tacattctct cttacatcca ttgatttaaa cccttgacta cttgtagaat
    21361 tttgtacatt ttctcgaaca tcaattgtct tagtaccttg accatttgaa gagctttgta
    21421 aattctctct tacatcaaca ttccgtccga catgaccatt caatgaacct tgaatatttt
    21481 ctcggacatc tactgatcgg ccaccttgac tacttgtaga attttgtaga ttttctttga
    21541 ccaatttttc taatccggta tttgagtttt tagcttcttg gattctttct ttggtcaacg
    21601 cttctttttc gtccgtatta gctcctgtac gcccttctac acgtttcctt aacatttcct
    21661 cacgattcat tgcttcaggc gtgtatttag cttcttgtcg cttctgatta attaattctt
    21721 cagcagactt agcttgaccg tgcatagcat ttttacgttc ttcaatatct tgttgaactt
    21781 tttgctgaat tgcacttaca ggattattat tcgattcagc attatttttc attgcttcac
    21841 gcatacgttc agaactagac ataattctat cggcattttc aaccttagca ccatcttttc
    21901 tatccgaaag acgtgttggc atggaatcag catattttcc agtttcatct tctttatttt
    21961 tagctaacat aggtttgcta tttttattaa tagcggacac tgtaccatca tctaaacctt
    22021 ctttgaactt attcttggta tcattagcca tatcacgcat actcttaaat ggttttattg
    22081 ctctttcact agccattgta gctccatctg aagctaaacc tgataatcca cgttcatggg
    22141 catatcccaa agctcttcca gttttgccag ctttttttga tagagtttcg ccgaaattct
    22201 tttctggttt tcgatcttct ccttctccac tgtctgatcc atttccattt ccgcttcctt
    22261 tagcacgatt aaatccagtt gatccttttc taaacagcat tgcgcccata ccaaaagcag
    22321 aagcaagttg cccatagcct tctttgagtc caatatcaac accaaagtat ctcatgactg
    22381 ttccactgcc ttttatcagc acaaacacag cacagatata agcaattgtt tttataaaaa
    22441 tatttgtgga gataccttgt ccagcattta aaaaattgat aaacatagca aacatagata
    22501 gtccaaaccc ttgaaatcca actgttaagt aacattgtaa aatatcggat aaaacaactt
    22561 ttgaacgttg tcctgtttca atatctgtcg caaaaacaag aacacctaac acacgtttaa
    22621 atgcaagttc taatattgct gtaatgatca caaacgcgct gaacacatag gcgattgcca
    22681 acgctgtcaa cccaatcgaa atcccccaaa gatttgcttg atatcgataa taacctgatt
    22741 tcaagctatc agaaaatgtt gataagaagt tatcagaaaa ctttgtggca acaaattcat
    22801 tattagaatt ttcaactaat tcatagcgaa gattatccgc agctggattt tctttttcca
    22861 atttatcaat cactttatcc gtcaacactt gtgttaaatc tgtctgttga aaattttttc
    22921 gtgttaactt atttcgatcc tccgttttat caatgcttga gtattgatct gttttattaa
    22981 tatatgccag atctgttact ccttgtttta tcaatgacca agcgactccg tcatctgaat
    23041 ttgtaatcgt agtagcatca ttgtaaaata ttttggcaaa ttgaataccg ctagaaatca
    23101 ttgttggcat taaaagaatt aacgctacag acatcactat attcattcca acagatctta
    23161 aatctattgt tccttttcca gtaatcatct tgtagccaac aaacatcaat gaaaggatca
    23221 ttaatccaac gacaattgta tttatgactg attgataaac attatttagc cctgtacttt
    23281 caatgaaatt gaacaaatcc aacacatctg gaatcatatt ttgaatcgaa tcagtcacag
    23341 taaacatgcc ttttaccaca gcccatccaa gccaaatccc gaactgacta aggaaatctc
    23401 cattgtattt ttttaggtaa ggtctataaa gagaattatt caaaaactct gtttgacttt
    23461 ttgtgtcatc aaaccaattg aaaatgctag cttcaacaat attacttgta aaaacaacgc
    23521 taatcattaa aacaagtaca ctgagtgcta accagtttat ttttctacta acgatttttt
    23581 ctttaattgc tttcatagtt ttctccttca gcccattttc ttaggctctc agagagctgc
    23641 tgagccattt tttgattaat tatgatatga gttacacaat tgtcattttc agctcttaaa
    23701 tcgagaacta ctgtgttgaa gcagatactc tcgattaatt cgagagtatc tgtattttga
    23761 tcaagacacc acatttgatc tattaagcga tttttaatca tgattcttct cctttcaacc
    23821 aattatgcat agtaatttca ggtaactctt tgatttcgaa agcttttttg aactgatcta
    23881 taggctctac attttctaaa aattgacttt tatatctttt ctgaagtcca ttcaaaaaat
    23941 atgttacata atcgtataac ccttcttcag tttttctttg aaaaaagcat gcttcatgtt
    24001 gttttataat acactcagca ataagatact gagtattttc agataaatat tcaatgattt
    24061 ttctgatatc ttctgtatct acattagcgt ttctcaaata gtgatacact tgaaataatt
    24121 ttcgaccatc ttcgttattt gcgtcataaa gaacactaat cttactgtaa atcctcttta
    24181 tattaatatc ctcttcttcc ataacgagag tagtctttga tatgttctgt gaagtagtct
    24241 ttgtatacgt atatacaaat ttgtacatac ctctaccttt ttttaaagag acatatctct
    24301 ttttttcgat acccctctga cgaattttcg gcatatactc ctttttttcg caatccaaag
    24361 taggaaaagt aatttctatc aatttatgta catttaaaac aatgtacata acatttgata
    24421 atgtaactgc tcttttctca taataaatat ttctaaaaac ccttttgata atcccctttt
    24481 tctctaagta cacaattgca tcttttatag ctcgttctga taatcctgtt tttttgctta
    24541 attgcttata tgatttttgc aaaatatctt caagaaactt tttttgataa ccaagtagct
    24601 gaccatcatc gttaaaaatt tttttaggtc tataccaata ggtaatttct gctaagataa
    24661 ctattgcatt caaatagggc ttctcaacac cttttttcgt tttttttctt aattgatcgt
    24721 accatgtgtg tggattacat ttccgtcaaa atttatttct ctaagtttgt caactacaac
    24781 atttccagaa gaaaacacct tttcaccttc ttttttgata taatagctat aaataaagtt
    24841 ttctcagcac tttattattg agtgttcccc cagtctgcaa acttttggga acactttttt
    24901 tcttttttta aagcattttt ttataatttc tacttcatca tcttccaata ttttcccctc
    24961 ttttcattcg agcaaacata aactcattaa ctgccttttt cgaataaaat tttcttgccc
    25021 ctaattcaac tacgggcaat ccctcatttc tcacagcatt ttttaaaaag ttttcactca
    25081 catttaagta ttccgccatt tctttttgat tgagatattc ccttgtcatc cccgcatttt
    25141 cttgagcctt ttcaatagct tttgtagcaa tttgataaaa ctgctttaga aacatttcct
    25201 cctgttcttc tgaaatcatt aattttattg cttccacaaa aacctctcct ttttaattaa
    25261 ttattctata actcctctac ctttataagt acaaataaat acaaattgcg taaaaaaatg
    25321 tatttatttg tatttataag aataaagtat catactccag ataaaaagta aatactttta
    25381 aatactttta ttttataaat atgatatact atctttaaaa ataaaaagga gaaaaaagat
    25441 gaagccaaat ccttcagaag caggaaaacg aatcaaacaa ttacgccttt catgtggttt
    25501 tactatggaa gaacttggaa ggaaaataga taattcacca cgtgcgacca tatccaactg
    25561 ggaacgtggg accaatttac caaatccaca aaagctgaaa ttattatcaa ctatcactaa
    25621 ttcaacaatt gactggatta aatggggaac tttagaagaa tatataactt cataccttat
    25681 cgatataggg tatgagctat atattaagga cttcccagaa atacctcaca aagtctttaa
    25741 agacattcaa gaaagatata gtgatacgtt ttcgctagat aaagactatg agttattgaa
    25801 tcctataata aaaaatatat ttacaaaata ttactcaaaa gattttgaaa tttatctaaa
    25861 tgagatactt gctaataata tcaatcctct gattgaagag tacgctaacc aaagacactc
    25921 tatctctaaa gagctatttt tcaaaagagc caacagtaaa cttcaagaca agataagaaa
    25981 tggtgatttc aaatacggtg aaaaagaaag aatgattgat tctttaaaac agctattaga
    26041 cgaaatggac ttagcc
//
LOCUS       DAZKCW010000036        25661 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000036 DAZKCW010000000
VERSION     DAZKCW010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.036"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            161..2221
                     /locus_tag="ACG84Z_001728"
     CDS             161..2221
                     /locus_tag="ACG84Z_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFP9162572.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2304..2873
                     /locus_tag="ACG84Z_001729"
     CDS             2304..2873
                     /locus_tag="ACG84Z_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9162573.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3048..3854)
                     /locus_tag="ACG84Z_001730"
     CDS             complement(3048..3854)
                     /locus_tag="ACG84Z_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162574.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3992..5506
                     /locus_tag="ACG84Z_001731"
     CDS             3992..5506
                     /locus_tag="ACG84Z_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFP9162575.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5909..6892)
                     /locus_tag="ACG84Z_001732"
     CDS             complement(5909..6892)
                     /locus_tag="ACG84Z_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFP9162576.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6897..7544)
                     /locus_tag="ACG84Z_001733"
     CDS             complement(6897..7544)
                     /locus_tag="ACG84Z_001733"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFP9162577.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7629..8261)
                     /locus_tag="ACG84Z_001734"
     CDS             complement(7629..8261)
                     /locus_tag="ACG84Z_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFP9162578.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8277..8828)
                     /gene="coaC"
                     /locus_tag="ACG84Z_001735"
     CDS             complement(8277..8828)
                     /gene="coaC"
                     /locus_tag="ACG84Z_001735"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFP9162579.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8825..9562)
                     /locus_tag="ACG84Z_001736"
     CDS             complement(8825..9562)
                     /locus_tag="ACG84Z_001736"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFP9162580.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9559..10548)
                     /locus_tag="ACG84Z_001737"
     CDS             complement(9559..10548)
                     /locus_tag="ACG84Z_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFP9162581.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10806..11348
                     /locus_tag="ACG84Z_001738"
     CDS             10806..11348
                     /locus_tag="ACG84Z_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFP9162582.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11365..12450
                     /locus_tag="ACG84Z_001739"
     CDS             11365..12450
                     /locus_tag="ACG84Z_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162583.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12462..13268
                     /locus_tag="ACG84Z_001740"
     CDS             12462..13268
                     /locus_tag="ACG84Z_001740"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162584.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13269..14096
                     /locus_tag="ACG84Z_001741"
     CDS             13269..14096
                     /locus_tag="ACG84Z_001741"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162585.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14093..15166
                     /locus_tag="ACG84Z_001742"
     CDS             14093..15166
                     /locus_tag="ACG84Z_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9162586.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15594..18290
                     /locus_tag="ACG84Z_001743"
     CDS             15594..18290
                     /locus_tag="ACG84Z_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9162587.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            18355..18855
                     /locus_tag="ACG84Z_001744"
     CDS             18355..18855
                     /locus_tag="ACG84Z_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9162588.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            18867..19361
                     /locus_tag="ACG84Z_001745"
     CDS             18867..19361
                     /locus_tag="ACG84Z_001745"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9162589.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19382..20191
                     /locus_tag="ACG84Z_001746"
     CDS             19382..20191
                     /locus_tag="ACG84Z_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9162590.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20188..21009
                     /locus_tag="ACG84Z_001747"
     CDS             20188..21009
                     /locus_tag="ACG84Z_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9162591.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            21060..23159
                     /locus_tag="ACG84Z_001748"
     CDS             21060..23159
                     /locus_tag="ACG84Z_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFP9162592.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            23156..24274
                     /locus_tag="ACG84Z_001749"
     CDS             23156..24274
                     /locus_tag="ACG84Z_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFP9162593.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24313..25191
                     /locus_tag="ACG84Z_001750"
     CDS             24313..25191
                     /locus_tag="ACG84Z_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFP9162594.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            25337..25534
                     /locus_tag="ACG84Z_001751"
     CDS             25337..25534
                     /locus_tag="ACG84Z_001751"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFP9162595.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
BASE COUNT         8116 a         4461 c         5423 g         7661 t
ORIGIN      
        1 aagtacataa gttattattc cgattttctt gaaacaataa aaaatcaaaa aaaatactct
       61 cctaatagtc catcttcttt tgattttatt tatataatga aatcatctta tgaaaattac
      121 tacttcatgt ttagacaaga gtagggagga ctaagaataa atgtgttcaa aaagacgttc
      181 aaaacaacta aataaacacg cttgtcgttt agataaggaa cggtcgtgtt ctgaaaaaca
      241 ctacgttaag tttatgatgc gcacgatgct gatcagttta tctgtaggtg tctatatgca
      301 tgtacccgtt caggcaacga cacaaaccat caaggtcgta cgtacctctg tttctgagac
      361 cactgattcc cctatcacta ttactcatac tttcactgat gcaaatggaa aacagctact
      421 tcctgcattg acttcctata ataaagtcag ttatcctcca acgataaacc actactggtt
      481 aattcctaac aaaacattat ggacatcgga aaccggaagc agtgtgccgc tttctatctt
      541 ttccgatatg actgatccta caaaaggtga tcagttaaaa cagatcactg atattttgaa
      601 tcatgctttg acagatataa aggacggtgg aagcgcacaa gtttcttatg tatatgaaaa
      661 agattattca cagtttgaaa gaaagaaaat cgatgttctg gcagggacaa aagtttcgat
      721 atctgatctg gtagaaaggc tgaagaacgc agatggaaca caaggagata tgtccaaagt
      781 aatttcaaac aatgggaata tcgtggatac gactaataca ggaacatcta ctatttcctt
      841 gtcctatttt gatccaattg ctttaaaaac aatgactgca tctgctgtga tccatgttcg
      901 tgctgatcaa acagctatca aaggaaaaga tcttcactta agaacaggag agagttacgc
      961 ccctaaagat cttgttgaat atgtaacaaa aagcgatgga acttcaggaa ataaagaaga
     1021 aatcaaaatg aacgggacag tagatactac aactccggga gaatatcccg ttgtattaac
     1081 ttatatagac tcgaaaacat caaatgtggc agaaacaaca gctgtagttt atgtagaagc
     1141 atctgctgct tcatcgactg tcatcactca ttttatagat agtcaaacaa ataaagaact
     1201 tcaagcagaa acacatatga gtagtgtaaa tcgtattcct gatttgcgcc tacctgctga
     1261 attttctgat cgagtgccaa atatagattt atcgacttat gaacaaaatg ggaaagtcac
     1321 ttctatttct gattggatgc aagcaaacgg attagacaga aaaagtcact ggtcggagat
     1381 ccttgaagta cttcactcag aactgatgaa taataggaag caatcaggag gggaaattac
     1441 ctttacttat gtttatatac cagacaatcg ttcattagaa ggtcatgatc ttattgttca
     1501 tccaaacgaa aaaataaaca aagaagagtt gatccaatca gcaacaaatt ccttaggtaa
     1561 acccgtaccg ttaaaggatg tatcggttac aatcaatgaa gtaccattgg aggatggtta
     1621 tttgaccaaa caaacaggtg attttacgat tatgtatagt tatcatgacc cgtattcact
     1681 ccaagaactc catgctcagt cactattaca tgttttacca ttaaacaaac agatagatca
     1741 aaaagaacaa aaaagacaag aagaaagctt gtcagaaaaa aaacaacaaa tggctcatgc
     1801 agtttctcca acagggaaag taaaacaaac aagaagccta gagttagcaa gaatatctag
     1861 aaaaatctca gaatctaata aaacgataag gcaagaagct catttggccc cacaagtttc
     1921 tggattggaa aatgaaattt tagagcctaa aataaaacaa caatcagaaa aagaatttgt
     1981 tgctaaacag tcggaagatc agaaggaatc agatgaccag aaggaaacga agaaaaaacg
     2041 cttgtcaact attgattcca ccgatgagca tctgcagccg caagtaccac ttcctagtcc
     2101 gggaacaccc gcacctggtg gaggtattcc ttcttctgct ttaggagatt tcatgcgagg
     2161 tatggcagga acatgggtat acgctaatcg aaatgaattt gacgcagatg actggttctg
     2221 atttatatct ctatctgtta tagtcaaata agtagctgag tcatatgtta tttggcataa
     2281 tggagacgag gagggataga aaaatgttag ataaaacgtt accttacgca gaaatctgga
     2341 tgacaagacc acttcaacaa aatgttccaa tcacgccttt agcggaaggt tttgaatttc
     2401 gattttatca aaaagaagat gaatctgctt gggcggagat tgagacttcc gttggggaat
     2461 ttcaaacgac agatgaagca cttgagtatt ttcaacaaaa ctttgctcct tatcctgaag
     2521 aacttgaaag aaggatgttt tttgtagaga caaaaaaagg agaaaaagta gcaacctgta
     2581 ccgcttggcg aaaaaaatca agagagcaag tgtatccggt ttttcattgg ttagcagtga
     2641 aaccagatta ccaaggaaaa gggctcgcaa aagcattgac tgccagagtc ttgcaagaat
     2701 ttcctaccct ccatacggac ggaccaatct atcttcacac acagacatgg agccatcagg
     2761 cgattgctct ttataaaaaa atgggtttta cttttattgc tgaaaatcta gacggcacac
     2821 ctaatccaga ttatgaaaaa gttatgcagg ttttaagtaa attagataaa taacgaaatg
     2881 gtgaaataag tcctcagtat tgggataaaa aacgaaatag tcattcctca tatcttactt
     2941 ttttgagtta atactatcgg ataactaatg gcatgccata cattcaaaaa agaaggggca
     3001 gtgacaaaag tattgtcact gccccttctc ttgtttttta gcatgtttta tcgtttgatt
     3061 tttttaggaa taaaattctt gatgaacgta aatttttggt aatcgtttcg actatagagg
     3121 taaccaaata cactgaaaac aactgctcca ataaaattaa caaataaatc cttcatagta
     3181 tccatgattc ccacgtctaa gtaaccattt tggatgattg ttttatctgt tttaccatct
     3241 gcattttgac tttcaatgat tgtccgagtg atatctggaa catgatagac agtgtttccg
     3301 tctttactta actccacact attgatttgc tggatgatcg tatctttttg catatcgaat
     3361 tgcagtaatt tatctgctga aaattccaca aactcccaca taacaccaac tgtcatcgaa
     3421 aaacagaagg aaacaactgc tagtaataaa ggagtcaagt tcatggtttt tgtattttta
     3481 ttgagcaaat aaacaaggga aaagccgaca cccccagcta aaaatccgct gaatgcatgt
     3541 agaaaagtat cccacattga aaaatagcca taaaaatcac ttaactctcc taaaactgtt
     3601 gaactaaaaa taaaagataa caaaatgatt tctagcatat ttggaatctg tatctttaat
     3661 atcttttcca gaaaataagg gatttcaaat aaaattaatg tcagtaataa aagcattgta
     3721 tttccccagt gttggttcca gacctgatcc actagcataa taacgacgat gatacgtaat
     3781 aaaatataga ttccgtttgt gattctacct gcagtttttg tactgttcgt aaaaaaggtt
     3841 ttcaaatgat tcataaaata actccttcat gtatatcctt aattatacta agaagcgtgt
     3901 gtttaccaaa gctatatgac ttaaagaaaa acagagttga tattgtgaaa aaaatcactt
     3961 aatatagtat aaggagaaaa gggggataca aatgaaaaaa ttagttgctg gtttattaac
     4021 agccgttgca cttcttgcta tgagcgcatg cggcgcagat cagaaaaata cagcgcagac
     4081 aagttctagt acgaaggaat ctgccgaagt atcatcaggc gcttctgaac aagtatatac
     4141 agatccaaaa gaaatgaaag aatcttatga tgtcgtgatt attggagctg gtggtgcagg
     4201 gatggcagca gctatcgaag caaaagatgc tgggttgaat ccagtaattt tggaaaagat
     4261 gcctgttgcc ggaggaaaca catctaaatc atcaagcggt atgaatgctt cagaaacaaa
     4321 atttcaaaaa gaagaaggaa tcaaagactc gaatgatgcc ttctatgaag aaacgctaaa
     4381 aggtggtgga ggaacgaatg ataaagaaat gcttcgatac tttgtcgatc actctgctga
     4441 tgcggtcgat tggctagatc aaaacggtat caaactggac aacttaacga tcactggagg
     4501 gatgagtgaa aagaggacac atcgtccgtc tgatggctcg gctattggtg gatacttagt
     4561 ggaggggtta ttgaataacg tccatgagcg ggaaatccct atttttgtca acgcagatgt
     4621 gacagacatt aagaaaaatg gggaaacggt caatgaagtg actgtacatg ttcaaggaga
     4681 agaaccaaaa gaggtcaccg gaaaagcaat cgtagttacc acaggcggtt ttggtgccag
     4741 caaagaattt attgaaaaat atcgtcccga tttagctgat tatattacga caaatcaaga
     4801 aggatcaact ggagatggta tcaccatgat tgaaaaatta ggtggacaaa ccgttgatat
     4861 ggataaaata caaattcatc caactgtgca gcaggatgag ggggtcttga ttggtgaggt
     4921 tgttcgcgga gaaggagcaa tcttggtcga tcaagagggg aaaagatttg tcaatgaaat
     4981 ggatacaagg gataaagtat ctgcagcaat tacagcattg cctgaaaaat cagcttattt
     5041 gatttttgac caaggcgtgc gtgatcgtgc cacagctatt gaattttatg accaaaaagg
     5101 atatgtcaca actggaaaga caatggaaga attagcagaa aaaatcgatt taccaaaaga
     5161 aacactagca aaaacagttg atggatggaa tacggatgtt gcggagaaaa aagatgctca
     5221 attcaaccgt gccacagcca tggaacatga cttatcgtct ccgaattatt atgcgatcaa
     5281 aatcgcacca ggaatccatt acacgatggg cggtgtgaaa atcaatacga acactgaagt
     5341 attagataaa gaaaaccagc caattagggg gttatatgct gctggtgaag tcacaggtgg
     5401 cttacatgga aacaaccgga tcggtggaaa ttcagttgcg gagatcatta tttttgggcg
     5461 acaagcgggc atacaagcag ctcgatttgc ttcggaaaat gaatgaaata gaacgtaaat
     5521 aaaaagaggt tgtgaaatca gcgttttgag ctaataccga gggtcagctg attgaacact
     5581 gtttagtgaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac agccaagtaa
     5641 aaacagcttc ttatgttttt aacttggttg gacttattac cgcagatgca agcttttgaa
     5701 caccgtttat tcggaaaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc
     5761 taaacacgta taaacggcgg aagcagaaga aattccttcg gaaataagct gaaattcaca
     5821 aaaatttgaa aagcaatttt cgtgaatttc ttcttatttc ttggagttaa acgcttctgt
     5881 cccagcctct tttttgatca gcatgatttt attcagttat cttcaaaatg atttttccga
     5941 tgtttttgtt tgcttccata tattcatgcg cttgtttgac tgcgctgaat tggaatgtac
     6001 ggtcaatgat tggccgaatc ttgccatttt ctagaaaagg cccagctttt tgcataaaag
     6061 tttgtgcgag ctctgcttta tactgatcac ttctaggtgt caataatgta ccaagcagtt
     6121 ggacacgttt cccaatcaat acaccaaggt ctatctcagg cacgatggtc ccacctagca
     6181 taccaatcaa gacccaacgt ccatcaacgg ctatagaagc taaattcttt tcccagtaag
     6241 aagcgccgat gaaatccaaa ataacatcga ctccccgacc ttcagtgatt tttcgtacct
     6301 cttcttgaaa gtcttgtttt ttatagttga tcaattcatc tgcaccaagt tctttacaaa
     6361 aggcgagttt ttcttctgat cctgcagtaa cgatgatttt cgcgtgagaa agctgtctag
     6421 ctaattggat cgctgctgtt cccacaccac ttgctcctgc atggatcaag acagtttcgc
     6481 cttcttgtaa ttttccaagc cagtaaagtg tttgataagc agtcaaaaaa acttctgaga
     6541 ttccagcagc agaaacatag tctagcgtat cagggagaag gattgcacga tcggcaggca
     6601 tcacagcata ttcggcataa ccacctagat tgactaatcc gtatactttt gtcccaggag
     6661 taaaagtgga gatatcactt ttattctcaa ctacctctcc agctacttcg actcccaaaa
     6721 tagggtaggg aggtttcaaa gagactgatt ctcttttcat aatatctgtt cgattgacag
     6781 ctgctgtatg gactttgatc agtaattcgc cttgttttgg tttaggaaca ggcacttcaa
     6841 tttgttctaa tacatctaca gaaccaggat gcttgattga aatggcacgc atggatctat
     6901 tcctcctttg cccattcttg gaatgctgta ttcaactctt tgctaccttc agaaagtact
     6961 agagtcgtac gagaaatatc cgtttcttcc actagagcgg caagtacagc agcaactgta
     7021 gagcgagtga tcgtttttga tgccttctca ttaggcttag ttaattgaat ggaagtaact
     7081 tcttcatcgt tagtcaatgt gactggttga agaatgacaa aatctaagtt agttcgtttc
     7141 agccattcat ctgcataatg tttagtaata taataatctg tcatggactc aggccatttt
     7201 gctggttcat ctgcataaac agcactgacc atcagatagc gagagacatg cgcattttca
     7261 gctgcgatca ctgttttgat tgcgccatcc aagtctactt gcagaagatt ctttccttga
     7321 gagccggcag caaaaatcaa tacatcgatg cctttgaatg cttcggtcat tttttccacg
     7381 gaccaagtta aatcaaaaga gacatacgaa acattctctt tttttactaa tgtttgggaa
     7441 gcaacatctc tcacccctgc aaaaatttca tgggaacttg gagctaaatc ttttatcagg
     7501 tgtcggccaa tttgtccgtt tgcacctaca acaaaaattt tcatttggat catcctttcg
     7561 acgtcaaatc tttccattca atagtaacac caaaagagaa aaaaatcaga gatcggctac
     7621 gatgactatc agttagtaag agaagggtgc ttgaagtatc ttaacaagac attgcatact
     7681 gctgcagtcg caagacctgc gacgattcct tcaggtatac cacttgtaaa aataaccgct
     7741 agaatagctg aataaacagc atttaaattt gttccgatga ctttggcata atcttgctgg
     7801 aataaaaagt agatcatatt catcactaaa atcgtattgg tcaatgaacc ggaaagtcca
     7861 gctaagaata aagaaacgga atctgctttt tgtttcatta gtttgcgcag acctttataa
     7921 acgaaataag gaaccacccc aatcaagatg cgaggaataa acgcgatcag caaggctttc
     7981 cagcttccat gttctgttcc gatgactggg ataaacggag aaaagacaaa agacaaaggt
     8041 gtttggataa ctgtgctacg gatcatgctg atcagtccaa atgtaccgcc aagaaaagca
     8101 cctagtcttg gtcctaaaac gatcgaagca atgattacag gaatatgcat ggttgttgca
     8161 ttgattggac cgatagggat aaaacctaaa ggcgtaacag ctaataaaat caaaatagct
     8221 aaaaacatcg cagttaatgt aaagtttttt gtatttttca taagtactcc ttttttctaa
     8281 gcatttcttt cattaagagt cagcatgacc tgttcgatga tcgtctgaat atcagctaag
     8341 gcaccttttc caaaatctcc acaagctaaa agagattctc ttggttcaat ttcctgatag
     8401 ccgacagatc tcaatgtttc cagattacgc tgagtgatcg ggttttgata catattcgtg
     8461 ttcatggcag gggcaatcaa ttttggtgtt cccactggaa gcgccattgc gactgttgaa
     8521 agaagatcgt ctgcaatgcc gtttgctagc ttgccgataa tgtttgctgt agcaggcgcg
     8581 atgagaaaca agtcagcttg ttttgctagt tcgatatgat tgattacctg cggatttgat
     8641 tcttgcatga cgtctgtatg gactgcgcgc ttcgacagag attgcaaggt taatggcgtg
     8701 ataaaatgtg tgctgctttt agacataatc acatctacct gggcacctaa tttgacgaat
     8761 tgacttgtaa gatcagcgct tttgtaagca gaaatacttc cagtaacgcc tagtaagatc
     8821 tttttcattt tgattcctcc agtctaattt tctcagtaat caatgcagca atctcagatt
     8881 tactttgagc ttcttccact gttccatctt tagataagag atagccgtgg tgtgtctcgc
     8941 catggatttc cgtcaaatca tttgcgaaaa taaaatcagt tttgttattt atcagactat
     9001 tttttgcgac tgccagaaga gattcctttg gtacatctac taatagtttg aaaccaatga
     9061 tttttgcttt tggctgccat tcacgtagat aagaaatgat ttttggtgtt ttcttcaaaa
     9121 cgagcacaag atgctcggtg ttagaagaga tctttgaaac agtggtatct gtctgttcat
     9181 tttccgcaaa ccaattgtcc agttcttctt gcgttgaaga agtgggtagg ttttttgcca
     9241 gctgttcttc tgaaaaacta aaagcaggag taaaatcact gactgccata ctgtggataa
     9301 tcgcatcgta gtgttctttt ttcgttagtt cttctaattg taaaaataag tccagtgcag
     9361 attcgatcgt ataaatcgtt atattggagt gtcttttcgg tttcagtgct tgtttcgtag
     9421 tcacgtaatc gattgtggta tccggattgg cagctaaata atcagctaat gcttgcccta
     9481 atcgtcctgt cgaatgattt gtaatagcac gtacttgatc gattttttca gtcgttcctc
     9541 cagctgtgat tagaatcttc atttatggtc acctacattt actagtgttc ttccttggtg
     9601 tgttccagca agtagtttag atgctgtttc aggcaattga tccagagtaa tctcttggac
     9661 gaccagttca tctgcaatct gcaaatccgc catctgttgc cataaagaaa gacgttgatc
     9721 tattggtaca ttgacagaat caattccaat caactggatg tttcgcagaa taaaaggcaa
     9781 gacagtcgcg tttagtttga ttcccccagc attgccacat aaagctactg caccgttata
     9841 agagatcaat ggaagaagac tgcttagctg ctcgccacct actgtgtcga tgacatagtc
     9901 gatttgctgt tttcctaaag cttttgttgt ctctggcaga aattcatcag gtcgtacgac
     9961 ttgcaaagca cctagacttt ttagccatgt gacagactct tcttttctgg aaaaggcaat
    10021 gattgactgg aatcctagtt tatgtaacag ggctatcgct gtactgccta caccgccaga
    10081 agcaccagta acgacaactt ttttatcgga ggtcatacct tgacggatta aagcgttcac
    10141 acacaacata gcagtaaacc ctgctgtacc aaggatcatc gcttgacgca gcgtcatatt
    10201 ttttggtaga ggaactaacc agtctcctgg tactttttga tattggctat aaccgcctgg
    10261 atgggtgacg ccaagcccaa aaccagtagc aagtacaaga tcttcttttg aaaaacgtgg
    10321 attgttactt tggacgacag ttccggataa atcaatccct ggagtcatcg gatatgttcg
    10381 tatcacctga ccagactcgc tcattgccaa tgcatcttta taattgacat cagaataggc
    10441 aatttttacc aagacttcat tttcagccaa ctcagtaaat ggcagatcac tgattgctgt
    10501 atggaaaaca ggttccttta ttacctgaaa agatcgaaaa gcgttcattc gtgagacact
    10561 ccttttaaaa ttttctttta tcataccata aagcctactc ttttattctt gttcttccgt
    10621 aaatttagac aaaaattagg tgaaaaataa agaatcaaac aactagaatt tattccaaaa
    10681 gataaagaaa tattcagcaa aaaaaatttt acaaagggtt gcctttttca ataaatttcg
    10741 tatactaata cgagtggtag taaacaggaa gtttactatt agaaaacttc gattcggagg
    10801 aaattatgga aattggtgag aagttaagaa atttgcgcat ccaaaagaat ttgacacaag
    10861 aagaactagg cgaacgcaca gatttgtcaa aagggtatat ttcccagttg gaacgagatt
    10921 taagttcacc atcaatggaa acattctttt ctattcttga agtcttaggt gtgactccag
    10981 aagaattttt tcatcaagaa gcagcgaatc tgcaagtggt ttattcaaaa gaagatcata
    11041 cggtttattt cgatgaagaa aacgggtatg aattggaatg gctcgtggct gattcgaatg
    11101 aaaaagaaat ggagcctgtc ttgctgactt ttgaaggtgc aggagaatat aagacgtttg
    11161 aaccttcatt atctgaaacg tttatttttg tattagaagg ggaattagag ttaagcttag
    11221 gagagacggt ctatgtggca aaagcaggac agtcgatcta ttatcaagcg acaaaacaac
    11281 atcaattaag gaatcatctc aaaaaacgaa caaaagtatt gattgttgca acgcaatcat
    11341 atttgtaata tagggggtaa aaacgtgggg aaaccaatca tttcatttga tcaagtagtg
    11401 aaacgctatg atgatgaaac agtattaaaa aaagtaagtt ttgagatcga acaaggaaaa
    11461 ttttatacac tgcttggtcc ttccggctgt ggtaaaacaa cgatcctacg tattatagct
    11521 ggattcaccg aagctacaga aggggacatc tattttgaag ggaaacggtt gaatgatttg
    11581 ccagctaata agcgacaagt aaatacagtc ttccaagatt atgcactttt tcctcatatg
    11641 aatgtttttg ataacgttgc ttttggattg aagatcaaga aaatgtccaa atcagatatc
    11701 gaaaagaagg taaaagatgc tttgcgtatg gtccagcttc ctggatacga aaaacgggag
    11761 attagtgaaa tgtctggtgg tcaaagacag cgtgtagcga ttgcacgagc aattgtaaat
    11821 gaaccgaaag tattgctatt agatgaaccg ttatcggcgc ttgatttgaa actacgtaca
    11881 gatatgcagt atgaactgcg ggatctgcaa caacgattag gaatcacgtt tatttttgtt
    11941 actcatgacc aagaagaagc gttggcaatg agtgatgaga tttttgtcat gaataaaggg
    12001 aaaatcgtcc aaagtggtac acccgtagat atttatgatg agccaatcaa tcatttcgtt
    12061 gctgattttg ttggggagag caatatcgtg gacggtgtaa tgatcgaaga taatctagtt
    12121 gagtttgttg gtaagcaatt tgaatgtgtc gatggcggga tgcgtctaaa tgaaccagtt
    12181 gaagttgttt tacgcccaga ggatttgacg atcacgacac cagataaagg aaaactagtc
    12241 gtaacggtcg atactcagct gtttcgtggt gtccattatg aaatcatctg ttatgatgaa
    12301 cagcaaaatg aatggatggt ccattcaacg aaaaaagcta aagaaggaag caaagtagga
    12361 ttggcctttg agccagaaga tatccatgtc atgcgtttca acgagtctga agaagaattc
    12421 gatgcacgtc ttgacagcta cgaagaatag gggggacaag aatgaaaaca atgcgcagga
    12481 tctattccgt cccttatatt ttgtggctcg gtttattcgt gatcgcgcct gtattaatga
    12541 tcatttatca atcttttttt gatatgaatg ggcaattcac gctgaataat tatctatctt
    12601 attttacgtc ggggacatcg ctttctatga cgatcaattc tgtatggtat gcatttttga
    12661 tcacgttttt cacgctgatc atcagttacc cgactgctta ttttttaaca aaactgaagc
    12721 acaagcaatt atggctgatg ctgattattt tgcctacatg ggtgaatctg ctgcttaaag
    12781 cttacgcatt tattgggatt ttcagtgtgc acggcagcgt gaatcatttc tttgatttta
    12841 tcgggatcgg gccgaaacag atattattca cagacttcag ttttctgttc gtggcaacgt
    12901 atatcgagat tccatttatg attatgccaa ttttcaatgc attggaagag atgaatcctt
    12961 ctttgatcag tgctagtaga gatttaggcg cgaatagctt tgagaccttc cgacgagtga
    13021 tttttccgtt atcattaaat ggtgtgaaaa gtggtgtcca agcagtattt attccttctc
    13081 tttctttatt catgctgact cgtctgattg gcggaaatcg ggtgatcact ttaggaacgg
    13141 ctatcgaaca gcatttcttg gttacacaaa actgggggat gggttctaca atcggtgtga
    13201 ttttaatcat tgctatgttc atcgtgatgc tcctgacagg cgagaagaaa aaaggaggtc
    13261 gctcataaat gaaaaaattt aaatggtcgt atctttattt agggatcgtc tttttattct
    13321 tatatgcacc gatcttctat ctgatttttt attccttcaa tgaaggagga acgatgaaca
    13381 gctttacagg atttacttgg gaaaattatg aagctgtttt tgaagataca cgtttgatca
    13441 ttatcgtatt gaatacgttc atgctggctt tcttatctgc attgatcgcc acgatcatcg
    13501 ggacatttgg ggctatggga atctattaca cgaaaaaacg acgtgcacgg acagcgttgt
    13561 tgagcatgaa taacatctta ttagtctctc ctgatgttat tatcggtgct agtttcttga
    13621 ttttctttac actactagga ttcggattag gttttcagag tgtattgctt tcccatattg
    13681 ctttcagcat tccaatcgtc gtcttgatgg tcttgccaaa attgcaggaa atgaacgatt
    13741 caatggtcga tgcggctaga gaccttggtg ctaataattt ccaagtagtc aaaaatatca
    13801 ttttgcctta tctttctcca ggaatcatag ctggatattt tatggcattt acctattctc
    13861 ttgatgattt tgcggttaca tttttcgtca caggaaatgg ctttacgacg ctctcagtag
    13921 agatctattc tcgtgcaaga caaggaatca gtttagaaat caatgcgcta agtgcgttag
    13981 ttttcttgtt ctccatgata ttggtcattg gatactactt tattagtaaa gaaaaccgtc
    14041 caaaacggct gaagaaaaac agaagagtac gcgagggggt ggcacggctg cgatgaaaaa
    14101 attacaatct ctgtttttag gtattctcat cattattgcg gtgctgctgc ttggtgttcg
    14161 tcaacttgaa aaaacaagtg gcatgagtgg agcaaaggta cttaccatct ataactgggg
    14221 agattatatc gatcctagtt tgatcacgaa atttgaaaaa gaatatggat acaaagtgaa
    14281 ttatgaaaca tttgattcta atgaagcgat gttcacaaaa atccagcaag gtgggacaaa
    14341 ctacgacatc gctataccaa gtgaatatat gatccaaaaa atgatcaaag aaaaactagt
    14401 acttccatta gatcattcga agatcaaagg attaaataat attgatccac gatttttaga
    14461 cttggatttt gatccagata atcagtattc gattccatat ttttggggaa ctttagggat
    14521 cgtatataac gataaattct ttgatgcaaa tcaaattaag cattgggatg atttgtggaa
    14581 gccggaatta aaagacagtt tgatgctgat tgacggtgca cgagaagtta tggggctttc
    14641 tttgaatagt ttaggctatt ctttgaatag taagaatatg gcacagctga cagaagcagc
    14701 aaataaattg aatcatttaa caccaaatgt caaagcaatc gtggcagatg agatcaaaat
    14761 gtatatgatc aatgaagaag cctccgtggc agtgacattt tctggcgaag ctgccgatat
    14821 gatgtgggaa aatgaacatt tacattatgt gatcccacca gaaggatcca atctttggtt
    14881 tgataatatc gttatgccaa aaaccgtgaa aaataaagaa ggtgcctatg atttcatcaa
    14941 ctttatgcta gaaccggaaa atgcggcaca aaatgcagag tatattggtt attctacacc
    15001 aaatgaagaa gcaaaagcgt tattgccaaa agacatttcg tcggacgaac aattctatcc
    15061 atctgatgac acgatctccc atcttgaagt ctacaaagat ctaggatcga aatacctagg
    15121 catctataat gacctattct tagaattcaa gatgtatagg agataatggc aaaactcagt
    15181 aagaatgggg acttatcaac gttctaaaga gctaaaaatc gtcctttttc tatctgagtt
    15241 ttccaatctt ctaccaaaag cggatgaaac gccgcttttt ttgtgttatt ttattttttc
    15301 taccacgttt ttctaccaga gaaaagtgga caaaaccatt gtaaaatagg gcccgagacg
    15361 ggctagtaaa tctaagattg aaaaagttac agaaggataa agtaattgga aactatgcaa
    15421 atatacttaa cccttctgta atctattaat aaaactaata tatgaatcca gttcaatatt
    15481 tgtagctatg aaaaaacata aaaatcatat tagataaaaa ctaaattggt agataaatta
    15541 ttttgtcaga tatctgaggc aaatattcga ctatttgtgt ttcaaagtaa aaattggaat
    15601 acaaatatag aatagacata ttgcagccga tagtttatta tgcttttaga cacattaaac
    15661 tggaggaaaa aatgaaaaag agcgctaaag atcgagtttt tgatgagctg atacgactaa
    15721 cagggaatat gtcttctgtc actgccgaga aaatttcgaa gaatctaggt atctctcgtc
    15781 agaatgccag ccattatttg acgagattag tggaagataa aaaggtcgag aaattaccgg
    15841 gaaagcctgt tttgtggaag cctttagatg aatatgcggt tgtagataat acggagcaaa
    15901 taaacgaagc ctttcattct gtagttggtc atgacggaag tctgagagag gtcattcaaa
    15961 aatgtatagc cgctgtcaaa tatccgccta acggactcag tgtattaata aatggagcca
    16021 cgggtgttgg aaaaagtttt ttagccacaa aaatttttga atacgctatc catgagcaaa
    16081 ttattgaaaa agatgcacca tttgctatct taaactgtgc cgattatgcg gacaatcccg
    16141 aactgctttc ggcaacactg tttggataca agaagggggc ctttacgggg gctgaaaagg
    16201 ataccgatgg tttattggca acggccaaca acggctatct ttttctcgat gaggtccatc
    16261 gcctatcgaa agaaaatcaa gaaaagctct ttctatttat tgatactgga aactatcgtc
    16321 cagtcggtga aaatgtaaat tggcattctg ctaaggttcg ttttattttc gccacgacgg
    16381 aaaaaggtga aaattattta ttagacacct ttgatcggcg tattcaaatt agtgttatgt
    16441 tgccaacttt tgaagatcgc cccattcgag aacgattaga gctgattcaa ttattttttc
    16501 aaaatgaagc ggatgtttta caaaaagata ttattgtttc aagagaagcc ttgtctttaa
    16561 tgttatctca tccctttagt gggaatattg gtaagctgaa gaatatcatt aaaatcagtt
    16621 gtgcggatgt gtatagtcga acacaagaag aaccattaac gattgggaaa aatgagatct
    16681 tgattcagtt aaatatgctg gaatccgaag tagaaagctt gccgattgct agtttattga
    16741 taaagaaaaa tcaaaagata aaaacggatc gaatcaaacc gtttgattat gattcgattt
    16801 tggaaaaaat tactcagctg ataaatgaag gtaatttcaa tgaaaatttt tcttcgataa
    16861 agaatgaagt acagcatttg gtgcatcaca ttgataagga ttctttttta tcaatgagta
    16921 gaaaattgat gattcagatg tttagaaagg tctgggtatc cgttttagga aaaacgtacg
    16981 gattgacgac gagtggacct gttgcagaaa ttattagcag atcctatgtc atttccccaa
    17041 gctataagac agacttaacc gggataaatc gtacattagc tgcaaatcta cctcggacga
    17101 cttacttatg taatcagttc ttggagcatt taccaccgct ctcagaaaag gacgagaact
    17161 ttctaagact gcttattgtc gtgactttat ctgattatgt agatgaatcc atcgagctga
    17221 agggcctgtt gcttgctcac ggagatagta cggctagcag cattcaagca gtagtgaatc
    17281 aattatgcgg caattatgtt tttgaagcgt tggatatgcc agtagagagt aatgtgtcag
    17341 agattgtcga atcgacaagg aatttcgtga aacggcaagt gaatacagat agtctagtgc
    17401 tgatcgtaga tatgggctct ttaaatcaaa tttacacaca gatcaagaac gatttaaaag
    17461 gggagttact tcttctgaat aatttgacga cttccattgc acttgatatt ggcttgaaga
    17521 tgacgatgaa tgcgccattt aaacagattg cggaggatgc agcagacaag tattcaatca
    17581 atgttcaata ctttgaaggc ttttctcaaa gtagcaacat tatcatttcc tgtatgtcgg
    17641 gtttggggat ttcggacaaa ttgaaagatg tttttcgtca tcatttatcg gatgaatcca
    17701 tcgaagtttt cacgaaggac tacagagaac tacgtgaatt aatcgaccaa aatgatgaaa
    17761 cttattttga caagacaaaa ttggtcatca cgacttcgga tcttccacgt tccttttcaa
    17821 ttcctaatat taatgtttat gacatcttag acggtgatgg agcagccaat ttggagcata
    17881 ttttgagtcc tgaaatgaag ccggcagaat ttaaccgctt gattcaggag ctagtaaaat
    17941 tcttttcgtt ggaaggaatt gcggaccgtt tgaactttct gaacccaacg atcgtgatga
    18001 gtgaagtgga aacagtcatt tctaaatatg aaaattacta tcatttcact ttaaatggcc
    18061 gtgtaaaact aaatctctat atgcatacgg cattgatgat ggaacgttta ttcttggctc
    18121 ggacagaaaa atctgaagaa ccgaattatg atttgaaacc agatgaagat gaattttatt
    18181 atgtttctag aagtattttt caatcaatgg agatgaaata taattttaaa gtcaatgctt
    18241 atgagctttc gctgctctat gaattattag gaccgtatat tcaaaaataa agtgtctaaa
    18301 aaagtgtcta atctgttttt tttaggttag acactttttt taatgtgaat taacgtgatt
    18361 aaaccaatgt ttttaaaagt tggcacagga attgcttata taaaagtgaa cagaaagaaa
    18421 ggaattaacc atatgaagaa aattctaata gcgactcacg gtcacttagc ttcaggcttt
    18481 cttagcagta ttcaattact gacggggaag gttcaagaga ttacggtgat taatgcttat
    18541 gtggatgagt gtgattttga acaggagttg aatgtatttg taaaccaggt gaacgagcag
    18601 gatcagattt ttgtttttac cgatttattt ggcggaagtg tcaatcagaa gattaccaaa
    18661 acctttttgg agaaagagat tgctgtaact attttgtctg gctttaatct gccaattctg
    18721 ctcgaaatag tattggcaac caaggaatta acaaaggagg atattcagga actggtaaat
    18781 aaatgccaac aggaattaaa gatgaccatt cttgatgagg tacatgtagt aaatgaagag
    18841 gaagattttt tttaggagga agaaaaatga ttaaagcagt gcgaattgat gaacgattaa
    18901 ttcatggaca agtagcgatg acttggacaa agagtctaaa tttaaccggg ttagtagtag
    18961 caagcgatga ggcggctacc aacgatattc aaaagatgac attgaagatg gctgcaccat
    19021 cgaatgtcaa agtcattatt aaaacagttg atgacgcgat tcatttgtta aaagatccgc
    19081 gggcgaagga catgcgcttg atggttttag tccctaatgt caaagatgcg gtaaaagttg
    19141 cgaaagcttt cccaacggaa atcgaattaa tgaacgtggg gaatgctggg aaaatgacac
    19201 cgccatcgga agataagaaa accttatcaa aggaagtgat gttaacgacg tcagaaattc
    19261 aagacttaaa agaattagtt gaactttatc cagataccgt ttttcagcct acaccggcga
    19321 tggaaaaacg ttcagctatc tctattttga gtgattttta gaaaaaggaa ggagaaaaat
    19381 tatgtatgat gcatttgtag tcgctttggc cgtttttatt ggagttgctg gacatgaaat
    19441 gttcgggatg tccatgctga gtcgtccgat tgttgttgct ccgttagcag gagcgttgat
    19501 gggggatttg cagacggggt tgattgtcgg ggcgtcacta gaagccatct ttatgggtgt
    19561 cgtcaatatc ggaatctcta gtacggcgga gccttctttg gctgctgggc tggctacagc
    19621 gttcgcaatc aaaatgggag gaaacgtgga tgcgattatt cccattgtct ttccactagc
    19681 agtattagga ttacagttaa tgaatatgat tttttctttt gtatgtggac cgatggctgc
    19741 taaatttttc aaatttgcaa aatctggtga tcaaaaagga atcatcaatc tgcacttctt
    19801 tatgtggttt gtccactatg cgctttatgc tcttattcca ttctttgccg ttttatttgg
    19861 agcagatgtt gtcaaaagcg tcttggataa tattccagag gtcatcatga acggattaac
    19921 agtcgctgga aatctgctgc cggcagttgg gatggcgatg ctgttacgga tgctttggag
    19981 taaaaatatt gctgtgtggt ttttctttgg ggccgttgtt atggcgtatc tcgagttacc
    20041 attgattgca attgccgcag ttggaacgat tattgcaatt gttatagccc aaagagatct
    20101 acaactaaaa aatatatctg ttcatgcagt tcaaagcgat gctgctgtaa atgcaacgct
    20161 tgaccaagaa gaggaggatt tctttcaatg aaattagctg atggaatttc taaagatgag
    20221 aaaaaattgg ttcggaagat gttttggcgc tcgatgacta tgtatgcttc ggtgaatccg
    20281 gtgacgatgg gcggcggtgg tttcgcctat tctatgatgc ccttcattaa tcatttctac
    20341 aaaagtgaag aagatcgagc tgcggcgctg gaacgtcata cacagtattt ttcgacgacc
    20401 attccttgcg cgtcctttgt catggggatt gcggcatcga tggagaagga aaattctgaa
    20461 aaagctggtt ttgacgtgga aagtatcaac gcgatcaaaa cgagtttgat gggaccattg
    20521 gctggaattg gcgattcatt gttctgggga gtttggcgtg tcgttaccgc gggactagcg
    20581 atcaacttag ccaatgccgg aaatattttg gcaccaatta tctttttagt tatgttcaat
    20641 atacctaatt acttgatgcg atactatggc ggcgttttag gctattcatt aggctctaaa
    20701 tatattgaaa agctgtatgc gaacgggtta attgaaattc tgacaaaagc tgctagtatc
    20761 ttgggtctga tcatggtagg tgcaatgacg atcagtatgg tcaaattcaa taccgttttg
    20821 agcttttcaa tgaagggcga agaactaatg aatgtccaag aaatcctcga tagtattttt
    20881 aaaggaattg taccgttatt ggtaacattg agctgtttca aattactaga taaaaaagtc
    20941 ggcgtcatca aaattatttt tggaatggtc gtcttgggaa ttttattgtc attacttgga
    21001 atcgcatagt aggaagctgc agctactagg ctgcagtttt tttagcaagg agggaaaaga
    21061 tgactattaa tgaagtaatt tattcaccca aacacccatt ttttaatgct gagttaaacg
    21121 acggaaatgt gactacttca aacgaataca gctactatcg gaatattcct gatgtaaagg
    21181 gattgacctt cgatgtaagt aatcaaaaga cattagcaaa ccttgatgtt tgcgggacga
    21241 ttcaaacgtt gaccttttat cgagaaaatt tactaactga ggaaaaacca ggtgtttggg
    21301 tcaataaaca gctctctcaa accaattcgt tatccttaaa ggttgaagta aacgggattg
    21361 tctaccattt gtcagaatcg gatcatcgta ttgaagtcga tgtgattcaa gactgtttgc
    21421 ctagatatat tcatcattat tcgacgttta aggtcattgt agtatccttt gctcccatac
    21481 tggctaataa gcgtttaagt atgcttgttc aacaggttta cattgtgaat gaaacacacg
    21541 aaagccttca agtttcagtg aaagatgtgc cttcgtatca agagaagtat tcggatcagc
    21601 aaaatgtgtt gatttctcaa aaaggaaata aggacacgat cgcacaacag gaagtggcaa
    21661 gcttcgccat tgcttttgtg gacccaaatg cttttgaaga agtaatgact tttcaggaat
    21721 ctgatatcga aaaatggctg aaggaaacat tgaactattt tgctcagcta tttgggcagc
    21781 tgtcaatgcc aaacgataga gttgtccatc tctatcgtcg tgcactttat caaagctttt
    21841 ctagtttcgg tatgaatcga cagggacagg tcgtcggcag caattggggc agctatcctg
    21901 ctactaatcg aatttggaat aaggatatgt attacgcatc attgccattc accatgtttg
    21961 aaccggagtt atgtcaaaaa acggttctat ggtttgatca atatggcgtt aagtttcctg
    22021 gttcaaaatt tacaggaggt atcaatcatt ctctgagtaa ttcgttatcc agtgcgttac
    22081 tggctagtct ttattttgaa catactgggg atacaaaatt ctttgagcgg tgtccgcagg
    22141 ttctactgaa tgcttcaaga attattgagg acatattagc tcaacgtcgg tcaggggaac
    22201 caatgctttt tccatctgtt tggttatcag acgcctttgc acttggaaag tatcataccg
    22261 gcagcaatct ttgtctttgg aaggcctgta ttggacttgc agaaattttt gaagccctag
    22321 aacaactgag tcttagcaag cgatacaaaa acattgcctg taaactaaag gaatcaattt
    22381 gtaaacaaat gactatcgat ggtccttttg gtgagcaatt tttggaggga atcggtgatg
    22441 aggagaaaac aacctattca gtgaagcact atcaaaaacc gattcttgag caagggttaa
    22501 tctttttaag tgatgtgatt gtggatggaa aaattaattt attgatgcat gatggagaag
    22561 aatcagacac tacgttgatg cctttttatc aatttttaga taataaagat catttatatc
    22621 agaacaccat ggccttttct gctagttctt tcaatccaac ctatagcgag gaaatcaaag
    22681 gcatcacttg gggattagaa tccggcgcca cttttcctgg ctttatcact gttttaatga
    22741 gcgagctgca caaccctcaa gctttcgtaa cccgattaga agaactaatt tgtttggcag
    22801 atttagacgg ttcgtggtgg tggtggccgt atcgcttaga ggctcaacaa ggagaagtcg
    22861 tgcgagactt tggctgcggc aaatgcggct gggcatcggg tctttttgtc agcctaatga
    22921 tcagtcaata tttcggattg aaattcaaaa aaggagtatt gcaaattgat cctgttgata
    22981 atttaacgtt ttcttggaag aatttgaagt tcggtcaagc cttcatttcg attgaatgta
    23041 cgcaatccga gttgagtatt tcaaatttgt cagaaaagcc attgaaaata agtgatacga
    23101 aaaaaattct tcacgtagaa aagggaaaaa cgattcacat tcaaaggaga aaaagatgag
    23161 tatactaaaa aatattaccc aatttaaaaa aatccagagt cgagcaatca ctcccgaaaa
    23221 tccaacaggc gagaaaggta aagctgcgat gttgccaagc gagctaggac caagccgcaa
    23281 aggtcgtggc gcaattccgc tgacttctgg tgaagaaact gtgattgcgg atattactgg
    23341 aacgggaata attcgtcata tgtggatgac gattcgtgat cgaacagaat ttggcagttt
    23401 tgttttacgt gatttaatct taagaattta ttgggatggg tcggatagcc ctgctgttga
    23461 aagtccttta ggggatttct tttgtaatgg gtttggagag cgttgcgagg tgaactcgtt
    23521 gccgatagtg gttaatccta cagggggctt taattcctat ttcgaaatgc ctttccaaac
    23581 atccgctaaa attacgatcg agaatttaca tccgaaggat atgtcctcat ttttttatac
    23641 gataaattac gctttggtgg acgaattgga agaaaatagc ctatattttc acgcaaattg
    23701 gcatcgggaa cgcattacca aattacagga ggattataag ttaattgatc gattaaaggg
    23761 tcaaggctat tacgtgggta cttaccttgc gcttacctgc ctagaacgtt attggtgggg
    23821 cgaaggcgag tttaaattct acattgatgg ggatagtgag tatccgaccg taacctcaac
    23881 aggttcagaa gattattttg gcggggcgtg ggcctttcat gagtacgatg agttcggacg
    23941 tccacatgcg aaaaactatt caacagcctt tttagggtat ccttaccaat caaatagaga
    24001 tgccacaaga gatcgttttg aaacgggaaa attgaatgcc gttcatgcct ttggtgacga
    24061 cgcaatgcca cgacatggtc tttatcgttg gcatcttcaa gaccccatct gttttaccga
    24121 agatttatcg gtcactttac aacaaatcgg caacgatgat gttcgcttat ttgagcggca
    24181 agacgatgtt gctagtgtcg cttactggta ttcaacagaa gcttcaggaa atactaaacg
    24241 tcatttcact gatcgagaac gcttgccgcg ttaatgaagt gtttttcaca tattcgaagg
    24301 gaggaaccta tgatgatata tggggcaatt gaagctggag ggactaaatt tgtctgtgca
    24361 gtcggtactg aggaattaac gattttggaa agagtcagtt ttcccacaac aactccagtt
    24421 gaaacaatga agcaggtcat tgattttttt aaacctttta aggaacaatt ggcaggcatc
    24481 ggggtcggct gctttggtcc aattgatatt caatgcaaat caacgagttt cggtcatatc
    24541 acatcaacac caaaacttgc ttggcaaaat ttcaattttg taggaacgct aaagcaatat
    24601 ttcaatattc cgattgaatg gacaacagat gtcaatgcgg cttgctatgg tgaatatgtt
    24661 gctggttctg gcaaagggtt agcaggtgtt gcatacttca ctgtgggaac aggtatcgga
    24721 ggtggtgcct tgttcaatgg gactttcgtg gaagggttca gtcatccgga aatggggcat
    24781 atgttgatca agcgacatcc aaaggacaat ttttcaggaa actgtccctt ccaccaagat
    24841 tgtttagagg ggatggcagc aggaccagcg attgaaaaac ggttgggtgt aaaaggccag
    24901 aatttattgg ctgacgattc gttttggcag attgaagcct tttaccttgc ccaatgtgca
    24961 tacaatacaa cactgatgtt ttcgccagat agaattattt ttggcggtgg tgtaatgaaa
    25021 caagaacaca tgaagaaaaa agttcaggat aaatttgttg agcttataaa tggatatgtt
    25081 gaaataccac caattgatag ctacattatt acgcccgaat taggtgataa tgccggaata
    25141 atcggcggat tagcattggc cagaaaagcg gtaagaaata agcaaccata attaatgaat
    25201 gtttcattga tactcatgtc aaaagtattt aaccgagtaa tcaaatgatc aaatgaagtt
    25261 ggataaagcg aaaatgaatt caaataaaaa ggctctaagt caaatcgtgt tgttttcatt
    25321 aaatcactga aaggaaatgc ttctgcgttt ccttttttct ttttgttgtg cgctgtatac
    25381 cttgaggata ttcactggtg gcgtacactt aaatagtaat atattgtgtt actttatgtc
    25441 tgtggtaata gttatagttg cttaccaatg tatgttcatt tttcgaaatg ttgacttcat
    25501 aatccttggc ttaatgtttg aatttttttg gtgatagatt ttttcagccg tataaaataa
    25561 atcgtaattc tattatagag agttgtgatt ataaaaagat agcaagaaaa aaaaagaaag
    25621 tttctataca ttttaaatat tttattccta tttctattgc t
//
LOCUS       DAZKCW010000037        25458 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000037 DAZKCW010000000
VERSION     DAZKCW010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.037"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(155..520)
                     /locus_tag="ACG84Z_001752"
     CDS             complement(155..520)
                     /locus_tag="ACG84Z_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162596.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            728..1210
                     /locus_tag="ACG84Z_001753"
     CDS             728..1210
                     /locus_tag="ACG84Z_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162597.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1407..2297
                     /locus_tag="ACG84Z_001754"
     CDS             1407..2297
                     /locus_tag="ACG84Z_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFP9162598.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            2623..5097
                     /locus_tag="ACG84Z_001755"
     CDS             2623..5097
                     /locus_tag="ACG84Z_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFP9162599.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLLKRRNNTVAMTGDGVNDI
                     LAMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLV
                     KNIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNV
                     MEKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKF
                     RSQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLF
                     ERKNEKEQKPFSRVVKKFLSIFKREN"
     gene            complement(5200..6936)
                     /locus_tag="ACG84Z_001756"
     CDS             complement(5200..6936)
                     /locus_tag="ACG84Z_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9162600.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(6933..7637)
                     /locus_tag="ACG84Z_001757"
     CDS             complement(6933..7637)
                     /locus_tag="ACG84Z_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9162601.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            7768..8273
                     /locus_tag="ACG84Z_001758"
                     /pseudo
     CDS             7768..8273
                     /locus_tag="ACG84Z_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
     gene            8233..8571
                     /locus_tag="ACG84Z_001759"
     CDS             8233..8571
                     /locus_tag="ACG84Z_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFP9162602.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            8592..10010
                     /gene="ffh"
                     /locus_tag="ACG84Z_001760"
     CDS             8592..10010
                     /gene="ffh"
                     /locus_tag="ACG84Z_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFP9162603.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDTVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            10122..10700
                     /locus_tag="ACG84Z_001761"
     CDS             10122..10700
                     /locus_tag="ACG84Z_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFP9162604.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            10704..11225
                     /locus_tag="ACG84Z_001762"
     CDS             10704..11225
                     /locus_tag="ACG84Z_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFP9162605.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(11304..11858)
                     /locus_tag="ACG84Z_001763"
     CDS             complement(11304..11858)
                     /locus_tag="ACG84Z_001763"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFP9162606.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            12111..12386
                     /gene="rpsP"
                     /locus_tag="ACG84Z_001764"
     CDS             12111..12386
                     /gene="rpsP"
                     /locus_tag="ACG84Z_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFP9162607.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            12398..12649
                     /locus_tag="ACG84Z_001765"
     CDS             12398..12649
                     /locus_tag="ACG84Z_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFP9162608.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            12773..13564
                     /locus_tag="ACG84Z_001766"
     CDS             12773..13564
                     /locus_tag="ACG84Z_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162609.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            13734..14255
                     /gene="rimM"
                     /locus_tag="ACG84Z_001767"
     CDS             13734..14255
                     /gene="rimM"
                     /locus_tag="ACG84Z_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFP9162610.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14245..15006
                     /gene="trmD"
                     /locus_tag="ACG84Z_001768"
     CDS             14245..15006
                     /gene="trmD"
                     /locus_tag="ACG84Z_001768"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFP9162611.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15142..15489
                     /gene="rplS"
                     /locus_tag="ACG84Z_001769"
     CDS             15142..15489
                     /gene="rplS"
                     /locus_tag="ACG84Z_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFP9162612.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            15799..16041
                     /locus_tag="ACG84Z_001770"
     CDS             15799..16041
                     /locus_tag="ACG84Z_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFP9162613.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(16129..16275)
                     /locus_tag="ACG84Z_001771"
                     /pseudo
     CDS             complement(16129..16275)
                     /locus_tag="ACG84Z_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            16332..16646
                     /locus_tag="ACG84Z_001772"
                     /pseudo
     CDS             16332..16646
                     /locus_tag="ACG84Z_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345994.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
     gene            16675..17934
                     /locus_tag="ACG84Z_001773"
     CDS             16675..17934
                     /locus_tag="ACG84Z_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9162614.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            17987..18883
                     /locus_tag="ACG84Z_001774"
     CDS             17987..18883
                     /locus_tag="ACG84Z_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162615.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            18894..19763
                     /locus_tag="ACG84Z_001775"
     CDS             18894..19763
                     /locus_tag="ACG84Z_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162616.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            19773..20448
                     /locus_tag="ACG84Z_001776"
                     /pseudo
     CDS             19773..20448
                     /locus_tag="ACG84Z_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            20654..22318
                     /gene="alsS"
                     /locus_tag="ACG84Z_001777"
     CDS             20654..22318
                     /gene="alsS"
                     /locus_tag="ACG84Z_001777"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFP9162617.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            22331..23041
                     /gene="budA"
                     /locus_tag="ACG84Z_001778"
     CDS             22331..23041
                     /gene="budA"
                     /locus_tag="ACG84Z_001778"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFP9162618.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            23171..23668
                     /locus_tag="ACG84Z_001779"
     CDS             23171..23668
                     /locus_tag="ACG84Z_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFP9162619.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            23853..24113
                     /locus_tag="ACG84Z_001780"
     CDS             23853..24113
                     /locus_tag="ACG84Z_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162620.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(24475..24714)
                     /locus_tag="ACG84Z_001781"
     CDS             complement(24475..24714)
                     /locus_tag="ACG84Z_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162621.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            25000..25314
                     /locus_tag="ACG84Z_001782"
     CDS             25000..25314
                     /locus_tag="ACG84Z_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162622.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT         8449 a         4306 c         5236 g         7467 t
ORIGIN      
        1 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
       61 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
      121 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
      181 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
      241 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
      301 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
      361 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
      421 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
      481 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
      541 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
      601 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
      661 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
      721 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
      781 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
      841 cctgatccaa ggaagcggat tagtggtttc taggaatttt ccagctttga ctgttttcta
      901 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
      961 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1021 gattatcggc cctaatggtt tgagcgagag tggattgaag gattcagctt attcctccat
     1081 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     1141 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     1201 taactattga tggtggatca tcagtaaaaa agcatatgag ctgcgtaaaa tgcatgtttc
     1261 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     1321 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     1381 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     1441 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     1501 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     1561 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     1621 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     1681 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     1741 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     1801 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     1861 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     1921 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     1981 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2041 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     2101 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     2161 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     2221 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     2281 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     2341 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     2401 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     2461 aaaagagcta cgacatagaa ctgtcgtagc tttttttttg ctatatgaca ggaatgaaag
     2521 gtgtttgcaa gcttaatgtg aggaacactt tccatatctg ttctatactg gataggagaa
     2581 gtttggaaat atccagaaaa cgaaatcaat cgaggtagcc acatgaagaa taaatggata
     2641 aatcgaagta aaaaaaagaa agtaacacaa agatcatcag ataaagtcat ccgtcttttt
     2701 ccatcgtata aagaaggatt aacggcagat caagtcaagg aacgaataga aaaaggtgca
     2761 gcaaataatt cagtcgatcc cacattcaaa acaaatcagc aaatcgtatt ggaaaacata
     2821 tttacgtatt tcaatttgat ctttcttatc ttagccattt tgctttgttt agtagaatcc
     2881 tataagaact tgactttttt accagttatc atagccaata caggaatcgc catttttcag
     2941 gaaattcgat ccaaaaagat cttggacgaa ctaaatgttt taaatacagc aaaagtcaat
     3001 gtcatacgag acgggataga acaaacaata gatatagaag accttgtaat agatgacatt
     3061 gttattttag agactggaca tcaaattcca gcagatgcag aggtcgtgga agggaaactg
     3121 caagttaatg aggctttatt gacaggcgaa gcagatgaaa taaccaaaga aataggcgat
     3181 ccattaatgt ccggcagttt cattgtttcc ggaaaagctt acgcccgatt agacaaagtt
     3241 ggagcagatt cgtatatttc ccagctgaca gtcaaagcca agacaatggg agaaggagaa
     3301 cagtcggaga tgattgcttc tcttaatcaa ttgatcaaat ggattgggat catcattatt
     3361 cctatcggta tcctgctttt ttctcaaagt tactttttta atggaaacac gatcaaagaa
     3421 agtgtcgttg caatggaagc agcattgatc ggtatgatac ctgaaggact gtacttgctg
     3481 acgacgattg cattagcatt aagtgcgact aaactagcaa agcaaagagt tcttttacac
     3541 aatatgaaaa gcattgagac attggcaagg gtaaatgtcc tttgtgtaga taaaacagga
     3601 acgatcacag aaaataaaat gtctgttcaa aaagtgatcg tctctaaaaa acaagaaata
     3661 atcagtcagt cagatcaatt ggaagcatgc attgctgact atgcaaaagc gatggcagga
     3721 gacaatgcaa caatggaagc tgttaaagca tattttacaa aaaccactga tcaatcctat
     3781 caccatgtta ttcctttttc ttctgtccaa aaattcagca gtgtagcgtt ggcagacaag
     3841 gtgtatgttt taggagcgcc cgaaatggtt ttgcgcgatc aattgccgga atatgcggaa
     3901 gagtttgttt ctttcgctga aaaaggctat cgcgtgttgg tctttggtgt gtacgatggg
     3961 attcttgaag aaccagtatt gacagaagca gtcacaccat taggctatat tctgattgct
     4021 aatcctatca gaaaagaagc aagagccaca tttgattact tcaaaaaaca gcaagtagcc
     4081 atcaaagtga tttctggaga taatccgctc accgtatcca atgtagctgt ccaagcaggg
     4141 atttcacatg ctgatcagta cgttgatgca tctaaattat cagaagaaga atatgaagca
     4201 gctgtcgaaa aatatacagt ttttggacgc gtcaagccag aacaaaagaa aatcttcgtt
     4261 caattgctaa agcgtcgtaa caatacagta gctatgacag gtgatggcgt gaatgatatt
     4321 ctagccatga aagaagcaga ctgcagtata gcgatggctt ccggaaatga agccgccatg
     4381 caggcctcac aagtggtctt acttgattct gacttttcac gcatgccaga agttgttgca
     4441 gaaggacggc gcgttgtgaa caatattgag cgatcagcca gcttgttttt agtgaagaat
     4501 attttctcct ttttgctctc actgttttca gtgatctttg ctctgaccta tcctttagaa
     4561 ccatcacaaa tcacattgat tagtttgttt actatcggac ttccatcttt cttgcttgct
     4621 ctagaagaaa acaaaaagcg aatcagaggg aaattcatca tgaatgtgat ggaaaaagct
     4681 gtgccaggtg gactaacaga tatgatcgta gtcggtgcgt tggtgatctg cggggtgact
     4741 ttgaatctaa ataaaacaga tgtttctaca gcatctacca tgcttttgat tgcagtaggg
     4801 ttcctcgttc tctataaaat ctgttcaccg ctgaataaat tcagaagtca gatcattctt
     4861 ttctgtgcta gcggtaactt tttttcggtc atctttttgc ataagctgtt ttcaatcacc
     4921 ggtatctcag ctgtatcact tttgctgttg agcattctat ttttctcggc agattcgatt
     4981 tttaggcatt tgaccacatt ggtagaatat ttgtttgaac gtaaaaatga aaaagagcaa
     5041 aagccgttta gtcgcgtagt taaaaaattt ctatcgatat ttaaacgaga aaattgacga
     5101 aaagtatctc aaaaaagagt aaaaaagaac aaccactcgt gtatctttcg aagcaggatg
     5161 agtcatccaa ctttaaaacg cacgagcagt tgctcttttt tacattttcg gaatggtaac
     5221 ggtgaaagtc gaacctgttc caagatgact gtctacagta atcgtaccat gaaggagttg
     5281 cacgtagtct tttacaatcg ctaaccctaa tccggtcccg cctgaatgcc ggcttcgcgc
     5341 cttgtctacg cggtaaaaac gctcaaagat ccgttcctga tcctcaatgt cgatacctat
     5401 accaaagtct tggacagaaa acgatagatc atctgttgcc tgatagcgga taataatctc
     5461 gctgtcgctt tttgaatatt ggacagcatt ttcaatcaga tttttgataa ttggataaag
     5521 gatatctgtt ttagtagtaa atggttcgtt ctttccaatc aatcgaatcg tcaaccgttt
     5581 cttttcgatg attggctgat aattttgaac gatttgctgg aaataaggtt ctgtataaat
     5641 tgtctggatc tcgtaagaat tctcgccatc ttttgacagc tggatgattt cccgaatcag
     5701 tttatctaac cggatcgcat ctttttgcat gatctcaaga aaagaagtca gagtttgcgg
     5761 gtcatctttt gcaccatcca gtaaagtctc ggtaaaacca atcagtgaag tcacaggagt
     5821 ttttaattcg tgagagacgt tgccaacgaa atccttttgt agcttttcta aacgtcgcac
     5881 tttcgttaag tcatacgcca cccctagaat ctgtccggta ccttctgaat tagtaaagta
     5941 gcgcaaactc aagtctaatg tctgccgacc ttctgtaagg gtgatctcct gatggatcag
     6001 cggatgctca ggagtcactt gatgaatcag ctgaatgagt tttggctctt gaatgacttc
     6061 tgtgtaccgc tgttcaggtt gatagcttac cacgtttaaa tgtagctgca tctttggatt
     6121 aagcagtagt aaacgagaat cagcatcatc aatcaggaat acgccaatca tcagttcgtt
     6181 cagtaacgta tataattgct cttctgtggt agtatacgcc cgatacatct tactcatttg
     6241 ttcgctcaac gcattgatcg tctgatacaa ttcttcccat tgatcgggtg tttgcatgat
     6301 tacttccgcc tgattaggat tttgcaccat tttttttagt acgggcagca cggttttcaa
     6361 tggctggttt ttttgataga tcagataata gatcattcct gcaagaacaa ggaagaaaga
     6421 cagaaagaag aaaaagaccc aacggcgaaa actctcagtt ctcggtaaaa aaccgcttgt
     6481 cggttctgcg atacgtaaaa tggcttctaa ctggccactt tttttgactg gtaatgcgac
     6541 atataaaaga tccccattca aagtagtact tttgcgcaaa gcgctaccta ggttcccacc
     6601 attcaatacg gctttgattt cgggacggga gtttcgctgt tcattcaatg tttcattgtt
     6661 tgtgtcaaat aagatctttc cagtagcatc cattaaagta atccgttcgt tcgactgatg
     6721 gacgaattct tccaaagcag ttttgttttg cgctgcttgg aggttttcga catctaattg
     6781 ccggatcagc agttgtgctt tttttgtcag gtagctttct tgctgttcca cgatctgctg
     6841 ttgaaaataa tgggaaatca attgccagcc accaaaaaac aaactaacta aaagaataag
     6901 aaagaagaga cgttcataaa tttttttcca tttcatcgtt tgggttcctg aaacttatag
     6961 ccaaatcctc taatagtcac caagtacttt gggtgttttg gatctcgctc gattttttct
     7021 cgcaaatgac taacgtgtac atctacgatt cggctttgtc ctgcgaagtc aaaattccaa
     7081 atgcggtcta gcaatgtgtc tcggtcgatc acacggtctt ttcgtttcat gaaataaaca
     7141 agtaattcaa attctttcgg tgttagttca atcagatggt cgtctacggt cacttgataa
     7201 ttggtcaaat cagcagtgat ttgtccaatc gatagatatt caggctcagc ttcatctttt
     7261 gattgcttac gaggttcaat tcgtctgaat attgctttca tacgggctaa tacttcgcga
     7321 ggactaaatg gtttggtcaa atagtcgtca gcacctattt ctaggccaat gatccgatcc
     7381 acttggtcat ctttagccgt cagcatcaaa atcggtgttt catttttttc ttgacgcagc
     7441 cgctgagtga tctccatgcc atccatcgtt ggaagcatca catctaaaat gatgaaatca
     7501 aatgattgtt ctaatgctaa ttctaatcct tcgcctccat ctgtggcact ggttaccttg
     7561 tagccttctt tttccaaatt gaacgtcaag agcgttacaa tagaaggttc atcatcaaca
     7621 actagtattt ttttcattca aatctccttt aaataggttt cattctgttt atattttagc
     7681 atagaatcag tacaaagggc tattttacaa aagaaataaa tggtataata ggaaggcact
     7741 ttgctgaata gaaaggaaga gcagtcaatg attggaatca gtgcatgttt aggcggtctg
     7801 gcctgtcgct atgatggaca gaaaaaagaa gtaccagaat tgatggaact agttgaaact
     7861 ggagaagctg tcatggtctg tccagaagtg atcggcggat taccaattcc tagagatccc
     7921 gctgaaatca ttggtggaaa tggattcgat gtgtggaaag atcaagcaaa agtgtatgga
     7981 cgacaagcgg cgaagatgta acggaagcgt acaaaaatgg cgcgatcaaa gcctatcaaa
     8041 aattgcagga aaaacacatt gatctagtca tcatgaagga aaaaagccct tcatgcggaa
     8101 cccattcgat ttatgacggg agtttttccg gaataaaaaa aaatggtgcc ggagtggcta
     8161 ctgcttattt tattcagcaa aaaatgactg tgctctctga tgaagaatgg ctgaaaacta
     8221 gaggtgagca gaatggaaat cgaaaagacc aatcgaatga acgcgctctt tgaattttat
     8281 tcgaccttat tgacagaaaa acaaatgaac tacatggaat tatattatgc agatgatttt
     8341 tcattaggtg agatcgcgga agaatacgaa gtaagccgac aagcagtata tgacaatatc
     8401 aagcggacaa gcaagatctt ggaggattat gaaaaaaaac ttcatctttt ttctaattat
     8461 attgttcgag aacaggtatt ggaaaatatg actgcatata ttacagataa gtacccggaa
     8521 gataaaaaac tacttgaata tgtacagcaa attcaagcaa tcgaagaata aataaaagga
     8581 atgaagaaaa tatggcattt gaaagcttaa ctgaacgtct ccagcaggcg atgggaaaaa
     8641 taagaaaaaa aggaaaagta tcagaagctg acgtaaaaga aatgatgcgg gaaatccgcc
     8701 ttgccttact agaagccgat gttaacttgc aagtagtcaa agattttact aagcgcgtac
     8761 gcgaacgtgc ggtaggggca gaagtgctgg aaagtttatc acctgcacaa caaatcgtaa
     8821 aaatcgttga tgaagaattg acgatcacac ttggttctga aacagcagag ttaaataaat
     8881 caccaaaaat accaactgtt atcatgatgg ctggtcttca aggggcaggt aaaacgacct
     8941 ttactggtaa attagccaat tatttaaaga aaaatgaaaa tgctcgtccg ctcctaatcg
     9001 caggggacgt atatcgacca gctgcgatcg accaattgaa agtattaggt caacagctag
     9061 acgttcctgt atttgatatg ggaactgaag tcagcccggt agagatcgtc cgtcaaggga
     9121 tggagttagc aaaagaaaag aaaaacgact atgtattgat cgatacggca ggacgtctgc
     9181 atatcgatga aacattgatg gatgagttga aacaaatcaa agaattgacg caaccaaatg
     9241 agattttgct tgttgtcgat gccatgactg gtcaagatac cgtcaacgta gctgatagct
     9301 tcaaccagca attaggtatt acaggggtcg tcatcactaa acttgatggg gatactcgag
     9361 gcggggcagc actatcgatc cgctcagtga caggcgcacc aatcaaattc atcggttctg
     9421 gtgaaaaatt gactgactta gaagtattcc acccagatcg tatggctagc cgtatccttg
     9481 gtatggggga tatgctgaca ttgattgaaa aagcgcagca agactatgac gagaaaaaag
     9541 cggaagaact tgcacagaaa atgcgggaaa attcattcga tttcaatgac tttattgaac
     9601 agcttgatca agtgatgggt atgggcccac tggaagatct aatcaaaatg atcccaggaa
     9661 tgaatcaagt ccctggaatc gaaaacgtca aggtagatcc aaaagatgtt gaacgcaaaa
     9721 aagcgatggt ttattctatg acgccagcag aaagagcaaa tcctgatctg ttgaacccaa
     9781 gccgtcgtcg ccgaattgct gccggttctg gaaacagtgt tgttgaagtg aatcgaatga
     9841 tcaaacaatt caaggaatca agaaaaatga tgcagcaaat gtccaaaggg gatatgaaca
     9901 tcccaggtat ggaccaaatg tttggttcag gcgtcaaagg aaaactaggc aaaatggcga
     9961 tgaatcgaat gatcaagaaa aataagaaga aaaagaaaaa acggaaataa gatgaaaaaa
    10021 acagcttcgg tacagactga aaatgtctac tgccggagct tttctatcag caatttttat
    10081 tctttactaa tacaattact ctaaacgaag aggtggcaca gatgagatgt ccgtggagtg
    10141 aacaaacaga aagtatgcgg caatatcatg atactgtctg gggtgttcct gaatatgatg
    10201 accaaaagct gttccgaaaa ttgatgcttg atattaatca agccggattg agctggcaga
    10261 cgattttaaa taaaagtgaa gcattcgatg aagcatatga tcgattcgat attaaaaaag
    10321 tcgcaaatta tggagaaaca aaaatcagtg aactaatgga aaacaaagga attattcgta
    10381 accgaagaaa aatcgaagca gccgtccaaa acgccaaagc agtcttgaaa attcaagaag
    10441 aaatcggcag tttttcagag tatctttggt cgttttctaa tggaaaaatc gttgattctt
    10501 cttatcattc acaagaagaa gtcccaacaa caagtcctct ttcagatgaa ttagcaaaag
    10561 atctaaagaa aagaggattt aaatttatcg gaagcacaac aatctatgct tttttagaag
    10621 ctgtcgggat catcaatgat caccttgaca gttgtttccg caaagaagag gtcgtacgta
    10681 tcggcagaaa gggcgaataa agcatgcgaa aaatcatatt ttatggtgct ataagtttag
    10741 atggctattt ggcaacgaaa acggatgatc ttcaatggct ttttgacact ccaacaggta
    10801 agcaaaccac ttatgaagct ttttatgaaa caatcgatac gaccatcatg ggcagaaaaa
    10861 cttatcagga agcaaaaaaa tatttggaga ccgaagcaat ttatccagag aaaaagaatt
    10921 tcgttttttc cacccacgca caattacaat tgccagatgc tgaggtcgta aacgaagatc
    10981 ctgttgcttt tctaaaaaat ctacaaatga cagaaggaaa agatatctgg gttgtgggtg
    11041 gcggtcgatt gatcaaaccg ctattggaac atcaaatgat tgatgaatgg tatatccaga
    11101 ttacccctgt attattaggg gacgggattc ctttattcca aaaaggaaca tatgaagcgc
    11161 gttttgaaat gctagacacg acacgattcg gtgaatttat cgaattgcat tatgtacgaa
    11221 agtagaagta aataaaataa aaaaggcaac tatatgcaga aatgtcctgt acatagttgc
    11281 cttttttatt accgttatgc tttttactct gttaatttgt tagaaaaatc tagatacgca
    11341 tctaaaatcg tttggaagaa acttaatgtt ccttcaacga tattaccatt ttcatcaatt
    11401 agattcgcaa cgtttccgat atatgcttcc ggttgctgca aggttggcac attcaaaaag
    11461 acaagtgatt gtcgtagatg gtggtttgcg ccaaagccgc cgatcccacc tggtgatgca
    11521 gtaacgacta aacctggttt atgatcccaa acgctgtgtc cataaggtct tgagcctaca
    11581 tctaaagcat ttttcaatac tgctggcaca gaacggttgt attcaggagt aacgaaaacg
    11641 acaccgtcta gtcccctcac ttcctcacga aaacgagtcc attcagcagg agcctgttct
    11701 ggagtttcga gatcctcatt gtaaaatggc agatcatcga tttttacaaa tacactttcg
    11761 tacccttcag gaagcaattt cgcaaaagct tctgctactt ttttgttgta agaatctttt
    11821 cttaaactac caataaaaaa tccaattttt tttgtcatac gatttttcct ccttcaaact
    11881 atctataaca atcttacaaa aaataagtaa ctggagcaaa taaaaacact tactgacaaa
    11941 agctacatag aagatagatt acttattttt aacaaaaaag aagtctaaaa tcttctattt
    12001 cctaaaaaaa atcgaattta atcaagctgt aaagaaaaaa agctttacag ggtaaaaaaa
    12061 aactgttaca ctacatcttg tgaataaaac aatggaggtg gaaataaata atggcagtta
    12121 aaatccgttt aaaacgtatg ggttctaaaa agagtccgtt ttaccgtatc gtcgtagctg
    12181 attcacgttc tcctcgtgat ggacgtttca tcgaaactgt aggtacttac aatcctttga
    12241 aagaccctgc agaagtagtt ttaaaagaag acttagttct tgactggtta tcaaaaggtg
    12301 cacaaccttc tgacactgta cgtaacatcc tttcaaaaga aggcgttatg caaaaacacc
    12361 acgaagctaa attctcaaag aaataaggtg accggatatg aaagatttaa gcgacttagt
    12421 cttaacaatc gttcgtccgc tagtcactta tcctgatcaa gtcaagttag acgtcgtaga
    12481 gtcgaaagac ttttacgagt acaatctaac agtggctcct gaagatattg gccgtatcat
    12541 tggaaaacaa gggcgtgttg ctaaagcaat ccgcacaatc gtttacggtg ttcggatcaa
    12601 tgcaccgaaa aaagtgcgtt tgaatatcat cgatgataag gaaaagtaaa taaacgtgct
    12661 gtactcgaat tttcgagtgc agcttttttg tttttttatt aattgaagaa atgattattt
    12721 ggcaaaacaa gcaagaaagc gtatccttat aggaggaggg agtgaacagc caatgagaaa
    12781 gaaaatgtta tttattccat ttgctctatt gttaagcgct tgtagttcgg ttactcaaga
    12841 atcagacaat acacatctat caagcagtat atctgaaact gttaccagtc cagaaaaaag
    12901 tagtaccaaa acggctacca ccactgaaca aacaatggct acctcaaata atgagaaaaa
    12961 gactgcttta gaccagttga aagaacaaca gccaaatgtt cccatgcctc tagatgtacc
    13021 agtctcttca ggctatctca atatcgcagc gacacataca aagcaaggtt attctatttt
    13081 atattacaga acagatcgtc ccctcgggtt gaatgctgac gaattgaatc aagaaacgcc
    13141 tattgcaacc tatctatatc aatatgggtt tgcttctagt caagaaacaa tccaagtttt
    13201 gcagcccttt gagatcgaca caaatggtca gcaagtggac ttaggttctc gaatcacagg
    13261 gtatcagcaa ggtgcagcag gttcaagttt tcttgaatgg caagaaggaa actggcgtat
    13321 tcgaatccgt gggaataata tagaaggcca agatccctta ctattagcta aagaaatcgt
    13381 agcttatttg gaagaaaaca gtctaccagc acctgaacaa tttggtaaaa ttactgttga
    13441 tatgggtgat acgacgaatc gagccgtaga agtaagctgg caagaaccga aaaatgccta
    13501 tacgatcact catcaagatc ctatgtctgc gttgaagatg gcagtttcta tgaagaggtt
    13561 gtgaaatcag cgcgctgatc tgagcccatc atttaactcc aagtcacagg aagtaatcaa
    13621 aaatagcacg ccgcattttt gcataatttt ggcttaatac cttaaaagaa aactagaatt
    13681 gcctcttcac acatgctaaa ataaaacaga caaaaaagaa atggggatat aagttgactg
    13741 aatacttgaa tgtaggaaaa atcgtaaaca cacaaggtat caaaggcgaa gtccgtgtta
    13801 tctcaacaac ggatttccca gaagaacgtt acaaaaaagg aacggtgtta acactattcc
    13861 aagacggaaa agcacctgtg gaattaacag tcaaaagtca tcgcaaacat aaaaattttg
    13921 acttattgag ttttgaagga catccttcta tcaatgatgt ggaaaaatat cgggatggca
    13981 tattaaaagt gtcaaaagac aactctgtag atctagctga aaatgaattc tattaccatg
    14041 agatcatcgg tctgcatgta ttagaagatg gaactgagtt aggtaaagta aaagaaatct
    14101 tgtcaccagg tgccaatgat gtttgggtcg ttcaacgtcc gaaaaaagct gatatattgc
    14161 ttccatatat cgcttctgtc gtcaaagaag tcgatttaga agctggagtg gtccgtgtag
    14221 aaattccaga aggactgatt gacgatgaag attgatgtat tgactttatt tccaagaatg
    14281 tttgaaggtc ctatggggga atccatcatc ggtaaggctg tagataaagg attattagat
    14341 atcaatatct ctaacttccg cgattattca gataacaaac atcagacagt agatgattat
    14401 ccatacggcg gtggagcagg tatgctgctc aaagtccagc ccatctatga taacatccaa
    14461 gccattgaaa aagctgcacc ggatgtcaaa aaaagagtaa ttcttcttga cccagctggt
    14521 aaacgattcg atcagaaaat ggcagaagaa ttttcacaag aagaacactt agtattcatt
    14581 tgtggtcatt atgagggata tgatgaacgt atccgcacat tagtgacaga tgaagtttcc
    14641 ttaggagatt atgtccttac tgggggagaa ttaggtgcga tggtcatgat cgatgcaaca
    14701 gttcggcttt tgccagatgt gttagggaat cagacttcag ctcaaacgga ttcttattca
    14761 accggtttat tggaacatcc ccaatatact cgcccggcag aatataaagg gatgaaagta
    14821 ccagaagtat tgacaaatgg aaatcataaa ttgattgaag aatggcaatt aaaagaatca
    14881 ctaagaagga cctatcaacg tcggcctgat cttttggaaa cacttgaatg gacacctcaa
    14941 atgacgaaat ttttagaaga aatcaagaaa gaagaacaag aaaaaacagc agatgaagcc
    15001 aagtgacttt ttctaaaata ttctttacag taggttgata atatgttagt attttatggt
    15061 gagtgcaaaa gcacttaact attacgatat tccgctatga gaaaagctca taagaatatt
    15121 tggaataagg agaagaaaac catgaatcca ttaatcgaag aattaacaaa agaacaatta
    15181 cgttctgaca tcccagcgtt ccgccctggt gacactgtgc gtgttcacgc aaaagttgtt
    15241 gaaggtactc gtgaacgtat ccagttattt gaaggtgttg ttatcaaacg ccgcggtgct
    15301 ggaatcagcg aaacttatac agtacgtaaa gtttctaacg gagtgggcgt tgaacgtaca
    15361 ttcccattgc atacaccacg tgttgcaaaa atcgaagtag ttcgctacgg taaagtacgt
    15421 cgtgcaaaat tgtactacct acgtgcatta cacggaaaag ctgctcgtat caaagaaatc
    15481 cgtcgttaat cattgttatc agactgagaa agaacccttg gtattcaagg gttctttttt
    15541 cttagcatgt aatttgaaca ccctgatcca gtttttttct ttaattattg gtaggggaga
    15601 ataatggatt agaataaatc tacctataag tagtagtaaa aaaaagagca ctatgataat
    15661 atctttctta agagtaaccg ctttaataaa aaatccagaa tattctaaca taaatggagt
    15721 attcttagaa tcaaaaggag aaagaagatg gtttatactt atacggagca agaaaaaatg
    15781 aaagtttgag acacattcat gaatgatgga aaagtaaaac aagtaccaag ttcaacaaaa
    15841 aagaaaaaca tcctattgaa agaagtcttg aaacgctttg accatggagt gacttataca
    15901 gaaacagagg ttaattcgat actgctgaac gtattttcta gtggcgatta tgtcgaacaa
    15961 agacgttatc taatcacatt tggctttttc aaaagaagtt cagacggtcg ggcatatcag
    16021 atgatgggaa ttgaaaatta gaagttttaa tttatactca ttgaaaaaag ttcaagtatg
    16081 cgatattggt tctacaccgc atacttgaac tttttttgtc atctgtatct ataatacaaa
    16141 gccaagaacg ttattcaaaa tatggatagc tatgataaaa gctaatgagc gattcgcagt
    16201 taaataagca atcgtcagta aaatcgttcc aggagcgtac atgaaaaaat caattggatg
    16261 cgttacatga ataaagataa ttctctttta tttgtacgaa taaataccaa aacgtacctc
    16321 ctaaaattag attcaaagaa gatagcaaag aggaaaaaga tagttctgca gcagctatag
    16381 cggcatgtgg attgctagaa ctttccaaac aactgcctgt ttcagatcct cgtcatttcg
    16441 attacgaaga gatagcaatc aaaatcttgg aagaattaca gaaaaactat acaacgaaac
    16501 gagttaacgg atcaaacggt ctgcttctcc atgccgttta tgataaaaac agcttaaaag
    16561 gtgtagatga atgtgtgatc tggggcgatt acttttatgt agaaggaatc actcgtctag
    16621 ctaaaacatg gtactgttac tggtgatgta taagagaaga ggaggattca tataatgaag
    16681 cgatggaaaa aaatgatgat tggatcaata gttttaggaa tgtcactcgt atttggtgct
    16741 tgtggtaatc aagaagacag tagtgaagaa tcagcaaatg aaattaccgt ttcgacatgg
    16801 aattatgaaa caacacctga attcaaagcg ctctttgaag cattcgaaaa gaaaacggga
    16861 atcaaagtga aagcagtaga tattgcttca gatgattatg atacgaaact caccacgatg
    16921 ctttcttctg gagacacgac agatgtattg acgatgaaaa atcttttgtc gtattcaaat
    16981 tatgctttac gagatcagtt agtcgatcaa acagaacgaa ttagagaatt agacactgat
    17041 gctgctgaag aaacatatga aatgtatgat atcgatggaa aaacatatgc attgccatat
    17101 cgaacggact tttgggtact atattacaat aagaaaatgt ttgatgatgc aggaatcgaa
    17161 tatccaaaaa atctaacttg ggacgaatat gaagatttag caaaaaaact tagtaaaaat
    17221 gacggacaag tttacggagc atatcaacat atctggcgtt cgacaatcca agctattgca
    17281 gctgctcaaa acgaggcgaa tcttgttgaa ccagattatc aatatatgac tgattattat
    17341 gatcgagcat tgaggatgca aaaagaaggc gcgcagatgg attttggcac ggctaaatca
    17401 acgaaagtaa cctatcagtc tcaatttgaa gaacaaaaag cagcaatgat gtacatggga
    17461 acttggtata tggctggcat actcgcaaac aaagaagcaa gtaagacaga agtagaatgg
    17521 ggaattacag ctattcctca gaagaaaaaa ggagaatcgg tcacgacgtt tggctcacca
    17581 acagcatttg ctgtcaataa aaactcaaag aaacaaaaag cggcgcaaga atttattgaa
    17641 tttgcagcca gtgaagaagg agcaaaagta ttagcaggag taggagtagt tccttcatat
    17701 cgtacggatg agattgatca gctttatttt aatctcgctg gaatgccaac ggatgaaatt
    17761 tctaaaaaag ctttttctcc tgatgaaatc aaacttgaat ttccgattga tacgtatggg
    17821 cctgcaatcg ataagatttt acaagaagaa tatgacttag ttttggttgg agatgaaacg
    17881 ccggaaaaag gaacggtaaa tatggagaaa cgtgtagctg cggaaaaaga ataatcatga
    17941 aaggagagaa gccaagagat aaaacactct tggtttcgtc atcgaaatgg agaatagtat
    18001 aaataagaaa gctacaaatc atttgcgtag aaaacgaacg tggatcgctt attcgtttat
    18061 cgccccgaat ttcattggtt ttttcgtttt tacattaata ccaatcctgt tttcgcttgt
    18121 actagcattt atgaaatggg attctttttc aacgccagaa tttgctggac tagataactt
    18181 tcgtaaaatg gccaacgatg agacattttg gatttctttg aaaaatactt ttttatatac
    18241 cgctgctgta gtgcctggca cacttgtttg ttcgttaggg ctagctttac tactaaatca
    18301 gaaaattaga gggatgaagc tttttcgtac gatatttttc tttccgtatg ttacttcctt
    18361 agtagcaatt gctgttgttt ggaatatgtt gtttcatcca acagtgggac ctattaatat
    18421 ctttttaaga cgatttattg aacatcctcc aggttggact tcaagttcaa attgggcgct
    18481 ttgggcaatt gtaattgtca gtatttggcg agggatgggt tattacatga ttctatacct
    18541 tgcaggacta caaagtatcc aaaaagaact atatgaagcg tcttcgctag atggagcaaa
    18601 ccgttggaaa caatttttga atgtgacatt accttcgttg agaccaacaa ccttctttgt
    18661 aacgatcatg cttgtcatca attgtttcaa ggtgtttgac cttgtgcaag tgatgacgga
    18721 tggcggccct ggtcgagcga caaatgtgct ggtttaccaa atctacaatg aagcattcaa
    18781 aaaatttgat tttggttatg cttcagctat ttcacttgtt ttgttcgtaa ttgttttggg
    18841 cgttacggtt gttcaatttt cttggaataa gcgtcgtact taggaggtgt gatatggaag
    18901 agagtgttcg aaatgaaaga aaaaaagcaa aaattcgttc aaaaaacatg ccctttattc
    18961 aatggttggg tatgattctg ctgattgtat tagctttatt gacgatcatt ccttttttat
    19021 ggatggtttc tgcttcattc aaagcaaata atgaagtgtt aacgattccg attcaatgga
    19081 tccctaaaac ttggcattta gagaattatc tggttatttg gtctcgtatt cctttagtga
    19141 cattttttaa gaatacagct tttttaagcg ttgtgatcac gttgattcag ttgtttactt
    19201 ctagttttgc tgtttacggg ttttctgaac taaattttaa agggcgcgat attttatttt
    19261 tagcatatat cggcacgatt gctgtccctt ggcagtctta tatgatcccg cagttcatta
    19321 tgatgagaaa agtgggttta acagatacgt tgtggtcgtt ggtgctatta caagcgttca
    19381 atgcttttgg tgtgttcttg ttgaagcaat attacagtag tatcccagat tctttatgtg
    19441 agagtgcgcg gatcgatggc ttatcagagt gggaaatcta tcgcaagatc attttacctc
    19501 ttacaaaacc ggcgattgcc agtttgacga tcatcacatt cgttaataca tggaacgatt
    19561 atatggggcc attcatttat ttgtcttcta cggaaaataa aacaatccag ttagggttga
    19621 aaatgtttat tgggctattt gatgcagagt acgcattaat catggctgcc tcagttgttt
    19681 ctgttcttcc tgttgctttt atatttttag cgatgcaaaa atattttgta gaagggatcg
    19741 cttcatcagg aatgaaggaa taggaggtga ttatgaaaga gcagcgtttt gacaaaaatg
    19801 tttatatgga attcttttat tggttgtatc aatcattggc aagtagcctt tgtttttggt
    19861 gtgtcaatat cttgtatata gcagctgcgt tccttttgtc gatagatgga aggaatgtct
    19921 tttcctttat tttttcttta ctttttattg gtccaggttg catcgtgatg ataggtatga
    19981 cagaagaatt agcaaaagaa aaaagttttt caccagtacg tttgttcata aagacgtttc
    20041 gccaattttg gctaaaggga tttttttatt ggctatttgc ttggatagtt agtgtgataa
    20101 tgatttttga ttgtttcttt tttatacgtt tttcttatgg aaaatggttg attccgttgt
    20161 ttgttttact tgcttgtttt acttgcttgt ttatcagttt cctttagcat caactgctgg
    20221 tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat agcgttctac
    20281 tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac aagtttgttt
    20341 ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat cgtatttggt
    20401 ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac tttataaatt
    20461 gaaactttca attaagaatg acagtttttt atgtaaaaac tgtcattctt tttcattttt
    20521 tgaaacatat ggctaaacaa atgaaataaa acatgctata cttttgaatg aaacaggttt
    20581 agaaactgta tcacttattt gtgattattt ctaactaata attaaaaata aagcataaaa
    20641 aggacgatgt tcaatggctg aaaaaatgaa acaaggttcg aaatctgtag tagaaagttt
    20701 gattaatcat catgttgatt atgtattcgg tataccaggt gcaaaaatcg atggtgtatt
    20761 taatgaatta gaggatcaag gtcctgaatt aatcgtgact cgtcacgaac aaaatgctgc
    20821 atttatggca caagcaatcg gacgtattac aggagagcca ggagtagtta tcgcaacaag
    20881 tggtcctggt gctagtaact tagctacagg tttggtaaca gcgacagcag aaggtgaccc
    20941 agttttagca attgccggac aagtaaaacg aagcgatcta ttgaagttga cccatcaaag
    21001 catggataat gcagcactgt tccagccaat cacaaaatac agtgcagaaa tccaagatcc
    21061 agaaacaatt tcagaagtga ttgccaatgc ttatcgtatg gctaagagtt caaaaaaagg
    21121 cgcgagcttt atcagtatcc cgcaagatgt agtggatgca cctgtccaag gtaatgtcat
    21181 caagccattg agcgatccta aattaggttc tgcttctgca gatgatatcc gttacctagc
    21241 tgaacgcatt agagaagcaa aactaccggt actattagta ggtatgcgag gatcaagtga
    21301 aaaagaaacg ttagccatca ggcaattagt tgaaaagaca gcattgcctg ttgtagagac
    21361 attccaagca gctggagtga tctcacgtga attagaagcg catttctttg gtcgtgtggg
    21421 tttatttaga aaccaaccag gagatatgct tttgaaacga agtgatctag ttattgcaat
    21481 tggctatgat ccaatcgaat atgaagcaag aaactggaat gcggaaaaag atgcgcggat
    21541 cattgtgatc gatgaagcgc cagctgaaat cgatcctttt atgcagcctg aaagagaatt
    21601 gatcggtgat atctcagcca ctcttgattt attgacaggt tcattagagc ctcaacaagt
    21661 gtcagaagat gcaaaagaat atttagcatc tcttcaagca aaattaacgg agcgggacat
    21721 tgttcaatca aaaggagaag caggtatctt gcatccttta gaagttatta acacgcttca
    21781 gtcaaaagta acagatgata tgactgttac cgtagatgta ggtagtcatt atatttggat
    21841 ggcacgccac tttagaagtt atgaacctcg tcatttgtta ttcagtaatg gtatgcaaac
    21901 gcttggtgtt gcattgccat gggcgatttc tgctgcattg gtgcgtccaa atacacagat
    21961 cgtatcagtt tccggcgatg ggggattttt attctctgcc caggatttag aaacggcggt
    22021 acgtaaaaaa ttgaatatcg ttcatttgat ttggaatgat ggacactaca atatggtaga
    22081 gttccaagaa aaaatgaaat atcagcgggc gtcaggtgta gactttggtc cagttgattt
    22141 tgtgaaatat gcagaagctt ttggcgctaa aggaatccga gctacaagtg tagaggaatt
    22201 agaaaaagct ttagaagaag gatttgcgac agaaggaccc gtaattattg atattccgat
    22261 tgattaccgt gataatgaga aattgggaga aacaatctta ccagatcaat tctattaagg
    22321 aagtgtcgac atgactgaaa aaatcttata ccagcacggg acattaggag ctttgatggc
    22381 cggcttgatg gatggaacag aaacgattgc tcatatatta gaaaaaggaa ctctgggatt
    22441 gggaacattg catgggcttg atggtgaagt catcttttta gatggcgtag cttatcaagg
    22501 aagatcagat ggctcagttg cccaattaga tggaagtgaa cttaccccct atgcagcaat
    22561 tacagatttt acgccagata ctagtttttc tgtctcaaaa actgcagatg gagaacaatt
    22621 gaaaaaagac atattagtaa gagaagccgg ggaaaaccta tttttggcag tgaagataac
    22681 tggattattc aaaaatatgc acatccgtat catgccgaag caagaaaaac cttacagaag
    22741 actagcaaaa atttcagagt ctcaaccaga attccaacaa agcaatgtcc aaggaacatt
    22801 agtcgggttc tttacgcctg aattattcca aggagttgct gcagcgggat ttcacctgca
    22861 ttttatcgat gatacacata catttggcgg acatgtaatg gattttgaag tggctgaagg
    22921 aaaagttgag attagccgca tctcgtccct tgtacagcat tttccagttg atgatccgac
    22981 ttttgttcac gaaacgattg attatgctga tttagcagca gaaatccaac aagcagaata
    23041 gaaaaagaca gcgagatgcg ttcaaggtga ttaacctgac gtatctcgtt tttttgagga
    23101 gaaaacctag cgtttacaaa aaaactgagc tataatcttc tccatagatc aaaaaggagc
    23161 ggtttttatc atgtggacag aaaaacagaa aaaagatgca tacgaaattt tattattaca
    23221 gcaacaagga ttattagaag cagaagataa ctggttagca aatttagcaa attcatctgc
    23281 attgttgaat gagactttgc ctgagactgt ctttgcagga tattatttat tcgatggtaa
    23341 tgaattgatt ttaggaccgt tccaagggcg agtttcttgc acacgtatca agatgggaaa
    23401 aggagtttgt ggagaatcag ctgaaaaaca agaaacattg atcgttgatg atgtcaaaac
    23461 ccatgcaaat tacatttcct gcgattcagc cgcacaatca gaaatcgtag tgccaatggt
    23521 aaaagaaggt aatttaatcg gtgttttaga tatcgattgc ggagtaacga aagggtatga
    23581 tgaaatcgat caagcatttc tagaaaaata tgtagatctt ttattagcaa attttaatat
    23641 aaatgctttt tcatttatta ataactaaaa tcgtctattg aaacaaaaaa gaagagaaat
    23701 caagaataaa aagagccgga aagacagtgg gcatttctgt ttttcggttt ttttattttt
    23761 ttataaaatc acaagtgtta ttgattttca taatcatatt ttaatgttat tatcatttta
    23821 aataatgaaa aaacattaag gatggatgaa atatgaataa cgaaactatc attttaggaa
    23881 aaaaatatat ttgccaacct attggcttga aacaaaaagt gattggagaa gtaatcagta
    23941 aattagaaaa ttgtgttgtg atctgcgtag acgaatatca tgacgtcgat cgcaatgaaa
    24001 tattagaaaa atgcggaaaa gtagtggcaa aatatactca cgtttatgag ttggaaacaa
    24061 cagaatatct atataactat agcaacaaat atgaacatac tttagtttca taaagattta
    24121 aataaagtgc cttcaaaagc gagaagacca agcttttgaa ggcactttat ttagttggca
    24181 gtgattgttc atgatttttg atttattcaa aaggttcgcc tagagaatct gtctctgtaa
    24241 cgaggcctgg tggagaaact cgataaaaac ctatactgcc agaactgtcc tattttcgga
    24301 tagacaaact agtagtttta aaaagatcat ccgatccaat catttcaaaa aatgcaaaac
    24361 tgatatcagg atcatttagc tcaggcttgt tatcgtaaag catttgtaaa ggttgcattt
    24421 agttaggagt aaacgcgaaa ctatcatcat tatttgctga agaagatgaa gaagctaatt
    24481 cagagtttgt ttgaaataaa ggagacgtgc tgacagtttc tttaccctgt tttttgcaga
    24541 ggtagaaact tttatatcgg aagtttctac cggagaattt ttctcatttg tagaaattgt
    24601 tgaatcgata ctattcgaaa tttgcgtatc tgaaggtatg ttctttgatg cagaagtccc
    24661 acaagcagta agtaacaata aatttgataa actgataaac agaattcttt tcattatgta
    24721 cacactcctt atagtatcgt ttagcataca cctatgctca gtattaggca aaatcaatgc
    24781 aaaactatca agtcttttat agtatctatt agtcttagta atacatatat ggagagggtg
    24841 atatcccagt tcaaaccaga tacattggtt accatctgta ttaacgatta tgcctctaaa
    24901 cgcttttttt atgaaaaaat ttataagtga aaacgtaggt atgatattat ctagaggtaa
    24961 tttttttggg tatttaaata gttgctagga ggatagcttt tggattttta cagtaatttt
    25021 atcttaataa tagcaatatt attacttcta aatatttggt tttttgataa gagtagaaat
    25081 gcagggatag gttttagaac caaacgaagt acgtcttctg aaaaaaagtg ggtatattca
    25141 cagactattt tttacggagg ggttatttca atcagtttac tttcttcaac actttattct
    25201 tttaatgtta tagacgtttc catgtcaaat tttatatcta ttattggaat ccttatttct
    25261 gcaattatta cacaactact tcttgtgttt gaagagaagt caaaaaataa ttaaagcaat
    25321 tatgcctttt agtacaggaa ttattacttc ttacaaatgt atagcgaatg tgaagcctgc
    25381 tgttttaatt gttctagaaa aacttttgag tgaacaatta ttttatgtta ggatgaatta
    25441 atttctctag agtttata
//
LOCUS       DAZKCW010000038        25329 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000038 DAZKCW010000000
VERSION     DAZKCW010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.038"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            12..84
                     /locus_tag="ACG84Z_001783"
     tRNA            12..84
                     /locus_tag="ACG84Z_001783"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="ACG84Z_001784"
     tRNA            88..160
                     /locus_tag="ACG84Z_001784"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="ACG84Z_001785"
     tRNA            168..249
                     /locus_tag="ACG84Z_001785"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="ACG84Z_001786"
     tRNA            267..339
                     /locus_tag="ACG84Z_001786"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="ACG84Z_001787"
     tRNA            351..422
                     /locus_tag="ACG84Z_001787"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="ACG84Z_001788"
     tRNA            439..524
                     /locus_tag="ACG84Z_001788"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="ACG84Z_001789"
     tRNA            535..608
                     /locus_tag="ACG84Z_001789"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="ACG84Z_001790"
     tRNA            618..691
                     /locus_tag="ACG84Z_001790"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="ACG84Z_001791"
     tRNA            711..783
                     /locus_tag="ACG84Z_001791"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="ACG84Z_001792"
     tRNA            811..884
                     /locus_tag="ACG84Z_001792"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="ACG84Z_001793"
     tRNA            898..971
                     /locus_tag="ACG84Z_001793"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="ACG84Z_001794"
     tRNA            995..1084
                     /locus_tag="ACG84Z_001794"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="ACG84Z_001795"
     tRNA            1097..1170
                     /locus_tag="ACG84Z_001795"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="ACG84Z_001796"
     tRNA            1189..1264
                     /locus_tag="ACG84Z_001796"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="ACG84Z_001797"
     tRNA            1266..1336
                     /locus_tag="ACG84Z_001797"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="ACG84Z_001798"
     tRNA            1350..1423
                     /locus_tag="ACG84Z_001798"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="ACG84Z_001799"
     tRNA            1448..1535
                     /locus_tag="ACG84Z_001799"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="ACG84Z_001800"
     tRNA            1557..1628
                     /locus_tag="ACG84Z_001800"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="ACG84Z_001801"
     tRNA            1651..1740
                     /locus_tag="ACG84Z_001801"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="ACG84Z_001802"
     tRNA            1753..1826
                     /locus_tag="ACG84Z_001802"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="ACG84Z_001803"
     tRNA            1845..1917
                     /locus_tag="ACG84Z_001803"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="ACG84Z_001804"
     tRNA            1921..1993
                     /locus_tag="ACG84Z_001804"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="ACG84Z_001805"
     tRNA            1998..2068
                     /locus_tag="ACG84Z_001805"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="ACG84Z_001806"
     tRNA            2081..2154
                     /locus_tag="ACG84Z_001806"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="ACG84Z_001807"
     tRNA            2166..2237
                     /locus_tag="ACG84Z_001807"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /gene="metK"
                     /locus_tag="ACG84Z_001808"
     CDS             2503..3696
                     /gene="metK"
                     /locus_tag="ACG84Z_001808"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFP9162623.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="ACG84Z_001809"
     CDS             3826..5298
                     /locus_tag="ACG84Z_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFP9162624.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="ACG84Z_001810"
     CDS             5381..6169
                     /locus_tag="ACG84Z_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9162625.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="ACG84Z_001811"
     CDS             complement(6236..6904)
                     /locus_tag="ACG84Z_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFP9162626.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="ACG84Z_001812"
     CDS             7019..8731
                     /locus_tag="ACG84Z_001812"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162627.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10503
                     /locus_tag="ACG84Z_001813"
     CDS             8734..10503
                     /locus_tag="ACG84Z_001813"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162628.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(10708..11274)
                     /locus_tag="ACG84Z_001814"
     CDS             complement(10708..11274)
                     /locus_tag="ACG84Z_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9162629.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(11274..12230)
                     /locus_tag="ACG84Z_001815"
     CDS             complement(11274..12230)
                     /locus_tag="ACG84Z_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFP9162630.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(12230..12886)
                     /locus_tag="ACG84Z_001816"
     CDS             complement(12230..12886)
                     /locus_tag="ACG84Z_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFP9162631.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            13256..15274
                     /locus_tag="ACG84Z_001817"
     CDS             13256..15274
                     /locus_tag="ACG84Z_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFP9162632.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    15344..15550
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15701..18115
                     /gene="leuS"
                     /locus_tag="ACG84Z_001818"
     CDS             15701..18115
                     /gene="leuS"
                     /locus_tag="ACG84Z_001818"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFP9162633.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            18463..20016
                     /locus_tag="ACG84Z_001819"
     CDS             18463..20016
                     /locus_tag="ACG84Z_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFP9162634.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(20397..22181)
                     /locus_tag="ACG84Z_001820"
     CDS             complement(20397..22181)
                     /locus_tag="ACG84Z_001820"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162635.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(22196..23917)
                     /locus_tag="ACG84Z_001821"
     CDS             complement(22196..23917)
                     /locus_tag="ACG84Z_001821"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162636.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            24017..24778
                     /locus_tag="ACG84Z_001822"
     CDS             24017..24778
                     /locus_tag="ACG84Z_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFP9162637.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IRERKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         7839 a         4651 c         5380 g         7459 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 taaagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag
    10561 cttctcatgt ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt
    10621 gaataaagag gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac
    10681 atatcattta tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg
    10741 cggctggttc ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag
    10801 tttggaacaa aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta
    10861 gacgacaagg atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt
    10921 gcgtgtagtc tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt
    10981 gaaaatccct gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc
    11041 ttgtagaaac aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc
    11101 atcgattgct tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc
    11161 tgctagaaaa accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg
    11221 ttgcaagatt tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg
    11281 ctcacctttt tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca
    11341 tcaattgcat tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc
    11401 cacggcgcat cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg
    11461 tcgcaaatga cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag
    11521 tcccgcaaca ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata
    11581 tctgaatcta aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt
    11641 aatccgttga tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca
    11701 tctaaataag tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt
    11761 gtttgcaatc caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca
    11821 actacttcat ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt
    11881 aaattgacta cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta
    11941 aaattttgga aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg
    12001 atttctttct ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa
    12061 ccagatacac tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag
    12121 tcaaatcctc catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg
    12181 taattccaag aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct
    12241 tctttctgta agagttatct atttgttttc ttttttctct atacactgga taagtcaggc
    12301 acagccaaga aagactgagt aagtaaccgc cgatgatatc agtaggaaaa tgaacgccca
    12361 gataaatgcg gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg
    12421 tgcgtaaggt tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa
    12481 tcatactgcc tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg
    12541 ccaatgaagg acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa
    12601 ttacaataaa tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc
    12661 ataaagccgc acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa
    12721 agagttggta gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat
    12781 cgaaaccaga aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga
    12841 caagaaagaa gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt
    12901 gaagcaatga cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac
    12961 caatgtatga ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga
    13021 aagacatttt ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa
    13081 tccttttaaa caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt
    13141 acggtaaatt acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat
    13201 attaagagaa gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga
    13261 aaacattgca agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa
    13321 acgaggggca gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt
    13381 acagccggtt cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac
    13441 agcggcattt atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct
    13501 atatgcatca gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt
    13561 atctcaagca ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt
    13621 ctacatggat acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg
    13681 acaatatcct tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc
    13741 atttggcaac ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga
    13801 tgcgacagct tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa
    13861 taatatcatc gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg
    13921 cggtggagcg actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag
    13981 caattctggt aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg
    14041 tgattctgtt tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg
    14101 gaacaacatc caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca
    14161 ggaaaatggc tcttcgacga ataattccgg taacaatacc aattcttcag gaaatgctgg
    14221 tacatcaaac ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt
    14281 ttggaagatc tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat
    14341 caagaacaat ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa
    14401 tgctggagca aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc
    14461 aagttcttct aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg
    14521 gagcgtctca aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca
    14581 aaataacttt atctacccag gacaacaact gactgtttca aacagtggat caacaaacag
    14641 cacgtcaggt aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg
    14701 cagcagttcg tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc
    14761 aaataaaaac ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt
    14821 catttatcca ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg
    14881 ttcaactact tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc
    14941 atccactggt aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa
    15001 caaacatcat atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat
    15061 ctatccagga cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc
    15121 agttactggt tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga
    15181 cagtcatgga attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat
    15241 ttatccaggt caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt
    15301 gaattccaca aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg
    15361 aagtagtaaa aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc
    15421 ttttgaactc gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg
    15481 gccgttacaa cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta
    15541 cgtcctataa aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag
    15601 aaaacaaagc aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat
    15661 aatagaaaca agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga
    15721 aattgagaaa aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga
    15781 tcctgaaaag ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct
    15841 acatgtaggg catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag
    15901 tcaaggatac aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca
    15961 atatgcgcta gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt
    16021 ccgacgccaa atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac
    16081 tgatccggag tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct
    16141 agcttatgaa gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa
    16201 tgaagaagtg atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat
    16261 gcgccaatgg atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt
    16321 agttgattgg ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg
    16381 agcaaatatt gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg
    16441 accagatact ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag
    16501 agaaattacg acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa
    16561 aaaatcagat ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc
    16621 ttatgcaatc aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt
    16681 atcttcatac ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga
    16741 attcgctcaa actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa
    16801 agctgcttac acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa
    16861 acaagaagca atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga
    16921 agtcagctat cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat
    16981 cccaatcatc cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt
    17041 acggttgcct aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa
    17101 tatcgaggag tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac
    17161 gaatacaatg ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca
    17221 taacaaaaaa gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta
    17281 cattggtgga gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt
    17341 cttatacgat atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg
    17401 aatgatctta ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc
    17461 tgatgatgtg gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg
    17521 gccattagat gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt
    17581 ggatcgtgta tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac
    17641 attgaatgat ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga
    17701 ctatgaaaat cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc
    17761 ctataaagtg gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc
    17821 gattgctcct cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc
    17881 ttacgcacca tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt
    17941 tttccaagta aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga
    18001 tgagctagaa aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac
    18061 agtcagaaaa gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc
    18121 tctttgtcaa taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca
    18181 ttctgtctca gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga
    18241 ttttcatgtt ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct
    18301 ctgtaatcat caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga
    18361 aattgagagt acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga
    18421 ttttgacgca taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt
    18481 attatcgaag tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa
    18541 agaataatgt tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct
    18601 gtatcgttcc tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa
    18661 ttaaataatt tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt
    18721 gtttttcttc tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg
    18781 cttagtcaaa gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat
    18841 ctttattttg agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag
    18901 ttattgctga gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc
    18961 ggaatgaaca cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag
    19021 tcttcgcctg gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc
    19081 attcttttag ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat
    19141 ataaatgctg cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca
    19201 aatgaagggt tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat
    19261 gatctcaaac ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat
    19321 tgggtatttg tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg
    19381 gggctgattc ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca
    19441 tggtttatct attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa
    19501 acatggcaaa cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta
    19561 ttttatggca acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact
    19621 ttgtacattt acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg
    19681 atcaatcagc cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca
    19741 cgtgaaagtt tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg
    19801 attccggaaa actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact
    19861 caaataagcg cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat
    19921 gcagggaaaa tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc
    19981 gttcagcaac tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg
    20041 ttcagcaccg agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt
    20101 gtaactcgtg attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc
    20161 gtattttaca agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt
    20221 aaaaagggat tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc
    20281 caaaaagtat cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa
    20341 aagctatcga tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac
    20401 gctatctgaa attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca
    20461 gaatgtgttc ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt
    20521 tcaatcgttg acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc
    20581 attgcttgct gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa
    20641 ataacgacag gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct
    20701 tgagataacg tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga
    20761 ataaagtgat cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc
    20821 attttcccgt aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa
    20881 accatcccaa aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg
    20941 aattcgatct ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt
    21001 tttcctgcac cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg
    21061 acttgattca tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt
    21121 tttcctttcg gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca
    21181 tctaatatct caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca
    21241 taagaagcgg tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag
    21301 aagccgatcg tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg
    21361 aaggcgagtt gattaatgaa acgaatggcc ggatagatag caaagttcat aaattgagca
    21421 cgtttaaaag cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct
    21481 tgctgattga atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt
    21541 aaaacaccca gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta
    21601 gttgtaacaa ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg
    21661 atataaaaca gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg
    21721 atacctgtca ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg
    21781 tcacctactt gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt
    21841 tcttttcgca ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata
    21901 aatgaagtga tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat
    21961 gcttgtttga tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag
    22021 agatcatcga tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat
    22081 aaactgcata gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa
    22141 cgtatcaaag cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata
    22201 ttccttgtga ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag
    22261 taccttgtcc aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg
    22321 tactgaggcg ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg
    22381 ctcttaatgc tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga
    22441 tctctgctgg tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat
    22501 aattagaacc gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt
    22561 cttctaattg agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc
    22621 ccatctgcaa gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac
    22681 tgatgtggga gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta
    22741 cttttcctat cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag
    22801 atccggtccc gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt
    22861 ctagaactgg atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat
    22921 ttgtctgatc aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct
    22981 ctgcttgcag tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca
    23041 ataccatagc tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag
    23101 tcacgacacc gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag
    23161 aagcataaac gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt
    23221 tcactttgat catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat
    23281 atgattgatt atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga
    23341 tggtgatccg atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca
    23401 gtcgataaac aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata
    23461 gagaataacg aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca
    23521 tttggcaaaa taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca
    23581 aaagagatcc agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga
    23641 aatatttctc ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag
    23701 aggcaactgc agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt
    23761 ttataactga ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg
    23821 gtacacctaa tgtaccggcg atttgtaaac agatcatcac aaaggtaagg agagcgagtc
    23881 ctttgttttt ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat
    23941 acttttcgat tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa
    24001 aaagaggtga gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga
    24061 tttgccaaaa tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca
    24121 agaagagaat gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt
    24181 tttttataga aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt
    24241 gacggagtta tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt
    24301 gatgaaacaa aaacaaaaag agataaggga gcgaaaaaaa cagttgaaat tgatgatcga
    24361 tacaaacgag gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga
    24421 gtttgaagat attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat
    24481 gagtatgcca gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt
    24541 acatttattt actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt
    24601 cttattgaaa tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag
    24661 aatgtatgaa aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac
    24721 ggatgaaaac aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga
    24781 aatatgtgtt taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct
    24841 ggttcgatta cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt
    24901 tttagaggaa atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg
    24961 taattgtcct cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat
    25021 ggtgaactga gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat
    25081 gagaatgata aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac
    25141 attattacaa tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt
    25201 aatcaaatag tccctactgt gactttcctc agctatcggt gatactaccg atagcatttt
    25261 tttgcttata aaataattat aagtatttag agatttttct tctaacattc ttcaaacaag
    25321 aaaaatcac
//
LOCUS       DAZKCW010000039        23671 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000039 DAZKCW010000000
VERSION     DAZKCW010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23671
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.039"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            288..695
                     /locus_tag="ACG84Z_001823"
     CDS             288..695
                     /locus_tag="ACG84Z_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162638.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            709..1110
                     /locus_tag="ACG84Z_001824"
     CDS             709..1110
                     /locus_tag="ACG84Z_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162639.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1112..1483
                     /locus_tag="ACG84Z_001825"
     CDS             1112..1483
                     /locus_tag="ACG84Z_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162640.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1519..1821)
                     /locus_tag="ACG84Z_001826"
     CDS             complement(1519..1821)
                     /locus_tag="ACG84Z_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFP9162641.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2079..2192)
                     /locus_tag="ACG84Z_001827"
                     /pseudo
     CDS             complement(2079..2192)
                     /locus_tag="ACG84Z_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(2575..3807)
                     /locus_tag="ACG84Z_001828"
                     /pseudo
     CDS             complement(2575..3807)
                     /locus_tag="ACG84Z_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
     gene            4061..4630
                     /locus_tag="ACG84Z_001829"
     CDS             4061..4630
                     /locus_tag="ACG84Z_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9162642.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4808..5248)
                     /locus_tag="ACG84Z_001830"
     CDS             complement(4808..5248)
                     /locus_tag="ACG84Z_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFP9162643.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5406..6170
                     /gene="map"
                     /locus_tag="ACG84Z_001831"
     CDS             5406..6170
                     /gene="map"
                     /locus_tag="ACG84Z_001831"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFP9162644.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6202..7125
                     /locus_tag="ACG84Z_001832"
     CDS             6202..7125
                     /locus_tag="ACG84Z_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFP9162645.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7201..8340
                     /locus_tag="ACG84Z_001833"
     CDS             7201..8340
                     /locus_tag="ACG84Z_001833"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFP9162646.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8333..9133
                     /locus_tag="ACG84Z_001834"
     CDS             8333..9133
                     /locus_tag="ACG84Z_001834"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9162647.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9133..9960
                     /locus_tag="ACG84Z_001835"
     CDS             9133..9960
                     /locus_tag="ACG84Z_001835"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9162648.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9965..10672
                     /locus_tag="ACG84Z_001836"
     CDS             9965..10672
                     /locus_tag="ACG84Z_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9162649.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            10772..11638
                     /gene="rfbA"
                     /locus_tag="ACG84Z_001837"
     CDS             10772..11638
                     /gene="rfbA"
                     /locus_tag="ACG84Z_001837"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFP9162650.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11652..12224
                     /gene="rfbC"
                     /locus_tag="ACG84Z_001838"
     CDS             11652..12224
                     /gene="rfbC"
                     /locus_tag="ACG84Z_001838"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFP9162651.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12246..13274
                     /gene="rfbB"
                     /locus_tag="ACG84Z_001839"
     CDS             12246..13274
                     /gene="rfbB"
                     /locus_tag="ACG84Z_001839"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFP9162652.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13372..14223
                     /gene="rfbD"
                     /locus_tag="ACG84Z_001840"
     CDS             13372..14223
                     /gene="rfbD"
                     /locus_tag="ACG84Z_001840"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFP9162653.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14258..16291
                     /locus_tag="ACG84Z_001841"
     CDS             14258..16291
                     /locus_tag="ACG84Z_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162654.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16335..17615
                     /locus_tag="ACG84Z_001842"
     CDS             16335..17615
                     /locus_tag="ACG84Z_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFP9162655.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17825..18631
                     /locus_tag="ACG84Z_001843"
     CDS             17825..18631
                     /locus_tag="ACG84Z_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162656.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18643..19863
                     /locus_tag="ACG84Z_001844"
     CDS             18643..19863
                     /locus_tag="ACG84Z_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162657.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19853..21439
                     /locus_tag="ACG84Z_001845"
     CDS             19853..21439
                     /locus_tag="ACG84Z_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9162658.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21478..23616
                     /locus_tag="ACG84Z_001846"
     CDS             21478..23616
                     /locus_tag="ACG84Z_001846"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9162659.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7568 a         3938 c         4854 g         7311 t
ORIGIN      
        1 ttgaggggaa gtacatatag ttgttgatat agttgctaat attgttagct aatttgttag
       61 taaaactgta tacgaattta gatagtaaaa aaacagtttg ttccttatat agaggcactt
      121 ttactactga ttaaatgtca gatatgctta caaatatact tataaatatg cttacaaaat
      181 tagctaatat ttccgttgac aaagctttgt tactattgtt aaactaaatt gactagcaaa
      241 agtgaaacat aaatttatta aataaatgta aaaattagga gaaatcaatg tcttatagag
      301 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
      361 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      421 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      481 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      541 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      601 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      661 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      721 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      781 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      841 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      901 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      961 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
     1021 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
     1081 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
     1141 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
     1201 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
     1261 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1321 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1381 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1441 gatgaatcga gaagcagaaa aaataataaa caaactcacc taatgaattt caagcgagtt
     1501 tgtttgttat ttttttattt aatctttgta tctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatgat cgctacgtgc gtccggcacg tcagtcacga tatcaaacaa
     1621 aaagtataca cccttcttca ttctagtttt cgcagcggga attttgaaat agttcttatt
     1681 agaatagtag agattgatta ataagctatc ttcgattgct aaaaagaaaa cttctgaatt
     1741 ccatacttta taaaaatctt tgataaatct attcgaaggg tcaaatttaa accataattg
     1801 tgtttttcct tccatcagca taaaagttca cctcaaaaag agtatacgaa cgaatgttct
     1861 ttttgtgaag gcggaattta atatactgaa taatagaaaa caagtacttg tgccaaatta
     1921 tgtgccaaaa aaattcgaat tcaacaaaat gtaaacaaat agaaaacctt ctatattaag
     1981 atttcctgca ataacaaaca caacagaaga cgtgtaatag ttagtcagga acgtacaaat
     2041 aacccctgta tcctttgcgg tacagggggt tattttgtat aagtagacat tgtagtttct
     2101 aaactgctat gtcctaaacg tttcgatacg ctaagtatat ttactccttg ataaagtaaa
     2161 atagatgcat gcgtatgtct tagtccatca ataaacagtc gaagagaaaa tagggaaaaa
     2221 ttgattacta aagaaaaact tactaggtcg acggtgtagt tgattttcat acttcaatag
     2281 attcgaatta aacgatttcg attggcttat accagtccta tccaacgaaa gatatatcgt
     2341 tcttaactct agcggtataa cttgaagctt tacgtaaagc caatgggaat gaactggaga
     2401 tgacttttta ttatttttag taatagctga tgggttaata cttacaactt tccttttcaa
     2461 agtaccatat aaaaaaacgg tggggttgtt tagcgaaata aaggatctaa gccaatagct
     2521 tagatccttt attctatgct ttatattatt ttttgcatgt gtgcgaaagt atactcaagc
     2581 ccaatcgcca tttcggaaaa tcggtactgt agagccatct tcacggattc cgtcgatatc
     2641 catcttgtca gatcctacca tgaaatctac gtgggtttga cttctattca atccagcttc
     2701 tgctaattct tcatcggaca tttctgtacc gcctttcaca ctgaaggcat aagcagaacc
     2761 tagtgctaag tgattcgatg cgttttcatc aaataatgta ttgaaaaaga tgatgccaga
     2821 ttgagaaata ggtgaagggt caggtacaag tgcgacttct cctaaacgac gcgcaccttc
     2881 atctgtatca agcagttttg ctaagacatc ttctccttgt tcggcagaaa aatcaacaac
     2941 ttttccatct ttaaaagtaa atttcatacc cgagatgatg gtgccagcat aactcagtgg
     3001 ctttgtactt gaaatgtaac catctactcg atgactgtca ggtgctgtga acacttctta
     3061 cgtcggcata tttgccatga atttttctcc acgagcatta tagcttccag cgccttccca
     3121 aagatggttt ttaggcaatc cgataatgat atctgtaccg ggagcagtat agtgaagggc
     3181 agaaaattgt tctcgattca attcttctgc tttttttgct aatttttcat catgcttctt
     3241 ccatgctaag acagggtctt cttcatagac acgagtcgtt ttgaaaatct gatcccataa
     3301 tgcctcaact tgtttttctt ctggcagttc tgggaagact tttgctgccc attgtttacc
     3361 agccgcagcc acgacagtcc aactgacttt atttgcttga gttgccttgc gtaaattcat
     3421 tagtgctttg ccattcgctg attgataaga cgctactcga tggctatcta caccagcaaa
     3481 tgcatcggga tcggcagaaa caacgctgat cctgcttgct cctttttcaa gccattcatc
     3541 cgcttgatcg attttagatt gtggtacatt ctcaatacga tccgttgcag catgtaaaag
     3601 aaattctctt tggatctggt cgtcagtcca ttgaacgata acctcagcgg ctcctagttt
     3661 ataagcttct tgtgtgatca atcgagcaag gggtgcctgt tccacgctga tctgtaaaac
     3721 aactgtgtgt cctttttctg tggctacgcc agtttctgca attaagcgtg catatttttt
     3781 tagaagttca ttaaaatcag ataacataat aaaaattcct cctcaccatt ttttctggta
     3841 actattagca tgataccatt taattatgat tcaaacaatg aggctttaaa taaaaaaagg
     3901 aggttatttt tttaaggtta agtttcatga tatatgttac tacttgctat ttcagcttgt
     3961 gaagaaaatc aaaaactaat tttgcatatc aaaaaaacat gttacaatga aattaatcaa
     4021 tggtggaagc gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat
     4081 tactagagaa cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg
     4141 atttactgcg agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga
     4201 gtttaaaaat atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca
     4261 atatgaagtg ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta
     4321 tatccatttt gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg
     4381 tggaggaaaa gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga
     4441 tccagcttat gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat
     4501 catagctact gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca
     4561 gattgaaaag atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga
     4621 aatcgattga atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa
     4681 taaggaaaag ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca
     4741 tgaatgcaat gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc
     4801 aagtatatta aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt
     4861 cttcttcagc attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg
     4921 caaaagcagc atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag
     4981 atccgcagac accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt
     5041 ctacgatctc atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat
     5101 ctgcctcctc gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat
     5161 ccagattttc aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc
     5221 tagcatatac gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa
     5281 ttatgaatta taccaaaaca tcattgaaaa gaaaataaaa cctaaagaca cctggggaat
     5341 gtcatttggc taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg
     5401 aaaatatgat tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt
     5461 tattagcaga tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg
     5521 atattgaggt atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg
     5581 gctttgaagg gtatgaatat gcgacttgta tcagtataaa tgatgaaatt tgtcatggat
     5641 tccctcgtaa aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt
     5701 tgaaaggcgg catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga
     5761 tcgaccgatt gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag
     5821 tagggaatcg gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc
     5881 tagcgatcgt tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag
     5941 cagttcctca ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca
     6001 cgatcgaacc tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga
     6061 ctgcgtatac aagagacggc ggactttctt gccaatatga acatacattg gctattacta
     6121 aagatggtcc aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt
     6181 caataggtac gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg
     6241 atgcgcttta ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct
     6301 gtcgtcgttg cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat
     6361 attttaccgt ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt
     6421 cctgagaccg tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca
     6481 ggaggcttgt tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat
     6541 gctttgcaaa ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc
     6601 gtccgtttct tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact
     6661 atcgttcttg ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc
     6721 gtgaacttta tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt
     6781 gtcatcatgt tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc
     6841 attccgggca cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc
     6901 tatgctaggt attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta
     6961 ctcatgcttt ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca
     7021 gttgttcaag aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa
     7081 tggttcaata aattgaaaac taaattttct cataaaaaaa agtagaaaca agagttctta
     7141 ttgtaaattt atatcagtaa tttataataa ttatgactct taattaaagt aggtgcccat
     7201 atgcttgttt cttttagtat ggttataaga ttttttctga caattttatt atcactgata
     7261 ttaacacctg tattcaaaat catttcagta caaacaggta tggtcgacaa accaaatgaa
     7321 agaagaataa ataaagttcc aatgccttca gcgggcggac tgcctatctt tatttcattt
     7381 gttatatcga ctttattctt attccgtaaa attatccctc aatcgtatat tgtaccgatc
     7441 ttgattgctt ctttagtaat catagtcaca ggagtgctcg atgataaata tgagctgaca
     7501 cctaaacaaa aaagtatagg gatcttgatt gcttctctta ttatttattt tgtagcagat
     7561 atacgtattg attccttcac gcttcctttt attggatata tccaactagg ctggcttagt
     7621 tttcccgtaa cgattttttg gatcttcggt atcacgaatg cggtcaatct gattgacggt
     7681 ttggatgggc tggcggcagg gatttcattg atcggtttaa ttacgatagg aatcattgga
     7741 tattttttcc tccatgcttc tacagtgtat attccagttg ttattttctg tcttgtagca
     7801 agtattatcg gtttttttcc ttacaatttt tatccggcaa agatttattt aggcgataca
     7861 ggagctctat tcctagggtt tatgatggcc gtcctttcac tacaagggct gaagaacgtg
     7921 acttttgttt catcgatttc tttgctgatc gtcatgggag tgccggtaac agacacgttt
     7981 tttgctatca ttaggagaaa agcaaaccgt gtttcttttt ctacagcaga taaaaaacat
     8041 cttcatcacc gactaatcag tttaggcttt actcataaag gtgctgtcct gacgatttat
     8101 gcgatggctt tgatgttttc tttcacagct atggtcatga attatactgg aagaatcgga
     8161 acgatcatat tgattattgc catgttgttt gctgcaattt tattatttga attgattggt
     8221 ctgatcaatg agaaacatca gtttatttta aaaacattgc gatttttagg gaataaagag
     8281 taccgtacgc aagtaaaaca gaaatatttg aagaaatgga accgtcatat agatgaataa
     8341 caaattaaac cagccgatcc ttattagtat tgtgacggca aacagtgata aaatttttcg
     8401 gacactagat aattttattt caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt
     8461 tgacaacaat tcacttcccg agtacaaaaa aagactaaca gagtatagga aatatcccta
     8521 catcgatatc tattttcatg atgaaaattc cggatttggt tatggacata atcacaatct
     8581 gatagctagc gattctcgct atggcattat ttgtaaccca gatattttag tggatgaaga
     8641 gacagttaca gcattggtct tgttattgaa agaacatccg gaatgtgcga tgttagcacc
     8701 taagattctt aatgaagatg gaacaactca gcacctcatc cgtgagcagc tggctgtttt
     8761 tgattacgtt ttgcgctttg tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact
     8821 ggctgtgttt gaatgccgag gattgcctac tgatgctaat agttatgtac ggatgatctc
     8881 aggtagtttt atggtagctg atattgataa atttaaagag ataaaggggt ttgatgagcg
     8941 tttcttcatg tactttgaag acaacgactt gtgtttgagt tttgaaaaag caggttacaa
     9001 gttattgtac acaccctttt atgcagttat ccatttttac gggaagggtg cgcatcgaaa
     9061 tgcaaaactg tttcgcgtgt ttttgacttc tatgatgaaa tttttcaata agtgggggtg
     9121 gcgttttttc tgatgaaacc agaaatatta gtagtcgttg tgctttatca gcaactattc
     9181 agtcaatctc cagcttatgg accattaagc aaagcactta gcgaaaagca aattcagctt
     9241 attatttacg ataatagtcc tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc
     9301 gtttatcatc atgatccgca aaatcctggt ttagcggtgg cttataattt tgcgttgtct
     9361 caagcagatg aaggaacacg ttgtctcgtc actctggatc aggatacgag gctagtcgac
     9421 gattattttg aactattgcg taaagtaacc tttacagatg aatgtgttgc tgcagttccg
     9481 atgatttttt ctgggagccg acaagtttct cccctatatt cagatcgtta tatcaatcgt
     9541 acagctcaag cagtagaagt tgaaggccca acagctgaac gaatcatggc aatcaattca
     9601 ggtgttgcct ggtctgtcaa atttctaaaa aagattggcg ggtttaatcc tgctttttct
     9661 ttagattttt tggatcattg gctgttttgg aaagtggatc agttggaaaa aactgtggag
     9721 atccttcctg tacgaatgga acatgatctt tcggttttag actatgaaaa agtttcaagt
     9781 aatcgatacc gttctatttt acaagcagaa aatcgatttt atcatgaata tgatcaaagg
     9841 catttatcca gtcaccgacg acaattattg ttaagaacag ctaaacagtt cttgaccgtc
     9901 aaaaaccggc atatctggcg gatgactttg cgctcatatg ttaagaattg gaaggtgtga
     9961 attcgtgcgt tcggtttgta tagctacctt taatggaggc agatatttaa gagagcagtt
    10021 agatagtatt ttatctcagc tttcagcaga agatgaagta gtcatttctg atgatgggtc
    10081 agtagatgat acatgggata tattaactga atacgcagaa aaagataagc gaatccagct
    10141 tttttcgggg cctcgtcaag gattgatcgc taattttggt tatgcgatcc agcagacgaa
    10201 aggagatcta atctttttgg cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa
    10261 gatcactgac tattttgagc agaatccgga tcagctagta gtagtttctg atttaatcat
    10321 tgtggacagc gagctgcaag agatccatga ttcgtatttt tcgtttcgaa attccaaaga
    10381 aggatggctt aataatgtga taagaagtca ctatattggt gctggtatgg ctttccggtc
    10441 ttctttaaaa cccgatattt tgccgatccc gtcagaagtg ccgatgcatg atatgtggat
    10501 tggtttgctg ggaggaaaga agactgggtt cctaagagaa ccgttaactc tgtaccgaag
    10561 acatgattta aacgcgagtg agattgaaac acattctaaa ttacggcaaa aaatttcttg
    10621 gcgtgttcat ctgattacgg cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat
    10681 gtttaaatcc ttaatatttc catgacaaat ataacaattg atgagataat aacaaagtga
    10741 aatttgaaat caaaaaggag agcagatatc catgaaggga atcattcttg ctgggggcag
    10801 cggaacacgt ctgtaccctt taacaaaggc aacatcgaaa caattgatgc cgatttatga
    10861 caaaccaatg atttattatc caatgtctac tctgatgttg gcgggaatca aagaaattct
    10921 gattatttca acgccacaag atacaccacg tttcaaggaa ttatttggaa acggaaatga
    10981 tttaggactg cagatcgaat atgcagtaca agaaagtcca gatggattgg cacaagcgtt
    11041 tatcattgga gaagaattta ttggagatga tagtgtctgc ttggtattag gggacaatat
    11101 ttactatggt ggcggtctgt ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc
    11161 gacagtattt ggctatcatg tcaatgatcc agaacgcttt ggtgtagtag aatttgatga
    11221 gaatatgcaa gctttgtcga ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt
    11281 aactggcctt tatttttatg acaatgaggt aatttctatc gctaaaggta tcaaaccttc
    11341 agaacgtgga gaactagaga ttacggatgt caataaagca tatttggata aaggaaaact
    11401 atccgtagaa cttatgggac gcggatttgc ttggcttgat acaggaacac atgaatcatt
    11461 gcttgaagca tctaccttta tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg
    11521 tttggaagaa attgcttacc gtatgggcta catcgataag gaacaattgc tggcccttgc
    11581 acagccattg aaaaaaaatc aatacggtca atatttattg aatttggccg ctgaataagg
    11641 agtccttaca gatgaaagta acagatacaa aattaacaga tgtcaaaatc gtagaaatgg
    11701 acgtctttgg cgatcatcgc ggtttcttca cagaaagtta ttcaaaagca aaatttgcag
    11761 aacatggatt gaaatatgac tttgttcaag acaaccattc actatcagct gaagctggtg
    11821 tccttcgggg gcttcatttc caaaaaggag aagctgcaca gacaaaattg attcgggtag
    11881 tcactggagc agttttagat gtagtagtgg atatccgcaa aggtagcccg acttatggtc
    11941 aatgggacgg atttatctta tctgaacata atcatcgaca gttgcttgta cctaaaggat
    12001 atgcccatgg attcgttact ttgacaccaa atgtgaactt cctttataag tgtgataatt
    12061 actataatgc agaagcagat gggggcatcg catttgatga tccagattta gcgattgatt
    12121 ggccaattga tccatcaaga gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa
    12181 aagaatttga agcagaaaat ccatttgttt acggagaaat ctaagaatta aggagaaatt
    12241 ttcttatgaa aaacatcatt gttaccggag gtgccggatt catcggctct aatttcgttc
    12301 attacgtggt aaacaatcat ccagaagtgc atgtcactgt tttggataaa ctgacttatg
    12361 caggaaacaa agagaacttg gccggacttc ctagcgatcg cgtagaattg gtcgtaggag
    12421 atgttgcaga tgcagaatta gtggaccgtc tagtaaaaga agcggacgca gttgttcatt
    12481 acgcggcaga atcccataac gataattcat taaaagatcc tttcccattt gtacaaacga
    12541 atatcattgg tacgtataca cttttagaag cttgccgcaa gtatgatgta cgctatcatc
    12601 acgtatctac tgacgaggtt tacggcgatc ttccattacg tgaagacctg ccaggacatg
    12661 gggaaggcga aggagaaaaa ttcactgcgg aaacaccata taatccttca agtccatatt
    12721 cttctacaaa agctggttca gatctgttag taaaagcatg ggtgcgttct tttggcttac
    12781 gtgcaaccat ttcaaactgt tcaaacaact atggtcctta tcagcatatt gaaaaattta
    12841 ttcctcgcca agtaacgagt atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa
    12901 agaatgttcg tgactggatc catacgaatg atcattcttc agcagtgtgg ctgattttga
    12961 cgaaaggcag aattggcgaa acctatctga tcggtgcaga cggtgaagaa gataataaga
    13021 ccgtgatgga attgatctta gaaatgatgg gccaaccaaa agacgcatac gaccatgtaa
    13081 acgaccgcgc agggcacgat ttgcgttatg caatcgattc gacaaaattg cgagaagagc
    13141 taggttggca gcctgagttt acgaacttcc gtgatgggtt ggctgacacg atcaaatggt
    13201 acgaagaaca tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca
    13261 aaaatggaca ataatacaga ggaaatttca ctgtattaat ggaaaaacac atgtgaggca
    13321 ggcgctcgcc tgtctctttt ttaaaataaa aatcaaggag cggataacca tatgttttta
    13381 ttaactggag gaaatggaca attaggtaca gaattgcgcc atttattaga tgaaaaaaat
    13441 ctgccatatg tttcaacaga tgcaaaagac ttggatatca cagatgctga gaaaacaatg
    13501 gcttatatta cagaattaaa acccgatgtt attttccatt gcgcagctta cacagcagta
    13561 gataaagcag aagaagaagc aaaagaatta gatgagaaaa tcaatgtcga tggcacaaga
    13621 aatgtagcac ttgcagcaaa agctgtgaat gcacaattcg tctatatcag tacagactat
    13681 gttttcgatg gaaaaaacaa aaatgtagaa tacgaagtag acgaccaaac gaatccacta
    13741 aatgaatatg gtcgtacgaa attattaggc gaaaaagcag tagaagagat tttagaagac
    13801 tattatatca tacgaacttc ttgggttttc gggatctatg gacacaattt cgtcttcacg
    13861 atgcaacgcc tagcggaaac ccgcgacaaa ctgactgtag taaatgacca gtttgggcga
    13921 ccaacttgga cacgtacttt ggcagaattt atggtatatg tcatcgaaga aaaagcacca
    13981 tttggtattt atcatttgtc gaacgaaaat agctgttctt ggtatgagtt cgcaaaagaa
    14041 atattgaaag atacagatgt agaagttgca cctgttacgt cagaagaatt tccgcaaaaa
    14101 gcaacacgtc cgcagtattc agtcatgagc ctgaaaaaga cagaagcgtt aggttttgtc
    14161 ataccaactt ggcaagaagc acttgcgcaa atgctggaag ctgccaaaaa aatgaataag
    14221 taatttcctt tttatcaaat agaatttgga gcatgatatg gaaaaacaaa caagaagtgc
    14281 acgacgaaaa gaaaagccaa aagcgaatca ggcagattcg aatttggtgc ttgacctgtt
    14341 tctaaaactc cgctatctta ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt
    14401 aaacggaagt tcacttggtg tttgggataa atatgtgtcg caaagagacg atgggaaaaa
    14461 aactgatgtg atttttggac agaatcggga agtgcggtca gacgaatggc tggtgcagac
    14521 acctttttac ctctcacaag ctgaagagga cttttcgttg gtgaacgagg attattcatt
    14581 aaacggacaa aacatgatca ttgcgtataa ttctcctgta aaggatatta cggttatcgg
    14641 aaaaccattc aactggggat tctttttcct cggaagagat cgaggacttt ccttttattg
    14701 ggcgatgaaa ttagtcgtca tggtcttgct tggattcgaa gtactgatga tattaacgaa
    14761 gaggaaaaaa gctctatcgc taatcggtgc atttgcgctg acattttctc cagcagtcca
    14821 gtggtggttc atgcaacatg tgggcgattt gattttcttt actttgggac tgatgattgc
    14881 tttttatcat tatttctaca atcatgataa aaaatggcta cgaacgttga tgatgctttt
    14941 ggtggttatt ttcggtattg ggtttatttt agtgatttac ccagcccatc aagtgatgct
    15001 ggcgtacttg ctgatttttt attttgttgg cctgcttatt tactatagca agaaagtttc
    15061 atgggatctg ttggatgtag tgttgattgg aggggcagtt ttatttattg gcggagtcat
    15121 ggttcatttc tggctaacgt caaaagacgc attgttagct tctttgaata ccttatatcc
    15181 aggaaaacgg gtaagtactg gaggaaagtg gacgattggc gaattttttt ctttccttac
    15241 aaattggaaa attccttttg aagatatcaa ctattcgaat aactctgaag tggccctgtt
    15301 ctatcacttt tttccaactg tattcctagc aagtccattt gtgttatttg gcaaaaaaga
    15361 tagcgaacaa aagttactgg gacgtatttt gatgattttt tgtctgtttt ctatcttttg
    15421 gattaccgtt gggttgccaa aatggctagc agaaatcact ctgctgtctt atgttcctcc
    15481 attaagagcc atccttactt ttagttttgc ggcttgttta ttatcgatct ggtttatcgc
    15541 ttatatttgg agagaagatg ttattcctat ttggtataaa ttcattttgt tggcagtaaa
    15601 tgcatggtct tatttctatg cgattacgca ttcgaaaatg gataattatt tttcggattt
    15661 tgaaaccatc gcagttgctg tgttgggaac agtgatttta gcttttgcat tatttggctg
    15721 gagacgcttg ttttacctcg cttttgtcgc cttagttatc gtatctggct ttttcgtcaa
    15781 tccagtcgta gaaggtacag gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa
    15841 aatcgatcaa caagatcctg gtaaagtttg gttgtctgaa gatgaattat ataacttcac
    15901 cccaacattg ggagtgaaat ccttcaatac agtacgcttt tatccagata tagctgcatg
    15961 gaagaaaatc gatccgaaag aagaatacga gaagtattat aatcggtatg ctcatacaag
    16021 agcttttatc gctaaggaag atacaaagtt cattttagat cgtccagata tgttttcggt
    16081 cacgttgaat tttgaagacg cagaaaaatt agggatcgac tatgtgatca gtaaacgacc
    16141 attaactgat tacaaccaat tatatgaagc gcagttcacg cagctatatg gaccggataa
    16201 agacggttat atgattttta aagtagaata tccggattat ccagatgtac cacaaacaca
    16261 aactcaggaa aatcagctag tcgtacagta ataggctagc tgagaataat cctgaaatat
    16321 tagtagaaag gagagtgaag ataattcaag caatcgtaca aaaatttgtc aacaaaatga
    16381 gtgtcggttt cttgcttttg ttgctgacgc tagtcttttt tgtttggaca gcaggggtag
    16441 gttttccagc aactttgttt atatataaca atagttcatt acttatcgct tttagtgtgg
    16501 ctattttgct cattttaaat gtttataaag caaaaggcgt cgattttctt tatctaggtg
    16561 ttgcgcttgc ccttttcatt ttcttttctt actttcggga attaagaaat gagtctttat
    16621 ttggagactt actgtttcct ttgattattt tattttgttt agtaattaaa tggatcgagt
    16681 ggacaaaatg ggatcgcggt atttatctga ttgtctttac ggtcttcctc ggaatcacgt
    16741 tatatcgtgt atttacagag atccaagtac cagaaggaca aagcatctgg gctccaggca
    16801 attcgctttc tgatatttgg atcaatacga atacaatcgg aagttctttg atgactcttg
    16861 ctttattgat cagtggattt gccagttctt ttgaacgatg gtatgttcga atcatcggtg
    16921 ggatagcagt cgttgcagcc tttttaggta tttgggtctg ccaatctaga ggtgcattag
    16981 tcgcgttgat tgtttttgcg atattggatc ttttacctaa atcgttgatg cgtgtcattc
    17041 gtgcgccatt tattgcctac acggttacga ttcttttagc tttgccgatt tcttatctgg
    17101 cggctgtctc tgaaaaagtc aatttgttta ccggtcgaga agatatttgg cataaattct
    17161 atcagacgct aggagaaaaa tctgaacaag ttttactagg aatgaaaaca tttatcttcc
    17221 agcgaggaaa ccaattttta ggaaaccaca atagttataa ttctattttg aatatctatg
    17281 gattgatagg atttgggatt gctgctttgc tgcttatcct ttttattggt cgcttaacgt
    17341 tgaaagcaga tttatccaac gggcagatga cttttatctg ggcctttttt gcggtgatga
    17401 tgcagtcatt tatggaggat acattgactt cataccgatg ggttccgatt atttatatcc
    17461 tgttggctat ggccgttcat cgatatgatg aaccagaagt tacggaggaa ttctatgtta
    17521 tggaagaggc atatgacgat atgacttatg atgatacatc ttatgaggaa caaccagata
    17581 gcgctcattc ttccaggatc caacgctatc attgataggc acaaaatacg agagaggctg
    17641 tgacaaccgt cgcagccttt tttggtttat tgcaattgtc tagcatcttc tgtaaaatag
    17701 aaacgttaga gaaaatcttg tatcatagaa aattaagaaa gaaataagaa cgcagctcgg
    17761 taccaaaaat atggtaaaat ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac
    17821 acaaatgttt aaagatttgt atttatttat gaaggacatt tatcagaaca gaaaattact
    17881 gctacagttt tcgatcaatg acttcaaatc aagatatgca ggatcgtttt taggaatctt
    17941 atgggcgttt atcaatccgc tatttactgt attgatttat tggctggtat ttggtgttgg
    18001 actgaaagca caaatgatcg atgcaaaata cccatttatc gtatatttag ttaccgggat
    18061 gattccctgg ttcttcttct cagatgcatt tgcatcaact acggttgttt ttcgggaata
    18121 tacttattta gtaaagaaag tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct
    18181 atccaatctg tacacccatt tattcttcat tctgattggc atagctgtcg cgcttataaa
    18241 tggtatatat ccttcagcaa tgtctttaca gctgatttat tatttatttt gcatgtgtgc
    18301 tttcttgaca ggattgactt ggctgacggc atcgatccaa ccatttttac ctgatatcat
    18361 gcaattaatt acgatcgtgc tgcagttgat catgtggaca ttaccgatat tatggagccc
    18421 taatcagttt gattcaggtc ttgtaagcat attgaaatta aatccgctgt actatgttgt
    18481 tcaaggttat cgtgagtcat ttttaagtga agcttggttc tgggagcatg gaacatatac
    18541 tttgtatttc tgggttttca cgttagtaat gttcgtaatc ggctctgcag tgttccgtag
    18601 attgaaacca catttttcag atgtgctgta aggagaatag ctatgacaga atatgcaatt
    18661 agactaaaag atatcacaaa atcttataat atgtacgcaa aaccttcgga tcgatttcgt
    18721 gaagccctca atccttttaa gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg
    18781 aatgtagaaa taaaaaaagg tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa
    18841 tctacaatgt tgaaaatcat tacgggagta ctgacaccaa catccggcac gatggaaatc
    18901 gaaggaaaaa tctcagcttt gctagaacta ggatcaggat tcaatcctga gtattctggc
    18961 tatgaaaata tctatttaaa tggaatggtt ctaggatttt caagagaaga agtcgatgaa
    19021 atggtcgatg atatcattga atttgctgac atcggcgacc atatttatca acctgtaaaa
    19081 acctattcaa gtgggatgtt cgttcgtcta gcttttgctg tagcgatcaa tgtgaatcct
    19141 gatattttga ttgtggatga agcattggca gtaggagatc ttgaatttca actaaaatgt
    19201 atggaaaaat ttacagaaat caagaactcg ggaaagacga ttttattcgt ttctcatgat
    19261 attagttcga ttcgccgttt ttgtgatcgt tcctattggt tgaaaaatgg aaaagttgtc
    19321 gaatatggtg atacgatgga agtaacgacg aattacgaaa actttttgaa gaaaaaatca
    19381 gttaaaacag tagatcgaaa taaaaaccaa gtagaacgct tcgcagctcc agatatcgta
    19441 gacgtgacga aagccgaatt gttggataaa gataaaaatc cagtggatat gctggaacaa
    19501 ggagaaaaac tatacgttaa agtaacctat gaagtaaaag acgatacaat caaaaatcca
    19561 gttttaggaa ttgctctgcg tacagtcgac aatttttatg tgtgcggact caatactcta
    19621 ctagatggta tcaagatccc ttggaaaaaa ggtgagaata tcttttatct ggagtatgaa
    19681 aagttaggtt tgttagctgg tgaatattat tttgacgttg cggtctttga agaaaatgca
    19741 acggttcctt tggtatacaa gacaaaatac atgaacttgt ttgtcagcgg ttcttatatc
    19801 ggagaaggca tcgtggtctt agaccataaa tgggaagaag ggactcatag caatgaaata
    19861 tgattttgaa atggacctag atgaacaaag cagtgtggga aaaattgccg cacagatcaa
    19921 accaggaagt aaagttttag agtttggtcc tggaaacggc cgattaacga aacatttgat
    19981 cggagcaaaa caatgtgaag tgagcattgt cgagctagat aaggaattgt tcgattttgt
    20041 cagcgagttt gcccaagatg gattttatgg agatatcgaa agttttgaat gggcaaacta
    20101 ttatgctgga caaacatttg attacgtttt gtttgccgat gttttagaac atttggtaga
    20161 tcctggaaaa acgttgaaga aagttagaga atttttgaat gaagaaggag aaattctaat
    20221 tacattccct aaccttgcgc ataattctgt catgattgat ttgttcaata atcaattgcc
    20281 atgggcttct tatggtttgc tagatgaaac ccataattct ttttatactc atgatggctt
    20341 ccaaaaagtt tttgaaaaag caggattata catcaatatt gaagattatt tgtacttagc
    20401 tgtaggtgat acagaattaa aatcaactta tgaagaattg ccggaagctg tacgttatga
    20461 tttcaaaatg cgaccatttg gcgaagtcta ccaatacttc ttctcattga tgaaacatcc
    20521 agtagcacaa agttccattg cgcagccgca aaattctaat tatgtgaaag tattagaagt
    20581 aatccagcaa acgaaacaag atgaaataat tcaacaaata ccattcaata atttcacagg
    20641 ggaaaatgag acactaagtt tccatgtatc agaattagca gaacgaatgg tgtttcgctt
    20701 cgcgcagcaa cctagcttta tcgaattcag cgcagaagct gctggagaaa aactcacatt
    20761 tatcgattca aatgctgtag tcaaaacagt aaatgattgt tatttgtttg atggtaaaga
    20821 tttaccagag ttctttttaa cggatattgc agggaaagaa gtgactatcc attgtcacta
    20881 tcgttttatc ggagaattga caccaacaat gaaagaattg ctggaaacaa tccgtccaat
    20941 ggctgaagtt acaaagcagc tttctgagaa aaatgatgaa ttagaaagag aaaatcatta
    21001 tcttattgag aataatacaa gattagatca gacgttgaaa acaaccataa atcgctattg
    21061 cacgttgttg gaaagtgatg aatggacaat caaacataga ttagggcgac gtaagaaaga
    21121 aacatcgaaa aaaatccaag aaaaagagct ttctctatgt attgacgaaa aaatctggga
    21181 tgcagaaaca aagatattga aaatcatcgg gtggggaatc gctaattcgg atcgccaacc
    21241 attgtcctat aagttatcag ccgaccaatc accatttttt gaagcaattc ctgttttacg
    21301 agaagaagtc aatcaagcaa aacagctagc tgaaggagca aaagcaggat ttgaactgcg
    21361 gatcctttgc gagaaggaac gttcattctt agttgaagca gtggctcaaa atggtcaatc
    21421 atggatcatt gaaatgtaaa taatgattaa cttataaaga taaggagtaa acgaatcgtg
    21481 caaaaaaaag aaattgccgt atttatcgat caaatcactc gtgaacgggc cactggcgat
    21541 ttgcttattg tgggctgggc aattgatgaa gtgaccaaag aaatccctac gataaaggta
    21601 gaaaaagaaa atgtgattgc tgaagcaaca catgtcgtaa gattggatat caatcattta
    21661 tataatcttg atgttaagac ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga
    21721 ggaaaagcaa tcttagactt ccaaacagca agacatcaaa atggcatagc tgtgaaatta
    21781 aacggtaaat atccttatga tgacggcatt gaatcttcat gggaaagaaa aaaaagatta
    21841 ctgaaaaaag ggataaatta tgcaaggact catggcgtaa aaaaagcaat ccgccgggtc
    21901 aaactggaat tgaaaccagg atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa
    21961 cctgatctga aagagcaaag gaaagaagta caaggatttg cctaccgccc attgatttcc
    22021 atacttatgc ctgtctataa cgttgaaatc aaatggctcg aaaaatgcat tgattcggta
    22081 cttgatcaaa cgtatgatca ctgggaacta tgtatcagtg atgatgcttc tactgatcca
    22141 gctatccgaa agtgtctaga atcctatcaa gcaaaagatg atagaattaa agtcgttttc
    22201 cgacaagaaa atggacacat cagtctggca actaattctg cattggaaat ggcagaagga
    22261 gagtttatag cgctcttaga taatgatgac gaattacctc catttgcctt atatgaagtg
    22321 gcaaaagtgc taaacgtaca tccagaactg gatttgatct acagtgacga agataaaatc
    22381 gatgcagatg ggaatcgctt tgacccgcac ttcaaagcag actggtctcc cgatacattg
    22441 atgggaaata attatatctc tcacttaggc gtatatcgga caagcattgt taaggaactt
    22501 ggcggtttcc gtaaaggata tgaaggctct caagattatg atttggttct tcgtgtgaca
    22561 gaacaaattc ctgcagaaca catttaccac attgaccgtg tcttgtatca ttggcggacg
    22621 atcccgggat caactgcaag caatggagaa gctaaaagct acatctatga ttctggagtg
    22681 aaagcattga cagatgctct atctagaaga aatatcaagg gaagcgtaca tcctggcaga
    22741 atttctggtt tttatgaaat cacttatgat gttttgcaag aagacttggt cagtgtgatc
    22801 attccaacta agaatggcta tgaagatcta aaaacttgtg tggattcgat catcgaaaaa
    22861 acgtcttatc caaattatga aatcattatt gcagataatg gaagtacaga tcctaaaatg
    22921 caagaattat ttgcagaata caagcatcag ctgaaagacc gatttatcgt cgaattaatt
    22981 gacattccat tcaattattc acgtatcaac aatctggcag cagaaaaagc aaacggcaaa
    23041 tactttttat tcttgaataa cgatacagaa gtgattgaac ctgactggat gacagcgatg
    23101 gtttcttatg cacagtttga tcgaatcggc tgtgtaggag caaaattatt ttatccggat
    23161 gatacaacgc agcatgcagg tgtattatta gggatcggtg gcgttgcagg acatgcattg
    23221 aataactatg atcgaacaca ttgtggttac tttggccgat tggtcattga cgtcaattac
    23281 ttagcagtca ctgcagcttg tatgatggtc aaggcagctg acttcaatgc tgtcaatgga
    23341 tttgatgaaa tattagaagt agcattcaac gatgttgact tgtgcttgaa agtttatgaa
    23401 ctgggtcgtt acaatgtcta tgcacatcaa gcagaattgt accatttcga atctaaatca
    23461 agaggttatg aagatacacc agaaaaacaa agacgttttg ctggggaaat caaaaaaatg
    23521 caagataagt ggccttctta tattgctcat gacccatttt ataacgataa tctaactaaa
    23581 gaaggaatcg gcgatttttc gttgagacct gattgattaa aagaactgta ttttcatttt
    23641 tattaatgaa aatacagttc ttttaattta a
//
LOCUS       DAZKCW010000040        23271 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000040 DAZKCW010000000
VERSION     DAZKCW010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.040"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..699
                     /locus_tag="ACG84Z_001847"
     CDS             <1..699
                     /locus_tag="ACG84Z_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162660.1"
                     /translation="TKNTILYNVAFILLNLLISVVFAIIMSELRNKRLVKVYQTMSLL
                     PYFLSWVIISYFVYAFLSPDKGIFNQWITGHGGEAVNWYNEPKYWPFILVFIGTWKGI
                     GYNSIIYFASVMGIDPTYYEAAMVDGASKWQQIKHVTIPQLIPLMTILTILAVGNIFR
                     ADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTSTGDFGMTAAAGLYQSVVGFVLLMIT
                     NTIARRFDSDSALF"
     gene            711..1631
                     /locus_tag="ACG84Z_001848"
     CDS             711..1631
                     /locus_tag="ACG84Z_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162661.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            1672..3129
                     /locus_tag="ACG84Z_001849"
     CDS             1672..3129
                     /locus_tag="ACG84Z_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9162662.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            3474..4088
                     /locus_tag="ACG84Z_001850"
     CDS             3474..4088
                     /locus_tag="ACG84Z_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFP9162663.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            4081..5805
                     /locus_tag="ACG84Z_001851"
     CDS             4081..5805
                     /locus_tag="ACG84Z_001851"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9162664.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            5802..7253
                     /locus_tag="ACG84Z_001852"
     CDS             5802..7253
                     /locus_tag="ACG84Z_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFP9162665.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(7726..9879)
                     /locus_tag="ACG84Z_001853"
     CDS             complement(7726..9879)
                     /locus_tag="ACG84Z_001853"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFP9162666.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(9881..10927)
                     /locus_tag="ACG84Z_001854"
     CDS             complement(9881..10927)
                     /locus_tag="ACG84Z_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9162667.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            11077..12366
                     /locus_tag="ACG84Z_001855"
     CDS             11077..12366
                     /locus_tag="ACG84Z_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFP9162668.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            12379..15081
                     /locus_tag="ACG84Z_001856"
     CDS             12379..15081
                     /locus_tag="ACG84Z_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFP9162669.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            15066..15923
                     /locus_tag="ACG84Z_001857"
     CDS             15066..15923
                     /locus_tag="ACG84Z_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFP9162670.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(15994..16851)
                     /locus_tag="ACG84Z_001858"
     CDS             complement(15994..16851)
                     /locus_tag="ACG84Z_001858"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFP9162671.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            17062..19233
                     /locus_tag="ACG84Z_001859"
     CDS             17062..19233
                     /locus_tag="ACG84Z_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFP9162672.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            19301..19642
                     /locus_tag="ACG84Z_001860"
     CDS             19301..19642
                     /locus_tag="ACG84Z_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFP9162673.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(19918..21672)
                     /locus_tag="ACG84Z_001861"
     CDS             complement(19918..21672)
                     /locus_tag="ACG84Z_001861"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162674.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(21683..22519)
                     /locus_tag="ACG84Z_001862"
     CDS             complement(21683..22519)
                     /locus_tag="ACG84Z_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFP9162675.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(22521..23204)
                     /locus_tag="ACG84Z_001863"
     CDS             complement(22521..23204)
                     /locus_tag="ACG84Z_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFP9162676.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT         7653 a         4159 c         4783 g         6676 t
ORIGIN      
        1 actaaaaata caattttata taatgtagca tttatccttt tgaatctgct gatctcagtc
       61 gtatttgcaa tcattatgag cgagttgaga aataaacgac tcgttaaagt ttatcaaacg
      121 atgtccttac taccttattt tctatcttgg gtcattatca gttactttgt ttacgctttt
      181 ttaagtcctg acaaaggaat attcaatcag tggatcactg gacatggagg agaagctgtc
      241 aattggtata atgaaccgaa atattggccg tttatcttgg tgttcattgg tacatggaaa
      301 gggattggtt ataacagcat tatttacttt gcatctgtta tgggaatcga tccgacttat
      361 tatgaagctg ctatggttga tggagctagc aaatggcagc agatcaaaca tgtgacgata
      421 ccacaactta ttccactaat gacgatttta acgattttag ccgtaggaaa cattttccga
      481 gctgattttg gcctgtttta taacattcct aggaattccg gtgcattata tgatgtgact
      541 caagttttgg atacgtatat ctacaatggc ctgacatcca caggagattt tggtatgacg
      601 gctgctgcag gactttacca atcagttgtc ggctttgtct tgttgatgat cacaaatacg
      661 atcgcccgac gttttgatag cgattctgca ttattctaag gaggaaaaaa atgaaaaaaa
      721 agaaagtgga gagagtccaa gtccgctctt tcaataagac ggctaatttt ttctctaata
      781 taatgattgc actctttgct atttcctgta ttttgccatt tatatttgtt atcgccatct
      841 cttttaccga tgagtccata ttgtcgactc acgggtacag tttttggcca gaaaagttca
      901 gtatatttgg ttatacgtac ttgttcgacc agatgcagga taaaattttc caagcgcttt
      961 tcgtcactgt acttgttact gttttaggta cactgatcaa tagcacggct acttctttat
     1021 atgcttatgc gatttcacgg tcaaactttc cattccgtcg tttttttacc gttttttgtt
     1081 tgattacgat gttgttctca ccagggatgg tggccaatta tcttgttatg acaaatcttc
     1141 ttcagttaaa agatacgatt tgggcattga tcttgccaat ggctgtcagt cccttcaata
     1201 ttattgtgat gcgcacattc tttaaacgtt cggtctctga ttcgattatt gaatcggcac
     1261 ggatcgatgg agctagcgaa ctgcgaatat ttgttcagat cgttttaccg ttagctgttc
     1321 caggtattgc gacaatcagt ttatttgccg cattgggtta ctggaatgac tggttcaatg
     1381 ctttactata catccaagat gataagctag ttccactaca gtatcttttg atgaaaatcc
     1441 aaagtaatat tcaatatctg acacaaaatt caggagcagg aagccaattg acaggcggat
     1501 tagcctcagt tccaggagaa tctgccagaa tggcgatcgt agtcatctcg acgttgccta
     1561 ttgcgatcag ctatccattt ttccagaagc attttgtcaa aggtctaaca atcggcggag
     1621 taaaagaata aagaaacaaa aatataaatc ataaaattag gaggaagaaa aatgaagtta
     1681 tggaagaaac tagcctttac aggtgtttca gcgttgttgt tgggaacatt agcagcatgc
     1741 ggaggttctg gttctaaaga ccaggcagaa gctagcaatt cggacacttt gcagatgtat
     1801 caaatcggag ataaaccaga taatttcgat caattgatgg aagtagcaaa caaacgaatc
     1861 gaaaaagaga tcggtgtaaa agtcaatatc aattacattg gctggggcga ttacgaaaag
     1921 aaaatgaacg tcatcatttc ttccggggaa aattatgata tcgcctttgc gaacaactat
     1981 gtttccaatg cccaaaaagg agcctttgct gatttgactg aattagcgcc taagtacgct
     2041 gaaaaagctt ataatgattt agatgaagca tatattaaag gaaatctggt caatggaaaa
     2101 ttatatgctt tcccagtcaa tggaaatgtc tttgctcaac aagtacttac ttttaacaaa
     2161 gctttactag ataaatacga tctttcaatt gatggaatcc aatcttacgc tgatgcagaa
     2221 aaagtcttga aggaattcca tgaaaaagaa ccaaacacgg cagcttttgc cattggacaa
     2281 ggcttcaaag tccaagggaa ctttgattat cctttaggga atacgttacc atttgctatt
     2341 gatctggatg gagatgattc gaaaatcatc aaccaatacg ataatgaaac gtatatcgga
     2401 ctgttacgta caatgcatag ctggtacaaa caaggactca ttccaagtga cgctgcaacg
     2461 agcaataagg attatccact agaaggaaat acttggctaa tgcgtggaga aacacaagga
     2521 ccgtatgatt atggcgatac aattttgaca aatgcagcaa aacaagaact tgtctcaaaa
     2581 gcaattactg ttccactaaa atctacagct caagcacaaa tggcaaattt tgtcgtatca
     2641 aatacttcaa aaaataaaga aaaatcagta gaacttctag ggctgcttaa cagtgatcca
     2701 gaattattga atgggcttgt ttgggggatc gagggagaag catgggaaaa agtcgatggt
     2761 tcagatgata aaatcaaatt gctagatggt tatcagccaa atacacatat gtctgcttgg
     2821 aatacaggaa acaacaagat tctatataca caagagtcta ttacggatga catgattgcc
     2881 aaacgtgatc aatcgattgc tgatgcagaa acttcaccga ttttaggatt cagcttcaac
     2941 actgacagtg tcaaaacaga attaagtaat atttctaatg tcatgaatca atatttagat
     3001 ggattgaata cagggactgt tgatccagat gaaacattac cgaaattgaa agacgctttg
     3061 gacaaggctg gctatgataa ggtattgaaa gaaatgcaaa aacaatatga tgagttccga
     3121 caagaataat aatgaataaa gacaaagggg ttgtgacaaa agacgtgtca caacctcttg
     3181 ttccgaataa acggtgttca aaagccagtt tctcggtatt aagctaaata tatgtaaaaa
     3241 tgtggaaagc catattcaca aaatttttct tactactcga aactaagcgg ctatttcaca
     3301 aactcttggt aaacggtgtt caatcagctg accctcggta ttcgctcaca aaacgacaaa
     3361 atatgaggaa ctatttttcc gtttgtttct ctaataatca ggtcaaggtg ctgattgccc
     3421 aacctttttt tgtataatga gaaagtataa acttaatgtt tggaggagaa gatatgttag
     3481 ggaaggtttt ggaagagtta tttatccgga tctgggtcat tataaaacta accttgtatt
     3541 tctggatata tacatttgcc ggcgggatca tctttggatt aggtgcggca tggaaaacag
     3601 tcaatgaact attttatttg tacggattcg agtataaaga aatcacaata aaaagaggct
     3661 ggaatatata taaaagaaat tttttaagag gcaatctgct atttagttta tttttatctg
     3721 gtactgcttt attgagttac aatttatatt tatctgttca aatcaaaggg ctcatttttt
     3781 tagctattga ttttatttta ctttttgcct tgctctgcct atttgctact tatcaataca
     3841 gtatgatttt agatagtgaa tatacgatct ctgttcctaa tctgctaaag ctaagtttta
     3901 tttcggtttt ttccagcttt tcgtcttttc taaaaataat tattggtagc ggtataattt
     3961 taggcgtgac ttggcaattc aaaggattga tcctgtttgg tgtcattggt cttttgacgg
     4021 tttggaatgg tacgatgaca acacattggc gtgaagaatt agataaacag ttggaaagtt
     4081 atgaataagt ttcggattct attttcaaaa ggaaccttac taaatcgtct gttgcggaaa
     4141 tacgcggtta tcatgatcgg tgtaacgatg actgctaccg ttatttttag tatccatact
     4201 tgggaacaaa atcaaaaaca ggcagaaaac atgacaagtg atgccgttca aagcacaagc
     4261 agaatgctga atgataaaac aaccttgagt aggatcatca aaaaccagct tgtagggaat
     4321 tccgaaaaga tcgaaaatgt gacgacctac ttaacaaaac ccatagatca gtatctgatg
     4381 tatgtatacg aacagcaaaa cagtaccgat gaattagttt ctttcccaaa tcaaatcaaa
     4441 gatctctacg caaattatga agaactaagt gcgatatata tcgtgttgaa tcaactaccg
     4501 gagtattatg aatcttctag agaaaacaaa ggtggggaaa taaaaaaggg gacaccaaaa
     4561 ttactagacg ccttttatat caagttgcct atcacacaag gaggagctga gtcaggaagt
     4621 atttttattg gttttcaaaa gaaagaacta gatatgattt tagaaaatct aacgtcattc
     4681 aatggactct ctttatacat gatttctgga acgacaaatc gactatacac attccatgat
     4741 aataaaatag ctaaagaaac gtttgaaaga caagaaatga tcatcacaga gagtctgaag
     4801 aaaaattcac aattgccgat tgacgatctg gaaaaaaaca attttgttca acaccaagaa
     4861 ctgtctgatg attatcgtat attagctgta ctagataaaa aaagtgtaaa aatcgaaacg
     4921 ggaaaaaatc ttgccccgct gatcattggt atcattattt tagacaatat actgcttatc
     4981 tttctttata aaacattcaa acgatattca cagcaagtat ctatcgtcat gcaggccatg
     5041 gatcaaacag cagcagggaa tttagagacg cggatcgaca taacaaacac ggaatatgaa
     5101 ctgaaggaac tttcaatcgg tatcaacgaa atgttggata gcatcaatca gtttgtagaa
     5161 gacatctaca aattagaaat caaacagcaa gacgcacata tgcgggcgct tcaagcacag
     5221 atcaatccac actttttata taatacatta gaatatatcc gaatgtatgc aatcagcgaa
     5281 ggaagtgaag aattagcaga tgttgtgtat gcgttttccg ctttgcttcg aaacaatacg
     5341 aatcaagaga aaacgatcac tttaaaagaa gaactggact tttgcgaaaa atatgtctat
     5401 ttgtatcaaa tgcgttatcc taatcgagta gcctatcatt ttatgatcga tcctgatttg
     5461 gaaaagatcg aagtacctaa atttgtgatc cagccattag ttgaaaatta ttttaaacac
     5521 ggtattgatt ttactcgatt cgataatgcg ctaagtgtca aagtcttgca ggaaggcaaa
     5581 cgggtaagga tcatcatcaa agataatgga aaagggatga ctgaaaaacg gctaaaacag
     5641 attgaagaaa aactgtctca tcctaaagtg gaacttcacg gttctatcgg tctgcaaaac
     5701 gtgaatgaac gtttacgtgc cagcttcggc agcagttatt atatgtcgct tgagaataat
     5761 gagacaggtg gactgaccgt ttctattaca ttcaaggagg gatgagcgtg tatcaagtgt
     5821 tattggtaga tgatgaatac atgattttga atgggttaaa aaagataatt gattggcaaa
     5881 gtttaggctt tcaaatagta gcaacagcag agaatgccaa agaaggacta gctgtacttg
     5941 aacagcgaca gattgattta gtagtaacgg atgtgacaat gccagaaata aatggactgg
     6001 aatttattga agcggctcaa aaagaacgtc ataattttga atttatgatt ttatcaggat
     6061 accaagaatt cgattatttg aaaggaggta tgcaattagg cgccgtgaat tatttgatga
     6121 aacccgtgaa taagttcgaa ttggttgaaa gcctcaagaa aatcaaaaca cggttagatc
     6181 agcaaaatga acaaaaaaat caacaagaaa tctatcaaga actgttattc agtcaatggt
     6241 tgaatgaaga attggatgaa ataagtgaag aagaaataat aggacaaata agtgagaagc
     6301 agcataggat agtattgatt caactggcaa gaactcatga tactcttatc aatagatggt
     6361 tgcaagaacg gcaacaaatc ttttactatc aacgaaatta cggagaccgt gtattgatca
     6421 cgttgttgtt ggaggcagat gaagttgatg gcttctgttg ttttgttcaa gaaaactttc
     6481 ctgatcagga atggctgatc agtatcgggg aagagacaga ttctttggac aaaatccctg
     6541 aaacattcca acaagcgaaa gacaatctac agttgcatca attttatgga gataaagacg
     6601 agcatgtttt ttacgcagta caagcagaaa caaaagatca aaccatcgat ttttcaagtt
     6661 tcagacgcgt gctgcaaaat aaacaattgg aagtcgctca aaaaatgatc actgattttt
     6721 ttgaacagtt tcagttagca gccatgatgc cggaagatat acgatattcc agttttttac
     6781 tgtttatgga gattcaacgg gaattgattg atctggaaga tgaggaatat ttacaaggaa
     6841 tcgaaaaaat ccatcaggca aaaacggtgc aagaacttca gcagctactt ctgtcattca
     6901 tcaaaaagca tcagagacag aaaaagtaca gtgacaatgt ggaaaaagta atcgtaatcc
     6961 tgcaccagca ttatcaagaa ccacttacac tcaaagaagt gtcagaaaac ctgcatttaa
     7021 atgtcatgta tctaggacag ctgttcaaaa aagaaacgaa aaaaagtttt tcagcttatt
     7081 tgaaccattt acgtatggaa aaagcgaaac aactgctttt gcacagtaat caaaacatca
     7141 atgagatagc aagtgagatt ggctacaaca acaccacgta tttctctaaa ttattcaaga
     7201 aaatcgtcgg cagatcccct aaagagtacc gagaaaacag tggagaatca taaaaaaaaa
     7261 agccaatgta atgaaataac ttataaaaaa ttgtctagaa atctaatttt gggctgttct
     7321 tattacttga ggcaaggcag ctttttcatg acctctcgat aaacggagtt caaaagccag
     7381 tttctcggta ttaagccaaa tttatgcaaa aatgtggaaa gccattttca caaaattttt
     7441 cttaatactc gaaactaaac agctttttca cgacctctcc actaaatggt gttcaatcag
     7501 ctgaccctcg gtattagctc aaaaaatggc aaaatatgag gaactatttt gccatttgtc
     7561 tctctaatac tcaggtcaga acgctgattt cacaacctct caataaacgg tgttcaaaag
     7621 cttgcatctg cggtaataag accaaccaaa cgaaaaatat gaggatctat ttttgcttgg
     7681 ctgttcttat tacttgatgc aggacagctt tttcacaacc tcttgttaat tatagtttga
     7741 taaggaaaaa ggcaaatctt ttgcttgata tttcttaggg tgagggatga tccctaattg
     7801 gtaagagatc gtgccgcctt tcagcaaatc ttgatgggta aaatataatt tcgtatattc
     7861 tctgtccatc cgtttgattt tatggataaa ttgttgctgc ggccgattag gcgttgcttc
     7921 aatcgtcaat tcctttccat ttgacaaaag caaaacagcc ttgtcaatta atggcatacc
     7981 gataacatat tcaccggttc caggcgtgac aggataaaat cccagactat tgaagatata
     8041 ccaagcggcc atacttccat tgtcctcatc tccagggtaa cccattggag aatcgtcgaa
     8101 ggtctgagtc atcaactgtt taagcagtgg ctgtgccatt tcaggttgtc ctatataact
     8161 gaacaagtaa ggatagtgaa aacttggctg gtttgaaata gctaattgtc caaattctat
     8221 cgcggccatc tcactcattt cgtggatctc aaaaccatat cctcctgggt caaacgttgg
     8281 gggctgattg cacagctcaa tgagtttttc tttatatctc tcactgccac catattttcc
     8341 gatcagtcct gaaaaatcgt gataaacagc aaagctgctt tgccaagcac ttccttctgc
     8401 ataatcttgt ccccaacgat tagctgaaaa tggttctctg aacttgccat ctttatcttt
     8461 tgaacgcata aatcctgact catagtcaaa gatattttga tagttcaatg attgctgctg
     8521 atatttcttc gtcatttcct cttcttctag taccttggca acttggctaa tacaaaaatc
     8581 gctataagca tagtctaatg tgtgattgac tgattcgtgg tagtgattag gaacatagcc
     8641 atatgtcaag taatcttctg ttccttggcg tccataattt ggatgtttgc tttgaaccgt
     8701 agcacctttt tccattgccg ttagaaattc aggcatcaag tctcgtcgga tatcttttac
     8761 agcagcatct gcaatgaccg catcgatcaa tgtcccaggc ataagtccac gttcatcagg
     8821 agacagccat tttggcaaat agccactttc tctatagctg ttcaaaaaac cttccagcat
     8881 ttcttcgtat ttttctacag caatcaaaga ataaagagga taaaccgttt tatacgtatc
     8941 ccaaaaccca ttatttgtat agagaacacc aggttttata gatcgactag tcgtatcata
     9001 gtggattttt tgcccactag gatcaatttc ataaaatgtt tgtggaaata aaaacacccg
     9061 atataaatta tgataaaacg tccgcaattg ttgttgatca tggtgtgtga gctgtatacg
     9121 atcaaaatag gactgccatt gttcttgact gtgagcaagg taagtctctt tgctttggtt
     9181 ttgttctagt tccaggttat aagctgcttg ttccgagctg ataaaagatg tcccaaatcg
     9241 gatagtttgt ttttttgtct gttcaaaata caacgggatc gagtcgctat ttttgttgga
     9301 aacagctaac tcatcaattg ttaaaggata ttcaaatctc aatataaaat aaaaagaaaa
     9361 atcaggatct tctgaaccag caaaatgtgt gatttttcct tccactgtgt aaggatctat
     9421 aacaaagagc tgatggcgtc ccggaaagga taaaagtaaa ccgctgtcat ttttgctgta
     9481 atcaatagat aagattccgc catacatgct aggtatcaat gtagaacaga tgccataacg
     9541 taattgacag atcgacagat gagtcgggca aaatatactt tcttctgggc ggtaagaact
     9601 ttgagcatgg aaaagggtgt tctcctgtag ttttccattg atcggcgtaa acagcatatg
     9661 actgaaatca cccatccaag gacttggttg atgggtaaga cggtagcctt gaaaaacgcg
     9721 gtcatcagga tgaaaccacc agctgccgtt ttgatccgta gtttgcggtg caaaataatt
     9781 catcccaaaa ggaacgccag tataaggctg gcagttccca ttagagaaat ttggctgatt
     9841 cgctgttgca tgtctagtat ctatttgacc gatattcatt ttatttctcc tttgttgatt
     9901 gtcttttgat gaatgaaact ggaaatttac tatcggatgg tcgatctttt gtctctaacc
     9961 aagtgaccaa agcatctccc gcaagcttac ctaactgttc aaaatcttgt gcgatggttg
    10021 tcagtggcgg gtcaacaaga gctgctgctt ggatatcatc aaatccgata attgaaaaat
    10081 cttcagggat atgataacca tgctgtctca agagattcat ggtctggata gcgacaacat
    10141 cgttttcaca aacaaaagca gttacttcat acttagtgat ataagaaagc aattcatcta
    10201 atgtcgcgct tttgtcatcc agtgaagtgt ggaaagtcaa accagctttg tccaatgctt
    10261 caaggtaacc aaggtaacgc tgtcgaacgg attgtggatg agtctgcgta ccaaacaaat
    10321 aagcgatttt tgaatgtccc tgttcgatca aataagaggc agcaagcgca ccgccttgga
    10381 aattatcgga aagaacggta ggaaaaggta actcatagat ttttttatct aatatgacga
    10441 cagggaattc tttcaatgaa agctcaaaaa gtaagtcaag atgttgttct gtatcaagag
    10501 cataataaat caatccgtca aattcattga ttagctcttt tgctgtttta ttttgtagaa
    10561 agtcaagcgt cgtcatcatg acatcaatct gtttatcttg catcacaggg ttcaatccct
    10621 tgctaaaatc accaacagac aaatcagcga catatggaag aagaaacaga atccgtcgtg
    10681 tttttgtagg agaagcaaga atctgttccg gagaagcgga tttaacgaaa ctgcctttcc
    10741 cgcgaacgcg ataaataagt cctaattgct ctaattcagt caatgcacgt ttggaagtga
    10801 ttctgcttac tttataggta cgtgaaagtt ctttttcagt tggtagttgg ctgtctacag
    10861 gtaattcacc agttaaaata gccgtttgca aatcattaaa tattgtctgg tacaatggtt
    10921 gagtcatata aacacctctt aatgatatat catattcaaa taataccata atggatgaaa
    10981 aagtaaataa aaagatattt tttgaaagcg tagacataat tggctgtatg aagtataatc
    11041 tttaaagata tatcaaatag aaagaaggtt ttattagtgg tttataaaga tataccaaaa
    11101 tcggtgcaga aatttatgga agatatcaca caaaaatgtg gggatatcca tgcggactgg
    11161 gcaaagaatt ttacagcagc atttgccaat actctgttga caacagtcaa aaagcaaaat
    11221 gacggaacca cctttttatt gacgggagac attccagcga tgtggttaag agactctact
    11281 gcacaagttc gtccttattt agtgattgca aaagaagatg aggaattagc tgacatgatc
    11341 agcgggttag tcaaaaagca atttttttat atcaatatcg atccatatgc gaatgccttc
    11401 aacgaagaag ctaacggtgc tggccaccaa acagatcata caaaaatgaa cgattggatc
    11461 tgggaaagaa aatatgaaat tgattcttta tgctacccaa tacagttggc ctatcttctt
    11521 tacaaaaata caggaaaaac tgatcaattc aatcaatctt ttattgaagg tatcaaaaaa
    11581 atcttggacg tgttcaaaac agagcaagat catgaacact ctccttatac atttgtacga
    11641 gacacgacaa gaaaagaaga tacgctgatc aatgacgggc gaggtgcaaa aacagctttt
    11701 acaggaatga catggtctgg tttccgtcct agcgatgatg cttgccgtta tggatatctg
    11761 gtaccatcca atatgtttgc ggtggtcgtg ttaggttatg tggaagaaat ttttcaaacg
    11821 atactcgatg ataaagaaat tgtacagcaa acacagaaat tgaagaaaga gatccaagag
    11881 gggattcaga atcacggacg aacggttaat caaaaagggc aaacgattta tgcatatgaa
    11941 gtagatggaa tgggaaacgc cacagtcatg gatgacagta atgtgcccaa tctgatcgcc
    12001 gcaccttact tgggatattg ttctgaacaa gaggaagatt atctgcaaac aagaagaaca
    12061 ttgttgagta aagaaaatcc atatttctat gaaggaaagt acgcaaaagg aattggatcc
    12121 tcccatacgc cagaaaaata cgtttggccg attgcattag ctatggaagg aatgacaacg
    12181 tcagacaaat ctgaaaaaga gcggatattg aatttacttg tagcaactga cgcaggaaca
    12241 caccttatgc acgaaggatt cgatgtgaac aatcctgaaa attatacgag agaatggttt
    12301 tcttgggcaa atatgatgtt ttgcgaatta gtcatggatt actttgatat tagagtagaa
    12361 aagtaggagg tatcgtaaat gaaaaagaaa gtatatatca tttctcatag ccactgggat
    12421 cgtgaatggt acatggctta cgaacagcat cacatgcgac tgattgaatt gatagacgat
    12481 ctactagagc tatttgaagt tgatccgtcc ttcaacagtt ttcatttgga tgggcaaacg
    12541 attattttag atgactatct tcaagtaagg ccagaaaaaa gacaggcaat ccaacaagca
    12601 atcaatgaag gaaaattgag aattggacca ttttatatct tgcaagatga ttttcttatc
    12661 agctcggaat cgaacgtgag aaatatgctg attggcatgg aagaaagccg taaatgggga
    12721 acccctgtca tgttaggcta ttttcccgat acatttggaa atatgggaca gacgcctcaa
    12781 ttaatgaaac aagctggtat ttcagcagca gcgtttggcc gtggtgtaaa accaattggc
    12841 tttgataatc aagttttgga agcagaaaac tattcttccc aatactcaga gatgtggtgg
    12901 aaaggccctg atcaaacagc aatctttggt ctgctatttg ccaattggta tagcaacggg
    12961 aatgagattc cagtagaaaa agaagcagct cttgcctttt ggaagcaaaa attagcggat
    13021 gcagaacaat atgcctctac gaaccactta ttgatgatga atggtgttga tcatcaaccg
    13081 gtacaaaaag atatatcaaa agcaatccat ctcgcaaatg aactgtttcc agattacgag
    13141 tttattcatt ctaattttac tgactatctg gaagcagttc aaaaagatgt gccagaagac
    13201 ttaggctcag tagaaggaga attgacaagt caagaaacgg atggctggta tactttagcc
    13261 aatacagcat ctgctcgggt ttacttaaaa caatggaata ccaaggtcca gcgacagcta
    13321 gaaaatatta cagaaccact tgcgacgatg gcttatgaag ttagtggaaa ctatccccat
    13381 gatcaattag attatgcttg gaagacatta atgcaaaatc atcctcacga cagtatttgc
    13441 ggttgttcag tcgattctgt ccatcgggaa atgatacctc gttttgaaaa agcagatgaa
    13501 gttggaaagt atcttgcaca agattcctta gaacagctga ccgcagcaat cgatacgacc
    13561 ggattcccaa aagacagctt tccatttgtc attgtaaata ctgcaggaat ggataaaact
    13621 ggtgaagcag aaataaccat cgaattagaa agaaaaagat tcgctgaagg aatacctgaa
    13681 caactatatc aagagttaga aaatttgcct aaacgtaagt atcatgtaga aacaaaaagt
    13741 ggggccacta taccagctat tttatctgaa gaaactgtcc aatttggtta tgatttgccg
    13801 aaagaccgtt tccgtgtgcc atatatggca agaatgatca aagtgacttt accattagaa
    13861 aacatgccag cattttcttg ggaaacattc gcgcttgtag aaggggaagc gaaagcagaa
    13921 gaaaaggaaa caatgattca tcagagtgga cgaatcatcg aaaacggccc tctacatttg
    13981 acgattgaaa aaaatggtac cattacaatg gaagatcgca aaaacaaacg aaagttgaat
    14041 aatctgcata tttttgaaga tatcggcgat ataggaaatg agtatatctt taaacaacct
    14101 ttctgtgatc agccaatcct atccagtaac aaagaaaact ctgaagtaaa agtattagta
    14161 gatacaccgg aaatagcaaa aataagtatt ctacaggaaa tggaaatccc tgtttctgca
    14221 gacgagcgtt tagaaaaaga acagcagatg gttgtggaat ttcgttatcg aaaagcagaa
    14281 cgatccaaag aaaaacgaat ccttcaaata aaaacaatca tgacaatcag aaaagatagt
    14341 aaaaaaatcg actttgaaac gactctcgac aatcagatga aagatcatcg cttacgtgtc
    14401 ttgtttccta caaagttaca tgtggaacat cacgaagcag atagtatttt tgaagtggtg
    14461 aagcgcccaa accatgtgtc taaaagttgg gaaaacccca cgaatccgca acatcagcaa
    14521 gcatttgtca atattcatga tgaagagtac ggtgtaacag tcggaaactt tggtttgaat
    14581 gaatatgaag taacagaaga cggacaaatc gcagtgacgc tacttcgcag tgtgggagaa
    14641 ctaggcgatt ggggatattt tccaacacca gaagcacagt gtctaggtga gcatcggttc
    14701 aattacagca ttgaactaca tggaccagaa gaaaaattct ctacttattt gcatgcatac
    14761 gcagcacaga ttcctttttc cactcaacaa atcaaacatc atgaaggaac attgatttca
    14821 aaacaacaat atttaacgat aaaaagtgaa acgtttgcaa ttacagcttt gaaacgcagc
    14881 aagtttagtg ataaagtagt agtaagaggt ttcaatatgt ctagtcattt agaaaaattg
    14941 gaaataacta aagacaatgg aaaaactgtc atattgaatc tgcttgaaga accaacgaag
    15001 caagcggttg tcccaataat ccaaccttat gagattcgga caatcggatt cgaggaggaa
    15061 aacgaatgta tggcggaata gaagcaggcg gaacaaaatt tgtgtgtgcg gtttcagatg
    15121 gtggagaaat tttagaaaaa ttaagtatcc ctaccacaac accagaagaa acattggatc
    15181 aggtatttga attttttgat cgttatgaat tgaagggaat cgggattggc tcattcggcc
    15241 cgattggtat cgacaaaaca aaagataatt acggatacgt tttggcaact cccaaaaaag
    15301 ggtgggcaca attcgatttt cttggcacaa tcaaggaacg ctacaatatt cctgctgctt
    15361 ggacaacgga tgtcaatgct gctgcatatg gggaattgaa gcaaggagca gcacaaggaa
    15421 aaaatagttg tatttacctt accgtgggaa caggaatcgg tgcaggtgtc gtgatcaatg
    15481 aagaaatttt ttcagggatc gcacatcctg aaatgggaca tatttgggtg aaacgccatc
    15541 cagatgacca ttatgaaggt acttgtcctt atcataaaga ttgtttagaa ggattagcag
    15601 caggaccgtc tattgaggca cgcacaggga tcaaagggca agatctgccg caagatcatc
    15661 ctgtttgggc tattcaggct tattatattg ctcaagcact gatcaactat acgttgacgt
    15721 tagcacctga aaagattatt ttaggcggtg gggtaatgaa tcaggatcat ctccttcaaa
    15781 aaatccgtca gcaatttgtt gaattgatgg gtggttatat ggaaacacct caagtaagtg
    15841 aatatatcgt tcgttgggga ctgccgaatg aaagtgggat tatcggtagt ttgctgttag
    15901 cagaacacga acatcaaaag taagcagaca aattacacaa aaagaacaga gtcttatcat
    15961 tatctgctga taagactctg ttctttttta tttctattcc cataatccag gtaaagcttt
    16021 accgactatt ttttcttgag taaatggatg gatcatgtgc agttctaatg catggagcat
    16081 cagtcgttca gctgttctat tttggtagag agggtctcca acgatcggat gtcccttatg
    16141 agctaaatga actctgatct ggtgtgtacg tccggtttcc aaaacacaat agacttgtgt
    16201 ttgttcagaa agtactttgt tgacagtgac atgtgtcaag gcgctctgac catttttatc
    16261 atctacgacc ctttttctcc gatcatggcg atctcgtcca attttattgg tgatggtcat
    16321 atctttggca atttctcccc atacgatggc ttgatatctc cgatagatca ttttttgttc
    16381 caacattctt ccaagtatcg gcaagacaaa tggatttttt gcaaataaaa cggcaccgct
    16441 tgtttctttg tccaagcggt ggacaacgta aggtcgttgc tgtttagtgt cgagataagc
    16501 agctaaatga ttgagtaagg tactgttttc tgtcggttca tttggatgag tcttcattcc
    16561 tgcaggctta tccactataa tcaaatgctc atcttcatat aaaacacgga tgtgcttcgc
    16621 atctcctaat tgaacttctt gataattata atctgtttct tcgaataaca atgtgatctg
    16681 gtcattgccc tttacttcat gatggaacaa agcaggttgt tgattgatcc aaacgttttt
    16741 acgtatacgc aaaaagtgtc gaacctttct aggaactaac cattcctttt caagcaagtc
    16801 gcgaattgtt gtttcaggat ggttcatagg taaagtgatc gtgattttca caagtgtact
    16861 cctttcagtg caattgcaga ctaattgtac catttttaaa acatatttaa gaaaaaactt
    16921 acatttttct gttcattctt atgttactct acttgcacta acgtaaaaaa acatattgaa
    16981 ctacaactta agcaggaaga aaacactctt tcactatggt aaaataagac gattgaatca
    17041 aatagacagg agaagaagca aatggatttt caaagcattt tagaaaagat aaaagctgct
    17101 ttgatcagtt tttggcgttg gatcagacca tatctcggac aattccatcg atggcgaaag
    17161 cgcatctgga aaaaatatca tgtgaacaaa ttgattttgc tgattggttt gatctgtgtc
    17221 ttagtgacaa gtatctacct ctttatttta gcaaaacaag caaatgtcga aacgttaaaa
    17281 tcaggattaa gccaatcgac agtcatttat gataagaaaa acgaagaagc tggcacactg
    17341 tacgcccaaa aaggaacata tgtagaatta aacgcgattt ctccctatat ccaagatgca
    17401 gtaatctcga cagaagatag gaatttttac gagcatcacg ggtttgatat caaagggatt
    17461 gcccgtgcag cagtccgaat ggtcttgtct ggcggaacat cagggggcgg aggaagtacg
    17521 atcactcagc agcttgccaa aaatgcgtat ctgacattag accaaacgtt tgatcgaaaa
    17581 gcgaaggaat tatttttggc aatcgagatc gaaaagaagt acagcaaaga agaaatcttg
    17641 accatgtatc ttaacaatgc ctattttggc aacggggtat ggggtgtcca agacgcttcc
    17701 agaaagtatt ttggagtaga tgcaacgaat gttacgctgt ctgaggctgc tactttggca
    17761 ggaatgctga aaggtcctgg tatttataat ccgatcgatc acccaaaaaa tgcgaatgat
    17821 cggaaaaaca cagtactaag tgtaatggaa gaaaacggaa aaatcacaaa agaacaagaa
    17881 caagcagaaa gccagacaga tatcagcgcg tatcttaatg acacatacga taattcagat
    17941 tctggttatc gttatcctta ttattttgat gcagtgatcg atgaagcagt taacgagtat
    18001 ggtcttgatg aagaagatgt catgaataaa ggctataaaa tctatacagc tttagatcag
    18061 gattatcaaa agcaattaga agctacttat caaaacagtg cattattccc agcaaatgct
    18121 tcagatggtg ccatggtcca atctgcttca gtagctttag atccgaatac aggtggtgta
    18181 caagcactag taggacgaag aggagatcat gtctttagag gattcagctt tgctacacag
    18241 atgcgtcgtt caccaggatc aacgatcaaa ccattaagcg tatatacacc agcactggaa
    18301 gctggataca agccttccag tatcttgaaa gacgaaccgc aaagttatta cgatgcgcat
    18361 aattttgacg ggacatacca aggagaagta ccgatgtatc aagctgttgc acaaagtttg
    18421 aatttgcctg ctgtatggct tttgcatgag atcggtttac aaaaaggata tgataaagca
    18481 gaagaattcg gcctgccttt agcaaaatct gataagtatt atggcttagc ccttggtgga
    18541 ctggaaaaag gagtatctcc attgatcatg gcgggtgctt acagtgcatt tgccaatgat
    18601 ggtcagatgt atacgccgca tcttatcacg aaaatcgttg attcgactgg agcggtgatc
    18661 gtcgataaca caaacaaaaa accaaaacag gtcatatcaa aggaaacagc cgatgaaatg
    18721 accagcatgc ttcttggtac attttcaaat ggaacagcgg ctgctgcgaa tcctgcaggt
    18781 tatacgatag cagggaaaac aggaaccaca gaaactaatt tcgatgccac aaaagcaaat
    18841 gaccaatgga tgatcggtta cacgccagac gtagtgattt cgacatggat gggttacgaa
    18901 gaatccagca agctgcacta tttggaaggg acaagtggaa atgttgtcgg gaaagtcttc
    18961 aaatcagcgg cagaaggcat ccttccgtat acttcaaaaa caggatttag tgtagcagat
    19021 gcctatgcca caggaggaca agtggtagct gcagatcaag ttggaaacac aggaaattct
    19081 aatggagagt ctggaaattg gcaagataac ttgaatcaat atggtgaaca agcaaaagaa
    19141 gggctgaaaa acttcggcga tatggtgaaa gaaggcgttc agggaattgg tgaagcggct
    19201 aaagacctct ggcggaaata tcaaggagag tagccccttt gaaaacgaat aaccccatgt
    19261 tacaatagag agtaactact aaaagaaaag agggcataac atgtcaaaca tctacgatag
    19321 cgcgaatcaa atcgaacgtg agatccgtga attaccagaa ttcaaagcgt tgaaagaagc
    19381 gtacgagaaa gtacaagcaa acgaagaagc acacaaactg ttcaaagact tccaagcgat
    19441 gcaaatcgaa ttacaagaaa aacaaatgag tggacaagag ttcagcgacg aagatgcaat
    19501 gaaagcacaa gaaatggctg tgaaaatcca atcagaagaa gtaatcaatg acttgatgca
    19561 aaaagagcaa ggcttcagta caatcatcaa tgacttgaac cgtatcatca tgacaccagt
    19621 tcgcgacctt tacagcgaat aaaactattt tatgaaacaa cagagggtgt gaaagagacg
    19681 ttcggccttg agcgatgaca aaattgcttc ttattgccga taggctgtct cttgaacacc
    19741 atttaccaag aggtcgtgag cctaccgttt aactctgagt tacaaggaac aatttcaaaa
    19801 aacagcttct catgtttgat gactattgtg acttgtgacc gaggagttgg caggagaaca
    19861 ccgtttattc agaaatagga gctacgacaa aagtcttgtc atagctccta ttttttgtca
    19921 ttcatttttc aagcggtaga aatagccttt ttgagctaac agtttttcgt aagtacctat
    19981 ttcaacgatt tttccttcat cgatcacaac gattttatct gcctctttga tcgttgaaag
    20041 ccgatgagcc acaataaaag tagtgggtgt ttctgtcagg taattcaggg cttgctggat
    20101 ttttttctct gactggttat ctaaagctga ggttgcttca tctagcaaaa tgatttttgg
    20161 ctgacgtatc aacgctcgtg caatggagat acattgcttt tggccaccag acagcttgtt
    20221 gccatgttcg cctactaagg tatccagacc atcaggaagc tggtcaatca gtgaagaaag
    20281 ttgcgcagct tcgatgactt catctaaacg ttcttttgat acgtttttca agccataagt
    20341 gatgttctct ttgatcgaag cggagaacaa caaagtggtt tgaggaacaa cggctaaata
    20401 atttcgcaca cttcgcatat ccagttcatc caaaggctga tcatctagaa aaatttttcc
    20461 tgaagtcggc tggataaatc caatcaataa gttaaggagt gtagattttc cagagccaga
    20521 tggcccaaca aaagcaattg tttctccagc tttcacctct agagaaaaat gatcgataat
    20581 cggtttgagt gagtccggat aaagaaaaga aacatcctca aaacgaaaat ttccatccaa
    20641 atgttggatt tttttcttac cgtgataagt ttctacatcg ccagcaatca acagttcgcc
    20701 aatagaagtg atagattcca tgccttttga aatcgtagga atcagcgtga tcattccaga
    20761 aacggaattg acgatcgtcg tgaaatacgt ctgatacatc acgacatcgc cgggttggat
    20821 gcgcccttgt aaagctaata tcccagtgaa actcaaacaa atcagctgaa atatctgaaa
    20881 actagcccag ctgactgatc cgaaaacaga ttgcaggata tctaagtgga atcctttttc
    20941 atagatttga gtaaaatgct tatttaagcg agttgtttcg tgtttttcta acccatgagc
    21001 tcgagcaatc ggtgctaatt cgatcacttc gatcactttt gcagaagtct cttccatttc
    21061 ttgcctgaag tctgagttgg actgtctgat ccttttacgg aaaaagagag taacgaatgc
    21121 ggcgagagga acagtcaata agaaaaacat gaaaacaaca ggacttttat aaagcgtgat
    21181 acctaaagct acgaataaat tgacagcgat atttaatccg ctgacaaata cttgagagga
    21241 caacgtttgg atagcttcta catcacggat gatctttgac tggattcgtc cagattgcaa
    21301 ttctttttga taaggaatag atagttcttg gattttcttg ataagggtcg ctcttagtcc
    21361 agcttctact tgacggatcg aagtgctatg gtattttaca tgaaaataat tcgtcaatat
    21421 attttgacca atcagacaag ccatcaaaaa agcgttgaaa taaatggcct gcaactgaga
    21481 agaatctttc gatgaagctg cattgattac attggcaata gcgatcggca ttaaccaaga
    21541 tggaagatgt ttgataataa aaaagagtcc tgacatggca aaacgccaat aatttccctg
    21601 ataaagatgc agcaatgtct gaaaagcatt tgcatgatat ttttgataac ttttctgtat
    21661 tcgttcctcc ataatcttct ccttaacaat cttggtaaat aaactgcaag tgttctattg
    21721 cttcaggaac ataaatctca ggagtagctt caagagtggc gtacattaga ggacgctcat
    21781 atttgatata atgcagtacc gggcggaaat ctaaacagcc cttgccaaca ggtaccatgc
    21841 ggatctttcc attttccatg atatagtctt tgagatgaag cgctgtaata taaccatgta
    21901 aattgtccaa ggcacctcgg atcacttttt cctgatcagc atgattttct ttatgcatca
    21961 aattcgcaca atctaaaatg atttttaaat ttggtgaagc tacttcatcg attaaacgtt
    22021 tagctaactg atagttatag attggatgat tgatccctgc ttcaacagca acagttacgc
    22081 caaaattttc tgcatgagcg actaattcaa tgatagaatt tctggcgatc tgataagctt
    22141 cttcagtaaa attttctttt gtgtaaccga cagagacact accggtttcc gtagcaatca
    22201 tcttggcttg ataggcagag cacagagcaa tttgctgttt gaaagttgcc aatgcttgtg
    22261 cacgaacttc ttgatttttg ctggataggt tgatatagca tcctaaaatg gaaagttcga
    22321 tattgttttt ttggaagtat tcaccaaaat aggcagcact cccaagtgtc atgtcagtta
    22381 atttaagttg ttcaggaaat gctttttgtg gtgcaaattg gatatgggac aagtgaagct
    22441 gtgatacttt ttgaacgatt tcttcacgat ttcgaacatc taaatcgtgg gcacggatgc
    22501 ctaaatttaa tggaaacatc tcaaactcct ttttgtaaat aattagcaag aggcagacgg
    22561 gattctttta tcaattcaac aattattcgg gcaactttat cagcgccttc tggactaaag
    22621 tgggtattgt cttttagtcc ttctgggtaa tttttacaag tatcaggcat aagatgcagg
    22681 tagaattttt ttgtctcttc ttttgagaag gtctggaaca attcttgtga tcttgagaac
    22741 acatctaaaa gaggaatatg gtgtttctca gcaaatgcac gcatcgcttt tggatagtct
    22801 ccaagtatat ctggattcaa tgttccgttt tctaagtaat ctcgtcgcgt cacagatgtc
    22861 agtaagacca tttggacgtt cgcttttttt gcgcattcaa aaaatatctg cagatttttt
    22921 aaatagctac cgaagggaag cgtacctctt tcttcttgga ttttctggtc gttatgtcca
    22981 aattgtacaa ataagaaatc attcggctga aactgtgaag ctagacgggc taaccttcct
    23041 tcctggataa atgatttggt gctgcgtcca ttctttgctt ggttattgat ctggatctcg
    23101 ggtgaaaaat aagcagagat tttttctccc caacctgtct cgggacgctt gttttcatct
    23161 ttttctgccg cagtagaatc accggcaata tggatagtag gcatgttatc tcttctttca
    23221 taaaggttta taggcaatga agcagaacag caagagaaga agacggagca a
//
LOCUS       DAZKCW010000041        22024 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000041 DAZKCW010000000
VERSION     DAZKCW010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.041"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(59..1369)
                     /locus_tag="ACG84Z_001864"
     CDS             complement(59..1369)
                     /locus_tag="ACG84Z_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFP9162677.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1381..2799)
                     /locus_tag="ACG84Z_001865"
     CDS             complement(1381..2799)
                     /locus_tag="ACG84Z_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9162678.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3039..4607)
                     /locus_tag="ACG84Z_001866"
     CDS             complement(3039..4607)
                     /locus_tag="ACG84Z_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFP9162679.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4611..4892)
                     /locus_tag="ACG84Z_001867"
     CDS             complement(4611..4892)
                     /locus_tag="ACG84Z_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFP9162680.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4889..5812)
                     /locus_tag="ACG84Z_001868"
     CDS             complement(4889..5812)
                     /locus_tag="ACG84Z_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFP9162681.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5809..6687)
                     /locus_tag="ACG84Z_001869"
     CDS             complement(5809..6687)
                     /locus_tag="ACG84Z_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFP9162682.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6674..8011)
                     /locus_tag="ACG84Z_001870"
     CDS             complement(6674..8011)
                     /locus_tag="ACG84Z_001870"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFP9162683.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8014..9117)
                     /locus_tag="ACG84Z_001871"
     CDS             complement(8014..9117)
                     /locus_tag="ACG84Z_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFP9162684.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9191..10699)
                     /locus_tag="ACG84Z_001872"
     CDS             complement(9191..10699)
                     /locus_tag="ACG84Z_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFP9162685.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10665..11357)
                     /locus_tag="ACG84Z_001873"
     CDS             complement(10665..11357)
                     /locus_tag="ACG84Z_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFP9162686.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11379..12353)
                     /locus_tag="ACG84Z_001874"
     CDS             complement(11379..12353)
                     /locus_tag="ACG84Z_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162687.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12653..13525
                     /locus_tag="ACG84Z_001875"
     CDS             12653..13525
                     /locus_tag="ACG84Z_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162688.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14107..16305)
                     /locus_tag="ACG84Z_001876"
     CDS             complement(14107..16305)
                     /locus_tag="ACG84Z_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162689.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16537..17529
                     /locus_tag="ACG84Z_001877"
     CDS             16537..17529
                     /locus_tag="ACG84Z_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9162690.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17589..19010
                     /locus_tag="ACG84Z_001878"
     CDS             17589..19010
                     /locus_tag="ACG84Z_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFP9162691.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19003..20502
                     /locus_tag="ACG84Z_001879"
     CDS             19003..20502
                     /locus_tag="ACG84Z_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFP9162692.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20541..21935
                     /gene="uxaC"
                     /locus_tag="ACG84Z_001880"
     CDS             20541..21935
                     /gene="uxaC"
                     /locus_tag="ACG84Z_001880"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFP9162693.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6668 a         4494 c         3823 g         7039 t
ORIGIN      
        1 cattaaaaaa aataaaggtc aagctaaaat attatttaag cttgacctta ttataatttc
       61 aacgattgtc aaaagtattg tttgcagctg tgttgccagt ttctatagat aaatcacagc
      121 ttttgaaaca taagttttgt actgcttcga ttcgcccgaa ttcttttgca gttatttggc
      181 aatgagaaaa gcagacatct tctataggct tttcaggaaa tgctactaaa tcaaaagctc
      241 gggaaggaag tgagtaacct ggagaaaggc atgcctgtac gtttttgatg tgtatgtctt
      301 tgactttcgt catttgcttt gattcaggta tttcttcagc cactgcttgc caactttctg
      361 gcatttgagc aaggtcattg ctattttttc tattgtattc attatgccag tccattatcc
      421 aagaaaaagg aaattgtaca tcaatcatat tcagattttc taccctgata ttttcgatca
      481 ctccccctct ttcttttgaa gatttcattc gaataccaca gtctgactga aaaaaattga
      541 tatcgtgaat atatacgtca ctaactccag cactaacttc gctaccaata gttacaccgt
      601 atcctgaacg gattttacat ctagcaacct cgattcttga tgattttcga ttgactcttg
      661 caccattgcc atctctgcca gacttaatag caatacaatc atcaccacag gccaaatcac
      721 attcatagac acgcacattt gttgaagaat caatatcaat cccatctgta cttggtccat
      781 cattgttgcg gatgattact ttttctacta atacatcgtt agaataagtg atttgcaagt
      841 tccaaaaacc tgatttctga aaaatcaaat cacgaacaac aacatgttct gcatgataca
      901 gtaaacaagc gcgtggacgt ttaatagcat aatccgcaat ccaacgaagt cccttttgat
      961 cgtattcagc tcttgtcccg cttttttgat cttttcccca atacagctcc caccaatggt
     1021 ctccttgacc gtcgattatt ccttttcctt ctataagaat atctttcgcc gagagaacat
     1081 tcaaaatcgc tgctggccat ttcatttcta cgccggctac tcgtgtatcg atttctggaa
     1141 atgcttcgat atctgttctc cccttgagga ctgcaccttc ttcaaagata agatgactct
     1201 tatcttttaa aaaaagggct ccgactaaat aaatgccttt tggaataaat acaggtaagt
     1261 gttctttcgc accttgatcg attgcttttt gcagtattat tgtatcatct tgttgagtgt
     1321 cgtttgtttt aaagttcaaa gcattgataa tccctttttt tgtccgcaat acgtttctcc
     1381 ctatctttca ttgatttttt tcaattcttc accaataaat acagtttttg aacgattcag
     1441 tgggtaacct actagcaaaa tgattgcgga tacaaataag cagaatgctg gtaacaagtt
     1501 tgccatcgta taaatccttt cttgtactaa aactgattgg atggctccac ctgttgtaga
     1561 cgattggtaa ccaatgagtg ccagcataaa tccgcctacc gctcctgcac atgcttgtcc
     1621 tacttttctc gcaaaagaat ttactccata tactgttcca tcttctctta agcctgtctt
     1681 atattgatga taatcaatca cgtcagtaat gaatgcccag accatcaaat tgaataaacc
     1741 agatcctaaa gtagcgataa ataaaagaat cagatatacc catgcatttg ttatatgaag
     1801 gaaatacatc agcaagtaca tacatgaaga agcaagtaac gcaaatacgc ttgcttcctt
     1861 tttaccaaat aattttgtca gctttgtagc aaatggtgct aaaactacta ctgttccgta
     1921 agtaaataaa agagcaacag acattgcttg tttattatgg aagtaatcat tgaataaata
     1981 agtcatattc gtcccagcta aaatctgatt gatcacaatg aaaatgtcaa caatgactaa
     2041 aataatcagt gctcgattag ctaacaaacc ttttaccaac tgagaagcag atactttttc
     2101 gtttttgaca actcttactc tttcagtagt caatttacaa gttaacatat atgcgacaaa
     2161 tgctattgca gcacatccga ttgaaatcca aaagaaatga ttccctgaaa cgacttgttg
     2221 tccactcttg ttatgggtat acattaaaat cggaatgaag aatcctgtag ttgatccgcc
     2281 aatcgcagaa ccaatgcttc ggaacgtgga caacgaggtg cggtcattag gatttgagct
     2341 aattgctgct gccattgctc catacgggat attgattgtt gagagaaaaa tcccataaac
     2401 aatgtatgaa acaaaaatat aagcaatctt caccgtcatt ggaagatgtt ggacgaatgg
     2461 caaaaacaaa atgacagtca ctaagcaaaa tggatacttc atttttctga tccaaggaat
     2521 aaatcggcca gtttctgtta actctgagac atcacataat cttccaacca tcacatcagc
     2581 aaacgcatcc aaaattctcg aaatcaagaa taacgtacct acgattgccc ctgaaacgcc
     2641 aagaacattc gtataataaa tcatcaagaa actattgact aaacctaaaa taaaacagtt
     2701 acctagatca ccgaacatgt agcctatctt atcggaaatc ccaaattcct ttttttcttt
     2761 ttttactgta tttgctgtaa cagcattttg tgaaagcatt tgaattcctc ctacctcttc
     2821 tagtaaacgt tttcaaaatt ataactcttt ttttcttgtt tttatattca caatgttggc
     2881 tttttattgc attatcttga cagataaaaa acaaaaaata atctaaaaac attgatgcat
     2941 aagattgata acttttttta cataacaata tatacaaaca aaaaaattca ctaactagtg
     3001 aaaataagtt agtgaacctc atttattaaa gaattaaatt acagatgatc ttttccatca
     3061 tacttgaaaa actcaaaatc agcataactt cctctttttt tatttagatc atgcactgct
     3121 atcccgataa aatttccagt aaaccctcct gagagtatac acatgttttt ttgcggacct
     3181 actttcttcc attcttcagt tgatacgtct ttcaaatgaa actgtgctgt ctctttcttt
     3241 acagtgactt tcaaaaaagt cttcttttct gtgagtggaa tcgtccaatc ttctatttgt
     3301 gctactccgt tttctgattc tatcatacgt aggcattttc ccttgtcctc attccaagta
     3361 acataacaat aaatataatt ggattcattt aagtacagta ccagtccagc catctgatta
     3421 aaattattag gcatgtattc aaatgctgtc tccgcatcaa aagtaaaatc cgtttgccga
     3481 atagctaaca aatgatgttc gaaggtagat tgaagagatt caccggaaat cagacgtaaa
     3541 aaacctggtc tacattttgt atcacaccaa tcagcatttg gcaaaatgcg tctggcattc
     3601 cagttcttct ttagctctcc ttcaaatgta tccataaact gatgatcttt ttcttgttgt
     3661 acctcttcat ttgtctcaat cattatttct tccatcggag ttgtctggct atctttaagt
     3721 cttaaccaat cgtcggacgt ccaatacact tcttgaatag cggtttctct tcccaaaata
     3781 gccgcaccgt ttaatggtct ggtacaaaga tatgtcatgt accatcttcc tgacggggtt
     3841 tgtactaagc tcccatgtcc tgtacattgc aatgtagaag caggtttgtc actagctgtc
     3901 agcataggaa aaccaggatc aagctcgtaa ggaccagtaa tattctttgc tcggcaaact
     3961 gtaactgaat gtcctcttcc tgtaccgcct tctgccgtca tcaaataata atacccgtta
     4021 cgaaaataca aatgtggtgc ctccgttttc gctaattctg tacctgcaaa tattttatag
     4081 atgggaccat caagcttctt cttctctgca tcatattctt gtaatacgat accgctggat
     4141 ttattcggtg tgtccagacg ataatcccat agttcattga caagccattt ttttcccgtt
     4201 tcaagatcat ggaacaaaga aggatcaaag ccgttactat ttaaataaat tggttcggac
     4261 caaggacctg tgatctcaga tgcagtgatc aaataattgt ggacatcttt aaacggacgg
     4321 cctgcacttt tgacatctgt gtaaacaaga taaaacaatc catcagcata actgatctgt
     4381 ggcgcccata tacttccatt tgtaggattt ccttgcaaag atacttgagt ggtcaaaata
     4441 tccgttgtat gtgaccagtt gactaaattt ttcgactcat atactcggat tcctggaagc
     4501 cattcaaaag aggagacaat aatgtaatac cgctctttca ctcttaatat attaggatct
     4561 ggattgaatc ctcttaaaat aggatttttc actttgatag tctgcatgat tcaggctcct
     4621 tttctcattc ttactcgata taaactgaat gccccagctg ctaaaaaagc aagtgaaata
     4681 aacaacacaa cggcaaacag accagtcatg tcctgtaata atccaaatgt attttctaaa
     4741 gacaaagttg aatgatctac agcaagcgac tgataacttt ttttaaactc tgacgcagac
     4801 atattactta aagtaactgc taacccgcca aagaaaatca aagatagact gccaccgacc
     4861 attcctagca atagttccca ttttcttttc atttctgaac cccctgcttt tctaaatgta
     4921 tccattcagg tcttttgatc gatgtttcat aattgttatt acgttcagag aatttgacag
     4981 tctgttcatt tttcttgtca tcccaattat cccaaccagt tgggtgaaca tgcccaccta
     5041 tcttacacgc ttcaaataag acatttgcat acggacgcca cggtcttcct aaatagacgt
     5101 ttctagtatc aggttctgca gtcaaggtac agctttcaaa acgataccct gttttttgat
     5161 ttttcggcgt agatgctgct gtgatgtatc caggattttt actggctaag ctatggatat
     5221 gacactgatg aaaaacggca tctgccccac caaatatgaa atccaccgtt ccttcaatcc
     5281 agcaatattc ataggtctga cgacaatact caggattggc agaagccggt gtacaaaaag
     5341 gagtaccatc tttttgcaaa tcaggcaacg gacccgtgca taaggtatcc tgataaccag
     5401 atagtcgaca gttttttaaa gatacgcgat ctcctgaatt gaataaagca acagcctgtc
     5461 ctaccttttc tcctggacct gctgtatttt cgatgtgaag attttctaat acgacattcg
     5521 atccttctaa gaaaaaagta gcacttcgga aagtccctaa ctggctaccg tcaagatact
     5581 cctgttttgc aaaacgatta ccggagataa ctactgttcc tgctcccaca agtttaaaat
     5641 tggataatct gctttctata tattcatcat atcttccttc ttttactatc aagacctttg
     5701 gatggctatc cggcaggcct gccaaataat cgattccttc ttggatagtt tcaaaatccg
     5761 tcggggtatc tatagcattc tttccaatta tcagtttgtc tttcatcctc ataaatgctc
     5821 ccttatgaat tgtttccaaa tatttctcat ttcttgtgtt tccatatgac cgcctgttaa
     5881 agaaaaagaa gaaaagtttt ctggactacc cattgattga tactttttgt ccagcccttt
     5941 tctcagcttc agtacgcctt cgtccaagca catcgtatcg ttttttccaa ctaagctaag
     6001 acgagggcgc ggagcgattt tttcttggat tgctaacgtt gtataagctg tcaatagatt
     6061 tggcacatag taataaaacc catgatgatc taggcggcga tgtagcaaaa gtgtttcgat
     6121 gtccacctgt gccgctagat caatacaaac tttgacacga gaatccaatg ctgtcaccca
     6181 ccagcttaat aagcctccca tagaaagacc aatcgttgcg agccgttgag tatctgtgtc
     6241 ttcccttgtc tccaaataat cgatcaagct gatcacatca taaatacgca ttccccataa
     6301 cgtttttcct gttaataaaa attgtttgaa caactcgctt tcagaaatac ctccgcgttc
     6361 ttcaaatccc caagcatcaa tcgaccaaac agcatatccc attcctgtca gtacttctgc
     6421 aaaagatgga gaagctaagt aaggagcacc atggatcaat tcacttttcc cgactgaaaa
     6481 atctccgccg tgagaatgca ggtaaaggac cgtcggaaac ggtccttctt tttctggata
     6541 agcatagagg gctggtactg tttccaattc atttaagtac aattgatagt attcaagcat
     6601 aaaaccgttt tgtttttctc ggtataatcg ttttccacta ggggtatgtc tgctagatgg
     6661 agcacctaaa aaatcattca actgcataag caaagttttt acgaacaacc agttcatcca
     6721 tattttctga ttgatttgat tggaatttct caatactgat ttctttagta ttttctaata
     6781 gaaatgctgg tccctcgtga ttttcaatcg acatctggtt aaaggaaacc ttacccgcaa
     6841 agccaatata aaatccttgt ctgctcattt cctctattcc tgtcatcata gcaggaacac
     6901 cgggaactgc atcttgggcc atcgagacat cgatattgtc aaatgtgatt tcttgtatga
     6961 attgttccgc taatccataa ataaaacctg cagaagcatg gacattcctt gccgtgatat
     7021 tcgaaaaatg gatccttctg aatgctgatg tccgttcatc tatcggataa gccttttttt
     7081 cccatacata cggttctttc cctcgcggac cacagaaata ataaagattc agtataaatg
     7141 gacacatcac attatccatg actatattgg atactcgaat atcttcaacg atcccgcctc
     7201 gacctcgtct agatttcaat cgtattcctc gatcagtttc ttggaagata caatttgaaa
     7261 tggtaatatt acgaatacta ccactcattt cacttcctaa tacgacaccg ccatgtccat
     7321 ggaccatcgt gcaatttgtg atcgtgatat tttcgcaagc gatcctttcg tacgtatctt
     7381 cagtccctgc cttgattgca atacagtcat ctcccacgtc aatatggcaa ttactaatac
     7441 gcacattttt gcatgattct ggatcaattc cgtctgtatt tggtgaatcc gctgggttca
     7501 agatcgtcaa gttatcaaac gttgcattac tgcaaagaat cgggttgatc gtccaacttg
     7561 gtgactggat caatttaata tctttcacag taattcgatg acagttatgg aaactcatca
     7621 atttaggacg aggataagcg agattatctg gttcatttct aaaagtatgc caccattttt
     7681 ttccatttcc atctaatgta ccgaaaccag tgacagagat gttctctaca ttttgagcat
     7741 agatacagga agcataaact tttcgatgga ctccttccca acgtgaatga acaacaggat
     7801 aatcttttgg atcgtcagag aatttcagaa ccgctcctgc gcttaaatga agttcgacat
     7861 tgctttttaa aaataaagct cctgttagaa attcacctgc tggaacaact acggtcccgc
     7921 ctccgtcact tgctgcagca tcaatggctt gttgtattgc ttcagtattc aattcatcaa
     7981 ttgatgcgcc aaatgtcaaa atatcataca tatttataat gcctccactt caatcaatgc
     8041 ttgcaagaat gcaccaacgc ctttttgatc attacaaata attggttcac tgatgtagta
     8101 agcatatgaa ccatctcgct gatctgctcc gcctaaccct gctacttgac agtttttatt
     8161 caagttcagc cagccttctt ttgtttccag aacaaattca tcaagtaatc cttgatgtga
     8221 tttcttcact tgtggaagcc attcttcttt gttcagcagt cccaaacgta ttcctttagc
     8281 cattgcgtaa acaaacatac tactgccgga agcttccaga taatttcctt tccgttttgt
     8341 ttctgttgtt acttgatacc atgtcccgct gttttcttct tgatatggaa gtaatgcagc
     8401 cagtgtcttt tctagaattt ctttcagcaa agaacaatct gtttcttcat gaagtaattc
     8461 ataggtatct gctgcagcca tcaaatacca gccaatcgat cggctccaaa aatgatggga
     8521 tagacctgtt tttggatcag cccatggttg gaccttcttt tcatcccatg catgaatcag
     8581 caaatttgtt tttggatcga atagatgttt ataactgatt tcaaactgtc tcaaaacatc
     8641 ttggtaatct ttttcttcac taaaattctg gataaattca gcataaaaag gagaacccat
     8701 atataagcca tccaaccaaa tttgataagg ataaatttct ttatgccaaa aagctccttc
     8761 ggatgtgcgt ggatggtttg ccaactgctg ggaaaggagt tctgctgctt ttttatattt
     8821 ttcttcgcct gtttctttgt acaataaaaa gaaaagcttt cctgtattta catggtcgat
     8881 attgtattct tcaacgctgt agccacggat cgttccatct tcttgcacga aatagtcgat
     8941 attgtctttt atgaaatcaa aataaatttt ttcttgggtt cgttcccaaa gtaattggaa
     9001 ccctttaagt acgacgccat agtcataaga ccattttcct ttataccact tttcttcata
     9061 taagcgaggt gttctttcca tgatactttt tgctaatttc tttgaccagt tttccattat
     9121 ttgctctcct ttaaaaatta aaataggatt tgggacaaat accaagaagt atttgtccca
     9181 atcgtctata ttactgtgcc gctgctttgt atgcttcctc gtactcttgt gtgattcgat
     9241 cgcctccttg tgctttccag tcttctacag cttttttgaa tccatcttcg tcaagctgtc
     9301 ccatgatgta ttgcaccgta gcatcaatga cgattttttc aatttctgat cctacttcat
     9361 tgttcgtcgg tgaatccaat ggcacagaag gatccattac agcaaattct tcattttctt
     9421 tgatcaattg attagagaat tctttttcag ggtctgtatc tttgaaagag aacgtcactt
     9481 cactaggacg agagcttgat aacggttgca cctcttgttg ccaaagatcc atatcgataa
     9541 attcgataga accatcatca ttcaattcat aatgcgttcc ttcgataccg ccagtcatca
     9601 atttatacac atcttcttct aaaagatcat caacaaattg aagtaatttc ttcaattgtg
     9661 cttcgtcttt tacttgagat ttgggaaatg ctagcaagcc gccaatacca tttccttctg
     9721 accaaacatg ataaccgccg ccttcaccat ctgagatctt gtttacaggc actaattcca
     9781 tatcatcttg aataccttga cccatcgtct tcagattctt gatatccacc attccagtgt
     9841 agattccagt tcttccttgt gcaaattgtt cttgctgatc agtcttttgg gtaactgcaa
     9901 agtcttgtgc caaatagcca ttctcaaata gatctcttga aaaattcaaa gctttcatat
     9961 actcttctgt atcaaattct ggagtgaatt tgccattatc gtctacagcc cagccatttg
    10021 gtgctccaaa ataagaagtg aaaagtttaa agctggtata acgaatatca ctaggcgcac
    10081 gatcgccaaa accaactgtg tcgtccacac catttccatc aggatcgttt tctgtaaatt
    10141 gtttagctac ttcataaagc tcatccatgg tagttggaac atctagtcct agattatcca
    10201 accagtcttt tcgaatgact aagccagcac gagcgtagtc tttttgtatc ggtacgccgt
    10261 acaaggcacc gtcgatactc gcagcttcga ttctatcttc agaaatttga cttaaatttt
    10321 tatagtcttt taaatattct gatacatccc agaatacgcc tgattttaac gcattgcgga
    10381 cagaagagtt tttcaacatc gcaatttgaa gtgtaacgat atctcctagt tcatcagaag
    10441 ccaatgcagt tgttaatctt tcttcttttg aagcatcagg aatccagttg aatgtcagtt
    10501 ccgtatcggt tttttcttcg atcaagttca caatcgtgtc tgtaggcggt gaagcatgat
    10561 gcaaaatatt taaccaagtg attttagctt ttccatcttc tgtctctgaa gaactgttac
    10621 ttgaactgct gccgcatgcg gcaagtgcta gaattcctgc aaaactaaga cctaatttta
    10681 cgagcgttgc ttttttcata aattttctcc ttcactgttt taataatatt tttgttttct
    10741 tctgtttttt ctgtatatga gttcttccat tccaaatggc aaaatataga atttgctgtc
    10801 cacgtgactg cggaaaagaa gagactgcca ccgataaagg ttaaaacacc tggcattgtt
    10861 tggatgatca tcagataaat ccctaccata cttaatatca acactaatga gtaatgaaga
    10921 tgtgagaatc cgaataaaaa tgccattttc attttgaaaa aatatccttt ccaatcataa
    10981 tgagccatga ttgggaaaat atagagtgct gagagcacat atatgaacgc agcaatatac
    11041 aaagcgatcc taagatacca attgtgtatg aaagaaagat ccacaagtaa aacaatcccg
    11101 atggcgccat atatccagct catcagcaag gtttcacgat agttttcttt aaaatatgtg
    11161 aagtacgttt tcgtcaaagg aaacgtttct tttgagcgca gccattttct aatcactgca
    11221 accatcgcat acgatgcagg accgaaagta aaaactccca aacctgcgat gactaaaccg
    11281 ccccacagaa aattcaaata aaccaactgt aaaatacgat ttagccttcc gtttatttta
    11341 tctaatgact gcagcatatc tttccctctc tttctatctt agtaaacgcc gtcttctcct
    11401 agctttttgg caatcttatt agctaaaatt accataaaca atcctacgac ccctttaaac
    11461 aatcccattg ctgtactgaa acttaactgt ccattcttca atccagctgt ataaatatag
    11521 gtgtcgaaaa tttctgcaac gcttcgattc aatgaattca ataacaagta catatgctcg
    11581 aaccctaagt ctaatgtctg accgattttt agaatcagca aggtaatgat tactggacga
    11641 attgccggca atgtaacatg ccatgttttg cgtaagcgtc ctgctccatc catttctgca
    11701 gcttcataca actgtgtatc gactgcagtt atcgctgaaa ggtagatgat cgtagaccag
    11761 cccaactctt tccagatcac ttgtccgata tatactgtgc gtgtccattc aggggatgtt
    11821 agaaaactga ttttttcaaa tcccattgtt gcaaggaatt cattcaatac ccctccgtca
    11881 acattcaaaa atacataagt aatcgaaaca atgattaccc aagacatgaa gtgagggatg
    11941 taaatgatcg tttgaatccc gtttttcaat cgtttgttcg ttacttcatt taatagtaaa
    12001 gacaaaatga ttggcatcgg aaaaaacacg aagatattta atccgaacaa gatcaacgta
    12061 tttcttaata atgtaaagaa tgtcggttct gtaaacaaac gaatgaaatg tttgaaaccg
    12121 acccaaggac ttcccattat tcctaaaaat ggttgataat cttgaaaagc aataacgagt
    12181 ccccccatag gaagatacct aaaaatcaag aaataaagga ctcccggcag aatcatcaca
    12241 tataaaaatt tattcgtttt gattcctgca attatttttt ttcgtcttct gagcttttct
    12301 tcttttttcg atagcgtcag ttgaaatggt tcttgtttct ttacactttc cataagcccc
    12361 tccttagttt tgtgaatgtt tgctgcttat gacttcatga tagataacta tctgaattac
    12421 gtatataatc atttttatcg taagtaaaaa cgcttacata gcaatgattt ttgtgctata
    12481 caaaacgata aagtgtattt tttcacaaat aaactacgca tagcaaacct tctatttttt
    12541 tctatctgac acttagcata ggaaatgatt atatacgtaa tctttcaccg atgataaatt
    12601 gaacatatag aaacagaaac atttaattta ttttgaggag gagcctatct atatgaaaaa
    12661 gaaagtctct ataggagaaa gaagttttac acttttcaac aatacgtttc taattttgct
    12721 agctttgatc tgtatcgttc cttttttaaa tatcatcgct acatcttttg cttctacaca
    12781 agaagtcgtc gcgaaaaagt ttatcctttt tcctactacc ttttctttag acgcgtatcg
    12841 ctacattctt tctacgccga ccatttttag agcacttgct gtttcgattg gtgttacagg
    12901 tgtcggaacg atcgtcagta tgtgtgcaac ttcactgatg gcctacggtc tttccagaaa
    12961 gtatttgttt ggtcgaggtt tcgtcaactt tcttgttgta ttttctatgt tgttcagcgg
    13021 ggggatgatt ccaacgttct tagttgttcg ttctctaggg ctggtcaatt cttactgggc
    13081 catgatcctg cctgtggctg ttaatgcaat gaatatgatc attatgagaa actttttcca
    13141 agccttgccg gatagtttgg aagaatcagc aaaaatggat ggttgcacag attttggtgt
    13201 atttttcaaa attatgctgc cattagcttt accgtctatt gctactatct cgctttttta
    13261 tgctgttact tactggaaca cttatatgac tgctattttg tatatcaacg attcatctaa
    13321 atggccgata cagattcttt tacgccaaat cgtcattgta tcaagtggga tgcaagcaga
    13381 aagtagtgcc gttgatgtga ttccaccagc acaaacagtt aaaatggctg ttatcgttat
    13441 tgcaacagtg cctatgctga ttgtttatcc ttttgttcag aaatattttg tcaaaggagc
    13501 actcgtaggt tctgtcaaag ggtgattatg tactgaacgc aaaatggtag ttgtgtcaga
    13561 agtggtcagc ttcaagaaat aagaaggcat ttacgaaaat tgcttcttaa atttttgtga
    13621 aatttcggct tatttttcga agaatctact cctggaacac cgtgtatcag aggttgtgaa
    13681 agagacgttc agccttgagc gatgataaaa actctcacaa acattgcgac gagtaaccca
    13741 caggagcaat aagaagcgat tttgaaaaat agcttcccat atttcacaaa attatgcctt
    13801 attgtcgata gcctgtctct tgaacgccat ttattcgtaa aaaagaactg tgacaagact
    13861 tttgtcacag ttctttttgc gtgcttagcc ttgaaattta actatccata aatacaaata
    13921 ctagggttat tctaacttct tttattgctt gaatcagtcc acaagaaaaa cagcctcttg
    13981 attaaacggc gtttatcttg ttgattctgc ggcaataaaa tcagccagca gcaaaacatg
    14041 aagtgctgtt ttttgctgtc ctcttttatt gcttgaatca gatcacaaga aaaacagcct
    14101 cttgattcac aaatattttt ttcgatattc tcccggcgta atcgattcct tctttttaaa
    14161 gaaacgaata aaattttgcg gatttcgata ttgcaatctt tctgcaatct cttttacgga
    14221 gaggttagtc tctttcaacc atttttttgc tacctctaaa cgatgatttt gaacaaaatc
    14281 accaaatttt tctcctgttt cctttttaaa tacattactt aaatagttag ggttataatg
    14341 caacctatca gcgatcacat ctaaagacag atcacgatca tattctgtgt agacgatatg
    14401 cataatattc tccgacaaat ttttaaattc atgatcagtg attgcttgag agcattctgt
    14461 gattggcaga actaattgtt ctaaaacaag tttttctagt tctttgggat gataattgtt
    14521 cagtgctttt acataaattt gtttcatgtt atcaaagttt tttgaatcta ctcccaataa
    14581 ctgtcctaat tgaacgagtt cattgatcaa gcggaccgaa actacttccc gactcaaagg
    14641 atttttattt tgtgcaaaca atgcatcaat caattcatgt actaaattct tcacttcctg
    14701 atttccagaa cgaatggctt caaacaatcg attttgttct tctatcggat atctaataag
    14761 tgttttttca tgagcagcag gaacgatttc ctgataaaaa ataattgaac ttggaccagt
    14821 atttacacga taatacaggg cttcttttgc ccgatcaacc gattgcttgc tttcattcag
    14881 cgtttcgaac cggttactga tgcctatact gatagttaaa ttcaagtatt cttttacacg
    14941 tttttgaatg agtcggcaat actccatgac ttttttgctt gcttctgcat catctttatc
    15001 cattcgataa atagtggctt gcatttcttc attcaaaacg atcggcagca ttcgattttc
    15061 ctttggcaca atttccgtga tcatgttgtt gatcgctaaa agtagcaaat cacgctcccc
    15121 accgtgacta tcttctaaca gatcgatttg aaccaaagct gtataatagc agtcattttg
    15181 agaactataa ccaaattgct gcaaccgctg atctagttct cgcctttcta ctcgatttct
    15241 aaataaacta agtacaaata gcgtttccag ctgtggcttt tgggtaacta agtgtgcact
    15301 taacgcttct ttttctccta tgatccgact gactgattga gcgaccaaat ctagttcttt
    15361 cccactgaat ccttttgatt taagattcag acgttcctgt atttgagaaa tcggacgggc
    15421 aaatctgtcc gaaaataagt aggaaaaaag accaatgagt cctaccagtg ttaaagacac
    15481 tgcaactagc ccgattctca gattgcggat cattgcgcca attgcactag agtcaacttc
    15541 taatctgtaa atccaattat tataatctga tttcagtact atatacgttt tatctttttc
    15601 tcttatcact ttcagctgat tgtaatctag atccacgtcc gttaatacag ttggttgctc
    15661 tttatttttt actgtctgag tagtaaaaag gttgccaact tcgttttcaa tagaaagtat
    15721 gtcttctcca ctttcaccaa caacttgttc tattgtatgt ttctctatcg tagcaattcc
    15781 caatgcatat ttttcttttt caaacattgg caaagaaatc accatttcga ttcctttgtt
    15841 tttcttttgc caaaataaat tatttttgtt atttatgtac ttctgttgat acttttcaac
    15901 ttcctcttcg gtcagttgac tcaacgatcc attgattact ccccatttac cagccaaact
    15961 gactaaatca taattattat catccataac aatcgtttct ataaaattta gttctttcct
    16021 gatttcagaa taagtggagt aatctgtata tgtcagcgga tgcttgaata tgtccgagaa
    16081 atttttggtc gaaccatacg tagaaaacga atattcaatc gttctaattt tccattcaac
    16141 gttagtttta acttgcctga gcaaattctt tttgtctgtt aaataactcg attcgatcga
    16201 ttcataggta ttctggtaaa tgaataaact aaatcctatg acaagtacgg ctcctaataa
    16261 aaacatcggt aaaaatattt tataaaatac tgtacttttc ttcattttct tcctctcctc
    16321 cttttaaaat aaaaggcttt catttttctg taaaattgat actcatctaa ttaaatgagc
    16381 attccccgct ttcaagaata gcataattaa aaataaaaat ccaagtaatt tttaacgtgt
    16441 gcaatctttt catatcaaag atctattgac ttatcgtagt tatcgtaata tgatgaatgc
    16501 gttaacaaaa agtgaaaaag taaggaaaat gatggaatgg taacgatcaa agatatcgct
    16561 aaagcagctg gcgtttctca tacgacagtt tctcgtgctt tgaataacag cagtttaata
    16621 aaaaatgaaa caaaacaaaa aatacgacaa ctagctaagg aaatgaatta ttcgccaaac
    16681 tatagtgcaa aaggtttagt gaatcaaaaa aaatatctaa tcggactatt tttctcaagt
    16741 ttgcataaag gaacttcatc aaatttccta gcagattcca ttgcaggcat ccattcagta
    16801 ttagacacaa attacagttt atctgttgaa agtatcgatg ttgttgattt aacagaaatc
    16861 aacctgcaac gctacgatgg actgatcgtt atgagtcaaa gtgatgatga tcagcctttc
    16921 atcgactatc tcaaagaaaa agaatttcct ttcgttgttg tcaatcgtca catcaatgat
    16981 ccagcggtta tcaacgtcac tgccgatgat gcggccggtg ttatgcaggc agtagattac
    17041 ggtattggat gcggacatac gaagatcgct tatattggcg gaaagaaaaa ttttcgttcg
    17101 acaaaagaac gggaaaaagg ggtattgaaa agtctaaaaa aagcgagcat ccctgtcaat
    17161 ctagcctatt ttttaacagg agattacagc ttagaaagcg gcctccaaaa catggaatac
    17221 ctattatcac tttctgacct gcctactctg gttttttgcg gcaacgacga catagcgatt
    17281 ggtgcattga gagctgtaca tttagctggc ctccgtgttc cccagaacat ttctctgatc
    17341 gggttcgatg attctccagt cgtctcctat ctcaatccgc cgcttaccac cgtacgtaag
    17401 cctttgaaag aaatgtgtca agaaggaaca aagcttttac tagatttgat cgaaggcagg
    17461 acgatcgaac aatctaaaat tgagctctcc accttgttga tccttcgtga gtcgatcaat
    17521 tacttgtaaa ctacaagtaa ttttatataa aaatgttaac gtgtgcataa cacagaaagg
    17581 aagtttatat gaaaaaactg acaaaagaat tagtgaaaaa aaacgaagca cctgtaaaag
    17641 ttcttcagtt tggtgaaggc aattttatgc gtggatttat tgattggcag attcagcagc
    17701 tgaataacca acaattgttt aaaggtaatg ttgcaatcat tcaaccttta gaacaaggtc
    17761 ttggaaatat gatgaaccag caagataatt tatatacggt cattttacaa ggactcagca
    17821 atggcgaaat cgttgatact tccgagatta tcaccgtagt agaacaaatg atcaatcctt
    17881 atgatgaatg ggatgcttat ctatctctag cagaaaatga cgacttggcc tatatcgtct
    17941 ccaatacaac agaggcagga atccaattcg tggagactga taatttaaca gatactcccc
    18001 cacagagctt cccgggcaaa ctgacagcct ttttataccg acgtttcaaa ttaaacaaag
    18061 ctggctttac catcattcct tgcgaactga ttgacagaaa cggcgaacgt ctaaaagaaa
    18121 tcattttacg ctacgcagaa aaatgggatt tagaacctgc ttttgttgag tggttagaaa
    18181 aagaaaatgt tttctgttgt agtttagttg atcgcatcgt cccaggttat cctcgcgaag
    18241 atgcaggtgt tttcaatcaa cggcataact atgaagatca attgatggtc aaagcagaac
    18301 cattcatgct ttgggtgatc gaagggccta aagaattgga gaatcaacta ccattcaaac
    18361 aggctggctt gaatgtcatc atcacagatg atatgactcc ttatcgtgaa cgtaaggtgc
    18421 atttgcttaa tggaccgcat acagcgatgg tccctcttgc tttgttggcg gaattggaaa
    18481 ctgtagaaga agtaatgaaa gatcctttat tctccgcata tgttgatcag ttattcaatc
    18541 tagaattgat tcctatgctt tctttaccta aagatgaatt agccatttat gctgaccaaa
    18601 tcaaagaacg tttcttgaat ccttttgccc atcacaaatt agaagcgatt tcattaaata
    18661 gtgtttcaaa gttcagcacc cgtctgcttc cagtgttcaa gaagtatatc gaagaacaaa
    18721 atcaggtacc accgttaatc actgtttcac tagctgcgct acttcttatg tatcgaggcg
    18781 atcaagtaaa gccacatgat gatgaaaaga cgataagcga atttactgat gcttggtctg
    18841 ataatggaac agctattcct cgattattgc aaaacgctgc gctttgggga gaagatttgt
    18901 ctcaaatacc gaatgtgaca gatacagttc aagaaatagc tgcaaagatc gatcaaaaag
    18961 gtgtccggtc agtattacaa gaaatgaaag gaacgatggt ccatgcttga aaccctgcaa
    19021 ccaacaatga aattaaatcg acgagacagt gtggtcgtcg cattaacccc tattccaaaa
    19081 caaacacaac tgacgattga tcagcaaacg atcaccactc ttgaagatat cccgcaaggt
    19141 cataagattg cattgggtga tttgaaagct ggagacaacg tgatcaaata tggctatcca
    19201 atcggtcatg tgacgacaga cgtaactgcc ggtcaatggc tgcacactca taatgtaaaa
    19261 accaatcttt ctggtgaatt ggattatcga tatgaaaaag atgtccatcc aagtcattac
    19321 ctttttgaga accgaacatt tcaaggttac ttgcgaaaaa atggaaaagt agggattcgt
    19381 aatgatttgt ttttagtacc taccgttggg tgtgtgaatg gcattgctga actgatcgtc
    19441 aaacagttca aggaaaaaca tccagatctg ggacagtttg accatattac gattttaaag
    19501 catccttatg gctgttcgca gcttggaaaa gatcatcaaa atactcgaga aattttagcg
    19561 gacgcagtaa atcatcccaa tgccggagga gttttagtat ttggattagg ttgtgagaac
    19621 aatacagttc ctgaattcaa aaaaatttta ggtgaatatg atgaagaacg agtgaaattt
    19681 ctagtggctc aagatgttta cgatgagatc gaacaaggtg tggctctatt agaagagctt
    19741 ttaacagcgg cggaaaatga ccagcgcata tcagtcccgc tctctaagtt gaatgtcggt
    19801 ttgaaatgcg gcggttctga tggtctatcg ggaataactg ctaatccttt acttggtgca
    19861 ttttctgact acttgattgc tcaaggaggc agcacgatct taacagaagt gccagaaatg
    19921 tttggcgcag aacaagtatt gatggcacga gcggaaaatg aagaagtttt tgactcaatc
    19981 gttgacttga tcaatgactt caaacagtat ttcttgtctt acggggaacc agtttacgaa
    20041 aacccatctc ctggtaataa agcaggtggg atcactacat tagaagataa gtctttaggc
    20101 tgcacgcaaa aatcaggaag ctctcctgtc gttgatgtgc tacaatatgg cgaaaaaatc
    20161 agaaaaccag ggcttagttt attgcaagct cccgggaatg atcttgtagc tgcctctgct
    20221 cttgcttcat ccgattgcca gttggtcttg tttaccacag gaagagggac tccgtttggc
    20281 tcatatgtcc caacggtcaa ggtatctacg aatacaactc tttttgaacg caaaggtcat
    20341 tggatggatt ttaatgcagg cgtcttatta gaacaaccaa tggaagtaat cttagaatcg
    20401 tttgttcaaa aaatcatcgc tgtagctagt ggagaagaaa cgaaaaatga acaaaatgac
    20461 gttcgagaaa ttgccatttt taaaaacgga gtaacacttt gattttcata aaacagtata
    20521 aaaagaaaga aggaagattt atgtttttat ctgatgattt tttattaaaa gacgattggg
    20581 cgaaaaagct ttaccattcc tacgcaaaaa acatgcccat tattgattat cactgtcact
    20641 tagatccaaa agaaatttac gaaaacaaca atttcagcaa tctgacagaa gcttggttag
    20701 gaggcgatca ttacaaatgg cgcttgatgc gagcttgcgg cgtgcctgaa gaaaaaatca
    20761 caggaaatgc ttctgatttt gaaaaatttt tagcttggtg tcaaaccgta ccaaaaatta
    20821 tcggaaatcc gctttacagt tggtcacatc ttgaattgaa gcgtttcttc ggtattgact
    20881 tgttgataaa tgaagaaaat gcagagaaaa tttggacaca agcaaatgaa attttggcag
    20941 ctcctgattt tcgccgtcgg gaaatcgcaa aaaaatcgaa tgtagaagtg atttgtacaa
    21001 cagatgatcc cgcagacgac ttgcactatc atcagttgct tgctcatgaa gaaccagatt
    21061 tgaaggttct accttcattc cgtccagata aagcactcaa tattgaaaaa gaaggattta
    21121 atgcatgggt cacactactg gaagaagcag ctgaccaaac gatcaccacc tatcaagaac
    21181 tgatagaagt cttagggcag cggatagaat acttccatca acatggatgt cgtgtttccg
    21241 accacgcttt agacatctta cgctataaag aagcggatga aacagtatta gaagagattt
    21301 ttcaaaaagc acgagctaac aaactattat cttcagatga aatcgatgct tatcttacag
    21361 aaacactgat acatttgacc cacttctatc attctcataa ttggacgatg cagctgcaca
    21421 tccatgctta tcgtaactgt aatacacaaa tgttggaaaa attagggccc gataccggct
    21481 atgatggaat gaatgatctt tctttgacta ttcctctgca aaaattattg aaccgtgcag
    21541 aagaaacgga tcagttgcca aagacgatcc tttattcatt gaatccgaat gactatcctg
    21601 cgattttagc tttgatgggc tgtttccaaa aagaacagaa tggaaaactg cagttaggtt
    21661 ctggatggtg gtacaacgat actcgagctg gtatgcgcga tcaattgaca caatttgctg
    21721 atggtagtgc tttggggaat tttgtcggca tgctgacaga ttcaagaagt ttcctgtcct
    21781 acactagaca tgaatatttc cgtcgtgttc tttgtgaatt tttaggcgaa atggtcatgc
    21841 gaggagaagc acctgaagat gaacaacttt taggaagtct agttcaagcg attagttata
    21901 caaatgctaa aaattacttt ggcttttttg cctaattgat taatagtaac agtaacgaat
    21961 caaaaacagg atagtgaaat aacggaatcc gtttatccac gttttagaga agaagacgga
    22021 ccaa
//
LOCUS       DAZKCW010000042        22009 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000042 DAZKCW010000000
VERSION     DAZKCW010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.042"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(40..1431)
                     /locus_tag="ACG84Z_001881"
     CDS             complement(40..1431)
                     /locus_tag="ACG84Z_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162694.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            1688..5077
                     /locus_tag="ACG84Z_001882"
     CDS             1688..5077
                     /locus_tag="ACG84Z_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFP9162695.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            5080..6501
                     /locus_tag="ACG84Z_001883"
     CDS             5080..6501
                     /locus_tag="ACG84Z_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFP9162696.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            6498..8375
                     /locus_tag="ACG84Z_001884"
     CDS             6498..8375
                     /locus_tag="ACG84Z_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFP9162697.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            8467..9309
                     /locus_tag="ACG84Z_001885"
     CDS             8467..9309
                     /locus_tag="ACG84Z_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9162698.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(9461..10336)
                     /locus_tag="ACG84Z_001886"
     CDS             complement(9461..10336)
                     /locus_tag="ACG84Z_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFP9162699.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            10543..11574
                     /locus_tag="ACG84Z_001887"
     CDS             10543..11574
                     /locus_tag="ACG84Z_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9162700.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11663..11968
                     /locus_tag="ACG84Z_001888"
     CDS             11663..11968
                     /locus_tag="ACG84Z_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFP9162701.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            12147..14162
                     /locus_tag="ACG84Z_001889"
     CDS             12147..14162
                     /locus_tag="ACG84Z_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFP9162702.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            14164..14448
                     /locus_tag="ACG84Z_001890"
     CDS             14164..14448
                     /locus_tag="ACG84Z_001890"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9162703.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            14474..15847
                     /locus_tag="ACG84Z_001891"
     CDS             14474..15847
                     /locus_tag="ACG84Z_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFP9162704.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(15930..17945)
                     /locus_tag="ACG84Z_001892"
     CDS             complement(15930..17945)
                     /locus_tag="ACG84Z_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFP9162705.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(17967..19181)
                     /locus_tag="ACG84Z_001893"
     CDS             complement(17967..19181)
                     /locus_tag="ACG84Z_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9162706.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            19402..20346
                     /locus_tag="ACG84Z_001894"
     CDS             19402..20346
                     /locus_tag="ACG84Z_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFP9162707.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            20642..21586
                     /locus_tag="ACG84Z_001895"
     CDS             20642..21586
                     /locus_tag="ACG84Z_001895"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFP9162708.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
BASE COUNT         7490 a         4014 c         4143 g         6362 t
ORIGIN      
        1 tttatcaggg tggtttatac atagctgttt tttgattatt cataactcga ataagcggat
       61 gagttcttct tcatttgcga atgacacact atcatcaatc aatatatgag gaacatgggc
      121 attcaaaatg ggttgattcg taacgatcag atcatactcg agaagattgt atttcgacag
      181 ctgatcttca gtaatagcag ttgtctcaga gtgaatttta tgcacagcaa gaatatcact
      241 gatatattct tcaatatatt gactatgtcg aagacttaag tcgctgataa tcagtatttt
      301 tttatcagaa gtataatggt gaatttcagg attaccgata agcatccaaa agatatagct
      361 agataaataa taaatcagat tctgattcag tagagtggaa taaaattgaa gttctgcacg
      421 aaatccagca tatagacgta tctggcggtg ttgcatctgc tgtgcaaagt aagttgcacg
      481 gatcgtcaaa tgagtcgtat cgtatgggaa aatacgggag aaaaaataaa tttgcgttaa
      541 taattgaaca acatattctt cgtttttttc tttgcaatca gcggatgaaa acgaacagta
      601 ggacatattt tttcgtatct gctcactgat ttcatttttt tctttctccg aaaattctga
      661 aaaaatcgta ttgacaaaat agttcactac ttttatatag ctgctgtact tcaattttcc
      721 taagagattt ttcaagatta agaagtcttt tttatcgata tttatcaact gtacataaga
      781 gtctccagct ttccattcaa atggagttcc ttgggattct ctcatgagat gcacaacaaa
      841 atacataata aagaaagatt gctcatatgg gctttcttcc tgaaacaaat tcatctgaca
      901 attattcttg accataattt ctttgatctt ctttttttcg attggaaatg gcaacgtgcg
      961 tcttccgtag taacttaaaa agaaaaaggt aacaaagata cgcaactgga gctcactttt
     1021 aaggctagtt aactgaaaac cttggtcaac gatcactttt aataaatagc tttctaaaat
     1081 ttgattgcat tgtttcaact tacgtgtaaa agaagaccgg ctgatggaaa ttttttcaca
     1141 ataatactca atcgttttac ccggattgac aataatctca tttaataaac gactgtttgt
     1201 agaactttgc gacatttcca tcagaacatt taaataagct ggtacattca aatgttcaag
     1261 acgatacccc aatttttgtg aagattgaat cgttacatcc gttccccagc ggattttgat
     1321 ctcttcgata taccttacaa atgtagattc tgaactacca attcgtttgg caagttcttt
     1381 tttagtcatc cacttgtcag aaatggacag aattcgaatg attttttcca tctttctata
     1441 gtttccttcc aacaacctga tcatatgttt ttctccctca acccttttct ttcaatgaaa
     1501 cgctcattaa tcgaaggaat caacttcata aatgaaacca attggtatga aaattggtgt
     1561 gattcccttt agcgcccttc gtataataat tatcatatta aaataaataa aattatgtaa
     1621 cgcctgttta ttttaataat tttcactatt cacgtcaaaa cagaaaaaaa gaaaaaggag
     1681 gggaaaaatg acgaccacag ggaagaaact gaaagttatt ttcatgctga taatattgag
     1741 tttatcaaac tttgtgccat tatctgcaat agcagacact acagatgatc caacagtttt
     1801 agaaacaatt tcagctgaag tcatttcgga tcagtctgga aaaaaagcac tgaacatcaa
     1861 gctaaatgcg aataacacca gtgctgaaaa gatagaaaaa gaaattggtc tagtcgaaaa
     1921 ttacttaagt gatgtggaaa gaaaagaagg agatggctat gcttatcagg taaatagcgg
     1981 gaaaattacg ttggaaatct catcaaacac taaacaaact atcgatctga gttttccaat
     2041 cgatccagca ctttaccaca gccaggcaaa caagctgatc gtcgataata aagaatatga
     2101 cattattgat gagacagaaa ataagaaaga tacagatgtg tcagtaccaa agccagacga
     2161 aatagaagaa gaatcatcaa aagaaaacga aaattctgtc agcccattta cattgcctac
     2221 attatccttg ccagctgtga gtgtgccatc taatcaaacg attcctacag aatatacaac
     2281 agatgatcag ggcacttatc ctaaagccag ttggcaacct acaggaaata caaatgttct
     2341 tgatcatcaa ggcaataaaa acggaacaaa tcaatgggat ggtataaatt cttggaatgg
     2401 agatcctaat gatcggaccc attcgtatat cgaatatgga ggaaccggta atcaagcaga
     2461 ctatgcgata cgaaagtatg caaaagaaac aagtacaccc ggattgtttg atgtttattt
     2521 gaatgctcgt ggaaatgtac aaaaagatat cacgcctctt gatctcgtat tggtcgtaga
     2581 ctggtcagga agtatgaacg acaataatcg gatcggtgaa gtaaagattg gtgtcgatcg
     2641 ttttgtcgat actttagcag atagcggtat cacagacaaa atcaatatgg gatatgtcgg
     2701 ctactcaagc gaaggatata gctacagtaa cggtgcagta cagatgggtt catttgattc
     2761 agtgaaaaat caagtaaaat ccattacacc ttcacggaca aatggtggta cttttacaca
     2821 aaaagcacta agagatgcag gaagcatgct atccgttcca aatggacata aaaaagtgat
     2881 cgttttgctg acggatggtg taccaacatt ttcctataaa gtacagcggg tacacgcaca
     2941 atcaagcagc aattattacg gaactcagtt ttctaatacg caagatcggc cgggaaatac
     3001 ttctctaatc tcaagaatct atgatgcacc tgaccaaaac aatctatcca gaagaatcga
     3061 cagtacgttt atcgcaacca tcggagaagc gatggcactc aaagaacgag gaatcgaaat
     3121 acatggtctt ggcatccaac ttcaaagcga tccggcagct ggtctctcaa aagcagaagt
     3181 agagtctcgt atgcgacaaa tggtttcatc agatgaaaaa ggcgatcttt actatgaatc
     3241 agctgatcat gcaacagata tctctgaata cctagccaaa aaagctgtac agatctcagc
     3301 aactgtaagc aatggacaaa taaatgatcc aatcgcagaa ccattcattt atcagcctgg
     3361 tacactttca gtcaagagtg tggggacaag tcctacaacg gtcactccat ctatttccat
     3421 agaaggaaat accatcaaga gcaatcagat ctatttagga aaagaccaag aaatccaaat
     3481 ccattaccaa gtgagaatcc aaacagaaaa tgaggacttc catccaaatt tctggtatca
     3541 aatgaacggc aggacaactt tccagccaaa cattgatacc aatgaattag ctgaattcgg
     3601 tataccatct gctaaagctc ccggagtcag tcttcacatc aaaaagttat gggaagaatt
     3661 tgacaacaat ctagctgatc gtccagatca agttactttt gagattcaac gggaacatac
     3721 gacaaatgct gcagcttgga aaaacggata tattcgaatc attaaaccag ctaaagatac
     3781 aacaaatacg tgggaacgtg cagacattga caaattatct gcaaatagcg gagaaagtta
     3841 tcaagagata ttatcactac ctcaatacaa taatcaaggt caagcattca gttaccaaac
     3901 aatcaaagaa ttacctgtac caggatacga ttctcaacaa atagatgcaa tgacatggaa
     3961 aaatactaaa caattcacac cgttaaactt gaaaataacg aaaaattcct ctacaggtga
     4021 aaaggatctt attggcgctg ttttcaaatt aacaggagat tctattgata ctttactaac
     4081 agatcatggc gacggaacct attctcttcc agaaaatgtc aaattgcaaa aagaaatgac
     4141 ctatacgctg acagaaacaa aagctccaga agggcatgga ttaagcaaaa agactacttg
     4201 ggaaatcaag atcgcttctg atggtacggt aaccattgat ggaaaaacag tcactacttc
     4261 cgatgatacg atccagttga ctattgaaaa tccttttgtt gaagttcctg tagcagtacg
     4321 taagtatgcg atgcaaggga cggacaaaga gataaatctt aaaggagcag cattttccct
     4381 acagaaaaaa gaagcaaatg gtacttatca gccaattgac agccaaacaa cgaatgaaaa
     4441 aggtcttgcc agttttgatt cactcacacc tggtaaatat cgagtcgttg aaacagctgg
     4501 tcctgccgga tatgatactt cgccgggaaa ttatgaattc caaatcgata aatatggaaa
     4561 aatcatttac acgggaaaaa ataccgagat gacaaataat gtatggacgc tcactcatca
     4621 aaatcgacta aaagcgtttg atctaacggt acacaaaaaa gaagacaacg gacagacatt
     4681 aaaaggagca aaattcagac tgcagggacc agaaatggac ttagaatcgc caaaagatgg
     4741 acaagaaaca gatacctttc tattcgaaaa tttaaaacct ggaacttata cgctgaccga
     4801 aacttttaca ccagaaggat accaaggtct aaaagagcca gttactatag ttatacacga
     4861 agatgggtca attcaagtgg atggacaaga tcatgaatct gttctgtcac caggagccaa
     4921 aaacaaccag atttctttag acatcacgaa tcaggcaaaa gtaccattac ctgaaacggg
     4981 aggaattggc cgtttaggaa tctatctagt agggatgatt ggttgtgcgt tttctatttg
     5041 gtatcttttt ttgaaaaaag aaagaggggg cagctaaata tgaaaaaact tggttggctt
     5101 agtatgtgtc tcttcttgtt actatttaaa ccagctttta ctcaggtagc aacagaaaca
     5161 gaaacagaaa tggttcagat tactttacac aaattgcttt tcccaaacgg gcaactgccg
     5221 aaaaatcatc caaatgacgg acaagaaaaa gctttattac aaacgtatcg aggattaaat
     5281 ggtgtcacat tccaagttta tgatgtcaca gattcttttt accatctacg ggaaaagggc
     5341 aaaacggtag aagaagcaca agcagagatc gcaaaaaacg gtgcgtcttc cggtatgttt
     5401 accgcagaag caacaactac aactcttaac aacgaagatg gtatcgcttc tttttctctg
     5461 gccgctaaag atcaagaaaa aagagataaa gcgtatcttt tcattgaatc caaagtacca
     5521 gaagtcgtca aagaaaaggc agagaatatg gtagttgttc ttcctgtaca tggacaaaac
     5581 aatcaaaaac tttcaactat ccatttgtat cctaaaaatg aagaaaacga ctaccctgat
     5641 ccaccttttg agaaggtatt agaagagcct agaaatgatt ttacgattgg tgaaaaaatc
     5701 acttattcct tgcatacgac aattcctgta aatatccttg actatcaaaa gttcgaattg
     5761 tcagatagtg cggatgaagc attaacgttt ttacctaata gtttaacgat ttcatcgaat
     5821 ggagaaaagc tgacagaagg ctttgtcata cacaagaaac ctcacggatt tgatgtttta
     5881 ttttcgatcc cttcgttgga aaaatatgct ggaaaaaaac tgaccatttc ttatcagatg
     5941 cagctaagca gtacagcaca ggcgaacaag gaaatcaaca acaacggaac actggatttt
     6001 ggttttggtg tcagtacaaa gaaagtctct gtatatacag ggagtaagca atttgtcaaa
     6061 atcgagacaa ataaaccaga taaacgatta gctggcgcag tattccttat taaaaacaaa
     6121 gcaggaaatt acctccagca aacagccaac ggatacaagt ggacaaagaa cgaatcagat
     6181 gcgcttcacc tgatttccga taaaaatggc gctttttcaa tttccgggtt gaaaacagga
     6241 agttatcgat taaaagagat cgaagcacct tctggttata ttttaagtga aacagaaatt
     6301 ccgtttacca tttcaacttt tctttctgag gataaagagg cggacagtat attgaaagta
     6361 gtcaataaaa aagaaaatag ccgtccattt cttccaaaaa caaacgaaac gaaaaataca
     6421 cttttaggcg ttgttggtat ggtattcgca agctttgcaa tctggttgtt tatcaaaaaa
     6481 agaacaggag tgaaaaaatg aaaaatcata aaaaaataaa cgttatgtta ggagtccttt
     6541 tccttatttt accattactc acaaacagct tcggcgcaaa aaaagtgttt gcagaggaga
     6601 cagcagctca agtcatcctt cataaaaaga aaatgactga tttacccgat cctttaatcc
     6661 aaaacagcgg gaaagaaatg agcgaattcg atcaatacca aggattagcc gatatttcat
     6721 tttcagttta taacgtcact caagaatttt atgcgcaacg agataaagga gcgtccgtgg
     6781 atgcagcaaa acaagcagtc cagtctttga ctcctggtac accagttgct tcaggaacga
     6841 cagatgctga tggaaatgtc actttatctt tacctaaaaa acaaaatggg aaagatgcag
     6901 tctacacgat caaagaagaa ccaaaagacg gagtgtcagc tgccgcaaac atggttttag
     6961 ctttccctgt atatgagatg atcaaacaag cagatggctc ttataaatac gggacagaag
     7021 aactagatac tatccatctc taccctaaaa atacagtcgg taatgatgga acgttgaaag
     7081 ttacaaaaat cggtactgcc gaaaacgaag cactaaatgg agcagaattt attatttcta
     7141 aagaagaagg aacaccaagc gtcaaaaaat acatccaaag tgtcacagat ggattgtaca
     7201 cttggacaac tgatcaaacc aaagccaaac atttcattac tggtcattct tatgacatcg
     7261 gcaacaatga ctttgccgag gcatctattg aaaaaggcca gttgatcgtt aatcatttag
     7321 aagttggaaa atataattta gaagaagtaa aagctcctga taatgcggaa atgattgaaa
     7381 agcaaacaat cacgcctttt gagatcctgg caaatagcca aacaccagta gaaaagacca
     7441 tcaaaaatga tacgtctaaa gttgataaaa caacacctca attgaatgga aaagatgtcg
     7501 caatcggtga aaaaattcaa tatgagattt ctgtcaatat cccattaggt atcgctgata
     7561 aagaaggaac gcaaaacaag tacacaacat tcaaacttat cgatactcat gacgctgctt
     7621 taacatttga taatgattct tcaggaacgt atgcttatgc cttatatgat ggaaataaag
     7681 aaatcgaccc agtaaattat tctgtcactg agcaaacaga cggattcacg gtttcagttg
     7741 atccgaatta tattccttca ttaactcctg gcggtacatt gaaattcgtt tactatatgc
     7801 atttgaacga aaaagcagat ccaaccaaag gattttctaa ccaagcaaat gtcgataacg
     7861 ggcatacaaa tgatcaaaca ccaccgtcag tcgatgtcgt tactgggggc aaacgatttg
     7921 ttaaagtaga tggtgacgtt acatcagacc aaacacttgc tggagcagaa ttcgtcgttc
     7981 gtgatcaaga tagtgacaca gcgaaatatt tatcgatcga cccatccaca aaagccgtca
     8041 gctgggtatc ggcgaaagaa tcagcaacgg tttttacaac cacaagtaac ggtttaatcg
     8101 atgtgacagg tctaaaatat ggcacgtact atctggaaga aacgaaagcg ccagaaaaat
     8161 atgttccatt aacaaaccgt gtagcattta ctatcgatga acaatcttat gtaacagcag
     8221 gacagttgat ttctcctgaa aaaataccaa ataaacacaa aggtacactt ccttcaacag
     8281 gcggtaaggg aatctatgtg tatatcggtg caggagtagt ccttctactg attgctggac
     8341 tgtactttgc tagacgcaag cacagtcaga tttagtcttt ttgcaagaat tggaaaaagg
     8401 agcagcggat tacgcaaatg ctcctttttc ttttattatc aaacagtcat cacaaggaga
     8461 acacaaatga aaccaaagaa aaggaaactt ctagatctgc tgatgctttt cttgcttctc
     8521 tcaggaatag ggatactagc ttatccattt gttagcgacg cgctgaataa ttatctggat
     8581 cagcagatca tctctcatta tcagcaacaa gcggtcaaag aaaatgaaga agtcatggct
     8641 aaaatccaag aaaacatgac aaagaaaaac cagcaattag caaaagaagg tggaaatcca
     8701 ggtgcagatc cctttactaa gaaaaaagaa cctgcgaaaa aggatagaac ctattttgag
     8761 aaacatacga tcggtatttt gacgatccct gagatcaatg tccatttgcc aatttttgat
     8821 gaaacgaata ctgtgctgct agaaaaaggt gcctcattat tggaaggaac gtcttatcct
     8881 acggggggag aaaatacaca tgccgttatt tccagccatc gaggactgcc tcaagcaaag
     8941 ttgttcacag acttaccgaa actgacttta ggtgattctt tctatatcga aatcaatgga
     9001 cggacactcg cttatcaagt cgatcagatc aagacggtag aaccgactga tacaaaagat
     9061 ctgagaatcg aaaaagggca ggatttcgtg acactcctaa cttgtacacc ttatatggtc
     9121 aacagtcatc gcttacttgt cagagggcac cgggttcctt atcatgcaaa agaagttcaa
     9181 aaagaagtac agaaagtatc cgagaacaaa cgatttttcc tgtatggatt gttagctgca
     9241 tgtatactga ttttcctcct tcttatatat ctttttcgtc aatcgttcaa aataagaaac
     9301 agaagttagc tattcctcat ttctataata tatctattcg aatcgttccg taaacaaaca
     9361 ggctgaggtt tgaaaaagaa aacttcagcc tgtttttatg atgatatcaa agagagccta
     9421 tcaaacacta tctttcttat tactaaatga ggatcttttc ttaagttttc cgatattctt
     9481 taagaaggcc tttttgcatc aattcttgtt tgtttttcaa gttgcggata ttctcttcaa
     9541 aattttgaga atatatcact gagaataacg tatttaatac gtaatcgaag gcaatttgag
     9601 aggagaaagt cgctacttta gcaaaatcat attcctcctg cgatataaca agacacatat
     9661 cagcctgttt ggccatttct gaatgctgat ttccggtaat cagcaaggta ggggcctcta
     9721 catgcttcaa ataggtcatt attcgttcat aatgatggat gcgaccgctg tagctaataa
     9781 aaatggcgca atcctcgcta gtcaaattgg ctgcattcca agaagaatca ctgtattctt
     9841 cagccatgat caaaaactta ttcaacttga ccattttatt ctggaatttc cttgccgtga
     9901 tttgagaatc accttttgca aaaagaaaga ttcgctgtgc cttgttcaat actttaccga
     9961 tttgatctaa atcttcatgt tcaatctgca attgtgcttt ttttattgac tggatcgata
    10021 aatccgccat tttctttgca atttgctgag tgctatcttc acttgaaaaa ggaaaattag
    10081 gatcaatcgt ttgattgaac tgagcaatca attgatgaac ttcccgcccc agctcgaaac
    10141 ggaattcttt aaatccgctg aatcccattt ttttgcataa acgaatgata gctgaatggg
    10201 aagtatacgt agcttttgct aattcttcaa tcgtcatgta gactgcagct tcgatattcc
    10261 tacggatgta atcgacaatc cgtttctctg tcgtggtaaa caactcttgt tttgttagtt
    10321 tttcttcaat aagcatgatc tgacctccaa attctatctt actgataaac acttggttcc
    10381 gctactatct ttttgatttt tatccttact ttgaacatta atttcaccaa accgaatgat
    10441 aacaagtgtt tttctgaact tttttaccag aatagctatt ataaatactt tctgcgcttt
    10501 tctaggatat actgaaaaca tcaataaaag gaggcaccac tcatgcttac aatcgcttat
    10561 cttggcaatg gaaagagtac aaatcgctat catttgcctt tttcaagaaa acttacgaac
    10621 aaaatcaata tcaaaaaaat tttttcccca tctgaaccag tgtggaaaac attcgaagac
    10681 atcgaatata ctgatcagct gtctgatctt tgggatgatc ctgagatcca attagttgtc
    10741 atcactacac ctagtcaatt tcattatgaa tatggaaaaa tggcactcga acatggtaag
    10801 aatgtactag tagagaaacc ttttgcagaa acgtcaaagg aagcagaaga gttatttgca
    10861 ttagcaaaag aaaaaggtct atttatccaa tgttaccaaa acagacggtt cgattctgac
    10921 ttcttgacag tccaaaaagt aatcgaaagc ggaaaattag gggatatttt agaagtagaa
    10981 atgcattatg attatttcag accggaagta ccagaaaata cgcatgaatt ttctactgcg
    11041 aacagctatt tatatggaca tgcttgtcat acagtagatc aagttctttc ttatttcggc
    11101 gaaccagatg atatcagcta tgatgtacgt caacttttag ggaaaggacg aatgaatgat
    11161 tacttcgatc tggatttttt ctatggaaat atgaaaattt cgataaaatc cagttatttc
    11221 cgcatcaaag aacgtccaag tttcgtcgtt tacggaaaaa aagggatgtt cgtgaaacaa
    11281 acaaaagatc gacaagaaga acatctgaaa atgttttaca tgcctgatca tgaagacttt
    11341 ggtatcgatt tgcccgaaca ttatggtgta ttgacctata tagatgaaca agggagttat
    11401 catgaagaaa aagtaatttc cgaggttggt gattacagcc gtgtctacga agggatttac
    11461 gagacattag ttaatggcgc agaaaaagtc atcaaagatg aagaaacaat cttacaaatg
    11521 aaaattttgg aagaaggaat caaaagcatt caagaatcag aaggaaaaat atgacatatt
    11581 tgtaagaatc gggtttgttt tttgacgcat aaactgtctt attgtacgat gaaaaagtat
    11641 agaactacta ggaggaacca acatgacaaa ttatgacggt gaaaaacaca aacgattaag
    11701 aggttcaatg gcccctaaaa cagaagaaga agtggcttta gcaggaacta attctggtga
    11761 aacagaagac aaagaagaat cattagctgg cacaaactct ggtgaaacag aaaataaaga
    11821 aacagcttta tctggttcaa attctgtaga agaggaaaca aagcctaatg agcccaatca
    11881 ctttgaaaaa gatatcgaaa aagcggttga agatgtcaaa gaaaaatttg aagaactgac
    11941 ctcaaaaaat aaacatgatc atcattgatc ggacgaaatc aattcataaa agcaggagac
    12001 atttggtcac ctgctttttt tctgtatcca ttcgatagaa atcgttcggt acagtcgtaa
    12061 aaaaaatcca actgtaagtt gtaccaaaca cccctcgatt taaaagcgct accatactag
    12121 aatataagta ggaggtgaac agcgctgtga actacaaaat tagttatctc ctgaaaacac
    12181 caagagaaat cagtctagaa aaagcagcag agatcatcga agtaaataca agcgaggcga
    12241 tcaaacaatt aactcctttt gccgaatatg tggatgatac ccgtatccgt ataaagaaat
    12301 tccgagcaat cgactgggca gaaaaatttt tggatattac tcgatttgaa gctgtgtata
    12361 ccgaacaaga gcgaagagat cttctttatt tgatggttta ttcgactgca acgtctgttt
    12421 ctgtttttca ttttcaagat tttcttcagg tttctaaagg gacagtcctg tcagatatca
    12481 aaaagataag aaatgaatta gaagtggaag attgtcagct gtcgtatact aggaaaactg
    12541 gttttaggct gctagggtca gaagcaatat taagaagaga agcaaaaaat cgcactgctc
    12601 gtttgatgca gtcacttgct ggaagatttg ggctcacgta tttaaccgca accctttcca
    12661 ttgattatta cgccaaagtt agagatttgc tagataaaac gatttcacta tcagatcttc
    12721 gattcgcacc aaatcgaatg gatgaattag cttattattt gagtttgaca accattcgaa
    12781 ttggaaaaac atccatggaa ctggtaaaag atgctgaact gttggcttct cttgcagtca
    12841 ctgacattag tcgacaagta ttgactggcc ttggctattc cgaacatcaa aattcggaga
    12901 ttatattttt ctctctttgc ttagcatcga tcgttgaagg agatgtccag gagcctgcac
    12961 ttgatttttt gctggaatgt tcttcagaag tcatccatcg catggaattc ctgatggccg
    13021 tagaatttgc ttcgtttcgt gaattattga tgaatgtctt ttatcacttg gtccctgcct
    13081 attttcgtat ttcctattct ttttatttac ctaatgtgat gatcgatcaa attaagcatc
    13141 aatatgcttc catctacgaa atgacaagaa aagcattact tccgttagaa agacgaatag
    13201 ggaagagcat ccctgaagaa gagattggtt ttttcactat actatttggc ggagagatca
    13261 gaaaagcgga cgcagaagaa agaaatagaa aaataagagc cgtgatcgtc tgtccaagtg
    13321 gcattagctc ttcattgatc ttaaaaagtg aacttcagca attattcccg atgatctttt
    13381 ttacagagac taattcagct gaccgcttac acgaggttga cgaaacttct tacgatatta
    13441 ttttttctac tgtacctctc acacttactg ataagaaaaa gtctctctat gttctgcatc
    13501 caatcatgac tgacttggaa aaaaatcagc tgatcaatca agtacaaaga gattggctga
    13561 taccaggatt ttcaatgcct tctgcccaag aattgttgtc ggcgctactg ccttatatcg
    13621 aattaaaaga aggcgtagac gaagaaaagc tctatcaagt attaaatcgt aaaatgaaca
    13681 aacttttaga aaagaaggag gatcaacgtc ctatgctatc tgaattatta acagaagaaa
    13741 tgatccaatt atcggatcaa ccaaaaaact ggcaagaagc aatcacattt gccgcacagc
    13801 cgctattatc agaaaataaa atagaagaaa gttatatcaa agctatgatc gagcgcgtgg
    13861 agcagtatgg tgcgtttatc catattggcg atcacatcgc attacctcat gctcgtccag
    13921 aagatggcgt aaacgaagta gggatgtctt tgctgaaact tcaacaacct gtggatctgc
    13981 ttgataatcc agcccatccc attagtttgt tcatctgttt agctgctatc gataatgagg
    14041 cacatcttcg ggctttggca aatttaacaa agctactttc taataaacaa aatcttcaag
    14101 atttattaca cgcatcaaca aaagaagaaa tattagcgat cataagaaaa ggagacgaat
    14161 gatatgaaaa tttttgcagt atgtcaaagt ggattaggaa caagttttat ggtagagatg
    14221 aacatcaaac aagcacttgc agatcttgga gcagatgtgg acgagtttga agtaagtcat
    14281 acggatgttg gaagtgtatc tagcgatatg gctgattatt tcttcattga gcattctttg
    14341 aaagatacgc taacttctat acctgatgaa aagctcgtac ctttgcaatc gatcattgac
    14401 agcgaagaag taaaagaaaa agtaacgaag atcttgtcaa aagaataaaa atgattcaag
    14461 ggaggaacta tcaatggata aattgttgaa tttgtttgtg tcaatcgtca gtcagccctc
    14521 catcctcgtt tctttgattg cactgcttgg tctcgttctt cagaagaaga aattttcaga
    14581 agtgatccaa ggaactatca aaacatttgt cggattccta gtactgatcg gcggtgctgg
    14641 tttaatcagt aattcactaa ccccttttgc ttcgatgttc caaacagctc tgcatactca
    14701 aggagtagtt cctagcaatg aagcagtagt ggcgattgct ttgcaacaat acggtacacc
    14761 tactgctttg atcatgctag tagggatgat cgtgaatatt ttacttgcta gattcacaag
    14821 atataaattc atttttctta caggtcaagc aatgctttat gtttcttgtc taacagcagt
    14881 cattttagta agcgcggggt ttactgcaaa tttgtggatg atcttattag gcggggtctt
    14941 cgaaggaaca ctattaacta ttacgcctgc tctttgtcaa ccgtttatga agaacatcac
    15001 tggaaacaat caagttgcgt tagggcatac cggaaatatc ggttatgctt ctagtggatg
    15061 gatcggaaag ttttttggaa acaaagaccg ttctacagag gacataaaga ttcctaaaag
    15121 tttcagcttt ttgcgagatt ctactgtatc gatcatgctc ttgatgtcga tcgtatatgt
    15181 cgcacttgct ttgttagctg gtcctggatt tgttgaaaga gaactaagca atggagacaa
    15241 cgctgtaatc tttgcactga tccaagctgg aacattcaca gctgggtttg ttatcgtcct
    15301 tcaaggggtt cgaatggtgt tggcagaaat cgttccagca ttccaaggga ttgctaaaaa
    15361 actcgtaccc gattctaaac cagcattaga tgttcctatc gtttttccat atgcacctaa
    15421 tgctgtatta attggctttt ttgttagctt ctttgtagga acactatcca tgtttgctat
    15481 gataggcttg caaactacag ttatcattcc tggggtagta ggacatttct tctgcggagc
    15541 tgcttctggt gtcttcggca actcgactgg cggtagaaga ggggcggtat taggttctgc
    15601 tttcaatagc ttattgatta gttggctgcc attatttatc cttccagtat taggagatct
    15661 taaaatcgct tcttctacat ttgccgatac tgattatcta gtaccaggac ttgtacttgg
    15721 gaaactagga gaatacggtc aaatagcctt gacagttgga atcatcgctt tctttttact
    15781 tgtcgtatta tctagctttc tttttgccgg aaaaagaaca aacattgttt ctaaagaaca
    15841 gaattaagca aacttcaaaa taaaaattgc ttggacaata tcagaagaag atttaaagtc
    15901 ttctgatatg tcgcaagcag ttttttgttt tatgcattta tttttgaata gcttgttaag
    15961 acaagtggct gttttgctag aagaggataa cttttaccat tcattttcac tgttccgcct
    16021 gttctatcag aagtaatcac gatcttatct tttgtttttt caagcgaaat ctttccatct
    16081 ttgataggta gcgtacaatt cagtgtttca aatgaatcta gattaggttg tatcataaat
    16141 tcttcataac ctggctttgt tggatacaaa ccgataaaat agcgtcctaa aagatagatt
    16201 gggcttgctc cccatgcatg gcataagctt tttccataag gatctccata catactgtac
    16261 ttttcatttc ctgtttgagt agggtcgtat tcttcccaga aagttaccgc atcatgagat
    16321 aacatccctc cccaataatc aagaatcgtt tggtagacga tattcgtctg tccgagtttg
    16381 cataaagcat cttgttcata gaatttgaaa tatggagtag taatctgtgt gatagtgtca
    16441 ttcaataaga cattctttaa gatcgattgc tgttggtctt tgttagcaaa atcgaataaa
    16501 acagcgaaaa tattcgcatg acgcgtcaca tttcttctcc cagattcata gcaatcgata
    16561 aaagcgccaa gttcttcatc ccaaaagtag tcaaataggt tttgtttcaa tagttgatat
    16621 ttttcttgat agagatgagt atgataattt tcgttctctc catatgtttc agctaagata
    16681 tctccgcaag tgatcatgga atgataggct ttcagtaata agacttgttc tgcagcaagc
    16741 gttccttctt tatccatttc agaccaatca ataaatatcc aatcttttgc tctcccataa
    16801 ataaacccta attcattcgt ttgctccatc aagtatctca ttaatgattg catcttaggg
    16861 tagacgatgc gtaaaaattc atagtctttc gtcatcatat agtggttttc gataccaatc
    16921 aaccacaaga tcgaatagtc aacgatagta ttcatatgct gcttgatttc attttgtcct
    16981 cttaatgcta atatcgttcg tttattgatt tcctcgtcaa aaaaaagata ttgattgatc
    17041 atgaatgatt gatacgcatc tccagaccaa atccagcgat ctcgtttgat accgtcgata
    17101 aaaaacaaat cactacataa cttgaaggct tcttctgata ctgaccagat ctgattcagt
    17161 aaagaagaat cgcttgaaaa agcagcttgt ttcgaaagag ataaaaattc atgaaaaact
    17221 tgaagttgaa ccattccagt agaaacctct ggtataaaca aatagcgaaa agcgcgttta
    17281 cgagctttca tttttcttgt cattcctatt tgcttatagt agcaataatc gatatccata
    17341 gcttctacat cggactctcc ataacataga gtgatagatt cgatatggtc atccagagat
    17401 attagttcta cacagccatt cactgctcgc ccaaaatcga ataagattcc tccgccaatc
    17461 tccgtttcag tgactggatg gacgcattct ttttgataat agatttgatt tggatctttt
    17521 gcgatatcga cataaagcgg actccagcca gctggatatt cttcaataaa attacttgct
    17581 gtccagccaa tatctgattt tacttcgtct ccctcgataa acatcgctgg tagccctgat
    17641 gtatgtccta caaagatacg aatttttgct ttaccagctg gacaagtcag ccattttcca
    17701 catggatgtt tttgtccatt aatttctaca tacccaactc cttggatcgt cactttaaac
    17761 atggaaggtt gatcaagaaa gtaatatctc ttaaacttga cgttccgatg gcaatcatcc
    17821 atgtaccagt acgctggcca gtcaaaacct cgttcttccc gttggaaatt ttgtagcagt
    17881 ccatggcgga tctcaaagtc tccaggatac caaagccatc tatctttatg tttttcattt
    17941 gtcattttac acgacctcca tcaaatttat tttgttgtca attgttcttt tatttcttca
    18001 tctactctta tcactgtctt tctattcgtc ctgtgtacta ctagaaggct aataagcgcg
    18061 ctaatcaaca gcaagatact gccattgacg aaaacagcaa gtgttttact cccaagagaa
    18121 gcaaaagaga gaaagagcaa accatatggt gcaatgaaag tacctaaatt agcgccaacc
    18181 aataagattg aagtattgaa actctccgcg tacttgggcg cttggatact tacttggttg
    18241 aataagtaag gaatgaataa cgaaaaagaa attcctgtta ggatcgcacc aaacccaatc
    18301 acatacaggt ttatcacagt ggcaatcaat acaaagccga ttcccatcag tagtaaagaa
    18361 agtgtaagca tatagcgatg tgcttttgtc tgaagccagc caaaacaaac tccggcagcc
    18421 atacttgcca attgcatgat tgttaagata ttcgctgcat tagtttcgtt tcctagagaa
    18481 taagtcgtca ggactgtggc taatttaatc gatacagcat tatataccac gatgaccagc
    18541 aagagaaaaa taccataact aatcatttta ggattcgttt tgattacttg tcttgttggg
    18601 gctgtgccat gcgattgaag ttcagttgtt tcaggtgtag gaacaaacaa aacaaacaag
    18661 acaagaatag gtaagctgat ggcgtagact aaaaaggtat attgccaacc gaactgtact
    18721 agctgtcctg caacaaatgt cattaaagct gcaccaaatc cttgaaatgc actttgaaaa
    18781 ccaatcatag aggctcgttc atctccgtga taaaaggcag caatcatgct gactgccaaa
    18841 gaattgatca atccaaagcc aatacctagt ccagctcttg aagctaagac aatactgtaa
    18901 ctttgtgaga agagggggag gataccacaa atcgatgcaa tcactaatcc gatgatcaca
    18961 gtttgttttt gtccgatttt cctagcaata aaactactaa tcaaaacaaa aatagtgacc
    19021 ataaaagagg gagcagtcgt taataattca acagcagata aagaacgcgt ggcataagta
    19081 gctgacatac tgggaattgc agacgtgact gcaccagcag aagtcaaaat aagagagact
    19141 gacagcagag aaaatttcat catcttttta ttcataagca tgttcctttc atttttgtaa
    19201 gcgcttatca aaaatatagt atgaagtggt tattctctca atagcggaat cacaggaagt
    19261 tcatgtccca accatagaaa gtctttatga aaccaaaaat agctttgcat ataatagcag
    19321 tacagcgtga actaataagc gaaagaaacc gcttacaaaa aggagggagt caattggaac
    19381 tagctgaatt agacattttt tttgcgtaac gaagaatcaa tcgaaactct gcagcgtgaa
    19441 caaggaatga atatcaatga tttaaactta gcttaccatc ttcagacacc gccaaaaatc
    19501 caccgagggg atctatttca acagggaaat attcatatca gtaaacaccg tcgatatgcg
    19561 gaagttcccg agcatacaca tgattttgtt gaaatcaatt atatgtatag cggtacatgt
    19621 ttacaaatta ttaatggaga aaggatagag atggaagaaa gtgacgtggt gatcattgat
    19681 aaagaagcta ctcaaagaat cgaatacaca gggcaagagg atattttaat caacatctta
    19741 ttaaaagaag aaaccttatc tacagagata ttgaatcatt tggcaagcac aaataatcta
    19801 ctttcttctt ttttgataaa tgcatcaaaa gaaaaagggg aacatacaca attcattcat
    19861 tttcgcggcg gaaaaacaag tcgtttgacg catttgattg aaaatatgct gttgatttat
    19921 tttgatacat acagtcataa gatccgttcg ttaaatctct atacatcact attactgatc
    19981 gaattgactc atttattaga acaacaaagc ttttcatcag cagatggatg cgcagaaaat
    20041 gagatgctta gagtattaga ttatatcgat aagcatttta cttcttgtac gttaaaagaa
    20101 acagcagctc attttggcta caatccggtc tatcttagta ataaattgaa aatgtatttt
    20161 gatgcttcct ttcaagaact ggttctaaag aaaaaattcg actttgcgtt ggaactgatt
    20221 caagaaacga gtttttcgtt ggaagaaatc gctaatcgta tcggatataa acaaacgact
    20281 tctttattca aattattcaa gaagtattca acatgtactc ccaatgaatg gagaaataaa
    20341 cattaagaag aaaatctttc actaaagcat atgaaggaaa attgttttag gtgcgattgc
    20401 tgtcttatta tatcgttgca gcgaattttt ttggatttat tttcagttct aaacttttgg
    20461 ttgtattatc aggggatata ggtgtaaaca tttgtcattt atctgttatg cgtattcagg
    20521 aattcgtttc catcaaaaat tataataaca actattataa ttaacatgtt gataaaatga
    20581 ataaacaaga ctatactttt catgaaagta acaaatagtt atgaaaagga gctgtttatt
    20641 catgaaaaaa acaagtcgta aagtagtaat cgtcggtaca ggttttgttg gaacaagtat
    20701 cgcttatgca atgatcaacc aaggaatctc taatgaatta gtattgatcg atgtgaatca
    20761 agaaaaagca gaaggggaag cattggacct tttagatggt atggcttggg gcgatgaaaa
    20821 tgtggctgta tggtcaggtg gctatgaaga atgtaaagat gctgatatcg ttgttatcac
    20881 agctggtatc aaccaaaaac ctggtcaatc tcgtttagat ttagttaaaa caaatgcgtc
    20941 aatcatgcgc caaatcgtaa aagaaatcat gggatcagga ttcgacggta ttatcgttgt
    21001 tgcttcaaac ccagtagata ttttgacata tatcgcttgg aacgaatctg gtctgccaac
    21061 atcacgtgtt atcggtactg gaacaacatt ggatacaact cgtttccgta aagaaatcgc
    21121 attgaaatta aaagttgacc cacgcagcgt ccacggctat atcttaggtg aacatggtga
    21181 ttcagaagtt gctgcatggt cacatacaac tgtcggtggt aaaccagtgt ttgaaattgt
    21241 agaaaaagac catcgtattg cccaagatga attagatgtg attgctgata aagtccgtaa
    21301 tgctgcttat gagatcattg atcgtaaaaa agcaacttac tatggtattg gtatgagtac
    21361 tgcacgtatc gtaaaagcta tcttgaataa cgaacaagct gtattgcctg tatctgctta
    21421 tttaactggt gaatacgacg aaaaagatat ctttacaggt gtgccatcaa tcgttgacga
    21481 aaatggtgtt cgtgaagttg ttgaattatc aatcaacgaa gaagaaaaag caatgttcag
    21541 caaatcaaca agtgctttaa gagaagtatt gaacactgta ttataagaaa caatgaatat
    21601 gaactaaaaa tcctaaaact gcttaacagc tgaaatagct gttaagcagt tttttattga
    21661 tatctaatag gtaagcaaat aaacagaatg gttaaaatta atcggtccga aaatgtatcc
    21721 gtacatatga acatatgaaa tttaatctgt tgattacaat aagcgaatcg ttatcaatgt
    21781 ttatctgtgg ttaattaaaa aatccttccg caacggcaaa tacaatgatt catatctaat
    21841 tcgttcatat ttgattaact gaataaagaa actggttttt atcattcaat taaacgacaa
    21901 aaaaagtaag aaaaactgca aaattttttt ataattttgc ataagcagat tttgatggaa
    21961 aaatgacgat ttttgataaa aaaccgttcg agagaggttt atcattttt
//
LOCUS       DAZKCW010000043        21955 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000043 DAZKCW010000000
VERSION     DAZKCW010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.043"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(40..483)
                     /locus_tag="ACG84Z_001896"
     CDS             complement(40..483)
                     /locus_tag="ACG84Z_001896"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9162709.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(499..1659)
                     /locus_tag="ACG84Z_001897"
     CDS             complement(499..1659)
                     /locus_tag="ACG84Z_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFP9162710.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            2166..3866
                     /locus_tag="ACG84Z_001898"
     CDS             2166..3866
                     /locus_tag="ACG84Z_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162711.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(3968..4801)
                     /locus_tag="ACG84Z_001899"
     CDS             complement(3968..4801)
                     /locus_tag="ACG84Z_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFP9162712.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(5105..7270)
                     /locus_tag="ACG84Z_001900"
     CDS             complement(5105..7270)
                     /locus_tag="ACG84Z_001900"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFP9162713.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKNPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7530..9824
                     /locus_tag="ACG84Z_001901"
     CDS             7530..9824
                     /locus_tag="ACG84Z_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFP9162714.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            9817..10482
                     /gene="pgmB"
                     /locus_tag="ACG84Z_001902"
     CDS             9817..10482
                     /gene="pgmB"
                     /locus_tag="ACG84Z_001902"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFP9162715.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            10475..11482
                     /locus_tag="ACG84Z_001903"
     CDS             10475..11482
                     /locus_tag="ACG84Z_001903"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFP9162716.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            11504..12523
                     /locus_tag="ACG84Z_001904"
     CDS             11504..12523
                     /locus_tag="ACG84Z_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9162717.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(12804..14171)
                     /gene="nhaC"
                     /locus_tag="ACG84Z_001905"
     CDS             complement(12804..14171)
                     /gene="nhaC"
                     /locus_tag="ACG84Z_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFP9162718.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(14280..15701)
                     /gene="tyrP"
                     /locus_tag="ACG84Z_001906"
     CDS             complement(14280..15701)
                     /gene="tyrP"
                     /locus_tag="ACG84Z_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFP9162719.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(15944..17821)
                     /gene="tdc"
                     /locus_tag="ACG84Z_001907"
     CDS             complement(15944..17821)
                     /gene="tdc"
                     /locus_tag="ACG84Z_001907"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFP9162720.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRNVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(18112..19368)
                     /gene="tyrS"
                     /locus_tag="ACG84Z_001908"
     CDS             complement(18112..19368)
                     /gene="tyrS"
                     /locus_tag="ACG84Z_001908"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFP9162721.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(19480..19685)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            19948..21249
                     /locus_tag="ACG84Z_001909"
     CDS             19948..21249
                     /locus_tag="ACG84Z_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFP9162722.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(21318..21917)
                     /locus_tag="ACG84Z_001910"
     CDS             complement(21318..21917)
                     /locus_tag="ACG84Z_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9162723.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT         6618 a         4589 c         3922 g         6826 t
ORIGIN      
        1 aaaaattagg ctgggagcat tatttcgtta ttctgttcat caaaaatcag cgttttgatt
       61 ccatttcatc acaagttcct cctcatttac tgcttcatct ttttgctgtg tttgaattgt
      121 aaaaccttgt gaaagataga aatgaatagc tgattgattt ttttgataga ctgtcaaagt
      181 cagtgtttta ttggtttctt ttattttttt cattagttgc gtaccgattc tttgttgccg
      241 gtattccctt ttcacaaaga ttcctgcgat aaactgatca atcaccccag caaaaccaat
      301 aatttcttga tctatttctg ctaagtaaat cactgcatct ggtaaagctt tcctaacaga
      361 ttctacttga ttctcccaat aagttgatgg aatgaattca tgagaatcca agttagcatg
      421 cagccaaatc gatagaacag attccagttc tttggcagac aattttgttg ttgtgcggat
      481 cattttttct ctccttactt attcattgat tttaaaataa aaaccatttt tttgaagctc
      541 ttttacaagt tttcgcccct caaaaaagta tatcttctct tgttttactt ttctaatacc
      601 aaaagaaaca gcaactttag gatcatcagc tgaaacgatt cgataagttc caccaggcaa
      661 ttgatccagc ttgactttcc catgatggtc gctttgtact gaaaacggca caccatttct
      721 agtaagtgtt tttttcttat gtttcaaaat gaatgaacta ccatttaccg gtttccctga
      781 cgaatcacta ataataaatg aaaaatcaag cactttttta cttaatctat actgatagat
      841 tagtcgtccg ataaacacta acagtatgac tacagctatt atcgttcctg caagaataaa
      901 ccattgccgc atggttcttt cctgatttcc ttttccttct tcttttttta ccgattcgtt
      961 ataaggaatc cgatgtcctg tcactagcaa acgatgcgtg ttgatcatat acggcgtaca
     1021 tgtaagcaag gtaactaagt cttctccttc tgaaatcgtt agaacagacg tgtcatctgg
     1081 cagtaccact tgtatatttt taacttgata agccaatttc tcccccaaaa cagtcaaaat
     1141 aaacgtgtct ccgttttcta aacgatctaa ttcggtaaat aaccgtcgat taggtaaacc
     1201 gctgtgagca gagatcactg aatgcgtcga atttccacca agcgggaaag aggttccttg
     1261 caagacgcct gctccatttt caaggatcct accattgagc cgatcataaa gtgaaatatt
     1321 taattggatc ttaggtatat tgatacttcc gatcagccat tcctctaatt ggctggatgt
     1381 tgtactttca tttctgttct tttcattgaa aggatcagta ccaggattga atccttggtc
     1441 agttaatcgt tggtttttct cctccatttt ctttcgctgc acttcaattt cagctgcggt
     1501 ccgtttttgt acttgttcga tacgtttttg atcaataaaa ctatttaaag aatccacata
     1561 aaatggatat aaagcgatca gtaaccctac gacgatacat attaataaaa acaaacgaaa
     1621 caaaagtcga cgagactgtt tttgcttact ctgcttcaca tgtgtcctcc cttgcaagtt
     1681 tttttgttct ttcttttatt atatgggttc aggaaaaaaa tagaaaatga aagccgatga
     1741 ggttgtgaaa aagctgtcct gcatcaagta ataagtacag cccaaaaaaa tagctactca
     1801 tattttttgt tgggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaagga
     1861 agaggttgtg aaaactgcgt tatgctttga gtaataagag cgctagtcag aaaatagctt
     1921 ctcatatttt ctaggctagt gagcttatta ccgagaagca gctgattgaa caccgtttac
     1981 cgagaggtca tgaaaaagct actttgtttc gagtattaag aaaaattctg tttcaaaaca
     2041 aggagatgca acaaaactta tgtcgcatcc tctctcctta gaactttcac ttatgttttt
     2101 cttgtaaaat tcataaatat tttcatgaat tttctaattt cttgcctacc tctcgcatag
     2161 gatatatgat gaatttatct aaagtttgca aaggagttcg acaattgaaa aaatatggcc
     2221 catttttagc aatttttttc attgctttgg catttctcat gcctcattta ttcacacata
     2281 aactaatttt gggtgctgat gccccattcc attacaatcg gttctatgat gccgcgcaac
     2341 aaattaaata tggggatttc cattattttc cttcccttta tggattccag caaagtggca
     2401 ggatcgtgaa tgccgtttac ggcccatttt tcgcttattt acaaggattg atcgtgttgc
     2461 ttgcaggtag ctggtttcat tatcagattc tttcaaattt cattctttat cttatttcag
     2521 gattttctat gctgatttta ctgagatatg tcaatgttcg aaattgggta agtgtaccag
     2581 tagccgtttt attcatgagt acgtattcta ttcaatactg gtctatcaac caaggattca
     2641 ctagctgggg gacttgtttt tatcctttat gtatgatccc tattgctgat ttcgtccttc
     2701 ataaaaagtt ccctgttatc aaagtcgctg tctcagtggg acttatgaca cagatccatt
     2761 tactgtcttc gatcatgtta gctttgatgt atatcccttt ttatctttat tactttttta
     2821 accagactga aaaaggaaaa gcactgcttc aactgattaa gtcggtcttg ctttattttg
     2881 ttctgacagc aaatatttgg gcaggattag ctattgttta cagtgggaat aagattcttc
     2941 ctccctttgt taacagagaa atgagtcaaa aggcgataga tctggatggc agttattggc
     3001 tccattaccc taaggccttt cctatattga tattatcagg ttttttgctt tttattttct
     3061 ttcaacaaaa gaacacctta ttccaaaaaa tcgtgttgta cacaagtctt gttttctttt
     3121 ttctttctac tagcttgatt ccatggacga cattgatcga aaaaaatgtg ccttttatta
     3181 gtttgatcca gtttccattt cgatttttcg tgccatttac gctattgctt ctactttacc
     3241 ttgccctttc actgaaccag tggtctgaac aaaagtggtt ccgtctttta agtatatttg
     3301 gcattcttat tttttcagca cagacgatcc agaacttata ccagcatctg gaaaagtggg
     3361 aaaatgaaac atttgtcagt cgacatactt atctattcga tacgccggaa gaagcaagga
     3421 aaacattctt cagcaaagat atgtctacca gcttgttcgt tttccaaaaa accacacctg
     3481 actatctgcc aatctataag gagacaaaag acaataaata cgaccggtat aacgaagaaa
     3541 tactagaaaa cgaaacaact tttataaaaa cacatccagg cggtcttttg acaatcaagt
     3601 ggaaaaacac tggggacaaa actgttcata tccctgttat cgtctacgat cggactgtgc
     3661 tacagcaaaa tggaaaaaca ttgactgatt atgaagtaac agatatcggg accccaatcg
     3721 tgaagcagca aaaaggaatc aacgagctca cgcttcatta tcaaacgcca atctatttct
     3781 atttcattct ttctcttact ttgattggct ggtttacctt gctatgttta tttatttatc
     3841 atagatacaa gcttttacgt gcttaggcaa aagggataaa tacatccgat caaaaaactc
     3901 tccaaacggt ataatcgttt ggagagtttt attttaatca gtttttttat gttatatgtt
     3961 atatttttta ttcgttcaca tctaattcga tttccacccc gtagtgatca ctgatgattg
     4021 gactatcgat cccatcaaaa atccgttgat attttttaac ctgcattcct tcagggacga
     4081 aaataaaatc tatacgcaat ttttctgtat tttgttccca accatctatt ttcttttcca
     4141 cagtagctgc ttttcctttt tcattcgcga caacatacga atcttgaaga agaaggcaac
     4201 tttctcttac agtataataa ccttgagagt ctactggatt attgaaatca cctaggaaaa
     4261 aaagtggtac gcgagtttcc aaaaagtagt tttccaagtt tttccactca aaataaaagc
     4321 cacttttttt atctgtccac caagaaaagt ggcagctcga gacaaaaatg tcctgatcat
     4381 ctatctttgt tttcccaatc aagatcttgc gtgtctgata atcttctttc ttttgaaatt
     4441 gggagacggt aaggacctga ctttccaatg tttttttcgt aagcagtgca tttccttctt
     4501 catatttatc ataaccgatg tggctcattt cccaactcca aaaatactct tttccgtgtt
     4561 cctttaaaag ctgaactaaa cggtaggcaa aattatcttt acggataggt acttgattct
     4621 ttaccggaca gaacttcatt agcttcgcag gttctacttc ttcagattcc agtaattggt
     4681 tgatttcttg taaagcaatc acttcataat cttctaacag gatcttatct gctaattctt
     4741 gcaatttttt ctctggttct ggctcaagcc agctatgcgt gttgagtgtc atgaatttca
     4801 ttggttttct ccttgtcttc atttcgaaac aaaagggttg tgacaaaatt tttgtcacaa
     4861 cctctccagc aaatagtgtt ctcctgctaa ctcctcagta ataagctcaa tggaccagga
     4921 gctatttttt gtttggctgt ttttatcact tggtgcaggg cagctttttc acgacctctc
     4981 cactaaacag tattcaaact gctgcttctc ggtaataagc ccaaccaaac gaaaaatagg
     5041 aggagctatt tttgtttggc tgttcttatg acttgatgca ggacagcttt ttcacaacct
     5101 ctccttacat tttaatggag ccgatcactt taccagctgt cactgtacct aattgcttga
     5161 tcactacttc ttctacttta tcgtttgtaa atacgatcat gatcgttgga tctttttctt
     5221 cgttttggat cacatcaaga tccatctcag ctaatttcgt tcctgttcct acttcttggc
     5281 cttctttgac agcaatctca aaagctggct gattcatttg gactgtatcg attcccatat
     5341 ggatcaaaac ttcgatacca tctttcgttt ccagcccaat tgcatgtttg ctagggaaaa
     5401 tacttgtcac ttttccagcg atcggcgcaa caacttctct tgatgttgga ataacagcaa
     5461 agccgtcacc catcattttt tgtgagaata ccggattttt tacttcagat aaaggaatca
     5521 cttctccaga agctgcggaa actagttctt gttctatacc taagtattgc ttactacctg
     5581 cttgtccatt tcctgtagaa accatttctg gctctggaat ctctgctcct gattgcagca
     5641 gatcttcgat atctgatttc aagacatctg cttttggtcc ataaactgct tggactccat
     5701 tgtctttgac gatcaatccc atcgcccctg ctcgtttcca ggcttcttca gtccctactt
     5761 tttctcgatc atttacactt acgcgtaacc gagtcataca agcatcgaca tctttgatat
     5821 tttcttttcc tcccagcaaa tgaatgatct ggaccacttg ctgatctgct gttcctgttc
     5881 cgctgttaga tacaacggtt tcttcactgt cattgtcgta atttccgtta cgtcccggtg
     5941 tagcaaagtt gaattttttg atcaagaaat ttgctaagaa atacgtaaca acaccaaaag
     6001 cgatcacaca caacacgaag ttgataagat ctccacctag acccgctttg atagctaacg
     6061 gtgtccgagt cagcaattcg atattcccaa atgaatggac ccgcaatggc aagatatctg
     6121 ccatcgcaaa tgcagcccct tggatcactg aataaatgac atataatggc acagcagcaa
     6181 acataaacat gaactccaat ggttctgtta cacctgttag aaagacagcc aacgctgctg
     6241 aaaaatacat tgatttatat cttgctttct tatcaggatc gacattacga tacatcgcaa
     6301 aagccattcc catcaagata cctgaagaac caatcatttg tcctactttg aaacgagccg
     6361 gcgtccagtt atgcaacaca aactcatatt gcgacatatc ccctgcacct ttaagattca
     6421 ctaaatcagt ggcccaagcc aaccataacg gatcttgccc aaatacttgt gtccccgcct
     6481 gtgcgcctga taaaatctca tacgatccgc caagctgtgt atagttgata ggaatcgtca
     6541 gcatatgatg caatccaaat ggcaatagta aacgttctaa tgttccaaat aaaaacggtg
     6601 ctagaatcgg tgcgctttct tgtgattctg caatccataa accaaaatta ttgattccag
     6661 cctgtacgtt tggccacacc acagcaagaa tcaatgccac gattgttgac cataagataa
     6721 caacaaacgg aacaaagcgc tttccattga aaaatgacaa agcatccggc aattttctat
     6781 aattatagta cttattataa gccattgccc cgacaaatcc agcgatgatc cctacgaata
     6841 ctcccatatt caaagctggt gcttccaata cacttgtaaa aaatccttta accatgatct
     6901 tcgtaccgaa cagagtgtgg gtaaatgcat cttcattcgc aagcatgtca cttgtgacac
     6961 caaagatagc cccagtgatc cgattgatta aaataaatga gatcccagct gcaaatgctc
     7021 cgcctgctct ttcttttgcc caacttcctc ctattgctaa agcaaataaa atatgaagat
     7081 taccaataat tgcccaacca atattttcaa ttactccgcc cgttgtgaca agcggcgtcc
     7141 aatcaggatt gatcaaggga attgatttcc ctatactgat catcaaccca gctgccggca
     7201 taactgctac cacaaccatt aaagcctttc caaatttttg ccaaaactca aaactaaata
     7261 tctttttcat tccgtttagc tcctttacgc aatcggtttc gttaaacgta ttatagcgtg
     7321 cgttttcttt tttgtaaatg ctttattttt tatttttctg tctataccat tctataaaac
     7381 ctataatacg tgtgttccct tctataattt tctcctaaaa atttattttt ttaagctttt
     7441 ttctatgaaa tattttcttt tgtctattga cttgtgcaat cggttgcgtt tattatgaac
     7501 gtataaaaca gctcattagg aggagaaaaa tgaaacagat caaacgacta tttgctattg
     7561 atccatggaa aatcagcacg acacaattag ataaaaaaaa tcttcgactg caagaatctt
     7621 taacaagtat tggaaacggt tatatgggga tgcgcgggaa ctttgaagaa acttactcag
     7681 gggaccacca tcaaggtact tatttggcgg gtgtctggta tcccgataag acacgtgtcg
     7741 gctggtggaa aaatggttat ccagaatact ttggaaaagt gatcaacgcc ttgaacttta
     7801 tcgcgataga tatttcgatc aacgatcagc tgatcgactt ggcttctttg gaaccagaag
     7861 acttttactg ggaattagat atgaaaaatg gtgtattatc tcgtacattc acaatcacta
     7921 cttctactaa taaagtacgc atttccttcg aacgttttct gagcattgtc aaaaaagaat
     7981 cagcttatat ctatttaact atagaaatgc ttgaaggtag cggaacagtc aaactcgtat
     8041 caaaattgga tggaaatgtt caaaacgaag acagcaacta tgatgaacat ttttggaatg
     8101 agattgatcg tggaactata gaagaaatcg gctatttgac gactaaaact attccaaaca
     8161 actttgggat tgaacaattt actgttactg cagcaatgcg ccatttcgtt aatggaaaat
     8221 cagtcatccc tgactatcac gaagatactt tagcattaca tggttgcttg tctgcagaat
     8281 tatctcaagg tgagacatgg tcagtggaaa aagaaattat cgttcttact agtagagata
     8341 ttccagaagc gcagcaagca gaaaaagctg tctcagaatt aacgaaccag acaaacaatt
     8401 atatccaagc aaaagaagag caaacagcgg cttgggcaga acgatggaag cttgccgatg
     8461 tggtcatcga aggagacgaa gaagcacaac aaggtattcg attcaatttg ttccaactat
     8521 tctctactta ctacggcgaa gatgaacgat tgaatatcgg ccccaaagga ttcacaggag
     8581 aaaaatacgg cggagccact tactgggata cagaagcgta tgctgtccct ctttatcttg
     8641 ctttagccaa acctgaagta actaagaatc tgctgaaata tcggcataat caactgccgc
     8701 aagcaatcca caacgctcag caacaaggat taaaaggcgc gctttatcct atggtcacct
     8761 tcactggtgt cgaatgccat aacgagtggg aaatcacatt cgaggagatt caccgaaatg
     8821 gcgcgattgc ctatgcaatc tacaattata cgaattacac cggcgatacg gaatatttga
     8881 aaaatgaagg actggaagtt ttagcagaaa tcgcacgctt ctgggcagac cgtgtccatt
     8941 tttcaaaacg agcaaataaa tacatgatcc acggtgtgac cggcccaaac gaatatgaga
     9001 acaatatcaa taacaattgg tatacaaata cgatcgcagc ttgggtcttg cgttacacgc
     9061 gagaaaatta tttaacttat caaaaagaag ctgctatcac tatcagcgaa gaagaactag
     9121 ccaaatggaa agatatcgca gagaacatgt acttcccagt tgacgaagaa ttaggaatct
     9181 ttgtccagca tgacacattc ttagataaag atctcatgcc tgtatccgat attcccacaa
     9241 gcgatcttcc tctgaatcag cattggtctt gggacaaaat ccttagatct tgcttcatca
     9301 agcaggcaga tgtactacag gggatttatt tcttcaatga tacttttaca aaagaagaaa
     9361 agcaaaaaaa ctttgatttc tatgaaccaa tgactgtcca tgagtcttcc ctttcgccaa
     9421 gtatccattc gattttagca gcagaattag gaatggaaag caaagctgta gaaatgtacc
     9481 agcgaacagc tcgcttggat ttggataatt acaataacga cacagaagac ggcttgcaca
     9541 tcacttccat gactggtagc tggttgtcga ttgtccaagg atttgctcaa atgaaaactg
     9601 cccatgatca gttgagattc gcaccatttc tgccaaaaac ttggaaagct tattctttcc
     9661 atatcaatta tcgcggacgt ttattgttca tctcagtcac agatgaacaa gttactttcg
     9721 agttattaga aggttctcct ctagaaattt acgtctatga acagtcttat tctttagcgg
     9781 atcgtctaga aataacgcta agaaaggagg aagcaaatgt ttaaaggggt attgtttgat
     9841 ttagacggtg tcattaccga tactgctgaa ttccattatc gtgcttggcg aaagcttggt
     9901 caggaaatcg gcattacgat cgaccacaca ttcaacgaac agctaaaagg cgtcagccga
     9961 gaagactcac tctctttgct tttagcttat ggcggaaaag aacactcttt ttcaaaggaa
    10021 gaatttgcag aattagcgaa aagaaaaaac gattattatt tagagatgat ccagacgatc
    10081 gaaccaaaag atgtcttccc cggggtcgtg cctttactgg attctttaaa agaagaaaaa
    10141 atcaagattg ctcttgcttc tgcaagtaaa aacgggccat tcctacttga aaaaatgggt
    10201 cttacacctt actttgatgc tattgccgac ccggcagaag caacaaacgg aaaacctgcg
    10261 ccagatatct tcctccttgc agcaaaagct gtcggactaa aagcagaaga atgtatcggg
    10321 atcgaagacg cgcaagccgg tatccaagcc atcctctcaa gtggcgctca accaattggc
    10381 gtgggacgtg ctgaagacct tggagaggag atcccgcttg tccctgatac gacttttctt
    10441 acgatcgatt acttgaaaga aaagtggcat gaccatggat aatccagaga tctccgtcgt
    10501 accagttcca gagactgaaa taaagaaaat cacattgaag aacgactact tagaagtcgt
    10561 tcttctcaat tacggtgccc gcctgcacca aatcttcgca ccagacaaag aaggaaaatc
    10621 agaaaatgtt ttattgtctt acgatcgttt cgaagatgtt ctaacagaca aaagcttttt
    10681 tggagcaact gtcggacctg tagccggaag gatccgggat gcttcttggg gtgagcatag
    10741 attggagaaa aactgcggat cacaccatat ccacggtggc acgaaaggct ggtctttcca
    10801 attttgggaa gtagaagttt tcaaaactcc atcatcaata ggtgtggtct tttacttaaa
    10861 agatgaattt tctacctatc caggaccaat cactgctacg atcacttacc gtttaacaaa
    10921 aaacgaatta gagatgacaa cctctgctag tagccttgtt gaaaccatct gcaatccgac
    10981 caaccatgcc tacttcaacc tttcaggaaa tggaacaaga gacatctatg aacatcagtt
    11041 aacggtcttt ttagatggtg tgcttgaatt agatcaagaa aaactgccta ctggaaattg
    11101 gacaaaaaaa gaaaaactgc caatcgactt tagaaaatcc ccaacactgc aagagatcct
    11161 tgcatgttat ccagatggac tagatgatgt atttcttttg catcatccta ggctttccaa
    11221 aacttcctta caattattcg agaagcattc tggtcgccaa atgactatag caacttctaa
    11281 taaaagtatg gtattatttt ctacgactgg attcgaagct gatttctctg tcaatggaaa
    11341 acagatgcat tcaaactacg gattagcaat cgaaccgcaa gaaatccctg atatcgttca
    11401 tttccccaaa tttggatcga tcaacctcca tcctggtcaa gaacggatca gtcagacgat
    11461 ttatcggttc tctgcacaat aacaagagaa aggtgttttt atcatggcta ttaccgtaaa
    11521 agatgtggcg aaaaaagccg gtgttgccac ctcgaccgtc tctcgtgtca tcaacgatca
    11581 tcctagtatt tccgagacaa caaagaagaa agtccgaaaa attatggatg aactaggtta
    11641 tgttcctaac atgactgccc gcaatctagg aaaacgcatt tccagtgcca tcggcgtaat
    11701 cttaccccct cttgattcaa aagagcggat cggtaaccca ttttatcttg agatcatgga
    11761 agcaatcaac gaagaagcgc ggaattatga tatgactaca gcaatcgcta ctgctaaaaa
    11821 ttttgaattg ctgttagaga acgtccagcg tatgcattta caaaaacaag tagatggttt
    11881 tattctagtg tattcagata gtcaagatac tgtcattgat tatttatacc aaaaccacat
    11941 ccctttcact ttgatcggac agccttatca tcatgagaac gaaatcgttt atgtagataa
    12001 tgataaccag cttctaggta aacaagcaac agaatttttg atccagaatg gacataagaa
    12061 tatcctgttt gtgacaaaca cgactcatga aagtttgtat ttcgaacgat atttcggtta
    12121 tcaaaaagca atgatgatgg ctggtcttcc tgcgttatcc agtgtagtac tagagcatcc
    12181 ggaggattat ctgtcctttg agaaaacgtt gaaagaaaac gaagccacag cattggtggt
    12241 cattgacgat atcttcgccc ttcgcacgat gcagttggcg caaatgtatg gctatgtcat
    12301 tccagagaca ctctccgtca ttagcttcaa caactcgatc ttctcaacat taacacaccc
    12361 ttaccttaca agtatcgata tcgatatctc cgaattagga cgtgtcgcta tgcaaaagct
    12421 gcgcgaattg atccatgaag aattgagcag tggcgtacgt ttggtcatcc ctcatcgctt
    12481 gatcaaaaga gagacagtcg ttcctttaga aaacccatac taaatagctg actcactaaa
    12541 tacgctgacc atttatccta tggtcagctt tttatgtaaa agaagatact acttctaaca
    12601 cattgtttat ctgtaaaaaa gagcgtggga caaaagtaaa gaacactttt gtctcacgct
    12661 ctaaacacgt ataaacggcg gaagcagaag caactccttc ggaaataagc tgaaattcac
    12721 aaaaatttaa aaagcaattt tcttgagttt cttcttattt cttggagtta aacgcttctg
    12781 tcccagcctc ttttttcctt ccttcaattt tttacacgtc gacgattcaa taaaaaaccg
    12841 cctaatattg taaagacagg tgcaagaatc gagaaaaagg cgaatggcaa gtaatgcaac
    12901 gcgctaactt tcatcgttcc cataatgaat gtgccgctga ctccccacgg tacgagagaa
    12961 ttgacggtcg cacctgaatc cgctagtgtt cgtgtcaaat aggtttttga taagccaacg
    13021 tcatcaaaag aacgcttgaa tgtttctcct ggaagaatga tggacagata ctgttctcca
    13081 acgatcagat tgattccgat acagctcaag gcagtaaacc cgactaaacg agaaggtcgg
    13141 tccatctttt cttttaattc ttgaacgatg gtatcaacga tcagatattt gatcagtaac
    13201 ccacctaatg ccaatgcaag taaaatcaaa ctagcagaac ctaacatact catgatcccg
    13261 cctcgagaaa gcagttcatc tagctttgga tcaggtgtat ttgcgacata accattcatc
    13321 aagatgtctg ctgcttttcc gaccgtcaaa cttttctcat ggataaaaga aagaacgaga
    13381 gcagctgtcg atcccgctag taatgtaggg atagccggaa tttttttgat tgccccccca
    13441 aataaaataa ctagtggaat caatgtccaa ggagagatcc aaaagctcgc tttcatgttt
    13501 tggatcattt cattgatact agctagatcg gctgaatgac tgttatgtcc taatatcgta
    13561 taaaaaatca acgaaaggac gaatgctggg aaatccgtat aacgcatacc agcgatatgt
    13621 tcgaatagat taactcctcc aatacccgct gccaagttgg tcgtatctga taaaggcgag
    13681 cagttattcc ctaaaaaggc accggaaacg actgcgcctg tagtcattgc atcattgaat
    13741 ccaagtaaat gaccgatccc caaaaaagca attccaatcg tcgaaatcgt tgtaaatgaa
    13801 ctgccgacag tcactccgac aattgcacaa acaagaaatg ctgtcggtaa aaagaaacgc
    13861 acagaaacaa gtttaaatcc ataaaccata atcgtaggga tggttccaga taaaatccat
    13921 gaagcaacta agacaccaat caaaagaaaa atcaggattg gaatgatccc tggagtgatt
    13981 cctttgatga tcccgtcatg gatctcatcc catgtgaact ttttaaatct gccataaaac
    14041 aacaaacaca tgaaagctgc aaggatcggg atatgtggcg agagctggaa tccgatgatc
    14101 agtactccta ggagtgccaa caacacgatc aatacagcga tactttcttt taaagaaata
    14161 tttttattca tcgtcgatct cctatttcaa atgaaaaggc cctgccatga aaaaactatt
    14221 cacttggcag gacctcctac taaatcagcg acaaaacgtc ggctgaaaga cttatttttt
    14281 tatttttctt ctaaactttt ttctacctca atcccccaag aatctttctt gaagtgattg
    14341 atgatcaatg gaataacgaa catgaccact gtgatagctg ctactaataa tgcatcactc
    14401 aatgtcgctg tacctaatgt agcaaatacg acaacgatga tagagaagat cagcatgcag
    14461 ctgactaccc aagctaatcc gtttccgttt ttaccaattc ggtaaggacg ttcgaattct
    14521 ggatgtttct tacgcatttt aagcaatgaa acagcaatca aaatgtacac gatacaataa
    14581 ataacagttg tagcatttgt aagtgtcaag aatacagcac ttacgtcatc cattacacca
    14641 taaagcaaag caaataatga aataacgatt gattgtgtta gaacgacatt tctagatacg
    14701 ccgtatttgt tttctttatg gaatccgaat tttggtggaa ggaatccttc acgagctact
    14761 tggatgattg tttttgatgg tccagtaacc caagctgata attgtaaaag cacaccaata
    14821 aataccatga agctgaagat atttccgatc acttctggta agcctaggat ttgacagtca
    14881 atcaagatag gctgcgtgat atttgctaat tccatttttc catctggtac gacatttgct
    14941 acaagcatcg cattgatgac attcaataaa actaatccga tcaaagcgat aaatacgcct
    15001 tttgtataat tttttgttgc gtctttcaaa cgaggcatgt aaacagaact catttcgatc
    15061 ccaacaaaaa taaatgtgat accagctaag tatttcaatg aatcaatatg ttccaagtca
    15121 gggaaagctt ttgaccatga aaagtcacct agatagccgt ttgagactag tccgactttg
    15181 aaggctgcca aaacacctaa aacgaacatg atgactactg ggatatatac ccctagccat
    15241 acaccgatgt tcccgccgac ttttgccata tcgaatttca agttcaagat cgtgatgatc
    15301 cagtagataa ctaaaataca acctaaaacg aaccagtgat tattgccaag ttctacatta
    15361 ccaaatgtgt ttcctaacaa tggtcctaaa gtagaagcga ccattaccat acctgggaac
    15421 atttgcaccc ataatagcca tgcaacgaca aatccccatt tgctgcccag tgctgttttt
    15481 acccataact gaggaccgcc ttcttgagga agcatcgtgg aaagctcacc ggaaaccatt
    15541 gatatcggac cggcaaaaaa caaaactgca aaaattgaat aaaaaatcaa tgtccaaccg
    15601 actgcggcta acgtaggaat actccgaacc gttgcacaca gtgccattgt cagaccgata
    15661 aaggtcccaa gacccatttt acttacttca gatttactca ccgttgacac tctccttgat
    15721 tttttggata aaataacggt gtctttgaag tagtttcagc aataaacgaa acaattcagc
    15781 gaatatttga ggggattctt tgagtttatt gcttgaaggg tttcttcaaa gacaacctca
    15841 aaacaaaggg atcgaagagc ttaggtctcc ccttgctctt cagatccaaa catgcgtcag
    15901 aaacagttag tattcaagct gttttctaac atgattacct tgcttatttt gcttcgcttg
    15961 ccaataattg gtctgcgtag attttttcca atttttcttg aagagctgct ttgatttttt
    16021 cagcatattc ttcaaagtgt tcttctttgt tcatgtatgg tgtcattacg ctggcacgca
    16081 atacagttac ttttccggca cggttccatt cttcatctga gaatcctagt tggttcacaa
    16141 attgtaatgg gctgttgcca tagtctggga tagcaaagtc agtatgtgaa gttaagaact
    16201 cattaccgta aatgcttcct ttcacgtatg aagaataatc atatacgtca tggttcaatt
    16261 tattcattgc aactaagtca tcgttgcctt tttctttgaa tacatagtct accatattga
    16321 aatctggata agttaatgga tgaacttcga tttctttgtc tcctacttta aatgacaagt
    16381 cattcaagaa gttgtagaaa cgatgtgcac cttcgattga tgcacccatt aatttaccat
    16441 atcctgtgac attcaaaggt aagacatggt gtgctgccca aacgctggct gctgttgccc
    16501 ctgcttttga accttccaag atataagccc caagtaatgc tgggatatct gcgccttttt
    16561 caaatacata tgtcgcaaag taagagataa cgtttctcat gcggatatct ttgatgacga
    16621 taccaccggc agaatatgga acatagccca ttttatgtgg gtcaatcgtt acagattctg
    16681 cttcttcgat tgctttatat gcactgtgta cttcttctaa gatataatct ttgttttctg
    16741 taaagacatt gtatttgtaa tgaacatctt ttaaatcttc aaatggaatg aagttgttgt
    16801 cttcgtctaa gaaaatcgca cggccgtatc cgccataagc agcatctacg tgtaagtaga
    16861 agtaaatacc gtctttttct aatacgcgac gcaatgcaac gattttatcg ataccgtcga
    16921 ttgctccttc ttctgttgat cctacaacac cgactacacc taggattggt gttttttcag
    16981 ctgctagacc acgaacgatt ttttcaagtt cgttgatgtc catgcgatag ttgtggtcaa
    17041 ctggcactgg aatcacttgg tctaaaccga taccgatgat gtcggcagct tttagccatg
    17101 aatagtgttt agtttgtgga accaaccatt ttcctaattt ttctaaatgt tttccgctac
    17161 gtgctgagtg agctttgatt tcgtcgattt tttctgggac gctgtctaac agattcatga
    17221 tttcttctgt tgacaagttc attaattccc aatcgctttt tccagcaact agttcaggtg
    17281 tcacttcttt cattgcaagc ggcaatgatt tgatgttgcg ggcataccaa agtccttcta
    17341 agtttgctaa agaaccatca gcaacgatgt ggccccagcc atctttatag ctcattaatt
    17401 ttgcaaattc cattcctact tcttcttcca tttggcttgt tgcaggagaa gattcatagg
    17461 caacgttatt accattccat agcatagcaa aattgtacgc tagtaaagat ggcatcaatg
    17521 tttcagagtt catatgaccc cagtaacgtc cggcattatg ccaaggaacg gaatgggtac
    17581 gcatccgcgc tgaaatttct gatagaacat cctttgtttt attcacagtg tgttcaaaac
    17641 tagcactgct tttttcttct ggcgtaataa taggcatgtc ttgaggcatg tagttttgac
    17701 gccagcctaa atgttcatcc accaattcat tcaacaaagc tttatagatt tggccgttct
    17761 cagctttgtc cccaatgaat agggcattta ggtttagatc tttcgacaat gattcactca
    17821 tagtgaaacc ctcctaaaaa aatatttaaa ttttgtcgag ccctacatta cacctgttct
    17881 tctattctgt aaactaagtt ttggcctgat ttttaatcat attttaatat gtatcaatta
    17941 tccgaattgt tcacactttt gaaataatta aaaaaaacga gggaatttac aaatgtaaac
    18001 tccctcgcaa agattgtatt aacgacaacc agcgttctat tttaggatgg gtttcaaaat
    18061 tggaatgttg taatagtatt tccctttttc aaggtaaaaa cttactaaat tctaatcaat
    18121 tactttggcc aaaaagtaat ttttcttacc ttttcgaata accacaaact taccatcgaa
    18181 ttcatcggat ggatttatga caaaatttaa atcggtaacg cggtcaccgt taatacttat
    18241 agctccgttt gaaacatctt cacgtgcttg acgtttagat ggttcaattt ttgtggaaac
    18301 aagcagttcc acgatatttt caggtgtgct tgaaatttca acgttcggca ttttaccgaa
    18361 tccttgcgcg atttcttccg catttagttc tttaatattt ccagagaaca atgcttgcgt
    18421 tattttttgc gcttctttca agtcttcttc actatgcaca aatcttgtaa cttcttctgc
    18481 caaacggcgt tgtgcttcac gtttctcagg ttctgtctct acttttttcg ctaagtcttc
    18541 gatttcttct tgagacaaga aagtaaagaa tttcaagtat ttcactacat cgcgatcatc
    18601 ttgattcaac cagaattggt agaactcaaa tggtgaagtt ttcttcggat caagccaaac
    18661 ggcaccgcct gcagtttttc cgaatttcgt tccgtcagcc ttcagcatca atgggatcgt
    18721 taaaccgaac gcttctgctt ctggtccttc taattttcgg attaggtcta atccagctgt
    18781 gatatttccc cattggtctg ctccaccgat ttgcaattgc acatcgtatg ttttatgcag
    18841 atgcaaaaag tcgatagatt gcaggatttg gtaagtaaac tctgtaaatg agattcctac
    18901 ttccaaacgg ctggcaacga tatcttttgc taacatcgtg ttgatgttga agtttttacc
    18961 gtagtctctc aaaaattcaa gtaaagagat ttttgacaac cagtcgtagt tgttcacaaa
    19021 tgtgatattt gcatctttac caaacaattt tctcatttga ttggaaagtg cgtccacgtt
    19081 atgttgcact tgttccatcg tttgcaacac acgttctgtt ttgcggccgc ttgggtcgcc
    19141 gatcgttcct gttccgccgc caatcagaat atatggatga tggcctgcca attggaatct
    19201 tttcatcatc ataaatggaa tcaaatgtcc gatatgcatc gaatcaccag ttggatcaac
    19261 gccgcaataa agtgaaatgc tcttttcttc aacgagctcg cgaagtcttt cttcgtttgt
    19321 ttgctgatta atggcgtcgc gccaagttaa ttcatcaata atattcattt tactgacctc
    19381 cgtgtagttt ttttatgaaa gcaggaacct gctagcatat gtaattaatt atttcttcag
    19441 gataggatag gaaataaaaa aagtcccttg gcatataagc caagggacga aatctcgcgg
    19501 taccacccaa tttgtatgtc tagatatcca acatacctct cgaacattta acgctgtcgc
    19561 gtggcaatca ctgccaaaga ctcctgaaat gtaattcgct ttaaagcatg tactggtttg
    19621 cagcgaccac cagctttctg aaacattggc tttaacaact acttcgtttc gatcttcgtc
    19681 ttgttattat taatatgtgt ctatcataga gcgcaacttt ttctttgtca acagaaaaag
    19741 gatatttttt ttaaattcct cattttttct tttttgaatc cgctctaatt ccgaacattt
    19801 tattttcaat tattgttaaa agaaataact ttttctgtat tttttctgca atttatcgag
    19861 aagtcacttt actttgcctc ttattctttc ttcgttacaa taaggaatgg gacaagtaaa
    19921 aaaatgaaaa agcaagggac gaggtatatg gaaaaaaagc aaaaaattat tttaggagcc
    19981 acttctgctt taactatcgt tattttaatt ctaagtttgt tttttgtcat ccgatcatct
    20041 acaaaaaaag aaccaatcat tcctgaaaaa aaaataacag aaaaagcaaa agaaccgaca
    20101 gatgataagc aacaactagt tactcaagca aaaaatctgg ctcaaagcta cgattatgac
    20161 caagcgattg cgttattgga aaaagatagt aagaacggat ctactgaaac acaacagctt
    20221 cttcaaacac taaaaaagga gaaagaacaa ctgatcgact ggtctgatcc tactcagatc
    20281 tctcatgtct ttttccacag cttgatcgtg gacccgcaaa aagccttcca ctctcaacag
    20341 gcacaaggat acaaagatta tatggtgact gttgaagaat tcaaccgttc gatcgaacaa
    20401 ctttatcaaa atgattttgt tttagttaat ttgaatgatt tgatccaaaa agacgaacaa
    20461 ggaaatcttt cctttaacgg gcttgcgcta cctgaaggaa aaaaaccatt ggttctttca
    20521 caagatgatg tcagctatta tgaatatatg gataattccg gttttcctag ccgattggtc
    20581 gtatcaaata acaatgaaat caaaaatgtc tataaagaga aagataaaga agaaatcggt
    20641 gactttgaca tggttcctct gatcgatgcc tttgtcaaga aacatcctga tttttcttat
    20701 cgaggcgcaa aaggtacctt ggccctgaca ggttacaacg gagttttagg ttatcgaaca
    20761 tcaaaatctc aatatggaga caatgaaaaa acaaaaaaag agattaaaga agctaaaaaa
    20821 gtggcggaac agttgaagaa agacggctgg agctttgctt cccatacatg gggtcacttg
    20881 aatatgactc aagcttcact agaagatgta aaaaaagaca atgaattgtg gcagcaagaa
    20941 gttgcaccta tcctaggaaa aacaaatatt ctgatttatc catttggtgc agacatcagc
    21001 gactggcagc cttattcagc agaaaatcaa aaatttgctt acttgaagag tcaaggtttc
    21061 gatattttct gtaatgtcga tgcttctaca ccagcttggg gacaattagg tacggatttc
    21121 tatcgaaatg ctcggatcaa tatcgatggc attcgttttc aatctgattt agacggaaaa
    21181 aatcctattc ttgatccatt catcaatgtc catgatgtct atgacaaaga agcacgcgaa
    21241 tctgcttgat tttacgtcat ttatgaacca aaaaagccga actgacattt tatcgtcagt
    21301 ttcggctttt ttatgcttta tttcttcttc ggtgcgattc ccttgatcag gacttctgtc
    21361 cattctgctg tatatggaag cagttttgcg tatatctccg gcttagaaat tccttctacc
    21421 attgcttgaa aatagaggat caagaactca tccgaatatt tcaaatccac ttttccttct
    21481 ttccgccctc gatggaaaag atcaagcatg atactgaaac tttcttgcgt atacgcatcc
    21541 atcgcgtcag aaaattcttt tttttctttt tttgtatagt atgtcatcaa atcgatataa
    21601 aattgtttgt tcactcgatt gagataacgg attttgtttt cactcatggc aatcagtgtt
    21661 tcttcaaatg gaagattttc cgcaatcaac gctttcgctt cttgccctaa atcattcata
    21721 aatgcaaaaa atacttcata aatcagccct tccttgctgc caaaatattt aaaaatcgtc
    21781 gctttactta cctgagcgtt ctcagctacc ttatccattg tcactccagc ggttcctatg
    21841 tctgtgttca tcaagtcaaa agctgcttgt aaaatctctt tctttttctc ttgtgctctc
    21901 ttttcaaaac cgttcatttg tagagcctcc cgtaatttta aacttttata atata
//
LOCUS       DAZKCW010000044        21076 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000044 DAZKCW010000000
VERSION     DAZKCW010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21076
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.044"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(134..721)
                     /locus_tag="ACG84Z_001911"
     CDS             complement(134..721)
                     /locus_tag="ACG84Z_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162724.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            896..2218
                     /locus_tag="ACG84Z_001912"
     CDS             896..2218
                     /locus_tag="ACG84Z_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFP9162725.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            2373..3149
                     /locus_tag="ACG84Z_001913"
     CDS             2373..3149
                     /locus_tag="ACG84Z_001913"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFP9162726.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            3142..3711
                     /gene="rnmV"
                     /locus_tag="ACG84Z_001914"
     CDS             3142..3711
                     /gene="rnmV"
                     /locus_tag="ACG84Z_001914"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFP9162727.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            3704..4588
                     /gene="rsmA"
                     /locus_tag="ACG84Z_001915"
     CDS             3704..4588
                     /gene="rsmA"
                     /locus_tag="ACG84Z_001915"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFP9162728.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            5039..5668
                     /locus_tag="ACG84Z_001916"
     CDS             5039..5668
                     /locus_tag="ACG84Z_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162729.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(5792..6901)
                     /locus_tag="ACG84Z_001917"
     CDS             complement(5792..6901)
                     /locus_tag="ACG84Z_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162730.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            7110..7532
                     /gene="mgsA"
                     /locus_tag="ACG84Z_001918"
     CDS             7110..7532
                     /gene="mgsA"
                     /locus_tag="ACG84Z_001918"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFP9162731.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      7719..7817
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            7855..8391
                     /locus_tag="ACG84Z_001919"
     CDS             7855..8391
                     /locus_tag="ACG84Z_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFP9162732.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(8431..10194)
                     /locus_tag="ACG84Z_001920"
     CDS             complement(8431..10194)
                     /locus_tag="ACG84Z_001920"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162733.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(10197..11912)
                     /locus_tag="ACG84Z_001921"
     CDS             complement(10197..11912)
                     /locus_tag="ACG84Z_001921"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9162734.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(12691..12915)
                     /locus_tag="ACG84Z_001922"
     CDS             complement(12691..12915)
                     /locus_tag="ACG84Z_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162735.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            13106..15883
                     /locus_tag="ACG84Z_001923"
     CDS             13106..15883
                     /locus_tag="ACG84Z_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9162736.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            15964..16383
                     /locus_tag="ACG84Z_001924"
     CDS             15964..16383
                     /locus_tag="ACG84Z_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9162737.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            16395..16865
                     /locus_tag="ACG84Z_001925"
     CDS             16395..16865
                     /locus_tag="ACG84Z_001925"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9162738.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            16882..17661
                     /locus_tag="ACG84Z_001926"
     CDS             16882..17661
                     /locus_tag="ACG84Z_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFP9162739.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            17648..18469
                     /locus_tag="ACG84Z_001927"
     CDS             17648..18469
                     /locus_tag="ACG84Z_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9162740.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            18486..19535
                     /locus_tag="ACG84Z_001928"
     CDS             18486..19535
                     /locus_tag="ACG84Z_001928"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9162741.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            19548..20552
                     /locus_tag="ACG84Z_001929"
     CDS             19548..20552
                     /locus_tag="ACG84Z_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9162742.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
BASE COUNT         6776 a         3710 c         4309 g         6281 t
ORIGIN      
        1 gtgttaatta taagttctat cactttatgt tcaattagtt tgtgctctta tatgtgtgat
       61 tgaaaatata gataaaaaaa caatcatcgg ctttgacttc gatgattgtt ttctttattt
      121 tgtaaaaatc ctatcacttg attttatggt aaccttttat ttttgtcttc aaacggcttg
      181 gtaagagagc agtaagcagt gcaaatggga tcgaaaagac ataccagaaa atcgtacgtc
      241 cgataccata atgttgatag agctttgtca acatcacgtg taacaagatc aaccctaaaa
      301 gcaaggagcc agctataaac caatgattat cccaatgcat gacttcacta agtgccatca
      361 ctccaaaagg atagaaataa aaatagatcc cgactaaggt catccgccag ttctttgtaa
      421 atgttccgat attcaataaa aagaaaatcg ctgaaagcaa aataccgata ggcggaaaaa
      481 gcccaaccaa aaaggaatac aacatccccc acaagatcat cacaggacct ttgatcaatg
      541 caacgattgc gatgaacaaa gtcagcaata ttagtttttg tgataacgtt gcaacagtca
      601 ttaatccaaa taaaattaat gtgaaccaat gccaatggga ctgctgttgt tctttacggg
      661 aaaaatcgac ccggttggat aaataatctg ctaatttcgg ataagaacgc ttaaaatcca
      721 taaactgttc ctccttcgtg gaaaaggtag gtttagtata cgaaaaataa aaaagaaata
      781 catccgtctt aagagggagt ttttcactga aagtggagaa aaaagaatgg taaattaaaa
      841 tattctcagt tatactgaaa attataccaa atttcaaaga agaaagagga tgggaatgaa
      901 aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta gctaccgtta tgggaaccgt
      961 gatcggtgca ggcgtcttct tcaaaactgc tgctgttact gctagtactc agtctacaag
     1021 tttgacattg ctagcttggc ttttgggtgg tttcttaacg atctgtgctg gattgacagt
     1081 ggctgaatta gctacagcaa tcccggaaac tggtggagct gtaaaatata ttgaagctgc
     1141 gtatggaaaa ttgcccagct ttttattagg atgggcgcaa agcttgattt actttcctgc
     1201 taatattgct gcattatcga ttatctttgc gacacaattg acgaacttat tacaattatc
     1261 taccgattat cttttgttga ttgcagtgat caccgctgtt tctgtgacag ggttgaattt
     1321 gttagggaca aaagtcggtg cttctgtaca atcagtgacg ttgattgtta aattaatacc
     1381 aattgctgtg attgtcatat ggggattatt gaccccagga caaggaactg tccagttatt
     1441 tccaatcgaa gctggaaaag atgttacttt tgtcgaagga ttgagcagtg cgttgttagc
     1501 aacgttgttt gcttatgacg gctggttagg tgtcggtgca atggcagggg aaatgaaacg
     1561 gccggaaaaa gatttgccta aagcaattat tcttggtttg agttttgtaa cagtcgttta
     1621 tctattgatc aattttgttt ttttgaaaac tttgccgatt gatcatcttg ccggtaattt
     1681 gaatgcagct tctgaagcat cagacgtcat ttttggagga atcggtggaa agctggtcac
     1741 tattgggatc ttgatctcgg tatacggtgc attgaacggt tatacactaa ctgggatccg
     1801 cgtgccttat gcgatggctt tagaagacga gctacctttc agtaaacagc tgacaaagct
     1861 ttcaaagaag tttacggttc cttatgttcc tgcggttttc cagttagcag tagcttgtat
     1921 tatgatgagc cttggttctt tcgacttttt aacagacatg ttgatttttg tgatgtggct
     1981 attcagttta ctgattttta tcggtgtctt tattttaaga aaaaaagcgc cggaattgcc
     2041 acgtccatat aaagtaccac tttatccaat cgttccgatt attgcgattc tcggtgctat
     2101 tttcatttta ggtatgacga tgatgacgca aacgaaatta gcattgatcg gtataggtgt
     2161 taccttgata ggtatcccag tctattatca aaaaaagaaa aaacgctcag aagagtaaaa
     2221 tatttcaaca acagacagaa aaagtacgaa ctaggtcctc tagatcttcg tgctttttct
     2281 atttcaataa aacaagttct tctattttga tttttgctac ttctgcaagt agtgcttatg
     2341 tgctaaagta agaatgaaaa ggagagataa acatgatatt tgattctcat acccatttaa
     2401 atgctgaaca gttcaatgaa gatattccag aaacgattca gcgagcacaa gaaatggggg
     2461 taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat tgaaaagtct ttgcaattaa
     2521 gccatgacta tccaaatata tacagtatta tcggctggca tccgacagag gctggcagtt
     2581 atacgaaaga aatcgaaaat aaattacaag aacaattgac tttaccaaag gttgtagcat
     2641 taggggaaat tggcttggat tatcattgga tggaagaccc gaaagaagtc caagataaag
     2701 tatttcgcag acagattgct atcgcaaaag aaatgaacct accaatcagt attcatacta
     2761 gagaagcact tgaagacacg tatcaaatcc taaaagaaga agatgttcga gatatcggtg
     2821 gaatcatgca tagtttcagt ggtgattatg aatgggcaaa acgatttctt gacttaggga
     2881 tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc attagacgtc caagaggctg
     2941 cagcaaatgt accaatcgaa cgattacttg tggaaacaga tgccccttat ctggcaccag
     3001 ttccttttag aggaaagcga aatgaaccag gctatactcg ttatacagta gaaaagattg
     3061 ctgaacttcg gaatcttccg acagaagaag tggctgccca aacatggaca aatgcgcacc
     3121 gattatttgg tctaagcgaa catggataag atgaagatcc aagagattat agtcgttgaa
     3181 ggaaaagacg atacaagaag gctgcgggaa gtagttgatg cagatacgat agaaacaata
     3241 gggtctgcaa tcaatgaaga gatcctgatg caaattgaac atgcccaaga gactcgtgga
     3301 gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa taagaaaaat cattatggaa
     3361 gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac aagctaaacc aaagaaaaag
     3421 ggaagccttg gtgtcgagca tgcaagtgat gctgctattt tagaagcatt gaaaaaggtc
     3481 gtgacgccag acatttccca aacggctgtt tctgaaatca ctagacaaga ccttttagac
     3541 tatggtttaa tagctggggc acaagcaaaa gaaaaacgag aaaaactagg tgacgagttg
     3601 cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt tgaagatgtt tcgtattacg
     3661 ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac aacatgagtg aatatcgtga
     3721 aattgcgaca ccctctagaa caaaagagat tttattgaaa catggttttt catttaaaaa
     3781 aagtttagga caaaattttc tgactgaacc aaatatttta aggaaaatcg tagaaactgc
     3841 gcaaatagat gaacatacga acgtgatcga agttggacca ggaatcggtg cattgacgga
     3901 acaattagcc aagcatgcaa aacaagtcgt agcatttgag atcgatgatc gtttgatccc
     3961 tgtattggct gatacgatgc aaccctatga caatgtgact attgtacatc aagatatttt
     4021 aaagaccgat ttgtcaacag ctgttagaga aacatttcat gaggagcttc cgttaaaagt
     4081 cgtagcgaat ttaccttact atattacgac accgatcatg atgcattttc ttgaatcaga
     4141 tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa gtagctgatc gtatctctgc
     4201 tgaaccagga acgaaagctt atggttcatt atcgattgct gttcaatatt atatggaagc
     4261 cagtttagca ttcatcgtac caaaaacagt atttgtccct cagccaaatg tagattcagc
     4321 gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa gtgacagacg aaaaagcatt
     4381 tttccgattg acaaaagcgg catttcagca aagaagaaaa acgctttgga ataacttgca
     4441 gcattcgtat ggcaaagatg accagacaaa agcatggtta gcaaaaagct tggaaacagc
     4501 tggaatcgat ccaaaacgtc gtggggagac tttgtcatta caagaattcg ccgcattaag
     4561 caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg tgacagaagt tgtgaaaaag
     4621 ctgtcctgca tcaagtaata agaacagcca aacaaaaata gttcctcatg tttttcgttt
     4681 gtttgggctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag aggttgtggg
     4741 cctgccgttt aactctaagt cacaaggaac aatttcaaaa aacagcttct catgtttttg
     4801 agttagttgg tcttattact tgatgcaagc ttttgaccac tattatgccg aacaaggaga
     4861 tgtgacacaa attttgtcac atctcctatt tttgtttctt gatcaaaaaa ttcttatact
     4921 tgatactcac actcattttg tatggattta gaaaagaata tgtgtcttga cagttattag
     4981 taagtgagtt atactaagtc gacatttatg tgtcaagaca tattaggaga gagaaaaaat
     5041 gagaaaaaat tcagttcgaa aactaacgat ttctgcttta ttgattggga tgggggtcat
     5101 tatcccaatg gtcatgccta aaatcatgat tccaccagct tcctttactt tggcgtctca
     5161 tgtgccatta tttattgcga tgttttttac accaggagtt gcagtggctg ttgcgctagg
     5221 tacgacattt ggtttctttt taacaacgcc ggttatcatc gcattgcgag cattgtcaca
     5281 tcttgtgttt gcgttgattg gggcttggta cttgcaaaag catccgagta tcgttttaaa
     5341 aaatggacag tttacttttg ctaattggcg tttccaaggg ttcaattttg tgatcggtgt
     5401 gattcattct ttagcagaaa tgctagtagt cagcatcttt tactttattg gtaatatgcc
     5461 tgaaacatat tattctcaag gatattttta tacagtattc atcttgatgg ggattggtgg
     5521 gcttatccac agtttagttg attataatat tgcttatttt atagcaggaa cactcagcaa
     5581 atattttgat atccccgtat ttacggcagc aaaaaaagaa aatcggaaag agtcgattca
     5641 agggtacgcg aagaaaacga catattagac atgatctctc aaaaaaaaaa ctctcatcta
     5701 gtaatggata ataaatcctc taagatgaga gttttttgtc ctaaaaagag ctgcaccaac
     5761 atcttctggc acagctctaa cagggggcaa tttatggaag tttgatgact tgttctgttt
     5821 ctttatcaaa gaagtggcct ttgctgatgt tgaaggcaag gtcgactatt tcgcctggtt
     5881 tatggaaatc tcttgcatct acttttgaga tgaactcagt agaaccagtt tttgtgtaaa
     5941 gcatcgtttc agctccaagt aattcggaaa cgacaacttc tgatttcact acggcttcag
     6001 gtgaagcttc aagggctact tgttcactgt ggatgtcttc tggacgaata ccgaagataa
     6061 cttcttttcc ttcataacct ttttcaacta atactttgtt ttttccttca ggaatacgaa
     6121 gcttaagccc atgtccatct gtgataacac catttttcaa tgtcacatta aagaagttca
     6181 tggcaggaga tccaataaag ccggcaacga acatattgac gggtgtatca taaacttctt
     6241 tcggtgtacc gatttgttgg ataaatccgt ctttcatgat aacgattcgg tcagccatag
     6301 tcattgcttc tgtctgatcg tgagtaacat agatggtcgt tgtttcaaga cgctggtgaa
     6361 gtttggcaat ctcagcacgc atggctacac gtaatttagc atctaaattt gataatggct
     6421 catccattaa gaagactttt gcatcccgaa cgattgcccg tcccaatgcc acacgttggc
     6481 gttgtccacc agataaagca gctggttttc gtttcaagta ttctgtcaga cctaagatct
     6541 ctgctgcatt gtccacacgt tttttgatgt ctgctttatc atatttacgt aatttcaagc
     6601 caaaagccat attatcaaaa acagtcatat gaggatacaa tgcgtagttt tggaaaacca
     6661 tggcaatatc acggtcttta ggtgccacgt cattcatgac ttttccgccg atatttagtt
     6721 ctccttcaga gatatcttcc agtcccgcga tcattcgcaa agtagttgac tttccacaac
     6781 cggaaggacc aacaaaaacg ataaattcac ggtctttgat tgatagatta aaatcagtta
     6841 cagaataatt ttctgcattg tcatattttt tatatacgtt tttcagagcc atttctacca
     6901 taatacgttc cacactttct tttttagttt tattaactat ttaaagtata aatgaaagcg
     6961 ttaactaact tcaatgtcat gttgaacaag aattttttct tttttttgtc aatgtgctag
     7021 ttttaagctt taataaatat ccataagaaa taaaaactga tacactggag taaataagta
     7081 tgttaacaat atcaaaagga gtgtctctta tgaaaatcgc tttgatcgct catgaccgaa
     7141 aaaaacctat gatggtgaaa ttagcaacag cgtataaaac aatattggaa aaacatgaac
     7201 tttttgctac cgggacgact gggcagagga tcacggaagc aaccggcttg ccgatccatc
     7261 ggtttaaatc cggaccgtta ggcggggatc agcaaattgg agccatgatt tcggaggatc
     7321 agttagattt ggtgattttt cttcgagacc cgctggctgc acagccccat gaaccagatg
     7381 taacagcact tatccgttta tctgatgtct atgagattcc gttagctacg aatatcggaa
     7441 cagctgaggt gctactaaga ggactggaag ccggcttcct agattttcga agaatcgtcc
     7501 atgaaataga caagcatcca ctttcatttt gatggataag cgtatggaaa aataacgttt
     7561 aatgttcgcc tatatgtagc tataaaagct aaacaaactg ataatatgcg atataatacg
     7621 aacgtattgg ataatataaa caataatatt agtttttcgt atttgcagta aatgtgaaaa
     7681 tatgctatag tttctgtggg aaaagatccc aaaaataata cagagtagaa aataaagcgt
     7741 taagtgctaa gaggatggga tgttgcctct tggacgaagg acgtaatgtt cgcggtttta
     7801 ttttcgcatt cgctgcatga tacgatgtag cagctcttaa aggagatgct aaaaatgaag
     7861 aaacaccggt tagacgcacg tatgattgct attatgggct tattgattgc attgatggtc
     7921 actttgtccc gactggtagc aatcgagacc ccatttatta aaatcagtgt cacatttatt
     7981 ccacaagtga tcatgggcat tctttttggt cctttttggt cagggatagg cgcagtttta
     8041 gctgatttag taggaatggc cctcttctcg aaatctgcat tctttattgg atttacattg
     8101 aatgcattta ttgaaggagc aatctacgga ttctttttct atcgaaaaga gatcacttgg
     8161 aaaaatgcca ttctggctac gcttagtgtc acgctgatca tcaacttatt tttgacacca
     8221 ttatggcttg cgttgatgta ccatgtgcca ttgttcagct gggtcgtttg ggcgccccgc
     8281 ctgttaaaaa cagtaatatg gttaccgatt caatcaattg ccatttatta cgtaggacgt
     8341 agtattcctt acaaaaaaat tttaagaagt ttagcgatcc acgctaaata aaaaacaagc
     8401 agtcttccca tcccagaaga ctgcttgttt ttattgtgct gtgaattgtg cttgatagag
     8461 ccgtcggtaa taaccatctt tttgaagcag ctcatcatgg gtgcccattt cgacaatagc
     8521 tccctgatcc atcactaata tctggtccgc atttttgatt gtggacaggc gatgggcaat
     8581 cacaaaactg gtttttcctt ccatcattgc taagaaggct tgttggattt ttttctctgt
     8641 caatgtatcg actgagctgg tagcttcatc taagatcaac atagggggat tactgatcat
     8701 cgttcgagca atcgtcaaca gttggcgttg tccatctgat atctttaacc cttgaccgcc
     8761 aatcttagta tctaattttt ccggcaaacg ttctacaaat tcatacatat aagaggcttt
     8821 tagggcatca ttgatttctg cgtcacttgc ttccggattc ccaaaacgaa gattttctcg
     8881 caatgtactg tcaaatagcc aagtatcttg taacaccatt ccaaaacttt tacgtaatgt
     8941 atcacgttgg atagagcgga tgtcatggtc atcgactgta attgttcctt ttgttgtgtc
     9001 ataaaaacgc atcagcaaat taacaagtgt ggattttccg gcccctgttt ttcctactat
     9061 agcaatggtt tgacctggat aagcagtaaa attgaaatct tcgatcaaac gctgcttggg
     9121 gtcataagaa aaagaaacat gatcaaaaga gacttttcct ttgatatttt tgggttccaa
     9181 ggcataggca tctggcaaat caggcttttc ttctggctga tcgatcaaat caaatgctcg
     9241 ttctagacca gaaaaagcgg tttgcagttg tgtcgtgatt ccagaaagtt cgataaatgg
     9301 tttagaaaac tgacttgagt agatcgtaaa gctggaaatc acaccaacag tgattgacga
     9361 accactcttc aatgccaata ggccgccaac taaaccaatc gataaataag caaggtgatc
     9421 tacaaaacga gaagacgggt ttgtcaagga agaagaaaat tgtgcccgtt gtcctttttc
     9481 atatagatca gcatttagca gttcaaattg ctgttgacta gcttcttctt gctgaaaagc
     9541 tttcacgatt ttctggttac cgattcgttc ggtcacaaag cccgagatat ccccaataat
     9601 cctttgctgt ctatcgaaat ttgtttgtga agcacgagca acgatccaac tcacaaggaa
     9661 aataattggt gtagaacaaa gaacgaccaa tgtcagaagt ggacttagac gcatcataaa
     9721 aataaacgaa agaatgatga ttgccactcc agaaaataat tgattgaagg ccgcagaaat
     9781 tgcaatggaa atattgtcca tatcatttgt aaatcgactg acgatatttc cgtgggagtt
     9841 ttgatcataa taacgaagtg gcaatcgatt cagatgagca aatgcatctt ttcttaattt
     9901 tgcaacggat aagtaagcta accgattgct taacacttgg atgagccatt gactgactac
     9961 gttgattaaa acgataccac cgaatagaat aagtaaatgg aacagtcgat tgaagcggac
    10021 ctgtccttct ccaatcattt gatcgatact ttgaccaatt tgtaacgtca tcacaactgt
    10081 tgcaatccca ttgatgattc ctagtatcac agctagccaa atgtcttttg cataggcagt
    10141 aaggtaagga atgaatcggc ggagcgtctg caaggataat ttttttactt tcataactat
    10201 tcttcctcct gtgatgcgac gatttcctga tattctgctg attgagcaag taattcttca
    10261 tgggtaccct gagcagcaat cttaccttga tccatcacta agatatgatg tgcttcttga
    10321 atagagcgga cacgttggga gataataatc actgtactgc caagataagt ctgtagcgcc
    10381 ttacgcaaat ccaagtctgt ttgataatcc aacgcactta aagagtcatc taaaatcagt
    10441 aatgctggct tggcaatcaa agctcttgca atcgtcagtc gctgtttttg tccgccagag
    10501 aaatttttcc cattttccat gacttttgta tctaaaccat ttggaagctg acggacaaat
    10561 tcttctgcct gagcgatttt cagagcttcc caacattctt tttctgtggc gtctttctta
    10621 ccccattgaa ggttttcacg aatagtcccg gtaaatagta cagaagtttg gggaacaaga
    10681 gcaatttgct gacggagatg atccagctgc caagaacgaa catccattcc gtccattata
    10741 actgtaccgg aactgacatc atagaaacgc ggaatcaatt gtgtcaaagt cgttttcccg
    10801 cttccggttg gaccaatgat tccaaggact gtatttcgct tcagctgaaa tgtaatattt
    10861 tggagagaaa gaccagaatc aggagtataa cggaagtcaa catggtcaaa agcgataatt
    10921 gcttcagaag aaaaatcggg agtagtactg acctcagctt caagaatcga attttctgtg
    10981 tctagcacct ctttcacccg atttcctgaa gcttcggcac gtgtgaagat cacgacgagg
    11041 tttgaaacaa cgatcagtgc caaaagcatt tgattcatat aattgatcaa agcaagaact
    11101 tgtccttgtt gcaagctacc aatatttact ttgatcccgc caactgtcag caaacagatg
    11161 atcccgacat tcatgatcaa ggttgtagca ggtgataata gggcagagat attggaaaca
    11221 cgtaaataat tgttcgctag atcatttgtg cttttatcga acttctctgt ttcttttttt
    11281 gtctgcgcaa atgcgcggat gacacgaaca ccgctaagat tctgactaac gtgttcattg
    11341 agctgatcta gtttttcttg cactttttgg tagagaggaa cggttttttt gatgataaaa
    11401 aataaaatga ttgagaaaat aggcaataat gctaagaaaa acagacctac ttcccagtcg
    11461 atcacaaaag ccatgaccac tgacccgata cttaaaaacg gtgctctgat caataaacga
    11521 atgaccattg ctaaagctag ctgaagctga ttgatgtcgt ttgtcattcg ggtgatcaag
    11581 gtatctgttc caaaatgatt caactcgttg tgagagaaag tattgatttt tttgattagc
    11641 tgattacgta actctgtacc aaatccttgt gaagctactg aagcatagta ttggcaaatg
    11701 atagcacaaa tcagaccaat cacagacata gcgaccatcc ataagcccat ttcaatgatt
    11761 tttcctcggt cattcatttt tagtccatta tcgatcaagg aagccatcat taaaggcagg
    11821 acaagttcga agacagcttc aagaaatttg aagaacgggc ccaaaatgat ttgcttacga
    11881 tagtcttttg cataacgtaa taactgaatc atatgattcc tcctattatt tatttgtcca
    11941 caattgaaaa aacaagtact accacattgt agcttaggaa atttagaatg aaaagagaac
    12001 aagccttttc ataaatgaaa gttttattat gaagaagctt tagaaattga atagactatt
    12061 ttttttaaaa aaaagaaaat gagaaaacat gccagtctct tcattcatag gaacgtctat
    12121 tttacttaat ttttctataa atgaattctg cataaaaaat atatcaagta aatgtttata
    12181 gatgaaactc tatttacttc ttttttaatt tgttcttgca atcttttttg ctacgtaatt
    12241 tttgtaaaaa agtgggttga gagaaatcta attgattttc aaagaaggag tatgaaaatg
    12301 agaaaaatat ttattcgttt attgtgggta ctatcttaga ggaataaata atagtggaga
    12361 aaactatggt ttggcgcaga ttctatcagg tttgatggaa cgaagacaac ctcccgacat
    12421 caagtcaaaa gctacttgag attttgatct gaaaataaaa aaagaaaaca aggtaggaac
    12481 atcaatgttt ctaccttgtt ttcgtaatca atgggaaaaa actaagagtg gtgtacgtaa
    12541 tcaataaaaa ggatggtgac aacagtacct ctttactctc tgaaagcatc ataactcgtt
    12601 tttcctcatt atgccaataa attgttgtta taccacatat aaggatttgt aatagctaaa
    12661 aacagacagg aaagttgaaa tctgtgaatc ttattttgta tggaaggatt tatagaacgc
    12721 aaaaatcaag ataaagatga ataaaaatcc tgtttcggct atatattgcg tatctacgcc
    12781 aataaaacga gtttgttctg tcatagccat ataaagcaaa ggcaaaaata caactacagc
    12841 gagataagat ccgatgattt ctcgaaaagt tttccaggaa gtatgtttcc tgtttttata
    12901 tttatccgat ttcattgaat agtcatagcc tccttattct ttcatatgtt gaaattccag
    12961 tataaaaact ggaaggaact gtacgttttt tagaataaaa attataaggg ataagtaggc
    13021 tgctgtctat aataagatat atttttcaat tctttattaa agattttatt gacaaaatga
    13081 atccgttttc tatgatggag gaggggtgaa taagttgttg aagaaggaaa ttttatgtta
    13141 cttagagaac cagacagcct ttttcgattt agaacatatg aacgaggtct ttacagcaca
    13201 aaggttagct gatcattttg gggtaaaaag aaacacagtc agtcattatt tgaaccagtt
    13261 aaatgatgag caactactag tcaaaatcaa ttctcgacca gtgatttatt tccacaaaga
    13321 agcttttgaa aaacaatttt ttaagttacg cacgaatttt tatttttcta tcgatgatct
    13381 caaagaggaa cagccttttt tcgcgcaacc aaaagactta ttctctttta tgatcggata
    13441 cgacgccagt ttgaaagaaa gtatcgaaca aatcaaaaca gctctttact atccagatgg
    13501 cggattacca cttttgatta caggcgaaag tggcacaggt aaaagttatt tagttaattt
    13561 ggtctatcag tattgtctgc ttcatgatct gctagaagat tctgcaccat tcatcacttt
    13621 taattgtgca caatatgcag ataatcctga acttttgact agcaatttgt ttggacatgt
    13681 taagggagcg tacactggtg cagaagaaaa taaaaaaggg gcttttgaag cagcagatgg
    13741 tgggatcttg tttttagacg aggtacatcg cttaacacca gaaggtcagg aaaaactgtt
    13801 cacctatctt gatcaaggtg tgatttatcg tatgggagaa cctaatttgt cacgccggat
    13861 caaaacacgt ctcttttttg ctacgactga agagattact agtcatttct taacaacttt
    13921 cattcgaaga atacctatcc gaatcgaact acctgcactt aatcagcgta gtcgtaatga
    13981 acggctagaa ctgatttact ctttttttct cgaagaacaa agaaaaatgg ggagcccttt
    14041 gtcagtcagt ggaccagctt tgtcactttt aacaagtcag aaattatccg gaaacatagg
    14101 agagctgaaa aatatcgtca aagtttcagc agcaaaagca tatgctgaac agcgtgaaca
    14161 gcctgaaatc catgtcacga tccatcattt gcaaaaagaa ctacttgcgc agcctattac
    14221 taaaaataca gcacagcaag gaatctatat tacgcaagac cagaccttag agcaattaat
    14281 ggagaagcaa cagcccgaac agcagcgaat cgttaaaagt tttgagcaaa tcctaattga
    14341 tttcaagaaa aataactgtc tgctatattc ttgcgaagga aaattaaagc aagaagtgat
    14401 tcaattattt gattttttgc tgtttgagac cagtagacaa gaaaaacacg agctgctggt
    14461 ttattggaca caatctatcc gagagacctt tcgacaaatg gaaactgcct atcaaatcaa
    14521 attcgatgga aacagtgtct atgccttgag ttactatctc tatcagcgaa gcactatcaa
    14581 atggttaccg gaagaacatg atattatcca actaatcaaa gaattagaac aacaagtttc
    14641 tcagtcttat ccatctagtt atcactatgt ccaacgaatt ctggaattaa gtaagatcaa
    14701 attagatatt gaagacacaa gtatggatcg gattttactg acgatctatc taaaaaaagc
    14761 gaaatggtca aaagaaaaac gactgccaaa agcgatgatt gctgctcacg gttatgcaac
    14821 tgctagcagt atggcaaatg tagtaaatcg tttattacaa gaggatctat ttgaatcatt
    14881 tgatatgcca ctagatgtca caccacagca gattgcttca gaaatccttg attattgcga
    14941 aaacagcgat gtttcaaatg gattgatcat attagtagac atgggatctc tgaaagaaat
    15001 ccatcagttt tttaaaaaac agttatccgt accgcttttg attttgaata atgtgacgac
    15061 acctttagca atcacagtag gggaatgcct gcaaaaaaat gtatcattag aagagatagc
    15121 agaagagact gttcgacaga tccagccaga atggcgactg ctctatccag aggaaaacaa
    15181 acccaaagca ctcattacta cttgcttcac tggaatcggt acggcggtcc acttaagtga
    15241 actgctagaa aaaagcttac ctacggcttg tcagttgaaa atcatcccat atgaatatca
    15301 gcaattaaaa gataagaaaa acagtgaccc attattttcc atatacgaag tcgtaggaat
    15361 gattggcacc acagatcctg atatcaccaa tatcgactat ctttcattag aagacctcat
    15421 ctcgggggaa aagatgtctg tactagctga atggttggac actactatga atgcttcaga
    15481 gaaggaaata ttcaatcagc gcatcattcg taatttttca ttggaaaaag tactggattc
    15541 cgtgactatt ctagatacag agaaggtgat gggagaaatc gatcatttta tgagagaatt
    15601 agaggtgcag ttgaatcgaa gcatcagcaa tcccaaaaaa ttagcgttgt atgtccatgt
    15661 gagctgtctc attgaacgat tgatccgaca aatgccaatc gaaacctatc aaggattaga
    15721 gaaatggaag cagtgtcaaa aagaagggtt atctgctatt aaatctgcgt ttagtgtcat
    15781 tgaagagcat tatagtgtca tgatccccaa ttctgagatt gcctatatct atgatatttt
    15841 gagtgaagat acagagtttc tctcgataga agaagaattt tgaacataag caagttgttg
    15901 ccactaattt tggcatgcaa cttgcttttt tagtatgtgt aagtgaaaag aggagatgaa
    15961 aaagtggata gagaaattat cttagcttcc catggaaaat ttgcttcagg gatattagat
    16021 tcattagagc tgatctatgg gaaaaatcat tctattactg tattcgattg ctatactgat
    16081 gagaattttg atttagcgga aacagtaagg cagcttttta tgaggtacaa agataaagaa
    16141 atcattgttc tgacggatct ttttggcgga agtgtcaaca acgaattctt acaatatatc
    16201 aatcgggatc atgtctatct cgttgccgga ttgaatttgc cactattgat tgagctagta
    16261 tctcggttgg acgctgaagt agagacaact gttttgatcc agcaggtgct aactgattca
    16321 aaaaaaatga tccagttttg taacgagcgg ctcaatcaga aaatagaaga agacgaattt
    16381 taggaggaag aaaaatgatt gtattgacaa gagtcgacca tcggttatta cacggacaag
    16441 tagctttttc atggacacaa acaataggcg cagactgtat tttgattgct aatgatgatg
    16501 tacctacgaa tgagatacga aagacaacga tcaaattagc caagccacaa ggagtcaaac
    16561 tagtgatcaa atcaattgat gactcgattg ccgcgttgaa aagcggggtg acagataaat
    16621 ataagttatt catcgtagtg gaatcgatcg aggatgcata taagctggca gaagcgtatc
    16681 cagaaatcaa aaccatcaac ttaggaggga tcaaggcaaa acctggtact cgcagcatcg
    16741 gaaaagcggt aaatatttta ccagaagagg aggaacgctt gaaacgatta attgacaaac
    16801 aaatagaagt agaaatccgt caagtaccag cagataaaaa agtggatgta agagaagttt
    16861 tgtaagaaag gaagaacctc aatgattgta caagcagtct tattaggaat tgttgcattt
    16921 gtcgcacaat cagaatatgc actagggaca tcgttgcttt ctcgtccgat tgtgacgggg
    16981 ctgtttacag gaatcgtgtt aggtgatgta aaaactggga tcattatggg cgcaacttta
    17041 gagttagcat ttatcggatc gttctcagta ggtgcttcga ttccacctga tgttgtgacc
    17101 ggtgggattt tagggacggc ttttgctatt acagctggag ccggtacaga aaccgcgctt
    17161 ttactaggtt tgccgattgc tacgttgaca ttgatattga aaaatattta cttagggctt
    17221 ttgattccaa ttatgaacca taaagcagac aattatgcag aagaaggaaa ttataaagga
    17281 gtcgagcata tgcacttgct tgccggtatc ggtctttcct tgatgcttgg tgttgtggta
    17341 atggtttctt atatggtggg aagcaatacg atcggaaatc tattaaatat gattcctgac
    17401 ttcgttcaaa aggggttgtc agtagctaca gggttgattc cagctcttgg ttttgcgatg
    17461 cttgctcgtt tgctgatcaa caaacaagtt gcaccatatt ttttcttagg ttttgctata
    17521 gcttcttact tagagattcc tgtgaccgga gtagctattt ttggtgcgat tttagcagtt
    17581 gtggtagtca atattatgaa tgtccgtcaa ctaccacttc aaacaactgc aggggaggta
    17641 gaagaagatg aagaattctg agatcaaaaa cagcaaaata acgaaaaaag agctaaatca
    17701 cgtattttgg cgttcttttc aaatggagtt ttcttggaat tatgaacgtc agatgaatat
    17761 ggcttatgtt tatgcaatga ttccgatttt gaaaaagtta tatcagtcga aagaagaaat
    17821 ggcagcagct ttgaaacggc atctagagtt ttttaacacg accccacata tcgttacact
    17881 gattttagga atcacggctg caatggagga agaaaataag gatgatcctg aatttgatgt
    17941 gactgcgatc gatagtatca aaacatcttt gatgggacct cttgcagggt taggagattc
    18001 tttcttttgg ggaactttgc gattgattgc cacaggtgtg ggtacctctt tagccatgca
    18061 aggaaatatt ttaggcccta tcttgttcat tttgattttc aatattccgc acattctgtt
    18121 tcgctatcta gcaacaggtt ggggatatcg cttaggaacg ggttttttga aaaagatcca
    18181 ggcaaacggt atgatggaaa gtttgacatt aggcgcgtct attattggac tgatggtcgt
    18241 tggagcaatg actgccacga tgatcaccat caatattcct ttaaaaatcg gttcaggaga
    18301 aaatgctgtg actgttcaaa gtatttttga tgatatcgtt ccaaatatct tatgtcttgg
    18361 agcatttggc atagtgtttt atctattgaa gaaagaagtg aaaccattaa cgatcttgat
    18421 cggactagct ttctttggaa tttttggttc gtggataggg attttttaaa aaaggagcag
    18481 agaaaatgtt tacgatgcaa gattatatct atgaagaaaa ggaagtacta agtacgatct
    18541 tgaaaaagaa tgatttttcg acaagagaac atatgaaaaa aacagtgaat ttactgatct
    18601 tagcaacggg ttcatcttat aacgcttgtt tagcagcgaa gccagcattg gaatcttatg
    18661 gtgatcttac tgtcgatatt caagaacctt tttatttttt caattatgga aaactttctc
    18721 cttcaatcga tactgtgatt gctgtgtcac aaagcgggaa aagtgcttct actgttgaag
    18781 cagtaaaaat gatacaaaaa caagggttac ctgttgttgc tatcacaaat gacgtgcaaa
    18841 gtccacttgc tttagaagct gcacaaatta ttgatttagg tgccggggta gaatcagtag
    18901 gcttcgttac aaaaggctat tctgcgactg ttttacagtt actactctta gggataggaa
    18961 ttggaataag taaaaataaa atcagcaaaa aaatagaaca agactacatg caacagttgc
    19021 gcaaaataat caaccattta ccagcgatta ttcaaaaaac ggaagaattt tttgatggat
    19081 atcaaagttt atttcgttta gcacagcgtt tcgtcaccat tggatatggt ccaaactggg
    19141 gaacagctaa agaagcagag acgaaattga ctgaaacaat ccgcgttccg tcacaaggat
    19201 ttgagttaga agcttatatg cacggcccat acctggaggc agatgcttcg catttgctat
    19261 tctttattga aggggaaagt gtaaataagg aacgttcgca aaagttgcaa agatatatga
    19321 gtcggtacgt tggagagact ctcaccatta ccacaaaaaa agcaagaaac gagaaaacac
    19381 ttggattagc aatagaatgt gatgaatatc tgtctgtatt agcgcttgtc gttccgtttc
    19441 aactattcgc ttataaaacc gcagtagcta aaggtattga cttgaacaaa aagatttttg
    19501 aagactttga tacagtcttg aaaagtaaat tataagaggt ggaaatcatg ctgaaattca
    19561 atgaagaaga acaaatcaaa gcaataaaag gcgcactagc tttacgtccg caagtagaag
    19621 aaatcatcga taaactttat gcggaaaaat ttgacgctgt ctattatcta ggaatcggtg
    19681 gaacgtatgc ttcctcgatg caagctgtca cttatatgaa tgggaaaagc aacttgcctg
    19741 tctttgtaca gcatgctgca gaatattaca ctactggaaa caaaagatta acaaaagatt
    19801 ctatcgttat tttgtcctct gttaccggta caactcaaga agtagtgaaa gcagtagaac
    19861 aaatcaagaa agtaggagcg acactgattg gatttatcga taaagcgaac agtaagttgt
    19921 ctcagctatg cgattttgtg gtcacttatc cagctcctgg aacagaacaa atcaaatttt
    19981 ttatggcagc agatcgattg atgtatttga atggagaatt cgaagcttat tcagaatact
    20041 atgaacagct cgaacgttat ttaccaacag ggttagtgga agcagagaaa aaagcagatg
    20101 catttggctt atcatttgca gaaaaacatc gacgtgatag tatgcattat tttattggag
    20161 cagggaatca atggggagct gtttattcat atgccatgtg ttactgggaa gaacaaagct
    20221 ggcttccatc gaaatctatc catgctgccg agtttcttca cgggacgtta gagatcgtag
    20281 aagaaacaac cccagtcaca ttatttttag gcgaagatga acagagagtg ttatctgaac
    20341 gtgtggctaa acttttgcca aaaatttgca gcaattatac attgatagac acaaaagact
    20401 atccagtaga aggtatcagt gaaaaatatc gcggacgtgt tttgtctttc ttattgatgc
    20461 atgtagtgac acaacgcatc gatgctcatg tggagcagtt gaactgccat ccattagaga
    20521 tacgccgcta ctatcgtcag tttgattatt aggatagact ggataaaaag aatataaaaa
    20581 ataaagagag cagcgataac tgctcccttt atttttttaa aatattggca tcaattacgt
    20641 tataaaacac attttttgca ttatctacag ttcaacttat aatctgttta atgggacatg
    20701 tgggtgccaa ccattttttg ttatgcaata gtactattta gttgttgcat ggatccgtag
    20761 taaaagtcca agtacaacga gttgcgccag tttacatagc gttttgtatc cagaatgttg
    20821 actaaaacaa aagttcctat gtcaaccgtc aacagagaca atctgtccgt tgcaggacct
    20881 gacagattta gaaatgttca atctgtctct tatgtatttt aaatcaatac tcactaggag
    20941 aagtttccta acctcctaat agtaatgctg gtagtaacat tgtcaaaact gcttcctctt
    21001 aggaacaagc aaagcataac gagtgtaaaa ataaaatgta gactattgta acatatcatt
    21061 gattatttca agtaaa
//
LOCUS       DAZKCW010000045        19648 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000045 DAZKCW010000000
VERSION     DAZKCW010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19648
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.045"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(66..266)
                     /locus_tag="ACG84Z_001930"
     CDS             complement(66..266)
                     /locus_tag="ACG84Z_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9162743.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(718..1038)
                     /locus_tag="ACG84Z_001931"
     CDS             complement(718..1038)
                     /locus_tag="ACG84Z_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162744.1"
                     /translation="MKKRVLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(1541..2659)
                     /locus_tag="ACG84Z_001932"
     CDS             complement(1541..2659)
                     /locus_tag="ACG84Z_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162745.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPEIEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            2892..3014
                     /locus_tag="ACG84Z_001933"
     CDS             2892..3014
                     /locus_tag="ACG84Z_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162746.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            3130..4437
                     /locus_tag="ACG84Z_001934"
     CDS             3130..4437
                     /locus_tag="ACG84Z_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFP9162747.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGESRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANMFVIGWRRVAEFFGNLF"
     gene            4556..5755
                     /locus_tag="ACG84Z_001935"
     CDS             4556..5755
                     /locus_tag="ACG84Z_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFP9162748.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(5782..7050)
                     /locus_tag="ACG84Z_001936"
     CDS             complement(5782..7050)
                     /locus_tag="ACG84Z_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFP9162749.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKAEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(7105..7171)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(7213..7860)
                     /locus_tag="ACG84Z_001937"
     CDS             complement(7213..7860)
                     /locus_tag="ACG84Z_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HFP9162750.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(8268..8771)
                     /locus_tag="ACG84Z_001938"
     CDS             complement(8268..8771)
                     /locus_tag="ACG84Z_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFP9162751.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(8894..9658)
                     /locus_tag="ACG84Z_001939"
     CDS             complement(8894..9658)
                     /locus_tag="ACG84Z_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFP9162752.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMALTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFMVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKENAESLNVGVAAGIVLYHFSL"
     gene            9766..10041
                     /locus_tag="ACG84Z_001940"
     CDS             9766..10041
                     /locus_tag="ACG84Z_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFP9162753.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEEDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            10718..11668
                     /gene="yidC"
                     /locus_tag="ACG84Z_001941"
     CDS             10718..11668
                     /gene="yidC"
                     /locus_tag="ACG84Z_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFP9162754.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(11847..12821)
                     /gene="lacD"
                     /locus_tag="ACG84Z_001942"
     CDS             complement(11847..12821)
                     /gene="lacD"
                     /locus_tag="ACG84Z_001942"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFP9162755.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(12818..13276)
                     /locus_tag="ACG84Z_001943"
     CDS             complement(12818..13276)
                     /locus_tag="ACG84Z_001943"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFP9162756.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKDVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTKIATILTKEIGEDL"
     gene            complement(13273..14739)
                     /locus_tag="ACG84Z_001944"
     CDS             complement(13273..14739)
                     /locus_tag="ACG84Z_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFP9162757.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDASMGMMVPVLAAYIAEGIAKRPGLIVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDDSKAANRTVIEKGRAGDLS"
     gene            complement(14721..15671)
                     /gene="pfkB"
                     /locus_tag="ACG84Z_001945"
     CDS             complement(14721..15671)
                     /gene="pfkB"
                     /locus_tag="ACG84Z_001945"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFP9162758.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIREERFERWENIN"
     gene            15814..16563
                     /locus_tag="ACG84Z_001946"
     CDS             15814..16563
                     /locus_tag="ACG84Z_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFP9162759.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINVLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISQKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
     gene            16829..18307
                     /locus_tag="ACG84Z_001947"
     CDS             16829..18307
                     /locus_tag="ACG84Z_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFP9162760.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(18375..19466)
                     /locus_tag="ACG84Z_001948"
     CDS             complement(18375..19466)
                     /locus_tag="ACG84Z_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFP9162761.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT         6059 a         4025 c         3405 g         6159 t
ORIGIN      
        1 aagaaaatag acaaaaacgc ccagacacgc aaatgtctgg gcgtttattt tttagtatag
       61 gttaattaag ctttagtaac gtttgttgct tgaggtccgc gttggccttc ttcaacatcg
      121 aaagttactg cttggccttc ttctaaagtt ttgaatccgt cgccttggat agctgagaaa
      181 tgaacgaata catcgtttcc gttttctgca gtgatgaatc caaatccttt ttctgagtta
      241 aaccatttta ctgtacctgt ttccataata aaaatcctcc ttgtgtatca acacatattt
      301 tgcaattact tgaatggtgt atatctggaa gatgtttatt tgaaacaagc taccacagat
      361 taccgaacaa aaactactcc tatagtatat cataccgttt acaaaaaagc tagagttttt
      421 cgactttttt tattaaaaaa agttttctca gcgattacat aaagtgaaaa accgaacttt
      481 ttttaaaata aacgaaatat tgttcagttg gtgttttttt gctctgatgt tcttctttaa
      541 actaaaaaaa ttattctttc tgactactta tcggttctgt ttcaacggtc gaggctgggg
      601 aagattcttt agtaggtctg atgttctcat ggtatttctg atagcctatg acagtgacca
      661 gaagaacaag gcaaaccaat acgatcaacg agattagttt ttcttttttg ctcatatcta
      721 tacctcataa ataacaggat gatgtccatc atatttctga gtatgagtaa aagcaaaagc
      781 tgcagctgta gaatgtaaga aatgccagca actttcataa tcacaggtcg gacagtacca
      841 aaagtaacca aatcttggct gcaaagaccg ttcttctgtt tcaggaatcg cagaatcaag
      901 atctgttgtc tgtacataaa catttttgta cagacgtgtg cctgtaatag gagaccgctg
      961 tgtttcttca gcaaaaactg gctgacttgt taaacttagg gatagaaaca gcaaacacca
     1021 taacactctt tttttcataa agacctcctt atcgataagt ttttcccaat taaaatcata
     1081 tctcaagaac gcccgttatt cacattttgt tcataaatga tgttttttgt atcataatcg
     1141 tcaaaaagag gtcgtgacca cgtcacaacc tcttttttaa atggtgttcc agaagtagct
     1201 tcttcggaaa taagccgaaa tttcacaaaa atttgagaaa taatttttgt caatctcttc
     1261 ttatttcttg aagctgacca cttctgtcac aacctcttcc ttaaacggtg ttcaaaagct
     1321 tgcatctgcg gtaataagcc caccaaacaa aaaatatgaa gagctatttt tgcttgctgt
     1381 tcttattact tgatgcagaa cagctttttc acaacctctc atacacggtg tttaatcagc
     1441 tgaccttcgg tattagctca aaaaacggca aaatatgtga aactattttt ccgtttgttt
     1501 ctctaatact caggtcaaaa cactgttttc acaacctctt ttaataacga agaatcgctg
     1561 tcagactctt ttcatctggc gcatcttttt gatccaaaat aaacactttc ccgccattaa
     1621 tgatcacatc atctgctaat gcattcaaca cttgacgccg atcatattct atttcaggat
     1681 cttcaccgaa accatcagct aagtttgacg tagcgataaa tagatgcgac acttttcctt
     1741 ctttcgcagc tggaacgata tcaactaact gatcgatgaa tttcttatct aagagtttat
     1801 tgtattcttt tgattcttga gctgcgagtt cacttgacag cttcttcgcc ccttcttcga
     1861 tatctctaaa ggatagctgc gcaggagaag cagaaatcgc aacgtctgca caataatagg
     1921 gatttttagc aatttttttg aacatcgtct gattttctgg taatgcaaat aaataaatcg
     1981 gccattgttc tggattttcg aaagaatcct tcaagtacgt atcaacagct tggtaatagt
     2041 tgacccaatc gatctctact tcttcatctt ttggatttac gccatggaaa gttactccat
     2101 ctcgggctcc gcctcctcca ttagaagaga agttcaaacc gccacctgtc agttcagatc
     2161 ccaatgcagt aacgacatca accggtgccc cttctggtag agatacttct tttacttgtt
     2221 tgttgctgac ttcatacaat ttcatggagt cgcggttcaa tcccaacaga taataggaat
     2281 agttgaactg tccatttttg ataatggcca gtaaataagg aagatcactt acatagtatt
     2341 gatcgtctac cgggatactc aaacgatgga tataggtttg gtcagcagtt ataatgaccg
     2401 ctacactcgt agttgcacta cgccaaaacg aaggatctcc taacaaattt tcaatttttt
     2461 cttggaacgg ggaccagtca tgttcggaat attttttctc aaaacgtttc tttgcttctt
     2521 tcgcaaaatt tttgaatttg atttgatctt tttccacatc ttgatgggcg acatgcgtat
     2581 tcagcatgat cgtgacgaat ggtcctttag cgccttctga agtcaattgt gacaataatt
     2641 ctttatcctt ttttgccata aacgtacccc tcctaaaaaa atcattcctt tgtttctatc
     2701 taaagtctac cacaacacta tttttccata caataaaacg tatctaaaaa aataaaacgg
     2761 tttctacggt tttaaattta gctatttttt taagttatct tcataatttc ctcaattatt
     2821 tagccccagt cttcaactat tcttcatgaa atgctgataa actaaaaaaa agaataaaag
     2881 aggtggatct tatgcatttg attatgattt tcagtttatt aagtattatc agtttatttg
     2941 ctttcagcgc ttcccgctta ttagatgcgg aaacacagcc tattcctgta aaagtacgta
     3001 aaaacgaccg ctaaccttcc ataacgtgcg ttcttatcct aaagtttttt cagaaacatt
     3061 gaaactctct cccctctctg ataaaatttt aatttgtagc gaaacaaatt aattacaagg
     3121 agatcggata tgtccataaa aaaaacacgt ctagtcctat tattggctag tctcattctt
     3181 tgccttgctt cttttctacc agctgttgct gtgcaagctg aagatacgtt caaagtaaat
     3241 gcaaaagcag cttttgctgt agatgcgcaa agcggtaaga ttctttatga tcaagatgga
     3301 gaaaaaacca tggggatcgc ttcaatcaca aaaatcatcg gtctttacat cgttcttgat
     3361 caagtaaaag aaggaaaact atcatgggat gataaagttt cgatttcaga ttatgcagaa
     3421 aatttgagta tcaccccaga tttatcgaat gttcctttgc ataaagaaaa cacctacact
     3481 gtcaaagaat tattcgactc tgcaatcatc cagtcagcca atgcttcaat ggtggccttg
     3541 gcagaaaaaa tctctggcag cgaagctaaa ttcactgaac gaatgaaaga acaattgaaa
     3601 gattggggaa tcaaagatgc aacgatcgtt aatgcatcag gactgaataa ctcttatctt
     3661 ggcgaaagcc gaccagaagg tactggagaa aacgacgaaa atcaaatgtc tgctcaagat
     3721 gtggccatcg tggcccgtca tttgatcttg gattttccag aaatactgga cgtatctagc
     3781 actacgacac aaatgtttgg cgaaaacacg caatcaccag tggaaatggt caactggaac
     3841 tggatgctcc caggattcgt taattacaag gaaggcgtgg acggattaaa aactggtacg
     3901 actgagcttg caggtgcttg tttcgttggt acgatcacta aaaacgatca acggatcatc
     3961 actgtcgtat tgaatgcgga cggccatgcg gaaaacccga gtgcccgctt caatgaaaca
     4021 gaccgtttga tggactactg ctatgacaat tggtcagaaa aagagctcgg aaaagctaac
     4081 gcaagtattc ctagcctaaa aaccattgat gtaaaagacg gaaaagaatc aacagttcct
     4141 gttgtgctta aaagccctgt aaaagtatgg gtacgaaacg atatggatac tggcaaatta
     4201 acgatcacgc caacacttga caagaagcaa gtcactgaca acgagatcca agcacctatg
     4261 gataaaggta caaaaatcgg taccgctacg atcaccttgg cagacgataa attaggctat
     4321 ttagaagaca acaatgcgcc atcaacagag atcattacgg ataaaacagt ggaaaaagcg
     4381 aatatgttcg tgattggctg gcgacgcgtc gcagaatttt tcggcaactt gttttaattg
     4441 aacaataaga aaagcatctt tccatcggaa agatgttttt ttgctttttc tagtttaaat
     4501 aacagctttt ttcatctatt ttcgttatac tgtataagaa aaaggagttg aatttatgaa
     4561 tctaaccaga gatctgatct ttttagttct ctatcttatt ggggtattct ctatcgttta
     4621 ttggcgaaaa cagaagaagg atccttcctt gttcttttac ggcagtacgt ggacatttac
     4681 ggtaatctta acttattttg tcgtgttgga aattttttat tcgacctttt attttttgat
     4741 tccattgttg ttctttagta tctttgcttt ttcttatttc acagaaaaac gaaggctgct
     4801 gaatggtctt ttattcaatg ttttcctcat cagtttcggc atctacttgt ttgtcttgct
     4861 gtatgaaacg caaaatattt tccttggcgg actgatcgcc ttgatcacga ttccattgct
     4921 acttgtcctt ttatttggta tttatggatt gattgttttt cttttttgga acggggtcac
     4981 agttttacgt agagaatcgc attcattagc gaatctttta acgttgatac tagccatttt
     5041 tcttacactg tttcttgttt ttgacttttt cttgttaaaa tatttgccgc aatggataaa
     5101 tgctttgttt ttctgcgttc ccctgatctt gatctatcta tttatcgtat tctacaactt
     5161 tttgactgtc tcattcttgt accagttcaa ccggcctcga tacaatcaag acttcatcgt
     5221 tgtgttaggc gctgggttga tcaatggaga aacagtttct cctcttctag ccaagcgaat
     5281 caataaggca attgcttttt atcgggctca aagccgtgct acattaaatc cgcccatctt
     5341 attgatgtct ggcgggcaag gagcagacga aaaagtacca gaggccattg cgatgaaaca
     5401 atatgccatg gaacaaggaa tccctgaaag agacattctt gtcgaaacca attcgacaac
     5461 cactttggag aacatgctct attcaaagga aatcatggat cagcaaatga aagggccata
     5521 ccgcgcgatc tttagttcca acaattacca catttttaga gccggtcttt atgcgcggca
     5581 agccaaattg aaagcaaatg gtattggtgc aaaaacagct ttctactact tgcctaatgc
     5641 gtttttaaga gaatacatcg ccatcttgat gatgaacaaa aaaagacata tgatcatttg
     5701 cggattgctt ttcgcaggct ccgcattctt atcgctgatt actttacttt tctaaaaaaa
     5761 caaggtgtga caaaacatat gtcacacctt gtttttttct ttcattctct taactattgg
     5821 caaaaagagt atcccttttt tgaccgctac ttgctgagca gaataaatac cgctgttgcc
     5881 tgaacacata aagctgatca agcagatcat aaagaagtaa acagccgctt gtgaaccgaa
     5941 caattcgatc cccatcacaa agcaggcaat cggtgtattt gtcgcaccag aaaatactcc
     6001 gataaagccc aatcctgcga gaaaaggaac agaaacatgg agcaaaggcg ctagtgctgc
     6061 accaagcgtt gcaccaattt caaacaatgg tgtcacttct cccccttgat atcccgcgcc
     6121 taaagacaaa actgtgaaga ataacttccc aataaaatca tagacatgtg cctgtccatt
     6181 aaatgattct tgaagtaacg gaagactcaa tccgagataa cgttgtgttt gcaaaatcaa
     6241 tgctgctgcc acaactacag ccccacctat cgtatttcgc caaacaggat gaggaatcca
     6301 ttgtgcatac cgtgctttta aaaagacgat cgaacggctg aatacccagc caatcaaacc
     6361 aaaagcaatc ccagcaacaa aaactttgaa gaacagcaac atactccatt cagggatcac
     6421 acccatttgg taatgtaggt gagaaacacc atagctttcc gtcatgaaat ttgcaaacag
     6481 tgcagcaaag aagctaggga agatcgcttc tgttcggact ttcccgattg ccaacacttc
     6541 taatccaaat aatgttccag ctaaaggtgt gccaaataca gaactaaaac ccgcactgat
     6601 tccactgata atcaagattt cccgttctgc tttatccaat cggaacaaac gtgctgtatt
     6661 atctgctaac gctcccccca tttggactgc tgttccttca cggccaacag atcccccaaa
     6721 taaatgggta gttatggttc caaacagtgt aagtggaata agccgcaacg ggattttttc
     6781 ttctccacca tttccttgat cgatcactaa gttgtttcca cgactagaaa gtccgccgtg
     6841 atacgcatag agataagcaa aaagcgcacc actaactggt agtagataaa ggagccaagg
     6901 atgtgatagt cggatatctg tcacaactgt caagctattt aagaaaaaag cagacaagct
     6961 ccccatgaat ataccgagaa tcgctgtgat caccagccac ttcagcatgt acactaaaat
     7021 gcgtactgga ctcggtaatt gtttttccat aaaaaattcc tcctcaataa aaaaacgcct
     7081 actaaagaaa ggggctatcc ccagacttta gtaggcgtca ttagctatct ttcgttagca
     7141 tttaaaggcg aacaccatca cctattcact tccattaaaa gatagcatat ttttctgtaa
     7201 aaaacaataa aattatcgtt ctttctttac acgttcagca aattcataga aaggagccaa
     7261 tttcgttaac tgttgattac attggtcact atcatgacaa atataattcc cctttttcgt
     7321 atacgtgcca tcagaacctg ctttcgttgt agaaagaaaa agcgaaacat tcgatgtttt
     7381 ctgacagatt gcacagattc ccttatttat cgttggtgat aaagtaccgc taatcccttt
     7441 taatttttca tcttcgtaat agaccatgaa ttttttctgc gtacctggat cattccagcc
     7501 gatgtacgta tgttcttgca agtcgatttc attccaagct ggttgtttga gttttttcac
     7561 ttttcggaat aatttctcga tttgtggttt gctaggctgc ataaacggct gaacgatttg
     7621 cttcagctcc tccaatgctc tttctgcttg cgcttttgtc agttttacgt ctaaaactgt
     7681 cgttaaaaat gtatcgattt ctggcagttc gtgatctaat atgtctcgaa tcttttcagc
     7741 tgctagtgcc tgaactgttt gcaccgtttt tggatcattg acagatgagt acgcatttaa
     7801 taactgttct acttctcttt ttataaaaaa atattggtat ggttttattg tttgttccat
     7861 gattttaaag tcctttcttc taaccaaagt gcatactttg tagaaaaaag tgatcttctg
     7921 caaagtatgt gttacctgaa gatcccggac tcttttaaat aagatacgtt ttgcatctta
     7981 tcatcacccc ctttaatgct tattcttcta tgtacatgat tcattcgata aataaaagta
     8041 aaccgtatct tgaacagata gtcaactgca aacagaaaaa aggactgtga caaaagtcgt
     8101 gtcaaagtcc cttgtttcga atgaatggtg ttcaaaagct tgcatctgcg gtaataagcc
     8161 gaaacttcac aaaaatttga gaagtaattt tcgtaaattc cttcttattt cttgaagctg
     8221 accacttctg tcacaacctc aatatggtct attattggtt ttacctgtta aatcgaggat
     8281 tctttcccaa agtaacgttg ccatctctta cgcatacttg cagacatggg ctgtgccgct
     8341 tctttgactg cgcagtattt gtccacgaat gtcacgatat atccttcttt atacttaggc
     8401 ggtgcgatcg ttgcacccca catgtgcttc aaaatgatat ctcgctcaag atccgacaaa
     8461 tcggtgattt tttctgcatt ctttacagca attcttggat ggatatacgc atgtgtcccc
     8521 tcgtcaaatt tcgtcgtacg ccaatcatag tagaacagat catgcaaaag tccagcacgc
     8581 gctgttgctt tagcattgcc accccatttt tttgcgagca gataactata gtaagaaaca
     8641 ctgatggaat gctccaaacg agtggaatga acatgctgtg tgtaattcgc taattttttc
     8701 actgcttctg tttctaaaag atcttgtaca taagacatat attcttcgtc ttcacgccat
     8761 ttttctgtca taattatcga tctgccacct ttttgaattt cattttcttc tgaaattgat
     8821 ctaagtatac caccagtgtt cggattattc tagtcgctct agataaaata gctaaagctt
     8881 aatagttcct taatcataaa gaaaaatgat aaagaacgat ccctgctgcg actccgacat
     8941 tcaatgattc cgcattttct ttcattggga tatatacgtt ctgatcagtc aaagacaaga
     9001 tttcctgact tactccctga ccttcgtttc ccatgattat agcgaaatcc tctgtttttt
     9061 ctactttgtc taatgcatgt gcttcttcat ttaattctgt accgtacacc ataaaccctt
     9121 tgcctttcat tacagggatc acttctgcca aatctttttg taacacaggc aaatgataat
     9181 tgcttccctg catgcttcgc agcacctttg tactataaat atctgccgtt cctttaccta
     9241 ataaaacacc agccatacca aacgcatctg ccgtacggat catcgttccc acatttccag
     9301 gatcctgtac attatctagt aaaagccagc ctcctgaaaa atctggcgta tcttcagatg
     9361 ttaacgccat cactgctaag atcccttgcg gtgtaggtag atctgacata gcggtcatga
     9421 cctcatctga aactagaaaa gtagaaatct ctttgtttac agccagccag tctccccatt
     9481 ctttcatacc tctctgtgtc acaaaaagtt cttttatttc tgcatcagac gacgcagctt
     9541 cttcgatcag atggaaccct tccaaaagat attctgcctt ttcttctctg tatttctttt
     9601 tatgtagttt ttttaattct ttgattcttg gattttttgc tgattggatc tctttcacat
     9661 tccttcacct cacctgatta tatcatggaa taggtgcttg agcttgtttc atcctaaaaa
     9721 aatcggtatc attgatttat aaaacaggaa agaaaggtga cgaacatgcg caaagttaaa
     9781 atgaatgtcc aaggacgtgt ccagggcgtg ggatttcgct atatgaccaa gatggttgct
     9841 gatcagttag gcgtgaccgg aacggtaaaa aacgaagagg acggctcagt cacaatcgaa
     9901 gcaatcggaa atgacgacat catccaaaaa tttatcgaag aagtcaagaa gtctccgagc
     9961 ccaagtggac gagtgcagta tgtggatgtc caagaagatc cgatgattga ggaacgaaag
    10021 aaatttgatg tggtgggata aggttgtgaa aaggtcgctt agttttgagt attaaggaaa
    10081 attttgtgaa aatgtctttc cacatttttg cataaatttg acttaatacc gagaaactga
    10141 cttttgaaca ccgtcgataa ggttgttttt gaagcgcttt gcctcgagta ttaaggagaa
    10201 acattttcaa aatagcttct catattttga aatgtaatga cttaataccg agaggcagct
    10261 gataaaacac cgtcaataag gttgtgaaaa agctggtctg catcaagcat taaggactgg
    10321 ttgtgaaaaa tagctctcca tatttttcaa caggctggac ttaatgccgt agatgcaagc
    10381 ttttgaacac catcgataag gttgtttttg aggcactttg cctcaagtat taaagacagg
    10441 tagtaaaaaa gctgatctat aacttgcaat gaatttgctt aacccatatt ttccagacag
    10501 aacaaaaaag tttttagttt tttaaataag aaagaaacac ttggaatcac tcttttcttt
    10561 ctaagtattt ctttcttgat tttttgtctt ttttcaaaat ttttcgctac gaaaaagaaa
    10621 gaatatttat atgaaatttc tatgaagttg attgaattcc atgcgctttt ttagtatagt
    10681 taagtttgtg taaaaattat agaagaggaa gtattctatg aataaatgga aaaactggtt
    10741 attgggatcc ggacttgtca gtatcctgct ctttttatct ggctgcgtgc ggatggattc
    10801 aaacggaaac cctgacactt caggaatcgt ttatcgagta ctcgtccatc ctatgggcca
    10861 agcgattaca tatctagttg agaatttcaa ttggtcttac ggctgggcag ttattgcaat
    10921 gactgtgatc gttcgtatca tcatcttgcc actaggtatc agtcaatcga aaaaaacaat
    10981 gatccaatct gaaaaaatgc aagcgttaaa accacaagtt gaagcagcac agcaaaagct
    11041 aaaagctgca acaacacgtg aagaacaaat ggcagcacaa gcagaaatgc agcaagtata
    11101 tcgcgaaaac ggattgagta tgaccggcgg aatcggctgt ctgcctctat tgatccaaat
    11161 gccgatcttc tctgccttgt attttacggc tcgctacaca gaaggtatcc gtgaatcatc
    11221 tttttacggc atcgatctag gctcaccaag tatggtgctt gttgccattg caggggtcgc
    11281 ttatctgctt caaggatata tttcaacaat cggtattcct gaagaacaga aaaagacgat
    11341 gcgtacgatg ctgatcgtct ctcctgctat gatcgtcttc atgtcgatca gtgcgccagc
    11401 cggtgttaca ctttactggg tagtcggtgg tgtgttcagc tgtctgcaaa cattcatcac
    11461 aaacgttatg atgaaaccac gtttgaaagc acaagtggca gaagagttga aacaaaaccc
    11521 gccaaaacaa gtcgtcactc caagaaaaga cgtgacagaa tcagcaaagc cagctaacaa
    11581 caaacaagca acaaaacaaa tcaaacaacc aaaaaacagt acaaacaaca aaggccgcaa
    11641 cgcaggaaag cagcagaagc ggaagtagat agtaaataag agtgtaataa aaattcatta
    11701 acagttttag caattaaaaa tatcgaccaa gatttttgaa aaagaaatct ggtcgatatt
    11761 tttatttaag tgaatgttta atttgaatca tcgattgatc gctatctaat tgcagcagca
    11821 tctttttatg aagaaacaac tttttcttat ctatcaacgt agacaggtgt tgctgtttct
    11881 tctaatagtg tacttaattc cttaatattt tgttttcctt cttctaacat ccaactactc
    11941 gctttttctt cgccttcggt aacaaaaggc gccactccct tcgcccatgt tgctcgccca
    12001 cataagacac cattgaatgt cgaacctgat tgttttgcaa aacgtaatgt atcttgaaat
    12061 agcgtagcat tgactcccgc acttaaaaaa ataaacggtt gttcagtcac tttcgattgt
    12121 tcatagaaat acgcggatgc ctctgcttga ctataacaag tctcttgccc atatccttcc
    12181 acaaatctca tattcactgg cacttctact ttcaatacat ccacttgata acgttctttt
    12241 gaaaattctc gcatggcttc aataacttta tgtggtttta cttttgcata ggcaagagaa
    12301 gacggatcgc caatagttgc atcataagag aggatctcta aaaagaaagg tatgccttct
    12361 gcttcgcatt ctgaaccaat ccgttctata actatttgtt tttgcacatt aatctctgct
    12421 ggttcatcaa cgtcatagta caataaaaat ttacaagcat ccgcaccagc ttcttttaac
    12481 cttttcaccg accaaatatt caataaatca ggtaatcttc ccggaatttt cgtatcatag
    12541 ccggtttttt cataagctag cagcaagcca cattctttct ctcgaagcgc tgctgcaggc
    12601 aggccgtatt ctggatcaag taaaatagct gaggcatagg gagtcaggta ttgagaaacc
    12661 atctgtttaa attggatgat gtcttctgat gtagcttctt tatattggtt gatcattttc
    12721 ttcaaagcac cacgctggtc gattgctaac gcgctaataa ttccagcttc atccgtcaat
    12781 cgcttcaaac gttcctgctt ttctatactc atcttcttca tagatcttca cctatttctt
    12841 tagttaatat tgtggctatt tttgtttttg attttgcttt tctcaactgt tctgtaacct
    12901 cttttcgcat caatgatcgt gcaacgagag acaataattt caaatgagtc gttcctgctt
    12961 ctgaatctgg aataaataac gcaaaaataa aatcaactga ctgtctatct aaactgttcc
    13021 attcaattcc tttgttcagt gtgacgataa tcatactagg ttcgttgatt gtttgagact
    13081 tcgcatgagg aatagcaaaa cctgacatta ttcctgtagt accttctttt tctctttcta
    13141 gaagtttttg atatacatct ttttcgtcat gagcaattcc taagcagaat gtttgctttg
    13201 ctaaaaactt aaatgcttct tcttgactat ccaatggctg ttgtaaaaaa atgttctctt
    13261 catgaatgat tgtcatgata agtctcctgc tcttcctttt tcgataactg tacgatttgc
    13321 tgctttacta tcatccatct tcttgtcttt atcagttact cttttctttt ggattaatcc
    13381 tagtatcact ccaccaacga tcgaaccaat aagaatcgct gtaacccatt ggatttttcc
    13441 tgttactaca ggtaatacta aaaaaccgcc atgtggtgct ggaacttgga cgccaaacaa
    13501 ataagtcaag acagcagcaa ttgatgagcc taacatcatc gtgggtaaca ctcggatcgg
    13561 gtctttcgca gcaaacggaa tagctccttc cgtaatatga gttgatccta aaataaaatt
    13621 aaccaaacct gcattacgat cattggtatc aaaatattta ccaaacaata aagtagcaaa
    13681 accagtaatc aacggtggcg caatacaagc tgctgacaca ccagccataa aagtcgtgtt
    13741 tccttgtgcc aaaagagctg ttcctgttac atatgccgcc ttattaaccg gtcctcccat
    13801 atcaaacgca cacatgcagc caacaatcac gccaagaaca agtggattcg aatgttcaaa
    13861 tccagctaaa aagctcatca ttccttcatt tatagccttc attggacctg ccagcaaaga
    13921 catcacgatg ccaataaatg ctacgccaat aactggatat aagaagattg ccttcaagcc
    13981 atctagttgt ttaggtaaaa ttgtcagtag cttttgcaaa aataagataa aataacctgc
    14041 taagaaccca gctaaaatac ctcctaaaaa tccagtaccg ccattcatgg ctacgattcc
    14101 accaacaaat ccaacgatta accctggacg tttcgcgatc ccttctgcaa tataagctgc
    14161 taaaactgga accatcattc ccattgatgc atcgccaact gcttttacca ttgccgctgt
    14221 agcattgtat tgtgcatgat ctggatcaaa agaatagatt ccccaaacgg caaatgaaat
    14281 agcaatcaat actccgccag ctaccacgaa aggcaacata tgagagacac cgttcatcaa
    14341 atttttatag atgctacgac caaaattagc accactcatc gcttctggtt ctaaagtatc
    14401 agcagcttca ttatctgcta agacagtacc ttttcctgcc aatgcttcgt caatcagccg
    14461 ttgtgcatcc ttgattcctg tactgacaga aacatcaatg actcgttttc ccgcaaatct
    14521 ttctgaatgg acatctttgt ctgcggcaat aatgacagca tctgcctgtt tgatttcttc
    14581 agccgttaat tcattttcga tcccaatttg tccatgggtc tctactttga tcgtgatgcc
    14641 ttttttccta gctgcttgtt ctaatgcctc ttgcgccatg taggtatgcg caattcctgt
    14701 cggacaaccg gttgctgcaa ttagttgata ttttcccatc tttcgaacct ctcttccctg
    14761 attttgattt gtttacttaa ttcctccaca tctaaaaaat ctgttaatcc tttgcgaaaa
    14821 gcggttgagc tgcctgctgc tatgctttta cgtaacgttt catcaagcgg tcgtcgattc
    14881 atgtatcctg ctaaaaaagc gcctaacatg gtatcacctg cacatgctgt attgacaact
    14941 tttccttttg gcgagtttcc tcgaaacacc ctgtctttcg taaaaagaat tgctcctttc
    15001 tcaccgaggg ataacaaaac attttctgca cctaactcta ctagtcgttg tccataaaca
    15061 aagtaatctt catctgtaac catttttcgt ccgaaccaag aagaaagttc ttcctcgttc
    15121 ggtttcagca aaaatggtcg atagggtaaa caatccatgg cttcttgatc actactatca
    15181 ataatcaaat gaatcccctt ttcctgacaa atccgactga tttctattaa aacctttgga
    15241 gacagccctc ttggtaaact cccagaaaca caaagataat cttctgcttg taatgctctt
    15301 atttgattta aaaaattatg gacagctgtc tgcggtattt caggtccttg attcactaat
    15361 ttgtattctt ctcccgtttg attgacttgt gtaaatacat tgatacgcgt cataccaggc
    15421 acttcaataa actctgtttg gatttgtttc tgctgtaaat agtcttctat atactttcct
    15481 gtgaacccag cagaaaaacc taatgccgta cttgggaaat ctagcatctt taatactagt
    15541 gacacattca ctccttttcc gtttgcctga atgtcatcct cttttgtgcg gtttaccata
    15601 aaaggatgca tctcctctgt ttcaataaat agatcaattg ccaaattcat cgtgcatgtg
    15661 tagatagaca taaccaatga cctccttgac tctattatga aatacgcgaa agagaaaatg
    15721 ttttcttaat cgttccaaca caaagaaaac ctttacattt ataaactcgt cgtgctattt
    15781 tttaactaac ttttggtgaa agaaggaaag aatatggatc acaaattaag tgaaacagaa
    15841 cagtacctct ggaactttat cgaacaccat atcctagaga tccctaacta ctccatcgtg
    15901 aaactaagtg aacaagcaaa tgtctcaaca gccaccattg tgcggacaat gaaaaagaaa
    15961 ggctatgaag ggtttacttc gtttaagcat catctaaaag aaggagaaaa caagaacatc
    16021 aatttttctt tcttagataa agtagacaaa ggtatccgcc gagccattct aaaaaatgaa
    16081 caagaagtgg tacgtacgat caatgtgttg gaaatcggaa atattgagga tgcgatacaa
    16141 agaatcaaat ttgctgaccg ggtttttgtc tttgcccgag gattttcaga aatgattggc
    16201 caagaaatgc tggtaaaact tcaattaacg ggaaaaaatt gtcaaatgca tactgatcca
    16261 gaaattatca aaagcatcag tcagaaactg actaagaaag acagcgttat ttttgtttct
    16321 ttgaacggcg agacaaaaga actcgtcacc gccgcaaaga attgctatga tgcagagatt
    16381 ggttcgattc tagttacagc caatcattcc tctacactga aagactattg cgagatcaat
    16441 ctcgtaggtt tcaaatcaga aggttcttat ttccctgatt atgaagtacg gtcacgcttg
    16501 cctctccaga ttatcgcgag aattctgctt gacgcctatg tattgcgtat gggggagaat
    16561 tgagaagcag tttattatgg ttggttacag tttaaaacat cacatttttt attctttata
    16621 ttgtatagac tcacgtaaac tttttatgta taaagttatt cacaatctat aaagttactt
    16681 taagtaacaa aaaataattg aaaatactta aaatcaaaaa atatcttttt aatcaataaa
    16741 aaaattgaca gttttattaa taataagcta ttctgttata gaagaaaaaa ttgtttgtta
    16801 ttattagcaa caaaaaaagg agtgcatcat gaaaaagtta tctcaaaaac gtttagctca
    16861 aatcattatt gattctagaa aatctctgaa aatgacacaa caacaacttg cagtagctac
    16921 tggtatcaac cgtgccttaa ttagtcgatt agaatctctc gattttatcc cgtcaataca
    16981 acaattagaa tcattagcag aagttctaaa ttttgaacca acagatctat ttataaatga
    17041 atcaaataaa tcaaacagaa caaaacatca gtcgaagaat attgctgtag ccggtactgg
    17101 ttacgtaggt ctttccattg ctactcttct tgcccagcac aatcaggtaa cagcagtaga
    17161 cattcttcct gaaaaagtaa aacaaattaa caataagaaa tctccaatac aagacgatta
    17221 cattgaaaaa tatctagctg aaaaaaatct taatttaatt gcaacgactg atggtgcagc
    17281 cgcctataga gaagccgatt ttgttgtcat tgctgctcca acaaattatg atagtaaaca
    17341 aaattatttt gatacttctg ctgtagagtc agtaatcaaa ttggtgttag aagtcaatcc
    17401 aaaggcaata atggtcatca agtcgacggt acccgtaggc tataccgaaa gtattcgtaa
    17461 aaaatacaat actaaaaata ttctattcag cccagaattt ctcagagaat ctaaggcatt
    17521 atatgacaat ctatatcctt cgcgaattat tgtcggcacg gaccaaactg acaaaacttt
    17581 acgagaagcc tctcacactt ttgcagattt actccaagaa ggagcaatca aaaaagatat
    17641 cgaaactctt ttcatgggat tcacagaagc tgaagcagtt aaattattcg ctaatactta
    17701 ccttgcactt cgagtatctt acttcaatga gctggatact tatgcagaaa tgaaaggact
    17761 aaatacacaa gaaatcattc acggggtttg cttagatcca agaattggca cacattataa
    17821 taatccatct tttggatatg gaggctattg tttaccgaaa gatacaaaac aacttctcac
    17881 taactataac gatgttcctc agaatatgat aagtgcaatt gtcgatagta atcgtacaag
    17941 aaaagacttt atagcagatc gagtgttaga acttgctggc acgtatgagg ctaacagttc
    18001 gtggaatgca gaaaaagaaa aagaggtagt cataggtgta taccgtctta caatgaagag
    18061 taattcagac aacttccgtc agtcatctat tcaaggagtt atgaagcgaa ttaaagcaaa
    18121 gggggcaact attgtaattt atgaaccaac acttgaaaat aacactacat tttttggttc
    18181 aaaagtaata aataatttag atgattttaa aaatatcagt cacagtatta ttgctaatcg
    18241 ttacgatagt aatcttgatg atgtaaaaga aaaagtatat accagagatt tatttcaacg
    18301 agattaaaaa ataacacctc agatttgtag tgtctgaggt gtttctataa acttttataa
    18361 gtaaaaaaat acaattatac ttcataaaaa gacttatacc actgcgcaaa tttacgaagc
    18421 ccgtcacgca aacttgtact tggtttaaat tcaaaatctc gttctaacgc actagtatct
    18481 gcataagtaa ctggcacatc tcctggttgc attggaacta gttcggtatg agattcaaag
    18541 tcgtaatctt ctggtagcac ccctgctgca attagctctt gttgtagaat atctacaaaa
    18601 tctagtaggt tttccggcgt attgttacca atattataaa tatgatatgg tgggattggt
    18661 agcccatctt ccccatcaat tttctctgga gcgcactgca taaccctctt tactccttca
    18721 acaatatcat ctatataggt aaagtcacgc ttgcaattcc cataattgaa tatttggata
    18781 ttatcaccag cacgaagttt atcagtaaaa ccaaaataag ccatatctgg acgcccagca
    18841 ggaccatata ctgtaaagaa acgtaaccct gtagacggaa tattgtaaag tttagaatat
    18901 gcatgtgcca ttgattcatt acttttctta gttgctgcat acaacgatac ttgattgtct
    18961 actttatcct ctgtagaata aggaattttc ttattagtac cataaacgga agacgatgag
    19021 gcatacacta aatgttccac accagattct ccattatcat atgaatgacg acaagcttca
    19081 agaatattat agaatcctat tatgttagat tcgatataca tatctggatt agtaattgaa
    19141 taacggactc ctgcctgagc tgctaaattc accacgatac ttggtttata attatcaaag
    19201 atgaaatcaa ttgttgcttt atcagcaata gaacctttga taaaattcca agtagatcct
    19261 ggatggttct ttgcctccgt ttctatctct gataatctat agttcttaat agagacatca
    19321 tagtaatcat tcatattgtc aatgccaatg atttttattg atgactgagt acgtaataac
    19381 tcaagaacca aatttgatcc aataaaaccg gctgcgccag ttattaatat tgttctattt
    19441 gataaggacg tgtttaattc cagcattttt tagcactcac tttctttttt tcttatgaat
    19501 acatatttgt tatatattaa aaaatcttat ttagacttat ctattgtcac ttttatcatt
    19561 ctaatctttg cacgtagtag aataattata cagataggaa attgctaagc aacccacttc
    19621 tttctattat ctattaactt attctaaa
//
LOCUS       DAZKCW010000046        19480 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000046 DAZKCW010000000
VERSION     DAZKCW010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.046"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            133..3660
                     /locus_tag="ACG84Z_001949"
     CDS             133..3660
                     /locus_tag="ACG84Z_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFP9162762.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="ACG84Z_001950"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="ACG84Z_001950"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFP9162763.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="ACG84Z_001951"
     CDS             7448..7789
                     /locus_tag="ACG84Z_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFP9162764.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="ACG84Z_001952"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="ACG84Z_001952"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFP9162765.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /gene="pheT"
                     /locus_tag="ACG84Z_001953"
     CDS             9146..11566
                     /gene="pheT"
                     /locus_tag="ACG84Z_001953"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFP9162766.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACG84Z_001954"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACG84Z_001954"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFP9162767.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="ACG84Z_001955"
     CDS             13000..13737
                     /locus_tag="ACG84Z_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFP9162768.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="ACG84Z_001956"
     CDS             13751..14566
                     /locus_tag="ACG84Z_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFP9162769.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="ACG84Z_001957"
     CDS             14579..15226
                     /locus_tag="ACG84Z_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFP9162770.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="ACG84Z_001958"
     CDS             15242..15898
                     /locus_tag="ACG84Z_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFP9162771.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="ACG84Z_001959"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="ACG84Z_001959"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFP9162772.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="ACG84Z_001960"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="ACG84Z_001960"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFP9162773.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="ACG84Z_001961"
     CDS             18240..18758
                     /locus_tag="ACG84Z_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFP9162774.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /gene="cbpB"
                     /locus_tag="ACG84Z_001962"
     CDS             18865..19365
                     /gene="cbpB"
                     /locus_tag="ACG84Z_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFP9162775.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
BASE COUNT         6551 a         3344 c         4182 g         5403 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg tgcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag
//
LOCUS       DAZKCW010000047        18535 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000047 DAZKCW010000000
VERSION     DAZKCW010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.047"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            130..777
                     /locus_tag="ACG84Z_001963"
     CDS             130..777
                     /locus_tag="ACG84Z_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFP9162776.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    906..1122
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1170..3815
                     /locus_tag="ACG84Z_001964"
     CDS             1170..3815
                     /locus_tag="ACG84Z_001964"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFP9162777.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4125..5438
                     /locus_tag="ACG84Z_001965"
     CDS             4125..5438
                     /locus_tag="ACG84Z_001965"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFP9162778.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5428..6081
                     /locus_tag="ACG84Z_001966"
     CDS             5428..6081
                     /locus_tag="ACG84Z_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9162779.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6136..6828
                     /gene="radC"
                     /locus_tag="ACG84Z_001967"
     CDS             6136..6828
                     /gene="radC"
                     /locus_tag="ACG84Z_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFP9162780.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6978..7178
                     /locus_tag="ACG84Z_001968"
     CDS             6978..7178
                     /locus_tag="ACG84Z_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9162781.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7432..9111)
                     /locus_tag="ACG84Z_001969"
     CDS             complement(7432..9111)
                     /locus_tag="ACG84Z_001969"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFP9162782.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9113..9325)
                     /locus_tag="ACG84Z_001970"
     CDS             complement(9113..9325)
                     /locus_tag="ACG84Z_001970"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFP9162783.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9718..11448
                     /gene="efrA"
                     /locus_tag="ACG84Z_001971"
     CDS             9718..11448
                     /gene="efrA"
                     /locus_tag="ACG84Z_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFP9162784.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11445..13205
                     /gene="efrB"
                     /locus_tag="ACG84Z_001972"
     CDS             11445..13205
                     /gene="efrB"
                     /locus_tag="ACG84Z_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFP9162785.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13300..13497
                     /locus_tag="ACG84Z_001973"
     CDS             13300..13497
                     /locus_tag="ACG84Z_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162786.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13650..14135
                     /locus_tag="ACG84Z_001974"
     CDS             13650..14135
                     /locus_tag="ACG84Z_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFP9162787.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14239..14832)
                     /gene="clpP"
                     /locus_tag="ACG84Z_001975"
     CDS             complement(14239..14832)
                     /gene="clpP"
                     /locus_tag="ACG84Z_001975"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFP9162788.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            15012..15533
                     /locus_tag="ACG84Z_001976"
     CDS             15012..15533
                     /locus_tag="ACG84Z_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162789.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDV"
     gene            15630..16367
                     /locus_tag="ACG84Z_001977"
     CDS             15630..16367
                     /locus_tag="ACG84Z_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFP9162790.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16371..17288
                     /gene="miaA"
                     /locus_tag="ACG84Z_001978"
     CDS             16371..17288
                     /gene="miaA"
                     /locus_tag="ACG84Z_001978"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFP9162791.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17290..18519
                     /gene="hflX"
                     /locus_tag="ACG84Z_001979"
     CDS             17290..18519
                     /gene="hflX"
                     /locus_tag="ACG84Z_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFP9162792.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEIAVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5992 a         3208 c         4028 g         5307 t
ORIGIN      
        1 accgcagatg caagcttttg aacaccgttt tatttgtctc acaccctttt ccttcctact
       61 tgtaaccttg ctcccgtgtt agaaacatgt tacactaaat atgtgaaatt attaacaagg
      121 agcgtcgtta tgcgagaaaa aacagataca ctgccaaaag caactgcgaa aagattacct
      181 ttatatttac gctacttgaa gatgctggat gactcaggta taagtagaat caaatcaaat
      241 gagttcagcg aaatcaccca aattccttct gcaacgatcc gcagagactt ctcgcaatta
      301 ggcgagctag gcagaagcgg atatggctat gatgtccctt ttcttatcga tgtattcaat
      361 aatatcctta atactaaaga agaaaaacga atcgcattag taggatatgg aaatcttggc
      421 aaagcattga aacacaacaa ttttagaaga aatgaaaatc taaatatcgt gtgcgtcttt
      481 gataatgatc cagcactgat caatcgagta attgatggag aaatgatcta tccgattgat
      541 cgtttcgcgg agatagccaa agcaaaaaat gtgacagtag caatctctac ggtaccaagt
      601 aaatattcac aatctgctat tgatgaaatt gtcaaaggaa atgtaaccgc tatacttaat
      661 tttgcgcctg acagagtaac tgtcccagct tatgtcaatg ttcaatacat tgatttgaca
      721 accgagttgc agacgcttat ttactttgat gagaattact cagaagtttt ttcttaggaa
      781 aatttgagta ggcttattga tcttgcgaga actcgtcgta attctttcaa aaatttttta
      841 gtactaaatg aagtggtttt ttcacgacca cttgttgact aaaaaaaaaa accattgtag
      901 aatgaagcat aacgctgaac aagaggagta actggcacat tcattcttag agagagaact
      961 atctgctgaa aggttctcaa tgacaaccag tgaaggtagc ttgggagttt ctgtcttgaa
     1021 tggagtagag atagacgagt cgtgatcgtt aactcacttg agaggcaata atgattgatt
     1081 attgcaattt aggtggtacc gcgtaaatca tacgtcctag aatacgaaag tattttagga
     1141 cgttttttag tttaaaggag gaaaacagca tgacggaaga aaataaccta tcaacaaaat
     1201 ataatccgca agaagttgaa gctggacgtt atcagcattg gttagaacaa gatttgttta
     1261 aaccgagcgg agataaaaaa gcaaaacctt attcaatcgt aatcccgccc ccaaatgtta
     1321 ctggaaaact tcatttaggg catgcttggg atacgacctt gcaagatatg ctgattcgtc
     1381 aaaagagaat gcaaggatat gatactttat ggctgcctgg tatggaccat gcaggaatcg
     1441 cgacacaagc aaaagtagaa gcgaagctta gagagcaagg gatttctcgt tatgatctag
     1501 gtcgtgaaaa gttcatcgat caagtgtggg aatggaaaga agagtatgcg agccacatcc
     1561 gcgaacagtg ggctaaaatg ggcttatctt tagattacag tagggaacgt tttacattag
     1621 atgatggatt atctgaagca gtacgtaaag tttttgttac cttatacgaa aaaggtttga
     1681 tttatcgtgg tgaatatatc atcaactggg atcctcaagc acgaacagct ctatctgata
     1741 tcgaagttat tcataaagat atcgaaggcg ccttttatca tatgagctat gaactagcag
     1801 atggatcagg cgtagtagaa attgcgacaa cccgtccaga aacgatgttg ggagatacgg
     1861 cgattgctgt tcatccagaa gacgagcgtt atcaagcgct catcggcaaa aaagtgattc
     1921 tacctttagt caataaacaa atcccaatca ttgcagatga atatgtagat atggaattcg
     1981 ggacaggtgt agtaaaaatc actccagcac atgatccaaa cgactttgag gtaggtaatc
     2041 gtcatgatct tccacgcgta aatgttatgg atgatgatgg tacgatgaat gaactagcag
     2101 gaaaatatgc tggaatggaa cgttttgctg ctcgtaaagc aatcgtgcaa gatctgaaag
     2161 aaatcggtcg attgattaaa atcgatacga tgatccacag tgtgggtcat tccgagcgga
     2221 caggtgtcgt tgttgaacct cggctgtcta ctcaatggtt tgtaaaaatg gcgccgttag
     2281 cgaaaaaagc cattgataac caagaaacag atcaagcagt ggaattcttc cctccaagat
     2341 tcaatcaaac gtttttacgt tggatggaaa atgtccatga ttgggtaatc tcacgacaat
     2401 tatggtgggg acatcaaatt cctgcatggt atcacaaaga aacaggtgaa atgtatgtag
     2461 ggatggaagc accagcggat agtgaaaact gggtacaaga tcctgatgtt ttagacactt
     2521 ggtttagttc agctttgtgg cctttctcaa caatgggctg gccagatacg gaaagcgaag
     2581 attataagcg atacttccct actagcactt tagtaaccgg ttatgacatc attttcttct
     2641 gggtaagcag aatgattttc caaagcttgg aatttactgg cgaacgtcca tttgagaatg
     2701 tcttgattca tggattgatt cgtgacgaac aagggcggaa gatgagtaaa tcattaggta
     2761 atggaatcga tccgatggaa gtaatcgaaa agtatggagc agatgctctc cgctggttct
     2821 tatcgaatgg ttctgcacca ggacaagatg tccgcttcag ctatgaaaaa atggatgctt
     2881 cttggaactt tatcaacaaa atctggaatg cttcacgttt cgttatcatg aatatcgaag
     2941 gaatgaccgt agaagagatc gatttatctg gagaaaaatc agtggctgac cggtggatcc
     3001 ttactcgttt gaatgaaacg atcgaacgag taactgagct atttgatcgt tttgaatttg
     3061 gtgaagcagg tcgacaactg tataacttta tctgggatga tttttgtgac tggtacatcg
     3121 aaatgagtaa agaagtactt tatggagatg atgctgtttc aaaacaaacc acccgtagca
     3181 tcttagtcca tacacttgat cagatcctac gtttattgca tccaatcatg ccattcgtta
     3241 cagaagaaat atgggaacat attcctcatc agggaaattc tctagtagtg gcagaatatc
     3301 ctgttgtacg tccagagttt gatgatgaaa cagcttctaa agggatggaa gtattgaaag
     3361 aattgattcg agccgttcga aatattcgtt cagaagtgaa tacaccattg tctaaaccaa
     3421 ttacgttgct aattaaaaca aacgatgcta aaatcgatca atttttagtt gaaaatacaa
     3481 gctatatcga acgcttctgt aatcccgaag agttgacgat atcaagtgag atcactgcgc
     3541 cagatctagc gatgtcagct gttctgacag gtgcagaaat cttcttgccg ttagcaggat
     3601 tgatcaatat tgaagaagaa atcaaacgat tagaaaaaga actggaaaag tggacaagcg
     3661 aagtaaaacg tgtccaagga aaactttcta atgaacgttt tgtttctaac gcgccggaag
     3721 aagtagtaga ggcagagcgt gcaaaagaaa aagattattt agagaagcaa acggctgtca
     3781 aagaacgaat cgaaagtttg cgtactattc aataagaata gaaaaagaga gtgtgaaatc
     3841 agctagctat tactaaaagc tagctgattg aacatcgtta caggaaagag tttgagcctc
     3901 actcttagct tcgattcata aggagatgtg acataaattt tgtcgcatct cttttttagt
     3961 ctactcttat tatgtaggag aaggagggag gtggatcatg tatcaagagt caataaagta
     4021 gttgataaaa tcgttcctct ctctgtttct tttctctttg tcatactttt atttttctta
     4081 tgtgttctat ttgttataat aaaagagaaa tgggggaatt gttgatgacg attgaagaag
     4141 caatagaatg gatccatagt cgattaccat ttggttcacg tcctggcctt gaccgagtcg
     4201 aagctttatt agaagtggta gggcatccag agagaaaagt aaaaacgatc catatcgctg
     4261 gaacaaacgg aaaaggttct actgtagctt atttgagaag cctattagaa gaggctgggc
     4321 tgacagtagg tacatttact tcaccttata tcgaaacgtt caatgaacgg atcgcaatca
     4381 atggcaaaag cattccagac aatgatttga tccagcttgt aaaaaaatat cagccactga
     4441 tcaaacaact tgatcaattt gaagcagtag ctggtattac tgaattcgag acattaacag
     4501 caatggcatt tgattatttt ttgatgaaga aagtggacgt agcgattatc gaagttggct
     4561 taggcggctt attggattct accaatgtag ctgtaccaat gctgacggga ataacaacga
     4621 ttggacttga tcataccgaa atacttggag atacaattga agaaatcgct gcacaaaaag
     4681 ctggaatcat caaacaaggc gttccagtag taacaggaaa tattgcccca gaagctttta
     4741 ctgtcatcca acaaacagct aaagcaaaaa atgcaccgct ttatgtatac ggggaaaatt
     4801 ataaaataaa ctatctgcat cctgatgaga tgtggggaga agtatttgaa ttttttaatg
     4861 aaataggaaa gatccctcaa ttaaccactc cgcttttagg gcaacatcaa gctgaaaatg
     4921 caggagtagc catcgaattg tattttgttt actgtcaatt ggaaaagctg cctttccgag
     4981 aaaaagatgt tttgaaggga ttgaagaaat ctcgatggcc aggaagaatg gagcgtttga
     5041 gtaacgagcc attagttgtt ttagatggtg cccataatac gcatgcaatg aaccggcttg
     5101 ttgagaattt gaaaaaagaa ttcaaaggat atcaaatcaa cattttgttt tccgccttac
     5161 gaactaaaaa tgttagagaa atgctagaac gattgcagca agtaccaaat gtccatattt
     5221 atttgacgac ctttgaacat ccaaaagcca tcgaattaag tgaagtatca gatttagcaa
     5281 gtgagagagt atcaatcgtt tcattgtggc aattcggatt agcagatata ttggaaaaga
     5341 tgacaaatga agacgtatta gttgtgaccg gttcacttta tttcatttca gaagttcgcc
     5401 atttattaat acaattagga ggagatcatg aagtataatg cagtgatttt tgacatggat
     5461 ggtttgctgt tcgacacaga gttagtgtat tacgaagcca cacaagtagt agcagacaag
     5521 atgggttttc cttatgataa agacctgtat ttaaaattct taggtgtttc agatgaagaa
     5581 gtatgggcga attatcatat gattttctcg gaatttggca aaacaagtgt acaaagattc
     5641 atagatgatt cataccagga aacgcttgaa cgtttttcgc aaggagcggt acaaatgaag
     5701 cccggtgtgt tggaactcct ctctttttta gaagaacatc agattcccaa agttgtcgct
     5761 tccagtaacc aacgagcagt cattgaactt ttattgaaga agaacaatct gtttgaacga
     5821 tttgagacga ttgtttctgc agaaaatgtt caacgagcaa aaccagaccc agaaattttc
     5881 ttgttagcta atcagaagct aggtacagcg aagaaagaaa cattgatttt agaagattca
     5941 caaaatggta ttttagcagc ttctgcggct gagatcccgg tagtcatggt accagatctg
     6001 cttccaccat cccaagaatt gatcaaaaaa acagctgggg ttgtttcttc tttacatgaa
     6061 atccctgcat tgttaaaata aaaatccatc tcttttcgta tcttatttta gataagatag
     6121 aaaggagatg tttttttggg aaaacgattg atcaaagaag tacctactag ctctttacca
     6181 agggaacgta tggaaattta tggcgcggaa gctttatcgg atcaggagct tttggcaatc
     6241 ttactgcgta ccggtcaaca cccttatagt gtgatgtcga ttgctggaaa tctgttaaaa
     6301 acgtttggag gactggcctc tttacgacag gctactttgc atgagttaga agagattcga
     6361 gggataggac gcgtgaaagc aatcgaaatc aaagccttga tcgaattagg tcgacgaatt
     6421 cagacggatc atgaaagagc ggctccaccg gttcgtacca gctacgaatt ggcccagcaa
     6481 ttgattctgg aaatgaaaga tcacaaacaa gaacatttgg tttgtattta tttggacacg
     6541 aagaatcaag tgatcttaaa aaaaacagtg ttcatcggtt cgctgaatca gtcagtcgct
     6601 catcctagag aaattttcca ttatgctgta cgttattgtg cagcaaggat cgttttagcg
     6661 cataatcatc cttctggtaa tgttattcca tcgcagcagg atatgaattt taccaaaagg
     6721 atacaaaagt gtggagaaat gatggggatc actgtactgg accacttgat catcggacgc
     6781 aaacgatatt ttagtttgag agaagaagga atgatggaag agaagtaagt tgctttcttg
     6841 caaaaaaaat gaagcaagtg tacaattata ttgtaatttt gtttgggaat agaagttgaa
     6901 acatctgttg cacctctatc gtacacgagc aatgttacaa tttaaattag tgcttttggc
     6961 acgaggagga tattattatg gaaaacggaa cagtaaaatg gttcaacgct gaaaaaggat
     7021 ttggatttat ctcacgtgaa gatggaagcg acgtattcgt tcacttctca gctatccaag
     7081 gtgacggatt caaaacatta gaagaaggtc aagcagtgac tttcgacgtt gaagaatcag
     7141 accgcggccc acaagctgca aacgttgtaa aagcttaatt ttatctgtaa atcaaattga
     7201 tggtagacat caatttttac gagagaacaa agcgagtaac aaaaatacct gccacaagag
     7261 acaatttctc ttgtggcagg tatttttttg tatgaaaaag taaataaatt taagaggcta
     7321 tgaaagagcc accttgtatc aaggaataag aacaaacaaa aatggcttct catgtttttc
     7381 atttgttttc tcttatattc aggacaaggt gctgatttca taacctctta tttattcttc
     7441 atctggtgtc attaccattg gcaaaatcat tggatgtctt tctgtacgtt cgaataagaa
     7501 aggctgaagc gcgccagtca tcgcttcttt caatttatat tctgaacagt caggtccatt
     7561 caaacattct cttaaagcgt ggaataagat tcgctgagct tcattgatca tttctcctga
     7621 ttctcgcatg tagacaaatc cacgagagag aatatctgga ccagccaaga tttctttttt
     7681 cttgatatcc actgtcgcga cagctaatac aagaccttct tctgaaagca ggtgacggtc
     7741 acgtaaaacg acattaccaa tatcaccgat cccgctacca tcgatataca catctccagc
     7801 cacaaaatgc ccagcaggac gcgcagaatc gctagttaac gctaaaacat cgccattttc
     7861 catgatgaag cagttttctg caggaacacc tacatcttgt gctagagaag catgtacttt
     7921 caacatgcgg aattctccgt ggacaggaat aaaatatttt ggcttcatca aacgaagcat
     7981 taatttttgt tcttcttgtc caccgtgacc ggaagtatgg atgttattga tttttccgtg
     8041 aatcacttct gcaccagctt cagacagcaa attgatcaaa tgattgacac ttgttgtatt
     8101 accaggaata ggtgaacttg aaaagatcac tgtatcgtct ggctggattt ggatttgacg
     8161 gtgagtacca ttcgcgatgc ggctcaacgc ggccatcgct tctccttgag aacctgtaca
     8221 taggatcatc gtttcattgg caggcaagcg attgatttcg tgtgcatcta caaatgtgcc
     8281 gtctggaact ttgatatatc ctaaacgttg accgttgacg atggcatttt ccatgcttcg
     8341 tccgaaaaca gcgattttac gaccagttgc cacagcggca tctgctgctt gctgcaaacg
     8401 gaagatgtta gaagcaaagc tggcaaaaat gatacgtcct tcgatttttg aaaagatctt
     8461 caaaatagaa tgcccaatcg ttttttctga tttagtaaat gttggaatct cagcatttgt
     8521 actatcagat aaaaggcaca agactccttc ttccccgata cgagccattt tatgcaagtt
     8581 tgctggttcg ccaacaggag tgaaatcgaa tttgaagtct ccagtcgcta cgatatttcc
     8641 agaaggtgtt ttcaccacga tccctaatgc atctgggata ctatgggtcg ttctgaaaaa
     8701 gctgacagaa gtctttctaa aacggatgat cgtatcttca ttgatctcat ggagctctgc
     8761 atctcgaagc aagccatgct catctaattt gtttgtgatc aacgctaatg cgagaggacc
     8821 agcatagata ggaatatttg cttgtttcag caagtagggt attccgccga tgtggtcttc
     8881 gtgcccgtga gtaatcacca aggcttttac tttgtgtaag ttttgtatga tgtagctgta
     8941 gtcgggaatg acatagtcaa ttccaagtaa atcgtcttcc gggaatttga tcccggcatc
     9001 aatcaaaatg atttcatctt ggaattgtac cccatacgta tttttcccga tttcacctaa
     9061 tccaccaata gcaaagacgc ctgtctcgtt atttttgatg gaaagtttca tattaaaact
     9121 ccactaatga gaaatcagca ttttcttttt cgtactctag atgacttcct tctagaagtt
     9181 gaacgaattc aatattgtat ggggtatttt cttccacacg ttggcgagcg tctacatcgc
     9241 tttttgcctc aatgtaaaga gattttgttt cttcccgttt agggttgcgt acttttgttt
     9301 cttgataata aactttatag atcattgttt tgtctccttt atctgcgtaa agcagtgatt
     9361 tagctagttg atttttttag acaacacaaa acgaggggac aagccacctg gtttttcata
     9421 tgctttgact agaatactgg attcgagtca aagagacaag cctcgttttt gcttatctgt
     9481 tcggatattt tttcaaccgt accttctgta taaaaaatat acaacaatta attgttattc
     9541 tagcataaaa cagcaaataa gtatagaaat caactagatt gaaagaaaaa atcaatgttt
     9601 atcatcccgc tataatcata atgacttttt tatgagagaa gtgttctatt aataggctcg
     9661 ttgtgctatc atttttagta atgaaaatgt aacaaaagat taaaaggaga tgagaaagtg
     9721 aaactaatgt ggcattatac catgcgttat aagaaattct tgtttttcaa tttcatatgc
     9781 gtatttggtt ttattttgat tgaattagga cttcctacga ttttagcacg tatgatcgat
     9841 gtaggaatcc gcaatgatga ttttgattat gtgaagcaac aagggatatt tatgatcgtt
     9901 attactgtaa tcggtattat tttgaatatc ttgttaggtt attttggttc gaggattacg
     9961 actaatatcg tagcagatat tcgagatgat ttgttcgaaa agatccaaag ttattcgcat
    10021 caggaatacg aaaatctagg cgtatcttca ttgatcactc gtacaacaaa cgatgcttat
    10081 cagatcatgt tgttcctgca aaatatttta cgtatcggtt ttatggcacc aatgatgttc
    10141 attgtcagtt tgtacatggt catgcgtaca agtgtgacac tcagtttgta tgtagtaggt
    10201 gcattacctt tactattatt ggcagtcgta gcgattgcta aggtgtctga accgttatct
    10261 aaaaagcaac aaaaaaactt agataaaatc aacagtatct tgcgggaaaa tctttcagga
    10321 ttgcgtgtga ttcgtgcatt cgtcaatgaa aagtttgaag aaaaacgttt tgctgtagtc
    10381 aatgagaatt atgcttctag ttcaaaaagc ttattccgtt tgatggctgt tgcacaaccg
    10441 ggtttttatt tcttatttaa tatcgtaatg gtattgatca tctggagcgg ggcagtgcaa
    10501 atcgatgcag gcgagcttcg tgtaggagat ttgattgcgt ttatcgagta tatattccat
    10561 gccttgttct cattcatgtt atttgctagt gtgttcatga tgtatccaag agcagctgtt
    10621 tcagctggac gtatccaaga agccctagat gccaaacctt cgattgtaga agatccaaat
    10681 ggtatatctg atacaaaaac taaagggtat atcgaatttc aaaatgtaac atttgcttat
    10741 ccaggccatt cgcaagagcc agtgatacga aatgtcagtt ttacagcctc tccaggagag
    10801 accgttgctt ttattggaag taccggtagc ggaaaatcta cgttgatcca attgatccct
    10861 cgcttttatg atgtgagtga aggaaagatc ttgatcgatg gagtagacgt gagagattat
    10921 cggctaagca agttgcgaga taagattggg tttattccgc aaaaagcgct gctatttact
    10981 ggaacgattg cagataattt gcgatacggg aaagaagatg ctacgcaaga agaaatggaa
    11041 cgtgcagctg agattgctca agcttcagaa ttcatttctc gaaaaccaga tggatttaat
    11101 gaacatttat cagaaggtgg ttccaatttt tcaggtggac aaaaacaacg attggcaata
    11161 gccagagcca tcatacgccg tccggaaatc tatatttttg atgacagctt ttctgcatta
    11221 gattatcaaa cggatgcgaa gttacgtgct cgtctgaaaa aagaaacgac agaatctact
    11281 gtattgatcg tagcacaacg tgtgggaacg atcatgcatg cagataagat catcgtatta
    11341 aatgaaggag aagtcgtcgg tatggggacg catcgggagt tgttggaaaa atgcccgatt
    11401 tattatgata ttgccgcttc tcaattatca aaggaggaat tagcatgaaa aaaacctttt
    11461 cttccttaaa acgtttagct cgatatatca gaccgtatcg tgagactttt cttttagtga
    11521 tcctatttac agttctgaca gtggctttca acgtggcttt gccatatgtt acaggacttc
    11581 ctactacaga aatcagccgt aatattgcca atggcgaatc aatcaatttt tcttatatat
    11641 tcaaatgtct catttggatc acagttgttg gaatagggta ttgtatttcg caattacttt
    11701 ctggtgtttt gatgacaaat gtcgttcaaa gtgccatgca tgatttgaga agagacatag
    11761 aagaaaaaat caatcgtctt ccggtttcat atttcgataa aaaccagcaa ggaaatattt
    11821 tgtctcgtgt gacgaatgat gtagatgcag tcagcggtgc tttacaacaa gcttttattg
    11881 gtatcgtaaa tgcgatattg ggaattacgt tggctgcagc aatgatgttt tatatccagc
    11941 cgatgatggc gctgatctct atgatcatga ttccaacatc gatctggatc tcaaaacgag
    12001 tgatcaatgc ttcgcagaaa tattttcaaa gcatgcagaa ttctcttggt gagctaaacg
    12061 gctacgtcca agaaaatatg acaggtttta gtgtattgaa agtatatgga cgcgaaaaag
    12121 aaacattgga aggattcaaa aaagttaatc acagcttgaa atactttggg tttcgtgcag
    12181 cattcatttc tggcttgatg atgcctctag ttcaattaac tgcctatgct acttatattg
    12241 gtatggctgt tctaggaagc ttttatgtta ttactggggc gatcgttgtc ggtcaactac
    12301 aagcattcat ccaatatatt tggcaaatca gtcagccaat ggggaacgtg acacaattgt
    12361 cttcagtttt gcaaagtgca tcagcggcaa cgaaacgtgt attcgagatt ttagatgagc
    12421 cagaagaaaa agaaaacaaa gtagatgctt cactgccaga aacgatttta ggagatgtga
    12481 cattcgatca tgtcgatttt gcatatgatc cgaagaaacc attaatccaa gatttgaatt
    12541 ttgaagtgaa agctggtcaa accgtagctg tggtcggtcc gaccggtgcc ggcaagacga
    12601 cattgatcaa tctattgatg cgtttttatg acgtagacaa aggagcaata aggattgatg
    12661 gaatcgacac caaatcaatg agtcgcagtg atgtgcgttc gctatttggt atggtcttgc
    12721 aagatgcatg gctttatcaa ggaacgattg cagataatat ccgcttcgga aagcttgatg
    12781 cgacagatta tgaagtagtt gatgctgcga aaacagcaaa cgtagatcat tttatccgaa
    12841 cgatgccaga tggatatgat atggccatca attctgaggg agacaatgtg tctttaggac
    12901 aaaaacagtt gctgacgatt gcccgagcag tggtctccga tcctaaaatc ttgattttag
    12961 atgaagcaac aagttcagta gacacccgtt tagaagcgtt gattcaaaaa gcaatggatc
    13021 gcgtgatgga gggacggaca agtttcgtca tcgctcaccg tttatcgaca atccgtgatg
    13081 cagatctgat tctagtgatg gatcaaggtc agatcattga aaaaggaacg catgagagtt
    13141 tattggcaca aggtggattt tatgaaaaac tgtataacag ccaatttgct gaggaagcag
    13201 aataagtcat ataagaataa aacagtttaa aacttatttt ttgttctcta ttcttgataa
    13261 tggtaaagta aagttatcaa gaaaagtgag gacacggaga tggaacagtt tttaaatgaa
    13321 aaaattactg aagccaaaag agaagttgat cgtttaacgc acgtctgtca gacgaagcct
    13381 tttgattcag ctgatttttt tgaaaatgag tttcaaatcg aacgcttggc agcacaaata
    13441 gaagtgtacg aattaatttt aaaaaaagta atagaagaaa atatagatgt acaataaaaa
    13501 caggtaaaac gtcagttacc agatactgta aatagacatc tggcctgagc aggttttacc
    13561 tgtttttttt cttatgaaat aaatatatgc tatgatacct ttattcaata ggattagttt
    13621 ctacaaaaaa tgaaaggaga aaaataaata tggaacggtt tatagcatca aatgccacag
    13681 tgattggtga tgtgacattg tcagaagatg tgacgatctg gtatcaagct gttttacgcg
    13741 gggacagtaa ttggataaaa ataggacaaa gaacgaatat ccaagatggt acaatcatcc
    13801 atgtcgatca tgatgcacct gtagatattg cggagaatgt gacggtagga catcagtgca
    13861 tgctacatgg ctgtacaatc gaaaaagggg cgctgatcgg gatggggacc acgatattga
    13921 atcatgcggt tattggtgag aatagtttga ttggtgctgg atcattagta acagaaggaa
    13981 aagttattcc tcctaatgtc ttggcttttg gtcgcccagc taaagtgatc cgtcctttga
    14041 caaaagaaga aatacaaaaa aacaaagaaa acatccagca ttatgtcgag ataggtcgga
    14101 tgcatgcgca aggaaaattc aaggagcaaa gataggcagt agcatccata aaataaaaaa
    14161 ggatggtcag tttgagttga ccatcctttt ttatttggtt tagataagag agcttaaaaa
    14221 agcttccttt gaaacagatt aatttaatga agaactgttt tccatgactt catcgatcaa
    14281 tccatatgct tttgcttgtt cagctgtcat atagttgtca cgatctgtat ctttttcaat
    14341 cacttcaagc ggttgtccag tgcgttcagc taaaattttg tttaagcgtt cgcgtgtttg
    14401 caaaatatgg cgtgccgcaa tttcgatttc agttgcttgc ccttgagcgc cgccaagagg
    14461 ttgatggatc atgatctcag catttggtaa agcaaatcgt ttaccttttg taccagctgt
    14521 cagcaagaag cttcccattg aagcagccat acccataaca attgtttgga catctgcttt
    14581 gacaaagttc attgtgtcgt aaatagccat acctgctgta actgaaccac caggagaatt
    14641 gatataaaga tagatatctt tttcagaatc ttgagcgtct aagaaaagca attgggcgat
    14701 gatcgaatta gcaagatcat ctgttacttg gccgcttaac atgatgatac ggtctttcaa
    14761 taaacgtgag tagatatcgt aagctctttc acctcgtgaa gattgttcaa tgactgtagg
    14821 aattaaattc ataatagagt tcctccttga tttcgtttag aaatagtgta ccataattta
    14881 gtttctaata cctaaaatgt agtatacatt tttggtcaaa aaaggtcaaa taaaaaactt
    14941 aggcaaatta gtcgcataaa cccgctttat ggtatgataa gcagagaaac aaaacaagga
    15001 ggaacaacag attgatagtt ggtattactg gccttatcgg agtgctgaca ggtgctgtag
    15061 ttgtctatat cggcatgata ctgcaaatgc gtcacttgga aaataaagaa cagcgtagac
    15121 gtgaattgga attgaaagtc aaagaaatcg agacgctgaa tcaattaaat aaaaagatca
    15181 acgagatctt gcaaaaacgg acaacgctga tggaagaata tgtcagcttt gatgcatttg
    15241 atgattgtta tatcacgatt gacgattttg cgtatctcca atcattttca gcgcaaaata
    15301 gtttttatct gccaaattat attttagacg agctatttaa gaatatctcc catcgaaaag
    15361 tgattttatc tccagatgaa acaatgaaga ttggtggata tgcttataaa ggcggacgcg
    15421 tgattttaga gaattttacg gatagtctga ctgaaatgat caatgaaaaa aaagctcagt
    15481 tgaagactat gacgcgccag ccgattggtt tcttctcgaa agatgatgtt tgaagctgat
    15541 attttgaagc attgccgttg cacatgagag cgtggtaatg ctttcttttt ttcttaatga
    15601 tacaatagaa ctgaacggag tgaagaaaga tgttacaaat ctatgcccat cgcggaagca
    15661 gcggcaccca cccagaaaat acgcttcctg catttgcaga agctgtacga gtaggtgcag
    15721 atggtatcga actagatgtc catctaagca aagatggtta tttgatcgtt atgcacgacg
    15781 aagaagtgga ccggacgact aacggtaaag ggctgattcg agaaaaaaca ttggaagaac
    15841 tcaaaaaatt gaatgcaggg ggcaaattca gcaaagaatt tccagcagct aaagttcctg
    15901 aattgagaga agtgttagga ctgctcctcc aaaaaaatta ccgagggatg ctaatgattg
    15961 aaattaaaac tgatcagtat gaatatcccg gtatcgaaga aaaattagcc gaaacattaa
    16021 aaagtagaga ttggcctttt caacatgcat attgcagctt tcatttggat tctttggaaa
    16081 aaatcgcatt actggaaccg gagatacagc tggacttatt gatgagtact tctgataaaa
    16141 agatccaact agcagcagaa accccttata tagaaggagt acatccaaaa aatacttggt
    16201 tgttcgaaca tccagtccag gcagctgatt ttccaaaagc aattcgtgca tggacgatta
    16261 acgatgaaga agaaatggcc aaatgtcaag aactcaaaat agatggaata ataactgatt
    16321 ttccggagaa agctcttcgg tggaaacaat caacgaaaag taggtaaaat atggaaaaag
    16381 tattagtgat cgtcggtccg acagcagtcg gtaaaacagc gctaagtgtg gaactcgcac
    16441 aactatttgg aggagagatc atcagtggtg attcattgca aatctataaa aatctggata
    16501 tcggtacagc aaaaatcaaa gaagaagaga tgaataatgt tccgcatcat ttgattgatg
    16561 tgatcgaacc tactcaacgt tactcagccg ctgattttca gcattcaggt cgacaattga
    16621 ttaccgagat tgcgaaccga gggcacctac ctatcatagc tggtggtacg ggtctctata
    16681 tccaatccct tctatatgat tatcagttag gagcgacaga agaagcgaat cctgagatta
    16741 gaaaaaagta tgaaacgtta gctgaaacaa ttggttccca agcattatgg aatcagttga
    16801 aagaaaaaga cccggcagct gctgagaaaa tccactggaa caatcaacgc aaagtgataa
    16861 gagctctgga agttttagag acgacaggac atagtatcac ggcacctaaa gaagagccaa
    16921 agcaattgta tgattacctc atgattggat tagatacgaa gcgtagtatt ctttatgaac
    16981 gaatcaatca aagagtcgat ttgatgctag cagaaggttt agtagcagaa gcgcgtaagg
    17041 tgtatgagct tggagaagtc caggccagtc aaggtattgg atataaagaa tttttccctt
    17101 attttgaagg gaaagaaaca ttggaagaag caacagaaca agtcaaacta cattcgagaa
    17161 gatacgcgaa acgtcagttg acgtggtttc gtaaccgttt ggatgcacag tggtttgatc
    17221 ttataagtga gccaaatcaa aaaagtcaga ttgagcaaac aatcaaaaaa tggctggagg
    17281 cggaataaaa tggaagaaaa agtgatcatc gtaggggtag aaaccgaagc aaaccagcgt
    17341 tacttttcag agtcaatgga agagctagtt cagctgacga ataccgcatc aggagaagtc
    17401 gtattcacaa ttacacaaaa gagaccacaa gtggatcggc aaacgattat cggtaaaggg
    17461 aaattacaag aattagttca acaagcggat gcgcatgaag cggatttgat catctttaat
    17521 catgagctaa ctccgagaca gagccaactg attaccgatg ctgttggtct tccggtaatt
    17581 gatcgcgtgc agcttatctt agatattttt gcgatgcgtg ctcgttcgaa agaagggaag
    17641 ctgcaggttg aacttgctca gttagaatac ctgctgcctc gtttagtagg gcaagggaaa
    17701 acattatctc gtcttggcgg tgggatcgga acaagagggc caggtgaaac aaagttagaa
    17761 acagaccgcc gacatatacg gaataaaatt tttgctgtta agaaagaatt gaaagaagta
    17821 gaagctcatc gagagcgcaa tcgccaaaaa agaaaaaata gcgagatttt tcagattgga
    17881 cttattggct acacgaatgc cgggaagtca actatcttga atctattgac acaagcggat
    17941 acttattcga aagatcaatt gtttgcaacg ttagatccat tgactaagag atggcgtttt
    18001 gctgaaggat ttgagattgc tgtaacggat accgtcgggt tcatccaaga cctgcctacg
    18061 caactgatcg atgctttcca ttctacatta gaagaaagtc aaaatatgga tcttttgcta
    18121 catgtagtcg atgctagttc tccagatcgt attttacagg agcagactgt cttaaaattg
    18181 atggatgaac tgaatatgaa agaaatgccg atactgactg tttacaataa ggcagaccag
    18241 atcgacccag cgatgttcac gcctacgcta ttcccaaatg tattgatttc tactcagacg
    18301 aaagaaggta agatggcgtt gatcgaagca atcaaacgtc agctgatgga actaatgacc
    18361 ccttatacac tttctgtgcc aagcaacgaa ggacagaaat taagcgagtt gagaagacaa
    18421 acaatggttt tggacgaagc gtacatggaa gaaacaaacg aatatgaagt taaagggttt
    18481 gcaaaaacca attcaaaatg gttaagaaaa aaccaataaa attttatttt tttaa
//
LOCUS       DAZKCW010000048        18107 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000048 DAZKCW010000000
VERSION     DAZKCW010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.048"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(164..388)
                     /locus_tag="ACG84Z_001980"
     CDS             complement(164..388)
                     /locus_tag="ACG84Z_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFP9162793.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(586..2166)
                     /locus_tag="ACG84Z_001981"
     CDS             complement(586..2166)
                     /locus_tag="ACG84Z_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFP9162794.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2567..3943)
                     /locus_tag="ACG84Z_001982"
     CDS             complement(2567..3943)
                     /locus_tag="ACG84Z_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFP9162795.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4071..5159)
                     /locus_tag="ACG84Z_001983"
     CDS             complement(4071..5159)
                     /locus_tag="ACG84Z_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFP9162796.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5331..5765
                     /locus_tag="ACG84Z_001984"
     CDS             5331..5765
                     /locus_tag="ACG84Z_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9162797.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5843..6376)
                     /locus_tag="ACG84Z_001985"
     CDS             complement(5843..6376)
                     /locus_tag="ACG84Z_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFP9162798.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="ACG84Z_001986"
     CDS             complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="ACG84Z_001986"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFP9162799.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7641..8438)
                     /gene="recX"
                     /locus_tag="ACG84Z_001987"
     CDS             complement(7641..8438)
                     /gene="recX"
                     /locus_tag="ACG84Z_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFP9162800.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8545..9927
                     /gene="rlmD"
                     /locus_tag="ACG84Z_001988"
     CDS             8545..9927
                     /gene="rlmD"
                     /locus_tag="ACG84Z_001988"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFP9162801.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10101..10679)
                     /locus_tag="ACG84Z_001989"
     CDS             complement(10101..10679)
                     /locus_tag="ACG84Z_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFP9162802.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11001..11471
                     /locus_tag="ACG84Z_001990"
     CDS             11001..11471
                     /locus_tag="ACG84Z_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFP9162803.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11579..12805)
                     /locus_tag="ACG84Z_001991"
     CDS             complement(11579..12805)
                     /locus_tag="ACG84Z_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFP9162804.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(13559..13759)
                     /locus_tag="ACG84Z_001992"
     CDS             complement(13559..13759)
                     /locus_tag="ACG84Z_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9162805.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(13893..14501)
                     /locus_tag="ACG84Z_001993"
     CDS             complement(13893..14501)
                     /locus_tag="ACG84Z_001993"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFP9162806.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(14586..15056)
                     /locus_tag="ACG84Z_001994"
     CDS             complement(14586..15056)
                     /locus_tag="ACG84Z_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFP9162807.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(15104..16018)
                     /locus_tag="ACG84Z_001995"
     CDS             complement(15104..16018)
                     /locus_tag="ACG84Z_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFP9162808.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            16164..16967
                     /locus_tag="ACG84Z_001996"
     CDS             16164..16967
                     /locus_tag="ACG84Z_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFP9162809.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            17145..18092
                     /locus_tag="ACG84Z_001997"
     CDS             17145..18092
                     /locus_tag="ACG84Z_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFP9162810.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         5438 a         3631 c         2964 g         6074 t
ORIGIN      
        1 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
       61 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
      121 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
      181 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
      241 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
      301 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
      361 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
      421 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
      481 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
      541 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
      601 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
      661 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
      721 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
      781 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
      841 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
      901 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
      961 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
     1021 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
     1081 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
     1141 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
     1201 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
     1261 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
     1321 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
     1381 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
     1441 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
     1501 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
     1561 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
     1621 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
     1681 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
     1741 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
     1801 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
     1861 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
     1921 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
     1981 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
     2041 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
     2101 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
     2161 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
     2221 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
     2281 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
     2341 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
     2401 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
     2461 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
     2521 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
     2581 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
     2641 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
     2701 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
     2761 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
     2821 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
     2881 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
     2941 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
     3001 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
     3061 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
     3121 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
     3181 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
     3241 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
     3301 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
     3361 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
     3421 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
     3481 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
     3541 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
     3601 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
     3661 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
     3721 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
     3781 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
     3841 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
     3901 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
     3961 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
     4021 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
     4081 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
     4141 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
     4201 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
     4261 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
     4321 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
     4381 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
     4441 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
     4501 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
     4561 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
     4621 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
     4681 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
     4741 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
     4801 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
     4861 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
     4921 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
     4981 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
     5041 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
     5101 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
     5161 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
     5221 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
     5281 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
     5341 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
     5401 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
     5461 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
     5521 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
     5581 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
     5641 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
     5701 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
     5761 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
     5821 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
     5881 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
     5941 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
     6001 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
     6061 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
     6121 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
     6181 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
     6241 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
     6301 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
     6361 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
     6421 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
     6481 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
     6541 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
     6601 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
     6661 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
     6721 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
     6781 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
     6841 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
     6901 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
     6961 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
     7021 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
     7081 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
     7141 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
     7201 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
     7261 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
     7321 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
     7381 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
     7441 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
     7501 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
     7561 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
     7621 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
     7681 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
     7741 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
     7801 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
     7861 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
     7921 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
     7981 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
     8041 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
     8101 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
     8161 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
     8221 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
     8281 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
     8341 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
     8401 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
     8461 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
     8521 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
     8581 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
     8641 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
     8701 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
     8761 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
     8821 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
     8881 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
     8941 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
     9001 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
     9061 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
     9121 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
     9181 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
     9241 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
     9301 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
     9361 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
     9421 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
     9481 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
     9541 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
     9601 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
     9661 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
     9721 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
     9781 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
     9841 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
     9901 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
     9961 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    10021 gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga catagttttt
    10081 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    10141 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    10201 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    10261 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    10321 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    10381 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    10441 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    10501 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    10561 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    10621 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    10681 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    10741 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    10801 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    10861 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    10921 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    10981 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    11041 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    11101 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    11161 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    11221 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    11281 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    11341 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    11401 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    11461 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    11521 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    11581 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    11641 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    11701 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    11761 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    11821 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    11881 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    11941 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    12001 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    12061 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    12121 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    12181 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    12241 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    12301 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    12361 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    12421 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    12481 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    12541 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    12601 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    12661 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    12721 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    12781 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    12841 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    12901 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    12961 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    13021 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    13081 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    13141 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    13201 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    13261 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    13321 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    13381 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    13441 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaaat ctaaaaactt
    13501 cataaataga caaaaagaca cgactctcta agaagtcgtg tctttattca acaaattatt
    13561 ataatttagt cacttcagca gcttgaggtc cgcgtgcacc ttcaacaatc gtgaattcta
    13621 cttcttgacc ttcttctagg ctcttgaagc cgtctccttg aattgctgag aaatgaacaa
    13681 atacgtcatc tccgccgtct actgtaataa acccaaatcc tttttcattg ttgaaccatt
    13741 taaccgttcc gtgttccata aatgtatatc ctccaaaaaa gttcttgcaa gtaaccttgc
    13801 aagaacatta tacccaattt agaaaacgct agcaagcttt cgctctttta ttttccaaat
    13861 tatttttaag actgatatga cggaggaaat ggttattttg ctgcttcgaa acgtttgttt
    13921 acttcatccc aattaataac attccagaat gctgcaatat aatctggtcg gacattttta
    13981 tatttcaaat aataagcatg ttcccaaacg tccaaaccta gaattggtgt ctttccttcc
    14041 atcaatggag aatcttgatt tgcagtagag gtaatagcta attttccatt ttccattaca
    14101 agccaagccc atccagaacc aaatcgtcca gcggctgctt ttttgaattc ttctttaaaa
    14161 gaagaaaaat caccaaaagc ttcattaatc gcttctttta tttctcctgt aggttcgcca
    14221 ccagcatttg gtgccatgat ttcccagaaa aatgaatggt tagcatgtcc gccaccattg
    14281 ttacgtacag ctgtcttgat atctgttgga atagcgtcca tatcagataa taattcttct
    14341 attgtttttt cgcctaattc tgggtatttc tcaattgctg aatttaaatt cgtcacataa
    14401 gtattgtgat gcttatcatg atgcagatgc atcgtttctt cgtcaatata aggttccaat
    14461 gcgtcatatg cataaggtag atctggtaat gtgtaagtca taaaaaaatt cctcctcaat
    14521 gttttcttaa taatgtctac attacaaaga gtaacaaaga gaaggaaatt cttcaattgt
    14581 tatgcctagt cgtctttttc actttgacct acttcttctt caaaaacctc agtttcttta
    14641 aaaataaaca acttgctgaa aatatagttc gcaaggataa caataatttg agtgatgatt
    14701 ttcgccacat actcattgct gttcataaca ttgatcaaca ataccattgc ccccatgtcc
    14761 aatccgtaag aaaggatacg gtagaagaag aacttaccgc attcaataag tgcatgtgta
    14821 aaattcggtg attttgaatg gaatacccaa agtttgttcg ttacaaaagc aaacaataca
    14881 gaacaaaacc acgaaataga attggataag gccatactta aatcaaaata ttggcgtgcg
    14941 agagcaaaac taacaaaatt tacaatcgta gccaaaccac caaaaaagag atagactagt
    15001 atctcccaat atccttttgc ttctaaatat ccttttaact gtcgatactg cttcatgagc
    15061 caacctacct tattaaaaat tcttatttat catactctat atttcaataa ctttcatctt
    15121 tatttaaaaa aattaatttt ttttgatcct ttgcctttgt ctctgcttgg atcgtcacat
    15181 gtgtaatacc atattttaat tttaataaag aaattatacg aggatatatc ttttcaatct
    15241 cgcttagtag ctgatcttca aaatcaatat gtccgtcgaa aataattatc ttttcgctat
    15301 actgccaaat atggacatga tgaacatcct ttaccccatc gattgcttca atttcttgtt
    15361 ccattttttc atagtcgata gcaggtgcac tttgtatcaa aatagcggca gcttttttga
    15421 tcaccattat cgcttctatc aatatatata tcgaaatgat cagtgtaata actggatcga
    15481 tccagtagat atcgaaaaaa cggatcaaaa ttgctccgat aatcacactt accgaagaca
    15541 gtgtatcact taacaaatgc aaataactag attttatatt caaactttca tctgcttctt
    15601 gtcgtaataa taatactgag aacaaattcg cgagcaatcc aataactgct actgttagca
    15661 tcaaatgact atttatcttt tctggtgaag tgaaccgctt gaatgcttca acggttaaaa
    15721 acaaggataa tatgatcaat atgaatgagt tgatgaaagc actcaatatt tctaaacgct
    15781 ggtagccata cgtacgtttt ttatttgctt cttttcgggc cattttttgt gccccgtaag
    15841 aaaaaataat tgccaatgta tcactaaggt tatggaaagc atctgaaaca agagacaaac
    15901 tccctgacat aatccctcca ataaattctg ataaagtgat caccgcattc aaaaccacta
    15961 ctccaaatag tttttttgat gatctctgtg gctgtgtagg cactattcct tcctccattt
    16021 tatttatatt ggatagtctt tagacaagaa taacattttt ttgatatttc accaatcatt
    16081 cagctgtttc cttaaagcac ttgtatttca cttgatactt cgctagaatt gcaagtgatg
    16141 acactactag atgaggagta cttatgacaa caaaacaatt aattatcagt tcctttatac
    16201 gattcaaaga cctaaaggag gcgagaaatg tcccattttg gaaagccatt gtctatcttt
    16261 tagttttgag tataattatg gctttgccaa tctcttttca agtttttcaa gtcttaaaca
    16321 acattcaatt ggatgggcaa aagattgcta ctcgcattcc tgattttaca atccaaaacg
    16381 ggcagcttca aaccgaagaa aaagaaggat tcatttacca aacaaactcc attatcttca
    16441 catttgatcc agagggaaaa cgaacagaac aggacatctc tactgatttg atggggaatt
    16501 ttgttagtgt cgggatgtta aaaaacaaac ttatcatagc tcttcctaat acaggcacga
    16561 cttctgcttt gttgaacaat aaccaattag aacttcccta caccaatgaa tctttaaaaa
    16621 acttaacagg taagcagctc cgttcttttt taagtgaagc atctatacca ctttggataa
    16681 aagtcctgac atttatattt tctatttatc ctagttttct gaatctgctg atcactttgc
    16741 tatttaccaa cattgctgct tttctctatg cacgctttcg actaacaaaa gctacttttc
    16801 ttgattgttt aaaaacattg atctattcaa tttcattgcc tactataatt gcaacaatct
    16861 tgatggtctt tcttccttct tttgacacta gcgccttcat tgcttttgca ggaatcttta
    16921 tttttgctca agctgtcaaa ggatgggcaa aaatatcgat caattaagaa ataaagacaa
    16981 ctcgttattt ctacttcaat agaccctttt agaggttgtg acattttttt gtcacagccc
    17041 cttttttatt tgaaaaatat ttctttctca aaaaacaagc aaggcgcttc aaagttcttc
    17101 ttgtatgcgc tacacttaga gtaaagaaag gcgggaaatt aactatgtca gaaagaatca
    17161 tttatgcaga tcgtccattt cgtgatgaat ttatcgaaga aatccatact atagcgcctg
    17221 gttatatctt taaaacagaa ttacaaccag aggatctaca aaatgtagag atcagtttgg
    17281 gctggaactc agactaccaa gaaaaactat tagcctcttc taccttgaaa tgggtccaat
    17341 ctatctcagc tggtgttgat cagctacccc ttgagacttt ttcaaagaaa catattttac
    17401 tttcaaatgg tagtggcatc cacagtgaat cgattacgga gcatgtctta ggaatcatcc
    17461 ttgggtattc tcgtggtctt tttcaagcac aaaaggcaca gagtgacatg aaatggttag
    17521 gttcatcggt ccattaccaa tctatccaag ggaaaaaaat actaatcatt ggaactggcc
    17581 atattggaaa aatgattgca aaaaaatgca aagcattaga catgaactgc tatggaatca
    17641 atacatccgg tcatccagca gaaggaatgg aaaagacttt ttctttaaat caactaaagg
    17701 aagttcttcc tgaagtagat ttcgtagtca atatcttacc tctaacggag gaaacaactg
    17761 ggctctttga tcagcatatg tttgaacact ttgatccaaa atctgtattc atcaatgttg
    17821 gccgtggtgc ttctgttaag acacaagatc tggtgcaggc tttaaataac cagcaacttt
    17881 cctttgcagc attagacgtt tttgaggaag agcctcttcc acaagatcat cctctttgga
    17941 aaatggacaa tgtactgatt acttcccaca ttgcaggttt gacacctgat tttcaaaaga
    18001 aattaatggc tattttttta accaatctga aaagctactt tgccacccat gagcttcaaa
    18061 ccaatcaagt aaaattgtct gcaggatatt aatagctgaa aacaata
//
LOCUS       DAZKCW010000049        18016 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000049 DAZKCW010000000
VERSION     DAZKCW010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.049"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(24..722)
                     /locus_tag="ACG84Z_001998"
     CDS             complement(24..722)
                     /locus_tag="ACG84Z_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFP9162811.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="ACG84Z_001999"
     CDS             complement(715..2067)
                     /locus_tag="ACG84Z_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFP9162812.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="ACG84Z_002000"
     CDS             complement(2290..3690)
                     /locus_tag="ACG84Z_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFP9162813.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="ACG84Z_002001"
     CDS             3851..4588
                     /locus_tag="ACG84Z_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFP9162814.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="ACG84Z_002002"
     CDS             4713..5192
                     /locus_tag="ACG84Z_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFP9162815.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="ACG84Z_002003"
     CDS             5189..5956
                     /locus_tag="ACG84Z_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFP9162816.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="ACG84Z_002004"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="ACG84Z_002004"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFP9162817.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6859..7461)
                     /locus_tag="ACG84Z_002005"
     CDS             complement(6859..7461)
                     /locus_tag="ACG84Z_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFP9162818.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7567..7797
                     /locus_tag="ACG84Z_002006"
     CDS             7567..7797
                     /locus_tag="ACG84Z_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162819.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            7788..8036
                     /locus_tag="ACG84Z_002007"
     CDS             7788..8036
                     /locus_tag="ACG84Z_002007"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9162820.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            8142..8726
                     /locus_tag="ACG84Z_002008"
     CDS             8142..8726
                     /locus_tag="ACG84Z_002008"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFP9162821.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8729..9802
                     /gene="prfA"
                     /locus_tag="ACG84Z_002009"
     CDS             8729..9802
                     /gene="prfA"
                     /locus_tag="ACG84Z_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFP9162822.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9795..10634
                     /gene="prmC"
                     /locus_tag="ACG84Z_002010"
     CDS             9795..10634
                     /gene="prmC"
                     /locus_tag="ACG84Z_002010"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFP9162823.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10627..10806
                     /locus_tag="ACG84Z_002011"
     CDS             10627..10806
                     /locus_tag="ACG84Z_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162824.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10828..11853
                     /locus_tag="ACG84Z_002012"
     CDS             10828..11853
                     /locus_tag="ACG84Z_002012"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFP9162825.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12028..13272
                     /gene="glyA"
                     /locus_tag="ACG84Z_002013"
     CDS             12028..13272
                     /gene="glyA"
                     /locus_tag="ACG84Z_002013"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFP9162826.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13425..14372
                     /locus_tag="ACG84Z_002014"
     CDS             13425..14372
                     /locus_tag="ACG84Z_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFP9162827.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14506..15135
                     /gene="upp"
                     /locus_tag="ACG84Z_002015"
     CDS             14506..15135
                     /gene="upp"
                     /locus_tag="ACG84Z_002015"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFP9162828.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15274..15516)
                     /locus_tag="ACG84Z_002016"
     CDS             complement(15274..15516)
                     /locus_tag="ACG84Z_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162829.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15637..15709
                     /locus_tag="ACG84Z_002017"
     tRNA            15637..15709
                     /locus_tag="ACG84Z_002017"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15670..15672,aa:Thr,seq:cgt)
     gene            complement(15828..16466)
                     /locus_tag="ACG84Z_002018"
     CDS             complement(15828..16466)
                     /locus_tag="ACG84Z_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFP9162830.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16589..17221)
                     /locus_tag="ACG84Z_002019"
     CDS             complement(16589..17221)
                     /locus_tag="ACG84Z_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFP9162831.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17572..17871
                     /locus_tag="ACG84Z_002020"
     CDS             17572..17871
                     /locus_tag="ACG84Z_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFP9162832.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT         6169 a         3154 c         3557 g         5136 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
     6841 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
     6901 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
     6961 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
     7021 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
     7081 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
     7141 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
     7201 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
     7261 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
     7321 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
     7381 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
     7441 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
     7501 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
     7561 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
     7621 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
     7681 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
     7741 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
     7801 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
     7861 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
     7921 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
     7981 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
     8041 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
     8101 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
     8161 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
     8221 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
     8281 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
     8341 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
     8401 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
     8461 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
     8521 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
     8581 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
     8641 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
     8701 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
     8761 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
     8821 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
     8881 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
     8941 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
     9001 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
     9061 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
     9121 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
     9181 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
     9241 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
     9301 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
     9361 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
     9421 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
     9481 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
     9541 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
     9601 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
     9661 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
     9721 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
     9781 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
     9841 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
     9901 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
     9961 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    10021 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    10081 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    10141 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    10201 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    10261 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    10321 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    10381 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    10441 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    10501 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    10561 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    10621 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    10681 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    10741 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    10801 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    10861 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    10921 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    10981 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    11041 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    11101 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    11161 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    11221 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    11281 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    11341 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    11401 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    11461 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    11521 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    11581 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    11641 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    11701 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    11761 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    11821 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    11881 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    11941 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    12001 taggaaaata aaaaggagct gttgtttgtg gtagattaca aaacgtttga ccctgatctt
    12061 tgggctgcga tcgccaaaga agaagaaaga caagaacata atttggagct gattgcctct
    12121 gaaaactttg tctccgaagc agtgatggct gcacaaggaa gtatcttgac aaataaatac
    12181 gcagaaggtt atccagggca tcgctattat ggtgggtgtg aatttgtcga tatcgttgaa
    12241 aatttagcga ttgaccgtgc aaaagaatta ttcggagcga aatttgcgaa cgtccagcct
    12301 cactccggct ctcaagccaa cacggctgct tatctcgctt tggtagaacc aggggacacg
    12361 atcttaggaa tggatctttc cgcaggcgga catctaacac atggatcacc agtcaacttc
    12421 agtggcaaaa cctatcactt tgttgcttac ggtgttgatc cgacaacaga agttattgat
    12481 tataatgtgg tacgtatttt agctagaaaa catcaaccaa aattgatcgt agcaggtgcc
    12541 agtgcttacg gacgaacgat cgactttgcg aaattcagag aaatcgcaga tgaagtaggc
    12601 gcaaaactga tggtagatat ggcacatatc gcaggattag tagcagcagg acttcatcct
    12661 aatccagttc cttatgcaga tatcacaacg actaccactc ataaaacatt gcgtggccct
    12721 cgaggcggca tgattttgac aaacgatgaa gcattagcaa aaaaaataaa tagtgcggta
    12781 tttcctggta ttcaaggcgg ccctctagag catgtgattg cgggtaaagc agtagcattc
    12841 aaagaagcat tagatcctgc atttaaagaa tatagtgaac aaatcatcgc caatgcaaaa
    12901 gcaatggtca aagttttcaa tcaagcaatt ggaaccagag tcatttcagg ggcgacagat
    12961 aatcatctga tgttgatcga tgttcgcgag ttaggtataa atggaaaaga agcagagagc
    13021 attttggaca gtgtgaatat cactgtaaat aaaaactcga ttccttttga aacactaagt
    13081 ccattcaaaa caagcggtat tcgaatcggc acgccagcaa tcactactcg cgggttcaaa
    13141 gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag cattacaagc aaaagatgat
    13201 aacgctcaac tagacgaagt caaaacaggt gtacgcgaat taactgaaaa atttccgttg
    13261 cataaaaaat aaaaatttaa attccattag taaacagaaa agttcaatgt tgggcttttc
    13321 tgtttatttt ttgggaaaac ggattctttg acaatatcgg tgatgctctc tagtatatga
    13381 ggtgtaattt tagtcttcac actaaatctc agggaggaaa agtcatgact gatcgtatct
    13441 cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc gcctcatccg cgtatctatg
    13501 aactagcacc ggaagaagga agagttttac tagaagaagt acaagaatca cctgtgaaca
    13561 aatattccgt cgatattgaa gacttgatgg tggatactgg cgaatgggga aaactcaata
    13621 ttcgtctcgt acgaccagaa gggaatatgg ataaattacc agttattttt tatattcatg
    13681 gagcaggctg ggtttttggc agtgctcaaa cccatgataa attgatcaga gaacttgcgg
    13741 ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg atcaccagaa gcaaaatatc
    13801 caacagcaat tgaacaaaat tatgctgtgt tgcaacagct gaataaatta gccaagtcaa
    13861 aaaatctgga tctcgagaat ctaatcgttg caggagattc agtaggtggt aacatggcta
    13921 cagtcatgac gatcttaaca aaagaacgaa agggcctccc aatatccaag caattgctgt
    13981 attatccagt cacaaacgct gattttgata cagattccta tcatgaattc ggagaaaact
    14041 attttttgac aagagaagga atgatgtggt tttgggacca atatacgacg aatgaagaag
    14101 agcgtgctga aatcacagct tcgcctttga gagcaaatat aaatgaacta aatgatcttc
    14161 cttcagcaat gattttaacg ggagaagcgg atgtattaag agatgaaggt gaggcttatg
    14221 cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt acgcttccaa ggaatcatcc
    14281 atgattttgt catggtaaat gctatggatc agacaaaggc aacgcgtgca gcaatggcat
    14341 tatctacttc ttggatcaag aaaaaagaat aagctttgct tgtccgcagg aaaacttctt
    14401 ttcaaaaacg gattttctta ggaaaaatgg cgagtttgac tagtcaatca cttgattttg
    14461 ttttacaatt aaaaagaaac gacagaacaa aggagagctt aaaaaatggg caaatttcaa
    14521 gtgatcgatc atccattgat tcaacacaaa ctaactatta ttcgggacaa aaactgcgga
    14581 acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt tgatggcata tgaagtatca
    14641 cgggatatgc cattggaaga catcgtgatc gaaacaccga tcactgaaac aacacaaaaa
    14701 acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc gcgcaggtat tggaatggtt
    14761 gacggtatct tggaattgat tccagctgct aaagtgggac atatcggtct ttatcgagat
    14821 gaagaaacat tggaaccaca tgaatatttc gtcaaacttc cagaagacat tgatgcacgt
    14881 cagttgtttg tagtagatcc aatgttggca acaggcggat cagcaatcat ggcaatcgat
    14941 gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt gtttggtagc agcacctgag
    15001 ggagtaaaag ctttgcaaga agcgcatcct gatattgaca tctatacagc ttctctagat
    15061 gaaaaattga atgaacatgg ttatatcgtt cctggactag gggatgcggg tgaccgtttg
    15121 tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac aacttttgtc acatcctttt
    15181 ttggtcattt ttaacgtttg atgcagaaca gctttttcac agctttcgtt tgcatataaa
    15241 aaaaccatcc caaaaatgca gagatggtca aattcaaatc ttttttagtt ctttgtagtt
    15301 aacgattact acacccttac tttgcgtcat caagttcgca ttttctgcag tttcatcaat
    15361 ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt ccagtttgcg acttgccgtg
    15421 aattgtgaac attacgtgag tattgatctt gaatttttca ccaatttccg atggtacgat
    15481 agttgtatca aattttccaa aagttgccat tttcataaaa cctgcctttc acatcaatta
    15541 taccacgttt tatgaaaaat atcatgaaat taaactaatt ttccatcgga ctctttacaa
    15601 tcagccaaat agagtatata atttcttttg gataaggcca gcttagctca gttggtagag
    15661 caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta tagctggcat taaaagagaa
    15721 gacagatata tcaaggattt ttaatccatt gatacatctg tctttttgtt taaaggaaat
    15781 aaagtatgct ttcttagcaa tagagcatgt attatttcta taaaaattta ggagaataaa
    15841 acgactagca atatagctgt gaaatcaaat atcacatgaa ctgcccaact tgtaatgatc
    15901 gagttgcttt taatggcagc ttggttgaat aacaatcttg ccaccccttg tatcaaaagg
    15961 atgtgtgcta cagtgtgtaa aatatttcca ttatcataag tactgtaatg gataaatcca
    16021 aagatgattg ctgacaagaa actagcgaca ggaatgctga acttactaga aaaaatagcg
    16081 agaaaataca ctgagaacaa ttcttctcca agtatcatga taggcaaaat aataaataat
    16141 aacgggctga aagcctcatt tattggattg cctgttaaac cccatttcaa aatttgttgc
    16201 aaaaataccg agactgcggc actgattact acattgataa aaaaatattt ggctatattt
    16261 ttgacaggag cgacaggttt cgagaacatt tttttcgtat cttttttacc aaaaacaagt
    16321 gtaaatgcta taaatccagt gatagttaaa gaaaaaatgc taataatgga tggcgcaaat
    16381 agcaacccta acaaaccgag tacaacgaca atagtgccca atatcccttt tttaagttct
    16441 attttttttc ctaaaatgtt attcatgata ataactccta ctattcagtt tttgaagata
    16501 gagtcagtat acatgaagag ttaaaatagg caatgttttt ttatggatat ttgtattgct
    16561 aaaaatttat cttatatatt cattttgatt atactacttt tatttgtaaa aattttctag
    16621 caaaaccaag tgcttgcaac tgattaagcg tacaattttt tagatgttcc gagcgtactt
    16681 caatcatttc aaaggagttg ctacttaaat cgatattttt taaatcagta tcaaaaaagc
    16741 tagcattttc taaatcatta gtagaaaaca ttattttagt gagggaacag tctacaaaat
    16801 ctgcgcttga taagacagag tgctcaaagg tactttcttt tatgtttgaa ccagataaat
    16861 ttacatagtc cattttacaa ttctcgaata acgtgttccc aatataactt tccatcaatt
    16921 tagtacctgt taatttacaa ttgacaaatt tcacgcgatg caacatgctt tttgtcaata
    16981 tacagcctga aaaatcacag ttttcgaata tacagtcggt aatctccatt ctttgaaaat
    17041 cattggaagc aaaaaatgca tacttgaaaa tagatttgta aataattgga tggcagatta
    17101 tttggttttc gatgacctct ttttgtgaaa ggatattata cagttcaaaa tcttcgtttt
    17161 catagatatg aaaaaaggat cctttattca agcttgcttc attaacttta ggaaaaatca
    17221 tatttaatta cctccatttt cataaagtca tattaacaaa agctaaacca acttacatta
    17281 gcagaaaatg agataggttt tcgccttttt cgataacgat agtgtcgcta tctcttgaaa
    17341 cgttcttaga attgccctga gagacacaaa ttaggcgtaa ttctaataaa aatcttagaa
    17401 taaaaatttt tactgattta atttagaatg tttttaaaat aaaaatcgtt gccataacag
    17461 tgtattgaaa ggttttaaca atccagtaat gatttaaaaa aatctagatg tagcgtatac
    17521 tttgtttata gaatgtagtg ggaagaaata tatttttggg aggaaatcgt gatgtctaaa
    17581 agtgaagaaa tagaaaacat ggtactaaaa ttatatgatc tcgttttaaa tccagagatc
    17641 aaagaaaagg aacgtatact tttgatagac gcaaagacag gcttagaaaa aggtcagtat
    17701 tatcctaaag tcataaataa tttggaacgt agtttacgtc cgttagcaat caggggagaa
    17761 ttgtctaaac cagtatcacc gttttatatg gagatatcaa caataggaaa atttgaaaaa
    17821 gaattaggtc gaggaatggc ttcggcaccg attacttttg ggcatttata aaaacgagtt
    17881 attcatctca atgaattaaa aagtatagtc aatctcataa tgcaggctag gttcatttat
    17941 ttgaacagag tctgtatttt tttattctaa ataaagaaac agatgtttct ttatattgta
    18001 ttttatcctt taatta
//
LOCUS       DAZKCW010000050        17165 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000050 DAZKCW010000000
VERSION     DAZKCW010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.050"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(37..846)
                     /locus_tag="ACG84Z_002021"
     CDS             complement(37..846)
                     /locus_tag="ACG84Z_002021"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9162833.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            1139..2575
                     /locus_tag="ACG84Z_002022"
     CDS             1139..2575
                     /locus_tag="ACG84Z_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFP9162834.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            2745..3941
                     /locus_tag="ACG84Z_002023"
     CDS             2745..3941
                     /locus_tag="ACG84Z_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFP9162835.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(4003..4188)
                     /locus_tag="ACG84Z_002024"
     CDS             complement(4003..4188)
                     /locus_tag="ACG84Z_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFP9162836.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            4419..7733
                     /gene="dnaE"
                     /locus_tag="ACG84Z_002025"
     CDS             4419..7733
                     /gene="dnaE"
                     /locus_tag="ACG84Z_002025"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFP9162837.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            7901..8863
                     /gene="pfkA"
                     /locus_tag="ACG84Z_002026"
     CDS             7901..8863
                     /gene="pfkA"
                     /locus_tag="ACG84Z_002026"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFP9162838.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            8937..10721
                     /gene="pyk"
                     /locus_tag="ACG84Z_002027"
     CDS             8937..10721
                     /gene="pyk"
                     /locus_tag="ACG84Z_002027"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFP9162839.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(10756..11658)
                     /locus_tag="ACG84Z_002028"
     CDS             complement(10756..11658)
                     /locus_tag="ACG84Z_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFP9162840.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            11844..12413
                     /locus_tag="ACG84Z_002029"
     CDS             11844..12413
                     /locus_tag="ACG84Z_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFP9162841.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            12471..12650
                     /gene="rpmF"
                     /locus_tag="ACG84Z_002030"
     CDS             12471..12650
                     /gene="rpmF"
                     /locus_tag="ACG84Z_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFP9162842.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            12820..14241
                     /gene="gndA"
                     /locus_tag="ACG84Z_002031"
     CDS             12820..14241
                     /gene="gndA"
                     /locus_tag="ACG84Z_002031"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFP9162843.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDEAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            14434..15120
                     /locus_tag="ACG84Z_002032"
     CDS             14434..15120
                     /locus_tag="ACG84Z_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9162844.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            15117..16622
                     /locus_tag="ACG84Z_002033"
     CDS             15117..16622
                     /locus_tag="ACG84Z_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9162845.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
BASE COUNT         5553 a         2979 c         3593 g         5040 t
ORIGIN      
        1 tgtcacaacc tcttttttgt ggaatctaat tctctattat agtttaagta gtttttccag
       61 ataaacagct aaaccgtctt cctgattgct caaaggagtg acatcatttg caatgccttt
      121 gagttggtca gtaccgttag ccatagctac tccccaacct gcataatcca acaattccaa
      181 atcattatgc tcgtcaccaa aggcaatgac gtctttttga tcgatagaca ggtagttagc
      241 aatctcttgc acgccttttg ctttttggat tccttttgaa acaatctcta agatggcagt
      301 aggtccaccc catgtccgaa catcgacata actgccaaat tgacgtgtta attcagcaga
      361 tacagctcct gcaaaacgtt tgtctgttcg gacaagcaaa gatgtaggat ttgtcgtcaa
      421 atttttagga gaaagcaaat tcttctctcc tggacgagaa gaagcaaaaa ttttttcatc
      481 aaagaaatca aaactgtcaa taaaaaaagt atcacgattt tcagcagcga taaaatctaa
      541 atttagctgc tttttttgcg ataagatttc aaaagcgatt tcacgattga tcaacgtttc
      601 tctttcacca tcccagtgct gattagggat gtgtactaat gcgccgttaa aattaaccat
      661 cggtgttgtt aattctaatt gttggtaaaa ctgatggctc attcggaatg ggcgtcctgt
      721 agcaatactg acatgatgac cggcattgat tgcttttttt agagtctctt ttgttttaga
      781 tgtaatcatc gaatcttgat tgagggtagt tccgtccaga tcgatggcaa ttaatttttt
      841 attcaataag ggtccttcct tcctcaacta gcatttgttt tagtctagca tattttaggt
      901 aattaacaag agcaatcagc tattcctaac aaaaactaca gttatggcta tataaatagc
      961 taaacataag ctaaacacga acgttaagta ttattttcgc tttttttgtt aaaaaaacgt
     1021 tgaaaagcga atgaaacgtc tatataattt gaaattgttc gatggatttg ccctatttta
     1081 cttatttttt attattatag ttttccatca gaaaaaaatt cagggagtgg aactttttat
     1141 ggaaaagttt ttcggtttaa agaaaaacaa tacaaatgta tcaactgaaa taatggcggg
     1201 agtaacgaca ttctttgcca tgagttatat cttattcgta aatccgacga ttttgtcagc
     1261 atcaggtatg cccttccaag cagtatttct agcgacaatc attgcatcga ttattggtac
     1321 gctggtaatg ggattgttcg caaatgtacc atatgctcag gcacctggta tgggattgaa
     1381 cgcatttttc acttttacgg tcgtttttgg gcttggttat tcttggcaac aagccttggc
     1441 aatggtgttt atttgcggat taatcaatat ttttattact gtcacaaata ttcgaaaaat
     1501 gattattcgg gcgattcccg aaagtcttca acatgcgatt ggtggcggga tcggtatttt
     1561 cgttgcgtat gtcggaatca aaaatgcagg attcttatct ttttcagcag accagtcagc
     1621 tatttcgagc tctgtcgttg aaggcggaaa agcgacaaat gttacgataa atggtggaat
     1681 cgtccctgcg ttagccaact ttgacaacgc tcctatctta ttggctgtga ttggtttggt
     1741 actgacagcc attttagttg taaaaaatgt ccgtggggct attcttatcg gtatcgtagc
     1801 gaccacagtc cttggtattt ttatgggtgt tgttgattta agttccattg attggcaaac
     1861 gaattcgtta ggtaattcat ttaaagaatt aggaacaact ttcggtgcag catttggttc
     1921 tgaaggcatg caatctttat tcagtgattc ttccaagatt cctcaagtat tgatgacgat
     1981 catcgcattc agtttatctg atactttcga tacgatcgga acatttatcg gtacaggacg
     2041 ccgcacaggt attttctcaa aagaagacga gatcgcgttg gaagatggtc gtgggttcaa
     2101 aacaaaaatg gataaagcac tatttgccga tgcgatcgct acttctgtgg gggctatctt
     2161 tggtacatcg aatacaacaa cttatgtcga atctgcagct gggatcgggg ccggtggacg
     2221 tactggtttg acttcagtag tagtggcagt gctattcgca ttaagtagtt tattctctcc
     2281 actgatcgcc attgtaccaa atcaagcaac tgcgccagca ttgattttag ttggagtaat
     2341 gatgatggct tcttttgcag acatcaaatg gctagatatg gaagaagctt taccggcctt
     2401 ctttgcatcg atctttatgg gattgtgcta tagcatttcc tatgggattg cagcaggatt
     2461 tattttctat acaattgtga aagtaatcaa aggaaaatac aatcaagttt ctgttgcttt
     2521 gtggatcgtt gatattttat tcattatcaa cttcatcatt ctagcaacaa tttaactaaa
     2581 gagaagggat tggaacagta tttgttctga tctctttttg ttttacataa aaagaacgtt
     2641 acatataaaa tgacctttgc gggatttttc tctttttact ggcgagatcg ttgcttgttt
     2701 attcgaaaat aggtatgata aaagagacga aagagggatg atagatggag attaattgga
     2761 gaaaaaattt agtgattgcg tggattggct gttttttcac tggtgcaagt attagtttag
     2821 ttatgccatt cataccagtt tatgttgagc aactaggaac accaaaagat caaatcgaat
     2881 tgttttcggg actagcaatc tctgtgactg cttttgcatc tgccgtggtt gcaccaatct
     2941 ggggaaatct agctgatcga aaaggccgaa aactcatgat gatccgtgca gcagcaggga
     3001 tgacattaac aatgggatct ttggcttttg taccaaacgc gtattggctt ttgatcatgc
     3061 ggttttggaa tgggattttg tctggatata ttccaaatgc cacagcgatg attgcttcac
     3121 aggcacctag agaaaagagc ggatgggcgt taggaacatt gtctaccgga gcgattgctg
     3181 gaaatctgat cggaccttca atgggcggtg cactggctca gtggtttggt atggaaaatg
     3241 tattcttgat cacaggggct ttgttgatga tcacaacggt attgaccatt ttcttagtca
     3301 aagaagattt ccatccaatc gagaaaaaag atctgataag caccaaagaa attttttcaa
     3361 aaatggatca tctctctatt ttgatcggtc tcttcattac gaccttgatt ttacagatag
     3421 gaatcactac gatcagccct attttgacct tatatattcg tgaattgagc ggaagtacag
     3481 aaaatatcct ttttgtcagc ggcttgattg tttcgatagc tggtgtttcc gctgtctttt
     3541 cttcaccgaa actaggaaaa ctaggggata agattgggaa tcaaaaagtt ctaattggag
     3601 gactcatttt atcattttgc tgttatttac ctatggcatt cgtcactaca ccgctccaat
     3661 taggtatact tcgctttatt ttaggctttt caactggcgc tttgatgcct tctgtcaata
     3721 cactgatcag taagattacg cctcaagaag gagtcagccg aatctatagc tacaatcaga
     3781 tgtttagcaa ctttggacaa gttttaggtc ccatgctagg atcgacagtc gcgcatgctt
     3841 ataattacag tgctgttttt attgtgacaa gtttgtttgt tctgtcaaat attcttcttt
     3901 ctttattcaa ctttcgtaaa gttcttcgca gcagattata atggtggtga ggagtagaaa
     3961 ataaaaaaga gcttgagaaa tctcaagctc ttggctgttt ttttacgaat gggcagaggt
     4021 ttcttttctt ggcgcaactg caccaatcaa aaggataatg acacccgcaa tgaatgaaat
     4081 gattgttgtc aaagtaaaat catatgttcc gcttgttaat gcagcaccaa tataaccgac
     4141 tacttgacct agaacgacag cccagaataa tgtaacgata tatcgcataa agaacacctc
     4201 ttttctatct taattttacc agattttctt tgaatgtaaa gaaacgagac caaatctcaa
     4261 taaaatttga gttcttgcga aagaactcat tcctacagat tacaagcaag caaatgaagt
     4321 ggaataatca acttcagcgc ctgctatctt aatgaaagta aaaggatcaa accttttaac
     4381 gctagtgaat tttaacgaaa aaaaaggcgg aatgcaagat gtttttccca caactttata
     4441 caattacttc ttattctctt ttacaaagta cgatacgtat tcgagaatat gtacaagaag
     4501 caaaaaaaca aggctacact tcattagcca taacggataa agatgtctta tacggtgcac
     4561 ctgaattcta tcgtatttgt gtagaagaag gagtacagcc aatcattgga ttacatctta
     4621 gttatactta tgaagaaaaa aattatggct tgcttgcgta cgcaaaagat gaaataggtt
     4681 atcagcagct gatgaaactt tccagccgaa aaatgatcca agaaaaattg gaacttgcag
     4741 aaatgacaga aaccgaccat ctagcgtttg ttgttccggc aaatcattct gtttctgagg
     4801 ctttcaataa agaggataac tttttcggtc attggcagtt tttacttgaa aatgttttta
     4861 ctagaaattt ttatatcggc ttgacagaaa acacgcctga tcaattgcct gaatggtatc
     4921 agtatgtgat aaaagaaaat tattcgcttt gtgcattaca tcccatcgct agtttacaac
     4981 aagaagaact ttttgcactt gaagtgatga aacatatcaa agagggaagc caaatacctt
     5041 tagaaaattt atctgcatct ttaccactaa cagcaaatgt ctatcttctt tcagaacaag
     5101 aaatgatcaa acgattcgaa aaagcgggtc tttcccaagc tgtaataggc gcccagcgtt
     5161 tagctgaatc gatttcattt gaattccagt tccatcagaa attacttccg cattatccag
     5221 ttcctaatgg aaaacaagct ggagaatatt taagagagtt atgctattcg caagtggaac
     5281 gccgaatcac tgactataca aaggaatacc aagaacgttt ggactacgag ttatctgtca
     5341 tccatcaaat gggattcgat gattatttct tgatcgtatg ggatgtaatg gcttttgctc
     5401 atagaaacaa aatcgttacc ggtgcaggtc gtggttctgc tgcgggttca ttagtagcct
     5461 atgtgttaga aatcacagat gtggatccat tagaatatga tttgctgttc gaacgctttt
     5521 taaaccccga acgctttacg atgccagata tcgatttgga tattcctgac aatcgacgtg
     5581 aagaagtatt gaattatgtt cgagaaaagt atggacaata tcatatggca caaatcgcaa
     5641 catttggcac aatggcagca aaaatggttc ttagagatgc agctagagtg tttggtttat
     5701 cgcaaagtga agcaaaccgc tggtcaaaag caatacccaa tcaattgaaa atcacattga
     5761 cccaagctta taaaacttcg catcaattag tagaattagt tcaggcaagc gaaaaaaacc
     5821 aacttttatt caaaactgca gtgattttag aaggattgcc aagacatgtt tcgactcacg
     5881 cagcaggtgt agttatcagc gataagaatc tacttgaact agttccgctc caacgcggtt
     5941 ctgatgaagc ttttctgacc cagtatacga tgaatgaggt agaagcaatc ggtcttttga
     6001 aaatggactt tttaggacta cgcaacttat cgattattga ttttactttg aaagctgtta
     6061 agcgagtaga agggtatgag atccgattaa aagagatccc gctaaatgat gcaaaaacgc
     6121 tgctcttgtt tcaacgaggc gaaacctcag gagtatttca atttgaatct gctggtatcc
     6181 ggaacgtttt acgaagatta gatccagaaa acatcgaaga tattgccgca gtcaatgcat
     6241 tgtatcgacc aggccctatg caaaatatag ataccttcat tgccaggaag aaaggaaaag
     6301 aagccattcg ctacccagat gattcactga tcccgatttt gaaaaacaca tatggagtga
     6361 tcgtctatca ggaacaaatc atgcagatcg cctcgactat ggctggattt acattagggc
     6421 agtcagatat tctgcgacgg gcagtgagta aaaagaaaaa agacgtatta gatgaagaaa
     6481 agtcgcattt tgtatcagga gcattacaac agggatattc ggaaaaaaca gcagcgaccg
     6541 tatatgaata tatcgaaaaa tttgcaaact atggattcaa tcggtcacat gcatttgctt
     6601 attcattcgt gggattccaa atggcgtatc taaaagccca tcatccaggt gctttcttta
     6661 ccagcctgat gaattctgtt cggcataaca catcaaaatt gaaagaatat attgcagaag
     6721 cacgtaaaaa taaactcaaa ctttcctcgc cgtccattaa tcaaagtaat tccagttttg
     6781 agttggtcaa taaggaagaa atcagattcg gactgacagc gataaaaggt attcggcgtg
     6841 attttgtaga agatatatta aacgaaagaa aacaaaatgg cccgttccag tcagtggatc
     6901 aattcctcat acggatcgat aagcgttggc tgaaattaga gttactgcaa tcactgacag
     6961 cagtaggagt ttttgatgaa ttatctccta acaggaaaca attgatgctt gatctcgaag
     7021 gaaaaatcca aaatatcgtt tacagtggtg gaagtcttga cttgctggga atcatggcat
     7081 taaaagaaga agaagtcgct gactatacac tagaagaacg cttgaagctg gaagaggagt
     7141 acttaggtat ttatttgtca ggtcatcctg cagaagggtt tgatcgtctt cgtttagcta
     7201 aacaagttca gctgattaca gatatcgtcc ctaatcaacc agtcaattta ttagtgatga
     7261 tcaaggaagt tagagaaatt cggacaaaaa aaggagaact gatggccttt gttgaaggaa
     7321 ccgacagtag tggagaaatt tctgtcacag tttttccaac tctttatcgt aaatatcgta
     7381 atttgtttgc cgttgatcga gtgatctttg ttcaagggcg gagcgaaatc agcaaatata
     7441 atcaggaact gcaactaatt ggagaaagct ttgctgatcc taaccagtta gaagcccagt
     7501 atccttcaca aacttgctat ttgcgtatta cagaagaacg ggaagatccc gagataatga
     7561 aacaattaca agtgattttt cagaaacacc caggatatat accagtagtt atgtatcacg
     7621 aaaaaacgca acgaaaagta gttctgtcag atgcttattg ggtggatgac agcaagagta
     7681 taaagcggca acttatttat ctgcttggcg aagataatgt ggttttcaaa taacttacgg
     7741 taaaaaatac tacttgcttt catttttttt cattttttta tccgtaaatc aagacaagtg
     7801 agaaaaataa tgttagaatg ttagtcgtgg ttaacgcaaa aatggttgta aacctaagtc
     7861 atacttagga taaagtattt taatgaggtg aatgtttatt atgaaacgca tcggaatttt
     7921 gaccagtggc ggagacgcac ctggaatgaa tgcagctgtt cgtgccgttg ttcgtaaagg
     7981 tatttacgaa ggactggaag tatacgggat caattatggt tttgccggtt tagttgctgg
     8041 agatattcgt cgtcttgatg tggcagatgt aggtgacaag atccaacgtg gtggtacatt
     8101 cttgtattct gcacgttatc cagaatttgc aactgaagaa ggtcaattaa aaggaatcga
     8161 acaattgaaa aaattcggaa tcgaaggtct agtggttatc ggaggagacg gctcttatca
     8221 tggcgcaatg gctttgacaa aacgcggttt cccagcagta ggtattcctg gaacaatcga
     8281 taatgatatt cctgggactg atttcacaat cggttttgat acagcaatca atacagtact
     8341 agaatcaatt gaccgtattc gtgacacagc gacttctcat gttcgtacat tcgttatcga
     8401 agtaatggga cgcaatgcag gagacatcgc tttatggtca ggtgtggctg gcggagcgga
     8461 tgaaatcatc atcccagaac atgattttga tatggcttca gttgctaaaa aaatccaaga
     8521 aggccgcgat cgcgggaaga aacattgctt gatcatcttg gctgaaggtg taatgggcgg
     8581 aaatgaattc gctgagaaac tttcagaatt tggtgactat catacacgtg tatctatctt
     8641 gggacacgtt gtccgtggtg gagcaccaag cgcacgcgac cgcgtgttgg caagtaaatt
     8701 cggtgcttac gctgtcgaat tgcttcaaga aggaaaaggt ggattatgtg tcggtatcca
     8761 tgacaacgaa atcgttgcgt ctgacatcat tgatacactt gaaaacaaca aacataaacc
     8821 agacttatca ctatatgatc taaataattc actttcattt taagagtgaa agaaaccaag
     8881 ctatttaagc tgtgtacagc tttaaataaa caaaattgaa tgggagagtt ttttaaatga
     8941 aaaaaaccaa aatcgttagt acattaggac cagcaagtaa ctcagtagaa attatttctc
     9001 aattgattga atctggggca aatgtcttcc gctttaattt ttctcatggt gaccatgaag
     9061 aacaattatc acgtatgact atggtccgtg aagcagttaa aaagacagga aaagatgtcg
     9121 gtattctttt agatacaaaa ggagctgaaa tccgtacaac tgttcaaggc acaacagaag
     9181 ctgattttgg tcgtgcagga tacatcaaat ttgaagtagg agatcaaaca cgcatctcta
     9241 tggatcctga acatgtaggt tcaaaagaaa aaatcgcggt tacttaccca ggattatttg
     9301 acgatgttca cgttggcgga cacattttat ttgatgatgg tttgatcgat atgcaaatca
     9361 ttgaaaaaga cgaagcaaac cgtgaattag tcgtagaagt taaaaatgca ggtatgctag
     9421 gatcacgtaa aggggtaaat gcaccaggcg tttctattag tttgccaggt attactccaa
     9481 aagatgctga cgatattcgt tttggtttag acaacgatat cgactttatt gctgcaagtt
     9541 ttgtacgtaa agcacaagac gttctagata tccgcgaaat cttagaagaa aaagacatga
     9601 ctcatgttca aatcttccct aaaatcgaat ctcaagaagg tatcgacaac attgacgaaa
     9661 tcatcaaagt ttctgacggt gttatgattg cccgcggaga tatgggtgtt gaaatcccag
     9721 ctgaactagt accaatggtt caaaaacgca ttatcaaaaa atgtaatgct gctggtatcc
     9781 cagttatcac tgctacacaa atgttagaat caatgcaaga aaacccacgt ccaacacgtg
     9841 cggaagcttc tgacgttgct aacgctgtat ttgatggcac agatgcaaca atgctatctg
     9901 gtgaatctgc aaacggggac tacccagttg aagctgtttc aacaatggca cgtatcgacc
     9961 aagaagctga aaatgcatta tcagaattag gtacattcca attgaacgaa ttcgataaaa
    10021 cagatgtaac tgaaacaatc ggtttatctg tagctcgtgc tgcaaaaaat ctaggcgtga
    10081 aaacaatcgt tgctgcaact gaatcaggat acactgcaaa aatgatttca aaatatcgtc
    10141 cagatgcaga tatcttggct gttacttttg acgaacgcac aaaacgtggt ttgatgttaa
    10201 actggggcgt ttacccaaca gttgctgaaa aaccatcaac aactgatgaa atgtttgaac
    10261 tagcagctaa aaaagctgtt gaattaggtt tcgcatcaga aggcgattta atcttgatca
    10321 ctgctggtgt accagttggt gaacgcggaa caactaacgt gatgaaaatt caaatgattg
    10381 gttctaaatt attagaagct caaggcgttg gacaaaaatc tgtcgttgca aatgcagtta
    10441 ttgcttcatc tgctgaagaa gctgtaaaaa aagcaaaaga cggaatggtt ctagttgtac
    10501 catcaactga caaagaatat atgcctgcaa tcgaaaaagc agctgctgtt atcgttgaag
    10561 aaggcggatt gacttctcac gctgcagttg taggaattgc acaagatatt cctgtaatcg
    10621 ttggtgctaa aggcgcaaca acaacaatta cagaaggtga attgattacc gttgattcac
    10681 gtcgcggcat cgtttaccgt ggcgaaacaa cagctatcta atttagctta ataaaaaata
    10741 aaaacagctc ttcttttacg aagagctgtt tttttgtgct gtaacgaatt catggataac
    10801 ttggactact tgttcttgaa gaggcgtgac gatctgctgt gttcgttttg ccaatgaaat
    10861 caagaagcga ggctgaactt catctgaaag agggaggcaa actaaatgat cttcaggatg
    10921 gacagcaatc tctgccaaaa aaccgatacc cacattttct cggaccatac tctttaaaat
    10981 cgtcaagtca ttgctttgat aaacaacttt tggatgagta tgtgtttgtt tagaaagctt
    11041 agtgaatgct gcggggtgga cataatgttc gttcaatagt acaaactgtt catctgctat
    11101 atctttgaaa gagacagtat cctgcttgga aagaggatgt gtaggtggca cgacgatcat
    11161 gaaacgtttg tccaaaagta actctgtttc taaatattga tccacgattg gctgtgttga
    11221 gcctaataca gctaaatcga tcctcccttg tcggatcatc ccgtataagt cccgagagcc
    11281 tccatcggta atctcaattt gattcatcaa ttcatgcttg ataaagtaac ttgacagttt
    11341 aggaaagtat tcattgccga taataggagg catgccaaaa cgaagctttt tcttttgcaa
    11401 ctgagtgatt tcagctcttg cagtagaaat ctcttggaga atggtttgtg catggagaaa
    11461 cagctgcttt ccagaaggcg tgacgattaa ttcgtgatgc gatcgatctc ttgtaataag
    11521 tacggtgtca aactcttttt caagacgttg taatgcatat gtaatagtag gttggctcac
    11581 acggaaataa ttagccactt tcgtaaaatt tttttgtttg acgatttgga catagtattc
    11641 gatatctttc gtgttcatga agatcatccg ctcctttaat ggaataatga ttattgtaaa
    11701 tgattctgag gatgatagca aacagaggct ttctaataaa gatttttctg tttttttatg
    11761 aactgcaagg tgtcaagaaa atttcattga caacatgctt tttgccctgt ataattgctt
    11821 ttgttgctta ggagtgatga aaaatgaaat ggtctttatt ggaattgaga aaataccagg
    11881 agacaccgtt aacttttcat gagacgctcg acttgaaagc cgctctcatg aagcgagaca
    11941 atttaatact tgatgttgcg ccagtggaag tcgaaggttt ggtctcagtt gataagaaag
    12001 gctatatcgt tcattacact gtgcagacga ctttgacagt tccttcaaca cgttcactag
    12061 aacctgttga actgcccatg gatttttctg tagacgaagt attcatgaca gaagaacaat
    12121 tccaaagtag agatgaacaa atgtctgcgg atgagatttt gctaattgaa ggtccattat
    12181 tgaatttagc agagtcgatt gaagacaaca tcttattggc gattccaatg cgggtattga
    12241 caaaagaaga ggaagcagca acagaacttc caaaaggcaa tgattgggaa gttgtttccg
    12301 aagaagaata ccagcgcaga aaaatggaag aagccgagaa taaaattgat cctcgtcttg
    12361 caaaactatc tgaacttttt gattctaaat caaaagacga cgataacaag taagattgga
    12421 atatattgtg tctaatttag atacaagact ttacaaggag gtgtagcaaa atggcagtac
    12481 cagctagaag aacatcaaaa gctaaaaaag caaaacgtcg tacacactac aaattgacaa
    12541 tcaaagggtt aaacgaatgt ccaaactgtg gtgaaatgaa aaaaagccat cacgtatgtg
    12601 caaattgtgg ttactatgat ggtaaggacg taatgtcaaa agaagcttaa tacattttaa
    12661 ttagaaaatg taaaacctca aggctaacca tggagccttg aggtttattt ttttgtagtc
    12721 ggtaaataaa aaatatgttg ttctttagtt tgcaatgtag ccgtgttaag ctataatgta
    12781 agagattagg gagaaatccc gtatgtagga ggagttcata tgtcaaaaca acaaatcggc
    12841 gttgtcggta tggccgttat gggtaaaaat ctagccttga acatagaaag ccgcggctat
    12901 tcagtggctt tattcaatcg tacaggggct aaaacaaccg ctgtagtaga agaacaccca
    12961 gataaaaatt tcaaagcaac atatacaatc gaagaatttg tagaatctat cgagaaacca
    13021 cgtcggatct tgctaatggt caaagcagga ccggcaacag atgcaacgat ccaagagttg
    13081 cttcctcacc ttgataaagg cgatattttg attgacggag gaaatacatt ctttaaagat
    13141 acgatgcgtc gtaatgaaga gttagccaac tctggcatca actttatcgg tacaggcgtt
    13201 tccggtggtg aagaaggagc tttaaaagga ccttcaatca tgcctggtgg acaaaaagaa
    13261 gcctatgcgc tagttgcacc aatcttagag caaatttctg caaaagcaga agacgaagca
    13321 ccatgtgtca catatattgg cccaaatgga gccggacatt atgtgaaaat ggtacacaac
    13381 ggtattgagt atggagatat gcaactgatt gctgaatctt atgacttaat gaagaatatt
    13441 ttaaaccttt cagtagaaga aatggctgat atctttaaag aatggaatca aggcgaatta
    13501 gacagctatt tgatagaaat cactgctgac attctgacac gtaaagacga tgaaggaaca
    13561 ggtaaaccag tagtagatgt gatccttgat gcagctggga ataaaggaac aggtaaatgg
    13621 acaagccaaa gcgcgcttga cttaggtgtg ccacttccat tgatcactga atctgtattt
    13681 gcccgctata tttctgctta taaagaagaa cgcgtacaag caagcaagat tttatctcgt
    13741 acgaacgatt ttgagttcac gggagacaaa aaagaattgg tcgaaaaaat ccgagaagcg
    13801 ttgtatttca gtaaaatcat gagttatgcc caaggatttg ctcaattacg tgtcgcttca
    13861 aaagaatttg attgggactt gccatttggt gaaatcgcaa aaatctggcg cgctggatgt
    13921 atcatccgag ctcgattctt gcaaaaaatt acggatgcct atgacaaaaa tcctgagatc
    13981 gaaaatttat tgctagatga ttacttcgtt gaaatcacga aaaaatatca gcaatcagtc
    14041 agagacgtcg ttgccttggc tgtccaagct ggcgtacctg taccgacttt ctcatcagcc
    14101 atcgcttact tcgattcata cagagcagaa cgtctgcctg caaatataat ccaagcccaa
    14161 cgcgattact ttggcgcaca tacctatgaa cgtgtcgaca aagaaggaat cttccattac
    14221 tcatggtacc atgaagaata atagtctttc ggctgttagg aaatgagaaa ataaaaagag
    14281 gacgaaagag ctgaagtcga ttgttatgag tagacttcag ctctttttta aaattgctat
    14341 ccatgataaa atgactatag atttttaagc atattatcgg tataatgata gagtttttaa
    14401 aaagccagta gaatagaaag gataaaataa taaatgagca atattctaat cattgaagat
    14461 gaaaagaact tggcacgatt tgtcgagcta gagttgaagc atgaagggta taacgcagaa
    14521 gtccactaca acggccgaac tggtttagat gcggcattaa ataatgagtg ggatgccata
    14581 ttgttggatc tgatgctccc agaattgaac ggtttagaag tctgcagacg tgtacgccaa
    14641 gtcaaaaata caccaatcat tatgatgact gcaagagatt ctgtgatcga tcgtgtatct
    14701 ggacttgacc acggagcaga tgactacatc gtcaaaccat ttgctatcga agaattatta
    14761 gcacgtcttc gtgcattgtt gcgtcgaatc gatattgaag gcgataaaaa tgtggctaaa
    14821 caaactacta ttacttatcg cgatttgact atcgaaaaag aaaaccgtgt cgtacgtcgc
    14881 ggaaatgaag taattgaact aacaaaaaga gaatacgagt tgctgcttac tttaatggaa
    14941 aacgtgaacg tggtattagc acgtgacgtt ttactaaata aagtgtgggg atacgaaaca
    15001 gaagttgaaa caaacgtagt ggacgtatat attcgttatc ttcgcaacaa aattgacgtt
    15061 cccggggagg aaagctatat ccaaactgta cgcggaacag gttatgtgat gcgctcgtga
    15121 taaagccgaa aaaatcggaa aaaagagaac tgaaagggcc ctccttgaca atcaagtggg
    15181 cctttgcgag ttctttcttc atattcgttg tgtttacaat tttcgctgtc attacctata
    15241 aatcatctat caatctgatt gtggcaaaag aaagaaacaa tgtagagcgt acgatttcag
    15301 aagtagcttc tcgtttggct aactcggatg aagaactgac attagtaaat acgtatcgta
    15361 atctgacgaa agcgacaaat gacggagatg aggtcgtaga tcatacttca ctggtcgaag
    15421 gaaacttaat gaagatcgat tcctttatag ctgagctagg gcagccatca atggatcttt
    15481 atgtttatga tttggacgag aacttgattt ttaaaaccca tgaaaacagt cgaaacctga
    15541 ttcagactac acgtaaagtt ccaacgatcg ttacactaga aggaaaaact ggctttttat
    15601 ctatccagcc tatatattct aaaggtacaa gagaaaagat cggctatgcg caaagcttct
    15661 atgaattatc ttctttctat gatattcgaa ataagctatt attgactctt attgttttag
    15721 aagttgtttc tttgatctta agtagtattt taggtttctt tttatcttct tatttcttaa
    15781 aaccactcaa ggtactcaga gatacaatgg atactatacg taaagatccg caatcagata
    15841 tccacatgcc tgaaatcgac acaaatgatg aattggcaga tttagctgaa atattcaatg
    15901 agatgcttga ccgtatgcgt ttgtatattg aacaacaaga gcaattcgtg gaagacgtat
    15961 ctcatgagtt aaggacacct gttgcaatta ttgaagggca tcttagtctg ctaaatcgtt
    16021 gggggaaaga tgatcctgag atattagaag aatcattaag cgccagcatg caagaaatta
    16081 gccgtatgaa aagcttagtt caagagatgc tagacttatc aagagcagaa caagtagatg
    16141 ttcattatgc gaatgaaaca actaaaggaa aagaagtcac ctatcaagtt tataataatt
    16201 tcaagatatt atatccagac tatgtgatca ctttagatga tgatttgaca aaagaagtga
    16261 ccctgcaaat ttatcgtaat cactttgaac aattaatcat tatcatattg gataacgcag
    16321 taaagtattc aactacacga aaagaagtcc atatctctat ttcttccact ctgaatgaat
    16381 ttgagatcgc gattcaggac tttggcgaag gaatacccaa agaagacctt aataagatct
    16441 tcaatcgttt ttatcgagtg gataaagcaa gagctagaac gaagggtgga aatggtctgg
    16501 ggttgtctat cgctaaacaa ctggttgaaa actataaagg acgtatctta gcagaaagtg
    16561 tagtagggca agggacaatt tttagaatct ttattcctat cgcaaaggca gaagacaagt
    16621 aaagcatgtg ctttacttgt ttttttatat atccaacaaa gaataaggta caaaatacaa
    16681 gcaagttaga aattcaggaa tgtcattata aaaaaaacta gcgaacaatt aaatagaata
    16741 acatccgtta attaaacgta agtagctttt agatgaacga aaaaacaatg aaatgctgta
    16801 atattcgtgt ttaaaaataa taaataaaaa tagggaattt tctattgcaa ttttataaag
    16861 agattgctat attattattt gttctaaatg attcctttaa ggtgtcacta aaaattataa
    16921 aaaatagggt tgacgcactt ttgatgtcat gttataataa cgaagtcgtt tggatgaggt
    16981 agctaataaa gcttgatttt atcgaaaaaa acttcgaaaa agttgttgac aaataacaat
    17041 aaagatgata tgataatcaa gtcgctgcta atgagtgaca aagacgttta gaaaaaataa
    17101 acaaagaagt tgttgacatt ctcttctgaa tctgataaga ttaaagagtt gttgaaacaa
    17161 aaaga
//
LOCUS       DAZKCW010000051        16569 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000051 DAZKCW010000000
VERSION     DAZKCW010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.051"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            719..1522
                     /locus_tag="ACG84Z_002034"
     CDS             719..1522
                     /locus_tag="ACG84Z_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFP9162846.1"
                     /translation="MSQEVTENVIDNDVDLVSDQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNVFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQQETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFESFDYEKIYAKKGRKVDRLRFTFSEPESNLPSISMHNWLEED"
     gene            2129..2584
                     /locus_tag="ACG84Z_002035"
     CDS             2129..2584
                     /locus_tag="ACG84Z_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162847.1"
                     /translation="MDAINWHEFVNYMEKLLDDLKSFSIADAVKHGLPVSTTMKMRGL
                     KVPDEIIKLRTKTIIETAKIVDSMNLDLKGKKTTYEKDFVRFLKNVIGKYLGKKSFTE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIVEYLENKEQKKGTKKGR"
     gene            2703..3761
                     /locus_tag="ACG84Z_002036"
     CDS             2703..3761
                     /locus_tag="ACG84Z_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HFP9162848.1"
                     /translation="MEKDVNSASTKDQYNIIGGLLGDKDKRTRHGLRIMLATFLGVFL
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLTFARSGAEITISDVWTDKTRDVTVVKLG
                     YSGNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNESDSVTKALSQYSMNDVDNEGVISFGKKAKPVN
                     TPDNINFRINPYSDTTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKTINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            3803..5752
                     /locus_tag="ACG84Z_002037"
     CDS             3803..5752
                     /locus_tag="ACG84Z_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9162849.1"
                     /translation="MENSTEFFKNIQTEFNHALTLMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAKRQRQEGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TIIPRLKEYERILKSEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPEASLK
                     LSKKIPDELLEEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDIAKLEEELKSIKGQPVAVYTVTMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRKLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVNDTVSLSNTILFATTNAGAE
                     MYDSMNRYSSLSRVANQENSNEYSTELKREYRKVALEIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAHNEILKSAELVRKHLNVDLRLPPQKKHFYGQEFYADDLSMHLV
                     FDRASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSKAGGFEGKGDT
                     DAEIIAKPSIAESKENKFVFSVGGV"
     gene            5755..9444
                     /locus_tag="ACG84Z_002038"
     CDS             5755..9444
                     /locus_tag="ACG84Z_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3659 domain-containing protein"
                     /protein_id="HFP9162850.1"
                     /translation="MKFKKSLLQNRKIKRWVVRGLVIVGALAVTLGAPFGMNDPTSDD
                     QGNKQETVANTNVAYAESKPAEKGVWTLYARILMGDKEVNDSATKTGQMNLLGQGGIS
                     ADFPYSDISKQGNAIAGGNAGTQLASTLATYNYYGYIETVSGNAIASQASSFIGGIGR
                     TLGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGKGGSDVSNPVAKALTSLL
                     NNLGLNNQLFKAIASLSMLFFTAILGYQGMKLLSKEGVNSKGLSPVLEKWIVRIFVLF
                     VFLPVAGSLLGVYINGIQSAKEDGKLPTNVVGDYIINTRLWASTQNLAPSSDTGGNVP
                     NGKPTSEIKFVDTDYEPSKKSEMIRMINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NVNTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGNAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTTNNFDATQPWGVANNATFSTQSVALMLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFVRVWEVVLTGSLAAGAGVMAISLGVVTTSLIGLQLPIFLITFVRAFGDTAV
                     GFIPNTLLGDGVANIVRSAMVLGVGYLLVFKKGEKVNNNLINMLIGLPLEVAFGFDER
                     AKLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGRGSVKDMVAGGLGAVGAQGIAD
                     RLNNMGDSNADAKTIADKVVPETPASVPFNGGGVGGTINNTSFKDLVRQDQLRNNSQQ
                     YSDHLGRMVDEKGNFVDENGEVLKDSKFGKDAKGNFIDAKGRLVDEDGNLIDTNGKPL
                     EDNEDGNIGMDSQGRLIDDKGRLVDDEGNLVDENGRKLLNGDFGQDVNGRLVDDKGRL
                     VDEDGNLVDEFGKKLGKHSNGYNVNGDTVDEDGNIIDSRDALVADRNKELEQQQHTPI
                     AVAIPDDESDEVILDQAHQGLREEAKDKVVSDQAQEELKNKSNGEDVSNQYHQTAGNV
                     PVEGQSNELHNNFDNVADRNDTVLKEKESLRQETDKDQSKLKKTTIPTPIGSTVPKVN
                     QANDSETNTGLGMAKDNQSIREPKKTTESSKSNKSKSTSNKTGKSKEPSKAKSAVEYL
                     SKTGKNVYTSADKALAKAPKGSLAGMTYEAKNEAIKLGKGTAKVAKVTAKGATKTGKA
                     VKKSTMSVKDYIAKYSEQKPTDKKS"
     gene            9855..10193
                     /locus_tag="ACG84Z_002039"
     CDS             9855..10193
                     /locus_tag="ACG84Z_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162851.1"
                     /translation="MFDSIKNLVSGMTPEMKTLVQAILYLMATFFALKPGFTAMKHFG
                     DAKWGEGLKYVGAVVAIFIIPVITTVMLLTMGTKTGNDLNQKANMISALIPVVGIYLV
                     TKFPKEEQLG"
     gene            10320..10541
                     /locus_tag="ACG84Z_002040"
     CDS             10320..10541
                     /locus_tag="ACG84Z_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162852.1"
                     /translation="MLVHANEVLTSGFKGTDLAKIMNMNVNQFYDYRNGNKKIEKARL
                     ETLIKFEKAYLYVLDKQKRTIDRKKGVLQ"
     gene            10541..12706
                     /locus_tag="ACG84Z_002041"
     CDS             10541..12706
                     /locus_tag="ACG84Z_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162853.1"
                     /translation="MAKFKDITESINYVAETVPVVVLSLKPQLLEVYQKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYVVIEDVQKLSSEEFPDEEDAILDSEKYVVLLKSSLN
                     YVVDLPEKFKEKLLAGVRFMDSNGQLLVIPDDPNMFEREVEEATDFYSAVDQLEVATK
                     GLERIAETFNSSDAVEFEAVAEAETEAVPDEEEALFEDNDEATEAGNQEASIEETQTE
                     TYQQPKIDEKPESQSDKENYVYEAEKIVSESDVPKNLDADLLEKDFEQIIANKFQPVV
                     LDEVSDPVDLNEEMRSIAELKPLLFLAKESMNARISIANNKINSELNKTKEQLLLKGK
                     QMLADELLRIEEATSLSGQNQFTNTLSVAKESYEAEASKIDDLVMEKSSIIRKDYDMA
                     KQAYLEAELKKLEQRYDAEHLPEVKQQEDEFRKATEESLDQQYQEAIESIKNDALKQN
                     QEAKEVVVERIINSLKPEIEKSLTEVQEKTLEIVEKTKAENEAEFHDTKEKTTDVVVK
                     YFANKEEVEKLVAKDTNELESKLVAQQNIIEDYKNRVKEFKDLADGYKLNSQKLTEQS
                     EALREDLSRARNDLSQMAEKTKSLVVTTENQTESKRDFTSKKMATIIAVSAMACGTIL
                     GSSYFISHNHQEAQAQTETSISRVENSLGAKTASTSTTDNNYEATPTTEFKVGEDVVI
                     SIDGKTTKAEVLSIDGDKAVVKAPDGNQYKIQAHLTEKN"
     gene            12718..12948
                     /locus_tag="ACG84Z_002042"
     CDS             12718..12948
                     /locus_tag="ACG84Z_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFP9162854.1"
                     /translation="MREENIVYPVIENQSNTKSSQLLQEVQVVYPVNELPQTNETVSK
                     SISLIGLLIVATALTVGVYRKLKVKGSISDGR"
     gene            12938..13804
                     /locus_tag="ACG84Z_002043"
     CDS             12938..13804
                     /locus_tag="ACG84Z_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162855.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVDWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLRFIFIPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNTARVTMGKKKPFRGTEILKVRQDGTIMYRDGSVALMFNLDGATSLTAFP
                     EEIIAQEGKSIQYQNARDRSLAEIKITSSQPQNTERQIRNMKVQKRNAKSNKAVFDIV
                     DQQERFVSEYIDGVKTTVIQYLILKSQSQMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSEIYALK"
     gene            13822..15780
                     /locus_tag="ACG84Z_002044"
     CDS             13822..15780
                     /locus_tag="ACG84Z_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162856.1"
                     /translation="MELMSRSKLLNFRKKKHKKEQNADSSKAVNNTYVSDLTSLVGYQ
                     FTPSYIRTGNRWGTIVKLVNTYGMNRNYEFGWMVKAIPEVKVEGVKAYLIEADKPVSQ
                     KDQQEIMHENVGGSTNSYENNLNDKNSDAEINKTVMRIIDLNTASLLDSTANKIIDWK
                     LEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSFGGDQRDLFDRLLSEPVGSVYEY
                     TSMSSDFAGNDHAIRKGLDDADGWAIGTMSTSYASGVAFMAMDRSFKGKVLVASHKDA
                     TIKGYSEEISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGETFVAKPSLNSV
                     IEKINLAEEGLNSLELFGDRKDIGDLYRRNLDKLTQIFYLLADRELNPATRVLLKKEL
                     GNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEIDRII
                     VLKDTLRTALDSFSKMFNQRTTLKEIGKSDKLQFYYNLSDLRTEINVMEAQFLNTFDF
                     ITSQAKKGDIVMIHGFDRLSVETVGLIKKRLTMLEEDGVRLAFLFDTIGSGESKDGIE
                     TADIFNTDGKIYQSFESDFNYTIIGKMTSEELMKYEKKVAPARKGEDDQKLSVDLRQY
                     LTSGRSNKFQIRRPADLTNNFVIGEFII"
     gene            15868..16476
                     /locus_tag="ACG84Z_002045"
     CDS             15868..16476
                     /locus_tag="ACG84Z_002045"
                     /inference="COORDINATES: protein motif:HMM:NF012234.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9162857.1"
                     /translation="MKSNIKIIAGDKMKEKENLVWYFNRNPHMLITGRTATGKTYLLK
                     RMADYLSQVGIVSASFDKTEFEEILSSSRKEMEDRFEYIKENRFKMFDVSYSDLDMKP
                     YFVLIDELDSRLLLLEKENPLAYNYLLLIIKDIVLKGRVVGVFFIAVRQGKQPLLESI
                     EDNMLTRIFLGDSKGNGTICFDGNTKKFQTELVTEDFFSVDC"
BASE COUNT         6028 a         2434 c         3424 g         4683 t
ORIGIN      
        1 tcggaatacc acatcgcttt ttgtccatgt ttgcatcgct ttttgtccac attcacatcg
       61 ctttttgtcc atgttcgcat cgctttatgt ccaccctaaa atctatttaa gattgatata
      121 aagccttttt ggaggttgct aaagttttaa agattaaaat atatattata aatataaata
      181 aaaggggaag ctgaagcttc ctccttttcc tttttttcaa ttattcaaaa ttacacaagc
      241 aaaataaatt gctagatagt gttagttttt gttttaaggt ttttaatttt tgagattttg
      301 aaataagaga ggaggaatcc tcctttatta aatatctgtt aatatatctg ttaaatatct
      361 gttaatatat ctgttagggg ggtcttaaac ccttgggaga gtaagtattg aaggggtatg
      421 aaggtaacac ttttggacag taaaggtaac aaaagtggac agtaagggta acatttttgg
      481 acagtaaagg taacaaaagt ggacatttga ggtatcaaat caggataaga cgttaccttc
      541 ggttttcttg atttggaaat ctaaaaagta gaaaactaga ttagtaacaa atctttgttg
      601 actgttacct ttagttgtga tttaatttag gtaacaagca gaaaaaaagc gtttccttta
      661 atttagtacc aaattaacat gattaaaggg atgcaacaag aagattggag agtaatcaat
      721 gtctcaagaa gttaccgaaa acgttattga taatgatgta gatttagtat cagatcaaac
      781 aaatgcaatt gttcgttata acaatggttt gaacacaaca gctttgcgag gatttaaacc
      841 tgtagaaatg gatgtgtttt gggctatttt atcaaaaatg aaacgtcaag gaacagcaga
      901 agtaactttt gatttcaacg tctttcgtta tttggtcaaa tacgacagaa gagaaaagga
      961 cagtttttat tctgtgttaa aagctttgag tgacaaacta ggtactttaa cctaccgctt
     1021 tgaagattca gatgtctatg aacagctgtg gctttttcaa aaattccgaa tagataaaca
     1081 gcaagaaaca gttacaatca aggcaaatga ggagtttgaa tttatcttaa attcaattgg
     1141 caaaaacttt actcgttttg aacttgataa ctttacaaaa ctaagaagta gctacacaaa
     1201 agagctgtat cgtcatctca tgcaatatag aaataaagag tggcgaaatg gctattgggt
     1261 agtcaaagtt gaagatttta gaagagcgtt aagtattcct tcaagttaca gaatgacaaa
     1321 tattgacaaa agaatattag agcaggcgaa agaagaattt ttagctcctg atgaaaatgg
     1381 tatacaggta tttgaatctt ttgattatga aaaaatctat gcgaagaaag gaagaaaagt
     1441 tgatcggctc agattcactt ttagtgaacc agaatcaaac ttgccatcca tttcaatgca
     1501 taattggtta gaagaagact gaaaagaagc aggttgtaat tttaatacaa cctgcttctt
     1561 ttgaaaaaag tatgggtaac acttttggac aataaatgca agaagttttt ttgtgaccaa
     1621 actttatatt agattactgt gattttgtgt gttagaaaag ccctgataga aaagcaaatt
     1681 caaacacttt ttaatatgta tgggtaacac ttttggacat gtcaataata aatatatttt
     1741 ctttcgtctt ttgcctaact aaaggtaaca cttttggaca gtatagtttt gtaaactaat
     1801 tagatcgggt ttaatgggat atatcttagc atttatgtaa gaatgaaggt aacattaatg
     1861 gacatgtcaa ctgtttgaac aaaaaaatat agaatatttg gatctgattt ttcatttttc
     1921 caaacgttaa aaaatagtta gttattttat taatagatag tcatccttaa tgtttgaaat
     1981 agcagaaaat aagatattgt ttgataaatg ttgttgttat aaggaaaact tgaatttgtt
     2041 aattgattta tttatgttat tatgatacta taataacata aatgtgttac gcccgaacct
     2101 cattttacaa aaatgaaggg gtgagacaat ggatgctatt aattggcatg aatttgttaa
     2161 ctatatggag aaactactag atgatctgaa aagttttagc attgctgatg ccgtaaaaca
     2221 tgggttgcca gttagtacaa cgatgaaaat gcgagggttg aaggttccgg atgaaattat
     2281 caagctgagg actaaaacaa tcattgaaac tgcaaaaatt gttgacagta tgaaccttga
     2341 tttgaaaggc aaaaaaacaa cttatgagaa agactttgta cgttttttaa aaaatgttat
     2401 cggaaaatat ctagggaaaa agtcttttac tgaattgaga gacgaagaga ttgtaccaac
     2461 tccaatggtt agcaaaattc gcaaaaacaa agccgaggga aattactatc ttggcacaat
     2521 agcaaaaatc gttgagtatt tggaaaataa agagcaaaag aaaggaacga agaaaggaag
     2581 atagttcgtg tgataaatat gaatagggaa gaatgtaccg aaatgataaa aaaacccgaa
     2641 cctagaatta ccgaaaaact gactgattgc ttgctctttt acgaaagggg gcaggcaaac
     2701 taatggaaaa agatgtcaat tcagcatcca ctaaagatca atacaatatc attggaggat
     2761 tacttggtga taaggataag agaacacgtc atggattacg cattatgctt gcgacatttc
     2821 taggggtgtt tcttttatta acaggcttgg gtagctacat ttatcaatta ggaaactata
     2881 attattatct tgtcaacaat acaacaccaa tcggctcatc attgacgttt gctcgatcag
     2941 gagcagagat cactatctca gatgtttgga cagataaaac tagagatgta acggtggtca
     3001 aacttggtta ctcaggaaac gcaagaaaat tgctatctac acaaggtaaa aattataact
     3061 tgtatatggc aacaaaagaa aaagatcgtc ctaagaagct tgaaatgagt tatgggatgt
     3121 taagtaccga tggtgatgct ttcttgttcc taaaaggtaa attagatgaa agagcttatc
     3181 aagtttttat tgctaaccaa gtatcactaa tttcaggtga tgatacagct gatgatgata
     3241 ccaaagtcaa tgtgaatgaa tcagattcag tcaccaaggc actttctcaa tattctatga
     3301 atgatgttga taatgaagga gtaatttctt ttgggaaaaa agcaaaacca gttaatactc
     3361 ctgataatat caatttcaga ataaatccat actcagatac aactaacgta tatcaaggaa
     3421 gcttccttac caaagatggc gatattgatt actcaaaagt tgtagctgtg acaagtaaga
     3481 ataatgttgt aaataagcta gaagaccagt taaatgcttc aaatactaac atcaagaaaa
     3541 tcgaagccac aaaagctgag tatcttgaac gtttacaaca aaatcctgac gataaagatt
     3601 cgcaagaaag tattcgtcaa ctagacagtc gaatggagac cgaaattaaa acaatcaatg
     3661 atacacaaaa attgattgat cagtacaaaa atgctgactt taacaaagat tcttttggag
     3721 atatgaagac aacatttaag tacctaaccc tgactgacta gaaacaaatt attcttattt
     3781 tagaggaagt gaacacaaac agatggaaaa tagtaccgag ttctttaaaa atattcaaac
     3841 cgaattcaat catgctctca cactaatgaa accaccgaaa cataagttag tggggcgtga
     3901 tgacgaactc catgagttgt cactgatctt aaatagaccg gaaacaccac aagctatctt
     3961 gttaggtgaa gcaggaacag gtaaaacagc actggcaagt gaatgggcta aaagacagcg
     4021 acaagagggg aagaaagtac aagtatataa attatcaatc ggacaattgc gagttggagg
     4081 agatgacgtc ctccaaacac gtttggaaac tataattcca agattgaagg aatacgaacg
     4141 aattttaaaa tccgaggaca aagataatga atttgtcctc tttatagatg aatttcataa
     4201 agttgtcagt tcatttggga gcggtaataa aattggggga gattcgctga aggaaccttt
     4261 agcaaatgaa tcacttcagt tgataaccgc tacaactaga aaagaatatg aaaactatat
     4321 caaacgagat gatgctttag gtagacgact acaaccgtta gaactcaacg aattaaaaag
     4381 tgatgtcgtt gtcgatatac taagacaatg gttgaataca tcatctgtca aagatgatcc
     4441 tgaagcttcc ttgaaattat ccaaaaagat tcctgatgaa ttgcttgaag aaatcgtaca
     4501 agcaaacaag ctttatcgtg aggatttatc cgaaccggct aaatcaattg ccgtaatgga
     4561 agatttgatt gcgaaggatc gtgtagatgg caatgcgtat aatcgagaaa gcctgttaca
     4621 aatatttgga aaatataata ttcaactaga ttctgatttt gatatagcaa aattggaaga
     4681 ggagctaaag tccattaaag ggcaaccagt agcggtatat acggtcacga tgttgtttaa
     4741 acgaatgaaa cttggatttg atcgttttaa agggcgaaag caaccaaaag caacggcttt
     4801 gtttacagga tcaacagggg tcggtaaaac tgcgatggct aaagctgtag caagagggct
     4861 atacggtgat gaaaataaag tccttttagt aaatatgcca gactataaaa ctaaagatga
     4921 tgctatgcgg tttagaaagc ttatcggaac acatgtccgg catgatccat cagcaatcat
     4981 tgtttgtgat gaatatgaaa aagcaggcgt agaaacactt gatgcctttt tatctattct
     5041 agatgaagga agaatcagtt ttactgaaag aggatgggat gatcgagaag ttaatgatac
     5101 cgtctcactt tcaaatacga ttttatttgc gacaacgaac gcaggggctg agatgtacga
     5161 ttcgatgaac cgatacagct cactatctcg tgttgctaat caggaaaatt caaatgagta
     5221 cagcactgag cttaaaagag agtatcgaaa ggtagcatta gagattaaac aagctctaat
     5281 tggtgaaggt ctaaaacccg aagtcatcaa ccgatttgga cggattgttc cattttgggc
     5341 tttatcggaa caaactcttt tggaaattgc acacaatgaa atattgaaaa gtgctgaatt
     5401 ggtaagaaaa cacttaaacg tagacttacg ccttccacca cagaaaaaac atttctatgg
     5461 tcaagaattt tatgcagatg atctctccat gcacttagtt tttgatagag cttcacaaga
     5521 agattctaaa tcagggggtg caagaaatat cttgcatctg gtcgaatcag aatttgaaga
     5581 agcaattact gaagcaataa ttacctatcc taacgccaaa atatttgacg ttaaattgag
     5641 caaagcagga gggtttgaag ggaaaggcga tacggatgca gaaattatcg ctaaaccttc
     5701 catcgctgaa agtaaagaaa acaagtttgt gttttcggtt ggaggggtgt agctatgaaa
     5761 tttaaaaagt ctttacttca aaatcgtaaa attaagcgat gggttgtaag aggtttagtt
     5821 atcgtggggg cacttgcagt tactttaggc gctccatttg gaatgaatga tccaacgtct
     5881 gatgatcaag gaaataaaca agaaacagtt gcaaatacga atgtggctta tgctgaaagt
     5941 aaaccggcag aaaaaggggt atggacacta tatgctcgta tcctgatggg agataaagag
     6001 gtcaatgata gtgccactaa aactggtcaa atgaatttac ttggtcaagg aggtattagt
     6061 gctgactttc cttattctga tatttccaaa caaggtaatg caattgccgg tggtaacgca
     6121 ggtacgcaat tagcatcaac cttagcgact tataattact atgggtatat cgaaacagtt
     6181 tcaggaaatg cgattgcaag tcaggcatcc tcttttattg gtggtatcgg tagaacgctt
     6241 ggcagtttta tcggatcaat tagcttgata ctttctaata ttgctgaatc catcaatgaa
     6301 ctccttggaa aatttttcat gagtatgaat atattttcac ttatgggttg gggtaaaggt
     6361 ggatcggatg tttctaatcc ggtagctaag gcgttaacta gcttacttaa taatttggga
     6421 ttaaacaatc aattatttaa agcgatagca agcttatcta tgctcttttt tacagcaata
     6481 ctaggctatc aaggaatgaa actgttgtcg aaagagggtg ttaactcaaa gggattatca
     6541 ccagtacttg aaaaatggat tgttcgtatt tttgtattgt ttgtttttct accagttgca
     6601 ggatcgttat tgggagttta tatcaatggt attcagtcag caaaagaaga tggaaaatta
     6661 ccaacaaatg ttgttggtga ttacatcatt aatacaagac tttgggcttc tactcaaaat
     6721 cttgctccat catccgatac tggtgggaat gtgccaaacg gaaaaccaac atctgaaatt
     6781 aaatttgttg acactgacta tgaaccatct aaaaaatcag aaatgatcag aatgatcaat
     6841 actagcagtt acgctagaca aaataatgat ctagattcca attcagtcgg catggcattg
     6901 ttaaaagaat ggtcaagtaa tgatacgttt aatgtcaata cttatgccgg tgatgtgaat
     6961 gtagctgaaa atgatgctta tatgggaaga gcgcctgctg tttggacagg ctataattta
     7021 ggggatggaa aagaaggaaa tgcaattaag aaacctacca atttaaatgg ttatatttgg
     7081 tcagctaatc aaaacgttac agacgacaac cgcaagcctg atggaaaagg aacaacgaat
     7141 aactttgatg ctactcaacc ttggggtgtt gctaacaatg caacgtttag cacacagtcg
     7201 gtagcgttga tgctccaatc agcactggat acatcagggg ctaagtttta tgcgtataat
     7261 atcgctccat caggaattca aggtagtgct aagaatatgt caacagtaaa gacagaatgg
     7321 cgtacagctt ctttagttgg tcatggagct atgggtaaat tcggctcatg gttagcgatg
     7381 aacgctgaat caatcgtatt agcagtgctt tatctagctt gtgcttgggc gatgtttaac
     7441 gttaatattg taaaagcctt caaacgtgag tttgtgcgag tttgggaagt agtcttaaca
     7501 gggtctcttg ccgcaggagc aggggttatg gcaatctcat taggagtcgt aaccacatct
     7561 cttatcggat tacaattacc tatttttctg atcacctttg ttcgtgcatt tggagatacg
     7621 gctgtaggat tcatccctaa cacattactt ggtgatggtg tagcaaatat tgtacgatcc
     7681 gctatggtct taggcgtagg ataccttcta gtctttaaga aaggtgaaaa ggttaataat
     7741 aatttgatta atatgcttat tggattacca cttgaagtag cgtttggttt tgacgaacgt
     7801 gctaagttat tatttggcaa tagaaatgat gctgttcgag ttgtggatgg cgtttctaaa
     7861 gcaatcaaaa aaagccaagg ggctaaaaat ccttattatg atggtggcag aggatcagta
     7921 aaagatatgg tcgcaggagg acttggagca gtcggagcgc aaggaattgc tgatcgtttg
     7981 aacaatatgg gagacagcaa tgctgatgct aagacaatcg ctgataaagt tgttcctgaa
     8041 acgcctgctt cagtaccatt taatggtggc ggagttggtg gaacaatcaa taatacctct
     8101 ttcaaagatt tagttcgtca agatcaatta cgtaataact cgcaacaata tagcgatcat
     8161 ctaggacgga tggttgatga aaaaggaaac tttgtcgatg aaaatggtga agtattaaaa
     8221 gacagtaaat ttggtaaaga tgccaaagga aactttattg atgccaaagg gcgtttggtc
     8281 gatgaagatg gaaatttgat agatacaaac ggtaaaccat tggaagacaa tgaagatgga
     8341 aacatcggta tggatagcca aggacgttta attgatgaca aagggcgctt ggtcgatgac
     8401 gaaggaaacc ttgttgatga aaacggacgt aaattactta acggtgattt tgggcaggat
     8461 gtcaatggtc gtctagttga tgataaagga cgattagttg atgaagacgg aaatctggtc
     8521 gatgagtttg gtaagaaact tggaaaacac agtaacggtt ataacgtaaa tggcgataca
     8581 gtcgatgaag atggaaacat cattgattca agagatgctc ttgtagcaga tcgaaataaa
     8641 gaactcgaac aacaacagca tacaccaatt gcggttgcaa tccctgatga tgaaagcgat
     8701 gaagttattt tagatcaagc acatcaaggg ttaagagaag aagcaaagga taaagttgtt
     8761 tcagatcaag cacaagaaga gctaaaaaat aaatcgaatg gtgaagatgt ttcaaaccaa
     8821 tatcatcaaa cggctggaaa tgtacctgtt gaaggtcagt ctaatgagct tcacaacaac
     8881 tttgataatg ttgctgatcg gaatgataca gtcttaaaag aaaaagaatc attaagacaa
     8941 gaaacagata aagaccaatc aaaattgaag aaaacaacta ttcctactcc tattggttca
     9001 acagttccga aggtcaatca agctaacgat tctgaaacaa acactgggtt aggaatggcg
     9061 aaagacaatc aatccattag agaacctaaa aagacgactg aaagtagcaa gtcgaacaag
     9121 tctaaatcta cttcaaataa gacagggaaa tctaaggaac catctaaagc taaatcagca
     9181 gtagaatatc tatctaaaac tggtaagaac gtgtatactt cagcagataa agctttagca
     9241 aaagcgccaa aaggaagctt agcaggaatg acctatgaag ctaagaacga agctatcaaa
     9301 ttaggtaaag gaactgctaa agttgccaaa gtaactgcta aaggagcaac taaaactggt
     9361 aaagcagtga agaaatctac gatgtcggtg aaagattata ttgcaaaata tagcgaacaa
     9421 aaaccaaccg ataaaaagtc ttaagaagaa taaaaagagg gagcattaat atgctccttc
     9481 ttttttgttc ttctcttcaa ggggaatgtc aagaaaaact taattgtctt caaaaatttc
     9541 ttttttattt ggtagtaaat ctatgaaata tttgcttttt tagttatcgg ttaataagag
     9601 ggcttatgct agttagttaa aatcgggtaa ctagtcatta aatgctgata aataagcaat
     9661 ttttacgaaa aaaaaagaaa aaaatttgag ggaaaatacc tttcaatcta caaaaattta
     9721 tgttattatg ataacataaa gatgtaaata tcgaagcgtc ttttctgtat tccgatcatt
     9781 gacaagtgaa cagagaaaag tttgcgatga tataattatc ttgtgaaaaa taatcgaaag
     9841 gaaggattta taatatgttt gattctatta agaatttggt ttccggaatg acgccagaaa
     9901 tgaaaacgtt ggttcaagct attctatatt taatggctac attttttgca ttgaaaccag
     9961 gattcactgc tatgaaacat ttcggtgatg caaaatgggg agaaggctta aaatatgttg
    10021 gagccgttgt tgctattttt attatccctg taattacaac tgttatgttg ttaacgatgg
    10081 gtactaaaac aggtaatgac ttaaaccaaa aagctaatat gatctcagct cttattcctg
    10141 tggttggtat ttatctagtt acaaagtttc caaaagaaga acaattaggt taaaaggtaa
    10201 attgagcaaa tttggaggat atgccgattt gttcaattta ctttttgcta aaaaactaca
    10261 ctcgaagcgt agtttttgaa gtgagggaag acaatagatg taagatggac agagaaaaga
    10321 tgttagttca cgcaaacgaa gtattgacga gcggttttaa aggtaccgat ttggcgaaga
    10381 taatgaatat gaacgtaaac cagttctatg attatcgaaa cggcaataaa aagattgaaa
    10441 aagccagact tgaaacgctc atcaaatttg aaaaagcgta tctatacgtg ttagacaaac
    10501 agaaaagaac tattgaccga aaaaaaggag ttttacaata atggcaaaat tcaaagatat
    10561 taccgaatct attaattatg tagcagaaac agttcccgta gttgtactct ctttgaagcc
    10621 acaattactc gaagtgtacc aaaaagaaga aaaagaagcg aaggcaaaaa aagctaaagc
    10681 aaaggtatgg aaagaattcg atgcgttgct gaccaaagat ttaccaaaga agaattacgt
    10741 ggtgattgag gacgtacaaa agctcagcag tgaggaattt ccggatgagg aagatgcgat
    10801 tctagattcc gaaaagtacg ttgttttatt aaaatcaagt ctgaattatg ttgttgattt
    10861 accggaaaaa ttcaaagaaa agctattagc tggtgtccgc tttatggata gtaatggtca
    10921 attattagtt attcctgatg atcctaatat gtttgaaaga gaagttgaag aagctacaga
    10981 cttctacagt gcagtagatc aattagaggt agctactaaa ggcttagaaa gaattgctga
    11041 gaccttcaac tcttctgatg cggttgaatt tgaagctgta gcagaagccg aaacagaagc
    11101 cgtaccagat gaagaagaag ctctttttga ggataatgac gaagcaactg aagcaggaaa
    11161 ccaagaagca agcatagaag aaacacaaac agaaacctac caacaaccaa aaattgatga
    11221 aaaacccgaa tcccagagtg ataaagaaaa ttatgtttat gaagctgaaa aaatcgtatc
    11281 tgaaagtgat gtaccgaaaa atttagatgc tgatttgtta gaaaaagatt ttgaacagat
    11341 catagccaat aaatttcaac ctgtagtttt agatgaggtt agtgatcctg ttgatttgaa
    11401 cgaagagatg cgatccattg cagagttaaa accattgctg tttttagcta aagagagcat
    11461 gaacgctcgt atctctattg ctaataataa aatcaacagt gaattaaata aaacgaaaga
    11521 gcaattgcta ctcaaaggaa agcaaatgtt agcggatgag cttttgcgga tagaggaagc
    11581 aacatcacta agtggtcaaa atcagtttac aaatacgcta tcggtcgcta aagaaagcta
    11641 cgaagcagaa gcatctaaaa ttgatgattt agtgatggaa aaatccagta tcattcgtaa
    11701 agattatgat atggcgaaac aggcttattt ggaagcagaa ctaaagaaac tagagcaacg
    11761 gtacgatgct gaacatctgc cagaagttaa acaacaagaa gatgaattta gaaaagcaac
    11821 tgaagaaagt cttgatcaac aataccaaga agcaattgaa tctattaaaa acgatgcttt
    11881 gaaacaaaat caagaagcaa aagaagttgt ggtggaacgg atcatcaatt cattgaaacc
    11941 ggaaattgaa aaatctttaa cagaagtgca agaaaaaacg ttagagattg tcgaaaaaac
    12001 aaaggcagaa aatgaagctg agttccacga tacaaaagag aaaacaacag atgtggttgt
    12061 caaatatttt gcgaacaaag aagaagttga aaagctagta gctaaagata cgaatgagtt
    12121 agaatccaaa cttgttgcac agcaaaacat tattgaagat tataaaaatc gagtaaaaga
    12181 gttcaaggat ttagcagatg gctataaatt aaatagccaa aaattgactg aacaaagtga
    12241 agctttacga gaagatttat ctcgtgcaag aaacgaccta tcacaaatgg cggaaaaaac
    12301 aaagtcacta gtagttacta cagaaaatca aactgagtct aaacgtgatt ttacaagcaa
    12361 aaagatggcg actatcatcg ctgtatcagc aatggcttgt ggaacgattt tgggctcatc
    12421 ctacttcatt agtcataatc accaagaagc ccaagctcaa acagaaacct caatttcaag
    12481 agtggaaaat tcactaggag caaagacagc ttctacttca acaacagaca acaactatga
    12541 agcaacacca acgacagaat ttaaagtcgg agaagatgtt gtcatcagta ttgatgggaa
    12601 aactactaag gctgaagtac tttccattga cggtgataag gcagttgtga aagctccaga
    12661 tgggaatcaa tacaaaatac aagctcactt aactgaaaag aattaaggag ggctaaaatg
    12721 cgagaagaaa atattgttta tccagtaatt gaaaatcaat caaatacaaa atcttctcaa
    12781 cttcttcaag aagtgcaagt cgtttatccg gttaatgaac taccacaaac gaatgaaaca
    12841 gtgagcaagt caatatcatt aattggcttg cttattgttg caacggcgct aactgttggt
    12901 gtttatcgta agctgaaagt gaaaggaagt atttctgatg gcagataact caaactatgg
    12961 atttaaacat aatttgcatc aaaaaccttc tgaaacaata gtcagagttg attggcttga
    13021 aaaacatgtc aacagcacct attctgttac agcaaaaaga ctaattgttt cagctattgt
    13081 tgttgcagtt gttgttcttg gttcaatcgt ttatttggtt tccgatacga ttaaattgag
    13141 atttattttt attccaacgc tattgatgat aattggtttt cttatactga ttagtcagta
    13201 tatgtttatt gatccatcta gcggatcact gatctcaggc tctattagac tgtttaaatc
    13261 agtagttaac acagcaagag taacgatggg gaaaaagaaa ccatttcgag gaacggagat
    13321 tttgaaagtt agacaagatg gaacgattat gtatcgagat ggtagtgtag cactaatgtt
    13381 taatttggat ggtgctacct cgttaaccgc cttcccagaa gaaatcatag cgcaagaagg
    13441 caaatcaatt caataccaaa atgcaaggga tcgttccttg gctgaaatca aaattacttc
    13501 atcacaacct cagaatacgg aacgtcaaat acggaacatg aaagtacaaa aaagaaatgc
    13561 aaagagcaac aaagctgtgt ttgacatagt agatcaacaa gagaggtttg tatctgaata
    13621 tattgatggg gtcaaaacta cggtgatcca atatcttatt ttgaagtcac aatctcagat
    13681 ggtattggat gaaggcgtag aacgtttaga aaattacacg agtagagggc tttactatag
    13741 cgttactcag ttgtcagcta aacaaaccaa agaaatatta tcagaaattt atgcactgaa
    13801 ataatagagg tgagaaattt aatggaacta atgagtagat cgaagctact taatttcaga
    13861 aaaaagaaac acaaaaaaga gcaaaatgct gatagttcta aagcggtgaa taatacttat
    13921 gtcagtgatt taacatcatt ggttggttat caatttacac catcttacat taggacaggt
    13981 aatcggtggg gaacgattgt taaattagtg aatacgtatg gaatgaacag aaattatgaa
    14041 tttggatgga tggttaaagc tattcctgaa gtgaaggttg aaggagtaaa agcttactta
    14101 atcgaagcgg ataagccagt ttcgcaaaaa gatcagcaag aaatcatgca cgaaaatgtc
    14161 ggtggatcaa cgaacagtta tgaaaataac ttgaacgata aaaattcaga tgcagaaatc
    14221 aataaaactg ttatgcgaat cattgatttg aatacagcat ctctgcttga cagtacggca
    14281 aacaaaatta ttgattggaa gttagaaatc ctcttagtat ccgattctcc taacaagatc
    14341 agcgaacagt tgatcaaact gcaacgcctg tatgatgaaa aaatgtatgg attaaaactt
    14401 atgtcttttg gtggcgatca acgtgatctg tttgataggc ttttaagtga gccagtcggt
    14461 agtgtttacg aatacacatc tatgagttct gattttgcag gaaatgatca cgctatccgt
    14521 aaaggcttag atgatgcaga cggatgggct atcggaacga tgtctacaag ctacgcttca
    14581 ggtgtagcgt ttatggcaat ggatcgttct tttaagggta aagtcttagt agcatcccac
    14641 aaagatgcaa caatcaaagg ctatagcgaa gaaatctcag catcatcact ttgggggcaa
    14701 ttgattgcta ataacgcaat ggcaaatcat aaacggacgt ttcacatcgt attaaataaa
    14761 tttgactact ttggtgatcc gacaggggaa acatttgttg ctaagccatc tttaaatagt
    14821 gtgatagaga agattaatct agctgaagaa ggacttaatt ctttagagct ttttggtgat
    14881 cgaaaggata ttggagattt atatagacgt aatcttgata aactaactca gattttctat
    14941 ctgttagcgg acagagaatt aaatcctgca acaagagtat tgctgaagaa agagttgggg
    15001 aacttttata ttagtcagaa gctttgggat attaactatg aagagcggtc gaaactgtta
    15061 gtaaacagca gtgatacaat gccggttctt ggggatttca tcagctattt aacaaatgct
    15121 gagacaaaag cgaaaaaatc cggtacagaa aaagaaattg atcggattat tgtattaaaa
    15181 gatacattgc gaacagcatt ggatagcttc tctaagatgt tcaatcagag aactacattg
    15241 aaagaaattg gcaagagcga caaattgcag ttttactaca atttgagcga tttaagaaca
    15301 gaaatcaatg tcatggaagc ccaattttta aatacctttg acttcatcac gtcacaagct
    15361 aaaaaaggcg atatcgttat gatccatggg tttgatagat tatcagttga aaccgttgga
    15421 ttaattaaaa agcgactaac aatgcttgaa gaagatggag tccggcttgc gtttctcttt
    15481 gatactatcg gatcaggaga atctaaagac ggtatcgaaa cagctgatat tttcaataca
    15541 gatggaaaaa tttatcaaag ttttgaaagt gattttaact acaccatcat cgggaaaatg
    15601 accagtgaag aattgatgaa gtatgaaaag aaggttgctc ctgcaagaaa aggagaagat
    15661 gatcaaaaac tatcagtgga tttgagacag tatttgacat caggtcgaag caataaattt
    15721 caaatcagaa gaccagcgga tttgactaat aattttgtta ttggagagtt tattatttaa
    15781 gtcttatcct tgtttttgaa tgtttaagga taagaaacaa tatttatata catgactgag
    15841 agaaagaatt atagtggcgg taaaataatg aaatcaaata taaaaataat agcaggtgat
    15901 aaaatgaagg aaaaagaaaa tttagtttgg tattttaaca gaaatccgca tatgctgatt
    15961 acaggaagaa cagctacagg aaaaacttat ctgttgaaaa gaatggctga ctatttatcg
    16021 caagttggta ttgtttctgc ttcttttgac aaaactgaat ttgaagaaat tttatcttcg
    16081 tctcgaaagg aaatggaaga tcggtttgag tatattaaag aaaatcgttt taaaatgttt
    16141 gacgtaagtt actctgattt agacatgaag ccttattttg ttctgataga tgagctagat
    16201 tcaaggttgt tactcttaga aaaagaaaat ccattggctt ataattacct attactaata
    16261 ataaaggata ttgtgttaaa aggacgagta gtaggtgttt tttttattgc cgttcgtcaa
    16321 ggaaagcaac cattgttaga atctatagaa gataatatgt taacacgtat ttttttaggg
    16381 gattccaaag gaaatggaac gatttgtttt gatggaaata caaagaaatt ccaaacagag
    16441 ctagtaacag aagatttctt ttctgtagac tgttagtata gcggaggtta aataatgaaa
    16501 ccaaacataa aaattttaga tcgaatattt ctaggtaaag acacagaagt aatcctaatt
    16561 caacatgaa
//
LOCUS       DAZKCW010000052        16384 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000052 DAZKCW010000000
VERSION     DAZKCW010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.052"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(154..552)
                     /locus_tag="ACG84Z_002046"
     CDS             complement(154..552)
                     /locus_tag="ACG84Z_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFP9162858.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(549..1322)
                     /locus_tag="ACG84Z_002047"
     CDS             complement(549..1322)
                     /locus_tag="ACG84Z_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFP9162859.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1319..2002)
                     /locus_tag="ACG84Z_002048"
     CDS             complement(1319..2002)
                     /locus_tag="ACG84Z_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFP9162860.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2169..3056)
                     /locus_tag="ACG84Z_002049"
     CDS             complement(2169..3056)
                     /locus_tag="ACG84Z_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162861.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3053..3922)
                     /locus_tag="ACG84Z_002050"
     CDS             complement(3053..3922)
                     /locus_tag="ACG84Z_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162862.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4059..5345)
                     /locus_tag="ACG84Z_002051"
     CDS             complement(4059..5345)
                     /locus_tag="ACG84Z_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9162863.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5618..6196
                     /locus_tag="ACG84Z_002052"
     CDS             5618..6196
                     /locus_tag="ACG84Z_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFP9162864.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6196..7125
                     /locus_tag="ACG84Z_002053"
     CDS             6196..7125
                     /locus_tag="ACG84Z_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162865.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7122..8858
                     /locus_tag="ACG84Z_002054"
     CDS             7122..8858
                     /locus_tag="ACG84Z_002054"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFP9162866.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8921..9757)
                     /gene="pheA"
                     /locus_tag="ACG84Z_002055"
     CDS             complement(8921..9757)
                     /gene="pheA"
                     /locus_tag="ACG84Z_002055"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFP9162867.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9754..10263)
                     /locus_tag="ACG84Z_002056"
     CDS             complement(9754..10263)
                     /locus_tag="ACG84Z_002056"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFP9162868.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10256..11551)
                     /gene="aroA"
                     /locus_tag="ACG84Z_002057"
     CDS             complement(10256..11551)
                     /gene="aroA"
                     /locus_tag="ACG84Z_002057"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFP9162869.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11564..12655)
                     /locus_tag="ACG84Z_002058"
     CDS             complement(11564..12655)
                     /locus_tag="ACG84Z_002058"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFP9162870.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12672..13838)
                     /gene="aroC"
                     /locus_tag="ACG84Z_002059"
     CDS             complement(12672..13838)
                     /gene="aroC"
                     /locus_tag="ACG84Z_002059"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFP9162871.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13840..14904)
                     /gene="aroB"
                     /locus_tag="ACG84Z_002060"
     CDS             complement(13840..14904)
                     /gene="aroB"
                     /locus_tag="ACG84Z_002060"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFP9162872.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14937..15959)
                     /gene="aroF"
                     /locus_tag="ACG84Z_002061"
     CDS             complement(14937..15959)
                     /gene="aroF"
                     /locus_tag="ACG84Z_002061"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFP9162873.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
BASE COUNT         4729 a         3622 c         2911 g         5122 t
ORIGIN      
        1 tagcatattt tgaaaagaaa gtctgatgct tagagtagaa tttcataaaa atttactatt
       61 tcataagtat tcacgagaaa aatacaaaca aaaaagcgga aataacgctc atccgccttc
      121 ttgtttgtgt ttatttcctc ttcaaacgct tgtctatgat tcagactttt ctctatcgtt
      181 attttcatct aaaagttctt gcattccgat aatttctcga tattgatgaa tcttagtgat
      241 accaatgact ttgtctacat caatactaaa acaaatacca ttacctggaa tatcgatgtt
      301 gatgccttga ccaatcgcat ccattacttt attcgtcaaa ctatcgggta ctaatgtcaa
      361 cacaatatct ttttctggcg aaatgtccaa acctaaaaat ttccctgaat catgtacacc
      421 agaacctctt ccatgtaaga tcgttccgcc tgctgcacct gcttcttttg aaaagtcgat
      481 aacatcttcg cccattcctc cgtcaacgat cgtcacaatc atgtgaagat tcaatgctac
      541 aagatctttc atttgctttc ccccaatttt tgcaatcttt ctttttcgat tctgtctttt
      601 tcatcttttc gtttataaat atatcctagt actaaagtgg ataatattgg tgtcaatgca
      661 atcattgcaa ccacaccaaa cccgtcaatg atcggatctc ttccttcaat ttgtgcagcg
      721 attgccacgc tcattgataa aataaatgtc gaacacatcg ggcccgttgc tactccaccg
      781 ttatcaaaag ccattgctaa aaagatcttg tccacttttc gtcctaaaat aaatgctagc
      841 ccgtatcctg ggatcaagaa ataataaaga gagaatccga cgagcaaacg ccacatagac
      901 aatcctactg ctgcgccgat cccaattgaa attaccatca gcatgatttt cgatcggatt
      961 ctcccctcgc tcaattcttc aacctgtttg atcattacat gaatcgccgg ctcagcaaac
     1021 cctactaaga accccattaa aaagccaagg ggaaccagta tataattgta aggcaatccc
     1081 gcaatagcac tgcctaaatg ctgtcctacc ggtacataag ccatattgac tccgtgcagg
     1141 aaaaggatca acccaatagt cgttatcaag aaacctttca taatgtcaaa gaaacgcttt
     1201 ttgcgcatac gaaaactaat gatattcatt aaaacaaata ggattacgat aggtgccact
     1261 gccaaaatga cttccatggt aacgatttcg attccatcta tcacttgctg ccagaaactc
     1321 attggaagat cacccccaaa atcatcacgg caagaatcgg ccctaacgaa gcaataccga
     1381 ccattccaaa actgtcattt tcatttttct tttgtttgat catactagtc atccctccgg
     1441 caagggccaa gataaatgga acagttactg gaccagtagt cactcccccc gaatcaaaag
     1501 caatcggcat aaattcggaa ctggtgaaaa atgaggcgat caaaacgcct atgtagccta
     1561 tagccatcaa ttgataatag gatagcttga atacgacccg aagcagcgca aaggctagaa
     1621 atactccagt gccgacgctg acgatcccaa tcagcaacac tctgccaatc tctccgtcag
     1681 atatatcata tacttgttgt cccaaaactt gcacggaagg ttcagcaatc gtgatcacga
     1741 tcccgatagc aaatcccaaa ctgaccaaaa cggtcaaact tttctttttg atcatatatt
     1801 tccctactag atctccgact tccatcatag aataatctgc tccaaacaaa aagagcgtca
     1861 ttccgatcat catgattgcc gcaccaacca gaaatgaagc gaggtcttct ccttctaacg
     1921 gtgcaaaaac aaacgttaaa atgacaatca ggacagtcat cggcaatata gcagcaatca
     1981 cttctttaaa attttttagc atgtatcctc ctcctttact ctttaagttt accttaaaat
     2041 gaaagagttt tcgagcacaa acttaaaacg ttatcattta atttttctca acataaaata
     2101 acacacgtcc caaaagtatc tttttacttg gaaaaatgac tttgaaggaa cgcgcttatt
     2161 gtgttttttt attttacaga gccgatcatt ccttgaacga attgcttttg caaaacaaaa
     2221 aatacgatgg cagttggtaa agtagcgatg actaatccag ccatgatcat tccatagtct
     2281 ggtgtatagg aagcacccat agcagataaa acaagcggaa ccgtccgttt atcaggagat
     2341 tgcaaagcta ctaagggcca taaataattg ttccagctac tcatgaatgt gatgattgca
     2401 gccgcggcat aggtattttt agccgtcggc atatacactc taaaaaaaat acttagttct
     2461 tttagaccgt ctaatcgagc ggcttctact agatcttttg gaaaagattt aacattttgt
     2521 cgaaagaaga agatcaaaaa agcagtgcta acagatggca ggatgacaac caagaaactg
     2581 ttgattccca aaaccgttcc gttcaattgt gaaaacattc gatataaagg gatcatcaat
     2641 gccgcaaaag gaaccatcat cgatagcagt agaatattga aaattaggtc ttttcgttta
     2701 ctttgataaa tctcaaatcc atatcctgcc attgacgaaa tcagcaatgc aaacacagtg
     2761 gtcaccaaag cgatcatcgc tgaattccaa agggaacgag taaaattcag ctcattggaa
     2821 aacaaatttt gaaaattgat gatcaagtta ctgccaatct ttatttttcc cgatgtgata
     2881 tccacgggtg tattcgtcat tcccaaaacc atccagacaa aagggaaaat ggaaataaat
     2941 gataggatgc ttaatgctgt atactttaat actgacccaa ttgtcgaacg aagttctaat
     3001 gcttgttttt tgacgttggg gcgttcgatt gtttcttttt ctaccatatt tttcatcgac
     3061 tttctcctcc tactttcgtt tggattatcg acaatatcac aataaaggaa acaataacaa
     3121 aggaaactgc tgccgcatat ccaaaattag gcgtgaattt ataactcaaa ttatagatgt
     3181 attgagatag ggtggtcgtt gcatttgctg gtcccccgcc agtaatattt tgtacttcat
     3241 caaaaagctg caatgtcccg atcgtcgaag taatggaagt aaacaaaatg attggtttta
     3301 aatttgggat cgtcactttg ataaactgct gccatttaga agcaccgtca atagatgctg
     3361 cttcataaat ctccgaatca atattttgca tgcctgaaag gaaaaaaatc atattgtatc
     3421 cagtccaacg ccaagtgatc gaaagaatga tcagaactct cgcccaaatt ggatgagtca
     3481 accagccaat cggtgtgtca atcataccaa tgcccaacaa caagttgttt acaaggccag
     3541 attgagaaaa tagacttttc atgatcagag aataactgac catcgaagtg atacatggaa
     3601 gaaagatagc ggttcgaaac aaccctttat atttcaactt tttatcattt aaaaggttgg
     3661 aaataaaaag tgctagaaac aacatgatcg gtacttgtac aagtaaatac aggaatgtat
     3721 taaaaaaagc ttttttaaaa gttgcatctg tcaacatccg ctgataatta cctaacccgt
     3781 taaatgtcat attgacaggg ggaccacttt gaaaagacgt gatcaaagcc aaaaccatcg
     3841 gaataaaaac catgattgat atcaaaatga ctggcaagat taaaaaagca tgcccgtttt
     3901 tgaataaatc tttctgcttc attcttttcc ctccaattct atcattgatt atctacatga
     3961 aaagacaaga aagacaatat ctgtaaggca gacgtgatct tttttgtctt ttcgtttgtc
     4021 tgatgaaaaa gcgaagaaat tcactttttt accaccgatc aattagccaa ttgtgcttct
     4081 acttgttttt gtgtatctgc tagtaccttg tctgtctctt ctccattgat gattcgatga
     4141 agagcttcag ctacgactgc ttcaattgca taggtctcat gtccgtaatt cacttctggt
     4201 atttcagatg tccatgttga aaaatcgtca aagatctttt gaccactgta aaattcagaa
     4261 gcttcttgat aagcttcttg ttcattcgcg ctaagcatcg tagatactag tccgatttct
     4321 ttcgcaagag tgcccatcag ttcttcattc gaagcaaacg ttgcttctag gaaatctttc
     4381 gctgaatctt ctccagctac tcctttgatc acataccagc cagcgccgcc aaggttagaa
     4441 gcttgcgctt tttgcagatt ttctggaagt gcaggtattg gtgcaatctt ccattttcca
     4501 gattggtttt ctgctccttg gatcgttgaa gaataccaag cgccagttgg gctagaagct
     4561 actgctcctg attgtatcgc agttactcca gcattccagt cagaggtttg ttcgactaga
     4621 tcttctttca aaagagtggc aaacaattca agaccatact ttaaagatgc attgtcttgg
     4681 atcgtgactg tctccccatc ttcagatgta taccattctc ctgcctgttg cataatcatc
     4741 cttactcgac caaggtcaga aggattgact tcagcgattt tctttcccgt cttttctttg
     4801 acatctcgcg ctacttgaat atactcgtcc cacttcagat tctccatatc ctcttctgta
     4861 taacctgctt ctgccatcag atccgtacga tagaagtttg ctgttacgcc cgaatcgaaa
     4921 ggaacaccgt atattttatc tcctactttg tttaccgcaa atttatacgg tgcaaaatga
     4981 tcttccttta caatagcaga caaattagcg aatgcatctg gataagaagt caaatagcct
     5041 tgtatcctat aatcttcaat caagacgata ttgggcaatc cttctgtatt cccgctcgct
     5101 aaagcggtgt tcagtttctg aacgatatca tcctgagaca tcgtaacaac ttctatctct
     5161 gtttcttcgt tctcataaac tttttttgct tcattcactg ctttgatatt gaatgtctca
     5221 tcccacgccc agacagtgac tttttcttct ttgtctgctg tactactagc acttccgcat
     5281 cctgttaaga aacctgatgc tgccgctaaa caaacgactc cagcaattaa ctttctgatg
     5341 ttcattttta tccgctcctt ttccatccat tagttgttta cgtttgctac attcatcata
     5401 ccaaaatttg aaaacggttt ctttattatt cagatacttc aaaaatttct cctaaaataa
     5461 taaaaaaata caaatcaact atgacaaaag gaataatctt agcatctaga ccaaagatcg
     5521 aaatggtgag gtttctttaa aataaaaata tccttgcatt ttctcctaga aataagtatt
     5581 tttaaattac aagactattc ttaaggcggg taaaaaaatg ccaatacgcg taattcttat
     5641 cgatgatgaa cagacgattt tagatggaat gaaacagttg atcaattggt ctgagcacgg
     5701 gtttcaatta atagggactt tttccagtcc gctgaaagcg cttgattttt ctttggtaca
     5761 tgcaatcgat atcgtggtca cagatgtaat gatgcctgaa ttaaatggaa tcgaattatc
     5821 gcggctatta aaacagcaac aacctgaaac acagatcctt atcctctcta gctatgatga
     5881 atttgatatg gttaaagatt cttttaaaga aggcgtcgct gattatcttt taaagcctcg
     5941 attgagtcct gatttttttc taaattcctt aactgccgtt tcacaaaaaa tcaaaaaaaa
     6001 gcccaacaaa agcccaatca ccaatcgtta tgagcagatc tgcgagaatc tttcacagca
     6061 gattgctgga caaactcgtc cattgcttga ccctcttctt tttgaacaca ccttgttttt
     6121 ctgttatata ccgaaaaacg gccattcagt tcaaaacaag gctctaaaca aaaacagtcg
     6181 atcacccatt cattgatgga tagcgacgat tcgtttacta tttatcctgt ttctaccttt
     6241 tcggaagaat ccggctatgt aatcaatact gattccaaag atacacttag gaagtttgtt
     6301 caaaagtttc gtcaagaagt ttttccaggt gatttttttg ttgtttctga ttcttttgca
     6361 atccaagata tcaatgaaat attccaagag atcagaaatt gcaccaaagg acaacgtttc
     6421 tatcataagg gaaagaacct tgcttatcag catgaacttc ttccgttatt aaccaaccac
     6481 gagcagcaag caagtagtta tttaacaaaa atcgttcata aagactacgc tttagctgtc
     6541 aaagaacttg agaatttctt cacgacgata ttggaacagc ctattgatcc agcttatttg
     6601 aaacatgagg caatcaatcg tttctatgca ttactcaacg ctttggctga cgagcatgtt
     6661 gggaatgaag aactttcttt gctcaagatc gcccttcctt ctttattagc cgatgctgag
     6721 tatttcgaag atttttctat tcttgtcaaa gaaacacttg agaaactcac ccacttttct
     6781 gcaaatgcaa aaaaagacaa tttcgatatc ttgactttga tctacgagtt cgtccaggaa
     6841 aattatgaga aagaaatcaa tttacaactt ttatccgaaa aatatcattt ttcatatagc
     6901 tatctctcag ccatctttac tgaaaaattt ggtatcaact tttcaaaata tctaaaaaaa
     6961 gtccgtatca gtaaagccaa gctctttttg acggaaacac ggcttacttt gacggaaatc
     7021 tgtgagaaag tcggctatac cgaactgggt tatttctcca gagtttttaa agaagagaca
     7081 ggaatgacac cttctcaata ccgtaaagga acttttgtaa aatgagaaaa aaaatcaaag
     7141 agcatgaact ctttgccaaa cttctgttca ttttgttcat cggtcttttt ctgcaagcca
     7201 tcgtcatttc tttgtttatt tatcatcgat caagggatgc ctatatccag ctgttcaatc
     7261 aatcgaatga tgtggtacta aaaaagattc aatctgaatt tgaaagtttg aatgatacaa
     7321 tcgagaatac attagccgct tttgattcta atccagctgt caaaagctat ttttccaatg
     7381 atccagccca acatatggaa cagcttcagc aactaagaac aatccaaaaa atgaatgact
     7441 ctctttcaaa aatccatcca atgatcgatt acgatgtatt gatctttgga gaaaatggaa
     7501 gaacttttgt cggaaacgac atgctcactg ccgtatctgc cgattctttt tttcaatctg
     7561 cgattgctca gagagtgaat gaacgtgctg ctgatacaca aatgcttttt gcacaccacg
     7621 gattgactct tcgcgataag aaagcaccca gcgtcttctt tgtcaaaaaa ctgaaaaata
     7681 cattgaatca cgtttacgga tatgctgttt tatcgatctc atccaagcaa ctagcgaatc
     7741 tttttcaatc tgtagtaaat cctgagatat cgaagatctc cttcatgaac gaagaacaga
     7801 cgatcatcgc atcaaatgaa gaaaatacaa ttgggagccg atcaatgatt ttcaaaaaac
     7861 taacagtagg tgaaacaacg atttcaaatg gacagcagtt gacccgtctt cctctgtacc
     7921 gccaggattg tacattactc agtcaagtcg atcttcattc tttatctaac caaatgggcg
     7981 tgatttttcc gattattttg tataatatcg tgacacttgc ttttgctggc tcattggtat
     8041 ttatgtattt ggatcgacac acaaaatcga tctaccgctt gattgattcg ctaaaacggc
     8101 tagaggaaga tggcttaaaa gctactgttc ctgtacaagg aagccatgaa gtccaattgc
     8161 tagggaatac gatcaatcaa ttgctaagta atgctcagca tcattatgaa cagacgatcc
     8221 aagacgaaaa gaagaaacgt tcgcttgaaa tccaaactat gcaagcacag atacagcccc
     8281 attttattta taatacgctg actagcttga aatttttgat ttggcagaaa aaaacagatg
     8341 aagcagttca aggaatcgac agtttcatta ctttactaag aagtacgatt gggaaaaaag
     8401 aagaagtgat tccagtcaag gaagaaatca aaagcgtaca aagttacatc gatcttttga
     8461 gtatgcgata tggcgaaaga atctcggcta aaataatgat tcctgatgaa ctgcagtcat
     8521 tatctatgcc gaatatgatc cttcaaccaa ttatcgaaaa cgcctatctt catgcttttc
     8581 acaataaaac gcaaggattc atcacggtgt acggcaaaac aaaaaatcag cttcttttat
     8641 tcgaagtgat tgataacggc gatggcttcg atactgaaaa taccaaacaa aaaaatgatc
     8701 atttttcagg aatcggcatc agccatgtag atgagcggat acgcctaatg tatggcgatg
     8761 catatggctt aacgatccaa tcagtgattg ggacaggaac gactgtaacg atttgtctac
     8821 cgcttcttcc taaaaatcaa tcagaatatc aaaaataaag aatagccaag cgctgatttt
     8881 tttattttaa gttaaataaa tcaatcagta ttcttgactt tcatctacgc gtctcttcta
     8941 ctgtcagcac tggataacag cccaatattt gactttctcc tccgagcatc ttgatttctt
     9001 ggagcgcatt ctctactaat gtcattggac ggtccaacaa caaatcgatc acgaaaaaat
     9061 attctcccaa gctagttttc aatggtcggg attcaatctt acttaagttg atttcccgcc
     9121 agccaaaagc tgccagcatt ttatgaagca tccctggccg attagcaggt agtgtcaaga
     9181 tgacactcat ttttactgga gctgactgct ggctggtcat ctttcggtca ccgacgatcc
     9241 aaaaacgtgt ctggttcaac tcattatctt ggatattctc agctaagatc tccaatccaa
     9301 catgctgtgc tgtttctaat gaagcaatcg ctgctgcgtc ttctttcgga tgttctgcta
     9361 catacattgc tgcagcagtt gttgattctg ttgctactaa aggaacatta ggataatgcg
     9421 tttctaaaaa ctgttgtgat tgtgctagtg cttgtggatg tgaaaggatt tttgtaatct
     9481 ttgttgctgg attgcctaaa agctgctgct tgataggaag aacgatttca cttttaactt
     9541 cgacttctgg atgtttggaa agaagatcga ttgtgtgatg aacagctcct tccaatgaat
     9601 tctctacagg aacgacagcc agatcgactt gtttgcgaaa caaagcgcgc aaacaaacag
     9661 ggatggaagc atacgcagtc aattgttctg taggaaatag ctgacaagcc gcctgataag
     9721 tgaatgaact ttctggccct agatagctga cgttcatatg cttttgatcc tttctataat
     9781 ggtatcgatg atcttttctg gtgtttgatt ggtcgtgttg attcgatgtg tcgcactttc
     9841 ttcataccaa gaaagtcgtt gtgccaataa tgcttttatt tcttctcttg tttttccaag
     9901 agctaaaggt cgaatagacg tttcatcttg ttggatacga tcaactagac agtccgcttc
     9961 tgcctctaag taaagaacaa tcggctgtgt ttttaaaaaa cgccgatttt ctgcactttg
    10021 gacaatccct ccaccagtcg cgataatttt gtcttcattt gacagctttc ttaaaatatc
    10081 tgactccact tttcgaaagc ttttttcacc gtaatagtga aaatattcgg caatcgacaa
    10141 ttggatatgt tcctcaatct ttgtatctaa atctacatac tctttttgta aacattgagc
    10201 taacccttta ccgattgttg tttttccagc gcccatgaaa ccaatcagca aaatgctagc
    10261 catgagcttc tcctcctgac acaagttctg ctaaatcgtc aaaaaatgcc ggataagaga
    10321 ttgaaacagc ttcagctcct tctagttcgc aaggtccatc agctatcaaa gcagctactt
    10381 gcagcatcat accgattcga tgatcgcctc tgctggacac ttttgcgcca tgcagaggtg
    10441 tcggcccatg gatgatcaga ccgtctgctg tcgcttttat ctttgctccc attttctgta
    10501 attcttctgc caccgcatca attctgttgg tttcttttac ttttaattct tctgcgtctt
    10561 tgatgatcgt gattccttct gcttgagtag ccactaaagc tagaatgggc aattcatcaa
    10621 tcagacgcgg aatgatttct ccaccaatcg ttgctttctt caaatgactc gtcttgacac
    10681 ttaaatcagc cgattggttc tgttcattgt gattcgtctg ggtaatcgct gcgcccatct
    10741 cctccaacac atctaagata ccagttcttg ttggattgac cccgacattt tttaacaaca
    10801 gttggctttc cggaacaaga agtcctgctg ctagaaagaa agcagctgat gaaatatcac
    10861 ctggaacagt tatctgttga ccagttaatt tttgcggtcc ggtcactatg atcgttttat
    10921 cttccactgt gatccttccg ccaaattgac gaatcatttc ttccgtatgg ttacgggaac
    10981 gttctttttc aacgattacg gatgtgcctt ctgcttgtaa tgccgcaaac agcaaagcag
    11041 atttgacttg cgcactggct acaggcatat tgtatcggat aggtgataaa gagcgggttc
    11101 ctgtcacagt gattggtaga tactggtcat tttcttctcc ttgcaagtca gcgcccatct
    11161 cgcgtaaagg ttccatcact cgccccattg gacgtttaga caacgaagca tccccgaaca
    11221 gagtagtcgt aaaaggctgt ccagccaaaa tacccatcaa taaacgtatg gtcgtaccgg
    11281 agtttcccat gtcaattgat tcggttggtt ggacaaatga gtggctaccg cgaccatgaa
    11341 tcttgatcac ctcttcctct tcttcgatct cgacacctaa ttgttggaag gcatgtaaag
    11401 tactcagaca atcttctgcg cgcaaaaaat tttgtatagt cgtcgttcct tcagcaattg
    11461 ctccaaacat gatgctgcga tgggaaattg atttatctgc tggtatccta acagtccctc
    11521 ttaatccatg tatttgttgt aataattgca tttatccagc ctcctatttg atccagcaat
    11581 gataactggt attagacata atgattcttt ttgcttgtaa caaatcctgt tggtttttaa
    11641 aactgatttg cagtattcct aaaatatctt ccctggtctc ttggatcttc aaattaatca
    11701 aagaaactcc cgcttttccg atcagtccag ttacttctgc aataacgcca ggttcatctg
    11761 gcacatcgat aaataaatca aaaaaggcag gaatcgcgcc ttgcttatgg acaggcaact
    11821 ggtctcgact ttcttttgcc cgattgaaaa aagaaaagat ttccgattgg ttctcagtca
    11881 tgatccattc tgctatttgt gtcatttctt gttgccaatc tgccaatcgt tccaataata
    11941 tctgcttatt gctcaacaaa atatctgtcc acatgacagg atctgaggaa gcgatcctag
    12001 tgatatctcg aaagcctcct gctgccagtt gtttggctcg cggatactct tgattgaatt
    12061 gttctgcctg attgactaag ccagctgcca gaatatgtgg aaaatgactt agcattcctg
    12121 ttatacggtc atgttctctt gctgtaagag ttacatattt tgctttggtt ccgcaaaata
    12181 gttcttgcag tttttcaaca tcttttttcg tcttttccaa aggtgtaaag atgtaatagg
    12241 cattttcaaa tagtttagca tctgctgcct gtatacctga tttatgagaa ccagccattg
    12301 gatgtccacc gacaaaccga agatttttct gctcagcgga tgtcacgact tgctgcttcg
    12361 tactgctgac atccgtaatg atgacgtgat cagacaagtt gattctttca aggacatcaa
    12421 gataagctaa ggttgtacgg acgggaacgg ctaataagat aacgtctgct tgttctgcac
    12481 ctgtttcaaa atcacttgca acgtaatcaa cgatctgctg ttctactgct tgctcacggg
    12541 tttttgactg actatcccaa ccaactacta tcagttctgg attggtctga cgaatacaaa
    12601 gtgccataga agcaccaatc agtccaagcc ccacgataaa aacatgttgt gccatcttat
    12661 ttgccccctt tttagtaatg tttcaagtag tcacggtact ccttcactgc agctttcaac
    12721 tcaacaagcg aatcacttgg gaattttgac aatagctctg tcgctaccac agtggctaca
    12781 acattttccg caacgacgct agctgcagga actgctgtac tatccgaacg ttctacactt
    12841 gctttgtaag gttcttttgt atcgatatca acactttgaa gtggcttgta caatgtagga
    12901 atgggtttca tgaccccgcg aatgacaagt ggttcgccat tggtcattcc gccttcgaag
    12961 ccgcctagat tattggtacg tcggaaatag cctctttctt cttcccatag gatctcatcc
    13021 atcacttctg agcctggtaa tgaaccagaa gtgaatccga ccccaaattc tacgccttta
    13081 aaggcattga tactaaccac agcttgtgcg attttggcat ctagcttcgt gtcccattgt
    13141 acgtagcttc ctaatccagc tggaacgcct ccaacgagca cttctacaat tcctccgatc
    13201 gtatctccat ttttctttgt ctgatcgatc aaatctttta ttctttgctc aactgctgga
    13261 tcaacaactc gtacttctga cgcttcagaa atttctttga tttcttgaat cgagatattt
    13321 ccaggtattt ctgcttggat tccaccaaga caaatcacgt gtcctgctac gatgatgtca
    13381 agttcttcca gaattttctt ggcaattgcg ccgattgcta cacgcatggt cgtctctctt
    13441 gcagaggacc gttcaagcac attccgaaga tctcgatgat ggtatttcat accgcctacc
    13501 aaatccgcgt gtcctggacg cggacgtgca actcgccgca gtgattggtc tttttcaggc
    13561 acttctgcta cagacatgac agttgtccaa tttttccaat ctttattttc taccactaaa
    13621 gtgacaggtg aaccaattgt tttgccgtga cggatgccag acgtgatccg aacacgatct
    13681 ttttcgatct tcatccttcc tcctctgccg taaccagctt gtctgcgagc gagttcgtga
    13741 ttgatttctt cttctgacag aggtaatcct gctggtagtc cttcaataat ggctgttaat
    13801 tctggtccat gggattctcc cgcagtcata taacgcatct tacagtcctc ctaagtaatc
    13861 tttgaatgtc tctgtgggaa caggaacgat ttttgcttgc ccaatctttt ctagcaagat
    13921 gatattcaat tggcttcctc ttgctttctt atcatgggtt atcgcgtgga ataattcatc
    13981 tggatgactt agatcgtacg taatcggcag atggaatttt tgaagtatcc tttctaaagc
    14041 agctgtcgat ccagttggag acaagccgat tttttctgca tgagaagtga tggctaccat
    14101 tccaatagct actccttctc catgactgac taccccatat cctgctgtat tttcaattgc
    14161 atggccaatt gtatgaccaa aatttaaaat aagtcgattt ccttggtcaa agacatcttc
    14221 ttccactact tttcgtttga tttccaacgt agcagtaatg attggaacag catgttccag
    14281 aagatctttt tcgtctttca gctcgttcag ctgtttccaa agcgttgcat ctgctatagc
    14341 tgctgatttg atgatttcag cgattccttc tcgtaaacga cgtaccggca aagtttttag
    14401 aacctcagga tcaatcaata caccagctgg ctggctaaat gttccgacaa ggtttttcgc
    14461 tttgtttgta ttgactgctg tcttcccgcc aatactagaa tctacttgtg caagtagcgt
    14521 agtcggaatt tgaacgaaat ggatcccacg catgaacgtc gaggccacga atgctgctag
    14581 atcacccacc attcctccac caagtgcaag tatcccatcg ctgcgggtaa aatcattatc
    14641 tgctaaaaaa tcgtataact cagctgcttg ttctaaagat ttactggtct cacccgccgg
    14701 tacgattgaa aggactggtt caaaattagc ttgtctcaat tggaacatga ttttttctgc
    14761 atatagtgga gcaacgtttg tatcagtgat cacagctact ttttgaggtc tccaaatcgt
    14821 ttgaagccat gatccagcct gttctagtgc gcctttttca atatgaatat cgtatttttg
    14881 gttatcaaca tgtacagtaa gcattcgttt cacttctttc ttttaaaaag ctggaattaa
    14941 tcgagtgtct gaatcttttc cattgcttct ttcatgatcg caacttcttt catcatgcgt
    15001 gagtaagtct tttcattcaa cgattgggga ccgtctgacc aagcatttgc aggatcagga
    15061 tggatctcta cgatcatgcc atctgctccg cttgccacac ccgcacgagc cattggtggt
    15121 acaagttccc aaattcctgt accatgactt ggatcaacaa tcacagggaa atgagttaat
    15181 tttttcatca atgggacagc acttaaatca aacgtattac gtgtcgctgt ttcgtaagtc
    15241 cgaatcccac gttcgataaa aatgacagga gatttgtctt cgactgcaat gtattctgca
    15301 gcattaagcc attcattgat cgtaccggaa attccacgtt tcaatccaac aggtttacct
    15361 gttttaccga cagcagatag cagtttaaaa ttttgcatat tacgtgcgcc aatctgtagg
    15421 atatcgctgt actcagccac catatcgata tgcccttcat ccatcacttc agtaatcact
    15481 ttcattccaa attcatcagc cgcttgacgg atgtatttca atccttcttc ttctaaacct
    15541 tggaaagcat atggagaagt acgtggtttg aaggcaccac ctcgcagaat ttttgcgccc
    15601 ccggctttgg ccattcgcgc acattctctg atttggtcta atccttcgat agaacaagga
    15661 ccagccatcg tcacgaaact gccgtcacca atttttactc cgtctacatc cacgactgta
    15721 ttgccaggat ggaattctcg agaagtcaat ttgtatgtgt ttaaaatacg cacagcattt
    15781 tctactcctt catagcgtgt aaatgctcct tcttgtaaac ttcgcgtatc accttttagt
    15841 ccaatcacta ctcgttctgt tccttgatcg attgagactt tgaatccttc tttttcgata
    15901 tgatcgacga ctttttttat ttgttcttcc gttgcttctt ttttcataat tactatcatt
    15961 gtttttcccg ctttcttttg tttacttatc tatcttggct gattttctct actttttcaa
    16021 ggtggtttta cattaattcc tactaaatga ccgtgtcctg ttgttctcat tttcgctcct
    16081 tctttcctac ttatgaccca gataatcaac aaaaaaagat gtccctgtag gaaattgcct
    16141 ctacagtgaa catcttcaac gagccttaaa aagcgctgca aaaatataaa atagccacta
    16201 tagatgaatt tctctacgtg gctgtaagtc gtgtttaaaa atctttagcc atcatagata
    16261 caaacctggt ttgtttgtac ccacgaagtc atgaatacaa acctatctaa aatagctaaa
    16321 gtaatacgta ttcagttttg taagttttct agatttcata aaaaatcgct ccaaactgat
    16381 gtaa
//
LOCUS       DAZKCW010000053        16220 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000053 DAZKCW010000000
VERSION     DAZKCW010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.053"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..477
                     /gene="scm"
                     /locus_tag="ACG84Z_002062"
     CDS             <1..477
                     /gene="scm"
                     /locus_tag="ACG84Z_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFP9162874.1"
                     /translation="STDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSST
                     TTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNR
                     TNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(632..1618)
                     /locus_tag="ACG84Z_002063"
     CDS             complement(632..1618)
                     /locus_tag="ACG84Z_002063"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFP9162875.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1641..2207)
                     /locus_tag="ACG84Z_002064"
     CDS             complement(1641..2207)
                     /locus_tag="ACG84Z_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFP9162876.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2221..2637)
                     /locus_tag="ACG84Z_002065"
     CDS             complement(2221..2637)
                     /locus_tag="ACG84Z_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFP9162877.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3094..5028)
                     /locus_tag="ACG84Z_002066"
     CDS             complement(3094..5028)
                     /locus_tag="ACG84Z_002066"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFP9162878.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5330..6265
                     /gene="pplA"
                     /locus_tag="ACG84Z_002067"
     CDS             5330..6265
                     /gene="pplA"
                     /locus_tag="ACG84Z_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFP9162879.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6355..7458
                     /locus_tag="ACG84Z_002068"
     CDS             6355..7458
                     /locus_tag="ACG84Z_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFP9162880.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7471..8424
                     /gene="menA"
                     /locus_tag="ACG84Z_002069"
     CDS             7471..8424
                     /gene="menA"
                     /locus_tag="ACG84Z_002069"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFP9162881.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9238..10584)
                     /gene="gor"
                     /locus_tag="ACG84Z_002070"
     CDS             complement(9238..10584)
                     /gene="gor"
                     /locus_tag="ACG84Z_002070"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFP9162882.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWKASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10718..11971)
                     /locus_tag="ACG84Z_002071"
     CDS             complement(10718..11971)
                     /locus_tag="ACG84Z_002071"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFP9162883.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(11977..12900)
                     /locus_tag="ACG84Z_002072"
     CDS             complement(11977..12900)
                     /locus_tag="ACG84Z_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFP9162884.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13121..15613)
                     /locus_tag="ACG84Z_002073"
     CDS             complement(13121..15613)
                     /locus_tag="ACG84Z_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFP9162885.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15620..16087)
                     /locus_tag="ACG84Z_002074"
     CDS             complement(15620..16087)
                     /locus_tag="ACG84Z_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFP9162886.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         4767 a         3393 c         2885 g         5175 t
ORIGIN      
        1 agcacggaca cgtcagcttc aagcgacagt acggatacat ctaccacaac aagtgatagc
       61 acggacacgt cagcttcaag tgacagtaca gatactacct ctaccacaag tgatagctca
      121 gattcatcta ccactacaag tgatagcacg gacacgtcag cttcaagtga cagtacagat
      181 acatcctcta ccacaagtga tagctcagat tcatcaactt caagcgatag tacagacacg
      241 tcgtctacca caagcgatac acgtcatgca agtgtctcct tctcaaaaac aagttcggat
      301 aacaggacga actttaactt aactaataaa acaagcaatg acaatggaaa caaatcaaaa
      361 agagcacttc ctaaaactgg aagtcaatcg aataattgga taacactcgc aggcgttata
      421 ttacttgtaa tcggtttaag aatcactttt atgagttata agaaatcgaa aaggtaaaaa
      481 aatattcaag ataaaaaaga gcaacgtcgc taacggacgt tgctctttat ttttgctttt
      541 tatcataaat acaagaacta caattcaatt tgtcaaaaaa cacgtagatt tccttctgag
      601 aaatttattt acgtatcgaa cctttcccta ttcagtcttt gcgatccaaa atcagttggg
      661 taagggaaaa gagattctct tttgttcgaa gagaggtggc aggtaatttc tttatttcct
      721 tcaaagcctt ttctgtgtaa gaggccgcta acttcctagc ttcttccacg cctcctgtat
      781 gttcaacgat tttgcgtacg gcgtcgacat cttcttctgt cattgccgct ttcttctcta
      841 aataaggtag tagctttggt ttgttttttt gcaaagagta gatcaacggt aaagaataga
      901 ccccttgacg catgtcttct agtacaggtt tgccgatttc ctggctctct tttgtataat
      961 ctaaaatatc atcgataatc tgaaaggcca tcccgataga aagtccgata tctcctgctt
     1021 tttttgcgaa gcgctcgctt gttccacttt caaaagcgcc aacagaacaa cttaattgga
     1081 acagttcagc tgtcttacct gaaatatttt ccaaatattc ttttacagaa agttcataat
     1141 tatagcgatc atccatctga cctaattcgc cattcaatac tttttccata ctgcgagaat
     1201 tcaattggag acttttcaag gaagtggagt aatcagacaa tagtttaaaa cagcagacaa
     1261 ataaatagtc tcctgcatag acagaaacga cattaccaaa ctgactacgg atattaggct
     1321 gaccacgtcg cagatccgct tcatcaacga tatcatcatg gatcagtgtg gccgtatgga
     1381 gcatttcgat agaagctgcc aaagcgatgg ctttgtctcg atcttgctct ggtccaaatt
     1441 gtgagaacaa tagctgatag gcaggacgca acagctttcc gccggcatgg atcgtttctt
     1501 tgattgcttg ttcgacaggt ttgtttttca ggcggacagt ttcttccatc cgttttagtg
     1561 tttctgtcaa ttctttactt aaagcaggat agttttccca cattggatgt agcttcataa
     1621 aaaaactcct tgtgtgacga ttattttttg gtaaacattg ggctccattt ttgtttggtt
     1681 ccctgctcat aatctttttg gaatcgttga agtgtctgca catgtcgtaa aagataattc
     1741 gctgcgatcc cgattgcaat ccctgataaa atccctaaaa ctgaaaggac tggcaagtac
     1801 aacatgactg tccatgattg tgcaatgaaa gaagccatca aaagctgtcc gacattatgc
     1861 atgaaaccgc cggccgcact aattccgatg atactgacac gttttggtcc taattgcttg
     1921 accaataaca ttccaaaata actaagcaaa gcaccactca tactataaag gaatgtggaa
     1981 atcgttccgc ctagcaaagt agtcaggaat agtcgtagcc aaagtagtaa gaagctgtct
     2041 cgttttttca tggtaaaaat ggcaacgatc gtgattagat tggctaagcc tagttttgca
     2101 ccaggcgcaa aagaaaaagg ataagggatc atattttcca ataaaccaat gatcactcct
     2161 tgtgcaacaa gtagcgaaat ataaatcatt ttttgtaatt tactcatggt gtgtgaaggt
     2221 ctaataaatc agactgtctt cgtcacctcc atctgttgaa cggacttcga tcactaattt
     2281 atgtggcaaa cagacgatgg tttcgccatt tttcgttgcc cagcctcgac gtacgcagat
     2341 ctggtcatcg caatctgctt cttttatccg tactcgatcg ccatctatct cgatcaagtt
     2401 ataatctccg tgttcatctt tgtaagtata tgtgttgctc tcttctccag ccatcaaagg
     2461 gaatgttttg atttctgtgc catccacacg cagtaccgct tctttttctg ctgttgcggt
     2521 gttttgctga agaccaaaaa tcatgactgg taaaaaagaa agaacagtca aaagcaaaat
     2581 aataaaaaca tcccaaggtt tgagcagact tttttcagca aattctttaa ggctcatttt
     2641 tgttctcctt tttccagatt aactcaccca attttagcat aaaaacaaga ggttgtgaca
     2701 cctgtgtctt gctttgagta ataagaacga agaatagaaa acagctttcc atgttttcta
     2761 attctttggg cttattaccg agaagcagca ggtggaacac cgtttataac aagaggttgt
     2821 gacagaagtg ggcaacttca agaaataaga aggaatttac gaaaattact tttcaagttt
     2881 ttgtgaaatt tcggcttatt tttcgaagaa gctacttctg gaacaccgtt tataacaaga
     2941 ggttgtaaca gaggttgtga cacctgtgtc ttgctcatgg aggcttatct cgggcatctt
     3001 attcctttaa ttttacataa aaaggaggct gtgacggttt gtctcagccc ctttctattg
     3061 aaatcttgca ttcaaataac gttctttatc tatttatttc ttgccgtact gggaacttgg
     3121 tctaccgtac caccaattac ctagtgtacg ttgtagccat ggaattaccc agcgatccaa
     3181 cccaatcgca cgtccggaac cgttcatcaa tgcgaaagca acaaaaatga accaaatgtt
     3241 tacccagtaa aacatgcctg ataagcagaa cgtgatcacc aatacaatcg ttgtcgcact
     3301 gcatagccat gtgaataatc cagcaatcaa tgctaatgcc aaggcaattt caaagaatac
     3361 catgaatttt tggaagaaca ttgctacatc attgtttggc atgatcactt gcatgatctt
     3421 tgtgaaccag tctggtgact tctcaatcac agccattggt tcttcaccgt atgcataact
     3481 caaaccaaaa tgtgcagctt gagtcgctgc ttctccggca cttgcccctg ctccgctggc
     3541 agctgtggtt gcatcaccag cagcagaagc accactggca acatctgtta cattgtattc
     3601 ccatgtccaa gggaacacac tgtttccagt gaaccatgat ccttcaccaa accaagtact
     3661 tggtttgaac acttcaccat tcccaatgat ttttttggaa gcttcaacga accaaactaa
     3721 accatagaaa atacgaagtg gcacactcca taagacattg ccgtaacgag aagaatgtcc
     3781 tcgagtcacg ttgcgatcat ctttgatatg gaaaaactca tgcattaaat attggaacat
     3841 ataataacca gaacgaatat caaagaagta tttcaaattc acgatatgtt tcattacgat
     3901 agctaaaaat ccgcttaaat ggatcttatc aaataggtta gctacccccc atttggcacc
     3961 aatagaaacc ataaatcctt gatagtttcc tttaaattta tgcttttctc cgcctttgat
     4021 cgaagccacg atattcgctg cggctgtgtg tcctgtttgt tcagcagctt gaacgatctg
     4081 cggtgtcggt gttcctggga attcttcata aaagactaaa tcaccaatga tatagatgtt
     4141 tttatcttcg tagccttttg cctgcatata ttcattggcg atcaaccgct gtccgcgtgc
     4201 tgattctaat ccaaagtcag cagcgtcaga agttcctttg acaccagctg tccaaatcag
     4261 tgtgtgagtc ggaatgttgc gtccgtcttt caatttgata tgatcagcag ccacttctac
     4321 gattggtgca ttcaataata attccacgtt gtgcttacgc aaatagcgtt cagcttttgc
     4381 agcatcattt cgatccaaca tattcaagat cgtcggcatt gcctctacga ccatcagtgt
     4441 gatttcgttt ggatctaatt tataatcttt ggctaggcga tttttccagt cgatcagttc
     4501 cccaatcatt tcaataccgg taaatccaga accacagaca acgaaagtca gcatggcttt
     4561 acgcagttca tcatctggtt ccaatgcagc ttttgctact gtcttctcaa tatgttcccg
     4621 aatccttaca gaatcttcaa atgaccaaag ggtgaatccg tgtgctttga caccaggtgt
     4681 accaaagtca ttcggctctc cgcccattcc aaggatcagc tgatcaaaag gataggaacc
     4741 taatttggtc ttgacgattt ttcgttcttt atcgataccg attacagtgt ctgtgacaag
     4801 ttgtacattc ttttgacgag caaacaaatg ctgcagatcg tattggattg cttctggttc
     4861 tacacgtccg ccagctactt catgcaactc ggtcatcata gtatggtacg aatgacgatc
     4921 gatcagagta attgctacat cttctttttt cagtttcttt gccaagtatt ttgtagctga
     4981 aacaccggca tatcctgctc ctacaacgac aatattttgc tttgccattg atcatccgct
     5041 ccttatagac tatctatata atgaatatat gataattctt ttagtttgat acttattaca
     5101 caatctccat atattatata gatgttctgt tcttttgtct aactcctttt ggattttttt
     5161 caaattttaa aataaagcgt tttttcacga aatttgctga aagaaaacgt ttgaaatatt
     5221 acatgggtta tttatcaaaa atagttgact tataggctaa aaagattaga atgtataatg
     5281 aatcacaaag aaaaattgtg gactagaaat ggaatggtgg ggtattaaaa tgaagaaaaa
     5341 acgttttgta actggatttg ccgtattagc attttcagct ctagtgttag gcgcttgcgg
     5401 cgcagatgac aacggaagct caaactcttc ttctgaatca tctacagcac aatcttcgac
     5461 tgcaaaaagc acaacagaat catctgcaaa agttgtagct ggcggagatt tgcaagacgg
     5521 cacatataaa ttagaagaaa aaaattattc aaatggttac cgtgcagtct ttgaaatggt
     5581 tgtaaaagac ggcaaaatca ctgaatcaaa atatgataac gtcaatgaaa acggcgaatc
     5641 aaaaacaaaa gatgcagaat acaacaaaaa catggaagca aaatctggca caaacccaga
     5701 aaaatacatt cctgagttga atgaccaatt cttaaaagca caaagcgcaa gcggtgtgga
     5761 agtcgtaact ggagctactc actcatctga aagcttccaa aactacgcac aacaattgat
     5821 ccaagctgct caagctggta acacagatac aatcgaaatc gacaatggtg ctgatttgaa
     5881 agacggcact tacaagcttg aagaaaagaa ctactctaac ggctaccgtg tgcaattcga
     5941 aatgacagtt gctggcggca aagtaactga atcaaacttt gattatatcg acaaagacgg
     6001 taaatcaaaa caagatgata cagaatataa tgaaaatatg aaagcaaaaa gcggtacaga
     6061 accaaaaact tacatcccta ctctgaacga cgaattcgtc aaagcaatgg gcgaagaaga
     6121 tggctcacct gctaatgtag aagttgttac aggtgctaca cacagctcac attcattcat
     6181 catgtacgca caacaattag tgaatgcagc tgaaaaaggc gacactcaaa caatcgaagt
     6241 agataatatc gtaacagaaa aataatcaca taatcatact aataaaagtt ggagggtggg
     6301 acgatagcca gattaggcag tcgtctcacc tttcaaaatg aagagaggaa aaagatgcgg
     6361 aaaaaactac tattttcctt aatcacactg ggcatctctt ttatggtgct aactggctgc
     6421 agcaactcag caaataaaac aaccactgaa agttcagcag ctaccaagat attgaaagat
     6481 ccatattctg atgaacagtt cttgttaggg acttacgttc gtatccgtgt gtatgatgaa
     6541 ggcaaagaat cagcattgaa acctgccttc gatcgagtaa aagaacttgg tgataaaatc
     6601 acgatcaatc aaaaaggttc tgagatcgat gaagtgaatg agcaagctgg gatcaaacca
     6661 gtaaaagttt ctgatgacgt ctacacgtta gtcaagcggg cctacgaata tagccaagat
     6721 tctcaaggcg gattcgatat ggcgattggt gcaatcacac aattatggcg aatcggtttt
     6781 gatgacgcca gaaaaccttc ccaagaagaa atcgatcagg cattgaaatt agtggattat
     6841 cataagatcg aactaaatga caaagaaaaa actgtttatc taaaagaaaa aggaatgatc
     6901 atcgatttag gtgcaatcgc caaaggttac attacggacg aagtagtgaa agtcttgaaa
     6961 aaacaaggag tgaccactgc catcgttgac ttgggcggta atgtctatgt cttaggccac
     7021 agcccaagag gcgaaaacca agactggaca gtcggcatcc aagatccgaa catggctcgc
     7081 ggatctgttt taggttctat taaagaacgg aacaaaacat tagttacctc tggaatttac
     7141 gagcgttatt tagaagtaga tggcaaaaaa taccatcatt tgtttgatcc aaaaacgggt
     7201 tatccgttcg acaatgatat cgcaagtgtc acgatcataa cagataaatc aattgatggt
     7261 gacgggttgt ctacagcagt cttttcaatg ggtgtgaaaa aaggactgga atacgtcgaa
     7321 agcgaattga ataacgggac ggaagcgatc ttcgtgacaa aagacgataa agtatatgtg
     7381 accgatccaa tcaaagacac cttcaaatta tcggaggact cccattacac gatgggtgac
     7441 cgttctgaac taaaataagg agtacgaacc atgacactaa aaatcttttt agaagtagtt
     7501 gaaatacgaa caaaggtggc tagtgtattt ccttttgcgg taggggtatt attctctatc
     7561 gctttttttc atgagataca ttggctaaac acttttttat tttttattgg aatgctagtt
     7621 tttgatttag cgactaccgc tatcaataat tacatggatt atgaaaaggc tcattctgaa
     7681 gtatataagt atgaagaaaa tgtcattggc cgcagaaatc tatctcctgt attgattcga
     7741 aacatgattt tagctatgat tgcatttgtt tttgttatcg gcgttattct aacgatcaat
     7801 acgggttggc ttttactttt gatgggattt atctgttgtt ttattggagt attctataca
     7861 ttcggaccga ttcctttatc tcgaatgcct ttaggggaaa ttttcagtgg ggtgactatg
     7921 ggccttggaa tttttgccat ggtcgtttat gtcaatacat tcggttcaga tgtctatgat
     7981 ctgacagtca acttttcatc tggacaattt gctttggtag gaaatctttg ggctatagca
     8041 gcaatcgtat tagcttcctt acccttggtg tttacgattg ccaatatcat gttggctaat
     8101 aatttgcggg atcttgaccg tgatattgaa aatcatcgct atacactagt tttttatatc
     8161 ggacgtcctg cgggaacagt cttattccag ctattgatgt atgcttgcta tttcgtgatt
     8221 ttaatggggt tgttgagcgg tatctatgaa tggccgatct tggtcacctt cttgaccttg
     8281 ccaattgtga agaagcattt ggatcaattc aagcaaacgt taccccagcc tatcagtttc
     8341 agctattcca tcaaaaatat ggtcttattc aatgccagtt atgtattggg gctattacta
     8401 acaatcatta tgcaagccat ttaacagcat gaagaggttg tgaaaaaact gccctgcatc
     8461 aagtaataag aacagccaaa taaaaatagc tccttatatt tttcgtttgg ttgggcttat
     8521 taccgcagat gcaagctttt gaacaccgtt tatcaggagg ttgtgaaaaa gtcgcttagt
     8581 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac atttttgcat aaatttggct
     8641 taataccgag aaactggctt ttgaacaccg tttatcagag gttgtaaaat cagtgttttg
     8701 tcctgagtat tagagaaaca aatggaaaaa tagttcctca tattttgccg ttttttgagc
     8761 taataccgaa ggacagctga ttgaacacta tttgttcgga aaaagtgact aactatgaca
     8821 caattttttt cacagtccct tttttcactt gatttgattc gtaccagcga acttgacgag
     8881 aactttcttg gtttggtaac tatatggtat tcttttaaca tcctcgtttg cttcttctaa
     8941 tttatttata caaagtcaca cttttttaaa catctgttct tcgatacatt tctatttctt
     9001 ttaaacatcg ataccaatat tttgaactta agagtgcata ccaaatggat tcatttactc
     9061 ttcgtcagtt acgaagataa tcaaaatctc caacttccct acttatttcg ttttgagaat
     9121 tatcgaagca atcttacata aataactaaa aaacaaaaaa ccagaaaatc agtatactga
     9181 ttttctggtt ttacatggtt tgttcaataa aaagctgttg gaactgttaa tattaaatta
     9241 tcgcatcgtt acgaattctt ccgctcctgt tggatggatg gctactgtat tgtcaaagtc
     9301 ttctttagtt gcacccatct tgatagccac ggcaaaacct tgcagcatct catcgacacc
     9361 aacaccaata gcatgtaagc cgacgattct ttcttctttt ccgacacaga tcaatttcat
     9421 ttcgcatttt tggcgataat catttaatgc aaagtacatt ggggtaaagc gtgaacgata
     9481 aactttcaat tcattttcgc catatttttc caatgcttct tcttctgtca aaccaattgt
     9541 tgcaattggt ggatgcgtaa agacgactgt cggaacaagt ttatagtcaa gataagaatc
     9601 tttctttcca ttaaataaac gttctgataa acgtctacca gctgcgattg caacaggagt
     9661 cagatctaat ttaccgatca catcaccaac agcaaaaata tgttcatccg ttgtattttg
     9721 gtatttatct actttgataa accctttttt gtccaattcc acatttgtat tttccagacc
     9781 taatttttcg gtattcggta cacgtccacc ggcaaaaagt acacaatcac cagttaaggt
     9841 ttcaccattt tcaaatagca ccgtatattc gtcattgttt ttagtaattt ctttagcaat
     9901 atgatgtgcg taagttttta ttccagcttc ttggtacatt tggatcaaat tgtccgaaag
     9961 cattttatca aacgttctaa gtggtcgttc ttttcgatat gcccacatga cttcactacc
    10021 taaaccacaa aatacacctg aaagttcagc cgcaatgtat ccagcaccta aaacgattgc
    10081 tctcttaggt aactctgtta attcaaaaaa tccatttgaa tcaattgcgt attctccacc
    10141 aggaatggtc attttacttg cacggcctcc agtagcgatc aagattttag gagcacgata
    10201 ggtttcaccg tttacttcga tcgtttgact atcgataaaa gtagcgtaac cttttatagc
    10261 ctcgacatga ttgctatcta atcctctttg ataagcaccg tgtagaaaat caatatattt
    10321 ttctcgtctt tctactagac cggcgaaatc aacatttttt aaatctgctt ggataccgta
    10381 acttgaggca tctcgttcaa ttgtttccaa aatcgtactt gctttccaca taactttttt
    10441 aggtacacaa ccgacgttga cacatgttcc gcccaattca ttcgcttcaa tcagcaaaac
    10501 ttttgcgcca tgcatccctg ctctgtttgc tgaagcaata ccgccagagc cgccaccaat
    10561 tacgatgtaa tcatatattt gcattttgtt cctccttatt gaagagatca atcaaaacct
    10621 ttatttaacg atcctttttc tacagaaaac aagtgtaaca cttttcttga attttgtatg
    10681 cgaagatgct taaaacaggg atatatcagc tttttcctta tttacgtttt cggatcatat
    10741 ctccaggttt caccggctgt gcgactggca tagttaaaat catcattgga tttggtgctc
    10801 ggtcaatgga ttcgccttct tcattatgca taacttcaac ggtttgactg aaatgactga
    10861 atcctggacc ataaaattcg atttcatctc ctacagaaaa caagtttctc tgacgtatcg
    10921 tagcaatctg tgttgcctca tcataagata atacttcacc gacaaattta tatactggga
    10981 ttttacgacg ttcaccgaat aattgttcgt tttcagttgg tgtattgtag taaaaacctg
    11041 tagctaattc tcgttgtgct actttccata actcgtcgat ccattcttgc ttgcagacat
    11101 agttttcagg atcttccata taactgtcta cagccgcttt atagacattt gacaccgtag
    11161 atacataatg gatcgatttc attcttcctt cgatcttgaa gctgtctacg ccgttttcaa
    11221 tcaattctgg aatatgttcg atcattgaca tatccactgc actcatcgag aattcttctt
    11281 ccacttcgcc tgtatcagtt aaactgtttc gttcttgacc aaaaggcata tcgaacaatc
    11341 catacttcca gcgacaagat tgagaacatc cgccacggtt tgcatcccgc atcgacatat
    11401 ggttggacaa tgtgcatcga ccagaataag agatacacat ggcaccatgg ataaatgctt
    11461 cgatttcggt atccgtattt ttacgaatct ctgccacttc ctccattgaa acttcacgag
    11521 ctaaaacgac acgttccaac ccttcttctt tccagaattc caatgtctca aaattagttg
    11581 ctgaagcttg agtggataaa tggatcggca gacctggggc ttctgtcgca caaatttcga
    11641 tcaaagctgg atcagaaaca atcactgcag aaataccgac atcacgcaaa ctgcggaaaa
    11701 attcccctgc tccatcttca tttccttcat gggtgaccat attagcagca acgtatacct
    11761 tcgcatcatg ttcttttgca aaagcaactc cttcagccat ttcttcataa gtaaaattac
    11821 ctgcacggct tcttaaacca tatgcattcc cgccaatata tactgcatct gctccataat
    11881 ggatcgcggt ttttaacttt tccagtgttc ctgctggcgc taggatttct ggtcgtttca
    11941 attttctttt tactgtcatt tctttcatca tactccttat ttgatagcag aaggatcaat
    12001 ataaaagaat cctgtatcta attcacggtt ttcaggatgc aatttactga tttcgctagt
    12061 cattttttcc gctttttctt gatcccagct accttctaaa atttgttttt ttgcttcggc
    12121 gaatagtcga gtgatgttta cgaatttttc gcctggagta aataatccgt ccaatttcca
    12181 tgtacagtaa tgatgctgat aaagttcatt caattcattc gagagattca gatcattgct
    12241 ggcaaaaata tgtgtgccat gactatcttc ataaatagaa taatgtgtct cttctttttt
    12301 aggttccgag ataaaaagac ctctttcacg atctttttgt tcgtcttgtt tcgtatagtt
    12361 atagtaattc tgtagcagtg gacgtttgga ttgatggatg catgtagcac catacacaag
    12421 ggtttctaca ggaatatcga gtttttcttc catcgccttc atctcttcaa aaggaacttc
    12481 acgagcaagt actgctccaa ctgcgccttt tttcgcccag aaattgattt gacgtgcgct
    12541 cgttactaat gtttcagcat cataaatata cggtatacgc aattcaggat tttttttcat
    12601 cgtataaata atacctgtat caccaactgt gatcacatct acgtttattt cttttaaaaa
    12661 agccaaatat tcaggtacat ttttcatttt ttcaggatga atgatcccat ttacagcaat
    12721 attcgctttt ttaccatact tgtgtgctaa ttctaccaat tgtcgctgtt cttctcgtgt
    12781 aaatgaagca ggcagacgca atccaaattg ctcttcaccg aaatatagtg tatctgcacc
    12841 tgcagcaagc aactgttctg cttgttcaat agtttctact gtggttatga gttcgatcat
    12901 aattttctcc tcctacaact tcataatagt agcatagctc taaaaacttt ccaatacttc
    12961 ttctatttaa agtcggattt ttgaaaatta tttcacaaaa aatcaaaata aagttcgata
    13021 tattctgtcc aaatataaaa agagattgtg acaaaaatct tgtcacaacc tcttaatcaa
    13081 gtcttactat tataaaaatt cagctacaca ggccaagtaa ctatagggaa cctactgttt
    13141 cctttttagg tccgcgaaca ttcaatgtga tcttaccttt tgaagcacct actgttacgt
    13201 ggtcacctaa acgaatttct ccgccaagca aagcctcgct caatcgatct tcaatttctt
    13261 tttgaagtgc gcgacggatt ggacgtgcac catattcagg atcaaatcca gctttcccga
    13321 tcacatcgat tgcagatggt gtgattttca cttgaatatc ttgttctttc aatcgtttga
    13381 taatcgcttt gctcatgatt tggacgattg tatggatttc atctttactc aatgaatgga
    13441 agacgacagt ctcatcgatt cgattcaaga attcaggtcg gaaagctttc tttaactctt
    13501 ctaagatacg tttttgcatg gctttgtgat ctttagtaac atcttggaca ttgaatccga
    13561 catttttttc ttctcgaatt tgtgtcgctc cgatatttga agtcataatc atgattgtat
    13621 ttctaaagtc cacttttcta cctttagaat ctgttaaatg accatcatcc aatacttgca
    13681 gaagtaaatt gaaaacgtct ggatgtgctt tctccacttc atctaagaga atcactgaat
    13741 atggtttttg acgaattttt tctgtcaact gtccaccttc atcataccct acgtatcctg
    13801 gaggagaccc gattaatcgg cttgtactgt atttttccat aaattctgac atatcaacac
    13861 ggatcagggc atcttcactt ccaaacatga cttctgaaag tgctttggcc aattctgttt
    13921 ttccgacacc agttggtcca aggaacatga atgaaccaat tggacgatca ggatctttca
    13981 atccgcttcg tgcacggcgg atcgcacgtg aaactgcttt gacagcctca tcttgaccaa
    14041 cgacacgttc atgcagaagt ccttccagtt ctaacaagcg ttcgctttct tttttctcca
    14101 actgctgtag agggacacca gtccactccg atacaactgt agcaacatct tcttctgtta
    14161 cacgatcaga ataaccttgc tcctgttttg cttcaattgc agaaactttt tgcagctttt
    14221 tacgtagtgc tttttcttgt ctgcgtaatt gagcagcatt ttcaaagtct tgtttttgga
    14281 tcgctgcttc cttttcttgt actagttcat cgatttctag tttgatcaca gttgattttg
    14341 ttaagtgatc ggtttgatcc aaacggactt tcgctgctga ttcatcgatc aaatcaattg
    14401 ctttatcggg tagttgacga gaagtgatat aacgaacaga aagattgact gctgctcgta
    14461 cagcttcatc tgtgatctcc actccatggt gctcttcata tcttgtacgt aatccttgaa
    14521 gaatcacttc tgcttcttca ggagttggct catctacttg aatgcgagca aaacgtcgct
    14581 ctaatgcaga atctttttcg atatattttt gatattcatc tagggtcgtt gctccgatcg
    14641 tttgtaattc tcctcgagct aacgccggtt tcaagatatt cgaagcatca attgctcctt
    14701 ctgctccacc tgcaccaatt aaggtatgca attcatcaat gaataagatt acttgaccat
    14761 cattatagat ttcgtcgatg acctttttca ttcgatcttc aaattcaccg cgatatttcg
    14821 taccagcaac caaagatccc atatcaagca tcatcaggcg cttttcttgc atgtcttctg
    14881 gcacttcacc taaaatgatt ttttgagcta acccttcagc aatggctgtt ttgcctacac
    14941 caggttcacc caccagtaca gggttattct ttgtccgtcg gctaagaatc tggataagcc
    15001 gtttcacttc tctcgaacga ccaacaactg ggtccagctt gttttctttt gctaatttcg
    15061 tcaaatcacg tgctaatgaa tctagcgtag gtgttccttg cggtgtttgc cgtttatctt
    15121 gtacatttac atttctacga cgattcattc cttttccagc agaatcacca gctagcccca
    15181 ttttttgttt cagaacttga cgggcttttg aaaggctgat acctaagttg atcatgattc
    15241 gagtagccat gatactttca tcttttaata agctcatcaa aatatgttct gttccaactt
    15301 tttgagaacc agttttcttc acttcgctgc tagctaaagc aaaaacttgt ttcattcttg
    15361 gtgaatatgg aagaaagact cctttagggt aagaacggat accaccataa ccaatcagat
    15421 gttcaatttc ttcataaatt tccgtttcat tcaaatccat ttcacgtaat acttttccag
    15481 caattccatt ttgctcgacc actaaggcta gtaaaacatg ttctgaacta actgattgat
    15541 gtttcaaccg ttttgcttct tcttgtgcaa tttctaatac tgcttgggct ctttcagtaa
    15601 aaagttcttc catctaatct cacttcccat cttcataact taaacgttcc agaaatgctc
    15661 ggagaatccg agcacgtgta tgatcttcat attcattgaa attcaatgtg ttttttgcaa
    15721 ttgcactcaa catcaagttt ccttcttttt ttgtaattat ttggtcttca taaagttttt
    15781 gaataatagc aaaagcattt ttctcactga ttgtatcatc aaataactga tttatctgct
    15841 caagtaattg ttttttatct gaaatcctta cttttgcaat tcgtatataa ccaccaccac
    15901 cacgtttgct ttctactaga taaccacgtt ggatggtaaa acgggtatta atcacatagt
    15961 tgatttgtga aggaacacag ttaaagaggt ctgccatttc aatccttcga atctcgatca
    16021 tttcactatt ttccagaatt ttctttatat atgattcaat taaatccgag gtattctgat
    16081 gtgccatctt attcattccc tttgactaat attgacctta attataacga atttgataat
    16141 agaaagaaag aagaacgctt tttgttaaat aaatccttta gaatcaacaa aaaaaaatac
    16201 ggaatatact attccgtatc
//
LOCUS       DAZKCW010000054        15887 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000054 DAZKCW010000000
VERSION     DAZKCW010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.054"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..467
                     /locus_tag="ACG84Z_002075"
     CDS             <1..467
                     /locus_tag="ACG84Z_002075"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFP9162887.1"
                     /translation="LILILLVVLVPRIFGLTPYIIEDKEMSPYYAQGNLIYVRPKNTN
                     EILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTKTYIEPGVVKKRNIIGSPI
                     FQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVELKKKRRRTQKFL"
     gene            595..1278
                     /locus_tag="ACG84Z_002076"
     CDS             595..1278
                     /locus_tag="ACG84Z_002076"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFP9162888.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1587..1660
                     /locus_tag="ACG84Z_002077"
     tRNA            1587..1660
                     /locus_tag="ACG84Z_002077"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1621..1623,aa:Arg,seq:tct)
     gene            1819..2178
                     /locus_tag="ACG84Z_002078"
     CDS             1819..2178
                     /locus_tag="ACG84Z_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFP9162889.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2301..3932
                     /locus_tag="ACG84Z_002079"
     CDS             2301..3932
                     /locus_tag="ACG84Z_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFP9162890.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(3994..4635)
                     /locus_tag="ACG84Z_002080"
     CDS             complement(3994..4635)
                     /locus_tag="ACG84Z_002080"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFP9162891.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4821..4897
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            4917..5225
                     /gene="rplU"
                     /locus_tag="ACG84Z_002081"
     CDS             4917..5225
                     /gene="rplU"
                     /locus_tag="ACG84Z_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFP9162892.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5252..5596
                     /locus_tag="ACG84Z_002082"
     CDS             5252..5596
                     /locus_tag="ACG84Z_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFP9162893.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5609..5902
                     /gene="rpmA"
                     /locus_tag="ACG84Z_002083"
     CDS             5609..5902
                     /gene="rpmA"
                     /locus_tag="ACG84Z_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFP9162894.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6336..9143
                     /locus_tag="ACG84Z_002084"
     CDS             6336..9143
                     /locus_tag="ACG84Z_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9162895.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9334..9825
                     /locus_tag="ACG84Z_002085"
     CDS             9334..9825
                     /locus_tag="ACG84Z_002085"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFP9162896.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            9928..10917
                     /locus_tag="ACG84Z_002086"
     CDS             9928..10917
                     /locus_tag="ACG84Z_002086"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFP9162897.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            10950..11753
                     /locus_tag="ACG84Z_002087"
     CDS             10950..11753
                     /locus_tag="ACG84Z_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFP9162898.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11774..12688
                     /locus_tag="ACG84Z_002088"
     CDS             11774..12688
                     /locus_tag="ACG84Z_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9162899.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12771..13145
                     /locus_tag="ACG84Z_002089"
     CDS             12771..13145
                     /locus_tag="ACG84Z_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFP9162900.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13284..13529
                     /locus_tag="ACG84Z_002090"
     CDS             13284..13529
                     /locus_tag="ACG84Z_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFP9162901.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13701..14765
                     /locus_tag="ACG84Z_002091"
     CDS             13701..14765
                     /locus_tag="ACG84Z_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFP9162902.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15011..15436
                     /locus_tag="ACG84Z_002092"
     CDS             15011..15436
                     /locus_tag="ACG84Z_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFP9162903.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15429..15878
                     /gene="nusB"
                     /locus_tag="ACG84Z_002093"
     CDS             15429..15878
                     /gene="nusB"
                     /locus_tag="ACG84Z_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFP9162904.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
BASE COUNT         5074 a         2635 c         3476 g         4702 t
ORIGIN      
        1 ttttaattct tattcttctc gtcgtcttgg ttccccgaat ttttggtttg actccttata
       61 ttattgagga caaagaaatg agtccatatt atgcacaagg aaatctgata tatgtacgac
      121 cgaaaaatac aaatgagatt ttagtcggag atattattac atattatgaa aattcaggaa
      181 aaaaaatctc gacgcgtcgc gtaatagccg ttgaaaacaa ccacgaagat ttttatacaa
      241 aagctgatac aaagacttat attgagcctg gagtagtaaa aaagagaaat attatcggta
      301 gtcccatctt tcagattcca tatattggac tagtcctttc aaaaacggca tttgcatgga
      361 ttcaggggtt attctttacg attgcttttt gcctaacagg aatcacagca tggaatacct
      421 ttgtagagtt gaaaaagaag cggagacgaa cacagaaatt tttgtaagaa tgttaaaaac
      481 ataaatgtat tccagagatc caacgactct tctgaacatg aaacacgaga aaacactcat
      541 gcagcttgta gatttagtca gttgttcgta taatgtgtga agaggaggag tagtatgcgc
      601 aatgaaatga tgcatcgtcc tgtagtcaaa gaagaactat tggattttat gcgtacccag
      661 caaaaaaaat taccgggtga gctaggcaaa ctggaagaag aagctcatgt agcagaagta
      721 ccagttattc cccatgaaac agttgtattt ttgaaatttt tacttggaca gcttcagcct
      781 gaacgaatct tggagatcgg agcagctatc ggtttttcat caagtgtcat ggccacgaca
      841 atcggagaaa acgctcatgt tacgacaatt gatcgtttcg atgtcatgat cgagaaagct
      901 aaaaaaaact atgaacgtct aggactgaca gataaagtga ctttgcttga aggtcaagca
      961 gcagatatct tgccggagtt gtctggtccg tatgacttta tttttatgga tagtgcaaaa
     1021 tcaaaatata ttgaattttt acctgaatgc ttacgtttgt taagaaaagg tggcgttttg
     1081 atggtagatg acatcttcca aggaggaacg atcttgctcc cagatgaaga gattccccgt
     1141 ggcaaacgag ctatccatcg taaattaaat gaatttcttc gtgttgtgat ggatcatccc
     1201 gatttgacat cgacaatctt gccattaggt gatggtgtga tcttaatgac aaaggaatca
     1261 gaaacaatcg agttgtgata catgattatg gcagcctgta gataatcgat tgaatcgagg
     1321 gctcaattcg aacttgatgt aaaagtttct atatttgtaa gtcaattaaa ggatacagga
     1381 aatctaaata aacaggagta gcatgaagtc aatgtagctc ctgttttcaa ttgataacct
     1441 tagaacagct gaaggagaat gtctcgtttt aaaagattga tttagtagtt gggccaaaat
     1501 aattcattat ttgctaatta aataactatt tcgtattgac agaagcaatt taattatcta
     1561 taattattga tgttccgctg attcttgtca tagtagctca gctggataga gcatccgcct
     1621 tctaagcgga cggtcggggg ttcgaatccc tcctgtgacg ctaaaaaacc gttagaaact
     1681 gaggtttcta acggtttttc tttgtttttt gtgccaatat tgtttgtttt caaaggcaaa
     1741 taaaataaaa aaacatcctt atcgagtaca attataagga gcaaaaaaat aaaactcatc
     1801 agaaaagagg aagaagatat gacgatacta tctagaattt tagtgactct agttgcaatt
     1861 gaattttttt atatcatgta tatcgaaacg gtgagaactg attctgacac gacaagtagg
     1921 gtttttaaaa tgagtaaaga agagttaagc agaaaatctg ttcaaacatt gtttaagaac
     1981 caaggagtgt acaatggact attaggagtg ggactacttt atggagctta tctttcttcc
     2041 gcatctaaag aaatcacaag tatgctatta atatctattt tttttgttgc attatatggc
     2101 agtttgacta gcgatcgttg gattttactc aaacaaggtg ggctagctct gttggcattg
     2161 ctttctattt tcttataaat atagaaaaaa taagaattta tctaacagga aactttgtga
     2221 aaaatattac tttatctcat gaaatatgat attctaatga atggtatttt agaaaatttc
     2281 atgaaaaagg agttagatag gtgttcaaaa attatgtttc ctcactaaaa aaagaatttt
     2341 caggttatga tctttcaaga tttcagaaag atcttttggc tgggatcaca gtagctgctg
     2401 tagcattgcc tttagccttg gcttttgggg tatcaagcgg agctgatgcg gccgcaggtt
     2461 tgattacggc tatcattgcc ggtatcgtta ttggcggttt atcaggcggt ttttatcaaa
     2521 tatcaggtcc gacaggtgcg atggcagcta tcttgatgtc tattgcggca acaaagggaa
     2581 tgcaaggtgt attgcttgct acttttttag cgggtctatt tttacttgca gcaggacttt
     2641 tccgattagg aacactgact tcttttatcc cagcacccgt aattacgggg tttacttcag
     2701 gtattgctat cattattgca ttaggtcaga tcgataattt atttggtgtt cactcggaag
     2761 gtacaaacgt tattgaaaaa ctaagtagtt atcaaacgat aggatttccg ataaacacag
     2821 cctctttgat catgggaggg ctagtcattt tagggatgtt tatctatcca aaaaaatggg
     2881 cgaaacgaat gcctagttcg ctgctggcta tcattttggc aacagcagtt atgctattgt
     2941 tccatttacc agtagcaact gtgggtaaga ttccacaaac attgatcagt agtaatcgtt
     3001 tgaatatggg agattttagc ttttctgcct tgcaacaagt ggcagttcca gctattagca
     3061 ttgctttatt aggaatgatt gaaagcttgc tatgtggtgc ttcggctggc cgaatggcaa
     3121 ataagccctt agatagcaat caagaattaa tggcgcaagg aattggaaat ctgttgcttc
     3181 ctttctttgg cgggattcct gctactgcgg ccatcgcccg tacaagcgtg gccatcaaat
     3241 ctggtgcaca aactagatta gctggtatga tacatgcagt tgtcttactg ctctccatgc
     3301 ttgtttttgc gccagtgatg tcacagattc caatgccagc acttgcaggt gttttgattg
     3361 tgacggcttg gcgtatgaat gaatgggaaa cgatcaagga gctatttact aataaatatt
     3421 ggtcagcagt tctattgttt atccttacga tgatttgtac agttatcttt gatttaagta
     3481 ttgctatcgt gatcggggtg atcggcggct gtgtattttt tgttgtcaaa agcgctgcta
     3541 tcacgatttc attagaaacg atcgattggc aaagaatggg gctgccagaa acggaaaagc
     3601 tgaataactg gacagtagtg tatattagtg gtccactgtt ttttatgtct tcagaaaaac
     3661 tcaaaaataa attggaagaa ctaaatcatc acgatggtgt cattttctcc atgcgaggcg
     3721 taccaagtat tgatttgacg gcacgtgcag tttttgatga atttcaagaa aaagcagagc
     3781 aaagaggaca aacgattatc tatacttcct tgcagccaga agtagaaaaa caactttctc
     3841 acttgtggga acatacattc acgcatcaac atcaaacagt tgctcatgcg ttgacagctt
     3901 tacatgcgaa atatactgca attagccatt aaaacaatga aaaagaacag acaagactgt
     3961 aaactgaaga ttttatggtc ttgtctgttc tttttaatat tgctgtaaaa gtgaagctag
     4021 tacttgccag tcttgatgga taacaggtac aagggagcga ttgtagaaaa tagctgctgg
     4081 atgaaaaagt ggaagaattc gatagttttt ttctgaccat tcgtaggcat ccttttgttc
     4141 tgttaattgt aagacaggcc ctgtatagag ttgaccatga tttttggtaa ccgtatattc
     4201 tttgccaagt aaacgttgaa gaccaatgtt tccaagtgtc gcaattaatt ttggctggac
     4261 cttcatcagt tcgtaatcca atattggtgc atgcgcaaat acttcggaac gagtaggtgt
     4321 ccgatttgga taaacagttt ctgactgttg tgtccgttta ttgatccgat gagtcacgcg
     4381 atacgggcgg ctccttacag cactggtgat atacacctct tctcgtgtta agccagttga
     4441 agaaagtgcc tgcatcaatt cttttccagc ttgaccgcta aaaggaacat gcgtatcaat
     4501 ctctgttttc cctggggctt ctcccacgag catcagttta ggatgaagag gtccttgccc
     4561 agcgataaat ccttctacag gacggccgtt cattcttaaa gaagcttctt gtatcagttc
     4621 ttttgggtat tccatttatg ctcctccttt ttcttttatt ataagaataa aagaaacaca
     4681 atgcgactat tttatttggt agaactgtga ggatagaaaa gcagaagtat tgcttgaatt
     4741 tttgttttac tttttgattt taaatttagt tgactaacgg ttgctgttct ggtaagctag
     4801 tactgttgta attgtggact ccacagctac aaccgctcag aacaagtaat aagcacagca
     4861 tatgctgtca cttcggatgg cgagtctaag tatatcagaa ggaggtgctt tatagcatgt
     4921 acgcaattat taaaactggt ggtaaacaag taaaagttga agtgggacaa gcaatctatg
     4981 ttgaaaaact tgacgttgaa gcaggagaaa aagttgtttt tgacgaagtt atcttagtag
     5041 gcggagaatc tacaaaagta ggcgctccaa ctgttgcagg tgcaactgtt gaaggtactg
     5101 ttgaaaaaca cggcaaacaa aagaaagtcg ttactttcaa atacaaacct aaaaaacatt
     5161 cacaccgtaa acaaggtcat cgtcaaccat atacaaaagt ggttatcgac gcgatcaacg
     5221 cttaatagcg tttgagaaag aaggcctata tatgatcaaa ggaacattta agcgaaatga
     5281 cgcaggtcag atcgtttcat tcactttgac cgggcatgct gatgctggtc cttatggaag
     5341 tgatatcgtt tgtgcgggtg tttctgcgtt agcgatcagc actgtcaacg ggattgcctc
     5401 attagccggt tttgagccga ttgttgaaat gaatgaagaa gaaggcggtt atctttatac
     5461 cgaagtcact tcaggaatga cacaagaaca aaacaatatt gctgagattc tattagaaaa
     5521 tcttttatta ggattacaat cgatagaagc tgaaaactca gaatatatcc aaattaaaac
     5581 aattaatgat aaataggagg tgcagaccat gttgttatct atgaatctac aattatttgc
     5641 ccacaaaaaa ggtggcggtt ctacatctaa cggccgtgac tcagaatcaa aacgtctagg
     5701 tgctaaacgt gctgatggac aaacagttac aggtggatca attctttacc gtcaacgcgg
     5761 tacaaaaatc tatccaggtg taaacgtggg tatcggtgga gacgacactt tatttgcaaa
     5821 agttgatggc gtagtacgtt tcgaacgtaa aggccgtaac aaaaaacaag tgtctgttta
     5881 tccagtagct caagaagctt aattgaatct tatgattaaa gaggttgtga caagactttt
     5941 gtcacagcct tttttgttta taaaaataaa agttgtagtg gaggctacga agtttacttt
     6001 gtctttttac acttaatatt tttttgccaa tttggaatca ggatgttttg ataactatcg
     6061 ttttcaattg atggaagcta tattgtttgc tatcagtgaa ataattatat ggtaaacagt
     6121 gttctttttc ttgtttccat tataaaaatc gtatcgggat ttttcgttct tttaaattga
     6181 acatttctat ctatccgcgt gttatcaaca aaacaaaatc aggtaaatag ttgacgaaac
     6241 agaaataaat acatagtatt atgttttgaa gcctaagtac aatagtctat agaaaaggag
     6301 cgataccatt ggcaaaacgc attgaccgaa tttatatgta tgtcaaagaa aaaaccgctc
     6361 atttaacaaa ggcagaatat gatcaaggag taacaacaca ggaaattgct gaagtgttag
     6421 ggattcagcg aacaaatagc agtaaagatc tgaatcagct agtgcgcgaa ggaaaactga
     6481 taaagacaga cggacgacca gtacgttaca tatatcaaac actcgttacg cacgtaaagc
     6541 cagttacaaa acatgtagtc agttacaaag aaacgccggt ctctgaagaa aaaaatacac
     6601 tccaaataga tactaaggat atctttgcaa aaatcattgg agctaacggc agcatgaaaa
     6661 attcagtgga acaggcaaaa gctgcgattt tgtatccgcc aagaggatta aattgtttga
     6721 ttacaggacc taccggatca ggaaagactt attttgcaca cgcgatgtat cattttgcaa
     6781 aagcgcatca tgtaatagat gaggaaacgg aactgattgt tttcaattgt gctgattatg
     6841 ccaataaccc tgagcttttg atgagtcatt tatttgggta cgcaaaaggt gcttttacag
     6901 gcgcagatga agaaaaaatg gggattatcg atcaagcgga tggcggtatg ctgtttttgg
     6961 atgagattca ccggttgccg cctgaaggtc aagaaatgat cttttacttt atggatcatg
     7021 gaacttacag tcgtcttggg gaaacaacga aatcccatga agcaaatgta cggatcgtag
     7081 gtgcgaccac agaagaccca ggttcttctc tattagaaac ttttgttcgg cgtatcccaa
     7141 tcaatatcaa acttccggct tttgaaaaac gtcctgcaaa tgagaaagtc gatttagtaa
     7201 aaatcatgat tgcccacgaa gcaaaccgca cgcagcgaaa gatttctttg acagaagatg
     7261 tagcaaaagc attgatcggc agtgtgacct atggaaatat aggacaattg aagtcaaata
     7321 tccagttagt atgtgcacga ggatttctaa atcatatgca atcacccgaa atctcgatca
     7381 caatcgatga tttgacagaa gggattcgta gcggattgat tcaattagca agcaaccgca
     7441 gtgcaatggc agagctttct aaaatattgg agccaaagat aactgtagca ccaaatgata
     7501 cgatcatgaa aatccaatcg gactcctatg agttacctta taatctatat gatatcatcg
     7561 gagataaagc agctttactg aagtcggatg gtttggatca agaagcaatc aatcatttca
     7621 tttctacaga tatcaacatc catctgaagt ctttctataa agaccatggt ttttctttta
     7681 atgcagacag caaattagca gaatttgtag atccgaaaat catagaagtg accaatcaga
     7741 tttatgtaat ggtcaaaaga tctttaccat atgagtttca gcaaaacttt atttatgcta
     7801 tgagcttgca tatcagttct tttttgaaaa aaatcaactt aggagaagaa cggcatacga
     7861 atgataacat ccgtgagatg gcttttgatt ttccagatga atatgctgtt gcgaaagaag
     7921 tgcgtagtta tatcgaaacg tattttcaag tggagattcc agaaagtgaa gactattact
     7981 tgaccgttct actcgtctcg ttacgggcaa atcaagcaag cggcagaatc ggtgtagtcg
     8041 ttgcagctca cggaaacagc acagcaagca gtatggtcca agttgtccaa cagttgttag
     8101 atgcagagaa cgtacgagca gtagacatgc ctttggatat ggatccgaaa acagcattgg
     8161 accgaattga acgcaatgta caagaagtag atgaaggaag cggggtcata ctcttagtag
     8221 atatggggtc ccttgcgtcg tttaattcgc aaattcaaag agacactgga attccagtac
     8281 gtactgttga tatggtaaca acttctctag ttttggaaac tgtacgaaag gtctcagtat
     8341 tagggacaga tctagatatg ttgcatgaat cattgaaaaa ttttcgaggt tacgcagaaa
     8401 tatcttctgt agaatctgtt caggaagcaa aacctattca taagaaaaaa gctgttttgg
     8461 ctatctgcgc atctggcgaa ggtacagcac aaagaatcaa agaattgatc gaacgagcgg
     8521 taaacaagcg tcaagaaaca gaattagaag ttctagcttt gtcgattgtg gaagtgaaag
     8581 aagaactgcc agttatccaa aaagaatatc agatcatagc tactactggg attactgatt
     8641 tgaatatcca agccccattt attcctttag aacgttttat tgatcaaaat atcgaagtca
     8701 ttttggatca gttgctgatg gaatcagaat tggaggaaac tgaattcatc tccctagatg
     8761 aagagtcagc taaaaatacg tgtgttgagt ttatctctga taacttcatc tttattaatg
     8821 gtagtaagtt aatcgatcca atgtggcaat tttctacaca aatctctcag acgacgggaa
     8881 tcggcgatga agaatatgga ttcaaaatca acctagtgat gcacacagca ggaatgatcg
     8941 aacgtattat tcggaatgaa ccattgactg tggaagaaaa cgaattgaca aatacaacga
     9001 atgatcctct ttatagccaa ttggcagcct cagttgttct gttggaagat cagataaaag
     9061 taaaagtgcc gatagaagaa atgtattatc tgctacgtct agtccataat cagttagata
     9121 aaaaagaata cactgtgcca tgaatacaca aaaacgatac acttttatag tgtatcgttt
     9181 ttgtgtattg gttaagaatc ctttaaattc aattagtgta tcgtaaaaaa gttggcacgc
     9241 tttttgctta tagtagtgtg tgctaggagg tggttgttca cacagaaatg ataggggttt
     9301 ctgtgaagta gtgaggaaga aggagttttg cagatggata ttcgattggc acgtatagat
     9361 gatcgtttaa tccacgggca agtcgcaaca gtttggtcga agcaaacagg tgttgaacgt
     9421 atcattgtga tcagcgatgt agtcgctcaa gataaattga gaaagtttct actaaaagaa
     9481 gctgcaccgc cggggatcac agcaaatgta ataaccgtgc agaaaatgat tcaaatctat
     9541 catagtggat tattatcacg agcaaaagtg atgcttttat tcaccaatcc ccaagatgtt
     9601 gaagcggttg tccgctgcgg tgtacagttg aagtcgttga atatcggcgg tatgagtttt
     9661 actgaaggca aatcaatgat taccaatttt gtttcagtaa atcaacaaga tattgattcc
     9721 tttcgttact tgaacagtca agaagtggag ttagagattc gaaaagtacc tgctgacagg
     9781 aaaatccttt tgatggaact actagcgaaa atcaaaaagg tgtagcaaga atggttgttg
     9841 gaaaaggtca aataattctg ttgtaatggt tagcaattat taatattttt gaatttgtta
     9901 caacaaaagt aaataggagg tataaatatg gtagggatta tcctagcaag tcatggacaa
     9961 tttgctgaag gaatcttaca atccggttca atgatctttg gcgaacaaga aaacgtcaaa
    10021 gccgtgattt tgaaaccaag tgaaggtcca gatgacttga gagccaaatt ggaagaagcg
    10081 gttgcttctt ttgataatca agacgaagtg ttattcttag ttgatttatg gggcggaaca
    10141 ccgttcaatc aatcaaacac attattcgaa gagcacaaag ataaatgggc aatcgtcagc
    10201 ggtttgaatt taccaatgtt gattgaagcc tacgcatcac gcttttcaat ggaatctgct
    10261 catgaaattg cagcacacat cattgaaaca gcaaaagacg gtgtaaaagt aaaaccggaa
    10321 gaattagaac cggcagaagc accgaaagca gcagttgaag acgcacaacc taaaggagca
    10381 cttccagaag gaactgtggt cggagacgga aaaatcaaat atgtattagc acgtgttgac
    10441 tcacgtctgt tacatggaca agttgcgaca gcttggacaa aagcagtgca accaaaccgt
    10501 attatcgttg tttcagatgc agtatcaaag gatgatctgc gtaagagact aatcgaacaa
    10561 gctgctcctc caggtgtaaa agcaaatgtt attcctatta gcaaaatgat cgaagtagca
    10621 aaagaccctc gttttggaaa taccaaagca ttgcttttat ttgaaaatcc tgaagacgta
    10681 ttgacagctg ttgaaggtgg cgtagacatc aaagaattaa atgttgggtc aatggcgcat
    10741 tcggtcggta aagtcgttgt aagtaaagta ttgtctatgg gacaagaaga cgttgaagcg
    10801 tttgagaagc ttgaacaaaa aggtgtgaaa ttcgatgtac gtaaagtacc taatgattca
    10861 cgcgataaca tggatgatat tttgaaaaaa gcaaaagctg aattagcaaa agcgtaataa
    10921 ataatattaa aatttatagg aggcttatca tgtctattat ttcaataatt ttagtcgtat
    10981 tagttgcctt tctagctggt atggaaggta ttcttgatga atttcaattt catcaaccac
    11041 tagtggcatg tacattgatc ggtttagtta ccggtaacct cgaagctggt atcgtacttg
    11101 gcggtacgct tcagatgatc gctttaggtt gggcaaatat cggtgccgct gtagcaccag
    11161 atgctgcatt agcatcagta gcatcagcaa ttattttagt tttaggtgga caaggtgtta
    11221 aaggtgttcc ttctgcgatc gcgattgccg ttcctttggc tgttgcaggg ttgttcttaa
    11281 caatgatcgt acgtacaatc gctgttccaa tcgttcattt gatggatgcg gctgctgaag
    11341 aaggaaacat ccgtaaggtt gaaatgtggc acatcattgc tgtatgttta caaggggttc
    11401 gtatcgcggt cccagcagca gcgttgctat ttatcccagc acaaactgtg caatcattcc
    11461 ttgaatcaat gccagcatgg ttaacagatg gtatggctat cggtggggga atggtcgtag
    11521 ctgtaggtta cgctttggta atcaacatga tggctacaaa agaagtatgg ccattcttcg
    11581 ttattggttt cgttgtagct gcaatttctc aattaacatt gattgctcta ggtgctttag
    11641 gtgttgcatt agctcttatt tacttgaacc tttctaaaat gggtggttca tcaaataatg
    11701 gaggcggaag caactctggt gaccctttag gcgacatttt gaatgactat taatcttgaa
    11761 ggaggaaaat aaaatggcag aagaaaaaat caaattatca aaaaaagatc gtttagctgt
    11821 tgcgtggcgc tctaccttca ttcaaggttc atggaactac gaacgtatgc aaaacggtgg
    11881 ctgggcattt tctatgattc cagcaatcaa aaaattatac aaaacaaaag aagaacgttc
    11941 tgcagcatta aaacgtcact tggaattctt taatacacac ccatacattg cttctccaat
    12001 tttaggggtt acattggctc tggaagaaga acgtgcgaat ggcgcgcctg ttgatgatgt
    12061 agcgattcaa ggggttaaag taggtatgat gggtccttta gctggtgttg gtgacccagt
    12121 gttctggttt acagtacgtc caatgctagg tgcactaggt gcttcattag ctatgggagg
    12181 aaatatcctt ggaccaatca tcttcttctt aggttggaac attattcgtt gggcattcat
    12241 gtggtataca caagaatttg gctacaaagc tggttctaaa attactgatg acctttctgg
    12301 cggattgtta caagacgtaa caaaaggtgc ttcaatttta gggatgttcg tattagctgc
    12361 ccttgtacaa agatgggtat caatcaaatt cttaccagtt gtatcaactg taaaattaga
    12421 taaaggtgct tacatcgaat gggataaatt gccttcaggt ggtgaaggaa tcaagagtgc
    12481 atttgaacaa gttaataatg gcttagccct ttctcctgaa aaggtaacaa cattacaaga
    12541 caacttagac caattgattc ctggtttagc tgcattagga ttaacattgt tatgtatgtg
    12601 gttgcttaag aaaaaggttt ctccaatcgt tatcattctt ggtttattcg tagtcggtgt
    12661 tgttggacac gtcatcggac ttttataatc cataaaaata tagctcgggc gttgtcccga
    12721 gcttttttta tatagtatac tgttcataaa caaatatctg gagggagaaa atggttcaat
    12781 caatcaatac aaaagtagac ttggtaattg atgctacttc gtttacgggt ctgacagatt
    12841 acgggcaaat catgataggt gataatggtt ttgagtttta ccatgcgcga gatagacgca
    12901 aatatatcca aattccatgg gaagaagtgg attatgtact agcatcagtc atgctaaagg
    12961 gaaaatggat tcctcgatat gccattcaaa cgaaaaaaaa tggtacatac acattttctt
    13021 ccaaagaacc taaaaaagtg cttcgtgcga tcagagaata tgtagatgaa gatagaatgg
    13081 tacaatcatt gagtttcttt gatgtagtga aacgtggtat tcgtagtatg tttaaacgca
    13141 agtaaaaaat aaagaaaact tctaagagga ggttttcttt atttttttac tttgcagaag
    13201 aaaatatgaa atagcaaaac caattatttg tcccctttaa atcccatatg ctaaaattga
    13261 ttagcaaaga aggaggttat attatgagtt ggttatggac attgattgtt ggagccgtga
    13321 tcggagcaat tgcaggtgcg atcaccagta aaggaaattc gatgggctgt gtaacgaata
    13381 tcattgctgg actagtcggt tcaagtattg gacaagcgat tttcggcgaa tggggaccaa
    13441 aagctgcagg tatggcactt attccatcta ttttaggcgc agtgattttg gtagcagttg
    13501 tctcattttt ctttggaaaa cgatcataag tttttacaaa atagtaaact aaaaggagtt
    13561 gcagcgagac tgtgactcct ttttggcttt atttatttaa aataaaaaga agttttccgg
    13621 aaatttttat ttaactgtcg tgtacgaaga aaagtttgct ataatggaaa aaagcgtgca
    13681 aagaaagagg gagtttcatt atgatgctac gtgtagaaaa attgcgcaaa aaaatgcaag
    13741 aagaaaattt ggattcattt ttggttacca gtccgtacaa tcttcgttac ttaacgaact
    13801 ttacaggtac gacaggatta gctgttatta ctttggaaaa agcatttttt attactgatt
    13861 ttcgttatac cgagcaggcg gcagcgcagg ctcaagggtt tgaaattatt aaaaatgtcg
    13921 gacctatttt tgatgaggta gcaaacttag tacgcaaaga agaactgcac tcattagctt
    13981 ttgaggaaac aacagtctca tttttagaat attcggtttt agaagaaatc atcgatgcgg
    14041 aattagtacc tgtttcacag atgatcgaag aactcagaga agtgaaagat gaagaagaaa
    14101 tcgctattat cgaaaaagca tgtcatattg cggatatggc atatgatcac atcctgaaaa
    14161 tgatccaacc gggcatgact gagattgaag tcgcaaatca actagacttt tatatgcgtt
    14221 ctcttggcgc ttcaggtgtt tcttttgata cgatcgttgc tagcggattg cgttcggcta
    14281 tgccgcatgg tgtagcaagc aaaaaaatca tcgaacaagg tgacttgatc acattggact
    14341 ttggttgcta ttacgaaggg tacgtttccg atatgacacg tacattcgct attggtgatc
    14401 ctggggaaaa attaaaagaa atttatcaaa tagtcttaga tgctcaatta gcagttattg
    14461 atgctgcaaa accaggaatg actggtgtcc aattagatgc agttgctaga gattatattt
    14521 caaaacatgg ttacggggaa gcatttggac attctacagg acatgggatc ggtttagaga
    14581 tccacgaagg accaaacgtt tcttctcgtg cagaaaagca atttgtacca ggaaatgtga
    14641 tcactgatga accagggatc tacttaccag gaatcggtgg agtacgtatt gaggatgact
    14701 tgttgatcac agaagatgga aatcgtgtgt tgactcgttc accaaaagaa ttgatcatct
    14761 tatagtttca tcaatagaag aagtaagcgt aaaaatcagt gttcacagac tttgttatag
    14821 aaaatcactc gatttaatga tacactatag aagaactttt aagctgtaag agataataaa
    14881 gttgggtgtt ttctccaatt catagcagtt tgcagctgat cggcggcagt tttcttacca
    14941 cgtgatcact atgccgcatc atagagaatt cggatgtatc tcgtgcttag gcaaagggag
    15001 gaataaataa atggcagatg aaaaaaattt gattttaaac gcaaaccaag atttaggaga
    15061 gatcgtgatc gctcctgaag tcatcgaagt aattatcggg attgcagctt ctaaagtaga
    15121 aggcgtatac ggaatgcgcg gaacttttgc cagcaatgtc actgaattat taggacgtgc
    15181 agctcacgga aaaggtgttt acttagcaaa cgaggaagat ggcttgaaag tagatcttta
    15241 ctgttatcta gaatatggtg tttcagttcc taaagtagca atggaaatgc aggaacgggt
    15301 cagccagcaa gtccttttca tgacggatat cgatttatct gaagtcaata tccatgtagt
    15361 agctgttgtt cctgaaaaat tagaacaacc aacaatcgaa gaactttttg aagacgaaga
    15421 ggaagagaat gaataaagaa ttatcaagac acgagattcg ggaaatggca ttgcaggctt
    15481 tatttccatt agacttcaat gcagacctaa caaaagaaga tgcgattttc aacgcaatcg
    15541 aattagacca ccgcgacatg atcaacgaag atgaatcaga gtttgttcct gtttatcttg
    15601 atacgctagt tggcggtgtc tgtgcaaaaa aagatgaatt ggataaagtg attgaaaaac
    15661 atttaaaaaa caattggcac atcaatcgga tctcaaaaat ggatttggtg atcttgcgta
    15721 tcgcgatttt tgaaatgact tatgtgacag atgtaccagc ggctgttgct ttaaatgaag
    15781 caatcgagtt ggcaaaaaca tttagtgatg accgttcacg taaattcgtc aacggtgttt
    15841 tatccaatgt attgaaagaa ttagaagctg gggcgtaagt cctagct
//
LOCUS       DAZKCW010000055        15745 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000055 DAZKCW010000000
VERSION     DAZKCW010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15745
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.055"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            54..626
                     /locus_tag="ACG84Z_002094"
     CDS             54..626
                     /locus_tag="ACG84Z_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFP9162905.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            771..1475
                     /locus_tag="ACG84Z_002095"
     CDS             771..1475
                     /locus_tag="ACG84Z_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFP9162906.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1703..2041
                     /locus_tag="ACG84Z_002096"
     CDS             1703..2041
                     /locus_tag="ACG84Z_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162907.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFNITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2026..2880
                     /gene="lgt"
                     /locus_tag="ACG84Z_002097"
     CDS             2026..2880
                     /gene="lgt"
                     /locus_tag="ACG84Z_002097"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFP9162908.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3027..3260
                     /locus_tag="ACG84Z_002098"
     CDS             3027..3260
                     /locus_tag="ACG84Z_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFP9162909.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3458..5362
                     /locus_tag="ACG84Z_002099"
     CDS             3458..5362
                     /locus_tag="ACG84Z_002099"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9162910.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISVGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPTEKVKIS"
     gene            5716..6081
                     /locus_tag="ACG84Z_002100"
     CDS             5716..6081
                     /locus_tag="ACG84Z_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFP9162911.1"
                     /translation="MTAEVCTTTCIHKEKVASVKNNLKDKDLSTLLVLGKCFSDSSRI
                     KIFYALETYKEMCVCDLAAILNASIATTSHHLRFLKKNGMAKSRQYGKVVYYSLANED
                     ILSAIHVFLKLSENLSMKS"
     gene            6098..6711
                     /locus_tag="ACG84Z_002101"
                     /pseudo
     CDS             6098..6711
                     /locus_tag="ACG84Z_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010620830.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
     gene            complement(6823..7143)
                     /locus_tag="ACG84Z_002102"
     CDS             complement(6823..7143)
                     /locus_tag="ACG84Z_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFP9162912.1"
                     /translation="MNSLSTSPLKNESIQEVSKIFKMISDPTRLSILFLLQKEELSVG
                     AIAHSLSMEQSAISHQLKTLKTSRLVKSKRAGKNMIYSLDDLHIFSILEQVSTHIEEQ
                     EKEK"
     gene            7399..9306
                     /locus_tag="ACG84Z_002103"
     CDS             7399..9306
                     /locus_tag="ACG84Z_002103"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9162913.1"
                     /translation="MKEIQEQHSHENNSHDHGKMPIILYFIGLALSLIALFVNGENNL
                     IQNTLFSIASISAGYHVIILEGIGETIENSKRQHKFTPNSHILMGIAAIGASLIGNFW
                     EGTLLVLIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLIMQDGNTTIVNVSELKVG
                     DQLQVLNGDQVPIDGVIVSGSTSIDESSINGESIPKEKSKGDGVFGSTINGTGTFTME
                     VTKETNDTVFSKILQLVNQNQENQTKASSIIQKFEPKYVKFVLIAIPLFILLAPMLFD
                     LTWSQSIYRGLVLLVAASPCALAAATVSVTLSATSNLAKRGVLSKGSAYLSQLADIQA
                     IAFDKTGTLTKGKPEVTNYYFSDSVNEENMIDIVVALEKESNHPLASAILDKFEPKNK
                     LAIEVENQIGKGLIGDYNENTYRIGKPTSFEAVSDDYTRLNKEWASEGNTVVYVSENE
                     KVIGLIALMDIPSEHAKATIDYFKKCGIHTTLITGDSEMTGQAVGKQLGVDQVIANVM
                     PEDKSNIINEQKETYGITAMVGDGINDAPALVKADVGIAMGEGTDVAVDVSDLVLMKN
                     DLSKLVKAHEISLKMNRVIWQNIIFSMVVVAFLITVSLVGLTDIAISVIVHEGSTLVV
                     ILNGLRLLKSK"
     gene            9400..9621
                     /gene="relB"
                     /locus_tag="ACG84Z_002104"
     CDS             9400..9621
                     /gene="relB"
                     /locus_tag="ACG84Z_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFP9162914.1"
                     /translation="MTVISLRIDTQEDKLIKEYAKAKNISVSALIRSSVLEKIEDEID
                     LGLYNQAMKDHKENPKSISFEDMLKELSD"
     gene            9622..9894
                     /locus_tag="ACG84Z_002105"
     CDS             9622..9894
                     /locus_tag="ACG84Z_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFP9162915.1"
                     /translation="MSSGYQVEFEKGAQKALKKMDKYQSLLIMGWIQKNLVNCTDPRQ
                     HGKGLTVNRSGEWRYRIGDYRLIADINDETVTILMLEIGHRKNIYK"
     gene            complement(10025..12991)
                     /locus_tag="ACG84Z_002106"
     CDS             complement(10025..12991)
                     /locus_tag="ACG84Z_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFP9162916.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            13137..13712
                     /locus_tag="ACG84Z_002107"
     CDS             13137..13712
                     /locus_tag="ACG84Z_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9162917.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            13926..14621
                     /gene="vanR-A"
                     /locus_tag="ACG84Z_002108"
     CDS             13926..14621
                     /gene="vanR-A"
                     /locus_tag="ACG84Z_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFP9162918.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            14599..>15745
                     /gene="vanS"
                     /locus_tag="ACG84Z_002109"
     CDS             14599..>15745
                     /gene="vanS"
                     /locus_tag="ACG84Z_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFP9162919.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKR"
BASE COUNT         5059 a         2657 c         3201 g         4828 t
ORIGIN      
        1 aggaatcaaa gaaagctatt ttaaacaaac caaaattata ggaggaataa atcatgactg
       61 aaaataaagc tactcaagaa agaacacccc aagaaagatt gcaagaagaa caagaacaca
      121 aggaacatgt tcatcatacg aaaattaatg cagcggccat tgcggatcat cttttaggca
      181 acatgcatac attacatgtg aaactgcacc aatatcactg gtatgtaaaa ggagccaatt
      241 tctttacgtt gcatgaaaaa tttgaagagt tgtataacga aaatgaaaaa tggttcgaca
      301 aacttgcgga gcgtctaatt acttctgggc ataaacctgc ttcgacaacg gttgaatttg
      361 aaaaatattc gatgctttcg gaagatgcag ttaataaata cgctaaagca gaagacatgg
      421 ttgaaaatat tatcgaggac ttcagaagca ctcgtgacct aactattcgc gcgattcgtt
      481 tagctcaaga cgagggtgac gatgctttag aagatacatt gattgctttt aaaaatgact
      541 tagacaagaa catttggatg ctgcaagcgt tcattggtaa agaagcatta gaagatgatg
      601 acgctcttga tgaggatgaa gattaaggta aaagtagaag ctgatttagg gattggaatt
      661 ctttccagtc ctttttccat tttcttgatg tgcatcaatt tttttgtagt aagagactta
      721 tataataaaa gcagcgaata taaacaaaat aaataaaggg ggagaatgaa ttgactaaac
      781 atacccatca tgaaattggc gaccacgcag cctgtatccg cttggttcca atattcaatc
      841 acttagagga tagcgcgatg aattacattg ctgaaaaagc ccacacgaaa cagtatcaaa
      901 aaggagagtt tctgtttcgt tcacaagaaa aagaggatac tttatatatt atcaatcgtg
      961 ggaaaatccg tatttatcga ttggcagact ctggcaaaga gcagctagtg cggatcttga
     1021 accctggtga tttcaccgga gaatggacct tgttcaaccc ggatgcagta cacgaggaat
     1081 atgccgaagc aacccgagat accgttgtct gtatgattca gcaaaaagat gtccaagatt
     1141 ttctggaaca atacccagct atttctttaa aactattggc ggaaatgtct aaacggttag
     1201 aaagttcaga acgtcaaacg acacaagtag ccgtggagag tgtcattacc cgtttagttt
     1261 tgtttttggc agaaaatgtg gaacctgaaa tgggcaactc tcccaccatc accctgccga
     1321 tggcaaaaaa ggacattgct tcctatttag gaacgacacc tgagaccatc agtcgcaaat
     1381 ttggagaatt ggaggacgag ggattgattc aacagctgtc tgggaaaagg atcaagattc
     1441 aggatttaga tgatttattg ctttacagcg aataatcgga cacacttttt tctacacgtt
     1501 ggtgttctgt cgctcttcat taacaacggg acagaactca gtgcttttgc ttccatctgt
     1561 ccgtttttag cttttttaag acagaacgac cttcattcat tggaaaaata aaagcacaaa
     1621 catgataacc ctcaagtttt tttgttttat ttttctttaa gatagggttg tcgaacaaaa
     1681 cgtaaaaata agtagggtga atgtgcattg tttttgggtg atagttgcca tcacgttgtc
     1741 agcagcgggt gcattctttg tcgtcccttt caccaagaac acgattggcg gcgaagcaaa
     1801 aacgtctaac gttgttgagg cagataggtt agctatggaa aaagaagagg aagttgtaaa
     1861 aggagccggc gtaatcggac acggaaaagt ggcgtattac gaagcgagtg accagggaga
     1921 taaaagtgta ttcactgttt ggtttccatg gagcttagcc ggaatcttgt tcaacatcac
     1981 catgactaga atgacgcgaa aaattgaaga aatggagcaa atagaatggg attcgtatta
     2041 ggcgttttga atccccatgt ggtggagatt ggttctgttg tgattcattg gtatggagtc
     2101 attattgcag cgggcatatt agcggctctc cagttgagca ccaaggaagc aaagaaaaaa
     2161 ggactggaag aggataccat tatcgatatg gccttatggg caattccgat tggactcctc
     2221 ggcgctcggc tttattatgt gttatttgaa cttggttatt atctgcaaaa tccaggacaa
     2281 atccttgcga tttggaatgg cggcattgcg atttatgggg gattgattgc aggagggggt
     2341 acgctatatt ggtatgcaaa gaaaaaaggt acttctttgg cactcgttct tgatatttta
     2401 gcgcccaatg tattgttagc ccagtccatt ggtcgttggg gcaattttat gaatcaggaa
     2461 gctcatggtg ggccggttac tcgtcaattc ttggaaaatc tttatttacc tgaatttatc
     2521 attgaacaaa tgaatatgaa tggtacctac taccatccga cttttttata cgagtcattg
     2581 tggagtttgt tgggctttgt cctcatcgtc actatacgga accgaaaaca gcttttgcgt
     2641 caaggagaag tcgctttgag ttacgttttg tggtactcag tgggtcggtt cttcattgaa
     2701 ggtatgcgaa cggacagttt atggattggc gagtggatcc gcgtttcgca agccttgtct
     2761 ctggccctgt ttattggcgc gattgtagta tggtttatac gcagacaaga ttatccacca
     2821 atttcttatt attctgatgg caataagggg cagaaaaaga ctattaagat ggtgaattga
     2881 gcaaaaagat aaaaagaagt gcaaaacttg atatgcgtca attttcgttt gctaaaagtg
     2941 agctatacta cagttgtaaa gaggaaaagg cagtgttcat taatctgctg ccgataaaat
     3001 aaaaacacat aaaggagata ggaattatgg aaaaagctat attgcaatta gaaacgttgt
     3061 cttgtccaag ttgtatgcaa aaaattgaag gtgccgtgaa atcagttaac ggtattgata
     3121 aagacagcat taaagtatta ttcaactcca gcaaagtcaa aaccaatttt gattcagctg
     3181 tcacttcgat tgaagagatt caaaaagcta tcgaaaacgt aggctatccg gttcttaaag
     3241 caaaagtcaa ggccgtttaa cagattaaat gaactaggca attctggaag aaaagctatt
     3301 tttccaggat tgcttttttt gttgcaatcc gattcgaggt gcttagaaac gataaaagag
     3361 aactttctaa acttgatgtc agtcaattaa ttacttaggc aattatctta tactgtgttt
     3421 atcaataaaa gagaaattaa atttggaggg aaaaagcatg caacaatata tattaagcaa
     3481 gaaaaatgtt atcaccgtca tcagtggatt gttaatcgta ctcggtttct tcagtcactt
     3541 tgttttagaa aacgtaggac tttcagagtg gtctttgatc atcgcctctg tctttgggat
     3601 tacgccaatt gccattcaag cgtttcaagc aatgaaagtc aaagtcatca gtattgatgt
     3661 cttagtcagt attgcagcga ttggtgcgct ttttattcaa aattatgaag aatcggctat
     3721 tgtcacgttc ttattcttat tcggacacta cttggaacaa cgaacattga accaaacgcg
     3781 atctgctatc aaagaattga ctgaaatggc acccgaaagc gccttgaaac aaatggataa
     3841 tggcgaattt gaagaagtag aagtggatga tatagatgaa ggggatatct tgctcgttaa
     3901 aacgggtgcg aaagttccag tagatggcat agtccttacg ggtgaagggc atatcaatga
     3961 agctagcatt acaggtgaag ctattccggt caacaagcta gctgatgcag aagtttttgc
     4021 aggaaccatt ttagaaaacg gaacgattca aatcagagct gaccgagttg gtgaggacac
     4081 cacatttgga aaaattattg aactcgtgga agaagcacaa gattctaaat ccgaagcgga
     4141 acggttcatt gatcgctttt ctaaatacta cacaccagct gtcttggttc tggcaattgt
     4201 tgtatgggcg ttcagtcaaa atattgagtt agcaatcacc atcttggttc taggttgccc
     4261 aggcgcatta gttatcggag tgcctgtctc aaacgttgcc ggtattggga atggtgctcg
     4321 taacggtgtt cttttaaaag ggagtgaagt cattcaagac ttcagtaatg tggatacaat
     4381 tgtatttgat aagacaggta ctttaactgt cggaaaccca accgttgcag cgactgaact
     4441 gtatgaaaaa gatcctgctg aaacgcttgg ctatctggcc agtgtggaac gggaatcaga
     4501 tcatccatta gcaaaagcgg tcttaaatca aattggagaa acaaactttt atcctgttga
     4561 aggaactgaa gttgtgaaag gcggcggaat cgtttcaagt gtagctggac atagagtggc
     4621 tgttgggaat gtggccttga tggaaaaaga aaatgtcact ctcagcaaaa aagtgcaaaa
     4681 agatgtcaaa cggtttgaac aacaagggaa ctctctcgtt ttgacagcgg tcgacggtga
     4741 attaaaagta ctgatgggca ttcgcgatca agtccgtccg ggtgtgaaag ctaatttgca
     4801 ggaattaaaa gacttgggcg tgaaaaatct agtcgttctt tcaggagata accaaggaac
     4861 cgttgatgtg gtcgccggcg aacttggttt gaccgaagct cacggctaca tgttgccgga
     4921 agacaaatcg gcttatatcg gaaaacttca acaacgtggt caaattgtag cctttgttgg
     4981 agatggcgtt aacgatagtc cgtccttagc tttagcagac attggaatcg caatgggaag
     5041 cggaacggac gtagcgattg aaacatccga tgtcgtttta atgaactcga acttcagcaa
     5101 cttgcctcac gcattaggat tagtaaaagc caccgcaaat aatatgaaac aaaatatcgt
     5161 gatttcagtt ggagtagtgt tggtcttgtt gaccagcgtc ttcttcagcg aatggatgaa
     5221 tatgtctatc ggaatgttgg ttcatgaagg tagtatcttg gtggtaattt tcaatggcat
     5281 gagattaatg aagtataagt tgaaaggtcg gaaagaacaa aaagaagtat cagcacctac
     5341 agagaaagta aaaatatctt aagaataaat tagaagaggc tgagacaata gtccatcctt
     5401 gaaatgacaa aagcggaaac tcagattttt aaatctggga ttttccgctt ttttgagttc
     5461 ttgaaaaaaa ataagagtat agagtatgtt ctttataaaa ttaattttcg tgtaaattat
     5521 taaaaattta ataataaaat ttaaattcct attaagttgt aacacatgaa attgcttaaa
     5581 atagtgtatc aaaaaccttg ttttattaat gttgaattta tttgaaaggt ctacagatta
     5641 acatattatt gacaaaacaa tatttaaata gttatacttc attcaaacgt ctgtttgaac
     5701 gaggtggtga agttaatgac tgcagaagta tgtacaacta cttgtataca taaagaaaaa
     5761 gtagctagtg ttaaaaataa tttaaaagat aaagaccttt caactttact tgtattagga
     5821 aaatgtttta gcgattcttc taggattaaa attttctatg ctttagaaac gtataaggag
     5881 atgtgcgttt gtgatttagc agcgatactt aatgctagta ttgctacaac gtcacaccat
     5941 ttacgttttt tgaaaaagaa cggaatggcg aaatcacgtc aatatggaaa ggtagtttat
     6001 tactctttag cgaatgaaga catcctttcc gctattcatg tttttttaaa gttatcagaa
     6061 aatctatcta tgaaatctta gtttggagga agttattttg ttacaaagta ttttttcagc
     6121 tatcgctgtt tatatttcta ccagcattga ttatttgttt atcttgctga ttattttttc
     6181 tcaaagtcat acaaaaaagg gctccgtcag attttttggg gtcaatatct aggaacaggt
     6241 atcttagtag ccgtaagttt atttgcagca tatgtgctga atttcattcc gcaagattgg
     6301 atcattgggc ttctcggtct aattccgatt ttcttaggaa tcagagtggc attggttggc
     6361 gaagaggagg aagaagaaga ggaagtcgtt gaaaagcttg aatcaagagg aacaaaccgc
     6421 ttcttttgga ccgttgcctt aataacaatt gcttctggtg gcgataactt agggatttat
     6481 attccttact ttgcctcgtt atctttttca gagattgtca ccgctctaat cgtatttgct
     6541 atttctgttg cggttctttg ctatatcagt tacaaattag ccaagatttc ttttgtttcc
     6601 gaaaccttag aaaaatatga acgaatcctt gttcctatag tgtttattgg cttaggaatt
     6661 tatattttga tagaaaatgg gacgattcaa acactattaa attttatata aacaactacg
     6721 atagtgaagt tcaaataaaa aaagacagcg agattttaac tcgctgtctt tttttatttg
     6781 aactaatgaa ttgtaaaatc attttaacct tgtagtttgt ctttattttt ctttttcttg
     6841 ttcttcgata tgagttgaaa cttgctcaag aatactaaaa atatgaagat cgtcaaggct
     6901 ataaatcata tttttaccag ctctttttga ttttactaat cttgaagtct ttaaagtttt
     6961 taactggtga gaaattgctg attgttccat actcaaagaa tgcgcaatag ctccaacgct
     7021 aagttcttct ttctgcagaa gaaataaaat tgaaagtcgg gtagggtcac tgatcatttt
     7081 aaatatttta cttacctctt ggatagattc attttttaat ggagaagttg ataatgaatt
     7141 cataagaatt tctctccttc atatgtttgt ttattcacat ttagattatc ataatatttt
     7201 tataaagcaa gattttttgt ataagggtag ctattttaga gtcctatttt ttttatcacc
     7261 taaataagat aactattttt ttgacaaatt agatagagcg atataaaatg aatgtataga
     7321 catatgaatg ttcgttcaaa cgtaattcgt aagcattacg atttctaaaa aaaagtttta
     7381 ttaagaaagg tgatagaaat gaaagagatt caagagcaac actcacacga aaataatagt
     7441 cacgatcatg ggaaaatgcc aattattttg tactttattg gtttagcatt gtcgctcatt
     7501 gcgttatttg taaacggaga aaataattta atccaaaaca ctttgttttc aattgcttca
     7561 attagtgctg gttatcatgt cattattctt gaaggaattg gagaaacgat tgaaaactca
     7621 aaaagacaac acaaatttac ccctaattct catattttaa tgggaatagc tgcaataggt
     7681 gcttctctga taggaaattt ttgggaagga acgttattgg ttcttatttt ctctggagca
     7741 cattttcttg aagattatgc tgaaggaaga agtaaaagag aaattaccaa gttattagaa
     7801 atgaatccaa caacagctag gctaatcatg caagatggca atacaacaat cgttaatgtt
     7861 agtgagttga aagtaggaga tcaacttcaa gtgttaaacg gtgaccaagt accgattgac
     7921 ggagtaatag tatcaggctc tacttcgatt gacgaatctt ctattaatgg tgagagtata
     7981 cctaaagaga aatcaaaggg agacggagtt tttgggagta caattaatgg aacgggtacc
     8041 tttactatgg aagtcacaaa agaaactaac gatactgtct tttcaaagat tttacaacta
     8101 gtgaatcaaa atcaagagaa tcaaacaaaa gcgtctagta ttatccaaaa gtttgagcct
     8161 aagtatgtta aatttgtttt aattgcaatc ccactcttca ttttacttgc tcctatgctg
     8221 tttgatttga catggtcaca aagtatttat agaggattag tccttttagt cgcagcttct
     8281 ccgtgtgctt tagcagcagc taccgtatcc gtaacattgt cagccacttc taatctagca
     8341 aaaagaggcg tactttcaaa aggaagtgcc tatttgtccc aattagcgga tattcaagcc
     8401 attgcctttg ataaaacagg aacattaact aaagggaaac cggaagtaac caattattac
     8461 ttttctgatt ctgtgaacga ggaaaatatg attgatatcg tagtggctct tgaaaaagaa
     8521 tcaaatcacc cgttagcaag tgctatttta gacaagtttg aaccaaaaaa taaactagct
     8581 attgaagtgg aaaatcagat tggaaaaggt ttaataggcg attataacga aaacacttat
     8641 cgtataggta aaccaacttc ttttgaggct gtatcggatg actatacacg tttgaataaa
     8701 gaatgggctt cagaaggtaa tacggttgta tatgtatcag aaaatgaaaa agtaatcggc
     8761 ctgatagcat taatggatat tccaagtgaa catgcgaaag caactataga ttactttaag
     8821 aagtgtggta tccataccac tttaattact ggggattctg aaatgacagg gcaagctgtt
     8881 ggtaaacaat taggagtaga tcaagtaatt gcaaacgtca tgccagaaga taaatctaac
     8941 attatcaatg aacaaaaaga aacctatggt ataaccgcta tggtgggaga tggtataaac
     9001 gacgcacctg ctcttgtgaa ggcagatgtt ggaattgcta tgggagaggg tacggatgtt
     9061 gcagtagatg tatctgatct agtattaatg aaaaatgatt tgtctaaatt ggtaaaagct
     9121 catgaaattt ctttaaaaat gaatcgagtt atttggcaaa atattatttt ctcaatggta
     9181 gttgtcgctt ttctaattac cgtaagctta gtaggattaa cggatatagc cattagtgtg
     9241 attgttcatg aaggaagtac cttagtcgtg atattaaatg gtcttcgatt attaaagtct
     9301 aaataaatac atgaaattgg ataaaatcat gtatctaaag tttgcagcct ctctaatttt
     9361 gtattacaat gtatatacaa aaagaagggg gtgattctaa tgactgtcat atcgctcaga
     9421 attgatactc aggaagataa attaattaaa gaatatgcta aggcgaagaa tatttcggtt
     9481 tcggctctga ttagaagttc tgtcttggaa aaaatcgagg atgaaattga tttgggccta
     9541 tataatcaag ccatgaagga tcataaagag aatccgaaaa gtatttcttt tgaagacatg
     9601 ctaaaggagc tatctgatta aatgagctca ggttatcaag tcgagtttga aaaaggagct
     9661 caaaaagcgt taaaaaaaat ggacaaatac caatcccttt taattatggg atggattcaa
     9721 aagaatctag tgaattgtac cgatcctagg cagcatggaa aaggattaac cgtcaatcga
     9781 tcaggcgaat ggcgctatag aatcggtgat tatcgcttaa tagctgatat caatgacgag
     9841 accgtaacca ttttaatgtt agagattggt catagaaaaa atatttacaa ataaaccatt
     9901 caaattgagt gcaagcatgt ttaataaaaa aggattctac tgctttttaa ggggtagcgt
     9961 caggaaaatg cggatttaca acgctaagcc tattttcctg acgaatccct cgtttttaac
    10021 aacgttaaga aagttttagt ggtcttaaag aatttaatga gactactttc tctgagttaa
    10081 aatggtattc tcctagtaaa ttaatatgtt cccaacctaa gggcgacata tggtgtaaca
    10141 aatcttcatt aaagctacct gtccgttttt tatattcaac tgctgttgtt aggtggagag
    10201 tattccaaat acttatagca ttgataatta tgtttaaagc actggctctt tgcaattgat
    10261 gctgtatggt gcgttctcta agctcacctt gttttccgaa gaaaatagct cttgccaatc
    10321 cattcatggc ttctccttta ttcaatcctc tttgtatttt tcttcttaat gattcatccg
    10381 atatataatt caaaataaag atcgtttttt ctattcggcc catctcacgt aaggctgtag
    10441 ctaagctgtt ttgtcttgaa taggaaccta gcttccccat aataagggat gctgaaactg
    10501 ttccctccct tatagaatga gctaatcgca aaacatcctc ataattttct ttaatgacct
    10561 ttgtatttat ttgtccacgt aaaatggctt ctagttttgg atactcactt gctttatcta
    10621 tcgtaaataa ttttgagtcc gataaatccc ttattcttgg ggcaaattta aatcctaata
    10681 aatgagtcag tccgaatatt tggtcagtgt aaccggcagt gtctgtataa tgttcctcta
    10741 tgtttagatc cgtctcatga tgtaacaaac catccaaaac atgaatcgca tctcttgaat
    10801 tagtatgaat aatctttgtg tagtaagaag agaattgatc acttgtaaat cggtagatgg
    10861 tggctccttt tccagttcca taatgtggat ttgcatctgc atgtagtgat gaaacaccta
    10921 gctgcattct cataccatct gacgaagatg ttgtaccgtc gccccaatag aaaggcaatt
    10981 gtaatttatg atgaaagttt actaatatgg cttgggcttt attcatggca tcttcataca
    11041 tgcgccattg agatacattg gctagttgct tatatgtaag tccgggtgtg gcttcggcca
    11101 tcttgctcaa gccaatattc attcccattc ctaaaagggc agccatgata atgattgttt
    11161 cttccttatc tggttttcga ttattggaag catgagtgaa ttgctcatga aatcctgtta
    11221 tatgggccac atccatgagt aaatcagtta attttattct tggtagcatc tgataaaggc
    11281 ttgcactaaa tttttttgct tcttctggaa catctttttc taagcgtgca agtgatagct
    11341 ttcctttttc aagagaaacc ccatctaact tattggaatt ggcagctaac cactttaacc
    11401 tttcattaaa gctgctggtt ctctccgtta tataatcttc gaatgataaa ctaactgata
    11461 atctcgtatt ccccttcgat tgattccatg tatcttccga aaacaaatat tcctcaaaat
    11521 ccctatattg tctgctgcca acaatggaaa catctcctgc ccgaacatgc tcccgaagtt
    11581 ctgttaaaac agccatttca tagtaatgac gattaattgt tgtaccatca tcctcgtata
    11641 aatgtctttt ccatcgtttt gaaataaaat ccacaggtga gtcatcaggc acttttcgct
    11701 ttccagattc gttcattcct cggataatct caacagcttg taaaagtggc tcatttgcct
    11761 ttgtagaatg aaattccaat actcttaata gcgttggcgt atattttctt agtgaataaa
    11821 accgtttttg cagtaagtct aaataatcat agtcggcagg acgtgcaagt tcctgagcct
    11881 cttctactga agagacaaag gtattccatt caataaccga ttctaaaacc ttaaaaacgt
    11941 ctaatttttc ctctcttgct ttaattaatg cttgtccgat gttcgtaaag tgtataactt
    12001 tctcatttag ctttttaccg ttttgtttct ggatttcctc ttgagcctta cgaccttttg
    12061 ataacaaact aagtatttgc ctatcatgaa tttcaaacgc tttatccgtt agctcctgag
    12121 taagttgtaa taaatagatg gttaatatcg aataacgttt attttcttga aagtcacgga
    12181 atgcatacgg ctcgtatctt gagcctaagc gagacagctg caacaggcgg ttacggtgca
    12241 aatgactaat ttgcactgtt tctaaatcca ttcctcgtat gtattcgagt cgttctatta
    12301 tttttagaaa agtttcgggt gaaggatgac ccggtggctc ttttaaccaa cccaatatcg
    12361 ttttattgga ttcggatgga tgctgcgagg taataatccc ttcaagcttt tctttttgct
    12421 catttgttag agatttacta accgtattaa atagcttctt ttcagccatt gcccttgctt
    12481 cccacaccat tctttcaagt gtagtgatag caggcagtat aattttgttt tttcttagaa
    12541 aatctatgca ttcatgcagt agatgaatgg catcaccatt ttccaaagct aattgatgaa
    12601 ggtacttaaa tgtcattcga tattcactca gggtaaaagt tacaaagtcg tattcacttc
    12661 gaatttcttt caaatgatcc caaagtgtat tttccctttg aggataatga tcaagcgagg
    12721 atggactaac accaatctgt ttcgatatat attgtatgac cgaatctggg atgcttttga
    12781 tatgagtgta tggccaaccg ggataccgaa gaacagctaa ttgaacagca aatcctaaac
    12841 ggttttcttc cctccttcgc ttattaacta tttctaaatc ccgtttggaa aaagtgaagt
    12901 aggtccccag tatccattca tcttcaggga tttgcataaa agcctgtctc tgttccggtg
    12961 taagcaattc tctacctctc gcaattttca ttcagtatca ttccatttct gtattttcaa
    13021 tttattagtt caattatata tcaatagagt gtactctatt gatacaaatg tagtagactg
    13081 ataaaatcat agttaagagc gtctcataag acttgtctca aaaatgaggt gatattttgc
    13141 ggaaaatcgg ttatattcgt gtcagttcga ctaaccagaa tccttcaaga caatttcagc
    13201 agttgaacga gatcggaatg gatattatat atgaagagaa agtttcagga gcaacaaagg
    13261 atcgcgagca acttcaaaaa gtgttagacg atttacagga agatgacatc atttatgtta
    13321 cagacttaac tcgaatcact cgtagtacac aagatctatt tgaattaatc gataacatac
    13381 gagataaaaa ggcaagttta aaatcactaa aagatacatg gcttgattta tcagaagata
    13441 atccatacag ccaattctta attactgtaa tggctggtgt taaccaatta gagcgagatc
    13501 ttattcggat gagacaacgt gaagggattg aattggctaa gaaagaagga aagtttaaag
    13561 gtcgattaaa gaagtatcat aaaaatcacg caggaatgaa ttatgcggta aagctatata
    13621 aagaaggaaa tatgactgta aatcaaattt gtgaaattac taatgtatct agggcttcat
    13681 tatacaggaa attatcagaa gtgaataatt agccattctg tattccgcta atgggcaata
    13741 tttttaaaga agaaaaggaa actataaaat attaacagcc tcctagcgat gccgaaaagc
    13801 cctttgataa aaaaagaatc atcatcttaa gaaattctta gtcatttatt atgtaaatgc
    13861 ttataaattc ggccctataa tctgataaat tattaagggc aaacttatgt gaaagggtga
    13921 taactatgag cgataaaata cttattgtgg atgatgaaca tgaaattgcc gatttggttg
    13981 aattatactt aaaaaacgag aattatacgg ttttcaaata ctataccgcc aaagaagcat
    14041 tggaatgtat agacaagtct gagattgacc ttgccatatt ggacatcatg cttcccggca
    14101 caagcggcct tactatctgt caaaaaataa gggacaagca cacctatccg attatcatgc
    14161 tgaccgggaa agatacagag gtagataaaa ttacagggtt aacaatcggc gcggatgatt
    14221 atataacgaa gccctttcgc ccactggagt taattgctcg ggtaaaggcc cagttgcgcc
    14281 gatacaaaaa attcagtgga gtaaaggagc agaacgaaaa tgttatcgtc cactccggcc
    14341 ttgtcattaa tgttaacacc catgagtgtt atctgaacga gaagcagtta tcccttactc
    14401 ccaccgagtt ttcaatactg cgaatcctct gtgaaaacaa ggggaatgtg gttagctccg
    14461 agctgctatt tcatgagata tggggcgacg aatatttcag caagagcaac aacaccatca
    14521 ccgtgcatat ccggcatttg cgcgaaaaaa tgaacgacac cattgataat ccgaaatata
    14581 taaaaacggt atggggggtt ggttataaaa ttgaaaaata aaaaaaacga ctattccaaa
    14641 ctagaacgaa aactttacat gtatatcgtt gcaattgttg tggtagcaat tgtattcgtg
    14701 ttgtatattc gttcaatgat ccgagggaaa cttggggatt ggatcttaag tattttggaa
    14761 aacaaatatg acttaaatca cctggacgcg atgaaattat atcaatattc catacggaac
    14821 aatatagata tctttattta tgtggcgatt gtcattagta ttcttattct atgtcgcgtc
    14881 atgctttcaa aattcgcaaa atactttgac gagataaata ccggcattga tgtacttatt
    14941 cagaacgaag ataaacaaat tgagctttct gcggaaatgg atgttatgga acaaaagctc
    15001 aacacattaa aacggactct ggaaaagcga gagcaggatg caaagctggc cgaacaaaga
    15061 aaaaatgacg ttgttatgta cttggcgcac gatattaaaa cgccccttac atccattatc
    15121 ggttatttga gcctgcttga cgaggctcca gacatgccgg tagatcaaaa ggcaaagtat
    15181 gtgcatatca cgttggacaa agcgtatcga ctcgaacagc taatcgacga gttttttgag
    15241 attacacggt ataacctaca aacgataacg ctaacaaaaa cgcacataga cctatactat
    15301 atgctggtgc agatgaccga tgaattttat cctcagcttt ccgcacatgg aaaacaggcg
    15361 gttattcacg cccccgagga tctgaccgtg tccggcgacc ctgataaact cgcgagagtc
    15421 tttaacaaca ttttgaaaaa cgccgctgca tacagtgagg ataacagcat cattgacatt
    15481 accgcgggcc tctccgggga tgtggtgtca atcgaattca agaacactgg aagcatccca
    15541 aaagataagc tagctgccat atttgaaaag ttctataggc tggacaatgc tcgttcttcc
    15601 gatacgggtg gcgcgggact tggattggcg attgcaaaag aaattattgt tcagcatgga
    15661 gggcagattt acgcggaaag caatgataac tatacgacgt ttagggtaga gcttccagcg
    15721 atgccagact tggttgataa aagga
//
LOCUS       DAZKCW010000056        14847 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000056 DAZKCW010000000
VERSION     DAZKCW010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.056"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(139..1341)
                     /locus_tag="ACG84Z_002110"
     CDS             complement(139..1341)
                     /locus_tag="ACG84Z_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9162920.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1344..1538)
                     /locus_tag="ACG84Z_002111"
     CDS             complement(1344..1538)
                     /locus_tag="ACG84Z_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFP9162921.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1585..2433)
                     /locus_tag="ACG84Z_002112"
     CDS             complement(1585..2433)
                     /locus_tag="ACG84Z_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HFP9162922.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2638..2988)
                     /locus_tag="ACG84Z_002113"
     CDS             complement(2638..2988)
                     /locus_tag="ACG84Z_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162923.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3166..4029
                     /locus_tag="ACG84Z_002114"
     CDS             3166..4029
                     /locus_tag="ACG84Z_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9162924.1"
                     /translation="MFGLVQPNKVKVGQRIKEIKDGMSLSFTELGNRLGLKKPTISSY
                     VQGYALAPKSVINQLSSISGKPVGWFYFGHVEEYIREYLFLIGQKKIVDDYPEIIEKI
                     KQEFYTGEFKNPAWENELGYPLEEFIQECFVEYSSEIMKDYVVQITKEVLEESKTLNK
                     LSSKAKEEAVTILSSGIIDYIEMSGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSY
                     LIGKLINILGTDEDTELFLSSLSMIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREK
                     TPDEFYDWFEK"
     gene            4653..5645
                     /locus_tag="ACG84Z_002115"
     CDS             4653..5645
                     /locus_tag="ACG84Z_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162925.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5661..6545
                     /locus_tag="ACG84Z_002116"
     CDS             5661..6545
                     /locus_tag="ACG84Z_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162926.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6594..8201
                     /locus_tag="ACG84Z_002117"
     CDS             6594..8201
                     /locus_tag="ACG84Z_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9162927.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8202..9686
                     /locus_tag="ACG84Z_002118"
     CDS             8202..9686
                     /locus_tag="ACG84Z_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFP9162928.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9863..10855
                     /locus_tag="ACG84Z_002119"
     CDS             9863..10855
                     /locus_tag="ACG84Z_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9162929.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10907..11776
                     /locus_tag="ACG84Z_002120"
     CDS             10907..11776
                     /locus_tag="ACG84Z_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005472675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFP9162930.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12196..13809)
                     /gene="guaA"
                     /locus_tag="ACG84Z_002121"
     CDS             complement(12196..13809)
                     /gene="guaA"
                     /locus_tag="ACG84Z_002121"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFP9162931.1"
                     /translation="MRRTERAAYRTKFYSNLSSPTRFDEEPKIIVLDYGSQYNQLITR
                     RIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVL
                     GICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVT
                     QAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTG
                     DWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVL
                     LRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDE
                     ATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLF
                     KDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANA
                     GLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKI
                     SVRIVNEVAHVNRIVYDITSKPPATVEWE"
     gene            complement(13816..>14847)
                     /locus_tag="ACG84Z_002122"
     CDS             complement(13816..>14847)
                     /locus_tag="ACG84Z_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HFP9162932.1"
                     /translation="TRFLCHDCGRTFSAKTDLVDEHHQLTKELKQAILMELYENQSRK
                     LIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVLCMDEFKSMKSVSGSMSFICVDGT
                     THQLFTILEDRRLYKLTQYFLHFPRKARLKVKYLVMDMNASYCQLLKTVFPNAEIVTD
                     RFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYRRLKRYWKLLLKDSTTWEPLKRHY
                     HRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLP
                     QSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNFRARIY
                     LQQGLIFEN"
BASE COUNT         4525 a         2538 c         3076 g         4708 t
ORIGIN      
        1 aaaacgttga tttatcggca ttccccatcc atattatatt tacgtcttat tcccactcaa
       61 tatgagtagc ctcgtaaaga agctattata tcagtgcttt ttcagcctat tcctcatttt
      121 ggtagggaaa tggtagggtt agatttttac tgcttgattt ccattaaagt ttgcaacttt
      181 agattttgtt gcacaggtaa atttaatgtt tcctgtcatt tgttctgcaa ttccttcatc
      241 attacggctc catagatgag cgtagtgctt taaagtgatt tcagggctag aatggcctaa
      301 ccgttgcgac acgaccagaa tgtctgcgtt aaactcattg attaggtagc taacatgaga
      361 atgacgtaat ccttttcctt gtattagggg taccttagct agtttggcat aacgctgaat
      421 aattcgttga acagttgaac gatagagtgg gaggtcagtg tagctaagaa taaattgttc
      481 tacaccatga tttttttgaa taactttcca cttttttagc acttcaattg tatcatcgtc
      541 cagagaaatg atccgcaagc cgctttcagt ttttgtgtaa ggtttccgaa taaaatcttt
      601 ttgatttgtc atttccaagg tgtgatgaac cctcaacttt ttacgtttga agtccacgtc
      661 attccaatta agtgctaatc cttcgcttac acgaacacca gtcatgtaat atagccagat
      721 cattaaaaaa cacatatgtt cgtagaaatc atctttataa atttttgcca aaacttcttc
      781 aaattcttct tttgtccagt aaggaacgat tgattttcct tttggaattg cttttgttct
      841 tttggaaata ttctcattca gaaattgcag ggtgaccgca tagtctaatg atttacgaaa
      901 cataccgtac ataagtgaac tgtatgcttg tgagtatccg ctatcgttca ataaccaaat
      961 tcgataattt tcacaatctc gcacattgat ttcacgaagc ttcttatcac cgaaaaattc
     1021 agtaatctga atcaatccac actcacgaga actccaagta cttttttgta cgctagcttt
     1081 gtagtgtgga acgtaagact gctccataaa ttctttgtaa gttaaatcat aattcgcaaa
     1141 tccatttaca accatgtatt cattttttat acgcatgact tctttgtgtg cttcacgagc
     1201 tgatgagaat cgttttccta gagaatcttt tgttcctttc ttctggatcc tctttccagt
     1261 cacttgatct gttcctaact caactagata agaaaagcga ccatttttat cttgatacac
     1321 acaagggtat tttgttttca tagttattcc tcctgtgaaa gaggaacacc tataatttct
     1381 tcaattactt gtcggggtac taccccaact cttttattat tataatatgg atatccctga
     1441 tttaccattc ttgtttttgc ttgtcggatt attgtggtag cttgatgtgt tttaaatcct
     1501 agagcctcta aatcttttcg acaaattgta tttttcattg tataaactca ctttcaaaga
     1561 aaacactatc attgggtaat agtgttattt ctttattttt gtataatgaa cggtactttc
     1621 ttgaaaatcc atcacttgtt caggacttcc caactcattt aaagctaaag cattgtaaaa
     1681 aaatggacgt ctaactatat attcgcttgt atatagtata tcttgattcg tggaatcata
     1741 gggtttcttt accatctttt tggtgacagt tggtagtttg agattccggg acttgaaaaa
     1801 agcttttttc ttatgctctt tcaattccag ctctttatcg aaatatttgc tgatatagcg
     1861 cccgcgattt tcgatactgt ctacatcgat cttgttgatc ttaacgaaac cctgacccca
     1921 aatcgtagtt aaccggttaa atgagataaa ggggaaatca aacaagataa tatggtagtg
     1981 gattgcaccg cgttgctgct tttcccacgt ggcgagatac tttaaatttg cttttttagt
     2041 tttatagagg tcataattca gtcgtttgat aaatttttta aattcattat ttgcatactc
     2101 aatgtcttga atgttttctt tgaaagtgag agttaaaaat ttcgtttgat tgtcaaaatt
     2161 cgtgtctaca aggcgggcaa tctcaaatcg catactttga taatgtttct gtttgcgttt
     2221 taaactgtca tattgtcctt gagcggataa ttcatcatag ttttttcttt tttcaagagt
     2281 aatatcattt tcataaatcc aagctaattt ttgttttcgt tccagattta cttcgttttc
     2341 gatcgtttta cgtttgggag taatgattgc ttcataatca taaatttcaa tatacgtggg
     2401 agtttcaatg attttctgat tataagcttg caaaaatcat cactccttgt tgcgtattcg
     2461 attgtcaaag aaccagtcat tttctcctga tgttgatcta taaatcaagt taagggggaa
     2521 ggcctgcgta gcagcccttc tagcctatgg ggtgttgggc ggtcttaacg gacagaaacg
     2581 gctctgtggg cgctgccccg ccgtttcgtc ctaaccaccc aacactccat agtatagtta
     2641 gttttgtgta gtggtacctt gttttctggg aatcaaagtt gccgtatcag cggttgccga
     2701 taacccataa ctgacaaatt gtccattcga gcgtccccaa ggtacaatca ccaaattggt
     2761 aaatgtaatt atggctaaac cttgttgggt aagttcttcc ggcgtgatca caggatgttc
     2821 agatttgact ttgacactga ttttttcgta gcgaagtttt ggtaggatac attcgtagct
     2881 ccaacctaga atttcgccct ccttttgcca gcgagtgaca ttgacgactt ggtattcttt
     2941 ttcgagtgtt tcttttggta aactgagatc ggtaattttt attggcatca caattctcct
     3001 tttttatacg aaagtttata cgatttgatt aaaaaatata gatggccatc tacgacttgt
     3061 attatatacg agaacttata cgtagtcaag agattttcta aaaaaatata tacgattttt
     3121 tatacgagtg ttataatgaa aaaaatgata aggaggaatt tgaatatgtt tggtttagta
     3181 caacctaata aagtgaaggt gggccaacga atcaaagaaa taaaagacgg aatgtctctc
     3241 tcttttacag aattagggaa tcgattaggt ttaaaaaagc cgacgatcag ttcctacgtt
     3301 caaggctatg cgttggctcc taagagtgtg atcaaccaat tatctagtat cagcggaaaa
     3361 cctgtcggct ggttttattt tgggcatgtg gaagaatata tccgagagta tttgtttctc
     3421 attggtcaga aaaaaatagt ggacgattat cctgaaatca ttgagaaaat aaagcaagaa
     3481 ttttatacgg gcgagttcaa aaatcctgct tgggagaatg agctaggcta tcctttggag
     3541 gaatttatcc aagaatgttt tgtagaatat tcgagtgaaa tcatgaagga ctatgtcgta
     3601 cagattacga aagaggtact tgaagaatcc aaaacgctaa acaaactatc atcaaaagca
     3661 aaagaagaag ctgtcacgat tctttcatct gggatcattg actatatcga gatgagtggt
     3721 gagatcaagt atggagagaa agatcgcatt gcgaaaatgg tgaaagaatc aataaaaacc
     3781 tttgatgtga aacaagacct gacatttaat gattcctatt tgattggaaa gttgatcaat
     3841 attcttggta cagatgaaga tacggagctg tttctttctt ctttatcaat gatatttact
     3901 gataagcatt tttccactcg atttggtggg gaagaattag tcgaaatatt tcaatcgatg
     3961 cgaccagcgt taatcaaact ctatcgggag aaaacaccag atgaatttta tgattggttt
     4021 gagaagtaaa ataagaaaag tggcttagat tacaagttgg tgaaaaaatt tttttcagca
     4081 taacatcagt aatctataaa ggggttgttg attatactgt agaagttaag tactcaagag
     4141 attttttgta cgtaaacaaa gcaaaaaagg gtgcagtttc actagaaaat gtactctttt
     4201 ttgtgatttt tcttagttat agagtttttt tgaaacttta aaaatgagaa aacatattga
     4261 ttttaaagag tgtagacata gcttcttttg ctaaatagat taaacttact ggtgagtggt
     4321 cttgaacata cttttaaatc acattttact gagttttatt ggattttata attcattgga
     4381 aacctcgtac ttaatctgtt tttatctatc gactagaatc tgtatatatt ccagctatca
     4441 atgaggccgc agaaaagggt gcttaaaaat aatctgttgt ttaaaatatt attatcagaa
     4501 tacttagata caaaattctg gcacaaagta aaaaaaatat tgacttaaaa aaatggatat
     4561 ggtaatctat aaacgaaaat agtggtaacg tttccaaaat gcatcttcgt taaattttta
     4621 tttttttaaa cgaaaatgga aacgtttcta aaatgtattg ggaggagatt gaattggaaa
     4681 agacattggg accaggtggt gagataaggg cggtacaacg ggataaaaaa aatatttcga
     4741 agtgggaaaa attaaagaaa cagttgcggc gtgataagtg gatgtacttg ttgctcttac
     4801 caggtatcat catgacgttt atctttaagt atgtgccaat gtacggtgct gtgattgcat
     4861 ttaaagacta taatcctatg ctaggaattt tggaaagtcc ttgggtagga ctagatcact
     4921 ttagggaatt tatcagttca ccaaatttta cgcttttgct gagcaacaca ttaaaaatta
     4981 gtatttatgg tttattgtta ggtttttttc caccaattat tttagcactg agcttgaatc
     5041 aaattatcaa taaaaaaata aaacagaaaa tccagttgat tctatatgcg ccgaatttta
     5101 tctcagtagt tattattgtg gggatgctgt ttttgttcct atccgcaaat ggacctatta
     5161 atgggttagt agaaaaggtt acggggcaac caattatgtt catgtctaat ccagcttatt
     5221 tcagaacgat ttatatttta tcgggaattt ggcaaggaat cggctggtca tccattcttt
     5281 acaccgcaac gctggcggga gtcagtaccg atttatatga ggcagcaaat atcgatgggg
     5341 caaatatttt acaaaagatt tggcatatcg atttgcctgc attgaggcct gtgatggtga
     5401 tcagcttcat cttggccgcc ggcggtatta tgaatgtagg atatgaaaaa gcctacttga
     5461 tgcaaacttc aatgaacatc cctgcctcag aaatcatttc cacttatgta tacaaagtcg
     5521 gcttgcaatc aggtgattat gcctactctg ctgctgttgg tctgttcaat atgattatta
     5581 atgtcgtttt attactgatt gtcaacaata taaccaagcg gctaaacgat ggtcaaggct
     5641 tgtaatgaaa ggagaaaatt atgaatagtg ctttatcaaa aatcgaccgt caaatcttat
     5701 ggttgaatcg agtgattgta acttttttag tcgtcatcac cattgttccg ctgatttatg
     5761 tactggtagc ttcttttatg gacccagcta ctttgatcaa taaaggtata agcttcaatc
     5821 cgaaagattg gacaatacag ggatatcaac gggtatttgc agatgattcc attttacgcg
     5881 gttttgtaaa ttcgttgttt tactctttta gcttcagctt attgactgta tttattacga
     5941 tgatcactgc gtatcctttg tctcgaccta acttggcggg gaaaaagatt attatgactt
     6001 tttttgtcat tacaatgttc gtgggtggtg gcttgatacc tacctattta ttggtaaaga
     6061 acttgggcat gttagatagt gtatgggcga ttatcgtacc aggtgctata aatgtgtgga
     6121 atattatctt agcccgtacc tattttagtg ctttgccaaa agaactttct gaagctgcta
     6181 ctatcgatgg cgccaatgac ttgcaaatac tgttcaaagt catgcttcca ttagcgaaac
     6241 caattatgtt cgtattgttt ttatatgcct ttgttgggca atggaactca tactttgatg
     6301 ccatgattta catcaaagat cccgacttac agccgttgca actcgtatta agaaatattt
     6361 tgatccaaaa ccaaccttca caagacatgg tgggagccaa tactgccatg gcagaaatga
     6421 aacaaattgc tgagttgatc aaatacgcaa cgatcgtcat ttctagtctg ccattaatca
     6481 taatgtatcc tttcttccaa aaatattttg ataaaggtgt tttagttggt tctgttaaag
     6541 ggtaagtatt gttcactatt tgtatgaata aaaattataa aggagatttt aagatgaaag
     6601 caaaatggat gctgccaatc gtttttactt ccgtactaat tttgggggct tgtggaggct
     6661 caaaagaaaa gagtaaatca agccctgatt atgaactaga aaatgtctct tttccattga
     6721 aagaaaaagt atctttaaaa atgatgtctc aaagtgcccc tttggctccc aatgatccta
     6781 atgacaaatt gattttccaa cgattagaag aagagaccaa tctccatatt gattggacaa
     6841 actacagtag tgattttgcc gaaaaaagaa atttggatat cgctagtggt gatttaccag
     6901 atgccatctt caacgccgct gcaggtgact atgatttatt aaactgggcg gaaagtggcg
     6961 ttattgtacc gattgaagat ttgatcgaag attatatgcc aaatctgaag aaaatttttg
     7021 atgaaaaccc cgaataccga caaatgtcta ctgcacctga tggtcacatt tactctatgc
     7081 cttggattga agaattaggc gaaggaaaag agtcgattca tacagtaaat gggatggctt
     7141 ggatcaacaa ggagtggttg gataatttgg gtcttgaaat gccgcaaacc actgatcagt
     7201 tgatgactgt gttggaggct ttcaagacgc aagatccaaa tggtaatggt gaagcagatg
     7261 aaattccttt tagctttatt aacaatggag gaaacgaaga cttaaaattt ttaatggggg
     7321 cattcggtct aggtgataat gatgaccact tagtcgttga taacgatggt caggtacaat
     7381 ttactgctaa caaagaaggg tataaagaag ccatcaaata tttcaatgaa atgaataata
     7441 aaggtcttat tgataaagag gctttcgaac aagattggaa tacgtatgtt gccaaaggga
     7501 aagaacataa gtatggcgtg tactttactt gggataaagc aaatatcacg ggtgcagatg
     7561 atagttatga cgtcttgcca gtcttagcgg gaccagatgg aacgaaacat gttactcgta
     7621 cgaatggcat gggtttctca agagatcgtt tcgtaattac tagtgcgaat aaaaacttgg
     7681 aacttacagc taggtggata gataaaatgt atgaaccgtt acagtctgtc caaaataact
     7741 ggggaaccta cggtgatgaa gcacaggcga atatttttga attaaaggat ggtatgttaa
     7801 aacatttgcc tttagagggg acagcaccgg gggaactaag acaaaaaacc gaagctggag
     7861 gaccattagc agttcttgat tcttattacg gcacagtcac tactatgcca gatgatgcga
     7921 agtggcgttt agatttgatg catgacacgt atttgccata tattacagaa gacaatatct
     7981 atccacgtgt ctttttagaa aaagaagaaa cagatcgatt agcaaaaatc gaaacggata
     8041 tgtgggatta catctatcgc aaaagagcag agtggatcac cggcggtaaa atcgatgaag
     8101 aatgggaaga ataccttgct gaattggaac gtgtaggttt ggaagaatgg attcaaataa
     8161 aacaaactgg ctatgataat tttttgaagg gagcacaata agtgttagta gaagaaacgg
     8221 cgattttgga taaagcaaat cgatttattg aaatgatgcg aggaaaagtt aaccctcagt
     8281 atcgacaaaa ctatcatttt tccgcaccca tcgggtggat aaatgacccc aatgggttta
     8341 tatattacaa agggcattac catctcttct atcaatacta tccttacgat agtcgatggg
     8401 ggcccatgca ttgggggcat gcgcgcagta gtgatttggt ccattgggaa gatctaccag
     8461 tagcgttagc cccagatcaa ccttatgaca gcggcgggtg tttctcagga agtgcaattg
     8521 aaagagacgg aaaactatat ttattttata caggctgtca agaaattgat ggtattagcc
     8581 atcagcatca atgtttggcg gtctctgaag atggtattca ttttagcaaa tacagtggta
     8641 atcctgtggt agcagaaaaa cagctaggtg aaaatgggct aatacaagaa tttcgtgatc
     8701 ctaaagtaat tgttcacaac gatggttact atatggtagt agctactaaa tctacacagt
     8761 ctactggtag aatagtgatg tttcaatcgt cagatttgta tacttggcac ttttactctg
     8821 tgctgctaga agggacttca gagcaaggaa taatgtggga atgtcctgat ttattccatt
     8881 tagacggacg agatgtctta atcatgtctc cgatacaaat caagaagaac ggactggaat
     8941 atcataatat cagttctacc atggcttgta ttggtgaggt aaactgggaa acaggtcaga
     9001 tgatagttga taatttccat gaaatggatt ttggaatgga tttttatgca ccacaaacaa
     9061 caagagatcc taatggtgga cgggtgatga ttgcttggat gcagatgtgg gatcgtacat
     9121 tgcctacaca tgagttaggc catctttggg caggctctat gagtttgccc cgagagttaa
     9181 gagtgaaaaa aaatcgattg gtacaaaaac ccatctcaac tgtatatagt catttagttt
     9241 atcaacaagg cagtgaaaat attgcagtga ctgacacatc agtcgtattt cgaaacgcgc
     9301 tgtctgattc ttcatattta catctagtcg cagatttgga gaaagctgaa gtttttacaa
     9361 ttgaattact gcggtctaag acggattgtc tcaaactagc ctatgacact gctacacagg
     9421 tttttgaatt ggatcgtcag aaactaggaa gagagcttac aggggcggaa gaagaccctc
     9481 tgaatgtacg aaaagttgaa gtacctttga ttgataatca gctcgttctt gagattttta
     9541 gagatacctc atcaattgaa gtctttatta atgggttaga agttatgacg gctactttct
     9601 atgagctgga aaaagctcga gatatcttgt ttcattcgat cggagaaagt cgtattcaag
     9661 cttttgaaac agcgagtgtg aaataaatgt ttgattgctt aggcgatgaa tcaattattt
     9721 aataggtttt gaaggataat gtttttagaa aagaacagat agctagattt cccatggatt
     9781 tgctattagt attttgaaaa aattagtaat ttatgacaaa attcattata ctaaacttgt
     9841 gcagaaatgt gagggatcaa ctatgaaagc aacaatgaaa gatgtcgcaa aattagcagg
     9901 tgttggagta ggaactgttt cccgggtatt gaataacggt tctgttaaag cttctactag
     9961 agaaaaagtt gaagcagcaa tgacagagtt aaactatcaa ccagattttt atgcccgggg
    10021 gttaaagatg aagcatacga acacggttgc tttgattcta cccacggtat ggcatccatt
    10081 ttttggcgaa tttgcctacc atgtagaaac agcattagaa agacaaaact acaagcttta
    10141 tttgtgtaac tccagtggta atagtgaaaa agaacaagaa tatatccaga tggtcagcca
    10201 aaataaagta gacggcatca ttggaattac ttattcagat atcgatgaat acatttcgag
    10261 taatctgcct tttgttagta ttgaccgtta tttcactgaa gaggtgattt atgtgaccgc
    10321 tgacaatgcg gccggtggac gtttggctgc aaatgaactt tatcgccgag gatgtcagaa
    10381 tgtagcatat atcggtgggt accaagaaac accgaatgaa acgaagagtc gtcgaaaata
    10441 ttttgaaatc gagtgccgtc aactggggat ttcctataaa gcgttagata tgttagaacc
    10501 tttagaccat ctctcagaac gtgtaacaaa ttttttgtta gagaatcccg atatcgatgg
    10561 gatttttacg atcaacgatc caatggcatt agctgtcatt gatatgcttg aaaaaatagg
    10621 gaaaaacgta ccagaggatg tccaagttat cggatttgat ggtcaaaaga tgacagaagg
    10681 agatccttat ctagtctcaa cgattgccca acctacaaag caaatggcgg aagtggcagt
    10741 ggcaaaatta attgctgtca ttaatggaga gacagtagaa aaacgtaccg tattgccgat
    10801 tgaatttggc gaaggtgaca caacgaaacc tttagtgaga aacgattttg cttagtgcaa
    10861 atacgtttct ttttttgaaa atgagtgaat gaaaggtgta gataaaatgt tatatggtgg
    10921 aatagaagcc ggtggaacaa agtttgtctg tgggattggt aatgaacaat tacaagtgat
    10981 agaacggaaa agttttccta ccacaacacc agaagaaacg atggagcaag tgtttgattt
    11041 ctttgataag tacaaaggaa atatcgcatc aattggtgta ggagcatttg ggcctattga
    11101 tattcaaatc gaatcaagaa cttacggata tatcaccaac acaccgaagt tagcttggca
    11161 aaattatcat tttgtaggag ctttggaaaa cgccttgtcg gttcccatct attggactac
    11221 cgatgtaaat gctgcttgtt atggagaata tatggcaggg tatggaaaag gtaaaaatag
    11281 tgttctgtat tacaccgttg gtacaggtgt tggtggtggt gctgtagtgg atgggaaaat
    11341 agtcgcaggt tttagtcatc ctgaaatggg acatatgctc ttacaacgtc ataatgaaga
    11401 tcaatttgaa ggaatctgtc cttttcatca tgattgtttg gaagggttag catcaggacc
    11461 tgcgattgaa aaacgctttg gaagaaaagc ccagactatc tcatttgatc atccttattg
    11521 gacgattgag gcagattatc ttgctcagtg tgtgtataac acaacgttac tatatgcacc
    11581 ggaagtaata attttaggcg ggggtgtaat gaaacagccg caactactcg agttgattcg
    11641 ccaatcgttt aaagaaaaaa tgggttccta cgtggatacg cctactctcg aagaatatct
    11701 actaactcca aggcttgctg acaatgcggg cttgattggc tgcctagctt tagcaataaa
    11761 gaaactcaat cattagaata gtatttatta gaactattca taacataccg gaagtttaaa
    11821 agggtattct gaaacttaaa tagtctcaat tcattcttct ttcttgagaa tctgagtaga
    11881 gacttttatt ctgtttcaaa ttaatataat tacgaaatga tattgagtac aagaaagttc
    11941 tttttaccag atcttttaaa tcgaaaaatc tgatatatat atttatagta ctaaaaatct
    12001 gattagataa aaagctaatt caataggaaa ataaaggtag tgaataaaag caaagccctt
    12061 gttagtagtt aatctaacaa gggctttggt agggaaaatg gtaggaaacc atcttatttt
    12121 ttacgaaaat caggaacttt agtaattgaa taatgttgat ttataggtat tcctcatcca
    12181 tattatgttg gctctttatt cccactccac tgttgcaggt ggtttgctgg taatatcata
    12241 cacgatacgg ttaacgtgtg cgacttcatt tacgatacgg acactgattt tttgcaagac
    12301 ttcccaaggg atacgggcaa agtcagcggt catgccgtca atagaagtga cagcacggat
    12361 acctacagtg tagtcatacg tacggccatc tcccataacc ccaacagagc gaatgcctgg
    12421 taggacggtg aagtattgcc agatgtcgcg atctaaaccg gcattggcga tttcttcgcg
    12481 caagatagcg tctgattcac ggacgatttc taatttttct tctgtcaatt caccaaggac
    12541 acgaatacct aagcctggtc cagggaatgg ttggcgccaa acgatgctgt caggcatgcc
    12601 taattgggta cctaattcac gtacttcgtc tttgaacaat gtgttcaatg gctcgatcag
    12661 cttgaattgc atgtcttcag gtaatccacc tacattgtga tgtgatttga tggtttgggc
    12721 agtttcagtt cctgattcga tcacatcggt ataaagggtt ccttgtgcaa ggaaagaaac
    12781 gccttcttca ccggcaagtt tggttgcttc atcatcgaag acatatacaa attcatttcc
    12841 aatgatttta cgtttttctt ctggatcaga cacgccagca agttttgata agaaacgttc
    12901 tttggcatcg acttttataa tgttcaagcc aaattttccg ccaagacttt ccataacttg
    12961 ttctgcttca cctttacgca acaatacgtg atcaacgaag atacatgtta attgatcgcc
    13021 gatcgctttt tgtaaaagaa caccaacaac agaggaatct actccgcctg aaaggcctaa
    13081 taaaactttt ttgtcaccga cttgttcacg aatttttgcg atctccatgt cgatgaagtt
    13141 atccattgtc cagtcaccag tacattggca gacatctagt gtaaaatggc gcaacaagtc
    13201 atttccatat tcggaatggc gaacttctgc atggaattgg attccgtaca ttttgcgttc
    13261 tgcattttgg atcgatgcga tggggcaatc tttgctggta gcaacgacat cgaaatcagt
    13321 cggtgcttgg gtaactaggt caccatgact catccaaacg gtttgttttt caggagtgtt
    13381 ttggaaaagg gccgcttctg cagaagtgat ttccaattct gcttttccgt attcacggtt
    13441 tttggctggt ttaacttttc cgcctaattt ataagtaatc aactgcatac cgtaacagat
    13501 tcctaaaact gggatcccca aatcaaaaat cttttcatca ataccaaagg ccttctcatc
    13561 ataaacactg tttggtccgc cagaaaggat gattccttta gggttcattg cctttacttc
    13621 ttctgcggta atgcggtggc tcatcaactc tgagaaaaca ccgaactcac gaatacggcg
    13681 agtgatcagt tggttatact gactaccgta atcaagtacg ataatttttg gctcttcgtc
    13741 aaatcgtgtt ggtgaagaca aatttgaata aaacttagtc cgatatgcgg cgcgttctgt
    13801 gcgccgcata tttttttagt tttcaaagat cagaccttgt tgtaaataga tccgtgcccg
    13861 aaagttataa aagttgcgat aaccaaacgc aattcgttta atcagcttga tcttgttatt
    13921 cagcccctca gtgacgccgt ttgagtggga caccttaaag gcatttgaaa tacccgattg
    13981 gtagcaatgg aagatcgtga atttcttttt aaacgactga ggtaacgtag atgaaattgt
    14041 tttaagggtt tcttgaaagc cttccgtacc tcgtttaacg aaataatagc gtaataattg
    14101 acaaaaatga tacgcagttc gcaattcttc gttgtagctt aacagctcat caacgatttc
    14161 tgtttgacta attggtcgtt taaacagtcg atgataatgc cgtttgagtg gctcccatgt
    14221 cgtggaatct ttgagtaaga gtttccaata tcgcttgagc cgacggtact tcttctgatt
    14281 ttcagagtgt gaggttcgaa aacgattcat gatctggaca cgtaattgat tgaagctgcg
    14341 attgatgtgt tggacaatat gaaagcggtc agttacgatc tccgcatttg gaaagactgt
    14401 tttaagcaac tgacaatagc tggcattcat gtccatcact aggtacttga cctttaaacg
    14461 ggcttttcta ggaaagtgca ggaagtattg agttagtttg taaagtctgc gatcttcaag
    14521 gatcgtaaat agctgatggg ttgtcccatc aacacaaata aaactcatgg aaccagaaac
    14581 agacttcatt gatttgaact catccataca caacaccgtc ggaaggaagt tcatacgtga
    14641 ctggtaatgc ttcgttgctt cacgcaagat ccgtgtcacc gtcccatccg agacgaagta
    14701 cttcttagcg attagtttac gtgattgatt ttcgtacagt tccatgagaa ttgcctgctt
    14761 cagttccttt gttagttgat gatgttcatc aactaagtcc gttttcgcag aaaaggtcct
    14821 tccacaatca tggcagagaa aacgggt
//
LOCUS       DAZKCW010000057        14815 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000057 DAZKCW010000000
VERSION     DAZKCW010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.057"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(296..1024)
                     /locus_tag="ACG84Z_002123"
     CDS             complement(296..1024)
                     /locus_tag="ACG84Z_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162933.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="ACG84Z_002124"
     CDS             complement(1002..2576)
                     /locus_tag="ACG84Z_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFP9162934.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="ACG84Z_002125"
     CDS             2805..3743
                     /locus_tag="ACG84Z_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9162935.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="ACG84Z_002126"
     CDS             3755..4666
                     /locus_tag="ACG84Z_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9162936.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="ACG84Z_002127"
     CDS             4690..6162
                     /locus_tag="ACG84Z_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFP9162937.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="ACG84Z_002128"
     CDS             6213..6824
                     /locus_tag="ACG84Z_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFP9162938.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="ACG84Z_002129"
     CDS             6854..8767
                     /locus_tag="ACG84Z_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HFP9162939.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="ACG84Z_002130"
     CDS             8895..11876
                     /locus_tag="ACG84Z_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 TIM barrel-domain
                     containing protein"
                     /protein_id="HFP9162940.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="ACG84Z_002131"
     CDS             11873..13534
                     /locus_tag="ACG84Z_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein O-GlcNAcase"
                     /protein_id="HFP9162941.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="ACG84Z_002132"
     CDS             13574..14506
                     /locus_tag="ACG84Z_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HFP9162942.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4815 a         2333 c         2978 g         4689 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagt
//
LOCUS       DAZKCW010000058        13969 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000058 DAZKCW010000000
VERSION     DAZKCW010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.059"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(325..2322)
                     /gene="tkt"
                     /locus_tag="ACG84Z_002133"
     CDS             complement(325..2322)
                     /gene="tkt"
                     /locus_tag="ACG84Z_002133"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFP9162943.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2424..2675)
                     /locus_tag="ACG84Z_002134"
     CDS             complement(2424..2675)
                     /locus_tag="ACG84Z_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFP9162944.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2822..3445
                     /gene="lexA"
                     /locus_tag="ACG84Z_002135"
     CDS             2822..3445
                     /gene="lexA"
                     /locus_tag="ACG84Z_002135"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFP9162945.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3624..3842
                     /locus_tag="ACG84Z_002136"
     CDS             3624..3842
                     /locus_tag="ACG84Z_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162946.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4130..4642)
                     /locus_tag="ACG84Z_002137"
     CDS             complement(4130..4642)
                     /locus_tag="ACG84Z_002137"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFP9162947.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="ACG84Z_002138"
     CDS             complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="ACG84Z_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFP9162948.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLANEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7095..7538)
                     /locus_tag="ACG84Z_002139"
     CDS             complement(7095..7538)
                     /locus_tag="ACG84Z_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFP9162949.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7539..8327)
                     /locus_tag="ACG84Z_002140"
     CDS             complement(7539..8327)
                     /locus_tag="ACG84Z_002140"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFP9162950.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8324..9265)
                     /gene="rnz"
                     /locus_tag="ACG84Z_002141"
     CDS             complement(8324..9265)
                     /gene="rnz"
                     /locus_tag="ACG84Z_002141"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFP9162951.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9442..10029)
                     /locus_tag="ACG84Z_002142"
     CDS             complement(9442..10029)
                     /locus_tag="ACG84Z_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFP9162952.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10250..11563)
                     /gene="obgE"
                     /locus_tag="ACG84Z_002143"
     CDS             complement(10250..11563)
                     /gene="obgE"
                     /locus_tag="ACG84Z_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFP9162953.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11851..12861
                     /gene="gap"
                     /locus_tag="ACG84Z_002144"
     CDS             11851..12861
                     /gene="gap"
                     /locus_tag="ACG84Z_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFP9162954.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12946..13881)
                     /locus_tag="ACG84Z_002145"
     CDS             complement(12946..13881)
                     /locus_tag="ACG84Z_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9162955.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3856 a         3131 c         2454 g         4528 t
ORIGIN      
        1 gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgt cgggcactgc
       61 gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa taaaaagttc
      121 tcttcttaaa acaaacttaa ttaattaaat tatactttta attctcaaga aacacaaact
      181 aatccgaaga attctttgtt ttgtcattta aatgtaacat agccgaaaac gaaaagtaat
      241 attgatttat tcttctaaca cataaagaac agctgtctcc aacttgcaga cagctgttct
      301 tatcagtcaa acaattgctt ggatctatga tagttgattg tacgtattca cgacattttc
      361 tactgtaaat ccaaattctt ctaaaatttt agtgccaggg gcagatgcac cgaaatgatc
      421 gattgtaatc gttgcgccct ctgttcctac gtagcgttcc caaccaaatg atgcagcagc
      481 ttcgatagcc acacgtttct tcactgattt aggaagtaca ctttctttat attcagaaga
      541 ttgtttttca aagaggtcaa agcttggcat agaaacaaca gaaacatctt tgcctttttc
      601 agccaattct ttttgagctt tcacagccaa atcaacttca gaacctgttg caatcaaaat
      661 accttctggt gtttctcctt gtgatggaga aagaacatac gcgccttttt tcaccatttc
      721 atctgctact tcttttgtag aaggcaatac tggaaggttt tgacgactca atacaaggat
      781 agtaggcgca tctgttgtct ccatcgctac tttccaagca gcacgtgttt catttccgtc
      841 tgccggacga atcacttgaa caccaggcat gcagcgaaca gatgctagtt gttcaatcgg
      901 ttcgtgcgtt ggtccgtctt ctccgacagc aaccgagtca tgtgttaaga cgtaaacaac
      961 aggagtatgt tggattgctg ctaaacgaac tgctggtctt agataatcga caaagacaaa
     1021 gaatgttcca ccgtagatac gagttccgcc atgaagttgg ataccattca tagccgaagc
     1081 cattgcaaat tcgcggacac cgaaccagat gttgcgtcct tcataatgtt caggagtgaa
     1141 atctttatct gcagccacca ttgtattatt ggaacctgac aagtccgctg aaccacccca
     1201 gaagcttggt atagctttcg ataattcttg gatgacttct ttacttgaaa cacggcttgc
     1261 ttgactgctt ccaacttcat aagttggcaa ttctgcatcc cagttttctg gtagtttgcc
     1321 atcaaaagca tcttcaaatt gttgtgctaa ttcaggataa gcttttttat aattggcaaa
     1381 catttcattc catgcatctt cagctttttg tccttcttct atcatcgttt gatggaagcg
     1441 ggcagctact tcttctggaa cagtgaaatc tggatactcc caaccataaa cttctttagc
     1501 catcttgatg ccatcttcac caataggagc accatgaaca gcagatgttc cttctttagg
     1561 agcaccatag ccgatgactg tttttacttc gatcaatgtt ggtttgtctg tttcagcttt
     1621 tgcttcttca atcgctttag agattgcttc taggtcattt ccgtctttca ctaagatatg
     1681 ttgccagcca tatgcttcat agcgagcacc aacgttttct gtgaaagctt ttgaagttgg
     1741 accgtctagt gaaatatcgt ttgaatcgta taaaacgatc aatttcccta gtttcatatg
     1801 acctgccatc gaacttgctt cttgagatac cccttccatc aagtctccgt caccgcatat
     1861 tgcatacgta tagtgatcca tcacattaaa gttttctttg ttatacgttg ctgcaaggtg
     1921 cgcttctgcc attgccatac cgacagccat tgcaatccct tgtcctaatg gccctgtagt
     1981 ggcttctaca ccatctgtgt gatgtacttc aggatgtcct ggtgttttag aatcccattg
     2041 acggaattgt ttcaaatcat cgattgtcac ttgatagcca gctaaatgaa gcaagctata
     2101 caacattgct gacccatgtc ctgccgaaag aacgaaacgg tcgcggtcag cccagttttt
     2161 tgatgtcgtt ggatttactt tcaggtgttt tgtccataac gcatatgcca taggtgctgc
     2221 gcccatcggc aatccaggat gtcctgagtt tgctttttgg actgcttcaa tacttaatgt
     2281 acgaattgtg ttaacgccaa gttggtcaat tttgtcaaac aaaataaccc ctcctattaa
     2341 tttaggtttt ttttaccttt atttcttaca ctttcattct ataagatgtc acacgaaaaa
     2401 gcaatctttt tcagtatttt ttactaaaag ttgtcatttc ggttgtgtaa gccttttttc
     2461 ttttggattt cttttaattt ttccggggtc acgtcattgc cctcaggatc gacgactttc
     2521 attccttcga tatgatgacg cataccggaa cgaaaagctt ccaaatactc tttgcgtaag
     2581 ttgatttgtt cttgttcttc ggcttttgag agaccatttt ccttcttttt acgtgcaagt
     2641 tcattgatcc tctctatttt ttcaggtgac agcatgctca gccctccttt tactctcctt
     2701 catattatat aaaaactgaa aaaaaaacaa ctagataaac taaataaaat acgaacattc
     2761 gtttgattta gcgcttttta tatggtacta tttatttatc aagtgaaaga aggtgtacct
     2821 tgtggcccga caaactgaat caagacaaat cgaagtctta cgatatatcc atgaacaagt
     2881 aacccaaaaa ggatacccgc cgactgtccg tgaaatcggg gaagctgttc agctttcttc
     2941 tacttctact gttcacggtc atcttgcacg gcttgaaaaa aaagggttta tccaaagaga
     3001 tccgacgaaa cctcgtgcaa tcgagttgac aaaacaaggt ttagaaaaga ttgggattcg
     3061 tccaacaact attccagtac ttggcgtcgt aacagctgga gaacccattt tagcagtaga
     3121 ggatgcttca gacttctttc caatccctcc taatctttct tccgaagaag gcagtctctt
     3181 tatgctgaca attcgtggag atagtatgat caatgctggg atcttggatg gtgacaacgt
     3241 gatcgttcgg aagcaagaaa ctgctcaaaa tggcgatatt gtcattgcaa tgactgccga
     3301 ggacgaagcg acttgcaaac gattctataa agaaaaaaac tttttccgtc tgcagcctga
     3361 aaacgacttg ctcgaaccaa tcatcttaga tcaagtatct atattaggac gagtagtagg
     3421 actttatcgt agtcatatct attaattgct actaataaaa gaaaactttt taaaaagagt
     3481 ttgagacgat ggtctcaaac tcttttttcg cccgggttct tcttctttca aatttttatc
     3541 acttccctct ttacaaaccg aacaaatatt cgtatactaa atatacgaac aattgttcgc
     3601 ataaattaac gaggtgagaa ttcatgaaat caatgagacg tcttggctta gtattaactg
     3661 ttttgttttt aggtattatt attggtaatt tcggcatacg tccagcttta cttgtgtttg
     3721 ttccgttatt tactttgtgg ttcatgttgt gggatgaaaa gaagtaccgt caatctgagc
     3781 ggcgcagaat tcatgaagat catttctatc atgagcccta ctacagatcc aggcaatcat
     3841 aataaggatt gactgctaat tattcaaaag acaagaagtt aaacttttac gggggtgtga
     3901 caaaaatcgg tcacatcctt ttttcgaata aacggtgttc taaagccagt ttttcggtat
     3961 taagtcaaat tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat
     4021 ttataaaaaa atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt
     4081 taaaatcgct tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca
     4141 ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga
     4201 tcaaaaatgc gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt
     4261 tgattgttcc tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa
     4321 tggcatcctt atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga
     4381 tggtttctcg aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat
     4441 aagcaacagg acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc
     4501 gtttttcttt tgcataattt acgatttgct tcgtagcttc ccgataagcg tcaccatctg
     4561 ccatcagtgg ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg
     4621 caatataatc ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg
     4681 gtaggaatat cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgccgctgg
     4741 tataatctgc tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg
     4801 ttctctattg taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt
     4861 tcagggatac gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct
     4921 tgagaatgga tcagtttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa
     4981 taggcctcat caggcgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa
     5041 acttctttca gatccgctaa atcatctgga caatccataa taactagaga gttcggtttt
     5101 cttttttcaa ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg
     5161 ataatctcag gcacgaattt caacgtagaa gaatcaaatg ctaaataaag gctaccttcc
     5221 gacgttcggc tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc
     5281 acagaaaaat cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa
     5341 agctttccta ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca
     5401 aaagcgaccg catcaagctg actcgatgca ttggaaagga caaatttcag atgctgttgg
     5461 tttgctccga ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa
     5521 ggattatccg taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact
     5581 tcatttgcca gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga
     5641 tgatcgacta tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc
     5701 gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca
     5761 agcatttcaa aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct
     5821 tcttttaaag taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca
     5881 atgcccaaaa cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta
     5941 ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg
     6001 atctcattca atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac
     6061 gagacggcag gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa
     6121 aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc
     6181 tgaagtccta tccgttctga atgatgaatg gcattgattc ctaatgaaac aaggattcga
     6241 ttctcatcag tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat
     6301 tctacaggcg gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc
     6361 aaatctggaa atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct
     6421 ggtaaattct caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga
     6481 gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt
     6541 ccttcttcga tcttttcttg gtatacagat tggtttggtc catacccatg ctcaaatcga
     6601 tttggcagga atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt
     6661 gcactggtga tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt
     6721 acagcttctt ggattcggct gattgcttta tccatatcgt gcatcagata cggatcatgt
     6781 aattcttgtt cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt
     6841 tgccacagta acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag
     6901 gattcagaag gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca
     6961 ctcctaactt agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa
     7021 aaacagatca gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt
     7081 atgaaatatc cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt
     7141 tcttccggcg ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa
     7201 gcagcttcca actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct
     7261 tcaattttct tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt
     7321 tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc
     7381 agcgcagaac cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt
     7441 acaggaacat ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat
     7501 ccaagaatca cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg
     7561 ctggctaaat aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa
     7621 ataaacggtt gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc
     7681 aacttggcag gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca
     7741 gccttatcga agaaatctgt ctcgattgga cctggattca ctgtcgtaac agctacgcca
     7801 agtggtttca attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca
     7861 gaataaaccg ttgattttgc agttgccatt tttccagcca tagacgcgat attaatgata
     7921 tgaccttgtc ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct
     7981 aagatgttga cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg
     8041 aaaatcccaa aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc
     8101 ttttcatata attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc
     8161 tctttgccgc tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt
     8221 gcgcaactta taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga
     8281 ccgcctgaac tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct
     8341 cgcgaaatgg aatctcaatg ctatcaaaat ctttcatgat cgtcgtgttt tcaaacactt
     8401 cttgtgcttc tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag
     8461 taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg
     8521 aatggaaata gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca
     8581 gaatatcgct attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa
     8641 tagtcacgat tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc
     8701 catcttctag ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa
     8761 tacctaattc ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac
     8821 gataaccaaa actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat
     8881 cagtaaaaat cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg
     8941 tttgcgaaat acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct
     9001 ctaatggcgt atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa
     9061 tatgatcgcc gtgtaaatgt gtaataaaaa ttttaccgat ttttctcgga cgaatagtcg
     9121 ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct
     9181 cgtctaaaag tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac
     9241 ctgttcctaa aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt
     9301 ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa
     9361 cgttctaaag cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt
     9421 gagatcctct gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt
     9481 ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc
     9541 tttcgcatca tgcacatctt tttcgacatc ttcataatcc aagcgggtaa tttctccgcc
     9601 taattccatc attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat
     9661 cagtcctgta gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc
     9721 ttttatttct ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa
     9781 aatccctagc ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga
     9841 tttgttatta ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg
     9901 atcatggctg acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt
     9961 gatttctgaa aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg
    10021 tttgctcatt aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgta
    10081 aaataagaaa agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta
    10141 tcacagctcc tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct
    10201 cccttaaatc tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa
    10261 attcaaattc aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa
    10321 gagcttcatc cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat
    10381 gatcgaaatt cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg
    10441 catctgaatc acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag
    10501 tttcttcttc cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg
    10561 ctgtagcatt caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg
    10621 ggatgtcatc agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta
    10681 gattttccgg tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta
    10741 gcaagcgtaa gttataagta gataattctt tgttgatggc aagatagtct tcataaggat
    10801 ctcgtccttc catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat
    10861 gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca
    10921 agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttagggacga
    10981 gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag
    11041 tcgatttccc gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta
    11101 gttcgatttt tcgctcttgt cctggttcgc cgttttcagc aatttccggt gcaggattcc
    11161 gaggagaggc aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg
    11221 tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg
    11281 ttccttgtgg tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca
    11341 tcccattttc acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac
    11401 gtaacccttc atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg
    11461 gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc
    11521 cagctttcac atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt
    11581 attcatttat ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta
    11641 tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt
    11701 ttatcatttg gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa
    11761 tattctttgc gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac
    11821 agcaccccta ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt
    11881 gggcgtattg gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta
    11941 gtagcaatca acgacttaac aagtccaact atgttagcac aattattgca atttgactct
    12001 actcatggta cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc
    12061 gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac
    12121 ggtgtagata tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg
    12181 catttagatg ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc
    12241 atcgtctata acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt
    12301 tcatgtacaa caaactgttt agcacctatg gcttatttct taaataatga atttgggatc
    12361 gaagttggta caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga
    12421 cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat
    12481 tctactggtg ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa
    12541 ggacacgcac aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg
    12601 aaaacaaaag taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat
    12661 ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa
    12721 ggttcgatct ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt
    12781 aaaactgttg catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta
    12841 gaaaaattcg ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat
    12901 ccagtcaaag gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg
    12961 gcttaaaaat tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc
    13021 atgctcggct ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt
    13081 atctaacatt tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg
    13141 ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac
    13201 ttttgtcact agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc
    13261 tagctgataa gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt
    13321 cacattatct ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac
    13381 accgtataga acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg
    13441 tacatagtct ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg
    13501 tcctcttgca tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt
    13561 ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt
    13621 cgtttcagca ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca
    13681 atcgcttcgg ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg
    13741 tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt
    13801 ataaaaataa ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag
    13861 gattttcatc caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg
    13921 aattagtata atcaaagaat ctctactatg caatgttcat ttttataac
//
LOCUS       DAZKCW010000059        13873 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000059 DAZKCW010000000
VERSION     DAZKCW010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.060"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..176)
                     /locus_tag="ACG84Z_002146"
     CDS             complement(<1..176)
                     /locus_tag="ACG84Z_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFP9162956.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLA"
     gene            complement(655..1374)
                     /locus_tag="ACG84Z_002147"
     CDS             complement(655..1374)
                     /locus_tag="ACG84Z_002147"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFP9162957.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(1423..3069)
                     /locus_tag="ACG84Z_002148"
     CDS             complement(1423..3069)
                     /locus_tag="ACG84Z_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFP9162958.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            3248..3838
                     /locus_tag="ACG84Z_002149"
     CDS             3248..3838
                     /locus_tag="ACG84Z_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9162959.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            3930..5435
                     /locus_tag="ACG84Z_002150"
     CDS             3930..5435
                     /locus_tag="ACG84Z_002150"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFP9162960.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(5519..6871)
                     /gene="celB"
                     /locus_tag="ACG84Z_002151"
     CDS             complement(5519..6871)
                     /gene="celB"
                     /locus_tag="ACG84Z_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFP9162961.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(6871..7389)
                     /locus_tag="ACG84Z_002152"
     CDS             complement(6871..7389)
                     /locus_tag="ACG84Z_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162962.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(7405..7731)
                     /locus_tag="ACG84Z_002153"
     CDS             complement(7405..7731)
                     /locus_tag="ACG84Z_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFP9162963.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(7744..9723)
                     /locus_tag="ACG84Z_002154"
     CDS             complement(7744..9723)
                     /locus_tag="ACG84Z_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFP9162964.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(9744..10058)
                     /locus_tag="ACG84Z_002155"
     CDS             complement(9744..10058)
                     /locus_tag="ACG84Z_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFP9162965.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            10226..10519
                     /locus_tag="ACG84Z_002156"
     CDS             10226..10519
                     /locus_tag="ACG84Z_002156"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFP9162966.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(10597..11709)
                     /locus_tag="ACG84Z_002157"
     CDS             complement(10597..11709)
                     /locus_tag="ACG84Z_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFP9162967.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            11862..12710
                     /locus_tag="ACG84Z_002158"
                     /pseudo
     CDS             11862..12710
                     /locus_tag="ACG84Z_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13063..>13873)
                     /locus_tag="ACG84Z_002159"
     CDS             complement(13063..>13873)
                     /locus_tag="ACG84Z_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen binding domain-containing protein"
                     /protein_id="HFP9162968.1"
                     /translation="TGYELDATPIEFEIERSQTAVVELTKANRLTPGGVVLTKIDDQS
                     GEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATP
                     IEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVA
                     DSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT         4331 a         2832 c         2375 g         4335 t
ORIGIN      
        1 ctagccaaga acccatctgc tgaaatatga aaatttttga atgctacgac attcgccatt
       61 acaggtatgt aaaagaaaaa aatcatccaa agcatacccg gtacagccat caggacaagt
      121 gctttataac gccatagatt cataaaaaaa tgattgaacc cctttcgttt tttcatctaa
      181 aaaccccttt cgattcattc gcaacgtaat tatagcgctt tcaataatga gaataaataa
      241 acaaagtata gggaaaatga aacaaagtat aggagaggtt gtgaaatcag cgttttggcc
      301 tgagtattag agaaaaaaac gggaaaatag ttcctcatat tttgccgttt tttgagctaa
      361 taccgagggt cagctgattg aacaccgttt atcagaggtt gtgaattcag cgttttggcc
      421 tgagtattag ggagatcgtg tccttactat ctaactctga gtcacaagga acaatgggga
      481 ctgtaacaaa agtcttgtca cagtccctta ttccgaacaa acggtgttcc agaagtagct
      541 tctacggaaa taagccgaaa tttcacaaaa aagccatccg aaagtcagac ggacaagtct
      601 gcttttcaga tggcgctaca actactctgc ttattctttt agctatccat tcaattattt
      661 ttctctcact tgttctagct cttctttggt catgggtcga tattgccctt tattcaaatc
      721 tttaggcagc caaaattttc ccatacggat tctttttaaa tataagactt cttttcctac
      781 tgctttgacc attcgcttaa cttggtgaaa ctttccttca tgcaaaatca gacggataat
      841 tgaagtttct gtctcttgat ctacttgatc aatttggagt tttgccggca atgtctgctc
      901 atcgccatca ataatcagtc cttctgcaaa taaacggata tcttcttctg tcattatacc
      961 gctaacctca gctagatatt ctttctccac atgtttttta ggtgatagta actgatgggc
     1021 aaacaccccg tcattcgtta aaatcaagag gccctctgtg tctttatcta atcggccgac
     1081 tggaaaaaga tcttcccgat aatcctggtc ttccaataaa tcgattacgg tttgatcatg
     1141 attatcctga gtagcagaaa tgactcctgc aggtttatgc aaaatgtagt aaaaatcttt
     1201 ttgatacgta atgatttctc ctaaataagt aaccgcatct tcgaattcat ttacttgcgc
     1261 tttatcgctt ttcaccactt gtccattgac ttcgatcgtt ccttttttga tcaatccttt
     1321 gacttctttg cggctgccaa gtcccatatc tgctaaaaac ttatctaaac gcatgcgttt
     1381 cccccatttc aaaagagcat caatctagct cttctgattc acttatttta tttttaattt
     1441 atgtcgtaaa cgcgctattc ctggtcctag tagtctttct gccaagcgga ttttcaaagc
     1501 taaataacca tacactaaag cccctatacc tgctactaca agaatcaaca atagagactg
     1561 gaatttgcta tcttcgttta aaaaagcacc aaaaatcatc tttgtgatcc acgaagccaa
     1621 aagcataatc aaggtaagaa taaagatcag caatgtcctg cgccagacaa aacttggttt
     1681 aaagcgggct acttcatgga ttctctttaa gatcaaggta caagacacag caaatccgat
     1741 cattgtcgcc aataaagggc cgtatacttc aaataaacga atggctgggt attgaagaag
     1801 gagtttcact agaaacccaa taaccaaata attaattgcc gccttgtttt caaacattcc
     1861 ttgcagcatg ttggaaacta gcatatatag tcctaggaag agtcctacaa aacttgcttg
     1921 gatcagtaca ttacttccta gagaatccgg tgtataaaat aatgtattta gcggataggc
     1981 aagtaacata acaccaaatg tcgccggaaa cataaaaaat gaaaacaact gtaaatttcc
     2041 gcttgtcaat tttgccagac ctactcgatc tttcaacgta acagcttctg taatcaacgg
     2101 taacccagta gacgcgatcg atgttgccaa tgcaataact accatcgtca acttatctgg
     2161 attggcacta aaaatcgaaa aaagatccag taactgtgca ttggaatact cggtggatgc
     2221 agacatgatc ttcataaaag tgaactgatc gactaatttg aagatcgtta cccctgaacc
     2281 cacaataata aacggaatcg cttctttaac ggtatctaac aacaattcct tcgttgcaat
     2341 atttattttg ttttcgctgt agtgaataaa cgccgatgta tacgcttgat gtttcttcaa
     2401 aaaatacaaa aggacaagaa tacttgctag cataccgata aatgccgcga aagttgattg
     2461 cgtgaccgcc gtcacatagt caccatccat gactttcatg atgatgaatg tagccaatag
     2521 catataaaaa atacgtgcca cctgttctac aatctgcgac agcgcataag gcatcatttc
     2581 ttgattgcct tgaaaatacc ctcgtatcac actcatacaa ggaaaaacca atacagcgat
     2641 actcaaagaa cgcatcgttg gaatcagttc ttctccgcca ccagaagcat gagctagcca
     2701 aggagaggcg atgtacatga acaaagcaaa caacaggcct agcccgccca tcatctgtaa
     2761 tgcacggata aataatcgtc gtgaagtgcc atattcattc aatgaattat agcgtgcagt
     2821 ttgttttgca atcgcagcag gtattcctgc tgtagagatc agtagaaaca atgcatatat
     2881 attgtatccc atattgaata atccattggc agccttagca ttttcgccca tccaagcata
     2941 ccagggaatg atatagacag cgcctagcaa tcttgaaatg atattactgg cggtcatcca
     3001 agcagagcct cgtgccattt tttcttgcgg tgttaattga tctaatgctg gttttctttg
     3061 attatccatc ggtcagattc caactttcta caaaacatta ctatcatttt aattggtaaa
     3121 acagaaactg gcaatcgatt ttatataact tttataagaa caattgtttt tttgaattcg
     3181 gtttcgtttt tttggtaaag taaagaaata tacagccttt tatggctaac atttatagga
     3241 gatatcaatg acacaagaaa taaaaaaact acccgttata tttttaggtc ttttctttat
     3301 cacagttgga ttgaattggt tcttgctccc tcacgatata gcttccgccg gagtgggcgc
     3361 catcggacat ttagttgaaa cggccttttc tatccaacgc tcagttactg tttggagcat
     3421 caatcttatg atgctgcttc tagccgctgt cctattagga aaatcagtat tttttaagac
     3481 tgtagcggga agtctgcttt ttcctgttgt tttagagatt gttccaaaag tggaaatgat
     3541 ctcctcacat ttcttttcac tgatttcagg aagtcttttg ttcagtcttg gggtttacac
     3601 attgtacaca gtcggggcct caaatggcgg tataacgata ccgccgatta ttttccacaa
     3661 attttttcgg cttccaatgc cgcaaggact tttacttacc aatagtctta tcgtcttttt
     3721 gaattattat gtttttggat tgttggagac actattcgtt ctcctatcta ttacagtcag
     3781 ttcattgttt atgaaaatac tcatccgctt gtcccctgtg tcaagaaaat ttgaataaag
     3841 ctggattttg tcatagcgga aacaaacgat atattaaaaa gagtgtgcta taataaacca
     3901 agaaattgaa taaagcgagg gatcaatcaa tgagcttctc tttagaagac atccgtcatt
     3961 tactattaaa agaaaatcta ttaaaagaat ttgtttcaac aagaggctgg catcttgatg
     4021 taccagaaaa agctgaattt cttcagttaa gttatgattc aagaaaagct gatgcttcta
     4081 ctttgttttt ctgtaaagga atgaatttca aagaagaata tttggattca gcaatcgaac
     4141 agggtattca atattatgta tcagaacaac catacgaaaa ttcagcagta ggaatcatcg
     4201 taacggatat ccgtaaagca atggcgcttc ttgctatggc tttttacgac tatccgcaaa
     4261 ataaattgaa agtgatcgga ttcactggaa caaaaggtaa aacaactgct gcgtacttta
     4321 caaaagcaat cttggatcac acaacaaata aaaaaacagc attgctttct actatgaata
     4381 caacgttaga tggcaaaaca tatttcaaat cccatttgac aacgcctgag tcattagatt
     4441 tatatcgtat gatgtcagaa gcagttgaaa atggtatgac tcatctagtg atggaagttt
     4501 cttcacaagc ttacaaaaca caacgcgtat acggcttgac tttagatgtc ggaatcttct
     4561 tgaatatctc gcctgaccat atcagtccga tcgaacatcc gacatttgat gactatttct
     4621 attgcaagcg acaattgatc ttgaattcaa aaacagttgt tttaaatcat gaaagtgact
     4681 attttgattt acttagggaa acagccgatc tattccagat tccaacgatc acttatggtc
     4741 gttcggaaga aagcaattat caagtgatcc gttcagataa aggtactcac ggttttactt
     4801 tatcttctca tgaagatcgc ttagctatct gcgatactgc ttatgatatt ttgctggctg
     4861 gaggattcaa ccaagaaaat gcagccagtg cgatcattgc cgcagcacta acaggtgcct
     4921 ccagtcaaga tgcacaagac ggattaaaag aagctcgtgt accaggccga atggatcaat
     4981 tgatccaatc caatggagcg catgtctatg tggactatgc acataattat ctaagcttga
     5041 aaacattgct ggaatttgcc aaaaatgaac atccagatgg ccgtgtaatt gttgtattag
     5101 gcagcccagg aaacaaagca atctcccgtc gacatgattt tggaaaagtg ctatcagaaa
     5161 cagctgacat cgcctttttg acggcagatg acccagcatt tgaagatccg aaaaaaatcg
     5221 cggaagaaat caatgaagca attactaatc cagatttgat cgttcattat gaaatggatc
     5281 gtcctgaagc gattcgacgc gctttagcag aaagcgctcc gcaagattca gtcgttattg
     5341 cgggaaaagg cgtggatccc tatcaaaaaa tcaatggtgt agatgaacct tatgaagggg
     5401 attatgcaat cgtgaagcgg ttgattgaag aataatggta tttatatact agtggtttcc
     5461 catttctaag aaaaaaaggg actgtgattt tttgtcacag ttcctttttt cttagaaatc
     5521 attttaactt ttcactagct aattctgctg ccttttctct ttcttcattt aataatttat
     5581 tatcatagaa tttgataaat gggaaccaga taatgaatgc gatgattgca caaatgactg
     5641 ctaacacagc agctttccaa tcaccaccac taccaacaaa tgctccgatc ccgactggtg
     5701 aaggccacgg catctgtgca agcatcggtt tgacgatttc cagccgaatg gcaaaataag
     5761 cgagtgtagc agaagccatc ggagctaaga aaaacggaac cgctaaatag ggattgtaga
     5821 cgattggcat cccgaaaatg attggttcat tgatattgaa taatcctggt acaagtgagg
     5881 cttttcctaa cactttcagc tgatcagatt tcgcgaggaa tgcaataaag atgatcaatc
     5941 ctaaagtcgc acctgatcca ccaacggtta cataagaatt gttgaattct cctgccaacg
     6001 gataatttgc gccttgtgcg ttagctgcca tattagctaa tacgatcggg gtcaagaaag
     6061 aagtgatgat attcgctcca tggatcccta cgatccacaa tgcatggatc aagaaataaa
     6121 tcaccatgac accaagccat gtattcgtca actgcgtaac aaacccaaat gggatagcaa
     6181 tcattttgaa gatatccgtt cctagtgcaa ctaataatcc attgatgatc atcaccacaa
     6241 acgcaatgac aaatgttggg atcagagcag tgaaagaacg agaaactcct ggcggaacaa
     6301 catctggcat ttttatgacc caatttctct tgacacacat acaatacaat tcgaccgcaa
     6361 taatcgacat aataatagct gtaaagattc ctgaagttcc taaacgttcg acaaaagagc
     6421 ccatcctaat accatttact acagtttctg tctcattgat agaagcaatc aagctgattt
     6481 taccatcagt catgatcaat tcagggatac acataaagaa tgcaaaaaca gatagtaatg
     6541 cccccgtgag cggattaaca tttaattttt gttcatctcg ttcaattgac gttaattcat
     6601 aagcaaacac aatggcaaag taaatagata aaatccccat cgtcattgta ttgacgatca
     6661 tgtacaagtc actaactttg aaaaaagttg cattaaaaaa tccttctaaa aatgggaacg
     6721 gtaatggcaa aatatttaaa accaaaaaca tcgagcctac aatcgtgaaa ggaatagaag
     6781 ccatccccgc tgccatgaca gcccgaacga ttttaagttg cgcaattttc cccataggtc
     6841 ccatcaggta tttctgcaaa aaatcaaaca ttagttattc tcctttccta aatataacgc
     6901 tttttcatat tgtttaatac ggatatactg ttggtcttgg ttgagtgaaa ttttctttaa
     6961 acgatactgt ataaatgcac tggcaaaaat accgcttaca acaagaatga aaacaaataa
     7021 ctgtcctcca ttgttatttg ccataaaagg atacaagaat gtaaatcctg aggtaaacaa
     7081 cactggaatc actaataaat taaagacact ctggaacaaa aaataccact ttgtccatgg
     7141 aacgttcgtt tggtgttttc gataaagctt tacttgttct cctactgcag gcaaaatagc
     7201 taaaatcaga atcatcggta aactacttcc taaactttta gctgatagaa gcagaatcat
     7261 ccattgcatg ttcatgaaaa agaaaaaggc agtcaggtaa cgtacgatta gataacgatt
     7321 gaaatacatg tttttcaaac taagttgctt tttttctaat tcgattttcc tttttactgt
     7381 atcctgcaca atgatccttc ctttctattt atttttttga tacaaataat tcatttcctg
     7441 tgcaacttcc aataatgtca tcgtcgtcat cagatgatct tgtgcatgga ccatgataat
     7501 ttccatttct atttttgtcc cgctggcata ttctttcaga agttgagttt gtgactgatg
     7561 cgcatgaaga atctcttcat ttgcttgtcg caacttctct tctacttctt caaacatctc
     7621 tttacgcatc gagcgaaatg cttcatgtat cagtgtccgt gcatttccgc tatggaaaat
     7681 gatatcaaaa gaagtcactt gtagtgtttc actgtttatt ttttcagcca tctgttttcc
     7741 tccttattcg atcagtttga taaatttact gctgaaattc tcaaaaatag gttcagctaa
     7801 gatttcctgc tgtactttta gctggtcaac taacctaacg attgctttag tcacgaccgt
     7861 aattccttca ttttcgacat aagaaggcga aactaaaaaa acaaaatgaa tttcttgata
     7921 ttgatcccac tgcatcccag aaggaatcaa tgcaacggct acctttgttt cgattccaac
     7981 tggaacagcg ggatgtggga ctgccactgt atcactgaat atgatttgtc ccatattttc
     8041 acgttgctgg atctgctttc gcatttctct tatatatcct tcttcttcat ttatgctcag
     8101 cttttgcagc aaatcatgaa gaatttcttc ctttttcggt tcgtacgtat aagtcttgaa
     8161 aaatttttca gacaactgtt cggtgtaaat ctgctttttt tgctgtagag aaaatgctgg
     8221 tatcggtcta tctgaggaat gatagggtat agattctcca actacctttc gtattttacg
     8281 aacatcatct tcattcaaaa aaatactgac atgtaaaact ggaattttga aaaacattgt
     8341 cgaaagatca atagaagaaa taatcaggtc gattcctttt aaagttgttt cattgatctc
     8401 ataatagcct tttacactta ccactgtaat atttttaccg aattcactga ctacgcgatt
     8461 ctttaatagt tgggcactgc cgtaacccgt tgcacagata atcaatgcat gtagtttatg
     8521 cgcagctctt tctttttcca atgccgccat gagatgcaaa gccaaatagg cccattcatc
     8581 ttcattgatg gtatagtttt tcaaagccgg catgttgctg aaatgccttt ttactgcgtc
     8641 aaagactttg ggattttctt tctttatctc ctcagtcaat gggttctcaa tgcgaatacc
     8701 tcggctcaat cgaatcatca tcggtgacaa atgatcgagt agtccattga aaagctggag
     8761 atcctctact aatgaaaaat gaaattcctg agacaatctt ttcagaactt tcgctaattc
     8821 ctttgatagt tcctgatcat tttgattttc tttgtgattc gacttagcca tgagatgtaa
     8881 tgtcaaataa gcaatttctt cttcgggaaa cgatacacct gcgattacct caatacgttg
     8941 aacgatccgc tgcgccactt gatactctac tcgcttagaa acttcttgtt cgatgcctaa
     9001 ttccttgatt tcaaaccctt ctcggagccg tttgatcccc aaagccaagt gtaaagtcag
     9061 attctgtatg ataaaatccg aaacttttaa cttagcttct cttgtttcat cgagaatgat
     9121 aatgactagc tcttcaaaac tgatgtctgg gaaaaaacgg ctttgcccta aatattcttt
     9181 caatgaattt ccataatggt ttccaaaaaa agtatccatg ataaaatgcc gtcgatttct
     9241 ttcttcccct tcgatccatg tcccttgacc atgcttagaa acgattttta gtgaatatgg
     9301 aatcaatcgc tccttgattt cttgcatgtc ctttgtcaaa ctggaacgac tgatataaag
     9361 ctcttctgcc aaatcatcca taaaaagaat ggcatcttcc aaaagcaatt ggttcaatat
     9421 atacttttgt cgatcttcgg actcataaaa tccttgcggt tctctagcat atccaggtac
     9481 tatttcttgc cgactcaaaa acaagtcaaa tgtcagtctt tgtaaaatat gcagttggta
     9541 gccataacct ggtttagcaa tgatcttacc tccgtttttt tctactaact ctttgatccg
     9601 ctgcaagtaa ttacggattg tccgatcaga taataacaat tcagaagcta aacgttgact
     9661 ggtgacatac tccttcttgt gatcaatcaa atatctcaac agcaattttt ccttctgttt
     9721 cattatcatc cactcctatt ccatcatatg ttctcttcga tcacctctgc taacttctgg
     9781 atgcctgtag ggattgggac atacgcttgg aaagggatac taacaacagg ctttccaaca
     9841 gattctccta attttttgaa tttatccaaa aacatcgtcg tttgcgggct gatcagaaat
     9901 aaatcaaaat cactattctt aatcatatta tcgccttctg tagctgaaac tgcatctacg
     9961 agtacctctt ctcttttttg cttaaagaaa tccgttgtct ttgaggccat catcgaggat
    10021 gacattcctg ccgcacaaat aatcaatgct tttttcataa atcaatcact ccttttattt
    10081 ttataaacca agcatatctt gtaagcgttt tctattcaaa atatatattt ccgtagcatt
    10141 gcggaaaaaa tgtgtatcat atcttgaata ataatttctg gcaccgtgat atactagtga
    10201 tagaattttt tcaggagggg atttagtgag tatcacagtg aatattttgt atacaagtac
    10261 aaatggacaa gccagaaaat ttgcagaaga aatggtcgaa agaaacattg tcaaagcgat
    10321 tcgtgcagaa gaaggaaacg agaaatatga ctattacttt ccactagaag atccagaatc
    10381 tcttttactg atcgaccgtt ggaaagatga agaagcaatc gaaaagcatc acaaatccga
    10441 aatgatggct caaataaacg aactccgtaa aaagtataaa ttaaaaatga aagtcgaacg
    10501 tttcactgat ttaccgtaaa aagatacaca tggaatgata gcaatttatc atccatgtgt
    10561 atcttcactt tttccttatt ttttattcga tctcatctaa tgattcaaac cgtgtttttc
    10621 tcttattttt cggataagta tttcagtcac cccaatatac atgattccta aacatacccc
    10681 aaggatattc tcaaaaatgc ggatcgttac tgctcctgga accccgaata aactggcagt
    10741 gattgccaaa gcaccaaaag aattaaaaac tgttttatat ctataggtag aacaaacacc
    10801 taaagctaga ccacctaata taccgaccca gttaaaagga ataaattggc tgataccaat
    10861 aaataaaaca catccaatca atgagccaat gattcggtct actgctcgtt ctttgaaacc
    10921 aatcgacatc aatccatagc tagatacaat agaagaaaat gcaaaccctg cccacatcaa
    10981 tcgctgaaaa gggacatact ctcctgcaac gatcaaaaga ctaatgccaa atgcatagat
    11041 gagcatccaa attttttcct gcgaatacat gcctttcaaa aaaatctctt taaacaagct
    11101 tttgtctttg ttcttttctc gatgttttct gtaaagaaga actgaaaacc aacaaaaaaa
    11161 caaaaataat aagctacttg tttgtgtaaa gaaattcttg ttcaacgaat ctttaggtaa
    11221 cgaataaaca ataaagagat atgaaaagcc gtacaaagaa gcattcccca ttttgggatc
    11281 actagcggtt gccattaata tgctgcttag taaaataaaa tgaatcaaca tgcccataac
    11341 tgaccatttg atcagctgga catacggtgc tactaatagt gagaacatga cgattgctaa
    11401 acctatgatc gaatgggaaa tcttataacc aaagtcaaca aaacgaatac tcatcaacat
    11461 acagaataaa accacagcgt atggtttatg cttcgattca aataatgttg taattataat
    11521 gataaaacaa atggcaaaca atacgatgaa taatgatcgt aaaaacaatg aacaaatata
    11581 catgcacttt tcttttttag aagctgcttc tcgtattttt tgttttaaaa taaacggatc
    11641 tagttgtaga gactgataaa aatccacctg ttgtcgtcct ttctttttac ttttattttt
    11701 tacagtcatc tatgacaggt tgtaaatact atggaacatc atatggcgtt gtcattttct
    11761 tgtcaactat ttttcctatt catgttttta taaaaaaaca tatcgttttc ttgtatgatt
    11821 aaatcaccac aaaataaaca actgagagaa cgatatgctt tatgaatggt tctatcaaaa
    11881 aaattctgag atcaatagac aaaaatttga tgattacaga ggtctcttac gaaaccttac
    11941 agaagaaaaa aacattgatc gttgctgcag ttctcttccc tgctccatgt gtctgtagaa
    12001 attgtggttc tgctgtggta gatggaaata ggaaattaat ggtggtgaaa aacaagaaga
    12061 aggaaaccat tgtccacttt gaataatata atcatatgcc aatggttata cgcctaaaaa
    12121 agcagcgcta tacctgtaaa aactgtcgaa gccattggaa cgctcaaagt tattttatcc
    12181 gtccaaggca ctcgatttca aatcatgtca gacataaaat cacttcttta ctgactgaaa
    12241 aagtgtcgtt attttttatt tcgaaaagtt gttaggtatc tttgacaacc gttattcgca
    12301 cattgaaaga gttgagaagc tatttaccaa agtcttccaa aagaattctg tcttgagtgt
    12361 tgagggttgt gaatttcgtt ctcacgtttc cgttgaggat aaactgagtt ttatttccgc
    12421 ggatggcgag acagaaaaat taatcgagaa aatttaccta cacaaaaaat tcctcgatta
    12481 acaaactatt tccttagctg cactaatcct aaagaaatag aattcttagt tacagacatg
    12541 aacgccacct actttcagct caccaaacat gttctaccaa atgcgaaatt ggtgattgat
    12601 cgattacttg gtttttccac gcctttcaag gaggcgtaac ctttattcac gagttggttg
    12661 aagctttccg agacaaaaga cccgacttgt ttttctcctt attgacaaag agccattaaa
    12721 actagagaaa aaattacaac tgatcgctga ttatttgtag aaagaaaatc aaagtattac
    12781 ccaataaact tgagtcatta ggcaaaaaac actgcgaaac tcaagaatga ttttcgcagt
    12841 gtttttgtat attttttatt aactagtatt actacaaagg tttatttttc acttctcaac
    12901 gcagcacaaa attgtcttta cttatttact ggttgggttc aaccttctct actccgatac
    12961 taatatttgt ttgtataccc cttctaaaat cggtagtttc cattcaattg atgggtacta
    13021 gttgatttta aaaactatgc ttattcaatt ttttatttta gctcatatat ttcgtttctt
    13081 tctaaatttt atactgatga aaacaagtag cacacccaat attgacaata taaactggct
    13141 aatgatggtt tctccagttt ttggaagatg cttatttcca ctgcttgttg gattgtttcc
    13201 tcttatatct gagctatcag caacttttct attctctttt gttaaaaaga tcgccacttc
    13261 ttgttctttt tcgatcttga aagttactgg tgtcgcatcc aattcatacc ccgttggcgc
    13321 ttgagtttct accagctgat atgctcctgg tgctaagcca tctatcgcca gttttccatc
    13381 tgctcctgtg gttagacctg actgcagaac ggttccattg gcatcttgta actcaaaaac
    13441 agctccttgc aggacttctc cgctttggtc atcgatcttt gtcaacacga caccgcctgg
    13501 tgtaagtcga ttttctttcg tcaattctac caccgctgtc tgacttcttt cgatctcaaa
    13561 ctcgattggt gtcgcatcca attcataccc cgttggcgct tgggtttcta ccagctgata
    13621 cactcctggt gctaagccgt caatcgccag ttttccatct gctcctgtgg ttagacctga
    13681 ctgcagaacg gttccattgg catcttgtaa ctcaaaaaca gctccttgca ggacttcccc
    13741 gctttggtca tcgatctttg tcaacacgac accgcctggt gtaagtcggt ttgctttcgt
    13801 caattctacc accgctgtct gacttctttc gatctcaaac tcgatcggtg tcgcatctaa
    13861 ttcatacccc gtt
//
LOCUS       DAZKCW010000060        13747 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000060 DAZKCW010000000
VERSION     DAZKCW010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.061"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            62..256
                     /locus_tag="ACG84Z_002160"
     CDS             62..256
                     /locus_tag="ACG84Z_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162969.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            525..824
                     /locus_tag="ACG84Z_002161"
     CDS             525..824
                     /locus_tag="ACG84Z_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162970.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(921..1355)
                     /locus_tag="ACG84Z_002162"
     CDS             complement(921..1355)
                     /locus_tag="ACG84Z_002162"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9162971.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1587..2297)
                     /locus_tag="ACG84Z_002163"
     CDS             complement(1587..2297)
                     /locus_tag="ACG84Z_002163"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFP9162972.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2287..3147)
                     /locus_tag="ACG84Z_002164"
     CDS             complement(2287..3147)
                     /locus_tag="ACG84Z_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFP9162973.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3152..3790)
                     /locus_tag="ACG84Z_002165"
     CDS             complement(3152..3790)
                     /locus_tag="ACG84Z_002165"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFP9162974.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3805..4104)
                     /locus_tag="ACG84Z_002166"
     CDS             complement(3805..4104)
                     /locus_tag="ACG84Z_002166"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9162975.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            complement(4147..5631)
                     /locus_tag="ACG84Z_002167"
     CDS             complement(4147..5631)
                     /locus_tag="ACG84Z_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFP9162976.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            complement(5651..6112)
                     /locus_tag="ACG84Z_002168"
     CDS             complement(5651..6112)
                     /locus_tag="ACG84Z_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9162977.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6130..7197)
                     /gene="ulaG"
                     /locus_tag="ACG84Z_002169"
     CDS             complement(6130..7197)
                     /gene="ulaG"
                     /locus_tag="ACG84Z_002169"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFP9162978.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7415..8185
                     /locus_tag="ACG84Z_002170"
     CDS             7415..8185
                     /locus_tag="ACG84Z_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFP9162979.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8458..9285)
                     /locus_tag="ACG84Z_002171"
     CDS             complement(8458..9285)
                     /locus_tag="ACG84Z_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9162980.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9852..11087
                     /locus_tag="ACG84Z_002172"
     CDS             9852..11087
                     /locus_tag="ACG84Z_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9162981.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12086..12346)
                     /locus_tag="ACG84Z_002173"
     CDS             complement(12086..12346)
                     /locus_tag="ACG84Z_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFP9162982.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12373..13674)
                     /locus_tag="ACG84Z_002174"
     CDS             complement(12373..13674)
                     /locus_tag="ACG84Z_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9162983.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
BASE COUNT         4414 a         2822 c         2173 g         4338 t
ORIGIN      
        1 atcattttca cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca
       61 aatgtattat gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat
      121 cagtaacgaa tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg
      181 tgccataaaa ataaagaacg agctagaaaa agaactgact tgtggcaaag ctgttgtaga
      241 tatcatcgaa aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac
      301 aaattgctaa gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat
      361 aaatgtttgt ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga
      421 gctatatcaa gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa
      481 attgtttatt tttataatgt atcagtatag aaaggaaata aaacatggat tatactgttg
      541 aatttgacag tgaactactt aagcaatttc cacaagaaga acatttcatg tataaagaag
      601 caatttccca caaagtgaca gagtatttgg agcataattt ttttcgtata aagccagtgc
      661 gtactcgttc ggcaaaagga atatacgaga tgaaagtcaa aattaataaa aaaaattatc
      721 gcatagcatt tgctttaaaa aaaaatcatg tgttcatttt ttatattagt tcgaatttgc
      781 aaaaaattgt atttgataaa gaggtgagta aaaaaataaa atagctgagc attggaggat
      841 agattgagtg atactaagtc tatcctcttg tttttctaaa gaactaagct agaatttttt
      901 cttttgtacg ttattatatg ttatttgtca ttaccaaaaa gcaccttttt tcttctagta
      961 tctatgacat aagaaatacc acccatttcc tttacttgaa caaatcctac tgattcataa
     1021 aatttttttg ttttctcagt atcatctgtc aataattcga tttggactgg tccataacta
     1081 gtgatcttct ccaaagcttc attcaaaagc actttgccta ttccttggcg ctgatacctc
     1141 ggatgaatga ggatatcttg aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg
     1201 attccgataa tcttcccttc cccattacgc tttatcagag attcagattg ttcaaatgct
     1261 ctagctaacc ttgcagtgtc ttttgtgtaa ttcgtccaac caacgctctt atataattca
     1321 gaaatctcat cgatcataag ggaatcaata ttcatttttt tcttcctttc ttatacaatt
     1381 ctccctctaa taatacagtt ctttgactat ttaatctatc acatataact ctcctgtaaa
     1441 gattctctcg attccttaaa atctctcttt ccttttagaa tgcatccttt ttgataaata
     1501 aaaaggttgt gataaatttt cttcacaacc tctgtttctc tctatcaagt gttatctttt
     1561 aattttctac ccttacccta gcatctctat tgcccgtagt atgcatactt tccatgtttg
     1621 cgaaaataat gtttatctag taaatattgc gggatttcac atatattggg gttgatcagc
     1681 tcgttttctt tggccatcag acaaatttca tctaagatca aactgttttc tactgctttc
     1741 ataggtgaat ccccccatgt gaacggtcca tgtccataga caagtactcc agggacttcg
     1801 tttggatcta attttctttc cttaaacgtc tcgacaatca cattccctgt atgaacttcg
     1861 taagcttctc ttacttcttc tttcgttaat tggcgtgtac aaggaacctt accataaaaa
     1921 gcatcagcat gagtcgtgcc ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg
     1981 gagtgcgtgg aatgagtatg agtaatagca gttatatctt caaaagtttg atacaaaaca
     2041 acatgtgtgg ggagatctga agatggtttt aagctatctt cttctattat atttcccgac
     2101 aaatctgtta ccaccatttg atctgcttgc atgcattcat atctgacacc gcttggctta
     2161 atgacgatga ctcctagctc acggtccact tcactcacat tgccccaagt caatttgact
     2221 aatccgtatc gcggcaatgc cagatttgct tcaaggacac gttgcttcat tgctgcaatt
     2281 ttttcttcac aagacatcat agccagcctc cttcaattta gaacttaagt agtcttttgc
     2341 ctgctggatt tctcttcgaa agtcttggct tttttcactc cacatttcaa tcagaaatgt
     2401 tccatcataa tctagacgtt tcaaatgtct taataatcca agaaaatcaa cacaaccgct
     2461 accaaaagga acatcacgaa actggcctga atattctttt gttacagggt aagtatcttt
     2521 taagtggata gcagtgatat aatcgatccc tttctcaagt tctcgagccg gattattttc
     2581 cggccatgcg gacaaattgc ctaggtctgg atatacttgt agaaaagggg aatgaatctg
     2641 ttctttgatt tctaaaaatt ttgaaatgga gttcataaat ggatcatcca tgatttccac
     2701 ggaaagaatg atgccatatt tagaagcttc ctttacgctt tcttttattc cttcgataaa
     2761 gtcttctctg gaattcattg atttctcttc ataataaaca tcgtatccag ctatttggat
     2821 tactttgacg cttagattat gcgccaaatg gattgctttt ttcattagtt gtttcgctgc
     2881 ttttttcttt tctggatcag cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat
     2941 cgaatggata cgtacaccgg agctgaacat ctcttctctc agctcagcta tcttttcttc
     3001 agaccaatct aatcgtgcta accgctcatc cgtctcatca atcgacatct cgataaaatc
     3061 gaagtccatt tcttttacaa gggaaaaacg ttctttccat gaaatatctt tgggtaatgc
     3121 tttttcataa atcccaattt gagccatttc cttaccccca gatacgaatg atctcatctt
     3181 tgaagttttg tgcggccttc atcggatcat ttgctgctgt aataccacga ccagtgataa
     3241 aggtatacac atcgatccct tcaaataagt gtaatgtgtg tggatttaat ccaccagtta
     3301 cagaaacatt aaagcctagt tcaatcagtt ttttgatctt cgataaatct ttttcacccc
     3361 aagtttcacc agataacagc gcatcacggc tttgatggta gattacctgc cggataccga
     3421 tgttatgcca atccatggct tgttcaaaag tccaattgcc gtagagttct acttgcaatt
     3481 cacctatttc tttttgtgct gcctccatag ttggaatcgt tgcacaacaa atgactgtca
     3541 tccagtctgc tcctgctttt gcaacattac tcgccactgt tcctccagcg tctgcacatt
     3601 tcgtatcagc gactagtttt ttatctggga acatactgcg aatacagcga atcgcttttt
     3661 gtccttcctg taagcaaaga attgtgccca cttcaataat atctactaca tcaccaactt
     3721 tcataacatc tcctaatgca tgttctaagt cattgtgatc taacgcaatt tgcaaattcg
     3781 gcctgctcat cttagttcct tcctttactt gtttttttgg taccactttg tttcagcaaa
     3841 tttttcactg atttctttgg ctgacatcac atttttgata ccgataactg taacttcttt
     3901 tttctctgcc tgagtaaaca tattcaaaaa attgactggc gtaaaaacta catcgtattg
     3961 gccagctgaa ctttttccct ctgaaatggc acaatgatgg attttggtaa ttggtacgtt
     4021 tagttctttc attgcttttt ccacacttct catcatcatc aagcttgttc ctgatccatt
     4081 tgcacacgat actaaaattc tcatcttaat ccctccatta tgagtgttgt ctaatcagat
     4141 tttcttttat actctctgct tttctgcata tgtgtcatag tcttctacaa tcaaaaaata
     4201 accctcagga tttttccgat attgtaactg cggaatagcc aataaaccaa tgacaactac
     4261 ggcaattcca gcataaccta ggactttcat gattactgta aacaatggcc aagctgttgc
     4321 ccagtcgaac atcccgatat aaccaccata tgttgacatc ccaatccatg tagcgaataa
     4381 tgctgaaccg cctacttgta tgattcctga aagaaacggg aacaggcaag cggctttgaa
     4441 tccacctcgg ttattggcat aaactgctat aacggcatta tcaaagaaca acggaatgaa
     4501 accggctatg acgatcgttg gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg
     4561 tcccaaagca ccaaacaaga acccaatcgt taccgcattt ggcgaaccaa agccaaaagt
     4621 agcagctacg tcaattcctg gaacagctcc tggtaaaatt gtgtttgaga ttccttggaa
     4681 agattgagtt agttcatcga cgaatgtccg aacacctaat tgcaagatcg ccagatatac
     4741 cgcaaaattt aaagaagtcg tcataatgta gaataagaaa ctctgtcctt cttgcatgaa
     4801 ttgcgcttga atcaaataat ctttgcctag tacaatcaga atgatcccaa agaaaaatag
     4861 catgagtaac gaagtagcaa ccatattctc attgaaaatc gacaagaatc ctggtaattt
     4921 gatatcttcg atttttttgt cttgcttgat tgatctattt ttcttttcat cccgcttttt
     4981 catccactca gctaattttg caaatataaa gattccgaac atttgctgat gtgccactgc
     5041 aaatccggca ccttctgtca attcctgcgt gattcctact gttaagttag aagctactgc
     5101 ccaataacaa cctaaaatca gtcccataaa aatcaatact tgtatcctac ctagatcagg
     5161 aaagcaaaac agtaaaatcc aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt
     5221 agtgaaaacg gaacgcagtt tcgtatattt ctgaaaacgg actaataaga tatttaaaac
     5281 aaatgcaatc agtaataaaa tcatcacatc tccaaaggta cggccaaatg tctccattaa
     5341 tccagcatcc acagcatttt gtccaaaata aggatctgta accatggcat ccaaattgaa
     5401 ccgttccttt agtccaacca aaatcggccg aaaattattg accaaaccac cagagccaac
     5461 agtcaaaata aagtaaccga ccgttgcctt taagaatcca gcgatgcatt catgaagcgg
     5521 gcgtttcagc aaaatatagc ctaataacac gataaaacca atcaggtatg ctggctgcgt
     5581 caagatattt gttgcaaaat acgtccaaat gcttaacaaa aattccccca tcttttttct
     5641 cctctatcaa ttaattatat tctgccatca caacttggta atcatcgatg gagttcgtag
     5701 agatgagacg ctcaaccaat ccatctgtca ttaataattc ggataatttt tggatatttt
     5761 ctagatgttc ttctggatct tttgctgcaa gtgtaaaaaa caaactagcc gttttctcct
     5821 catcctcccc ttcactttca aaacggattg gctgtttcaa cttggtaaat gaaatagctg
     5881 ttccaaaaac accatcactt ttttctgaag aatgcggcat tgctacttga ggtgcgatca
     5941 caatataagg accgtatttt tctacacaat ggatgatctc ctccacatac gtttcatcaa
     6001 taatttcctt atcgatcaat acaagacagc tttcggcgat agcttcacgc caatccgtga
     6061 tttctttatc tgggtaatga atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc
     6121 ccttctttct tataaaaacg acggaaacgg tgtatcattt tcaatcgaga agacatcttc
     6181 aaatcctcga taaaaattaa actcaagatc atctttgttt gtcggataga tgaatttccc
     6241 gcctacttgc cagatataag gtttaaatcc atacttcagg cgatcctttt tgaatttcca
     6301 aatttcagtg atctcttttg aatcagccat aaaattagac caaatatcgt agtggacagg
     6361 aatcactact tttgcattca atgactccgc catgcgcagc atatcaacag aagtaacttt
     6421 gtctgttatc cctcgtgggt tttcaccata ggcccctaaa cagacatcga ttttgtgttc
     6481 attaccatgt ttggcaaata aattggagta atgtgaatct cctgcatgat aaagattccc
     6541 tcctgatgtt tcgaataaat agtttactgc aatttgatcc atctcctgag gcatttttcc
     6601 ttttaatacc tcttctggat cttcacaagt gaccaacgct gtccgatcaa acgcttctaa
     6661 agctactaca ttgatgtctt tgattttgac tgcatcacct ggctttactg taatcgtttt
     6721 ttcttcagga attccccatt tttgccacgt gcgaaccact tcttttggcc caatgaatgt
     6781 tgcttcagga caattttgat gaactgctgc ggctgtatgg atatctagat gatcggaatg
     6841 gatatgtgta acgattaaag cgtctacatt ttttatcgca aaaggatcga ttacgaaagg
     6901 ctgagtacgt aaattaggct gcatattttg aacgccactc atacgcatca tctgatggcc
     6961 ttttttcatc atgccattcc catgactacg ttttcccgtc ccacaccata gatcacataa
     7021 aatattcgtt ccttcatgac ttttcagcca aattcccgta cagcccagcc accacatagc
     7081 aaaagttcca ggatccacta cttctgtttc gatttcttca ttcaagtatg tgccccactc
     7141 aggaaatgtt tctactaacc acttttcttt tgttacttca ttgacagttt tactcatttg
     7201 cttgctcccc ccatatcgtt gttccaactt acaagtaaat attaatgtgt atcagcatcc
     7261 atggaaaccc ttttatatga ccgtttgttt tttatatgat tttctttcag taatcaatga
     7321 ttgtttcagt ataataaaga cagatatgaa tgtttaaatg aacaactagt caaataaatc
     7381 catggatcaa gatgtccctc aggaggcaaa agtcatgaaa aactcacttg tcaatattga
     7441 aaaacgtcaa aaagaaattt tggaactgct tcagcagact gaacaactat caactttcga
     7501 attagctgaa tcccttgatg tatctattag tacgatacga agagatttaa atttattaga
     7561 agaaaaaaac gagatcatac gcaattacgg ttattgttct tataattaca aaaaccagac
     7621 tgattttgat caatctggtc ctgaaaggat taaacaagcg attgccagag aagctagtaa
     7681 atacattaac gattatgata cgctgtttat caattctagc tcgactgcgt tgaaaacact
     7741 ggattttctt caatctaacc atttgacagt cattacaaac aacgtgaaaa tcaattactc
     7801 tccgcacaaa gataattgta gttatatttt aactggtgga gagatgcgct ttccaaaaga
     7861 agcactagtg ggcgacatcg cattaaatac gatttcttca gtcaatgcag acatttgtat
     7921 cattggctgt agcggagtcg atgtagtaca tggggtcaca acaaagatat taaatgaatc
     7981 aacgatcaac gaaatgatgg tcaacaagac aatcaaatgt aagattttag tcgctgatca
     8041 tcgaaaaatc ggactgacat caaagttcaa gattgctgat atttcagtct ttgattattt
     8101 gatcactgat aaattttgtt ctgaaaaagt attagaggag atcagaaata cggggataaa
     8161 aaccattcaa gtagattcat tttaagaacc aggacgtaaa tatgtaaata ggattatcaa
     8221 aaaaatgaat aacaaattta tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg
     8281 aatcccaaga tgtgtccatc caatcgatac catcataatc tattgcttct tttataaccg
     8341 ttatatgttg cctaaatagg aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca
     8401 cacctccttt tttcgaataa acggtattca aatcagaaca ctgatttcac aaccacttta
     8461 tttcaggtcg ttttcaatca cctttaccgc gtaatcattt ccgttgaaac gcgctatttt
     8521 ttttgcgtcc atatatcttt ctaaataatc atcttctcct aattgcttat ggcaagaagc
     8581 aatttcataa agcaagtatt ccaatgcata agtcgattta tgtttcttat tatactcaat
     8641 acccttctca cataattgga ttgctttatc ataatcctcg attttacggt aataggtggc
     8701 gatatcataa tatacaatgc agaccatcag attatcaaaa tcagtctcac tcaatatttt
     8761 aagtgtacgc tccacataaa ctttcgcaaa atctaattct ccttttgaca agtagatcat
     8821 tgccacgttt gcagctgctt gtaagtgatg gatatctgtt tcggtcgttt gttccaacac
     8881 ttgattaaaa taaaataatg ctgcatctgg ttttttcgca taaagatgat caagcagtcc
     8941 ttgataaaat aaaatttgat ttaaaagatc agaattactt actttttcct gatcgatcgt
     9001 ttgtaaaatt ttataagatt cttggtattt tgatacagaa ttcaatgatt gaatctcatt
     9061 tatttttttc ctgattttgt cttcttctgt ttctactaat atatcggaga tctcgacatt
     9121 cagctttttg caaagcgcac ttaagatatt gatgcctggc gacatattct tgttttcgat
     9181 attgctgaca gttgcttgtt cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt
     9241 tttctttcgg tattctttta gtaatgctcc atctacttta atcaaaacaa tttccttccc
     9301 tttaaaaaat tatttctcct ttatatcata cacaaaaaaa agttctaaac aaccaaaaat
     9361 gtttagaaca gaataaaaat tttaatttta aaataatatt caaattaaac aactggcgta
     9421 tctgctcctt gatttctttt tgtgttatct gaataattat cgtttacagt tataacacat
     9481 agtgaaaatt gtcatggcga gaaagtctaa gaatattttt aaacataact atttctttct
     9541 tacgtgtgta taatgacgac agcacaccta tcaattaata taattatttt attttttatg
     9601 ttctcatgtt tatttttaat gacacaactt ctcgtattta tctggcacaa catataaatc
     9661 gatcaaaaaa ttgttgcgtg tttttttgaa aattggagtt tcaacttgat tacaaaattt
     9721 aaatttagaa gttgtgaaaa cagcgagaga cagtttaata ttcaaaatat acataggcta
     9781 ctcgaacgct gtgtttttta gtatactagt aagaaacgaa gggatagact cattccaata
     9841 aggaggattt catgaagaca attctttttg ctcctgcagt attcaattta gctgagacaa
     9901 cacgaatgat tgaggttgcc aaagctatga aagaccgtta ttactgtgta ttctttggct
     9961 tttctaaaac ttttgctcct ttgatcacag aaagtggctt tgagtatcat ttactagcgc
    10021 cgatccttac gaaaaaacaa gaagaacaaa tcataaaatt tgaccagttg cgtacactta
    10081 aaaacccttt taccaaagaa atggttgcct ctcgtatcac tagtgaacag agtctgattg
    10141 ctaagtttga gcctcgactg attgtgacag gttcgaatgt gacaattttt ttatcggccc
    10201 gcaataaaaa gattccttta gtatatgtta aaccctatgc tttgagtgaa cctttttttc
    10261 aatcagagca tgcgctgatg ccccacgagt tacgtttctt cggcccttta agcaatcccc
    10321 tttggcactg gacaaaaaag cgtatagtaa atacccgatg gatccccaat gccttcaaac
    10381 acgctgcaca aaaagaaatg cttcctttac caaaaacaag tttacaaatg atggatgctg
    10441 atctaaatct catcacaacg cctaaactat ttttggaaga agaacagctg ccggaaaatt
    10501 atcgaatcgt tggtccaatt tttgctaagc tcagtacttc cttgcctgaa gaagtgctaa
    10561 cttttataca gcgaaagcaa caagaaagaa aacgtattat ctatttcgca atgggtagtt
    10621 caggcaatcc gcgtatgtta cgcaaaattt tgttcttctt acaaaaacaa ccggatctag
    10681 cggttattgc acctattgac tatctgcttg atgacattca atctgactca gaagatcttt
    10741 taataacaga atatctgtct agtcatcttt tgcatgaatt cattgatttt tcttttatcc
    10801 acggcgggga agggaccgtc caaactgcct gtgaatccgg caaaccgttt atcggtgtgg
    10861 ggatgcaatt tgagcaaagc tgtaatattg actattgtgt aaaatacgga aacgcaatcg
    10921 ccctcacaaa accagtgact gaaagaaaac tgcagattgc tctgcgcgaa gtttcttcac
    10981 ccaagattcg tcagcaggca cgcacgctgc aagccgtttt tccaataaat ggtccacaac
    11041 aagcaattca agaaatcgaa accttcctga gcaaccaccc aatatagttt caagtagaaa
    11101 aagctttttt aatagagact catcagtaat ttcgctattc gagacccaga cagtgaaaat
    11161 acaaaaaaag taaatagtgg attgaaaagt tagagttact taaattacgg tgtctaaaaa
    11221 acacaaaatc atccttaaaa taaaagatct gacgcaatcc aaatgagcat aggtagcgtc
    11281 tgccatttat tcttagtcaa attctttgac acctttctct ggttggatca tctcaacgtt
    11341 tcttcaaaag aaagaccata ataattaggc aaatacattt tcttaaaatg tgtcatatag
    11401 atctagaagc atcgctttgt agagatttgt gctgctagtc ccttcaacaa ttactaaatc
    11461 aaatgtagga tttaccactt tatctttgat aatcaacctc cctcttctgt tgagacaatg
    11521 atctcgcaat ccgatgcata ctcctatata aactgccagc aatccccaca tgctgagtag
    11581 atcatgtcag aatgttctat gtcgtcagca acgataaact aaaagtcacg ttcaccatga
    11641 ctgattgcta ttcccagcgc aattatttct atacacgttt catgatttga ataaacactc
    11701 tcatcataca tattaccatt catacaccat actgcagccc ctactatatg gttgtaagct
    11761 cccaaatcta tatttgcctt gatcactttg gtagtagatc gactaattct taatccattg
    11821 ctgataaaat tttcattttt gcctccttct ttctgccaaa acagttaaaa caataataat
    11881 ctttatgtaa aaaagggctg tgacaaaagc cttgtcacag tcccatattc cgaataaacg
    11941 gtggtcaaaa gcttgcatct gcggtaataa gttcaaccaa acgaaaaata agccaacatt
    12001 tcacaaaaat ttaagaagca attttcgtaa atttcttctt atttcttgaa gctaaccact
    12061 tctgtcacaa ccacttttag aacatttaaa gcttcgatgt gacaaaccat ctatgctgct
    12121 cgatcataaa attgatagca aaaattccac aaagtacata tgtcccccat gaaaacaaaa
    12181 cattcatatg cggtacaatg atctttggaa gaatcacgat caaaaatgat gccagtgccc
    12241 aaatccatcg attgatttga atatgatatg tagctagcat attcaatata aggtgactag
    12301 ccgttaataa aaagataaaa acaaaaaata aaatcagcca atacattgtt tcccaccttc
    12361 taaaaaccaa acttagacag tttggacttc gttttctcca cgactttgtt catctgacag
    12421 catcttttta tcataagctt ttacaaatgg ataatagata ataaatgcta tcaatgtgtt
    12481 gatcatgatc aagataacaa cacgccagtc atttcctgct gaaagataac cgccgattgg
    12541 agctggtaat gtccaagttg gcaaaacagt aaatctattg accatttcta atttgactgc
    12601 aaaataactg ataatagtca aaactaaagg aactaagttg aacgggatga acatgtaagg
    12661 attcaacatc ataggagctc caaaaatcat gggctcattg atattgaaga taccaggaat
    12721 aatagaaaaa cgaccaacct ctttcaagaa ttttgattta cagaagaata taaacaaaac
    12781 agataccacg atcgttgctc ctgcaccacc aattgttacc gtccattgat aaaactgttc
    12841 aggagcgata tagggtaatt gggtggcagc tgtaccatct gccaatgcct ttgcattctc
    12901 atccaacatg atcagccaca ttggacgaac aacagcccct acaatactca tgccatggat
    12961 accaaatgac cacaacaaat ggatcaaaaa cattggtagt aaaacaccaa gcaaattatt
    13021 ccctaaaata ttggttaaag gctcgaataa cgataataag gtagcgttta catcaaagcc
    13081 cgcgacgctt cgaatcagcc aagtaattgt taaaatgact gcacctggaa tcaatgcctc
    13141 aaaactacgg gcaacagcag gtggcacttg ttctggcatt ttgatagtaa tatttcgatt
    13201 tttaaagaaa cgatatactt ccactgcaaa aatcatagat aagatccccg caaacatccc
    13261 agatgctccc aaagaactca taggtaagac ccagccaaga ggtgcctttt caggagttaa
    13321 aacgtttaca ggaacttgta acataaagaa cgttcctaaa gataatatac cacctgtcac
    13381 actatctaat ccatatgatt tagctagatc cgaacccata acaaaagttg cataaatagc
    13441 catcaatccc atcgtcatcc taaaaggtaa aacaatcgtt gccgaataag gggcaataaa
    13501 ttcattccat ccaggaaacg gtaaattgat aaagaccata aaaaatgtcc caatcaaaat
    13561 caatgacaat gttgaaacaa ccccattacg aattgctaat aaatgacgct gtgtaccaat
    13621 ttttgccatt ggtgggacaa gtttctcttc gacccatttc atcagctttt ccactaaaac
    13681 cactcctttt caataaaata tgaaccattc attgcatgac aacgcaaaga atgttcataa
    13741 ctaatta
//
LOCUS       DAZKCW010000061        13584 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000061 DAZKCW010000000
VERSION     DAZKCW010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.062"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            332..1243
                     /locus_tag="ACG84Z_002175"
     CDS             332..1243
                     /locus_tag="ACG84Z_002175"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9162984.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            1460..1897
                     /locus_tag="ACG84Z_002176"
     CDS             1460..1897
                     /locus_tag="ACG84Z_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162985.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            1992..2876
                     /locus_tag="ACG84Z_002177"
     CDS             1992..2876
                     /locus_tag="ACG84Z_002177"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFP9162986.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            3100..6267
                     /locus_tag="ACG84Z_002178"
     CDS             3100..6267
                     /locus_tag="ACG84Z_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFP9162987.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            6335..6832
                     /locus_tag="ACG84Z_002179"
     CDS             6335..6832
                     /locus_tag="ACG84Z_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HFP9162988.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            6851..7315
                     /locus_tag="ACG84Z_002180"
                     /pseudo
     CDS             6851..7315
                     /locus_tag="ACG84Z_002180"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            7312..8070
                     /locus_tag="ACG84Z_002181"
     CDS             7312..8070
                     /locus_tag="ACG84Z_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFP9162989.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(8156..8896)
                     /locus_tag="ACG84Z_002182"
     CDS             complement(8156..8896)
                     /locus_tag="ACG84Z_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFP9162990.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            8957..10210
                     /locus_tag="ACG84Z_002183"
     CDS             8957..10210
                     /locus_tag="ACG84Z_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFP9162991.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            10532..10759
                     /locus_tag="ACG84Z_002184"
     CDS             10532..10759
                     /locus_tag="ACG84Z_002184"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFP9162992.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            10882..11208
                     /locus_tag="ACG84Z_002185"
     CDS             10882..11208
                     /locus_tag="ACG84Z_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFP9162993.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            11276..11989
                     /locus_tag="ACG84Z_002186"
     CDS             11276..11989
                     /locus_tag="ACG84Z_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFP9162994.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(12179..13480)
                     /locus_tag="ACG84Z_002187"
     CDS             complement(12179..13480)
                     /locus_tag="ACG84Z_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFP9162995.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         4622 a         2283 c         2803 g         3876 t
ORIGIN      
        1 aatgtctgga aaatcgaaca taaaagtgtc tgatttgaat atcccagcag cggaagaaga
       61 aaaacaaaat cgataacatt tgttctaaga attagttacg ttaaatacgg aacgcaagat
      121 agacttgaaa aacggtaaca aaagaagtag tatattaagg tgtgatgtgc tacttgacat
      181 ttattctgct gagcgaactt tctggattgt gtagccttat atctattcag gacgtatcga
      241 gcagattagt aaaggtgttc ttgatgattt tcatcttgaa cacctttgtt tttagcaatt
      301 cgcaaaaaac gaaaagtagg agaattgata aatgaaaaaa agatttttag cacttgccat
      361 cgtactaggc actggcttat tgtcaggctg tacgaatgcc ggtgaaaaaa cagccgttag
      421 ttataaaggc ggtacaatca gcgaacaaga agtaatggat agcttgaaaa aaatgcaagg
      481 agcagattcc gctgtgcaac agttgatcgt ttatcaagta tttgaagata aatatggaga
      541 tgacgtatca accaaagaaa tcgattctca atatgatcaa acaaagaaac aattgggtga
      601 ttcatttgat tcacaattga aatctgcagg ttacacagaa caaacattca aagacagtat
      661 caaacaaagt ctagcctttc aagaaggtct aaagaaacat atcaaattga ccgatgaaga
      721 tttaaaaacg gcttgggaat ctttccatcc agaagtggaa gctcaaatta tccaagtagc
      781 aagtgaagat gatgcaaaag atgtgaagaa agctgctgat aagggagacg atttctctaa
      841 attagccaaa gacaagtcaa ctgatactac gacaaaagaa gatggcggaa aagtgaaatt
      901 tgattccact actacaacgg ttccggcaga agtcaaagaa gcagccttta agttgaaaga
      961 tggtcaagtt tctgatgtga tcacttctac caatgcttca acttatacta cggaatatta
     1021 tgtggttaaa atggtgaaaa accaaaacaa aggcaacgac atggataaat acaaaaaaga
     1081 attgaaagaa attgcaacag acacaaaatt aagtgacagt accttccaga ataaagtaat
     1141 tggcgaagta ttgaaagacg ctaatgtaaa aatcaaagac aaagactttg aaaatgtttt
     1201 gagtacattc acttcagatt ctagtacagc aagtagtaaa taagcggtat aaataaaaaa
     1261 tatgaactat ttaaatcaat aaaactgttc atctaaatct ttttattaga actaaatcaa
     1321 cagtagttta attactactt gatttagttc tttttatttt aaaaattttt tttacttaga
     1381 atccagcgac cctagatatt tttctgtata atcttaaata aagaaaacaa tatcaaaaaa
     1441 tgcacgtaga agtagataaa tggagtggtt ttgcaaattt cttttatttc tagaagttat
     1501 tcacgtatac ggatttgttt ttctcacaaa taaaaaggca ggaagtacaa tggatcattt
     1561 gtatataaaa tatattcatc aattttccgt tttggtgtta ggcacactaa ttatagcggg
     1621 gattgtcgca tttattattc aaggccgtga catattaaca gtacatcaag agtttttcag
     1681 ttatgcattt ggtattcctc tgatcgctat aaggtctgat aacaaaaagt ggaagaaacg
     1741 ctattacatt ctcttgctat ttttgtgttt ttatctgcca cctaagattt ttactttatt
     1801 aggtatacaa tgcctatcat tttcttttat ttcctatatc attgttttaa ttttcctcag
     1861 tttcatagta tggatgtttt atcttgtcaa aaaataaatg aatgtttcat gaacagtact
     1921 tcatcacagc ctaatttttt tctttatgct atcgttatat taaagaaatc aatcagaagg
     1981 gaaagaaagt gatgaaaaaa gttttattag tggtaaaccc cagttcaggc ggtgaacaag
     2041 caaaggaatt tgagcaatta gcgatagcaa aattggaatc ggtgtttgat gaagtggtcg
     2101 tcttgcatac aaaaaaagca ggggatgcaa aaaactttac tcgcgaagcg gctacggaag
     2161 ggtatcatag tgtgtttgtc atgggcggag atggaacagt caacgaagga atcagtggaa
     2221 tcgctgaaca agaacatcgg ccaaatttcg gatttttccc attgggtacg gtgaatgact
     2281 tggctcgagc attagggata ccgctagaac ctgaggaagc gatcaatcat ttttcgattg
     2341 aatcagtcaa gccattggat attggaaaaa taaatgacga ctattttatg aatgtcgtcg
     2401 caattggctc tatccctgaa tcaatcaatg atgtagatgc ggagaagaag acgaaatttg
     2461 gaaaactagc ttatttcatg tcaggaatca aacagttagc ttccacacaa tcctactcgt
     2521 ttcacgtaga agttgatgga aagaaggaag aaattgagag cagtaccttg ctgataggac
     2581 taactaactc agtcggcggt tttgaaacat tacttccaaa tgcaaaagtg gatgatggta
     2641 agctccattt ggtttattta aaagattctt ctttgatcga tacgcttaaa acattgccag
     2701 acctattaaa aggagtagat gaatctacga aaaatctagc ctaccttact tgtgagcaat
     2761 tagttgtgtc attagctgat gaggaagaat tgacgacgaa tgttgatgga gatgaagggg
     2821 ataaattacc tgtgacaatc aaagtattgc cctcacattt acaggtttat tgttaaaatg
     2881 gaggttgtga ccgaggagtt ggcgggagaa caccgcttgt tcgggataag ggactgtgac
     2941 aagacttttg tcacagcctt ttttttgtac aaaaaagaaa tttacaccta atagaaaaat
     3001 ttttccataa aaatacatat tttaaatatg aaagtacaat tggaaataga ttaaaacgat
     3061 aaaataaaat tgtcaaaacg tcagagagga tggtggagaa tgaatcaatg tgtaaaaaag
     3121 ctgattgcgt cgattttgtt tgtcttccct ctcttgatgg tgacatccgt ttttgccgat
     3181 gtagagaaaa caaacgaatc aacgcaatca gagaatcaaa gttttgacaa gactactttt
     3241 tcagaagaat cgattacttc tgaaactaca gaatctcaaa gtgaggcttc tactaataaa
     3301 aggcaagaag aaaataagac aagtgagacc tcagaagtag ctgaacaaac gtctgatagc
     3361 agtgaagcgg cactggcaag agctgtttca gcggatgggt acagcgaagc tgccacaaca
     3421 gaagaactgg cgcagcttct cgcagacgaa tcagtaacta agatccgact gattcagcct
     3481 ttgactttag acagggaatt agagatcaaa cgagatatcg ttattgattt tggtggattc
     3541 gctcacaatt tcggcacaca ccatatttat atcaatgaga tacctcagtc gatcgagttc
     3601 cagaatttta aaggaacagc tgcacatcca ggtggattga caccaaatat cgatggaaat
     3661 gccattatca ttgcttatat gaccgatttt tggggaagca gatatcattt tacgggagaa
     3721 ataaaattta ccgggacact tgatttgtat gatgggtcca aattaggact gatttacgct
     3781 cctcgtgcaa ctgtcacatt agatggtgtt tccggtgtgt tggatgtcca accagtgaag
     3841 gaaggactga atgccgctcc gggtaaagcc tatttttgta gaagctatca attgaatgtg
     3901 atcaatggta gtcaacttta tggaccgtat ctagggaaat tctacggttt tctagattca
     3961 ggagatgaga ctggtagtgg aaaaacagcg ccaggaatcc atatcttaag cggttcaaag
     4021 gtctctcttg attatgatcg ggcagatggc gttagcgatg aaggagaggc agtcgatacg
     4081 ctacctggta atgtcatgtt tgaagtcagt ggttcgggaa gcgaattttc ggtaaataca
     4141 aagatcaata ttaccaatga caacaatcgc ggaatcatcc aaatgagagg ttcaggatcg
     4201 aaagtcactg tatcgaatgg tgggaaaatc accatcaata cagcaactac gggcggattt
     4261 cgcttgcaag gagattctag tcaaatccat gtatcaagtg gtggacaaat ctcggtcaaa
     4321 atggctggag atgacgatca acccgggaac aatgggatgc gttttgtagg aaaaggcctt
     4381 tctttgatcg tagaaggagc cggatcagtt atcgacatcg ataagcagag tgggcgttcc
     4441 agcgcagttc gttttgagaa tggtacgcaa aagctgacag taaccaatgg aggctcattg
     4501 agggtaagaa atacaggtga tggcaaatct tacgtgaaca gactcaatca aggaaatcaa
     4561 gcgatccaat tttatgacgc ttctggtttt ctagaaagtc caggttcagc tgattttaca
     4621 gtcactggag aaaaatcaaa tatcgatata cgcgcagatt ccggagcaac tgtagataca
     4681 actggagata ttgatttaaa ttttacggca ggtgaaaaaa cttatttagt catggtcggg
     4741 aaaacagggg aagataagac cggcatcatc agtggggatg tgttgaatgt ggacttagaa
     4801 tctcctacct attttgattt ccaaaacaaa cggattggaa gcgagaccaa tggcataggc
     4861 ggctgggtat tccaaggaaa tggagattct tctttaaaga tcgcccattc agaaatcgct
     4921 ttatggcgaa aaacaggcgc aacattcgat aactttgaaa aagacccgga ttatttttct
     4981 gatatgacag acttatcgat caatgggacc gacttaggca atttcgtatc aagccctagt
     5041 gcaggtttaa caaatgaatt tgctcagaca ggtgccggaa tgaaaaatta taatcgaatc
     5101 agtgccaata atcagctccc gatgattgaa tccttaagag tgccaacgaa tgcagataaa
     5161 aaaatctatg ggcatgtcgt tgttcccgaa ggtgtcgagg caaagccaag agatgcttgg
     5221 acaggcgaag tagaagtgac tttacgtatt acttacgcag atacgacgaa atcatctgta
     5281 gaaattactg ctctcacgca aggacaaaca gatgaaaatg aaggggcagg atataaccca
     5341 tggggagaag gcgaacaagg cggcttgttc gaagttcaag tacccaatga tgagagatta
     5401 aaaacggagg atcaagtgca agttgttgct gctaaaaaag taagaggtgg ccaagaagtg
     5461 acagaactgg actctgccaa aacgacagtc gatgtgattc ctcctgaacc tgctaattta
     5521 agtaccacat tgatcaatgc agcttctcgc acgatcacag gtacaggtga agcaggagcc
     5581 ttggtttcat tgaaaaaaaa tcaagctgtt ttgtcagaaa caactattga tgatacaggg
     5641 gaatttgttc tttctatccc agaaaatcaa ctttttgcag gagatgtatt agaaattgta
     5701 ttaaacgacc aagcaggaga agctactgct aagggtgtgc agaacaagcc aagtaccaac
     5761 gatgaaattg ggaatcacaa tccaagtgat acgccagttg tttatcatga tgccccgcct
     5821 tttgcacctg ctacgaagat cgtagtagaa ggtggtctct catttcttgc cccttccaaa
     5881 ctcgattttg gtcagatcaa agcaactggt ttgacacaag aagcatttgg ccaaatggat
     5941 atacaggaaa aattatggat ttatgatcag cgagaaacga aaaatccgtg gatcttaacg
     6001 ataaaattat ctcagccttt cacaaatgat gcaggatttt ctatgcagga tgtcctatat
     6061 ttcaagaaag gagaggagta tcaattagtg aatgaagaag aactggaaat tgtcagagga
     6121 caaaattcaa cgaatgtgca agcagattat tcagaatatt taaataacgg tcgggcgttt
     6181 aaacttgtct taaccaaaga aaatcagata gctggtaatt actcagcaga gataacatgg
     6241 acattagcag atgcgccgac agaataaaga tcaaggagga tgattgatga atcgaatatg
     6301 gaataaaagt catcgaaaca actgctcttt acttatgatc cttctccttg gattcatcct
     6361 ttggcagaca cctgtccatg cctccgaatt caattttgcg gtagattttg aattaccggc
     6421 taatcagatt gataagaaca aaacatatat aaatgtaagg atggagcctg ggaaaacaca
     6481 ggaaatcccc tacacggtct ttaaccgaac agataaatca gtaacagttg agacattgat
     6541 ccactccgct acgacgaatt caaacggtgt gatcgaatat ggagaatcaa aaagtaaatt
     6601 tgatgaaaca ttaagttatg atatgaaaaa cttagcaaaa acagtgggag aaataactgt
     6661 tcctcctcaa agtgcggtca ctgagacact ttcactgaaa gcgccagaaa aagagctggc
     6721 tggtgtggtc gcaggaggga tcacgtttca agaaaaaaaa gagaacgttt ctaacaaaag
     6781 tacagttggt gtcgtcaatc agttttctca agtgaaagca atcttgattt gaaatagcga
     6841 aaaagagtct tccccagatt tgaaattaaa aaaagcttat gcggatcaaa gcgatggaag
     6901 aaatgtgatt aaggcgaatc ttcaaaatcc aaatgcttct tatatgttcg gcttgactac
     6961 atcggttgaa atctacaaaa aagaaacaaa agagccttac ctttcaataa aaaaagaaaa
     7021 aatagatgta gcacccaata caaattttga tttacttgtc ccattagaag gaaaaaaatt
     7081 agctccggga cattatcaag cggttgtgaa gggtgcttgg aaagaaaaac gctggaatct
     7141 ccataccgat tttgaaataa ctgatgatgc agcggaccaa ttgaatgaaa aggatattga
     7201 tttaaaaaat cagccagaaa catttgactg gcgatggctg atacttgttg gagtcattct
     7261 tattggctta tttgctggat tatttatttt aaaagaaaga aggaaaaaga aatgaaaaaa
     7321 acaattgcat taagtaccgt tctagctgga agtctattat tatgtacaca aagtgttttt
     7381 gctgagaata agagctcagc cactacagaa ggaacgattt ctgtgaccaa accagatgct
     7441 gcaaatcctg aagacgttgt tccagttcct cctgttgatc caaatgatcc tgatactcct
     7501 tttacacctg acgaaccaaa tcagggaaca tccggattac tgacgattga ccaagctcca
     7561 gatcttgatt ttggaacaat caagttaggt acagcaaaaa cagtatatgc tgcattacaa
     7621 agcggaacgg acagtactgg agcacaaaca caagtacaga atttcgtaca agtaacggat
     7681 aaaagcggaa attatgccgg ttggaaatta tcagtcaaac gaacagaatt tattggtaca
     7741 acatctgata cgaataaact aactggttca aaggtgaaat tcaaaaacgc cgtgattcga
     7801 aatagcgcaa ctaatagcag tggaatgcca tctaccgttt ctggaactgg cgctgaagga
     7861 atcgaaatcc cagcagatca ggcagtagat ctagtaactg caggagcaaa tgaagggatt
     7921 ggcacatgga tttattcatt aggagagaat gtggaacaag ggagacaatc agtggaatta
     7981 tttgttcctg tatccaatta tgctgtagac aactacgttt caacattcac atggtcgtta
     8041 acagatgctc ctacagaaga ggaagcgtaa aatcatatca acgatttcag ggagtggagc
     8101 cgattcaagg cccactccct gaaatctgct atgcttacgt ctcagctctt attcatcaac
     8161 tcgaagcagt tttttggaag tcatggaaac gttcctttgt cttttcaaag atctttcgac
     8221 caacgagtaa ggagtcaccg ttgaaaaatt ctaacacata atgagcagaa tcaattttct
     8281 gcaattgcga taagttgata cagtaagatt ttaaaagtaa aaagtaagca tacttttcta
     8341 actctgtctt caattgtttt aaagaagtat tcactaattt atcttctgta gttgttttga
     8401 ccataacttg gtttttcaaa cctttgatac tttcaatata taaaatttcc cgaggataca
     8461 ggacgagact tccacctttt tgatcaataa agattttatc gacatttacg atctgctgtt
     8521 ctttccaatt gatctgttct agcacttgac gaatttgttc agataaattc ctgtcttttc
     8581 tgatatatcc aatcggaagg attttccgat tgatgatctc tactgcaaaa ttcgtataag
     8641 cggtgaaaaa aacaatatta ctatgtgcat tttttttacg tatttgttcg gcgacatcaa
     8701 tacctgtgag tgattgcttc aagtcgatat cgataaagaa aacatcgtga ttatcaatag
     8761 tgcccaactg gatcaactga ttgatttgag agatagaagt gagctgcacg atattctcga
     8821 tatgatgatt gaccaattct ctgatgatcc attcgctgtg aaactggtta tcttctatga
     8881 taaaatactt tttcatatgc aggctcctat taaaaaaata tgtgtacatt ttgaaacaaa
     8941 acaatggagg aataagatgg tcgcaacagt gacactttat ttgaccttta ctttgatttt
     9001 agatttaggt atctatttat tcttttcgaa acaactgcta gtaaaaaaca gctttggttg
     9061 tatagctttg atggtggtga cacttttact tcctatccct aaagtgagct ttccttacct
     9121 agttggctta ttattgatgt ttctttttta ttttactacg aaaaacctgt ttatcagctg
     9181 tttgatcagt aatctttttt ttgctatcac tggactcagc ttttttctgg tttttgatct
     9241 gatggattat ttaggaaaga gacatcttgg aacagcaagt ttttttgcac tacttatcgc
     9301 atttattttc tatctattag taaaaagtat agacaaacag acgagatttc tcaacttgct
     9361 ttttacttat ccaactgaac actattttgg aggtatttgt attttattaa gctggggcgt
     9421 gatttacttg gtattgggaa gtgttcactt ccgctcatct aattatctgc ttctatctct
     9481 tttgtcgata gtcatcagtt ttttttcttt gtttttttcc attatgttga tcagtttcca
     9541 agtaaaagaa agacaacatc aggaatcgct tcaactgtat caaataaatg aagaatatta
     9601 ccatcatcta gaggaattca aacatgatta taaaagtcta ctgttttcat taaaaattac
     9661 tcttcaggaa aataaaaaag aaacgttgga atttttagaa atattagaag atcattctgc
     9721 agctattttt gaaaaaccgc aaatacaaca gctaacaaat attgtatccc cagctgtcag
     9781 gggtgtcttt ttaaaatttc tagaaaaagc agaatcggag aaaatcccga tccaagtagt
     9841 tattcctgtc gaagtgaaaa caatcccgat tgatctggtt gtttttattc gctgtttatc
     9901 tatttttatt tctaacgcat tcgatcatcg tgtagccgat cagagtccga ttacgatcaa
     9961 tctgctggaa gaaaaagagg gatcacgttt tagtatagcg aacaaggcaa atccaacgaa
    10021 tttgacgcta tcggagatgg tcaaaagagg aaaaacctct aaaaaaaatg gcgggttagg
    10081 tctatacagt gcgaaaaaaa tgttggatgt ttacgaaaat gcagaactaa aaatcgaatt
    10141 ttcaaaacag aatcactatt tttttgtaga aatgtatctg gcatctagaa agagcaaatc
    10201 agcctactga cttactgtca aaggataagt ttgaggaaag tctacacgga gatagagaca
    10261 acaacacagc atattcaaaa gaaacagaag cgtgatgacc gttgtcaccc ttctgtttct
    10321 tttgctatgt agttaaacaa agtagttgac acttccgcta cttagtatta gtacgaaagt
    10381 atacttcatg atactaagta gataagaagt gaaaagcgga acccacgatc gtcaaaatgc
    10441 taactgcttt gcttacacca gataaaggga agagcaatat cgcttatttt aggcgtggag
    10501 aagcaagcaa atccctacga tcacaaaaaa aatgctgacc cagcagttaa gagagttaga
    10561 acaagatgaa agtatccatc gaaaagccta taaccaagtc ccgcctaaag tagagtactc
    10621 gctcaccgaa gaaggaaaat cattaagaga gattctagta gcgttgtctg tttgggaaga
    10681 agaacgtatc gaaaaacaaa aagcctcaag ggaagaagac acgctactgc atacacatgg
    10741 tggctaccta aattattgat tttctatgac atttatttta aataaaagaa aacaggagtt
    10801 tttttaaaag catcatctat tttttatgta aaaaaatggt atgattaatc aagtaagaag
    10861 tgattggaag aaggcaagca aatgaatagt atggaaaaag tcaaccagtt tagagatgaa
    10921 cgtaattggc gacaatttca taacgaaaaa gatttggcta tctctatttc tttggaagca
    10981 tctgaattgt tagaactttt tcaatggaaa acgccggaag aagtaaaaga aacacaatta
    11041 gaacgaatca aagaagaact ggcagatgta ttgatctatt catacatgat ggcagacaac
    11101 cttcacctgg atctagatga gatcattgaa gaaaaattga tcaaaaataa tttgaaatat
    11161 cctgtagaaa aaagcgcagg tgtacgaaaa aaatacacag agttgtagaa atgtgtcatt
    11221 cggctgttgg aaagagcaaa agaaaaacag taaaatgagt ctggagggag agaaaatgaa
    11281 aaaaaaagga aaagcaaaaa gatggctagt caatatcctc ttgttcctct tgttattagt
    11341 aggactagct ttgattttca atgaacagat caaggattat tttgtcagag agacaggaga
    11401 taaatatgct atagcgaatg taacaaaaga agatctgaaa aagaataacg ataaagatgt
    11461 cagttttgac tttgatgcgg tagaaccaat gacgacagaa ggggtcatga ggtcgcaaat
    11521 gagaggaaca gatctaccag tgattgctag tatcgcagtc ccttcagttt caatcaattt
    11581 accggttttc aaaggcttgg ataatacgtc actactttac ggagcaggaa cattatctcc
    11641 agatcaagaa atgggaaaag gaaattatgc cttagcaagc catcgtgcaa cgaaccctga
    11701 attgctgttt acaccgctag aaaatttaga gatgggtgcc aagatctatt tgacagattt
    11761 agaaaatgtg tatacataca aaacattttt taaagaaaaa gttgctccta cagataccca
    11821 attactgaat gaagtcgagg gaaaagaaat tgtcacacta attacttgtg gcgacatgga
    11881 cgccgtcacg cgactagttg tacaaggaga actggaaagt gttacatcga taaaagatgc
    11941 gacagatgat atgagatctg ctttcaatct agagacaaaa acattttagg atactgggac
    12001 ataagtcgtt acagattaaa aacagccaaa ggatatgaat cgataaggaa aaaccaattt
    12061 gctgaaaaaa agagaaacgc aaagaggtgc atctctgatt tggttgtttt ctggctcttt
    12121 gtcaaatagg actgatagag tgagataaga acatctaagg tagaattcct tttctacttt
    12181 agatgttttt tgattcatag gtaatcagat tatttagtaa gaaaattctg gtcttcattt
    12241 tccgaaagct tcgaaagcca taagcgactc gtttcaatgc tttgatgtgg gtatgcagat
    12301 tttctatttt ggcatttgaa taaggcaatt cgagggctaa acgaatgccg gattcatagt
    12361 ttataaaagc tttttttata gaatgcagtt cttttggaac ggaattgggc atcgttctta
    12421 caagtttaaa gaaagtgtcc gcctctttgt cgtgaaacgc ttgaagaatt tcttgatagt
    12481 aaaaataggc gattcgtaat tcgtcagaga tcgaaagcag acgatccacc acttcacttt
    12541 cggtgagata cgcccaacca aaattgcgcc atttggtcca tttgtcataa acaagcttgt
    12601 cctgtcgttt gatcagaagc cgagacaacg cctttaattg tcgataatat ttggcttgtg
    12661 ttggatcgtt tcgatcaaag cttttcatga ttcgtacgcg aatatcctca aatttacgaa
    12721 tgagatgttt gacaatgtga aaacgatcca caacgagttt tgcctttgga aaacattcct
    12781 ttatcagaga ggcataagaa acattcatgt ccgtcacgat gacctttacc ttcaatcgtg
    12841 cgcgtcgttc aaattgcata aaataagaaa cgagagcctt tttcttccgt gaaggaagaa
    12901 tatccagtaa ttttccagta tcgccatcca tacaagaaaa ggagtaggga ccgacttgat
    12961 ttttcagtga acgaaattca tccattaata aacaacgcgg taaccaattt ctttttactt
    13021 ttgtcatggg gatcagagaa gcgagtgtcc gagaaacggt cgaccaagaa acgccgcaat
    13081 gcttagcaat tgtcgtcatt gcttgttttt cagttagctc ttctaaaatt ttatagcgca
    13141 cttgtttagc gataaagcag tttctatcga caatgtaggt attcgccgta aaataggtgt
    13201 ggcagccacg acagtggtag cgttgtttcg ctaaagcaag ataagtcagt tggttcgcac
    13261 atttattaag ttgaatgagc gattttttct ttccgttctt aacgatcatg ccttcatgat
    13321 tcatctgttt acacaaagga cagcgacgaa tttctttact taacgtcgca gaaacaacaa
    13381 gactcttgat attcttaatg ctcttcgatt ccacatttgt gatgaaaatg tttttatctt
    13441 tgattccaag tagtagtttg atatgatgaa gatcaggcat acagaacgct cctttgattg
    13501 tgttgtggtg attcaattct aacggagctt ctgtatgttt tgttttttca tgctcaaaag
    13561 ggaccgatag aatgattttc tatc
//
LOCUS       DAZKCW010000062        13524 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000062 DAZKCW010000000
VERSION     DAZKCW010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.063"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(48..1127)
                     /gene="uxuA"
                     /locus_tag="ACG84Z_002188"
     CDS             complement(48..1127)
                     /gene="uxuA"
                     /locus_tag="ACG84Z_002188"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFP9162996.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(1130..2761)
                     /locus_tag="ACG84Z_002189"
     CDS             complement(1130..2761)
                     /locus_tag="ACG84Z_002189"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFP9162997.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            3065..3736
                     /locus_tag="ACG84Z_002190"
     CDS             3065..3736
                     /locus_tag="ACG84Z_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9162998.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(3896..4087)
                     /locus_tag="ACG84Z_002191"
                     /pseudo
     CDS             complement(3896..4087)
                     /locus_tag="ACG84Z_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(4455..4796)
                     /locus_tag="ACG84Z_002192"
     CDS             complement(4455..4796)
                     /locus_tag="ACG84Z_002192"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9162999.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKDY
                     SALGLFSIGYW"
     gene            complement(4893..5345)
                     /locus_tag="ACG84Z_002193"
     CDS             complement(4893..5345)
                     /locus_tag="ACG84Z_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163000.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(5352..5900)
                     /locus_tag="ACG84Z_002194"
     CDS             complement(5352..5900)
                     /locus_tag="ACG84Z_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFP9163001.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(5945..6277)
                     /locus_tag="ACG84Z_002195"
     CDS             complement(5945..6277)
                     /locus_tag="ACG84Z_002195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163002.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(6291..6548)
                     /locus_tag="ACG84Z_002196"
     CDS             complement(6291..6548)
                     /locus_tag="ACG84Z_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163003.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(6743..7285)
                     /locus_tag="ACG84Z_002197"
     CDS             complement(6743..7285)
                     /locus_tag="ACG84Z_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFP9163004.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(7306..8397)
                     /locus_tag="ACG84Z_002198"
     CDS             complement(7306..8397)
                     /locus_tag="ACG84Z_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFP9163005.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(8405..10615)
                     /locus_tag="ACG84Z_002199"
     CDS             complement(8405..10615)
                     /locus_tag="ACG84Z_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFP9163006.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(10631..13159)
                     /locus_tag="ACG84Z_002200"
     CDS             complement(10631..13159)
                     /locus_tag="ACG84Z_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9163007.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(13211..>13524)
                     /locus_tag="ACG84Z_002201"
     CDS             complement(13211..>13524)
                     /locus_tag="ACG84Z_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFP9163008.1"
                     /translation="VNAATFLLVVIFEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCV
                     LALAKLKPDGKKVHFYLWDWFCYMIRMMNGDCVYYNWDKVSNNALEELLFVNKYVYLE
                     D"
BASE COUNT         4286 a         2786 c         1874 g         4578 t
ORIGIN      
        1 gtttttagaa gagaaaattt ttcctctaaa taaactccct tatataatta tttactcgcc
       61 cccttttcaa gcgcttccca aataccattt aaataaactg cacctagagc tcggtcatat
      121 aatccataac caggtctacc ggtttctccc caaatcatcc gaccatgatc tggacgaata
      181 tagccattaa atccattatc gtacattgtt tttaatatct tatacatatc tagagaacca
      241 tattctgatt tatgcggcgc ttcgtaaaaa tcgagtccat tgtcacttaa atatttgata
      301 ttacgaacat gtgcaaaagg aatccgatcc cgttgacaaa attcagatag aatttcatag
      361 acatcattat ctggtcgttc tgcaatactt ccagtacata atgtaatacc attagaagga
      421 gaatccacta cattacacaa ccaatctaaa tcgtcacgat ttttaacaat acgaggtaat
      481 ccgaaaatgg aatatggtgg atcatctggg tgaactgcca ttttaatccc aacttcttca
      541 catgtcggga taattgcttt gagaaaatat gcaaagttct ctcgtaattt ctcttcatca
      601 acttctttat aggcttctaa taattgctta atttgtgata accgatgagg ttcccaaccc
      661 ggcaattcaa aattattagt agaattttct acttctctaa taatttcctc cggatcagta
      721 gggatatttt ttgaaatata ggctaacgta gaagacccat catctaaacg ataatccaaa
      781 tccgatttta cccaatcaaa tactggcata aaattataac agataacctc aatcccaaat
      841 tctgccaaat tgcgaatcgt ctgtttataa ttctcaatgt attgatctcg tgttggtaaa
      901 ccaattttga tatcatcatg aacattaaca ctctcaataa ctttcaaggt aagtccattg
      961 gcttcgactt catcttttaa agatttaatt cgttctctcg gccaaacctc tccggctggt
     1021 atatccatta atgttccaac aattcctttc attgctggga tctgacgaat ttcttgtagt
     1081 gagatttttt cttcatttgc cccataccat ctaaaagtca tttccatagt tactttcctc
     1141 caacttctgt tatatattta ttgattgttt tacgaactgc ttgaggacct actagcattt
     1201 cgcaaaagat tttttcagtt ttctttccta ccccaacttg atataaatct aaaccaaaga
     1261 tttctttatt ttctaaaatt tcctgtaccg cacaatgaat ctttgaagga tcttgttcac
     1321 ctaatttcaa tactgataat ttatcctgca actctaccaa taacggatca ggacttggca
     1381 caaaattttc cccttgatca tcgactgcca gtaaataacg taaccaagca gcaatagcga
     1441 taggaataaa tgttagattt tctgcatttc cgtctttttc gacatacttt ttaattgttt
     1501 caccatagcg aatcgctact ttttgagaag tatctgttgc aattcgttgt ggtgtatctg
     1561 gaatataggg attaggcaaa cgtttattaa ttacttcatc aataaattgt tttggatcaa
     1621 taatgcctgg attttcaact actggtaaac cttctaaata acctattcct ttgattaaac
     1681 caaccaaatc atcatcctgc atctctgctg aaattgattg atatcctagc agacaacctg
     1741 ttactgccaa agcagtatga agtggattca agcttgtcgt aaccttcatg atgtctgctt
     1801 tatcaaccgt ctctctatct gtcataatca caccagcctt ttccaattta ggccggccat
     1861 ttggaaaact atcttcaata actaaataat gaactacctc agtattagtg aaagcagcaa
     1921 tattggtatg tttttttgtg tgaatgatat ctaaatcctc gagccccatc atcaatagat
     1981 cttcctttac attctctgaa ggatttggcg taattcgatc aatcatactc caaggaaaag
     2041 tcactttttc tttatccttt aaataagcaa taaatttttc agaaacatat ccttcttttt
     2101 gccaagcttc tgcaatcgta aaaatactat cttgaaaacg ttgaccattc tgtgagaaat
     2161 tatcagtaga aaccatcgca atcggcaact ctccagcatt aaatctgcta tataacaagg
     2221 atgttacaat actcatcgta tgttgaggat tgctaggtcc agatttgata tcagctttga
     2281 ctaccgaaaa gaattgccct ttagaatctt ttaaactgta acctttttca gtaatagtaa
     2341 acgttgtaaa ctgtaattta ggatcttcaa aatatttaac cactctttga tagtccgcta
     2401 tattcttcgg attgcaatat aaactatcag ccgttactgc caaaagtctt tttttgagtt
     2461 caccatctcc actcataaca atttccaaaa tgtcattgtt atagtcatga taagcttttt
     2521 ccactacttc ttcatcaaat gtttcacaca caactactcc tgtttctaat tcattttgat
     2581 ctgctaagca ttgagcaatt tctgcatgaa atcctcgata aagatttcct ccaccaaaat
     2641 gaagccatac tggatgttgc tggccttctt gcttaacttc tttgacatca aaacacggca
     2701 gtagaatctg catttcattg aattcttcga tagaattttg ccaattttta atcgaaacca
     2761 taattaacct cctcaaactg atatgttagt tttgatacat tttatatttt aaaacccatt
     2821 gtaaccgttg tcaatataaa aagggaataa acttgctttt ttctaccata tcagaatgat
     2881 tgtatttttt attcagaaaa ataaaatact ccttcttttt ggactgattt tatcgaaact
     2941 tattttttct ttttttcatg tattctttta tttttataac tagtgtatta cttcaaaatt
     3001 tgatattata tggcatgaac agaattaaaa tatcagttaa aataaaagtt aaggagcatt
     3061 gtgtatgaca attaaaacta gtctccaaaa tcaagcttac caatctattc gccgacaaat
     3121 tatctatgct gacttagaac ctggaaaaaa agtatcagaa aaaaaattag aagaaacact
     3181 ttctattggt cgtacaccaa tacgtgaagc actgattcaa ctccgacaac aaggtcttgt
     3241 tgatacaatt cctcaaagcg gaaattatat ctcattaatt gatttagatt cggccaaaaa
     3301 tgctcgattt gtcagagaac atttggaacg acaaattatg ttagagtgtt gtgccaaaat
     3361 gaataaccaa aaaaaacgga ttttagaaac tataatttca gaacaagaaa aagctgttag
     3421 tcaaaaaaat gctcgtagtt tttttcataa tgataattta ttccataaag cttgttttga
     3481 aattgcagag cgagaagaag tatggcaatg gttagaaaat aacaatacac acttagaacg
     3541 atttcgatgg ctacgagtaa aaacggaagg attaaagtgg gaaaaaatta tggaacaaca
     3601 ttatcaacta tttgaggcat taacaaaaca agatccagaa gaagctaact ttctaacatc
     3661 gttgcatctt catttaatgc ttaatgagca aaatattgtt ttagctactc atccaaaata
     3721 tttcaaaaat atataacttt taactctttt taaattaaat ggttgttctg atcagaaaaa
     3781 tatcgcttgt tttcttatta tgtaatatat ttcataaact attctgcata acaactattg
     3841 tttgtacttt ttacattgga taactaatta tgactgctga taacttttga tattaaacta
     3901 gtatctccaa tacaaataaa aaatagatat cttgttcatc aaaattagtt cgtggatact
     3961 taccttcatt tacatcattc agcggtttcc cattttcttt tattctatta tttcattttc
     4021 taatagactt ggcttcattt cgcaatactt tttttcaata ggcatcaaat tggtgttgtt
     4081 tagatattta gttgtagttt tgtgacatga taagtatgct cctttttctc ttttccacta
     4141 atacaacgat caaagggtgc ttttttcaaa aaactagaaa aatcaaaata agattcgtat
     4201 tttgattcta tatatcctgt ttcaactaca tcttatattt cacaatagaa taaatagcct
     4261 tttgcatagc tgcttaactt ataagaaatt gcaatttact tcttcaaagt gaaaacgaat
     4321 atgagtaaaa taaaattatt cttcttacag ataattaaaa atagcgcgta acaaaaatcg
     4381 gcattcaatc acataattag gattgatgcc gattacttat attctacgta tagttttagt
     4441 attcttattt tttatcacca gtaaccaatt gagaacagcc ctaaagcaga atagtctttt
     4501 atctcaaaac gcttaatttc aggcttagga atatgaataa tcttttgagt atattctttc
     4561 tcttttaatc ttactgaaga aataccactg cctatctttt ttacaaatat ttcatttggt
     4621 gtacagacta ataaaacaat atttgtaatc aatccttgca ctaaagaatt aaaaggaaga
     4681 ctatttaaaa cagggtgtgc ataactataa catgtgaagt agttattttg aactttaact
     4741 tttaaaaact ttaaaaataa tcttatttgt tcttctaaac aatcatctat actcatataa
     4801 tcactccact aattaatctc cccaaaaaga cacagcatta agagatatac caacacaaca
     4861 gtgcaaataa ctctacatct tccttcgcaa ccttatttca ataaaccata aaaattattt
     4921 tttaatagaa actgaaaatt aaaactagaa aaagtagttt taccgaatgt aagagcatca
     4981 tcaccatcaa tatagaaata cattcttttc cagttacatt taatttttaa acaaaattct
     5041 ccccaaaaag gaactttttc tagtgaaaac ttggtaatct ctttgtaatt aattcttgtt
     5101 aaagaataat taaacacttc atttttactt gttatttttt cattgactat aactagttca
     5161 tctggtaaaa aaattaacca acaaacatcg acaaacagta aatgatataa tccatttcca
     5221 cctccaagca tattcaatac tggtgaacat gccttagaaa cacgaatata gttatggttt
     5281 aaatagatat tttctttaaa cattgcttgt ttaaaagcca tatgctcttg ttctaaactt
     5341 ttcataaact tttactctaa tgcacagcta gcagcagctg ctgcaattcc tgctacaata
     5401 tttaccttag ctaactcttt agctgcagct tttcctaatt gtttttctgc aatttttaat
     5461 aataaatccg cagctttttc aaaattaaaa gcttttaatg cttcaataaa atctccctgc
     5521 gtacctatag cccaagccac tcctcctcca ggaagagaat taatggctac acatccagca
     5581 tatcgtttcc aatcaacttt ctccattcta ggaacaataa tatgttcata aaagactctt
     5641 gctgctcttc cttgttcgtt atcttgactg attcgttcac gaatagcacc aaaatccttt
     5701 atatggtata caccatgttc gtctaaaaaa ccaactgtat caaaataaaa agttaattca
     5761 tctactaatt tattctttat ttctaaatca actgtattca ctttttctgt ggcatacaca
     5821 cttgttccag tactaacaaa agtacttaaa cctaataaga aaacacctaa aacaccaaat
     5881 attttaatta ttcttttcat aatttctcct ccataaaaaa taagttactt tttaaatatc
     5941 ttgtttatga attcattccc caaaggcctt ttaagattga tacagcagtc cgttcacttc
     6001 ttttagactt gtcatacaag tcttttaaat gatcccatat cagactagtt tgtctatcta
     6061 gcttcaatcc attaaacgct aatgaacggt tcattttttc tattacttta gataaagcta
     6121 cagaaatttt tataccttca caacgcgcat cttggatttc aataatagta tcatcaatta
     6181 gtttttgaat ttcttgccta tcaacatatt caatcttaga aagagaatct tttaaagcta
     6241 ctaatgattc aacgatttct tttttctctt cagacatttt cttcctcctt ctagtgaccc
     6301 gtaaagccat gtagagcaga gtccattgaa ccagtaatta cactatctac aacgccattc
     6361 caatttactc tacattttcc atttttcaga tttgtcggtc catacggata gcctttttga
     6421 cattcaatgt tcggattata ccagatagga ttataccatt cagccgcaga agcagattca
     6481 gtcgatacaa acaatcccac accaacaaat ccaatacaca tcacactata gccaattagt
     6541 tttttcatct cgtatccatc tcctaaaaaa tagaatagtt cttatagtta ttcataagac
     6601 atattttttc cgtttttgtt ttatcctttc tgtcctataa caactttttt caagtaaaga
     6661 atgacatagt ttttcttaaa aaaacagtct gtttttttct atttcttcgg tgtataataa
     6721 atatgagtgt tcatttttta ttttaatacg cactccgtac ataataaatc ttgatcgcat
     6781 caatcttttg agcttcttga tctactttca attgaagtaa tacaaattga gtaaccttat
     6841 tcattgtttc ttctccaaat aacaaatatt gatccggatt ctctatatct tgtgtcacct
     6901 ggtaaagttt cccagttgtt ttcatttgta catgcgggtc tacatcaata ctattgtctt
     6961 taatacaacg atctgtcata tagtccctca cagcttgatt gcgtttataa acatctgtga
     7021 aattactcca ttttctagca aaatctttta agaaattttt tgtcatttca tctatttgca
     7081 tttgttgcgc tgtctcgtct tctaatgaac caatttgact gttactttca gtactttgaa
     7141 gagttccact tgtttctttt actgcttcga ttgtttcttc tgtcgttctc aattgtgttt
     7201 tttgtttttc agaagaaaac caatgacaac cagtaagacc tatcaaacat aaccaactaa
     7261 atactaaaat tatccctttt ttcacgtttc tagtcactgc ctttcttatt tcaccttacg
     7321 aaccagacta cgaatttttg tttgattgta cgtgcgttga taccgagcca taatccgtcc
     7381 ttgctcggca ttctgttcca cactagagaa atgttgtccg ccatatgaaa catctgttat
     7441 aattccggtg tgaccataga ttccaggaga caatgcacca cctgcttgcc aattcaccac
     7501 atctcctgct tgtaaatcac ttggttttgg gttcatgatt acttgccaac cataggttgt
     7561 ccagttataa tcttccccta ttaacatcgc aaacatgtgt ccagaaccca ttaactgtgg
     7621 gccacctaat tgagatacat accatgccgt accaccataa cattccccat tatttacgga
     7681 tcgtccaatg atccgatcca aaaccttcgc attgccttta ctttttcctg caataagcga
     7741 agtttttttt gttggtaggc tattccaatg cttgatcgca aaagtatcat attccgttaa
     7801 gttataggac gttatgatac tcattgctcc tcgataatac ggactccctt cggtaatacc
     7861 tgctgccgca tagcctccac gacctagaat caataaacaa cttccaggat ctttattgcc
     7921 cacacattga ttaaagttgc tttggctcgc caccataaag ccataatagt cataacaagc
     7981 ttttaagttc ggaaacttca tatagaaacc accttcagaa ccaccaattc cacgtgcaga
     8041 accttgtggg tagggacaac caggaaacca ggtaatccca aaaaagttcg tatcgtttct
     8101 tccagattgt gactgtccat aagctgattc atagcctaat tgagaaagaa tcacactcgg
     8161 taataactga tactttacag ctgcaccaac tgctgcttgc gcatgttcat ctgtgattgg
     8221 accacgtcct ttaatctctg aaaaaatcgg taatccttcg gtatattccc cattaaaagc
     8281 gacagctaga cctgtagctt ctcctccatg ctcagaaagt tctcctgaaa aaaagaatgg
     8341 caatagaaaa aagggaagaa taaagaaaag aagacaacct agacaccctt tcttcatttc
     8401 ttcctcatcc tttcttcgat aatggttttt ggactgttcg tccttttggt aaagtaaaat
     8461 cagttcctgg ttttgcgtcc aaaatcggca gtgttttagg atccttttct attttttccg
     8521 attgctctgt tggcttatct aaagaagaaa atgcaggttg taacgatttt ggtgcggaaa
     8581 tcgacggttt actttcagac gaacgttgcc ccggttgttg cacagaacga tttcctgata
     8641 gagtggctac cgacgaatta ggaacagagt attggttcaa taactgctgc attgctggat
     8701 aactcccatt tttcgcctga tttttcactt ggcgaatctg ttgtgaaaga gaaccagcag
     8761 ctgttaattg tggcacgggt acttttccag aaggcaacgg aatcgattga ccaacaaaag
     8821 cgataccttt atttaacaat ggttttcttt gattattccc ttgttgctta ctcaattgtg
     8881 ccaatgattg tacctgttgt tttggtctta ctgaattcat ggacgaattt ggaatcaaac
     8941 catttgaaag accagaattc cactctgttt tcgatttggt agaagacatt tcaggctcta
     9001 ccccatgata acgaacatga cgaccactat aaggcaaggc ttgatttgaa cgcccaccta
     9061 gttcaaaggg attaaccact tgcctccctt ttaccgattc ttgtggtgta cgtttttgtt
     9121 gaaacttttg aaatccatgt atcgctgcag aagcgagtgg attcgttgct cgatacacat
     9181 tccctgctaa tcctgcacct ttgattgcca aattttgtcc agcagttgat agttgaccag
     9241 gcagttgttt catttgagac aaagaatgac ttgctatgtt tttcgtgttg tttatagttt
     9301 gatctgcagc tcctaaccct agtttcttta ataaatcttt ccgttttaca atgagtaaaa
     9361 ttgataggag tgctttgaca aacatatttc ctaaaaaacc aaaaacagta ttcattggaa
     9421 ttaaatcgtc tactatgtta tagatcaaaa atgccaccaa aataatcaca ctgtaaaaag
     9481 atttttgaaa catcaagccc aaaaaggact ttaaggtatt catgagcata taatcaaata
     9541 ctggaacaaa agaagcgagt aatgaaaaag gaatcacaag taataaacac aacaccaaca
     9601 tttgaaagat aaaacgaatc atgccaatca ctacaagtgg taatccaata cttagattaa
     9661 gcaatggcac catagaacca acgactgctt tataaacagc tttagttggt tgaatataga
     9721 cacgataagc cttctttttc cctctatctt ctcctgcagc agtggtcact tttgtctcaa
     9781 tatcagataa ttcttcactt gacgcttcct tggctagaaa ttcttgtggt tcaatctctg
     9841 cttgatacaa ttcttctaaa tttgttgtcc cataatttaa caatatatac ggatcaacaa
     9901 cagccgcttt ataataaagt tggcgcactt tttgaatggc ttccttttgt gtcgttggca
     9961 ctaaaacacc attgacatct tttgtcgcca attcatctag actatttgta gcagaaaaaa
    10021 taaagccttc tacctccacg gacaaatcat ttaacccttt ggtaaaagct tctcctttac
    10081 taggtacgtt actaccatag ccaaaccaaa ccattgaaaa aatgacaacg aagagaaatc
    10141 gaataaacac catttttgcg taatgtttcc ctctaaatat acgaagagta aatagatata
    10201 acacatacaa gacgacaatc cccgcaccaa taggatcgta tatttttgaa taaatagtat
    10261 ccgaaaaagt gaaaaactgg tgaattaact cgttcattgc agctccttca tagagcttct
    10321 caatgacaaa atcaaggcct tgccaaatca atttacttaa actaaagaac atattcgtca
    10381 tcatttttag aaaatctgtg ccatttgccc caaataacat tttgcctaat gaaaattcac
    10441 tatcagataa ataagaagaa aaggtatcaa tatgaaattt cccaatctca tagatcgatt
    10501 gatccacctg cttttctgcc gcatacacca atccaccaac aaaaagcagt ccgaatccaa
    10561 tcgttaaaaa aaacaaaacg caccatttct tttccttatg ctttatataa gccattgttt
    10621 cacctcattt ctattgcatg attaacgtat cctgttcttc tacttgagag tgacttgttt
    10681 tttccgttgt ttgtaatgca gcggtcattt cttcaaacaa actgtgtaca ttgagttttc
    10741 ctacacgtcc atagggatct aacatccaac actgtccttt aatcatgtgg ctcatttcag
    10801 ctaagttcgc ttcatttact tccaaacgta aatgattcaa aatcttttct cgctcactgt
    10861 cttcatcaaa agcaaagacg acaccaaaat tccctttttc tttatctgaa cctaagtcac
    10921 caataaattg tgtatctaac actaattgat tcatctggga acgccccaca cgtgccattg
    10981 ctgcaataat actacgtcct gcgttcgaat tattaaatac ccatgcttct gtaaaataaa
    11041 tcgctgtttt cttactacta tctcgttttc caaacatttc acaaaaacga cctaaactaa
    11101 tcatcaaaca caaagacttt cgatccgcat ctgtatatag ttctggtcgg acattgtcat
    11161 ttggtaattt caaatcttgg atctctaaaa tcgttgtttt ggcattaaag tctaatcccg
    11221 ggttttctcc ataagaaaat cctaaacgta aaatcgaatc ttctaccgtc aagcgtaaaa
    11281 actcaccata ttctcgaacc tctttttgtt ccatttgttc taaatagtcg accacatgca
    11341 tcaagccaac ttgttgtccg gcttcttttt gaactaaaac ttcttggatt ccctttaata
    11401 ccgccccttt taaaaggtga ttggtaccta acggacttaa ctcatcaatc atatcctggg
    11461 ctacttgttt cgcatctact cgggataaac aaacaattgg atctaataca ccataattac
    11521 ggggatttgt agcatctaac gtgacataac tcattttttg caaatgttct acaaacaaag
    11581 ggtaatgttt ctgataatac gggtcttgaa tgagtttcgt aaaccatttg cgcttttctc
    11641 ctttgggatc cacaaataaa ctttgtacat tcataaacga actatacaaa aagagcaagc
    11701 caactaaaaa ggtcttccct ttaccggttt ttccagttac tgctacatga ggcgcatcaa
    11761 acaacgcacc tttgattcct tccgcaatgg ctagaagatt caaaaagaca aaacgatttg
    11821 acgcataaat taattcttct aatggtgttt tttctcctcg agaaccacca tcccctaatg
    11881 tatcttgccg accaatatac cagccggatt ccatacctaa ttctgatact gctgaaaaca
    11941 accattcgcc aactgcttct acagttgttc ggtgcttcca atgtaactgc cgtcccaatg
    12001 gttgccctaa taaacattta tagaacaatt ctcgttgatc attttttgca cggtggatat
    12061 ggataatcgt atgaagttgt tgaataaccg ttgcactatt ttgacgaact tcttcaaccg
    12121 tttgaccgta tacaataaaa catgcgatcc aatcgacgac aggttgccca ttatctactc
    12181 gttgctttaa atgttttact aatcctcgaa cagttaataa gcgttcacta ggttcttcat
    12241 cattttgaac caattcctta tgctctgttt tgaaccgttc cgatagccaa ttcagtttta
    12301 aaccaatacc tccctgtcct ttcaagcgtg gatagtgaat tttcattcgc aattctgctg
    12361 ggaaagaaag atcctgagca aattgaaata gatcacaatt tctcatattt tcaggtgttt
    12421 ccccaatagg caacaatgct aaataactac tccctaactc atcttctaat tgaagaaggc
    12481 ctttatgttc cttcggtata cgtacatacg ttccttgatt gtctttcagt acttcccaat
    12541 tattttgttc ttctactttg tgagccattc ctcgaatata ttgcagacga ttgagataca
    12601 acagctcttt ttttactaag ggacgaatag aaaagctata aagtaattgt gtcacttctt
    12661 ttacataagg atcactttca gaaaacaaag tttccaaatc atctacttct aatccaaata
    12721 agcgtgctaa acttcctgct aaatctaacc agattagatt tattacatca tgaaaactct
    12781 ccaccgttgc tttttctttg actttgattc ctaaaataaa tgaaggacga tagacttgac
    12841 cttctcgttc caacaatgtc actgtttctt ttgcataata cgcaccaatt gcttgactat
    12901 cgggagaaaa tccctttcct aatgtgtcaa acttcgtccg taaattcatt gttcgtggat
    12961 acatcaccaa ctccacatct tcataatctg ctaaaagcaa cagtaaacga gccatcattt
    13021 cttttatttc ctgtgtcttt tttggtgtgt tttttgaaat tgttcgtgga aaaacatgat
    13081 agtaggccca gatacaatcc tctccattta acaaacaatt tttcttgaat gcttttactg
    13141 gttcttttac aagcaccaat gaatttcacc tcccaataaa aaaggaacaa ccagttgatt
    13201 gtcccttttt ctaatcctct aaataaacat acttattcac aaaaagtaat tcttccaatg
    13261 cattgtttga taccttgtcc cagttataat acacacaatc accattcatc atacgaatca
    13321 tataacaaaa ccaatcccat aaataaaaat gcactttttt tccatcaggt tttagttttg
    13381 ccagtgctaa cacacataaa taggggagtc ctatataaaa aacaactcct gctggtggaa
    13441 aaaaagaaat gacccaacca ataaatgaac gtaaaaataa atattcaaag attacgacca
    13501 acaaaaaagt tgctgcattg acta
//
LOCUS       DAZKCW010000063        13328 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000063 DAZKCW010000000
VERSION     DAZKCW010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.065"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            292..2031
                     /gene="yfcC"
                     /locus_tag="ACG84Z_002202"
     CDS             292..2031
                     /gene="yfcC"
                     /locus_tag="ACG84Z_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFP9163009.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2188..3372
                     /gene="iadA"
                     /locus_tag="ACG84Z_002203"
     CDS             2188..3372
                     /gene="iadA"
                     /locus_tag="ACG84Z_002203"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFP9163010.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3483..3686
                     /locus_tag="ACG84Z_002204"
     CDS             3483..3686
                     /locus_tag="ACG84Z_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFP9163011.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3787..4449)
                     /locus_tag="ACG84Z_002205"
     CDS             complement(3787..4449)
                     /locus_tag="ACG84Z_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163012.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4462..5964)
                     /locus_tag="ACG84Z_002206"
     CDS             complement(4462..5964)
                     /locus_tag="ACG84Z_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9163013.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVTVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6512..8191
                     /locus_tag="ACG84Z_002207"
     CDS             6512..8191
                     /locus_tag="ACG84Z_002207"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFP9163014.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8318..8797
                     /locus_tag="ACG84Z_002208"
     CDS             8318..8797
                     /locus_tag="ACG84Z_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFP9163015.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            9016..9696
                     /locus_tag="ACG84Z_002209"
     CDS             9016..9696
                     /locus_tag="ACG84Z_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFP9163016.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9704..11035
                     /locus_tag="ACG84Z_002210"
     CDS             9704..11035
                     /locus_tag="ACG84Z_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFP9163017.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            11050..12012
                     /locus_tag="ACG84Z_002211"
     CDS             11050..12012
                     /locus_tag="ACG84Z_002211"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFP9163018.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            12123..12461
                     /locus_tag="ACG84Z_002212"
     CDS             12123..12461
                     /locus_tag="ACG84Z_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFP9163019.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12540..13247
                     /locus_tag="ACG84Z_002213"
     CDS             12540..13247
                     /locus_tag="ACG84Z_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFP9163020.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4277 a         2333 c         2906 g         3812 t
ORIGIN      
        1 tttttgcaat gaaattcaat ttttcaatga ttgtaaaatg aaaaaaacag gacgagattt
       61 tctctaatct aaaaataaaa aaagaatttt aaggaaaaac agagaaataa aatacttaat
      121 ataaatggaa agagaaaaaa ataatcatac ataggagaaa aaaaacaaaa tagaaaaaag
      181 tgattttcta ataaattatt catgtggaaa tgtcattttt actgtataat tcatttgatt
      241 atccattttt tattcatcaa aattactgaa aaaagaaagg aagaaataaa tttgaagaaa
      301 acaaattctt caggaaaacc gaaacgcgac ttcactaaat tatcgacacc ccatacgtat
      361 gtcattattt ttggtgtagt catctttgca tggatactga cttttgtcgt tccagcagga
      421 aagttcagca cgcaagatat tgaatacaaa gatgcaaatg gcgaaacaag tactcgtact
      481 gttttacgtc aagattcctt ccgttatgct tacgagctgg ataagtcgta tgtgtttgat
      541 caattagaag aactgcaaga tcatccagca gaacgtgaaa aactggatgt tccggaaaaa
      601 ggattggaaa aagtcattgc tgacggagaa aaaaatctta cgcaggaaaa actagatgaa
      661 atctccttga cagatgatgt gctttacgat cagtacggcg aaaatatcta tgatacttct
      721 aaaaaattgc ataaaacagc caaaatatgg ggaacagatg attttggcgg ctttggtttc
      781 ttaaattttg tttttgaagg actagtatct ggagataagt atggatctgc tgtagggatc
      841 gctgcattga tccttgttgt tggaggtgct tttggtatta ttatgcgtac cggagcgatc
      901 gacgcaggta tctatgcgtt tatcagtaaa actaagggac tggagcgttt agctttaccg
      961 ctattattct ttgctttttc attcggtggc gctacattcg ggatggcaga agaggtaatt
     1021 ccattctcaa tggtgatggt tccatttgtc attgcgttag gatatgactc gatcgtagca
     1081 gtaaccgtga cttatgtcgc atctcaagtc ggaaatgcga cctcttggat gagcccgttt
     1141 agcgtagcgg tggctcaagg gattgctgga atccccgtgt tgtctggtgc gacattccga
     1201 ttgattatgt gggtagttgt tactgcatta gccgctggtt atatgatgat atatgcagaa
     1261 aaaatccgta aaaaaccaga aagttcgttg acttacaaat cagatgatta tttccgttct
     1321 catatcaaaa agacatctga tgaaaataaa aaattcatgc ttgggcataa attgatctta
     1381 ttagagatgt tagttgtcct tgtctggatc gtttggggcg tgactcaaaa aggctattac
     1441 attccagaaa tcgcttctca attctttgtg atgggattag ttgctggaat cattgctgtt
     1501 cttttcaaat tagatggaat gaaagtcaat gacatcgctt cttctttcca atctggtgca
     1561 gctgatttag ctggtacagc aatcgtagta ggtatggcca aagggattct tcttgtcttg
     1621 ggaggatctg atgcatctgt tccttcagct ttgaatacga ttttgcatgg gatcgggacg
     1681 gcgttgaccg gtgttccagc tgtcattggt gcttgggcga tgtacatctt ccaaagtttg
     1741 ttcaacttgg ttgttacatc aaattcagga caagcagctt tgactatgcc aatcatggct
     1801 ccactggcag atttagtagg tgtatccaga caagtagcag ttcttgctta tcagcttggt
     1861 tcaggtttta tggacgcttt tacacccgta tcagccagct tgattggtgt gctaggtgtt
     1921 gcacggatcg aatgggcaaa atgggcaaga ttccaaatca agatgcaagg attcctgttt
     1981 gttttaggaa ctattttcat catgattgcc attgcaatag gtctgcagta gtactggaga
     2041 cctgtaaata aaaaagtaat ccaaacagta gataaggact ccaagaaccg tcattttacg
     2101 gtaaaatcaa aggagtaaag atcctatcgt ttggattatt ttttaagatc ctatcatcag
     2161 ttatacttaa agaaagagga aaaatgtatg aaaatcattc gacaaattga agtgtttgca
     2221 ccagattact taggaaaaat ggatgtactg attgccggtg ggaagatttt ggctgtagaa
     2281 gaacagctag aaggcggcta cgaaggagtg gaagtagaag aactttcagg tgagggaaaa
     2341 gtactaaccc cgggtttcat tgactgtcat ttccatattt taggtggagg aggagaaggc
     2401 ggttatcaaa atcgaacgcc agaagtcaca ttgagccaat tgactacagc tggtgtaacg
     2461 acagttgtcg gttgtttggg aacagacgga gaaggtagag atatgactgc gttgatcagc
     2521 aaagcgaaag gtctggaagc agaaggaatc tccacttatg tatacgaagg ttcgtaccga
     2581 ttgccggtaa aaacagtaac agattctatc atcaaagact ttttgacaat tgataaaatt
     2641 atcggaatcg gagaaatcgc agtatccgat caccgttctt ctcagccaag ttttgaagag
     2701 ttcgctcgtg cagtagcaga tgctcgtgta ggaggcatgt tatccggaaa agctgggatc
     2761 atcaatgtcc acttaggcgg aggaaaaaga aagctagagc tattgacacg aatcgtagaa
     2821 gaaacagaaa ttccgatcac acaatttttg cctactcatg caaatcgcac accagaatta
     2881 tttgaagctt gcgtggcatt tgccaaacgt ggtggcacga ttgacttcac tgctagcgaa
     2941 gatcctgatt tttgggagaa gacagatggt gaagttcgct tcagcaaagc actgaaacga
     3001 ttgatcgagg aagatgtttc tttagataat ttcacgatga cctcagatgg acaaggaagc
     3061 ttgccttatt ttgatgaaaa caatcatttc ctagggttag gagtaggaag tgccaaggca
     3121 ttgctagtag ggatcaaaga agctgtgcaa aaagaaagta tccctttgga aatcgcctta
     3181 cgagctataa ccagtaatcc agcacgtata ttgaaattgg ataaaaaagg aaaaatcgaa
     3241 attggtgctg atgcagatct gtgtatcttg gataaagaaa cgcttgatat tgatacagtt
     3301 atcgctaaag gagaaataat ggtccaagaa aaagaagtca aagtatgggg gactttcgaa
     3361 aaaagttttt aatcaacagc tctaactatc ttttttagaa aacgagcgtt ctgtttgtct
     3421 gtatctgttg ttgatgttac cctgaaggta gatcaataaa caaactaaga ggaggaagca
     3481 caatggcaga tttaaaagga cgttctaaag atatgaaaga taaagtagtc ggtgaaggaa
     3541 aagaagcata cggcaaagca acagacgaca agagcaaaga aacagaaggg aaagcacaat
     3601 cactaggtgc tgacatcaaa gaaaaagctc gaaatttagg cgacgaagtc aaagacaagt
     3661 tttctcgaaa agacgaaaaa aaataaaaac cacttattac taattgaatc aagcaaataa
     3721 aaaatccgaa ccatatctgc gagacagata tggttcggat tttttatttg atcattatcc
     3781 tgttttttaa acttcgattt tttgaaattt tttatttttt agttcaaaga cttcatcaca
     3841 gctttttgct acttcaatct catgagtcac gatgataata cagcgatttt gttcatgggc
     3901 gatttcttgg aaaagtttga cgatatcttg tgaagttgtt tcatctagat ttccagtagg
     3961 ctcatccgct acgattagtt gatgttcaca gcagatagca cgaacgatag cgactcgctg
     4021 ctgctgacct cccgaaagtt tggtcacctg tttttttgct aatatttcat caattcctac
     4081 acgagccagt cgatctaaag caacttgtcg ataattctct tgcttggtct tagtgatttc
     4141 cattgctgct atgacgttgt ctagagccga taaataagga agcaagttgt aagcttggaa
     4201 aataatcgag acatcatttt tacgataact tcttaacccg attttgttca gtgaacgatc
     4261 ttgatagtat acctttcctt cttttggtgc atctagtcca gaaataagcg aaagaaaagt
     4321 cgtttttcca gaaccacttg ctcctaaaat agcgtacatt tttccagctt cgaaattcag
     4381 ttctacatct ttataaagcg catcttgcgg atcttgatac caaaatccca attgttctgt
     4441 ccgtaacatc aaattcctcc tttagtttaa taggattttt cttgggttta atcttaatat
     4501 ccctatagaa gctaaaaaga cagaaaacag actgattcca aatgctactc cggctaatag
     4561 tcccaattgt gcaggtttga cattgatttc caattcgctg acttgatcag aaacagcaaa
     4621 tggattattc gtggttcctt gttgaccatc gcgttgaccg ccttgttctt gtctgttacc
     4681 tggcatttgt ccaccgccag gagcttgctg gttttgtgtc gtggtttctg tctgttggtc
     4741 aagtagctgc tgtcccacgg cattcgcgac gacgtttccg ctaagcgaag caactcctaa
     4801 tgcaagaatc atacaaatag ccacttcggt aaacaattgg agaatgattt tacttctgga
     4861 ttctcctaaa gatagcaaga cgcctaactc atgccgacgc tcccgaatgg taatcataat
     4921 gatcagagta agtatgataa taccggctac agtcactagt aaaacaacat ttttagaaaa
     4981 acttgccacg ttgtttaaag gttccaacat tgactgatac atggaatcat ttgattgtaa
     5041 gctaaatgta tctgtgtcga tcagcttctc agcttctttg agaaactcat ccattttatc
     5101 tggatcagat agagtgtaaa tagcagaatc tatcgtgtta tcgtcagatg tcccatttag
     5161 ttcatttgca aaagtgtaag aagtgtaaag tgtattcgac ggattcatga agttgaattt
     5221 catacccata ctgccgcttg tttcgctgga ttcataaatt cctttgatcg tcatttcata
     5281 agtggtatct tcatcttcag tactcgtgat tgtgaaagta tctccgactg ccaggtcatt
     5341 tgtttctgct agagtagaat caatgactac attgtttgtg cctttgtcgc tgtcatctat
     5401 tccttcacca tccgtgattt ttgctgttcc atcagaaaaa ttactatttt gtgcagttgc
     5461 tgacacacca ctgatttgaa agtctgcttg agtcatttgc ggattcccgc ccattcctcc
     5521 agcaggttca ccgcctgcat cagtagtttc tgaactgtct tcacttgaat cagaactagt
     5581 gatggcagtt attccatctt ttgccatagc tgaggcggaa ctttcaaagg aataactctt
     5641 tacattatct aattcagcta ttttttccgc gtccgttaag gaaactggtg taagagaaaa
     5701 actgcctgga tctggacgtt cttcagtggt agaaccgctt gaagaagttt gttcctgttt
     5761 tttaaatgaa gcttctcgat tggcacttaa agtcactgtt gctccaactt ctttttgtgc
     5821 ttgattcgct gcttcttctg cagcgcttcg aatcgtgagg ccagctagca caaaaataag
     5881 aatggctgtg aacacggcaa acaataacaa tgaacgtccc cattttactt ttgtactttt
     5941 ccatgcacgt ttcataaaat tcatattttg catccctcct agtagatgca tttgataata
     6001 gacaacctat cttaaagcta gcttaaatct tatgctgttt gcacaccatc aacatgaggt
     6061 tctgtatata taaaaagtca ctatagttat tgcaaaaaat gtggtaaaat gaaaaaagta
     6121 tgtttcaaac cgacgaagaa gaaatgaaag aggaatagca aaagaaatcc tagatgctac
     6181 agagggattt ttacgtgcat agttgttcta acaattgctg atactagcga tttagtttat
     6241 ttgttgtata ataatgggga acagctgaat acttatataa gtattctggc tatagcgttt
     6301 cgcaaaagat ccattttgtt aatgaagtat atccaaaata aaatgcccat ccaactgtca
     6361 gaacgcggat gtgctggtaa ttttcctgct gattctccat aagttgagaa atagtgattt
     6421 tgcatatgct tcattggaat ggctcatata tttagataaa gaagaaaatc gacatcttta
     6481 aacttggatg tcataagaag aggtgaagtt tgtgagtacc attaaaatta tcccattagg
     6541 cggcgttcgt gaaaatggaa aaaacatgta tgtcgcagaa gtgggcgagg atatttttat
     6601 tttagattgt gggctaaaat atcctgaaaa tgagttgttg gggatcgacg tcgtaatccc
     6661 tgattttacg tatttagaag aaaacattga tcgtgtagct ggtgtctttt taacacatgg
     6721 acatgcagat gcgatcgggg cacttcctta cttgttgtca aaaatttctg taccagtatt
     6781 cgggacagag ttgacgatcg agttagcaaa attgaatgtc agtcgtaatg aagcagccaa
     6841 aggatttaag gatttccatg tggtagatga gcatacagaa atagactttg gtgaaacagt
     6901 agtgagcttt ttccgtacca ctcatacgat accagattca gtggggatca atctgaaaac
     6961 aaaagaaggt agtatcgttt atacgggaga ttttaaattt gaccaaacgg ctatcccaat
     7021 gtatcaaaca gattatgcac gattggcgga aatcggcaaa gaaggagtct tagccttact
     7081 aagtgaatcg gcaaatgcag aaaatcctca gcctgtagct tctgaagccc aaatagcaga
     7141 tgaagtattt gatacgatca aatattggga agggcgtatc atcgtcgctt gtgtagcaag
     7201 taatttgcaa cgagtgcaac aagtattgga tgcagcagaa aaagcacaac gaaaagttgt
     7261 cttgactggt caagatttcg aacgaattat tcgcacagcg atgcgtttag aaaaacttca
     7321 attaccaagt gaagatctgc ttgttacgtt gaaagacatg aaaaactatg atccagaaga
     7381 actgatcatt ttagaaactg gccgaatggg tgaacccatc aagtctctgc aaaaaatggc
     7441 aaacggtaca caccgtaatg tcaagattga agaaggagat ttggtttata tcactactac
     7501 gccaagcatc gcgatggaaa ccatcgtggc gaaaacggaa gatatcattt atcgagctgg
     7561 tggaacagtg aagttgatct ctgagaatat gcgcgtttct ggccatgcca atcctaatga
     7621 cttgcaatta atgatcaatt tgatgaaacc aacatatttt gtgccagttc aaggagagta
     7681 tcgtgaatta gctgctcatg cagatttggc tcatgcagta gggatgccat acaaaaatat
     7741 ctatattact ggacgcggag acgtgctgga atataagaac aagcgtatga gtgttgcagg
     7801 aactacaagt gcagaaaatg taatgattga tggattaggc ataggtgata tcggaaacat
     7861 tgttttacgt gatcgaaaaa tcttgtcaga agacgggatt ttcgtagcgg ttgtcactat
     7921 cagtcggcga gaaaagaaaa tcatttcaaa acctcaaatt acttcacggg gattcgttta
     7981 cgtaaaagct agccgtgatc tgatgaaaga aagcagcaat atgattgaaa caatcgttga
     8041 gaaacattta gaaagcaatg attttgagtg gagcaaatta aagcaagaca tccgagatca
     8101 attaggccgt tacttatttg aacaaacaaa acgccgccca gtgatcttgc cagtcattat
     8161 ggaagctact caacgtcgaa ataaaaaata aacaaaaaga gtaagatgaa cctctctata
     8221 gagtgctcgt cttgctcttt ttttgcgaaa aacaaataat ttttgaatac agcatccctc
     8281 gctttataat aaacgataga ataaagggag tgaatcaatg atgagtcaaa caaaagtcga
     8341 acgttattta gaagaacaaa agatcagcta tcaaccactt gattttagtc atgtggtaga
     8401 agaatctttc acagaagaac tacaaaaaag agggattgat ccagctttga tatgtaaaac
     8461 tctcgtagtg aaaggaaaca aaactggggt gatcatcgca ttgattcctt tgaacgatca
     8521 cttagattac aaaaaaacga gacaagtgac gaaagatcgt aaagttggtt ttcctggaat
     8581 ggattttgta ttaatgcata caggatatcc ccacggagca aacaccccta ttggaataaa
     8641 actcgcacat cctgattatt gttttttagc agacagttct ttaaaagaaa aagaagaagt
     8701 aattgtgtca agcggtgaaa tcgggagaag ccttcggata aaagtagccg atttagaaaa
     8761 gatcgtccat cctatttacg ctgatttaat tagttaaggg acgagaagag aagctaagca
     8821 gagcagagac ctcaaacttg agattatatc tgcttggtac ttggtgcatc ctgtattatc
     8881 tgttacaatt gctttgtaca tactgtacta tcaatccaat gaaaatatat ttagcagcta
     8941 tattttttca ttgatgtgca agtgatgaaa tcgtttttaa taaaaaagat acagagaaaa
     9001 cgcgaggtgt aaaatatgaa aattacgtat catggacatt cctgtttaac aattgaaatg
     9061 gaaaatggcc aacgcgtgat gattgacccg tttattacag gaaatccatt gacagactta
     9121 actgcagaag aagtaaagac agattggttg ctgattactc atggtcatag tgaccacata
     9181 ggagatatga ttcctattgc aaaagaaaat caagccacaa ttatcagtat tgttgagatt
     9241 gctgattatg cgaacagcag aggagtagat tcattcggta tgaatatcgg tggaaaacat
     9301 gcgtttccat tcggcgtggt aaaattcgta catgcacagc atagttcaag ctatgaagta
     9361 gacggtatcg ttcagtatat gggcgagcct agcggaatta ttattcaagc agaaggaaaa
     9421 acgatttatc atgcagggga tactgcttat ttcagtgatc taggattgct tgcagaagaa
     9481 ttcgatattg atgtcgcttt cttgccgatt ggcgataact atacgatggg gccagaagat
     9541 gcagcaaagg ctgcgcaaac aattcgtgcc aagaaagtag ttccaatcca ttacaatact
     9601 ttccctgtca ttgaacaaga tcccgaatct tttgtagagt tactggaaga tagtgaagga
     9661 aaaataatga gcgtctcgga aacgctggaa gtgtaggcag aaaatggcga caaaacatga
     9721 tttgatttta gaatatattg aaagtttacc tgttggcaat cgaatttctg taagaagcat
     9781 cgcaaaagaa ttgaatgtca gtgaaggaac agcgtaccgt gcaatcaaag atgcagaaaa
     9841 tgtcggacta gtttcaacaa ttcaacgagt agggaccatc cgtatcgaac gcaaattaaa
     9901 aaaacatatt gaacgtttga catttggcga ggtcgtcagg atcattgaag gggacgtttt
     9961 aggcggggcg gcaggattag acaaggtctt gaataaattc gtcatcggcg cgatgactaa
    10021 acatgccatg gaacgctata ttacgccagg atcactaatg atcgtcggca accgggcgga
    10081 agtccaaaaa ttagcattgg aagatggcgc cgcagtattg atcacaggag gattcaatac
    10141 gactgctgag attgcaaagc tagctgatga tcttgaaatg ccgatcttac gcacctctta
    10201 tgatacattt acagtcgcaa ccatgatcaa ccgagcgtta agcgaccaat tgatcaaaaa
    10261 agatatcatg cttgtcagtg atatctatat gccagctgaa aagactcatt atttgcagca
    10321 gacagatacg atttctgatt atcagcgttt gtcagaagaa acgcagcatt cgcgttttcc
    10381 agtcgtcaac cgccatcatc gtttgatggg gattgttacg gcaaaagatg ttttagggaa
    10441 atcgccaaac cagatcatcg atcgggtgat gacgaaagaa ccaatcagtg taaagaaaac
    10501 aatgagtatt gcctctgtta gccatcaaat gatctgggat gggctagaag tcatgccggt
    10561 cgtttccgat gacttgacat tggaaggctt gattacccgg caagatgtaa tgaaagcgat
    10621 gcagcttgtc cagcgacaac cgcagattgc agatacgatt tcggatcaga tatctggaaa
    10681 tatccatacg attgatactg accgtgaagg aaatcgtttg gaaaacccta agttcaaatt
    10741 cgtagtagca ccacaaatgg tcaatggcgt tggaaccatt tcttttggcg tacttagcga
    10801 aatcatttct gatgtcgcac aaaaaacaat ggtgatgaac caaaaacgaa atatcttgat
    10861 tgaacaagtg aacctacatt atttgcggct gatccaattg gaaagcgaat tagacattcg
    10921 tccacgtgta ttggaaatcg gcagacgttc cgctaaactg gatatcgaag tgtttattga
    10981 aaacaccatc gtttccaaag caatcgttgt ttgtcaagta atggaacgtt cttagaaagc
    11041 aggagtgaaa tgacagtaca gcaagaaata gtagatacaa taaaaaaata cgataaaatc
    11101 attatccaca ggcatttgcg ccctgatcct gatgcattag gatcacaagt aggattagcc
    11161 gaactattac gggaaagttt cccagaaaaa gaaatacgtc aagtaggtga aacgattgaa
    11221 gggcttcgct ttttagcaga aatgcaagaa gttgaagatg tcttctacca aggagcgcta
    11281 gtcatcgtga ctgatacagc taattcaccc agaatcagtg atcaaagata tcagttggca
    11341 gaaaaactga tcaaaatcga ccatcatccc aatgatgacc cttatggaga tcttgtgtgg
    11401 gtaaatacaa aagcaagtag ctgtagtgag atgattgcag aatttgcttt gatgtttcct
    11461 gaatctttaa agatgaacgt taaggctgca cggttacttt atgcaggaat cgtcggagat
    11521 acagggcgct ttttgtatcc ctccacgacg tcccgtacat tagagattgc ttcgatattg
    11581 agaaattatc catttgatgc aagtgctttg aacagagaga ttgaacaaat gccgatgaaa
    11641 gtcgctaaac tttccggtta tctttatcaa aatatccagg tggatgaaaa tggtgcagga
    11701 agaataatcc ttccgcaaga aattcttgat aaatatggaa tcgatgattc agagacagct
    11761 tcgatcgttt cacttcctgg agtgattgac gaagtgctgg cttgggggat ttttgttcag
    11821 cagccttcag ggtattaccg cgtacgttta cgttctaagg ggccgatcat caatgaattg
    11881 gctaaacgcc atcatggagg aggccatcca ttagcaagtg gtgcgaatgc aaaagattta
    11941 gcagaagtag aggaaatcta taaagagatc caagatatat gccaatcgta taagagcaga
    12001 aaaacagaat gatacttcgt tcgaaaacgt gccttttgta gtaaaaatca caaatgtatc
    12061 ttttcaagat cttctttttc cgttacaata gtgctcacta aagattttaa aggagaaaga
    12121 agatgacatt accaaattgc ccagaatgtg gctcagagta cacatatgaa gatcgaggct
    12181 tgttgatttg cccagaatgc gggaacgaat ggaacaaaga agaacaagaa actgtcatag
    12241 aagacggatt agtggtatta gatgcaaatg gaaaccgtct gttagagggc gatagcgtga
    12301 cagtgattaa agacttgaaa gtaaaaggtg cgtcaggtgc cattaaacaa ggaacaaaag
    12361 tcaagaacat ccgtttagta gaaggcgatc ataatatcga ttgcaaggta gaaggatttg
    12421 gaccgatgaa actgaaatcg gaatttgtga aaaagaatta aagaatattc aaggtctttt
    12481 cacattcttt tcctactact aatgataaaa taaagtaaac gaaaaggagt gaaacgaaaa
    12541 tgtatggtta tggaatgtat ggttttttag atccgacatt tcttttggtc attcttggat
    12601 tagttatttc cggaattgcg tcagcgtacg tcaatagtac tttccgaaaa tacgatcaag
    12661 tgagaagcaa aaacaatgtg actggtacac aagcagcaca atatatatta caaagtcaac
    12721 agataaataa tgtcggtgtt caacaaattg ccggagatct cacagataac tacaattcag
    12781 gtaataagat gttgagtttg tctcaagcaa ctgcacagtc tacttcagtt gctgcgatag
    12841 gtgtagcagc tcatgaatgc ggacatgcgg tacaagatgc ttcgggttat gtcccattga
    12901 agattcgtgc agcacttgtt ccagcagcta actttggttc gatgatttcg ttccccttga
    12961 ttatggtagg tgtattgctt agctggaact ctacgttaat caatatcggg attttcgctt
    13021 tttctttagc attacttttc caattggtga cattaccagt cgaatttaac gcgtctcggc
    13081 gagcaatcca aattttgagt gaaggcggac tactgacgga agaagaagta ccgatggcaa
    13141 gacacgtatt atttgcagca gcactgactt atgttgcagc agcgctttcg acattcctgc
    13201 agctgttgcg cttgatctta ttgttcggcg gcaaccgaag agattaaaat aaagaagttg
    13261 tgaaatcagc gctttgatct gagctaatac cgagagttag ctgattgaat accatttatt
    13321 tggaataa
//
LOCUS       DAZKCW010000064        13212 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000064 DAZKCW010000000
VERSION     DAZKCW010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.066"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            147..1016
                     /locus_tag="ACG84Z_002214"
     CDS             147..1016
                     /locus_tag="ACG84Z_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9163021.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="ACG84Z_002215"
     CDS             1225..2250
                     /locus_tag="ACG84Z_002215"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFP9163022.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="ACG84Z_002216"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="ACG84Z_002216"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFP9163023.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            3333..5036
                     /locus_tag="ACG84Z_002217"
     CDS             3333..5036
                     /locus_tag="ACG84Z_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9163024.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="ACG84Z_002218"
     CDS             5038..7071
                     /locus_tag="ACG84Z_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFP9163025.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="ACG84Z_002219"
     CDS             7082..7522
                     /locus_tag="ACG84Z_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9163026.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="ACG84Z_002220"
     CDS             complement(7722..8849)
                     /locus_tag="ACG84Z_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9163027.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="ACG84Z_002221"
     CDS             complement(8852..9529)
                     /locus_tag="ACG84Z_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFP9163028.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="ACG84Z_002222"
     CDS             9793..11559
                     /locus_tag="ACG84Z_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFP9163029.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="ACG84Z_002223"
     CDS             11574..12011
                     /locus_tag="ACG84Z_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9163030.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="ACG84Z_002224"
     CDS             12024..13175
                     /locus_tag="ACG84Z_002224"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFP9163031.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
BASE COUNT         4488 a         2293 c         2731 g         3700 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gactgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt atggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccacgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaaagtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg actaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcgaaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggaag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatccg gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaaggg
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttggct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt tt
//
LOCUS       DAZKCW010000065        12835 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000065 DAZKCW010000000
VERSION     DAZKCW010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12835
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.067"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..83)
                     /locus_tag="ACG84Z_002225"
     CDS             complement(<1..83)
                     /locus_tag="ACG84Z_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase"
                     /protein_id="HFP9163032.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGK"
     gene            82..930
                     /locus_tag="ACG84Z_002226"
     CDS             82..930
                     /locus_tag="ACG84Z_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFP9163033.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1576..1782
                     /locus_tag="ACG84Z_002227"
     CDS             1576..1782
                     /locus_tag="ACG84Z_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFP9163034.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(1984..2985)
                     /locus_tag="ACG84Z_002228"
     CDS             complement(1984..2985)
                     /locus_tag="ACG84Z_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9163035.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(2990..4903)
                     /locus_tag="ACG84Z_002229"
     CDS             complement(2990..4903)
                     /locus_tag="ACG84Z_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFP9163036.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(5071..5577)
                     /locus_tag="ACG84Z_002230"
     CDS             complement(5071..5577)
                     /locus_tag="ACG84Z_002230"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFP9163037.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            5737..6177
                     /locus_tag="ACG84Z_002231"
     CDS             5737..6177
                     /locus_tag="ACG84Z_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFP9163038.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(6203..7360)
                     /locus_tag="ACG84Z_002232"
     CDS             complement(6203..7360)
                     /locus_tag="ACG84Z_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163039.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(7363..7719)
                     /locus_tag="ACG84Z_002233"
     CDS             complement(7363..7719)
                     /locus_tag="ACG84Z_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163040.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(8017..8910)
                     /gene="sgrA"
                     /locus_tag="ACG84Z_002234"
     CDS             complement(8017..8910)
                     /gene="sgrA"
                     /locus_tag="ACG84Z_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFP9163041.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTGKVNNELDLVPII
                     PTKEQKRNAGSNLKSVLKQPDFVSRGIDHQEKAKETDNRKSDLPETGSRTLNKLITWM
                     GVLLILIVGASYFRSLFHRVK"
     gene            complement(9106..9945)
                     /locus_tag="ACG84Z_002235"
     CDS             complement(9106..9945)
                     /locus_tag="ACG84Z_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFP9163042.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNRTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            10130..11021
                     /locus_tag="ACG84Z_002236"
                     /pseudo
     CDS             10130..11021
                     /locus_tag="ACG84Z_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
     gene            complement(11615..12310)
                     /locus_tag="ACG84Z_002237"
     CDS             complement(11615..12310)
                     /locus_tag="ACG84Z_002237"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFP9163043.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(12294..12692)
                     /locus_tag="ACG84Z_002238"
     CDS             complement(12294..12692)
                     /locus_tag="ACG84Z_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFP9163044.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3890 a         2499 c         1942 g         4504 t
ORIGIN      
        1 ttttttccta ctctccttgt atctttaaca ttaatgagaa cggaaaaaat gataatctta
       61 ttatgaaaat gaggaattct catgagcgtc tccataagac tacaaatcaa aacaatgtac
      121 aacgacttca gcccaaaaga acaggctatc gccgattata ttttagaaaa tccaagcaaa
      181 gtaagtcata gtcctattag caatttagca agtgaactgg gcattgctga ctctactttt
      241 tttcaattta caaaaaaact tggttataat ggatttaaag attttaaaat ggccatgttg
      301 atccaagaaa atgatctatc tgctatttct atccacgaaa atattcagaa aacagatact
      361 gagctcacta tggcgcaaaa ggtgttcgag tctagtattt caactttaaa tgacacaaaa
      421 aagttgttac aacaaaagga tctaaaaaaa gcggctacta ttatcaatga atctaaacgt
      481 gtctattttt tcggtgttgg cggttcagag attgtagcaa ctgacgctta tcataaattt
      541 ttgcgttccc ctatcgcaac ttctcacagc acggattacc atattcaatt gatggaagct
      601 tctttattga cggaaaaaga ctgtgctgtt ttgatttctc acacagggca atcaaaagaa
      661 acaatccata ttgctgaaac cgtaagaaaa actggagcaa aaacaatcgt tattactagc
      721 caagctaatt cttcccttgc taaacttggc gatgtcgttt ttatttctat ttctgaagaa
      781 acagaattcc gatctgaagc tttagcttcc cgtatttctc aactaagcat tttggactct
      841 ctatatgtga ttttgatgtt ttacaacgaa aaagaatcac gtcgttctat cgctaaagtt
      901 cgacatacta tttctgaaat caaagaatag caccataaca gaaaaagcga aaaatccata
      961 aaacaaaaaa agccactacc aaatatttgg tagtggcttt tttggttctg caagggtggt
     1021 acagaacatc aatagtcggt gggttagaac gtatgtcatc gcatctttgg agaaggttgt
     1081 attggtatta ttcgagttac ttgttagatg cgataacaaa gttagtatac agtagtaaaa
     1141 aatttatctt ttcttttttt tattattttt gtttcttatt ttctaaaaaa ttaaaaaaaa
     1201 ttttggtgaa ttaagtattt ccttgataac actggctttt ggcctcattt taggttatca
     1261 tttgtaattt tatttcacag ttgatatgat tgttatgtaa aataaaaaag tttaggatac
     1321 atcgaatttt tggggaaatt cttttggggg tatcctaaat cttttctatt atattcccat
     1381 attttctatt attggtctag acgtatgatg gtaaactttg tacctatctg attgctgaat
     1441 cattaattgc ttatcattag ccatctttgt ttcaagttcg ctagatgatc attttattca
     1501 catcctaaca aacttgtcac atttatagat tcttaatcta tttatcatac aattataaaa
     1561 aaggaggtgc tgcttatgaa agctatccat atttctttgc tttttttcgc tagtgcattg
     1621 attttatttg ctattcatct ttgttcccag ccttatatca ataacaacgg aatattagtg
     1681 gaaccagcat tcttttgctt accactcggc tttttgtccc ttcttgcctc cgcaggcttc
     1741 ggatttgttg ctttttttaa acgatcaaaa caacaaatct gacttataaa atttacgtaa
     1801 aagagatcgt gacaataatc gtgtgatatt cccaaatttc gaataaaagg tgccccttgc
     1861 catctctaac tcctcagtca caagttacaa tattcataaa ccatgaaaag cttgtttatt
     1921 gaaattgctc cttgtgactt ggagctaagt gacagattac aacctctttt gcatcataag
     1981 actttactcc ttgaaaaaca ttactaactt ttgatatgtt tcttgcgctt gtttattgct
     2041 gaaatcaaac tgatattcat ggttcaaaac agcatttttc tccgcataat ctacttttgt
     2101 gactttcacc cccgctttct caaatacaga agttacttct tccatttgtt tcgtaaacgt
     2161 atttgtattt ccatccgtta agaatgtgtt ttgcgtccaa cgatccgcat gtctgaccaa
     2221 ggctaaactt ttgaccttct ctgattgttc aaagtcctta ttatcaaagt aagcccatcc
     2281 acatttttca taaagaaagc tagagatttt atcacttact tgagtaagtg cagaaggatc
     2341 caacagacca gacaaagaaa taaacttcgt aatctgcttg ttctccaaag tcggatcaag
     2401 atgatcagct tttttaattt cttcattttg aagtgctaac aaatattctc cactaatttg
     2461 tgcacctgcc gaatttccac caatcgaaat attcgaccaa tctgcttgat cttttatctc
     2521 ttttttagct gcttgaatgg cttcgttcaa ttggataact ggtgtaggat gttttgcttc
     2581 cggtgatcgt tcataatcta tatttacgat gatttgctgc gtgtctgaac atagatattc
     2641 caaataatca cgacaatcat ttttatcccc tcctacatat gcgcctccat gcatccagaa
     2701 aagaatcggt aattttttct tttccacttt cggtgtgtag atatccatat tattattttt
     2761 gtactttgaa ggataggata tttctttttt tatatcgatt tgttcgattt tttgctggaa
     2821 atcatctggt cgggcatata cttgttcttt ttcacttgtg tcaaattgtt ttctaacaag
     2881 caagctaatc ggctttggtg tgatttgatt aatcaaaaat acagtgacta aaataactac
     2941 gatgataact ggtactgcaa tcactattcg cttgaaccat ttcattcatt taccctctct
     3001 ttcttcgcca aatccatgtg ataatcgtgc taacagataa aaatccacct gaataaatga
     3061 gaagcgaatg tttcttttct ccagttttcg gcaacattct tttttttgca tctgtctttt
     3121 tttgtacttt cactgtcatc tgaatcggtt gcgtatcatc acttgattga tcctctcgag
     3181 gttcattctt tcccttattg tctgcattct ctgtcggatc ttgctttttt ggtggagcta
     3241 ctgggatttt tttgtaatag aaaataatag ttggtatcgt ctcattaaaa atcccttcag
     3301 tcggtccttc aacatttgct aattcgtatc cttcgaatgt cttttgctct gtcatataat
     3361 tttctccata agctccgtaa agctggattt cgtcctggtc tttgagtaga cttttattgt
     3421 tttcatccac atactttacg tttatctgat catggaacac tactttcaaa aagtccgtta
     3481 catgtttcgt gtaggcagca tggtcaactt cctgtgcctt tccatgccct gctccttcta
     3541 ctaataaaag atctttatac cctcctgata actcatataa tttttgcgcg ttagacacag
     3601 gtactacatc atctgctgtt ccatggataa tcaatttagg caatgaatct gacattccaa
     3661 tcgtaggtag agcagctttt gtatccaaat gcatctcctg atcaaaatag tattgtttca
     3721 aaaggcccat aaataaatct tcatgctctt gatccccaat gatgtctaac tgatttttta
     3781 tggcatccgg tagtgcgggg gctactgtct ggctgtacgt aaaacgtagt tgttcatcaa
     3841 ttgatgcaaa tccgcaattt tcaataattc ctttgacatt gacaggaata tctttcgcta
     3901 atacagacat catcgtagct gctcccatcg aaccaccata aagtaaaatc ttttgagatg
     3961 gccgctctcg aacttcttga tttatccagt aaaggacgtc atctgactca tattgtccat
     4021 aggtcacata atcgcctccg ctattaccag tcgctctgga atcaacaaat aataaattat
     4081 acccggcctt ataaaaatca ttgtattctt ctgtaacgat cccgttattc caattccctc
     4141 gaaatccgcc atggatcatg actgttttat ctgaaccttg atcgacataa tatgcatata
     4201 catccatcat tttgccatct tgtttgttta gtacagtttg atgaagttgt tttgtatttg
     4261 gatagaagcc tgtgttttct gtaggcgttg tcccatcatc tgtacctcca agcatcgaca
     4321 tcaacacact gttttttgca aaagcgatat cgtacaatag ataagtagca atcagatgtt
     4381 tgataatctc tttatctaca ccataatcat taacagcaag ctcagtgact aataactcta
     4441 ttaattttga cttgatgtct tctgttggtc cattaagtat ttctgtcatc tgtttaccga
     4501 agtaattcaa atattcttta ccattgaaat tttcaccttt accgatatca tcattttctg
     4561 tcccattctc tttgtcactt actttagcag aagaggattc gtcgtttgac atttttgtag
     4621 ctgttgcttc ttctgtttgt tggttatctg tggtagcggt cgtttcttga tctgtgctag
     4681 taacagatgt ctcaaccgtt gtttcagtat ttgtttctgt ttgtgaagta ctcgatttcg
     4741 tttcatttcc agcatcagta gtttctgtgg tttctacctc ccgagattcc gattcggaag
     4801 aaatgctctc tccatatact gtccattgcg ggacgcttgt acttacagca aataagatga
     4861 ccaacgctcc ctttaatact tgttttgttc tcaagctatt cactcctttt tatgtttcta
     4921 ggagaattat atgtaaacgc aaacattttt tatacaaaaa ataaatggtt tatcccataa
     4981 aaatagaaca ggattatttt ctcattttac gtaataaagc agaatggata aaccagtatc
     5041 cattctgctt tttttaaacg aagaaacaac ttattgctcc aaaaatgtca gaaatcgttt
     5101 atcccaaatt ttctcgtaaa aagcgattgt ttcctttgct ttcataaaag gattatcata
     5161 agttgtcgtt gctcctctac acatcataag ctggtatcct aatccatgag caaacttcac
     5221 agtcgtatct atacaatact ctgcttgtgc cccacataat tcgatcgaat gacagtccaa
     5281 ttcagttaat aaaacactca aattagtctt ataaaatgaa ttcgcatggg tttttctcac
     5341 aaaataactg tgctcaggaa tagataattc cgacaatagc tcccatggtt ttgtttgtgg
     5401 cactaattga gcatcttcgt gttgaacgaa aataactggt ttcccaatcg tttcgtatgt
     5461 tttgattctt ttattcacta atgctgtcac tgtttctaat tcgtgtatcg gcgaagaatc
     5521 aaaacatacc cctttttgta aatcgatcac tactattgcg tcggctgtgt ttgacatact
     5581 tgtgccttct ttcttttttc ttgatttaat agtatttctt atctagctag ttccattata
     5641 cgtgacaaca ttttcttatt ttacacctct aaatggcact tttcgactat ttcttcatgt
     5701 tattatttca taaatactta gctattggag gaatgtatga tgattaaatt gtatacaggt
     5761 tctggctgct cgtcttcaag acgcgcaaaa cgttggctta tcgtccatga tataccgttt
     5821 atcgaacaga acttaattcg tcaaccacta accaaaaatg aatttatcca cttactaaaa
     5881 ttgacaaaca acggcgtgac cgaaatgctc tctactcatt ctattagtta taaaaatctt
     5941 gttcacagaa tagatgaact cagtttgagt gaactatata ttgagattcg tacatcccct
     6001 tctttattga aaaaaccgat tatctacgac caatctgcaa aacttttgac tggatttagc
     6061 gaagataaaa tcaggatgtt cctttctaaa actaaaagaa agcaagagct caacgaactc
     6121 ttgctttctg gtcatcttgt cgattttaaa gaaaataatc tttttgcaat gtcttaattt
     6181 tggcataaac aatctgcttt tcttaattaa cgaaatccaa tttttccaat atggatctat
     6241 ttttctcatt cctgattttt atgatttcag ctttcagacg cgcccaatca ttttttgtag
     6301 gttgtccatt ccagtaaaat atctgtgtat tcgtttgatc atatgccttt ttgtcgatag
     6361 gataatcgct aatgacaata tcaggtaact gatcagcgga tgcactatat tttattgggc
     6421 gttcagtcat agataatatc cttttctttg cccataattc ctgtgtttta ccatactttg
     6481 attgaatata gaatatgaca ggttgttcgt gttttataaa aatatccctg actaacatac
     6541 agtattgaaa aatcaaccgt ctgttctttt cataataagt attaagctct ggaattctgc
     6601 gagctacccc actaaaaaac tgttgcatga ttggatacat cactggaaat atatgctgaa
     6661 aatctctgtc ttctgctgat tttccaaaag catccacctt cttttttgtc ccaaaaaccc
     6721 ttgaatacaa atggatcatt gccaaattga catatagata atttttttct gaagttgtaa
     6781 aacaaatctt gaagtttttt tcaaaatttt ctacaataga cgattcaatc cagccccaac
     6841 tttcttgtac tttatctgga gtatccaaca aatcttcttc caaataggtg ttcattacac
     6901 caaacataaa ataaaggtaa gcttgctctg ttggagtgat gtgattcatc gaccagaagt
     6961 ttgcttcaaa aaaaggctct agtatgtaat gcgtaaactc ttcttttgtt atcaatggat
     7021 gcacaaattt gttcatctct tctgggacat acgtaatcga gtggccttgt ttcattcgtt
     7081 gcaacgaaat tcttagtagg ctgatccatt tctttctatc tatactacgc gtatatggcg
     7141 catgtttcgc aaatttttct aatagttgac gtttattttt tatacttgat aatatatcag
     7201 aatgattttc gtcgaatgac tgccaataca tcaagtgaaa aaagtatcgg atacggtatt
     7261 cttctccttc tatcggatta ccttttttca agctgcaaga taaatgatag tttttcaaaa
     7321 tagtattaag ttctcttaat tttctttgaa tcgtacgcaa acttatataa ttttttgact
     7381 aagattttct aaggattgat aagtaccttt gtaaagtgaa tccagtaaaa tataaccaat
     7441 cgttccctct aaaagtatag aataaacttt actcagtaaa aactgagaag aaaactcgac
     7501 ttttatcatc ttgttttctg aaagaaaaga taatttatat tctggatacc tttcgcaaaa
     7561 cgattctgct tgttgaatca ccgaattcat cttagccagg gtgtagttta gatctaaagc
     7621 gatatccttc accacatata atttctcgtc tctttcataa caatagttca aaaattgata
     7681 tacttgcctt tcattgatat caataaattc ttcaaacaaa gtacatactc ctttttatct
     7741 attatttaga cttattccga cagctacatg aataacgtac aaatagattc gttactgatt
     7801 tttcagagat actaccatgc gcagtgtgca ttgtcaatta ttcttgctct tattttccat
     7861 ttgtgttcct gttatttcct gtttctcaaa tatgttagta aacaaaaata gatctggcaa
     7921 agctacaact tcgccaggca atacagcact ctcgaatgaa atattcactc aaaaatctat
     7981 cgttttattc aattttagat ctgttgcttt tattctttat ttcactcgat ggaagagaga
     8041 acgaaaatag cttgctccta caatcaaaat gagtaacaca cccatccatg taattagctt
     8101 gttcaaggtt ctactaccag tttctggtaa atcgcttttt ctattatctg tttctttcgc
     8161 tttttcttga tgatcaattc cacgagaaac aaaatcaggc tgttttagca cactttttag
     8221 gttgctccct gcatttctct tttgttcctt agttggtatg ataggtacca aatcaagttc
     8281 attatttact tttcctgtgc tgctttcgct gctcgtgctt cctgtgctac tttcactact
     8341 cgtactctcc gtactgcttt cgctgctcgt gttttctgtg ctactttcac tgctcgtact
     8401 ctctgtactg ctttcaccgc tcgtgttttc tgtactgctt tcactacttg tgctatccgt
     8461 actgcttggc ggtccaacaa ctgtccaact gcttggtttc aaattctccg tgatcgtcat
     8521 ctgtccatca taaaaaacaa tcaaatcaac tttatcttta ctcttgatct catcaatcga
     8581 tagttctgca gaaatcatta ttgtatactc aataccagcg gtccattgta cgtcttttaa
     8641 ataaacttcc ccaataactt tttctgaact tccattacca tcccaaccat atgttagaac
     8701 agcatgtaca tcactagcat tcacgctttt gtttggtttg actggaatag taatgacttg
     8761 ttgtgtcatg tcataaacaa tccgatcagt tttcacagta aatgaaagat tctcatttgc
     8821 ccgttcattt gcagaagtac tgattccaat cattgctgca attatactca gcccaagaat
     8881 aacaaataat acggtcgctg ttttcttcat ttctatcact ctccatataa ttaccttcta
     8941 tttgataaag gaattatata aaatgaaaat gatgagaaca cgacagtcag ttgtgaaaat
     9001 ctaacaaaag atgtcgtgta ttcgcttgaa tttgtttact ttttcgttta atcaatgaca
     9061 gacttaaaaa agcaagaccg atatcagcct tgctttcttc atcttttatt gataaacagc
     9121 agtgtatttc ttcatccgct ttgttttata tgcatagagt aacaaaccaa caatcaagac
     9181 taacaagaat aatgtagttg atatagatgc ttcagcccca aagtttcccc cagtaattat
     9241 tgtattttgc gattggatca gagtggagaa aaaaccttgt tcttgcgttc cgctgactgg
     9301 tatacccaaa atagctcctt gtgtccgatt ccaagtaata tgagcaccaa tagccgtaaa
     9361 taaacttcct gtactgtaga taagtgcgct gaaaaagcaa cctgctaaaa agatattgaa
     9421 aactgccaga aatgtcatgt taggattcaa tccgtgcaaa agagcaaata atgcagcaga
     9481 tccaatcatt gctattaacg gaccaaatct aagcatctga tgctgaaaaa agccacggaa
     9541 taaaagctct tctgatgccc ccactgcaat aaataaaata aaactcgtta tcagcggcac
     9601 aatgtttgcg tttcctgaat ctaaccgata cgcccccgtc aaatataatg gactagtaat
     9661 aagcagaaac actccaattc caacaacgag acctcccgct aaataccccc agtcttttcc
     9721 tcgaacagaa acaccataat cttctattct ttttccttcg accttactag caagaaataa
     9781 agctagtaaa aaaacagcta aatgtccgac cgtaccggca attgctccaa tccattcact
     9841 atttccaata aacatatccg caagtgcatt attgacaaga attcctaaaa caaaaccaac
     9901 taagactatt aaaacagatc caatcaaccg aataatcctg atcatctttc atccctcctt
     9961 tatattaagt ttaacaaccc ttttctttct tgtctcgtga aaactatgta aatgttctcc
    10021 atcatagaga gaatagattt ttacgaacta agaatatcta cagcaacctt acgaaaatga
    10081 aagactgtct ccctaattct tctgttagac tgtttttaat aaggaaagga tgggaaattt
    10141 tttgaaaaaa caactactaa ttatgtgcct ttcagcatgt gcaattttac tattctcagg
    10201 ttgtagcaag tccaatgaaa cgattgcaac gtttaaaggt ggaacactta cagttcagga
    10261 tttttatgat aacccaaaag ttaaatcaaa taatcaaaca ctattaaaaa aaatgattgt
    10321 cttcaaagca tttgatgatg tatacggaaa agagatttct tcaaaggaag taacaaaaga
    10381 atataatgaa caaatcaaaa aactcggtcc aaactacaag gaacaattaa aagcagttgg
    10441 ccaaacagaa gagacatata agaaactctt taaacagatg ctggctttcc aatacggttt
    10501 gaaagccaat gtaaaattaa cagataaaga tctagacact gcttggaaag aattctatcc
    10561 agaagttagt acacagatca ttctattttc gactaaagaa ggagcagata aagcaaaaaa
    10621 agaagcaaat gaaggagaaa atttctccaa gcttgttcaa gcttatggaa aaaataaaac
    10681 attaaaggaa actgatggaa aaatgaattt tgattcaacc aatccagaga ttcattccta
    10741 ctgaagtaaa aaaagcagca tttaaactaa aaaacgggga agtttctgat atcattcctg
    10801 taacagatcc aacgacttat cagcaaagct attatctagt aaaaatggta aaaaaacagg
    10861 ataaaggttc taataaagac aaatacaaat ctgagctaga aaaaattgct accgaagcaa
    10921 aaactcttga tacggaattc atggataaaa caatccgtaa agtgatgaaa aaagacaatg
    10981 taactattaa agatccttat gtaaaaaata tattcaaata aacaaatttg acccaattgg
    11041 ggatgtggca aaatttgaga agtgattttt ggaaattcct tcttattttt gaggcaaacc
    11101 acttttgcca caacttcatc ggggcctttt tttatttgta ccaaaacaaa tcactggatt
    11161 tgttacaatc atgaggatat aatttaaaaa agttttttat ttctatcaca tgaatcaatg
    11221 cgctattaag tagattcttt catgcttccc tattttttca cttgccgtat cgcttcaaaa
    11281 acaactatca taaactcaaa ctcgactgaa aagttatttt aaaaaagact aaaaatatcc
    11341 cttctggact tgttcttctt attctgttat actagagaaa cacgaaagat atttttatgc
    11401 gacacttttc atttgttttt atgaaattta ttcaaaactg gcgtaacttc agagttacaa
    11461 ggatgtatta gaggttaggg aatacatcgt ttaaatgaga aataagtaat agttagtaat
    11521 agtcacccaa actttaaatt aatgaatatt gaatcgtcag atagcctcct cgagttttcg
    11581 agaaggctat cgtttatttt atggagaaat tgattcagaa gtaatcagcg acctttttta
    11641 gttcaccaat cgtttctgct tggaaagttt gcacccaatc ttcttggaag cccctcactg
    11701 ctttatcaat cgagggcatc tctaatactt gatctagtag ctctttacct aacgttatcg
    11761 catgagctcc agatcgaatg gctgtagtga cttgttcaca atttttgaaa ctagctgcta
    11821 atatttttgt tggtctttgc gtacgttcga tctcagtccg caacgaatca atcactttca
    11881 tagcatcaat gccttgattt tgcatcctgt tataataagg tgcaatataa tctgctccat
    11941 tattaatagc taaataccct tgtaattctg tgtaaatagc tgtaccggta atcaaataac
    12001 cttctttttt caactttttg atcgcttgaa ggcctgcttg attcaccggc accttgataa
    12061 acgtatcttt tcccagttct tctatgataa ctcgagcatc ctctatcatt tcttcttccg
    12121 ttcttcctat tgtctgaata tggataggaa tctgtccgat tatttttttg atttctttca
    12181 tatgcgagaa gaagtttgac gctccttctt ttttcagaat tgtaggattt gttgttacgc
    12241 ctgttaaatt caaaaactgt tgacaagaat aaatactttt tgtatttgct gtatcaagca
    12301 tgatttccat atagctttcc cccattctga tcctcttgat cgattttaat gattgtcccc
    12361 tttcttaaat gcggcatttc cttatcttct acatacattg ttcctggaag ttccggctca
    12421 tgagatccat caaattttat cgtgatatgt cctaattcat tcaaattagt ttggacaaca
    12481 tctcctactg ctgtgattac atacatttgt ttatcaaaac agagcttcat atcacaagtt
    12541 atttcttttc ttacctgatt caattcaatc ttataacaat aatctgttaa tgtttccggt
    12601 gcttcatctc caaataaaat cattattttt tctttcctga atacttctgc ttctatacca
    12661 acatctgtta caaccgtttc aaagatcgtc atctctgttc ctcctcgtaa aatatcattt
    12721 gtctaatagt ttttattcaa aatgtttcta gattataaaa tttattgaat aacacattcc
    12781 taacggaatt tgtttcgata ttgtgtgatt tctcagagta caatggatgt atgga
//
LOCUS       DAZKCW010000066        12159 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000066 DAZKCW010000000
VERSION     DAZKCW010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.068"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(18..293)
                     /locus_tag="ACG84Z_002239"
     CDS             complement(18..293)
                     /locus_tag="ACG84Z_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163045.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            587..1402
                     /gene="thiD"
                     /locus_tag="ACG84Z_002240"
     CDS             587..1402
                     /gene="thiD"
                     /locus_tag="ACG84Z_002240"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFP9163046.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1607..3058)
                     /gene="cls"
                     /locus_tag="ACG84Z_002241"
     CDS             complement(1607..3058)
                     /gene="cls"
                     /locus_tag="ACG84Z_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFP9163047.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3400..6066
                     /locus_tag="ACG84Z_002242"
     CDS             3400..6066
                     /locus_tag="ACG84Z_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFP9163048.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6430..7182
                     /locus_tag="ACG84Z_002243"
     CDS             6430..7182
                     /locus_tag="ACG84Z_002243"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9163049.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7204..8358)
                     /locus_tag="ACG84Z_002244"
     CDS             complement(7204..8358)
                     /locus_tag="ACG84Z_002244"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFP9163050.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8543..10984
                     /locus_tag="ACG84Z_002245"
     CDS             8543..10984
                     /locus_tag="ACG84Z_002245"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFP9163051.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11314..12018)
                     /locus_tag="ACG84Z_002246"
     CDS             complement(11314..12018)
                     /locus_tag="ACG84Z_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163052.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         3908 a         2147 c         2545 g         3559 t
ORIGIN      
        1 taaagaacag ttagaagtta aaattgctga ttcacataga gtttatgact tcttggaaat
       61 tctttttcaa tcagtttttt catctgttta tgaaattctt ttttttcagt aaacataaag
      121 gtttgggtat cgtaaccttc ttcatgtagg aaatagatta ttcctttttc tgtgttttgc
      181 gtataagctt ttatactcct gtcttttttg aaagaacaga tcgtatagcc atctatttgg
      241 tctggtagtc gtttgatttt cttcaaaatg acttttttat cctcaagttt catttttttc
      301 acctgacttt atttttttca tatggaaatc atagcgcctt tggttatatg aaaacaagaa
      361 ggatactgaa atatatataa atcaaatagt ggttatttat tattagaata gcgaatacaa
      421 acaaatgaca actattttct gatttattac aaatgttttt tcaaataaat ttgattacca
      481 agaaaaggta gtggtatatt tactgaggga tactttgaaa aacatatgat agaaacagta
      541 acagcattat gaaaaatctt tttataaaaa tggaggaatc gatttgatgg aagatcagta
      601 tgtacaagca atgacgatcg caggatcaga tagcgatgga agcgcaggga tgcaagcaga
      661 tatgcataca ttctttacaa gaaatgttta cggtgtttct gtcatgaccg catgtgttgc
      721 aggtaattct tacggaatcg gagcaagtgt gacattgcca acagatttta tcgacaaaga
      781 atttgaactg attgcgaagg actttcaaat acgtgcagct aaaacaggta tgctagcaga
      841 ttcaaagttg attgagacag ttgtaaaaaa ttaccaaaaa tatgattttg gaccattagt
      901 cgtggatccc gtaatcgtaa cgaaacatgg aaatctttta ctagaagaat ctgctttgca
      961 aagcttgaaa gaaaagcttg tccctttggc cgaagtactg acacctaatt tttatgaagc
     1021 agaaaagctg actggacgga cattagcagc tgaagaagat tttgtgcaag cagcaaaaga
     1081 actgcaagat atgggtgcaa aaaacgttat gatcaaagga catcatgcta aagatgcgca
     1141 gcaagaaaca gtcaatgact acgtattgct cgaatcagga aaatcatttt ggttaaatgc
     1201 accattttat cctaccgacc ggatcaacgg aactggcgat tcgctatctg catgtattgc
     1261 agctgagtta gcgaaaggaa aaacagttga acaagcgatc cgattggcaa aagactatgt
     1321 aaaccgtgca attcgtgaag aaataaatgt agggcacaaa tatggaccca tcaatcattg
     1381 ggcagctggt gaattagagt aaaagaaaga ggtcgtgagc ctgccgtcca gctccgagtc
     1441 acaaggaaca agttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg
     1501 aggagttggc aggagaacac cgtttgttcg gaagaaggga ctgtgacaag atttttgtca
     1561 cagtcccttt aatcttagta tatttttctc tacttgaata aaaaaattat aggattggag
     1621 aaaataatcg agaaatttgt tgcttgaata atagccagtt agacatttcc ttgactgttt
     1681 cagttgtcat ggatgaacaa tgtgtctcat cttctttgaa ctgagtagca agttcttcta
     1741 aaaactcagg atcgtaaatg acagcacttg tttcaaaatt caatcggtag ctacgaatat
     1801 cttgatttgc tgaacctacc atgcagattt catcatccat tatcaatgtt tttgcatgga
     1861 ggaagccgtt ctcatagaca aggatttgta cattttcctt gatcagctgc cgagcataat
     1921 attgtgttgc tcgataaata aaaggatgat ccggtttgtt gggaatcatg attttcacat
     1981 ctacaccaga ggcagttgcg atttttaaag cagcaatgac actttcatca ggaacaaggt
     2041 aaggtgtctg tatccaaaca cgttttttag cagaagtaat caatttgata aatgaaagct
     2101 tgatttgttc cctttcgtta ttcggtccgc ttgaaacaag ctggatggat gtatcagcaa
     2161 gcttagattc atctcgatct gcttttttaa agaaataatt caaatgatag ccgacctttt
     2221 tttcttcagg taccgagacg ttccagtctg ttaagaagcg aagctggagc aaagaagaag
     2281 cggcaccgaa aatccgtata tgcgtatcgc gccaatagcc gaattttttt gttgtattta
     2341 catattgatt ggcaatattg aaaccaccgg tataactaat ctttccatcg atcacaacga
     2401 tttttcggtg atcatggtaa ttcaatcgga aacgaagtaa tgccttttgt gaggtaacaa
     2461 atgtatggac atgtccacca tttttgatta gacgattgaa atcttttgct tttgtaccat
     2521 gagagccaaa tgcatcatat aatattcgaa cttccacgcc ttctgcggct ttttcttcta
     2581 aaacatgtaa gacttgctgg ccgatattat ctgtcacaaa tgcgtaatat tcgatatgga
     2641 tcgaatgttt ggcttttttt agatcttgaa gcagtgaatc caatttctct tgtccgtctg
     2701 tgagaagagt gacagaattc attcttgtca gcggcatacg atttaatgaa gagaagaagt
     2761 cgacaaattg ctgtttgtct ttatcgccca tgtcaggatc gtaatgttca atggtatctc
     2821 ctctaaaaga ctgaaagttt tctaattctt tcaagtcact ttgtcggaga tagaattttt
     2881 tcttatccgt taatccacgt ccgaaaaata aatataatac aaagcccacc ccaggaaggg
     2941 caaacaatac taagagccat gcccaaatgg ctgctacatc tcggggtttg atcaaaatag
     3001 ccaccaaagc aataagtgca tttaatagat aaagggcggt tataatacta gataccacaa
     3061 aaatgttcct ccttacatac aataacatta gtatagcatg atagaagaaa gaagcctacc
     3121 aaggtgaata tacttttcac tcctttcatg aaaatgtagg taaatcgggc taaagtagtt
     3181 gctttttgta ggttaataag gtaggatatt agtacagttg aatatctcct taggggagta
     3241 accggcaacg tttgttgcga taatatcaac agtaagttaa ccaaatggtt ttctggtatt
     3301 gtatgaaatg gtgagaccta agacaaatgc gtatttgtct taggtctctt tttttttcag
     3361 acaggactag ggccaagatc aaaaaatggg ggatgaaatt tggaaaacaa ggaacaagca
     3421 caacaagcgg tctataaaga aacgatcgac tcgttgatgc agcaaacgca gagctcaacc
     3481 gatggattga gcaccacgca agcgaaggaa aaattagaaa gagatggctt gaaccagcta
     3541 aaagaaaagc cgaagaagcc aacttggaaa ttgttcttag aaactttcaa agatgcaatg
     3601 gttatcgtat tgctgattgt cgcactgatt cagatggtca tgggtgacta catcgaattc
     3661 ttagttattt ttgcagtatt gatgttgaat tctataatca gtgttgtcca aacaaaaaaa
     3721 gcagaaggtt ctttagaagc gttgaaaaac ctttcagcgc ccgatgctcg agtgattcgt
     3781 gatggtaagg aaaaaacgat tccggcaaac gaacttgtgg taggagatat cgtgttgtta
     3841 gacgcaggcg attatgtacc tgctgatgga cgtttactag atgcgggatc attaaaagta
     3901 gatgaaggta tgctgacagg agagtcgact tctgcagaaa aagaagtaac ggatatcaca
     3961 agtacggtac caatcggaga tcgtacaaat atggtattca gtggaacgat cgtaacttac
     4021 ggacgcggta aattcttagt gacttcaact gggaataata cggagatcgg acaagttgct
     4081 ggccttttgg aatcaacaac tgagcaagtc actccgttac aacgaggtct ggataaattc
     4141 agtaaaaaac taagtctggc tattttggca ttgtctttat tgattttagg tatccaactg
     4201 tttcgtattt atcttggaga aggtacagga gatatgactg cagatatcgt cagcgcagtg
     4261 atgtttgccg tagccgtagc cgtagctgct attccagaag cattacagtc tatcgtaaca
     4321 atcgtgttat ctttgggaac gaataaaatg gcaaaacgtc atgccattat tcggaagctt
     4381 ccagcagttg aaacacttgg ttcgacaagt atcatctgta cagataagac tggtacattg
     4441 acacaaaaca aaatgacagt tgttgactac tttttaggta atggcgatac tggggatttc
     4501 acaaatgacc cttcaaaatg gacagctgac gaacgtcgct tgatcgaaat cagtgtttta
     4561 gcgaatgatg catcgatcag tgaagacggt actaaattgg gcgaccctac ggaagtagcg
     4621 tttatcgact ttagtgaaaa attaaaccag ccttatcagg aaatccgaaa caactaccca
     4681 agacaagcag aacttccttt cgattctgat cgaaaattaa tgtctactgg acacacgatc
     4741 gataacgaaa attacttgtt tgtcaaaggc ggaccagata tcgtcttcca acgcagtaaa
     4801 aaagtattgc taaatggtga agtcgttccg atgacggatg aattgatgaa aaaattccaa
     4861 gagcaaaatg aagctttttc aacacgcgca ttacgtgtac tagcttttgc ttaccgtcca
     4921 cttgataatt ttgatttatc atttgaagat gaagacgatt tgatccttgt tggtttgctt
     4981 gctatgatcg atcctccacg tgctgaagtg actcaggcgg taacagaagc aagaagtgca
     5041 ggaatcaaaa caatcatgat tactggtgac cacaaaacaa cagctgttgc tatcgcaaaa
     5101 caaatcggga tttttgaaga aggaaacctg gctttgaccg ggacggaact agatgaattg
     5161 acagaagatc aactaaacga agttttagaa aaagtcactg tttatgcacg tgtttcacct
     5221 gagaataaaa ttcgtatcgt tcgtgcttgg caaaataaag gtcatatctc agctatgaca
     5281 ggtgatggtg taaatgacgc accagcattg aaacaagcag acatcggaat tgctatggga
     5341 acgggtacag atgtggcaaa agatgcagca gcgatggtat tgacggatga taactttgct
     5401 tctattgtca gcgcagtaga agtaggacgt aatgtgtttg ataatatcaa gaaagctatt
     5461 tcttatctat ttgcaggaaa tttaggtgcg atcattgcga tcatctttgc cttagttgct
     5521 gactggtcca atccatttac agcattacaa ctgttgttca tcaatttagt caatgattca
     5581 ctgccagcaa ttgcattagg tacagaaaaa gctgaacctg ctacgatgaa ccgcccgcca
     5641 agagatccaa attcaggaat ctttacggac aaaacattga tttctgtaac gtatcgtggt
     5701 gtgctgattg ggattgctgt tatctttgct caatggcttg gcatgcagca ttcacctgaa
     5761 ttcggtgtag ccatgtcatt ttcaacattg atttggtgtc ggacattgca aacattccca
     5821 gcacgttcaa acacacaaac agctatccaa gcagggttct tctctaacag aagtgtctta
     5881 ctagctgtag ttgtatgtag cgcgctttac tgcttaacaa tgatcccagg actgaaagaa
     5941 gtcttctcta tcccatcagc atttggattg acagaagtct ttacatgtat gggaatcgca
     6001 cttgtgacaa ttgttttgat ggaaatcact aaattgatca ttgtacgagt acaaggaaat
     6061 aaataaaacg aatcaacgag gttgtgagcc tgccgtttaa ttctgagtca caaggtgcaa
     6121 tttcaacaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga agagttggca
     6181 ggagaacacc gtttaaggaa gaagttgtaa aatcagcatt ttgagctaat actgagggtc
     6241 atctgattgg acactgttta ttcggaaaga gggactttga cacgactttg gtcacagtcc
     6301 ctttttttat ttatgataga cggaaagcca atcattttat tattcatcaa aagagataga
     6361 atagataaaa gaggagaata atttattccg aaaagtgaaa acatataaca aaaaattaga
     6421 ggaaatcaaa tgaatgaaaa agaatgggat gaatttgctg aagaatatta tgaaatccag
     6481 caagaatcgc aagtaactat tgctgaagat gtaaaaaatt atctgaaaac ggagaaagtc
     6541 ctgcctgctg aaacagcagc agacgttgct ggaggatctg gcagatttct ttccttagca
     6601 aaagaaatta atcgctatga tttgatcgat ttttcttcag gaatgctaga aaatgcaaaa
     6661 aaagaagcag aaaaaaatga gttgccaaat gtttccttta tcaaacagtc gttagaagaa
     6721 tttatccaat caaatgagac atatgaaatg gtttttacag cagcaaatcc agcattggta
     6781 catcttattc aattagaaaa attgatgaaa aagtcaagca aatggtgcgt gataatcagg
     6841 gtagtggaat caatcgatga tgttttttat cctatcgaaa agcaactagg aatgatagaa
     6901 gaagatccta atacatcgcc agttgtaatg gatcaatttg aaacatactt aattgatgaa
     6961 ggattcaaag tgaagaaaaa agattttact tattttacac aggaatcaat tactgaagaa
     7021 ttgatgaagc tatactatga cgcgtacgca aaagatcctg ttgtgaccag gtacattcgc
     7081 aaactattca gtgaaaaacg agaaatcctt agtacgacta agctgaccta tagactgctc
     7141 ctttggtccg cagataaaaa aagaaccttt cacgactcgt gaagggttct ttttatgatt
     7201 ttattatatt ttgtagtaac gaatatcatt ttcgatcttt gtaatcgaaa aaggtacatc
     7261 tgaagtatat tctgcacatt ctccgtgttc aggaagcgtc tcactgaaaa tcgtttcata
     7321 ttcgtcaaca gtgatccgtg ttcgagaatc tagcatctct tgatgagatt gtgcgaagag
     7381 atattcttga tagttttctt ccagataacc tgtaaaaaat tcacttactg caccagaacc
     7441 gtagctgaat agaccgatgc gatctcctgg ctgtagtgat ttcgaatttt ccagtagaga
     7501 agttagcccc aggtataatg aaccagtgta aagattaccg attcgtcggc tgtaacggat
     7561 gctttcttca tagcgagcca taagacgttc ctgattttct tcgtctgttt ggtctaatac
     7621 gctttgcaat gccttttttc ccatcttagt atacggaata tggaaagcaa tcgcctgata
     7681 atcttcgagt cctcgacccg acaattcttt atgtcgattc caaacttttt ggaatgattc
     7741 gatatacgta gaattagata aaggaccatc aacaacagga aattcgctat aatctggacg
     7801 ccagaaatca tagatatctt ctgtcagaaa tacgctgtcg tcttcaatcg ataaaatacg
     7861 cgggttttga gtgatcatca tcgcaacagc accgacacct tgcgtcactt caccaccgct
     7921 tgccaagccg taacgagcaa tatcacttgc tatgactagt acttttcgtt ctggatgatt
     7981 tttgacatat tctttcgcca tgtgcaaagc tgcggtgcca ccgtagcaag cctcttttac
     8041 ttcaaaagaa cgagcaaaag attggatttt cagtaaatgg tggataatta ccgcactcgc
     8101 ttttgaatga tcaatcccgg attctgttcc gacgatgacc atgtcgatta gctcacggtc
     8161 tttttctgtt acgattttgc tggcagcatt tgctcctagt gtaatgatgt cttcatttgc
     8221 acgattgact gccatttggt cttgaccaat ccctatatgg tattttgcag gatcatcccc
     8281 acggctttct gccaactctg tcatatctaa atataaatta ggaataaaaa aggaaagacg
     8341 atcaatccct attttcattt caacacctct ttacttatga taaaaaactt actttactaa
     8401 ggtatcataa aaagattaaa agaaatataa aaaagagaat atttaaggat tgttaaaatt
     8461 taatcttaga aaaaaacaac tggaacaaga gctatttgtt tttacagcaa agaatggtat
     8521 atttttgtag gaggtggctt acttgaaaga agtcgttatg atagatgctg caagaacgcc
     8581 gataggaaag tatcgcggaa gtttaagtcc atttactgca gttgaattag gcacacttgt
     8641 gactaaagga ttattagata aaacaaaact gaaaaaagat aaaatcgatc aagtaatatt
     8701 cggaaatgtc ctgcaagctg gtaatggtca aaatgttgcc agacagattg ctttgaacag
     8761 cggtctccct gtagatgtcc cagcaatgac gatcaatgaa gtttgcggat ctggtatgaa
     8821 agcagtgatc ttagcacgcc agctgatcca attaggtgaa gcagaacttg tgatagccgg
     8881 cggaacagag agtatgtctc aagcacctat gctgaaaccg tatcagtcag aaacaaatga
     8941 atatggtgaa ccaatttcca gtatggtcaa cgacggattg actgacgcat tttcaaatgc
     9001 acatatggga ttaaccgcag agaaggttgc aacacaattt tctgtgagca gagaagaaca
     9061 ggatcgctat gccttgtcgt cccagttgaa agcagcacat gctgtcgaag ccggtgtatt
     9121 ttctgaggag atcatcccag tcaagatttc tgatgaagac gtgttatctg aggatgaagc
     9181 agttcgtgga aatagtacat tggaaaaact gggcacgtta cgtacagtat tctcagaaga
     9241 aggaactgta acagcaggaa atgcttcgcc attgaatgac ggtgcctctg tggtgatcct
     9301 tgcatccaaa gaatacgcag aaaataataa tctgccttat ttagcaacca tcaaagaagt
     9361 agcggaggtc ggtattgacc caagtatcat gggaatcgct ccaatcaaag ccattcaaaa
     9421 attgacagat agatcaggaa tgaatttatc aacaatcgat ctttttgaga tcaatgaagc
     9481 atttgcagct tcttctatcg tagttagcca agaactgcag ttagatgaag aaaaggtcaa
     9541 tatatatgga ggagcaatcg cattaggcca tccaattggt gcaagcggtg cacgtatctt
     9601 gactacatta gcttacggat tgcttcgtga acagaagaga tacggtattg cttcattatg
     9661 tattggtgga ggtttaggct tggcagtctt gttagaagcg aatatggagc aaacacataa
     9721 ggatgtgcaa aaaaaaaagt tttatcagct tacgccatct gaacggcgca gtcaattaat
     9781 agaaaaaaat gtattgacac aagaaactgc gttgattttt caggaacaaa cactttctga
     9841 agagctctcc gatcacatga tcgaaaacca agtgagtgaa gtggaaatcc caatgggcat
     9901 cgcgcagaat tttcaaatca atggtaagaa aaaatggatt ccgatggcaa cagaggaacc
     9961 atctgtcatt gcagctgcaa gtaatggtgc aaaaatctgt ggaaatatct gcgcagaaac
    10021 acctcagcgg ctgatgcgag ggcaaatcgt tctatcagga aaatcggagt atcaagcagt
    10081 gatcaatgca gttaatcatc gaaaagaaga gctgattctt tgtgcaaatg aaagttatcc
    10141 ttcaatcgtg aaacgcgggg gcggtgttca agatatctct actcgggaat tcatggggag
    10201 tttccatgca tacttatcta ttgatttttt agtggatgta aaagatgcaa tgggcgctaa
    10261 catgatcaac tcgattcttg agagtgtggc aaacaagtta cgggagtggt tccctgaaga
    10321 agagattcta ttcagtattt taagtaattt tgctacagaa tcattggctt ctgcctgttg
    10381 tgaaatccca ttcgaacgct tagggagaaa caaagaaatc ggtgaacaaa ttgccaaaaa
    10441 aatccaacag gcaggggaat atgcgaagct tgacccttac cgtgcagcaa cgcacaacaa
    10501 agggatcatg aatggtatag aagctgtagt ggcagctaca ggaaatgata cacgtgcggt
    10561 tagcgcttcg attcacgcct acgcggcaag aaatggatta taccaaggat taacagactg
    10621 gcagatcaaa ggggataaac tagttggaaa actaacggtg cctttggctg ttgccacagt
    10681 aggcggagct tccaatatcc tgccaaaagc aaaagcatct ttagctatgt tagatattga
    10741 ttcagccaag gaactagcac aagtaattgc tgcagtaggg ttagctcaaa acctggctgc
    10801 tttgcgtgca ttagttacag aaggaatcca aaaaggccac atgggacttc aagctcgttc
    10861 attagcgatc tcaattgggg ctattggtga ggaaatcgag caagttgcga aaaaattacg
    10921 tgaagcagaa aagatgaacc agcagacagc tatacaaata ttggaaaaaa tccgggaaaa
    10981 ataaaaaagc aatatcttta gaagaataaa gcaagattta cagttatttt atttactgca
    11041 aatcttgctt ttttctctat cagaaaatat gtttattatt agaatttttt atagttaagg
    11101 ttaggcatct taagaaatca ggcaactcca agatatcttc aggtagaaga gaagtcgcct
    11161 aacattgtag gatcataggt gatttgttgg acaggtcaag ctgatatttg agcctgatgt
    11221 tagaaggaat ttctttttac ttgctgtaga aattattata tgactaaaaa ggctgggatt
    11281 ttaaatccca gccttttatg acaaatagaa tttttatcga tcagtaatcg ctgtcgctgc
    11341 aaattgttcg atcaaaggaa tcaaagtcaa tttgactttg tatttccgtt cgagtgcttt
    11401 ttcgataacg aactcatttt cagtagtcat agaaatagtt gctaatttac gaggttcatc
    11461 agcatttttt tcattaataa ctacttcatg ttcattttgt tctgtgtaaa atttaggata
    11521 ctcagcaacg gcttttgaaa aatcagcaaa acttaaagcg gcattcgtat cagttgagcg
    11581 tgtattttca gttgtgtccg cttttggttt ttccgttttt tcttctggca cactgactgt
    11641 ttcttctgta actggtgtcg caacagcttg cgcagttggt tcatcgtttt tcaatcgttg
    11701 atcattccag taagacacga tttcaataag aagattgtca cggaatcgtt cgaaaatccc
    11761 gttttctcct gaacgaattc tctttaatac agtattgaag ttgtcatcga ttggcacgtt
    11821 gatccgtgta tcttcatttg ttttcccagc taatccgatc gttaagattt gacggttttt
    11881 gggatcaagc atgacttgta acggcaaacc atagcgtcgc aagctctctt cttctagaga
    11941 acggaataat tgtcctctta caccatccaa tgaaggacgg aattgattta ataatttttg
    12001 tttctgtttt ttcttcatat gttctctcct tcgctcatac cctttcgatt ataagaaaaa
    12061 aacagccaaa tgaaaaggag taatgcaaaa aaacttgcgt atacgcaaat tacaacagaa
    12121 aaatttgcgt attttcccgt tttttgaaag aaaaataaa
//
LOCUS       DAZKCW010000067        12136 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000067 DAZKCW010000000
VERSION     DAZKCW010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.069"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..610
                     /locus_tag="ACG84Z_002247"
     CDS             <1..610
                     /locus_tag="ACG84Z_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9163053.1"
                     /translation="KRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWIQLIL
                     DEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSKITVF
                     PKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAYTIQN
                     ATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            723..1001
                     /locus_tag="ACG84Z_002248"
     CDS             723..1001
                     /locus_tag="ACG84Z_002248"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9163054.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            1119..1355
                     /gene="secG"
                     /locus_tag="ACG84Z_002249"
     CDS             1119..1355
                     /gene="secG"
                     /locus_tag="ACG84Z_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFP9163055.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            1458..2213
                     /locus_tag="ACG84Z_002250"
     CDS             1458..2213
                     /locus_tag="ACG84Z_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFP9163056.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            2216..4573
                     /gene="rnr"
                     /locus_tag="ACG84Z_002251"
     CDS             2216..4573
                     /gene="rnr"
                     /locus_tag="ACG84Z_002251"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFP9163057.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            4595..5059
                     /gene="smpB"
                     /locus_tag="ACG84Z_002252"
     CDS             4595..5059
                     /gene="smpB"
                     /locus_tag="ACG84Z_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFP9163058.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            5361..6080
                     /gene="atpB"
                     /locus_tag="ACG84Z_002253"
     CDS             5361..6080
                     /gene="atpB"
                     /locus_tag="ACG84Z_002253"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFP9163059.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            6133..6348
                     /gene="atpE"
                     /locus_tag="ACG84Z_002254"
     CDS             6133..6348
                     /gene="atpE"
                     /locus_tag="ACG84Z_002254"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFP9163060.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            6439..6963
                     /gene="atpF"
                     /locus_tag="ACG84Z_002255"
     CDS             6439..6963
                     /gene="atpF"
                     /locus_tag="ACG84Z_002255"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFP9163061.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            6950..7492
                     /locus_tag="ACG84Z_002256"
     CDS             6950..7492
                     /locus_tag="ACG84Z_002256"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFP9163062.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            7515..9071
                     /gene="atpA"
                     /locus_tag="ACG84Z_002257"
     CDS             7515..9071
                     /gene="atpA"
                     /locus_tag="ACG84Z_002257"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFP9163063.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            9085..9987
                     /locus_tag="ACG84Z_002258"
     CDS             9085..9987
                     /locus_tag="ACG84Z_002258"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFP9163064.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            10010..11416
                     /gene="atpD"
                     /locus_tag="ACG84Z_002259"
     CDS             10010..11416
                     /gene="atpD"
                     /locus_tag="ACG84Z_002259"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFP9163065.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            11430..11852
                     /locus_tag="ACG84Z_002260"
     CDS             11430..11852
                     /locus_tag="ACG84Z_002260"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFP9163066.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4035 a         2155 c         2677 g         3269 t
ORIGIN      
        1 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
       61 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
      121 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
      181 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
      241 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
      301 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
      361 ttactcctta aagcaagcat cagctacgag acagcttggc agcaaccatc tgcctttatt
      421 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
      481 tgctacggca ggggataaag cactgctgct tgttccagaa gcagaacact tggaagcatc
      541 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
      601 gatggattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
      661 tctggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
      721 atatggaaat caaagaagaa aaaaatcgtc ttgctttatt caatgatgag caacaagaga
      781 ttggagaaat gacatggtca gatgcgggcc cagacatcat gatcattgac catacatttg
      841 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
      901 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
      961 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     1021 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     1081 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     1141 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     1201 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     1261 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     1321 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     1381 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     1441 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     1501 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     1561 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     1621 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     1681 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     1741 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     1801 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     1861 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     1921 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     1981 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     2041 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     2101 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     2161 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     2221 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     2281 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     2341 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     2401 agtgaaactt cctttaaaac caatcttgat cgaaggaaca tttcgagcaa atgaacgagg
     2461 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     2521 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     2581 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     2641 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     2701 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     2761 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     2821 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     2881 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     2941 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     3001 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     3061 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     3121 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     3181 tgtatatttg actgatcgag tgattccgat gatcccgcaa cgtttatcga atggtatctg
     3241 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     3301 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     3361 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     3421 tcagctcgta cctatgttcc aagaaatggg tgaattgcat cgaatccttg aaacgatgcg
     3481 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     3541 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     3601 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     3661 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     3721 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     3781 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     3841 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     3901 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     3961 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     4021 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     4081 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     4141 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     4201 aggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     4261 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacaaaaag tgcgcgtaaa
     4321 agtagtcaaa gctgatccag atgaacgagc agtggatttt gaactcgttt ccgcagaaga
     4381 ggtcactgcg ttggaacgtc caaaagcacg caatggaaaa tctggaaaac gagaaggaaa
     4441 acaagcaggc aaacgctcag aaaaaaatgg caagaagaac aaacgatata gtgatagtaa
     4501 gcaaacgttc ggtaagaaaa aagggaaaaa gccattttac aaagatgtca aaaagaagaa
     4561 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaactaat
     4621 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     4681 ggtcttgcaa ggaacggaga tcaagtcgat acgaaacagc cggatcaatc tgaaagatgg
     4741 atttattcgc gtccgcaacg gggaagcttt cttgcataat gttcatatca gtccttatga
     4801 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaagaa
     4861 acaaatcgtt cgtcttgaaa acgaattgaa aaacactgga atcactgttg ttcctttaaa
     4921 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcaaaag ggaaaaaatc
     4981 gtatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     5041 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     5101 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcac aggttttttc
     5161 ttagatcagg agcaccgtgc atggggaaaa attcgcttcg tttttgactg aaataaaaaa
     5221 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     5281 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     5341 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gtttcacatt ggaccaattt
     5401 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     5461 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     5521 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     5581 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacataggtt
     5641 tagtaacaaa aatcgtctta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     5701 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     5761 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     5821 ttccgatgaa actgattgaa gaatttacaa atttattaac acttgcttta cgtctttatg
     5881 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     5941 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     6001 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     6061 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     6121 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     6181 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     6241 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     6301 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     6361 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     6421 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     6481 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     6541 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     6601 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     6661 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     6721 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     6781 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     6841 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     6901 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     6961 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     7021 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     7081 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     7141 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     7201 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     7261 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     7321 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     7381 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     7441 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     7501 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     7561 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     7621 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     7681 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     7741 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
     7801 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
     7861 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
     7921 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
     7981 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
     8041 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
     8101 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
     8161 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
     8221 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
     8281 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
     8341 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
     8401 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
     8461 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
     8521 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
     8581 cggttgatgc cggactatct gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga
     8641 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
     8701 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
     8761 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
     8821 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
     8881 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
     8941 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
     9001 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
     9061 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
     9121 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
     9181 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
     9241 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
     9301 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
     9361 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
     9421 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
     9481 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
     9541 tctgatcagc caagctttga tgaagtccgc aaaatcgtaa atatggcaac aactatgttc
     9601 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact
     9661 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
     9721 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
     9781 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
     9841 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
     9901 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
     9961 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    10021 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    10081 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    10141 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    10201 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    10261 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    10321 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    10381 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    10441 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    10501 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    10561 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    10621 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    10681 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    10741 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    10801 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    10861 attacaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    10921 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    10981 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    11041 ggcttcttct tcaagtgctt tagcacctga aatcgtgggg gaagaacatt ataaagtagc
    11101 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    11161 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    11221 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    11281 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    11341 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    11401 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    11461 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    11521 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    11581 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    11641 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    11701 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    11761 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    11821 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    11881 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    11941 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    12001 tggaacaccg tatatcagag gttgtaaaat cagcgttttg tcctgagtat tagagaaaca
    12061 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    12121 tgaacaccgt ttattt
//
LOCUS       DAZKCW010000068        11445 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000068 DAZKCW010000000
VERSION     DAZKCW010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.070"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            185..1183
                     /locus_tag="ACG84Z_002261"
     CDS             185..1183
                     /locus_tag="ACG84Z_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFP9163067.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="ACG84Z_002262"
     CDS             1295..1804
                     /locus_tag="ACG84Z_002262"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFP9163068.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="ACG84Z_002263"
     CDS             complement(1834..2493)
                     /locus_tag="ACG84Z_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFP9163069.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="ACG84Z_002264"
     CDS             complement(2495..3259)
                     /locus_tag="ACG84Z_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFP9163070.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="ACG84Z_002265"
     CDS             complement(3267..3944)
                     /locus_tag="ACG84Z_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFP9163071.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="ACG84Z_002266"
     CDS             complement(3981..5366)
                     /locus_tag="ACG84Z_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFP9163072.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="ACG84Z_002267"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACG84Z_002267"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACG84Z_002268"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACG84Z_002268"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFP9163073.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="ACG84Z_002269"
     CDS             6305..7162
                     /locus_tag="ACG84Z_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163074.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDGTEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="ACG84Z_002270"
     CDS             complement(7243..7578)
                     /locus_tag="ACG84Z_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163075.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="ACG84Z_002271"
     CDS             complement(7645..9015)
                     /locus_tag="ACG84Z_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFP9163076.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="ACG84Z_002272"
     CDS             complement(9093..9629)
                     /locus_tag="ACG84Z_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9163077.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="ACG84Z_002273"
     CDS             9938..11419
                     /locus_tag="ACG84Z_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163078.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3517 a         2300 c         1855 g         3773 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatggtactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttatt
//
LOCUS       DAZKCW010000069        11319 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000069 DAZKCW010000000
VERSION     DAZKCW010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.071"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(298..2307)
                     /gene="metG"
                     /locus_tag="ACG84Z_002274"
     CDS             complement(298..2307)
                     /gene="metG"
                     /locus_tag="ACG84Z_002274"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFP9163079.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            2575..2853
                     /locus_tag="ACG84Z_002275"
     CDS             2575..2853
                     /locus_tag="ACG84Z_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163080.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            2950..3771
                     /locus_tag="ACG84Z_002276"
     CDS             2950..3771
                     /locus_tag="ACG84Z_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFP9163081.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(4056..5066)
                     /locus_tag="ACG84Z_002277"
     CDS             complement(4056..5066)
                     /locus_tag="ACG84Z_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFP9163082.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(5078..6031)
                     /locus_tag="ACG84Z_002278"
     CDS             complement(5078..6031)
                     /locus_tag="ACG84Z_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163083.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            complement(6021..7091)
                     /locus_tag="ACG84Z_002279"
     CDS             complement(6021..7091)
                     /locus_tag="ACG84Z_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163084.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            complement(7097..8140)
                     /locus_tag="ACG84Z_002280"
     CDS             complement(7097..8140)
                     /locus_tag="ACG84Z_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9163085.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            complement(8141..9082)
                     /gene="opp3b"
                     /locus_tag="ACG84Z_002281"
     CDS             complement(8141..9082)
                     /gene="opp3b"
                     /locus_tag="ACG84Z_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFP9163086.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            9166..9513
                     /locus_tag="ACG84Z_002282"
     CDS             9166..9513
                     /locus_tag="ACG84Z_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFP9163087.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            complement(9583..11244)
                     /locus_tag="ACG84Z_002283"
     CDS             complement(9583..11244)
                     /locus_tag="ACG84Z_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9163088.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
BASE COUNT         3185 a         2302 c         2063 g         3769 t
ORIGIN      
        1 ttcaaacttt atgaatgtaa ggacaataaa aaagagtacc agatgaatca attaaaatct
       61 gcccgaccct ttatcattat gctttttttc tgtttttacg attcctatta gtattattct
      121 aaattaacaa aaatcagcga agctcgtact tctttttcta ggatttattt tggatagttc
      181 tctgtttctg tattatatga ttggcttcaa gtaataagaa ggaatttacg aaaattgctt
      241 ctcaaatttc ggaaaaaggg ggtatgacac aactagtgtc ataccccctt tgaatttcta
      301 tgcgatttct gagccatttg gcatggattt tggtgcttcg attacttgta aagagccatc
      361 tggtgcttct gcagaaagga tcattccttg actgatttgt ccacgcatct ttcgtggttt
      421 cagatttgct acaatgacga cttttttccc gatcaattcg cttggatcag gataaaattc
      481 agcgattcct gacaagattt gacggtcttg gctgtctcca gcatctagtc ggaattgcag
      541 caacttatct gccccttcta ctttttgaca gttgatgact tctgctactt ttagttctac
      601 tttttcaaat acatcaaatt tgatttgttt ttctttcgtt gaaacaagtt ctgtttcttc
      661 tggatcccat ttgactgtat cttcgtttgt ttgagtacct tcagacattt tttcttgaat
      721 aaaagcaact tcttcttcca tatctaaacg tgggaagatt ggtgtacctt ttgcaactac
      781 ttttgttcct gaaggaaatt cgccaaagtg taatccttca agattcattg tttcagagtc
      841 caatcctagt tgattgaaga tcttctctgg cgtttctgtc atgattggct gaagtaatat
      901 cgctgcgata cgcaaagatt cagctaaatg gatcatgaca ctattcaatt cagctttctt
      961 ttcttcgtct tttgctaata cccatggttc tgtttcatca atgtatttgt ttgcacgaga
     1021 aatcagcacc cagatttcag ccaatgctgt attgaattcc attttttcca ttgcatcatg
     1081 gtaacgtccg acaacgttag cagccgtcgt agacagttca ctatcaaatg gagtgacaag
     1141 tgaggcatag tcaggaacga gtccatcaca atatttgttg atcatagcaa tcgttcgatt
     1201 caataagttc cctagatcat ttgccagatc ataattgaca cgggaaacaa aatcttctgg
     1261 cgtaaagaca ccatctgacc caaacggaac agcacgaagc aaataataac ggagtgcatc
     1321 taaaccataa cgttccacaa gcatttcagg ataaacgaca tttccttttg atttagacat
     1381 ttttccgtct ttcatcaata gccagccatg cccaaatact tttttaggta gaggcaaatc
     1441 aagggccatc agcatgattg gccaatagat cgtatgaaag cgaacgattt ctttaccgac
     1501 catctgaaca tctgcaggcc agtatttttc gaatagactt tcatcttcgg agccatatcc
     1561 tagtgcagta atataattgg ataatgcatc gatccataca tacaccacat gtttcggatc
     1621 actcttgact ggtactcccc aagtaaaagt tgttcgtgaa actgcaagat cctctaatcc
     1681 tggtttgata aagttgttga tcatttcgtt tttacgagat tctggctgga tgaattcggg
     1741 atgttcttca tagtattcca atagacggtc tgcgtatttg ctcatgcgga agaagtatga
     1801 ttcttctttt accaattcta cttcgtgtcc acttggcgct ttaccaccga tcacgttacc
     1861 ttcgtcatct ttgtacactt ctgcaagttg tgtttctgta aagaattctt cgtcagaaac
     1921 agagtaccag ccttcatatt cacctaagta aatatctccc tgttctaata aacgatcaaa
     1981 tattttttga acagctgctt tatggtaatc atctgtcgtg cgaatgaatt tatcataact
     2041 gatatcaagc gttttccata atttcttgac atcagccgcc attttatcta catattcttg
     2101 cggttttaca cctagttctt ctgcttttgt ttcgattttt tgaccatgtt catccactcc
     2161 agtgagataa aacacatcaa agcccatcaa ccgtttataa cgagcaattg cgtcacatgc
     2221 aatcgtagta tacgagttgc cgatatgaag tttgccgctt ggataataga ttggcgtagt
     2281 gatataaaaa gtttcctttt ctgccacggg gctcttcctc ctttatcgca tgatgcgaat
     2341 tcgtttcctt gctagtatac cataaaaaaa gcatgctgtt agcttttttt caaaatgaaa
     2401 aagactggat aaacgacttc tatctacgtt caatctatcc tttaaaagga tgaataggtt
     2461 gaataaatgc gggtttttgt tttgtttcat atctactaaa aaacggcttt ttatttctcc
     2521 cctcacacgt ggtataataa agactatcta tcttagtaag ggactggaac aatcatgcag
     2581 aagaaacatc ttttttttac acttagtatt gcttttcttt cattagcaca tttaatattc
     2641 agctattttt atattcgtat gtatggttat tttaacctcc atgggcattt gaacagtttt
     2701 atgacagcag cttggatttt gcgttttatc attgacgtat atatcgttat ttgtggcttc
     2761 tttgccattc gtgaagagcg gtataaagta ttgccgtttt atctgctttt ctttttattc
     2821 aatctcatac ttccatttat ttttcatatt taaatgataa cctagatttt tcaagtaaat
     2881 ccttggtttt ttttcagagt ctgctacaat aaggtaaaaa gtacttttac tgtcaatgga
     2941 ggtggtcaga tgaaccgttt tgcttctaaa gaagaagaaa aattatatta tgaacataaa
     3001 gcaagtgaag aagaatttct taactggtat caaaaacagg aacgtccaga atatgacaag
     3061 ccctctttga ctgtcgatat cgtactgatg tgctataaca aagaagaaga tcagctgaaa
     3121 gttttgttga tccaaagaaa agggcatcct tatcgaaatt catgggcatt gcctggtggc
     3181 tttgtccaaa aggatgagtc aactggagaa agcgtcttaa gagaaacaaa ggaagaaact
     3241 ggtgtggtta tttcaaaaga aaatattgag caactgcata cattcagtac gcctaatcga
     3301 gatccgcgag gctgggtcgt cacagtcagc tacttagcct ttattggaga agaaccgcta
     3361 atcgccggag atgatgccaa ggaagtacgc tggttcacac tagaacgtca tagtaacaag
     3421 atccatttat ctagcggaga agtggctatc tcgcttgatt tagtcactgg agagtcttct
     3481 ggcaaagata ctttggcttt tgaccatagt caaatcatct tgaaagcatt caaccgtgta
     3541 gtcaataaaa tggaacacga gccgcaagtt ctacaagttt taggtaaaga tttcacgatt
     3601 acggaagctc gaaaagtatt tgctaaattc ttagggatcg attataaaac gatcgatcat
     3661 tccaatttta agaaagctat gctccaatat ttcgatgaga tcggtgaacg tcctgtagga
     3721 atcggccgtc cttcaaaaat ctatcagctc aagccggggc accatgaata aggttgtgag
     3781 caaaagattc agacctaatc attcaagaaa aaacgcaaaa acaactcttt gtgagttacg
     3841 ttttttgttt cagaattttg atgtattcgt aaactttctg aataaaaaat taacaatagc
     3901 agaaaaagct cgtacgaact ttttctgcta ttgttttatt ggtttgtcat aattagtgag
     3961 cttttcttca aaagaaaaat tcctagaaac aaaagtcatt aagacttttt attaacaagg
     4021 ctaaccctaa cgctcctatc agtttcattc attttttatc ccttgataac cgaatgtctg
     4081 cccatttttt ctactacttg gctctttctt acggaattgc tttcttctgc tccgtcggta
     4141 ttgatcaaaa gaaatttttt attataccat tgggacttat aacgcaattt tgttattaat
     4201 ttatgccagt cgtgaataga aaaatcagca tgtgcctctt cttttggaaa agattctaca
     4261 aataagtagt catattgttt gaccaatttc ccagataatt gttcaagata atcttctcgc
     4321 tggttctttt gtttcagata aagatccatt acttttctct tttgtttctg ataattgctt
     4381 gcctgatcta acctgatctt tctatggtga gcggagcgga ctttcacatt caatttccgc
     4441 tgtgcatgtt gcagcttttc ttctgtctgg tgaaattttg gtaaagttac ttctagaggt
     4501 cgagatgttt ggatcaatgt cttcggatga taggcgatcc cgatccattt agctaaagat
     4561 tcttttttta ctggcgaaac atcacaaagt agtgcgacat aaaattcttc attatatcga
     4621 gcagaaatcg tagcggagcg aatcgatcct tcaactggcc gatgctgatt tatcttgatt
     4681 agttcttttt gttttggtaa ctttaagtag ccattttcca gatagatcgt acgggtttgg
     4741 ttgttggtcg tataagattg ccacatactt tttttcgttt taagctttgg gaagctggca
     4801 cgtcccttga aataattgcg aaaagcccga tccaaattaa gctgtgcatt tgctaaagca
     4861 agactgtcta cttcttttaa gaatgggtat tcttttttta atgtagcggg tgtgagcgaa
     4921 aaattggcta ctcctgtttg ttgccaactt ttctgccgct ttttcagcaa atggttatag
     4981 gtaaatcgag cacatccaaa agtacgaatc aattgctgtt tttgttcttc tgtcggatac
     5041 atacggaatt taaaagcttt tagcatctat gtccctccta gttagcaacc agaagagatt
     5101 ccttttgtcg ttttagtttt tttgcgtaat atgggacttc ctgctcagtt gcatagacaa
     5161 aatgttctgg tgcgatttca cgaagttgac gtacttgtcc gtcatctggt tcaggttgat
     5221 atttgattct tctgcgtttt ctctcatggt ctggatctgg tagaggaata gcagataaca
     5281 aactttctgt ataaggatga acaccgtgat tatagatttc atcacttgtt cccatctcta
     5341 ataacaagcc gttatgcatt acaccgattc ggtcactaat atgtttaacc atcgacaaat
     5401 catgtgcaat aaatagatag gtcaattgat gttctttttg gagatcttgc aacaaattga
     5461 ccacttgggc ttggatcgac acatctagtg cagaaattgg ttcatcacaa atgataaaac
     5521 gcggttttac tgccaatgct cgtgcaatac caatacgctg gcgttgccca cctgaaaatt
     5581 catgaggata acgagtaccg tggcttggat tcaatccaac agttctcaat agatcatcga
     5641 ctttttttgc acgctcttca gatgatttag ctagtccatt aacatcaatt ccttcggcaa
     5701 tgatatctct gactttcata cgaggattca acgaagcgta tggatcttga aagatcatct
     5761 gaacatcatg ccggaatttc gtcaaacctt ttttatcttt gatcttcgtt atatcttgac
     5821 cgtcgaataa tatctcacca tcagtaggtt cattcaagcg aatgatcgta cggccagtag
     5881 tggattttcc gcttccagat tctccaacta aaccgaatgt ttctccttca taaatgtgaa
     5941 agctgatgtc atttacagca tgtacttcat tcttttttcc tacattgaaa tactgtttca
     6001 atcctttaac ttcaagtagt ttatttggca tcagcaattc ctccttgacc gtaagtatgt
     6061 ttttgtttct ctttaaagat agcccagcga cgttggattt cttctggcgg tgtcactttg
     6121 ggtgcctgcg gagcaagtag ccaagttgct gccttgtgtg tttttgatag ttcaaaaaat
     6181 ggtggttctt gttctgcatc gattttcatc gcgaattcat ttcttggata gaatgcgtct
     6241 ccttttggcg ggttcaataa atccggtgga gaaccaggaa tagcatacaa tcgatcgttc
     6301 gcactatcta atgtcggcat tgaaccaagc agtccccaag tatagggatg ttgcgggttg
     6361 tagaaaattt cttccgatgt tccaacttca acgattcttc ctccatacat gacagcgaca
     6421 cgatcagcga cattcgctac tacaccaagg tcatgagtga taaagataat tgatgtatcg
     6481 atttttgtct gaatttcttt cagcagctcc aaaatctgtg cttgaatagt cacatcaagc
     6541 gctgttgtag gttcatcagc aatcaggatt tccggataac ataccagtgc aatcgcgatc
     6601 acgatccgtt gacgctgacc tcctgagaac tgatgcggat aactgttgat acgtttctca
     6661 gcttcgggta ttccaactaa tttaagcaat tctaatgcag ctttttgtcc ctcttttttt
     6721 gaaactttat tatgctttct aagggactca gcgacttgct tcccaatggg catcgtcgga
     6781 tctaaagagg tcattggatc ttggaaaatc atcgctattt ctttaccacg gattttttgc
     6841 atctctcttt ctgattttcc aacgatatcg ttacctttaa agaggatttg accagcatct
     6901 atattggcgt tgcttgacag caagcgcatg atgcttctgg tcgtcactga ttttccactt
     6961 ccagattccc caacgatcgc caatgtttct cctttattca aatgaaaatt gacaccgcga
     7021 atcgctcgta cctttccagc atacgtatca aaagagattt ctaagtcttt cacttctaaa
     7081 attttcgtca tcgtcttcac tctttcattt taggatcaaa ggcatcacgc aatccatcag
     7141 caagtaagtt aaagccaatc atgataaccg ataaagttac tgccggaatc cataatagat
     7201 aaggcagata caggaatgtc ttgtaccctt cgctcaacat cgttcctaat gaagctgacg
     7261 gaggcgtaag acctaaaccg ataaagctta aaaaggcttc gaagaaaata gcagatggaa
     7321 tactaaacat catttgaata ataatgacac tagagatatt cggcaaaata tgtttgaatg
     7381 caattttcat tcttgattca cctaatgtca atccagctaa aacatattct tgatctttta
     7441 atttcattgt ttgtgcacga acgatacgtg ccattggtat ccagtttgtg atggccatag
     7501 cagccacgat tgaaaaaatt cctggttcaa aaacgaccaa catcaaaatc atgacaacga
     7561 ggtttggaat tcctgataag atttccaaaa aacgttgcat cacgttatcg acacgtccgc
     7621 ctaacaaacc agaaaccaac ccgtaagcta caccaatcgt tacatctagt aatgcagcaa
     7681 taaatgcgat cagcaacgag attctcattc ccataaataa gcggcttaat acatcacgtc
     7741 ccaaaccgtc tgttcctaaa aagaaattta cgtttgaagg gacgtttgct tgagcatatt
     7801 tatcaacaag ttcaccacca accattgctt ttccattcaa tccatcgata ttgattcccg
     7861 gaatacgagg aggcaaattg atataagcca cgttttgggc agttggatca tgaggagaaa
     7921 caaagattgt gatcacagag atcaaaatga tgaccaatag taaaaccatt gaaataacgg
     7981 cagctttgtt tttctttaaa cggcgccatg aatcttggat aaaattcaaa gaaggtgcag
     8041 taatctgttc acgttcttct tcggtatttt tttgtaatgg aagaaattca tccgcaggga
     8101 tatctgcaac tgtttcataa cgctttggta tcatttccat ttatcctcgg ctcccttctg
     8161 aaacacgaat tcttggatca actagaccgt acaatagatc cacgatcaaa ataacaaaaa
     8221 tcagcataaa tgagtaaagg atcgttacag ccatgatcgt aggataatca tttgttgtga
     8281 ttgacttaac gaattgttcc ccgataccag gaatagcaaa gatattttct accaccagtg
     8341 atccggtcat caatgctaca gctaacggtc ctaataaagt catcaatgga atcaaactat
     8401 ttcgaagacc atgtttaaag gcgatttccc aacggctcaa tccttttgct tttgctaatt
     8461 ccacataatc actatgcagt acttccacca tttccgtacg gataaaccga gcagagtcag
     8521 caagcggcga catggccaac gcaattgttg gtaagattgt gtacacaaag ccatcccatt
     8581 ttgcgattgg caaaacttgt aatttgattg caaagatata ttgtaataaa acagcaaata
     8641 caaagtttgg aatggaacga cctaatatcg ctacgagtgt agaagatgta tctgcccatg
     8701 tattttgctt catggcagag atcgttccta aaatcgtccc taggactgtt ccaaagataa
     8761 ttgcctgtaa ccctaactgc aaggatggtc cgattcttcc agctaacaaa tgtgcgactg
     8821 gctggttttt aaattggaag gaaattccaa aatctccttg aagcaaatta gaaagataaa
     8881 tcccatattg tacgataact ggtttatcca aaccgacttg tttatttagc atctcgattg
     8941 tttcaggact caaacgttcc tgattcgtat atggcgtgcc cggcagcaat tgcatcaaga
     9001 aaaaggtgat tgttgcaatt aaccaaagcg tgatgatcat gaaaaagaca cgttttaata
     9061 catatttgat ataactattc actaatgttt ccccctagct tttgacttct gacagatgtt
     9121 tcgctacatt attagataat gaaccaaaaa taaaggagca atcaaatgaa aaaaaaatct
     9181 atcccctacg cagtagcttt tctactgatt ctggttattt taataaaaaa tctcatcaac
     9241 cattccttta cactcattca attatctaat gatctattct tatggtcatt gccgtttctg
     9301 attatcggcg gttttttatg ggtcttttct tcgggtttct tcgatcattt tcagcgatcg
     9361 gtccatcttg cacgaacaag gaaccgaaag aaaaaaccag aattttcctc gctctcgtct
     9421 gccagctacg gtatgtacag cttttggctg atcattgccg gaatactaat tgctctttct
     9481 gctattttca tgcttttttc tttgttagga taagtgaata tgagaacgag gttgcgacat
     9541 ttgccgcagc ctcgtttttt ctcatgctca cggtattaac gattattctt caacgtatgt
     9601 ccatttgtaa tcccatgaag cgcctgccgc atggtgaacg atacctttga ttttttcatt
     9661 cactaggtga ccttctgctt tttggtacac cggaacgaca cccatatcat cagagatgat
     9721 cttgattgct ttttggaaat catcccaacg ggcttgttca tcgccagcgt ctgttgatga
     9781 agctgcttta actgcttcgt catattctgc attgctccag cgaccacggt tgtatgaatt
     9841 acctgtgaca aacaaatcag taaagctgct tgggtctgca tagtcagcag cccatccgcc
     9901 tagtactgcg tcaaaatcac ccgaagttga gcggtcaaga cgtacagaga atggaacagg
     9961 tgttggtttg actgttacgc catccaagtt ttcttggatt gagttttgaa catattcgat
    10021 tacttttttc gatgaatcat catcagaagc catcaaatca aattctaaag aatcaacgcc
    10081 caattctttt ttcgcttttt cccaatattc ttttgcttta tctttgtcat aagaaactaa
    10141 ttttccagct tcttttgcaa agtcttcgtt cgttgttgga ctttttacca tatctgatgg
    10201 gatcaatcct gtagagacaa ctgatccgtc acctagtact tgttttacta aagcttcacg
    10261 atcgatagaa taagaaatag cttttcttag gttcacattg ttgaatggtg aattcttttc
    10321 acgttgattg aattcgatat agcttgtccg cgcttcttta acagaagtat aagctggatc
    10381 gtttgcgttt tgctgtgcta actcaccaga caagatcacg tcatctgctt ggccatcttt
    10441 gaataagttc aatgcagtag aagattcttt tactacactg actttgattt cagaaagttt
    10501 tactgtatct ttgtcccagt aatgatcatt tttcttataa gtccattctg tatctgttcc
    10561 tggtccatca aaatcttcta atgtgaatgg tccattataa acagctttat cacttgcaga
    10621 tgcataggca tccccatttt cttccactac ggattgtttt tgtgggaaaa atgatgggaa
    10681 agcaagcaga tattggaaat atggtgtttg tttcgtcaat ttgatttcta attcatagtc
    10741 accaactgct ttgatcccta gttctgattt atctttcttt ccagctgtaa tgtcttctgc
    10801 attttcaact ggcgcataca ggtaagcata ttcagaagct gtagctgggt ctactgttcg
    10861 ttgccagcca taaacgtaat ccgctgctgt aacaggatca ccatttgacc attttgcgtc
    10921 ttctcgtaat ttgattttgt aagttaatcc gtcttcactg acttctgcca actcgctagc
    10981 tcctgccggc tgtggtttgc tgtcttcatc aagacggtaa attccttcat aaacgttatt
    11041 caatgctgta aaactgattg tatctgttgc aactgataag tcagctgtag gcatttcttg
    11101 aggcacgact aagttaaata cgcctcctcc atctgctgaa ccgctttttg ctgaactact
    11161 gcttgtggct gaactgccgc cataacatcc agcaagtaca aggccgcata ccgcaaccaa
    11221 accaaatgta aatttctttt tcattttacg taccccttta ttggaatttt cagaataatt
    11281 aatattttct gaagttgttt aagagtttaa tgaataatt
//
LOCUS       DAZKCW010000070        11148 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000070 DAZKCW010000000
VERSION     DAZKCW010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.072"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..305
                     /locus_tag="ACG84Z_002284"
     CDS             6..305
                     /locus_tag="ACG84Z_002284"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9163089.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACG84Z_002285"
     CDS             378..1739
                     /locus_tag="ACG84Z_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFP9163090.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACG84Z_002286"
     CDS             1761..2021
                     /locus_tag="ACG84Z_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163091.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACG84Z_002287"
     CDS             2035..2787
                     /locus_tag="ACG84Z_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFP9163092.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACG84Z_002288"
     CDS             complement(2881..3486)
                     /locus_tag="ACG84Z_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9163093.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="ACG84Z_002289"
     CDS             complement(3542..4516)
                     /locus_tag="ACG84Z_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFP9163094.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIK
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5613)
                     /locus_tag="ACG84Z_002290"
     CDS             complement(4894..5613)
                     /locus_tag="ACG84Z_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9163095.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACG84Z_002291"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACG84Z_002291"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFP9163096.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="ACG84Z_002292"
     CDS             7164..8561
                     /locus_tag="ACG84Z_002292"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9163097.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="ACG84Z_002293"
     CDS             8642..9082
                     /locus_tag="ACG84Z_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFP9163098.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="ACG84Z_002294"
     CDS             9229..9555
                     /locus_tag="ACG84Z_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFP9163099.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="ACG84Z_002295"
     CDS             9556..10305
                     /locus_tag="ACG84Z_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFP9163100.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="ACG84Z_002296"
     CDS             complement(10331..10741)
                     /locus_tag="ACG84Z_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFP9163101.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3536 a         1947 c         2291 g         3374 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagttttgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaatt
//
LOCUS       DAZKCW010000071        11140 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000071 DAZKCW010000000
VERSION     DAZKCW010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.073"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            222..1382
                     /locus_tag="ACG84Z_002297"
     CDS             222..1382
                     /locus_tag="ACG84Z_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFP9163102.1"
                     /translation="MKITEKNVNPKFEPTESNQKMFDLTVTLSNQLVDSIVEMDAMPQ
                     KIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSSSSKHSRLKQVIEKLHQQSVIK
                     IQRTKTNGKTEYKVISPLEITEFNDFSDAVSIKFSSSIMPLLTNLEDHFTQYTFDQLV
                     NLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDRLKNPVFSIAELRKKFSIEKKY
                     KAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTYTDIKFLLTRTMSVPVPYKQEQ
                     RDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFLISSADLCDLKFMSRLQNKVYP
                     LYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYLEKSITSYLPYVNLYD"
     gene            1418..2185
                     /locus_tag="ACG84Z_002298"
     CDS             1418..2185
                     /locus_tag="ACG84Z_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFP9163103.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LKIDFAKVRKGRNYNFAVQFNISSEFDEKPYREKKLG"
     gene            2377..2775
                     /locus_tag="ACG84Z_002299"
     CDS             2377..2775
                     /locus_tag="ACG84Z_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFP9163104.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(3083..3457)
                     /locus_tag="ACG84Z_002300"
     CDS             complement(3083..3457)
                     /locus_tag="ACG84Z_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163105.1"
                     /translation="MKQTQTETVNDTLADQLAGYYKLFEMSKAQRLIHYLWKYKILFL
                     FWEATLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTFITLEENLVISDAGIERN
                     IKRVSIKITLNKPTDKKLSEAF"
     gene            complement(3479..3829)
                     /locus_tag="ACG84Z_002301"
     CDS             complement(3479..3829)
                     /locus_tag="ACG84Z_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163106.1"
                     /translation="MKATHLNYFSRTLINNLLKDTTGISVSTKHFANDLIIFEDNNLR
                     IEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKKAKLLFEFQT
                     DYHNELLAQSEILD"
     gene            complement(3846..4241)
                     /locus_tag="ACG84Z_002302"
     CDS             complement(3846..4241)
                     /locus_tag="ACG84Z_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFP9163107.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            complement(4308..4493)
                     /locus_tag="ACG84Z_002303"
     CDS             complement(4308..4493)
                     /locus_tag="ACG84Z_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFP9163108.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            complement(4575..4829)
                     /locus_tag="ACG84Z_002304"
     CDS             complement(4575..4829)
                     /locus_tag="ACG84Z_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163109.1"
                     /translation="MNYTDEEQITLEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            complement(4851..5096)
                     /locus_tag="ACG84Z_002305"
     CDS             complement(4851..5096)
                     /locus_tag="ACG84Z_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163110.1"
                     /translation="MWTLEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTS
                     LECVWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            complement(5103..5387)
                     /locus_tag="ACG84Z_002306"
     CDS             complement(5103..5387)
                     /locus_tag="ACG84Z_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163111.1"
                     /translation="MLKATLQQPTHVAIAESYTINAGVVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKNSFIGKLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            complement(5878..6363)
                     /locus_tag="ACG84Z_002307"
     CDS             complement(5878..6363)
                     /locus_tag="ACG84Z_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163112.1"
                     /translation="MGWYGAYSSANEVIEEKKGYAKNGLEIVDTKVTKTYGIILFKDA
                     EGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFFVGDQEKMVKRQLDRIKEE
                     SNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQDGSLTRFTRLSAGDVKEV
                     A"
     gene            complement(6530..6796)
                     /locus_tag="ACG84Z_002308"
     CDS             complement(6530..6796)
                     /locus_tag="ACG84Z_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFP9163113.1"
                     /translation="MSYQVRYEREAQKTLKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            complement(6798..7019)
                     /gene="relB"
                     /locus_tag="ACG84Z_002309"
     CDS             complement(6798..7019)
                     /gene="relB"
                     /locus_tag="ACG84Z_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFP9163114.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKELMKEHEENDQSISHEDMLKELGL"
     gene            7257..8075
                     /locus_tag="ACG84Z_002310"
     CDS             7257..8075
                     /locus_tag="ACG84Z_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9163115.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            8088..8375
                     /locus_tag="ACG84Z_002311"
     CDS             8088..8375
                     /locus_tag="ACG84Z_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163116.1"
                     /translation="MKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAKLKS
                     DSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(8557..8910)
                     /locus_tag="ACG84Z_002312"
     CDS             complement(8557..8910)
                     /locus_tag="ACG84Z_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163117.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(8930..9985)
                     /locus_tag="ACG84Z_002313"
     CDS             complement(8930..9985)
                     /locus_tag="ACG84Z_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163118.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            10201..10599
                     /locus_tag="ACG84Z_002314"
     CDS             10201..10599
                     /locus_tag="ACG84Z_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163119.1"
                     /translation="MQLRRNKNYTTIILEDFTDQELLIVGKTKADFIKKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKELYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            10602..10775
                     /locus_tag="ACG84Z_002315"
     CDS             10602..10775
                     /locus_tag="ACG84Z_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163120.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHLFIFAYILAMIA
                     FLSGGWLIIYLLS"
BASE COUNT         3679 a         1741 c         1910 g         3810 t
ORIGIN      
        1 ttttattttg taaaggttct aaaatagcga tttctgctgt cttatcaatg aaatttgatt
       61 aataaaaata aaatgcgttt tactgagatt gagttatgtt ataaatttac gatacatttc
      121 ttattgtatc gtatcgaaaa caggtctata cttattcaat ggaatcgtac cagttccaag
      181 tttttaagct cgtaccaagc ttagaaagaa gaggcaatcg tatgaaaata acagaaaaga
      241 atgtaaaccc gaaatttgaa cctaccgaaa gcaatcaaaa aatgtttgat ttaactgtta
      301 ctttatcgaa tcaacttgta gatagcattg ttgaaatgga tgctatgcca caaaaaattt
      361 atctttacgc tataggacat cttgacccta aaaatccgcc ttttaataat accgtcaaag
      421 tatctaaaaa ggctttattt gcgttgatgt cttctagttc atcttcttca aaacattcaa
      481 gattaaaaca agttattgaa aaattgcatc agcaatctgt cattaaaatt caaagaacta
      541 aaactaacgg taagactgaa tacaaagtca tctcaccgct agaaattact gaattcaatg
      601 atttttctga tgcagtatct attaaattta gtagttcaat tatgcctttg ttaacgaact
      661 tagaggatca ttttacacaa tatacatttg atcaattagt taacttgaca agcaaatatg
      721 cgatcagttt ttttcaatta ttcactaaag attttaatct gtatgaagca aatagagata
      781 acttaacatg gagtacaaaa tcacttgata gattaaaaaa ccccgttttt tcaattgcag
      841 agttacgaaa gaaattcagt attgagaaaa aatataaagc ttttcgagac tttgaaagac
      901 gtgtaattaa agaaccgatt gcccaactga ataaatacac tgattttaaa attgactatg
      961 agcttatcaa gaagggtcat acttatacag atataaagtt cttgcttaca cgtaccatgt
     1021 cagtaccggt accttataag caagaacaaa gagaccctgc ttatttaaaa ggcgcagaag
     1081 ataaaacaga gaaaatgaat caatcgtact tgaaagctat gaatagcaaa tacactaaat
     1141 tactaatcaa aaactttttg atcagttctg ccgacttatg cgatctgaaa tttatgagtc
     1201 ggcttcagaa taaagtttat ccgctttatg atcgtttatc caaagataga ggatttgaat
     1261 cagttgtcaa tcatctatct tacgttgcta ctcataagga ggattacaca ataaaaaata
     1321 ctgttaaata tctcgaaaaa tcaattacga gttatttacc ttatgtgaac ctttatgatt
     1381 aacaactgaa aaacttgcgt gaaggaagga aaagcttttg aaaaaagatg aactgacaaa
     1441 gtacaacgag gagttcttag caacaattga catgaaaatg gatttaaagt cgtatgaact
     1501 ttatcaattg ctgttcagtt atatctcgcc cacaaagcta aagaaaacag gcgtagtaga
     1561 tttacctgtt aaagcgatta ttaattacat ggatgttgat caaaatcttg aaactgaact
     1621 aaaaaccata gttaacactt tgcaaagaca agcagtttat gaaatatcga atctagacaa
     1681 gaaatataag acgtatacaa ctgtatctgc tattgatcgg attcattggg atttagaaga
     1741 gcatagtgta tctttcagtt tttcagaaga tgtaattccc ttaattgtct caatcaaaaa
     1801 gaagtatccg ttctttgttt ttgaagactt agcatctttt caaaaaaaat atagcatcgt
     1861 gttatacaaa tatttggcga tgtattataa aaaatatctt atcgccaaaa ataaaggaga
     1921 ttttgagaaa gctgaaatat ataagaatcc cctgattgaa atagttaaaa ttcgtgagat
     1981 tacgaaaaca gaaaatgagt ataaaacaat atcgaatttt gatagacgtg ttttaaggga
     2041 atcagttgag gaaattaatg aaaaatcaat gctgaagatt gattttgcta aagttagaaa
     2101 aggcagaaat tacaattttg ctgtccagtt taatatttct agtgagtttg atgaaaaacc
     2161 ttatagagaa aaaaaattag gttaatgcaa aatatatctt actcgtttga agatgcttca
     2221 gacgtatgct aagatatgta gtgccttggg agcaaggtat taatctcctt tagaggttaa
     2281 ttagcttgtg atcgcctatc aatttttttg gtaggcgatt cttttttttg aaactaaaaa
     2341 gcaaaaatta ttttttaatt agagaggtgc aatgcgatga aatacttttt ttgtgcagta
     2401 ttcgaatgga aaggaaatga atatgcagtt aaattcccag attttccaga cttatatacg
     2461 catggtgaaa ctttagaaga tgcttttgag atggcgcaag aagtattgga aggatacttg
     2521 gtgcttttag agttgcaaga aaaagaaatt ccatcgccta cgcctgttca agagttaaat
     2581 gcaagaatca agcgatctga gaatgttaat ttatttgtcg taaaagctaa tacgaaagtt
     2641 gctaaagctc gaaacaagca aaattacgat cgaaaatcag tgactgtgga acactattta
     2701 aatgttttag cggctgaaga gaatattaat ctgtcgaaag ctttgaatga tttgttgaga
     2761 gaaaagttga tttgatgtct ctcaaatgat catattaagc aataacagct tgttttagga
     2821 cgtatggatt taagaaagac aaattatcaa agaatatatt aaaagctctc agaacgcttc
     2881 tgagagcttt taaattgcta tgtattatac tgcatctgct caaattgatt ttcttttcat
     2941 gcttaccatg tatctagttt tccatcaagt aatttttaga tatgtattga gtaataaata
     3001 gcaaatttgc ttgatataag ctcgaattag gtgctttgta atgtgttagg ataaatttta
     3061 tacaagcaaa tgtcaaaagc tctcagaacg cttctgagag ctttttatcg gtaggcttgt
     3121 ttaacgtgat cttgatagat acccttttga tgtttctctc gatccctgca tcgctaatta
     3181 ctaagttttc ttcaagtgtg atgaaggtat ataaattaag catcaaaatg gtgtagataa
     3241 gcaaaaaact ccctaaaact aagtgttgat tataaaaatc tgacttataa aaaagaactg
     3301 agaatgttag tgttgcttcc caaaaaagaa acaaaatttt gtatttccaa agatagtgga
     3361 tcaagcgctg tgctttactc atctcaaata atttataata acctgctaat tgatcagcaa
     3421 gcgtatcgtt aacggtttct gtttgtgttt gtttcatctt tctcttctcc tgtttcaatt
     3481 aatctaaaat ttcagattga gcaagcaact cattgtggta gtcggtttga aattcaaata
     3541 acaattttgc cttcttaacg aggtttaaag cgttcgttag tgattcactt aatgcttcaa
     3601 catctttaac tgattttgca tgtttcattt tttcagtgtg cgtatagcag aattcaggta
     3661 ttgagttagg ggttgcctgt tcaataaaca tctcaattcg caagttatta tcctcaaaaa
     3721 taattagatc attggcaaag tgtttggtac taacgctaat gccagttgta tcttttaata
     3781 gattattgat taacgttcga gagaaatagt ttaagtgtgt agctttcata ggttcggtct
     3841 cctttttact tttcaagcaa ctcttcttct agtgcttttt gaagtagttg agagaagttt
     3901 atgtttttct ccttccctaa aagaactaac cattccggaa cactaacatt ttttctaatt
     3961 gtttttgtat ttaagcttct tcggaaaagt ttaatgttta gttggatgat tactaccact
     4021 tggttggctt tcaaagttaa ttcttccact gctgatggtt taggaaattc tgcatctggt
     4081 acactatata gcgctaatcc taaagcatcc ttagcgttta aatatgcttc ttcaagacta
     4141 tttccaaagg tagatatttc cggtaagtca gggaaaacga tgttataagc ttctccttct
     4201 ttctcgaaga ttgccggata aaaaatattt tttgtcttca tttcctcgct ccttttctag
     4261 tgtaagagag gatagtatgc ctaataccaa ataggaaggc aaggctgtta aagccctgct
     4321 tgcttccaga tattagcttc tgttcctagt ggtacatcac cattgtggat cggaacaacg
     4381 accgttcttt tagtcttgga attataaaat tttgcatgac tgccagtttg tccagtcttt
     4441 ttgaagccgt tagatttgag aatttttaca atttctcttg ctgtcttagg catagctacc
     4501 ctccctttac aaaatctatt atacacattg ttgtgtatgg aatcaataga aaaagaggat
     4561 gttttattgc aaaactaata aaatgattta ttggtttttt cagcaaattg aatgttatta
     4621 gcgttgcaaa tattcataat ttcccaagta tcattagaag tataggtatc taagaattca
     4681 atgacagtta cggttgattc gtatggttca taagccaaag ccttctccaa gtcttttgat
     4741 gaaatgatca agactttttc aatttcctcc ccttcttcat ttgtgaaaac gtattccaaa
     4801 gtgatttgtt cttcatcggt ataattcata ttgtgttctc ctttcttgta ttaagaaaaa
     4861 tggatatttc caattgcatc ccactcggca ccattgtggt ataagacgtg accgagcgtt
     4921 acgcctttga aatgctcttc taaatacatc caaacgcatt caaggctagt acctgctttg
     4981 agattgtaga agtctgcatc caataccttt tcagaagtta tcggatcaat gcgagttggt
     5041 acctcaataa attcagtcca aatttctgca aaagtcttac cttccaaagt ccacactccc
     5101 tatcaattaa ttccaaaagc aaatagagaa atcaagcgac cgtcaatagt cacttcaaca
     5161 actgaaaatg ccgttgaaac agttttaaca tccacacttt ccaatttccc gatgaaggaa
     5221 tttttgtgct ttagaatagc tttctttaac tgtctgttat acgcttgacg actgttaaac
     5281 tttttgaatt ctcgatcctt gatcagctgt ttaacgaccc ctgcattaat tgtatagctt
     5341 tctgcaatag caacgtgagt aggttgctgt aatgtagctt ttagcatatt gtcattcctt
     5401 cctaaaagtt aattagcttg tttacaatta cattatacac actagtgtgt ataatgtaaa
     5461 gagaggtttt ttgctgatgg atcagctgtg ctaaacaaaa gaaaacgata gagtaacaaa
     5521 aaaagtcagc aaagttaaaa aggatgaaac ggctagtccg gttgctttgc ttgtgtaagt
     5581 ttcggctttc ttatagatca aataggaaat tataagtgat attccagtaa agaataatgt
     5641 actagctgtc actaaaagaa ataggttaat catacgatac actccttctg taatattggt
     5701 atcagatacg tttaaatgcg tttctgagct gttttggatc agatggtgat gttttagccc
     5761 taccctaaaa tcaaagccca gaaaagcatt taaaagcgtt cgtacctaat acgtttatat
     5821 tcatatacat atacataaac ataaacgtat acacgtttat gtttatgtat ttaagtttta
     5881 ggctacttcc ttaacatctc ctgctgatag tcgagtgaac cgagtgagtg atccatcttg
     5941 tagtcggaaa ataaagctac gtttgagttt atactgataa acagcgacat acgatccatc
     6001 ccagattgag taagttttac ctgcaactaa taagtcatca agttttggtt tattgctttc
     6061 ttctttaatt ctatctagtt gtcgcttaac cattttttct tgatcaccga caaagaattt
     6121 caaccatttt tttggaattt tcttaaagta agcaggactg tcatttaaga agtagattgg
     6181 tttgtacatt tcatctcgaa agatgaagct gtcaatatcg taggttcctt ctgcatcttt
     6241 gaaaaggata attccatagg tcttcgttac tttggtatct acgatttcca aaccattttt
     6301 ggcgtaccct ttcttttctt cgattacttc atttgctgat gaataagcac cataccatcc
     6361 cataaaaaat cgctcctttt gaaagttaat tagcttgttt acacttatat tatacacact
     6421 ggtgtgtata ataacaagag gatattgttc ttttttaggt aaagtgggat cgtaaacagt
     6481 gattttgttg ggttaacaaa aaaacagaca agccttatca gcttgtctgt tacttataaa
     6541 cttcacttct gtgaccaata gacaatataa gaattgtcac ttcatgctcg ctaatatcag
     6601 ctattatacg gtatgcacct accctatatc gccagtagcc tgatttatta gctgttagac
     6661 ctttaccatg ctttcttgga tcatcagtgc ctacaagatt tttctcgatc cagtttagga
     6721 taacctttgc ctgaaactta tccatttttt ttagcgtttt ttgagcttca cgttcatatc
     6781 ttacttggta actcatctta taagcctaac tcttttagca tatcttcgtg ggaaatactt
     6841 tgatcgtttt cctcatgctc tttcattagt tccttgtagg tagcaaagtc tactaacgtt
     6901 tctgctgttt gcagggaatt actacgcata aattcagaaa tgttatctcc gttgaattca
     6961 gcaacttttt caagaaaatc tttttcttct ttagatacac gaatacttat tactggcata
     7021 gtttatcaac tccttttcaa ttacattgta ctacgattgt atgacagatg caatagttat
     7081 atatatgaac atatacataa acataaacat atacataaac atatacatat atatgtttat
     7141 gttatagaat ataaaagcaa atataaatat aaacaccttt atgtatataa acatatacat
     7201 aaaggtgttt atagtgtata atggagttac aaaaggttaa taagggaggt ttaatcatgg
     7261 aaaagaagtt gtcaatcatt actggaaaca ttgaaaaagg tggaacaggt aaaacaacaa
     7321 caatctacaa tctaggtgga tatgctgtcg aaaatttagg tatgaaggtg ctgtatattg
     7381 atgaagataa gtcgcaaaac ctatcaaaac gctttcctga tgctttcagt aaagcgaaaa
     7441 gagagaatac aatcaatcat ttatatcttc atggatcagc tgaaccttta gctataaatg
     7501 agaacatgga tattttagta gcaggtgaag atttaaaaca agttgagatg caaatgcgtg
     7561 atatgcctaa caacagaacc ctactgttta gatggatcgt tgttaactat gaacagctta
     7621 aagagaagta tgatctaatt ctgattgata ctcataatga tgcaggtcta ctagctcaaa
     7681 atgcttgggc tgtatctgat cttgtcgtag gcatttctga tccatctaaa gatggttttg
     7741 aagctttgct gaagcttggt aaagatattg atgcactagc aaaacagttg attgatatta
     7801 agactggtga aacactgatg gaaactaaat acgctacgat cggtagcagg atcaaacata
     7861 atactaattc aagtcgtgag ttcctagaat tggtaccaac gttatctaat tatcttggat
     7921 atgtacaaga gaaggaattg cttaatgcaa ctagcttaga aggtaagaat attgctgagt
     7981 tcgctaagga taagaatatc tatcgtaaga ataaggattt ctttgaaagc acgtttacgc
     8041 tatacaacaa gataattgat acggcacaag aataaggagt gattgaagtg aaagaaaata
     8101 gatttaaaaa attcgctgaa gctgaagtag aagaagttcc tgaagtggtt gaagcagttg
     8161 aagaacctaa acaaacacct aaagaaacaa caagttcttt ggtagctaaa ctaaaaagtg
     8221 atagttctga aaagaagaaa aattatcaat tcacgcttca accatcgcaa agaaagaagc
     8281 tatctaaaat cagcgaaaag ttaggaattc gatcagattc agctttactt ggtgaaatga
     8341 tagataactt gtatgatgaa gtttttggtg agtgatcagt ttaaagctga tcactttttt
     8401 tattggaata agcggttagg tatagcttaa ctaaatttca tatacgtgtt tatggatata
     8461 tacgtataca tgtttatata catgtatacg tatatgttta tgtttatatt tgtacataat
     8521 aaaaaggcta ggtattgtaa cctcgccttt ttcattttaa agtaagtctt tgttacttgg
     8581 tgcattgaac ccttttagca ttggcttttc tttctttgct gaatgatcgg atgtaaccgt
     8641 tgaaggatgc tcttgttgaa tagggttatg atcagttggt ttattcttta cttctgctac
     8701 tttgctatcg tttctatcgt tgcctgcttc aataattgta acttcattgt tctttacacg
     8761 ccgatatagg ttcaaagctt ttttgatcgt ctgagagtat ttaacgccta gtgtttcata
     8821 ttcggattca agaaactctg ctaaaggtaa ctcgctaacc ttttctctat tgattataac
     8881 tacataacgc tctgattttc ccttattcat gttgatctcc ttcgctgttt tattgagtta
     8941 aaccaaactt gtaaaagcct tttacattag aaaattcact gtcttcaaca aacaaggtat
     9001 gcggaatttt atcttttaca agttgtttgt cgataataga agctccacca ccagtaaaga
     9061 caactttatc taaggtcgtg aagtttttga atgtagctaa aacttctgca acaaccatat
     9121 ttgtgtatgt ttttatttct ctttcaacta cttctgaaat atcaaaactt tcatttccgc
     9181 ttggcttaaa tagatatacg cctttttctt tgccttctcg gataatcttt tcaagttgga
     9241 aagcattagg actgatcgga aggtcaagca tatttacgat acgattatat aaagtaaaaa
     9301 tgccggtatc cttttgttca cgattgtttt cgtcaatttc aaaattttgg acaacatcaa
     9361 aaagtttcgt gccaccacca atatcaacaa aaccgatctt ctgactgatc aaggtttcat
     9421 cttgtacgct accatcatca gcaagtagga ggttatatag cgttccgatt ggctgtggca
     9481 gtacccaaac ggtatctacg tttatattat aagccttacc gtcaacttca actgaatgtt
     9541 gtcgtgtggc ttgttgcatc acgtatttga cgattgtttc ggtatagtcg gatgaaggca
     9601 gacctaaaac tagattaacg gttaaaacgt catcagattg atcttctaaa cgtgctaggt
     9661 tagctaaaga gaaagatagg atattttggt aggtttcctg cttgtatctg ctaatcccaa
     9721 aacctagtga ttctatcacg tagtcatctt ttcctagctc gtgtatatcc ttcccaaagt
     9781 aatagctttc agtagtgttt actaggctat attcagaaac gtttagtgat cgttttaatg
     9841 aggaacctat attagaaaaa cgtcctgaat taatgatatt tttgttcaaa atacgagagg
     9901 gaagtgagag tggagaaacg tgggtactca tttcttttac tgatttattc cctaagtcaa
     9961 cggaaaacaa taatggttct ttcatggtat gacctctttc tgtttgtgtt tatggtatct
    10021 cggtacgaaa atagtttaca cctatttact attagttgca actgtttata agaaaaaaat
    10081 gcaatcataa aagtataatt aattataata aagtgtaaat aaaaaggtgt aaacaaatac
    10141 ttgtaaattt atcttattat gatattataa aaacataaat tatattaagg agtgatcctg
    10201 atgcaattga gaagaaataa gaattacact accattattt tagaagattt tactgatcaa
    10261 gaattactta ttgtcggtaa aacaaaagca gattttatca aaaagggaaa tgcttcaata
    10321 gtaaaagctt caaaggttgc tgtcgaaaaa tattttgatt ctttagaaga aagtgctaag
    10381 gaaattttta atggagagaa agctggtagc tatgagttag atggaattag atttagcttg
    10441 atcccaacaa ctgaaaatat tattccaaag gaattatatt atatcttttc atctgaaaaa
    10501 catacttcaa tgaagccttg tatttttgat tggcaatggt tgattgatgc tgtactggat
    10561 gtaaaatgtt caaaatacaa tattactttg gggtgttaat tatgagtatg ctagttagaa
    10621 aattaccatt atcagtaaga gaatttctat tttacttggt ctgcttaatc gcatcagggt
    10681 ttaagctgat cgaacatctt tttatctttg cttatatatt agcaatgatc gcatttttat
    10741 caggcggttg gctgattata tatttgttaa gctaagtttt agatcaagaa taatcaacag
    10801 attaaatgat taaataacct atgaaaaatg taatttaagg acaatgccta acaagcagac
    10861 tgtattcggg ttataaaata acgcaattta aaaatcagtg ctttttaaag gacaaattaa
    10921 gtgtatcaac ataaacgtgt atatgtatat gtttatgttg atactttttt tgtcttactt
    10981 tttttatttt taaaattcta tttgttaatg ctgtgtagat aatgatcaga aaaaacaaaa
    11041 tagcgaggtt aagctattta ttagttcata tattgtattc agattaatat gatccagtat
    11101 taatctgaag gcgaaaccaa tatatttcta cgatttcttg
//
LOCUS       DAZKCW010000072        11114 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000072 DAZKCW010000000
VERSION     DAZKCW010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.074"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            137..310
                     /locus_tag="ACG84Z_002316"
     CDS             137..310
                     /locus_tag="ACG84Z_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163121.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            950..1423
                     /locus_tag="ACG84Z_002317"
     CDS             950..1423
                     /locus_tag="ACG84Z_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFP9163122.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1432..1659
                     /locus_tag="ACG84Z_002318"
     CDS             1432..1659
                     /locus_tag="ACG84Z_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163123.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2295..2666
                     /locus_tag="ACG84Z_002319"
     CDS             2295..2666
                     /locus_tag="ACG84Z_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163124.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2922..3164)
                     /locus_tag="ACG84Z_002320"
     CDS             complement(2922..3164)
                     /locus_tag="ACG84Z_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFP9163125.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3196..4098)
                     /locus_tag="ACG84Z_002321"
     CDS             complement(3196..4098)
                     /locus_tag="ACG84Z_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFP9163126.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4111..4299)
                     /locus_tag="ACG84Z_002322"
     CDS             complement(4111..4299)
                     /locus_tag="ACG84Z_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFP9163127.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="ACG84Z_002323"
     CDS             complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="ACG84Z_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFP9163128.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4914..5807)
                     /locus_tag="ACG84Z_002324"
     CDS             complement(4914..5807)
                     /locus_tag="ACG84Z_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFP9163129.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5885..6808)
                     /locus_tag="ACG84Z_002325"
     CDS             complement(5885..6808)
                     /locus_tag="ACG84Z_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFP9163130.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6857..7207)
                     /locus_tag="ACG84Z_002326"
     CDS             complement(6857..7207)
                     /locus_tag="ACG84Z_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFP9163131.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7240..8142)
                     /locus_tag="ACG84Z_002327"
     CDS             complement(7240..8142)
                     /locus_tag="ACG84Z_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFP9163132.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8135..8992)
                     /locus_tag="ACG84Z_002328"
     CDS             complement(8135..8992)
                     /locus_tag="ACG84Z_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFP9163133.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9326..10135
                     /locus_tag="ACG84Z_002329"
     CDS             9326..10135
                     /locus_tag="ACG84Z_002329"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9163134.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10175..10672
                     /locus_tag="ACG84Z_002330"
     CDS             10175..10672
                     /locus_tag="ACG84Z_002330"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFP9163135.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
BASE COUNT         3249 a         2082 c         1868 g         3915 t
ORIGIN      
        1 tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc gttcttactt
       61 tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc ttataaataa
      121 aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa cgattggcta
      181 tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat tcagttggac
      241 tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac aaaattatcg
      301 aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta tggtactttt
      361 tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac ttttgattta
      421 taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga tagtaccacc
      481 ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata aaggacaaat
      541 aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa taaacatgaa
      601 cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct catacagttc
      661 tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta ttgtccaata
      721 taatcccagg catctaaact agcattatag aagagacaca catagaatct aaaataactg
      781 gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac cttcatactc
      841 tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag ttgttttaca
      901 ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa tgaaatttaa
      961 aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt tgttcggcgt
     1021 acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt ggcagaccac
     1081 attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg cttatttctt
     1141 attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa gcttaaacat
     1201 actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg gcttacttcc
     1261 taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg taggaatcgc
     1321 tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa aactgcttga
     1381 acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga catggcaatt
     1441 atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga attgagtgag
     1501 aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc aaaagccatc
     1561 cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg tgatttgttg
     1621 acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga acaaacagta
     1681 aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt acgtctatta
     1741 ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat gtactgactc
     1801 atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca actggtttcc
     1861 tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca ccagactgat
     1921 agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt tcataccttg
     1981 aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat tcttttttag
     2041 taagctccca tatatactgt aaagccttct atatattatg tcatgttgct ttttaacatt
     2101 tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct tttttatttt
     2161 taacattatt ttgataataa tgattattta tttaaaaata cattagataa catttgttac
     2221 gacacgaaaa agcttcacaa acaaatatcg ttattttaaa atgagggcga actcacacaa
     2281 ttaggaggaa tagtatgcca tttattgttt acttttttct ttcattactc gtgatctata
     2341 ttccattacc aacatttttc ctgctcgtca atcgtctagc agagcaacat gatacgattg
     2401 ctgctcttac gaaactttgt ttacttctat ttgtttgtct agattacttt acgagctatt
     2461 attggctaaa acagacaaga gtaaaaaaga gatattattt cttccttgtc tttttcaatc
     2521 tctttgagtt tctgatccat tgctttttac ttcatcagta tcatacgatc catttgtgga
     2581 tcatctgggt tttcaaagtg gtcgtattat tttgtatgtt cacctttcct atctcaagaa
     2641 aatttaggga ggcattgttt tattaaagaa gcttctctgt atcaataaag acacatttaa
     2701 ggaaaaactt ttaaaaatct aattgggaat ttgcccgcat aaataagagg ctgtgacaaa
     2761 agtcttgtca cagcctctta ttccgtataa acagtgttca aaagcttgca tcttcgataa
     2821 tatgcccaac caaatgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
     2881 atgaagaaca gctttttcac gacctctttt taaaagtctt tttacagttt tcgagcaaag
     2941 aatgatacga ttagtactaa aatgatggca ccaatcaatg atggcacgat tgccattcct
     3001 gcaatacttg gtccccaaga acctaataat gcttgaccaa gtgctgatcc aactaaacct
     3061 gctacgacat ttgcaataat ccccatcgaa gaacctttat tcgtgattgc tcctgcaatt
     3121 gctccgataa ttcctccgac gataagtgac caaataaatc ccatgtttcg ttcctcctaa
     3181 tgttttactt ccttattact gaacccgtgg ttctgtattt tcttttactt tttgtgcgcc
     3241 gcttccagct gctgatttta ctttatctgt ttgattcgaa gcaaattcac cggttttttt
     3301 cgctgcgtca gttactttgt cttgcaccgt ttcttgatct ttttcaaatt cttcttttgt
     3361 tttgatgtcc actacgttag cgttgacttc gatcacttct aaatgtgtca tattttttac
     3421 ttctttgccg attacttctt gcatttcttc aaagattttt tcgatatctt tgccatattc
     3481 cacaatgaca tccatatcaa ctgctacttg ttttttaccg acttctgttt cgatcccagc
     3541 cgttacatta tctgtattca caagttttcc tgccacatta gagaagaaac caccgtttgc
     3601 agataataaa ccgtctactt gttcaattgc gattccgatg attttttgca caactttatc
     3661 ttcataattc agctcaccgc gcattgaatc ttcctgttca gaatcatgct ttccttggtt
     3721 atttgtatga tcagaaccaa gttttccttg tccgtttgtg tggtcagaac taagtttttc
     3781 ttgtgctttc gcatggtcag aaggatgttt ttgctcttcc acaggtttag aaggatcgat
     3841 tgcatcatgt tgttctggaa ctttagattc tggagttcct ggatgatgag gtgcatgctt
     3901 ttctgcatca tgtttcttct cttctactcc ttgttgaacg ttagggacta ctggatctgg
     3961 atgtgcagat actggtgctg ttttgttctt ttcatcgttc acaccatttg attggtttgg
     4021 tgtcgttggg tctggatgtg cagacactgg tttttggttg ttcattttat tgttattatt
     4081 tttgttattg ttattcatgg atgtttcctc ctaagattta aaatagtgat ctaagatttt
     4141 cgtttgtttc agataaaaac cgatagcgac gccgatcgct gccatgatca agatcaataa
     4201 ggtcttgaaa aagcccacgg tgatccataa aacggctaat atcaatccaa gtaccccaaa
     4261 gatgataggg agcttgtatg tcgaaaatag ttctttcatt tttggtcccc ccctattcta
     4321 ctcgtttgcg gtcattgctt cgtttagctg gttcttcaaa gcctgtgtat ttcaccgata
     4381 ctttcactgg ctcttttgtt cccaatatgt gttgtacttc attttcgatt tctttcatca
     4441 atgttcctgt tttaccaatg agtgctgaag ttcgtttcaa ctcccctttt acattgacgg
     4501 cgatcttgtt tttcgttgct ttgacattta cttttggtga atggatgaat tcatcttcat
     4561 gcaagtgaga acgaaccatt ccttcaattg cttttttatc caacgtcaac tccccatcac
     4621 catgtttcag tagaaagttt ccgattgttt ttggataaaa caggaaaaca agtaacgtga
     4681 taattgtcaa aatagcaaat gcaacggcaa gccaaaatac atattgttgc acgtatgaat
     4741 tagtgatgga aaagaatcga aacttctcta gctgaaaagg caatggatag gttgcactta
     4801 atagtatcgc aaacaaaagc acagatagca aaagtaatgt tccgatcact ccgatcgttt
     4861 ttacaccttt attcattttc gcacctcctc ataggggtga aacgatcaac ttcttataag
     4921 ttgatcgctt ctccaccagt tactccgtaa atttgggctg taacataact tgctttattc
     4981 gatgctaaga aaacataaac tggtgctaat tctcctggct gacctgcacg ttctagtaaa
     5041 ctttgctgac caaattcagg gatcgaatca gaaggttgtc cttcgtctag ttgtaatggt
     5101 gtccagattg gaccaggtgc tacaccattt acacggattc ctttaggtgc aagctgtttt
     5161 gctaaaccga tcgtaaagtt agcgattgaa gcttttgttg ctgcgtaatc taataaatgt
     5221 tcgcttggat tgaatgcttg aacagaagtt gttgttacga ttgctcctcc tgctgggata
     5281 tgcggaacag cttctttcac taaagcaaac atagcgatga tgtttatcat aaatgtgtct
     5341 ttgacttgct caagtggtaa ctcagcaata gactgacaag aaatttgctg tcctgcgttt
     5401 agtaccatcg tatctagccc gccaagttca ctcacggctt tatctatgat ttctttaggt
     5461 gcttgttcgt cacgaagatc aaaaggtagt aagacaatct tacgtcctgc aactttcacg
     5521 tattttgcta cttcctctgc atctttttct tctcctggga agaattgaag agcgatatct
     5581 gccccttctc tagcaaatgc aatcgctgct gcacgaccga tccctgaatc tccaccagtg
     5641 attagtacac ggcggttttc tagttgatta ttgccttcat aggattcttc tccacaatca
     5701 ggaacaggaa tcatattctg ctgtaaagct ggtgtatcct gatcttgttt aggaaatttc
     5761 tccgtatggt acaagtttcg cgggtcgatt aattttggtt ctgtcattgc tgtattcctc
     5821 ctagttttta aattgtattg ccaaaacaaa tttctttgtt tgatacctgt tttaaataga
     5881 ttctttaatt tgtataatct ttccggtata aatggtaacc taaaactact gctgctatca
     5941 aagagccaaa gactacgagt ataaagccta gagcagaact tttacccggt aatcctcctg
     6001 tattcattcc ccaaatccct gcgaacaacg ccggaacgga aatgattaat gcagctgaat
     6061 ctagatattt catgatatga tttagattat tgtccatcat cccgttgaat agatcaccaa
     6121 tactctctaa taaatctcga tagatctcga tcattttttc tgtttgtcgc tgtctcaaat
     6181 ggacatcata gagtagctgt tcatcgtcta aacgtttgat gaaagtttca gaattccata
     6241 attgatccat tgtttcccgt tgatctctta aggtatgatc gatatatacg atgtctcttt
     6301 caagatctgc ctgtttatac agttcttcat tttccgttgt tttacgagct gctttatcca
     6361 aagcgtcaat tcgctttttc atctctctta gttctttcac gtaatgggtg taaatatcta
     6421 ataatgtata cgtgatgatc ttttcaaacg agtttaaatg atttccatgc tttgtcagca
     6481 gccgatccac aaattcggtt tttctatcga tacaagtaat caagagatta tcggaaagta
     6541 caaaagatat tggcgttaat tttttttcga tacgattatc tgactgatct agattaatca
     6601 ctaccaaaga aaatggatgc tctagtttcg tctcataaag gcgctccatc cgagaaactt
     6661 cttccggata ttcggttcct acgaaaatat catcaggaag ctcgaattct tcgattgctt
     6721 gctcaatctc ttcgggcttt gcactatcaa gtacgagcca attatatttt ttttcatctg
     6781 tttctattac attcttttct tcatccacaa agtagtatct caatgtatac ctcctttttg
     6841 gactttctcg aaactattag ctgaagaagc agttctttaa tttgatatta taatcgagta
     6901 ctgcgatttc attttctaat gaaaagctgt caagctgttt gttgaagtcc atgttcaatc
     6961 gtttaccgaa ataattttgc tctaatttag atgtatagat gtccaataat ggatgctcga
     7021 ttttagtcgc atattctcca aattccgaaa caaaaggaat gatttgaaaa aagctgcctt
     7081 ttgcaaaagc acctttgtcc cttagaaatg gatcggaatc attgataagc gcgagtgcga
     7141 tttttgtatt ttccccaacc ttttcaatta acgtctctac tgcattttta gacattgtaa
     7201 tttccattcc tactccccct cttcagttgt tgtcttctat tatttaacaa ctacatctgt
     7261 ttttggttga acttttgcat attttggata tttagggaat ttagctacac aacggaaagc
     7321 cgtcatccct gcatattttt cgtaatattt cttcgttggc ccttcaaaat ccttgctcca
     7381 cggtttcaca tgtcctgaaa aatggataat gtaaggattg ttgcgagttt cttcgtattc
     7441 acgttcacct gctgctgttg gatgtttttt tgcttttgcc atgatatagc cttgtgcatt
     7501 ccaacgcgga tgaagtggta accaacggtc atgtaagata gcatttaatg catcttggtc
     7561 atggaatcgt aatttttctg gattatgttc gatgaaatct aatacttttt gcgtaatatt
     7621 ttcatctaac cattttttca cattgatcag catcaaacct gagttgaaat aacgcattga
     7681 tttagctgaa attttcattt tttccagtcg ttgatggaac ccagcgtctt caacagctgc
     7741 tacgattgaa tcaccgaagt caagacgcca taatttagag atatcttgta aagcgatcat
     7801 gtcgcaatcc atatataaga tacgttcaac ttctgtgccg cggaacaatt ccggaatcgc
     7861 aatacgataa taagctgttt ctggaatacg atcgctgatt accacatttg taaagaattc
     7921 tttattgatt ttcaagaatt ccacatctga gttcattcgt gcgtttttca ctgagaagcg
     7981 taaaagctgt ttactttcaa aatcgatatc atcgtcaatc acatagaacc gaacaaattt
     8041 agacgggttg caattatcta atactgagac aaataatgca gctaaatgtg gtacgaattt
     8101 tgtgttacaa cttgcgacta ctgctatttc ttttttattc attgatctcg cctactttcg
     8161 ttagagtact gtgtgctaat ttttttaagt ataaattggt atacggatga tctttcaacg
     8221 tattccaagg tttatcatgt cctgtaaagt gaacgatcga aggtttttca tttccttctt
     8281 tatactgacg ttcatatttt tcatttggtg ctggatgacg ttcaaaaatc agcgaagtct
     8341 gcatgttcca ttttggatga agttgttccc aatcttcata aagtacagca ttcaaagcat
     8401 cttggtcgtg atagatgatt cgatcgccat tttcactgag gtaatggata gttttttctg
     8461 taatttcttt tttattccat tgatcaatgt caatcaccat cactcctgaa ttgaagtaca
     8521 agtcatcgga atcgattcct aatctttcca aagctttcac ttggcctgga tcgataatag
     8581 cgccgattgt ttttccattt aacggctcat catatagttt tacgatatcg tctagtacta
     8641 acacatctga atctaagtaa aggactttct tataatcctc tttagctaat aagtttggta
     8701 aagaaattct taagtaagcg gtagttgtga tatggtcact gactaggaag tcttcgtaga
     8761 tatctttttc cactgtcagg aattggatac ttgcattact tgaatattta tttaccgttt
     8821 cttccaatcc ttctttacta tattctgata gaccatcgtc aatcacataa aattttatgc
     8881 gtcttgtttt attgcaattt tctaatgcag ttgcgatcat cacgctcaag taaggagcat
     8941 aattttcgtc tgaagcagtt accacaggaa ctacgccgta tctcttctcc atcaaaatca
     9001 ctcctttttc taatcttttt ctaacctgtt ctacatctag aatattcctc atttggtttt
     9061 aaagcaaaat atatgctttg ttttcattga atattttaaa atttttttat cacaaaacgc
     9121 atcggtaagc gctaactatt cgtttttcat ggctttttat tcaaaggtat tgaccaaaaa
     9181 ctactatata tagccacctt tttcttaaga atgttttttg aaaaaattca taatgacaaa
     9241 gcaagttagt ttcatttttt taaattctca tttaatctta aggtaacagg aaaatagata
     9301 tgtaaaaaga aagtaggaag ataaaatgaa actagcagcg attgatttag acggtacctt
     9361 gcttgatcga aatggaaaga taccagaaga aaatatccaa gcacttcgga aatttgatga
     9421 aaatggcgga atcgtaaccg tcgctaccgg aaggaacagc atttctgcta aagatatttt
     9481 ttccgaatta ggaatcggtg gctatttgat ttcttccaat ggttcactga ttgctgaaat
     9541 gaaggatgga aaaatggcga aagttctcag acgttcaaaa atagatagcg atacactgag
     9601 aaaagccttc ttctatgctc aagaagcgaa aatatccatc attgctagcc gagaaaccca
     9661 agatgatcag ctgacattcg atgaatcaaa tctagtcaaa gatgaccctt attatgaaca
     9721 tttcaattta cagaaccatt cttttgatca aattttaaat atgttggaag atccttctct
     9781 tagctatctt aaattagcat taacagataa gagtgaagaa aaactacaga agctacaaag
     9841 agatctgcaa gcagatggta tccaatcagt attctctgat ccgcatttct tagaaatcac
     9901 gcctacaggt atcactaaag ctcattcact tgtttttctg gcggattacc ttggaatcga
     9961 atcgagtgac atcatggctt ttggcgatca agaaaacgac attgctatgt tgaattacag
    10021 cgggttgagt attgcgatgg ggaatgcaca gcgacaagta aaagaaattg caaaccaagt
    10081 aacactgacg aatgaagaag ctggtgttgc ttatatttta aaaaacttct attaaaaaga
    10141 ataaaatgac gatatgaatg taggaggaaa gaaaatgtta gttattattg atatgcaaaa
    10201 tcatattctt gatccaaaca gcgaatttta tattccagag tcagatcaat tggcagaacg
    10261 tattgctcaa agattagcta aagcacgcca aaataatgaa tatattctct tcacacggga
    10321 tataccagtt gaactgaagg acaaagaaga agaacgagaa gatttgcaat tgatccctct
    10381 tctttctcca caagaaaatg aacgagtgat taaaaagtat tactttacga ttccacctga
    10441 aactttagct gaaatccagg aaactttatt tgaaagcaaa gaagaacaaa aagagatcga
    10501 agtagtcggg attgaaacaa acttgtgtgt actctctaat ctgataggcc tgcagagtgc
    10561 ttttcctgaa gcagactttt ttgttgatcc aatgttagtc tccagtagaa aacacggaga
    10621 atccgcttta gagctgttga aagatttcaa cgtctctatc gtcgaatcat aaaaatatct
    10681 atcttcattt acgatattta acacacaata aaaaaagcac gcagaactgt tttagtccta
    10741 cgtgcttttt ctatcaaagt agattggctt ttttatgaca cagagtgaaa cggcaggctc
    10801 acgacctctt tcttaaatgg tgttcaatca gctgaccctc ggtattagct taacaaacgg
    10861 caaaatatga ggaactattt ttccgtttgt taagctaata ctcaggtcaa aacgctgatt
    10921 tcacaacctc ttccttaaac ggtattcaaa agcttgcatc tgcagtaata agaacagcca
    10981 agtaaaaaca taagaagctg tttttacttg gctgttctta ttacttgatg cagggcagct
    11041 ttttcacaac ctcttatgta ccttgtagga ctcgaaccta cgaccggacg gttatgagcc
    11101 gtctgctcta acca
//
LOCUS       DAZKCW010000073        10563 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000073 DAZKCW010000000
VERSION     DAZKCW010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.075"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(170..655)
                     /locus_tag="ACG84Z_002331"
     CDS             complement(170..655)
                     /locus_tag="ACG84Z_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFP9163136.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    745..1090
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1135..1776
                     /locus_tag="ACG84Z_002332"
     CDS             1135..1776
                     /locus_tag="ACG84Z_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFP9163137.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            1795..2430
                     /locus_tag="ACG84Z_002333"
     CDS             1795..2430
                     /locus_tag="ACG84Z_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFP9163138.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2448..3263
                     /locus_tag="ACG84Z_002334"
     CDS             2448..3263
                     /locus_tag="ACG84Z_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9163139.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3582..5018
                     /locus_tag="ACG84Z_002335"
     CDS             3582..5018
                     /locus_tag="ACG84Z_002335"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9163140.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5207..7654
                     /locus_tag="ACG84Z_002336"
     CDS             5207..7654
                     /locus_tag="ACG84Z_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFP9163141.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7884..8951
                     /gene="rlmN"
                     /locus_tag="ACG84Z_002337"
     CDS             7884..8951
                     /gene="rlmN"
                     /locus_tag="ACG84Z_002337"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFP9163142.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            8941..9147
                     /locus_tag="ACG84Z_002338"
     CDS             8941..9147
                     /locus_tag="ACG84Z_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163143.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(9144..10247)
                     /locus_tag="ACG84Z_002339"
     CDS             complement(9144..10247)
                     /locus_tag="ACG84Z_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFP9163144.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
BASE COUNT         3487 a         1803 c         2288 g         2985 t
ORIGIN      
        1 tagaatcaat aaatatggat ttggctaact atggaagaat actcgtatta gttttcagcg
       61 ttcatactag ttgttacatt gtttgattgg ccaaaagaat ttctgatata ttttgtgcta
      121 aataaagaaa aagacgcttg aattgggaaa taagaaaact actctatcat tacaaatttt
      181 cataaactgg cagatgttct aagtaaacaa gtatcttttc aaagtcggaa aaatccataa
      241 tcaacgtagt ggtattgata tttggatgaa agcctacggt atcttgacga tcaatagcag
      301 catcgatcac gacttggatt tttttctctt tgtcgtgcat caatgctaat ggagtcactg
      361 tacctgctgg aacgcctagg aggtcaggaa gctgttcttc agaaacaaaa gataagcgct
      421 tttcttttaa ttgttcagct agttgtttta aatcggcgtg cttttcatca ggcaagatga
      481 caagatagat ttgttttcct tttcttgatt tcaataatag attttttact tgcggaccag
      541 gtagggaaaa agggacattt ttgactgacg taatcgcagg atgatcgact ttttgaaaag
      601 agatacccag tttttttagt agttcataag cttcttgttc ggttgcacga ctcatcgcgc
      661 atcaccctcc tttttttatt agtgtatcat aaaaaagagt tgacaaatga aaaataatca
      721 tgtaaattac acgtaaagtt aaaacaaatg acatcgaaaa gaagagtagc cgttaggtgt
      781 ttttagagag tctctggttg gtggaaagag gcagcagtta accgtgaaac acatcttgga
      841 gtcgattttc tgaagcgtat agtaggaaaa tccggggagc ccgttacagc tgcggtcgtt
      901 gctagatgac cagataaggc tggcttttcc gtgaggagtc ggtaaaaaaa ggtggaacca
      961 cgtgattaac gtcctttgat cttcggatca aaggactttt tgttttcatc tgaacggcaa
     1021 cgactgtgtg aggttttttc tgcaaggaaa aaataaacag aggtggaacc acgtataata
     1081 cgtcctcttg gcatttgcca agaggatttt tttattttaa aggaggaaaa gaagatggag
     1141 tatttgattg aagttatgcc gcaattatta gtaggagcac tcacaacatt gaaattattt
     1201 ttatttacct tgattggctc attaccatta gggattgttt tagcattagg attgtctttg
     1261 cattttaagc cgctacgcta cttgcttcaa acatatgtat gggttatgcg gggaacaccg
     1321 ctgttgttgc aactgatttt tattttttat gggttgccga cgattgggat cgtttttgat
     1381 cgtttcgaag cagcactcat tgcctttatc ttaaactatg cagcttattt tgcagagatc
     1441 tttcgtggag ggatacaatc gattcctcaa ggtcaatatg aagcagcgca agttttgcaa
     1501 ttaagtccct ttcaaacggt gacgaaaatc gtcatcccac aagtgacaaa gattgtttta
     1561 ccttctgtag ggaatgaagt tatcaacttg gtcaaagatt cttccttgat ctatatatta
     1621 ggtttaggtg acgtaatgcg tgctgggaaa atcgcgatgg aacgcgacgc gactttactg
     1681 cctttgctag gcgtggcaat catctatctt acattgactg gtattctaac aatcataatg
     1741 aaacaagttg aaggaaaatt aaattattac cgctaactga taggaggaag aaatatgatt
     1801 gaattgaaga aagtgaacaa agcatttggt gaaaaaaaaa taatcaaaga tttgaatcta
     1861 atcattccag atgggaaaac attagctatc gtaggtcctt ccggtggcgg taaaaccacg
     1921 cttttacgta tcttggctgg cttagaaagt tctgacagcg gagaatttta tttagacggt
     1981 gtaccgttca acccattcga gcttaaaatg aaagaacaag ttgtaggagt cgtattccaa
     2041 gacttccagc tatttccaca tctgaatatt tttgaaaaca ttaccttagc accaaaaatg
     2101 gtattgaaac agacaaaaga agaatacacc aaaaaagcag aagaattagc ggcttcatta
     2161 gggattagtg atttattgaa tatctatcct tatcagcttt ctggcggaca aaaacagcgg
     2221 gtagcgattg ccagagcatt ggctatgaat ccacgggtat tggcttatga tgaaccaaca
     2281 agtgctttag atcctgaatt acgccagcaa gtcgagcgtt tgatcctatc attgaaagaa
     2341 gatggggtaa cccaaattat tgtcacccat gatttagtat ttgcagaaaa tgtcggtgat
     2401 caattactaa aagtttcccc aattcattaa gaaaggagaa gatagagatg aaaaaaacca
     2461 gttttctatt cgctttgatc gcaggtcttc ttctttttgc aggctgttcg aacaaaaaaa
     2521 cttcagcaga taattgggcg actatcaacg aagagaaaaa aatcgttata ggtttagacg
     2581 atacatttgt tcctatggga tttagagata aagacgggaa gctcacagga tttgatattg
     2641 atttagccaa agcagtcttt gaacaatatg ggattacggt agactttcag cccattgact
     2701 ggtcaatgaa ggaatttgaa ctgaacaatg gaacgatcga tttgatatgg aacggctatt
     2761 ccaaaacgcc ggcaagagaa aagaaagtgc aatttacaaa accttatatg gaaaacgatc
     2821 aagtgctgat cacacctaaa gaatcaggaa tcacaaactt tggacaaatg aataataaga
     2881 gattaggtgc gcaaaatggg tcatctggtt atgatgtatt tacgaaacaa ccagaagtat
     2941 taaaagagat agtcaaaaac caagatgctg ttttgtatga tagttttaat gaagcattga
     3001 tcgatctgaa aagcagacgg gtcgatggtc tgctgatgga taaagtatac gcagactatt
     3061 atttgaaaca aagaaacgaa ctagaagact tcaacataac aaaaggttct tatgagagtg
     3121 aggattttgc agttggtgca cgcaagtcag atagtacatt agtgaaaaaa atcaatgaag
     3181 ccctagatca actagagaaa acaggtgaat tccaaaaaat atccgataaa tggtttggcg
     3241 aagatgttac gccgagaaat taacaaatag gggactgtga caaaagacgt gtcacagtcc
     3301 ctttttccga ataaacagtg ttctcctgcc aactccttgt gactcggagc tgaatggcag
     3361 gctcacaacc tcttggtaaa cggtgttcaa aagccagttt ttcggtatta agccaaattt
     3421 atgcaaaaat gtagaaagcc attttcacaa aatttttctt actactcgaa actaagcgac
     3481 tttttcacaa cctcctttac ataattttat tttgttgtgg aaggggtttc gtgttattct
     3541 aaaagaggaa cgattgaagg ttataggaaa ggaagagatg aatggaacac aaagaactta
     3601 cctcatttcc aaaagatttt ctgtggggct ctgcttctgc agcgtatcaa gtagaaggag
     3661 cttggcaaga agatgggaaa ggagaatcag tctgggatcg atttgtacgg atacctggaa
     3721 agacatttaa aggaacgaac ggtgatttgg cagtagacca ctatcatcgt tataaagaag
     3781 atattgcttt aatgaaagaa caaggtctga aagcttaccg cttctctgta gcttggacac
     3841 ggatttttcc taatggacga ggagaagtca atcaagctgg gctcgctttt tatgagagat
     3901 tgatcgacga attgattgaa aacgatattg aacctatgtt gactttatat cattgggatc
     3961 ttccacaagc attgcaagat gaatataatg gttgggaatc acgtcagatc attgaagatt
     4021 tcactcatta tgcagaaaca ttatttgagg cattccgcgg gaaagtccat tactggatta
     4081 gtttgaatga acaaaatatc ttcacttcat taggttattt gttagcagca catccgccag
     4141 gtgtgacaga cccgaaacga atgtatgaag ttaaccatat tgctaattta gcaaatgcat
     4201 ctgtcatcaa taaatttcac gagttagaaa tgcctggaaa aatcggacca agctttgcgt
     4261 atacgccaaa ttatccaatt gacagtaatc ctgaaaatgt tctggctgct gaaaatgcag
     4321 aagacctgat ggccaattat tggatggatg tctatatgtg gggaaaatat ccgattgctg
     4381 ccatgaggtt cttagaagaa aaaggatggg caccaacgat tgaagctggc gatgcagaat
     4441 tgctagaatc tgctaaacca gattttcttg ggatcaatta ctatcaaacg gcgacgaatg
     4501 cattcaatcc attaaacgga gttggtgctg gaaaaatgaa tacgacagga aaaaaaggtt
     4561 catcagaaga aactggagtt cctggaatgt ataaaaaagt tgagaatcca tttgtcgaac
     4621 gaacaaattg ggactgggag attgacccag aaggattaag gatcggactg cgtcgtatca
     4681 caagccgtta ccgcatgccg gtactgatta cggaaaatgg cttaggagag tatgacaagt
     4741 tgacagaaga taaacaaatc catgacgact atcgaatcaa ttacttacaa agccacgtca
     4801 aagccatcaa agaagcaatt tcggatggag cagaagtcct aggctattgc acctggtctt
     4861 atacagattt gcttagctgg ctgaacggtt atcaaaagcg atatggattt gtatatgttg
     4921 atcaagacga aacacaagaa ggatctttgg aacgatataa gaaagacagt tattactggt
     4981 accaaaaact gattgaagaa aatggagaga acctttagtt cacatactta aaacaagaag
     5041 gtacggctgg atatggccgt gccttttctt gataaaatca tttagaaatt aagaaaaact
     5101 gtaaaataag ctgaaaaatg aaagaaagcg tcagttcttt caaacaaaac tttagttccc
     5161 ttactttttt ttgtataatg aaacttgatg aaatgaggga taataaatgg cacaaaagaa
     5221 acggcctact aaaaaaagga aaaagacgaa aaaaacgaaa aagcaaaaac agcagcagga
     5281 acaaatgctg acgattggtg ttgggtttgc cttgatttta tttgctgtct tcggcttttt
     5341 aaaattaggt tttttaggaa tattgattgc aaacggcttt cggatcattg caggaaatac
     5401 ttaccaaatc ctctgtcttt tattagccgt attaggattt tggattgtca ttaagaatac
     5461 agagttttca attggtaaaa accgacgctg gtttggcggc atactctttt atttcggtat
     5521 cttattattg ttacatgccc atttatttgg caaactccat actggggaac caaatatcat
     5581 ggggacgaca tgggatttgt tagccagtga tataaaacaa agtcaagtag acaataacgt
     5641 tggtggtggg atgattggag caatccttta tcattttact tacttcttga ttgcacagcc
     5701 tggaagttat ttagcagcag tgctattact ggcaggagga gcattcctgt tcagtaatct
     5761 ggaaggctat cagctgttaa atggtatcca atcaattgga gaacgagtac aggaattatt
     5821 ggaaggtgat cctgccaagc aagctcgaaa gcaagcggca aaggaagaga gaatgaaaca
     5881 gcgcgcagaa gcgaaagaag caaggcgctt agctgcaaaa gaagctgcag aaaaagaagc
     5941 tgcagaatat gagaagaaaa aagcggtgag ccagcaaagg gaaaatactg ctgatgaatg
     6001 gcaggaacca gaaaatacag agccggagca gctaagtttt gttccaatcg acagttttca
     6061 agaaaatatc catcctgcga atctagagaa accagtacca gatacaccaa aacagaccaa
     6121 tacagcagaa ggtttttcag atgagttgcc agaggatgac ggtacctcat tagaatttga
     6181 gattgaagca gaacaggaaa atcaagacta tgaattaccg acagttgatt tgcttgattc
     6241 tataccaact gtggatcaaa gtgatgagta taaaaaaatt gaaaaaaata tcggcgtatt
     6301 agaacaaact ttccaaagtt tcggtgtcga tgccaaggtc gtcaaagcca gcttaggacc
     6361 atccgtcaca aaattcgaag tccagccggc tgtaggggta aaagtaagta aaattgtgaa
     6421 cttaacagat gatatcgcgc ttgctttagc ggcgaaagat gtccggatgg aagcaccgat
     6481 tccaggtaaa tcactgattg gtattgaagt accaaatgga aagatcagta tggtttcctt
     6541 tagagaaatc atcgaagcac aaccaaacca cccagataaa ttactagaag tacctttagg
     6601 acgtgatgtt tctggacggg tacaaacggc tgatctttcg aagatgcctc acttactcgt
     6661 ggctggttcg actggtagtg ggaagtcagt agcaattaat gggattatca caagtatatt
     6721 aatgcgtgct aagccccatg aagtaaaact gatgatgatc gatccgaaaa tggttgaatt
     6781 gaatatgtac aacggcatac ctcatctgtt gacgccggtc gtgacgaacc ctagaaaagc
     6841 agcgcaagcc ttacaaaaag tagtacaaga aatggaagaa cgatatgaaa aattcgcggc
     6901 aaccggagta agaaatattt ctggttacaa tgaatttgtt caacagaaaa acttggaaaa
     6961 cggaacgaaa catccaacct taccattcat cgtagtgatc gtagatgaat tagctgattt
     7021 gatgatggta gccagcaatg aagttgaaga tgcgattatt cgtttagcgc aaatggctcg
     7081 ggcagcgggg attcatatga tcctagctac tcaacgtcca agtgtggatg ttatcacagg
     7141 aatcatcaaa gcaaatgtac cttccagaat ggcatttgcg gtatcaagcg gtacagattc
     7201 tcggacgatc attgattcta atggggcaga aaagctctta gggcgaggag atatgctatt
     7261 cttgccaatg ggtgagaata aaccgatccg tgtgcaagga gcattcattt ctgaccacga
     7321 agtagaacgg gtcgttcaat ttgttacaga tcagcaagaa gctcattatg aagagaaaat
     7381 gatgccgaca gatgaagttg aaacgacagg tgctccagaa cagccacaag atgagctgtt
     7441 tgaagaagca aaagcacttg tcgttgaaat gcaaacggca agtatttccc ttctccaaag
     7501 aagatttcgg atcggttaca accgagcagc acgtttagta gatgaactgg aagctcatgg
     7561 agttgttggc ccgtcagaag gaagcaagcc tcggaaagta ttcattgagc aggaagaaac
     7621 atcagaaacg ttgccggacg ataatgacat gtaaaacttg tgtgatgaag ggttgaaaaa
     7681 cgaataacca ataaaaagac aaggcatgat gataccaaaa gaaaaaatgg tttttttcca
     7741 tcttttctaa tacggtatga tgtcttgtct ttttagtttt tgtgagatta aagttctatt
     7801 cgatttattt gtgaagtatt gcattaagga aatgaatcat gtatagtatg tagcgaaact
     7861 ttgagaaaaa gagggaaaat actttggaaa aacagtccat ttatggcttg acgaatgaag
     7921 aattaatcaa ttggtttata gaaaacggcg agaaaaaatt ccgagctgcc caagtttggg
     7981 aatggttgta tcaaaaacgt gtaagtaatt tcacagaaat gacgaatcta tcgaaacaat
     8041 tgatcgaaaa attatcggag cattttatca tcaatcctct aaaacagatg gtcgtccaag
     8101 aagcttcgga tggtacagta aaatatttgt ttgaactccc tgataaaaac atgattgaga
     8161 ctgtactgat gagacaagaa tatggcttgt cagtttgtgt gacgacacaa gtaggatgta
     8221 atatcggctg tacgttttgt gcaagcgggc tgctcaaaaa gaaccgtgat ctgactgctg
     8281 gagaaattgt tgcacagatc atgatggtcc aacattattt tgatgagcgc aatcttggcg
     8341 aacgcgtttc acatgtcgtt gtaatgggga tcggtgagcc atttgataat tacgacaatg
     8401 taatggactt tttgcatatc atcaatgatg ccaaaggatt ggcaattggt gctcggcaca
     8461 ttacagtttc cactagtgga ttagcacaca aaatcaagga attcgctaat aacggcttgc
     8521 aagtcaatct ggctatttcc ttgcacgcgc cgaataatga ggtgcgaaca tcgatcatgc
     8581 ggatcaaccg aagtttccca attgagaaat tgatggaagc tgtggatgag tatttagaga
     8641 aaacaaaccg tcgaatcacg tttgaatata tcatgttgaa tcaagtaaat gatagaccag
     8701 agcatgcgca acaattagca gatctattaa aagataagaa aaaattagca tatgtcaact
     8761 tgattccata taatccagtc agtgaacatg atcaatattc tcgcagtcca aaagctgatg
     8821 tattgagatt ttatgatgta ttgaagaaaa acggcgtaaa ctgtgtgata cgtaaagaac
     8881 atggtacaga tattgatgca gcttgcggac aattgcgaag caagcaaatg aaaaaaacag
     8941 ttgccaaata atcgtatcct actcgttttt tcaattacca taaaaggagc agttttctta
     9001 attaaggaac tgttcaactt aaataagaga aaagattcta tagcgaaagc tataaagctt
     9061 tttttgacaa gaaaaaccct catcaagcaa agaaatgtcc tcaatttgat gacagcctgc
     9121 ttgatggggg ttttagcaat tatttaactg attttcttat atccttgctg gctttcttgt
     9181 gtagcatgat aagtttctac gtcaagaatg gcctgtttaa atttttctcg ggtgatttca
     9241 taaggcacat gtttaatatc atttgttgcc atggctttat ctaagattgc ttctaaatcg
     9301 gtcgtgacat tgagattcat gtcggttaac gatactggaa gttggttctt tttcataaac
     9361 acatagattt tatcaaacaa atcgaactgc tgatccatca tcaataaggt cagtacacca
     9421 taactgacag atgctccgtg aaggtatccc tccatttttt ctagaacagt cgtaccgtaa
     9481 tagaatgagt gtgccatagc agaattatag ttattgttaa ctaaaacaga aaccaatccg
     9541 gtagtaacaa tgatatccga aacgacttgt tcaattgcat atgagggacg atcgtcggca
     9601 ctatctttca atgcttgcgt accataagtc aagagacgat caatgcacat ttttccgatt
     9661 tggattccta atctatccgt gtagcctaga tcatcgccac gagcagaaaa agtagattcg
     9721 acttctttgg ataaagcatc gccaatacct gcccataagt atttatcagg tgcttcggca
     9781 ataattgctg tatcaatgaa ggtgtgtaca ggtggttttg aaggaaagaa gagtccgtcc
     9841 attacgcctt cttcgttata gatgacacat accgcagtga cgggcgaaca gttcgaacca
     9901 atagtgggaa aggtgaagac tggtttagct agtttttcac caatgacttt tacagtatcg
     9961 caagcacggc caccaccgac tgcaaacagg acgtctgctt tttggacact ttcatgctgg
    10021 atcaactgtt caatatttcc ataagttgaa ttacccccgt accagagact ggcgacaacc
    10081 tctatttcct gtgtcaaagc tacttttatt ttgttttctg cctttgaaag tgcagtcttc
    10141 cctccaatca gcactacttt tgtcccatat tctttgacga ttccatttgc tttttcatac
    10201 gcatctgttc caatggtata atttggtaag aaaacacttt gactcatatt catttccttc
    10261 tttcttcgtt gaaacgggtt aaaattttaa agagtgatcg atctgactgc ggctgtagat
    10321 ggagtagagg tgaacctaag acaggataag tgatgaataa ggtggcatga acaccttgaa
    10381 atcatcaata agtatcctaa aaacgaacaa gtacaaaaac attgaaaacg acaataatga
    10441 atttttgttc ctcttagtat ttctaccgat tccctttgct tttttgtaat tatctaaaaa
    10501 ttctaaaaat taagattatt atatgaaaac aggttttatt tgtcaattca taattggttt
    10561 ttt
//
LOCUS       DAZKCW010000074        10268 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000074 DAZKCW010000000
VERSION     DAZKCW010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10268
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.077"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(559..1599)
                     /locus_tag="ACG84Z_002340"
     CDS             complement(559..1599)
                     /locus_tag="ACG84Z_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFP9163145.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1948..2274)
                     /locus_tag="ACG84Z_002341"
     CDS             complement(1948..2274)
                     /locus_tag="ACG84Z_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163146.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2261..3049)
                     /locus_tag="ACG84Z_002342"
     CDS             complement(2261..3049)
                     /locus_tag="ACG84Z_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFP9163147.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3417..3707)
                     /locus_tag="ACG84Z_002343"
     CDS             complement(3417..3707)
                     /locus_tag="ACG84Z_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFP9163148.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3843..4022)
                     /locus_tag="ACG84Z_002344"
     CDS             complement(3843..4022)
                     /locus_tag="ACG84Z_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163149.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4019..4369)
                     /locus_tag="ACG84Z_002345"
     CDS             complement(4019..4369)
                     /locus_tag="ACG84Z_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163150.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4362..5687)
                     /locus_tag="ACG84Z_002346"
     CDS             complement(4362..5687)
                     /locus_tag="ACG84Z_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFP9163151.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6137..6751
                     /locus_tag="ACG84Z_002347"
     CDS             6137..6751
                     /locus_tag="ACG84Z_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9163152.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6916..7920)
                     /locus_tag="ACG84Z_002348"
     CDS             complement(6916..7920)
                     /locus_tag="ACG84Z_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163153.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLE
                     LKTLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITA
                     CEIGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEK
                     RNKLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNK
                     SQITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD
                     "
     gene            complement(8379..8636)
                     /locus_tag="ACG84Z_002349"
     CDS             complement(8379..8636)
                     /locus_tag="ACG84Z_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFP9163154.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(8629..8898)
                     /locus_tag="ACG84Z_002350"
     CDS             complement(8629..8898)
                     /locus_tag="ACG84Z_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFP9163155.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(9029..9208)
                     /locus_tag="ACG84Z_002351"
     CDS             complement(9029..9208)
                     /locus_tag="ACG84Z_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163156.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            9306..9542
                     /locus_tag="ACG84Z_002352"
     CDS             9306..9542
                     /locus_tag="ACG84Z_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163157.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISF
                     FLLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
     gene            complement(9589..>10268)
                     /locus_tag="ACG84Z_002353"
     CDS             complement(9589..>10268)
                     /locus_tag="ACG84Z_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163158.1"
                     /translation="EDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFIQRVEEQLYLE
                     SETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEKYIMNVYLERSELVENFVSYT
                     ICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDDYYLVFTRFLTCGTESIVLMG
                     MDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRKRMPYQR
                     FERKKRQ"
BASE COUNT         3132 a         1876 c         1472 g         3788 t
ORIGIN      
        1 cgttgcgggt aataccgtaa cactgaaggg cacgcattaa ggcgtcatct taatgctttc
       61 ctgtaggaca ctgacggaga ttaccagtct cccgagcctt acaggggcct ttcttttttt
      121 tgtattttca attatcacaa tttatcgtcc aaaagtgcag aacgaaaatc aattcatcac
      181 aagcatatca gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt gtaattgaat
      241 attagcagca ctgcctgaaa agaagtaata tcaggctttt cagcttgggg aaataagtga
      301 attacctctc ttcatgaatt attataactc aaaaaagcac atatgcaaac actagttccc
      361 tatttttttg aatgaaaaat aactaaaata tctaacgatt atgactttaa aacctacgtt
      421 tgtgattgtt ttcataaact tttaatctaa aaactccgga ataatagcta tttatttgta
      481 acatttgtaa taaaattaaa atcataaaaa agttctaatt taaaattgat catttttata
      541 gtgatcgctt tttatcaact actctagcca attttccgta ctaactgttg gtaattcgtt
      601 aaatgtttct ctttgttcgt ttgcaagctt tgccgcaata gctttttcga caaaccaatt
      661 ttttacataa acgaaaatta gattctgcaa attgtttact ttttcagttt tttgtttttg
      721 ataagctttc agcaaagtca tatataatcc tttgtcagca tcaattccat aagattccag
      781 ttcttcataa acaacaactg tttgctctaa ttcttcagct tttttctttg cattatgaat
      841 agtttggacg gttttttgag cgtcttcgta agtactagaa aatgttttta tcaagtttaa
      901 tacattttct ggtacaaatg tatttatact gtcctctttc atgatgtcga cgaagttatc
      961 tagtaaaact tgattttgta actgatcagt ttcagtgtct attatgtgtc tattagtgtc
     1021 tatagaatta gaatagaata gattgtctgc gattttcgca attacggttg agtccttgat
     1081 atgactggat tttgccgtat ttgcgatttt cgcaattacg gtggtatcat tgatttctcg
     1141 cggttttgcc gtatttgcga ttttcgcaat tacggtggta tcagtattgt cttcctcttc
     1201 catgatttta aagacgtctt gattcgttac ttctggcttg cctaagtaca ataaattagg
     1261 catggattca atcttaccgt cacgtttatt tactcttcct ctcttctgtt tcagaagacc
     1321 tgctttttct aattcctttt tgattttaga tactttacct tcgcggcatt gtaacaattt
     1381 cattaattct tcaactgtga atatgaaaaa tatattatca tcagaatcta cccagttatt
     1441 tttgactgaa taatcaaatc gatctttaag tagcatataa gcaatttttg catcatttga
     1501 tagatccatg tatttttcgt tagtaaaaaa taccttaggc atttgataat atttttcacg
     1561 ataaatttct tttgatttgt aataattaaa atcattcata gccaatcctc tttctgtagg
     1621 atagcgtttt gttcaaaact atgttacaat gaattaaaca aatatatcta tccactatat
     1681 atttttctac tgctgataag tcgccaaact ttgttaaagc agtagtcttt ttttatcttt
     1741 ttttagttta ccttaaaaaa taaattaaag caaaccgctc tatttcaagg tttaagctca
     1801 tagtaactat atcacgatat tacaataata ttatatcacg atatcgtaat attacaatat
     1861 gaagataagc gacttatcag ctttgatact actgattttt ataaaaaaaa tatcacgata
     1921 ttatgatatc gtgatattga atgtaaatta aattttattt tgtttctttg ctagtttata
     1981 tccttcaatc aagtattctt caggtatgga ctttaatagc gcatcttcta taacgtctgg
     2041 tttacttttg tctgattcag caatagtcgt ccaatatttg agtgctgaca ttagaattgg
     2101 atttatacga atgctatctg ctgttcttac actacttcct tgatctttta tgactttact
     2161 tatatttttc ttggttaatt cgatttcttc tacttctttt gatttaaaat tctttttatt
     2221 tttatttcct agtaatctac ttactgcagc ttgactgcga ttatcttctg ccatcaaaat
     2281 caccaacttc ttttaaatat tcttctgtaa atgctttata gtcatcttca gctgttgagg
     2341 gtttattaaa attgattaga tctgatccag cagcttgcgc ttcgtcaacg gttattgtcc
     2401 tacgaatata agttttgaaa atttttgcac caatgactct agaaatttcg gttgctgcag
     2461 acgtcatttc tttagaaatg ttataacgct tattatactt agtaaataga actcctcgta
     2521 cttcaagctt gtcgttcgta tattctttta ccgtttcaat agtttcactt aactttatta
     2581 gtccttttaa tgagaaatac gcagcttcaa ctggaatgat aatttcatca gaaacagtaa
     2641 atgcgttgac tgtaagcatt cctaaacttg gtggacaatc aattataata taatcatagt
     2701 tgtccttgat tggttgaagt actcttttaa gcctgtgttc acttcctact tgagtaaatt
     2761 ccctctctgc agaagaaagg gctatgtcgg ctggcaaaac atcaattcct ttatagtcca
     2821 gaatagcatc tgtaatgtca gcctcccctt ttaatacttc ataaattgta ggttggtttg
     2881 ttccatctat atcgaaacct acattatctg tagcatttcc ctgaggatca atgtccacta
     2941 aaagtacatt tttaccgtaa acaaatttca aacatgctgc taaattaacg ctagtcgtag
     3001 ttttagaaac tccacctttt tgattggcta ctgacaatat tcttgccatt aaaatatccc
     3061 ccattcatct tatattataa tataattata tcataatatt gtgatattgc aatatcgtat
     3121 atgcattata ttgtaatatt gtgtgattat tttgttttaa agatatatat cggttcggat
     3181 ataaagatta ttcatatgtt attcgaaatt aaaataatca ctttttatta ctttaaaatt
     3241 ttttattaat gataagaaat atgttttgcg agcagcaact agaataattt aaacattact
     3301 aaactgtcta tattgttact aataattccc ttcttatagt gcattttctt agaaaaaaac
     3361 aatattacga tatcatgata ttaagatatc gtaatattat acaattgtga ttgatattat
     3421 atatgttttt ttattttttt atcatgttta atcttgaagg aatcatattc tttttctaaa
     3481 gacaggagct tttcataaac atcagacatg tttaaactag aggccaggct taaatcataa
     3541 acgaatgaag caggtaatga ttttattcta cgttgtcggg ttatccagct tgcaaccgtt
     3601 ccttgtgggt aggcatataa ctcacaaaat tgttctacag tgattcctaa attcttgata
     3661 atgtaaacat tgatcgggtg cgagtaaaca aatgtattga tagacatggt gcgtaagcct
     3721 actttctttt attattgcgt ttgcaataat agtttaacac acgcattatt ctagtatcta
     3781 ctcctatttg taaaaacaaa aaaggattca tagagataac tctatagaat ccgtaaaata
     3841 ccttatatat ataacgggaa gatataaaac ctaaaattat gataacctgc tgcagcttct
     3901 acatagaaag agaagcgctc aacaccaacc tcatttatca aacgttggcc ataaccccaa
     3961 atctcttctg atagctgatc aaaggttata tactttagct catattgctg gataatgttc
     4021 attctaatcg actccattta ttatcctggt aaaattcgat atgacgtatt tcgtcgtagt
     4081 gaattttgtc ttttccaacg tagatcccca gctcatcact acctaagatc ttgccaatga
     4141 tatcttctgg atagtatcct tcagcgtttc gttcttcttt ttgaatagat actgatctat
     4201 tttttatgac tgcagcgttc aatacttccg caatctcttc agtcgtcatt tgttcttttg
     4261 ctaaattttg actggttcgt tgttcattgt cggcatcaat ttcttcagta tgatcagata
     4321 aataaaaccc tgcccacttt aaacgtccac gatcattgta atcaatcatt tttaattccc
     4381 ccatttccgc ccgcatgacc accaacaagt gtgcttctag taatgcttct agcgccttct
     4441 aacattgaag aagcatgtac aatcgacgta aaaccatatt tttgccgaat cttgtcaata
     4501 attttatcta aattttcttc gtcaatttgc ttttgtggat cactaaataa atccagctga
     4561 agcgaatcgg tgtacacaag cttgctatag gttattccaa catgccttac ttcttgtcct
     4621 tcataatact tatcaaacaa gaaaagacaa taattctgca attcctttgt attatctgtg
     4681 atagggatct tcatctggtg tgaaaaccct ggtctcgttt ctaagatcga cgtgccaatg
     4741 tgtaaatgga cacaacctgt tttacagtta tgctgcctaa tgcgtatcgc tacttgttcc
     4801 gccatttctt ttaccaccag ctcgatttca tttcttctag tataatctcg tggtaacact
     4861 tgtgaatttc catatgattt ttcctttgtc ggttctggtg ggattgctat atctgttcga
     4921 tcgatcccat tagcatggaa gtacagctgt aagccaatca cacctagtct attcttaatc
     4981 gtataaggat tccagttagc aagatctcta atgctcataa tccccatctg attgagtctt
     5041 tttttcattc gagagccaat tccccaaaag tccgtcattt caggaatatt ccatactttt
     5101 tcaggaacgt tttcgtacgt ccattccgca acaaatcctt cattatgctt tgcttcgttg
     5161 tctaaggcta gtttagccaa aaggggatta tctccgacac ctactgtagc aatcaatcct
     5221 agctcttctt taatattctc ctggatcatt tgagccagct tctttctccg ttgacttcgt
     5281 gttccttcag tcgtaaaaag attcagtgat cgggtcactt ttaagattga ttcatcgatc
     5341 gagtaaatca gtagatcttc atcagccaca tatcttctga aaatattatt tacctgcata
     5401 tttcgcttga tatataggtt catacgtggt ggaacaacgt gtagtgtttt aggaaatggt
     5461 tgtggtaagt cacgtggtct actcacattt gtaataccat accgcttttt tgcttcagga
     5521 gaagaagcta atatcaatcc tgaaccagta ttatcagctc gactcataac aacaagttct
     5581 gttgttaatg gatctaaatt tctttctata cattcgacac ttgcgtaaaa gcttttcata
     5641 tcgattaaaa agtaatcatt tactggctct tttgaataat ccatcataaa taacactcca
     5701 ttctttcaca ttatacaaac atatgttcga tattgtaaag aagaaatagc taaatacata
     5761 aaaaaagaag cataggtatg ctatcaccct gcttcttctt ttgatttgta tgatcaattt
     5821 attctatcac tttactaatt aatttgaaaa tctaataaaa actctcactc taaaagagtg
     5881 agagactgca aattagagta cggacttttt tggagttccg ttctttaata ttaacaaatg
     5941 aataaaatcc ttacaacatt tgagaataag ttatcagtag acacttacaa aaaattctca
     6001 tactatttcc tccatcatta gtttttgtct atataaggtt taccctaaat agacactggt
     6061 ataacattga aaaatatggc ttcctcgtgt atgattaggg tgtattttaa atagttgcag
     6121 aaagtaggta aaagttttga gagttgcata catacgtgtc tcatcgatcg atcaaaatga
     6181 acaacgccag attgaagaaa tgaaaaaatt cggtgcagag agaattttca tcgagaaaca
     6241 atctggcgca acgattactc atcgacctgt tttccaagaa gcattagatt acgtccgaga
     6301 tcaagatatt tttattgtgg aagctattga tcgacttgga agaaattatg acgagatcat
     6361 cgcttcagtc aattacttga agaagaaaaa tgtgaagctg atcattacta gtttaccgat
     6421 catggctgaa gcaattggca atcctctcct ggataaattc attaaggatc tgatcatcca
     6481 aattttggcc atgatcgctg aacaagaacg gactgaatcg aaacgtcgcc aggcacaagg
     6541 aattaagatc gcaaaagcaa acggcgtcta caaagggcgg cccaaattat acagtgcaga
     6601 cgcaaaagat ccccaacgtc gccttgttta caaaagcatc gttgaagatc ttaaaaatgg
     6661 tgttgcgatt gctaagattg ctaaagacta caatgttacg agacaaaccg tgtatagaat
     6721 aaaaaaagac agcatggtca atgacaaata gttgatcatg ctgcttttat tatcttctca
     6781 tctttaattt cctacatata attactatct ataaaattaa gtcttactca gaacagataa
     6841 agcataaaat tccaacaaac cattttttac ttaactaaat aaagagtctg ttaatataat
     6901 cttcacttat ttacgttaat cccctactgt atttgttggt tccttatcta tattttctac
     6961 aaaatcctta ttatcttgtg atttagcttc gtataattct ttgtatgtcg acacattggt
     7021 tatactaatt cctatagcta gttcttgaga ctctactttt ctctctagct cctttgacaa
     7081 agtgatttga gatttatttg gttccgttgg agtcaattct atagattctt cataaaaatc
     7141 tctatacata aagctatcat taattttata aaaaaaatta aatgttttta gcactgccat
     7201 ataacattca aaacattctt ctatagttgg tttacttcct tgaggagaat gaaccaattt
     7261 attacgtttt tctatgaaat ttttaatttc ctttcttatt tctttcggaa actcaatatt
     7321 aaagtaccct ttaaacatgc tccctaataa tttgtctaca gggggagatt gtaaattctc
     7381 aaatattaga gttaaatcag gtttctcttg ttgataaaat tcctttaccc ctatttcaca
     7441 ggctgtaatt atcgaaataa acctatctct agtatttgat atatttttac ttcttttaag
     7501 gagtataaga gaaaagggga tactttcgtg tccatgcatg taattaacta attgttgagc
     7561 ttcagaagtt atatctctaa ttatatagtt aacggaatta ggaagtgtct ttaactctaa
     7621 tgaaatttct atccaattac tatcttctaa tctgtatatg ctcgaagtat aatttgattc
     7681 gtcagcaagc atcgctacat cccaaacact gatcataaaa tcttttaaac gttcaatcat
     7741 ttcagcaata ttgctaaaat cagctaattt ttctttagaa taaaaaaaaa catttatatc
     7801 agaatcaata aattctattt tttttattac tatatcgtca tcattatctt gaccatttat
     7861 gtttattgtt ccctgagtgg ggagtacttc tttcaaattc aagttaaatt tatattccat
     7921 tacttctcct ccaatatata aaaattactt aactgtatcc aaatttaata tgtaaataaa
     7981 tcattaattt ttagctaaat tctatgagaa gtttattttt gttgtttttg ctaattaact
     8041 aaaactagta caaaaaattt aaaatagatt attaaaccta ttgcttattc tattcagtca
     8101 tatatataag cgtcatcctt tagtaactaa catcccacac tacaatagta ttataacata
     8161 tctattcaac ttcaaattgt tgaaatttaa gccatttata tttacttttc ctcaacttta
     8221 gaaatgattt tactaacctt atatccgtaa tacgcgtaac aaacacattc attaataaca
     8281 atcaacacta agctatatta gctttttaaa tgactagggt aaataaaata aggatcaaaa
     8341 acttttaagt ttctgaccct ttccttactt ccgattggtt aatagtgatc ttttgcagaa
     8401 taaataaata tcgtttcatt ttcaactcta tatatcagtc tatgttcatc tgtaattctt
     8461 ctggaccatt ttccagataa atcatgcttt aatggctcag gttttcctaa tccagcaaag
     8521 ggggaacgat cgatatcttt tattaacttg ttaatctttt ttatattgct tttgtttcct
     8581 tgctcatgcc aataaagata atcatcccaa gcatcatcag accaagcctt aatcatcaga
     8641 ttcaacctcg attaagtcat gtgttttaaa tgcacctttg gagaattgtt catctcctcg
     8701 acgaattttt tccatgacgt aattattaga aagtgttctc aacgtttctt gcatagaatc
     8761 ataatctctt tttgataata caacaactgt atcttctaca tctttacttg ttacaataag
     8821 tgtttcagca tcctcattaa cttgtttcat ataactacgt aaattttggc ggaaatttga
     8881 ataagctact gcttccattc ctttcacccc ttatttattt ctataaaaca attgtacatt
     8941 atattgtaca attaagcaaa tgattaatat tctaacttct tataattaaa agtgctatca
     9001 cttttagttt ttaggataaa aagtgacgtc actttttgag tgctggtacc tcaaatcctg
     9061 ctttttcttg ggcaatcaat aaatctaacg caatacacat aatcctggat tcacttttgc
     9121 cgtacttctg ctttagttgc tgcaattctt tttgtctctt ttcatccaac gtaacgggta
     9181 accgtttatt tcctattgca attggcatta gtactctctc ctttcatcga aataacccta
     9241 tgaaaaatat ggctgcaatc atcttgaata gtagactcac aagggctaat acaaagcgcc
     9301 aaaagatcaa acaaaatacc agtattgcca aaaatactac gaagtttaaa tgcacagctg
     9361 cagcatggcg cataagtatt tcgccaacaa ataggactaa caatagagga atgattttat
     9421 tcatatggat ctccttcttt ctcttaggtt atcgggtgtt gcccgcttat ttcgcaccac
     9481 ctaagcggcg ggggcggttg gagcgattgg tgcgaaataa gaaccattcc cttagttact
     9541 aggttttttg tccttatttc acacattctc acttttcggt ataaatgatt attgcctttt
     9601 tttcctttca aatcgttgat atggcattcg tttacggtca agttcatttt ggatttcttc
     9661 tgtatcgtcg taagtatagg tgtctaaaaa atcagttaaa gtcgtgtacc agtcgtcgcc
     9721 tgggttatct acttcttcta catattccct caaaaatgct tcgggtacag cgagttcata
     9781 atccattccc attaacacga tagattccgt tccacacgtc aaaaatctag taaatacaag
     9841 gtaataatcg tctatcgtcg catctttgct gtttagctct tccatttctt cttccattaa
     9901 ttccatgctc tcaaaaattg aataatattc tgattctgag taatagtgtt tcctgcaaat
     9961 cgtgtagctg acaaagtttt cgaccagctc actcctttct aggtaaacat tcatgatgta
    10021 tttttctgtt tctagtcgta gaagctccgt tccttttttt accgtttcag gacgacgttt
    10081 atacacgtct aaacgattat ggctgactgt gaccttcgtt tgactcgttt cactttccaa
    10141 atacaattgt tcttcgactc tttgaataaa gtacttcatt tcttccatac aactaaagtc
    10201 tttttgaatc cgtctgatta cttcattcaa atgttctttg tttgttaaaa agtgtgacac
    10261 atcttccg
//
LOCUS       DAZKCW010000075        10208 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000075 DAZKCW010000000
VERSION     DAZKCW010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10208
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.078"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            351..620
                     /gene="rpsN"
                     /locus_tag="ACG84Z_002354"
     CDS             351..620
                     /gene="rpsN"
                     /locus_tag="ACG84Z_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFP9163159.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            635..814
                     /gene="rpmF"
                     /locus_tag="ACG84Z_002355"
     CDS             635..814
                     /gene="rpmF"
                     /locus_tag="ACG84Z_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFP9163160.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            846..1223
                     /locus_tag="ACG84Z_002356"
     CDS             846..1223
                     /locus_tag="ACG84Z_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163161.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1244..1393
                     /gene="rpmG"
                     /locus_tag="ACG84Z_002357"
     CDS             1244..1393
                     /gene="rpmG"
                     /locus_tag="ACG84Z_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFP9163162.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1417..2400
                     /locus_tag="ACG84Z_002358"
     CDS             1417..2400
                     /locus_tag="ACG84Z_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFP9163163.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2430..2552
                     /locus_tag="ACG84Z_002359"
     CDS             2430..2552
                     /locus_tag="ACG84Z_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFP9163164.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            2570..4093
                     /locus_tag="ACG84Z_002360"
     CDS             2570..4093
                     /locus_tag="ACG84Z_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFP9163165.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            4117..4356
                     /locus_tag="ACG84Z_002361"
     CDS             4117..4356
                     /locus_tag="ACG84Z_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163166.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4549..5010)
                     /locus_tag="ACG84Z_002362"
     CDS             complement(4549..5010)
                     /locus_tag="ACG84Z_002362"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFP9163167.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5205..5423)
                     /locus_tag="ACG84Z_002363"
     CDS             complement(5205..5423)
                     /locus_tag="ACG84Z_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163168.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            5541..7157
                     /locus_tag="ACG84Z_002364"
     CDS             5541..7157
                     /locus_tag="ACG84Z_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFP9163169.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(7398..8738)
                     /locus_tag="ACG84Z_002365"
                     /pseudo
     CDS             complement(7398..8738)
                     /locus_tag="ACG84Z_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9176..9322)
                     /locus_tag="ACG84Z_002366"
     CDS             complement(9176..9322)
                     /locus_tag="ACG84Z_002366"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163170.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            complement(9361..9555)
                     /locus_tag="ACG84Z_002367"
     CDS             complement(9361..9555)
                     /locus_tag="ACG84Z_002367"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFP9163171.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            complement(9465..9797)
                     /locus_tag="ACG84Z_002368"
     CDS             complement(9465..9797)
                     /locus_tag="ACG84Z_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9163172.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
BASE COUNT         3400 a         1616 c         2015 g         3177 t
ORIGIN      
        1 aaaattggcg ataaaccagt taaacataaa agattgaata aaaagttata gtttctttca
       61 tattgccgtt ttaagtagag gaaaagctac ttaaaacggt atttgtgttt gattggacta
      121 ataaaagtga attcttattt ttcagagcct aaactgcata ttcttttaaa tgatttgatt
      181 atctctatgt accgataaat tcgttttcaa atagttatct attcatatga gttttatttc
      241 atgttattta ttgttgacaa gagcaactct tgttggtaaa gtatcagtgt caaaacgtaa
      301 cgattacgat ttgaggtgtc taaatcaaaa taaaaggagt ataaaggtat atggcaaaaa
      361 agtcgaaaat tgctaaagca aagaaacaaa tggcgatgat tgaaaagtat gcagataaac
      421 gtcaggaatt aaaagccgca ggagatcgca ccgctctcgc taaattgcca agagattcaa
      481 atccgaatcg tctgaggctt cgtgatcaga cggatggtcg tccaagaggg tatatgcgaa
      541 agttcggtat gtcccgtatt aagtttagag aacttgccca tcaagggttg attcctggag
      601 taaaaaaagc aagttggtaa aaggaggaaa tatcatggca gtaccagcaa gaaaaacatc
      661 taaggcgaag aaacggttaa gaagaactca tcaaactgta gtaaaaccag aaatttcatt
      721 tgacgaagcg aatggtgatt atagacgtag ccatcatgta tctttaaaag ggtactataa
      781 tggaaagaaa gtaattaaag gagcttcaaa atagtttaat atataacttt taggagggaa
      841 tcaaaatgga aattatttac ccacctttag ttgaagaagg attaaagtat tatcttgaaa
      901 cgacccagca atcgctagat aaatgcactt tttatcgttc gatggtagag agaggaatta
      961 ttactgaaac gggtttaccg acccaacagg caattgaaaa tggattagtc aaagattact
     1021 atgaggacca aggcttatca tttgatgatt ttttaagaat ctatccaatt tttgaagagt
     1081 atgacgagga gttatttcaa tgtatcgatg gttattggga gatacctgtt gatatgaaag
     1141 aaaatttagt ttcacaattg gaatctggcg agttaacttt tgaagatgca caacaaattc
     1201 aagcatatct tgaagatcga taagtattga aggaggaaga tttatgcgtc aaaatattat
     1261 tttggaatgt gtcgaaactg gagaacgtct gtatctcacc agcaaaaata aacggaataa
     1321 ccctgaacgg ttagaattaa aaaagtattc gccaaaattg cgcagacggg caatttttaa
     1381 agaagtgaaa tagctaagtg gtaaaaaggt gacaaaatgg gcataccagt tacaatcgtt
     1441 tctgggtttt taggggctgg aaaaacaacg ctaatcaatc aagccttgca agtctcaccc
     1501 taccccaggg aagaaattat tataattgaa aatgagtttg gtgaagttgg gattgatcac
     1561 aaattattag ttcatagcga ggaacgggtg ttacaactaa ataatggatg tatgtgttgc
     1621 agtcttcgca gtgatttatt agcaatattg atttctttac tggaaacaat agaagaacat
     1681 caacaaccaa tttcacaaat catcattgaa actacaggta tagcagatcc ccaaccaatc
     1741 attcaaacac ttttaacagc gcctcaacta agaggaagag tatatatcga tagtttattg
     1801 actgttattg atagtgacag ttttgaactt attgaaagag aaccacaagc ccttaagcaa
     1861 cttgtcatgg cagatcgcat ttttgtgtct agaaaacaaa acttgaattt atctgcacta
     1921 aaaaaattac agagagaaat caaaagtatt aaccctttat ccgatattcg aatgttcaca
     1981 catagtgaaa cgattcaaaa aaaggatttt tataatttga aaaaatttaa tcatccctta
     2041 gtttttgaaa gtgattcatc agaaaatcac tataatggca aatactatca tcaacaccat
     2101 caagtacatg agtttaaatc aattctctta acttcagatc aagacataaa aaaagatttt
     2161 ttactccaat ggattgactg gctgatttta accaaccaag ggagcctgta tcgttttaaa
     2221 ggattgattg ctttacaaga gcaggatttt atagttgcca tgcaagaggt aaacgaacag
     2281 gttaattttc aatacaccac tcgacaaaaa gaccaaacca ctattattct aatcggaaaa
     2341 atgttggatg aagaaaggat caaacagagt tttgataaat tactggcgga aagcaaataa
     2401 tgataagtag tgattggggg taatttctaa tggagaaaac ggatatatct agtgcatatc
     2461 gacgacttaa aagcccgaat attaaaacta gaaaaagggc attaaaaatt atcaaagaac
     2521 ataaacgaaa taaaatgaag aaattagcat aattaaggaa ggaaaaagaa tgaagaaaat
     2581 cagtgtagga cttattggga tagcagctct aggattattg ggagcttgct ccagcactaa
     2641 tgatgcaaaa gtatcgaatg ataaagatgg aaaattagaa attgtaacaa cattctatcc
     2701 aatgtatgat ttcaccaaaa acatcgtcgg cgatgaagcg aacgtggatt taatggttcc
     2761 agcgggatca gaacctcatg actatgagcc ctcagctaag gatatggcaa aagctcatga
     2821 tgctgatgtt tttgtatatc ataacgaaaa catggaatca tgggtaccaa aagctaaaga
     2881 aagttggaag aaagctgggc ctaatgtagt agaaggaaca aaagacatga ttttattgcc
     2941 aggtagtgaa gaagaagatc atgatcacgg agaagaagat caccatcatg aactagatcc
     3001 tcatacgtgg gtttcaccca aaatggcaat taaggaagtt tcaaatatca aggatcagtt
     3061 agttaaattg tatccgaaaa aagcaaaagt atttgagaca aatgctgaaa agtatttgac
     3121 taaactgaaa cggttggatg ctgactatac cactagtctt aaagaagcga aacaaaaaag
     3181 ttttgtgacg caacacgcag cctttggata tttagctttg gattatggat tgaaacaagt
     3241 tcctattgct ggactaagtc ctgaagaaga gccatcttct ggtcgattag ctgaattaaa
     3301 agagtatgtt aaaaaaaata agatcaatta tatttacttt gaaaagaatg ctaatgataa
     3361 aattgcaaaa actttggcca acgaagctgg gataaaattg gaagtactga atcctcttga
     3421 aagtcttaca aaagaacaaa tggataatgg tgaagattat gtttcagtaa tggaagacaa
     3481 tctaaaagcg ttagaaaaaa caactatggt tgctggtgaa gaggtagttc cagaaaaaga
     3541 agcgaaggat gaaaagacag ttgctaatgg gtactttaaa gatgccgatg tgaaggatcg
     3601 cgaattgagt gattatacag gcgaatggca atctgtttat ccgttgttaa aagatggaat
     3661 tttggatgaa gttttcgatt acaaagcaaa aatcaataaa gacatgacag ctgccgagta
     3721 caaagattat tatactactg gctataagac agatattgat actatcaaca ttaaagacaa
     3781 caccattgat tttgtagtca acggtgaaca tcatcaatac acatacaaat atgttggata
     3841 caaaattttg aattatgaaa aaggaaaccg tggtgttcgt tttaattttg aaactgatga
     3901 tgcaggtgct ggtcgtttta aatatattca atttagtgat catggaattg caccaagtaa
     3961 ggcagagcat ttccatattt tctttggtgg agaaagtcaa gaaaaactct ataatgaatt
     4021 gcataattgg cctactttct atccagcttc attgtctaaa catgaaattg ctcaagaaat
     4081 gatggctcat taaaattcaa tttttggagg aaatacatgg taagaaaagt attattgtct
     4141 atggattcca agaatattga tgcttatcgg cgttatcgat ttgcaaagca aatgagatta
     4201 aatgggagta cattagctga tattgctgca actttacatg ttagtattga cacagttcat
     4261 agagtattaa aacgggatcc tgattgttgt tttatcaagg tcaatactgg aagaagtaga
     4321 cgtttagcaa aacggcataa tagcttggcc aattaattga taataccaga gtagatcatt
     4381 tttcccttat ttggatttga tctgcttttt attatgtctt gaattgtcaa atcaagcgca
     4441 acactttatc aaagaagact tcataaggtg ttctccaatc taaacacttt ctaggtctgt
     4501 tattcagttt ttcaatcatc tgatttatcg ttgagttatc taccgtagct atctctttcg
     4561 attttggcaa gtattctcga atgagtctat tcgtatttta atttgttcat tgttgccaag
     4621 ggcatgagga tctggaaaat aaaagggcat attattcaat gcttctgtaa ctgcgaaatg
     4681 attggagaat tcttttcctc tatctggagt gatcgttttg accgcctcat ttggaatact
     4741 gcttaaaagt tcaatcattt tctcgctcac ataagcggct ttctttctgg ggaccttctt
     4801 tcctgctaaa aggaagcatg attttctgtc tgtcaaagtc actaaacaag taccaccagt
     4861 tttgccagct acaatatcgg ctttccaatg accaaaatca cttctatcat ctgcggattt
     4921 tggacggcca tggatcgaat gagtaaggca aatctttcca cgagactcga catgattttt
     4981 tgtatgtctt gtttttcctc gatggtgcaa tgaacggatc aggcctttat tgccgtgtga
     5041 gaggggttct gtatcgaaaa gatcattgca aattgcacgt tagatcgtga taaaactaat
     5101 tgaaaagtcc atatgttcat gcttcaaacg attcgagatt tcctctggcg accactgaaa
     5161 atcgacaaat aaatgacgaa caattgacca aactcacgga tcatttagaa tgtgataacg
     5221 tccgcatttt tttcttcgat aagcataatt tttttccgct ttggaaggtg aatagttttt
     5281 ttcttgtttc ttctcagttc atgtaaaata gtaaacgggc tatgctgaat gtcgttgcca
     5341 attatactaa tagaaaatcc ttcttcgtga agcagaaaga ttctttctcg ttcgagtata
     5401 gtaagatgac gatactggct cataattatt ttccttctag gagtgttctc gacaaactta
     5461 tactagttgg atatcgatta tgactcattt ttatgtgttg cacttaaagt gtaaattcaa
     5521 ggtatagaaa gaggttccct atgaaaaaaa tacctattac aatcttaact ggctatcttg
     5581 gttcaggaaa aacgatactt ctaaatcata ttctgtacgg tgatcacgga aaggaaattg
     5641 ctgtcattgt aaatgacata ggggaagtaa atgttgatgg ggtattagtc gacaagaaag
     5701 gttttaaaag aactggagaa aaacttgttt cgatgccgaa tggatgcatt tgttgtacat
     5761 tacgcgaaga tttgattgtt gaactagatc aattagtgca attttctgac ttgaatcaaa
     5821 ttgttattga agcttcagga atcagcaaac caattccaat tattcaagca attatattag
     5881 ctaaaaaccc tttagacatt gatttgaccc aacgattaga gattggtgcc attattatag
     5941 tagtggatgt aaaacgtttt tgggataatt tcgaaacggg tgaaaagatt caggaaagaa
     6001 aagctgaagg taatgtagtt gaagaagaac aggatattcg tggcttgtta attgatcaat
     6061 tcgagtgttg taacatatta cttttaaata atagtgactt agtgtcaacc aagacgattt
     6121 acaaaattaa cggtctaatt gctaagttac agtccaatgc caaaataatt aggacaatta
     6181 aaggtgaagt agacttatcg aaaattctaa atacaaatct ttttaatata gatgagactt
     6241 cctattcagt gggctggttc aaagagttag agcttggcta tcaaaatcat attcctgaaa
     6301 cagaagaata tggtatctca agttttatct atcgaaatcg gttactcctt gacgcacaaa
     6361 aatttgccca tcttacggat aaaaattttc ctggcaatat tacaagagca aaagggtttc
     6421 tttggtttgc ccaacatagt gatttttcga cgatctttga aacatcgggt agctataaaa
     6481 gtattgaatc attaaattat tgggtagcta gtttacctaa aattgagtgt caaatgatta
     6541 tacaaaaaaa tcccgaattg aaggaagcct ggcatccgtt gtttggtgaa cgcattaata
     6601 aactagtttt tattggtatg aagatggatc aacaatgtat taaggaacaa cttgagggtt
     6661 gtttaactga ttctcttaat gcagataatt tccgaaaaat ttcaccattt ccatggaaaa
     6721 agtctaatat gtttagccag atatcgttaa tgaaattttt aagaaaagct ggtgtcaaga
     6781 taggcgatgt cataattatt ggcattttga ttattacctc ttttattccc ttatttgtat
     6841 tctctataga aaaggagaat gaaacaactg aagatgctat caaatatgcc atcgttcgaa
     6901 ttgatggcaa ggaaatggat cgcttcgatt tggataagat caatcataaa ctcgtgaatt
     6961 atcatcctgc gaagggacaa tataatattg ttgagattaa agatggaaga attcgagtta
     7021 aagaagataa tagtcctgat caaatcgcgg ttagaactgg atggatctca aaacccggtc
     7081 aaacgagtat ttgtttaccc cataagttag ttattagtat tgagaaaaaa gaaagcacag
     7141 attactacat ttactaatct ggaaatagat gaggaggttt ttaataagaa aaagatatta
     7201 ttattaataa tagcaggggc tttattaagt gtgttaagcg cttgtggaca agaaaaagaa
     7261 gcggtgacaa caggcacaag tatctttaac gggacctgca atggtttagt taacagtcgg
     7321 ttagattact tattttggct cttcgtcaat gagtgttggt gaagaaattc aatagaataa
     7381 tcgagatact cacacggcta gacagctatc ttgtctagcc gtgttgttgt tctggcttta
     7441 gtcagttggg tagtattctt agttttctta aaatattttc ctcgatataa aaagattcgt
     7501 tctcggtagt tttgaaagtt tctatagcca taggcaattc gttttagtac tttgatatgg
     7561 ttattcaaac attctatagg gccgttggaa tagggaacgc gcaacgctcg tttgatttct
     7621 gtttggtatt tcttgaaggt cgtgaacact ggttggtagt gctctggcaa ctccttgtag
     7681 tcttctttta ggagcgcgac gaattcagga acatcttgtc ttctgataac ggaaagaaaa
     7741 tcctggtaga cttcgtagcc tcgctttaag gaatcatcat aagataatag ccgatcgact
     7801 atctctgctt ctgtcagatg atctcgaaat gacggacgcc agtagcgatg ctgacctttc
     7861 aattcccacg cattcttttg aagtagtttc cagtatttct ttaagtgctt cgaccgacga
     7921 tccccttttt taaaggtctt cattacttga attcggtggt tggtaaaagc ccgaccaatg
     7981 tgttggctaa tatgaaagcg atcggcgacg attcgggcat tcggaaaaca ctctttcacc
     8041 aatgtgcgat agggtgtata gaaatctgaa accactagac gcacttgttc acggactttt
     8101 atagggtagc gcaagaaata gtcgcgtaaa ggattgagtt gccgattttc cacaatatca
     8161 atcagttgat gggtcttgcc gtccatcatg acaaagctca tggctcccga gacatttttc
     8221 actgatttga attcatcgaa acacaccact tctggtaaca gctggctcaa agaaatggtt
     8281 ttaggccgaa ggctgcgaag tattcgaatg acagtggtcg gagaaatgtg cttcatacgt
     8341 gcgatcaaag acatagaaag aggttcgctt aatagctcaa gaatggcttg tttgactctg
     8401 cgagcaatgg agcagcgacg atcactaact gaatcttctg ctaaaaaagt ctttccacag
     8461 tgtttacatt tgaagcgctg tttgttaatc cgcagaatgg tcttgtagtt actgacatca
     8521 ttcaataaga tggatacttt tttccagccc tatttaatga tcgtttgttc attttgatag
     8581 tggcgatgaa agcattcctc cggttgatag gtcaatgtgc catcaaaaac aaaacatgtt
     8641 tcgtcattga ttcgctcttt gcgaaaggca tcttcatgaa agataagatt taggtctaga
     8701 atatctagta actctttggt aaactctgaa taggacatct tgaaacactc ctttgaatgg
     8761 ttttcgtcga ctttattcta aaggatttta aggtgtctgt ttgcgtttat tagaaaaaag
     8821 aaaaagtatt ggcaacagaa ggcgtcacca acactagata ttatagatcc cttattttct
     8881 tcgcttcaaa ttgtcaagga gtcatcataa attttgtatg gattcttttg tttgggtagt
     8941 agtcttctaa ataatcttgg attaacacct tcatctctat tttactttta tatttgttgg
     9001 agtcgattaa ttctcatttg attgatcgat gaaacgcttc aattactgca ttgtcaacag
     9061 gagtcccagt ttggctcact gaatgtgtga tgtggtggtc gttcaacagc tcttgataaa
     9121 taaaagaccg atgctggcta cctctatcgg aatgaattac cgtaggcaat tctccttaat
     9181 aaatttgtaa tggacggacg acaatctctt ttttcatgtg tgaatctacc atatagtaac
     9241 gtagaatacg agttgctaag tcaatatagg tggacaaata gaggcgaccg tcattacatg
     9301 gaatgtaagt aatatccatc acccaaacag catcaatttg gttctgttca aattatcgat
     9361 tcaacatttt tttaccattt ctttgattgt tttttctcta ccatgagaag atttgcgtcg
     9421 atgaaatcct cttgtgcata aattcatttc acgcataaga acagctacaa cacgtttatt
     9481 gatttcgatt ccttcatcgt aaagtttttg agtgatccct ggagatccgt atcgatcttt
     9541 gtgttcgtag aacactcgtc ttcctctttt agtcgtttat tttcctgttc aagaatgtag
     9601 aaatctgctt tatcaggtaa tctttttcct tgtccagcaa aagcattttt cccgtatcga
     9661 cgatattctg aaacccatcg ggaaattgtt ggacgagaga tattgtattc ttcagcaatt
     9721 ttcttggtag ttactttttt ctcaaggata tcctgtgaaa tctttagttt aaatttacga
     9781 tcatatgttt ttctcaatag agttcattcc ttccggtaac gtaactgata gtcaagaaaa
     9841 gtgtatcata gcccaactta gtatcagggt ttgtcaacta aactgtggaa gttgatagat
     9901 aagagttttt aacaaccaaa attctcttga ctatttttga aatcagacaa attttgattg
     9961 gacacatagt tgaataaatc taccgtcgtt acggaaggta aatcgcatgc ttttcaattc
    10021 tagaggagaa gtcctcgttg aagtaccata gcccagttct ggattcgacc tcctgcccac
    10081 ttcatacgta aataaagtaa ttttaggagt gagactgtga caaaagttat ttttaagcta
    10141 aaaacgaatt aaaaaacgtt gataattaaa atcattcgtt ttagattcta tgaatcatta
    10201 tagaacgc
//
LOCUS       DAZKCW010000076         9955 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000076 DAZKCW010000000
VERSION     DAZKCW010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.079"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..439)
                     /locus_tag="ACG84Z_002369"
     CDS             complement(<1..439)
                     /locus_tag="ACG84Z_002369"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9163173.1"
                     /translation="MEEFGIDSISRTEALDFQADYEYELDQITMIPEIHQLLLALHKN
                     RIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGAAENSYEGNVKNLQSY
                     QNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRHK"
     gene            complement(662..1429)
                     /locus_tag="ACG84Z_002370"
     CDS             complement(662..1429)
                     /locus_tag="ACG84Z_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFP9163174.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1917..2342
                     /gene="lacA"
                     /locus_tag="ACG84Z_002371"
     CDS             1917..2342
                     /gene="lacA"
                     /locus_tag="ACG84Z_002371"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFP9163175.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2359..2874
                     /gene="lacB"
                     /locus_tag="ACG84Z_002372"
     CDS             2359..2874
                     /gene="lacB"
                     /locus_tag="ACG84Z_002372"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFP9163176.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2885..3817
                     /gene="lacC"
                     /locus_tag="ACG84Z_002373"
     CDS             2885..3817
                     /gene="lacC"
                     /locus_tag="ACG84Z_002373"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFP9163177.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTVSHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3820..4800
                     /gene="lacD"
                     /locus_tag="ACG84Z_002374"
     CDS             3820..4800
                     /gene="lacD"
                     /locus_tag="ACG84Z_002374"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFP9163178.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4828..5145
                     /locus_tag="ACG84Z_002375"
     CDS             4828..5145
                     /locus_tag="ACG84Z_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFP9163179.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5145..6851
                     /locus_tag="ACG84Z_002376"
     CDS             5145..6851
                     /locus_tag="ACG84Z_002376"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HFP9163180.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTVLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            6993..8399
                     /gene="lacG"
                     /locus_tag="ACG84Z_002377"
     CDS             6993..8399
                     /gene="lacG"
                     /locus_tag="ACG84Z_002377"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFP9163181.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8422..8694
                     /locus_tag="ACG84Z_002378"
     CDS             8422..8694
                     /locus_tag="ACG84Z_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HFP9163182.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            8715..9614
                     /locus_tag="ACG84Z_002379"
     CDS             8715..9614
                     /locus_tag="ACG84Z_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFP9163183.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3138 a         1678 c         1996 g         3143 t
ORIGIN      
        1 gtttatgacg acttttggaa gtaaaaatcc atccattatc tttataatca ggattgaatc
       61 ttatatgttg gtgatttaac tcaatttcct ctttaagaat ttctatagcc cttttagata
      121 attggacatt ttggtaactt tgtaagtttt ttacattacc ttcatagcta ttttctgcag
      181 ctcctccgtg agtggactga ctaatgatga tattttgctt ttcaaaatat tgataggcac
      241 caatattttg gagttttcga ctctgtaagt caacagggcc attagttaga atacctattg
      301 ggatgcggtt tttatgtaga gccagtagta gttgatgtat ctcaggaatc atcgtaatct
      361 gatcgagttc atattcatag tcagcttgga agtctagagc ttctgtccta gaaatactat
      421 cgatgccaaa ttcttccata gtcttctgac agcgaaaaat tctaagctgc tcaatactga
      481 tgagtttttc gtgtatttag gaaaagcaac atcagaccaa catctgaaac gtttgtaaat
      541 gttatctatt tgttggatat caatcgttgg aaaacatttc tcaacgctac ttttaaaggg
      601 gagttgatgg tcataaagag tgtcatcaag gtcaaaaaca atatttttat aagtcataat
      661 tctagtccgc ttttaaaata gtagtgtact ggctaaattc ctctaagtgt tgagggctaa
      721 tctggttatc tgtaatgatg gtatcgagtt gatctagatt atagaagtta aagaaatcgt
      781 atcgatcgaa tttagtactg tctactaata agaatttttc tacagcattg tttagggcaa
      841 gttgttgaat cacaccttcc ttgtcactat atgtagcaat agaattatgg gtaacagcat
      901 ttgcactaac aaaagctttg gcaaatctaa ttgcttttaa atttgtcgaa gccattgaac
      961 ctacaaaagc tccagttatt tctctatatt caccgccaag aagcaataaa tcaatggttt
     1021 cgctatcatt tagaatcaag aacacaggga gactatttgt aatgacacga attttataac
     1081 ctttacgacc tttcaattct aatgccagtt gttcaagtgt agttccgggt ccaataaaaa
     1141 tagtatcgcc atctttgatt aaagagcagg cttttttagc aatgtcaatt ttttcttttg
     1201 tatttagact tttcttctcg atatgtgtct tttcaagtgg ctttttagag gaaagtaatt
     1261 gtgcaccacc atgagtacgt gttaaaagtc catcagcttc tagagcatca aggtctctac
     1321 gggctgtcat atcggaaata tctagttcat ctattatttc ttttatggtt atggtcccat
     1381 caatctttaa catatctaaa attttttcta atcgtcgttt tttgttcata tgaagaccct
     1441 tctttcataa agtaattttt ttccaaagat aattctcttt taattgtatc ataaaagaca
     1501 atattttcaa ggtaaaacaa acaatttcaa acaaaaacaa atgttagatg atgaaataag
     1561 aacagtggat tgacgtatat tagcttaggt cagattttgt ataagacgaa aataaagtag
     1621 gacctcttaa tcagtaagtt atagaaagta aaagactttt gtaatacttg aatagatatt
     1681 tcacgtccat tttgtgatgg attaaatgaa caaaaatgaa caataattta acggtgttat
     1741 ctatttttta aaaaaacaaa taaaaaaaca aaaaataaac aaaaaagtgt tgctttttgt
     1801 ttgaatgctt gatattatat aaacaaagaa atgatgaaaa cgttttttcg aacattttgc
     1861 aaaatgtttt ctacttctac gtagcatttc tttctaaaat ttaggaggtg gtcaaaatgg
     1921 ctattgttgt tggtgcagat ctcaaaggta cgagattaaa agatgttgtg aaaaattttc
     1981 ttgtagaaga aggttttgag gtaattgatg tgactaagga cggacaagat tttgttgatg
     2041 ttaccttggc agttgcctct gaagtaaata aagatgagca aaacttaggt attgtaattg
     2101 atgcttatgg agctggtcca ttcatggtag caactaaaat taaaggtatg gttgcagcag
     2161 aagtttcaga tgaacgctca gcttatatga cacgtggaca taacaattca cgaatgatta
     2221 cggttggcgc tgaaatcgtc ggtgatgagc ttgctaaaaa catcgctaaa ggtttcgtca
     2281 atggtaaata tgatggcgga cgtcatcaaa tccgagtaga tatgcttaac aaaatgtgtt
     2341 aaggaaagga gttaaggaat gagaatcgca attggatgtg accacattgt cacagatgaa
     2401 aaaatggcag tatcagaatt cttgaaatca aaaggacatg aggtccttga tttcgggaca
     2461 tatgaccacg cacgtactca ctaccctatc tatggtaaaa aagtcggtga agcagtagta
     2521 agtggtcaag cagacttggg agtatgtatc tgtggtacag gtgtcggcat taacaatgca
     2581 gtcaataaag ttccaggtgt tcgctcagcg ttggttcgtg atatgacatc agctatatat
     2641 gcaaaagaag agttaaatgc gaatgttatc ggtttcggtg gaaagattac tggtggtctt
     2701 cttatgaatg acatcattga agctttcatt gaagctgagt acaaaccaac agaagaaaat
     2761 aaaaaattga ttgcaaaaat cgaacacgtt gaaacacata atgcacatca agcagatgaa
     2821 gatttcttta cagaattcct tgaaagatgg gaccgtggtg actaccacga ttaaggtata
     2881 acaaatgatt ctgacagtca cactaaatcc ttcagtagac atctcttatc ctctagaaac
     2941 attgaaaatt gatacagtga atagggtgaa agatgttagt aagacagctg gtggaaaagg
     3001 cttaaatgtt actagagtct tgtatgaatc tggtgataaa gttactgcta caggtttctt
     3061 aggtggtaaa attggtgaat ttattgaaag cgaattagaa caatctcctg ttagtccagc
     3121 tttttataaa atctcaggaa acactagaaa ctgtattgct atcttacacg agggtaacca
     3181 aacagaaatt ttggaacaag gaccaacagt ttctcatgaa gaagcagaag gttttcttga
     3241 ccactatagc aatcttatta aacaatcaga agttgtgaca atttcaggaa gtttaccttc
     3301 aggacttccc aacgattatt atgaaaaact tatccaactt gcttcggatg aaggagtagc
     3361 agtcgttttg gattgttcag gtgcacctct tgaaacagtt ctaaaatcgt cggctaaacc
     3421 tactgccatc aaacctaata atgaggaact ttcacagttg cttggaaaag aagtaacaaa
     3481 agatattgaa gaactcaaag acgttcttaa agagtcactt tttagtggta tcgaatggat
     3541 agtggtctca ttaggtcgaa acggtgcctt tgcaaaacat ggtgatgttt tctataaggt
     3601 agatattcct gatatcccag ttgttaatcc agtcggatca ggggactcaa cggtagctgg
     3661 tattgcatca gctttaaata gtaaaaaaag tgacgctgac ttattaaaac atgcgatgac
     3721 attgggtatg ttaaatgctc aagaaacaat gacagggcat gtgaatatga ctaattacga
     3781 aacactaaac tcacaaattg gagtaaaaga ggtataaaaa tggtacttac agaacagaaa
     3841 cgcaaatctt tggaaaaaat ttcagataaa aacggtgtta tctcagcttt ggcatttgac
     3901 caacgtggtg ctttgaaacg tttgatggca cagtatcaag atacagaacc aactgtagct
     3961 caaatggaag aactaaaggt tttggttgct gatgaactta caaaatacgc ttcttcaatg
     4021 ttgcttgacc ctgaatatgg acttccagca acaaaagcat tggataaaga agcaggtctt
     4081 cttcttgcct atgaaaaaac aggttatgat acatcaagta caaaacgttt gcctgactgc
     4141 ttggatgttt ggtctgcaaa acgtatcaaa gagcaaggcg ctgatgccgt taagttcttg
     4201 ctttactatg atgtagacag ctcagatgaa cttaaccaac aaaaacaagc ttatattgaa
     4261 cgtgttggtt ctgaatgtgt cgctgaagat attcctttct tcttggaaat ccttgcttat
     4321 gatgaagaaa tctcagatgc aggttctgtt gaatatgcaa aagtgaaacc tcgcaaagtc
     4381 attgaagcga tgaaagtttt ctctgatcca cgctttaaca ttgatgttct taaagtagaa
     4441 gtaccagtta acgttaaata tgtcgaaggt tttgctgatg gtgaagtggt ttacagtaaa
     4501 gctgaagctg ctgacttctt taaagcacaa gaagaagcga ctaaccttcc atacatctac
     4561 ctaagtgcag gtgtatctgc taaattgttc caagaaacat tgcaatttgc tcacgactca
     4621 ggtgccaagt ttaatggtgt gctttgtgga cgtgctactt gggcaggatc tgtagaacct
     4681 tacatcaaag aaggtgaaaa agcagcacgt gaatggttgc gtactactgg attcgaaaat
     4741 attgatgaac ttaacaaagt tcttgttaaa acagctagtc catggactga taaagtatag
     4801 taaaaacata aaacggagga tattgttatg aacagagaag agatgactct cttagggttt
     4861 gaaattgttg cttatgctgg agatgctcgc tctaaacttt tagaagcgct taaagcggct
     4921 gaaaatggtg atttcgctaa ggcagatagt cttgtagtag aagcaggaag ctgtattgca
     4981 gaggctcaca attctcagac agctatgttg gctcgagaag cttctgggga ggaacttcca
     5041 tacagcgtta ccatgatgca tggtcaggac cacttaatga ctactgtctt attaaaagat
     5101 gtgattcatc acctcatcga actttataaa agaggagcaa aataatgcat aaactcattg
     5161 aacttattga gaaagggaaa ccgttctttg agaaaatctc tcgaaacatc tatcttcgtg
     5221 ctattcgtga tggatttatc gctggtatgc cagtcatcct tttctcatct atctttatcc
     5281 ttattgccta tgtcccaaat gcttggggat tccactggtc aaaagacatt gagaccttct
     5341 tgatgactcc ttatagctat tcgatgggta tcctagcatt ctttgttggt ggtactaccg
     5401 ctaaagcttt gacggactca atgaaccgtg acctacctgc gaccaatcag attaacttct
     5461 tatctacgat gctagcgtct atggtagggt tccttttgat ggcagctgag cctgcaaaag
     5521 aaggaggctt cttgacagcc ttcacgggaa caaaaggtct tttgacagca tttattgcag
     5581 cctttgtgac agttaatgtt tacaaggtct gtgtgaaaaa taatgttact attcgtatgc
     5641 ctgaagaggt tccaccaaat atctctcaag tatttaaaga cttgattcca ttcactgtag
     5701 cggttgttct cctttatgga tttgaactca ttgttaaggg aactcttggt gtaaccgttg
     5761 cagaatcaat cggtaccgtt cttgctcctc tcttctcagc tgcagatggt taccttggaa
     5821 ttacacttat ctttggtgct tatgccttct tctggtttgt tggtatccac ggtccttcaa
     5881 ttgtcgaacc agcaatcgct gctatcactt atgccaatat cgatgccaac ttgcatctta
     5941 tccaagctgg acaacatgca gataaagtta tcacttctgg tactcaaatg tttattgtta
     6001 ccatgggtgg aacaggagct acattgattg ttccattctt gttcatgtgg atttgtaaat
     6061 cagaacgtaa ccgtgccatc ggacgtgcct cagttgttcc aacattcttt ggggttaatg
     6121 agccaatctt atttggtgca ccaatcgtat tgaatccgat tttctttgta ccgttcattt
     6181 tcgctccgat tgtcaacgtt tggatcttta aattctttgt tgacacattg aacatgaact
     6241 cattctctgc caaccttcca tgggttactc ctggtccgtt gggaattgta ctcggtacta
     6301 acttccaagt tctatcattt atcttagccg gactcttggt agttgttgat actatcattt
     6361 attacccatt tgttaaggta tacgatgaac aaattcttga agaagaacgt tctggtaaaa
     6421 caaacgatgc tcttaaagaa aaagtagctg caaacttcaa tactgctaaa gcagatgccg
     6481 ttcttggaaa agcaggcgtt gctaaagaag atgtagcagc aaacaataat atcacaaaag
     6541 aaactaatgt ccttgttctt tgtgcaggtg gaggtacaag tggcttgctt gccaatgcct
     6601 tgaacaaagc agcagcagaa tacaatgttc cagtcaaagc ggcagcgggt agttacggtg
     6661 ctcaccgtga aatgttgcca gagtttgact tggttatctt ggctccacag gtcgcttcaa
     6721 acttcgatga tatgaaggct gaaacggata aattgggcat taaacttgca aaaactgaag
     6781 gagctcaata tatcaaattg acacgtgatg gacaaggtgc tcttgcattt gttcaacaac
     6841 agtttgatta ataaatttgt aaaagttatt tgagacgaga ttattctttc agttccttat
     6901 aatattgtta accatatcat tgcatttcat ttccttggtt tccggaactc agaatatcgt
     6961 ctcaaatgct ttttttgaaa ggatttatag ttatgactaa aacacttcct aaagatttta
     7021 tttttggtgg tgctacagct gcttatcaag cagaaggtgc gactcacacg gatggtaaag
     7081 gcccagttgc atgggataag tatcttgaag acaattattg gtacacagca gagcctgcaa
     7141 gtgattttta ccataaatat cctgttgatt tagaattagc tgaaaaatat ggcgttaatg
     7201 gtattcgtat ttcaattgcc tggtctcgta ttttcccaac tggctatggc gaagtaaatg
     7261 aaaaaggtgt tgaattctac cataatcttt ttgccgagtg ccacaaacgt catgttgagc
     7321 cattcgtgac tttgcaccac tttgacacac cagaagttct tcactcagat ggagatttct
     7381 taaaccgcga aaatatagaa cactttgtag attatgccgc tttctgtttt gaagagttcc
     7441 cagaagtaaa ctactggaca actttcaatg aaattggccc aattggagat ggtcaatact
     7501 tggttggtaa attccctcca ggcattcaat atgatcttgc caaagtcttc caatcacacc
     7561 acaatatgat ggtttctcat gcacgtgctg tgaaattgta taaagataaa ggttataaag
     7621 gcgaaattgg tgtagtacat gcgttgccaa ccaaataccc ttatgatcca gaaaatccag
     7681 cagatgttcg tgccgctgag ttagaagata tcatccataa caaatttatc ttggatgcaa
     7741 cctaccttgg acactattca gataaaacga tggaaggggt caaccacatc ctagctgaaa
     7801 atggtggaga acttgatctt cgtgatgaag acttccaagc acttgaagca gctaaagatt
     7861 tgaacgattt ccttggtatc aactactaca tgagtgattg gatgcaagcc tttgatggtg
     7921 agactgaaat cattcacaat ggtaagggtg aaaaaggaag ttctaagtac cagattaaag
     7981 gtgttggtcg ccgaatcgca ccagattatg tgcctagaac ggattgggac tggattattt
     8041 atcctgaagg cttgtatgac caaatcatgc gagtgaaaaa tgattatcca aactacaaga
     8101 agatttacat cactgaaaac ggtcttggat acaaagatga gtttgtagat aataccgttt
     8161 atgatgatgg tcgtattgat tacgtgaaga aacacttgga agttttatca gacgcaattg
     8221 cggatggtgc aaatgttaaa ggttacttca tctggtcact tatggatgtc ttctcatggt
     8281 caaacggata cgaaaaacgt tatggactat tctatgtaga ctttgacacg caagaacgct
     8341 atcctaagaa atcagctcat tggtataaga aagtagcaga aactcaagtg atagagtaat
     8401 attacttgaa aatgtaaaaa attgttatcc gatactttag aaaaagtaca acacttattt
     8461 agaccaggct ttgaaaaggt atatattgtt agtttcgaag attgtcctat gattcctgag
     8521 cttgaagcta ccccgttgct aaaatgtggt aaatggtatg tttcaactgg aaaagagtgg
     8581 atttgccatt ctgatttaga gttatcagca tttgaatggg aatttttaca atcactcgat
     8641 gtagaaatac gtgagactat tcacttcgag gtaaattatt tgcctttcca ataataaaaa
     8701 gaaaggaatt agttgtgact atcgaattaa aaaacgagta tcttactgtt cagtttaaaa
     8761 cacttggtgg tcaactgact tcgattaaag acaaggatgg gatagagtat ctctggcaag
     8821 ctgatccaaa ttattggaat ggacaggcgc ctattctatt tcctatctgt ggtagtttac
     8881 gaaatgattg ggctatttat agacctcaag aaagaccttt ttttacaggt cttattcgta
     8941 gacatggttt tgttcgaaaa gaagaattta ttctggaaga agtcaatgat aatagcgtga
     9001 cctttagtat taaaccaaat gctgagatgc ttgataatta cctatatcag tttgaactga
     9061 gagttgttta taccttgaat ggtaaatcaa ttagaaccga atttcaggta acgaacttgg
     9121 aaatggaaaa aacaatgcct tactttattg gagcccatcc agcattcaat agtcctttag
     9181 tagaaggtga aaactatgag gattattata ttgaatttag tgaggttgag tcttgctcga
     9241 taccaaagag ttttcctgag acaggattat tagatttgca agatcggaca ccttttttgg
     9301 aaaatcaaaa aattctcgat ttggactact cacttttttc ccatgatgcc attacacttg
     9361 accagctcaa gtctcgtagc gtaacgcttc ggtcaaggaa gtctggtaaa ggtcttcgag
     9421 tagattttga tgattttccg aacttgattc tgtggtctac aactaataaa agtccattca
     9481 ttgctttgga accttggagt ggtctctcca cttcacttga agaaggtaat ttcttagaag
     9541 ataaaagaca ggtaacgaaa atttcacctc aagaaacttc tagaaaaatc tatgatatta
     9601 ctatccttaa ttaaaatttg ttattatttg agtcttcaat aagatttgaa tactcttacc
     9661 ttgtgatgat agattggtct tctccgtgcc agtcttacat cgcaaggttt ttaagttttt
     9721 tgtgggtcta tgtcaactgt agtgggtgac gaaaagctaa tatctaaaga cagtctggta
     9781 gtaaaaaata agattattta ctacttcttg atttaaaata atagtggagc cattaatttg
     9841 tggcaaattt aatttaatat tttgcctcaa attagccaca ctttttatag aactaagagg
     9901 aaaaatgaaa ttttcttcct attaatatag ttgtttgaaa tcttaaatat agcgt
//
LOCUS       DAZKCW010000077         9722 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000077 DAZKCW010000000
VERSION     DAZKCW010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.080"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            33..656
                     /locus_tag="ACG84Z_002380"
     CDS             33..656
                     /locus_tag="ACG84Z_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163184.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /gene="trpX"
                     /locus_tag="ACG84Z_002381"
     CDS             1106..2155
                     /gene="trpX"
                     /locus_tag="ACG84Z_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9163185.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="ACG84Z_002382"
     CDS             2152..3033
                     /locus_tag="ACG84Z_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9163186.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="ACG84Z_002383"
     CDS             3036..3806
                     /locus_tag="ACG84Z_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163187.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="ACG84Z_002384"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="ACG84Z_002384"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFP9163188.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="ACG84Z_002385"
     CDS             5117..6280
                     /locus_tag="ACG84Z_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFP9163189.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="ACG84Z_002386"
     CDS             6397..6807
                     /locus_tag="ACG84Z_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFP9163190.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="ACG84Z_002387"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="ACG84Z_002387"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFP9163191.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="ACG84Z_002388"
     CDS             9380..9664
                     /locus_tag="ACG84Z_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163192.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
BASE COUNT         3372 a         1648 c         2087 g         2615 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tc
//
LOCUS       DAZKCW010000078         9694 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000078 DAZKCW010000000
VERSION     DAZKCW010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.081"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..195)
                     /locus_tag="ACG84Z_002389"
     CDS             complement(<1..195)
                     /locus_tag="ACG84Z_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163193.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNY"
     gene            complement(211..825)
                     /locus_tag="ACG84Z_002390"
     CDS             complement(211..825)
                     /locus_tag="ACG84Z_002390"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFP9163194.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(972..1655)
                     /locus_tag="ACG84Z_002391"
     CDS             complement(972..1655)
                     /locus_tag="ACG84Z_002391"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFP9163195.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(1764..2222)
                     /locus_tag="ACG84Z_002392"
     CDS             complement(1764..2222)
                     /locus_tag="ACG84Z_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFP9163196.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(2306..4069)
                     /locus_tag="ACG84Z_002393"
     CDS             complement(2306..4069)
                     /locus_tag="ACG84Z_002393"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFP9163197.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(4290..5750)
                     /locus_tag="ACG84Z_002394"
     CDS             complement(4290..5750)
                     /locus_tag="ACG84Z_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163198.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(5958..6884)
                     /gene="glsA"
                     /locus_tag="ACG84Z_002395"
     CDS             complement(5958..6884)
                     /gene="glsA"
                     /locus_tag="ACG84Z_002395"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFP9163199.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(6907..8334)
                     /locus_tag="ACG84Z_002396"
     CDS             complement(6907..8334)
                     /locus_tag="ACG84Z_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFP9163200.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(8365..9579)
                     /locus_tag="ACG84Z_002397"
     CDS             complement(8365..9579)
                     /locus_tag="ACG84Z_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFP9163201.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         2873 a         2026 c         1611 g         3184 t
ORIGIN      
        1 gtaattaaac aatccgctaa tcgtttgatc tggcatttct atttccttac catctaaagt
       61 aacagtagta acgacaaaat ggtcttgcaa tggcggaact tctaagtact gcccttgcag
      121 aaaatcattc actgtttcat attctttttt catttctttt gaatctgtcg atggtttata
      181 gcttattttt aacataacta gtgctccttt ttattcggga cgtgcaatcg tgaaaatttc
      241 tcctattgct gcataatcat ttcctgccaa acggcttaca gcattcaatt ttcttggatc
      301 gatccttcct gtcttatcat catagactgt ttcatttaaa tgatatttct gtacttctag
      361 caaaaataaa tcagctgtta ctttattttt attccgtatc tcgacatgtt catataagga
      421 tgtttcaaaa cgaacttttg cttctgtcaa tgctggtact gaaatgatta ctgaatcagt
      481 taaagtcaag tcagtcaggt acagttcgct ttcctcatta ggcagattgg ctgctgtttt
      541 atttacttct tctacgttgt cctcatcaag gatatggata acagcttctc ttgtctcaag
      601 aatattcttt gctgtgtctt ttactgcatc ttgttttctc tggatcgcca aggataagat
      661 gggtcgattc gaactgacga tattgaagta actgaagggt gcgatattca ctatatcttt
      721 tgctgattta gtcgttacta ctgctactgg tctagggatg actgaaccaa tcagcaactt
      781 gtaattttca cgttctgtca attctgaagg actccgttca aacatggttt cgccttcttt
      841 ctataaaatt cgttaaaaag cagatcttga agacaaaatg aaaagtaatg cttttttcat
      901 cttcttagaa tctgctttaa actatctatc aatttttctt ttttgtcaag aatctgtgcc
      961 gtgcgtgttt tttagttatt tgctttactt gcggcttcga catatctttt agtgatcaat
     1021 tgcggacggg tgataataga tccaactacg actgaaaaag cacctaattc atatgctttc
     1081 tctacttgtt caggagagtc agtatgtcct tccataatta ctgggatatc gacttgttct
     1141 atgatttgat tcaataaatc aaaatcaggt gtctgcgtct ttcgtgaata ttctgtatag
     1201 cctgctaaag tcgtagacaa aagatcaaaa ccatcttctt gcgcttgaag cgcttcctca
     1261 aaagtcgaaa tatctgccat agctaaccga ccgtgttcgt gaatcatttg gacaagttca
     1321 gcagttgttt tttctgtcgg acgtttacga gaagttgcat ccagtgcaat gatttctgct
     1381 tgcgtctcca aaagttcttc cacttctttt tctgtcgcag taataaacac ttctgaccca
     1441 tcgtaatctc ttttgataat ccctattacc ggtaaatcaa cgattcgctt gatttcattg
     1501 atatcttctg tcgtatttgc tcgaatacca actgctccgc cttcttttgc agccaaagcc
     1561 attctcccca taataaaaga actgtgtagc ggctcgtttt ccaaagcttg acaagaaacg
     1621 acgactccgc ctttgatttg ttccagtgta tccacaatat ctcctccagt aatgttatat
     1681 aaaaatacag cttcatataa aaatgtaacc cttttctatt caggagacaa taatgagcta
     1741 tttctttcag cagacctttc ttactaaaag aaaattactt caaattcttc gtatacgacc
     1801 agcttctctt ctgtaaattc tatgttcaac gcttctttat aagcatgttt aaaaaactca
     1861 gcatggactt tccgccaata agctaatgtc cgatcccctt ctccttcttt ccaagcatgc
     1921 tctttcgtga cttcactaaa aggcaagatg gtcacattta tatttttgat gatacaaact
     1981 ggttcatttt ttccattcag gaccacgtct aattgaccaa cttttggtaa aggctcattc
     2041 tcttgtttat acagatcgta accacttgat gtaccagtct ttatcttttt tacaactagt
     2101 tcgctcaact cgtctgccat tttttctgta tccccaaatg aaaagaaacc taatttttct
     2161 gattgataac taggatattt ttcttggaac tttttgacat attcttctac ttgctgatac
     2221 ataacatcca cccctttgct ttttataatg aaaaaaccat ccagatacta gtataaacaa
     2281 ttatctggat ggtgagcata atgaattatt gaatattcaa gacacgcaga ctatcttcaa
     2341 cgatttgttt tggtgttaaa tgataacgtt cataaagctg ccctacagga acgctatccg
     2401 tgaattcttt ctctgcacca aaatttaata cgttcattga agaatcacca taataacgac
     2461 tgatattttc gccaaatcct cctgacaaac taccatcttc taatgtgatg actaattcgt
     2521 gtgtttcttt taatttatct aatgtttcta cgtcattttc tgtgatcgtt cctggattga
     2581 tcaacgttgc ttcgattcct ttttttctaa aagcttttac tgtttctttt cctaattcaa
     2641 gaaaaccgcc taaagctaaa attgctactt ttcctccatt atttactgtt tgataggctg
     2701 gaatactata atcatttgcg atagctgtac catgttctac accatgtgta ggaattcgga
     2761 ttgctacagg ctgcgctgtt tgttcgaacg cccaatctag catagagatc atatcctctt
     2821 ttgttgctgg agcaagatat ttgatgttcg ggatacttga taagtaagga atgtcaaatg
     2881 ttccttggtg tgttcggtca ctagctgaga tcgttccgcc accgactaaa ataatcactg
     2941 gattctcgtt gatcgctaaa tcatgtgata attgatcata tgcccgttgc aagaaagtac
     3001 ttgattggaa gacgactgga cgtactccct gagaagccaa agcagaagcg aaagtgatag
     3061 agtgctgttc agcgatcccc acgtcaaaat aatgatctgg atgtttttct tggaatgttt
     3121 tcagtccaaa ggcgcctggt atcgctgcat tgactgcggc aataggagct gtacttgttt
     3181 gcattttctt atccaaataa tccatgatga tcatattaaa tgtttctcca gaagttactt
     3241 gctttgcctc cccggtggac agatcaaatg gtacatgcca atgatatttc attttattat
     3301 cgattgccgg ctgataaccg cgaccttttt ccgtatggac gtgaagtaca atcggatgat
     3361 caatatcttt tacttcttca aataaacgga tcaccgtttc cagatcgttt ccattatcca
     3421 cgtaacgata atcaaatccc attgctttaa ataggttatt gctgctttta ccgttggttt
     3481 gacgaagctc agctaagttt ttatataaac tgccatgatt ctcatcaata gacatctcat
     3541 tatcgtttac taatacgatt agattggatt gtaaaacacc accattgttc aatccttcaa
     3601 aagctaagcc accacttagg gagccgtcac cgataaatgc taccacattt cctgattctt
     3661 tcttcagatc tctcgcttta gctaaacctg ttgctaagct gatagatgta gatgtgtgcc
     3721 ccactgtaaa atagtcatgt ttactttcat gttggttgga atatccgctc acttcacggt
     3781 aatgtccttt ttcaaaacca ttttttcgac cagttaaaag cttatgacca taagactgat
     3841 gggaaacatc ccaaacgatt ttatcctttg gtgaatcaaa tacataatga aacgcaatcg
     3901 ttaattctac tacacctaga ttcggaccaa cgtgcccacc tacatcgctg tccttttgca
     3961 agattttttg gcgcatctct tctgccaact gtttcatttc ctcaacagat aattttttga
     4021 catctgcggg gctattgatt gcatccaata catgtaatac tgtactcata atacattctc
     4081 tcctccgtac tatcttcttt taatgaaaat agatttgtta cactttatct attctactac
     4141 ttagagttga ctctaagtca atagcatttt aaaaaaattt cagagaaagc ttgttatata
     4201 agtagatctt cgcacgaatc aggactcaaa taaaaacctt ctacagacaa ttaaaaagct
     4261 ttgtagaagg tctcctaatt aaggtctcat caagaaatat gtttttttaa taggtgaagt
     4321 tcctgagcaa tatgatacaa atggatgttt gcacctttta atgagattgg atagatcttt
     4381 gtcttttcag tttctaatcc attttgatag ctagcagcat cgcacaaaac cactcttttt
     4441 ttcgcacata gacattcatc aggcaattct tctaatgaac gaaataaaat aggatttatt
     4501 tcagcgatgc cttcttccgc atacaaatga aattgggttc gataaaaaaa ttgtttgact
     4561 gaactttctg aaacaacaaa aatttctatt tcctgtctcc ccgcttgttc actgttgatc
     4621 aaagaaagac ttttgacgaa ttttcgaatg aaattttcat tccatcttag ttggatttga
     4681 tttttctttt tccactcttc caatatttct acaatttttc cgtacagaag ttgttctttt
     4741 tctgatagaa gatagatcct ttccggtaaa aatacttgtc catctgccca caacgtacgg
     4801 acaaattgta aaaaggattg cttgaaaata aaattttctg catcgtcgat ttcagcgata
     4861 ctaataatct gtaaaatcaa ttcattcagt gataggtcat tgagaacaaa atttttataa
     4921 acaacttcga aatcttttct taacagctcc atgttctcat tggtataatt tctactgttg
     4981 aacaaagaaa aaatataata gacatcttct tcttgtaagt ctagaattcc tttttgctct
     5041 tccaatcctt gacagactaa ttgaaataac ggcttcgttt ctgcgctttt cttatcttct
     5101 tctttcagtc caaggggaaa tgcctttctt ccgattgcga tctctattcc tcgtatgata
     5161 aaggactttt catcttccga atatcttctt ttaaaaaaat gagtctctac ataatcaatc
     5221 aactcgttac aagcttcttc tacatacgga tttttatttt catagccttc ccaattgaca
     5281 taacgtacta aagctagcaa gatgttccgc gagtcaaatt ctgggataat gatttcttta
     5341 tttttcaaat aatcattttc tttaaaaaaa tccaatacga tttttttgat tgtatatact
     5401 ttgctcaaag aaataaattc aagatcagcc agttctgtac tcgtgaatat accattaaaa
     5461 taataactta aaaactttaa aaaataagat tgaccgtaca gaaactgtgt gagctcagaa
     5521 agagcaatac catgtttgaa tacgagttta tacttatgct tctctcttac ttgttctttt
     5581 atacaatatt ctagacactc ggctagactt tctagatcgt gaaggatcgt tggtgtagtc
     5641 acccttagag aaatagctgt ttgttcgatg tctatttctt ggaattcaaa taattgttca
     5701 cacagataca cttttctaaa tatatttcgc tcgatgtaat tttccagcat tcctgataca
     5761 cgcctccagt ttttcttatg attttattta atcatatctg taaatcgtat ttttgtttcc
     5821 tttttattta gaaaagccct ttcaaaaacc aataaaaaaa gaaactggga caaaagtcaa
     5881 acaagctcac aatttcagcc tcattgtagg tagctttgag ccgtttggac ttttacccca
     5941 gcctctttca agaatggtta ttcaaagatg tcagcgtcta gttctttgac tacatctttc
     6001 aacaattgga taccagctgc gctgttacca aatggatcta gtgccgggct gaagacacct
     6061 atgccgtaac gatttggcac agctgccatc aacccgccgc ctacaccgct ttttgcaggt
     6121 acaccaacat ggacggaaaa ctctcctgat tcatcataca aaccagcagt tgtcataatt
     6181 gatttgacga ttgtagcact ttcttcagta atgatttgtt tgccattcca aggagcaatt
     6241 cctttatttg ccagcacagc agctaatttt gctatgcctg tagcggtgac attgagggag
     6301 cattgtctga aataagcatc gagtatctcc ggtacgtctc cttcgatcat ttgattacct
     6361 ttcatatagt aagcaagaga gcgattgata tcacctgttc ttgattcaga atgatagatt
     6421 tcttcattca atgtgatatt aggatcatca cagatctctt tcataaatga caagattcgc
     6481 tcaaattttt catctgcatc tttaccggca atcaacgagg ttgttgcaat cgctcctgca
     6541 ttaacaaaag gattcattgg atgtttgcga tgattgattt ccatattcat gatagaattg
     6601 aaggcaaaac cggttggttc cgtgttgatt gtttgaaaga ctttttctat tccgttgtct
     6661 ttgattgcta ataacaatac gggaactttt gacatgcttt cgatggcaaa gcgcacatcg
     6721 gcgtctcctc cctcaatcag ttgttttgta tccaaatcat aaatcgccat acctaattgt
     6781 ttgggatcca cttcagctaa tgctggaatg taatccgcca cttgtcctgt ttgataatag
     6841 tggaaatttt ttccaatcaa ttgttctaat tcttttactt ccatttgaat aaccagcttt
     6901 cattttttat ttttctgcat gctggaattt atgacggcat gcgtagatcg taaatggaat
     6961 aactaagacg ataagataag aaacaatcag aatcgtttca taaatcccat gctgtccagc
     7021 tgcgatacta gcaggtggaa caaatgagat acaaaaagca aaaagtgaag tcaaaagacc
     7081 taaacaagca acgattactt ttacaacttt tccgcctgga acctgatagg ctctttcaag
     7141 actgtcatct ttaaaaacca gcttcaaata gcccgcgaaa aacataaagt acaacatcag
     7201 gtagattaca acagtcaatg acatcgctgc aagaaatgaa agattattcc ccccgccgct
     7261 taatgtaaag acggctgccc agattgttgc aacgatccca tttgcgatca tcaaatgagc
     7321 aggaacaccg tgtgtgtttt cttttgcaaa atattcagga agtaatcctt cttctgctgc
     7381 tacgtgaagt gcttttgaag gagaggttac ccaagaagca atttctccga tgacacctaa
     7441 acaaacaaga atcgcaagaa ttttcgcaat ccatgcaaga tttggatcaa tgtgtcttaa
     7501 taggaattct aacgattgaa tcacccctgt attaagagac aaaccatgtt gaggtactgt
     7561 agtagcgacg gtcaatccgc caaaagtatc taaaatgatt gccagaataa ccaatacaaa
     7621 cattgctaat ggataatcct ttttagggtt ttccatttca tttgcatgac tggcagatgt
     7681 ttctacgccc atatatgcta aaataaagga aacaaaaaca accagcgtag gcaatttcga
     7741 aaaatcagga atcaatgttt tcatagacag tatcgtttgt agtggagcgc ctgaagcgac
     7801 ataatggatc cctaagccaa acaagactaa tgctggcaac aagataccag ctacaaaacc
     7861 gatccgagca atcaatgaag tgtatttggt tccttttaac tgtgagagta aaatagccca
     7921 gaaaataatc aataggattg ccaatttcag atatttattg ttttgtatag caccaatacc
     7981 cgttgcatag gataatgcac cagttaagaa atacagcatg gtcaagtagc caactgttat
     8041 ctcaaaccat tggaaaaaga ttgcggcaaa accgaatcgt tttcccaatg tgcgactgac
     8101 ccaagtatag acaccgcctt tttcccatcc tttcaccgtt gccatctctg ctgcgcacaa
     8161 tgccacaggg ataaaccata gcaaaccgcc taataacaag aaaaatacta agctgaagcc
     8221 tgaggtcgcg aatgtgggat attcatataa tgaaacgacc attgagatgg tcatagccaa
     8281 aaagccaaag aacgttaatt tttttgcagg aattttcgtt ttgctttgtt gcatgaatct
     8341 tcctcttttc tattttaatt tgtttcaatt gagtttgttg ccaaagaaga aaaagtccaa
     8401 tccttcttct tgttcttctt ttgtagtagt gatcgttgta aagtgcatcg ccgattttaa
     8461 aatcactgtt gtcagcacat aggcatacac ggcagtaatg atgacaccaa tcacttgaat
     8521 ccctaagaag taccagctgc ttggattcgt tagtaaatgg ctgttagatg caaagatccc
     8581 tatcagaatc gtacctgtga atccgcccat gccatgaaca ccccacacat caagtgcatc
     8641 atcccattgt ttctttttac gaaaatcaac agcagcatga cagacgatac ccgcaatgat
     8701 cccaatcagc atggcacttt ttgcttctac ataaccggca caaggcgtaa tggctgccaa
     8761 tccagcaacg gatcctgtta gtacgtcgac aaaatcaaag ccatttcctt ttacttttgc
     8821 aatgatcagc caagtaatca tcgcaaatgc aagagcgatg aatgttgaac caaatgcatt
     8881 gactgcttgt tcatctgctc gaagtgcacc accggaatta aaaccgaacc agccaaacca
     8941 aagcagtcct gtaccgatag cagctgccat aagactgcta tgctgacttc tttctcctaa
     9001 aggaatcttt ctttgaccaa gtgtgaggat acatgctaaa gagccgaatc cagctgtcgt
     9061 gtggatgact gctccaccag cgaaatctct aaatcccatc tgatccaaaa atccgccacc
     9121 ccatatccag tggcaaacag ggaaataaat cagcagattc caaaaaataa caagtataat
     9181 atagcctttt aaattcaatc tccctgcaaa agctcctgtc atcaaaggaa cggtaatcac
     9241 gataaacatc agttggtaaa gaaagaacat taaaaatgga atcgttgcac catgaaacat
     9301 gttggggaag cttgtaacat gtctcatcaa aaagaaatct gccgggtttc caataacacc
     9361 gccgatatcc cgtccaaagg ccaatccgaa tccaccaaat acccacataa tcgttgttat
     9421 cccaacggag agaaaagatt gagacatgat cgttagtata ttattcttcc gtgctaatcc
     9481 gccgtaaaaa aaagctagac caggagtcat caggcaaacc attgctgtac ataaaatcat
     9541 gaatgctgta tctcctgtat tgataggtaa tgtattcatt tttttcgcct cctttctacg
     9601 attacgagta taaaagaagg tgtagttgtt tttttcttct gtttttttga attaatactt
     9661 gcatttataa aagacagaca attaataaaa gctt
//
LOCUS       DAZKCW010000079         9473 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000079 DAZKCW010000000
VERSION     DAZKCW010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.082"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            28..930
                     /gene="gnd"
                     /locus_tag="ACG84Z_002398"
     CDS             28..930
                     /gene="gnd"
                     /locus_tag="ACG84Z_002398"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFP9163202.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKRTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            932..1933
                     /locus_tag="ACG84Z_002399"
     CDS             932..1933
                     /locus_tag="ACG84Z_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFP9163203.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            1930..2214
                     /locus_tag="ACG84Z_002400"
     CDS             1930..2214
                     /locus_tag="ACG84Z_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFP9163204.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            2247..3044
                     /locus_tag="ACG84Z_002401"
     CDS             2247..3044
                     /locus_tag="ACG84Z_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFP9163205.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            3058..3891
                     /locus_tag="ACG84Z_002402"
     CDS             3058..3891
                     /locus_tag="ACG84Z_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFP9163206.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            3909..4766
                     /locus_tag="ACG84Z_002403"
     CDS             3909..4766
                     /locus_tag="ACG84Z_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFP9163207.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            4788..5297
                     /locus_tag="ACG84Z_002404"
     CDS             4788..5297
                     /locus_tag="ACG84Z_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFP9163208.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            5334..5735
                     /locus_tag="ACG84Z_002405"
     CDS             5334..5735
                     /locus_tag="ACG84Z_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163209.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            5847..6200
                     /locus_tag="ACG84Z_002406"
     CDS             5847..6200
                     /locus_tag="ACG84Z_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163210.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVEADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            6234..6677
                     /locus_tag="ACG84Z_002407"
     CDS             6234..6677
                     /locus_tag="ACG84Z_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9163211.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            6694..7779
                     /gene="uxuA"
                     /locus_tag="ACG84Z_002408"
     CDS             6694..7779
                     /gene="uxuA"
                     /locus_tag="ACG84Z_002408"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFP9163212.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            7772..8485
                     /locus_tag="ACG84Z_002409"
     CDS             7772..8485
                     /locus_tag="ACG84Z_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9163213.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(8692..8841)
                     /locus_tag="ACG84Z_002410"
     CDS             complement(8692..8841)
                     /locus_tag="ACG84Z_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163214.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            9237..9437
                     /locus_tag="ACG84Z_002411"
     CDS             9237..9437
                     /locus_tag="ACG84Z_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFP9163215.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         3182 a         1493 c         2107 g         2691 t
ORIGIN      
        1 gagggtataa gaaatggagg cgctatcatg gaaattggtg taattggttt gggaaaaatg
       61 ggattgaatt tagctttaaa cttaaaagag caccatcaca aagtacaagg actcgacatt
      121 tcaagtacag ctgttagtca ggcaagagaa aatgacattc ctgcttatca agagatctct
      181 gaatttctag ctacttttga gcagaaaaaa atcatctggt taatgcttcc tgctggagag
      241 ataaccgaaa acatgttaag aaaacttttt ccaaaactcg gaccaggaga cattattatt
      301 gaaggcggaa actcttatta taaagattca atccgtcgag cagaagagtt tcagaaaaat
      361 gaaatcggtt acttggattg tgggacttct ggaggaatcg aaggagcacg acatcaagcc
      421 tgcttaatga ttggaggaga taaagaaact tttctatccg tggaacaatt attcaaagat
      481 gtagcaattg aaagaggata tctgtatgct ggtgcatccg gaagcggaca cttcttgaaa
      541 atgatccata atggaatcga atatggaatg atgcaagcaa tcggtgaagg attccaactt
      601 gtacaaaaaa gtgagtatgc ttttgacttg gaacaagtcg cacgtgtttg gaatcatggt
      661 tcggtgattc gcggctggct gatggaaatc atggaagatc agttaaacga acatcccaat
      721 ttaagtaatt atcggggaat cgtttctgca tcaggtgaag caaaacggac ggttgaaaca
      781 gcgctagaaa tggctgttcc agttccagta attgcaacta gtttgttcat gaggaatctt
      841 tcacaggaag aagatagttt ttcagcaaaa gtagtttcag cactaagaaa tgggtttggc
      901 ggacatgaaa tagttgaaaa gggtgagtaa aatgccagat tatcatatag caatcgttaa
      961 ttccagcagt ttcggaagag tctttccaca ccacttggaa agattaaagt cagttggaga
     1021 cgttcatttc tttactgttg atcaagagat tccaggaaaa gaactagcgg agttacttaa
     1081 aggattcaat atcattattg caagtgttac gccatttttt cgacgagatt tttttgaaaa
     1141 caaagatgaa ctgctattga tttcccgaca tggtattggt tacaacaata ttgatttaaa
     1201 agcagcaaaa gaacaccaga caatcgtatc tatcatacct gctttagttg aacgaaatgc
     1261 tgtagcagaa aataatataa ctaatttgtt gtccatgctt cgacgcacga cacaagcaca
     1321 agcaagagtc aaggacgatc gatgggaaga tcgggcggag ttcgtcggta ggacgctgtt
     1381 taacaaaaca gttggtgtga ttggtgcagg aaataccgga agcggagtaa tcgaaatttt
     1441 gcgtaacggt tttcgctgtg atgttctagc ttatgatcct tacaaatcag atttatacat
     1501 cgaaagcttt ggtgcaaaaa aagtagaact tcaagaatta ctggaacaat cagatatcat
     1561 ttgtttatgt gcgaatttga cagaagagaa ctatcacatg atttctgata aagaagtcga
     1621 tcagatgaaa gaaaatgttt atctatctaa tagtgcaaga ggcgctctag ttgatgaaga
     1681 agcgatgatt aatggtctga aaagcggaaa gatcgcagga tatgccacag atgttttaga
     1741 agaagaaccg ggacgtcaag atcatccgta tttagcgttt gaacaagtag tgattacgcc
     1801 acatatatcg gcctacacaa gggaatgttt agaagcaatg ggtgaaaaat gtgtcagaga
     1861 tgtcgaacag atcagtcagc accttcttcc tgaacgttct gtccagacaa agagcaacta
     1921 tataaaagga tgatgaagaa aatggtgaac ggtttaaaag tgaaaacagg ccctcaattt
     1981 tatttatatg aagaaggtgg tatttcaaaa gtttctgatc tcttgaaatc atacggcgcg
     2041 aaaagagtac tggtcaccca cggaacggta tcatgggaaa aggcgctacc taaattagta
     2101 tttttgaatg acgaaacgat tcaatttttt tatcatcgtt attctggaga atgtagttat
     2161 gctgaagcca gacgaatagc tacaatcatc aaaaaaatga aatcgatttc gtagttggcg
     2221 ttggcggagg aaaactgacc gatctagtgg gttatagtgc caatcttgca agaatcgatt
     2281 tcggagtcat ccctacttta gctagtaatt gtgctccatg gacacctctt gctgtcatgt
     2341 ataaggagaa tggacaagca gaagggaaaa cagaacactt ttacagacaa gctgcttttt
     2401 ttataacaga tccccaatta gtgattgatt cccctgttcc atatttcatt gccgggttag
     2461 cagatacact agcaaaatgg tatgaatctg agctcatctt agaacaagat tttttgcaag
     2521 atgaatcatt tttgaagcta gcacaagata ctgcgaagat ctgcaaagaa gagattttga
     2581 atcattctgc taaagcaatc caagatatgg cacaaagaaa actgacatcg gagttcaaac
     2641 agctttcaga gattatcttt gctgttgctg gtttagttgg aggattagga gataaatacg
     2701 caagaaatgt ggcagcacat gctatgcatg acgctatcag taaatatatt ccggaaagcc
     2761 atcgttttct acatggagaa aaagtagcgt atgggatttt ctatcaactg gcactagaag
     2821 gtcgctggga aaaaatagac gagttatatc ctttgtatcg ggaattagaa ctgccggttt
     2881 ctctagaaca aatgggatta tttccgaaag ataaacagat aatagataaa atggctgaat
     2941 ttattgattc gaaagagaaa gtgcatttga ttcctataga ggtaacacag aaatcactga
     3001 tacagtcaat gatggaactg gaaggttata tcagaaagat ctgaaggagg aggacacatg
     3061 gaaacattaa gtgtagtaca aagtttgttg attgctttat gggtagccgc ggttatgtcc
     3121 cgctggttag gtggaggagc cacgttgacc ttacgttttt ctcctttgat gactggatta
     3181 gtcgtcgggt tgatcatggg ggaagttgca caagcgatga ttgttacagc cgctttgcaa
     3241 atgatttata tgggggtttt ttctccagga ggatcaatgc cagctgaacc atctattgca
     3301 gcagctatcg cagtaccagt cgcattatta ggggatctgt cgccagaagc agcgattgcc
     3361 gttgcggtgc cagtcggatt gctcggaagt tacttgtatc agtttcgttt tttcatcaat
     3421 acttttttag gtaaatatac agacaaagct gtagaagatt tgaatacaaa agctatggcc
     3481 cgatcaatta ttctttatcc aacggttgcc tcatttttat tattcgttcc gcttgttttc
     3541 attgctttat atttaggggc gccattgatc gctgatgtaa tcaaagcttt agagggaaca
     3601 gtcgttatcc acattcttga agtagtaggt ggagggttag cggcaatcgg tatcgcgaca
     3661 actgtatacg ttatcggtcg aaaagattat ctggtctttt tcttccttgc ttattttatg
     3721 agtgttgttt tgaaatcttt agatattacg atggttactt atgccatttt tgggattatt
     3781 atcgctttga tctttgtcca gtcgcaaaaa gggaaacaag tacagcctgc cacaagcaat
     3841 aacaattcag catcttttga tgacgaagat gactatgatg acggatttta atttaggagg
     3901 aatgggaaat ggctgaaata atggataatc aaacaggtgc tcctgaagaa atcacgaaaa
     3961 aagatgtaac aaaagcctat ctgagatggc attttgcaaa cgaaattcct cactcttttg
     4021 aacgttactt ggcgccatca ctactatacg gaatgatgcc aatcttgaaa aaactttata
     4081 aagatgaaga ctctttaaaa gcagcatata aacggcagtt actgttcttc aacactcaat
     4141 taagctgggg tggcggtgtg attactggcc taatgtcttc tatggaacag caaagagcag
     4201 aagaagagta tgaagaaaaa gagatcttga tgcaggatga cttgatgtat aacacgaaag
     4261 cgggattgat gggggcacta gcaggaatcg gagatgcaat cgattcagga accgtccaat
     4321 atatttttat cgcaatcgcg gtaccttggg cacaacaggg aagtccttta ggcgcacttt
     4381 ttccttttat ctgctttggg ttgtatcagg ttttactagg ggtatttttc gcaagacaag
     4441 ctttcactat gggccgtaat gctacaggcc taaagcaaaa cactggtgtt cagacagcga
     4501 ttgaaatgct atcagtttta gggttgttta tgatgggggt gcttgcggga aactatgtaa
     4561 aagtagaatc ttcattgaaa tttgcgatat ccggacgtga gtttgttatc caggaaattc
     4621 ttgatcaaat cgtgccaggg atattacctt tagctgtcgt aatgggtgtg tacttgttct
     4681 atacgaaaaa aggattgaaa gtcacacaag cattattatg gctgactgga atattaattg
     4741 tgctagcagg aatcggtatt ttataaaaag aagggaacgt gaataagatg ggtgtagtca
     4801 atttagcgcg tgtggatgag cgtttgatcc atgggcaagt aatggtaacg ttatctcaaa
     4861 aaagtggagt gaattccatt tttgttgtag acgaagttgt agcaaaagat aaatttatga
     4921 gagatcttta caaaaatgca ggaagccgta caggacaaaa aacaattgtc attacaccag
     4981 agaaagctaa attctattgg gatgaatatc aatttaaaga atacaattgt attttgatcg
     5041 caaaaacagt ccaaacgatt tacgacttag taaaacacgg aatccccatg gaagaattga
     5101 atattggagg gattgctcaa aaaaatcctg atacagatct tttagtgacg aaatctgttt
     5161 atttaaataa atcagatgct gaaaaattga aagaaatgaa tgaacaatat ggcgtaaaga
     5221 atatttattt tcaagccact ccatctgcac ctaaaacagg attaaaagat gtattgaaca
     5281 agtttgattt gtcataaaca aatgcttaga aaaaagataa agagggcgaa aaaatgaaga
     5341 agaacgagct gtttcgtgat tgggaatttc gttatcgcta tatttaccgt aagcgccgta
     5401 caaaaaagag taaacagcgt tttctttcag cattagtatc agatatttac agtatgagaa
     5461 cagatgtgac agtcattgct tacgatacgc tagcctaccg atcaaaaaat atttatgttg
     5521 gagatatcga aaaagcagag aaagttatct gtacttatta cgatacaccc gttcatgcat
     5581 taggaagtta tttcatgttt gattggaaag accaaaggaa aaaaacaatc tactctatat
     5641 tattgtcctt cattttgttg ttcagtttag gttggtgggg aatgatgata tataacaaaa
     5701 atcctcatca cgtattcgat ctgctatccg tataaacagg tatcactgta ctagcatttg
     5761 ggagctactt tttcttattg ggaaaagcag ctcgcggatg gcctagcaga caaactttta
     5821 ttcgaaatac ttcatccata ttaacgatgc tagaaatgat ccgtacgatt gatgatccga
     5881 gtgtagcgta tgcgtttgtt gatgaaggct gttatggaga aaagggctta gacagcgtga
     5941 gatcgggtat gaaaaaagag gctattcttt tttatctaga ctctgttgag gcagatacac
     6001 cgctacagtt ttcgggaaat tatttttcaa ataaagaaca gtggctgaaa caagttgata
     6061 agttgaaaga aaaaaacgtc aattatattt ttagtgcaag aaaaaagcaa gcgcagttct
     6121 tctatttgac caaaacagat ttacgaggga aaacatttaa ttggcaaaat gccaatcaga
     6181 ttattgctct ttttcgataa gtaaaaagtg caaaacaagg agtgagaaga ctaatgttgg
     6241 aaatcatgat cgttacacat ggtaagttga gcgaaggact gaaagatgcg gcggaagtaa
     6301 ttgtcgggac atcgagccat attgaaacaa tgtgcttaga gtctggggag gacatccaaa
     6361 cattcggaga gaaggtcaaa gaaaaattaa ctatgatcaa cacagcagaa cccatgctag
     6421 tatttgttga tctaattagc gcaagtccgt acaatcaagc gctcttggca gtcaatgaac
     6481 tgactgaaga aaagaaagca gccacttatg tcataggggg cgtgaatctg ccaatgttgt
     6541 tagaagcaat caatcatcag atgcttcaca caccgataga agaagcggtg gaacaaattg
     6601 tcaaacaagg aaaagataat ttaactgttt ggcatgcttc agcggaagaa aaaaaattag
     6661 atgaggacga tttttagaag gaaggctgaa aagatgaagt ggggatttag atggtatggt
     6721 gaaaaagggg attcgatccc attaaaatat gttcgccaaa taccgggaat aaatgggata
     6781 attggaactt tgctgactaa aatgcctgga gatgtttggg agatttcaga aattgaggag
     6841 ttgaaagcat ctgttgagag ccaaggactg gaactgcttg gaattgaaag tgtagcgatc
     6901 cacgatgcaa tcaaggcagg gacagatgaa cgagattact atattgataa ctatatacga
     6961 acaatcaaaa acttgtctcg atgtggggtt cgattgattt gttatagctt caaaccaatt
     7021 tttggatggg cgaaaactga tttgtttaat gaaaacaacg atggaagcta ttctctttta
     7081 tacgatcaga aaatcgtcga tcagatggag ccaggagaaa tgtatcaatt gatacacagc
     7141 cagtcaaagg gattcaaatt gccgggttgg gaagaagaac ggttgaaaaa attcgctcag
     7201 ctggaaaaac tgtatgaagg aatgaccgaa gaagaattat ttgaaaatct gacttatttt
     7261 ttagaaaaag tgattccagt gtgcgaaaaa gcagatgtaa aaatggctat ccatccagat
     7321 gatccgccat gggaactttt tggttttcct agagtgacga aaaatcttgg cgacttgaag
     7381 aaaattctaa atgcagtaga ttctccatat aatggactaa cgctgtgcac aggatcttta
     7441 ggggcaaatc cggaaaacga tttagttgaa atcatccatg aggtaggttc gcgcatccat
     7501 tttgtccact tcagaaacgt ggagttttta ggagaaagaa agttcaaaga aacggcacat
     7561 ccctctacag aaggctccct tgatatgtat catattatga aagcgttggt gcaagaaggg
     7621 ttcgacggtc ctatacgccc tgatcatggt agaaccgtgt ggggtgaagt ggctatgcct
     7681 ggatatggcc tgtatgatcg tgcaatggga ctcacttaca tgcaaggtct atatgaggcg
     7741 ataagtaagg aaaaaccact gggagagcat tatgaataaa atcaagctct tcatctttga
     7801 tatggatggc cttttattag aaactggacg tttagcttat cgtgcttatg taaaatcagc
     7861 acaaaagtat gattatgaaa tgcgtaagga agtctattat ttactaactg gccaaacaga
     7921 aatggcgata agagaacaaa tgggcatttt gtacggagaa gatgttccat atatcaaatg
     7981 gcgagaagca atcaatcaat ataaagaaaa aatcgtgaaa gaagataaga gagtatatac
     8041 gaaaaaagga gcagaagaaa ttttatcttt tgcaaaagaa agaggaatcc atacaatcgt
     8101 ggcttcgtct aatacacggg taaaagtaga aatgtattta aaaatggaaa atctatatgc
     8161 cttgtttgat caaatcattt caggggatga tgtaaaaaaa ggaaagccgg aaccagagat
     8221 ctttttgaaa gcttgttcaa aaatgaatat tcctccaagt gaagcacttg tatttgaaga
     8281 ctcgattgca gggatcgaag cagcaaggcg agcgggcatt ttgtcttttc tcatcaaaga
     8341 tcatttgata gggttgcccg atcataatgg gaagcataag ttgaaagtag atgtaagttt
     8401 atatgaatcc aataaagcag actatgaatt ttatgacctg catcaagcaa aacgattttt
     8461 agaaagtaaa gggttgtatc tctaataaag aggactattt tctagtcctc tttatttatt
     8521 gtcctgcacg actgagggaa cagatgaaaa agaagtaatt ttttattttg aagtatctac
     8581 cttatttgta gtgaacaatt tagaacaaac acaaaacgca tctactgtta tctaccagta
     8641 gatgcgttta aagagaagaa cgagaatcgt ccatatgagg gtttccactc cttatgcaga
     8701 tttttttaat tcttgcactg cttgttcgat cgtaacacct gtcgctacat gattggtatt
     8761 ttctttgtca aaaacgacaa atagattcaa atctgtatcc aaggttactc gatattgtat
     8821 atctttgtta tagaatgtca tagccattct cctttcttta aatacttgct gaaaggcaac
     8881 gaacgcgttg ataacgaaat tccatttata agtataccac caattgaaag gttttcatag
     8941 ttaagaaatt ttaaagtcaa aagttgcaga taaaagcaaa taaacaagaa aacaaaaagt
     9001 gaatcaatcg cggttattca actttttctt cgattcgaag acaatagaag acaatgaatt
     9061 ttatatttca ttgcattatc cttgtgttat tagaaaaagc atgatatatt aaatgagtaa
     9121 tctattttga aacgtaattt gagcgatata tctacataga taaaactcct tttgcctatc
     9181 aaatatttat tgcaacgaaa aaacgtacat tgatacgtat caggaggaat ttatttatga
     9241 ataacggtac agtaaaatgg ttcaacgcag acaaaggttt tggctttatc actggtgaag
     9301 atggaaatga tgtatttgca catttttcag ctatccaagg tgacggcttc aaaactttag
     9361 aagaaggcca agcagtgtct tacgatgttg aagatggtca acgtggccct caagcaacaa
     9421 acattgttaa agcttaataa aaattgactt ttaaccgtct tttcgaaaga aaa
//
LOCUS       DAZKCW010000080         9457 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000080 DAZKCW010000000
VERSION     DAZKCW010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.083"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1206
                     /locus_tag="ACG84Z_002412"
     CDS             <1..1206
                     /locus_tag="ACG84Z_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFP9163216.1"
                     /translation="TLVVDAVLSPTPRACRSCGSTVVDGNGKAIIVKNGKKETIVRFE
                     QYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLSHSIADHVRYKIASLLTEKVSLSF
                     IAKSCQVSLTTVTRTLKEFKSYLPKPSKKILPRVLMVDEFRSHASIEDKMSFICADGE
                     TGNLIAVLPTRKLPRLTSYFLGCTNPEEVEFLVTDMNAAYFQLTKRVLPNAKVVIDRF
                     HIVKHMNQALNELRIREMNELRKAGQKSQAEKLKKNWRFLLKNRASINHYEYKTWKSF
                     RAPKYPFLTEAMMIDRLLEFSAPLKEAYPFFHELVEAFRDKDPDLFFSLLAELPETLD
                     DGFREKLQNLLTYEEGITSAMIYPYSNGKIEAKNTHIKTMKRVSYGFKSFENMRIRIF
                     LINQLINVR"
     gene            complement(1385..1720)
                     /locus_tag="ACG84Z_002413"
     CDS             complement(1385..1720)
                     /locus_tag="ACG84Z_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFP9163217.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(1704..1967)
                     /locus_tag="ACG84Z_002414"
     CDS             complement(1704..1967)
                     /locus_tag="ACG84Z_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFP9163218.1"
                     /translation="MAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQGKI
                     PFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2427..3230)
                     /locus_tag="ACG84Z_002415"
     CDS             complement(2427..3230)
                     /locus_tag="ACG84Z_002415"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFP9163219.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3208..4332)
                     /locus_tag="ACG84Z_002416"
     CDS             complement(3208..4332)
                     /locus_tag="ACG84Z_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163220.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4348..5163)
                     /locus_tag="ACG84Z_002417"
     CDS             complement(4348..5163)
                     /locus_tag="ACG84Z_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9163221.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5153..6025)
                     /locus_tag="ACG84Z_002418"
     CDS             complement(5153..6025)
                     /locus_tag="ACG84Z_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013669610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFP9163222.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6110..7399)
                     /locus_tag="ACG84Z_002419"
     CDS             complement(6110..7399)
                     /locus_tag="ACG84Z_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9163223.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7543..8055)
                     /locus_tag="ACG84Z_002420"
     CDS             complement(7543..8055)
                     /locus_tag="ACG84Z_002420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163224.1"
                     /translation="MTINCDLKEEGLEMAVFSLAQTYQIWPQIVLSGYVQLSWAAIWG
                     KHIFYNIENQFEGKKLGDITEADLIDTLQKLAYQSVQIVNIHEGWLTKLAREVGQQLG
                     LTFSVWTVNELETIEYLARCGVYNITSRCAWAYLWKKGAQNKLFYNQNRGVKRFGDGI
                     HDHMGALFLA"
     gene            complement(8122..8265)
                     /locus_tag="ACG84Z_002421"
     CDS             complement(8122..8265)
                     /locus_tag="ACG84Z_002421"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFP9163225.1"
                     /translation="MITAHSGSDNTEENSWAFLRFCLDRQLCFEVDVRQQTDGTLILA
                     HDR"
     gene            complement(8748..>9457)
                     /locus_tag="ACG84Z_002422"
     CDS             complement(8748..>9457)
                     /locus_tag="ACG84Z_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HFP9163226.1"
                     /translation="LVKQSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSRP
                     KGKKGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNCPLLNQC
                     TISKNHQRVITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKHGMRWT
                     KYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQARVTSLE
                     QLLSTVWLSVRTAFFVG"
BASE COUNT         2904 a         2014 c         1523 g         3016 t
ORIGIN      
        1 acgttggtcg tcgatgctgt tctctcgcct actcctcgtg cttgtagaag ttgtggttct
       61 actgtggtag atggaaacgg gaaagcaatt atagtgaaaa atgggaagaa ggaaacgatt
      121 gtccgttttg aacaatacaa tcatatgcct ttggttacgc gcctaaaaaa gcaacgctat
      181 acctgtaaaa actgtcgtac ccattggacg gctcaaagtt attttgtccg actcagccat
      241 tcaatcgcag atcatgttcg atataaaatt gcttctttac tgactgaaaa agtatctttg
      301 tcttttattg cgaaaagttg tcaggtatct ttgactaccg ttactcgtac attgaaagag
      361 tttaaaagct atttaccaaa gccttctaag aagattctcc ccagagtatt gatggttgat
      421 gaatttcgtt cgcacgcttc catagaagat aaaatgagct ttatttgcgc agatggtgaa
      481 acaggaaact taattgctgt cttgcctacg cgtaaattac ctcgattaac aagctatttc
      541 ttaggctgca ccaatccaga agaagtagaa ttcttagtca cagacatgaa cgccgcttac
      601 ttccagctta ccaaacgtgt tctgccaaat gcgaaagtag tgattgatcg gtttcatatt
      661 gtcaaacaca tgaatcaggc actcaatgag ttgcgtatcc gtgaaatgaa tgagcttcgt
      721 aaagcaggac agaaaagtca ggcagaaaaa ctgaaaaaga actggcgctt tctgctaaaa
      781 aatcgtgcaa gcatcaacca ttatgagtac aaaacatgga aaagtttccg agcaccaaaa
      841 tacccatttc tcactgaagc aatgatgatt gatcgattgc ttgagttttc tgcgcctcta
      901 aaggaggcgt atcccttttt tcatgaatta gtcgaagcct ttcgagacaa agaccctgac
      961 ttatttttct ccttattggc agaacttccc gaaacgttag atgacggctt tcgggagaag
     1021 cttcaaaacc ttctgaccta tgaagaaggt atcaccagcg caatgatcta tccttattcc
     1081 aatggaaaaa ttgaagcgaa gaatacccac ataaagacaa tgaaacgagt atcctacgga
     1141 tttaaatcat tcgagaacat gagaattaga atctttttga tcaatcaatt aatcaatgta
     1201 agataacaaa aaatctgaac cagaatgtgg ttcattctga cccggatttg attttgcaca
     1261 actcatcagt ccttattgac aaagagccaa aaatctgagc cagaatgagg ttcattctga
     1321 cccagatttg attttgtaca acccatcagt ccttattgac aaagagccct tctttttagt
     1381 attattataa ttcttccatg cgttcttcca gtcgctgtaa atcgcttgga cttaattccc
     1441 caattttttt ccatttgacc tttttgttgt ttttgggtaa ttcgtttaga gttcctacgt
     1501 caatccaaga ttcttttttt agtcctgcct gtttccaatc ccttatttca acgtatttca
     1561 gctttatttt atcggattta gtatgatatt ttgaagtaat tgacagaaac gaaattgtgt
     1621 ccagtccatt ttttagaata tagacaggcc ggcgtttacc gccctctgca gctgtgaaag
     1681 caacgtagac ggttgctata tcattagtat tcatcttcat tgaaccattc ttcaattttt
     1741 tcgtcagtgt ctagtttttg gacaggcaat ttttccgcta atctttgaat attatggatt
     1801 cgtttacttt tttccgacaa ttcaatagaa aatgggattt ttccttgctc aacaatttgc
     1861 ttataaaaaa cggtgacggc tgttttgggg ctcatgccta gttcatcaat aatgctttct
     1921 gcttcatttt tcaatttttc gtccatagaa atttgtaact tagccatttt ctccacctct
     1981 ttctgacaaa cacattatat cacggaaaga gttcaaatgg aattaataca actacttttg
     2041 aactccttga aatgcagtgt atttatctaa atataaggaa aggatatagt gctaaatggc
     2101 cttgatagat agaaaagttt caaaatccgc cacagcgata attgaagcga acactcaacg
     2161 acacacagaa caggaaaaga ctcctaaaag aaccaaatta actaggacgt gtctgaaaac
     2221 tccacaaaga tgtggtatgc tctggtaaaa aacgaatggc acaaccacga agaccgatat
     2281 ggttcttgga aaactttctc cacccttttt gtaattggag ggatagtggt ttattgatag
     2341 cgattttcca agttcttcaa gtggaaccag acattgagca ccacggctaa aaagtgaatg
     2401 aagtctttat ttttaatcaa taatttttaa tgattaccag taattggttt tttcatgcgc
     2461 cctatttcta tttgatgtgg agttaaataa tgctgataag taaaaatttt tccgtcaatt
     2521 aaactgccac tagtgaatcc tgttctattg gtaaaaagag aatagtctgg gtattcatct
     2581 acaccaaatg ataaagattc agccataaac tgttttttac cagcaaattc agcactgcta
     2641 ccttgatgga tatgtcctac aaaaatacct aaaatatcac tttcggcaat caattcagca
     2701 aaaccttccg gaacttcagt tacaatagat ggatcttccc acgacaatgg atgatgaacc
     2761 aataaaatcg ttcccttttc agcaggtgta cccaaccact cttgtaattg aatcatctgt
     2821 cctatcgata tttttccttc gtgctgggta tcttgagcag aatccaagga aataattcgt
     2881 aacccatttt gattcgtaca atggatatac tctcccgttt cattgctttc aacactcatt
     2941 ccttcaaaga aaacactgcg acgatcatga ttcccacgac aaaaatagta aggtgtggtt
     3001 gggaaatatt gatccaacat tttccgtaag acttgataat cagaaatccc cccttcatgt
     3061 actaaatcac ctgttaatag aataaaatcg tacactgtta acgagagttc ttgtaacaat
     3121 ttttccaatg ccaactgtgg atttttaatt gttggaaata gttcagcagt aaacaagtta
     3181 gtttgatagt tttctctaaa atggatatca gagagatgca aaaagcgcat ggctattccc
     3241 tctttcttca ataaaataat caggatatcc taaattttct tgcgtctgat aatcaaaaaa
     3301 atgcattctt tcaggttcta tgcggagatt gactgcatca ccaatctgcc aagtaggttt
     3361 ttcattaagg acaatcattt ctataccatc gactttaacg gtgtacgcat aactttgacc
     3421 taatagctca cgatacttca cttgaccgtg taaatcgctt gtttcttttg aaaaggttac
     3481 gtgttctggt cttatgccta aatacaatga gccactaacc tgaagaagtt gtttttgcca
     3541 agctggattc aatgttaaaa attgactggc tacctttaat gttccttgat cataagtaac
     3601 tggcataata ttcatgcctg gcgaaccaat aaaatttgca gtaaaagtat ttttaggttt
     3661 cgtataaaca tttttcggcg tatcaatcat ctgaattcta ccttcattca ataaaacaat
     3721 ccggtcagct aacgtcatcg cttcaatttg atcatgagtg acgtagacaa aagtttgttt
     3781 ataacgttga tgaattttta ccaattcttt tcgtgcatcc aatcgtaaac gcacatccaa
     3841 atttgataac ggttcatcta ataaaaaata attactccgt ttaaccaccg cacgagccaa
     3901 tgctacacgc tgccgttgcc ctcctgacaa atctttagga agtcgatctt ggtatggcgt
     3961 taaacctaac atcttcaaag cttcttccaa acggtgctga atgtcagctg tcttaatttt
     4021 attcgccctt aatgcaaaaa taatattctc ctttacagtc atgtgaggat ataaagcata
     4081 attttgaaaa accattgcga tctctcgttc tccacaaggt agcttatttg ctagttgtgt
     4141 acctaaaaaa agctctccac tcgtaatttt ttccaaacca gcaatcattc tcagcaaagt
     4201 agattttcct gaaccagatg gtcccagtaa cacaattcgt tctccagcgg ccacagctaa
     4261 atcaatttct tttaaaatgg tatgttctcc atattttttt ccgatatttc ttaattcaag
     4321 cgtttctccc atgatttgtc ctccaattta tttaatacct gcagaaacaa aagtcccgat
     4381 aatatatttt tgaaaaattg catacaagac taacggtaca aacattgtaa ttaaactaat
     4441 cgccattgct acggtaaaat ttgtcccacc ttcagaacta atataggtct gcatcgccaa
     4501 cggcaaagta taattatcta ctgtccgtaa aattaatacc ggccaaacat actcattcca
     4561 agaggtaata aaaaaccaaa taccggtaga agtaatcgca tgtctagtaa gaggaaaaac
     4621 aattttactc atgacggttg tttgtttgat gttatccaat gccgccacat ctagaaggct
     4681 cactggaatt tcccgcattg tttgcgtcaa taaaaaaatg cccatcgcat cagcaaattg
     4741 tggtattatc acaccccaag tagtatcaat taaattaagt tttgcaatca acaaataatt
     4801 aggaatcatc gcaacagtaa aaggaatgaa catcgtacca atgatgataa agtaccagat
     4861 tttcttccct ttgattcggc aataagtaaa actatatgcc gcaaaaaaag ctacgcctaa
     4921 cttaacaacc gttataattg tagcaataaa aaaagtattt ctcgtaattt tgataattgg
     4981 aagattttcg aacaaatagc aaaaattttc caaggtaaac ggctgtggta tcaaactagt
     5041 aatcgtctga taggcatctt tcaatggctt aaaagaattg gccataataa acaataatgg
     5101 atagataata atgattatga tgaacataaa taagagatgt ggcaaccagc gtttaatttt
     5161 catagtaaac ccccttttcc acaaatttaa atattacccc taagaaaaca gcaaatatta
     5221 ataaagttaa aactgaaatt gctgaagatt ctccgacttt atacatttca aaagcctttt
     5281 gataagcata atagatcacg tttgcactac cattattcgg tccaccacga gtgatgatct
     5341 taatcggagt aaacacatac tgcagacctt gaacaatggt catcaccaat aaatatagtc
     5401 ctgtcgaact actcataggc aacacaattg taaaaaaaat gcgccagatg ggtacacgat
     5461 ccaacttagc tgcttcgatc atctcttgat caattcccac aattgctgca aaaatgacaa
     5521 tgaaattata accaaaaact ttccaagcag taatacctgc aatcacagca attacccaac
     5581 cttgtaaatt catccacata ggcagtctta aaccaaaatt tcccaacaag acagcaattg
     5641 gtcccgatac cggatttaat atccatgtaa aaaccatccc cgccactacc aaagaaatca
     5701 cagctggaat aaaaaataat ggtttataca aattctgccc tttttctata actattccta
     5761 ataaaaagga tgtaatatat gggaacacac agctcagcaa gacaaataga acggtatagg
     5821 acaaagtatt cttcaacact ttatgaaaga ctggatcagt cagcaccttt acatagttgg
     5881 caaagccaac aaattcttta gtgggggcca ccatattcca gtcaaaaaaa ctcaaataga
     5941 tcgtataaat caatggataa aaaacaaaca cgcccaacaa aataattgct ggcgccagat
     6001 acaaataacc tacatagcgc ttcatttccg acagcctcct catccttatg tcaaaagcag
     6061 acgaccttgt ttttcctttc ttacaggcgc tgtcgtctgc ttgctttgct tatttgagta
     6121 actcattaat ttccttttga gtagctttca tcgtttcatt gacggaatta cctgataaaa
     6181 ttttatcccg catatccaac aatttttgtt cagcttctaa tccagcatct ccaggaaatg
     6241 aactccaact gaccatctta tccatctgat caattgctgg tatcatcatc tgattttcag
     6301 ctaagaaagc ttttaatcca ttttgggcgt ctgcaacatc tttacgtggt ggtaaataac
     6361 cagtaccttc tgtccattta gctaaagatt caacactata aagatatttt aagaaatccc
     6421 aagttgcttc ctttttctta tccgtttgtg atgtaacagc taacattgcg ccaccagcag
     6481 gtagtttaac ttttttccct tcccaacttg gtgactcaac tgctttagca gtaaaagtac
     6541 tatttttttg aatgttgtcc ctttgagcaa tagtggtata gaccatcgcg acgttaccat
     6601 caataaagct ttgcacacct tgttcccacg tagtgtgtaa tgccgtctgg tcttttacca
     6661 tcctttgata taattcataa gcagcgatac catctttaga agcaaaggta gctttgccat
     6721 cttttattac acttgcccca ttactttcta aaattgcttg ttgtgcccaa ttatcagcag
     6781 gttcttgaat atacacgcca tactttccag ttttttcttt tattatctta gaaaaagttt
     6841 gaacttcttc ccaagttttt ggaccatttt catccaagcc cgctgctttt aatatatctt
     6901 gatttaaata taaaaccgga ttactaatgg agtaaggaat acccacttgt ttaccatctt
     6961 tttcagacag tgccatgata ttgtctaaaa aatgatcttt aaaataatca gcattatccg
     7021 gatccacttc ttctactaaa gattgaggat tagtatattt gaaattttct gcaaaataat
     7081 ctttaaaagc ccatcccact tgtactacgt ccggtatttc tttggaggca acagaagctt
     7141 gtaaattttg catcaagcct ttatacatat caggattata ttttgctaca accttcactt
     7201 tgtcttgaga ttgattgtat ttatctacta attcattcac tgtttttcca cctagggtat
     7261 ccgcattaac atgccaatac tctatcgtta cacgaccctc cgattttttt gttgtcttgg
     7321 tattcccact accacaagct gccaaagaga tgacacttaa aacagacaca acccctataa
     7381 caagattttt ctttaacata acattaactt cctcctaatt tctttatggc catttttcta
     7441 atcaagaaat attatgaact accaatgtaa atttctagtt aattttctgt aaataattcg
     7501 aaatttgtgc atttcggggt acagggtcac tggacatatc catcaagcta agaataaagc
     7561 ccccatatgg tcatgtatcc catctccaaa tctcttaact cctctgtttt gattataaaa
     7621 tagtttattc tgtgctcctt tcttccataa ataggcccat gcacaacgtg aggttatatt
     7681 ataaacacca cagcgcgcaa ggtactcaat cgtttctagt tcattgactg tccatacaga
     7741 aaatgtcaat cctagctgct gccccacttc acgggccaac ttagttaacc atccttcatg
     7801 aatattgacg atttgaacgc tttgataggc taatttctgt aaggtatcga tcaaatctgc
     7861 ttcggtaata tccccaagtt ttttcccttc gaactgattt tcaatattat aaaatatatg
     7921 ctttccccaa atcgcagccc aagataattg tacatagcca ctaagaacaa tttgtggcca
     7981 gatttgatag gtttgtgcca gcgaaaaaac ggccatttcc aatccctctt cttttaaatc
     8041 acagttaatg gtcatggttg ccttctcatt ggccactgct tgaaacacct gctcaagggt
     8101 taccgaatct gggacaactt cttacctgtc atgggctagt attagcgtac catctgtttg
     8161 ctgacgcaca tctacttcaa aacaaagctg gcgatccaaa caaaagcgaa gaaatgccca
     8221 gctattctcc tccgtattgt cactaccaga gtgtgcagtg atcatggtca ttttgacccc
     8281 tcctttaatt ccgtgatttt ctcccacacg tccactatac cgatgaagcg ttaatttctt
     8341 gttaatttct tgtaaattcc ctgcgttttt tcagtaaact agttgtaaat cttgcatgct
     8401 ccttcctacg aactcatgaa tcgtcgattt tgcccttcta gctagtttca ccaattaagt
     8461 agttctacat tccccgcttt taacctacta cacctttttt tgttttcagc tattccttct
     8521 tcttgctgaa agtccttgag gttctttctt acaggatacc atcaaggtgt tcaatggctt
     8581 attcccattg aatgaccgag acttactatc agatttctgc tcgttgaacc aagtctttga
     8641 tacaggattt cttccgtcat cttctcacaa ataccacctt gcgtttctct agcgattggt
     8701 cgatgtgcac cctcccagtg gactgtcact accccttttt gctatgccta gcccacaaaa
     8761 aaagctgtcc tcacagacag ccagactgta gacaaaagct gttccaaact cgtaactcga
     8821 gcttggaaca gctttttatc tacttcgttt cgaatttttg aacaaaaaaa taaaggctcc
     8881 ttgcctttcc atagccaggt ggctaatttc tttaaattca ttgcagcaaa cactagcatc
     8941 gtatgcgtcg cgactttttc caagcctcga tacttggtcc aacgcatccc atgcttttct
     9001 tttgcatccg caaatattcg ttcaatcgtt tgtttccgtt ttttgtaaat tgatttattc
     9061 agatctgtta ggcgaagatg ttccacttca tccatcagat ctccccaaac atgtctcgtg
     9121 atgactcgtt gatgattttt acttatggta cattggttta gcagaggaca gttcacacat
     9181 tcttttggat tggatttgta ttctcggtac ccttctcgag taaccgttga aaaagcgagc
     9241 atttgatctt gcggacaaat ataacaatca aaatactcgt catagagaaa ctcatttttt
     9301 gataatagcc cctttttccc tttgggcctt gaataaggca aacaaggtcg aaggttcaaa
     9361 tgagtcaaaa agtgaacaaa cttaggtgtc ttatacccag catcagcgac aacacaattg
     9421 atttcaggaa aaagtctctt cgattgtttg acgagct
//
LOCUS       DAZKCW010000081         9297 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000081 DAZKCW010000000
VERSION     DAZKCW010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.084"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(78..2198)
                     /locus_tag="ACG84Z_002423"
     CDS             complement(78..2198)
                     /locus_tag="ACG84Z_002423"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFP9163227.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="ACG84Z_002424"
     CDS             2428..3606
                     /locus_tag="ACG84Z_002424"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFP9163228.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="ACG84Z_002425"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="ACG84Z_002425"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFP9163229.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="ACG84Z_002426"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="ACG84Z_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFP9163230.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="ACG84Z_002427"
     CDS             complement(4959..6212)
                     /locus_tag="ACG84Z_002427"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFP9163231.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="ACG84Z_002428"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="ACG84Z_002428"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFP9163232.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="ACG84Z_002429"
     CDS             7789..9135
                     /locus_tag="ACG84Z_002429"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFP9163233.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
BASE COUNT         2995 a         1680 c         1925 g         2697 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatc
//
LOCUS       DAZKCW010000082         9283 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000082 DAZKCW010000000
VERSION     DAZKCW010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.085"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(14..682)
                     /locus_tag="ACG84Z_002430"
     CDS             complement(14..682)
                     /locus_tag="ACG84Z_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFP9163234.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            816..1103
                     /locus_tag="ACG84Z_002431"
     CDS             816..1103
                     /locus_tag="ACG84Z_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163235.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1519..3057
                     /locus_tag="ACG84Z_002432"
     CDS             1519..3057
                     /locus_tag="ACG84Z_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFP9163236.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3054..4019
                     /locus_tag="ACG84Z_002433"
     CDS             3054..4019
                     /locus_tag="ACG84Z_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163237.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4006..5328
                     /locus_tag="ACG84Z_002434"
     CDS             4006..5328
                     /locus_tag="ACG84Z_002434"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFP9163238.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5391..5495
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5569..6312
                     /locus_tag="ACG84Z_002435"
     CDS             5569..6312
                     /locus_tag="ACG84Z_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9163239.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6327..7319
                     /locus_tag="ACG84Z_002436"
     CDS             6327..7319
                     /locus_tag="ACG84Z_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFP9163240.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVNYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7331..8068
                     /locus_tag="ACG84Z_002437"
     CDS             7331..8068
                     /locus_tag="ACG84Z_002437"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163241.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8058..8780
                     /locus_tag="ACG84Z_002438"
     CDS             8058..8780
                     /locus_tag="ACG84Z_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFP9163242.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8864..>9283)
                     /locus_tag="ACG84Z_002439"
     CDS             complement(8864..>9283)
                     /locus_tag="ACG84Z_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFP9163243.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3039 a         1603 c         1962 g         2679 t
ORIGIN      
        1 tgaaaaataa gaatcagtgc tctaactgtt caagaggatc aagtggttca aatgtttctg
       61 tagtctgttt tgcttccaat tggggcaaaa cagatccaat ttccagatac ttcactttat
      121 tcaatgtata agatagaata gaacagctaa gtaatgtata cagaaaatgt gtgagatcca
      181 aataaagcaa ggagacaact aaaataccaa aagtaatcaa gaaaagactt ttgccaatct
      241 taatatgaaa atatttttca atggcttgat aaatgatatc tgttccgcct gtgcttccgc
      301 cgaatcgaaa gacgagaccg caaccaatgc cagaaagaat acctgtcatc aaactattga
      361 tcagtagact atctacagca aaatgtatat gaaggctctc ccataaatgt aaaaagaaaa
      421 ctagcgcaaa tgttccgacg atcgtccgga gaaaagcgtg ttttccaaaa agaaacaatg
      481 agataagcaa taaaggtaaa ttaaaaagca gtgaagtgac agaaggagcg aatccaaaaa
      541 gattatgcaa aagcaaagca ataccagtaa ccccaccatc tgccagctta gatggaatat
      601 tgattcctgt cacagctaat ccgtagattc ctgcgcctaa aatgattccg cacaattctg
      661 taaataaatt taattttttc atttctagcc tcttttcttt tgaaaatttt cagcaacttc
      721 tttattatac tgacttatac tcttacttca agaggaaaat gaaaaaaaat tatttttggc
      781 tgtttctttt tatttatcaa ataaggagtg gaaaaatgcg agcagcagac ttattgacaa
      841 ttcttacaaa atcacccaaa aaaacagagt atcaaggagt ttttttggct caagaacaaa
      901 aactggtgcc tgtgacaatg gtccagataa ataaagcaaa tcaatttatc tttttatttg
      961 aacacggcaa agcaccactt gctatgaaag acatctttct ttttttgatg aagaaccgtg
     1021 agaaagctgt ttattatcag tcaaaagaag aactcattcc tctttatgga gtgaaagaga
     1081 tagaaaataa agtggtgata taagtaaaaa taagaaaaca agacgtttat gatgtcaaaa
     1141 caaccatttt ttacattttt ggcaaaaaag tgtcatgata cagtataata ttcgttgaac
     1201 aggccaataa aggtgttctc ccccacgaga tttctacttt attggctgtt tctttttatt
     1261 aaaataaaag ttgtgtgtgt aaaaaagata tagctgattc caagtgacaa tttcgtatag
     1321 atttttatgg tattcgtagt gaaaaaacga gaaccaaaaa gttgatccga ctttgttgct
     1381 tggattcttt ttttgtcagc atatttagag gtattttttt cttttttttg ttcgtgctgt
     1441 aaggttaagg caagacaagt tagttgggaa aaaggaaaga aatgtttata cttaaagaat
     1501 aacagaaagg aaggtcgcat gaataatttt atacaaacat taagtgaaag aaaaggcgag
     1561 ttgctggaag ctgcatttca acatctgtcc atttctctca tttctttgct gattgcagca
     1621 ctgattgcta ttcctttagc gatttgggca gccaatcata aaaaaatggc agaagtctta
     1681 ttgcagatca cgggtgtgct ccaaacgatt ccttcacttg ccttattagg tttacttatc
     1741 ccatttgtag ggatcggaac tgttccagca ttgattgcac ttgttattta cgctttgctt
     1801 ccgattttcc aaaacacgta tattggtcta gctgaaattg acccgtctat tgaagaagca
     1861 gcggtagcat ttggtatgtc cagaatgaga cgcttgctga aagtagagct tcccatcgca
     1921 ttacctgtca ttatctcagg tatccgaact gccttagttt taatcatcgg tacggctact
     1981 ttggcagcat tgatcggagc aggtggatta gggacattta ttttgttagg tattgaccga
     2041 aatacacctg ttttgacatt gattggtgcg atcagttctg ccttgcttgc aattatattc
     2101 agcggactga ttcgctggtt gcagcataag aaacctcgat attccatcat tactttagca
     2161 gcagtggtgt gtttatttgg cggcgtttct ttatatcagt ctgccttgtt taaaaatgaa
     2221 accatcacga ttgctggaaa attaggagcg gaacctgaaa tcctgatcca aatgtataaa
     2281 gaattgattg aagacaacac aaaaacagaa gttgaattaa aaccgaattt tggcaagacg
     2341 agttttttgt tcaatgcact ggatcaaggt caaatcgata tctatcctga gttcacaggt
     2401 actgtcctag aaagcttggt gaaggtacct gaagcaatga aaagtgctga tttgacaaaa
     2461 gaaaaaacat atgacgaagc agaagaatta ttgaataagc aattcgatat gacattatta
     2521 aaaccaatgg cttaccaaaa tacgtatgcc ttggcagtca agagatcttt tgcgaacgaa
     2581 catcaactta aaaagatttc cgatttggca gctatctctg atcagatcaa agcgggattc
     2641 acactggaat ttattgatcg ttcagatgga tataaaggaa tccaagaagc atatggcttg
     2701 aatttttcaa gtgtacaaag catggagcca agtttgcgtt accaagcaat caataatgga
     2761 gatgtcaata ttgtggatgc ctattccaca gatagccagc tcaaggagta cgatctagtg
     2821 actctagaag atgatcgagg gttattccca gcttatcaag gcgcaccgct gatgaaaaaa
     2881 gattttgcta aagaacatcc tgaaatcgtt aaagcactga ataaattaag cggaaaaata
     2941 acagaggatc aaatgattga tatgaattac caagtcaatg tcgaaaagaa aaagccgaca
     3001 gaagtagcac gaatcttcct gaaaaatgaa ggattagtaa aggaggaaga tcagtgacta
     3061 aattaatcga gttcaaacat gtgcaaaaaa agtatgatgg aaagtatgtc atcgatgacc
     3121 taaatctggc aatcaaaaaa ggagaaatct ttgttttggt tggtccttcc ggtagtggaa
     3181 aaacaactac tttgaaaatg atcaatggat tatctaaacc atcagcagga gacatctact
     3241 tcaaaggaaa atcgttaaat gaatataatc tgcagaaaat gcggtggaat atgggatatg
     3301 tgctgcagca aatcgctttg ttcccgacca tgacagtcaa gcaaaatatt gaagtcatcc
     3361 ctgaaatgtt aggttgggaa aagcagaaaa gagcagaccg tgtagatgaa cttcttcaaa
     3421 aagttggctt atctcctgat atttatcgag atcgtatgcc tagagagttg tctggaggag
     3481 aacagcaacg gatcgggatc atccgagcta ttgctgcaag cccagatgtg attttgatgg
     3541 acgagccatt tagcgcatta gatccgattt caagaaactc attacaagaa ttggttttgt
     3601 ccttacacga agaattgggc acgaccatcg ttttcgttac gcacaatatg gaagaagcaa
     3661 tcaagctagg tgatcgtatt gcatttatga aggatggaga aattatccaa tgtgacacac
     3721 cagagcagtt attgatgaat cctaaaaacg actacgttcg gcatttcttt gatgaaccga
     3781 aacagacgaa agagtggcga gtagaagatt tagtcgtcaa tggatatttc ttaaatgaaa
     3841 taccagaaaa tgctcgtcaa caagtttgct ttgatacgcc tatgaaagaa gtatattcgc
     3901 ttctttcggt gtatccaagc attgtgatag tagaaaagca aagaagtatt gggtcgctga
     3961 caagtaaaga aatctttgct tttttaagtc gagaggagga aggaaatgaa aacatatgat
     4021 gcaatcatca tcggttcagg tgtgagcggc ttaagtgctg cttatggatt gaaagaagca
     4081 ggtaaaacag tactagtggt cgaagaagat ctatggggcg ggacttgtcc taaccgtgga
     4141 tgtgatccta aaaaagtctt gttaagtgca gtagaggcac gtaatcgggt aaaacaattg
     4201 agtggaaaag gttttaacga gatcccaact gccaactggg aagaacttca aaaattcaaa
     4261 cgaacattta cggatccagt cccagaaagc cgaaaaaaac aattagcaga agctgaaatc
     4321 gatcatcttt caggaaccgc tcgttttttg gatgattcat ctattgaagt caacgaagaa
     4381 gtcttccatg cggattactt agttttggca accgggcaaa gacctacgat cttaccagtg
     4441 gagggaaagg aatacttgaa aactagtgca gactttttat cattgcctgt actgcctaaa
     4501 gaaatcattt ttatcggtgg tggttatatt gcttttgagc tagctacgat tgccaatgct
     4561 gcagggagca aagtaaccat tgtccatcat aatcaacggc cattaaaaga atttgaggcg
     4621 tctttggtag aggaagccgt ccatcaaatg gaagcatctg gcattcagtt tgcttttggt
     4681 gttgaaaccc aaaagatcat ttcagaaggt actcgctatc gtttagtcgg aaaagagacg
     4741 gaattagtag cagatatgat tttttgtgcg actgggagac agccgaatac agaatcttta
     4801 gcacttgagc aagcgaatat cgtctttgat aaacacggaa ttgcagtcaa tgattatctg
     4861 caaacgagca atccaaaaat ttttgcgtgt ggagatattg tttcaaggaa aaccccaaaa
     4921 ttgacaccag tcgccacttt tgaaggaaat tatgtagcta agcggataac ggatgcaaca
     4981 agcgaaccta tcaaatatcc gattatacct acgatcgtct acgccagtcc taaacttgct
     5041 gaagtaggag ttacaaaaag tcacgcctct tcgtcagatc aagtggtaga gatggatctt
     5101 accagttggt tcacctatca tcgtgtcaat gaaccagttg ctaaggctga attgaccttt
     5161 gaccagcaaa attatttgat tggtgctgca gtgattagcg agcaagcaga cgaattgatc
     5221 gatgatttga cactcgtcat caatcaaaaa ttgactaaaa aagagttgga tagctatatc
     5281 atggggtatc cgacattggc aagtgatctc tcctatttat tgaaataatc agcatgataa
     5341 ctaaagcgct tgttgctttt tccttcttgt gctacacttt aaaaaatgaa tacctgtttc
     5401 tggggatgtc gtagacgaca tgagagtaag ttgtgaactt agacccattg aacctgtcag
     5461 ttaatactgg tgaagggaga aacatagcag acgcttgaag cgggttacta tgtcgtgccc
     5521 atttcaagcg ttttttgtta ttcatattag aagaaaggag gtaacaaaat gaagaaaaat
     5581 ctttatccag cagtcagtat ggcattcatt ttaattattt ggcagattgt tgtcatagtt
     5641 tggaaaatac ctgcctttat tttacccgga cctgctgctg tattttctgc attagcggca
     5701 gatgcacaag tattactttc ccattctgtc acgacattaa atgaagcagt gcttggtttg
     5761 gtaatagcta gcgttctttc ttttattact gccttggcaa tggattattg gaagttttta
     5821 gaaatgtctt tttatccgtt actagtgatt tcacaaatgt tgccaatcat ggtgttaggg
     5881 ccattactta ccctatggtt tggtttcggt atgcttccaa aagtgatcct tgttgtcttg
     5941 ataagctatt ttccgatcgt agtttctttt tcggatacat tgaggaaagt atcaaaagag
     6001 caaatcatct ttttgaaaac gatgggggca gatacaggga agatttatcg aatatataaa
     6061 ataccagcgg gtttatccgg cttcttttcc ggtttaaaag tggctgctac ttattgtgtc
     6121 agcggagcag tcgttggaga atggctaagc gctcaagcag gcttagggta ttacatgata
     6181 cgcgtaaaaa acagctacca gatcgataaa gtttttgctg cgatcatttg tgtcattcta
     6241 ttgagtttat tgctgaatgg cgcttgttca ttattgaaaa aagggtatta tcgtatgctt
     6301 tatatttttt aagagaaggg gatcaaatga aaaaattatg gcttttatta ccgctactgt
     6361 tgcttttatc cgcttgtggc actgcaaaag aaacaagtag caaacaagaa ataaaggatt
     6421 tgaaaaaagt gacacttgtt ttggattatg taccgaatac taatcatact ggcatctacc
     6481 tagcaaaaga aaaaggctat tataaagagg ctggtttaaa tgtccaaatc atcgaaccag
     6541 gagataattc gacaagtatt ggtctagtag gtgcggacaa agcacaattt ggtgtaaatt
     6601 atcaagaaga tgtcacttat gctcacgcag atggacagaa tataccagtc aaagcaattg
     6661 ctacagtgat caaacataat acttctggat tcgccaccct atcagacagt aacatccatt
     6721 caccaaaaga ttttgaagga aaaacatatg caggttggca aagtccaagt gaagaagctg
     6781 tcttaaaagc tgtgatggaa aaagacggcg gggacttttc aaaactgaca atggtaggaa
     6841 gcaatggaga agggccagaa agcttaggaa aatcctcaga tatccaatgg tactttgaag
     6901 gttgggatat gatcaaagca aaagaagcgg gtattgaact aaactatatc ccattgaaag
     6961 aattagatga acggttagat tactatactc cggtaattat tacgaatgat caactgatca
     7021 aaagtgatcc agaattggta cagtctttta tggatgccac gaaaaaaggc tatcaggaag
     7081 ctattaagga tccaaatgac agtgctaaac tgttgcaaaa atatgcaaaa gaaaatgatc
     7141 ggacgttttt agaagaatca caagcattct tgtcaaaaaa ttatacggat gatcctgaga
     7201 attggggatt gatggaagaa aaagtttggc gcaattatac agcttttatg caggaaaacg
     7261 gattgatcaa gcaagatgta ccttcgcaag aactattcac taatcagttt ataaaatagg
     7321 agtgatagat atgtcaatcc aaatcagcca cttgaatgta gtcattgaaa acctgaaaat
     7381 attagaagac atccatttca ctatccctaa agataccttt acatcgattg tcgcgccaag
     7441 cggagccggt aagtcaacat tgctgaaaac tttaacagga gtccagccta tgacttctgg
     7501 aacgatcaaa gtagacgatc aaaaagtaac tggtctccat acagcattta gttatatgcc
     7561 gcaagaagat atgttacttc cttggctgag cgtctatcaa aacgttacgt tatatcaaaa
     7621 aatcaatcat ctaacaatca atgaagaaca agtaagggat tatctggata tctttgggtt
     7681 aaacggctat gaacattttt tgccggaaca attatctggc gggatgaagc agcgaacggc
     7741 cttgttacga acaatcatga atccttcttc ttacttgctt cttgatgaac catttggagc
     7801 gttagatgct atgaccagag ggcagatgca agactggatg ttgaagctgc ctaaaaaagc
     7861 aaagcggact actttacttg tgacgcatga tatcgaagaa gcaatttatt tatcagacag
     7921 gattcttgtg ctttccgccc gtccggcaca tgtgattgct gagattcaag tgcctgaaaa
     7981 acgacggtca cgtgaatggc tactgcagca atcagagttg aagcaaacga tttatcagtt
     8041 attggcaggt gaattagatg ttaagtgatg ctcattgtca tttagatggg agtcagagtt
     8101 tagcactcct tcagcaggaa cacacgattt tgacgatcat caattgtgat tcgccagaag
     8161 aatggaagga aaacagacag cttgcagcaa gtaagactca agccttaagt tacggtatcc
     8221 atccttggaa agcagatagc tatacgtttg aacaagttga gccttttttg aaaaaagcaa
     8281 ggatcatcgg tgaaataggg ttagataata tttggacgaa tgtaccgatg actacacaaa
     8341 aaaaagtatt tgagcgacag cttgcttttg cagccataaa tgagaaacct gttgtactgc
     8401 acacaaaagg atgcgaaaaa gagatcttaa attatatcca agcttaccct aatcactatt
     8461 tgatccattg gtattcttct ttggactatc aacaagacta tattgattta ggctgttatt
     8521 tcagcattgg tcttgatttg aaaaagaatc cagcagtctg gcaactagct aaagcagtcc
     8581 caatcgacca cttacttatt gaaacggatg gactacatgc agcagagtgg gctttagggg
     8641 ggattttttc agaaaaagat tatgtctcac tgcttgaaga acagttaaag acaatcgctg
     8701 agatcaaaga gctatcagtt gaagaagtta aaaaaaatac ttatcaaaac ttggaacgtt
     8761 tcattagatt aggtaaataa aaaagagatg tgacacaact agtgtcgcac ctctttttgg
     8821 ctttctttgt ataaaagtaa actgtttgat taataaatga atcttagtac caaccgtttg
     8881 cttcccagaa tgctttcgcc gcttcccaag aaccataacg tgaagtaaca tattgttctg
     8941 ctactctttc ttggtttgca gcagagtagt caccatttaa gtaagaagaa tctaattggt
     9001 aacgtccgat gtaacgtccg ttcgttgctg tgtaagaacc gcttgattct ttttgtgcga
     9061 tccattcttt tgcagagctt gtgcttgctg gagtagcagc agtttctgtt acagcaggag
     9121 caggttgtgt ttcagcaaca ggcgctgctt gtttttccgt ttgaaccgtt tcttgtacaa
     9181 caggttgttc agcttggact ggtgcttctt gaacggctgc ttgaggttca gcagctgctt
     9241 gtgcagagcc ttctgttggg attgttaatt gttgtcctga gta
//
LOCUS       DAZKCW010000083         9016 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000083 DAZKCW010000000
VERSION     DAZKCW010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.086"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            71..154
                     /locus_tag="ACG84Z_002440"
     CDS             71..154
                     /locus_tag="ACG84Z_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFP9163244.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            279..1016
                     /gene="erm(B)"
                     /locus_tag="ACG84Z_002441"
     CDS             279..1016
                     /gene="erm(B)"
                     /locus_tag="ACG84Z_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFP9163245.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1186..1446
                     /locus_tag="ACG84Z_002442"
                     /pseudo
     CDS             1186..1446
                     /locus_tag="ACG84Z_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1609..2274
                     /locus_tag="ACG84Z_002443"
                     /pseudo
     CDS             1609..2274
                     /locus_tag="ACG84Z_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2310..2555
                     /locus_tag="ACG84Z_002444"
     CDS             2310..2555
                     /locus_tag="ACG84Z_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFP9163246.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2658..3527
                     /locus_tag="ACG84Z_002445"
     CDS             2658..3527
                     /locus_tag="ACG84Z_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFP9163247.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLLECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3508..4242
                     /locus_tag="ACG84Z_002446"
     CDS             3508..4242
                     /locus_tag="ACG84Z_002446"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9163248.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4275..5183
                     /locus_tag="ACG84Z_002447"
     CDS             4275..5183
                     /locus_tag="ACG84Z_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFP9163249.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5180..5722
                     /gene="sat4"
                     /locus_tag="ACG84Z_002448"
     CDS             5180..5722
                     /gene="sat4"
                     /locus_tag="ACG84Z_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFP9163250.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5815..6609
                     /locus_tag="ACG84Z_002449"
                     /note="aph(3')-IIIa"
     CDS             5815..6609
                     /locus_tag="ACG84Z_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFP9163251.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            6885..7016
                     /locus_tag="ACG84Z_002450"
                     /pseudo
     CDS             6885..7016
                     /locus_tag="ACG84Z_002450"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            7092..7837
                     /locus_tag="ACG84Z_002451"
                     /pseudo
     CDS             7092..7837
                     /locus_tag="ACG84Z_002451"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7948..8127
                     /locus_tag="ACG84Z_002452"
                     /pseudo
     CDS             7948..8127
                     /locus_tag="ACG84Z_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636358.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibD"
     gene            8230..>9016
                     /locus_tag="ACG84Z_002453"
     CDS             8230..>9016
                     /locus_tag="ACG84Z_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HFP9163252.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNI"
BASE COUNT         3162 a         1401 c         1873 g         2580 t
ORIGIN      
        1 ttttgtgtat aataggaatt gaagttaaat tagatgctaa aaatttgtaa ttaagaagga
       61 gggattcgtc atgttggtat tccaaatgcg taatgtagat aaaacatcta ctgttttgaa
      121 acagactaaa aacagtgatt acgcagataa ataaatacgt tagattaatt cctaccagtg
      181 actaatctta tgacttttta aacagataac taaaattaca aacaaatcgt ttaacttctg
      241 tatttattta cagatgtaat cacttcagga gtgattacat gaacaaaaat ataaaatatt
      301 ctcaaaactt tttaacgagt gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa
      361 aagaaaccga taccgtttac gaaattggaa caggtaaagg gcatttaacg acgaaactgg
      421 ctaaaataag taaacaggta acgtctattg aattagacag tcatctattc aacttatcgt
      481 cagaaaaatt aaaactgaac actcgtgtca ctttaattca ccaagatatt ctacagtttc
      541 aattccctaa caaacagagg tataaaattg ttgggagtat tccttaccat ttaagcacac
      601 aaattattaa aaaagtggtt tttgaaagcc atgcgtctga catctatctg attgttgaag
      661 aaggattcta caagcgtacc ttggatattc accgaacact agggttgctc ttgcacactc
      721 aagtctcgat tcagcaattg cttaagctgc cagcggaatg ctttcatcct aaaccaaaag
      781 taaacagtgt cttaataaaa cttacccgcc ataccacaga tgttccagat aaatattgga
      841 agctatatac gtactttgtt tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta
      901 aaaatcagtt tcatcaagca atgaaacacg ccaaagtaaa caatttaagt accgttactt
      961 atgagcaagt attgtctatt tttaatagtt atctattatt taacgggagg aaataattct
     1021 atgagtcgct tttttaaatt tggaaagtta cacgttacta aagggaatgg agataaatta
     1081 ttagatatac tactgacagc ttccaagaag ctaaagaggt ccctagcgcc tacggggaat
     1141 ttgtatcgat aaggggtaca aattcccact aagcgctcgg gaccccttgt aggaaaatgt
     1201 cctaagtgtg gcaacaatat tgtattaaaa aaatcgtttt atggttgttc aaattatcct
     1261 gaatgtaagt ttactttagc tgaacatttt agaaagaaaa aactaaccaa aacgaatgta
     1321 aaagaattac tggagggaaa agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag
     1381 ccctacaatg ccgttgtaaa aattggggaa aagggatata ttgattttat ctctttttca
     1441 aaataaacat ggggctgacc caaaagtagc tcctatatga aaaatagagg tctttccatt
     1501 tagatagtag tggaaagacc tctatttatc ttttgaaagt gaatacaaaa ataaagcaca
     1561 ctctgctata atataggtga ttaatccatt tgagagaggt gctttatcat gtatcaaaat
     1621 tataccataa accaactttg tttgcctata gatcttgaaa ttaaattaga agaaaatgat
     1681 tttgctcatg ccattgtgca gtttgttgac tctattcccg atgaagtctt tcttccttat
     1741 tatcaatcta tgggtagacc ccaatatcat cctcgtatgc tactttccat tattctttgt
     1801 gcctatattc aaggggttta ttcgggccgc caaatacaaa atatgctgat agatagtatt
     1861 cggatgcgct acttatctca agagcaattc cctaactttc gtactattaa tcgttttcgc
     1921 gttcatccga ttatgaacga tattctagat cattcatttg ttcaatttcg tgagctactg
     1981 gttcaaagtg gcttaatcag tggcagtgct ctatacattg atggtacaaa aattgaagcg
     2041 gatgcgaata aatactcttt cgtttggaaa aaaagtattt taaagtataa ggatagcctt
     2101 gatcaaaaag cccttgaaaa ctaccaacaa atggtggaaa caaaaatctt acctgagtta
     2161 atagatgatt taaaggatga actttctata gaagagattg aaaggattcg tcaatctttg
     2221 gaagaaaagg aaaatcaatt aattgaagcg attgaccaaa ccgaaacagt agaagggggc
     2281 tgacccatta ttaataagga gtggacaaca tgattgatgt aaatgagcta ttggaagaag
     2341 ctattagaga aactgaaaat ctaaatgatg gcgaagtttt tcttgttaaa gatttattca
     2401 agggatatgt ggggaatagg atacccagaa aggatcgact tctgcttgga acgttatttt
     2461 taaaccatgt tagcaaaatg aatggtaatt taaaggctat tgaaaagact tcatctaatc
     2521 agcagaggta taaaaagaca attgataagt tttaactatc ttttgtgaaa ttaaaaaaat
     2581 tataaatatg ttgagtagaa gcaaaagatt tggcttggaa tttttacagc agtgaatcga
     2641 taaaaggagc atgcttgatg gtagataata ttattaaatc agtagcagag aaattatcct
     2701 ctctgtctta tatagaaggt attgttttag gtggttcacg tgcaaggggc acccatacag
     2761 aggattcgga tatagatatc ggcatctatt acaattcaga atcatttgac ataaatacta
     2821 ttaatcaatt cgctacaaag ctggatgatg agcatagaaa taaccttgtt gtacctcccg
     2881 gagcatgggg tgattggatt aatggcggcg gatggttagt cataaacggg tatcatgtgg
     2941 atttaatttt acgtgatatt aaacgtgtgg aacaaataat gaaagataca gagcacggaa
     3001 ttgttactgc caattatcag actgggcatc cccatggtta tattagtgca atgtatcgag
     3061 gagaattagc gattagcaaa atactatatg ctaagaatga aagcttatgc gaattaaaaa
     3121 aacaggcaga aacttatccc aatgctttgc agaaaagttt agttaacttt tttatgtttg
     3181 aagcagggtt ctctttaatg tttgtaaaag caaattcggg aacagacgat aaatattata
     3241 ttgcgggtca tgtttttcgt atagtttcat gtttaaatca agtgttattt gcatgtaata
     3301 atgcttattg tatcaacgaa aagaaagcta taaaactgct tgaaactttt gaacataaac
     3361 ctgaaaaata taccgagaag gtaaatcata tttttgaagt actcggtatc tcacttttgg
     3421 aatgctacga catgaccgag aagctttata atgaagtgaa tgaaattgta tcggagataa
     3481 ataacttttt aaacgaggag agttcagatg aaagaaaaca aatatgatga taatatattt
     3541 tttcaaaaat acagtcaaat gagtcgctcg cagaaaggac tggctggtgc gggagaatgg
     3601 gagactttga aaaagatgct acctgatttt aagggtaagc gtgtgcttga tttaggatgc
     3661 ggctatggat ggcactgtat atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt
     3721 gatatttctc ataaaatgct cgaagtagca aaaggaaaaa cccattttcc acagattgaa
     3781 tatgaatgct gtgccataga agatgtggat ttcccagagg agagctttga tgtaatacta
     3841 agttcgcttg cgtttcatta tgtagcagac tatgagaatt taataaaaaa gatatatagg
     3901 atgctgaagg ctggtggcaa tttagttttt acagttgaac atcctgtttt tactgctcat
     3961 ggaacacaag actggtatta taacgaaaaa ggagaaatac tgcatttccc ggtggacaat
     4021 tattattatg agggcaaacg gacagctatg tttttggaag aaaaggttac aaaatatcat
     4081 agaacactga ccacatatct aaatacactg ctttcaaata gttttataat aaatcagatt
     4141 gtggagccac agccgccaga gaacatgatg gatattccgg ggatggcgga tgaaatgcga
     4201 cgcccaatga tgctgattgt atcggcaaaa aagaagatgt aataatatag aaaaaataaa
     4261 cgaggagtat gtaaatgaga tcagaaaaag aaatgatgga tttagtactt tctttagcag
     4321 aacaggatga acgtattcga attgtgaccc ttgaggggtc acgcgcaaat attaatatac
     4381 ctaaagatga atttcaggat tatgatatta catattttgt aagtgatata gaaccgttta
     4441 tatctaatga tgactggctt aatcaatttg ggaatataat aatgatgcaa aagccggagg
     4501 atatggaatt attcccacct gaagaaaagg gattttccta tcttatgcta tttgatgatt
     4561 acaataaaat tgatcttacc ttattgccct tggaagagtt agataattac ctaaagggcg
     4621 ataaattaat aaaggttcta attgataaag attgtagaat taaaagggac atagttccga
     4681 ctgatataga ttatcatgta agaaagccaa gcgcaaggga gtatgatgat tgctgcaatg
     4741 aattttggaa tgtaacacct tatgttatta aaggattgtg ccgtaaggaa attttatttg
     4801 ctattgatca ttttaatcag attgttcgcc atgagctgct gagaatgata tcatggaagg
     4861 tcggcatcga aacaggcttt aaattaagtg taggcaagaa ctataagttt attgaaaggt
     4921 atatatccga ggatttgtgg gagaaacttt tgtccaccta ccggatggat tcctatgaaa
     4981 acatatggga agcattattt ctatgccatc aattgttcag ggcggtatcc ggtgaggtgg
     5041 cggaaaggct tcattatgcc tatccggagt atgataggaa tataacaaaa tataccaggg
     5101 acatgtataa aaaatacact ggtaaaaccg gctgcctgga tagcacatat gccgctgata
     5161 tagaagagag gcgggaacag tgattacaga aatgaaagca gggcacctga aagatatcga
     5221 taaacccagc gaaccatttg aggtgatagg taagattata ccgaggtatg aaaacgagaa
     5281 ttggaccttt acagaattac tctatgaagc gccatattta aaaagctacc aagacgaaga
     5341 ggatgaagag gatgaggagg cagattgcct tgaatatatt gacaatactg ataagataat
     5401 atatctttac taccaagacg ataaatgcgt cggaaaagtt aaactgcgaa aaaattggaa
     5461 ccggtacgct tatatagaag atatcgccgt atgtaaggat ttcagggggc aaggcatagg
     5521 cagcgcgctt atcaatatat ctatagaatg ggcaaagcat aaaaacttgc atggactaat
     5581 gcttgaaacc caggacaata accttatagc ttgtaaattc tatcataatt gtggtttcaa
     5641 aatcggctcc gtcgatacta tgttatacgc caactttgaa aacaactttg aaaaagctgt
     5701 tttctggtat ttaaggtttt agaatgcaag gaacagtgaa ttggagttcg tcttgttata
     5761 attagcttct tggggtatct ttaaatactg tagaaaagag gaaggaaata ataaatggct
     5821 aaaatgagaa tatcaccgga attgaaaaaa ctgatcgaaa aataccgctg cgtaaaagat
     5881 acggaaggaa tgtctcctgc taaggtatat aagctggtgg gagaaaatga aaacctatat
     5941 ttaaaaatga cggacagccg gtataaaggg accacctatg atgtggaacg ggaaaaggac
     6001 atgatgctat ggctggaagg aaagctgcct gttccaaagg tcctgcactt tgaacggcat
     6061 gatggctgga gcaatctgct catgagtgag gccgatggcg tcctttgctc ggaagagtat
     6121 gaagatgaac aaagccctga aaagattatc gagctgtatg cggagtgcat caggctcttt
     6181 cactccatcg acatatcgga ttgtccctat acgaatagct tagacagccg cttagccgaa
     6241 ttggattact tactgaataa cgatctggcc gatgtggatt gcgaaaactg ggaagaagac
     6301 actccattta aagatccgcg cgagctgtat gattttttaa agacggaaaa gcccgaagag
     6361 gaacttgtct tttcccacgg cgacctggga gacagcaaca tctttgtgaa agatggcaaa
     6421 gtaagtggct ttattgatct tgggagaagc ggcagggcgg acaagtggta tgacattgcc
     6481 ttctgcgtcc ggtcgatcag ggaggatatc ggggaagaac agtatgtcga gctatttttt
     6541 gacttactgg ggatcaagcc tgattgggag aaaataaaat attatatttt actggatgaa
     6601 ttgttttagt acctagattt agatgtctaa aaagctttaa ctacaagctt tttagacatc
     6661 taatcttttc tgaagtacat ccgcaactgt ccatactctg atgttttata tcttttctaa
     6721 aagttcgcta gatagagttc tatattagag atgtaaagag ttttggtgaa gaggtttgtg
     6781 agtatggctt ttataaccag ggtgcaatga gaagcactaa cagcagctag cttaagaacg
     6841 cataggatat actttttatg gaagtcacag aggaggaata aaatttgaac aggattaaca
     6901 gagtaacctc tattcttatt cagctgcaat caaaaaaaat aattcctgcc aaagaaattg
     6961 cacagcgatt taatataagc ttaaggacag tttacagaga tatccggaca cttgaagaag
     7021 ccggaatacc aattggatct gaggccggaa aaggatattt tcttgtagag ggcttcctac
     7081 ttccgccggt aatgtttaca gcggcggaag tgggtgcatt gattacagca gggaaatttt
     7141 taaattgcca tggagatgaa tcatttataa aggattttga ttcagctatg tataaaatca
     7201 aatctatttt gaagcatggt gaaaaaaact atgcacagga gttggagaac agtattaacg
     7261 tgtacagcac atctggacag aaaaatacat tggcggataa cgttattgca gcaattcaga
     7321 ctgcaatctg caataaaagg gtaatatcaa ttcaatatcc tgcatcagga gggcaagaac
     7381 cggaaagcag aatgatagag cctatatcac tggggtttta tgaacagaac tggtacttaa
     7441 tcggttttgc aggctaagaa atgaatatag gaattttcgt gtggatcgga ttaaaagcat
     7501 ttgcatagaa gaagagctct gtcaaagcca tgatggctct ttggaacaaa tattaaaaca
     7561 aatgctttca tataaaaaac tatataatgt aattcttaga gctgaaaaag gggagacata
     7621 caattctatc aagaacaggt attctctcgg cttccttgaa gaaaccgatt tgggaagtaa
     7681 aatggaaatc gaattccaga cagattcctt tgagatattg agcaagcagc tgattgaata
     7741 tggatcaggc attgaaatag tccaacctga tgaattaaaa tgcataaccc gtaaacacct
     7801 ggcacaaatt acgaatcact gcctaaactt gatttagaga aagcgattgg tctgttatgt
     7861 attttttgta aggtttcata tcccctgctg acatacagct gtcagtgtat tatgatattc
     7921 tactatcaaa aaggaggatt gaaaaatatg aaaccaaaga taattatgca cacacaaatt
     7981 agccttgatg gccgcattaa aggctttgat aatccggaag tttactacca ggttgccggg
     8041 ggaattcatt cggatgcggt gctgtttggg tccaatactg tttttactgc atttgaaaaa
     8101 tatcctgctg aaacagaggc tgattttgga taaagtccgt ataattgtgt aaaagtaaaa
     8161 aggccatata acagtccttt tacggtacaa tgtttttaac gacaaaaaca tacccaggag
     8221 gacttttaca tgacccaagt acattttaca ctgaaaagcg aagagattca aagcattatt
     8281 gaatattctg taaaggatga cgtttctaaa aatattttaa caacggtatt taatcaacta
     8341 atggaaaatc aacgaacaga atatattcaa gcaaaagaat atgaacgaac agaaaaccga
     8401 caaagtcaac gaaatggcta ttatgagcgc agctttacga cacgtgtagg cacgctagaa
     8461 ttaaaagtac ccagaacacg tgatggccat ttttcaccca cagtgtttga acgttatcaa
     8521 cgaaacgaaa aagccctcat ggcttcaatg ttggaaatgt atgtatcagg cgtttcaact
     8581 cgtaaagtat caaaaattgt ggaagaactt tgtggtaaat ccgtctctaa gtccttcgtt
     8641 tctagcttaa cagaacagct agaacctatg gttaacgagt ggcagaatcg tttattatca
     8701 gaaaaaaatt atccttactt aatgaccgat gtactctata taaaagtacg agaagaaaat
     8761 cgagtactct caaaaagctg tcatatagcg attggaataa ccaaagatgg cgaccgtgaa
     8821 attatcggct tcatgattca aagtggcgaa agcgaagaga cctggacaac attttttgaa
     8881 tacctaaaag aacgcggttt acaaggtacg gaactcgtta tttctgatgc gcacaaagga
     8941 ttagtctctg ccattagaaa atccttcacc aacgtaagtt ggcaaagatg ccaagttcac
     9001 ttcctaagaa atatct
//
LOCUS       DAZKCW010000084         8455 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000084 DAZKCW010000000
VERSION     DAZKCW010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.087"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(56..349)
                     /locus_tag="ACG84Z_002454"
     CDS             complement(56..349)
                     /locus_tag="ACG84Z_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFP9163253.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(377..1042)
                     /locus_tag="ACG84Z_002455"
     CDS             complement(377..1042)
                     /locus_tag="ACG84Z_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFP9163254.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1182..1814)
                     /locus_tag="ACG84Z_002456"
     CDS             complement(1182..1814)
                     /locus_tag="ACG84Z_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFP9163255.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1821..2888)
                     /gene="liaS"
                     /locus_tag="ACG84Z_002457"
     CDS             complement(1821..2888)
                     /gene="liaS"
                     /locus_tag="ACG84Z_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFP9163256.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            complement(2885..3616)
                     /gene="liaF"
                     /locus_tag="ACG84Z_002458"
     CDS             complement(2885..3616)
                     /gene="liaF"
                     /locus_tag="ACG84Z_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFP9163257.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAV
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(3784..4263)
                     /gene="greA"
                     /locus_tag="ACG84Z_002459"
     CDS             complement(3784..4263)
                     /gene="greA"
                     /locus_tag="ACG84Z_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFP9163258.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4399..5574)
                     /gene="mltG"
                     /locus_tag="ACG84Z_002460"
     CDS             complement(4399..5574)
                     /gene="mltG"
                     /locus_tag="ACG84Z_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFP9163259.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            5739..6899
                     /locus_tag="ACG84Z_002461"
     CDS             5739..6899
                     /locus_tag="ACG84Z_002461"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFP9163260.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KELNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            complement(6939..7886)
                     /locus_tag="ACG84Z_002462"
     CDS             complement(6939..7886)
                     /locus_tag="ACG84Z_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFP9163261.1"
                     /translation="MLNYLITGGAGFIGSTLANYLGKENNVVVIDDLSMGKKENLDES
                     KHITFIEGDVADKNLMEKVMKEYHFDYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(7919..>8455)
                     /locus_tag="ACG84Z_002463"
     CDS             complement(7919..>8455)
                     /locus_tag="ACG84Z_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFP9163262.1"
                     /translation="FNFTERHKELMNNSQHINNTQTPDNTLVRKDVAENTDISNARIT
                     IWKSAWEIFKTSWLIGVSPKNVVSYAQSIIPDGYIAKVGIAIHNAYLNVLTSTGILGI
                     IPFMAFLIKSFVLNVYRIIYNKCIGKDYHFVYCLVILSYALYAALNNELVYENTVGTF
                     VFWLFLGRVNSKNNSSYF"
BASE COUNT         2533 a         1759 c         1316 g         2847 t
ORIGIN      
        1 atattttcaa aagaaaaaag agaaggtgac aaaaattgtg tcaccctctc tttttttatt
       61 gttttttaaa gtgataggtt ggctcctcca ggttgggatc ataatcaaca agtaaatcat
      121 atcctttaaa gaaccattca tctgcttcct cgataaaaaa aagtgtccca tccatttcca
      181 ctttctttac aggatgttct ggctgttcaa ctgacattcc aatcgaaaaa ccatcatgaa
      241 cctctgtttt gccgtagact tttccaaaaa aacgtattcc gtaagtttct ggcagatcaa
      301 tttctgagtc aaaccacttt tgtgcttttg gcgttaccgt taatttcatc ccaacaacct
      361 actttctctt ttctttctat tgattcatct tatcgtctag aatatccaca tcgcctgtct
      421 ctccaataac cagtagatta tcattttcac gaacatattc atctgctgca ggagaagcga
      481 taaccgtttg atctactctt cgtatggcga ctactgttaa gtcaaaacgt tgcctgaaat
      541 ttaattcagc taatgttttg ttgaaaaatt taggattgga gactcggatt tctgctaaag
      601 aatatttatc tgacagctct aagtagtcta gaatattctt tgatactaag ttatgtgcaa
      661 tccgtatccc catgtctcgc tcagggtgta cgacacgatc tgctccgatc ttctctagta
      721 cacgggcatg gtactcattt tgggcttttg ctaaaatatt cggtacgccc atttccttta
      781 ccatcagagt aactaagatg ctggcttgga tatcttctcc aatagcgaca attacatgat
      841 cgaaatttct tatacctaat gaacgaagtg tcatctcatc ctgtgcattt gccacaacag
      901 catgggtggc tatattcata tattcattga ctcgatcttc attactgtca atagccagta
      961 cttcttgtcc agcttcgatc agtgtacggc agatgcttcc gccaaatcgt ccaaggccta
     1021 caattgcaaa attttgtttc accattttcc tcctttagta tcttcttttc tcagtataac
     1081 aaagcctttc caaaaacaaa agcaagcatc attattgtaa aaaagccaag aaaaataata
     1141 gttattttct cagcttttga ttatcctctt tatcatcgtt tttatttcac caaaccatgt
     1201 ttaaacgcat agatagctgc ttgagttcgg tcttctacct ctaacttagc taatatattc
     1261 gacacatgcg ttttgactgt tttcagtgtg ataaacaatt catccgcgat ttcctgatta
     1321 cttttccctt cagaaatcag catcaaaatt tcattttctc gattcgttaa ttcttcatgc
     1381 aatactggat catttcgccg actcattttt tccatcattt ttgttgtcac ttcaggttct
     1441 agtactcgct cgccgcgttg cgtagccctt atagcatcag ctatttcatg tgctgtagac
     1501 gtcttcaaca aatatcctgc tgctcctgct tcaattgcag gataaacttt ttcatcatca
     1561 ataaaacttg tgacgataat gattttggct tttggccaat cttttaagat tgcttttgtt
     1621 gattcgatgc catccatttc ttccatgact agatccatta aaatgacatc cggtcgaagt
     1681 gccatcgcct tttcatagcc ttgacgtcca ttttcagctt ctccaatcac ttcaatgtct
     1741 tcttggatag ataaataaga agagacgcct aagcgtacca tttcatggtc atctactaat
     1801 aaaactttta tcatctttat ctatgcctcc ttcatcaaag ggaccttggt ctccacgctc
     1861 gtaccttgcc ctttaaaact aatgattttt actgttccac caataccagc tactcgttct
     1921 ttgatattgt tcaatccata acttcccgtt ttggtttcat tcatattaaa tcctgtcccg
     1981 tcgtcaatga tacgtaataa aagattgtta tctattttat gcaaatagac ttctaattca
     2041 ttagccttag catgtcttaa tgtgtttgat aacaattctt gaacgattcg gaacaagtga
     2101 tcctcaatgg aactagttaa ttttacatct tctacctccc attttagcga aatctggatt
     2161 ttattctgca attccttcaa taactgctca atgccttgtt ttaaactttt ttcttctaaa
     2221 ttgactggac gcagatgaag aagcagcgca cgcatctcag actgggaagc gttgatgatc
     2281 tctgccacca ttttcaactg cttacggaac atttctggtg tctcactttt ttctgcttgc
     2341 tccgtcaatg ccgacatcat catcatcgct gcaaataatt gctgtgaaac tgaatcatga
     2401 agctcacgag ctaatcgatg cctttctaat tttaaaatct cttctttggt ttgtccatct
     2461 acatattgag gacggctagt cataatctgt aattcactgg atacttcgat cattttttct
     2521 tttattttag taatttccat atcaatatct ttgatgtaca gatcatccga cgcgcttggg
     2581 atcggctgat gcaaaagttt ggattcataa ttgccagaag aaagtgcacg aagcttttct
     2641 tcgattttcc cgtattttgc cttttgaata agtgataaca atagaaatac gatcaatcct
     2701 acacctaatg aaattgccat caaatggaag ataagcggaa cgtataataa acgcgcacgc
     2761 agcaattctc cccaccaatg actttggtta ctggcataaa aataagtgaa aagtgaaaat
     2821 agaataataa ggaaagccgc aatccccgaa taaacagcta gcattgcttt ggatattctt
     2881 cccatcatat tcgtatcacc tcgacatctc caaccaaagt attggtaatg atcttcaatc
     2941 tgcgaggatt ttcatcataa tcactgctgc agattttgat ctgttcgttt tttaaggaaa
     3001 actgctcttc ttcaaacaag acatttccta ctaatgtcgc atgctctaaa cgaatagcca
     3061 ctcccagggg tactaagatc cgtgttctgc ctatcccttt tcttacaatc acaatattat
     3121 catcttttgg caaaagtgta ttgcccaaat cgatgatagt atcaccagaa atgatggcaa
     3181 tgttgatatc atcccattca tagacgtcgt ttccaatacg ttggttacca aataattgct
     3241 gtcttttacg ctcattatta tgtgttttta attgctctgt ttggaccatc atgatctgtt
     3301 tttttcgcca aaaagcattt tttgtcaaat ctattcctga aatctctaca cctttcagcc
     3361 cgataaataa aacggccaat acaaccatca tccataaagc aggactgttg actaagctaa
     3421 aaaaaatgac caagctccct aagatcaatt gaaaattttg aaatttagta cgaggatatt
     3481 tgcgcacagc tagatatata ttgaaaatac cgaatattac taaaagcaaa agtccagtat
     3541 tgtttacgat ttgccaaaca gcaaataaca gcagcagtgc ttcgactacc acaaaaaaac
     3601 gccaagaact attcatcgct ttttctccct cctgacacat tctcatttca tcatacctat
     3661 ttttttgact gttggctata ggactttaga tgtaagatcg ttcagtgaaa cctgcaatac
     3721 tcaaagagaa aagatctaga gtgcgtcatc agtaagatga actctctaga tctttcagtc
     3781 agactacgct tgttctactt tgacgatttt aactaacata tcgccacctg gtgtagcaat
     3841 ggttacttca tcatttttac gtttgccaat caatgcttgc gcgataggag aatcattgga
     3901 aatctttcca gaaaacgggt ctgcttcagc acttccgaca atcgtgtact cttcttcatc
     3961 tccatcaggc aactcgatga acgtaactgt tttaccgatc gatacctcat ctgcatctac
     4021 gccgtcatta tcgatgattt gtgcaaaacg gatcatattt tcaattgttg tgattcttcc
     4081 ttcaacaaat gcttgttcat ctttagctga ttcgtattcg gagttttcgg aaagatctcc
     4141 gaaaccgcga gcgattttga ttcgttcaat gatttctccg cgtttaactg tttttagttc
     4201 ttctaattct ttttctaatt tttctttacc ttctagagtc attggataaa ctttctctac
     4261 catgtgtaac gtctcctttt ttcgataaaa taccgcaaaa ggtaatcttt tgaggaatat
     4321 agtccaaaaa agattaccac gcttttctta aaatgtaaat gtttttctaa aaatgatcaa
     4381 tgactagccc ctgtttttct aagaattatt tacatatttt tgcactagtt ccatatgttc
     4441 ttcatacgtt ttagcgaaat aaacatttcc agtgctcgta tctgctacga aataataata
     4501 gtcattttct gctggttcta atactgcctt gattgcctct tcgcttggat tgtcaaaagg
     4561 accaggccca tagccggtat tggtatacaa attgtatggt gaatctacag ctgtatcttc
     4621 atacgtcacc aattctttat gttctcctaa tgcatataaa acagagatat ctgactgaag
     4681 tggcatattt gccttgattc ggttaaagaa gacttgtgca atatttttac gatcattttc
     4741 ttttacgcct tctttttcaa ctagagaagc caaagttaaa acttcttgta cagtcaaatt
     4801 tttctgtttg atagctgaat aatagttttg catgaccgta tttgttttgt tcaccatctc
     4861 aatcacaaga tccttaagcg aagtactcgt gtagtaatca taagtagctg ggaataagta
     4921 gccttccaaa cggtattttg tgttctcagc tttagaggca ctttccaaca attctgggaa
     4981 tttttgatac aactcgttaa agaaagtctc atcatttact aaatctaaaa attctttctt
     5041 gtctttacca gttaccttcg ctacccgctc agcaatctga tcgatgtcgt agccttctgg
     5101 aatggcaatt ttcccatctg caacttttgt tggctcagat gtgccgcctt cttgcaactg
     5161 cttgccaatc tcatcaagag tcatattagg cgctaactga taataaccag cttgaaagcc
     5221 agttaagttt ttaaattttg tataataatt gaaaacaatc ccacttttaa taatattgtc
     5281 tttctccaaa atttcgccaa tctgcttatt agaagagccg cttgggattt ccacttggac
     5341 taattggtcg tccgatttat ctaaaggctt caacccgcta tctacataac gatatacggt
     5401 aaacccgaga aatccgccaa taatcaataa tgtaagagcg atcactaaaa tgatcttcct
     5461 cacgatctta tcttcttttt tacgcagatt tctccgcttg tcgattatat ctgctgtagc
     5521 tgccttactg gcttcttttt tgtctttgct tgggtgttgt ttgtttcctg acaaaacaac
     5581 tcctccttac tatcatcttc gtaactctgt ttattataca tgaaatttct actgccgtga
     5641 attattttac caaatattat gtcaaaattg taagtggcaa atgctctttt tgaggattac
     5701 aatgaaaaat agttaaaaat ggataggaag gatttaatat ggcaaaagga aaacatcaaa
     5761 aaaaacagca gatctctctt tcttttctcg cagttttgtt gctggctgtc agcttctttt
     5821 caacaggcat cattacagga tggcaattaa caaaacaacc tcaaccacaa atttataaaa
     5881 cggaacccgc acaacttgct tccaatttaa catctaatga gcagatgctt gccagcaaaa
     5941 ttgatcaatt actgcaaaaa tcagattata tcggttcgat ttatgtacgc aaaaataatc
     6001 gagtgatatt agaaaaagga tatgggtacg caaatctacg cataaaagaa ttgaattctc
     6061 cttctcttta ctatcaaatc ggttcgatcc aaaaagcgat gactgcttta cttatcctaa
     6121 aacaaattca atctggcaag ataacttttg acacaaagct atctgaattt tatcctcaga
     6181 ttcctggaag tcagcaaatc tcaatcaaaa atatgcttta catgcgctct ggtcttcatc
     6241 gaaccgcttc tccaaaaaaa cctatgtcag atagtgagat cattcagttt gcccttcatc
     6301 atttgaaatt tactggttat gatacgtatc attatgaacc attaaattat acattgctta
     6361 caggggtatt gatcaaacta atgaatcagc cttatgaaac tcttttaaaa aaagaaatca
     6421 ttcggccact ccatctagaa catacagatt tttatgaaaa tgtaaaaaat tccccgcagc
     6481 atgctgtatc ttaccaaatg tctgcaactg acgattattc aaaagcattg gtcgagcctg
     6541 aaacagacat ccgaaatgaa ttaggcacag gaaatataag tatgtctgtt tatgacttga
     6601 acaaattctt taccagtgtt ctgtctggcg atattatacc aaaagaacta cttttctcat
     6661 tgtggcaaaa taatggtgat aaacatcctt acagcggcgg tgtttacagt ggaaatgatt
     6721 atatccttgc tcagggaaat atcaatcgat tccatgcagt agcggcgatg aaaaaagaca
     6781 caaaagatgc aatcgtcatg gaaagtaata tccaatctga taaaaacatc aaattgccgg
     6841 ccactgattt aagaaatcag atttacgaac tgatggaagg tgttaattta aaaagctaag
     6901 tcgagacaaa aaaaccagca ggatgctggt tttttgtttc aatcgatttc tgtctttaaa
     6961 taacgttcca ttccgttcaa tatatcaaat ttgggttgat aacctaaaga acggatcttt
     7021 gaaatatccg ctaaagaatc acgaatatcc cctgaacgct ccgcttcata tttaagcgct
     7081 agctctgttc ctaagatttg atcaattgaa tgaatcaatt caagtagcgt agtgcttttt
     7141 cctgtaccga cattgaattg ctgtcctaaa gctttttctt ccttagcaac aagtaaaagt
     7201 gcttgtataa catcttctat ataaacgaag tctctagatt ggctaccatc accaaataaa
     7261 gtaaattctg ttttttctcc tgccaattgt tttttgtatc ggtccactag aatcgaaata
     7321 actccgctat atggagagtt aggattttga tttggaccat aaacgttaaa aaatcggaca
     7381 gcactagtcg gaacatcata taaatgacag taatccaaaa catattgttc tgctgcaaac
     7441 ttatcgatgg catatggtgt taaaggacgg atgaccgatt cttctttttt tggcaacgtt
     7501 ggttcatcgc cataaactgc agctgatgaa ctaaatacca atcgttttaa accagattga
     7561 tattttcgta ccaattcaag caataaaagc gcactgtcaa aatttacacg atgagtttct
     7621 agaggacgtt ctacagaatc tgccacacta gctacagcag ctagatggaa aatataatcg
     7681 aaatggtatt ctttcatgac cttttccatc aaatttttgt cagcgacatc cccttcaata
     7741 aacgtgatgt gcttcgattc atccagattc tcttttttcc ccatcgataa atcatcgatc
     7801 acaactacat tgttttcttt tcctagataa ttcgcgagcg tcgagccaat gaagccggcg
     7861 ccaccggtaa tcaagtaatt caacattttt tctcctcttt tcaagataaa atttattact
     7921 aaaaatagct agaattattt ttgctattaa ctcttcctaa aaatagccaa aaaacaaacg
     7981 ttcctacagt gttttcatag actaattcat tgttaagagc tgcgtatagt gcataagata
     8041 aaataactaa acagtaaaca aaatgataat ctttaccaat gcatttatta tagatgattc
     8101 gataaacatt cagcacaaaa ctctttatta aaaaagccat gaaaggaatt attcctagaa
     8161 tacctgtcga tgttaataca ttcaagtatg cattatgaat ggcaattcct actttcgcaa
     8221 tatatccatc tggaataatt gactgtgcat aagatactac atttttcgga gagactccga
     8281 taagccaact tgttttaaat atttcccatg cacttttcca tatagtaatt ctagcattag
     8341 aaatatctgt attttcagct acgtctttcc taacaagagt attatcaggt gtttgagtat
     8401 tattaatatg ttgactatta ttcattaatt ctttatgacg ctctgtaaaa ttaaa
//
LOCUS       DAZKCW010000085         8416 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000085 DAZKCW010000000
VERSION     DAZKCW010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.088"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(108..1076)
                     /locus_tag="ACG84Z_002464"
     CDS             complement(108..1076)
                     /locus_tag="ACG84Z_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFP9163263.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            1308..2141
                     /locus_tag="ACG84Z_002465"
     CDS             1308..2141
                     /locus_tag="ACG84Z_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFP9163264.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            2175..3014
                     /locus_tag="ACG84Z_002466"
     CDS             2175..3014
                     /locus_tag="ACG84Z_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9163265.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            3040..3600
                     /locus_tag="ACG84Z_002467"
     CDS             3040..3600
                     /locus_tag="ACG84Z_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9163266.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            3799..5520
                     /locus_tag="ACG84Z_002468"
     CDS             3799..5520
                     /locus_tag="ACG84Z_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFP9163267.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            5685..6827
                     /locus_tag="ACG84Z_002469"
     CDS             5685..6827
                     /locus_tag="ACG84Z_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFP9163268.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            6843..8054
                     /gene="thiI"
                     /locus_tag="ACG84Z_002470"
     CDS             6843..8054
                     /gene="thiI"
                     /locus_tag="ACG84Z_002470"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFP9163269.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         2885 a         1455 c         1745 g         2331 t
ORIGIN      
        1 tttacgaaaa ttgtttctca aatttttgta aattttcgac ttagttttcg aagaagctat
       61 ttttgtcaca gcctctcttt ttaagtttag ctattagata atgatgttta gttttggata
      121 aacgaaatca attcttcacc cgacaaacca tagtttacag caatcaatag ttttaaacgt
      181 gctttttgac tattaatact gttacagaaa ataatcccca ttttttctag ttcttttccc
      241 ccgccttcat aatcataaac aggctctgcg attccattga aacaacgaga aacaagtact
      301 acagggattt tttggacaag aagcttttcc aaagcagcta aggcttgtgg agggagattc
      361 cccgcaccta aagcttcgat taccaaaccg tctactttcg tatgggcgat ggcttccaat
      421 aagtcccctt gcatcccagc atatgcttta acgatcggga tagtcccatc tacagcggaa
      481 atgtccagtc gctttgtttc taaaagttcc tgcaagaata aaattcgatt cttagttact
      541 aagccgatgg gacccaatgt aggtgttcgg aaagtagcaa catttgtggt atgggtcttt
      601 gtcacgtagc gtgcagaatg gatctcatcg ttcatgacca ccaaaacccc cttatctagc
      661 gcttcttcac aacttgcgac acgaatcgca ctttcaaaat tataaaggcc gtcacttcca
      721 agttcattac ttgaacgcat tgccccagtc aaaacaattg gtaatttgtt gccaatcgtt
      781 gtatcaagaa aaaaagcagt ttcttctaat gtatctgtac cgtgtgtgat caccactccg
      841 gatatacctg atgcataagc ggacaagata cgttctttta ataccaacat gtgagaaggc
      901 atgatgtgtg gtgagggaag attgaagata tcttcaacta ataattctac atgcttgggg
      961 attgtgattt ctgcatctaa taatgggttt gccacatcag gactaacacc gcccgtgagc
     1021 atgttttctt tcatggcgat cgttccgccg gtgtgtagta caagtatttt tttcatttta
     1081 cagacttcct tacgaataat tttgcatagc cgttaaatct tattgtatac tatataaaag
     1141 agttttgcta tcagtgaaga ataacgaata gcctaactta tcataaaaaa gctgacctta
     1201 ttaaaatgga aaagactcaa ccttgacctc ctaatacaat ggagtatctg gttgagtttc
     1261 ttttacaaga aagcagccaa ggaaatcaat cacgaaggtg gccggaaatg atcagaatcg
     1321 gattaacatc gtttaaagaa catgacaaat taactggtaa aaagaataac actctttatg
     1381 aatatgcagg gtttctaccc ttagtggaat tagatactgc ctattatgga attccccgaa
     1441 agtcctcagt tgagaattgg ataagtgaag tacctgaatc atttcgcttt gtagtcaaag
     1501 tctatcaagg aatcagcggt caaggagact ggaagcctta ttatcagacc gaagaagaga
     1561 tgattgcgca ttttttagat gttatgtcgc caatggtaga tgctggaaag atgttttgct
     1621 ttttagtcca attcccctca tcattcaaat gtacgaaaga aaatgtccag tacttgcgca
     1681 aacttagaaa gtggtttgag ggttatcctg tttctataga attgcgggat tattcttggt
     1741 acagcgatga atttcttgaa cgtacaagaa actttatgtc tagagccgct ttttctttag
     1801 ccatcatcga tgagccacag ttgctgaata caacgattcc ttttgatcca tttgtcacca
     1861 atccgaactt tgctcttttt cgattccatg gtaggaatgc gcaaggatgg caagcaaatg
     1921 ataaagagtg gcgtaaaaaa agaacgttat atcgttattc agaaaaagaa ctgcaagaac
     1981 tagcacatga agtcaaagta gttgattcta agacaaaaga ggtaggtgtg atttttaata
     2041 ataattctgg tggtgatgcg gctgaaaatg cattagcact gcaaaaaata ttaaatatca
     2101 agccagatgg actcaatcca acccaaatgg atctgtttta agggcttatt ttattcaaga
     2161 aaggggcgaa gtctatgatc aaagctattt tttttgatat tgacggaaca ttggtcacca
     2221 atcgttcaaa agcgttggaa tcaacaaaac aagcaattga atatgctcgg aaaaacggca
     2281 ttttatgcgg tgtagcaacg gggcgcagcc cagtaaagat caaagaaatc attgatgaat
     2341 tggaattaga tatgtatgtc gtgtataatg gtcaactggt ttttactgca gatcgcacga
     2401 ttatcgacca cccttttgaa caaaaagtat tggaacatat tgttgaattt gcagatgaga
     2461 accatcgaca aatcgttttt ggtgcgagaa atcggttaga tggatcaacg acgatgctat
     2521 taggacaatc gatttttatc aagcgactag tcagcttttt accgcgtaaa ttcccggtac
     2581 gtctgatgaa aaaaatcctc caggttttta gccctcaccg acaaaaggat cgttatgaaa
     2641 cgttagagat attaaaagaa ccaatttatc aatgtatatt gctcagtccg gagtcagaac
     2701 agaaaaagtt agaacatcgc tttcccgagt gtacgtttca gcgttcaaat acgtatactg
     2761 tagatatcat cccaaaaggt ggttcaaaat tactaggcat ccaagctttc gcaaatgctg
     2821 tcgaaattga aatggaagaa attatggcat tcggcgatca ttacaatgat atcgagatgc
     2881 tgaaaggtgt aggaattgga gtggccatgg ggaatgctca gatcgaagta aaacatgctg
     2941 cagactttgt gactcaatca aatgaagaag atgggatata cgaaggactg aaacacttcg
     3001 gtctgattta ttagtcaatg aaagaaggaa aaaatcagta tggaagcaga gacacctttt
     3061 caaaaagtag aaacattcca caaaactttt gatccaagaa gaccagagat acccacggct
     3121 tttacagaaa atgaagctca tacacgtgct gcgttcaaaa tagaagaact tgttgaattt
     3181 gttgcagcta cttcacctaa taaagaacaa ctgcatgaag ctgttatgct gctgcacgaa
     3241 gcattggata aagcagaaga aaaaatactt ggtaaaacac agtggggaag tgatccgctg
     3301 gttgaacaag tagatgcact gacagatatc ctttacttta cttatggttc tttttcatta
     3361 ctaggaatag tgcctgatcg aatattcgaa atcgtccatc aggcaaatat ggggaaatta
     3421 tttccagatg gaaaacctca ttatgaccct gtaacaaata aagtgttgaa acctgaaaac
     3481 tggcagatgg aatatgctcc agaacctaaa atcgcggcag aaatccaacg tcagattcaa
     3541 gaagcgattg ctaagaagaa atccgctgat ataggcatgt gcacaaatga aaaagagtga
     3601 tcagagtttc actatttttg ttatctttat acgatggaaa aacaaaagat tttcgtttaa
     3661 gttagtgaat gcatgaaaat agtatgctat aatctagaat agatgtcttt tgcacgagag
     3721 acgtattatt tggatttatg ccaagcagaa cgccatctgt tgcataaaag atgcatactg
     3781 aaaacggagg aaccataaat gggaaataat gttatcatcg gaatcgtcat tgcaatcatt
     3841 atagtcgcca ttgtcgtctt tttggttagt tacttgatga agaaaaaaaa ccaagatcga
     3901 ttggatgcct tagaaaaacg caaggaagaa ttatttgact tgccagtgat tgaagaagtc
     3961 gatgatgtta aaaaaatgca tctggttggg caaagccaaa atacctttcg tgaatggagt
     4021 caaaaatgga atgacatatc tacttcctcg ttcgctgaac tagaaagtca aattttcgaa
     4081 gtggaaaacc tcaatgaaag ttttcggttc ttaaaaggaa aaaaagcagt tgttgaagca
     4141 gaagctacaa tggaccaaat ggagaaacaa gtgacggaaa tccgtgaagg tctaaaggaa
     4201 ttgcgggaaa cggaagaacg caactcacta gctgttcagc aggcacttga cgtctatgaa
     4261 gaactgaaag aaaaagtcag agaagacgag catgaatacg gaccagctct ttttgaattg
     4321 caaaaacaga tcaaagtgat cgaaaaagaa tttacgcagt ttgtgacttt aaacacttct
     4381 ggagaccctg ttgaagcccg cgaggttttg gataaagcag aaaaacatac gtatgaagtg
     4441 gaagctctga tgaaaaaaat tccaccgctg tatgaggagc tccataccac tttccctgaa
     4501 caacttgaag aaatcagtga tacttacgag aaattgatgg aagaacaata tgtattccca
     4561 gaagaagatc ttgctgaaga tatcgcaaaa gtaagtcgaa gaattgaaaa ttcattagcc
     4621 aatcttgaaa aaacagaagt tgaaacggtc gaatttgaaa accgtgaaac agctgatttg
     4681 attgattcgt tatatgatat cttagaacgg gaaatggaag ctcagagata tgtaaaaact
     4741 aaccaatcaa cgattgcaga gtatatcaaa catacaacaa agaataaccg tcaattattg
     4801 attgagctgg atcacacatc tcaaagctat acattgaacc acaatgaaat tggccgtgta
     4861 cgaggtttcc aaaccgaagt ggaagaaatg gaacgtcaaa atgaacagat gattccacag
     4921 atccgtcaac acgaaattcc ttattcagaa gtgcgcacgt tctataaaac agtcttcaaa
     4981 gtcttagaag atatcgaaaa gcaacaagta gagatcgacg actcattaca tgaattgaga
     5041 aaaggcgaaa aagaagcgca agaaaagatc gatacattcg aattcaaatt gcgcagtttg
     5101 aaacgttttg tagaaaaaca acgtttgcct ggcttgccga atgattacct agaattcttt
     5161 tttgttgcta ctgaccgtat tgaagaacta agtgttgtct tgaataaaat tcgagtaaac
     5221 atggaagagg tcaatcgttt agttgctcta tgtgaagaag atctagaatt attagataag
     5281 aagacacatg atttagtaga tgcagcagca ttaacggagc aaatgctcca atatgcaaat
     5341 cgttatcgtc atacacacga agaagtgaga gaagcaattg ataaaagcta ctatttattc
     5401 aataaagaat atcactatca agaagcatta gacgaaatcg gtacagcatt agagcgagta
     5461 gaacctggtg ctttcaaacg catcgaagat ttttatttta atcatccaga cttagtataa
     5521 agcaaaaaag ttagtaaacc agcaagagca agacggatta ttgtcttgtt cttgtctttt
     5581 tttgtatatt tgaaaattga aacaagtgaa aatttcacct gctcttgaaa gcaccttgga
     5641 caaccgttat aatagaaaag aatttcaaaa aagaggggtt tcttatgata tattttgata
     5701 acagtgcaac aaccccaatc tttccgcaaa gcttagatgc atatgtaaaa accagtcagc
     5761 ggattattgg gaatccatca agcttgcatg atttaggcaa tcaagctaac cggttgttgc
     5821 agcaagcaag aaagcagatc gctgatttga tccatgtaga accagaagaa atctatttta
     5881 cttcaggcgg aacagaagga gataactggg tattaaaagg aacgatgatc gaaaaaagag
     5941 aatatgggaa tcatatgatc atttcaggag tcgaacatcc ggccgtcagc gagacagcag
     6001 aacaattaaa agaattagga atcgaagtaa gtatcgcccc agtggataaa cgcggatttg
     6061 tacgtgtcga cgaattgaaa gaattaataa gaaaagagac agtattagtc tctgttatgg
     6121 ctgtgaataa tgaagtagga tcgattcagc ccatccagga aatcagtgat cttttggatg
     6181 attttcctaa aattcatttc catgtagatg ctgttcaggc gattggaaaa gtaccattct
     6241 cgcaatggtt gacagaaaga gttgattttg caacattttc agctcataaa ttccatggcc
     6301 cacggggaac tggtttcatt tattggaaaa agggtcgtcg tttagcacca ttactgacag
     6361 gtggagggca agaaagaaat cagcgaagtg ggacagaaaa tgttccaggt attgtggcta
     6421 tggttaaagc tttacgttta tcattagaga taaaggaaca aaaacctgag cagacacaac
     6481 gcttaaaagt agctctaatc aatgcgttga agacgtatga gaaagtgacg attttttcag
     6541 aaggaactga ctatgcaccg catattttat gttttgctct aaaaggaatt cgcggcgaag
     6601 ttctcgtcca tgccttagaa gaaaaacaaa tatttgtttc tactactagt gcctgctcct
     6661 cacgtaaaca tatggcaagc agtacattgc acgcaatgca tgtaccaaat gatctggcta
     6721 catctgctgt tcgaatcagc ttagatgaaa acaattcgct tgcagaagtc gagcaattta
     6781 tgattatttt caagcagctt tataagaaat tttctgcaat caattaaaag aggagtgttc
     6841 ttgtgaaata cagtgaaatt atggtccgtt atggggaact ttcgacaaaa ggaaagaatc
     6901 gaaaaagctt tatcatgcaa ctagcacaaa atgtcagaca agctttgaaa gactttccag
     6961 aaatcaaaat ccatgctgat cgggaccgga tgcatctttt attgaatggc gcagacgggc
     7021 agctagttat tccaaaacta gcaaaaatat ttgggatcca aaatttctct ccaagtattc
     7081 gtgtagaaaa agatgtcgaa gttttgaaac aagctgttca agacatcatg aaagaaattt
     7141 atactgggaa agaaacattt aaaattatcg ctaaaagaag cgatcaccaa tttgaattga
     7201 caagtaatga attgaatcaa acattaggta atgctgtttt tgatattttc ccgcatatcc
     7261 aagttcaaat gcgtcaacca gatattccat tacgtgtaga gattcggcgt gatggcgctt
     7321 atctatcgta tgaaacgatc aagggagctg gaggattgcc cgtaggaaca agcggaaaag
     7381 gaatgcttat gctttctggg gggattgatt ctcctgtagc agggtacttt gccatgaagc
     7441 ggggagtgga aattgaagct gttcattttg ctagtccgcc gtatacaagt gaacaagcac
     7501 tgcaaaaagc aaaagatcta acagccaaac tagcacctta tgtgggaacg atccatttta
     7561 tcgaagtgcc atttaccgag attcaagaag aaatcaaaaa gtcagtgcca caaggatatt
     7621 ggatgacaat tactcgtcga atgatgttgc gtttgaccga tgaaattcgc cgtattcgtc
     7681 atggtttagt cattttgaat ggtgaatcat taggtcaagt ggcttcacaa actttgcaaa
     7741 gtatggtggc tatcaatgaa gtaacgaata cgccaatcat tcggcctgta gcgacaatgg
     7801 ataaacttga aatcattgaa gtagcagaac agatcgatac atttaatctt tctatccagc
     7861 cttttgaaga ttgctgtacg atttttgctc ctccacagcc aaaaacacgc cctcaactgg
     7921 aaaaggtcca tcaatatgaa gagcgtttag caatagatga aatgatccaa cgagcactag
     7981 ctggcttgaa gatggaagag atacaagcag aatcgtctaa tgaaaaaact gaagaatttt
     8041 cagaattgct ataagaggtt atgaaaatag tgttttgacc agagtattag agaaacaaaa
     8101 cgaaaaaata gctccatgta ttttaccgtt tttgaactaa tgtcgaagat tagctgattg
     8161 aataccattt atcaagaagt tatggaaaag ccggttcttt tttactaact gaaaaataaa
     8221 attttattta gagatcaagc tacagttgat aaatgatata aaaaagagaa tttcccatga
     8281 aatagcgagg ttgtgacaga agtgggcagc ttcaagaaat aagaaggaat ttacgaaaat
     8341 tgcttttcaa atttttgtga aatttcggct tatttttcga agaagttact tctggaacac
     8401 cgtgtatcag aggttg
//
LOCUS       DAZKCW010000086         8285 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000086 DAZKCW010000000
VERSION     DAZKCW010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.089"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            385..1308
                     /gene="truB"
                     /locus_tag="ACG84Z_002471"
     CDS             385..1308
                     /gene="truB"
                     /locus_tag="ACG84Z_002471"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFP9163270.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1312..2253
                     /gene="ribF"
                     /locus_tag="ACG84Z_002472"
     CDS             1312..2253
                     /gene="ribF"
                     /locus_tag="ACG84Z_002472"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFP9163271.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2648..3433
                     /locus_tag="ACG84Z_002473"
     CDS             2648..3433
                     /locus_tag="ACG84Z_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFP9163272.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3446..4297
                     /locus_tag="ACG84Z_002474"
     CDS             3446..4297
                     /locus_tag="ACG84Z_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFP9163273.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4421..4873)
                     /locus_tag="ACG84Z_002475"
     CDS             complement(4421..4873)
                     /locus_tag="ACG84Z_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163274.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5338..5706)
                     /locus_tag="ACG84Z_002476"
     CDS             complement(5338..5706)
                     /locus_tag="ACG84Z_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFP9163275.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5856..6338
                     /locus_tag="ACG84Z_002477"
     CDS             5856..6338
                     /locus_tag="ACG84Z_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFP9163276.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6375..7385
                     /locus_tag="ACG84Z_002478"
     CDS             6375..7385
                     /locus_tag="ACG84Z_002478"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFP9163277.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7500..8213)
                     /locus_tag="ACG84Z_002479"
     CDS             complement(7500..8213)
                     /locus_tag="ACG84Z_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163278.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2800 a         1345 c         1678 g         2462 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgttgatta
       61 agaaactgaa aaaataaata aaaaaaaacg gaaaaaagac tggaagaatg gacagtcttt
      121 tttttcgttt ttgggaagtg aaaaccaaac tatttacctg taagccaccc ataaatccaa
      181 tcaaatggtg caaagaaaaa atcttccatt ctattccctc ctttaaaaaa aacataacat
      241 gatttctatt tacgtgagca tgaattttgt tacgttttta ttgccgaaaa ataaaaaccg
      301 ttcattatga tgtcaaattc gtcagtaatt gatgcaatgt gttataataa ttcagttaaa
      361 tcaaaaatga aatggagaaa agacatggac gggttattaa ctttatggaa agaacgcgga
      421 atgacaagtc atgattgcgt attcaaatta agaaaaatct tacatacgaa aaaaatcgga
      481 catgggggta cgcttgaccc agacgtagac ggtgtgttgc ccatttgtat tggaaaagcc
      541 acaaaagtta tcgaatattt gacagattct gggaaaatct atgtaggcga gataactcta
      601 ggtttcagta caacgacgga agatcgatcc ggagaacggg tagaaacaaa accagtagat
      661 atgtctttat ctgaagaaaa aatagatgaa gtgatggctt catttattgg tgagatcacc
      721 cagataccac caatgtactc agcggtaaaa gtcaacggta agcggttata tgaatatgcc
      781 cgcaataatg aaacagtgga gcgtcctgtt agaaaggctc agatttaccg ttttatccgg
      841 acaagtgaat tgacaagaga cgaagtgaca ggaaccattt cttggcgctt cgaagtagaa
      901 tgcgggaaag gaacctatgt ccgcacatta gctgtagata caggcaagaa acttggttac
      961 cctgcgcaca tgtctgatct gacccgaaca gcaagtgccg gtatgtccca gaaagatgct
     1021 ctgacattag aagaagtagc tcaagctgtg aaaaatggga caatcgatga ttgtttgctg
     1081 ccaatagaaa aaggagtgaa acgattcaaa cgagtagata ttactgatga agtatggcag
     1141 aaagtaaaaa acggtatgag acttaattat actgtatttg cgctcccaga aatgccgtca
     1201 gaagaaattg ctttgtttta taaaggcaaa gttgtcagta tctatcagcc aaacccgaaa
     1261 gaaaaaaaca aattaaaacc tagtaaagta ttgagaaatg aggaataacg aatgaatatc
     1321 atcaagatca gacatcctta ccaatcagaa caaattccag aagacgatgt cgttttagta
     1381 ctaggatttt ttgacggcgt gcatattgga caccagaaag tcataaagac aggtatggaa
     1441 attgcacaaa aagaaggatt gaaattagca ttgatgactt tcaatcagca tccatcgatt
     1501 gtctttaaaa agatcgatcc tagcagcgtg aaatatttga ctagccttaa gcaaaaagaa
     1561 gaaaaaatgg ccgctttggg tatagattat ttatatgaag ttgattttac ttcttctttt
     1621 gctcatttag caccgcagga atttgttgat caatacatcg tagggttaca tgcaaaatat
     1681 gctgtttccg gttttgatta tacgtatgga ccaaaagaca ttgcagatgt cgctcatttt
     1741 cctgaatatg ccaaaggaag attcaaaatc gtcacagttt ctaaagaaga agaacaaggt
     1801 gaaaaaatca gctctacccg tattcgagga ttactagaca gcggacaagt aaaagaagca
     1861 gcaaaactat taggttgcac atatgaggta gaaggggtag ttgtccatgg cgatgcacga
     1921 ggcagactac taggattccc tacagcaaat gtcaaagtaa agagcacagt tcatttgcct
     1981 aaagaaggtg tttatgtatc ggaaataaaa attggggaaa tttggtatcc agccatgggt
     2041 tcaattggac ataatgatac attcggtgaa ggacgggagc tgactgtaga attgtatatt
     2101 ttggacttta atcaagatat ctatggtgaa catgtcgcag tacgctggaa tcaattttta
     2161 agagatcaag tgaaattttc tagtgtagag gaattgattg aacaactcaa agaggatgaa
     2221 caagcaacag ctgaatattt ttctcagcaa taaaacatta tgcataaaat ctcttgttta
     2281 tgtataacta gcaatttcaa taaaatgggt gataaataag cccaggaaag gggctgtgac
     2341 aaaagtcttg tcacagcctt tttttccaaa taaatggttt ttcagaagta gcttcttcgg
     2401 aaataagccg aaatttcaca aaaatttgag aagtaatttt tgtaaattac ttcttatttc
     2461 ttgaagctgg ccacttctgt cacaacctct ttctttatag aaataaaagg acactagcaa
     2521 ttcatgaaaa cgattgctaa agcgtatcat ttgctttaga ctatatatct tggtgtacac
     2581 tcactttaag acggaaataa aagttatccg taataacagg tttaggtatg aaaaaggagt
     2641 gggtactatg tataaggaat tagaaaacaa agtcgcagta gtaactggtg gctcaaaggg
     2701 gattggaaca gcgattgctc aacgattcgg gaaagaaaaa atgaatgtag ttgtcaacta
     2761 taactcggat aaagaaggag cagaaaaagc agtcaaagca atcgaagagg caggcggaaa
     2821 agcagtctct gtacaagcag atgtcagttc tgaagaagga atacagcgtt tacttgatac
     2881 ggctttagaa aattttggga cactggacgt ttggattaat aatgctggga tggaaaatca
     2941 gcatccaacc catgaactta gccttgaaga ttgggaaaga gtattaaaag tcaatttgac
     3001 tggcgttttt atcggaacga aagcggcttt aaattacttt acagagaatg ataaaaaagg
     3061 aaatatcatc aatatgtctt ctgttcatga acaaatccca tggccaacgt ttgctcatta
     3121 cgctgcttca aaaggcggag taaaactatt caccgaaacg gtagcaatgg agtacgcacc
     3181 aaagggaatc agaatcaata gtataggacc tggtgctatc cgtacaccta ttaatgcggc
     3241 aaaatttgat gatcctgaac aaaaagaact cttggaaagt atgatcccac taggacgcgt
     3301 aggtgaacca aaagaaatag cggcgacagc tgcatggttg gcttcagacg aatccagtta
     3361 tgttacaggt attacactat ttgcagatgg tgggatgact ttatatcctt ctttccaagg
     3421 tggaaaagga taagggtgaa taaaaatggg tttattgatt gcattgatcc cggcagttgg
     3481 gtgggggatc cagccactga ttttgaaaaa gattggtggc agaccaacaa atgagatatt
     3541 aggaactggt attggagccg tgctcgttgg cttacttgtt caattattcg cttctccagc
     3601 tggtatttca gtgactacat ttttgattag tttactttct ggtgcattct gggtcatcgg
     3661 acaaacagga cagtatacat ctttcaactt gattggtgtt tctaaaacga tgccaatttc
     3721 gactgcatta cagttagtcg gaacctcatt gattggtgtc ttcgcttttg gagaatggtc
     3781 tggaagtatg ggaaaaatca ttggtgcagc agcaatcatt cttcttgtat ttggttctgc
     3841 tttaacggca atcagtgatg atcctggaaa aaaaggcggt atcacaaaag gaatcagtct
     3901 attagcatca acaagtattg gttattgggt ttacagtgca ttgcccaaac tagttgatgc
     3961 aagcggactt tccattttct ttccgcaaat gatcggtgtc tttttagggg cagtgattta
     4021 tgtgattttc cgaaaaccaa ccgcattttc tgaagacaag agttggaaag caacaatagt
     4081 tggagccatc ttcagtgtgt cagcattggc ttatattttt tcagcaaatg aaaatggggt
     4141 tgctactgca tatatcatta cacagctaaa cgtagttatc tctacattag gcggtatgta
     4201 catcctgcat gaaaataaga caccaaaaga aaaaaaatta acgattatcg gattattgct
     4261 gatcgtagta ggaagcatgg tcacggtctt tatttgagga taaagatggt aaaatctcat
     4321 ttattaaaaa aatatttgtt tgaaccaaac agtaagtact tataaaaaaa tagcgctaga
     4381 atttccaaca tctctggaat ttctagcgct ttttaattgt ttaagataca agtgaaatat
     4441 ctgtctgcat caataatttt tcattgatcc attgactaaa atttacgaca tgattgaagt
     4501 taccaccgat tagtatctcc gcatgattgt ctttataaag atcgtattgt aaaagacggt
     4561 cttttttatt tgcgtaaaca tcgttatggt actggactaa ttgttctcgg atttgattga
     4621 ttgctgtaaa atcacgatac tgaaggttga aacgcatcgt gattggtgca tttagcatga
     4681 atcgctgcat ttcttttgct gcttcctctg cttgatctcc gtataggaac tcaaaaagat
     4741 tacgttcaga aaatttccat tgcccgccaa cctttgttcc ttttagtttt ccttcatgaa
     4801 gataatttct gatagaacgt gtagtaacac ctaattgttc ggctaattca tttactgagt
     4861 aaaaatcttt caatgttcac cctcctatgt gaatggttct actgacttag ttgatatttg
     4921 cttaatcacg aaatgtagaa agaacgattt taattaaggt cattgtaaaa atcaagtcag
     4981 aaaattctaa cttttctttc tctaaagaaa ttcgttctct cctaaagtga tattatattt
     5041 aaatatacct gaaaataatg ggcagtatta tgaaagatca ctgatatttt ctcgtatttt
     5101 ttccttattc aaaagttttg caggaaaatt gctgaaaaaa taattttact aagtggaaaa
     5161 ttcaaagcca ttcaatcagt gatttttttc agcacaagaa agactcctta taaaaatagc
     5221 agatactttg tcaattaagt gtttaaccag ggatgataaa aaggatagga ttgaacaaaa
     5281 cctgtataag ctgatgaata gtttcctcgc cagtaaaagg tttattcgta taaagcttta
     5341 tcgccaaaat ttatcatgac cttttttatc ttcaatatta aatgaaatca attgttcaat
     5401 caattcccag ttgattacac ttttccaagg aactttgatg acgttatccg tatatacgta
     5461 gcctgcttct tggatatttt tttcaagggc acgaatcgct gctttttccg gtgcgataga
     5521 aaaatgattt ttagcaaaac taaatgcaat aataaaggta ccatggtcag taaacatagg
     5581 ttggttccat tttacagttg tgtctagctg gggatacgtt tctgttatct tagcaaaaag
     5641 gtctttgatc ttttgttgat gttctttttc tttgatctga ttgatgatcg gctgaaattt
     5701 ttccattcta aaacgcctcc attaagtggt ttgatttatt ttaccagaaa aacaatagtt
     5761 atgtataaaa aacgaacaaa acacaagtaa tgttgtaacc gctatattta tatgataaga
     5821 tgtctcaaat aataaaatag aaaagagaca taaaaatgat tgacttggca aagaaattct
     5881 tacacgaaaa tatatatttt gagttgtatc atcatcgagc catttataca aatgaagatg
     5941 ctttggtaat aaagaaagaa caaggattta caggtacaga gaccaaaagc ttattcttaa
     6001 aagataaaaa agataataac tacgtatatc tgacttttac tacgaaacaa acggatttca
     6061 aagcattagg gaagatcgtc ggtaaaaggc tttctattgt ttcatcagaa cgcatggaag
     6121 aacaaacggg acaaaagcag ggcgctgttt ctccgtttgg ttatgaaaaa cagattccga
     6181 ttattattga tgaagagctc ttatcaaatg aaaaacttgt ttttgcacca ggtagaccag
     6241 atcaaacgat ggtcatccaa acggttgact taaacaaaat catccagcta cttgagatgc
     6301 cgatattttt gatgccggca aacgaaaaaa acaattaacc aagtaaaata gtgcatactt
     6361 ggaggtgaag caacatgata agttatccat tattagaaag aaatgcaacg attggggtta
     6421 ctgcaccatc ctcaggcgta tcagaggaac accattcgtt actcgaatca gctttaaaga
     6481 gaatggaaga aaaatctttc caagtagtta ctggaaagac gctttggacg caagataagg
     6541 aaaaatcagg tccagcaaga aaacgagcag atgaattcaa tcaaatgatg caagatgaaa
     6601 atatccaaat gatctttccg ccttggggag gagaattatt gattgagatt ctcgattttg
     6661 tcgattttga tgctctacaa ccaaaatgga tagtaggtta ttcagatatt agtacgttgc
     6721 tacttgctgt cacattaaaa acagggatag ccactgcaca tggaaccaac cttattgatt
     6781 taagaggaga gtacttggat gaaacgacag caatgtggga aagtgtactg aaaacaagag
     6841 aaggagaatc gattctacag caaccttctg aaaagtatca aaaagagtgg ccccatgagc
     6901 attcatcatc ttctgttttc catctcactg aaccaacaaa ttggcaatca gtcagcggag
     6961 atgcagtaag gatgaaggga cgattattag gtggctgtat tgatacgatc agtcatttaa
     7021 tcggtacccc ttatggagat gtccaatctt ttaaaagaaa gtataatgat ggaaagccga
     7081 tcttgtggtt tctagaaaat tgtgagctat cgtcagttga tttaagaaga tcacttgttc
     7141 agatgaaact ggcaggatgg tttgatggca gctcggggat catgttcggt agaagtgcag
     7201 cagaggattt gttagattat aaaatgaagg atgtatatga agatctgtca aaggaattaa
     7261 aactaccgat cttgtatgat attgattgtg gtcatgtacc gccacaactg acattgatca
     7321 atggtgccta tgcagaagta gcggtagaag atagaaaagc gactgttttg caaacgttta
     7381 tttaaaaaat tttttcctgc cttggagttt atcaaagacc aacaaatcta aatagaaaag
     7441 aaaatgaaag aagctgacag tattttgcca gcttcttttt gtatgatcta ttagaaattt
     7501 taattatcca taactatcac attgatcagc tgtttcacat catttggatt acctgtagga
     7561 atagctacta cagatgcatt atcaataatt tcttgagttg tttctctaat gaacgctgga
     7621 taagatgttt gatctgcagg catttgccaa tgtgaaggaa ctggataact agtgattgtc
     7681 ccgtcatggt tacttgaata cactaaaact ccctggtaac tgtatttccc agtgagcata
     7741 accacatctt tcggatagac tgcactccct gcatcataag gggcgatagg tgttcctgca
     7801 ggataatgaa taacatgtag ttcgaaatca cccgatgtat ctctaaaagt attacctcta
     7861 attgctagcc aaacacgtgc gtactcaatt tgtagatcag aatatcctgc taacggatct
     7921 attgactgag aagactgtga ggaagttgtg tctattgttg aagaagaaat atttgtctca
     7981 actgtactac tagatgtaga agaagtattg ggctctgaga ctttactgct tgttgaagat
     8041 gtattcgttt cagtagaagc tgatttctga gtacttgatt tttcagctga actggtttgt
     8101 ttgattgaac ttttgtctgt ggtcgcagat ggatcactat tttctttact aggagacgta
     8161 catcctacaa ggaataaaga gaccaacaat aaaataaaac ctaacttttt catataaaat
     8221 acctcattat ttttttaata ccagtatagc ataatcctga atttttgaat ccgtaaaacc
     8281 ttgtc
//
LOCUS       DAZKCW010000087         8273 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000087 DAZKCW010000000
VERSION     DAZKCW010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.090"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            476..1339
                     /locus_tag="ACG84Z_002480"
     CDS             476..1339
                     /locus_tag="ACG84Z_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFP9163279.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="ACG84Z_002481"
     CDS             complement(1468..3090)
                     /locus_tag="ACG84Z_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFP9163280.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="ACG84Z_002482"
     CDS             3339..3860
                     /locus_tag="ACG84Z_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFP9163281.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG84Z_002483"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACG84Z_002483"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFP9163282.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="ACG84Z_002484"
     CDS             5941..6759
                     /locus_tag="ACG84Z_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFP9163283.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="ACG84Z_002485"
     CDS             complement(6862..7059)
                     /locus_tag="ACG84Z_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163284.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="ACG84Z_002486"
     CDS             7228..7806
                     /locus_tag="ACG84Z_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFP9163285.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="ACG84Z_002487"
     CDS             7901..8038
                     /locus_tag="ACG84Z_002487"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163286.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2489 a         1485 c         1632 g         2667 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ata
//
LOCUS       DAZKCW010000088         8266 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000088 DAZKCW010000000
VERSION     DAZKCW010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.091"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            199..444
                     /locus_tag="ACG84Z_002488"
     CDS             199..444
                     /locus_tag="ACG84Z_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163287.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            complement(628..1377)
                     /locus_tag="ACG84Z_002489"
     CDS             complement(628..1377)
                     /locus_tag="ACG84Z_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFP9163288.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            1563..2267
                     /locus_tag="ACG84Z_002490"
     CDS             1563..2267
                     /locus_tag="ACG84Z_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFP9163289.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            2307..2864
                     /gene="hxlB"
                     /locus_tag="ACG84Z_002491"
     CDS             2307..2864
                     /gene="hxlB"
                     /locus_tag="ACG84Z_002491"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HFP9163290.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            2872..4011
                     /locus_tag="ACG84Z_002492"
     CDS             2872..4011
                     /locus_tag="ACG84Z_002492"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008926 - mannitol-1-phosphate
                     5-dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0019594 - mannitol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFP9163291.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEIYSLLSEKEQENFDEYAYFVNTAIDRQ
                     SLGKVLGGKMISVVEPYYEWIMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAA
                     HAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKT
                     LNRHGNQKLSDEITRVGSSPIRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYR
                     NLADPEAEQLRRMIVNDGLKATIKKISRLEGKLLNEVVAAYESQI"
     gene            4023..4454
                     /locus_tag="ACG84Z_002493"
     CDS             4023..4454
                     /locus_tag="ACG84Z_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFP9163292.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            4468..5913
                     /locus_tag="ACG84Z_002494"
     CDS             4468..5913
                     /locus_tag="ACG84Z_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HFP9163293.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
     gene            6199..7824
                     /locus_tag="ACG84Z_002495"
     CDS             6199..7824
                     /locus_tag="ACG84Z_002495"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFP9163294.1"
                     /translation="MKKIYSKEIDCFRGIAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
BASE COUNT         2795 a         1196 c         1649 g         2626 t
ORIGIN      
        1 tctatttaat cacatttgat tctaaaaaag aaacaaaaat aaaagtcatg tatatggtgg
       61 tcaaaaagta aataatatca gttatcaaat ttcctgtaaa ttttcttgaa actacagcat
      121 attattactt caaaacaatc tacatttttt ataaaaaagg aaatgaataa ctgaaaaaat
      181 tattatagga gagaaaaaat gtcaaaatct aaaaaaaata tcaccataat tggtttaggc
      241 ttaaccgtat atttatttac agaatttgtt tatagacatg tgaatttatt tgcagaacct
      301 ttatttgtat tatacgaatc aaattcctca atcgtcagtg aacttgctaa tttaatgata
      361 gcattgctgt ttactcccgc gttgagagtc ataactattt tggtctgttt agtgctattg
      421 ttttttgtta ataaaaagaa ataacgtagt atttcaaaag acaaagaagt gggatgatga
      481 ttgctatagt atgttatacg tggtgctagg taagtgagaa taaacaaaaa aggaaacacg
      541 caataaagtt tatttcaaaa ctttattgcg tgtttctttt ttagattttt tatatctgtt
      601 gctttagtag ttaccaatag ttttcgctta atcaatcaaa acgatttttt gtttattgta
      661 ttctttacga accttttcag gaatttcttc tgaaataaga taggtaaggt cttcaattgg
      721 accgacgata tgattactga tggtgccgaa tttatcatta gttatcatcc caagtacttc
      781 agtagaaata cgtatcatct cacgtttaat gtcggattct tgcatagttg gcacgctcgt
      841 tccaacatct agatctatgt tataaatacc cataatataa aggtcggctc gaatgttttg
      901 tagttgctta taagcttgta ccccaatatt gatcatagat tgtttataaa aagtaccgcc
      961 aatattgata atttccaaat taggatgctg tgctaatgct atggcaatcg gcgggctatt
     1021 ggtaatgatt gttgcacgaa aatcttgtgg gatttctttt gctaaagcca agttagttgt
     1081 acttccatca atgatgatga cagattcttc ttttaaaaaa gggagggctt tatgagctaa
     1141 tgcagttttt tgttcgctag ctacagtttc tcggtagtta aaattggtaa ttggcggacc
     1201 aacacgtaaa gcgccgctgt gtactctttt taagagacct tggctatcca aatctttcaa
     1261 atctcgtcga atcgtgtctt cggatacatt gaaacgttga cttaaatcac tagcgataac
     1321 tttttgttct gcgtttaata aatctagaat tttttgatga cgttctaatt tcaacatgtt
     1381 gcgtgctcct tcttatttat tcttgtttat catgtcattt atgcgttttt atgtcaataa
     1441 tttccgtttt taatacacta aaaaggcata aacaagcaaa aacaaaatat ttttatgcag
     1501 ttttatgttg actagtattt gttaagcggt tacaatgagg gggtaattaa aggagggaat
     1561 gtatggagaa aaaaattatt ttgtcgcctt cacttatgtg tggggatcta gcaaatttgg
     1621 aaggaagcat ccaagaacta gaaagtattg ggatggattc cttgcatatt gacgtgattg
     1681 acggttcttt tagtcccagt atgcctttag ggatcgaaac aatcaaaaga attagagaaa
     1741 tcacttcaat gaattttgat gtacacatca tggctaagga taacgataac gaatttttta
     1801 ttggagaaat gttgaaaatt ggcgtagaga gcattacttt tcattatgaa acaagcctcc
     1861 atattgatcg atatatccag ctcatcaaga attctggaac aaaagtaggg atagctttga
     1921 atccagcaac tccgttaaat gtattacaat atattttacc cgagattgat aggatttgtt
     1981 tgatgctgat taatccaggt tttgcaacaa acaagtcaga aaaacaagtt tcttacgcgc
     2041 taaaaaaaat tacagatctt tgccagttag taaatgagaa agagttagca gtagatatcc
     2101 aagtggatgg acgggtatcg ttagaaacga tcccgggatt attagatgca ggcgcaacaa
     2161 atctggtatt aggaagtaca agtttgtttc ttaaaggaaa tacattagca gaaaatcaaa
     2221 aactacttta tcaagcgatg aagcaatcag ttaggaaaaa tcaatagatg tagtggtcct
     2281 gaataataga aatggagggg aaatagttga gttataaggc ggcgaaacaa aatattgtaa
     2341 gagaaattac tgaaacatta gaccgtattt cttcaaaaga tgtggaacaa ttgataaaga
     2401 aaattgaaaa agcggaacga gtttttttcg tgggggttgg cagagtactg ttagcgctag
     2461 aaggaatggc aaaacgctta gggcatctag gaattcagac agtagtcgta ggacaaatca
     2521 ctgaaccggc aattacagat aaagatttat tgattgttgg ttctggtagt ggggaaagtg
     2581 ctttcccact aactattgca aaaaaagcaa aggaatttgg gtcccaagtt gcccatatag
     2641 gatcaaaccc agacagcaca atgaaagaat attcagatct ttttattcgt atacccgtac
     2701 aaacaaaatt agcgttacca gaggaaattt cttctataca gccaatgact agcctgtttg
     2761 aacaaagtgt tcttttgtta ggagatagta ttgctttagt gatgatagaa gaaaaagcaa
     2821 ttgatatgtc aaagttgtgg caataccatg ctaacttaga gtaggtgaaa aatgaaagcg
     2881 gtacattttg gagcagggaa catcggcaga gggcttattg gacaaattct acatcagaat
     2941 ggattcgatc tatgttttat tgatacgaat cctgaactga tccatcaatt aaatcaagat
     3001 aagggttata ctatcgaaat tattgatgaa atgaacagga gtgatttcat tgatcatgtt
     3061 gtggcactga atagtttatc cgagctagaa gaggtgatta cagcaacaaa aaatgcagat
     3121 atcttaacaa catctgttgg cgcaataaat ttagtaaaaa ttgcaccgat cattgcgcaa
     3181 gccttaagta agcgatttga acaaaagcat agcatcaata tcgtagctaa tgaaaatgtg
     3241 ataaatgcaa gtgatgtgtt gaaaaaagaa atttattctt tgctgtcaga aaaagaacaa
     3301 gagaattttg atgaatatgc atattttgtg aatacggcaa tcgatcgaca atctttagga
     3361 aaagttcttg gaggaaaaat gatctctgtt gtcgaacctt attatgaatg gataatggat
     3421 cgacagcagt tagatccaac tacatctttt gatatgaaaa atgtaaattt ggttgatgat
     3481 atggagcctt acattgagcg aaagctttat atcgttaatg ctgctcatgc ggcagtagct
     3541 tatttaggcg cactgaaagg atataagacg attcaagaag caatccaaaa tatggagatt
     3601 ttcaatctag tcaagcaatt tttaatggag aatatagagt actttgtaca aaaatatcat
     3661 ttttctagag aagaattaac atcttttgtg gaaaaaacat taaaccgtca tgggaatcag
     3721 aaactctccg atgaaattac tcgtgtagga agttccccta ttcgaaaatt aggccctaat
     3781 gatcgtttaa ttgctcccat agtaaaacta gattcatatc atttacctta cgatgcagga
     3841 ataaaagtaa ttgctgcggg atatcattat cggaatcttg ctgatccaga agctgaacaa
     3901 ctacgtcgaa tgattgtaaa tgatgggttg aaagcaacga ttaaaaagat ttctcgtttg
     3961 gaaggtaagc tgctgaatga agttgtcgct gcttatgagt cccagattta gaggaggaga
     4021 atatgctaaa agaacaattg tcaggaaata caatgtttat ggatgcgatc gattcatggc
     4081 aagaggcaat ccgagtaagt gcgcgtcctt tgataggaaa gggaataata gaggaaagct
     4141 atgtacaagc gatgatacaa aatgtgttgg ataacggaaa ttatattata ttactgccac
     4201 tagtagcaat gcctcatgcg cgtccagaat ttgggagcaa aggggtcggg atgagctttt
     4261 tatgtttaga taagccagtc atgttcccaa gtgaagaacc agtaaaattc ttctttacct
     4321 tttcttctga ttcgccaaag ggacatttag acttaatggc caatcttgga gaattgctga
     4381 gtgatgaaaa aatgtatcaa aaattattcg atgtgaagac agaaaaagca ttgttagatt
     4441 tgataaagaa gtaaaggaga gaagaaaatg gaggtagcaa acaaaaaaaa acgagtctcc
     4501 atgcgagcta aagttcaagc gattggcggt ttcttaacaa atatggtatt gccaaatata
     4561 ggcgcattta ttgcatgggg aattgttact gcattattca ttccaactgg gtggttccca
     4621 aatgaatctc tgaatgaact cgtaagtccg acagtcagct atctattgcc gttactactt
     4681 gcctatactg gtggtcggat ggttggtggt acacgtggag ctgttttagg tacaatcgga
     4741 acaataggtt tgattattgg tgctgacata ccaatgttca tgggagcaat gattatgggg
     4801 ccacttggtg ggtggatgat gaaaaaaaca gatgattttt tagatgggaa agttcctgct
     4861 ggttttgaaa tggtcgtcaa taatttttct ataggaatta ttggtttcat actgatgtgc
     4921 ctttcttatc tggtagttgg accaataatc caatcagcta atcaatttgt aacgagtgca
     4981 attgaagcat tagtttcaac tggtttttta ccgatactgt ccttaatcaa cgaaccggca
     5041 aaagtcttat ttttaaataa tgttattgac caaggtgttt attatccatt aggtatgcaa
     5101 caaacattag aggcaggcag atcaatttat ttcatggtag catcaaatcc tggccctggc
     5161 ttaggactat tgttagctta ttctttattt ggtaaaaagg cagcaaaaca gacagcacca
     5221 ggtgcaatca tcatccattt tttcggcgga atacatgaga tttattttcc atatgtatta
     5281 atgaaaccac tcactatatt atctatgatt gctggtggaa tgacaggaat catcactttt
     5341 gaattatttg atgcgggcct ggtagcaggt ccaagtccag gttctatttt ttcttattta
     5401 gctctaacgc ctcggggaaa ttttttgggt gtcatggcgg gagtggtcac agcaacactg
     5461 gtttcctttt ttgtaacatc agtaatttta aaagcagata aatcaacaga tgaagacaga
     5521 aattttgaac tatcagttca aaaatcgaaa acgatgaaat cagaaggaag aaaattatta
     5581 aaagaagaaa atgctagaga aatatgtacc gagaaaaaag agatgaataa aatttccttt
     5641 gcttgtgatg caggaatggg aagcagcgca atgggcgcaa caatattcaa gaaaaaattg
     5701 caaaaagcag gtattactga tgttgagata aaaaattatc gaattgaaga ggtaccagaa
     5761 gatagtgatt tggtgatcgt acatcaagat ttggaggaac ggactagaaa agcacatcct
     5821 aacatgaaaa ttgtgacatt aaagaattat ttgcaagatc cagtaatcaa tggattagca
     5881 gaagaaatca ttggattaaa aacagaagac taatttatgg gaatttttga ttaaccttta
     5941 ttaaaattat tttgcctaat ataaaaaggt tgtgacatgg cttgtgtcgc aacctttttt
     6001 tgtcgcacaa ataattaatc ggatatttta tgttcatatt ttttgtgatc aacgagaact
     6061 gatggggcaa agatacattt tagatacttt taactgttaa tttacaaaac aaggtgaaac
     6121 gaatagaaaa atgaaaaaat cgatacggaa gaatatgttt gattaaaaca tgcatgaaga
     6181 gaaggaggtt gatgatacat gaaaaaaata tattcaaagg aaatcgattg ttttagaggc
     6241 attgctgttt tagcagtgat attttatcat ttgccaaata gtttgctgcc aggcggattg
     6301 caaggagtaa cgatcttttt tgtggtttct ggttttttaa tggctaaaaa tacgataaga
     6361 gatgaaaaaa acagacaatt cagtttttta catttttact ataagcgtat caaacgtatt
     6421 tatccatttt tactgttttc tttggtcgta ttcattttca tactagggat tagcaacatt
     6481 cgattgatag gaaacattcg tagtgagcta cccagtttga tttttggcta taacaattgg
     6541 tggcagctga atcaaggagt atcttatttt gactcttact ttaatgcttc tttatttaaa
     6601 cattattggt cgctttcagt tgaactacaa ttctatttga tatggccatt tttgtttatt
     6661 gtcattaagc gtatgagaag aaaacaagtg ttttacttaa tctatacatt gatttttgtt
     6721 tctattcttt ttagtttgtt tttaccttca actaaggcat attatcatac gatagctaaa
     6781 ctttttccat ttttattagg agtttggggg tattttaatc gaataactat tggccgtttc
     6841 tttgaacaaa acacttttag taaaatctgg cttttattac tagctagtct ttgtctgatt
     6901 ctgttcccga tttttcctta tacactaaat gaactactga tcagtatttg ttttgctcta
     6961 ttgttagcca gtgtcgatga tatgaacatt gcaaaaaaga ccaaaatcgc tagtacaaaa
     7021 ctttcttttg taggaaaaat cagttatgaa ctttatttgg tgcatttccc agtattgatt
     7081 gctctgacaa atctattcaa acatcaccat tggaaatatt tggatatcgc aggtctattc
     7141 actgtgtttt tatgtacatt actcatgatt acttgcttta gaaaaggagt gcaaaagatg
     7201 agatcaccca aaatttggac agctatggca ctaatgataa tcggagtttc tgtactggta
     7261 ttacgtgctc ctgccagtcg actgaccgct gaccaaaatc agttgcaaag tttattaaaa
     7321 gaaaactcta gtaaagcaaa tgcaggagaa aatctgttgt cacaagagaa gaaaatatta
     7381 tttatcggtg attctgttat gctgggggcg tatcaggaac taaaggagac atttaaaaaa
     7441 gaagcattgg tagatgcaaa agaatcaaga caaatcactg cgttaccaga aatcttaaag
     7501 gagcataaag atttagtttc ttaccaacaa atagtgatcg ggttaggaac caatggtgtg
     7561 ataacagatg aagctataga acaaacaatg tctttgctga aagataaaaa agtatactgg
     7621 gtaaatataa aagcaccaac tggctggcaa gatacgataa atgccacatt agctacattg
     7681 ccaaatcagt attctaatat aacgatgatc gattggtata gtgagagcaa aaatcatcct
     7741 gaattttttt atgatgatga aacccatttg aatgaaagtg gacgtacagc ttatgcaaag
     7801 tatattgctt cagttattca ataaggtagt gattacgtgt gttaacctta ctttttccta
     7861 ataggtgaat caatttaaat aaaaaatact tcatatgata aacggtgttt aagaggagga
     7921 gctttttaat attcgtggta aaaaagagat gggcgaggtc gttaactgag agcttcttgg
     7981 aaagaaatcg ctttggattt atcctctttg ttatacagaa catgagcgag acgacaatac
     8041 taggatgtat gttctgatcg aagttttatg gttacaagca gcaatcagct tagataaaat
     8101 taaggatcgt aggaaccaag taaagaaggc tgttagtaaa gaaacaaacg atcaagtatg
     8161 ttttactctt aagaagatgc agtgaataaa taatagtaat ataatgctag aagggactgt
     8221 gacaaaagac gtgtcacagc cttttttgtt attttaatta tcgtcc
//
LOCUS       DAZKCW010000089         8205 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000089 DAZKCW010000000
VERSION     DAZKCW010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.092"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(155..1963)
                     /gene="uidA"
                     /locus_tag="ACG84Z_002496"
     CDS             complement(155..1963)
                     /gene="uidA"
                     /locus_tag="ACG84Z_002496"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HFP9163295.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(1986..3752)
                     /locus_tag="ACG84Z_002497"
     CDS             complement(1986..3752)
                     /locus_tag="ACG84Z_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HFP9163296.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(3765..4559)
                     /locus_tag="ACG84Z_002498"
     CDS             complement(3765..4559)
                     /locus_tag="ACG84Z_002498"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9163297.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(4569..5945)
                     /locus_tag="ACG84Z_002499"
     CDS             complement(4569..5945)
                     /locus_tag="ACG84Z_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9163298.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILGLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(6065..6712)
                     /locus_tag="ACG84Z_002500"
     CDS             complement(6065..6712)
                     /locus_tag="ACG84Z_002500"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HFP9163299.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(6796..>8205)
                     /gene="uxaC"
                     /locus_tag="ACG84Z_002501"
     CDS             complement(6796..>8205)
                     /gene="uxaC"
                     /locus_tag="ACG84Z_002501"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFP9163300.1"
                     /translation="FLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQYKNLTQ
                     VWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPIFEWSHL
                     ELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDDPTDDLW
                     YHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGLKQALSQ
                     RVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQFVTGIQL
                     HLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVALFDTAE
                     KSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMRQQLTTM
                     AQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYLSQIVEN
                     ICYRNAYNYFNFFEIGSRK"
BASE COUNT         2644 a         1656 c         1027 g         2878 t
ORIGIN      
        1 atacaacaat cagaaagccc ctttttttcg aaaaaactag aaaaaaaaca taaaaatatt
       61 tatcattctt taaacagaaa atctttctat aaaaaacaaa aaaaaacgat taggctaggc
      121 taatcgtttt ttgaacattc ttaaaaaatc caaattattt tttataactg aaattgggta
      181 ttgatgacca tcgtttctgt agatagtaag caatcatttt aggttttcta tctctagtaa
      241 agattccttt cttatttcct tgcactctta aaatcccttg acttgttgca aaatctgcaa
      301 aattccacac ttgttcacca acaaaatttt cacatgtatc tattacttcg tgatttgctt
      361 cgtaataagc cacttgatac tcttctgtaa acattgttgg tactgtatca tgaaatccag
      421 ctactgtatc tgctccatat tctgtaaaca ttattggcgt atcaggacat ctttccatcc
      481 atccatctag ctcttttttc aacagatatt ttgcatgtgc cagatcccct cccgaaacat
      541 accaaccata ataacgattt aaacataaaa catcgacaat atctcctacc ttacaaacat
      601 ctggcgttga ttttagataa gtaacgattg ttacaggtct tttctgcgga tcaagttctt
      661 tagttaattc aactaaaggt tcaaaatatt ctttagcacc ttcggaatcc gaatctggtt
      721 catttgcaat agaccacatt acaacacttg ggtggttctt gtcgcgttct atcaattcct
      781 tgatcaccgt tttatgagaa ttttctgttc gtatctcttt ccacgtatta tgtttttcca
      841 cattatcatc taataaagtg gccatgaaat ttaaatgtaa ccctactgca ggtacttcat
      901 caataactac aataccttct cgatctgcta atcgcataat ttcttctgag taaggataat
      961 gtgatgttct aaaagaatta gcacctatcc atttcattaa attaaaatct ttaatattta
     1021 cagcctcatt caaaccacgt ccattaacat acgaatcctc atgcttacca aatcctttaa
     1081 aataaaaagg tttattatta atcaaaaatt tgccattggt aacctgaaca ctgcgaatac
     1141 caaattcttc tgtataggta tcgatcactt tattatcatc aattaaacta attttcatac
     1201 tatataaata agcgtctaga ggttcccaaa aaattggatt cttaagctga atcattcctt
     1261 tctttccttc agcttcagct acaagttgag cctcttcgtc atatatcgct attaagattt
     1321 ttccggtcca ttctgtatcg atattgaatt ctacacttgc atccaaatca gttattcttg
     1381 tattaatagt aatatcactt atatagtctt tcggagttgt atataactta acaggtctat
     1441 gaatacctgc ataattgaag aaatcaaaat taactaagtt ttcctttttt atatccccat
     1501 tttcctgtac tgtttccttc ataatcccca caggtaaagt actatcgtca ataatattgt
     1561 ttacagcaac tgtaattcga ttattcccgt cttttacaaa ccgattaatt tcagactcaa
     1621 atggtgtaaa cccacctttg tgttgagtaa taaactttcc attcaaaaaa acttttgctt
     1681 catgtgttgc agatccaaaa cgaagaacta atctttcttc taataatctt ttaggaagag
     1741 tcacttcttt ttcataccac acccatccaa catgatttct aatgttctct gtttcaaata
     1801 aatcattata agaagaggga actgaaatcg gataactctc tttttcattt attggttcta
     1861 aagcaagttc ttcctgtaag tcatcatttg tatctaattt aaatctccag agaccgctta
     1921 agtcaattac ttgcctcgtc tctgtcataa tgggatacaa catataaacc actcctatct
     1981 aaatattaaa taaatgtatc ctttaaacca caataagcat ctattggact tactccctta
     2041 aattcagaaa gacccattag tttgtccacc aatatttcta aagtttcttg ttttccatca
     2101 taagtattaa tataagtctt tacttgaggt acatcagcca aatgaaacgg acactgtaca
     2161 gatacaaaaa ttgttggaat ttcatgaatg taaaacggta tatccggagt tcctttactt
     2221 gctggccaga caattcgttg aactgtgcct ggattaacat tagctatatt aatgatcaag
     2281 tcatattttt tagttaaatt tttaattggt ctcttagcag catatattcc agctatattt
     2341 ttaatttttt cttcttgcga taatcctttc aattcttctt caggtgaaat gtatttttca
     2401 acttcaaatc cttttgctga caaaatctgt ttcaataaat caatggcttg aggtctattt
     2461 ccagcaacta cttcaccaaa cccacctttt accccatgta catctactag taaaatcctt
     2521 ttatattttt ctggtacaat aggccaaata tcttgtttat ctttaactaa tgtaattgct
     2581 tggtcagcca cctctttaaa aattgattta ttttcaatta aaccaatttt ttccagagct
     2641 tcttgcttag gtaataaaat ttgttctttt gcttttttgt gtaatcccaa tttagctttt
     2701 aaccctaaaa ttctttttaa ggcatctaat aaccgatcat cagtgataat tcctttacga
     2761 tagccttcca tcatataatt aaagtcttca tctggatcat taaaaaatag aaatagatca
     2821 catccagctg caatagaagt gggcaataat tctgatcgtt tcattgcccc agtcattcct
     2881 aacatatgac tagcatcagt aactactaat ccattaaatc cgagttttcc tctaagtaag
     2941 tcagtgatta attcttttga taaagttgca ggaagtaaat cttcatcttt cagatcagga
     3001 ttaaaatgtt ttgaataagc tggcatatgg atatgacctg ccataattga aggtaatcca
     3061 gcttctatta agcctgagta tacttttcca aaagaattat cccattcttc cgtacctaaa
     3121 ctattaatac taaaagatag atgctgatct cgttcgtcaa taccgtcacc agggaaatgt
     3181 ttagctgcag gcaaaattcc actctcctga atacctttca tataagctaa actaagttct
     3241 aaaactttat cagggttttg tccaaaagat cgactagaaa tgataggatt tctccaattt
     3301 ctattaatat ctacaatagg agcaaaactc cagttacatc caatagccga tgcttcaatc
     3361 ccagaaactc tccctaattc ataagcatat ttcgcatcat ttgttgcacc aatttttact
     3421 tctacaccaa cttcagtacc atctgtacaa gctccgttac cacctgcttc cgtattagca
     3481 gcaattaata gaggaatttt actttctgtt tgtaagatat agttttgatc atatacctca
     3541 tcagcagttc ctggattata tcgtacagct ccaatatggt actgattgac catattactc
     3601 aagtaatttt tatcacgact agatcccata ttaacaaaca attgacctat tttttcttcc
     3661 aaagtcatag aatcaatcgt ctcttcaatc caagaaatag catcttcatc taaattatat
     3721 ggtttttttc gtaaatctac ttttatagtc attttctttc tcctctactt attagtaaga
     3781 tttttccaaa aagtatctat atatttttgt tcaatatcta cataatctcc cgataaacat
     3841 ttaaataaaa catcagttct taagttttcc catgattctt tttctttatt gaccaaaata
     3901 ggataaaaga aaactttatt tttatttgca gcttctagat caccaggaga atcaccaatc
     3961 attaatatct tatccaaatc acaaccattt tcaattacac ttcgaataat atcttctttt
     4021 tttcctttat cttgacaaca cagttcatca actaatgata ataattcatg tctttcccat
     4081 tcttcttgaa cagcttcctt attagctgag cttacaataa ttatcttccc atattttttc
     4141 agagctttta tagtatctct agcacttaaa aagggtttat ctaatccttt tgcttgacta
     4201 atctgttgat tgacttcttc cgaccatttt aaagctttta ataaatcctc tgactgagaa
     4261 tattctattt ccctcttcaa agatggatta gacaattctt ttgttagaga tacccagtgc
     4321 tttaatcgat taatcgatgt tacatcattt ttttctaatg ttttaactaa acctaaaaat
     4381 ctgtttattc cacgagtctc tgaatataaa ttaatattat tccaatcctg taggaatttt
     4441 tctctatgat gaacatcaaa aatctctgca gcaattggtc cgaaaaagag attgtgttta
     4501 taagtcatcg tatccataac acagccatct gaatcaatac aaaatatcca attattcata
     4561 tttctctcct atttatgttt ttgttttaaa agctcgcaat tttctaagac tttatcttta
     4621 gataatggat aaaggaaaaa taaaattaat cctacaatca gaaaacaaat tgatggaatt
     4681 aatgttgaag cgttatataa cttttctaaa acatctcccg tttgtacatt tgctaaagag
     4741 tcatagccta taatagaaag agtccaacct ccgacgcctc cagctagagc ttgacctatt
     4801 tttctagcaa aagaatatac cgcatatacg gtcccatctt ctctttgatc agactttact
     4861 tcttgatcat caataacatc agtaatattt gcccaaataa cagtattaaa cacacccaaa
     4921 cccatatagc caaccgaact aagaattaag aatacataca tattactagc ttttatcaaa
     4981 aataagatca aatatactat tgctgaaaag aacattccta ctgatgccag ttcttttttt
     5041 ccatattttt tacttaaaaa caaagttaaa ggcgaaacaa ctattaaacc caaaatagga
     5101 ttgataaaat tcattaaaac tattccctgt gcatcattat agtaatcagg aaatacataa
     5161 ttattcatac tcataattaa taattgagca aggagtaaga aaatagccgc accaattata
     5221 gaaagtaatg ccctattttt aactaaccct tttaaagatt ttaacaatga aactttgtat
     5281 tgagattggt caattcttac tcgttcagta gttagtttat aacatattaa ataacaaata
     5341 agtgcacata tcgaaaatat tcccgcaaca attgtaaaag ttgatccacc acgaactatt
     5401 tgagcgcctg aatcatctct tgtataaata aataatggtg ttaatacacc aatgaccaaa
     5461 cttgctaaag tagctccaac atttcggaat gtcgatagca ttgttctttc ttctgtaata
     5521 gaagtaatag ctgatgccat tgatccataa ggaatattta tagatgtgta aaaaatactc
     5581 ccccataata tatacgtaac atacatgtat actaccttaa cgctcataga agctgaaatc
     5641 atagaagttt gatacattaa aaaacttgct aaagcgactg gaccactcat tcttaaaatc
     5701 cacggtttaa acttaccctg cttagttgct ttcgatctat caacaatacg ccccatagtt
     5761 acatcagtaa ctgcatcgat aaatcttgct actaaaaata atgttccaac ggcagctccg
     5821 cttatcccca atacttttgt ataaaagatc attaaaaaag aactagcaaa aatgaaagta
     5881 aaatcgtttc caaaatctcc aaacatatat cctattttgt ctcttatacc aaattttctt
     5941 tccatacaat tctctccctt ctgttgttaa gcgttttcat tctgatgaaa gtacgtacta
     6001 tactctgaag cgtaaagagt cagtatttat tttttacatt tcagagtatt atttgttttt
     6061 tctcctaata attctttatc tcataaaact tatctatata tttactagct actcgactta
     6121 cttcttcaaa atcacctttt tcaacagaag ccaataaatt cccacctaca ccaactgcaa
     6181 caactcctac ttcaaaccaa tcttctaagt tctctatact tactccgcca gtaggcatta
     6241 tatttacgtg tggtaatgga gcttgatagg cttttacaat ggatggacca aaagcagaac
     6301 ctgggaatag tttaatgata tctacgccag cagtaagtgc ctcctttatc tcagtaattg
     6361 tcatacaacc tggtaaataa ggaatttgat ataaattaca aatctcagct gtttgtcgat
     6421 caaaagatgg actaacgata tattctgccc cagccataat tgcgatacga gcagtaaacg
     6481 catctaaaac cgtaccggct ccgattatta catctttttg atcagcatat tttttagcaa
     6541 tttctttgat tatttcttca gcattaggaa ctgtaaaagt tagttcaatc cctttaattc
     6601 cacccgcaat aattgaattt attgctttaa tggcctcatc cttatttttc ccacgtacaa
     6661 ccgcaatgac tccagccgct tctaacttac ttaaaatttc tacttttttc atatctatct
     6721 ccttccttta tggatacata ctttgtctag ctgtactaac ttacaaagaa taaatttaag
     6781 cttttatttc aagtattatt ttctacttcc gatttcaaaa aaattaaaat aattatacgc
     6841 attacgataa caaatattct ccactatctg actaagatac atttcatcat ctggaattcg
     6901 gcctgcttta acccactcgc ttagtaattg acataatact cgacgaaaat actcatggcg
     6961 aggatagctt agaaaacttc gagaatcagt caacatacct gtaaaattcg acaacaaact
     7021 ttgttgtgcc atcgtagtca actgttgacg cattccttca gctgtatcat tgaaccacca
     7081 agcacatccc aattggattt tttgaatcat acccccttgg aagctttgca ttgctgttgc
     7141 tagtggaagc caatcagttg gatttaatga atataaaatt gtttttggta agcacccact
     7201 cttttcagcg gtatcgaaca atgctacaac attttgtgtc aaactagctt gatcccccat
     7261 cgaatcacca ccgacatcta ctccaatttg ttcctttaat atacttgaat tatttcttaa
     7321 agcatttaaa tgcatttgca tcgtccaacc atatcttgta tactcagaca tcaaatgtaa
     7381 ttgaatacct gtaacaaatt gtgcaatttc tgataaatgg aaatccgttt ttcctgctaa
     7441 agcttttatt aacagattgt cgagtatttt ttcatctgct atttcataaa aataagtatt
     7501 caaaccgtga tctgctaatc gacagccaat ttgatgaaaa tgatccactc gttggctcaa
     7561 tgcttgcttc aacccattaa agtctttgat tggtatagcc gctgtttgac taagttttaa
     7621 aatatagttc gaaaagcctg atgatttgat actccagacc ttatctggac ggaaagtagg
     7681 taataccttg aaagaattat cctgtttaga aagctcagta tgataccaca agtcatctgt
     7741 aggatcatcc gttgtacaga tggctttcac atccatcatc tccaacaatt ctttcgggcg
     7801 ataggaatcc gtttgaattt tttcgttagc acgtcgccaa atttctggtg cattcttctc
     7861 agaaattgtc aaatcaatat caaagtaacg ttgtaattcc aaatgagacc attcaaaaat
     7921 aggattacct ggcgccttct ccactgtttt tacaaaagct aaaaattttt cataatcatc
     7981 acctggacca ctgatcaact cttcttctat accattagct cgcatcaatc gccatttata
     8041 atgatctcca gctcctttat catttaacca tacctgagtc aaattcttgt attgcttatt
     8101 ttctagcaaa tatgctgggt ctaaatgaca atgatagtcg ataattggtt ggtgttttgc
     8161 aaatttatga aaaagtcttt tagctatttc attctctaat aaaaa
//
LOCUS       DAZKCW010000090         8150 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000090 DAZKCW010000000
VERSION     DAZKCW010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.093"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            383..571
                     /locus_tag="ACG84Z_002502"
     CDS             383..571
                     /locus_tag="ACG84Z_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFP9163301.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            649..1662
                     /locus_tag="ACG84Z_002503"
     CDS             649..1662
                     /locus_tag="ACG84Z_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFP9163302.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(1729..2763)
                     /locus_tag="ACG84Z_002504"
     CDS             complement(1729..2763)
                     /locus_tag="ACG84Z_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFP9163303.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            2878..5103
                     /locus_tag="ACG84Z_002505"
     CDS             2878..5103
                     /locus_tag="ACG84Z_002505"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFP9163304.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            5121..7004
                     /locus_tag="ACG84Z_002506"
     CDS             5121..7004
                     /locus_tag="ACG84Z_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFP9163305.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            6985..7959
                     /locus_tag="ACG84Z_002507"
     CDS             6985..7959
                     /locus_tag="ACG84Z_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFP9163306.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
BASE COUNT         2644 a         1480 c         1712 g         2314 t
ORIGIN      
        1 agttagtcta cattattttg gcgatttgcc aataaggact gttgagttgt gcaaaatcaa
       61 atctgggtca gaatgaacgt cattctgtct cagatttttc gttatttcaa tttgattaac
      121 tgattgatca aaaagatttt tattttcata ttctcaaatg attcaacact aaatatacat
      181 gtttgacgcg gaaattatta ttcgattttg gcggcatcag gggggatgac gacgtagcag
      241 acccattatt ttactcaaga aaatgtccgt gcctattatt tagaatacga tagtgaacgt
      301 gctgggagtt ttgttctttt agagaaagtc tctgaagata aattagttgt cttagatttt
      361 gactgtaacg aaaaatggcg aaatggaaga gcaccagcaa gtgattgacc ggatctacga
      421 agcgacacga tatctgcctt tggatcgttt gtgcttaagt cctcaatgtg gatttgcttc
      481 aacagaagaa gaaaatgttt tgtttgaaga acaatggaaa aaatttcttt tgtcaaaagc
      541 attgcagaag aagtttgggg aaaatcatta aatcatctag gagagcttga taggaaataa
      601 cactatggta taatcagaat gcttaatact aactactgag ggagccttat gaaaaagaaa
      661 attcttaaat ttatcggatg gttcttcgga atcattcttg ggatcgcgtt tgcaatcttt
      721 cttgccttcc agctttcccc cagacctgga gcattcttga tcaaccatat gttttcaaat
      781 actgttcaaa tcactgataa aaaaacgttc gatcaagcag aaaaaaacgt ggcgaaaaaa
      841 acagatttga cgtatgagtc caagtataaa gagaatactt atgacatcta ctatccaaaa
      901 aacagcaagg ggcctgttcc tgttctattt tgggtacatg gtggaggatt cgtcggcgga
      961 gataaatcgg gtgtcaaaga atttgcgaca aaattagttt cagacgccaa catcgcagtg
     1021 gttgcgatga attatgaatt agcgcctgat tcagaatacc ctaatcaagt tcttcaagtg
     1081 aatgaactga tcaaagattt attagctgaa gaaaaagacg acaaattgct agacatggaa
     1141 caattatttt ttggtggaga tagtgcaggt tcacaaatcg cattgcaata tgcagctata
     1201 caaacgaatg atgcgtatgc taaacaaatg aaaatcaaac agctacttcc aaaagatagt
     1261 ctgaaaggaa ccatttctta ttgcggacct gttgatttga agctaacagc acagcagcat
     1321 tcggatgatc gatttatgaa gtttttcgtc aaaaccgttg cgtggtcgtt gattggaaca
     1381 aaagattgga aaacgagtga gcaattgaaa gaagctagtg tggctgacca tgtttctaag
     1441 gaatttccgc caacgtatat aactgacgga aatgcatact cattccagga gcaaggtcaa
     1501 gcattagaaa atcggttgac agaattaaag gtacccgtgc aatccttgtt ttatacagat
     1561 acaaaaaaag agattaccca tgaataccaa tttgattaca cgctaaaaga atcgcaaaat
     1621 tgttaccagc agacattgga ttttgtgaat aagtataagt aagaggttgt gaaaaagccg
     1681 tttcgttttg agtatgaaga aacgaagcgg cttttcacaa cctctctttc aatacctttt
     1741 tgttcttggg ataaaacttt ccctaacaat caatcgtgca ggataagtca aaatgattgg
     1801 ttcgtcccgt ataccgtcaa ttcgctccaa tgccattcga acagctgctt gcccaattga
     1861 tttcgcattg atttgaacac tggtcaagcc aggggagagg tttgcgattg tctcgatatt
     1921 atcaaagctt gctacaacaa tctcttctcc aatttggata tttttttgtt tcaatgcccg
     1981 atagacacca attgccattg gatcgctccc gacaagaatg gcagtaggaa gaggggattc
     2041 attttctaat agattagtcg caagtacctc accttgtttt tctgtccagc cacctagatg
     2101 ataagacata tatttttcta agtgatgatc gatcataaaa tgctgatagg cacgcatcct
     2161 cttttcattt atagaaatct gcttcccacc gaattcatcc atatcgactt tatatccccc
     2221 gatataggct attcttttat gaccattttc taagaacaat tccagtacgg ttttagtcat
     2281 ccgttcaaga tctgcataca ccatatcgac ctcttgctgg atgtcagggt tatccacgac
     2341 gactatttgc atgttttgtt ttaacaaggc ggtaatcgat tctttcgtaa cagtcccaac
     2401 aacgatcacc gcacctaact gatctagatc ttcccattgt ttaggattat cagatagatt
     2461 atagattcga ttcatcccta aatgcagacg tcgagcttct tcttccatcc ctactcgcaa
     2521 atgtttgtaa tagatatcct gttcttcgct cgctttgccg atcgtagaga tcacaccaat
     2581 cgaaggcatt ctctttttga tatatttacg agtactgatg tcataatcca acgcagcagc
     2641 tgcctctact atccgttgcc gagtagtctg agccacatgg atcgtctgat cgttattcaa
     2701 cacacgggaa actgtagcag gagagacatt tgcctttcgt gcgacatctc taattccaac
     2761 catttttaca cactcctcaa aaaaataaaa aatttttatt gacaaaattg tttagtaaac
     2821 agtatacagg aattataaaa aaaagtaaac ggtttccgtt ttgttgggag tgaaatgatg
     2881 gatattacgc atagaaaaac agataaaaat ttcatcttat ttgatgaaaa gagccgagtc
     2941 ttccatttac gaaatacatt tctttcttat ctgataaaga tagaagaaag caatgtattg
     3001 gcgcatattt attttggcaa accagtcaag cagtacaaag acaataaaaa ttatccccga
     3061 agagatcgtg gattttcagg aaatgttccc ttaaatcctg accggtctct gtcgaaagat
     3121 acactaccgc aagaatactc ttctcatggc agcatggact ttcgaacgcc cgcatcgatc
     3181 attcagcgca agaatggatc agacttactg gatctgagat atgacagcca ttatattaca
     3241 gatgggaagc cagagatcga aggcttgcct caaacttatg tgatggacaa gtcagaggca
     3301 caaacgttgg tgatttcact taaggataga gaaacagcga tttatttcga tttgttctat
     3361 accatattta ctgatagagc agtgatcaca cgatctgtaa agataagaaa tgaaaccgga
     3421 gaaacaatca aactagaaaa agcggctagt ttccagctag actttgccca tactaggcga
     3481 tttgatgaag tcattgcttt gccaggagca catgtcaatg aaagacagat ttcacggcaa
     3541 tctgttttat ctggaacaaa agtatttgaa agccgtcgag gaacgagcag tcaccatatg
     3601 aataacttta ttgctttagt tcatcatcat acgacagaaa atactggaga agcgatcgga
     3661 cttcaatttg tttattccgg caaccattct ttcgaacttg aaaaagatca gatcaatcaa
     3721 ttgagagtcg tcggtgggat caacagccat cgtttttcgt gggaattgaa tgcaggccag
     3781 tcttttcaaa cacctgaaat gatcctttct tactcaagtc agggattgaa caaaatgagt
     3841 cagatccacc atgagttgct acgtgaaaga atcgcaagag gtcgtcatca atttgctgaa
     3901 cggccgattc tggtcaataa ctgggaagcc acttactttg acttcaatag tgaaaaaatc
     3961 aaggcgatca ttgatgaagc aaaggagcta ggcatcgaaa tgttcgtatt agatgatggc
     4021 tggtttggaa aaagagatgc ggacaattct tcattaggag actggttcga gtatgaaggc
     4081 aagttgacaa atggattacg tgaaatagca gattatgctc atagcaaagg attgaaattt
     4141 ggtttatggt ttgaacctga aatgatctcg gttgattctg aactgtatcg aacacatcct
     4201 gattttctta tgcaggagcc aggtagaatg ccttctgctt ccagatcaca acatgtactg
     4261 gattttacaa ggttagatgt tcggcagacg attgagaaac aaatgagaaa gattttagat
     4321 acgattcctc ttgactacat caaatgggat atgaaccgtt cgctttcaga tgtctattcg
     4381 attacccttg acccacagag acaaggagaa gtagcgcatc gttatatgct cgggctttat
     4441 gaactacttg aacatttgac aactgattat ccggaaatct tatgggaagg ctgttctggt
     4501 ggaggtggac ggtttgatgc cgggtttatt tattatatgc cgcagtcatg gacaagtgat
     4561 aacacggatg cagtggagcg tatgaaaatc caatatggaa caagccttgc ttatccgatt
     4621 tcgtccatca cagctcatgt atcagctgta ccaaatcatc agaccgacag atctacttcg
     4681 ttgaaaacaa gaggagaaac agctatgagc gctgtttttg gttatgaact ggatttgaca
     4741 aagctgtctc ctgaagaaaa aaagcaagta aaagaccaaa ttatatccta tcaaacgatt
     4801 cgtccggtga tccagtatgg ccattattat cgtttggcga gtccttttga agaaaatatt
     4861 gccgcatgga tgtttgtgtc tcctaaacaa gatgaagcta ttgtgttttt agggaggata
     4921 ctagcttcag ctcaaccagc gttccatgaa gtatatctga tggggttaga tgatgaggca
     4981 ctttatcagg aacagacctc gaagcggata ttttcggggg ccgaattgat gacagttgga
     5041 ctttacttcc ccgattttca aggtgatttc caaacagaac tgcttcattt caaaaagtta
     5101 tgagagagaa ggaaaaaagt atgaaagcaa atataaaatg gttagatgat ccacaagttt
     5161 ttagagtgaa ccaatcaaat gcacatagcg atcatgtttg ttatgcaaca agggaagaag
     5221 tagaaaccac atcctccctt aaacagtctt taaatggatc atggcgtttt tgttattcgc
     5281 caaatccttc ggtacgacca aaaacatttt ataaaaaaga ttttgatgcc tgttcttttg
     5341 atgaaatcac tgttcctagt catattgaat tagcaaatta tgacaagatc cattacatca
     5401 atacgatgta tccgtgggag ggacatgtat ttcgccgtcc ccctttcacg acaagccctg
     5461 agaaagaggc ggaagggatc ttttcagctg ctaaagacaa tccggttggt tcgtatttga
     5521 cgacttttcg attagaagaa ggtctaaagg gaaaacaaat ctcgattcat tttgctggtg
     5581 tagaacaagc aatgtttatt tggttgaatg gtcattttat cgggtatgcc gaagattcgt
     5641 tcactccgtc tgaatttgat ttaacacctt atttggaaga agaaaatatt ctagctgtgg
     5701 aggtttacaa aagaagtaca gctgcattct tggaagatca ggactttttc cgattttttg
     5761 ggatcttcag agatgtcttc ttagttgctc gaggacaaaa ccatttagaa gatctttgga
     5821 tcaaacctcg cttagatgac aaatgtcaaa atggcaaact tgaagtagat ttgtcttttg
     5881 agcaagtagc caaaaacagt cagctgaatg tagcgatact agatcctgat gggaaggaaa
     5941 tctatcaaca gcaatatccg ttaaaagagc aaatgacgat tcgcatcgat ggatttgaaa
     6001 atgtggcact gtgggggcat tttcagccca atttatataa gcttgaattg gagacgatag
     6061 acgaagaaaa aagagtaacg gagtatattg actattcctt cggttttcgt aaaatcgaaa
     6121 tcaaagataa aatcatctac ttcaatggaa aacggatgat tatcaacggg gtaaatcgac
     6181 atgagtggca tccgaaaaaa ggacgcgcca tcactataga agatatggaa aaagatttgg
     6241 ctatcataaa aaatgcaaag atcaacggcg tacggacatc tcattacccc aaccagatca
     6301 cttggtatta tttatgcgac caagcaggaa tccatgtgat ggcggaaacg aacctcgaat
     6361 cccatggctc atggcaaaaa atgggcgcat ttgagccttc ttacaacgta ccaggtgcag
     6421 tacctcagtg gcaggcggct gttcttgatc gagcaaaaac gaatttcgaa acattaaaaa
     6481 accatccaag tattcttttt tggtctcttg gaaatgaatc ttatgcggaa gaaaacattc
     6541 gacaaatgaa cgattacttc aaaaaagtag accccgatcg acttgtccat tatgaaggga
     6601 attttccaaa tccagcattc gaagattcga tttcagatgt aaaaagctgc atgtatgcgc
     6661 caccagaaga gatcattgac taccttgaaa ataaagcgga aaaaccgttc atcttatgtg
     6721 aatatatgca tgacatgggg aattcgttag gtggaatgga ttcttacatg acgttgcttg
     6781 atcgttatga aatgtaccaa ggaggctata tatgggattt taaagatcag gcgatccaag
     6841 tgactgatcc aatcacaggc agagaagtga tgcgctatgg cggtgacttt gacgataaac
     6901 caagtgacta tgaattctca gggaatggga tcgtttttgc agatggacaa gaaaaacccg
     6961 ccatgcagga ggtaagatat tattatgaaa aatacagtaa ataaaagtca tatggatacg
     7021 gaaaaagttg caatcgtctt cggcgactgt acattaggtg tcaaatcggg gaatacgcat
     7081 tatatttttt cttatacaag aggcggactg gaatcgctca ataaaaacgg aaaagaatgg
     7141 ctataccggg aaacacttcc agttttttgg cgagcaacga ccgataatga cagaggtagc
     7201 ggatttggat ttaaatccgg tatgtggtta ggagccggat tgtatccaaa agtcaaagaa
     7261 atagaagtac tggtggacaa taaaaagatc gatttgccga ttgctccagt aaataatcaa
     7321 tattcaagta atgaatacgc tgaaacggtt gaaatcattt ttacactgga aatcaacaca
     7381 gtaccaaaaa cccaagtgac aatttcctac caaatcgctg gagagggtaa aatgcttgtc
     7441 aatatgcatt attatggaca aaaaggatta ccggaattac ccgcattggg tttaaggttc
     7501 attatgccaa cgaaagcaaa attttttgag tatgaaggcc tatcagggga aacatatccg
     7561 gatcggatgg ctggtggtgt cgaaggtatt tataaagtgg caggactccc cgtttcccca
     7621 taccttgttc cccaagaatg cggcatgcat atggaaacga aatgggtaga actaacaaga
     7681 aatcaaacgt tggataatac ggataaagat caagaagatt tttcgttgcg atttgaacag
     7741 caggatacgc catttgcttt ttccgcttta ccattcaaag cagaagaact ggaacaggca
     7801 acacatatag aagaactacc gccagaaaga cgaacggttc ttacgatttt tgcaaaagta
     7861 agaggagtcg ggggtatcaa tagctgggga gcggatgttg agtcacctta ccgaatcagc
     7921 agcgaagagg accatgaaat cggctttatt attcagtagc aatctttaga ttattatttg
     7981 aaaaacggag tttacaagac aaagctgctt tattctatat gtcatgaaca agagagtaaa
     8041 aaagttctca gatacttttg ttcatgacta ttttcttcaa taaaaccaat tgttattttt
     8101 ctgaaaaaca aagttaacta tcagaaaatt aaaaaaagtt tcataaaaat
//
LOCUS       DAZKCW010000091         8142 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000091 DAZKCW010000000
VERSION     DAZKCW010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8142
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.094"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            165..998
                     /gene="msrA"
                     /locus_tag="ACG84Z_002508"
     CDS             165..998
                     /gene="msrA"
                     /locus_tag="ACG84Z_002508"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFP9163307.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            1078..2067
                     /locus_tag="ACG84Z_002509"
     CDS             1078..2067
                     /locus_tag="ACG84Z_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFP9163308.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            2356..3054
                     /locus_tag="ACG84Z_002510"
     CDS             2356..3054
                     /locus_tag="ACG84Z_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFP9163309.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNAIAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            3204..4520
                     /locus_tag="ACG84Z_002511"
     CDS             3204..4520
                     /locus_tag="ACG84Z_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9163310.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            4537..5952
                     /locus_tag="ACG84Z_002512"
     CDS             4537..5952
                     /locus_tag="ACG84Z_002512"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9163311.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            6416..6736
                     /locus_tag="ACG84Z_002513"
     CDS             6416..6736
                     /locus_tag="ACG84Z_002513"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFP9163312.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            6762..7079
                     /locus_tag="ACG84Z_002514"
     CDS             6762..7079
                     /locus_tag="ACG84Z_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFP9163313.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            7108..>8142
                     /locus_tag="ACG84Z_002515"
     CDS             7108..>8142
                     /locus_tag="ACG84Z_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9163314.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLV"
BASE COUNT         2685 a         1321 c         1725 g         2411 t
ORIGIN      
        1 catttataaa ataaattgat taaaaaggag aatctgtcga taaggattct ctctttttta
       61 tacgaaaaat ctgtaggggg atgaagtaat cgcttatttc ctcactttat gataaattac
      121 agctaaagtc actagcttgt cttcttcgga aaggaggaga atctatggat gaggaacaaa
      181 tattcattca aacactttat aatctgattt tgaatccgaa tacacgagat tgggaacgaa
      241 aagtattgat tcagacaaag aatgacataa gagaaaatat atccgttaaa gaacagttat
      301 caaaactaga agcaacacta cgtccattag ctatccgaat gaatctgacg cctgatgtaa
      361 tggactttta tttattgatt acggaaggat ttgataagga gcaaaaatat gacttttcca
      421 agcatgccat gcaagatgct gactatcaag aacgtgcagt atttgcaggg ggatgtttct
      481 ggtgtatggt cgagccgttt gaatcgaaaa aagggatcct atctgttttg tcaggataca
      541 cgggcggaca tgttgaaaaa ccaaattatg atcaagtaag tggtggttac acaggtcatg
      601 tggaagctgt ggagatcatt tatgacacaa gagaaataag ttatagcgag ttgctgacaa
      661 tctattggca aattactgat cccacagata catttggaca atttcaagat agagggaagc
      721 aatatcgtcc agtgattttt tatcaagtcg aacgacaaaa agaattagcg gaacaatcaa
      781 aacagaaact agacagttca ggaactttcc accaaccaat cgtcacaaaa atcgaaccag
      841 ccggtacgtt ttggccagca gaaaactatc atcagcaatt ttacaaaaaa caaccgaaac
      901 gttataaaaa aatccagcaa gcacgtaatc aatttctgat ctatcaacga gtaaaaaaca
      961 aatggcaaaa aaatatacga aaaaatcatt ttgattaact ccttttcttt aaaatgtagt
     1021 aaactaaaaa tagaaaaaag aaagcgtttt aaaaagattt gatgaggagg agaaaaattg
     1081 tatattgcag atagtgcacg ttatgaaaaa atggaatatc gtaaatccgg tcattcaggt
     1141 ttgaaattac cgattttatc tctcggatta tggcaaaatt ttggtgatta tgatcctatc
     1201 cataatcaaa gagagatttt aagaggcgca ttcgacatgg gaattaccca tttcgacctt
     1261 gcgaataatt atggaggccc tgctggagct gcagagaaaa actttgggcg tatttttaga
     1321 gaagattttc aagcctaccg tgatgaactg attatttcta gcaaagcagg ttatcatatg
     1381 tgggaagggc catatgggga atggggctct cgtaaatcca tcatttcaag ttgtgaccaa
     1441 agtctccaaa gaatggggct agattatgtt gacatcttct atcatcatcg cccagaccct
     1501 gatacacctt tggaagaaac agcagaagct ttgatgcaac ttgtaagaca aggaaaagca
     1561 ttatatattg gtatatccaa ctataatgga gaagatacaa aaaaaatgac tgaaatttta
     1621 aaaagaaagg aagcaccgtt cattattcat cagatgcgct acaatatgtt ttctcgtgca
     1681 ctactagaag acgatctatc tccagtatta gaagaagaag ggctaggggc aatcacgttc
     1741 agtccgcttg ctcaagggtt gctgacaaat cgttatctac atggtattcc tgaagattct
     1801 agagcacatc gtaaggaaat accattcctt tcagaagaac aagttggatc aactctggaa
     1861 aaaatcaaag cactgcaaac aatcgccgta tcacgaggac aatcattagc gcaaatggcc
     1921 cttgcatgga atttgcgaca aaaatctgtt acaagtgtac tggtcggagc aagtcggtta
     1981 agtcagttac aagaaagtgt tcgaatgatg gataatttag atttctcacc agaagaagaa
     2041 ttgagaatcg accaaattct agaatagaaa cgatgtaatc aaacttttta tccatatatt
     2101 aaaaaaaaca aaagatgaca tcaagaatcg aatgaagatc gtctgttatt gaacatcata
     2161 ttttttgtcg ttcaaaataa aaatgatcga aggctaggag tgaattttat cctagtcttt
     2221 tttatggtaa atatcttctt cgtttgtatg tctatgaacg gattaatcaa ttttgtatac
     2281 aaaaaatcat cagatgattc aaacgtgtta taataattac gaaaaaatac atcagatgaa
     2341 aaggaggtat gtggtttgga agaaaataaa accctagtag aagtaactac tgacaagatc
     2401 cttagatatt taaaggaaat gcagttgcaa gtaggagata aactgccgaa tgaatatgaa
     2461 ttgtccgatt atttagaggt ggggcgaagc acggtgcgag aagctgtgcg ggctctagct
     2521 tccaggaata tccttgaagt tcggcaagga gcggggacat ttgtcagtga taagcgaggg
     2581 attgccaatg acccactcgg tttttctttg attgaagatc aggatcggat gatacgagac
     2641 ttatttgaac tgagatattt attggagcct aagatggcag gtttggcagc ggaatatgca
     2701 acgaagaatc aaatcgtcca aatgaaaaaa ttaacgcaaa agattgaaac ttcttttcga
     2761 gaaggcacac aagaacatgt tcaattagac atcgattttc atacgatgat tgcagaagct
     2821 agcggaaacg tagccttgct gcatattatc ccaatcatta atgaatcaat tgctttgttt
     2881 aataaaaatt atgatatcca gcatctgaaa atcgagacga tcgatattca tacagagatc
     2941 gttcaggcca tcgaaaggcg gaatgcaatt gctgcgtttg atgcaatgac tgtccatatg
     3001 gcaataaatc ggagagaatt acagaaaata ataggagaaa aagaaactaa ttgacagttc
     3061 atctgatgta ttttatgata aatacatcag atgaattttt gttttatatt tggtaaaaaa
     3121 gaggagtaaa tagtttctgt tcatcgaaat gtaagcgctg actaatagac aaaaagagat
     3181 gacgtcaagg agaagaagca ggaatgaggg gatctggaat gagttttatg gataaattag
     3241 ccaatgtttt agggaacgtg gcaacgagaa tcaataattt aaggtatatc atggtgataa
     3301 aaaacgcatt tgctgcattg attccggtaa ttattacggg tgcttttggc acattgtttt
     3361 cagcaatggt ctttgactcg gaaaatggct tagcacagat aagtttcttg cgttttttag
     3421 aagaattaaa gcctatcgca tctgccatca gctatgtcac actaagtttc ttgaccatct
     3481 atgctgtttt tctgataggg atcgaattag ccaagctgaa taaagtggat ggtgtattcc
     3541 ctggtatcat cgcagtgatg tcttatttat ctgttaatcc aactgtttat gaattagtga
     3601 atgaaaatca gactgttata gtagaaaacg tattggctaa acaatataca gatacgaaag
     3661 ggttattttt gggaatgttg gtctccatcc tttctattga actttattgc tggttgagga
     3721 aacagaagaa actacagctg agaatgcctg ataccgtgcc aacgaatgtt tctgctagtt
     3781 tttctgcttt attcccgacg attctgactg tatcgggtat cgcggctgcg ggatttatca
     3841 tcaaagaact tacaggaatg tacctttatg atatcattta caatgtcgta caacgcccat
     3901 tagaaggtgt cgtacaaggg ttaccgggta ttttgctatt gatgtttatt gcgcaagtct
     3961 tttgggtgat tggtatccat ggaaatcaaa tggtgaagcc gatacgggaa ccgttgcttt
     4021 tagcggcaat tgctgtaaat acggaagctt ttgaagctgg aaaagaagta ccgaacatta
     4081 ttactatgcc attttgggat atgtatatga gtatgggcgg gtctggagtc acgatcggtt
     4141 tactgattgc agtattgtta gttggaaaac gggaagatat gaaacaaatc accaagttat
     4201 cccttgctcc tgggatcttc aacatcaatg aaccagttat ttttggtatg ccgatcatgc
     4261 tgaatccaat tttagctatt ccgtttatct taacgcctct tatcactgga acgattggtt
     4321 attttgcaac cgctttagga tttgcggcga aagcagttgt aatggtccct tggccaatgc
     4381 cgccgatcgt caatgcttat ctggcaacag caggaaatat cggtgcagtt attacgcaac
     4441 ttgtttgtat tattgtttct attttgatct atctgccatt tgtaaaagta gcaaatcgtg
     4501 tggaaaatga tgggatctaa aaaacaggag gaaatcatga aaattactat tccaaaaaat
     4561 tttattcttg gtgctgcatc ttctgcttgg caaacggaag gttggaaagg aaaaaaagaa
     4621 ggacaggatt cgtttataga tagctggtat aaaaatgaac attttgtttg gcataatggg
     4681 tatggcccag ccgtagcaac taattttatg gaacaatacc agcaggatgt ggatctgatg
     4741 aaatccatcc atctgacaca ttatcggact tctatcaatt gggctcgttt ttttactgat
     4801 tatgagaact gtatagtaga tgaagaatat gctcagcata taagtgaaat gatcgactct
     4861 ttgatcgaag cagacgtaga accgatgatt tgtttggaac attatgaagt cccagctttt
     4921 cttttggaaa aatatgatgg ctggtcttca agaaaagtag ttgattttta tgctaagtat
     4981 gctcaaattg cctttgatcg ttacggtgat agggtaaaaa actggtttac attcaacgaa
     5041 ccaatcgttc cccaaacgcg ttgctatttg gatgctgttc gctggccgca tgaacaaaac
     5101 acaaaaaagt ggatgatgtg gaattatcat aaagttttag caacggctaa agcagtagag
     5161 atttaccgca gcggaaatta tggtggaagg attggctgta ttttaaatcc tgaaatggtc
     5221 tatgctcgat ccaattctcc agaagaccaa aaagctgctt atatgtatga tttgttttat
     5281 aatcgagtat tttttgatcc gatggtaaaa ggatactaca cagaagagtt cctggagttg
     5341 tgtcaaaaac aatcgattta tttcgatcct gcaacagagg atttagaaac gattcagcat
     5401 catacagtag atttccttgg aatcaatcaa tattatccta aacgcgttcg cgcccctcgt
     5461 tatcaatgga atgaagagac acctttccat cctgaacgat attatgaagt ctttgattta
     5521 cctgggaaga aaatgaataa ttccagggga tgggaaatct atccgaaaat catgtatgat
     5581 atagccatgt atctaaaaga aaattatcat aatatccctt ggctgataac agaaaacggt
     5641 atgggaagag aatatgaaga acagtatatg gatgagaaag gaatcgtgca agatgattac
     5701 cgtatcgaat ttatcggaca gcatttgcat tacttgatca aagcaacaga agaaggcgca
     5761 aattgcgaag gctatatgtt atgggcattc actgactgtg tgtcaccaat gaatgcattt
     5821 aagaatcgat atggattagt tcgaatcgaa ttgaacgatg aacgaagcag aacattgaaa
     5881 aaatctgctt cgtggtatca gactttgatt gataagagag aattggattt gcctgacgaa
     5941 atctataaat aaatagaagt tttttgtaga tgttcattgt atttactggt tatttgaaat
     6001 aaaagaggtt gtgaatccag cgttttgagc taatacccag ggtcagctga ttgaacaccg
     6061 tttattgaga ggttgtgaaa aagctgtcct gcatcaagta ataagaatag caaagtaaaa
     6121 acaacatctt atgtttttaa cttggttgga cttattaccg cagatgcaag cttttgaata
     6181 ccgtttattt gaaaaaagtt gtgacaagtt ttgtgtcaca actttttttg tgcacgttaa
     6241 aagaaaaaag gtaataaaaa ttaatttgtg tgtttagtgt gcgctttctt ttttagtgtg
     6301 tatgcaactt ggtatagacc ttaaatgtga tgatatcaac tttttaaagc gcttttaaag
     6361 ttggcacgct acttgcttat atacaagtgt aagtatagaa aggaacgtgt ttaaaatgga
     6421 aaagaaaaca atcatgcttg tatgttcagc tggaatgagt acaagtctcc tagtcacaaa
     6481 aatgcaaaag gcagcagaag caaaaggaat ggaagcagac atctttgctg tatctgcttc
     6541 agatgcggat aatcaactag aatctaaaaa tgtagacgtt ttacttttag gaccgcaagt
     6601 acgctttatg caaaatcaat ttgctgaaaa gctagcacct aaaggcattc ctttagatgt
     6661 aatcaatatg gctgactatg gcatgatgaa tggtgaaaaa gtactcgacc aagcagaaaa
     6721 actaataaac aaataataaa aattatcgga ggatacaata aatggaagat caaaaaaatc
     6781 tagaagccat catgggtctg atcatgtttg gcggaaatgc aaaaagcgat gcaatggaag
     6841 cgattgctgc tgcgaaaaaa ggtgatttca ctttagcaga tgaaaaaatc aaagatgcag
     6901 aggaatcttt agtccaagca catcactctc aaacagagat gctgacacaa gaagcacaag
     6961 gaaatcacgt tgaagtcacg cttttgacgg tccacagtca agatcatctg atgacatcta
     7021 tagcttttac agatttagca aaagagatca ttgatctgta tcgtcgattg aacgcgtaat
     7081 ctacagtaaa gaaaagaggg aagatttatg gataaatttg ttgcatttat ggagaaacat
     7141 tttatacctg tagcatcaaa aattggtgca caacggcatt tagttgcgat tcgggactca
     7201 tttatggtga gtatgccgtt aatgatctta ggagcattag cagtaatgat caataactta
     7261 ccgattcccg ggttccaaga attgatgaac tcaatttttg gtggtgaatc atggaaagga
     7321 ttcggggctg ctgcttggaa cggtacattt gccattcttt ctgtcttgat tgctttcttg
     7381 cttgcttatc atttagctaa cggctaccga aaagacggtg tttccgcagg tgtgatttct
     7441 ttaggctctt tcttcgcttt aggcggagca ttaggtatga gctcaaacgg tttgtttatt
     7501 gctattattg ttgggattat ttcaacagaa atctttgtac gtttaagcgg aaatgaaaaa
     7561 ttgatcatca aaatgcctga tggtgtgcca ccggcagttg caaaagcatt tgcttcatta
     7621 ctaccagcaa tgatcactat ctctgcgttt gctttagttg ctgcaatttt tgctgcattc
     7681 ggtgttgatg atatcgtagg ttctttctat acagtggtcc aagaaccatt tatgggactt
     7741 gcaaactctt atccatctgc cttactgctt gcatttatca caccattctt atggttcttt
     7801 ggtttacacg gagcgaatat ggtcgatcct ttgatgcaaa caatcaatgc gccagccatt
     7861 gaagcaaacg ttaatgcaat cgcagctgga catagcgcac cgtttatcgt gaacaaacct
     7921 ttctttgaca gctttgtcaa cttaggagga acaggtgcaa ctttaggttt actgttagct
     7981 atttatttag taggacgtaa aaacaaacca tatatggttg taacaaactt gtcgattgcg
     8041 ccaggtgtct tcaatattaa tgaaccaacg atgtttgggt tacctatcgt gttgaacccg
     8101 atcatgttca ttccatttat tttgacacca atggtcttag tt
//
LOCUS       DAZKCW010000092         7488 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000092 DAZKCW010000000
VERSION     DAZKCW010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.095"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(94..1392)
                     /gene="eno"
                     /locus_tag="ACG84Z_002516"
     CDS             complement(94..1392)
                     /gene="eno"
                     /locus_tag="ACG84Z_002516"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFP9163315.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(1508..2263)
                     /gene="tpiA"
                     /locus_tag="ACG84Z_002517"
     CDS             complement(1508..2263)
                     /gene="tpiA"
                     /locus_tag="ACG84Z_002517"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFP9163316.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(2367..3557)
                     /gene="pgk"
                     /locus_tag="ACG84Z_002518"
     CDS             complement(2367..3557)
                     /gene="pgk"
                     /locus_tag="ACG84Z_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFP9163317.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(3667..4668)
                     /gene="gap"
                     /locus_tag="ACG84Z_002519"
     CDS             complement(3667..4668)
                     /gene="gap"
                     /locus_tag="ACG84Z_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFP9163318.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(4709..5800)
                     /locus_tag="ACG84Z_002520"
     CDS             complement(4709..5800)
                     /locus_tag="ACG84Z_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFP9163319.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(5949..7283)
                     /gene="rpoN"
                     /locus_tag="ACG84Z_002521"
     CDS             complement(5949..7283)
                     /gene="rpoN"
                     /locus_tag="ACG84Z_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFP9163320.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            7343..7414
                     /locus_tag="ACG84Z_002522"
     tRNA            7343..7414
                     /locus_tag="ACG84Z_002522"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7376..7378,aa:Arg,seq:ccg)
BASE COUNT         1939 a         1581 c         1385 g         2583 t
ORIGIN      
        1 atatttcagc aagtagagag ttcgattact taactaagtg atcatactcg actatctttc
       61 aatagtcgat catgtatctt cattagaaaa gaattatttg ttttttaagt tgtagaaaga
      121 tttcaaacct ttgtattctg caacttcacc aagttggtct tcgatacgta gtaattggtt
      181 gtatttagca atacggtcag tacgtgatag agaaccagtt ttgatttggc cagcgtttgt
      241 tgcaacagcg atatcagaga ttgttgaatc ttctgtttca ccagaacggt gagatacaac
      301 tgctgtgtag ccagcttctt tagccatttc gatagcttcg aaagtttctg ttaatgtacc
      361 gatttggttc actttgataa ggattgagtt agcaattcct ttttcgatac cttcagataa
      421 tttttgagtg tttgttacga acaagtcgtc accaactaat tgaactttgt cgcctaatac
      481 gtcagttaat ttcttgaatc cgtcccagtc gttttcgtct aatccatctt cgattgagat
      541 gattggatat ttagaaacta attcttcgta gaatttgatc atttcgtcag ttgttttttc
      601 gccttcgcct gagtcagcta gtacgtaaac acctttttct ttgtcgtaga attctgaaga
      661 agcagcatcc atagcaagaa caacgtcttt accaggtaca tagccagctt tttcgattgc
      721 ttcgatgatt acttcaaaac cttcttcgtt tgaaccaagg tttggagcaa atccaccttc
      781 gtcaccaaca gaagttgcta atccgcgagc tttcaagatt gaagctaatg cgtggaatac
      841 ttcagcaccc atacgtagag cttctttgaa tgttggagcg ccaacaggca tgatcatgaa
      901 ttcttggaag tcgattgagt tatcagcatg tgatccgccg ttgatgatgt tcatcattgg
      961 tgttggcaat acttttgtgt tgaatccgcc taggtagtgg tataaaggta cttctaggta
     1021 gtcagcagct gcacgtgcaa cagcgataga aacacctaaa atagcgttcg cacctaattt
     1081 acctttgtta ggagttccgt ctaaagcgat catagctttg tcgatagcca tttggtcacg
     1141 aacatcgtag ccaatgattg cttcagcaat gatgttgttt acgttgtcga cagctttagt
     1201 tacaccttta ccgccataac gagctttgtc tccgtcacgt aattcaactg cttcgtattc
     1261 accagttgaa gcacctgaag gaaccattcc gcggccaaaa gctccgcttt ctgtgtatac
     1321 ttctacttcg attgttgggt taccacgtga gtctaagatc tcgcgagcgt aaacatcagt
     1381 aataattgac atgttttgtc tctcctttga gtttgttttt tcctaaggga tttccctcat
     1441 atacgatttt agttaatttt gctcattagt gcaaacattt cttgcatttt tcgcaaattt
     1501 tcaacaatta ttttacagcg tctaacaatg acaagaatga atctgcttgc aagcttgcgc
     1561 caccgactaa agcaccgtca acattttctt ttgccatgta ttcagcaata ttttctggtt
     1621 ttacagaacc gccgtattgg atacgaactg cttctgatac ttcttttcca taaagttttt
     1681 caactgtttg acgtacaact ccacaaattt cgtcagcgat ttgtgcgtca gctgatttac
     1741 cagtaccgat tgcccagatt ggttcataag caataaccat gtttgacacc tgttcagctg
     1801 aaagatcagc taaaccagct gtaatttgtc cttcgatcca ttcagcagtt ttgcctgctt
     1861 cataggtttc taaagattcg ccgcagcata ggattggtgt cataccattt gcaaagatag
     1921 ctttcgcttt tttattgatg tcttcgtctg tttcatggaa atattcacga cgttctgaat
     1981 gtccgatgat cacataatga acacctagat cagcaagagc tgctggtgaa gtttcaccag
     2041 tgaacgcacc tgagttttcc cagtagcagt tttgtgctga gatttttagt tctgtacctt
     2101 cagctgatgt cattaattct tgtaagaata atgcaggaga tccgatgact gaatcaactt
     2161 tgtcatttga agggattttg ttttttactg cttcagcaaa ttcttttgct tctgatgcag
     2221 ttttgttcat tttccagtta cctgcgataa taggtttacg cattgaggaa cacactcctt
     2281 aatttattga aaaatggcta gggagtcatg aaaactccct tcaccttttg ttcgattact
     2341 cgtcagaatt gagcaaactt ggtcgtttat ttatcgttga ttgctgctag tcctggtaat
     2401 tctttacctt caagcaattc caagcttgcg ccgccacctg ttgagatgtg tgtgaatttg
     2461 tcagcaaatc ctaattgttc tgctgctgcg gctgagtctc cgccaccgat gattgttgtt
     2521 gcgccttcta agttagcgat tgcttcacaa acaccgattg tacctttagc aaagttactc
     2581 atttcaaata cacccatagg tccgttccaa acaactgttt ttgcaccttg taatgtatca
     2641 gcaaataatt ttactgatgc tgggccgatg tctaaagcca tcaaaccatc aggaatgtct
     2701 ccttcgatta cttgtgtttc aacatcattt gaaaattctg gtgcacagac attgtcgatt
     2761 ggcaagacaa gtttgtcgcc tgctttttcg attaattctt ttgctagttc cactttatca
     2821 gcttctacta gagagttacc gatcttgatt ccttttgctt cgtagaatgt gtaagtcatt
     2881 ccgccaccga tcaagatttt atctgcttta ggaatcaagt tttcgattac gccgatttta
     2941 tcagaaactt ttgcgccacc aaggattgca atcattggtc gttttggttc ttctactgct
     3001 tcaccgatga acttgatttc tttttccatc aagaatccag caactgttgg gataccagtt
     3061 gaagcgatac ctacgttaga agcatgtgca cggtgagctg taccgaaagc atcgttaaca
     3121 aatacatcgc ctaatgaagc ccagtattta cctagttctg tatcattttt gctttctttt
     3181 ttaccgtcaa tatcttcaaa tcgtgtattt tcgaatacga caacgtcgcc gtcattcatg
     3241 ttgcggattg cttcttctaa ttgttctccg cgagtttcag gtacgaatgt tacttcttta
     3301 cctaataatt cgcctagacg ttttgcaact ggagctaaag attttccttc tttatcttct
     3361 tctgttttta cacgtccaag gtgagagaaa aggattgctt ttccgccttg ttctagaacg
     3421 tagttgattg ttggcaatgc tgctttgata cgagtgtcgt cagtgatcac gccgtctttc
     3481 aaaggaacgt tgaagtcaac acggacaaga acttttttgt cttttaaatc gatatctttc
     3541 actgttttct tagccatttt atttcctcct gaataaactt attatcaaaa aaagcggaag
     3601 aagcgcgatt gcttccccgc ttttaaatgt acatgtctat aatttacact tgtacgtttg
     3661 tctatcttat aagttagcga agtattctaa agtacgtact aattgtgcag tgtatgacat
     3721 ttcgttgtcg taccaagcaa cagttttaac taattgtttg tcgccaactg tcattacttt
     3781 agtttgtgta gcatcaaata atgaaccgta agtcatacca acgatatctg aagaaacgat
     3841 ttcgtctgtg ttgtatccgt aagattcgtt tgaagcttct ttcattgctg cattgatttc
     3901 gtcaacagtt acttcttttt caagaactgt tactaattct gttaatgaac ctgttggtac
     3961 aggaacacgt tgagcagctc cgtctaattt accgttcaat tcgggaatta ctaaaccgat
     4021 agctttagca gcacctgttg agttaggaac gatgtttgca gcagcagcgc gtgcacggcg
     4081 gaagtcacct ttaggatgag gtccgtctag agtcatttgg tcacctgtgt aagcgtggat
     4141 agttgtcatt aatccttcaa caacaccaaa tttgtcgttc aatgttttag ccataggagc
     4201 taaacagtta gtagtacatg aagcacctga gataactgtt tctttaccag ttaatgtttc
     4261 gtggtttgtg ttataaacga ttgttggaac atcgtttccg ccaggagcag agataacaac
     4321 gcgtttagca ccagctgtta aatgtttttc agctgctgat ttagaagtga agaaaccagt
     4381 acattctaga acgatatcta cgcctagttc gccccatggt aattcttctg ggttgcggtt
     4441 agctaatact ttaacttctt ttccgtttac gttgaatgaa ccttcatgaa cttcaactgt
     4501 tccgttgaaa cgtccttgag ttgtgtcgta ttttaacaag tgtgccaaca ttttagcatc
     4561 tgtcaagtcg ttgattgcta ctacttcgat tccatctaca tcttggatac gacggaatgc
     4621 tagacgtcca atacgtccaa aaccattaat acctacttta actgtcattt aagatttcct
     4681 ccttatgaaa atcaaaaaaa tatttatttt aaagggttac cccttttaaa atctcatttg
     4741 cagcagcttc atcagtgatg agccacgttt gttttggtgc atttttcata taagctcgaa
     4801 ttgctttagc ttttgatttt ccgcccgcga ttgccatgat gatcgggact ttttccaaat
     4861 cttgcaattc tatgccgatt ctagggacct tataaacgac ttcacctttt tcattgaaaa
     4921 agtagccaaa agattccgca acagcatttg cttgtttcag catgactaat tctttttcag
     4981 tcatcttacg acgtgctgcc atgtgtaatg cacgcccaat actatgaata acacaattcg
     5041 cttcactaat caagtttaag acttcttgga tagatggctc attgagtaaa gaattgtaag
     5101 ttgccagact taattgttcc ggaacataaa gtgcgcggtg gttaccgttt gctttagcag
     5161 ccattcttgc actgacagaa tttgcctgta cagttatcgc ttcaccaatc ccgcctcttg
     5221 cagggacaaa caggttatgc cgtttcttat tttccagatt agacaattgt tcggctacca
     5281 cagccatagt agttcctccc atcacagcga tgatattctc gccttctgga agtagtcggt
     5341 ctaaggcttc gctcagcgct tcgccgaatg catcagccac tttggtctgc tcttcgctgt
     5401 ttcctgaaac aacgatacag cgttggttac caaaatattc tgccaactgt tgttcggttt
     5461 gatgcgtacc taaaagctga tccatgaagt tttcaaggct ttgataaact tcttcgccct
     5521 tagttgtcag cgtcataccg ctttttgagg tgtcgatcaa attcagattt ttcaaaaggt
     5581 ctgtttctgt tcgtaagact cgttctgtga tccccatact ttccgataaa cttcgacgcc
     5641 caatcggctg catccaatag atatttcgta aaattttata gcgttcttgc aacacttcga
     5701 taatatctgg tgcaacagat tcaatcattt ttatttcatc cagcatagcg atctccttag
     5761 ttggacactt tacgtccaat gtagacttaa aacgacccat atacgataaa aaaagaaatt
     5821 aactattcga atttcacatc aataaaggga aatctcaacc tcacgactgt aagtctaaca
     5881 gttttgctct cgtttttcaa ctaaaaagac tagaaaaagt gaaatacttt ttctagtctt
     5941 ttgactgatt agttatcata acgttttctt tttgatgaac tcgggattcc taataaatca
     6001 cgatattttg ctactgttcg tcttgagatc gctatctcat cttttttcag caattcaacc
     6061 aatttctggt cagacaacgg cttgtttttg tcttcttgat cgactaattc ctgcagcttt
     6121 ttcttcgctg tatctgctga aaggtcttct gtctgttctg tactattcgt aggaattcgt
     6181 gtagtgaaaa atttttttaa ttcaaataca ccgaagtctg tttccaaata tttcccgttg
     6241 actgcacgac tgaccgtgga ttcatgcaca tctatctcag ttgcaacttc ctttaacgta
     6301 agaggcttga ttggacgttc cttgtcgata aagaaagctt tttgccggga aacaatgact
     6361 tgagcaaccc gcaaaattgt atccccacgt tgtaggatcg ttttcttcaa ccattcgaat
     6421 tcctgtttcc gttcttttaa ataattttca gtttctttat ctgcttgttg tgacatttgt
     6481 ttgaagtaac tctcttgaaa gcgtatattt ggctgatttt ttcggtttga gataacttgt
     6541 acatttttat cgtcgtccac taatacccgg acatcaggaa taatgtacaa ttcgctgcta
     6601 cggtcgaaaa tccggccagg gcttggactc aacgtttgta aatagtcgaa tatctgctga
     6661 acagcatgta gatcaacaga aaaacgttgt gcgatttctt tccattttcg ctccaccagt
     6721 tcctcaaaac attcttccaa cacgatataa gctaattccg gcgcataatc atctcgttct
     6781 gtttgaagca tgagacattc ttgcaaacta cgtgcaccta ctccagctgg ttctaattgc
     6841 tgaatcagag tcaacgcatc gagcatttgg ataggcgtag ctccaatctc ttttccggct
     6901 tcttctaaac taatcgtcaa aaatccgttc aaatcgatgt attctacaag ataaagaacg
     6961 attttcctca aaaaagtatc tcggtaattc aaatggactt gttcgatcaa tgaatcaaat
     7021 aaagaccctt ttgtatcagg aatctgattt aggtaatttg tctcttctcc ttcataagaa
     7081 gatgaagaag cttttatgta atctggctgc cattccggct caacaacttc caccaatgga
     7141 ttttccattg cttgattctc aacgaatgcc aacagctcct cactgttata ttgtaaaact
     7201 tggatggact gttgcaactg ttgcgtcatg gctagtttct gtgtctgctg ctgtttttgt
     7261 gaaaaatttt gctcaaattt catttttttg tccaatcccc ttgtaatttt ttatctgttt
     7321 agttacaatt atcccagtgc ttgcgtcctt agtgtagtgg atatcacgta agattccggt
     7381 tcttgagacg ggggttcgat tccctcagga cgcgttctac tgctatttta gcataattta
     7441 cgaatagttg cttctttatt tttaagtgaa aactgtccgc caaagaaa
//
LOCUS       DAZKCW010000093         7463 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000093 DAZKCW010000000
VERSION     DAZKCW010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.096"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(147..1067)
                     /locus_tag="ACG84Z_002523"
     CDS             complement(147..1067)
                     /locus_tag="ACG84Z_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFP9163321.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            1193..2245
                     /locus_tag="ACG84Z_002524"
     CDS             1193..2245
                     /locus_tag="ACG84Z_002524"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFP9163322.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(2355..3110)
                     /gene="fabI"
                     /locus_tag="ACG84Z_002525"
     CDS             complement(2355..3110)
                     /gene="fabI"
                     /locus_tag="ACG84Z_002525"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFP9163323.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            3330..3770
                     /gene="fabZ"
                     /locus_tag="ACG84Z_002526"
     CDS             3330..3770
                     /gene="fabZ"
                     /locus_tag="ACG84Z_002526"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFP9163324.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(3885..4646)
                     /locus_tag="ACG84Z_002527"
     CDS             complement(3885..4646)
                     /locus_tag="ACG84Z_002527"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9163325.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            4835..5929
                     /locus_tag="ACG84Z_002528"
     CDS             4835..5929
                     /locus_tag="ACG84Z_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFP9163326.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(6015..6974)
                     /locus_tag="ACG84Z_002529"
     CDS             complement(6015..6974)
                     /locus_tag="ACG84Z_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HFP9163327.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         2354 a         1325 c         1457 g         2327 t
ORIGIN      
        1 tttcaaattt ttgtgaattt cagcttattt ccgaaggagt tgcttctgct tccgccgttt
       61 atacgtgttt agagcgtggg acaaaagtgt tctttacttt tgtcccacgc tctttttagt
      121 gagattcgtt gcatcgtttg tccaaattat tttccgacag caattggact gttcggaatc
      181 gtgaaaccag aagctgtcaa ttctttgaca taggagctca agaactcttc ttttaaggca
      241 tattgttttc cgttcaatgc gtagcagacc gtacgaatcg caaaattgct gtttccaaga
      301 tccactaatc caaagataga aggttcagtt tggagctctt cttggtattt ttcagctaat
      361 gtacgattta ctcgatcaat gatctcatag attttgtcat atccttcttc aggaacaatc
      421 cgaatatcta aaagtacttg catatttgca cgagagagat tgctgatcgt ggtgatgttt
      481 cgattcggga tgaaatggac agtaccatcc gttgctttca gctgaagggt acggatacca
      541 acagatacga cggttccttc aatcgttaag tttgctagct tgatgtagtc cccaacatcc
      601 atctgttgtt ccatgataat aaaaaatccg gtaataacat cactcatgaa cccttgggca
      661 ccaagaccga ttgccacacc tgcaattccg gcaccagcca aaagtgatcc gatcggcaca
      721 ccgatagcag ataaaattgc atagataaaa aagaaaccaa gggtataatg aaaaatagta
      781 tttaaaagac tatgtaaagt ctttaagcgg ctctcgttta gaatggcttt tttagaatac
      841 tgattaaaag acttatcaat cagatatttt cccacacggt gaagaatcca aaaaaggacg
      901 atcaaaaaaa tcagatataa acttttttgg ataaaggcag ccaaaatggc gtcccaatca
      961 atcccgtccc aaaaccgctg aaacgcattt actttgctga cagcttgatc tgtcaatgtc
     1021 tcgccagaag agtctgtcgt accggcagtt gctaataatg aaaacataaa atcctctttt
     1081 ctaaaatttg attctttctg tattgtacca agaagttttc aaaaaaggaa atagcaaaaa
     1141 taactataat gaaggaaaaa agctgaaaat aaaatgacaa ataatatgga taatgataaa
     1201 atgtggagaa aataacgaag gtggtaagta tatgcaaatc gattggaaca atctaggttt
     1261 ttcttatatc aaaactcctt ggcgttttat tgccaaatgg aaagacggac aatgggaaga
     1321 aggagaattg acagaagata attacctgac gattcatgaa ggctctccag cgcttcatta
     1381 tggtcagcaa tgttttgaag gtctaaaagc ttatcgtcga aaagacggca aggtcaatct
     1441 ctttcgacct gaacaaaata gtcgacggat gaatcaaagt gctagacgat tgctgatgcc
     1501 aatggtccct gaaaagatgt tcgttgatgc tgtcaagcaa gtggtaaaag caaatgaaga
     1561 ttttgtgccg ccctatggaa caggcgctac attatacttg cgccctttac tgattggggt
     1621 cggtgaaaac attggtgtcc atccagctcc agaatattta tttgtcgtct tctgtacgcc
     1681 agtaggagcg tatttcaaag gtggactaaa accaacgaat tttattgtat ctgattacga
     1741 tcgtgctgct cctaagggga ctggtgcagc aaaagtcggc ggaaattacg cagcgagttt
     1801 acttccagga acagaagcaa aagaactgga ttactcagat tgtgtttatc ttgatccagc
     1861 cacacatacg aaaatcgaag aagtaggtgc agcaaatttc tttggaatta caaaagacgg
     1921 aaaattcatc actccgcaat cgccctctat cttaccaagt atcacgaaat attccttgtt
     1981 gcagttagct gaagaacgac taggactgca agcaattgaa ggagatattt tcattgatga
     2041 tctagatcaa tttgcagaag ctggtgcatg tggtacagcg gctgttattt ctccaatcgg
     2101 tgggatttat cacaataaca atcttcatgt attttatagt gaaacggaag taggaccagt
     2161 aacaaaacgg ttgtatgatg aattgacagg tattcaattt ggagacatag aagcaccaga
     2221 aggctggatt gaagtcgtgg aataatttca aagtaatgag ttgaaaaaaa cgtaaaaaga
     2281 aaaaatcagg aagagacttt aaaaagtttt ttcctgattt ttatatgttt tactttaaag
     2341 aatgcaacaa aagtttatga aagatggaca cctttgtcaa cgtagataat atcaccgatg
     2401 attccgctgg aaagtgggct gattaagaaa gcacaagcat taccgacttc ttcgatcgtc
     2461 acaccttgct gatcaggcgt acgagattca gataactgga tcagtttttg atagtcttta
     2521 acacctgtga cagctaatgt tttgattgcc ccagctgaga ttccattgac ccgaattcct
     2581 ttaggcgaga actcagctgc caaataacgg atagcagctt caagagaagc tttcgcaata
     2641 cccatcatgt tataattcgg gattgcgcgt tctgaaccta gataagtcat gctaacgatc
     2701 ccgctgtttg gtgcaagaaa cggttgtgcg tattttgata cagcaattaa agagtagctg
     2761 ctgatatctt gagctaattg atagccgtct ctggaaatat cagacacatt tccggacaat
     2821 tcttctttgt tggcgtaagc aactgcatgg acaaggccgt ggatctcccc agcatattca
     2881 ccgatggcat tcattgcttt ttcgatgctt tcgtcgctag aaacatcaca ttctacagtg
     2941 aatgcttctt cgccgaccaa tttgactaat gattttttca ttcgttcatt ttggtaagta
     3001 tagataattt ctgccccttg tttcaacatt gcttcagcac aaccccaagc aatgcttttt
     3061 ttgttagcga cgcccataat gacgattttt tttccttcta gaaatgacat aatgactctc
     3121 ctttgtttct gataaaaatt tgatagtcgt aaaaaaatag agaataatag ctaaaataac
     3181 ttcttgattt cttaattatt agtcaaaatg ttttgattgt caaactattt tttcttaaat
     3241 taaaaaaaga ttgctaaata tttaggaata tgatactttg atagtcaaag taatgaaaat
     3301 ggcaattgcc tgaaagaagg agtttaatta tgtcttacgt attatctgct actgaagtaa
     3361 tggaattgat tcctaatcgt tatcctattt gttatattga ttatgtagat actttagaac
     3421 caggaaaaaa gatcgttgcg acaaaaaatg taacaatcaa tgaagatttt ttccaaggtc
     3481 actttcctga caatccagtg atgccgggtg cgttgattct agaaacactg gcacaagcag
     3541 gttcgatact tatcctaaaa tcagaagagt ttctaggaaa aagagcttat atcggtggga
     3601 tcaataaggc caaattccgt caaaaagttg ttccaggaga tgtgctgaaa tgtcattttg
     3661 aaatcaccaa aatgaaggga tcagtcggta cagcgttatc tgcagcatat gtagatgata
     3721 aaaaagtctg tgagtgcgag ttcacgttca tcgtcaacca aaatgcttga ctataaaacc
     3781 tgatatagca aaacaaaagg aagcttactt gctttttatg taaaaagaag acgcctgaat
     3841 cctagcatac gttgtcatct atgcaggatt cagacgttat ttttttattt ttgttttgct
     3901 tcttgcagta tattgatttt atcgattttt acttcttctt ttggtttgtc tgaactatct
     3961 gtttcgatat ttgcaatagc atccacgaca tccattcctt caatcacttg gccgaagaca
     4021 gtataatggc catctagtga aggataaccg ccgtttttat aagcgtcgat gattgcttga
     4081 ggatagtcgt cttttaaaag accatcatgc atatcatctg tattttgaac gataaagaac
     4141 tggctgccgt tactgttagg atcttgtgag cgagccatag ataacgcacc tcttatatta
     4201 taaaggtggt tgttgatctc tgtttcaaat ccttctcccc aaatgctttc ccctccagtg
     4261 ccatcgcctt taggatcgcc accttggatc atgaaatctt tgatgacgcg atggaaagtc
     4321 agtccgttgt agtaaccgtc ttttgcatgt gtcataaagt tttcaaccgc ttttggtgcg
     4381 tgttcgggaa ataatttgat tttgattgtg cctttattcg tcaccatttc gaccagatct
     4441 tcattttcgg cgacatcttt cgtcaattgt ggtaattcca atgcgttcaa atcgacgcta
     4501 ctggcagtcg tgctttccgc agtagatgta ctttttgaac tttctgtaga cgaactagaa
     4561 gaagtcgtgt tgtttgcaga acaaccagca gcaaacagca atgctgctgc taaactaata
     4621 cttaaaataa ctttattttt cttcataact gttcctttcc aatttactat tttgttatct
     4681 ttaatgataa caaaatagag ggaaaatacc tacttaaatt attggaattt atcatttatt
     4741 ttaaaagaaa aagaaaaggt gtagaccatt tactttgtgt ttgctataat gtaagtggat
     4801 acaaaaacga aaagatgcag gaggaaatgg taatatggga aaattaggaa tctcgattta
     4861 tccagaacgg tcaacatttg aaaaggacaa agcgtacttg gatttagctc ataagtatgg
     4921 gtataaacgg gtttttacca gtttgctgca gatcaatgat gataaagaaa aagttctttc
     4981 agaatttaaa gaagtagttg attacgcgaa tagcctaggc atggaagtaa tggttgatat
     5041 caatccagcg ttatttgaac agttggagat ttcttacgat gacttatctt ttttccataa
     5101 gatgggtgcc tacggggtcc gcttagatat cggattcaca ggagcagaag aagcaaaaat
     5161 gacgcgcaat ccttttggta tcaaaatcga gatcaatatg agttcgggca cgaattacgt
     5221 tgacaacatc atgagttatt cgccaaacac ggataattta ttaggttctc ataattttta
     5281 tcctcatcga tactctggtt taggatacga acactttgtt ttttgttcag aaaaattcag
     5341 aaaatataat ttgaatacga tggcattcgt caattcgcaa tctgctgagt ttggcccttg
     5401 gcctacgcaa gatggcttgt gcacgctgga agaccaccga gatcttgaaa ttgcgacaca
     5461 agtgaagcat ttaatcctta caggattgat tgatgatatt tctattggaa atgcgtacgc
     5521 aagtgaagaa gaattgaaag aaatggcaga agcatttaac gcggattatc caacattgaa
     5581 agtagatacg gaagaaggta ttacagaaaa cgaacgaatc tgcttgtttg ataaccttca
     5641 tagttatcga ggggatcgct cagaatatat ccttcgttca acgatgactc gtgtatacta
     5701 caaagataaa gatttcccgc ctcataatac gcgagatatg catcatgggg atgtactgat
     5761 tgacaatgaa gggtacggtc aatacaaagg agaaacacaa atcgccttga aggatatgaa
     5821 aaacgacgga cgtgtcaatg ttgtaggaag aatctccgat gacgaattat tcctccttga
     5881 ctttttgaaa ccatggtcaa gctttaaatt aattgaaaat aaaaaataga taattagtta
     5941 ttgcagaaat aatccgctag aaatagccag ttatttctgc ttttttattt tgttttttta
     6001 taggttatga tttgtcaaat taagctagaa taaaatgctt cttgtacata gctcaaaaat
     6061 atttcgattg gtgttctgta attcaatgat tttcttggaa tatgattacg ttgattgctg
     6121 acactggaaa taaatgtctg attcactttt ctaaaatcca ttgatttcgg cagtccatta
     6181 cgacgcagaa tcccgttaga attctcgttt aatgggcgtt gagaaggtgt tccagggtcc
     6241 gcaaaatata tatcaatatc atgttggtta ctaatggctt tccagttaga aaattctttt
     6301 ccacagtcaa acgtaataga tttaaagaag tttttaggga agcgagaaaa ccattgatta
     6361 agggcagttt caatatctaa tgccttacgg ccgttgggtt taatcgtgat aatgacttta
     6421 gataatcttt caactaaagt aatgacggca cttttatgat gaatgccaac gatcgtatca
     6481 ccttcaaggt gaccaaactc agaattgaaa tcaggataat tatcaggtcg atcatggatt
     6541 gagcgctgat actgttgttt tccccgtttt tcctgatggc cattgggttt tcttttacct
     6601 ttcatcggta gtgtgtcaat atcaaatatt cctttagaaa ataaacgata aagtgttctc
     6661 ataccgcatg aaacaggcct ttcttttcgc ccgataatga cgtcaggcgt ccaaccaaga
     6721 gtgactttct ctttaatgta atctacttca tgagcaggta attgaatgac ttttctacca
     6781 cattttttct tattttcttt atactggtgc caataatcaa gagcagtctt gccttgcttg
     6841 aacttattga ctacattata aatagtttgt atagcacgtc ccattcggtt agcgatttca
     6901 accggcttat tatgttgaag ataatatgat tctatcattg tcagttcgtc tatggtaaga
     6961 tgtttgtagg tcatttatgg ttacactcct ttgttttctt tcgtcggaaa tacaatttga
     7021 gtgtaccata aatgcctttt tatttttcta acttaatttt acaattcgcg atatattaaa
     7081 caacgttgtc gcgcttcatt gaaacatttt atgaaaattc caaaaaagag ttgacacatg
     7141 tttttagacg tgataagata actaagtcgt taaaaagaac cacttgcgaa gcttgattct
     7201 atcgaaaaaa aacttcaaaa aagttcttga caaataacaa acgataagtt atgataaatg
     7261 agttgctgaa agatttcgaa aaacgaaatc gaaaaaaact tttaaaaaag agttgacaat
     7321 cgcttgtctc tctgatatga tataaaagtt gctacggcag ccaaaaacga atcgggaaac
     7381 actcccgatg aagtagatct ttgaaaactg aacaaagtaa gacaaaccaa atgtgtaggg
     7441 cgtcttgatt caattcaaga caa
//
LOCUS       DAZKCW010000094         7223 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000094 DAZKCW010000000
VERSION     DAZKCW010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7223
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.097"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1251)
                     /locus_tag="ACG84Z_002530"
     CDS             complement(<1..1251)
                     /locus_tag="ACG84Z_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFP9163328.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
     gene            1570..2295
                     /locus_tag="ACG84Z_002531"
     CDS             1570..2295
                     /locus_tag="ACG84Z_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163329.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            2285..2794
                     /locus_tag="ACG84Z_002532"
     CDS             2285..2794
                     /locus_tag="ACG84Z_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163330.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(2864..4312)
                     /locus_tag="ACG84Z_002533"
     CDS             complement(2864..4312)
                     /locus_tag="ACG84Z_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFP9163331.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4312..5028)
                     /locus_tag="ACG84Z_002534"
     CDS             complement(4312..5028)
                     /locus_tag="ACG84Z_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFP9163332.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(5009..5359)
                     /locus_tag="ACG84Z_002535"
     CDS             complement(5009..5359)
                     /locus_tag="ACG84Z_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFP9163333.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            5503..6276
                     /locus_tag="ACG84Z_002536"
     CDS             5503..6276
                     /locus_tag="ACG84Z_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFP9163334.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            6447..6813
                     /gene="ssrA"
                     /locus_tag="ACG84Z_002537"
     tmRNA           6447..6813
                     /gene="ssrA"
                     /locus_tag="ACG84Z_002537"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(7118..>7223)
                     /locus_tag="ACG84Z_002538"
     CDS             complement(7118..>7223)
                     /locus_tag="ACG84Z_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFP9163335.1"
                     /translation="SVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT         2112 a         1403 c         1287 g         2421 t
ORIGIN      
        1 tttgaaattg taaaagttgc gaaagccgta cgcattgcgt tttaatactt tgatgtggtt
       61 gtttaagcat tccaatggtc cgtttgaata gctgtagtga agcgcatttt ggatctgtgg
      121 cagaaacttt ttaaacgttc gtaaagtggt tgtataggtt tctggcagac cgctaatgtc
      181 tctagttaaa caatcctcaa atagtgactg atctcttttc tttaccgcat aaagaatgtc
      241 ttggtataac tgatagcctt ggcgtaagtt gggacaagca gctaacagtc gatcggcaat
      301 ctcactttca gtcaaataat ctttaaaact ggcacgccaa acccgttttt catagtttaa
      361 ctttgcttct tctttttgta ggagtttcca atagcgcttc aattttttcc ctaaccctcg
      421 ttgagagtgg gaatttcctt taagtcgtac cgtggtttct ttcactcgat gattcaagaa
      481 agttctgcca atatgttgga cgatgtggaa acgatcgatg atcaactgag cattcgggaa
      541 aagctttttc accaacgaaa cataaggcgc atacatatca ataacaatca attgaacggc
      601 ttcacgagtc gctaatgaaa accgagaaaa atagcgttct aaataaggca agcgtcgatt
      661 ttcgacaata tccaataatg catggctttg tccgtccatc atgataaaac tcattgcact
      721 ggcaacactt cgaaccgatt tgaattcatc aaagcataag acctttggca aagtctgttt
      781 gaaaggattc aatgggcggt agaatcgctt catgacacga tagaccgaag aagtggaaat
      841 atttttctga cgagcgattt ccgtcatgga agtattctct tttaagcgag caatgacaga
      901 ccaacgaact ttttgactaa tgaaacagtg tttttcagca acagaggtat ccgctacgaa
      961 tgttctttgg caagacttac atttaaatcg ttgtttcttc agctccagat aagtgcgata
     1021 ctcagacaca tcattcagta acaaccgaac ggttgtcgtc ccccaacgaa tgatcctaga
     1081 ggggacgaca caaagacaat gggaacactc ttctggcttg tacagaagag ttcctttgta
     1141 aatcaagcaa atttgccctt tgtatttttc tttagttaaa caattttcct cgaaatagat
     1201 atttaggtct agaatattta gggtatcttt gataagctga gtatgagaca tcttgaatcc
     1261 tcctatgaat tggtagccaa attaattcta aaggatttca gggtgtcttt tctatatttt
     1321 tttatacaaa aaagatgttg gtgaagttca ccaacatcaa aaagtataga gcccaaaatt
     1381 attgtcgctg ctcctctttt cgaataaaca gtgttcaaaa gcttgcatct acggtaatag
     1441 aatagggcag cttcttcaca acctcttgct ttttacaaaa tattttctgg ttttaattcg
     1501 tgatttcact aaaggaattt catactttat tcatattcat tttctatact ttttatagag
     1561 gtgaaaagta tgaaaataat ccgctatgct actgctcgat taatttatta caaaaagcag
     1621 acaatactct attgtttatt ttcaagcttt tctgcttttt tattgatagc atgcctgact
     1681 ctttaccatt cgcaatcggc tttagccaat caagtccaag atcggctttc atttattggc
     1741 gcttctgcat ctacagagct tcttccggct ttagaattag ctagccgatt ttatataaaa
     1801 ggcatattca gtttattttt tctatttgcc ttccttttta tctttttctt ttactattca
     1861 gtcaggcaaa acaagcagga attgatcaat tggcgcctga ctggtctttc taaaaccaaa
     1921 ttattccttt ttattttctg gcagctgttc tttcctctct ttctttgttg tatcttggtt
     1981 ttattgtgga tcgtcagctt ccagtcagtt tatgaagcgc ttcttcaaag gatcaatttt
     2041 cttgtcttaa agactactga actgccagat atccgtgata tcttgacttc ggtaagcgga
     2101 cttacaattc cgatggatca acagactttt tttaccatcg atttccaaaa tgatcttttt
     2161 ttcacagata tacttaaggg atttgcccaa actcttattg ggctcagtgg atgctgtctc
     2221 attcttagtc tattcccttt cacttttttt atccatcatt tgcaaagtag gaggcctgga
     2281 cgtaatgaaa cctgaatatt tgattcatgc tgaacacttg accgttattt tgtgtcctct
     2341 cgaaaaacag cataaaatat tggagcactt gaaaaaagag gttcttgttg caaaactgga
     2401 taattttgcg atcatccaaa aaaattggcc gatgtttcct tatctgaatc ttaaagacca
     2461 tgtcctgttg gatgtaccgg aaaaagaaat caaacaagat cgtttggcct atcaagaaaa
     2521 acttgatatc tctccttcct tgcttaattg tgcggcagct gagttgacgt cttttgaaaa
     2581 agtaaagctg caattacttc atgccttgct ttccaagcga aacaatattg ttattgaaga
     2641 tacatttgat gaacttagtg tattggagat ccaagagcta ctccacttgc tttcttattt
     2701 agctcatgaa gaaaatcaag gtatcttact ctttactcat gatgctacta ttgctcaaag
     2761 tccttatatt gatcgtttag agcccgcggg ctaaatcaat cattttatag taaaaacaag
     2821 cggtatagaa gatcgattca tgatctttta taccgcttgt tttttactct tttttgattt
     2881 ctacgtcagg caaacgaaca gcgaattttg ttccttttcc tagttcgctt tctacttcta
     2941 attttccttt atgcaagcgt acaagttgct gcacgattgg taaacctaat cctgattcac
     3001 catattttgt attttttctt gaaggatcta ctttataata acgatcccag atacttttca
     3061 tttgttgttc agacattcca attcccgtat cttcaatcgt gatgatcgtt tcaagatagc
     3121 ctttttctaa agtaatcgtg atttggccgt tttcagtaaa ctgtatcgcg ttttgaataa
     3181 tattgaccat gatttggaca aatcggtcat aatcagcgta aacatcaata tcatcaacgg
     3241 ctttcaatgt caatgtatct cctgctgctt ctgctttagc ttctaactgt gcaacaatat
     3301 ttttcaatgt ttctgttcca ttgaattttt taatgaccat actgatttga ttcgtacgga
     3361 ttttttcata atccaagttt tcattcacca aacggatcag acgctctgtt tcatttttca
     3421 tcaatttaat cgcgttttct cgctgatttt cagggattgc attgtattct aacccttcca
     3481 gaagtccgtt gattgtcgta agaggtgttc tcatctcgtg agaagcatct gccataaatt
     3541 gtcttcgacg attttcttgt tcttcaattt ctgcttgaga ttctttcaat gaattcgtca
     3601 ttttattgaa atcatctgct aactcatcaa attcatcttt gtcatgtacg gggagctgta
     3661 catcaaaatt accattcgtc acttctttcg tcgcattcct taaccgattg atacgcttaa
     3721 cttggaatgc tgcaaaagca tagctggcaa taactgcaac gatactggaa aaaataaatc
     3781 ctttgaacag gttcagtgta attggacgaa cgctgttatc gatatttcgc gcaggttgac
     3841 taactacaag tgctccatag aattcatgat tcaaattaaa tggcacaagt gcgtaagagg
     3901 tcgcctgtgc ttgtcctaaa atatttttat tcgatgtgaa tttttcttga cgtccattcc
     3961 tcagattttt ccattgatca gctgttaagg taaaattcag taaagctgta ttagtcggat
     4021 aaatgacacg ttcgttttta tcgataaata taaagttcac attttgttct gtcagtactt
     4081 gctctgtcag cagcaatgca ttttgaaacg cctgatcttg actaaactgc gggagcgtat
     4141 cggcataggt ttgcgttgtc ttttcaactg attcagcata tccaaacagt tgctggtaat
     4201 tgttttcttc aatcgtttgt tttgtcagtt gtgtaaaaga aactccaacg atcaataaga
     4261 tcaacgcgac cattccgcaa aaagctaaga gttgctgata caaataacgc attaggcaac
     4321 accagaatca tcgaatttgt agccgactcc ccaaacagtt tggatgactt gtggtccgac
     4381 cttttcgatt ttttgtcgta atttcttgat atgggcgtcc actgtccgtt catcaccaaa
     4441 gtactgataa tcccagacta attcaagcaa ctgctcccga gagaatactt gacgtggttt
     4501 ttttgctaaa gtaaacaata gatcgaactc tttaggcgtc agtccttcaa ttggccggtt
     4561 gtccagatac gcttctcgtg ttttcgtatt catcttgaaa tgactagtct cgatatcaaa
     4621 atgatcatct gaaactgctg cttcttctct tgcttctgcc aactcactac ggcgatgcaa
     4681 agctttcatt cgagcaataa gcgtcagagg actgaaaggt tttgtgacat aatcatctgc
     4741 ccccatctct aagccgatca cctgatcgct ttcagaatct ctagctgtca gcatgataat
     4801 cggcacagta cttgaaactt tgcggatctc tcttcctact agcataccgt ccagtgtggg
     4861 caaattcagg tctagtgtaa tcatatccca atgttgtggg ttttctaaaa aggcatcgag
     4921 cccttctttt ccatcatact tgaaagttgc ttcccaacct tcatttaaga aaaacatctg
     4981 catcatttca gaaacagatt gattatcttc aatcattaaa atattcatta tcgttccctc
     5041 cagtttccag gtcatatttc tgtaatttct tttctgtcat aataaaaata ggcataattg
     5101 gaaatactag cagaagcatt tcaatcagaa aataattcgt atgcccagat gtctttaaat
     5161 aatagccgat caatgccatc agtaagccca taagaaaaaa ccagtttccg cttgtctttt
     5221 gagccagccg ccaatgagcg tctgtttttg cggcaagagg cgaatgatac ccataaaaag
     5281 gcagatttcc ttttgagggc agaatccgaa aaagactgcc aattattaag aataagatac
     5341 caatactgaa aaaaatcatt ctttccctcc taaattctct tcttatagta tactctaaat
     5401 tgttgactga accaatatgt tcaggaattc ttcacgaaag gtttgtcttt tgttcattct
     5461 ttgttaagat aaacttattc caataaaaaa ggagttttat ttgtgtcaaa ttatcgtgca
     5521 atcactttct ttgatcttga tggaacatta ctagatgcga aatcaaaaat cacacccgaa
     5581 gtggcaaaag ctatgaacgc attaaaagaa aacaatgttc tccccgtcat cgctacagga
     5641 cgtacagaag cagaaatcca ctctatcatg gaagatgcgg gcattacttc tgcggtcacc
     5701 atgaatggtt ctttcattcg agtagacggc gaagaaatct attctcaaac attttcttca
     5761 gaagaatgtc aaaaaatgta tgatcatgta cagttgaacg gtcatgaact ttcttactat
     5821 aacgatcaga aaatctggtg taccggtcat agccaaacaa tgatcaatgc ttacgacttc
     5881 attcattcag atgttccgga aattgatcct ttaggcttta aagaaaacac agtaaatatg
     5941 ttgctgatct tatctcaatc aggtgacgaa tactatcacg aacattttcc tgagctaact
     6001 ttttatcgga atggtcctta ctcgatcgat acagtgaaga aaggaatctc aaaaggggca
     6061 ggtgtcaaac gtctgcaaaa agaacttcag ctggaaaaag ttcctacttt tggatttggc
     6121 gatggtccga atgattttgc cttgttggaa gcttgcgaca acaaaatcgc tatggacaac
     6181 gcctatgacg gattaaaaga actttctacc tttatcacaa agaaaaatac agaaggcgga
     6241 attgtccacg cattgaagta ttttgatctg atttaagatc tttttttgaa gctacctctt
     6301 ttcttaagaa aatcgcttat tttttcttaa gaaaggggca gttattatat aaataatggg
     6361 atatgattcg cttttttatt gaatttatcc caatatatgc tatactaatt ttgtatgaaa
     6421 aatacacgta acccttgtta gctaacgggg acgttacgga ttcgacaggc acagtcgagc
     6481 ttgaattgcg tttcgtaggt tacgtctacg taaaaacgtt acagttaaat ataactgcta
     6541 aaaacgaaaa caactcttac gctttagctg cctaaaaaca gttagcgtag atcctctcgg
     6601 catcgcccat gtgctcgagt aagggtccta actttagtgg gatacgtttc aactttccgt
     6661 ctgtaagttg aaaaagagaa catcagacta gcgatacaga atgcctgtca ctcggcaagc
     6721 tgtaaagtga atccttaaat gagttgacta tgaacgtaga tttttaagtg gcgatgtgtt
     6781 tggacgcggg ttcgactccc gccgtctcca tatatgtatg gttgagacag ataaacatgt
     6841 atgaaaaacg ttgttaaatc aacgtttttt tattttggtc aaggagagaa aagtagagaa
     6901 atacaaaatt ttttgcattg attttgcatt caaaaaaaca ttcaaacatt tagaaatccc
     6961 caatacgtat tcaggaaaat ctattttaag gtttacaaaa agaacttttg ttcgtacact
     7021 ctttttgagg tgaactttta tgctgatgga aggaaaaaca caattatggt ttaagcatgt
     7081 tccttcaaat aagttttttt aattattatt tgtcaaatta agcgagacaa aactttccat
     7141 ttacgtaact caaaaaaact tctaatggtg tttggtaatt tagtgatttt ctagggatat
     7201 ggtttctttt ggacgcaacg gat
//
LOCUS       DAZKCW010000095         7169 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000095 DAZKCW010000000
VERSION     DAZKCW010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.098"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(63..515)
                     /locus_tag="ACG84Z_002539"
     CDS             complement(63..515)
                     /locus_tag="ACG84Z_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFP9163336.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            665..1615
                     /locus_tag="ACG84Z_002540"
     CDS             665..1615
                     /locus_tag="ACG84Z_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFP9163337.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            1608..2567
                     /locus_tag="ACG84Z_002541"
     CDS             1608..2567
                     /locus_tag="ACG84Z_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFP9163338.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            2564..3319
                     /locus_tag="ACG84Z_002542"
     CDS             2564..3319
                     /locus_tag="ACG84Z_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163339.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            3342..4295
                     /locus_tag="ACG84Z_002543"
     CDS             3342..4295
                     /locus_tag="ACG84Z_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFP9163340.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(4939..5235)
                     /locus_tag="ACG84Z_002544"
     CDS             complement(4939..5235)
                     /locus_tag="ACG84Z_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFP9163341.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            5590..5946
                     /locus_tag="ACG84Z_002545"
     CDS             5590..5946
                     /locus_tag="ACG84Z_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFP9163342.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            5956..6855
                     /locus_tag="ACG84Z_002546"
     CDS             5956..6855
                     /locus_tag="ACG84Z_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFP9163343.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT         2202 a         1214 c         1434 g         2319 t
ORIGIN      
        1 tatttgatgt caatctgatc aaaagctttt tttgcatgta aaaatttatg tgttttttcg
       61 ttttaaaata aacgatccca gaagcttttt ttcttttttg gtttttcttt ttcagctggc
      121 gaagagtttt cttctgggta ttttttttcg atatcaatca caggttcatt tactgcttct
      181 tttgctgtta agagcaatcc gaattcctca ggatttgcag tgacgtaatc gttgactaca
      241 gtgaaacggc tattgttttt cgttgctagc tggatatatt ggttttggac agaaaggggt
      301 agagccccat tcaagagtat ggaagcatct ggatgttttt tgagttcttt taaaaagttt
      361 tctttgtttt ttggttggat catttcagca acagtcatac taagatagca gcgttccctg
      421 aatgtcccta aatatttatg ctgttcttca gggttcacta aaggtgtacc ataaagtccc
      481 ttatccaaat ggctttttac atcatcttgt gccataaaaa ataccctcct tcttctcttt
      541 gtctttctta cgattatagc atattcccaa taatacctaa aacatatgaa aaagcggttg
      601 cttttgttca acgattcact taaaataaga atgaaaatca ttctcaatta gaaaggtgga
      661 ttggatgcgc tacggacgac tagtagcatt attagttatt ttaagtagta tttcattgtt
      721 catcggagta tcgaatgtac aattgtcaga actgctccag ttagatgggc aaagcttaca
      781 aatcttgcta gtgactcgtt tgccacgaac gatttgtttg atccttgtgg gagcgaccag
      841 tagtatttgt gggttgatca tgcaacattt gacccaaaat aaatttgttt caccaacgac
      901 tgcgggcacg atggatagtg cgcgtttagg tattttagtg gctatgattt tcctacctgg
      961 tgcatccttg attgtccgat ccttgacagc attttgcttt gcttttgcag gaacattgct
     1021 ttttttatcc cttacgcgat tgttcctcca gaaaaatcaa ttgatgcttc cgttgattgg
     1081 agtcatgtta gggaatatca ttggttcagt tgctactttt tttgcttatc aattccagtt
     1141 ggtacaaaat atgacttcat ggcttcaagg gaattttgcg actgtgatac gaggaaatta
     1201 tgagttattg tatgctgttg ttccattgtt gctcttggtt tggctatttg cttaccgatt
     1261 tacgatcatt ggtctgggcg aatcgtttgc agtaaatctg ggaatagatt accagaagat
     1321 gcagttttta ggcattggct tagtatcatt ggctagtgca gtcatgttga tcatggtagg
     1381 aagcattcct tttatcggag tgatcattcc gaatcttgtc tctagaatat atggagatca
     1441 agtgcacaaa acaattggcg taactgcttt agcaggtagt ttgttcttag tattttgcga
     1501 tcttgtcgct cgcgtgttga tttttcctta tgaaatacca gtcagtgtga tcgttggaat
     1561 catcggtggg gctatcttcc tttatcttct gataagggga cgacgatatg cttaaaaaaa
     1621 agccatctat ttttattggt atgcttgttc ttgttttatt tgttacagga atgtacttga
     1681 cgatccatac atatggaaac tggcattttg catgtgcatt gaggagtaag aaaatttttg
     1741 catttatcct tgtctcgcta gctgtcagca gtgccacaat cagctttcag acaattacgc
     1801 ataaccagtt tttgactcct tcagtattgg gacttgagtc gttatatgtc cttgtccaaa
     1861 cggtcctttt cttctttatc ggaggagtga cgatgcttca gcagacaggt acagtttttt
     1921 tcttattgaa cgttgggctg atggtcgggc tgagtctatt gttatttttc tttcttttga
     1981 aaaaaatgag agcgaatctt tttttattac tgatgtcagg gatgatttta ggtacgcttt
     2041 ttggtagtgt cagtaccttt ttacaagtca tcatggatcc gaatgaatat gatttgcttc
     2101 aaggcagatt atttgcaagc tttggcaata tccagagtca gtatcttttg cctgcttctt
     2161 tgatcattat cggctgctgg tacctgttat ttcgatatcg acatgtgcta gacgttttcc
     2221 atctcggaaa tgaacaagca gtaaacctcg ggatagacac agatcgtttt gaatttttga
     2281 ttttatgttg tgtcagtctt ttgacaggga catcaacggc tcttgtgggt ccagttactt
     2341 ttttagggtt tattgtcgca aatatcagtt atcgtgtctt ttctacttat cgtcatggtc
     2401 agctatttat cggaagcttt ctggtagcta tgctgtttct gacaggagga cagctcgcag
     2461 tagagcagat tttcggctgg aatacaacag tgagtgtcgt cgttgaattt gtcggaggaa
     2521 tttattttgt cacaaaattg attcgcgaaa ggaagagtat cctatgattg atttacaaaa
     2581 ggtcaataaa ctgtaccatg gaaaatcagt ggttaaagat gtacagttaa cgattcctga
     2641 aaagaagttg actgctttta tcggtccaaa tggtgctgga aagtcaacgg tgttgtcgat
     2701 gatcagtcgt ttgataccaa aagatacagg tgaaatctat ttagaccata acgaagtaaa
     2761 ggcttggaaa tccaatgaat tagccaaaaa attatcgatc ctacgacaat cgaatgaaat
     2821 aaatgtccaa atcaccgtga aagaattagt agaatttgga cgatttcctt atacgaaagg
     2881 aaaattgacg acaaaagacg aggaaatcgt tcaggaatca ctggaacaca ttgggttaga
     2941 agaaatagcg gatcaatcga ttgacactct ttcaggcggt caactccaac gtgcgtatat
     3001 tgcaatggtg ctagcgcaag acacggatta tattttactg gatgaacctt tgaacaatct
     3061 agatatgaat tttgcggttc aaatcatgca gattttaaaa aatttagtac aagaaatcgg
     3121 gaaaacaatt gttattgttc ttcatgatat caactttgct gcaagttatg cagacgaaat
     3181 tgttgcaatg aaagatggac agttatttac gcaaggaacg acccaagaaa tgataaaaaa
     3241 agatgtattg gatgaattat acgaaatgga catacggatt tgtgagattg aaggccgcag
     3301 attctgtctt tatttctaaa actaacatta ggagagaaga gatgaaaaaa ttagtagtag
     3361 gtatcttgat tctagcatca tttggtttag cagcatgtgg aaatagcaac aacaccagtc
     3421 aggcagacac aaaaaaaagc agcacacaaa ctgaaactac attgacgata acagatagta
     3481 atggagacca aatcgaggtg ccaaataatc cagaaaaagt cgtcgtattc gacaatggtt
     3541 ctttagatac gatggatgct cttggtgttg gagataaggt agttggagca gctacaagca
     3601 gccttcctga gtatctttca tcctataaaa aagtagaatc agcaggtgga ataaaagaac
     3661 cagacttaga aaaaattaat cagcttcagc cagatctaat catcatttct ggccgacaaa
     3721 gagattttca aaaagatcta agtcaaattg ctccgaccat tttcctttct ttagatgcga
     3781 aaaatccatg ggaatctttc cagcaaaatg tcactgcttt aggggagatc tttggtaagc
     3841 aagaagaagc taaaactcaa ttagaggaat tatctagtgc aatcgatcag acgaaaaaga
     3901 aagcagaagc tactgacaaa aaagcactag tcacacttgt gaatgaaggg caattatcag
     3961 cctacggatc tggttctaga ttcggtttca tccatgattt atttggcttt gaacaagcag
     4021 atgatcaaat cgaagcatcc actcacggtc aaagtgtttc ttatgaatat gtgctggaaa
     4081 aaaatccgga tatcttattt gtagtagaca gaacaaaagc tattggtgga gacgacagca
     4141 aagatgatat ttctgccaat gaactggtag cacaaacgaa tgctggtaaa aatcagcaga
     4201 tcatctccct tgaaccagat gtctggtatt taagcggggg cggtttagaa tcaatgaaac
     4261 tgatgatcga agatgtgaat caagcattta aatagcataa ataacagagg attaaactct
     4321 catactatgt aacaataatg tttcttacat tcttaaatag caagagccta tcctcaaaga
     4381 agttatcaaa aaccatccgt aaaatcgtat tgatgatttt acggatggtt tttatttatt
     4441 tgagaaatct tttttcaacg tgaattcatt atctacatca tacgggttga ttctagaatg
     4501 gggagtggca aaaaatagtg tgatccattt tttcagcatc aagatcgcct cctttgattt
     4561 gaatcaaagg tacaaagcga aacttagata aaacttaaat ttagatattt ttattttgta
     4621 ccgatctctt ctttaaacga tgttccatct gctgcttctc ggcaataagt ccactagact
     4681 agaaaatatg agaagctatt ttctgtccag cgttcttatt actcaaaaca aatcgcagtt
     4741 gtcacaatct cttctaaacg atgttccatc tgctgcttct cggcaataag cccactagac
     4801 tagaaaatat gagaagctat tttctgtcca gcgttcttat tactcaaagc aaatcgcagt
     4861 tgtcacaatc tcttctaaac aatgttcaat cagctgacct tcggtattag ctcaaagcac
     4921 tgatttcaca acctctattt aggcatgtgt ctcagcaagc ggttgatagt tgatgatctg
     4981 catttttcga taaaaatcgg cgggaagctt actccaccgt tttagtaatt gatagaaata
     5041 actctcttct gctttgattt tatactcgct taatatcaat ccaaaactat tcgttttttt
     5101 tgaagctaat tttttataaa tatccaatgc tttggtttta tcttcattga caaagagtgt
     5161 ttttacttca atataagaac cctcgatatt ttgtgtttct tcgataaaat agatgttttt
     5221 tatatattcc ttcatagtga ttcctccaaa gaagtctttt atttgataag tttactctac
     5281 cgaagagttg ttaataatcc gtgaacaaaa agtaattctt tttccaatag ttgttaaagg
     5341 ttttttattt tttatagtat tttttgttat ttaagaaagg aataaggtta aacaaataac
     5401 aggttgcttt ttgggtcttt ttccgttcaa gaaactgaac gaagaaaagg gaaagttgtc
     5461 tcttttgtga taagagaaat cataataaac gaatgactta ctttccaata aattgagaac
     5521 agtcagaacc agacaaatta gttgcatctg atgaataaag tgattattct atgacatgag
     5581 gtgatacaga tgaaattaga agtgacaaaa gaagcacaag aagtattgaa gaataaatta
     5641 gaagcagacg atcaactttt attagatatc gaaaacggtg acggtccatt tgcagaaagc
     5701 caagtcagtt gccaattgga tacggcattt cgattgatca ttgtcaaaaa agatacacaa
     5761 acagatctaa gtctttattc tgtagtggct gatacaccag ttggaccaat caaaatcaaa
     5821 gacagtgcaa tactttacat ggatgatcca tccacacttg ctttagaacc aacttataat
     5881 agtttacaat taaaaggacc aagcggcttg agaaaaggca acttgcaagt tgttcgaaaa
     5941 gactagaggg ataaaatggg aaaattggcg atcatcagcg acctacatgt ggacatcaat
     6001 aaattcggcg aatcagagct gatgcagctt tggcaagttt tgcaaaagca caagatcact
     6061 cggcttcatc tagccggaga tacggctaat aaagtagacc gttgcctagc tgttgtcgaa
     6121 tttttcgtca ataaaggatt atctacgaca tttcatttcg gcaatcacga gttggcagat
     6181 gtgcccaatg aacagatgat ggaccatttt ccagacccac attttttaaa tgaacggtat
     6241 attgctttaa atgagcagac cgttctttta gggatgaatg gctggtacga ctatcagttt
     6301 tccgaattga aagattacga ggcaatcgta cgaatgaagc gtttgtattg gtatgatcgg
     6361 ttcatccagc gtgggaaaac agatctcgag gtcaatgcag aaatgcttgc agctgcaaaa
     6421 aatttgctag accagctgga agcaaaaaaa cttgaggtga ttttatccac tcatttcgtt
     6481 cctaaacggg catttatcat gtatcaatct gctccttatg agcgttggaa caaattaaat
     6541 gcatttttag gatcagaatc attcggagaa ttacttgacc gttattcaaa tatcaaacaa
     6601 gtagtttttg gccatacgca tcgtcgcttt gaagataaat ccatcggtca cacgatttac
     6661 agctgcagac cttttggtta ttattatgaa tggcagctga cccgagattt tgtcttgaaa
     6721 gaacagttgc tagacagcta tgatcctatg aaattacgtg tcctcttgcg tgcccatcac
     6781 ccagcttttc aggcctatca aacacaacat ttgcaagagg aatttgaaca agcgatgaca
     6841 atcgttccgt attgagacag cattagtaat gtgtaaaaga aaataccttg taaaacataa
     6901 ggataagtaa gagcagtaga tccatttatc gtggatatgc tgcttttttt gcggaaaata
     6961 atcagcgaat gtttatttga tcggatgatt tgtaactcgc agagtactag atgcaagcgt
     7021 gtattctttt tttgaacgat aatcacaaaa aaaaatataa tatacatttt ttatttaatt
     7081 ataattaata ttgattgaag tctaggcagt caagtcgaga gtgtaaaata ttttgtgtaa
     7141 atgaaaaaat ccatacaaaa aaggaagtc
//
LOCUS       DAZKCW010000096         6989 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000096 DAZKCW010000000
VERSION     DAZKCW010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.099"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            127..579
                     /locus_tag="ACG84Z_002547"
     CDS             127..579
                     /locus_tag="ACG84Z_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163344.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="ACG84Z_002548"
     CDS             593..1282
                     /locus_tag="ACG84Z_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163345.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="ACG84Z_002549"
     CDS             1407..3758
                     /locus_tag="ACG84Z_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFP9163346.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="ACG84Z_002550"
     CDS             3838..4233
                     /locus_tag="ACG84Z_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163347.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4558..5175
                     /locus_tag="ACG84Z_002551"
     CDS             4558..5175
                     /locus_tag="ACG84Z_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9163348.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5216..5515
                     /locus_tag="ACG84Z_002552"
     CDS             5216..5515
                     /locus_tag="ACG84Z_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFP9163349.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5549..5716
                     /locus_tag="ACG84Z_002553"
     CDS             5549..5716
                     /locus_tag="ACG84Z_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFP9163350.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKKYFYCP
                     KCHRRYGVHGT"
     gene            complement(5761..6231)
                     /locus_tag="ACG84Z_002554"
     CDS             complement(5761..6231)
                     /locus_tag="ACG84Z_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9163351.1"
                     /translation="MEFREGAFDFQTSQQNPSLDRLGRDYEDIKNTVAFMKQKKVALK
                     ILDAQFLDFNTGNELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKG
                     RPIEYSINSTDPQKRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            complement(6237..6917)
                     /locus_tag="ACG84Z_002555"
     CDS             complement(6237..6917)
                     /locus_tag="ACG84Z_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HFP9163352.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGITA"
BASE COUNT         2354 a         1016 c         1374 g         2245 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg
     4381 aataaatata atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat
     4441 gccttgattt tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt
     4501 ctgatttaat ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg
     4561 agaaaatttt tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt
     4621 tccgcgaagg aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa
     4681 gattttaaac gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc
     4741 tatctacaat cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga
     4801 gaattaacta aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact
     4861 gctagttaca agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta
     4921 ctcagctata tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta
     4981 gaagctgcga aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa
     5041 tttcctgcga tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat
     5101 caattgggca tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg
     5161 caccactttt cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga
     5221 cttaacgaat caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc
     5281 catcggtttg gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa
     5341 tttcctggtt tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa
     5401 ggaacaaacc gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt
     5461 cgaattttat gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt
     5521 agtaaaattt acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat
     5581 tgaaataact agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt
     5641 agcaaaaagt gtttatcaaa aaaaatactt ttactgtcct aaatgccatc gccgatacgg
     5701 ggtacatgga acatagaaac gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt
     5761 ctacaaatca ttcgctttct ttattttata aatagttggt cgagagatcc cgttttcttt
     5821 tgcaatctct gcaactggaa tgccttgctt taacatgtcc accacggttt taaaaactaa
     5881 gcgtttttgc ggatctgttg agttaataga atactcgatt ggtcgtccct tatatcggcc
     5941 ggctttttga gccaataata ctccttgccg ctgacgttca cgaattttct cacgctcgtt
     6001 ttgtgcaata taacttagca gtgataaaaa catatcgaac atagcggtat ccaggagttc
     6061 atttccagta ttaaaatcta aaaactgtgc atctaatatt tttaacgcta cttttttctg
     6121 tttcataaaa gcaactgtat tttttatatc ttcataatct cttcctaaac gatctagtga
     6181 tgggttctgt tgcgaagttt gaaaatcaaa cgcgccctct ctgaactcca aatatcttag
     6241 gctgttattc ccattaatac cttgatttca gtagacaccg aaaagccgaa gagcgttcca
     6301 tttcttcggt tctttttata tattcctcga atggtctcca tgcccttaat cgtggaagag
     6361 gctgtacgga gactttgata aaatttattt cgtcgtttaa taggtcgatg gtcttgttct
     6421 attaaattgt taagatactt cacagttcgg tgctctgtct tagtatataa acccacactc
     6481 tgtaactttc taaaggcgga gccaagagaa ggtgctttat cggtcacaat tgctttcggc
     6541 tcaccaaact gtttatggag tcgttttaag aaagcatagg ctgcttgcgt atcccgtttc
     6601 tttcgtaacc agatatctaa ggttaagccg tccgcatcaa ttgcacgata aagataatgc
     6661 caacgtccct taattttgat ataggtttcg tccattttcc atgaatagaa ggattgtcta
     6721 tttttcttct tccaaagata atagaggact ttgctgtact cttgcaccca acgataaatc
     6781 gtagtatgac aaacatttat tccacgatca tataacaatt cctgaacttc acgatagctt
     6841 agattgtaac gcaggtagta accaacagcg acaataatga cgtctttttt gaattgtttg
     6901 cctttaaaat gattcattac tctgtcctct ctgtcttttt tctcaatttt acactaaaat
     6961 agattttttg gaaaactttg caacagaac
//
LOCUS       DAZKCW010000097         6910 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000097 DAZKCW010000000
VERSION     DAZKCW010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.100"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            173..976
                     /locus_tag="ACG84Z_002556"
     CDS             173..976
                     /locus_tag="ACG84Z_002556"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9163353.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGKRIVPEYNNAIRVFSKRRNPFNHMTVMFD
                     KKAILEVGNYQPLSGFEDYYLWARLLKAGYKGYNIQETLVYARTGKDMYARRGGMKYL
                     GSGLMGRYRIWKDGLGSVKDFIIVSCGHIFISLLPNQLRGKFYQTQLRK"
     gene            1009..1863
                     /locus_tag="ACG84Z_002557"
     CDS             1009..1863
                     /locus_tag="ACG84Z_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HFP9163354.1"
                     /translation="MKKIQQITLKMSQEIVDFCLKNQLLCYFCGGGAIGTVREQGFIP
                     WDDDLDFFMPREDYEKFYQLWVNSEKSKKYPIQKASKNYNDHNSFTTIRDADTTFIKT
                     YQRDLDIVHGITIDIFPLDVAPVSKFSRKIQKLWALVYALFCSQVVPEKHGGIMATGS
                     KILLSIFRSPRTRYKIWSFAEKQMTKYNNEPTGYVTELCVGPKYMGNVYPAKDFESAV
                     WVPFEDTEMPVPVGYDNYLSQVFGDYMQLPPEKDQVSHHEAVYIDPEHPYTMYKGKYY
                     LTKGAEKK"
     gene            1860..2561
                     /locus_tag="ACG84Z_002558"
     CDS             1860..2561
                     /locus_tag="ACG84Z_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HFP9163355.1"
                     /translation="MITAIIIAGGVGKRMGQDIPKQFITIEGKPIIIYTLESFQHHPQ
                     VDRILVVCKSGWEETMWAYIKEFNISKVKWVITGGSKGQESINNGVQFLKDYSEDDDT
                     IIIHDGIRPLVDELVLSDVIVKCKEFGNGVTSLPYNEQIFIKKTEETTEQYVDRNTLR
                     RVSTPQAYQYGKLRAAYDRAVKEDIGMTDSSYTNTMMVDLGETLYFAAGSDKNIKLTT
                     TDDLELFKAYLKMKD"
     gene            2569..3636
                     /locus_tag="ACG84Z_002559"
     CDS             2569..3636
                     /locus_tag="ACG84Z_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFP9163356.1"
                     /translation="MMTLIKQPMYQEDLAKVINHTPKIKQLHGKSVLMIGASGMIGSF
                     LIDTLMAANEQLGIKIKVYAMGRNRQKLEKRFASYLELDTFEIVEGDVTEPLPKEIQA
                     DYLIHGASNTHPKAYATDPIGTIMTNLAGTEQVLKHAVATQPVRVLFLSTVEIYGENR
                     GDIEKFTEDYCGYIDCNTLRAGYPEGKRVSESLCQAYIAKHDLDIVIPRLCRTFGPTM
                     LLSDTKASSQFILNAVEQKDIVLKSEGNQYFSYVYVGDAVSAILHLLLEGEKGEAYNV
                     SSENFDLRLKELAQQLADISGKQVIFELPDEIEQKGFSKASTAVLENKKIKETGWKPI
                     FPLNESLVHTVELVKGEKYNV"
     gene            3629..4594
                     /locus_tag="ACG84Z_002560"
     CDS             3629..4594
                     /locus_tag="ACG84Z_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9163357.1"
                     /translation="MCEISIIVPVYKVEKYLRKCVDSILAQTFTDFEVILVDDGSPDN
                     SGKICDEYAEKDNRVRVIHKENGGLSSARNAGIDVARGKYLGFVDSDDYIDEDMYEIL
                     YENLKIHDADISSVELIPFYGDRYKKANKEKKVIILNKKEAIKSVLEGTQFYAYAWNK
                     LYRKELFKDNRYLDGKTFEDAYIIIDLLFQTEKIVVSNEEKYFYLQRNDSIMGKSFSM
                     NNFDVIEAWQYNKEKILDAFPDLHDSYYRRLCWAYFYVLDKMVLSSSYQQIPRKKTVI
                     EFLKKNRNFILTYKGFTKSRKIAIIALSFRVDWYRKLVEQKNKKN"
     gene            4639..5613
                     /locus_tag="ACG84Z_002561"
     CDS             4639..5613
                     /locus_tag="ACG84Z_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9163358.1"
                     /translation="MCRISIIVPVYNVEKYLKKCVDSILGQTFTDFELLLIDDGSTDN
                     SGSICDELAKTDNRIKVIHKENGGLSDARNIGIEVAKGDFIGFIDSDDYIDEDMYAFL
                     YNNILKYDAELSMCGIYDVHKNKEIKKLTPFSQLVTKSEAIELVLDGKLVVANAVSKL
                     YKKELFENVRYPKGKIAEDAAVILKIINQCNKIHVDTSQKYYYYHRGDSITSKKFTKK
                     DFDIIDVWNENEKWIIKNYPQMYDKVHTRVCWAYFVVLDKLVLTEEKGLYQEKKQVRE
                     YLIDNFFFIIKNKRLTFQRKISMLLLTFGIAAYKIPVKYQYKKVKAVN"
     gene            5636..>6910
                     /locus_tag="ACG84Z_002562"
     CDS             5636..>6910
                     /locus_tag="ACG84Z_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFP9163359.1"
                     /translation="MKKSRLEYSLINSSISMFIYILRIVIQFVGRSFFIYFLGAKYLG
                     LNGLFTNILSFLSLAELGIGSSIIYSLYKPLAQKDESKVKALMNLYKKTYEFIGIFIG
                     IVGVLIIPLLPLFIKNSTDIPHMYRYYVLFLLNSVLSYFFTYKRSLAIADQKNYLVAI
                     NDFAFLFFMNIVQVIALYFYSNFTLFLIVQILFTLFSNINISRTVDKRYSYLKEKDVV
                     SLDKQTKDEVKKNVIGNMSSKIGGVIVMGTDNILISTFVNLTAVGIYSNYSLIVTSVQ
                     NLCKQITNSITASVGNFAVSNKKKDSFELFKKHFFINHSLIFFSSILLLTLMNPFISL
                     WVGAKYMLPMSTTILIVLNYSVQVYRNTSFVFIESFGLYWSQRKKPIIEAGVNLLLSL
                     LLLIVFDMGINGVLIGTIGSSLGFVIWYEAFII"
BASE COUNT         2516 a          896 c         1283 g         2215 t
ORIGIN      
        1 cttcaaacaa tcaaaatctt atttgataag atgtcatctc aaggactaga tgaagatgaa
       61 aatattagtt cattagcaga aatcgacttt tcacaagaga aaatttatcg ctagattgga
      121 aaaattttga gcaaagaggt aggagagaac attggaaaat aaaaatgtaa gtatgctgct
      181 ttctttatat gataaagaaa agccagagta tttaaaggaa gcattaacta gtatttttga
      241 gcaaacagta atgccaaaag aaattgtatt agtttatgac ggccctataa atgaaaaact
      301 tcaagtagtt gtcacttatt tccaacaaaa agatcctcac ttgtttacag ttgtaaaatt
      361 agaaaaaaat caaggattgg ggattgcttt agcaattgga ttagaacata cgaaaaatcg
      421 cttagtagcc agaatggata cagatgatat aatggaaccc caacgattag aaaaacaatt
      481 agagatcttc caaaaagatc cagaaatagc gattgttggg agtaatattg aggaatttac
      541 tggcacgctt agcaatgtta tcggaaaaag aattgtacct gaatataaca atgcaattcg
      601 tgtattttct aaaagaagaa atccctttaa tcatatgacc gttatgtttg ataaaaaagc
      661 tattttggaa gtgggaaatt accaaccatt aagtgggttt gaagattatt atctttgggc
      721 aagattatta aaggcaggtt ataaaggata taatattcaa gaaacattag tctatgcgcg
      781 aactggcaaa gatatgtatg caagaagagg cggaatgaaa tatcttggtt ctggtcttat
      841 gggtcgttat cgtatctgga aagacggttt agggtcagta aaagatttta taattgtttc
      901 ttgcggacat atttttatta gcttactacc aaatcaatta agaggaaaat tttatcaaac
      961 gcaattaaga aaataggagg tttttctttg tatagcactg atccaaaaat gaaaaaaata
     1021 caacagatta cgttgaaaat gtctcaagag attgttgatt tttgtctaaa aaatcaactt
     1081 ctttgttatt tctgcggtgg tggtgccatc ggtactgtga gagaacaagg gtttattcca
     1141 tgggatgatg atttagattt ctttatgcct agagaggatt atgaaaaatt ttatcaacta
     1201 tgggttaatt cagaaaaaag taaaaaatat cccatacaga aggcttctaa aaattataat
     1261 gatcataatt cttttacaac tatccgcgat gcagatacta catttattaa aacttatcaa
     1321 agagatttag atatagtcca tggaattact attgatattt tcccgttaga tgttgcccct
     1381 gtttcgaaat ttagccgtaa aattcaaaaa ctatgggctt tagtatatgc tttattttgt
     1441 tctcaagtcg tccctgaaaa acatggtgga ataatggcta caggtagtaa gatactctta
     1501 tctattttcc gctcacctcg tacgagatat aagatatggt cttttgctga aaaacaaatg
     1561 acaaaatata ataatgaacc aacgggctat gtgactgaac tttgtgtcgg acctaaatac
     1621 atgggaaatg tttatcctgc aaaagacttt gaatctgctg tgtgggtgcc attcgaagat
     1681 acagagatgc cagtaccagt tggttatgat aattatttaa gtcaagtttt tggtgactat
     1741 atgcagcttc cacctgaaaa agatcaggtt tctcatcatg aagcagttta tattgatcca
     1801 gaacatccat acacaatgta caaaggaaaa tattatttaa ctaaaggagc agaaaaaaaa
     1861 tgattacagc tattattatt gctggtggtg tgggtaaacg aatgggacaa gatatcccaa
     1921 aacagttcat tacaattgaa ggaaaaccta ttattatcta tactttagaa tcatttcaac
     1981 accatcctca agttgaccgg attttagtcg tttgcaaatc tggttgggaa gaaacgatgt
     2041 gggcgtatat caaagaattc aatattagca aagtcaaatg ggtcattaca ggtggatcaa
     2101 agggacaaga gtcgatcaat aatggtgttc agtttttgaa agactattct gaagatgatg
     2161 atacgatcat catccatgat ggaatccgtc cactagtaga cgaactggta ttgtcagatg
     2221 taatcgttaa atgtaaagaa tttggtaacg gtgtaacctc tctaccttac aacgaacaaa
     2281 tttttatcaa gaaaacagaa gaaacgacgg aacagtatgt cgatcgtaac acattgaggc
     2341 gtgtctcaac tccacaagct tatcaatacg gaaaactacg ggcagcatat gaccgggcag
     2401 tgaaagaaga catcggtatg actgattctt cttatacgaa taccatgatg gtagatttgg
     2461 gagaaacttt atattttgct gctggttctg ataaaaatat caaattgaca acaacagatg
     2521 atctagaatt gttcaaagca tatttaaaaa tgaaagacta ggtgaaagat gatgacgttg
     2581 attaaacaac caatgtacca agaagatttg gcaaaagtaa tcaatcatac accaaaaata
     2641 aaacagctac atggaaaatc cgttctgatg attggtgctt ctggaatgat cggctctttt
     2701 ttgattgata cgttgatggc tgctaatgaa caactaggca tcaaaatcaa agtttatgca
     2761 atgggcagaa accgtcagaa gcttgaaaaa aggtttgcca gttatcttga attagatact
     2821 ttcgaaattg ttgaaggtga cgtcacagaa cccttaccaa aagaaattca agctgactat
     2881 ttgatacacg gtgcaagtaa cacacatcct aaggcttacg caactgatcc aatcggtacg
     2941 atcatgacta atcttgcagg tacagagcaa gtattgaaac atgcagtagc aacccaaccg
     3001 gttagagtat tatttttatc aacagtagaa atctatggcg aaaatcgagg cgatatagaa
     3061 aaattcacag aagattactg tggatacatc gattgtaata cactgagagc aggctaccct
     3121 gaaggaaaaa gagtcagtga atcattatgc caagcctaca tcgcaaaaca cgacctcgac
     3181 atcgtgattc caaggctttg ccgtacgttt ggtccgacga tgcttttatc tgatacgaaa
     3241 gcatcctcac aatttatttt aaatgcagtc gaacaaaaag atattgtttt aaaaagtgaa
     3301 ggaaaccaat atttttcgta tgtatatgtt ggagatgctg tttctgctat tcttcattta
     3361 ctgcttgaag gagaaaaagg agaggcgtac aacgtttctt cagaaaactt tgatttacga
     3421 ctaaaagaat tagcccaaca gctagctgat atcagcggca aacaagtaat ttttgaattg
     3481 ccggatgaga ttgaacaaaa aggtttctca aaagctagca cagcagtact tgaaaataaa
     3541 aaaattaaag agacaggttg gaaaccaatt tttcctttga acgaatcatt ggttcataca
     3601 gtagaattag ttaaaggtga gaaatataat gtgtgagatt agtattattg ttcctgtgta
     3661 taaagttgaa aaatatttaa gaaaatgtgt agattcgatt ttagcccaaa catttactga
     3721 ttttgaagtt atattagtag atgatggatc tcctgacaat agcgggaaaa tctgtgatga
     3781 gtatgctgaa aaagataatc gagtacgtgt gatccataaa gaaaacggcg gattaagcag
     3841 tgctagaaat gcggggattg atgttgcgag aggcaaatac ttaggctttg ttgacagtga
     3901 tgattatatt gatgaagata tgtatgaaat tttgtatgag aatttgaaaa ttcatgatgc
     3961 cgacattagc tctgttgaat tgattccttt ttatggtgat agatataaga aagctaataa
     4021 agaaaagaaa gtaattatat taaataaaaa ggaagcaata aaatctgttt tagaaggaac
     4081 gcaattttat gcatacgcat ggaataaact ttatcgtaag gaacttttta aagataatcg
     4141 ttacttggat ggaaaaacat ttgaggatgc atatataata atagatctat tatttcaaac
     4201 agaaaaaatt gttgtttcca atgaagagaa atatttctat cttcaaagaa atgatagtat
     4261 tatgggaaaa agtttttcta tgaataattt cgatgttata gaagcatggc aatataacaa
     4321 agagaagatt ttagatgctt ttccagattt gcatgattcc tattatcgcc gactatgttg
     4381 ggcatatttt tacgtgttgg ataaaatggt tttatcaagt agttatcaac aaattccacg
     4441 taaaaaaaca gtaattgaat ttttaaagaa gaacagaaat tttatattaa cttataaggg
     4501 attcactaaa tcgcgcaaaa tagctattat tgctctgagc tttagagtag attggtatag
     4561 gaaattggtt gaacaaaaaa ataaaaaaaa ttagaatgtt taaattagta aataaaagaa
     4621 aaggaattga aaactaaaat gtgcagaata agtataatag ttccagttta taatgttgaa
     4681 aaatatttaa aaaagtgtgt cgattcaatt ctaggccaaa catttaccga ttttgaatta
     4741 ttattaattg atgatggttc tacagataat tcaggaagta tatgcgatga acttgcgaaa
     4801 acagacaacc gaataaaagt gatacataag gaaaatgggg gtctaagtga tgccagaaat
     4861 attggtattg aggtagcaaa gggagatttt attgggttta tagatagtga tgattacatt
     4921 gatgaagata tgtatgcatt tttatataac aatatattga aatatgatgc agagttatca
     4981 atgtgtggta tttatgacgt ccataagaat aaagaaatta aaaagttaac tcctttttct
     5041 caattggtta ctaaatctga agcaattgaa ttagtattag atggtaagct agttgttgct
     5101 aatgcagtaa gcaagctata taaaaaagaa ttatttgaga atgtgagata tccaaaagga
     5161 aaaattgctg aagacgcagc agtaatactg aaaattatca atcagtgtaa taaaatccat
     5221 gttgatactt ctcaaaaata ttattattat catcgtggag atagtattac tagtaaaaaa
     5281 tttacaaaaa aagattttga tataattgat gtatggaatg agaatgaaaa atggattatt
     5341 aaaaattatc ctcaaatgta cgataaagta catactagag tttgttgggc ttactttgtt
     5401 gtgttagata aattagtttt aactgaagaa aaaggactgt atcaagaaaa aaaacaagta
     5461 agagagtatt taattgataa tttctttttt attataaaaa ataaacgatt aacttttcaa
     5521 agaaaaatat ctatgttatt gcttactttt ggaattgctg cgtataaaat accggttaaa
     5581 tatcagtata agaaagtaaa ggctgttaat taatgcttta gttaggatga attagatgaa
     5641 aaaaagcagg ttagagtatt ctttaataaa ttcttctata tcaatgttta tatatatttt
     5701 aaggatagta atacaatttg taggtagaag tttttttatt tatttcttag gagcgaaata
     5761 tttaggatta aatggtttat ttacaaatat acttagtttc ttgtcgttgg ctgaactagg
     5821 cataggctct tctattattt attccctata caaaccatta gcccaaaagg atgaaagtaa
     5881 agtaaaggct ttaatgaatt tgtataagaa gacatatgaa tttattggta tttttatcgg
     5941 catagtagga gtattgatta ttccgctgtt acctctattt attaaaaata gcacagacat
     6001 accacatatg tatcgatatt atgtattatt tttattaaat tcagttctta gttatttttt
     6061 cacgtataaa agatcacttg caatagcaga tcaaaaaaat tatctggttg cgattaatga
     6121 ttttgccttt ttattcttta tgaacattgt acaagtaatt gctttgtact tttattctaa
     6181 ttttactcta tttctaatag tgcagatttt gtttactcta ttttctaata taaatatttc
     6241 cagaacagtt gacaagagat attcatattt aaaagagaaa gatgtagttt ctctagataa
     6301 gcaaacaaaa gatgaagtaa agaaaaatgt cataggtaat atgtcctcaa aaataggcgg
     6361 ggttattgta atggggacag ataatatatt aatttctaca tttgttaatt taacagctgt
     6421 aggaatttat tctaactatt cattgattgt cacaagtgtg caaaatttat gtaagcaaat
     6481 tactaattct atcacggcaa gtgtaggaaa ttttgctgta tcaaataaaa aaaaggattc
     6541 atttgagcta tttaaaaaac atttttttat caaccactca ctaatctttt tttcttctat
     6601 attgttattg actttaatga atcccttcat tagcttgtgg gtaggagcca aatacatgct
     6661 acctatgtca acgactattt taattgtttt aaattatagt gtacaggttt atagaaatac
     6721 atccttcgtt tttatagagt catttggttt atattggtct caacggaaaa agcctataat
     6781 tgaagcaggt gtaaacttgt tattatcttt gcttttgtta atagtttttg atatgggaat
     6841 caatggagta cttataggga ctatcggatc gtctctagga tttgtgattt ggtatgaagc
     6901 atttatcata
//
LOCUS       DAZKCW010000098         6885 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000098 DAZKCW010000000
VERSION     DAZKCW010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.101"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..182)
                     /locus_tag="ACG84Z_002563"
     CDS             complement(<1..182)
                     /locus_tag="ACG84Z_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFP9163360.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="ACG84Z_002564"
     CDS             517..951
                     /locus_tag="ACG84Z_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFP9163361.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="ACG84Z_002565"
     CDS             974..1294
                     /locus_tag="ACG84Z_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163362.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="ACG84Z_002566"
     CDS             1435..1626
                     /locus_tag="ACG84Z_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163363.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="ACG84Z_002567"
     CDS             complement(1697..1954)
                     /locus_tag="ACG84Z_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFP9163364.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="ACG84Z_002568"
     CDS             2112..2375
                     /locus_tag="ACG84Z_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163365.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="ACG84Z_002569"
     CDS             2399..2587
                     /locus_tag="ACG84Z_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163366.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="ACG84Z_002570"
     CDS             complement(2670..2855)
                     /locus_tag="ACG84Z_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163367.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="ACG84Z_002571"
     CDS             3070..3441
                     /locus_tag="ACG84Z_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFP9163368.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="ACG84Z_002572"
     tRNA            complement(3591..3663)
                     /locus_tag="ACG84Z_002572"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="ACG84Z_002573"
     CDS             complement(3709..4137)
                     /locus_tag="ACG84Z_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163369.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4955)
                     /locus_tag="ACG84Z_002574"
     CDS             complement(4197..4955)
                     /locus_tag="ACG84Z_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFP9163370.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            5250..5447
                     /locus_tag="ACG84Z_002575"
     CDS             5250..5447
                     /locus_tag="ACG84Z_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163371.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            5553..6035
                     /locus_tag="ACG84Z_002576"
     CDS             5553..6035
                     /locus_tag="ACG84Z_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163372.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(6093..6689)
                     /locus_tag="ACG84Z_002577"
     CDS             complement(6093..6689)
                     /locus_tag="ACG84Z_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFP9163373.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
BASE COUNT         2331 a         1059 c         1353 g         2142 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccct
     4921 agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt tcagctgttt
     4981 atctttccta ttataaatgt atttttattg gaaatggaag tattatattt taatatgtag
     5041 gaaataatta gtttttaagg aatatgtttt aattttttga aaaaaattct tctaaataca
     5101 acagctgttt taattgtgaa aacgaaaaca gtacgctata atgcctgtaa ggttgatttt
     5161 taactgtaaa taaaaatcaa tgagttaaat ctccaaagaa atagcagtgg taatgtggag
     5221 aaaagttcca gcagtttagg aggattttga tgacggaaga aatgattaat ttaggagaac
     5281 aatatgcatg caaaccaatt ggttttacaa aaacggtcat tggtgaagtt gtatcaaaaa
     5341 tgacaaactg cgccgtggtc aaagttgccc aatgtgctgc agaggaccaa gaattattag
     5401 atgaaaaagc aagcatggtt gttgcaaaat atgatacatt tgaataaaga aaacaattgg
     5461 acgtgcggcg tgctgcaagt ccaatttctt tgagaaggta aatcagtatt cttttcctat
     5521 tttctggaga agaaaaagcg aggcgagttg tcatggtaac attctttacg gttctattgt
     5581 ttttattcgt tgttgtgatg tttttatttc tttggctggt tcgaaaagaa attatttatc
     5641 ggactgtgcg aaatcgatgg gtctacttgg tgataccctt cttagtgtca ctagtcattt
     5701 ggtatacact catcagtcat cctacagcag atgaattggc aaaagggatc ttgtcagcaa
     5761 tgatttttat tagttttttg ttggacagta gaggaatcac agaagaagga cttgttttga
     5821 atagctttga caaaaaaggt gttccttttt ctgagatcaa taaaattgta ttatatcagc
     5881 caaaaggttc taaaatcgta aaaatgaatt ttttccgaaa cggatggcga ggaccgatgc
     5941 tgaaattttc tgcatcatta gaagaattag ttccattttt gtcccaacgc ttaaacgatg
     6001 aggcagagat tgatattatg attgatccag aataaaaaca gaggttgcga caagatgttt
     6061 gtcacaacct ctgtttttta tttcaaataa aattatccaa atacgcggaa gcgatcggca
     6121 tcgttcatgt attctttttc cccagccggt gtttctggtg aaccgaatac taattgcgaa
     6181 cgtagtttcc agtttgaagg gatattccat tcttttgcaa ctgcttcgtc aataactggg
     6241 ttgtaatgtt gcaagtttgc gcccaatcct ttatcaacta atgctaccca agtattagct
     6301 gttgcgattc cgtttgattg ttctgaccaa tctgggaagt tgtctgcata taattcaaat
     6361 tgttcttgta gaccttttac cacgtcagta tctttgaaga ataatactgt accataacca
     6421 tttttgaaac cagctaattt gttttgtgta tttgggaaag cttctgctgg agtcaatggg
     6481 cgaagtgctt cttcagtgat ttcccaaagt ttttcatgtg catctccgaa aaggataact
     6541 gcgcgtgttg attgagcatt gaaagcagtt gggctttctt taattgcttc tttgatcaaa
     6601 gttgttaatt cttcattaga aagtgaaaca ttacgtccta gatgatagat tgaacggcgg
     6661 tttttcaaag tgtcagtaaa agttgtcata ataaaatttc tcctttgatt tgcgttttgc
     6721 atttttttaa ttgattacga aatgaagtat agcaccttac aaaaagtaag taaacagata
     6781 tgctcacaaa aaataagcga agttcaaaaa acaattttaa taagaaaaat cgttatgtaa
     6841 ggattttctt agttatcgct ttcattgttg tgttttagga atttt
//
LOCUS       DAZKCW010000099         6614 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000099 DAZKCW010000000
VERSION     DAZKCW010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.103"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            164..313
                     /locus_tag="ACG84Z_002578"
     CDS             164..313
                     /locus_tag="ACG84Z_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163374.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            394..990
                     /locus_tag="ACG84Z_002579"
     CDS             394..990
                     /locus_tag="ACG84Z_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFP9163375.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            1003..1902
                     /locus_tag="ACG84Z_002580"
     CDS             1003..1902
                     /locus_tag="ACG84Z_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFP9163376.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKEQKLAYQRHQQMNREMER"
     gene            1905..2389
                     /gene="ssb"
                     /locus_tag="ACG84Z_002581"
                     /pseudo
     CDS             1905..2389
                     /gene="ssb"
                     /locus_tag="ACG84Z_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2411..2668
                     /locus_tag="ACG84Z_002582"
     CDS             2411..2668
                     /locus_tag="ACG84Z_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163377.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(2827..2961)
                     /locus_tag="ACG84Z_002583"
     CDS             complement(2827..2961)
                     /locus_tag="ACG84Z_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFP9163378.1"
                     /translation="MLKSIKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK
                     "
     gene            3104..3364
                     /locus_tag="ACG84Z_002584"
     CDS             3104..3364
                     /locus_tag="ACG84Z_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163379.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            3813..4019
                     /locus_tag="ACG84Z_002585"
     CDS             3813..4019
                     /locus_tag="ACG84Z_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFP9163380.1"
                     /translation="MRKKFDYLGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIEEKGKKR"
     gene            4019..4270
                     /locus_tag="ACG84Z_002586"
     CDS             4019..4270
                     /locus_tag="ACG84Z_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163381.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGCELHYQENLETYENEYWLTKLEN"
     gene            4286..4723
                     /locus_tag="ACG84Z_002587"
     CDS             4286..4723
                     /locus_tag="ACG84Z_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163382.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCFEIGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            complement(4834..5061)
                     /locus_tag="ACG84Z_002588"
     CDS             complement(4834..5061)
                     /locus_tag="ACG84Z_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163383.1"
                     /translation="MKQNTSITKNTARFNCTAALSRISISPTNSTNNKGIIFFKWITF
                     FLLSYRALPVYFAPPKRRGRLVRNKNHSLSY"
     gene            5159..5347
                     /locus_tag="ACG84Z_002589"
     CDS             5159..5347
                     /locus_tag="ACG84Z_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163384.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IACIGQYLYCIRGRKLYA"
     gene            5465..5671
                     /locus_tag="ACG84Z_002590"
     CDS             5465..5671
                     /locus_tag="ACG84Z_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163385.1"
                     /translation="MKYNLLDHKRMWVEKLEEDLEQLELLGHNKTSTVYKEGLKRTKK
                     AQKELATLESRVQKKEVDLTHTYL"
     gene            5681..5914
                     /locus_tag="ACG84Z_002591"
     CDS             5681..5914
                     /locus_tag="ACG84Z_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HFP9163386.1"
                     /translation="MADKRKEKIQKLLALAADVNDEESVSALAKAQQLMMDYDLTEDE
                     IFNYHEQQRIEAVETHVIYRGRPQKWLYRLFRN"
     gene            6257..6439
                     /locus_tag="ACG84Z_002592"
     CDS             6257..6439
                     /locus_tag="ACG84Z_002592"
                     /inference="COORDINATES: protein motif:HMM:NF013850.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HFP9163387.1"
                     /translation="MSVSTLGITVDAATYYGNGVYCNTQKCWVDWSRARSEIVDRGVK
                     AYVNGFTKVLGGVGGR"
     gene            6429..>6614
                     /locus_tag="ACG84Z_002593"
     CDS             6429..>6614
                     /locus_tag="ACG84Z_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163388.1"
                     /translation="MEDKKEKLFDLIANAYNSKSYNNVEVKEGFLQDAKKIREDKPYP
                     EIIISVYKHLSKLKAEER"
BASE COUNT         2396 a         1044 c         1345 g         1829 t
ORIGIN      
        1 tgtacgtctg aagcctgtga ttttaaaagg tcagaagggt tcatttgaag caacgattgt
       61 tttaaaagaa gacttcacta caggctttga attttctgaa aagaaaaaaa cgaacttcaa
      121 gaaaagaaca cgccgcactg caaaataatg gagggttaat cttatgcgta ataccacaca
      181 caaacaacaa gaaatcgaaa atcaaaaagc caaaattcgt tcagaacagg aaaaaatgcg
      241 tgccagcaaa cgaagactgc agcaattgaa gaaccagcag aggattcaaa aagaaatcga
      301 attagatcga taaaatcttc ctaactattg tatacgtata aacttatgtt atactgtttt
      361 tataagttta tacgtataca aaggagggag aaaatgacaa aagcaatggt atacaagctg
      421 ctagaagaat ttaatggaac tttggctttg aaggatgcca aaaaagcggg catttctcct
      481 gtaacgatca aacgtatggt agatcgaggg gagctggatc gagagtatcc aggttttttc
      541 accttacctg gtcaatttcc tgatgaattg tttatggcgc aaaaaaaata tgaacgcggc
      601 attatttcac atattaccgc gttagatttg tatgatttaa cagatatgat ccctagacag
      661 atcgatctga ctgtacctta cggttatcac gtttctgaaa aaggattgaa ggaattcgca
      721 gttgagctac actatacaaa agcggaatgg tatgaattag gtaagattga aataaaaagt
      781 cgctatggga atcctattat agcttatgat ccagaaagaa ctttatgtga catttggaat
      841 ccctggtata ccgttgagga tgaaatcaaa gtaaaagcaa tcaaaaacta tatggagtcg
      901 gacagaaaaa atcttagaaa attgaatgag tatcgacgaa ttttaccaac agacaaaacg
      961 atgcgttctt atattatggc tttaaattaa aggagaagat acatgacacc tacgcagtta
     1021 aaagcaaaag tgaagaatat ttctagagaa aaagaagttg atccgcagct tgttttaaga
     1081 cattttatga tggaaaaatt cttggaaaaa atctcagagt ctccttatcg tgaaaatttt
     1141 gtgttaaaag gcggcttctt gattggctca aagtatggca ttgaaaatcg cacaaccaaa
     1201 gatattgata cgactttacg ggaaatgaaa gtaaccaaag aaacattaac aacggttcta
     1261 aacgaaattt tttcaacgcc gacgaaagaa ggcattcaat ttgagattca aggaatgaaa
     1321 gaaacgagag aagccgatta ctatccagga tttagcttac gtgtgctggc acatttggaa
     1381 aacatgcggc cagattttaa ggtagatgtg actacaggtg actcgatcta tcctgcaacg
     1441 atcactcaca gtcataaatt gatgtttgag gatcgaacga ttcctttgga atcctatcct
     1501 acagaacaaa ttattgctga aaaattaagt gcaacctttg attttttaac agataattcg
     1561 agaggaaaag atttttatga tctctatact attcctaaaa tggagaagat cgatgagaag
     1621 accttgaaag atagtgtgag aaatacattt acacgtcgag gaaaaactga tccgttaaag
     1681 atatactatg aaaaggatat ggatgtactg aaaaatagtc acgagctaaa agatacctgg
     1741 aagaaatatc aaaaaagcaa tccttatgct gcatcgatca cgtacgatga gacaatggat
     1801 tcgattagta atttgatgga aaaagtgatt cacgtcgaag aaaaagagca aaaactagct
     1861 tatcaaagac accaacagat gaatagagaa atggagagat aaagatgatt aataatgtga
     1921 cattagtagg acgcttaacc aaagatcctg atttacgtta taccgcaagt ggtactgcag
     1981 tagcgacttt taccctagcc gtcaaccgaa atttcacgaa tcaaaacggc aatcgagaag
     2041 ccgattttat taactgcgtg atttggcgca aaccagcaga aacaatggcg acattagcta
     2101 aaaaaggtag cttgattggt gtagttgggc ggattcaaac gcggacttac gacaaccagc
     2161 aaggacaacg tgtatatgtg actgaagttg tagcagataa ctttcaacta ttagaaaata
     2221 aagcagcgac agagagccgt gcgcacgctg atcaatcgtc caccagtcca agcaccgcca
     2281 cctttgaaca acggatacag cgacgcctaa caacaatgga ttgaacgctt cacagaatcc
     2341 atttggtgga caatcaatcg atattagcga tgatgatcta ccgttttagt ttgagaaaga
     2401 aggagtaagc atggcaaaaa aaattagtct gacgatggat ctattgatac ccgtaattgc
     2461 atttatagac gggatttctt tgggcgtcac tgaaaatcct ttggtaaata gaattgcgaa
     2521 aggatcacta tttcttgtat tcgtgtatct tgtctgttct tatcttttaa aaagagcagg
     2581 aaaggataat tccttttggc gattgactaa agtcacagta gcagcgacag ctgttatact
     2641 tacggctatt ctaccgcttt atatgtagag ttaacgggaa atcgttgaac ttcttgcgaa
     2701 atattgctat aatgaacatg aaaaagagga gttgcgctaa caacccctca ttaacagcac
     2761 cgattaaaga acggtggcag aatattagtt atttggaaat aaccgctgac ctgctaaagt
     2821 agacggttat ttctttttgt catttttaag catatttaca atcaaactaa tcaaagcaat
     2881 ggtaaacata ccaaaaccaa gaatggtttg aattgtctca tatgcggaca aaaggcttac
     2941 tccttttata gattttagca cttacattca taagcaccac cacctttcca gaagtcgcca
     3001 ccgtcttcaa actttactgt cttgactatt atagcatatc taaaatcgaa taaaaattct
     3061 caattttaac tgtttttgct ataattttag cgaggtgatc gtgatgaaca aatatgttgg
     3121 tttgcttgat aaaatccgag taataaaaac acaaccatta ttggttcgct ttactttaca
     3181 aacaattcat gaatcgatta attgtgtagt tgcagatatt gaaattatcg ataaattgtt
     3241 aattatggat gatggaaaat acaatattgc cgtcacaggt catttcaata aacggaatca
     3301 attagtcatt gaatcgatgc aaattagaaa ccctgatcat tttacgcgat caatgggcat
     3361 ataaataaaa gaagagctgc aatcctaatg taggactgca gctctttttg ttttacatag
     3421 aaacaggaag aaagggaaag gcctgtttag gaaggcacaa gtgccttctc aattgaaaaa
     3481 cctttctctc actccaaccg ccaccgccgt tcgagaagaa aggaagtgaa cgttgcacgt
     3541 tcactaagat aaggggtctt gctttgtaag acaaaatagg aaaagcttcc tctcaccaaa
     3601 aggttcgttc ctgttcgcta tctctttatt gatttgccag accggcaaca agttgccttt
     3661 tatcaccaaa aagcgacaag gacaagggta aatggcacgc tgcgcgccct tgtccttgtc
     3721 gcttttcgtt gattcattct ggccaacaaa tcaataaaga aagaactaac gaaaggaagt
     3781 aaaacctttc ctaagaggag gcagaatcaa tcatgcgaaa gaaatttgat tatttgggtg
     3841 ttcccttcag cgaattattc ccaaactatc atgcaccaca tactgtcgaa tgcgattgtg
     3901 gagaaagagc gaaatgtatc aaaagctatt gtttgtatca atgtccaaca tgcgggaaaa
     3961 aatatacctt gtcttatggc gattatattt tgattgagga gaaaggaaag aaacgctgat
     4021 gaaaacacaa cacaaattat tgactgtaaa agaagtcgtt caaattttgg tggacaaaga
     4081 agtcatttct gaaaaagtag cagaagcttt acttattccg cggtactgga cgatagaaac
     4141 ccctttagta gaggatgcac cgactatgct atttgaagac ctagtgaaga ttgcaggatg
     4201 tgaactgcat tatcaagaaa acttggaaac ttatgaaaac gaatattggt taaccaaatt
     4261 agagaactaa aaaggagaaa aaaatatggc tcaaaattac tatgacgaat ttgtcaaatt
     4321 acctttggat aaaatggcac aaaaaatgga ggatatgacg ttcctataca acgaaacacg
     4381 tgttccaaaa aaacattata aagaaaaatt gtcggtagct gtggaagaaa tgattgaatc
     4441 aggtgtcgaa atgaatctta ttgcgacgta ctatcgaaca ctggaagaac tgaaaaagca
     4501 aaatgcaaaa tggtttttcc aagccttact atgctttgaa ataggtgtca aaccaagcac
     4561 tattaaacct tctgaatacc aggctttaga actaacgtat gcgaaattta tcgaaacgaa
     4621 aaaagccaag actgtttcaa gtgaatggtt agattatttt gaaaatatca ataagtatgg
     4681 cgcatattac accatgaaaa aggaagacaa cgaaaatgaa taaggtgatt tatcaactaa
     4741 caacggattc catatcaacg atttgaaaga aaaaaaggtc aataatcatt tataccgaaa
     4801 agtgagaatg tgtggaataa ggacaaaaaa agcctagtaa ctaagggaat ggttcttatt
     4861 tcgcaccaac cgcccccgcc gcttaggtgg tgcgaaataa acgggcaaag cccgataact
     4921 taagagaaag aaggtgatcc atttgaaaaa gattattccc ttattgttag tactgtttgt
     4981 tggcgaaata cttatgcgag atagtgcagc tgtacagtta aacctcgctg tatttttggt
     5041 aatactggtg ttttgtttga tcttttggcg gtttgtatta gtcctcgtga gtctactatt
     5101 caagatgatt gcagccatat ttttcatggg gttatttcga tgaaaggaga gagtaccaat
     5161 gccaattgca ataggaaata aacggttacc cgtgacatta gatgaaaaga gacaaaaaga
     5221 attgcagcaa ctaaagcaga agtacggcaa aagtgaatcc aggattatgt gtattgcgtt
     5281 agatttattg attgcctgta ttggacaata tctctattgt attcgaggaa gaaagcttta
     5341 cgcttgaatg cgataagtta acccgatata tcgatccaaa attctatgag gataaaaacc
     5401 tggcatggga actggcttta tagacagagt gctagtgcaa gtaaaggaag aaaggaagat
     5461 caccatgaaa tacaatttat tagaccataa gcgaatgtgg gtagagaaat tagaggaaga
     5521 cttagaacag ttggaattgt taggtcataa taagacttca acggtgtata aagaaggact
     5581 aaaacgaacg aaaaaagcac aaaaagaact agcaacactg gaaagtaggg ttcagaaaaa
     5641 agaagtagac ttaacacaca cttaccttta ggagtagaaa atggcagaca agagaaaaga
     5701 aaagattcaa aaattactgg cgcttgcggc ggatgtaaat gatgaggaat cagtgagcgc
     5761 attagccaaa gcccagcaat tgatgatgga ctatgatctt actgaagatg agattttcaa
     5821 ttatcatgag cagcaacgga tagaagcagt agaaacgcac gtgatctatc gtggacgtcc
     5881 gcaaaaatgg ctgtatcgtt tatttagaaa ttaagataaa aaaggctagt taacaggttt
     5941 gttgactggc cttttttgat atgtttgtac atgttttatt gtgttttaat ttttctcttt
     6001 tttatagcaa gctcctttta taataaatat tccgaaaagt gaagaccatt ttttatttat
     6061 taagactatt attattagtg agataaaatt tgattgatct tacagaatat tggtgacgat
     6121 tatgacacta aagatactat ttatgaaaat tttgcaaaaa tgttctgaaa attacatata
     6181 attgttttat aaaaaaggga ggcaattata tgaagaaaaa atttgttagt attttttgat
     6241 tttaggaatt gttttattga gtgtatctac tttaggaatt acagtagatg ctgcaactta
     6301 ttatggaaat ggtgtttatt gtaatactca aaaatgttgg gtagattgga gtagagctcg
     6361 ctctgagatt gttgatagag gagtaaaagc ttacgttaat ggttttacaa aagtgctagg
     6421 tggagtcggt ggaagataaa aaagaaaaac tttttgactt aattgcgaat gcatataatt
     6481 caaagtcata taataatgta gaagtaaaag aaggatttct tcaagatgct aagaaaatac
     6541 gagaggataa accatatcct gaaattatta tatcagtgta caaacattta tctaaattaa
     6601 aagctgagga acgc
//
LOCUS       DAZKCW010000100         6538 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000100 DAZKCW010000000
VERSION     DAZKCW010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.104"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            89..943
                     /locus_tag="ACG84Z_002594"
     CDS             89..943
                     /locus_tag="ACG84Z_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFP9163389.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            944..2281
                     /gene="xseA"
                     /locus_tag="ACG84Z_002595"
     CDS             944..2281
                     /gene="xseA"
                     /locus_tag="ACG84Z_002595"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFP9163390.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            2286..2510
                     /locus_tag="ACG84Z_002596"
     CDS             2286..2510
                     /locus_tag="ACG84Z_002596"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFP9163391.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            2512..3402
                     /locus_tag="ACG84Z_002597"
     CDS             2512..3402
                     /locus_tag="ACG84Z_002597"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFP9163392.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            3411..4229
                     /locus_tag="ACG84Z_002598"
     CDS             3411..4229
                     /locus_tag="ACG84Z_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFP9163393.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            4336..4785
                     /locus_tag="ACG84Z_002599"
     CDS             4336..4785
                     /locus_tag="ACG84Z_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFP9163394.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            4803..6485
                     /gene="recN"
                     /locus_tag="ACG84Z_002600"
     CDS             4803..6485
                     /gene="recN"
                     /locus_tag="ACG84Z_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFP9163395.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
BASE COUNT         2209 a         1102 c         1506 g         1721 t
ORIGIN      
        1 ttttttctat gaatcatcat aaacctgtta taaatcggga aaattctatg gtagaatgaa
       61 aacacaaaaa atatctggga gtggttagat ggcagaattg attaacggaa aagaattagc
      121 tgaaaaaatg caggcagaga ttgctgaaaa aatccaaaaa ttgaaagata atggtatcca
      181 tcccggatta gtcgttttat tggtagggga aaatccagcc agccaaatct atgtaagaaa
      241 taaagaacgt gtagcaaaag aaatcggaat ccattcattg gtagagcgtt atcctgagac
      301 gatttctgaa gacgaactac ttgcagaaat tgaaaaatac aatcaagatc ctagttttca
      361 tggtatattg gtccaattac cattgccaaa gcatatagat gaagaaaaga tcctgttagc
      421 tatccgccct gaaaaagacg tagacggttt tcatccgatg aatttaggca gactccttgc
      481 gggtaaaccg gacaagattc cttgtactcc atacggcatc atgaaaatgt ttgaagctta
      541 ttctatcgat ccggcgggta aacgagcagt agttatcgga cgaagcaata tcgtcggtaa
      601 accgatggct cagctactct tgatggcaga tgcaactgtt actgttgctc attctaaaac
      661 cgaaaatctg gctgaactgg cacaagaagc agatatttta gtcgtagcaa taggacgtgg
      721 acattttgtc acaaaagaat tcgtaaaacc aggtgctgta gtgatagatg tagggatgaa
      781 tcgtgatgct aacggtaagc tgatcggtga tgtgaaattt gatgaagtgg agcctattgc
      841 aggctggatc actcctgtgc caaagggtgt agggccaatg actatcacga tgctgatgta
      901 tcaaaccgta aaatctgccg aagcttttgg agcaggtgaa tagatggcac aagaatattt
      961 aactgtcact acattaacga agtatttgaa aagaaaattt gatgccgatc cttatttaga
     1021 acgcgtatat ttaacaggcg aaatatcgaa tttccgttta cgtgccaatg cccatcaata
     1081 tttcagctta aaagatgacc atgcaaaaat atctgctatt atgttcaaag gagcattcca
     1141 aaaattacga ttccagccaa aagaaggaat gaaagtcctt gtcgttgggc gtatttcatt
     1201 atatgaagcg ggaggttctt atcaaatcta tgtagagcac atggagcctg atggaatagg
     1261 tgctttatat caagaattgg aagaacgaaa agaaaagctg atgaaggaag gcctttttca
     1321 agggcctaaa aaaatgctgc cacgtttccc aaagcgaatc gcggtcctta ccagtccaag
     1381 cggagcggtt atccgcgata tcatcacgac ggtgaaaaga agatatccaa ttgtccaatt
     1441 ggttttgttc ccaacagttg tacaaggaaa ccaagcagcg gacaatgttg tcaggaatat
     1501 ccagagagta gaagagatgg gcaatttcga tacaatgatc atcggtcgtg ggggtggttc
     1561 gattgaggat ttatggccgt ttaatgaaga gcgggttgct cgggcgattt atcaagctaa
     1621 tacgccggtg atttcatctg taggacatga aacagatacc acgatcgctg atttagtagc
     1681 agatgttcgg gctgccactc caacagcagc tgcagaatta gctgttcctg ttttgtcaga
     1741 agagttgatg cgcattcaag aacggcaagc tagattgcag caggcgtttg tacgccagat
     1801 ccagcgcaaa caagaacggt tcgagcgtgc tcgacgttcc tatgtatttc ggcagcctga
     1861 aagattgtat gaaggtcaga ccatcaaatt agaccagttg aaacagcgat tatatcaagc
     1921 tacacagcaa atttatcatg cgaaagaaaa acaaacgatc gcattaagcc accaattgga
     1981 acaagtggct ccgctttatc gagttaaagc agctcgccaa gaaactgctt atctagaaaa
     2041 acgcttagaa gagaaaatcc aacaatatat gaaacaacag cagcagcgtt ttgctcaagc
     2101 tgttcaatct cttgatttgt tgagtccatt gaaaatcatg ggaagaggct acagctatac
     2161 gacgttaaat gatcaagtag taaaaagtgt caccgagatt catcaagggg atttgctgac
     2221 gatccattat caagatggaa tcgttaaagg acaagtacaa gagatagaca aaggagaata
     2281 aaaatatgga aaatccaact tttgaagagt cactgcaaga attagaaaaa attgtcatgc
     2341 agttagaaca aggagacgtt ccattagaat cagctctaga ttcgtttaaa cgaggaatgg
     2401 aattaagcaa acattgccaa gatacattag ctaaagcaga agagaccttg acgaaaatga
     2461 tgacagaatc aaatgaagaa gttgattttg acggaaacga ggaaagctga gatgagatta
     2521 actgactttt cagctattca tctacctgct gtagaaaaag aaatcttgtc ttttttagat
     2581 gagcatacaa cggatagagg actctatgat gcgatgagtt attcagtgaa agcaggcggg
     2641 aaaagaatac gtcccttatt acttttaacg gccgttgctt cctttgatga gcctattgat
     2701 gttcccgtct atcaagtagc agctgcttta gaaatggtgc atacgtattc cttgatccac
     2761 gatgatttgc ctgcgatgga caatgatgat cttcgtagag gaaaacctac caatcataaa
     2821 gtattcggcg aagcattagc tatattggcc ggagatggtt tgcttacagg agcattccag
     2881 ctaatcagta tggcacactt aggtaattct cctaagcttc tgctgcttca gcaattagct
     2941 gtttgtgcgg gatcacaagg tatggttgct gggcaagctg cagatatcga gggcgaatcg
     3001 aaaaagcttt ctttagaaga attagcattt attcatgaaa gaaagacagg gcatttgatt
     3061 cgttatgcct tgctggctgg tggcatatta gcgaagcaac ctgaagaaat cttattgcta
     3121 cttcaacgat tagccgaaca tttaggttta gcttttcaga taagagatga tctactcgat
     3181 gtgattggta caacgaaaac attagggaaa acagctggta aagatgaacg tatggaaaaa
     3241 aatacttacc cgcgtttatt aggcctagaa aagacacgtg aggcgttgga gattgagctg
     3301 ttatccgcca acaagatcat agacaaatta gaagaggacg ttttttcttt tgatggcggg
     3361 ctgatgcgcc agatgatcaa gcaatttgat gtggagaaat gagggaaaga atggaaaaag
     3421 aacgcgtaga tgtattagcg gtcaaacaag gattatttga aacaagagaa caagccaaac
     3481 gttcagtgat ggctggtttg atttacaacg aaaaaaacga gcggtttgat aaaccgggag
     3541 aaaaaattcc agtgagtagt gaattaagag tcaaaggtaa aaaacttcct tatgtttctc
     3601 gagggggatt aaaattagaa aaagcactca aagcatttga tctatctgtt gaaggaaaaa
     3661 cattgttaga tattggtgca tccactggcg gatttactga tgcagctttg caaaatggcg
     3721 caaaaatgag ttatgcttta gacgttggct acaatcagct agcttggaaa ataagacaag
     3781 atcctagagt cgtcgtaatg gaaagagtga attttcgtta tgcaaaaccc gaagacttta
     3841 ccttaggaat tccagaagtt gctgttatcg atgtttcttt tatttcacta aaactgatgc
     3901 tgcctccatt acatgctatt ttaaaagaag agggagaagt gattgcttta atcaaacccc
     3961 aattcgaagc aggcagagaa gctgtaggga aaaacggaat tgttcgtgac cctcagaccc
     4021 atcaaaaagt tttagaagac attttgtcat ttgcggcaca aggtggatat gatgtgctgg
     4081 aattaagtta ttctccgatc acggggggag aaggaaatat cgagttcttg gctcacttga
     4141 ggaaagtacc cgaaagcgga acaatcaatt cagctattaa tatggcagaa gtggtttcaa
     4201 atgcacacga acagtttgac cataaataaa ttgtaactgt gaaaatcaag tgagaagtat
     4261 gcggattctt ctttattata ccaaggaaat aagctatcat tgattaagaa gaatatgcta
     4321 aggagcgaag acgtaatgag aaaaaaagat cggcatcgtt tgattactcg attgttgagt
     4381 gagcaagata tccgaaagca ggaagaattt gttgaaatcc tgaaaagcaa aggaatatct
     4441 gttactcaag ctacgatttc cagagatata aaggaactga aactgatcaa ggtaccggct
     4501 tcagatggcg gctaccgtta tagcatacca gctgaaacaa acgaagatgt aaatactaaa
     4561 ttggaaaaac tattaaaaga cgctttcgtg gcagttgacc aaatggaaaa atttgttatt
     4621 ttgaaaacat tgccgggaaa tgcttcggca gcagcaaatt tgattgataa acgttacaag
     4681 aaagaattat tttcgattat caatgatgac gataatgttt tgatgattac acgaactgaa
     4741 gaccaggcag ttttattgaa gaaagacttc ctgcattacc tttaagttga ggagcgaatg
     4801 tgatgctaca agaaatcagt attactaact ttgcgattat tccggaattg cggctttctt
     4861 ttcacgaagg aatgaccgcg ctgaccggag agactggtgc gggtaaatcc attattatcg
     4921 atgctttagg tctgttagca ggaggaagag gttcaagcga ttatatacgt caaggagcag
     4981 aaaaatgtgt gcttgaaggg ttgtttgaac taccaaaaca agaaggattc tctgaactga
     5041 tggttgaatt agggatcgaa acagatgagg acaatctgat tgttcgacgg gatatgtcct
     5101 taactggaaa aaatgtttgt cgagtgaatg gtcatattat cacattagct aatctgagaa
     5161 gaatcggcag ttatttagta gatatccaag gacaaaacga acatcaggaa ctgctccagc
     5221 ctgaatcaca tcttgcttta ttggatcgtt ttggagatgt agctttccaa cagaagaaaa
     5281 agagttatca gcaagaatat atctcttatc gtgagctgga aaaaagggta cgaaaagtgc
     5341 agcaaaatga aaaatcctat gttcagagaa tagatatgct ccatttccag caagaagaaa
     5401 tagctgctgc tgatttgcaa gtcggagaag aagagaaatt aaaagaagaa agagaaaaac
     5461 ttagcaatta tcaaaaaatt gctgatggat tagctgcagg ttacggagca ctgacgaata
     5521 atgaacaaaa cagtgtagat ggtgttggct tggccgtttc agaactgcaa gggatcgccc
     5581 atctagatgt ggagtatgaa gcaatttatg aaaatatcca aagtgcttac tatttgctgc
     5641 aagatgcaat cggcgatatg agtcgtcaga ttgatttatt ggagttagat gagagtcgtt
     5701 tagaagaagt tacgcaacgt ttagaattaa tccgacagtt gaaacgtaaa tacggcgaat
     5761 ccattgagtc aatattggct tactatgacg aaatcaccga agagctagct tcttctgatt
     5821 tttcagaagg tcaattggac aaaatgaaag aggaactaga gcaaaaagag cttctacttc
     5881 agcaacaagc cgcagatctt catgaagcgc gtaaaaaaat cgcaaaagaa ttggaaaaat
     5941 ccattctgca tgaattgaaa agtctgtata tggaaaacac tgagtttgag gtacgtttct
     6001 taaaagaaga aaatagacaa ttgaatcatg atggatttga ccaaatcgaa ttttacatta
     6061 cgaccaatcc aggagagcca ctgaagcctt tggtgaaagt cgcttctggt ggcgaactgt
     6121 ctcggatgtt gcttgctttg aaaactattt tttcttctga gcaaggtgtg acaagtatta
     6181 tttttgatga agtggataca ggtgtgagcg gaagagttgc acaggccatc gcagataaaa
     6241 tttctcaaat atcgaaatac tctcaagttt tgtgcatcac tcatctgcct caagttgctg
     6301 cagtcgccga ctatcaatat tatattgtga aagcagtgat tgatggacgt acgcaaactt
     6361 ctgtttcaga gttgaaaaca aaagaaagag aagaagaaat tgcacgtatg ctggctggaa
     6421 gtgagattac aaaactcaca ctcgaacatg caaaagaact attgaaactc gcaaaaagga
     6481 cctgagccac ctcgcagtgg ttcaggtcct tttcagcagc tgatagctat attttatt
//
LOCUS       DAZKCW010000101         6474 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000101 DAZKCW010000000
VERSION     DAZKCW010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6474
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.105"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(99..1229)
                     /locus_tag="ACG84Z_002601"
     CDS             complement(99..1229)
                     /locus_tag="ACG84Z_002601"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFP9163396.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACG84Z_002602"
     CDS             complement(1878..3080)
                     /locus_tag="ACG84Z_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9163397.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACG84Z_002603"
     CDS             complement(3140..3343)
                     /locus_tag="ACG84Z_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFP9163398.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACG84Z_002604"
     CDS             complement(3485..4552)
                     /locus_tag="ACG84Z_002604"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFP9163399.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACG84Z_002605"
     CDS             complement(4610..4717)
                     /locus_tag="ACG84Z_002605"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163400.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACG84Z_002606"
     CDS             4880..5692
                     /locus_tag="ACG84Z_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163401.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACG84Z_002607"
     CDS             complement(6066..6257)
                     /locus_tag="ACG84Z_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163402.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
BASE COUNT         1954 a         1317 c         1013 g         2190 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaa
//
LOCUS       DAZKCW010000102         6447 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000102 DAZKCW010000000
VERSION     DAZKCW010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.106"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            40..897
                     /locus_tag="ACG84Z_002608"
     CDS             40..897
                     /locus_tag="ACG84Z_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFP9163403.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAKRYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            917..1477
                     /locus_tag="ACG84Z_002609"
     CDS             917..1477
                     /locus_tag="ACG84Z_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HFP9163404.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            2532..3299
                     /locus_tag="ACG84Z_002610"
     CDS             2532..3299
                     /locus_tag="ACG84Z_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HFP9163405.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            3325..3870
                     /locus_tag="ACG84Z_002611"
     CDS             3325..3870
                     /locus_tag="ACG84Z_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163406.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            3871..4437
                     /locus_tag="ACG84Z_002612"
     CDS             3871..4437
                     /locus_tag="ACG84Z_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163407.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMEKENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGADDCVAYYTTAE"
     gene            4452..4700
                     /locus_tag="ACG84Z_002613"
     CDS             4452..4700
                     /locus_tag="ACG84Z_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163408.1"
                     /translation="MEGMDFLDHEDLVDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDDTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            4720..4959
                     /locus_tag="ACG84Z_002614"
     CDS             4720..4959
                     /locus_tag="ACG84Z_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163409.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEDLLRKTQRKGYPDKILKQIGYYM
                     PEERIEKEFCEVLFDSEQLLVLLTQNKLICQFENN"
     gene            5330..5611
                     /locus_tag="ACG84Z_002615"
     CDS             5330..5611
                     /locus_tag="ACG84Z_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HFP9163410.1"
                     /translation="MKVKNPTEKSRIQVGIDKNLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTKDMPVDVLDTDEKLEEWFDEA"
     gene            5601..5942
                     /locus_tag="ACG84Z_002616"
     CDS             5601..5942
                     /locus_tag="ACG84Z_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFP9163411.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIAEWEKAGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSASDTKKL
                     NRFIEKLQRKV"
BASE COUNT         2398 a          899 c         1296 g         1854 t
ORIGIN      
        1 ataaattgct tgaagtatta tatttagata tcataattta tggaagaaaa attaattaaa
       61 aaggatgaga ttataatggg gttactggtt ccgagagcta atacttatac tataccttta
      121 acgaaacgcc aattaattgc taaaagatat caaaggatta ctagagccat caatagagag
      181 ttttggaatt ctgaaagtga tactgctcac agtttatacg taggttctta tgggagagga
      241 acggcaatta gtactagtga tatagatata atagttgaat taccgatggc agaatttgac
      301 agattcaaaa attatttatc aaatggcccg tctaagttat tacaagttat aaaaaacgca
      361 tttcaggaaa tactaccaaa tagtgatatt agagctgatg gacaagttgt taaaataaat
      421 ttccatgatg gaatcaaatt tgaaatagtt ccagctttta atgaaaaaga ttattggggt
      481 gagtcaaaag ggtttattta tccagattca aacatgggag ggaactggaa agctacaaat
      541 cccaaaaaag agcaagaagc catgaaatta aagaatacaa aaagtaataa tttattatat
      601 gctacgtgta aacattttcg acatgtacga gatacagaat ttacgagtta tcatctttca
      661 ggaatagtaa ttgacagttt cgtatatgag gctatgggaa attggaaatt cgttgaaaat
      721 aacagtgggg gtcaaaacat tagttctgta tcttatgaga cagctttatt agaatactat
      781 aactcacata aagttatggg cggtttaaat ttatactctc ctggaagcaa tcaatttgtt
      841 aattctgata gtagtatcat atgtttagaa aaagtattaa aaaaaatagc tttataaagt
      901 tttatggagg aacaacatgg gagacgaaaa aaagcgcttg gaagttcaat tacgtgaagc
      961 atatggacga gtaacgtata cttacaccac tcatttaaag caagccgata atattatttc
     1021 tgacaataaa attttaaggt gtcttcaaat tggtttgtca gcccttacta ctggaggggt
     1081 acttagtacc attattactg ataatagtga gttaaccttt gttgctggat tatgttcaac
     1141 aatttctctt ggattaaact tatactttaa gaactttgat cttgctgaag aagctaaaaa
     1201 tcatcaaatt gttgccgata aattatggtt gatcagagaa gaatacgtaa gcttactaac
     1261 agatttaaat cgtttaagtg ttgaagatat tgtgaaaaaa agagatcaat taatgaacga
     1321 aactcatgaa gcatataaaa atgcccctaa aacaaatagt aaaagctatg aatcagctca
     1381 gaaagcatta aaatctgaag aagagcaatt ttttacagaa gaggaattgg ataagatgtt
     1441 accagagcat cttagaaaaa agagttctaa atattgaact ctttttttat gcttaaaatt
     1501 ctcttgtaat ttttctattc aatcaataaa taatctatat ttaagaagaa atatgatgat
     1561 agaaacatct cctgaagcca ccgcaagccg ttctaagcat agcttagccc gacattgcta
     1621 gatatgctca tctcaccatg aacgtttcct aaagccaccg caagccgtcc tagccattgc
     1681 ctagtccgac atcgctagat tagtgcatct cgccataaaa gttttctaaa gccaccgcaa
     1741 gccgttctaa gcatagctta gcccgacatt gctagatatg ctcatctcac catgaacgtt
     1801 tcctaaagcc accgcaagcc gtcctaagca tagcttagcc cgacattgct agatatgctc
     1861 atctcaccat gaacgtttcc taaagccacc gcaagccgtt ctaagcatag cttagcccga
     1921 cattgctaga tatgctcatc tcaccatgaa cgtttcctaa agccaccgca aaccgtccta
     1981 gccatcgcct agtccgattt tgcttgatcg gttccatttc tgtttattta gtgggtcaac
     2041 accgtaatct taaatagcca tcgcctattt aagattacta ggtctgcttt gaaggtaaaa
     2101 agtctttcat tcttcaagac ttttaggctt tcaagctacg cctgaaagca ttgaaattca
     2161 tcgctcttta tttggttttg ccatttataa ttccttacgc ccattatctt tttcgcctgt
     2221 cttgccttgt cagaagtgtt tagagcttat ctcatctttg gattaataca agtggcgtaa
     2281 atttttttct aaacgcaagc gttacgaaaa taatttactt aaacacttgt attaatccgg
     2341 cagataagaa cgcattctaa tcactcccga caaggcaaga caggcgaaaa agataaataa
     2401 atgaacgaaa ggaagaaaca taaaatgcaa aaccaaatag cgatgaagaa aaaaccacct
     2461 ccctctaaaa caatccaaac aaaaaagaat tttgaaaaac caaaaatcaa aaacagaaag
     2521 aagcgttcaa catgagagat agaattttag aagttaatca agaaatggta aacaagttaa
     2581 caaatatcag tgggaactat gaaaagtacg atggtacttt acttgataac tatatttttc
     2641 acgatacaca aaatatcaga attggcagaa gtaaaccgag agcgttcatt ctcatcaaag
     2701 agaaatattt gaatgaatgg aatagcacct atgaaatggt tatgactgat aactttgaaa
     2761 aggtattgga tttcagaaat gctttgttgg gttctgatat gggaaatagc agtcttgaat
     2821 ctattgaagt tgaaaacaag accgagaatg aaggtgaagg attgattaag aatgtcttga
     2881 aaatcgaaca aaaatatatc agtgaagata gaagttttta tagagtcaca agctcggttg
     2941 gtctagcaaa ctttgctact aacttaattg gaaacaatgc tagtgaatct ttgctagtga
     3001 tgtgtctgaa tacaaagaat gaggtcattg cttatagcga agttttcaaa ggtggaatta
     3061 atcaatcagt agcgatacca agagagattt ttcaactagc tttgctaaac aattcagcaa
     3121 aaatcgcagt atcacataat catccgagcg gatatgaatt tccaagtgaa aatgacaaaa
     3181 gttttactac gaatttgaaa aacgcaggaa aaacaattgg tattgaattg ttagaccata
     3241 tcatcgtaac aagtaaaaac acaagctatt actcatttca agaaaatggt tctttataaa
     3301 aattagagaa aagaggaaaa caagatgggc gaaagaacac aagcgttaat tacagtcaaa
     3361 tatggtaaca gcaaaacgaa agcaagcgtg tcgattcatt atcagtgggg gtatggtcga
     3421 tatatgctga tggacgtatt gaatcaagga atttatttaa tcaataaagc atacgactta
     3481 cgagataaat caagagaaga attagcaaaa ggaatctttg atagaagtac aggagttatc
     3541 aattttgtta cctatgaatc tggagtgagt gcttatgatg aaacagggtt tggtgggcgc
     3601 tatgaacctt atcaagaaac gattgaagat gtgatgaagt tttcagataa caatgatggc
     3661 tatgctcatt tagagatggt gttcgatgaa aatggattta gtctagatga taaaaccaga
     3721 ttgcgattgt ttgattttga gggtcaacag ataggactaa acaagttttg tgaaagcgga
     3781 aaagagtttg ctacgaaaga ttttattaag ggatacagat tattgctaga aaattatgga
     3841 ataaacctag aagaagagag cgtgaaataa gtgtttgaaa aaagaaaaga ccagttccct
     3901 aatttagaag cgaaaagtca aaaagtgatt gatggtgaaa tgattgaatt attccaaaaa
     3961 agttatggaa ccatagaaac taccgcaagt tgcaaatact actttcaagg aaagagaaac
     4021 acgtttaaag gctttgccga ttctgatgaa gaattggcaa agaaaatcat tgattggctt
     4081 gtcagcagtg aacacgtagc aagagaagat accgttagaa caacgattaa tggggaagtc
     4141 ctaacaggta ctagatgtgt ttgttgtaat catgaatttg tagaagatga aggttgctac
     4201 cgaatcaatg aatatggtga ttttatttgc cagagttgcc acgagataga atttccaacc
     4261 gaaagaagtt ggtttgaata catgctacaa gattatgaga tggaaaaaga aaatggtgaa
     4321 gtagtttttt gtaccaaaga ggaattgagt aagagaagcg atgatgaaat tgaagattgg
     4381 tgtgtgtggt tagtaggggc agatgattgc gttgcatatt acacaacagc agaataggag
     4441 tgtgaatcag catggaagga atggattttc tagatcatga agatttggtt gattttggtt
     4501 atacatggaa aggaatggta ggtattagca gaagtcttgc taatgccttt tacgaaagaa
     4561 attatgcagt atatgttctt tatgatgacg atacagaaag ccttgttgac gaggaatata
     4621 aattggattt agagaatgtt ttatatggaa tagaaaagga agatttagca aaatatattt
     4681 tttcatggtt gggtcaataa gtgaaaggaa gatagaaaca tgacaaaatt taaaagtaag
     4741 ggtatgcaat ggtgttctta ttattatgtt ggaaatgatg aagatttatt gagaaaaacc
     4801 caacgaaaag gttatccaga taagatattg aaacaaatag gttattacat gccagaagag
     4861 aggatagaaa aagaattttg tgaggttctt tttgatagtg aacagctatt agttttgtta
     4921 acccaaaata aattgatttg ccaatttgaa aataattaag atgaggtggt gaaccatgaa
     4981 tgaagataag atggtattaa gtgaatatgc tagattgaga actattaatt ctttagcatc
     5041 tcatttaagt tgttctttcc taacaaaggt gctaaaatta atttacaaat gtgaagattt
     5101 tgtacaagag aagcacaaag acaagcctac tgcgaatagg cttgtctttt tttcattcat
     5161 tacgattccg tatgtgtggg ttagcgacaa tttgttcaat taccgtatga tatagcatct
     5221 taatttgatt agattacttg caatgtagtt tattaagagt ataatataat cataaatgtg
     5281 gacaatttga gaaataatga gtgttttata ctcaaaagga gtggatgaaa tgaaggtcaa
     5341 aaatccaact gaaaaaagca gaatccaagt cggaatagac aagaatttaa aagagaacgc
     5401 agaaatgata ttggaagagc taggtttaaa tcctacaaca gcaataacaa ttctttacaa
     5461 acaagtagtc gctagaggtg agtttccagt agagataaag ctaagtgaag aggagaagca
     5521 aggaatcaga ttgcaacagc taactaagga catgccagta gatgttctag atacagatga
     5581 aaagttagaa gagtggttcg atgaagccta atgagatagt aacggtctat gttgcattta
     5641 cagataaaaa tggtggtaaa agaagaccta ttttggtggt tagtgataaa gaagatagag
     5701 tagaattctt tggaatcaca agtcaatatg agaaaaaatc agaccaaata aagagggtgt
     5761 attttcctat tgcagaatgg gaaaaagcag gacttaaaaa gcaatcatgg attgacgtag
     5821 ggtctttaaa ggctattccc aaaagccgag agaacatatc attcaaaaag gttggtatgt
     5881 tatcagctag tgatacgaaa aagctaaata ggtttatcga gaaattacaa agaaaagtct
     5941 aacaaggctt ttcttttttg tttatatgta tattaagata tacgtttata taaacgtatt
     6001 tatgtatatg aaaatatacg taaatatata cgtgattata aacattaaga aaacgttaag
     6061 aattgttaaa tagtgatatt tagtaatata cgaattataa gatatatttt atatagaatg
     6121 tatgtaaata aataaaatgt ctgacggata ttgaatagca ataaataaca ataattcaga
     6181 cggatacagt gagtgaagta gcttgctacg aacgaacagg cagaatgaaa cggcagtttc
     6241 attagagcaa gtcgcttgcg acgtagcgtt accgctgatg taactggcaa gttacataga
     6301 gagagtttgc ttgcaaacga acgttaccta cttgaataga aataaaaaat aacagattag
     6361 tgaattttga ataggagcca caactcaacc aaccgcttgc ggtgggtgag tcccacggag
     6421 gaaaagacga acgaacggtc gcgtagc
//
LOCUS       DAZKCW010000103         6359 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000103 DAZKCW010000000
VERSION     DAZKCW010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.107"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..220)
                     /locus_tag="ACG84Z_002617"
     CDS             complement(<1..220)
                     /locus_tag="ACG84Z_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HFP9163412.1"
                     /translation="MNILILSCGRRCELVNAFKTALNNNEMEGKIIGADCSELAPALY
                     MCDEKIVLPKVSESNYIEELIKVIKFFEI"
     gene            complement(232..2049)
                     /locus_tag="ACG84Z_002618"
     CDS             complement(232..2049)
                     /locus_tag="ACG84Z_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFP9163413.1"
                     /translation="MFVLTRRRKIATLVVVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            complement(2062..2826)
                     /locus_tag="ACG84Z_002619"
     CDS             complement(2062..2826)
                     /locus_tag="ACG84Z_002619"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFP9163414.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFRKNPNYLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIGKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(2854..3552)
                     /locus_tag="ACG84Z_002620"
     CDS             complement(2854..3552)
                     /locus_tag="ACG84Z_002620"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFP9163415.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLSNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQIFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLSKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(3564..4343)
                     /locus_tag="ACG84Z_002621"
     CDS             complement(3564..4343)
                     /locus_tag="ACG84Z_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFP9163416.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKEAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNGKTAPSRRSRSRV"
     gene            complement(4359..5303)
                     /locus_tag="ACG84Z_002622"
     CDS             complement(4359..5303)
                     /locus_tag="ACG84Z_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFP9163417.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(5349..6128)
                     /locus_tag="ACG84Z_002623"
     CDS             complement(5349..6128)
                     /locus_tag="ACG84Z_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163418.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTIVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIDQIRNEKIRAAYATKAQTVAQQMGYSNISY"
BASE COUNT         1682 a         1324 c         1134 g         2219 t
ORIGIN      
        1 taatttcaaa aaactttatt acttttatta attcctcaat ataattactt tctgaaactt
       61 taggtaatac tattttttcg tcacacatat atagtgcggg tgctagttca gagcaatctg
      121 ctccaatgat ttttccttcc atttcattat tgtttaatgc tgttttaaat gcattcacta
      181 gttcacaacg acgtccacaa cttaatatta aaatattcaa tttttaatct cctatctatt
      241 cgaagcattt gcaaaagtga caatgtcttt agccagttgt tcatcgtctt gtggcaggct
      301 cttaacaaaa tccatcactt tttgtattga gtaacctttg atgtttccta caaagatttt
      361 ctcataaact gcttcatcat ttctttcctt atccaacaat agttcttcat atagtttttc
      421 ccctggacgg atacctgttt caatgatttc gatttcgtct tcgctatacc cgctcaatcg
      481 gatcatgttt ttggctaggt ctacaatctt cactggttca ctcatatcta gaataaaaat
      541 ttcgccacct tttgctaatg cgccagattg aataactaaa cgactcgctt caggaatcgt
      601 catgaagtat cgggtcatac gaaagtctgt tacagtgatt ggaccacctt gagcaatttg
      661 ttctctgaat actggaatca cactaccgcg agaaccaagg acattcccaa atctgacagc
      721 tgagaatttc gtacagcctt cttcattcaa tccagtcacg atcatttcag cgattcgttt
      781 tgttgaaccc atgacgtttg gaggattgtt agctttatct gtcgatacca tgacgaagtt
      841 tttcactttt gctgctttag ctgcttctgc tacatttttt gtaccgaaaa tattgttttt
      901 gactgcttct tttggattat attccatcag tggtacatgc ttatgagcag ctgcatggta
      961 gacgatatct ggatgatatt gttccatgat ctcattgatt ttctcgcgat cttggatatc
     1021 tgcgatgatc ggtacgattt ctgtaggaca attttgatga tgcgtgcgta actcacggtc
     1081 aatcaagtag atcgagttct ccccatgtcc taaaagcaat agctttgcag gattgaattg
     1141 aatgatttgc cgacagattt ctgaaccgat cgatcctcct gcgccggtga caagaatgac
     1201 tttgtctgtg atctgatctt tgatggattc aatatccagc tttacctcat ctcttcccag
     1261 taaatccact acgtcaattg tttttaattt tgatacgcta atttttcctg aagcaagttc
     1321 ttctatagaa ggcatcgtgt tgactttcac acgagcggat tcgactaact cgaagattct
     1381 tcgtaatttt tttcttgata aggaagggat agcgatcgtt accatttgaa tgtcatattt
     1441 ttcaatcaat tccggaatat cttttaatgc acctaatact ttttttcctg aaagatacgt
     1501 atttctttta tttggatcat catctacgaa cccgacaacg tggatatctt gagccgtttt
     1561 ggatccaaga aagctgttgt ataaaatacg cccgccttcg ccagcaccaa caatcaatgt
     1621 atttttagca gaatctgctg atacatatct catatttttt gtttcgatgt agatacgcca
     1681 gatcaatcgg ctaccgatga tcaataagag cgaaagcaga taagcaaaga taactaaccg
     1741 taaactgtat cgccgattaa tgaacagcag tatgaggata cttgaggcag cacttgcaga
     1801 tagtgaacta aaaattgcaa tgatctctct taaatttgta tagcgattga ttcgagtgaa
     1861 aactttaaat aaactaccat aaaataaata aaaaccaatc gacaaaccaa tagagattaa
     1921 aataaggtcc attggtatag ctacaaacgg cttcatgaat ttagctgctg caatatttgc
     1981 agcgattaat aacaagctgt ccacaacaac caatgtggca atttttcttc ttcttgttaa
     2041 tacaaacacc ctacattccc cctaaaataa accaaatttc ttctttttta cctcttcata
     2101 gactggataa ctgatttcat ccccgttgat cagatccttt gcgacttgtt tcatctgtac
     2161 tactttttcc ttaccaaagt ccttgccaat ctgctcatag cactctttta agtaaaaggt
     2221 gcgcttagag accccatggg catcagaagc agccatctgc acgagattat gtttgaccat
     2281 cgttttagct gttttctgga tgtctttgcc aaacacccca acataacttg gcgcagtaag
     2341 ttgggccaaa caccccatat ctaggaacgg aagcaaataa ttcgggtttt tacgaaaatg
     2401 cgcgttacgt tctggatgga cgatcactgg tgtctttcct agttctaaca actcaaaaaa
     2461 aagccgttct gcatataacg gcacttccag tgtcggaaat tcgatcagaa gatatgtatc
     2521 atctaaatct gtaaataaaa tttcatctcg gtggatgtct tcgatgagcg ttccggtaat
     2581 acgtacttct tgtccttcca ataacgtcaa aggcaattgt cttttctcta attcggcttg
     2641 taacgaagcg actagagaaa tgacttgtga tttttcattg ctgtattttc cattattgtg
     2701 gtgtggtgtg cataaaatat gcgtgatgcc ttgctgaatc gctttttcag ccattgcaat
     2761 acttgcttct aagttttctg ccccgtcatc gattcctggt aggatatggc aatgtagatc
     2821 gatcatttct cttgtctcct ctcttcttat tccttaattt ccgtagtaat aaccagcatc
     2881 tttgctatgt tctgctccgt tgtatacaac acctaagact cgtgcttgta ccatctctag
     2941 cagttctttt gctttagaca aggattcttt acgtgatgta ttttcacgta cgaccaataa
     3001 agtgccatcc gtttttgaag acatgatctg tgcatctgtt acggctacta ctggtggcat
     3061 atcgaatatc accacgtcaa atatctgtct tgcttcggct agaatctgat ccattcttgg
     3121 cgagcttaac aattctgatg ggttgggtgg cttaggccca ctaggcaaaa tcgacaagtt
     3181 ctcgactggc gttcgttgga tcacatctgc tacacttcct gatgaactaa gtgctgtact
     3241 taatccacta gcattgctca actggaatgt tttatagacg acgggtttac gtaaatctgc
     3301 atcgactaat agaacccgtt gaccggattt agcaaaaacg actgcaatgt ttgctgcagt
     3361 ggtggatttt ccttctccag gacctgatga agtcacgaca atcgttttga tttgctgacc
     3421 agctgcggag gcaaactgga tattcgtccg gatcgtacga tattgttcgg cgattggtga
     3481 agatgggttt gttaatgtga tcaaactgac tgcatgagtt tgtgctgctt tttgtttctg
     3541 tgttcgtgcc atttttcttc ctcctagact cttgagcggc ttctgcgtga tggcgctgtt
     3601 ttaccatttg tagcttttgg tcgtgcagga gctgatcctt ttttacggat accagcgttc
     3661 aattctttcg ctgacatttc tggaactgtt cctaagattg ggaatcctaa tgtatccgtc
     3721 acatattttt catctttcac tgtccgatcg agtaattcga ataagaatgc cagacctacg
     3781 cctaccatca ttcctaatac taagccaatc actaaattca atttattatt tggcgaaaca
     3841 ggtgtcgtat tggcaactgc acctgaaata atcgagattt tatcgacatt catcacgtct
     3901 tttgcgttct cttggaaaac ttgtgaagtt gtgttagcga tctgttgagc agtcactgca
     3961 ttcgtgctta ttgcctggat cgagaacatt tgtgaatttt gtgactgatt gactgagatg
     4021 gcctctttga tttgttcagc agtcattttc acattgtctt ctgtttctaa acgatctttg
     4081 acttcattta gcactaaatc actgacgatc atatctttat acgtattgat catttgcagg
     4141 ttcgtattga catcattgac atttgctgtg tctgattgtg gcagtgtcac gatcaattgt
     4201 gcttgtgaac tgtattttgg tgtcaagatg aaaaatgtta cgattcctga gatggccaag
     4261 ccagcaaaca ttgagatgat gattgttacc aagtgtttgc gtaatgtttc aaaaatttct
     4321 ttcaagctga ttgtctcttc cattttttct ccactttcct atttattctc tagattcatt
     4381 tgatctttta attctttttt cacacgatca agttcttgat cgctgacttt ttgataggag
     4441 atattatctt gcatgaagcc ttctccttgc agctgatctt gcttgatcgt accaaatgcc
     4501 tcccgataat ctaaagcaat ttttttcatt tcatcaaagc tcatgtctgt tttcatattc
     4561 gactctagag cattcaaaac ggattgatag ttgctgacac cgtttagact caatactttt
     4621 ttcgctacac cttctacgat ctttctttga cgctcttgtc taccatagtc accatttgga
     4681 tcttcataac gcatacgaga ataagataat gcctgatccc cgttcaaagt aattttaccg
     4741 attgtaaagt catagccatc ttgtgagaaa gtgaggtcat tattgacttc gataccacca
     4801 actgcatcaa caagttcttt tagccctttc atgttgatag agacatagtg atcgattggg
     4861 atgtctacat atttttgtac ggtatccatc gccatggcag ctccgccgaa tgcgtaagcg
     4921 tggttgatct tgtcttttgt gtcacgacct acgatgtcga catacgtatc tcgaggaatg
     4981 ctgacgatcg ttgtctgttt gtcttcagga ctgactgtgg caaccatcat cgtatctgat
     5041 cttccttgat cgacccgacc taaatctcca gtatcaatgc ccatcaatag aacagagaaa
     5101 gattcttgtt tgtccagatc aactggtttc gttcgttctc cttgggttcg ttccactgat
     5161 tcgtaagttt tctcaataga atgtgagaga tccagatata attttgctcc tactcctaca
     5221 attgctaata ctaatacgat aagaactgct aaaataatca gaaatatttt tttccctctt
     5281 gattttcttc ttcgtcttgc catagtttcc tccgtttgct aaccttgctt gaatcaacgt
     5341 tttaactgtc aatagcttat attgctatag cccatttgct gagcaacagt ttgtgctttt
     5401 gttgcgtatg ctgcgcgtat tttttcattc cggatctgat ctatttgact gagcaccgtc
     5461 aaatattgat cgtaagtagc ggtggcagtc acttgaccat ccttcaacat cgtatcgaat
     5521 aactgatcta gttgcgtgac ttgcgcgatc tgagtatcag cgaatcctag atattgcata
     5581 acaatcgttt tccaaggact atctttaaaa aagctcatat tttcacgtac acgagcgaca
     5641 tctgcacttg tcaccttttc tttgatgacg acatcgtcta cagcttgctg ccagtttgat
     5701 acatttttag taaataaatc gttgacagct gtctggatct tcagttttga ttctgcacta
     5761 tctaactgtg tcacgattgc tttcttctca tcttggattg caacagcttc tttaggcaat
     5821 tctgattctt tgatgtcgta atcatctgct gaaagtttga cagaggatag cttatttgac
     5881 aaacttgtga ttgtttcttc tgttatttca gggtttagaa aatttttttc ttttgtacta
     5941 tacagcttgt ctacttcttt tgataaagaa gtcaaggtgt ctttttgatt ggtgatggca
     6001 gattctgcat aattgatccg ttgctgatgt tgccgctgat tattgatatg gtaaccaaac
     6061 aaacagatcg caatagcacc tgcacctacc gccacagcag tcaatgactt gacgaatggc
     6121 ttttccatag attcactcct aagtattgat gatagataaa ttaagatata attcacttac
     6181 ataaaaatga cagcttttta ttttaaaaaa cataattaaa ctaatatatt cacagaaata
     6241 tttgtaaaca agttttccct atataatcat accacaaact gttttcttga ctagggcaat
     6301 ttacgattta aaaataaata aaacattaat aagataacaa ttaatcgatt tcattttta
//
LOCUS       DAZKCW010000104         6173 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000104 DAZKCW010000000
VERSION     DAZKCW010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.108"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            725..811
                     /locus_tag="ACG84Z_002624"
     CDS             725..811
                     /locus_tag="ACG84Z_002624"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFP9163419.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACG84Z_002625"
     CDS             complement(932..1621)
                     /locus_tag="ACG84Z_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163420.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="ACG84Z_002626"
     CDS             complement(1866..2780)
                     /locus_tag="ACG84Z_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFP9163421.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACG84Z_002627"
     CDS             complement(2762..3142)
                     /locus_tag="ACG84Z_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFP9163422.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACG84Z_002628"
     CDS             complement(3592..3879)
                     /locus_tag="ACG84Z_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFP9163423.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACG84Z_002629"
     CDS             complement(3899..4123)
                     /locus_tag="ACG84Z_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFP9163424.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="ACG84Z_002630"
     CDS             complement(4578..4748)
                     /locus_tag="ACG84Z_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163425.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="ACG84Z_002631"
     CDS             complement(4763..5296)
                     /locus_tag="ACG84Z_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFP9163426.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..>6173)
                     /locus_tag="ACG84Z_002632"
     CDS             complement(5317..>6173)
                     /locus_tag="ACG84Z_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFP9163427.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1632 a         1151 c         1042 g         2348 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga atgactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAZKCW010000105         6161 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000105 DAZKCW010000000
VERSION     DAZKCW010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.109"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..355
                     /locus_tag="ACG84Z_002633"
     CDS             <1..355
                     /locus_tag="ACG84Z_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163428.1"
                     /translation="GAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELL
                     RKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDT
                     EDSLRKGWGMNNKVR"
     gene            615..1076
                     /locus_tag="ACG84Z_002634"
     CDS             615..1076
                     /locus_tag="ACG84Z_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermophilic serine proteinase"
                     /protein_id="HFP9163429.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRTNESDYNKRDQVLL
                     VKLNEEISVEEAVRTFNASDMVNYAEPNYVVELEPLNDVEEPNTTDSLGNR"
     gene            1120..1206
                     /locus_tag="ACG84Z_002635"
                     /pseudo
     CDS             1120..1206
                     /locus_tag="ACG84Z_002635"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(1172..2242)
                     /locus_tag="ACG84Z_002636"
     CDS             complement(1172..2242)
                     /locus_tag="ACG84Z_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFP9163430.1"
                     /translation="MKNDIVTYANTKCEEIGISNLEECFFDTNDLSQFLRTGRTNASK
                     LANDLVAKNVLFKINTRPVLFAIKERFEEHFLIPVKDVYESISELKTDLEPNSTDSIL
                     QKMIGYDMSLSDAVEQMKTAVFYPGRGLPMMITGDTGVGKSFFVHTAYQFMKKVNVIH
                     ENAPFKVLNCAQYHNNPELLSGILFGYVKGAFTGADEDRNGLLQDADGGVLFLDEVHR
                     LPPEGQEKLFVYMDGGTYSRVGETIHHASNVRLVFATTEGKEDFLETFMRRIPIHIHI
                     PNIEERGILEKNKLSKILSLAKAKTLARLLMFLLKSLVLHKYSQNILNYYFLEKSKKN
                     RIPNFHLHFQKDLHVDNQFLNQ"
     gene            2844..4688
                     /locus_tag="ACG84Z_002637"
     CDS             2844..4688
                     /locus_tag="ACG84Z_002637"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFP9163431.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            4744..>6161
                     /locus_tag="ACG84Z_002638"
     CDS             4744..>6161
                     /locus_tag="ACG84Z_002638"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFP9163432.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSF"
BASE COUNT         2044 a          985 c         1247 g         1885 t
ORIGIN      
        1 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
       61 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      121 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      181 taaacaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      241 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      301 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      361 aaagaagaac taagtaacta cctttaaacg gtagttactt agttcttctt tgatttgcgt
      421 gaaatagagg ggatttattt ttctggttac gtgattaaaa aatccaaaaa atgagcatag
      481 gaacggttat gattttaggg tgtgttttaa tgagatattg tgatttcatt aataagtgta
      541 tgataatctg ttgttgagtt agtaaataag taatagagct aactctaaaa taaaactatt
      601 aggaggagat gtagatgaaa aagtttaaaa agaaaatata tttaggattg gttgttgggg
      661 tgagtatgtt tgggttcatg gctcatacta aacaagtaac tgcagatact aaccaaaaag
      721 aaaggattat gagccaatta gatgactctc aaatagagta tgtacccaat gagctaattg
      781 tcagtttaaa ggctacacaa agaatttcaa cagagaaaaa taaaccgcaa aatttattgg
      841 gtgtaaaagt tatggtggaa aaagatttga ctcttaggac aaatgaaagc gattataata
      901 agcgagatca agtattatta gtgaaattga acgaagaaat tagtgtggaa gaggcagtaa
      961 gaacatttaa tgcttctgat atggtcaatt atgcagagcc aaactatgtg gttgaactag
     1021 agccgttgaa tgatgttgag gagccaaata caactgattc tttaggaaat cgataacgat
     1081 cctaattgga gtaaacaagc taatttaaga gagattagca tgccatccgc ttgggaagaa
     1141 accaagggtt ctaaggatgt gaaggtagcg gtcattgatt caggaattga ttatcaacat
     1201 gaagatcttt ctggaaatgt agatgaaagt ttgggatacg atttttttta cttttttcaa
     1261 gaaaataata attcagaata ttctgactat atttatgcaa cactagtgac tttaggagaa
     1321 acatcaatag ccttgctaaa gtttttgctt tcgctaaaga gagtattttc gataatttgt
     1381 ttttttctaa aatacctcgt tcctcaatat ttgggatatg gatatgtata gggattcttc
     1441 gcataaaggt ttccagaaaa tcctctttgc cttctgtagt cgcaaaaact aaacgtacat
     1501 tggaggcgtg atggatagtt tcaccgactc tagaataagt tccgccatcc atataaacaa
     1561 atagtttctc ttgcccttca ggaggcaatc tgtgtacttc gtctaaaaac agtactccac
     1621 cgtctgcatc ttgcaacaat ccatttcgat cttcatctgc gccggtaaaa gcacctttaa
     1681 catagccaaa tagtatcccc gacaataatt caggattatt atggtattgc gcacaattaa
     1741 gtactttaaa aggagcattc tcatgaataa cgttcacttt tttcataaac tgataagcag
     1801 tatgaacaaa aaaacttttt ccaactccag tatctccagt gatcatcata ggaagccctc
     1861 ttccaggata gaagacagca gttttcattt gttccaccgc atcggataag ctcatatcat
     1921 acccaatcat cttttgtaga atggaatctg tagaattggg ctccaagtct gtttttaatt
     1981 cagatatact ttcgtataca tcttttaccg gaatcaaaaa gtgctcttca aagcgctctt
     2041 tgatggcaaa taacactgga cgagtattga ttttaaatag aacgttcttt gcaactaagt
     2101 cattggcaag tttactggca tttgttcttc ccgttcttaa aaattgcgac aggtcatttg
     2161 tgtcaaaaaa gcactcttct aaattactga tgccaatttc ttcacatttt gtgtttgcat
     2221 aagtcactat atcatttttc atcttataaa cagtcctttc taaacttcta tcccttaaat
     2281 aaatagcaaa aaaaaggaag caatatcgat atgctgtcct cttaatttaa taaagcgcta
     2341 atctaattca ctgtattatc attttttagt agtatagcac aattatgaat gccttttctt
     2401 tatatcaaat aaagtttata taaaaaacct catcctgcaa gaaagaaaaa atgaacccat
     2461 tctttttata ctaggtctta aaaagacaga acatctgcta gaagatagaa gagaataaga
     2521 gttatatatg ttggaagata ttcttagaaa aaagacaaaa cttttagaac acgaaaacta
     2581 tattgaacga ataaaatgaa aaaatgatta aaaaatcatt ttattattta cgtttacatt
     2641 ctaatatgtt aaattgaata taacttaaac aggcatgtga ctggtaatgc aggcaggacc
     2701 taaataagtt gaataacaat gtatgcgttt caatacacgt ttgccttgtt gtcaatttat
     2761 ttagtttctg cctgtttttt gtgttgagga tggccacttc gactcaaaag ttcatcactc
     2821 aaaaaagaaa agagggaaac accatgaatt acaaacaaac agcagaagaa gtattgcagt
     2881 acatcggtgg ggaagaaaac atatcccatt tggagcattg ctcaactcgt ttacgtttta
     2941 cgttaaaaga caacagcaag gtaaatatga gccagttaga aaaagtggat ggcgttatgg
     3001 gcgttcgcca aaatgtgcaa tgccaagtaa tcattggaaa cgatgttgtt gaagtgtatg
     3061 atgaagtgaa agcgttatta ggtgacaatg tttcaaatac tgaagaagca ccaaaacaaa
     3121 aacaaaaatt aggttcagtt ctattagatt ttattatttc tattttccaa cctttaattc
     3181 ctgcgattgc aggtggagga gtattgaagt ccttgttgct actagcttct atcttagggc
     3241 tgattagtga ccaatctcaa acctatcaga ttttaaattt ggtcggcggg gcaccgcttt
     3301 atttcttgcc tattctggtg gcaatgacta cggctaataa attgaaagtc aatcaattgg
     3361 ttgcagtatc tgctgtcggt gcattgatcc ttcctgaaat gacagctatg ttggcggaag
     3421 gtgctacatt cttatctttt ggattggata atatagcgta tgcatctcaa gtattcccag
     3481 ccatcttaac tgttttattt tatgctcaac ttgaaaaatg gtttacaaaa gtttcaccaa
     3541 aaccaattcg tattttcttt gtacctatga tgagcttatt gattacagtt cctattgctt
     3601 tgttgcttct aggaccatta ggttataatg taggaacagc tttctcttct atcattgtgt
     3661 ctttgtacaa tcaatttgga tgggttgcaa ccggagtctt agcagctgta ctgccattaa
     3721 tggttgtaac gggtatgcat aaagcaatga tcccttacgc tgtttcatcc atgagtgaat
     3781 tgggtgcaga acttctttat ctcccggctt cattggcaca caatatttca gaagctggcg
     3841 catgctttgc tgtcagtatc aaaacaaaag acaaaaaatt gaaatctacg gctgtttctg
     3901 cgggtatatc tgcattattc ggaattactg aaccagctct ttacggggta acgattctgc
     3961 acaaacgtgt tttatatgcc gttatgtttt ctagcctgat cgggggagca tttgcaggaa
     4021 tcgttgcact tcaagccttt gctttagtgg gtcctgggat tgcaagtatc acgatgttcg
     4081 ctgacaaagc tgacccaatg aatctggttt gggcatttgc agtatcgggg atttcatttg
     4141 tggttgcttt tgctgcagcg ttggttcttt ataaagataa agaagttgtc aatgaagttg
     4201 aaactaagat ggaaacggcc gttgtttcag atgctgttct ttcaagtccc gtgaatggaa
     4261 aagtaatctc actatcagaa gtaaaagaca ctgttttttc tagtggtatg gtaggtgatg
     4321 gagtagcaat cattcctgaa gaagggatat tagtagctcc tgaagatgga gaaatcacaa
     4381 tggtatttga aacgaagcat gctattggtt taaaaacggc taatggtgca gaacttcttt
     4441 ttcatattgg tattgatact gttcagttag aaggaaaagg gtttgaggca tttgttcgtt
     4501 ctggtgaaaa agtagccaaa ggacaaaagc tgattgcatt tgatattgat ttaatcaaag
     4561 aagcaggatt cgaccccaca gttatctgtg tggtaaccaa taaggataat tacactatcc
     4621 gttcatttaa cctagaaaaa ttggtaacca atgatagtga tctcttagct atcagtccga
     4681 tagcttaaac acaagatagt gaaaaaaaat atattgaatg aaggaataga ggagaataga
     4741 ataatgacaa acacaacaag ttttccaaaa ggatttttat ggggcggcgc gatagcagca
     4801 aatcaagtag aaggtgcttg gaatgtagac ggtaaaggtc tttcagtagc ggatatggct
     4861 acttataaac caaatttaga caacaaagat tttgctgctc atatgcatgt caccctgcag
     4921 tctataaaag aagctagtga agacaaatct gataaatggt acccaaaaag aaggggcgtt
     4981 gatttttatc atcactataa agaagattta gctttatttg ccgaaatggg ctttaaaacc
     5041 ttgcgcctct ctattgcttg gactcgcttg ttccctacag gagaagagct ggaaccgaat
     5101 gaaaaagggg ttgcatttta tgaaaacgtc tttaaagaaa tgcaacgttt aggaattgag
     5161 ccgattgtga cactatctca ttatgaaatg ccattagctt tagcagttaa atataatggc
     5221 tgggtggagc gtcgagtaat tgatgatttt gttcgcttcg ctaacgtttg ttttgatcgc
     5281 ttcggcaaat acgtaaaata ttggctgaca tttaatgaga tagacagcat ccaccgtcat
     5341 ccatttacaa cagctggaat tatccaagag aaaagcgcag aaggtcaaga agctcaagat
     5401 atctatcaag cattgcatca tcaatttgtt gcgagtgcgt tagtgacaaa agatgctcat
     5461 gaaaaaattc caggaagcca agttggttgt atgttaacga aattgatgac ttatccatta
     5521 acttgcgcac cagaagacgt tgagctgacc ttgaaaaaga acttagaaaa taatttttat
     5581 gcagatgttc aagttaaggg agaatatcct gctctaatcg aaaaggattt ggaaaatcgg
     5641 ggaattcaga ttaaaatgga agatgaagat cgagaaattt taaagaaaca taccgtagat
     5701 tttgtttctt tcagctatta catgtccatg gcagaatcag ctgatccaaa cgcagaacgc
     5761 acaccgggaa atactgtttt aggggttaag aatcctcatt tgccttcaac agattggggc
     5821 tggcaaatcg atccaaaagg tttgaaaatt tcgttgatcg aactttatga tcgttaccaa
     5881 gtaccgttga tgattgtgga aaatggtatg ggagcagtcg atcaggtagt agatggtaaa
     5941 atccatgatc cgtaccgcat cgactacttt aaagcacact tccaacaaat gaaagaagca
     6001 atcgatgaag gtgtagattt gatagcttat actagctggg gaccaattga tttagttagt
     6061 gcaggaactt ctcaaatgtc taaacgatat ggatttattt atgtggatgc agacgatgaa
     6121 ggaaatggga catataaccg cttgaaaaag gattcgttca a
//
LOCUS       DAZKCW010000106         6068 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000106 DAZKCW010000000
VERSION     DAZKCW010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.110"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            832..1566
                     /locus_tag="ACG84Z_002639"
     CDS             832..1566
                     /locus_tag="ACG84Z_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9163433.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="ACG84Z_002640"
     CDS             1582..2751
                     /locus_tag="ACG84Z_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9163434.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="ACG84Z_002641"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="ACG84Z_002641"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFP9163435.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="ACG84Z_002642"
     CDS             3841..4767
                     /locus_tag="ACG84Z_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HFP9163436.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="ACG84Z_002643"
     CDS             4786..6036
                     /locus_tag="ACG84Z_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFP9163437.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2027 a          997 c         1246 g         1798 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacaa caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agttaagt
//
LOCUS       DAZKCW010000107         6017 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000107 DAZKCW010000000
VERSION     DAZKCW010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.111"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(35..682)
                     /locus_tag="ACG84Z_002644"
     CDS             complement(35..682)
                     /locus_tag="ACG84Z_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFP9163438.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(690..1376)
                     /locus_tag="ACG84Z_002645"
     CDS             complement(690..1376)
                     /locus_tag="ACG84Z_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163439.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(1382..2455)
                     /locus_tag="ACG84Z_002646"
     CDS             complement(1382..2455)
                     /locus_tag="ACG84Z_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9163440.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            2677..3351
                     /locus_tag="ACG84Z_002647"
     CDS             2677..3351
                     /locus_tag="ACG84Z_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9163441.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            3356..4696
                     /locus_tag="ACG84Z_002648"
     CDS             3356..4696
                     /locus_tag="ACG84Z_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFP9163442.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(4845..5831)
                     /locus_tag="ACG84Z_002649"
     CDS             complement(4845..5831)
                     /locus_tag="ACG84Z_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFP9163443.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         1826 a         1134 c         1056 g         2001 t
ORIGIN      
        1 aaatttcagg acaaatacac atagctgttt ctttttattg tattccttca gcaatccaac
       61 gagatttata gcgaaagtct tttaacaact cttcttttgt ccaattattt gcaatgagat
      121 ccgtcaaagt gttcattacg agggtcatgg aaaagtatag gaaactaact gcttcttccg
      181 acgattgaat ggagaaatga ttgattctta ataattccag ccatttttcg ttcattggag
      241 aatcagccga tagttctcta cgtttggttg tctgctgatc atttcgctgg gttaacaagt
      301 ataacctttg ccaatagata ctttcgtgat ctaagtcgca gcaccactct aaatattttt
      361 cgatccccaa aaagaaatgt tgtttgtttt cgctaatgaa ttttaagata tcttgatgga
      421 ctatgtgaga actgcttttg atcgtataca aataagcatc ttccaaatct tgaaaatatt
      481 tataaaaagc accgcgcgac atccccatct tgtcaacgat ttctgagact ttgacttggc
      541 tgatgtgctg tgagcaaaat atctccagta ataggtcatc gattctctgt ttctttgcgt
      601 tcgataaatt gaaaaaagtt tcttttggca tccacatctc tcctttatct ctgattatac
      661 gtggatagcc cttcattgtc atgaaggatt cattccttct ttttctcttc ttctgtcaag
      721 tacccatctt ccattcgata aacgcgatca ctccattgaa tcatacggac atcatgagta
      781 accataatag tcgctttttg tttctcatga gcttctttaa ctagtaattt gacgacttca
      841 tatgcatgat ctgtatccaa actagctgtt ggttcgtctg ctaagatcaa gcttggctca
      901 ttatataaag cgcgagcaat tgccactctc tgtctttctc caccagaaag gtctttagga
      961 taactatttt taagtgactg gatatctaaa gattgcagca aggaatcgat ttttgttgaa
     1021 tcttcttttt ttgaagtaac ttggtcaact agttcaaatt gttcctttac cgttaaaaaa
     1081 ggaatcaaat tagagctttg gagaataaat cctatttctt taaagcgtaa atctgctcgt
     1141 tttttttctg gaagctcagt tagtgagtga ccgttgatca ctatttctcc ggaagtcggt
     1201 gtttgcaatc ctcctgaaat ggtaaggaaa gtacttttac ctgaaccaga aggaccaatg
     1261 atgctgacga attctccttc ctttacataa aaatcaattg ctttcaaagc tgagaccttt
     1321 gtatgaccag aaccaaatgt tttggtaact tttttcatcg ttaatatttt tttcattttt
     1381 attaacctcc tattgctgta attgggtcta ctttggttat cgtacgtatc gaaaacaatc
     1441 cgcctagcat tgcgacaatg atcaaaatcc cactatatag caaccattgt gaccaaaaaa
     1501 cagcaaaagg catcgcgctt ggtaaaatca gactagtcaa ataagcaaac aaaagagcaa
     1561 gcagaacgcc taccacccca acaataaagg actgtgctac taaagattta gcgatgaaga
     1621 aatttttgat cccttgtgct ttcattactc caaaaatagc agtcttctga agtgtcatca
     1681 cgtacatgaa aataccgacc acggcagcaa ccactaagaa caaaaagtat atcatcgcat
     1741 ttaaggtcat attttgggca gaatagccag gaatactttc aatgaatgtc ccaatagtta
     1801 ataactgtag acccttcgat gctttttctt tcgaaatttt agctgaatcc tttattacga
     1861 tcccattgat cggctgttct tcttcagaag caaacggctg ttgtccatac ttcaaagcag
     1921 tccacgtatc tagggacgca tagatgacgg gagaaactgt gtaataagtt tcaggaaaga
     1981 taccgacaat cgtcaaagga tcgtcgtaac tgccaatttt gatcgtatct ccaattttat
     2041 agcctgaatc agccagattt tgagagatga tgatttcatt ctttgtttta aattcatgcc
     2101 ctttcgtgag ttttggtaat aaaaatgctt ctttcgttgt gccgaaaact gtaacatttt
     2161 ctttgttttt tcctttgatt gctccgctgt acaatccgat tggtgctttc tctcctcctt
     2221 caatgtattt cagatctcct cttgttaatt gtgaagctgc aaatacttga tttgcatcct
     2281 ccgacaaaac aatctcttgt gcgtcccaat catcgattgc ttttttaaac tcttctgaaa
     2341 gtccattcgc tagtcctgac aacatgaata cgacatacgc aatcaagaac ataataccga
     2401 cgatcaagcc atatcgtaat ttagaatagc gaatttcttt gatagctaga aacatttgtt
     2461 tttcctccct atgatagatt gatagtgaca aaatgtcact tgttgaatag tgtaactcta
     2521 aagtgacaat ttgtcacttg tgttgttttt ttcttatcaa taaattgtct aagacatctt
     2581 tcgataaaac cttaacatga gtcataaaaa atttatttaa gccttattta tgctttccat
     2641 gataaactaa agtgaccaaa tcaatgaggt gggaaaatga ttaaactatt agtagtagaa
     2701 gacgataaag tattatccaa taatataaaa gaaatactcg ctgcaatcgg cgagataaca
     2761 caagtttatg atggtagtga aggactgttc gagttggaaa gtggagttta tgatcttgca
     2821 atcttggatt tgatgatgcc ggaaatgaat ggatatgaag tgttagcaaa aatacggaaa
     2881 gaaaaaatac agactccagt attgattttg actgcaaaag atagtttgga agataagatt
     2941 gaaggatttg aacgaggtgc agatgattat ctaacaaaac ctttctatcg agaagaactg
     3001 atcatgcgcg tgaaagcatt attgaaacgc tcgctaggtc tctttgatga aaatgttctg
     3061 aagtataagg atatcagttg tgatttaaaa agcaatgaag tcttgtataa agaacaagtt
     3121 ttgcccatac aaggaaaaga gtttgaattg ctcgtttatt ttttacaaaa taagggaatc
     3181 attttgacaa aagagcagat atttgaccgg atctggggat ttgattctga tacgacgatt
     3241 acagttattg aagtttatat gagcaactta cgaaaacatc tgcgaagtac tggattggat
     3301 aaagaaatca aaaccttacg taatgtcggt tatatactgc aaagggtgtg atgcaatgaa
     3361 tggagatatt acacgaaagc aacgtagtcg cttttttgcg acaaatgtag cagcatttgc
     3421 ttttatcttt tttcttttgg gattcattac tttacagata ttaaaccaat ctgcatacag
     3481 agaaacagat ctgtcattag agaaaataaa ttttgattct cgaacagtac aattagagat
     3541 acaaagatat cagcaaggcg atcccttttt aaacccgact caaacggaac aaaacagaac
     3601 aaacatggaa cagccattaa tggaaccatc aaatgaccgt tttaacactc aagtgatctt
     3661 gtggtctaaa aatggtgaga tattgaataa agcagctatt ggtgggcgtt tcaaccaaat
     3721 caaagaatta aaaatggata cgaaaaatct gaataccatc caaaatattg aattaaatga
     3781 agacagtggc tcatctgccc tctctttccg ttcgattacg aaaaaagcgg agacgaatca
     3841 agatggcgtt gcctacatcc aaattttaga aaatacaaat caaatcaaga attcattagc
     3901 gacttttcgc acgattatga ttttgtgtat gattgttttt tggattctct ctattggtat
     3961 cagttattac ttgtctagtc taagcatgcg ccctattatt ctttcttgga gaagacaaaa
     4021 agaatttgtt gagaatgctt ctcatgaatt gcgcacaccg ttaacgatta ttcaaaatag
     4081 tttggaacat ctttttacca agcctaatca tactattatt gaagaatccg aaagcatcgc
     4141 tcaagcattg tcagagacga ggcgcctcac tggattgact tcggatttgc tgacaatcgc
     4201 tcggaatgat tctgatcagc agctgctttc aaagcaaatg atcaatacac aagaatatat
     4261 cgaacaactt gttaaaccat ttcaagagat ggccatcata gatggaaaag agtttattct
     4321 ccataacgat gcaacattag aagtaccaat tgatgaaaaa aaaatccatc aagttttggt
     4381 tattttgctg gataatgcat taaaatatac gaatccagaa gataagatca ttttggattc
     4441 atctgttaac cataaagaat ggctgattca cgtaaagaat actggccctt ctatcagtga
     4501 agaagatcaa gcaaggattt ttgatcgatt ttatcgggaa gatcaatctc gggcgaaaga
     4561 gactggcgga tacgggcttg gcttggcaat tgcaaaacag gtaatcgaac agcatcatgg
     4621 acagatttct gtatccaatt atcttccaca aggagtcgat tttaaagtcc aattgccgtt
     4681 gaagcctaaa aaataatgct tatccctaaa aaagggctgt gacaaaaatc ttgtcacagc
     4741 ccttttttgt tgcgaataaa cggtgttcca gaagtagctt cttcggaaat aagccgaaat
     4801 ttctttaagc tgaccacttc tgtcacaacc tctttagctt acgcttacga ttttttattg
     4861 cggtcttcaa tgtgtacatc accgcttgtg tcaatatcca attcttctcg gctaacatct
     4921 tctgtcactt tttcaacatc ttcatgttct tctttatgaa tcccaacttc ttcacgaata
     4981 actgtatgtt tgcttacatc tacttgctct tctttgattg ggatagtaat cgtgtcatct
     5041 tccaattttt cgtctgttcc ctgtgaagat tgatctgtta ctggtttgcg ttcgatgacg
     5101 atttcttcac gtttgaccgg tacttctacc gtttcagtat cgttgaccac atgtttgtgg
     5161 atgtcgactt ctccagttgt cacatcatgt gtatttacat ctaatttttc ttcttttagt
     5221 tgaattgtat catcatctag atttggtttg cgatcgatgt cttcagtctt gcttgtaccc
     5281 attgtatcag tctcgccagg tacgtccatc ggatcagttc ctggtgtcat attcaatgga
     5341 tccgttgtat tttgaaagcc tgtcgtgcca cctacgtcca ttggatctgt tccagtgcca
     5401 gtttctaatc cagtccccat tgtgcttgct gggctaacag tatcttgtgt atccattgta
     5461 tcttctgttg tttctggctg acgatagcct tttactgtga tgacaaattt tccatcagaa
     5521 atatctcctc tatattgata taaaggatca ttttctggtg tagccgtctc agaatcatag
     5581 gtatcaaaag aaaaagtatc ttttattttt tcccataaag aacggtcttc ttcaccatcc
     5641 atccgatttt catctgtttc aacatctata ccagacaatc cgtcaaatcc tagtctagat
     5701 gctgcttcat cagtagtata aataacgata tcatctcgtt catacccttc gttacgcaac
     5761 cgttcaatta ctgataatgc ttcttccctc gtactatagc ttccgatgac cgttaaattt
     5821 ttctcttcca tgtaaattcc tcctagcaaa tagatttatg attggtatat tgttacttat
     5881 aaatttattc tataggagac gattgttttc tacaaatatt tagattggaa tttgattaaa
     5941 acaatttaat tgaaatttga aaacatttat gttaatgaaa gtcatattct aataaaatgt
     6001 catttgtttc tatatga
//
LOCUS       DAZKCW010000108         5985 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000108 DAZKCW010000000
VERSION     DAZKCW010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.112"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(480..983)
                     /locus_tag="ACG84Z_002650"
     CDS             complement(480..983)
                     /locus_tag="ACG84Z_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFP9163444.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1342..2367
                     /locus_tag="ACG84Z_002651"
     CDS             1342..2367
                     /locus_tag="ACG84Z_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFP9163445.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2690..3568
                     /locus_tag="ACG84Z_002652"
     CDS             2690..3568
                     /locus_tag="ACG84Z_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFP9163446.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            4044..4160
                     /locus_tag="ACG84Z_002653"
     CDS             4044..4160
                     /locus_tag="ACG84Z_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFP9163447.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            5088..5426
                     /locus_tag="ACG84Z_002654"
     CDS             5088..5426
                     /locus_tag="ACG84Z_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163448.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5520..5750
                     /locus_tag="ACG84Z_002655"
     CDS             5520..5750
                     /locus_tag="ACG84Z_002655"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFP9163449.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
BASE COUNT         2027 a          895 c         1094 g         1969 t
ORIGIN      
        1 ataacgacac agaaaatacc gtgtctcaga tttctctact acttctaaaa actactgttt
       61 ttttcctttg aaatgccttc aaaaagtagg atcaggcaga atatactggc agaatcaagg
      121 agaagggagc ctaaataagg agaaaaacca tagaaaatat aaagtaatta cttataaaac
      181 aagcttttta tagaaaaata atatacctga gtagggtata aattaagacg gaattccttt
      241 ctagattgag atattgacta ggaagaatgt taagatttta agcctttaag ctaaaaaaaa
      301 accctttttg ttaaataagg ggaatatagc ctgtcagttt caaactgcaa gtcgtcctgc
      361 tgcaataata tagtagatta gagatgaaaa tagatttttt taaaccaatg actgaataaa
      421 aagaccgtca tagatacaca ttggaatgtg tctattacgg tcttttttta cgaacgattt
      481 tattgaagac ggacagttcg ggtcaaaaat aaaaaagcta cgatcagaaa taagaataaa
      541 atgtatccca aaataatggc tagacggtct aacttatttg tcgatagatg tttgtttaga
      601 agttgatagg cccataaacc tatcagtcct cctgttgtat tagttatcaa atcagtgatg
      661 tccgctacgc caataccgaa taggaattga atcaattctg ccaagaagct tacaaggaaa
      721 ataatcccta attttttaga aaaagaaagt ctcttgaaat tgacattcaa aagcacccca
      781 aaaggaaaaa agacaatcaa gttataagtg gtctcacgta ataccgtcgt attttcaaaa
      841 gaaaaagtag aaaaagggac gagattgaca ttgctgtaag aataagtgag aaattgtgga
      901 agattaaatg atagcttgaa taaaatcaac cataatagaa agaataaata aatccctaat
      961 aaaaattttg atacataccg catagacatc tcctccattt aaaaagtata ccatcgaaaa
     1021 ccgctgaaaa atcataaaaa agtatgaagt ttaaggacca acgtagttat cgtacgaaaa
     1081 ttagaagctt ttttttgttg ggaatccggt ttctttaaca aagctaagat agcgagttgc
     1141 ttggaaaagt tgctatcttt tttctgtcaa aacgactcgg aatgttcgtt ttttgttcta
     1201 atttctccaa gttgtttact ttttgatact aagtttatga aaaatcaaga aatagttgtt
     1261 atactaggta atgctgacaa acgggattgg catttcatct tggttcagct ttttttccaa
     1321 ttactaggaa ggagggatag attgttcaag acttattttc gtttcaataa aatacaagat
     1381 aatccttttc gtatcatgaa tctgatgcta cttatcttta ttgtattatg gttaggttac
     1441 ataaatcatg attttttgat ttcaagtttt tcatcattag ggatctttac ttttttctat
     1501 tatcaaaaca taccgatgaa atatttgctg aaacgtatgt ttctgatcgg ttgcggactg
     1561 ttggttgctt tcgttttggg gatcttatcg acttatgttt tatggcttga accatttgcc
     1621 gtagctttgg ttgctttttc cagcagattc gtgttgcgat tattccatat ttctaaacca
     1681 ggtggcttgt tttttgcgat gctttctgcc atgggaacga gcatgcagct gccaatcgct
     1741 caattaccga tcgtctcact ttattttttt atgggtgtcg tttttgccct gattgcggca
     1801 gtgattacaa aattactgga ttcacggcct gagcagacaa ttgaaaaagc aactttaaaa
     1861 gaaagatttc acgaagagcc tttagtgatc attgattctg ttttctacag cgctgcctta
     1921 tttctttccg tttatgtcag tcacggcttg aatctgcata atccttattg gttgaccttg
     1981 tcatgtgcat cgattttgct agcagaaaac ttggatgcga tgaagcatcg acaagtccaa
     2041 tatctgattg gatcgatggg tgggttatgt gtgtcggcat tcttgtcatt tgtgccgttt
     2101 acgcagttgc agaccatttt tctgatcact tttctatatg gaatcgcaca atttctagtt
     2161 gctagaaatt atgcagttgc taatattttt cttaatccga tggcgttgat gctatctaca
     2221 cttattcgtg gagcatactt gatttctttg atcgaatatc gttttttagg gatcgtcata
     2281 ggaagtttca tcggtttagg tgttgcgtgg gtaatgacgg ttggtttgca acattattta
     2341 acggttgttc gtcaaaaatt agaatagaag gacaaatata tgtgccaaaa gaggttatga
     2401 caagattttt gtcacaacct ctaattcaag gtgttcaaaa gccagattct cagcattaag
     2461 tcaaattcac acaaaaatgt ggaaaggaac tttcaaaaaa attttatatt tattctatca
     2521 aaaaattttg tttatgatgg taactgaata aactttcctg agatggtcaa tgctttcctt
     2581 gaaagtctta cagatattct ttcttcatag aaagtttaag ttttatagtt agtgtacaat
     2641 aaaagtatgt ttataccata tggtgtccgg ataatcagtc atttaaacaa tgaggttcaa
     2701 agatatgaaa aggggaaatt tgatgaagaa aataagcaat gaaatccaaa ttctggcaga
     2761 aactttaact cttcccaaag tcgttataga gcaaatgatt gtacaagcaa aaaacatcct
     2821 tgatgaggtg tttgagcaat atagtcatga actaatggat cctaataaag caaaggcgac
     2881 tgcaaagaaa atagacaaag tctatgaaga ggaacctttt gcagcattag ctatttatct
     2941 atatgcagct tctcaaagtt ggaaaaaaat ttatcaacca ttgaagattc caagaactat
     3001 ctatttggca acaatgaatg cttttactag atttattcat gaacatttcc aagtaacagg
     3061 aagctatcgc tttgaccgtg gtttttggat ttggcattac actagtggct tgatctttcg
     3121 gattggtgaa ttggagtacg aaatgacata ttttccgaaa gggtacacgg atctaagatt
     3181 agaaggaaag cagtgccttt ctcttcatat tccttccgat gcagatttat ctcagaataa
     3241 gataagagat agttacgaaa gtgccattcg tttttttgaa ctttattttc ctgattacca
     3301 ttaccaagtg atgtacacag atacttggtt actatcaccc aatcttacta aatggttgaa
     3361 aaaagagtca aaaatctgtc tttttgcagc cgattatcga ttattatcag ttgatgaaca
     3421 ggacgatagt ggagtccctt ggatctttgg acgagtagat gcccaaatac atgattatcc
     3481 agaaagtacg agtttacagc gacaagcaaa agagcaattg cttgcaggcg agcacattgg
     3541 ctctggctta ggtattctta cttcataagt ttagtacttc gaaatagttt aaaagagcgt
     3601 gagacaaaag taaagaacac ttttgtctca cgctctaaac acgtataaac ggcggaagca
     3661 gaagcaactc cttcggaaat aagctgaaat tcacaaaaat ttgaaaagca attttcgtga
     3721 atttcttctt gtttcttgga gttaaacgct tctgtcccag cctctttttt agtgttctat
     3781 cgaacacaca gtacgttcaa taggtaaact agctataaca atagatatta aagttaacgg
     3841 acaagagggc cttttttagg tagctaaaac gtaataatga aaatttattt ccagagatag
     3901 gagtcaatca gctagtctga tcgactgttt taacaagttg actttcattt taacttttga
     3961 taccatttaa aacacaaatc gtaattgttt cgatttgtgt tttttagcat gactacaatc
     4021 aaagaagaaa gtgggtcgtc catatggaaa aaacagatat ctcaagtgca taccgccgct
     4081 tgaaaagccc aaatatcaaa acacgaaaac gtgcgctgaa gatcatcaaa gatgtgaaac
     4141 ggaatagtgg gaaaaggtaa gaagaaggaa acttaattaa aaaaatagcc gaaaaacgtt
     4201 tttcggctat tttcaataat cggtttttgt gtaaggtttc cgaaagaact gctgttgatt
     4261 ttccattttt aacatatgat aaattggtag aatctttctt ttcaaattga taccattccc
     4321 taattccagt tatatagtta actacagaac cacaaagcac gtacgtttat aaaagtatta
     4381 tctgtagtta tttttcaatt ccctttcaac ctcttatttt gaccagtagt attgatcact
     4441 ttacctttta acacctttgt tcgtttttga aacattttta gtcaagaatg gaaacgtaac
     4501 tacataatca aaggttttgc gaaatatttc atgaaatatt tcatgtagaa gcgagcaata
     4561 cggttgcaaa taaccattat cgtttaataa gcagttacga aagctcccaa tatctctaac
     4621 gttcagctca ctccatttct tttcttcaaa aaaatcagtg attcgtatct ctttctattt
     4681 gtcgaaaaag ttaactttaa aaagtaacgc cgaaaaaata tgcaaaaaaa taaaaaagca
     4741 gttactattg ctagaataac atcaaggaat aataagtttt ggttttcaga taatagtcga
     4801 taagttgtgt attggaattt tagatacagt aataaagtat ttttcatgaa attttgtgag
     4861 aatcactatt acaagtatct ttaataaaat taatggttaa ggaggaactt aaagtagaat
     4921 gtaaatgaat agttgtagtc agtcgattgt gatactagac tcaaagttgc aggaataagt
     4981 ttttcaattt gtgattggaa gataaaaaat gaaaaagaag ggcttttttt tatactttgt
     5041 tgattgtagt gtttattttc cctctgttta gccaagtaac attttctatg actcaaccag
     5101 tttcaagtga ggaacatgat aacctttttc gtgctacaga agagtttaag aaatatcagg
     5161 aaaatattgt tccggagact ccattagcta gtgagccaat tactgatatt gatggaaacc
     5221 aaataggatg gtatatacag tacgaagtta tggtggtaaa taatgactca atagtaaaaa
     5281 atacagtagg cttagagcta acaccgattg aaaaggtgag ttcattgtta acgtatattt
     5341 atactgatga aagtgacgag actgagatca ttttaacgga ttactcaaaa attgctactg
     5401 ataaaaagta tatattgtgg atgtagacac tagtgaaata ctttatgata tagaaattga
     5461 tgaaaattta ctagatgtag cacaagaaat cgatcatcaa aagcaggaag ctattcgata
     5521 tgctggtaga aaagggaaaa gaaaatattt attacgtgaa tgtagcaaaa gttagagaag
     5581 atgaaaatga gtggaaagaa ttcaagagtc gctactcaat taactcgact ccgacattta
     5641 cagtttacag agaaggatcg atagaaaaaa ctgttttttg gactaaagaa agtggaatgt
     5701 ctttagctga agtagaagag tttttggatt atgttagtat gcaacagtaa gggagttctt
     5761 attatgaaaa attttgacac atattatgtt attgtttttt cgatatcttt gctgttaata
     5821 ttactaactt taatgcagta taaagagtat ccagagtatt ttattttaac ttttgtatat
     5881 ttagtaagta gctacacact tctatataaa ttcagaagtt cttctagagt ttctaaagtt
     5941 tgtttcttaa ttagcttatt gattctataa tatttttgat ttata
//
LOCUS       DAZKCW010000109         5778 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000109 DAZKCW010000000
VERSION     DAZKCW010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.113"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..666
                     /locus_tag="ACG84Z_002656"
     CDS             <1..666
                     /locus_tag="ACG84Z_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163450.1"
                     /translation="VAYYLLSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQFIRQN
                     LTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMYLFEVG
                     FILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHTSIHEV
                     TVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKPYVLGK
                     VVI"
     gene            710..979
                     /locus_tag="ACG84Z_002657"
     CDS             710..979
                     /locus_tag="ACG84Z_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163451.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1211..1507
                     /locus_tag="ACG84Z_002658"
     CDS             1211..1507
                     /locus_tag="ACG84Z_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163452.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1509..1931
                     /locus_tag="ACG84Z_002659"
     CDS             1509..1931
                     /locus_tag="ACG84Z_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163453.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1950..3542
                     /gene="mobP2"
                     /locus_tag="ACG84Z_002660"
     CDS             1950..3542
                     /gene="mobP2"
                     /locus_tag="ACG84Z_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFP9163454.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            3563..3883
                     /locus_tag="ACG84Z_002661"
                     /pseudo
     CDS             3563..3883
                     /locus_tag="ACG84Z_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4044..5185)
                     /locus_tag="ACG84Z_002662"
     CDS             complement(join(4044..4957,4957..5185))
                     /locus_tag="ACG84Z_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFP9163455.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            5433..5627
                     /locus_tag="ACG84Z_002663"
     CDS             5433..5627
                     /locus_tag="ACG84Z_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163456.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
BASE COUNT         2034 a          913 c         1158 g         1673 t
ORIGIN      
        1 gtggcctatt acttgttaag tgagccaaaa cagatcgcgg cgtcaaatat tttcacggca
       61 gtaatgacat taatgtgtgt catgtgcttt tctattttta gttacttact cgtccaattt
      121 atcaggcaaa atttaacaat gagtaaactt ttcaaaagtt tattggactt acttatctta
      181 ggcagtatgt taacgactct aacagatcgg ttcgaacaat ctgaaaaaac ggtagagggg
      241 ataaagaact tcttaacgac gattgatcaa tttataaatg gatatatgta tttgtttgaa
      301 gtaggcttta ttctcacttt gtttggttgt gtatttataa aactcattaa aagatcaatc
      361 gaaaaagaaa tggttattga tctaattccg acgctgagcg gctatgagta ttacgttgat
      421 tttggaaagt atgaggagtt gatccatacg gatatcgttc acacgagtat ccatgaagta
      481 accgttaagg gcatcagatc tactttaaaa gatggacagg agacgaaaac aatcgaccga
      541 agaaaagagg tctacaattt ttataaagtt gaagcaagtc tacgatatgg cattgggaaa
      601 ttgaggttag atgggagtaa tattcaacaa aacaaaccat atgttttagg aaaagtggtg
      661 atttagaact tcctatgaaa gatgaataaa taaggagaat cttttgaaaa tgattcttct
      721 ttacagaatt gtgcttatag ttggcacgga gttaaaaatc ttaaagaagg agcagttatt
      781 caaagtgaaa gaacatcata atcagttact atgtattaaa acgggtacga tgaacattca
      841 ataccgaaca gaatatttag aattaacgaa tcaaactgat tttttgtcga ttcgagagca
      901 acataagcaa gaaaaattaa tggctactta tagccaattg attgatgagt gggaacaatt
      961 caaggaatct aaaacataaa attccattta aacaccttat tttttaaaga gcataaggaa
     1021 acgtgacccc acttttaaaa aaagtggttg gataggctgt gcctatcacg tttctgaaaa
     1081 aaataaatga ccccaaaata ccaatatata ggatagtaca aggatagcaa aggatagtaa
     1141 aaggatagag gtaggatagc gaaaaggata ggatcctttt cactatccta tattatattg
     1201 gaggatattt atgaatgtta aaattagaga tttagatcca aaattcattt ctgaaattga
     1261 tcgaagatgc gttgaactaa gtaatcgtac aggaaataaa tggagtcgta atgattattt
     1321 aaagctactc gttgaaaatg attttgatcg tcctttgatg gaatacaaac aagaaaagtt
     1381 tgaccagtta ttagaaaagt tttcagaaat tcaaagttat aacacaaaga tattagaaga
     1441 atatgttagc caaaataatc gtattataga aatcttgatt gagcaaaata gaggaagtga
     1501 actttgatat ggcaaaggtt atagacaaac acatttactt tcaccaaaca catatcgatg
     1561 tattggatga aactatttct actcatgcag aggttaaaaa ctatagtgaa gctgttcgct
     1621 ttttatgtat gaactatgat ccagaagtgg agaaaaaagt aaattccaat caagcaaagt
     1681 tgaatggaat gagtaaagaa atttctattt taaccgaaat ggtttcagaa tttgcggatc
     1741 ttcatttgaa agatacagga atattaattg gtaaaaattc aactgtttat caagaagcaa
     1801 aagaacgagt ggaaggaaaa attaaatcca atcaaacaaa aaaatattcc cctcagttga
     1861 agaaacctgt gaatgaatct gttcatgcca gagtagatcc atttgatcca acgaagattc
     1921 taaaaagata aaaatgaagg aggataataa tgactcaatc gccttcagtt attctcactt
     1981 gtcaatttac tttgccgaat aaaaagtcat tttctactta tattgactat attacaaggg
     2041 aacaggctct tgaagaaaag gaacgacgta cgcccgaaga agaacaggaa cttcaacgaa
     2101 tcaagaatgc tttagaggag ttttatattc ctgaaggaga aactttttcg gagagtaaga
     2161 cgggtaaaga attcagtgaa acgtcgaatg aagctcaatc gttgatggaa catggaatca
     2221 attttgacaa gttagaggaa caagatttta ccaattatct ttcttatatg acacgtcact
     2281 atgcgttaga acaaaagaaa gaactgacgc aaagtgaaca aaaagaatac caacgcttga
     2341 accaagcaat gaaaaaatat caaacagaac cccataaaaa agcttcagga aatcttcctg
     2401 gagttttttc tatagcttca gacgaagtga aaggaagtga tctgaaggag attaagcaaa
     2461 tcttccaaag aggacaacaa aaaggctcaa tcatttatca agatgttgtt tctcatgata
     2521 attcgtatct tgaaaaaata ggattgtacg atcccaaaac agatacttta gatgaagaag
     2581 ggttaaaagc agctggaaga aaaatgatgg agacattatt cgagaaagaa caattgaatg
     2641 aaacaggtta ctggatggca acgattcacc gtaacactaa acatatccat attcattttg
     2701 cagttgttga aaaagaaaat acgcgtaaac cttacacgga ggttgaaaat ggtgtgagtt
     2761 atatcgtacc gaaaggtaag agaagacaag caacattaga cgcaatgaag accaattatg
     2821 tacatgagtt agaacgtttt tcttatgaaa aggatcgaat gattggtatg gagaaacgaa
     2881 atttattgac gcggaaaagt gatttgcgta acaccttaac aaaagtggta aaagagccag
     2941 cgcgttacga tcgacacgcg atgaacttat taaatgaagt atataaaacc ctacctgaca
     3001 aacgttcgga atggaattac ggggatgaaa aacgaaccaa actttcacca tacacaagag
     3061 agaaactcga tgagttaacc aaatatgttt taacaaaaga acctgaatat caagaatata
     3121 tacagatttc aaaagcattg aaagaagaag caaaaagtct ttatggggaa agcaagagag
     3181 aatcaaagga tgcagagaaa aatgctctct ttgatttaaa aaagcgcaca ggaaatgcca
     3241 tcctaacaga gctgaagaga caggatagtc aaataaaacc attaatagaa agtgttgatc
     3301 agatgcaatc tatttacaat gaacgatcct ttcgaacgct taaacaattg ccaacgaatg
     3361 aatacaaata tagttacgaa gaattcatga agcgcaggaa acaattccaa caaagagttg
     3421 tcacgcagcg gagtttgcgt caattaaatc gaacgattaa tgcccatgaa gaaaaatacc
     3481 acgcaagtaa agcatacgaa gagcaacaac gaagaattca aatggaacaa gaaagacagt
     3541 aaagacagta ggaggaatag caatgaaaca atatttagat caatggaaag ttatagaagg
     3601 atcattaaga gaagaacgaa tcgaacaact tcctgattgt ttagaaaaag agcatttgtt
     3661 ccagataaga gaaatgttga gaaacgaaca gtttgatcca aatcaatttt tagtcgttga
     3721 gtacccagct actggtgtgt attgttgtaa tcatgtgaat ggtgaaaaat attttatcat
     3781 tcaagaatat gagggcaagt tagcacctta ttatactact tgggaaatga atgaagaggg
     3841 aatcaataac tttccatgta aaagcattgg atttgagtca atacctcgga cacgatttgt
     3901 gagaattttt tcgagattcc agcgggtgag tatctcatcg tttcgaccag cggtcaaacc
     3961 aaaaccgttt gaccgctgat cgaagcgatg aagttgaaac cctgtggaaa tctcgccaaa
     4021 aaaatgtaag tggtagctag gaactaagct tgcaatgcca actcctccat ctgatttggt
     4081 gttaaatagt tgatactact atggattcgc ttgcgattgt aaaatccttc aatgtattga
     4141 aataacgcta aataagcagc ttcaaagttt tcatacgctt ttgatggata gacttcttct
     4201 tttttgagtg aggcgtgaaa cgattcgata ccggcattat cgtagggaca gcccttacga
     4261 ctgaaggagt gccgaatgtt caattcattc agctttgcct cataggcttc gctagtgtac
     4321 tgagaaccca aatctgagtg gatgatcaag ttctcggagg gtgtttggtt taagagcgca
     4381 ttgtcaaggg tttcgataac caattctttc gtcatctgct tgccaaactt ccaaccgatg
     4441 actttctttg tgtggaggtc ttgaatagtg gagaggtagg tccagccatc ttttagggta
     4501 tgaatatagg taatatctgt cacccatttt tgattgatcg acgtagtggt aaaatcttgg
     4561 tttaacaggt ttttacgtcc ttcactttta actttcgctt gtttgccagg cttgtacttc
     4621 ttgagggtga ctgaacgcaa gcctaatttt ctcatcagta tttgtacttt ctttaaggac
     4681 aaggtctcgc cacggccaac aagaatctta tgaattttag gcgcaccata gatacccttg
     4741 ttttcaaagt agattcctga aatcaagcgg tttaagcgtt tgttttctga ttggcgcttg
     4801 gaaggtttct ttttcttcca gtcatagtag ctggatttcg gtgcttccaa aacggtacac
     4861 atttgtttta cgtcatgatc atgaacattt gattgaataa attcgaagac atcactcatt
     4921 tttacttttg agcgaatatg gttaaagcct tttttaggat agtgttttcc tcctgcatgc
     4981 gggccatttc ctttttcatc gctaggattt ctgcctcagt catgccggtt gctacattct
     5041 ttgtatgaag cttcttccaa cgataaatcg tttgtgtagc gataccatat tgcgctgcca
     5101 gttcttcgac cgattggcca gactggttta aatctaagat catcttctta aagtcttcat
     5161 caaatttttt cttggctttt gccatcgtgg acacgtcctt ttcttagtag ttagattcta
     5221 ccaaatcgtg tccatgaaat catcctaaca tcacattgaa gagtccattt cactcacaga
     5281 gtgttagttg ttaagtgaat aaaagaagta aaagagtcct gaacgtgatt gtccaggact
     5341 ctttttttca atgaattgtt ttccgccaac tcattgagtg gtgcgatttg cgactacatt
     5401 atatcaaaag aaagagaagg gaggaagcag aaatggttca ttcaacgatt ggagttgttg
     5461 ttgaaaaaag cagagacaat ctcgtttttg tgacagaaat tcaaacaggc agatcttttg
     5521 tcgtcacaga caaagcggca aaagcttatc aaagtagcga tattttaacg ttaaatctga
     5581 ctacgaagac gttcgtcgat gcgacagaag attatccatt tgtttagtct aatggtgata
     5641 agtcaagatg aaatttaaga ttttctttat tgagtaatat gttttgaagc gcacgaaact
     5701 agacccgatc aaaatcaaat ttttttcggg ttgattcaag gatttgcgtc aataacggat
     5761 tgttatttct ctatcaca
//
LOCUS       DAZKCW010000110         5244 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000110 DAZKCW010000000
VERSION     DAZKCW010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.114"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1273..1938)
                     /locus_tag="ACG84Z_002664"
     CDS             complement(1273..1938)
                     /locus_tag="ACG84Z_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163457.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2064..4100
                     /locus_tag="ACG84Z_002665"
     CDS             2064..4100
                     /locus_tag="ACG84Z_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFP9163458.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4104..4742
                     /locus_tag="ACG84Z_002666"
     CDS             4104..4742
                     /locus_tag="ACG84Z_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163459.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4770..5198
                     /locus_tag="ACG84Z_002667"
     CDS             4770..5198
                     /locus_tag="ACG84Z_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163460.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
BASE COUNT         1730 a          802 c          958 g         1754 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgaggacta cctgtattag tcctcttttt
       61 tgaccagatt ttgaccagtc tattttacat tctaatatat tcatatgagc taattttatg
      121 attaaatggt aagtgtttcc ttgtttgttt tagtttaaac tagtgtgtaa tttaaaaatc
      181 tatatggaag ggtctgtggg gtaatactta aataaaggct aggaacctga taacatcaag
      241 gttcctagcc tttttataat aaaatgaagc gaaaataatt tcttttaaag agccgagatt
      301 atcagctata taagagtgaa tttgatgcaa aaaacagagc cgaaacagtc ttggtgttcg
      361 tagctctgct tatatgtttc gaatttaaga caaagagttg gcaaaagatg ttgataagga
      421 agataagata actgtgttat ataaactagg taactaactg taacaagcta attttaagag
      481 attcttatta gaagacgttt aggaatataa ctaagaaaat gattatacag gtaattgtca
      541 tttcaataat gttttctaat tttcgcgtct ttgttttaag aaaaaggcca gaatcagttg
      601 gaaaaaagtt cgtacgatag tgaagagggg caaaatttcc tactaatatt cccactaaca
      661 agagataaaa cggccaggtt ggtgtgattc ctctataaaa aaatgcccat gctaccgaaa
      721 tcccatagat taacaactga acaattttta caatgaaaaa attgttctgc cattactcaa
      781 agtctcttcc tccttgtatc gtttatttgt ttcattttat cattatgata ggcgcttgaa
      841 caatccattt tgtattttat tgagtactct tggataaact accagcgatt atcatattta
      901 tttatgttac tgtaagccat catataaaag taaatgagca gatcatagaa atataaaaaa
      961 gaactaaaat tgatctaaat tatgtgcagc ttgactacgt accaatctat attacttact
     1021 agattggtcg ttaatctatt cggatcgaat gagcaaaata tttttgtgaa tgtccatcct
     1081 tgattatgat tccaaaaaga atcattggga ggctgtggcg taaatattat actataagcc
     1141 agaaatacct atcattctga acttttttat ttaggaactt tcatctcaag gctttttcaa
     1201 ttaatttgta cccctgtttt ttggataaga tcatgtgcat tgattttttc tatctctacg
     1261 ttcatctcct acttaatgcc tatctggctc ctgagggctt ctttttaagg cgtcgtcata
     1321 gtcttggctg aggatttctt ggtaatctga gggaatggct tcccaagtga gcaggcgaac
     1381 gttcatgacg tgttttcctt tgtgtttgat tacagcatgg tttttctctt tttctacctc
     1441 tccagcgtga aaagacagcc atgtaccatg gccaaagata tcattacata cccaacgttc
     1501 gatggaattg tccacgtatc ctacagggag tgtggtatag ccgatttgtg gtttcaaaaa
     1561 aggattgaat cgatcgatcg tttcattttt gtattgataa ttgataagaa aaagatagac
     1621 caaacaaaag acgagcagaa agaaagatag tgtctttttg agtgagaagg gttgttttga
     1681 tgaataagat ttcttgttaa caagaggttc atctggcaat gttggttcta ttgattcggt
     1741 agctgattca atagaaggaa aatcaatcgg cagacctaaa gtatgatgta aaagtgacag
     1801 catttcaagg tctggcattg tacgagaatt ttcccaacta gaaatcgttt tatcggaaac
     1861 accaattttt tcgcctaatt ctttttgcgt aagcttacaa tttctgcggt aagttcgtat
     1921 tttttctccg gtgttcatct tcttctcctt tcgattctac agtatataga tttattctac
     1981 atgacctata cacttgatag atacgttttt ttgatgaaaa acggtatgat tttatcaaag
     2041 aatcatttaa gtaagggaga gtggtgataa tcaaaaaaaa gttcacagtt ttactcacaa
     2101 tcatagtgac cggtatcatg agtggttttg ccttggttag tataaataaa caggtactct
     2161 atcggacaaa tgaatttttc catcaaacag atacttatac tccgattcga ttgccacaac
     2221 attttattgg gcaagaagaa tatgagcagc taatcatggt atttgaaaat gtctcatcag
     2281 aaactgagct ttcttatatg aaaaaaacag taaatgaatc caatgaagta gatacatctt
     2341 ggaacttcaa gatacagcca aagcttgaaa tgacattgta ttatcaaggg gatgtcaaat
     2401 cttctcacga gaaggtaccc tattctaata cctcctttcg cgtaacgtcc attgaagaat
     2461 cgatcaaaat aaaagatttt gaaggtgaat ttttcttgat gacgagagaa aaagaagcct
     2521 atgaacggtt catttcacta ttcactgatc gattcaatca agcatttcac actgattatg
     2581 ccactaatat ttttgaagac tttgaaaata gctattcgta ttcggttatt tcaaatacag
     2641 acgtatataa ttatcgagtg tatttaacta ttggattgat tcttttattc cttttgttat
     2701 catccttttt cttattgatg aataaagaaa tcagtttatt gttgaataat gacttttcat
     2761 tacatcaagt attgtggtgt ttattgggga aaaagaaaat cattattaca ttcataattg
     2821 caggaatcat tggtggtttt atttttatgt attataagga gcaatttctt tatttgttcc
     2881 agatgtacgt tttcttgttc agcggaatat atggtatctc tttgatttct cttttattag
     2941 ttgaaaaaat cgcttcgtta agagaagcgt tcaactatat ccaatacatt ctttttacat
     3001 ttggattgtt gttttctctt cttttgaccg ttgccaatgt cgaattagca actatcgttt
     3061 tttcttcttc acagttagct gtttcccatg aaccaccaaa agaaatcgct ggtgaggact
     3121 atcatgtatt ttatccagta accatcggga aaaaccacgt ggattttatt tattccaatc
     3181 gttttgcatc agcagcagat caggaattat atgaaacttt gaataaaaac ggaagtatat
     3241 tagtcaatgt atcagattac ttgaatgaag aaaatgaaca gtttggcaga gggataaaaa
     3301 taaatctgaa ttatcttaag aaatttcctt tgattgatgt ctctggaagg ttgatccaaa
     3361 taaccgaaaa agaaacgcac cctgttatat tgatccctga acgatataga catacagatt
     3421 taaaaaatga cctggcgcaa ataacagaat attatcaaga aatcagtgaa aaagaaccga
     3481 aatttctatt tataaaaaac aatcaaccca tttatacatt tattccttct atcccctgga
     3541 tcgaacatta tccggttgtt gaaatactga cattgaaaaa cagtatgtat ttggaaagaa
     3601 atattctcag cggagaaatc tatccaccgt taaagatcaa gataggctct ttgtcgaaag
     3661 aaaggttatt tgagctgatt gaagaaagtc agttacgtga taacttgcag ttatcatttc
     3721 cgtatactca gactgaagag atagctgtca aagtgttaag cagatcattt cattacttga
     3781 tacagatatt tttactcact ttcttttctt tcttcttgtt gagctatgtc atgttatgca
     3841 tatattttgt ctacaattgt cggaaaatcg ctatctttcg ttcaagtggt tattcgctct
     3901 ttgaaacgta taaagatttc ttcatgatga acctcatcaa atggggaacg acaagtgtaa
     3961 tcttcctttt tcttatagaa agagagccta aatatctttt taatattttt ttctttagct
     4021 tcattgattt tattctttca gttgttttta ttttgtctac agaaaagaaa agtcagttat
     4081 tgctgatgaa tggaggttaa caattggagc cgttgatagt gataaaaggt gcgaaaaaaa
     4141 tcattcgaaa caaaacgatt cttcatttgg atcgtttcac tgcggatgct ggggatcttg
     4201 tgactgttgt tggagaaagt ggagcaggta aaagtacgtt attgaatata ttaggattga
     4261 atgatcagtt cagttcagga caattctatt tgttcgatca agagacgaaa caattaactg
     4321 ggagagagaa gcgcttgata aaaagaaata ccatatcttt tctttttcaa gattttgggt
     4381 tgattgaata tgaaacaatc gattttaatt tagatattgg attgaagttt tcgaatttaa
     4441 atgtttcaga taagcgaaca gcaaagtatg aggcattgaa aaaagtaaat ataaacaaga
     4501 agctaagtac gcctatctac acattatctg gtggtgagaa gcaaagaatc gcctgtgcga
     4561 gagtcttatt gaagaatagc aaaatcattt tagccgatga accgactggg tcattggata
     4621 aaagaaataa ggataaagta gttgaaatct tatcgcaaca agcttcccaa ggtacgttag
     4681 ttatcgtagt cacgcatgat ccatatctga ccaaaatagg aaacaagaag atcatgcttt
     4741 aaaaatcaaa aaggaaagga tgtcgtttta tgaaaaaagc agttattatt tgtgcactag
     4801 ggataggttt tgttggagga aacgctatgt catctgaagt ggaagcaaat tcagttcacg
     4861 gtgaaatcta ttacaaatct ttaaagccag gagagattca ttttgatgct aaaggtaata
     4921 ttattaagtc aaatttacca gtagaccggg aaatttctag aacagcaatt aatcatagct
     4981 ctggaagatg ggtttattat agtgatacaa cttgtacgag aaaaacaggt cattctaacc
     5041 actatagtcg tgtctataat cgtcacggtg caaaagcgaa agttggaaac tctattcgat
     5101 cagcaaatgc aacaaaagga gtatgggcct atgcaagtgc gacaggaaat agaactgaca
     5161 cattctcatg ttggtacaat ccaaccggtt ggtattaagt atccaaaagt ttatataaaa
     5221 tagaaaaaac atataatgaa acag
//
LOCUS       DAZKCW010000111         5232 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000111 DAZKCW010000000
VERSION     DAZKCW010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.115"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            236..1111
                     /locus_tag="ACG84Z_002668"
     CDS             236..1111
                     /locus_tag="ACG84Z_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFP9163461.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            1215..1979
                     /locus_tag="ACG84Z_002669"
     CDS             1215..1979
                     /locus_tag="ACG84Z_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFP9163462.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            1966..3408
                     /locus_tag="ACG84Z_002670"
     CDS             1966..3408
                     /locus_tag="ACG84Z_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFP9163463.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            3419..4749
                     /locus_tag="ACG84Z_002671"
                     /pseudo
     CDS             3419..4749
                     /locus_tag="ACG84Z_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            4762..5220
                     /locus_tag="ACG84Z_002672"
     CDS             4762..5220
                     /locus_tag="ACG84Z_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFP9163464.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
BASE COUNT         1773 a          767 c         1099 g         1593 t
ORIGIN      
        1 tttcttatag agagttgcta tatttttttt gtttttatgt aattacctcc aaatcaattc
       61 gatacaagta ttatcataaa acgagtaaaa aagatattga taacgctttt attatgtgtt
      121 aaactatttt tgtaaattat gtagggtgct actattcaat taggcacgac ctaagaaagg
      181 gttctttctt aggtcgtttt ttgtctttaa aaattgtttg gagacaaaaa tatgtatgaa
      241 ggagtctgca agttgttttg ttttatcata tagtggaggt gaattaacgg tgtatgtgat
      301 gaaaaagctg aatcataatg ctgtattgat cgatgacgat ggaatagaaa aaattgcgat
      361 ggggaaaggg attggctttt ctgctaaagt gagtaagcca tttgatgttg aggatgctga
      421 caaattattt gtattagatt ctaaagaaaa gatcaaacga ttcagtgaga tagtctcgca
      481 gattccaatc gaatttatgg attttgcgga agaagtgatt gaactgataa cagctaggat
      541 ctcctctcca ttagattcaa atatctatat tacattgaca gatcatattt attttgctat
      601 tcaacgaaaa agagaagata gagatgtcac agcaattatg ttgccagaaa tgagattcct
      661 ttatccaaat gaatatgata tagcaataga agtggtcgag cgaatcaatc atcgatatca
      721 aaccgagtta gggtcaaatg aagtaggatt catcactatg catatcatta atgctgagct
      781 aggagagcct aatagtttaa agagcttaaa aatagtagaa atgacgacca cgattttgtc
      841 ccatctagaa aaatcctatt caaacgttta tgataaagaa tcactgactt atcatcgctt
      901 aatggttcat atcaaattcc tggttaaacg cttgatttat caggaagaaa cgccagtaga
      961 aaatattggt ttttttactg aaacatttaa acatagcaaa gcgtattgta cagcactaaa
     1021 gattaaagat atcatcgaac agcaatttca acttgccatt caagaaaatg aaatcatcta
     1081 tttggcaatt catctagcac gaatctatta aaataagggc gtaactatct ataggcgcaa
     1141 ccaaatgaca catagtaaat ggactatgat tatttggttg cgcctatttt agtagaaaaa
     1201 agaaggagaa tgaaatggga aaagtgattt ttaattcgga tgattttggc tatagccatg
     1261 gtgtgaatta tgggattatg gatgcttatc agcgaggaat tttgacatca actacattga
     1321 tggcaaatat gccgggtttc gagcacgctg tgaaactaag aaaggaaatg cctaggctag
     1381 gtgtaggagt ccatttaaca ttgacgtgtg gcaaaccact tctcaaaact gtcgatactc
     1441 ttatcgaaag cggagagttc agatccttat cttattatca gcatccattt aacattgaca
     1501 aagatcaact gtatcaggaa tggaatgctc agattcaaaa aatttatcat gcggggatca
     1561 taccaactca tttagacagt catcatcata ctcatacttt ggatgaaaac caggaggtag
     1621 ttgttacatt agcaaaaaaa tatgatttgc cggttcggag caactttgaa cgaaaagatg
     1681 aagttcgtca tgtcgattat tttgagcctt gtttcgatgt cgtaggagaa actgatgaaa
     1741 aaaaacgaca aatcaatacg agtgtggaag aatatttggc aagtttactc atgatattga
     1801 gagaagataa aacgatcgaa gtcatgtgtc acgcagcgta tttggatcag gaattgttaa
     1861 atggttcaag ttttgtgtat cctcgtactc accaagtcga atttttaatt cattcagcat
     1921 ttgctcaaaa agtgaaaaat gatcctttga ttgagttagt aacatatgag gatatttaat
     1981 agaggaggaa taaaaatgaa tgttaaatca aatgtgcaga agcttggaag agcgatgcta
     2041 cttccagttg cagcgatgcc attagcggga ttgatcatgc gtttatcagc tgatgatatg
     2101 ctgaacatcc cagtaattgg tgcagctgga aatgccgttt ttggaaactt ggatatctta
     2161 tttgctatag gagttgcaat cggttttgtc aaaaataagg acaaaggaat acctgcactt
     2221 actggttttt tagcgattgc taccttgaaa aaaggcttag aaatcatgga cccagaagtg
     2281 aatatgggga tttttggtgg aattatttcc ggtttagtag cggcatggac gtataatcgc
     2341 tttaaagaac aaaaattacc agtagttttt tcttattttg cgggcgaaaa attcccattg
     2401 actatggtga tgattctaca aacaatcgca gctatttttt tgggctttat ctggccgctc
     2461 atccaaattg ggattgataa ttttgcaaaa ctgctcgttg atatgggggc attaggtgtg
     2521 gggatattta tgtttttgaa tcgtttgctg atcccctttg gactgcacca tgtgttgaat
     2581 acgtatattt attacgattt aggaagctat acatctccta gcaaggaagt tttcagagga
     2641 gagatgacac gctttatcaa cggagatcct caggctggac tgtttttatc aggttttttt
     2701 gtagtaatga tgtttggtat accagctata tgtctagcta tctataaagc agcttataaa
     2761 gaaaataaag agatggtcaa aggaatcatg ggaagcggtg caggaacttc atttattgca
     2821 aatatcactg agcctgttga atttagtttc atgtttcttt ctcctatgtt gtacgtgatc
     2881 catgcacttt ttgccggttt agcagggatt gtctgttact tattcaatat acgaattggt
     2941 tttacattcg gagcatgtat tgttgattat ctcatcaatt ttcgaatcgc taccaatgct
     3001 attttgattc ttccaatcgg aattttcttt tttgccttgt attacgttac tttttattat
     3061 ttgatcaata agagaaacat tcagacatta ggacgtgaag ctaaggcaga gtttggcaat
     3121 gaagtaacct tagaagaaac agagttaggg ttagcaagta aaaattatga atatatggca
     3181 acaaaaatgc tacaagcgtt tggaggaaaa gccaatatcc tggatgtcta tagttgtaat
     3241 acacgcctac gggtagaggt agtggatccc accatggtcg aggaacagcg aatcaagcaa
     3301 ttagggataa gcgggatcat taaaccaact gaaaaaaatt atcaaattat catcggctta
     3361 gaagtgactt atgttatggc agaattcaat aaattattag aagaatagaa aggaaaagat
     3421 gatgatgaaa aaacagatta tcactatagc tggaggcggg agtacgtata caccaggaat
     3481 cgttcaagcc attttgaaca atgaaaaacg gttgccatta tctgaaatac gtttatatga
     3541 tattgatgaa gaaagaaata tggatatgta cttgattgtt aaatttatgc tgaaaaaaaa
     3601 ggtttttcaa atattcgcat tcgtgcaacg gatgatccaa agcttgcttt tacaggatgc
     3661 gattttgttt tctcacaaat tcgtgttgga ggattggaga tgcgagaaaa ggacgaaaag
     3721 attccactta aacatggatt agtaggacag gaaacgtgtg gactcggagg atttgcttat
     3781 gggatgcgct caatcaaagg tttattggaa attgtcgatc atatacaaga ctatgccccc
     3841 aaagcatgga ttttgaatta tacaaatcca gagtcgatcg tttctgaagc tgttcgtcgt
     3901 aaatatccga atgtaaaaat gattaatgcc tgtgatatga ctatttcaat tgaagaaacg
     3961 attgcagtga attacggtta tgatcgtaag aattggatcg ttacgtatta tggtttaaac
     4021 cactttggct ggtatacatc gatttatgat aaagaattgc aacgagaaat tatgccagag
     4081 attattgaaa aactaataac aaaagaaatg caagtcgccg attttaatat aggagacaaa
     4141 acttggcaaa aaacctttca aatgatgtca gtcatcacga aaaattttcc aagtaatatc
     4201 ccgaataatt acttagagta ttacttatat cctgatatgg tcgttgagca tactgacaaa
     4261 gagtatacac gtgctaatat ggtcatggat ggacgagaga aaaataccaa agaaatggct
     4321 gataaaatac gccgcggtat tgtggaagaa gtattgaact ttaattttgg ggagcatgga
     4381 caatatatcg tcgatatagc tatttccttg ttgaatgatg atcgtcgtcg ctttatgcta
     4441 atcgttccta atcaaggggc gattccgaat ctacggtcag atgcagttgt tgaaataccg
     4501 gcatatgttg gtgcaactgg tgtggagaca attacactaa gaaaaccaat cagtgatttt
     4561 cataaaggat tgatggaggc acaagttgca gcagagaagt tactagtaga tgcttacttt
     4621 gaaggttctt atcaaaaagc tttacaagca tttacattga atcaaaccgt accaaatgcc
     4681 agagtcgcaa aaaaaatact agatgaaatg atcaaagtaa acaaaaaata ttggccagca
     4741 ttaaagtaga ggtgataaaa agtgcatttc tttaaaacaa gaaacattct aaaagctgta
     4801 gctagtggtc aaattattcc attaacagca gtaaaagacg aggtcttttc ttcaaaaatg
     4861 ataggagttg gatacgctat aacgaatcat gatggatata tccatgcgcc agttaaagga
     4921 ataatcgata atatatttcc tacccgacat gccataacga tcgaaagtga atctggcaga
     4981 aaaatactga tccatatggg tttagataca gttgaactcg aaggaagtcc gtttcagata
     5041 cgggttgaaa gtaaccagga ggtaaaagaa gggacactgt tagctattat agatttgaag
     5101 aagttggagc aagcacaaaa agatacggtg atcattgtag tttctccagg catttttgaa
     5161 ggaaatttat taaaacaaaa ccaagaagta aagattaaag atagttgttt tgaattttag
     5221 tgtacgatga aa
//
LOCUS       DAZKCW010000112         5190 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000112 DAZKCW010000000
VERSION     DAZKCW010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.116"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            107..1153
                     /locus_tag="ACG84Z_002673"
     CDS             107..1153
                     /locus_tag="ACG84Z_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9163465.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKM
                     YKTAYNMLWRIYNR"
     gene            1167..2246
                     /locus_tag="ACG84Z_002674"
     CDS             1167..2246
                     /locus_tag="ACG84Z_002674"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9163466.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            2265..3689
                     /gene="wzy"
                     /locus_tag="ACG84Z_002675"
     CDS             2265..3689
                     /gene="wzy"
                     /locus_tag="ACG84Z_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HFP9163467.1"
                     /translation="MKEKINILMFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAIC
                     TWHWRKGDSIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSES
                     DMIMVKWYSCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIV
                     VPIVFVSKLLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKV
                     ITRFVFIIFALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIG
                     IYILNVITKARDGGGLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNG
                     IYPFANTYLTSLLGSISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNG
                     GYIGGIVYIFIIGIVIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIV
                     KNFVYGVLIILLINFFLQQFNKRL"
     gene            3735..>5190
                     /locus_tag="ACG84Z_002676"
     CDS             3735..>5190
                     /locus_tag="ACG84Z_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFP9163468.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWARKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIILVNVLFYRR"
BASE COUNT         1843 a          608 c          941 g         1798 t
ORIGIN      
        1 gcaaatataa agataattgg aaaggaatta gtgctaagtt tgcattgaaa aacaaatggg
       61 tatttttaat ttatatttat aacaaattga taaagaggta ataataatgt cagttaagat
      121 tagtgtaatt gtaccttgtt ataatgttga aaaatatatt gatgagtgta taaatagttt
      181 gataaatcaa acattgaaag atattgagat tattttgtta aacgatggtt caacagataa
      241 tacgttggcg atattaaaga aatatgaaaa gcttgattct agaataaaag tttacgaaca
      301 taaaaatatg gggttagggc caactagaaa tcgagggatt aaaatagcta atggagaatt
      361 tttggctttt gtggattctg atgattttgt ttccaatact atgtttgaaa gtttatataa
      421 ttgtgcaatt gcagagaatg cggacattgc aattggagaa gtaggcattt tttctgatag
      481 agaaatagaa agagtaaaaa taagaaaaag tctaacgaac ttaaaaacaa ttgaattagc
      541 aacatataat aagaaagaat tttttaagca attctatttc aatcgtttat attcacataa
      601 tgcttgggat aagatatata gacgtagttt agtattagag tttaatttat catttggtga
      661 taacaaaata atttttgcag aagataattg gtttcaatta caagtattta tgacaaatac
      721 aagaatctgt ttcgtagata aattgtgtta ttattatcgc caacaaaata attctataat
      781 gcataagcca aaaagtaatt tggtttttag acatggaaat atgattgctg attatgaaaa
      841 gttgataagg caaaatggaa acaacataat agataaaaaa gcttgtatgt tggttgcatt
      901 tgatgtacta attatggaga tttttaatca aaaaaacgtt ggtggaacat gtgaagatta
      961 taagaatgca ttagtttctt tgaaacatca taaaatattg agagaaaata tttcaaatat
     1021 agttagaatg aaagcatatg aacttgaacc taatatgaga aagaagttag cccttgtgac
     1081 cattagtata atgtttaatt ttaaaatgta taaaacagcg tataatatgc tctggagaat
     1141 atataatcga taaagaggta ggaaatatga ggaaattgac ctttgtgata ggaattatgg
     1201 gaaaaggagg ggcagaacga gtaattgcga atttggcaaa taattttatt caagataact
     1261 gggaaattga tattataact atatatggga atcggcaaga ctatgaactg aatagaaaaa
     1321 tacaggtaca tccaataata tgtaaaagtt cgtttcgtgc atttagacct ttggaacgct
     1381 ttaaggaact taggaaaaaa ataagggaaa tacagcctga tctggttatt tcgttccttg
     1441 ctgatgtaaa tatccatgtc attatttcat tgttaggagt aaaacaaaaa ttaattgttt
     1501 ctgaacgaaa tgatccacaa cggaatccag aagaaccatg gattaggaaa attagagatt
     1561 ttctttataa aaatgtagat ggaattgttt ttcaaacacc agacgcaaaa aaatatttta
     1621 gtaagatcaa tgataaaaaa gtaaaaacaa ttataattcc caacccaata aaggaaaatt
     1681 taccttatta taataaaact acaagtagta aaaaatttat tactgcatgt agattggata
     1741 aacaaaaaaa tttgccctta atgattgatg caataggaaa acttattcat gaaggatatg
     1801 agtgtgaact ggatatttat ggagaagggg gattaaaaac cgagcttgaa agttatatca
     1861 accataatgg attaacagaa tttgttcatc taaaagaatt tacaaataaa atacatgaaa
     1921 agatgcaaaa tgcggcagga tttgtaattt cttctgatta tgaaggtata tctaattcta
     1981 tgttagaagc actggctatt ggagtgccag ttatcgctac agattgtcca gtaggtggcg
     2041 caagaatgta tttaggtgat agaaatgaaa taggtcatct tgttgaatgt aataatctag
     2101 ataagttaac agatgcaatg cgtagggtac ttttggatag agaaagtgtg gtaagaaaag
     2161 cgcaaaaagg aattaaacta agaaaagaac tgacatctaa aaatatttca aatatatggt
     2221 acgaatattt aaaccagttc ttttaaccaa aaggaggata ttgtgtgaaa gaaaaaataa
     2281 atatattgat gttttcgtta acgttagtcg cgtttacaat attttgcgct ttttcattaa
     2341 atcagaacta ttggctaaat tggcttggaa tattgattta cttatatgca atctgtacat
     2401 ggcattggag aaaaggagat tcaatatttt cattatacac gatttttttc actctttttt
     2461 tattatttag ttatgggcaa tgcattatgt gggcattcgg tattggaaca gatcgtggaa
     2521 tcggtacaac agtagtagct tatggtacgg ggattattcc tagtgaatca gatatgataa
     2581 tggtaaaatg gtattcttgt atttctatgt ttgtatttca cataggagca ctcttattta
     2641 cgagaaaaac cacactaaga aaagttagtt ggtatgaatc tggagatgct gatgccgata
     2701 gaaagttttt atttaaaata gggtgtatca tttctataat agtagtaccg atagtttttg
     2761 tttctaaatt actagaggta cgtatagcat tagtccatgg ttataatgca ttatattatg
     2821 gtgattatgc tacacaaagt ggatatttac aaattattct atatcttttt tttccagcct
     2881 taatatgttt attaattggt agcaactttt caaaagtaat aacgagattt gtttttatta
     2941 tttttgcttt atattcttta ttaggaatta tgtcaggaga cagaggaagt tggttgtata
     3001 gctctattat actcatatgg gcatacactc aatataaagg aacctttaat tataaaaaat
     3061 taataaagtg gcttatttta gctgttatag gaatatatat tctaaacgta ataacgaaag
     3121 cacgtgatgg tggaggacta agtaaactta ctttaaaaga ttttacatct gtatttgatt
     3181 cagatgattc tcctttagtt gattcttttt ttgaaatggg ggggactatg agtattataa
     3241 cttttttcct aataagtggt aatggaatat atccctttgc taatacttat ttgacctcac
     3301 tcttaggctc tatatcaaca agaatgctat caatgtttgg aataaagttt gttttattag
     3361 ctgattggtt ttctcaggat tatttaggaa tcacttgggg gactggattc tcaatgattg
     3421 cagaagccta tgtcaatggt ggatacattg ggggtatagt ctatattttt attattggta
     3481 tagtcatcgg taaaatcctt tctaatagta tagacaacca agatattgaa aatcatccta
     3541 tgaagatgtt tttggctata actacagcaa atattataat gggttttcct agagctgctt
     3601 catatttaat tgtgaaaaat tttgtgtatg gtgttttaat tatattgttg ataaactttt
     3661 tcctacagca atttaataaa cgtctttaat atttaagctt aataaaaaga taaaacaagt
     3721 caggagttgc aaaaatggaa agaactgctc ggctcaaaaa aaacactatt tgggctctgg
     3781 tgtttcaaat aacttctatt gtctgtggta tgatcttgct acgtttgata ttaacaaagt
     3841 acggatccga ggttaatgga atgattagct ctattaacca atttctacaa attatttctt
     3901 ttttacaatt aggagtaggc gctgtaatgc aatcaactct atacaaacca ctagcagaaa
     3961 aggataattt aatgataagt caaatcttag cttctggagg gaagttttat cggcaaattg
     4021 catatattct actagtatac gtgggtttgt tacttgcagt ctattatgtt ctcgttccta
     4081 atgaatttgg gagatcatat acaatggcaa tgattgcaac attaagtatt aattcatttg
     4141 ctcaatatta ttttggtatt gttaatactt tgttattaag tgctgaccag aaaatttata
     4201 ttacgtatat tgcacagaca atagcattta tttctaatac agttgcatgt gctttattaa
     4261 ttagtctgaa cacagagatc cttatggtaa aacttattac tgctataatt tatcttgctt
     4321 gtccaatata ttatagatgg tatgtggatc gaaactataa tataaagagg aatgtgtcat
     4381 atgataagga accgatccct caaaaatgga atggggttgc acaacacgta gcttctgttg
     4441 tactagatag tactgatgtt gtagtgttat ctatattttc taacctgata tatgtatcta
     4501 tatataatgt gtacaattta gtaatatacg gagtaaaaca gctattcatg gctatgacaa
     4561 atggcgttca ggccttacta ggggaacttt gggccagaaa agaaatagaa gttctttaca
     4621 aaacatttgc atggttcgaa tggattgtac atactttgac agtttttatt tttggctgta
     4681 ccggtatact aatcgttcca tttattcaag tatatacaag aggagtaaca gatgctaatt
     4741 ataatcaatt atcattcgca gctttacttg taactgctaa cgcacttcac tgtctgcgta
     4801 caccttatca tgtaatgata aaagcagctg gtaaatataa agaaactcaa aatagtttta
     4861 taattgcttc tttgttaaat ttaggtttat cattaatttt ggttaaacca ctagggctag
     4921 ttggagtagc attaggatct ctaatttcaa tcacatatca tacactttgg agtgcaaatt
     4981 ataattcaaa atatttgctt aaatggccga tgaaaaaatt ctataaacag ttatttgtaa
     5041 acatcttaac tgtagttctt tcttttgggg cgacatcaca attgaaaatg atgtcaatca
     5101 catatttgga ttggattgtt ctcgcaatta aatgtgcagt tattgtattt atatgtataa
     5161 tcctagttaa tgttttattt tatagaagat
//
LOCUS       DAZKCW010000113         5106 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000113 DAZKCW010000000
VERSION     DAZKCW010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.118"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(435..977)
                     /locus_tag="ACG84Z_002677"
     CDS             complement(435..977)
                     /locus_tag="ACG84Z_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HFP9163469.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
     gene            complement(1290..1841)
                     /locus_tag="ACG84Z_002678"
     CDS             complement(1290..1841)
                     /locus_tag="ACG84Z_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9163470.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            2158..2556
                     /gene="merR"
                     /locus_tag="ACG84Z_002679"
     CDS             2158..2556
                     /gene="merR"
                     /locus_tag="ACG84Z_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFP9163471.1"
                     /translation="MAYFISSFSEKCGVNKESIRYYERKNLLPEPDRTNSGYRVYSEE
                     DVKRVKFIKHLQEIGFSLNEIYKLLGVVDKDNIRCEGMFEFVSKKEREIQKKIENLNR
                     IEYMLKDLRARCPDEKELYACPIIEVLIEN"
     gene            2570..4210
                     /gene="merA"
                     /locus_tag="ACG84Z_002680"
     CDS             2570..4210
                     /gene="merA"
                     /locus_tag="ACG84Z_002680"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFP9163472.1"
                     /translation="MNQFRMRIQGMTCTGCEKHIEKALESMGALNAKADFSQSEAVFQ
                     LPDDYAIENAIEAVKKINYQPEEVEKLPVQKRVMTNNKEDYDLLIIGSGGAAFSAAIK
                     AVEYGSKVGMIERGTVGGTCVNIGCIPSKTLLRAGEINQSAHVNIFEGLHTSTGEVEL
                     DRLVDQKNELVDDLRKQKYTNLIDDYGFDLIKGEAKFIDENTVTVSGQTYSAQRFLIA
                     TGASPLLPRITGLKEVDYLTSTTLLELRKVPKRLTIIGSGYIGRELGQLFHNLGSEVT
                     LIQRSKRLLKEYDPEISEAMEKALIEQGIKLISGATYERVEQDGNIKKVHIIVNGKNK
                     VIESDELLVGTGRKPNTEVLNLSAAGVQVGPNNEIKINAFAQTSNRKIYAAGDVTLGP
                     QFVYVAAYEGGIAAGNAIGGLNKAIDLSVVPGVSFTSPQFATVGLTQQQAKEKGYEVK
                     KAVLSLENVPRAIVNHNTTGVFKLVVDRKTQKILGVHIVSENAGEVIYGASLAVKFGL
                     TVADLKDTLAPYLTMSEGLKLAALAFDKDISKLSCCAG"
     gene            complement(4735..>5106)
                     /locus_tag="ACG84Z_002681"
     CDS             complement(4735..>5106)
                     /locus_tag="ACG84Z_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFP9163473.1"
                     /translation="SLNLTPFTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFA
                     FVLVLSLTFEIIQFIFAIGATDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIF
                     VGILLLVLLLVYRTHLRINYV"
BASE COUNT         1709 a          874 c          969 g         1554 t
ORIGIN      
        1 cttaagatta atgacactaa attaacagac tatacgtagt atctatttgc tatgaccata
       61 tcttatatcc ataagtcaac tcagccggac taaaagggct aatcttacta gaacacaagc
      121 tgcacttgat atgcaaatta accctgaatc ggaaaggtgc ttaaattgga tattaacgga
      181 gggataaagt aaaatttatc tctagggaat gtttagaaag gatccaagtt ccttaacaag
      241 tgacaattag taatgtagta acaacgatag attgtatgcc gaacatttca atttgatacg
      301 tataaaagac gatttcaagc tcatccgtga taaataaccc acatgaatga tttgaaatcg
      361 tcttaaaatg ctttatttta taacccaaaa tagaataatt acttcaaaat gacgtcgcat
      421 atcactatta atgattaatc gatgacttcc ataatcattt taagttcccc ggatgttaaa
      481 tcctcgctaa aaatgccagt aactttttgt ccaggtccaa tttcctttga tgataggttt
      541 aacaaagaga tagggatata gattaatccg ttttgtttca aagacagagc caatattttt
      601 ttccttgttc gaatagctgc atcatagcga agagaagagt aaacacctct gccaacaata
      661 gaaatatgct tccccaataa taaatcaagg ctacctatta cttgtaattt ctgaaaggtc
      721 gtcccatccg ttttgatttg aatatcctgt aaatttattt tcctgtctaa ggcatcttga
      781 aaaaacaagt gtgtgcctct gcgataatca atgccacaga ggtgcataaa attagttgtc
      841 gaaaaaataa tcgctaccgt tgagacttct ccgacaaagg atactttttt atctacaaaa
      901 tgttcttgta agagatgagc agccttataa atcgcgttta actgtctggt aatttgggtt
      961 gtctctttta tagacatgcg tttgtattct ttttttgccg cgtgcgaaga atgctccttt
     1021 ttcccaataa aaaaagctgc tcaaaagagc agccttttgt acaggtttag ttttggtgct
     1081 tgccacccgc cggaccctta cgttccggat ttgtatcgag tttagttttg gtgctcgcca
     1141 cccgccggac ccttatgttc cggatttata tcaagttgac tatgagcctg ctctcatttg
     1201 tatatataat ataccaaaaa aaggttgatt tgtccaatac tgtgggtgat tataaccgtc
     1261 ttactgtgct tatctattat ataatacaat caaaaaccta accgaaaatt taataacgtt
     1321 tcactgattt catcttcatt aattccgatg tagcgtttgg taatcttctc gctgctgtga
     1381 ccaaagattt ccattaaggt ggccacgtct ttggttttct tgtaatagtg gtaaccaaag
     1441 gtttttcgta gggtgtgggt gccgatatcg tcccttccta acagcttcgc gaccttttga
     1501 aacatctggt agaccgtatt gacttctaaa tggccgccct tagtactggg aaacaagtaa
     1561 gcctccggat ctaagggtgc ggtatagccg tgaatcaagt cctgtaagct gcttaagtat
     1621 aaaatgcgtg tttttcctgt cttttgctcc acgatgcgcg ggttttttga ggtaatcacg
     1681 tcttttttct tgagtttaac gatgtcggac atgcgcagac cgctgttaat tccaattaga
     1741 aacaagaaaa cgtcacgttc cgcattttta ttccgtcgca ggcaaaataa aaaatcatta
     1801 atctcctgtt gcgaccgtag tggctgaaca ttatagccca tgacaatccc tcctttttag
     1861 tctgttcgaa tacatgatta tagttattac aacacgaaat cgtgtgttta gggggagtaa
     1921 aaaaaaagaa ccctataagg ataggattct tgatacatga ttttatgtaa tttcatgtat
     1981 ttaggtccga tattatttat tataaaagaa gtctcaaaat ttattggtac cacatttaat
     2041 tttcacttca tttttgaaag taaataagaa ggaaaatgat attcccccct tcgtattatt
     2101 tttggttgga catgtaccta agtacatggt ttataattaa aaaaaggatg tgatagcatg
     2161 gcttatttta ttagctcctt ctctgaaaaa tgtggtgtaa ataaggaatc cattcgatat
     2221 tacgaacgaa aaaacttact accagaaccc gatcggacta attccggtta tcgagtttat
     2281 tcagaggaag atgtaaaacg agtaaaattc attaaacacc tacaagaaat tggcttttct
     2341 ttaaatgaaa tttataaatt acttggtgtt gtagataaag acaacattcg ttgtgaaggt
     2401 atgtttgaat ttgtctctaa gaaagaaaga gaaattcaaa aaaaaatcga gaatttgaat
     2461 agaatagaat atatgctaaa agatttacga gcaagatgtc cagatgaaaa agaactatac
     2521 gcgtgtccta tcatagaagt attaatagaa aattaacggg ggtaggaaaa tgaatcaatt
     2581 tagaatgcgc attcaaggaa tgacctgtac tggctgtgaa aaacatatag aaaaagcgct
     2641 tgagagcatg ggagctctca acgctaaagc agatttcagt caaagcgaag cggtatttca
     2701 attaccagac gactatgcaa tagaaaacgc gatagaagca gttaaaaaaa taaattatca
     2761 gcccgaagaa gtagaaaagt tacctgttca aaaacgcgtg atgactaata acaaggaaga
     2821 ttatgatttg ctcattatcg gttctggtgg agcagctttt tcagcagcta taaaagcagt
     2881 cgagtatgga tcaaaggtgg gcatgattga acgcggaact gtaggcggaa cctgtgtgaa
     2941 cattggttgt atcccttcaa aaacgctgct tcgagctgga gaaatcaatc aatcagcaca
     3001 tgtaaatatt tttgaaggat tgcacacttc tacgggagaa gtagaattag accgcttagt
     3061 cgatcaaaaa aatgaactag ttgatgattt acgcaaacaa aaatacacta atttaattga
     3121 cgactatggt tttgatttaa ttaaaggaga agcaaaattc attgacgaaa acactgtgac
     3181 agttagtggg caaacatatt ctgcccaacg gtttttaatc gcaacgggtg cttctccact
     3241 cttacctcgt attactggac ttaaagaagt agattattta actagcacaa ccctccttga
     3301 actaagaaaa gtaccaaaac gattaacaat tattggatcg ggttatattg gaagagaact
     3361 gggacagctc ttccacaatc tgggttctga ggttaccctt attcaaagaa gcaaacgact
     3421 tttaaaagag tatgatccag agatttctga agcaatggag aaagctttaa tcgaacaagg
     3481 aataaagctc atttccggag caacttatga acgagtagag caagacggaa atattaaaaa
     3541 agttcatatt attgtaaacg gcaaaaataa ggtcattgag tcagacgagc tactagttgg
     3601 aacaggaaga aaaccgaata cagaagtatt gaacttgagc gcagcaggcg ttcaagttgg
     3661 gccaaacaat gaaatcaaga taaatgcttt tgctcagaca agtaatagaa aaatttatgc
     3721 agcaggagac gtgacattag gacctcagtt tgtctatgta gcagcctatg aaggaggaat
     3781 tgcagcagga aatgcaattg gtgggttaaa taaagcaatc gatttatcgg tagttcctgg
     3841 agtatcattt accagtccgc aatttgcaac tgttgggtta acacaacaac aagcgaaaga
     3901 aaaaggatac gaagtaaaaa aagcggtatt gtcattagaa aatgttccta gagcgattgt
     3961 caatcataat acgacagggg tgtttaaact tgtggttgat agaaaaacac agaagatttt
     4021 gggagttcat atcgtttctg aaaatgcagg agaagttatt tatggagcat ccttagccgt
     4081 taaatttgga ttgaccgtag ctgatttaaa agatacttta gcgccttatc taacaatgtc
     4141 agaaggctta aagttagcag ctctagcctt tgataaagat atttcgaaat tatcttgttg
     4201 tgcaggttaa tatttctatt tagtttcttg tagtagctgg taacaccttg gtttatcttt
     4261 cgttattatc tataacgata ggagttgaag attatgacat cagcaaacgt ctacgtgcca
     4321 attaatagct ctattctagt ggaggttgaa gaaataaaag actatttaga aacgcaattg
     4381 ctcatttagg caacgcagca agatattatt gaagatgcga ttgttgcctt acgtgcttaa
     4441 tatagataat taaatcgtat caaaaaagga ttctaccgct taaaggggta ccgtcaggaa
     4501 aatgcggatt tacaacgtta aggaaattta ttaaagagac caattcctca gcactaaaat
     4561 tgataattgg gctttctttg ttactatagt gttaggtaag ctttttactt tatcaccggt
     4621 tttcccctca cttcacacct acgggcgagt ttccccacat cccgttttcc atctaatcca
     4681 attcattcaa tatctttatg tgtatgaaag atcagattgc ttgatttaga catcttacac
     4741 gtaatttatt cttaaatggg tacggtaaac gagcaataat acgagcaaaa gtatacctac
     4801 aaaaataata actctgtcta attttttttg attcatatgc ttattgctta aaccatataa
     4861 tttcagtcca agaaagcctc caacagtatt tgtaattaca tctgttatgt ctgtcgctcc
     4921 aatagcgaag ataaattgaa ttatttcaaa agtaagactt aaaaccagta caaaagcaaa
     4981 cttaggtaaa aatccgattt ctttaaaatt gacattcaaa agcaagccaa atggaataaa
     5041 gattataaca ttatctatca tctctctgaa attcccagta gcagtaaatg gagtcaagtt
     5101 aagact
//
LOCUS       DAZKCW010000114         4811 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000114 DAZKCW010000000
VERSION     DAZKCW010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.120"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(92..1177)
                     /gene="xerS"
                     /locus_tag="ACG84Z_002682"
     CDS             complement(92..1177)
                     /gene="xerS"
                     /locus_tag="ACG84Z_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFP9163474.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            1526..1721
                     /locus_tag="ACG84Z_002683"
                     /pseudo
     CDS             1526..1721
                     /locus_tag="ACG84Z_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
     gene            complement(3253..3771)
                     /locus_tag="ACG84Z_002684"
     CDS             complement(3253..3771)
                     /locus_tag="ACG84Z_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HFP9163475.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            4138..4386
                     /locus_tag="ACG84Z_002685"
     CDS             4138..4386
                     /locus_tag="ACG84Z_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163476.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
BASE COUNT         1580 a          786 c          732 g         1713 t
ORIGIN      
        1 atataaaaat gataatgaag cttgccttta aagttgggct tttatctaat tttagagaca
       61 ggcttcatta ttatactatt ttttactaca tttacaaagc gttcaaagca tcaattgtag
      121 ctgcattgtc tatatgagta tataaagttg ttgtatttgt acttgtatgt cccaattgtt
      181 gggcagttaa taccaatgaa tttgtctgtt gatagagtct agtagccaaa gtatgacgta
      241 atttatgtgg actgacttgg actctgaatc cttttgaata ttttgctacc atccgttcga
      301 ttgcaatacc ggatatacgc ttggcttctc cttgataaat tgctagaaat aaagcttttt
      361 cgttttctgt tactttgtat cgttctttcc gaatagctag ataattagct aaatattcca
      421 ttgcaaatgc tgctatattt actgcgtctc tcttatttcc ttttctagtt actaccacat
      481 tattcttttc taaagatagg tcctctaaat taatatttac aacctcggag agtcttaatc
      541 cagatcctaa aatcaatgca ttgatcgcca ggtctctttc tacatctcgt tgataataga
      601 tcaaagctcg tttgctcaaa gtttttttat attcattggc aatataatct agataatttt
      661 gtgtatcttc gtctagaaat aattttttct cgattgcgtt tgcacgggca gctaacgtag
      721 ttttatctgt gatagttgct acttgatcca taggattatt ttctaagtat ggttttccta
      781 aaggattatt ggaacttttc gaaagatatt taaatagaac ctttaatgct gtgatatttc
      841 tattgatagt agaagtagat agacctaagt tattattatc tttgagctta gtttttgttg
      901 tctctttttt tacattttcc tttgtgcgac gtttcaaatg agatttgtac aagtttagat
      961 cataggcagt taactgtctt atcgaggtga ttgaagtatc gggaacgata gactcactca
     1021 gaagccattc ataaaagagc ttataatttt ttagatattc taaagtagtt cgaggtgatt
     1081 gatctttatc ctcacgatct tgaacaaaat cttttatata atcgggcata tgaagtatga
     1141 ttgtatctat tttttgatat atttctgtat ttttcatgtt attcatcctt tcgataagta
     1201 ggggagagga gtatctctat aattggacta taccaattat agagtgtttt gtcaattggt
     1261 atactctgaa atttattaat ttatttcaaa aaagcagata aataggtata gatttaataa
     1321 tttaaaataa atggtataca tgaataggaa aggaaacaga aggaggcaat cttaattttt
     1381 taaattgtct aaattatata gaaagaacaa tctttctata taattagaca taagagggac
     1441 tacggttgat ttgatattaa caagcgtata tgaatgtata tacaaataaa aaaggggagg
     1501 gagaagttaa agaaaattca gagaagtggg gcactcagta gtattaacaa tttaaaagga
     1561 atttcttaaa gaaaatgggt tgcatcctgg agatacaatt tttttagata aagaaaaaat
     1621 tcaagcaaca attcaaaaaa atcttaactg ctgagattga tgtagcaata tctcaatcat
     1681 caacaaagta cgatcctgcc tttcaaaagc ttattgataa atgtttattc attataaaaa
     1741 taaaagaaaa atttatgtca gcttttttca tcaaagtggt aatgataatt cgtctattaa
     1801 ttgtattttt taggaaatat ggtataattg ttttaacgaa aaggtaattc atgatacacc
     1861 aaaaaccact agctggcggg ctagtggttt tcttttacgt tctattcaga ttaacgggta
     1921 ggcttactgt cttttttggc aataattttg caatcaagcc atttacagat gtaatgcgcg
     1981 gatacttctg ctaagattgc aaaaaacata tcgaaaaggt aattcataat acaacctcct
     2041 ccccttgcca taataggccg gggtagcaga cagcataaat attataccat aactgaaaat
     2101 ttcattttag tacatttcaa tatattgatg aaccagcaca ataaaacatg ccatgactaa
     2161 cagaaaaaaa cttattaaac cagatataac ttgtaaacat ccaactatat agaaaacgta
     2221 aattttctat atagttggat taagataacg actatttatt ttatcatatt tttactatac
     2281 cctatacttt tacttggtat atttatgaat aatcgcaaat ttacccctat actactagtt
     2341 tgtaagttag attaataaaa atactaaagt tatttgttct tttattaaat acacctacaa
     2401 cttataaatt gatggtattt agataacacg aaagaataaa aataacagct gatagtaaag
     2461 tttgttgacg attgctactc aatcgaaagt gagttagtgc gtatgaactt gcttctgaaa
     2521 acttatgaaa tgaaagacct tttacatctt gcagaaatcg gtactgggat taaactaagc
     2581 aataaaaact aatgttcccc tcattctttg aacttctact atttgattta tttattctga
     2641 taaatgacga tttcaccttc aggatcttca aatcccgtat agaatttatt taagatctct
     2701 tcagtatcag taataggata ggcgataggc cacataccct ttgatggtta gaataaactg
     2761 ctcaaaatct gtatcgtatg ttggctttag catattaaca aaggctatct ccaaattata
     2821 aaccataagc gttgaatcgt tcttaacaat ttcaattctt cctaacccaa agtcagaaga
     2881 tataattacc ggacttgcct tacccttcat gtgggttgtt gagattccat atttaaaggg
     2941 aattgtcggt actatcggcg gtctgaaaaa catcccaaaa ataaaaaaat ctttcccctg
     3001 ctagtctcct aagtcccttt gtagcggata tggcaccata atctcatttt atcgaagtga
     3061 gtcatggttt atctgttggc caaccaaaat tgatacaatc taacgatgca ccctctacgg
     3121 cattctaggg gagtgcactt gcattcaccc aataaaaacc ggcagttagc aaagaactta
     3181 tgtagtcgta tgttcttact gttaacatac aagaggtctc ctttccacaa ttgcttagca
     3241 gtaaacggga atttacaaag ctaatctctt ccattttctt atctttgttc taaaagtccc
     3301 aaatggagca actgtattta catgaataaa tttatatact tcccatacag ccgttttggt
     3361 tgcctcgtct gcccattttc ttttgtgtgc agtgaataga tcttcatcac tcattgaatc
     3421 aatcatcatg ttaatatcat caatattacg attgagaatt tcctctaatt ctttcaatgg
     3481 tagatgtgca taggtatttg taaaccactt atataactct cctaactgat tccatttaaa
     3541 ttgatcagaa ggcgttttaa cagataatcc atttctttca tcattttccc attttagaat
     3601 taaattcgtc caaccaactt gatatgctaa attttcagca ggtgttctat ccacttcctc
     3661 aactctttta tccttcaatt cttcaggaat agtttcaaat tctaaaatat atttagtata
     3721 agtcctattt atttcttttt ttaattcttc tttattttta tatgttctca ttatattacc
     3781 tccataaatt cctaattgtc tcctttaatt catctataat ttcatccacg atattttaat
     3841 ccgttctaca atgcatatct gatatgcatt gactgtctaa ctcatatgtg aatgatttat
     3901 aaaatatccc aacgtctcat ctaaagaaat gttgatcgtc agcaaggagc taaaaaatac
     3961 gaatatattt cttttgtagt aaaatcggac tggtttgcat atcattttct tcgtaaatat
     4021 caaaatcatg ttaactacta tcaattacta ataaaaacta ccactttaag cgttaagaac
     4081 tgttaagttt agttaagtga ggatagttca caaaatccat tgttaaactt cacgaaagtg
     4141 gtaaaactca aaatgcttta tataggatta cagcatcgct ctttcttcga ttgcgcgttg
     4201 ggtaaaaaat attatgaagt aaaaattgac gatgacacgt tccttacggc tcatcagatg
     4261 aaacagctac aaaaacgaaa tgatcaactc gaagaaaatt taattctaaa aaagcgattg
     4321 ccatattcac gcctcgctcg acgaactatt aaaggtcaag atttacctga agatcatcct
     4381 ttttaggaaa ttgaagcttt ttatgttgca caatgcattt ataatactac aatgatgttt
     4441 tcaccagata ttcttctagg gtgcggtgta atgaaacaga tacacttgca aaagaaaatt
     4501 caccgcgaat ttactaaaat tatgaataat tatgttaatc ttccgaaatt tttttccaaa
     4561 attaagggat caagctggtg ttatagattg tttaaggttg gcaaaaaaat aacttctttt
     4621 taaacaatta tagaaaaccg atactctgtt aagttggttg acacggtgtc gatttttatg
     4681 actttcttat tctgaaactt cactaacgga cagtacctaa aaagtctata gtatggacgt
     4741 ttacgagtac tattttatca aaaatgctgc tcatttcaac ttatatgttt tagtgaacta
     4801 cccccactta g
//
LOCUS       DAZKCW010000115         4730 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000115 DAZKCW010000000
VERSION     DAZKCW010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.121"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..527
                     /locus_tag="ACG84Z_002686"
     CDS             <1..527
                     /locus_tag="ACG84Z_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFP9163477.1"
                     /translation="KQYRTKGIAYFSKEDFHELLDIPKSYRESVINKKIIKPIRQELT
                     AIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEEQNKALELVNQQI
                     YSEKDPTSLQEKIKEQKRKLELLQQLEELERKQNNLNKENKEINEQIPDNNSDIPPEL
                     KKGLLDNLQNLFKE"
     gene            537..1034
                     /locus_tag="ACG84Z_002687"
     CDS             537..1034
                     /locus_tag="ACG84Z_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFP9163478.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNIIYLKKE
                     AVTTITKVLSGNEPGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQLALETQ
                     QKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIEKQSKTEKKW
                     WQFWQ"
     gene            1410..1691
                     /locus_tag="ACG84Z_002688"
     CDS             1410..1691
                     /locus_tag="ACG84Z_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163479.1"
                     /translation="MDILVRKIDSKIISEIDRRCQELTTKTSKKWSRNTYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNEYVRTNNQLIETLIGGL"
     gene            1693..2109
                     /locus_tag="ACG84Z_002689"
     CDS             1693..2109
                     /locus_tag="ACG84Z_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163480.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISILSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNHQKETNQTFTAGNFDPTNFLKR"
     gene            2767..3192
                     /gene="bacA"
                     /locus_tag="ACG84Z_002690"
     CDS             2767..3192
                     /gene="bacA"
                     /locus_tag="ACG84Z_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin 51 precursor BacA"
                     /protein_id="HFP9163481.1"
                     /translation="MICKNKKKIIAIIASFSLIFSTACTVLLTNNANVEAASSSYKHN
                     HAGYRCYKMSYYVSPSKCKQLARQTNKLNTVSAIANFIGLSGLTPGIISLVFGSAVSA
                     NNVFVTAARRGKGVQLNYIAHFSNTTTYNYSSNQNYVIK"
     gene            3222..3386
                     /locus_tag="ACG84Z_002691"
     CDS             3222..3386
                     /locus_tag="ACG84Z_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163482.1"
                     /translation="MKLTKIAVILAVIAGIILYFVLPANQFFLYFGIPAILIVNGVRI
                     FEQRKKCSST"
     gene            4280..>4730
                     /locus_tag="ACG84Z_002692"
     CDS             4280..>4730
                     /locus_tag="ACG84Z_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFP9163483.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRL"
BASE COUNT         1743 a          810 c          785 g         1392 t
ORIGIN      
        1 taaaacaata cagaaccaaa ggaattgcct atttttcaaa agaagacttt catgaattac
       61 ttgatatccc taaaagttat agagaaagtg ttataaataa aaaaattata aagcctattc
      121 gccaagaact aaccgcaatc ttcaaaggtc tgacaatcaa aaagaaatac ggaaaaggaa
      181 gaggaaaacc tgtcattggc tatcaattca cgtttaaacc tgaaataaaa aaagcagacg
      241 actttaataa acacgcacca acaaaagaag aacaaaataa agctttagaa ctagttaatc
      301 aacaaattta ctctgaaaaa gaccccactt cattacaaga aaaaatcaaa gaacagaaac
      361 gaaaattaga acttttacaa caattagaag agctagaaag aaaacaaaat aatctgaata
      421 aagaaaataa ggagattaac gaacaaatac cagataacaa ttccgatatt cccccagaat
      481 taaaaaaagg cttactagat aatcttcaaa acttatttaa agaataaggg gtttttatga
      541 cagataaaac tatcaaagaa ttagcagata ttctaggtgt ttcaaaagat aaagtgaagt
      601 atcaactgag gaaattacct agtaatttta cctacaaaaa aggaaatatt atctacctga
      661 aaaaagaagc agtaacaaca attacaaagg ttttatcagg taatgagccg ggtaacttac
      721 ctagtgaatt acctgattca ttacctaccg attacctact caaggagatt gaaactaaga
      781 ataatcatat tgaagaaaaa gataggcaaa ttgaaaaact tcaactagct ttagaaacac
      841 aacaaaaatt actcgaccag caacaacaac tcaccctgca agccaaccaa caaatcgaga
      901 aactgcagga acaactacag ttgacttata cggaagaatc ttcggaaaat aaatcaacga
      961 ctctttctga agaaacagaa tcgatagaaa aacaatcaaa gacggagaaa aaatggtggc
     1021 aattctggca ataaaaccag caatttaaat taataaaaat tgctggtttt attcttcttt
     1081 ttgcttttgc gagcagagca acatgggccc atgttgcgat attttggtgg cgccccaatc
     1141 cccgtttttt cgttgaatct tactcggact gcactcgttt tacagctgat ttttctgaat
     1201 tttgaaagag cataaggaaa cgtggtatca ctttcttacg aaaggtgcta gataagctgt
     1261 gcctatcacg tttctcagaa aaaaatttgc tatcactttt ttgccattat ggatagtgta
     1321 tgtatagtat tttggtaaaa aacagctata caaatactat atttgtatga tatacataga
     1381 ttatacgcac atgcgaaagg aaaattgcta tggatatttt agttcggaag attgattcaa
     1441 aaattatttc agaaatagat agacgttgcc aagaacttac aaccaaaacg agcaaaaaat
     1501 ggagccgtaa tacgtaccta aaagttctaa tcgaaaatga ttttgaccag gcacttaggc
     1561 attacaaaaa agatcaattc gatttattac tcgaaaaatt tatcgatata caagcaaaaa
     1621 atacggaaac actgaatgaa tatgttcgta caaacaacca actcattgaa acacttatcg
     1681 gaggactata acatgagaaa aacttctgtt caaaaacacg ttacccttta tcccagtcac
     1741 gtggacgttt tagattccat tattgaaaga aatccagata tcaacaatta ctcggaagcc
     1801 attcgttttt tatgtatgag ttatgaacct gataccaaca caaccactac tagcaaccaa
     1861 gccaaactaa atgctatggg aaaagaaatt tctatcctgt ccgaaatcat tgcagaattt
     1921 gctgatttat atctaaaaga tactggtgtt cttattggta ccaattctaa ggtgtatcaa
     1981 gaagtgaaag aaaaaattga aaatcaactc aatccttccc gacgaaatca acccaaaaat
     2041 catcaaaaag aaaccaatca aacattcact gctggaaatt ttgacccaac caactttcta
     2101 aaaagataaa aacagaacct gaaaaataaa aaaattcctc gatttctttt tagggggggc
     2161 ggtcttccag caagatttgc aagttgggac caacttgcgg aaaaaaagaa aaattcgctt
     2221 gcgcgaatcc ttctttttgc attttggggc gctgccccaa tccccaagta tcggttattt
     2281 aatagcgtgg caactcaaag aacagaacat actctgaaac aaaaaaagac tgctctaacg
     2341 agcagccagt taaaaaataa tgagtgttta ttcttgaaaa agcaacgcgc ttatgaagcg
     2401 ctaccaaaaa attatcatat tttattaaaa ataacaaccc agtaaaaaat gactggtaaa
     2461 aattcacaaa gaaacggaaa gaagcaaccg cagaaaatca agcttaaaaa gagcttttga
     2521 cctagaccaa tgaaaaatca caaagtccgc ccctgtacct gttggtagct gggctacttg
     2581 gcatactgta cattatgtca acaagaattt aatataacat atttttctag tttgttataa
     2641 caatgccact ctaacaaaaa tgtaagcatt atccttatta aaagctcctt gacaagacta
     2701 taccttttat tttatgattt ttacatagaa aacgttttct ctattttttg tttagaggtg
     2761 atttttatga tttgcaagaa caagaaaaaa attattgcta ttattgctag tttctctttg
     2821 atttttagta ctgcatgtac tgtcttatta acaaataatg ctaatgttga agctgcaagc
     2881 tcttcttaca aacataatca tgctggttat agatgttaca aaatgagtta ttatgtaagt
     2941 ccttctaaat gcaaacaatt ggctcgccaa actaataaac ttaataccgt ctcagctatt
     3001 gcaaacttta ttggactatc tggattaaca ccggggatta tatcattagt tttcggatca
     3061 gcagttagtg ctaataatgt atttgttaca gccgctagaa gaggaaaagg cgttcaatta
     3121 aattatattg cccattttag taataccact acctataatt atagttctaa ccaaaattat
     3181 gttataaaat aattaaaact ttaaactagg aggaatgctt tatgaaatta acaaaaattg
     3241 ctgtaatttt agctgttatt gctggcatta ttttatattt tgtattgcct gctaatcaat
     3301 tcttccttta ctttggaata cctgcgattt taatagtaaa tggcgtaaga atctttgaac
     3361 aacgaaaaaa atgtagctct acctaatcgt tacaaaacaa caatttcacc ttcggtgaaa
     3421 taagcgaaac tttacaaaaa gtggctagca aatgctagcc ttttttgtat tgtagagcgt
     3481 gaattttgag ggggattcaa gggggagctt gcgccccttt gacaagcggt tatttgcacc
     3541 aaatacctcc gtatttggct agcaatcctt ctaaaaaata cacctatcga tcagagtcaa
     3601 aacaaatcaa ttttcgagtg agcgaatccg aatttgcaaa gctgaagctt tgcaaatgag
     3661 tgtgccggct tccgtaaaaa tacatatggc tataatttgc gttttaaggc gttttaaacg
     3721 ttctggtata taaaattata ccaaaacaac tttaaaacgc cttagatcta attttagagg
     3781 tcttatagaa cattttaggg ttgttagggc ttgccctgac cgcctgtaag gcgctttgag
     3841 aacaagataa gggttttata ctaagactgt cttaaaacgg cttaaacaaa cgctcagaac
     3901 ttttcaaagg agttctttat gaactgtttt taagcaaagg agcctttagg cgactgcgca
     3961 gtataatgtg agagcgtagc gatcacacat ttttagtgac cgtagggagc gagtttccca
     4021 gtttagaaaa attcgcgaac ttgtttgagg aaaaaagcag gagtttttta ggcgggaaat
     4081 tttgcctcct cttttataat ctctttttaa acctcttttt aaacctcttt accgtcggct
     4141 gtatgcttac tctcccaagg tgtgcagaat cttttggggg tctttttgtc tgtttttagg
     4201 ggtctttaat taggggcttg acccctatta gaaagctctt tataattttg ttaagtagtt
     4261 aatcttgaag gaggatttta tggcaaatga aattgtgaaa taccaccatg aattaaatac
     4321 gattccttta cgcaaattta cgtcagtaga aatgaattta ttcttctcta tagtatctag
     4381 aatgcgtgac gtaggcgata aaaaagtaca atttacattc gaacaattaa aagatttaag
     4441 caattataaa gcaactgcaa atgttcgatt catagatgat ttagaaacaa cgtatgacaa
     4501 attaatggat ttacgttttg gtagaagaag tgctgacggt ttgcaacgtg aacgatttgt
     4561 tttatttaat caatttaaaa tcgatggaaa agctgatatt ccttttgctg aaatacaagt
     4621 ccatgagaaa gccttaccct tacttaataa tcttgaagaa tgggttcgat attctctcca
     4681 acaattcaat gaattagaaa gcagttattc caaaaccatg tttagattat
//
LOCUS       DAZKCW010000116         4729 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000116 DAZKCW010000000
VERSION     DAZKCW010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.122"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            95..1054
                     /locus_tag="ACG84Z_002693"
     CDS             95..1054
                     /locus_tag="ACG84Z_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="HFP9163484.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINF
                     LKEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPIS
                     CSVRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEF
                     GHIEGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFK
                     SITFDCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQ
                     VDQAFISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
     gene            complement(1487..2059)
                     /locus_tag="ACG84Z_002694"
     CDS             complement(1487..2059)
                     /locus_tag="ACG84Z_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9163485.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2075..2680)
                     /gene="fic"
                     /locus_tag="ACG84Z_002695"
     CDS             complement(2075..2680)
                     /gene="fic"
                     /locus_tag="ACG84Z_002695"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFP9163486.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(2860..3597)
                     /locus_tag="ACG84Z_002696"
                     /pseudo
     CDS             complement(2860..3597)
                     /locus_tag="ACG84Z_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336528.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(4040..>4729)
                     /locus_tag="ACG84Z_002697"
     CDS             complement(4040..>4729)
                     /locus_tag="ACG84Z_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnsA endonuclease N-terminal domain-containing
                     protein"
                     /protein_id="HFP9163487.1"
                     /translation="YQYSNLTLIAEIARYLNFSPLEVQRILTESQDGLEQILFWSNTY
                     KQVVYEILIPKIFEYKFKITKSQITEDNEVVLLKFPQGKNYYKFSGKPELVIMDSDKQ
                     LENYKTKSFHADTYVFDSKPERELFLQYLENDTVEEIFFTGMFTSKQGDFYIQYIDPE
                     ANSVRSYFPDFVVKKRDGSREIIEVKGDNKKDDPVVLAKKAATEEQAGQSGYSYRMIL
                     GSEIMNNNYEI"
BASE COUNT         1436 a          916 c          804 g         1573 t
ORIGIN      
        1 gccgattgta aaattaagct agacaaataa ataagccatt cgtgctacac tcaaaatgta
       61 attccgacta aagaaaacat aggagtgatc acgaatgacc tacacccatc ttaccacgga
      121 tgaactggtg atgatagagt cttactacca ccaaaacatc aaaattgtga aaattgctga
      181 gtacctgaaa cgatctcgaa caccgattta taacgtcatt aatttcttga aagaaggcca
      241 tacggccctc gaatactacc aacagtataa agaaaataag aaacggtgtg gcagacgaaa
      301 catcgtcttg ccaaagaaac aacagtccta cattaaagaa aaaattgccc aaggctggac
      361 gccagacgtt atcattgggc gtaaagagaa accaatcagc tgttccgtaa gaacccttta
      421 tcgccagttc aaggaaaagg tgttcgatga atcgactttg cccatgaagg gtaagcggaa
      481 accaaatgga catcaagaac gccgaggaaa acaggctttt aaacggaata tcgttgaaag
      541 agaaactgat tacccgacat ttaaagaaga gttcggccat atcgaaggcg ataccattgt
      601 aggcattcat cataagagtg ctgtcataac tttggtagaa cgtctatcga aaatcatcat
      661 caccttgaag cccgaggggc gcaaggcgat cgatattgag aatactctga accactggtt
      721 tggatcgatt cccagacatt tatttaaatc cattaccttt gattgtggga aagaattctc
      781 taattggaag gctttaagta accaacatga catcgctatt tatttcgctg atccagggac
      841 tccttcgcaa cgagcactga atgaaaattc caatggcttg ctgcgaaaag atggtctgcc
      901 aaaaaacatg gattttaatc aagtcgacca agcttttatc tcttcagtgg cgaataagag
      961 aaacaatatt ccacgaaagt ccttggatta tcaaacaccc ctggaagtat ttatgagtta
     1021 catgaatgaa gatattttgt ctagcttaat ttgacaaatc aaattattta aaactttgca
     1081 acagaacctt agcagcagtg ctgattttta tgatagttat ttggttctta aatgaaagat
     1141 ctaaagacaa tcaacaccgt agggatatgg agataaaatc aatagagtca atagattatt
     1201 tatcgataat aacactaaaa aagccacgtt cctaaacgtg acttacgctg aacgatatgt
     1261 gttgtttggt agacgaacaa atcgttcatt ataaatatat gatggtatcc taatatagta
     1321 agcgtggcta gcataccttt aattacttta ccttttacag ttaccataca cattttttga
     1381 gcagaaatca agtaaataaa aaaatattat atttcacaac atgctaatag actcatatct
     1441 agaacgcatt aagtatttac ctgtctggtt cgctgagact tcttttttaa ctttcttcaa
     1501 ttttcttctt tattctaaaa agcgtactgc gactgaaacc ggttatagct tcaacttcct
     1561 tatacgattt acctgaagta agcagttcat atgcgtgcct cttcttcggt gtgattgttg
     1621 ctttcggacg tccttctctg aaattaggat tattctttct tgcaaacatt tttccttctt
     1681 gggtacgttc cacaatcata tcacgttcca tttctgctac actcaacaac gtccgtgtca
     1741 ccattcgccc catggacgta ttttcaatcg ttcctagatt caaaaccttg atcgttacgt
     1801 tatcatcgag taaaggttca atgatctcta atgcttctct cgtgttacga gcaaatcgat
     1861 caagcttcgt aacaactatt tcatctccag gcttcagacc agccaacagc tgattgaatt
     1921 ttggccgatc ccgttttgta cccgtaaatt tttctgaaaa aatattcttc ttctctacgc
     1981 cgttctcaag caactgttga atttgttctt ttgtactttg agaagcggtt gagacacgtg
     2041 catatccata tttcgtcatt tggtccacct acttttacaa atcatctatc gtatactcag
     2101 aatacccttc atagaaatag ctgacatcga ttcctttcat atataactcg cgatcgtcaa
     2161 ttttatcagt cagagcattg gaaattagat agcgtatttc caaatcgttt atgggacttc
     2221 gctccattgc agaaagatag tctgctttat cgattaagtt ccaatctaca actttttgca
     2281 attcttcctt taaaatgaga tccagccaaa ttctagtact tcggccattt ccttctcgaa
     2341 atgggtgagc gatattcatc tccacatatt tcttgataat ctcttcaaaa gaagtttgtg
     2401 gcatctgatc aatatgctgt aacgaatgtt ctaaatacat aactggtgca aatcgaaaat
     2461 ttccttttgc aatattgacc gatcggattt ttccggcaaa atcgtaaata tccgaaaata
     2521 gaaattcatg aatttcagat aaacctttaa atgtaccaac ttcgatttca tttatttttc
     2581 cacaatcgta caattctttc gctttttgtt tactgagttt ttcttcaacc ttagccaact
     2641 caacttgatt ggttaatccc aatttattct ctaaaatcat gcgaaatctc cttaacttta
     2701 tgacataagt ttatgaaaca ctctcaaccc cattatatcg cgattttgtt tatgtgtcaa
     2761 aaactattaa gtttctgacc ctctacaaaa ttcacaatag atataatcta ttgaaaattt
     2821 aaaagaagac aaaatagagt acagaaaatg ttttctgtac tctataaatg attctgatac
     2881 ttcattgaag tccatggctt taactaatcc atcacgacgt aataatccat ttgaatgttc
     2941 atttagagcg cgttgtgacg gggtgcctgg atccgcaaaa taaatatcaa tatcattttg
     3001 atttcccata gctttccaat ttgaaaattc tttcccacag tcaaacgtaa ttgatttaaa
     3061 cagatgttta ggaaccgttt gaaaccaatg attaattcga ttttcaatgt ccattgcctg
     3121 tctaccggct ggcttcaatg taataatcac ttttgacaaa cgttccacca atgtaataac
     3181 agcacttttg tgttttcgac cgacaatagt gtctccttca agatggccaa actcgttttc
     3241 aaattctgga tgctccttga tgcgctcatg tatactgcgc cgaaaagctt gtttcccacg
     3301 tttttcttgg tgtccatttg gttttcgttt gcctttcata ggcaaatcac gcacattaaa
     3361 tgcgccagtt tgaaacattc gatacagtgt acggactgaa caatcaagtt tcatttccga
     3421 gcggccgaca atcacatccg gtgtccaccc ttgaacaacc ctcttttgaa catattcttt
     3481 ttgttcctct ggtaaagcaa tcgagcgtct accgcagcgt tttttgtttt ctttgtattg
     3541 ttgatagtag ttcagtatcg tagcaccagt tttcaaaaat tgatacacgt tatgaatcgt
     3601 ttgtcacgca cgtcctaagc attgcgcagt tttggcaacg gattgattat ttttgaaata
     3661 agactctatg attaccagtt cgtctgttgt aagatgggtg taggtcattt gtactcactc
     3721 cttaataatt ctttggtcgg aactattttg agtgtagcac aaatgatctt tttagttgtc
     3781 tagcttaatt ttacaatcga cgaaaagaat actatgatga gattagtttg aaatttcatt
     3841 ttgatgagta gatattagga actgattgat agaacgaata agttatattg atattttgta
     3901 tttgcagtat ttgaaaaagt tgaagatgat aaggaaaata aagaaacaac aggaacagtc
     3961 taacttgact attcctgttg ttgaaaagat tatgattaat ttactacttt attttttata
     4021 gacatgctat ttacatactc tatatttcat agttgttatt cataatttca cttccaagta
     4081 tcatcctgta tgaataacca gattggcccg cttgttcttc tgttgctgct tttttagcta
     4141 ggacaacggg atcatctttt ttattatctc ctttaacctc gataatttcc cgacttccat
     4201 ctcttttctt gaccacaaaa tccggaaaat aactacgaac agagttggct tcgggatcga
     4261 tgtattggat gtagaagtct ccttgtttgc tggtaaacat tcctgtaaag aatatctctt
     4321 cgactgtatc attttctaga tattgtaaga aaagttcgcg ctcgggtttt gagtcaaaca
     4381 cataggtatc ggcgtggaag ctctttgttt tataattttc taattgctta tctgaatcca
     4441 ttataaccag ttctggtttg ccactaaatt tgtagtaatt ttttccttga gggaacttca
     4501 agagaacgac ctcgttgtct tctgtaattt gagatttagt tattttgaat ttatactcaa
     4561 atattttagg gattaatatc tcataaacta cttgtttata ggtatttgac cagaagagaa
     4621 tttgctctag tccatcttgc gattcagtta ggattctttg tacctctaga ggactaaagt
     4681 tcaagtatct ggcgatttcg gcgattaaag ttagattgga atattggta
//
LOCUS       DAZKCW010000117         4425 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000117 DAZKCW010000000
VERSION     DAZKCW010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.123"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            690..1658
                     /locus_tag="ACG84Z_002698"
     CDS             690..1658
                     /locus_tag="ACG84Z_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9163488.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="ACG84Z_002699"
     CDS             1669..2484
                     /locus_tag="ACG84Z_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HFP9163489.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="ACG84Z_002700"
     CDS             2552..3262
                     /locus_tag="ACG84Z_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFP9163490.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4425
                     /locus_tag="ACG84Z_002701"
     CDS             3298..>4425
                     /locus_tag="ACG84Z_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFP9163491.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKML
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1488 a          662 c          922 g         1353 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgcacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaaa aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatgttatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt tttgatttca aggagtagat tttatttatg
     3301 aagcaagtat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatgct tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaat
//
LOCUS       DAZKCW010000118         4419 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000118 DAZKCW010000000
VERSION     DAZKCW010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.124"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            228..842
                     /locus_tag="ACG84Z_002702"
     CDS             228..842
                     /locus_tag="ACG84Z_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9163492.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            complement(866..1216)
                     /locus_tag="ACG84Z_002703"
     CDS             complement(866..1216)
                     /locus_tag="ACG84Z_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFP9163493.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(1210..1473)
                     /locus_tag="ACG84Z_002704"
     CDS             complement(1210..1473)
                     /locus_tag="ACG84Z_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HFP9163494.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            complement(1814..1993)
                     /locus_tag="ACG84Z_002705"
     CDS             complement(1814..1993)
                     /locus_tag="ACG84Z_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163495.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            complement(2009..2209)
                     /locus_tag="ACG84Z_002706"
     CDS             complement(2009..2209)
                     /locus_tag="ACG84Z_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163496.1"
                     /translation="MNKIIPLLFVLFVGEILMRHAAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            complement(2374..3081)
                     /locus_tag="ACG84Z_002707"
     CDS             complement(2374..3081)
                     /locus_tag="ACG84Z_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163497.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            complement(3074..3511)
                     /locus_tag="ACG84Z_002708"
     CDS             complement(3074..3511)
                     /locus_tag="ACG84Z_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163498.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            complement(3526..3777)
                     /locus_tag="ACG84Z_002709"
     CDS             complement(3526..3777)
                     /locus_tag="ACG84Z_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163499.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            complement(3777..3983)
                     /locus_tag="ACG84Z_002710"
     CDS             complement(3777..3983)
                     /locus_tag="ACG84Z_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFP9163500.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT         1290 a          856 c          714 g         1559 t
ORIGIN      
        1 aaaatatatt tttaatgtca taatcgttta aattttcttg attgacattt atttacaaaa
       61 aatattgcca tttaaaaaga aaagtgacac atactatttc ctccatcatt agtttttgtc
      121 tatataaggt ataccctaac tagacacgac cgcgacattg aaaaatctgg ttttctcgtg
      181 tatgattagg gtgtttttta aatagttgca gaaagtaggt aaaaattttg agagttgcat
      241 acatacgtgt ctcatccatc gatcaaaatg aacaacggca gattgaagaa atgaaaaaat
      301 tcggtgcaga gagaattttc attgagaaac aatctggcgc aacgattact catcgacttg
      361 tttttcaaga agcactggat ttcgtccgag atcaagatat ttttattgtg gaagctattg
      421 atcgacttgg aagaaattac gacgagatca tcgcttcagt caattacttg aagaagaaaa
      481 atgtgcagct gatcatcaca agtctaccga tcatggccga agcaattggc aatcctctcc
      541 tggataaatt cattaaagat ttgatcattc aaattttggc catgatcgct gaacaagaac
      601 gtaccgaatc taaacgacgt caggcacaag gcattaagat tgcaaaagcg aacggtgttt
      661 ataaaggacg tcctaagcta tacagtgcca atgcaaaaga tccccaacgt cgtcttgttt
      721 ataaaaacat cgttgaggat ctaaaaaaag gtgttgcgat cgctaagatt gcaaaagact
      781 acaatgttac gagacaaacc gtatatagaa taaaaaaaga cagcatggtc aatcacgaat
      841 agttgatcat gctgctgttt ctattttatt tgcttacttt ttgaaaaact gttctaactt
      901 tcatcaataa ctcctcaact aaactatcat gcgctttttc caaaaaaata cactctctgg
      961 cttcataatc aattgtcgtt agttgatcta ataatacttt tcctgttgtc ttcatttcat
     1021 attctgagtt tatatttaca tatagcggat agtttctagt tgtactagaa attggagcaa
     1081 ctgtaacaac gttactataa tccgcaataa tatcatgact taaaacaata taaggtcttt
     1141 tacctgtctg ttcgtgtcca gatcgaggtg ctgtattcaa taatagaata tcgccttgtc
     1201 taggttttct caccattttt cattacctac tgcttcacct aaattttgaa tcgtcacatg
     1261 atttctttca tcagtgtaat tttcaaataa ctgttcaatt gttaattcat tttctatatt
     1321 agccgcttcg ataattagcc gcttctgacc gtttacttct tcttgtatta tcttcacttt
     1381 gtcttctgta tgaattccaa gatattccat aatatacttt ggcaatctaa ggccattact
     1441 atttccccat ttttttatag gtaacatttc catagtagac acctctttct gtatatacat
     1501 agtataacat acataagaaa aaacgtatat acttaattat ccttttctat taaattagat
     1561 taacattcca tgaatccata aactatgtta acatttatat gaaaatagtc gaaaggaaat
     1621 cataatatgt ttaagaaaac aaaatcttta gaatcaggta agaaaaaaat tgatctaaaa
     1681 ataatctctt ctggatactt taaagatttc atagttattg atacaaaatg gaataaaaag
     1741 gacatagaaa atattctaaa tagtaggaac aattaagtgc tatcactttt gtttcttcaa
     1801 atgaaaagtg acgtcacttt tttagtgctg gtatatcaaa tcctgctttt tcttgcgcga
     1861 tcaatagatc taacgcaata cacataatct tagattcact ttttccgtac ttctgcttta
     1921 gttgctgcaa ttctttttgt ctcttttcat ctaatgtcac gggtaaccgt ttatttccta
     1981 ttgcaattgg cattagtact ctctcctttc atcgaaataa ccctatgaaa aatatggctg
     2041 caatcatctt gaatagtaga ctcacaaggg ctaatacaaa tcgccaaaag atcaaacaaa
     2101 ataccagtat tcctaagaat actacgaagt ttaaatgtac agctgcagca tgacgcataa
     2161 gtatctcgcc aacaaacagt acgaacaata gaggaatgat tttattcata tggatctcct
     2221 tctttctctt aggttatcgg gctttgcccg cttatttcgc accacctaag cggcgggggc
     2281 ggttggagcg attggtgcga aataagaacc attcccttaa tttcaaggtt ttttgttctt
     2341 atttcacaca tcctcacttt tcggtataaa tggttattta ccttttttcc tttcaaatcg
     2401 ttgatatggc attcgtttac ggtcaagttc attttggatt tcttctgtat cgtcgtaagt
     2461 gtaggtgtct aaaaaatcag ttaaagtcgt gtaccagtcg tcgcctgggt tatctacttc
     2521 ttctacatat tccctcaaaa atgcttcggg tacagcgagt tcataatcca ttcccattaa
     2581 cacgatagat tccgtcccac acgtcaaaaa cctagtaaat acaaggtaat aatcgtctac
     2641 cgtcgcattt ttgctgttta gctcttccat ttcttcttcc attaattcca tgctctcgaa
     2701 aattgaataa tattctgatt ctgagtaata gtgtttccta caaatcgtgt agctgacaaa
     2761 gttttcgacc agctcactcc tttctaggta cacattcatg atgtattttt ctgtttctag
     2821 tcgtagaagc tctgttcctt tttttaccgt ttcaggacga cgtttataca cgtctaaatg
     2881 attatggctg actgtgacct tcgtttgact tgtttcgctt tccatataca actgttcttc
     2941 cactctttga ataaagtact tcatttcttc catacaacta aagtcttttt gaatccgtct
     3001 gattacttca ttcaagtgtt ctttgcttgt taaaaattgc gaaacatctt ctgttgttag
     3061 ctgataaacc accttattca ttatctttct cctccgattc aatcgtataa aatgcaccat
     3121 ttttttcgat actttcaaaa gtatctagcc agtcgctagc cattgcttta gctttcttaa
     3181 tctgtgcgaa ttttgcataa gtcagttcta aggcttgata ttcggaaggt ttgatagtgc
     3241 ttggtttgac acctacttcc aagcatagta aggcttggaa aaaccatttt ccattttgtt
     3301 ttttcagttc ttccagtgtt cgatagtacg tcgcaatgag attcatttcg acacctgatt
     3361 caatcatttc ttccactgcg actgacaatt tttccttgta atgttttttg ggtacacgtg
     3421 tttcatggta taggaacgtc atatcctcca ttttttgtgc cattttatcc aaaggtaatt
     3481 tgacaaattc gtcatagtaa ttttgagcca tattttttct cctttttagt tctctaattt
     3541 ggttaaccaa tattcgattt cataagtttc catgttttct tgataatgca gttcatatcc
     3601 tgcaatcttc actaggtctt caaatagcat agtcggtgca tcctctacta aaggggtttc
     3661 tatcgtccag taccgcggaa taagtaaagc ttctgctact ttttcagaaa tgacttcttt
     3721 gtccaccaaa atttgaacga cttcttttac agtcaataat ttgtgttgtg ttttcatcag
     3781 cgtttctttc ctttctcatc aatcaaaatg taatcgccat aagacaaggt atattttttc
     3841 ccgcatgttg gacattgata caaacgatag cttttgatac atttcgctct ttctccacaa
     3901 tcgcattcaa cagtatgtgg tgcatgatag tttgggaata attcgctgaa gggaacaccc
     3961 caataatcaa atttctttcg catgtttgat tctgcctcct cttaggaaag gttttacttc
     4021 ctttcgttag ttctttcttt attgatttgt tggccagaat aaatcaacga aaagcgacaa
     4081 ggacaagggc gcgcagcgtg ccatttaccc ttgtccttgt cgctttttgg tgataaaagg
     4141 caacttgttg ccggtctggc aaatcaataa agagataacg aacaggaacg aaccttttgg
     4201 tgagaggaag ttttgtctat tttgtcttgc tttgcaagac accatatctt agtgaacgtg
     4261 cagcgttcac ttcctttctt ctcgaacggc ggtggcggtt ggagtgagag aaaggttttt
     4321 caattgagaa ggcacttgtg tcttcctaaa aaggtctttt cctgtttcta tgtaaaacaa
     4381 aaagagctgc aatcctcatt taggactaca actcttctt
//
LOCUS       DAZKCW010000119         4385 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000119 DAZKCW010000000
VERSION     DAZKCW010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.125"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(218..1129)
                     /locus_tag="ACG84Z_002711"
     CDS             complement(218..1129)
                     /locus_tag="ACG84Z_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFP9163501.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1283..1435
                     /locus_tag="ACG84Z_002712"
                     /pseudo
     CDS             1283..1435
                     /locus_tag="ACG84Z_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            complement(1555..2163)
                     /locus_tag="ACG84Z_002713"
     CDS             complement(1555..2163)
                     /locus_tag="ACG84Z_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFP9163502.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(2169..3200)
                     /gene="vanA"
                     /locus_tag="ACG84Z_002714"
     CDS             complement(2169..3200)
                     /gene="vanA"
                     /locus_tag="ACG84Z_002714"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFP9163503.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(3193..4161)
                     /locus_tag="ACG84Z_002715"
     CDS             complement(3193..4161)
                     /locus_tag="ACG84Z_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFP9163504.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         1227 a         1001 c          769 g         1388 t
ORIGIN      
        1 aacactaacc agattagtgt cactaaatat aaagctagca atcctctaga taatattttt
       61 cccaatataa tttcctctaa ttcttttgtt taagttgtat cattagtata gcaatgtcct
      121 agttaacgtg ggttttaaat taaaaagcta acgttacccc aaaagtgcta gtacaataat
      181 gctgttcatt aatttcgttg gtttcattcc gccatcctta cctccttgaa ttagtatgtg
      241 ttgatccggg aaacactgtc acaattacac cgtctatatt gtttcctgat atctcataac
      301 gaagattagt cggcacatga atggtggtat ttttagtaac aggataataa aagatctcat
      361 atttttcccc atttacacta acagaaatgg ttttttcttc ttttaggtaa tccatatatt
      421 cctcgagaac gaaattcttt tctttcataa tcgcactatg tggtaaacca acatagcgaa
      481 tatgccatgg ttcatattga attcctgtta actctgtttt gtcctctgga taacgtaaaa
      541 tgaacccgta tttccaagca ttttcttcta tccactttcc ttcaggggct cgttccattt
      601 tcgtcaagct tgatcctaca tctagtgata aacctgaatt atgctcacta taacctgctg
      661 gtaaggcata ctcagccccc atttcttggt aaagcacact ttgctcatca aagtctcgat
      721 agccactatt aataataaaa tgactaacgc caccctttac agcatcattg accatctctg
      781 aaaatttttg tgctatttct tttgacatat aaatattact atcaagcaac ccgtatccat
      841 ttattaattc gtcatgttta gataaattca cgatatctga cttcacactt tcttggcgaa
      901 caggatattt actattgatt aatagcagat ttccttgata aacctgttct tctgtaattg
      961 ttttctcttg ggtattttca gaagtcccac tattttctaa atgttctttg ggattttgat
     1021 cataattttg aaattcgact ttttcctgag aaaacagtgc ttcattaacg tagtcataac
     1081 ctaagtatat taagaataac aataacaata aaaaaaacaa cttcttcatt ttcagtctcc
     1141 tccttaacta tatagttgga agtatgaaat atttctagaa tcttcccctt aaacggcaca
     1201 atctcgtttg agattgtgcc gttttgcccc gtaaattaca gtcaattatt tcgccctact
     1261 ggatttacta ttatcaccaa tttccttaga aaaattaggt tgtcaaaatt tcaactcacg
     1321 ttctgttaaa gggctagaga gtagatttga aagcatatta ctggcttaca gtgttctatt
     1381 aagtcgagca caacgacgtt ttgaaggaac tttgagatat tctttaggat attaaaatta
     1441 actagcacca cgggttatct actatatata aattccctaa gaaccagtta catacgtcgg
     1501 gtttcctgcc gaaagagtta gcttatatag tttgtccgtg caacggttaa aagtttattt
     1561 aacggggaaa tcaaaatagc tattggggta tggttcgtct cttaatacat agtgccacca
     1621 ttcgaggcta tatgcttcaa acccactgtt ttccatgatg gagcgcaaac gtctgcgatt
     1681 ttgcgcttca ttgcatgata ttccatttgc cgcatgatga gagcgttcat ccataaaatc
     1741 aaatcggctc cccattggta caagctcacc cgtgtctaat cgataaagcg taagatcaat
     1801 ggcactgccg cggctatggc ttgattttga agccacgtat ccttttgaaa tcatctcagt
     1861 tcggtcaata ttgggataat aactttcctt tgtcaggtta ttttccggct gtgcagccca
     1921 ttgcataaaa cagtttacag cacgcttagg acggtaaccg tcccatagaa gcaatccgta
     1981 cccttgggta gcagccagtt cttttgcctt caaaagcgat tcagccaact cgtatgtccc
     2041 tacaatgcga tttacttcat aaccgtcaac cggttttccg gtgaaattat cccaagtggc
     2101 atatttagcg tcccaacgaa caccgtgtac tatttcatct aaaaaagtaa atcctatttc
     2161 catgcttatc acccctttaa cgctaatacg atcaagcggt caatcagttc gggaagtgca
     2221 atacctgcag cggccatcat acggggataa cgactgtatg acgtgaaacc gggcagagta
     2281 ttgacttcgt tcagtacaat gcggccgtta tcttgtaaaa acatatccac acgggctaga
     2341 cctctacagc cgagcgcttt atatattttt tttgccgttt cctgtatccg tcctcgctcc
     2401 tctgctgaaa ggtctgcggg aacggttata actgcgtttt cagagccttt ttccggctcg
     2461 acttcctgat gaatacgaaa gattccgtac tgcagcctga tttggtccac ctcgccaaca
     2521 actaacgcgg cactgtttcc caataccgca caaccgacct cacagcccga aacagcctgc
     2581 tcaattaaga ttttgctgtc atattgtctt gccgattcaa ttgcgtagtc caattcgtcc
     2641 gcgctattga cttttttcac accgaaggat gagcctgaac gcgccggctt aacaaaaaca
     2701 ggataggtaa acgtagctgc caccggccta tcatctttat taataaccca aaaggcggga
     2761 gtagctatcc cagcattttt cgcaacgatg tatgtcaacg atttgtccat acaaattgct
     2821 gagctttgaa tatcgcagcc tacaaaaggg ataccggaca attcaaacag accttgtatg
     2881 gatccatctt cacctgactt gccatgcaaa gctgaaaatg ctacatcaac atggttgatt
     2941 tcatattcat ggttcttttt aacaagtaat ccgtgcattt ttttatccgg cgagagtaca
     3001 gctgaatagc aattgtcgtt ttcccattcc gcgcaaggtt tttcgcacat tttccataca
     3061 ccagatttcg taattccaat gtataacggc tcgtattttt ctttattaat gttagcggct
     3121 atctctattg cagattttac cgatacgtca tgctcctctg agcaaccccc aaacagtatt
     3181 gcaactttta ttctattcat gctcctgtct cctttcaaaa tccaaacagt ttttaatggt
     3241 tttttcaacg gtatcacgca acgcttgctc ggtataatag gccgtatgcg gtgtgattat
     3301 cacgttaggc attctttgaa gtttaagtaa aaattgatta tcaattggtt tttgggtgca
     3361 atcagagtag aaaaactctt cctctccttc caatacatcc aatgcggcac cgcccagttt
     3421 cccgttttct aatgctttaa ccaactcata ggtatctaca agtggaccgc gcccagtatt
     3481 gataagaaat gctccttgct tcattctctg tatttgttcg tggctgataa tatagtgcgt
     3541 atccgtattg agcggcacat gaagcgtaac gatatcgcta ttttgcagca actcatcaaa
     3601 cggtacatag tttacctcta tacttcggct gcgactataa gccaacactt tacatccaaa
     3661 tcctcgcagc cgctcaataa ccgctttgcc tatctggccc gttcccacca caccaactgt
     3721 catgtcgctg agtaccttgc cacggtcgct gtccaacctg aaatcatgtt tttccacaga
     3781 gcgcacaatc gattttacgt tgcgtactgc cataagaatt agcatcatag tataatcggc
     3841 aacgctatcc ggcgagtacg ccacattgtc gacagtgatg cccattctct tagcagcagt
     3901 tgtatctata tgattgcagc cgatgcttcg ggtagaaata tatttcacac cggctctctt
     3961 cagcgcaaga agaatagagg cggaaatctc tgatttatgt cccacactga tacattgatt
     4021 gaaaggcgcg gatttggcgt tggattccga cacgttggcg ttaattatcg ttgccataac
     4081 gccaaagcga ggcgaaagag catggaatgc atctgcctca tcctgctcac atccataaac
     4141 agtaatgccg atgttattca taattaagac caaccctttc tgtgaaaggc accaaataaa
     4201 acggggatgc caatggtaat cttgtcaaat ctttctctga agaacgaaaa cggctcgttc
     4261 ttacggtatt aagtctaccg tgtaagaacg agccgtttct taatattaaa ttgttaattt
     4321 cctaagaaaa agtaaagata accttgagat tttcctaaaa aattatatac atctcttagg
     4381 acctc
//
LOCUS       DAZKCW010000120         4329 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000120 DAZKCW010000000
VERSION     DAZKCW010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.126"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(374..988)
                     /locus_tag="ACG84Z_002716"
     CDS             complement(374..988)
                     /locus_tag="ACG84Z_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFP9163505.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1594..1971)
                     /locus_tag="ACG84Z_002717"
     CDS             complement(1594..1971)
                     /locus_tag="ACG84Z_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163506.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2271..3152)
                     /gene="galU"
                     /locus_tag="ACG84Z_002718"
     CDS             complement(2271..3152)
                     /gene="galU"
                     /locus_tag="ACG84Z_002718"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFP9163507.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(3195..4214)
                     /locus_tag="ACG84Z_002719"
     CDS             complement(3195..4214)
                     /locus_tag="ACG84Z_002719"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFP9163508.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         1270 a          919 c          673 g         1467 t
ORIGIN      
        1 ttcattgcaa taatgataac aaatgtacta taattacttt gtaaagagtt ttggggaaga
       61 ctctttcatc aacgtgtatt aagagacaag aaagaatcca tatggattct ttcttgtctc
      121 tttttccact actttttatt tttctgacac tacatattct tataactcat ttctcataac
      181 tgtgaaacaa cttataaaaa taacaaactt taaacaaaac aagcttaaaa tcaaagatga
      241 tccatcttaa aataactaaa acaaaaaaag tagtcgttgt taatcctcat taataatcgt
      301 tttctttttt tcaaacgctc catttttatg tggaacatta tttttttaag gaactttgtc
      361 aacatgtgga taactatttt ccacttgtgt cctggactag ctgttttgct gtaaaataca
      421 aaacttgctg cagcaaaaag atcgttgcaa gagaggctgt tccgcagatc gctggatcta
      481 gatttggcaa agtcaagact gcatcatgta aattggcgtg gttgtccaaa accaaatcag
      541 caaattcaaa taatcgcaaa ccactgctat gttgcgattt gatacttcgt gacaaatcaa
      601 atccagtaac aatgattaat ggatgaccat tttctttgat ccactgagct agttcgatga
      661 ttgccgggtt tcttccttca ttcgaaagaa gaagaaaaat gtcttctgat ttgacagaaa
      721 gctgatcaat aattgcctgt cctgcacctt ctagcgtttc atagacacct ccggctggat
      781 tttcaatcaa tatacttggt acaagatccg gggtttgatc ccaaaattca aatgctacac
      841 cacttagtgt gcggctagca tatatctgca atctaccacc ttgattaatt tgtttcgcga
      901 tccaagtgcc agcttgaagc atcagcggct cttctatcct taatttctct tccaattggt
      961 gataatagtc aaaataacat aaactcattt atctctcccg cctagctata cttgacatga
     1021 atagaaacag ctgcctaatc taaggaagta cataaaaaaa cagtagttag acagtaacac
     1081 atgtggtctt tgctgtttca aacacaaaaa aggcattgaa cgaatacgcc caataccttg
     1141 acatagcaaa taaaacaacg tgcagaccat ggaaaatatc tacatagggg tagaattttc
     1201 accctagatt aggtacaata aattaggtcg atgcactgca ttgactatgg caaaatgatc
     1261 ggtcagggtg tatgtgtgtg actggtcatt ccctgattct tagcgccaac taagggtcag
     1321 ggagcctttt tttattcagc tgtttctatc tgaatttatt gtaagtaatc tcttatccaa
     1381 gtgcaagcaa gaaaatacaa aaaaacattg gtatgattta tatatatata aataacataa
     1441 aaaaaggaat ggcttatccc gatacaacaa gcattccttt aaaaaagatt cttttatata
     1501 agtgaaaaaa gcttttttcc accaattaaa taaatctctc atctcaatag tttatccatt
     1561 attttatctt tttttgcgta tacctactaa atattaccgt cttcttctcg ttcttctact
     1621 ttgttcgaga gaatctgtac tagaaaaagt agttgtatgt ctaccttttc tgcctatccg
     1681 agactttctt ttcatatatg ggatataaat gattagatac agtacagcaa aaaataaagc
     1741 aaatacgcaa gcttcccaac tacctaacgc caattcaacc atcaaggtag caaccccaac
     1801 ggatgctgca taccagataa aaatcagaaa cgtttctttt tttctgacca tgcgaaacat
     1861 gataaataga ctaataagca atagtggcaa cacaaatatc caattgcttc cttccatcag
     1921 ccacttgagt atatcaagca gcgactgtgc aacagcgact aattttccca tagtgaacac
     1981 acaccttttt ttataattaa aaaattcgcc tttttattct actatgaatc ttctggcttg
     2041 gctttcattt ctcttatgta atcattttct tttatacaac ttaaaaaaaa attaaaccat
     2101 tagcataata ttttctgaat ctattcacga aagtcttttt ctatctttcg ttttccacga
     2161 ctcaactgat ctagagtcaa aaaactaaaa cgacagttgc gcaaatgacg cacaagctgc
     2221 cgctttaata acaaatagcc tttcattctc agcaggccac ttatttccag ttaactttct
     2281 gttcttagct ttttactcaa ctggataata tatgcactta atgaagtccc aatttccgaa
     2341 tgttgaagtc catattcaat atttgtcttc atatatccta acttatcgcc tacgtcgtat
     2401 ctttttcctt taaactctct cgcatagacc gcctctgtct ggttaagagt ctgaagtgca
     2461 tccgttagct gtatctcgtt tcctgctcct ggttcttgag tttctaatat ctcaaatatt
     2521 ttaggagtca gtagataacg tccgataatg gctaaattac ttggtgcttt tcccatttca
     2581 ggtttttcta caaacccttt tactctgcaa cgaccctttt cgctatctgt tttaggatca
     2641 ataattccgt atttagatgt ttcattttct ggtacacgca tgacggcaac agcggaagct
     2701 tgtgtttctt cataatccat catcaattgt tgagtcaatg ggatatcatc tttcatcaaa
     2761 tcatccccca gcatgacgac aaacggttca tttcctataa atgcttttgc ttgaagcacg
     2821 gcatccccca gtcctcttgg atgagattga cggatgaagt gaagattgac ttgagtcgtt
     2881 tcttcaacta aagcgagtaa ttctgttttt tccttttccc gcaaattgtt ttccaattcg
     2941 atatttgcat caaagtgatc ttcaatgggt cttttttctt ttcccgttac gatcaagatg
     3001 tcttcgattc ccgaatccaa tgcttcttcc acaataaact ggatcgttgg tttatccacg
     3061 attggaagca tttcttttgc catggctttt gttgccggca aaaaacgtgt tcctagccca
     3121 gcggcaggaa tgactgcttt tttgaccttc acttgctgtt cctcctaaac gacgattaac
     3181 tattgatcat ctatttaacg aagagaaaat tcattctcca tttttccgtc acgtaacatg
     3241 atttcttttg ctgctttttt gatatcttct ccattataca aaacattata gattgtttga
     3301 gtaattggca tctcaacacc tagctgttga gctagctcta ctgctgcttt tgtcgttgcc
     3361 acaccctcaa cgaccattcc catgttttct agaacttctt ccagcttatg tccctgtcct
     3421 aacaagttac cggcacgcca attgcgagaa tgaacacttg tacaagtaac gatcaagtcc
     3481 cccacaccac tcaaaccgat aaatgtcaga ggattggcac ccatcgcgac accaagacgg
     3541 ctgatttctg ccaatcctcg agtcatgatt gctgcttttg catcatctcc gaatcctaat
     3601 ccatggatag cgccggcacc aattgcaatg atatttttca gtgctgcacc agtttctacg
     3661 ccaatcacat cattatttgt ataaatcctg aaataatcat tcatgaacag tttttgtaca
     3721 taggctgctg ctttttgatc aatacttgca gctgtaattg ttgtgatatc atgtactgcc
     3781 acttcctcag catggctagg accagataat acaacaattg cctgtctttt ttcttctgga
     3841 atttcttcag ccaaaacttc tgagattcgt ttatgcgtat cttgttctag tcctttactt
     3901 gcatgtataa tgattggctt agtattcatt ttaccaataa gttcctgtgc gactgaacga
     3961 atcgcttttg ttggaacaac aaataaaata gcatctgcgt tatccactgc ttctgccaat
     4021 tctttatatc cgataatcga ttctgggatc gtcaaatcag gtaaaaaatg ctgatttgta
     4081 tgatacttat tgatttcatc aatctgttca ggtacatttc cccaaatacg gacatcatgc
     4141 ccgttttctg ccaatgtttg tgctaaagca gtgccccaag atccaggacc aagaactgcg
     4201 attttttgtt tcatggatat tcctccaaat aaataattga taatttccat tatagtatac
     4261 atttcttaaa gttgggacta atttccattg tttttaagtg tttgtttact tcttttatcg
     4321 tttttactt
//
LOCUS       DAZKCW010000121         4293 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000121 DAZKCW010000000
VERSION     DAZKCW010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.127"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..790
                     /locus_tag="ACG84Z_002720"
     CDS             <1..790
                     /locus_tag="ACG84Z_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFP9163509.1"
                     /translation="CGYSKTEPRHSFGPAIREQYLIHIVLEGEGYYSINDQKYFLKKG
                     QGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYYLKEIGVGKNHLTFKVENLNSFK
                     GLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSASYLNEGIITKKMNPFVRQTIEII
                     RENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISIKEYISEIKISIANDLLSSTEYS
                     IQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRLGLGIINGE"
     gene            887..3136
                     /locus_tag="ACG84Z_002721"
     CDS             887..3136
                     /locus_tag="ACG84Z_002721"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFP9163510.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3139..>4293
                     /locus_tag="ACG84Z_002722"
     CDS             3139..>4293
                     /locus_tag="ACG84Z_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFP9163511.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1501 a          610 c          790 g         1392 t
ORIGIN      
        1 ttgtgggtat tcaaaaacag aacctagaca tagttttgga ccagctattc gagaacaata
       61 cttaatacac atagtgctag aaggtgaagg ctattattca attaatgatc aaaaatattt
      121 tctgaagaaa ggccaaggat ttgttatccc accaggagta tctacttttt atcaagcaga
      181 tgaaaaaaat ccgtggtcat atgtatggtt gggtttaagt ggcaatcttg tagaatacta
      241 tctaaaagaa attggtgttg gaaagaatca tcttaccttt aaagtcgaaa atttaaattc
      301 atttaaagga ttaatttttg aaactttatc gtatgatcag gacaatctag tcagtgaatt
      361 gtccagacaa aaacaagttt ataaattttt agaactcctc ttaaattcag ctagttatct
      421 gaacgaaggg ataattacta aaaagatgaa tccttttgtt cgtcaaacaa ttgaaataat
      481 acgtgagaat gcgtatcaaa aattatctgt taaagatatt gctgtcagtc tatcgataca
      541 cgaaaattat ttatcacgat tgtttaagaa tgatatggga atatcaataa aagagtatat
      601 tagtgaaatc aaaatttcta ttgcaaacga tctgttatca tcaactgaat attcaatcca
      661 gcaaatcagt gacaagatag gattctcaac agtacaatct ttttctaaag cctttaagaa
      721 agcaaatggt gtttcaccgg gagtatatcg aaaacgtaga ttaggtctag gaatcattaa
      781 tggtgaataa actaaacatt tgattttgat aaatattcgt tactttaaac gcttactatt
      841 tatgtgagcg ttttttataa tgcaataaag aaacggagga gagcttatgt ataaggataa
      901 tgaaatgaat attatttatc gatcagaaaa ccaacaattt catttgttta atcaggagat
      961 aagttacatt tttaagatat cggaagatgg taaattattg catttatatt atggtgagaa
     1021 cttaccagat aatgactata gtcatctaat tgagatgcat catcggccta tgacaaccta
     1081 tagaaatgaa aacgatttgc tatattcgtt agagcactta aaacaagaat ttcctgaata
     1141 tggtacaaca gattttagac atcctgctat ttcattacta cagaaaaatg gctctcgctt
     1201 atcagatttt gtctatcaag ggtacgaagt ggaagaagga aaacctaaac tagaaggttt
     1261 acctgctacc tatgttgata ataatgatga aagcaaaaca ttgaaagttt atattttaga
     1321 ttcagttaca aatgttcaag tagaattatt atatacaatt tatagagatt atcctgttat
     1381 tactcgtagc gcgcgagtta tgaataaagg aaaagatatt caaataatcg agaatattag
     1441 cagtttatca ttggatttac ccgatgcaaa ttatgaatgg caacaattat ctggtgcttg
     1501 gggtagagaa agaactatta agtcgcgtac tttacaacaa ggaattcaat caatcgaatc
     1561 tactcgaggt atttcaagcc atcagcataa cccatttgtt actttaaaaa gaaaaaatac
     1621 tgatgaaaat caaggagaag ctattggtgc agcactagtt tactcaggaa acttcttaat
     1681 tcaagcagaa gtagatacat gggatgttac tagactacaa gttggcatca atccatttgg
     1741 atttaattgg aaactcaatc caggagaaat atttacagca ccagaagcga ttctggttta
     1801 ttcaagtaag ggtttaaatg ccatgagtca aacttttcat caactattta gaaaacgctt
     1861 agctcgtggt aagtggcgag aaaaagaccg tcctgtctta attaataatt gggaagcaac
     1921 atattttgat tttgacgaag aaaagttggt aaatattgct aaaaaagcat ttgatgttgg
     1981 tattgaatta tttgtattag atgatggctg gtttggagaa agagaaaacg attgtgcagg
     2041 attaggagat tggcatgtaa atcctaaaag actacctaga ggaatcggca gcctttcaga
     2101 aaaaattcgt agttttggta tgaaatttgg tttatggttt gaacctgaaa tggtgaataa
     2161 ggatagtgag ttatatcgca cacatccgaa ttggattatt tctacaccta atcgaaaacc
     2221 taatcatggt aggaaccaat atgtattaaa ttttgggtta gatgaggttg ttgaaaatat
     2281 tttcgatcaa atgtgtaaaa tcattgatga atcaaactta gattacatta agtgggatat
     2341 gaatcgtcca ttgactgatg tatttgacag tcacttgtca gcagatcaac aaggagaagt
     2401 attccacaga tatgtactag gcgtatatcg cttatatgaa aaacttataa caaaatatcc
     2461 taacatacta tttgagtctt gttcatcagg tggtgggcgc tttgatcctg gaatgcttca
     2521 ctatgcacct caagcttggg ctagtgatga ttcagatgca attgaaaggt taaaaattca
     2581 atatggaact agtatgctgt atcctctttc gtctattggt gctcatgtat caattgttcc
     2641 aaatcatcaa acaaaccgta taacacctat aaaaactaga ggaaatgtag ctttttttgg
     2701 tgcatttgga tatgagcttg acttaaatga attaagtgaa ggcgatttga ggattgtaaa
     2761 agaacaaatt gccttttata aaaaatatag aaccataatt cataatggta ctttttatag
     2821 actattatca ccattcgatg atgataatca aaccgcgtgg atggttgtta gtcatgataa
     2881 gaaaacggct attgttgctc attataaaac attaaatgag gtaaatgctc cttaccgccg
     2941 actgaaatta aaagggttag ataatgacgg actttataat gtaggacaaa atagtttgcg
     3001 atctggaatg gaattgatga gagcaggact agtctgttca gatgcatcta gtggacaaat
     3061 aaatgatcag aatcgacgcc cagaaacatt tgattttgat tccaagattt gggttataac
     3121 acaggaggaa aagtagagat gaataaccaa aaaagcttac ttcaaaaagg agcaatctta
     3181 agtatttcac taatgttaac aagctctcaa gcaattaatg gtgttattcc acaaatgaaa
     3241 cagtctttgg ggatatcaca aagtcaaagt gaacttttag gaactgcacc aagtataact
     3301 gttattttgt ttatcttatt atctagttac tttgccaaaa gaataggaat gaaaaagaca
     3361 ataattttag gtttattatt agctggtata ggaggaatta ttccagtatt tacagctacc
     3421 ttccaaaccg ttcttattag tcgagtaata ttaggtgccg gtttaggagt atataattca
     3481 ttggctgtga catatatcag ctctttatac tctggcaata ctagagcaac gctattaggt
     3541 attagaaatt caatggaagc tttaggtcag acaatcctta tttttcttgc tggagtttta
     3601 gtgaacatta attggacggc ttcgttttta gtctatgcaa ttgcgtttcc tgtagctctc
     3661 ttattcgcgc taaaagttcc tgaaattaga gatgaaaata gtgacatacc tgaaaatcat
     3721 gtaaaagaaa agatgaatcc aatggttttt gccctagttc tatttgcaat cttactcgta
     3781 atgaatagta ttgctatttc tgtacgattt gcatcaattg caactgaaat taaaggggta
     3841 aactttaatg ctagtaacta tttagctcta atgcctatct taggaatact agcaggattt
     3901 atgtttggac caataaataa gtggatagga aaaggaaccc tatacttggg aattatattc
     3961 tttataattt caaatttgtt aattgctgtg tcaaacggta atatgacgtt cctgctaacg
     4021 ggtttatttt tatcaagtat aacaggatca tggtgcttcc catttatctt tagtaactta
     4081 gataaagtca ctacaaagaa tacaattaat tttgctactt cattgatttt tattggctgt
     4141 aatattggta attttatagc tcctattgct atgcaattag cacaatttct aacaagaagt
     4201 acaaatttga ctgctccatt ttttgtattc gcaggaatat ttattgtgat cctatttgta
     4261 acattttttg cgacaaataa aaaaaatact aga
//
LOCUS       DAZKCW010000122         3811 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000122 DAZKCW010000000
VERSION     DAZKCW010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.128"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            261..1304
                     /locus_tag="ACG84Z_002723"
                     /pseudo
     CDS             261..1304
                     /locus_tag="ACG84Z_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
     gene            complement(1509..2828)
                     /locus_tag="ACG84Z_002724"
     CDS             complement(1509..2828)
                     /locus_tag="ACG84Z_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFP9163512.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            2986..3270
                     /locus_tag="ACG84Z_002725"
                     /pseudo
     CDS             2986..3270
                     /locus_tag="ACG84Z_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            3263..3610
                     /locus_tag="ACG84Z_002726"
     CDS             3263..3610
                     /locus_tag="ACG84Z_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163513.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFAELLKWSQI"
     gene            3607..3789
                     /locus_tag="ACG84Z_002727"
     CDS             3607..3789
                     /locus_tag="ACG84Z_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163514.1"
                     /translation="MNIIKKYEFGYITYEQLIEELWGYGQQLINEVGIDCFCFYIESG
                     AGYHKNRYYIFPYPPK"
BASE COUNT         1309 a          592 c          741 g         1169 t
ORIGIN      
        1 taaaacagca tagttctcaa attgtttaaa atgattgtca agttaaaaaa atctgggatc
       61 atataaaata gtatagttct caaatatgat tagaaaccct attaaagagc aatattaagc
      121 caacttactt aaatcgttta attaagaaca gtaatctctt ttagtcagac ttttagtctg
      181 acttttttgt atttccaaaa tttattcttt acaaaaacga acatatgttt gtataattgc
      241 ttgtgaatgg gggaataaaa atgtttgatt acagtagaga accggtgaat gactattttt
      301 taatcgacat gaagtctttc tatgctagcg tggaatgtat tgaacgaaat ttagacccaa
      361 tgactacacc gttaattgtc atgagtagat cggacaacac tggttcaggt ctgactctag
      421 cttcttcacc tactgcaaag aaaaaatatc atattactaa tgttagtaga gctactgatt
      481 taccttatcc attaccaaaa gaacttcata ttgttccacc acgaatgaac ttatatataa
      541 aaaaaaatat ggaagttaat cagattttta gaaagtatgt cgcagatgaa gatttattga
      601 tttattcgat tgatgaatca attttaaaag tgacaaaatc cttaaattta tttactagtt
      661 caggaacaag aagcgagaga agaagagaat tagctaaaat aatcaaagat gagattcaga
      721 aagaaacagg tctaatagca acagtcggaa taggagataa cccattatta gctaaactcg
      781 cactggacaa tgaagcgaag agtagtaaag aatttatagc tgagtggtct tatgagactg
      841 tacctgaaaa aatatggaaa ataaacgaga tgactgactt ttggggcatt ggatcacgca
      901 tgaaaaaaag attgaatcat atgggaatta tgagtataga agatttagca aattggaatc
      961 cctacacaat taaaagtcag ttaggtgtaa tcggacttca gttatatttc cataccaatg
     1021 gaattgatcg tacggatatt gctattccac cagaaccaac caaagaaaag tcttatggga
     1081 attcacaagt tctaccaaaa gattatacga ggagagaaga agtagaacta gtagtcaagg
     1141 agatggcaga gcaagtagcc attcgaatta gacaacacaa ttgcaaaact ggttgtgtac
     1201 gcttagcaat tggtacgtca attttggaag aaaaatcagg tttctcgcac cagatgaaaa
     1261 taccaattac agataatacg aaagaattac aaaattattg tctttcctga ataattcata
     1321 gctttaattc tttggcacat tttattgaaa tatgtatcac taatatccct atcaactgat
     1381 tttgactaaa aagttacttc aaacattcac tgttcaaaaa tattgaggaa taaattttgg
     1441 gtgtaaggca ttttgagcat acttctccct ggataacttc ccagtaaaaa aatcgttaga
     1501 ttgttggatt agatccattg actggctcgc ctcaggcgag caaagaccct gtagaattca
     1561 ttctgataca catgataact agataatttg agatagactc gtctacccgt ttggactaat
     1621 ttcccagcaa ctttcagaaa cttcaatcga atagaatgaa tggtcattcc cttttggact
     1681 tcttcaaagc caatcgttct taagaagttg actaagttgt aagctatcaa gctgagcatc
     1741 attcggacat gattctccaa aaagcgagga ctgtctgttt tgtcaaagta aaagccagct
     1801 ttcgcttctt taatgaagtt ctccattgtg ccacgtttgg catagataga aaagatggta
     1861 tcaggagaaa cattttctga tagattcgtc acgataaatt catgtcgaaa gagtagttcg
     1921 cccgcttcac gtgttgagcg tatacacacg cgacgacttt gtgaccagga ttgtgcttga
     1981 taagtggtcg agaagtactg aacttctcgt tcttcccact tttgattatc gccataaagt
     2041 actgatttct cagctatttg acctagtcta cgattattct tcagtcgaat aacataatga
     2101 ctcttttttg attcacacga atcatacaca ccaggtgtag cgaacccgct gtctccacga
     2161 accaagatgt cagtgtttgg tagagagtga ttatagtgct ctaataaagg tgtgagaaac
     2221 tcctttacgc cttttgatgt atattgattt cctgaacgta gttcagcttt taagaagtca
     2281 ccagtcaatc cgtcaaaagc taccaatgga tggtaaccat aggtttggta gtgtgtatta
     2341 taattcgttt gttcttggtg accaaatgta tctgaatggg tcgaatctaa atcaatgatt
     2401 aattccgtat cattacggat gaggcgtgct ttatcgataa gttcttggtt caaagcttga
     2461 agttcatgga tattctcctc agatagtcga tctaaaaatc gggaaagtga agattgagaa
     2521 gcgagttctt tcctatctaa aacagcttta aacacaggat cttgtctcag gagattagct
     2581 gcagaatcag ctgagtaacc agcaattaat tgcataatga actgctcaag tatggataag
     2641 ttgtcatgag taaaatacgc tcgttcgtct tcaatgtgaa tgtgttgctt agccagttca
     2701 gaaaaaccaa agatgttcat cagctctttc actaggacga gacccgaatc actcgataat
     2761 tgaccacctg tatgagaaat agtgatattt gaattgaatt ttacttggtt tttgtgtaag
     2821 ctagtcatga aaagaactcc tttcttttgg ttggtttagt cactttaacc atagcagaaa
     2881 ggggttcttt tttcatcact taacgggtga agatgaaaaa gtaattgtaa gctgccgtga
     2941 ggcagtttca catggtttta attaaaagta tgaattattc agggtctttt tttattcaat
     3001 aagttttatg aggggcagga agtacgacat ataggagtaa cttatagcag attagtatac
     3061 acagattccc tacaattaga tttatttagt gatccaagaa aaaagattgc tgaagaaaat
     3121 ttggatagga ttattgataa aattagacaa aaatatggat ttacagctat tatacatgct
     3181 tcatctatgt tagaaggtgc aagaagtatt acgagaagca ctttaatagg aggacacgca
     3241 ggaggattag gaggtttgca taatgattga atataacgat agaggacgtt taaaatggtc
     3301 gggattttat ttgtctgatc atactgaaag aatcaatgca gacaatgtac aacgtgctaa
     3361 tcataatttg gcaaaagaac aaatgacgac tgaagagatt gcgaaaatac tgagaactgc
     3421 tgtcataaaa aatagacccg tctgcattca aaaagaggaa cgaaacgctg aaggttacta
     3481 tccagatgat gtagtaggaa aaattattgg atatgacgag cttggtgtat ttgtggaaga
     3541 agaaaaagtt cactatgatg aaattaggaa tgtttctttc gcggaattat taaaatggag
     3601 tcagatatga acattattaa aaaatacgaa ttcggttata ttacgtatga acagctaata
     3661 gaggaattat ggggatatgg tcaacaatta attaatgaag tggggattga ttgcttttgt
     3721 ttctatattg aatccggagc aggataccat aagaacagat actatatatt tccatatcca
     3781 ccaaaatagt ctcttagaga tttttaaatt t
//
LOCUS       DAZKCW010000123         3793 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000123 DAZKCW010000000
VERSION     DAZKCW010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3793
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.129"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(151..537)
                     /locus_tag="ACG84Z_002728"
     CDS             complement(151..537)
                     /locus_tag="ACG84Z_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFP9163515.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(805..954)
                     /locus_tag="ACG84Z_002729"
     CDS             complement(805..954)
                     /locus_tag="ACG84Z_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163516.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            1416..1628
                     /locus_tag="ACG84Z_002730"
     CDS             1416..1628
                     /locus_tag="ACG84Z_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163517.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(1906..3705)
                     /locus_tag="ACG84Z_002731"
     CDS             complement(1906..3705)
                     /locus_tag="ACG84Z_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFP9163518.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         1299 a          675 c          652 g         1167 t
ORIGIN      
        1 aaatcgattg attgccttgc tctttagttt gttttaggac tttaagaaca gtgaggctga
       61 cttcgaaggt taattctgtt tttttgtttt ctagaatcag taagcaaaaa agcactcact
      121 tcgagtgctt ttttgcgata tattcttagc ttaagatagg cctaattttt cttttacaga
      181 tgagggtacc ttatcgctgg taattacttt tttctctatg atccgctttt cgcttgcttt
      241 caactgcaag atcgttcctt cggtgtaagc agaaccattg gcagagtcac cagaagtaat
      301 gacatcgaaa tctaactgtc ttttttcacc gttttcagca taagcatcta cgttgtattt
      361 aaaacctctt ccaattactt ccccattatc tgctttgata tcagtttctg caggcattgg
      421 agctttgact accgcataat aatctttacc tacataagta gactgatagt agtcccaacc
      481 tttccatcct ataaaagcaa tcaatatgat aacgatcaac cctaaaattt ttttcatgaa
      541 agatctcctt ttttattttt attatattaa atattataca gataataacg gaatattatc
      601 atcgaaacag ctaacaaaat tgtcataaaa aacgagatgg ttgatattag aacttgtgtt
      661 tttgtttagg tctagagata aagagagaca atttccaaat atatgtaatg aatacaaaaa
      721 gacgtttgtc gcggattacc gttacaaacg tcttttattg attttccgag atctcatcag
      781 tcgccatttg gaatggttca ctccttatct agattcgttt aatgctcgga ctgcttgttc
      841 gattgtaata ccaaacgcaa cgttattttc gttttgtgca tcaatcgcca taaaacggtt
      901 agaagttgta tcaaaagcta cgcggtattg catatttgtt tttgtaaacg tcataaaatt
      961 catctccttt gtaatgtaat ttagttcttg aaagtttcct ttaaactttc gaacttatac
     1021 caagtttagc atcgtacgtt ttttgatgca attaaaaagc atttatcatt ttccttattt
     1081 attttttctt aaatggttta gctattttct tttaatccga taagtagccc aatcatcaag
     1141 gttacaaata ctattgcttg aatataaatc atatgctcac ctctttataa ataacttagc
     1201 aatataaaga aaaaaacgca cgaacaacat aggaatataa acaaacgttt ttgtcacaac
     1261 gtctaagatc gtgttaaaaa atagttatct aaaaagcaga aagatactca aaataaaaaa
     1321 taaaaaaatg aataaaaacg ttttcaaata caaggtaatt tgttattata aaataaagaa
     1381 aaaacaaaat aaaaataaag aaaagaggga atgaaatggt aaaagcagaa gtaggaagat
     1441 cttatatatg caaaccgatc ggagtatctc atgaactaat cggctgtatt gaacgtacat
     1501 atatcaacac ggctgtcgtg tatgttgaaa gttatgacca acgagactat caacttatca
     1561 atgaaagcaa gtatcgcatg ctcgtaaaat tctgtgatat tagcgcacct actgaattgg
     1621 tttcttaaac agtatttttg agaattcgca agaactccct tataatataa ataaagacag
     1681 aagggagcga gaagatatgc caaaaagaaa aagttcaggg aaaatgggaa ttattcttgc
     1741 agtgatctct gcaattcctg ctattttagc tattgttcgt gcgatgaagg aatcaagaga
     1801 aagttaagca cacattatga gcgtcaaaca aaaaacgcat atacctgcgg tggcaggtta
     1861 tgcgtttttt gttgtataaa gacttttttc attaacgatt tttgattagc cgactcccaa
     1921 aacaaaattt agcagtttat ctgaataagt gatttcttca tctgtttgtt tcacactttc
     1981 atttagtagt cccatctcat cggttatgat accatccaca ccataaaaca tcatgcgact
     2041 catggcatct gaatcgttga ttgtccatac atatacttct tttccgtctt ggtgggcaga
     2101 attaatgaag ttacggttga tcgtactata ttccattgtc agaaaatcag caggcgtcac
     2161 agggggccca acaatattga aaggtaagat gtagcccaca taaaagtttg gttctgcttc
     2221 ttttaaatct gaaacggttt ggtacgtcaa actttgcaaa atatgatggt tctctaagat
     2281 aactttgcgg tatttatgga caaatcgttc gacaaggtca tccgaatctt ttttagaggt
     2341 cttgatctca ataagtaatt tttggtttag cttatgtgct ttttccaaat aagaatcaaa
     2401 agaacaaaca ggggcttgca ctccgttttc agtaactgta agatttgtca attctttcaa
     2461 tgtaagatcc tgtggtgttc catttacccc tgttaagtga cgaagatttg catcatgcat
     2521 cactacgaaa tgaccatctt ttgtttcctg aacatccatc tctacataat caggatgata
     2581 gtctctgctt gttttttcaa gtgcttctaa agtattttgc gccccatttt gggtactcac
     2641 acctctgtga gagacagtca ctggttttgt ctgaacagct gaagtcagat aatccatatt
     2701 gtaaagacag acgccaatac cgaaaaaaac tgcaaaaaga gtcaaaccag tgtttttcag
     2761 cgcagagaaa cgcaagttgg gggcttgtgg gataaaccac ttagggatct caggcaagaa
     2821 gccttcgtca tccatgaaat caacaatgat ataaaaaatc cctacggtag acatcacgat
     2881 attgaataat aaaatccctt gtaaaagcgt catagcaaac acagcgctga tcaatgcata
     2941 gtctgggaaa aattgttcaa ccatactttg tgccaaaata acaacgatat atcctaaaga
     3001 agaaaggagt aaaatcgtac cgccaatcac aataaattgg cccgtgatgg ccaaaagacg
     3061 cgatttggtc aatgaccagc tttcccgaat ggctgctcga aaagaacgat ctcgtagaat
     3121 catttccggt aaagcaaaaa tcagtcgaat cccaatatag ccaaggaaaa tataaacgag
     3181 taaaaaggaa ctgacgatga tccaacgatt agcaaaaata aaatccataa tgaaagcggg
     3241 gatttttatt tttgacagta gatcagaatt aaaacttaat ccgctgatcg gtagaatcaa
     3301 taaaaaataa gcaaggaaaa acaaaaaagt aatgggtctc actttcttca gctgaagtat
     3361 cgtcaagtgt aagagttgct tcaaagagat tggttctttc tttttaataa aaaaaacact
     3421 catcaaaaga aaagtaaatt cgaaataaac taacagtaaa atcgtcatca aaactacgat
     3481 taacgagagt agaaccccag gatgttgaga aaaaattgaa ggaatattgt cataagacaa
     3541 atagtcaatt gcccctcggt gtaaaataaa acgggtcgta ctgctcaata agggtaaaca
     3601 aataaataaa ataaagccat gcatcagcaa gacatcacgg aaataagctt gtgttccttt
     3661 taaaaagtcc caagcattac ctaagctacg tttcaaataa ttcatcctat cacctgctct
     3721 tcacattgta gcgcaaatct aatgaaaaag gaaagggtgc agtgtgtttt gcagaccctt
     3781 tcccagattt aac
//
LOCUS       DAZKCW010000124         3765 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000124 DAZKCW010000000
VERSION     DAZKCW010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.130"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..525
                     /locus_tag="ACG84Z_002732"
     CDS             <1..525
                     /locus_tag="ACG84Z_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163519.1"
                     /translation="LEKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTI
                     SNEINQYREREPEIQPAEVKQEHKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRT
                     LHLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKN
                     EIYYEQQLSQKERV"
     gene            586..2055
                     /locus_tag="ACG84Z_002733"
     CDS             586..2055
                     /locus_tag="ACG84Z_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFP9163520.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVGDDRLDHAVAFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFN
                     LKIGDPKHLKFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRR
                     KQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKAT
                     YEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETIDLKE
                     ACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHEHEF
                     VPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2066..>3765
                     /gene="topB"
                     /locus_tag="ACG84Z_002734"
     CDS             2066..>3765
                     /gene="topB"
                     /locus_tag="ACG84Z_002734"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFP9163521.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     "
BASE COUNT         1392 a          638 c          832 g          903 t
ORIGIN      
        1 ttggagaaag ctattcctta tattgcagca tggacgaaga atggtcagac gttggatgat
       61 aaggaagctg cggaacgtgg gaaaatcatg aatgatgtca gccgtgtcgc aaatgaattc
      121 attcaaacca tttctaatga aatcaatcaa tacagagaaa gagaaccaga gatccaacca
      181 gcagaagtga agcaggagca taaaaatact gtagaaacgg cagaacaaaa gaatattgtt
      241 cctgttggtt cactttggat cgacaagaaa gacgggaaag taatggaaga agatacgggt
      301 cgaacgttac atttgaagga tgcggcgttt attgaagatc cacagcataa tcaagtaatt
      361 ttaaaaggaa aaagttatgg aaaagagatc caaacggcgt taccttcaga agaatttgcg
      421 ctaggaaatt cattccgatt ttcacttgag acagtgtcag aagtggcaaa acgaaaaaat
      481 gaaatctatt atgaacaaca attgtcacaa aaagaacgtg tataaaacaa gtaaaaaaga
      541 ctatctgaaa aacggatagt cttttttctt ttgggaggtt ttaaaatgac cgagaaaaaa
      601 atgagtctta ttgatcgatg taaacagatc gatatagtgg attttgctcg aaacaatgga
      661 atggctgtag tcaataaagg acgagactat cgcttagaag accatgattc atttgttttt
      721 gatcgaagaa aacaacgttt ttattggaac agtcaaaata ttagtggcga cattattgaa
      781 ttagctaaac tttttttcat agacaaagag atccaagacc ctaagcaaca atttaaagca
      841 gccactgatt ttattctaaa gaatgaagac aaaacagaac gagtggaaaa tcttcatttt
      901 gagacagaaa agtacaaaga tcaccccgtt gattatcaac cactcacaga aaaaggaagg
      961 aattatctga aggaagaacg aaaactacca gagtggctga ttgattatgc agaaaaagaa
     1021 gggttgattg ctgaactaaa gccgaaacat gaacggcaaa attttttagt tggagacgac
     1081 cgtttagatc atgcggttgc ttttttatgg aaagatccac agacaggaga gacagtaggg
     1141 gcaagttatc aaggaacgat cgtcgatttt aatcgtttcg gtaaacgggg aacgtataaa
     1201 cacattgaca agaatcctac gccaaatcac ggatttaatt taaaaatagg cgatccgaag
     1261 catttaaaat tctttgaaag tagtattgat ctgttaagtt acgctgcatt gaatcgggag
     1321 aaactacaag atgcctggtt agtttcgatg gacgggttaa aacatcatgt aatcagtcat
     1381 tacgttgaag agtcgatttc tgaattaaga cgaaaacaaa catttcctca atcgattgaa
     1441 atatgtgtgg acaatgatcg tgcaggacat attttttatg aaaaagaaca gatgaaggga
     1501 atcgttgatc cttttaccaa taagaaaatc cgttgtgagc gaggaattcc aaatgattgg
     1561 caagtaccta aagaatacaa agctacttat gaagcagtcg caaaagaaat gagtgttgaa
     1621 cctgaagcaa ttatggccat acacaaaact gaaactaatt tacagctgac aaatcaattg
     1681 gtgtctgctc atgatgttca atctacgttt ggaaagatgt tggcgaaggg cgaaccagta
     1741 gaaacaattg atttgaaaga agcatgtacc acggtcgcga aggaactgaa agtatgtgaa
     1801 cgcgcagatg gaacatacaa ctttgatcgt ttttatagta gaaaagccaa cataaaagac
     1861 gttaatgcag gaatccttct ttcctataaa gcagaacaat actacaaagg ctataaaaag
     1921 catgaacatg aatttgtacc tgaagtgaaa aaggattgga atgatcaatt gaagcatgag
     1981 atccagcaac aagaaatcag aaagcaaaaa cgtgcgatgt tgtttcaaca aggcagacaa
     2041 caagaaaggg agtgaagtcg tcactatgaa aaccgtcatt ttagcagaaa aaccgtcaca
     2101 agcgaaggct tatgccgata gcttttctaa agctacccga aaagatgggt attttgagat
     2161 ccaagatcga ttgtttacag gagaaactgt gatcacgtat ggttttggtc atttagtcga
     2221 gttagattcg cccgatatgt acgatgaaaa atggaaacaa tgggcattag aacatttgcc
     2281 tattttcccc aatcaatacc actatcatgt tcctaaagat aagaaaaagc agtttagtgt
     2341 cgtcaaacga cagctgcagt cagctgatac gattgtgatc gcgactgata gcgatcgtga
     2401 aggggagctg attgcctggt caatcattca acaagcaggc gccaatcaag gaaaaacctt
     2461 taaaagactt tggatcaact ccttagaaaa agaagccatt tatcagggat tccaacagtt
     2521 acgagacgca gaagagacct atccaaaatt tgaagaagta caagcacgtc agatcgccga
     2581 ttggttaatt gggatgaacg gtagcccact gtatagttta ctcttgcagc aaaaaggcat
     2641 accaggaagt ttttctttag gtagagtcca aaccccaaca ctctatatga tttatcaatt
     2701 gcaggaaaag attagaaact tccaaaaaga accatatttt gaaggaaaag cccaagtaat
     2761 cgctcaaaat ggcgcatttg atgcgaagct tgatccaaat gaaacccaag cgacacaaga
     2821 agcatttgaa gcctatttaa aagaaaaagg tgttcaatta ggaaaacagc caggtacgat
     2881 ccttcaagtc gaaacagaga aaaaaagtgc ggctagccca cgtctttttt ctttatcgag
     2941 ccttcagtct aaaatgaatc aactcatgaa agctagtgcc aaagatactt tggaagccat
     3001 gcaagggttg tatgaaggaa aatatctaag ctatccgcga acggataccc cttatattac
     3061 ggaaggggaa tatgcgtatc tgttggatca cttagacgaa tacaagcatt ttttaaaagc
     3121 cgaagcgatt ccgactccta ttcatacacc gaatagtcgg tatgtgaata ataagaaagt
     3181 ccaggaacat tacgcgatca ttcctacaaa aacggttatg acagcagcgg cttttgaaca
     3241 actaagtcca ctgcagcagg ctatttatga acaagtgtta aaaacaacgg tggccatgtt
     3301 tgcggaaaag tatacctatg aagaaacaac gatcttgacg caagttcagc agcttcagtt
     3361 aaaggcaatc gaaaaggtgc cgctagatct aggttggaag aagttatttg gaaaagagag
     3421 cgacggaaaa gagaaggaag aagagccgct acttcctaaa gtgacaaaag gagaaatggt
     3481 gacggtggat ctacaagttc ttgaaaaaga aaccaagcca ccacaacctt ataccgaagg
     3541 tacgttgatc actgcaatga aaacagctgg gaaaaccgtg gatagtgaag aagcgcaatc
     3601 catattgaaa gaagtggaag gaatcggtac agaagcgaca cgggcgaata ttattgaaac
     3661 cttgaaacaa aaggaatata tcaaggtaga gaaaaataag ctcgtggtga cgaataaagg
     3721 gattttgctt tgccaagccg tggaaaaaga gccgctgctt acgag
//
LOCUS       DAZKCW010000125         3756 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000125 DAZKCW010000000
VERSION     DAZKCW010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3756
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.131"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..525
                     /locus_tag="ACG84Z_002735"
     CDS             <1..525
                     /locus_tag="ACG84Z_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFP9163522.1"
                     /translation="SEKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTI
                     SNEINQYREREPEIQPAEVKQEHKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRT
                     LHLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKN
                     EIYYEQQLSQKERV"
     gene            586..2046
                     /locus_tag="ACG84Z_002736"
     CDS             586..2046
                     /locus_tag="ACG84Z_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFP9163523.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2057..>3756
                     /gene="topB"
                     /locus_tag="ACG84Z_002737"
     CDS             2057..>3756
                     /gene="topB"
                     /locus_tag="ACG84Z_002737"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFP9163524.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAESIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     "
BASE COUNT         1382 a          649 c          825 g          900 t
ORIGIN      
        1 tcggagaaag ctattcctta tattgcagca tggacgaaga atggtcagac gttggatgat
       61 aaggaagcgg cggaacgtgg gaaaatcatg aatgatgtca gccgtgtcgc aaatgaattc
      121 attcaaacca tttctaatga aatcaatcaa tacagagaaa gagaaccaga gatccaacca
      181 gcagaagtga agcaggagca taaaaatact gtagaaacgg cagagaataa gaatattgtg
      241 cccgttggtt cactttggat cgacaagaaa gacgggaaag taatggaaga agatacgggt
      301 cgaacgttac atttgaagga tgcggcgttt attgaagatc cgcagcataa tcaagtgatt
      361 ttaaaaggaa aaagttatgg aaaagagatt caaacggcgt taccttcaga agaatttgcg
      421 ctaggaaatc cattccgatt ttcacttgaa acagtgtcag aagtggccaa acgaaaaaat
      481 gaaatctatt atgaacaaca attgtcacaa aaagaacgcg tataaaacaa gtaaaaaaga
      541 ctatctgaaa aacggatagt cttttttctt ttgggaggtt tgaaaatgac cgaaaaaaaa
      601 atgagtctta ttgatcgatg taaacagatc gatatagtgg attttgctcg aaacaatgga
      661 atggctgtag tcaataaagg acgagactat cgcttagaag accatgattc atttgttttt
      721 gatcgaagaa aacaacgttt ttattggaac agtcaaaata ttagtggcga cattattgaa
      781 ttagctaaac tttttttcat agacaaagag atccaagact ctaagcaaca atttaaagca
      841 gccactgatt ttattctaaa gaatgaagac aaaacagaac gagtggaaaa tcttcatttt
      901 gaaacagaaa agtacaaaga tcaccccgtt gattatcaac cactcacaga aaaaggaagg
      961 aattatctga aggaagaacg aaaactacca gagtggctga ttgattatgc agaaaaagaa
     1021 gggttgattg ccgaactaaa gccaaaatat gaacggcaaa atttcttagt tcgagacgat
     1081 cgtttagatc atgcggtcgc ctttttatgg aaagatccac agacaaaaga gacagtaggg
     1141 gcgagttatc aaggaacgtt cattgattat gaacgttttg gtgagagagg cacatataag
     1201 catatagata aaaattcgac agcgaatcat ggctttaacc taaagatcgg tgaccctaag
     1261 cagttaaaat tttttgagag tagtattgat ttacttagct atgctgcact gaatcgtgat
     1321 cagttaaacg atacgtggtt agtctctatg gaagggttaa aacaccatgt gatcagtcat
     1381 tattttggtg aggcagtatc tgaattgaga aagaaacaag cctttcctca atccatcgag
     1441 atttgtgtgg ataatgaccg tgcaggacat attttctacg aaaaagaaca attaatgggc
     1501 gcagtcgatc catttacgaa tcagaaagta cgttgtgaac gaggaatcgc taatgattgg
     1561 caagtgccaa aagaatacaa aatcatttat gaagaagtcg caaaagaaga aaaggtcaca
     1621 ccagaagcta ttatggccat acacaagaca gaaaacaatc tgcaattaac gaaccaactg
     1681 gtttccgctc acaaagtaaa tgcgtttttt ggccagcagc tttctgttaa cgattcaata
     1741 gaagccatta atttgaaaga tatttgtaga gaagtcgcaa aagaattaaa agtttgtgaa
     1801 cgcgtggatg gtacgtacga ttttgatcgt ttttatcaag aaaaagggga tattaatgcg
     1861 cagattcttt tctcttataa agcagaacaa tactacaaag gctataaaaa tcatgaacat
     1921 gaatttatac ctgaagtaaa aaaggactgg aacgatcaat tgaagcatga gatccagcaa
     1981 caagaaatca gaaagcaaaa acgtgccatg ttgtttcaac aaggcagaca acaagaaagg
     2041 gagtgaaatc gtcatgatga aaaccgttat tttagcagaa aagccgtcac aagcgaaagc
     2101 ttatgccgat agcttctcta aagccactcg aaaagacggg tattttgaaa tccaagatcg
     2161 attgtttcct ggtgaaactg tgatcacgta tggttttggt catttagtcg aattagattc
     2221 gcccgatatg tacgatgaaa attggaaaca atggtcatta gaacatttgc ctattttccc
     2281 tacacattat cactatcatg ttcctaaaga taagaaaaag caattcaagg tggtgaaaca
     2341 gcaacttcaa tcggccgaca ccattattat tgcgacagat agcgatcgtg aaggggaact
     2401 gatcgcttgg acgatcattc aacaagtagg cgccgatcaa ggaaaaacct ttaaaagact
     2461 ttggatcaac tccttagaaa aagaagccat ttatcaggga ttccagcagt tacgagacgc
     2521 aaaagagacc tatccaaaat ttgaagaagc acaagcacgt cagatcgccg attggttaat
     2581 tgggatgaac ggtagcccac tgtatagttt actcttgcag caaaaaggca taccaggaag
     2641 cttttcctta ggcagagtcc aaaccccaac gctttacatg atttatcaat tgcaggaaaa
     2701 gattagaaat ttcaagaaag aaccttattt tgaaggaaaa tccgaagtaa tcgctcaaaa
     2761 tggcgcattt gatgcgaagc ttgatccgaa tgaaacccaa gcgacgcaag aagcatttga
     2821 agattattta aaagaaaagg gggttcaatt gggaaaacag ccaggcatga ttcgccaagt
     2881 tgaaaccgag aaaaaaagcg cggcaagtcc acgtcttttt tctctatcca gccttcagtc
     2941 taaaatgaat cagctcatga aagctagtgc caaagacact ttggaagcca tgcaaggctt
     3001 gtatgaaggg aaatatctaa gctatccacg aacagacacc ccttatatta cggaagggga
     3061 gtatgcgtat ttgttggatc atttagatga atacaagcat tttttaaagg ccgaatcaat
     3121 cccaacccct attcatacgc cgaatagtcg gtatgtgaat aacaagaaag tccaggaaca
     3181 ttacgcgatc attcctacaa aaacggttat gacagcagcg gcttttgaac aactaagtcc
     3241 actgcagcag gccatttatg aacaagtgtt aaaaacaacg gtggccatgt ttgcggaaaa
     3301 atatacctat gaagaaacaa cgatcttgac gcaagtccag cagcttcagt taaaggcaat
     3361 cggaaaagta ccgatagatc taggttggaa gaagttattt ggcaaagaga acgacggaaa
     3421 agagaaggaa gaagagccgc tacttcctaa agtgacaaaa ggagaaatgg tgacggtaga
     3481 tctacaagtc cttgaaaaag aaaccaagcc accacagcct tataccgaag gtacgttgat
     3541 cacggcgatg aaaacagctg ggaaaaccgt tgatagtgaa gaagcgcaat ccatattgaa
     3601 agaagtggaa ggaatcggta cagaagcgac acgggcgaat attattgaaa ccttgaaaca
     3661 aaaggaatat atcaaggtag agaaaaataa gctcgtggtg acgaataaag ggattttgct
     3721 ttgccaagcc gtggaaaaag agccgctgct tacgag
//
LOCUS       DAZKCW010000126         3702 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000126 DAZKCW010000000
VERSION     DAZKCW010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.132"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(133..297)
                     /locus_tag="ACG84Z_002738"
     CDS             complement(133..297)
                     /locus_tag="ACG84Z_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163525.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            592..1920
                     /locus_tag="ACG84Z_002739"
     CDS             592..1920
                     /locus_tag="ACG84Z_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFP9163526.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2122..2955
                     /locus_tag="ACG84Z_002740"
     CDS             2122..2955
                     /locus_tag="ACG84Z_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFP9163527.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2971..>3702
                     /locus_tag="ACG84Z_002741"
     CDS             2971..>3702
                     /locus_tag="ACG84Z_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFP9163528.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKN"
BASE COUNT         1234 a          583 c          769 g         1116 t
ORIGIN      
        1 aaagcttatg caaagaaaaa gaaatccaat cacttgggtt tctttttctt ttattattat
       61 gatgaatcaa gctttctgtt tttgtcacgt atgttgtaat ctttacgaaa gagtagagtt
      121 ggctactcat aatcaaccat acttcccatc atcgctaaat acgaaataaa tcagcattcc
      181 tacaccaatc aaagcacaag ctgcaccaag aaaagggatg acattcccaa agttatctgt
      241 attcataagt atgccaccac ccacaaacaa aaagccgcca gcaatcaggt ttttcatttt
      301 attcatctcc tttcttacgt tatagtattt ccttctttca atgagtattt tgaaagctat
      361 cttattgtat gatgttcttc taggcctctt ctttattata caggccattt tcgttatctc
      421 atagaaatat tcctttttat ctgaaaacta ttgtataccg tatgacattt ttcttcatga
      481 agttgtaagt atattctcat tcaaatgaaa atttcatcat agaagagatt gtatttctaa
      541 attcttaaga gtaaaatacg aagtataact tggatttgga aggatgattg gatgaaagct
      601 attacgcctg atatgacaac aaaatttaac aaacagtttc aagcaaatat caaacagcag
      661 gcattgcagc gggcagttgt gaagaacgga attactgctt ctgctgaaaa tgtttcagca
      721 catgtggaga atacaccggt attttctata gatttggcta cggggaaagt ggctaatcaa
      781 atgcaatcgg ggcgttgctg gatgtttgct gcactgaaca cattccgtca taagatgctg
      841 aatcaattcc atttaaaaga gtttgaatta tcacaaaatt acactttttt ctgggataaa
      901 tatgaaaagg caaattattt ctatgaaaac atcattgcaa caggaaaaga ggcaatcgat
      961 agccggaaag tagctttctt actcgctact cctcaacaag atggcggcca atgggatatg
     1021 atcgtttcat tattccaaaa atatggcgtt gtgcctaaat cggtgatgcc ggaaagtgcg
     1081 aatagttcaa attctcgaga tttgaataac tacttgaaca aattactgcg taaagatgca
     1141 gtagtgttac ggaaaatggt tgctcaagga gaaacattag acgctattga agaaaagaaa
     1201 gaagaaatgc tagaaagcat ttataacttc ttagctatct cattaggaac acctccaaaa
     1261 gaattcgatt ttgagtaccg cgatgaagaa aagaactatc atcttgaccg aggactgaca
     1321 ccacaaattt tttatgataa atacatcggt gtaaaattag atgattatgt tagcgtgatc
     1381 aatgcaccaa caaaagacaa accattcaat cgttcttata cagtagagat gctaggaaat
     1441 gtcgttggcg ggaaagaagt caaatatctg aatgttgata tggaaacttt caaaaaatta
     1501 gcgattgctc agcttgaaga aggagaatct gtttggtttg gttgtgatgt aggtcaatct
     1561 tctactagaa ctagtggcat catggcctta gatgcttatt caatggatga tctatttgat
     1621 acggatttta caatgactaa agctgaacgt ttagattttg gagaaagtct gatgacccat
     1681 gcgatggtat tgaccggtgt tgacttagta gacgggcaat caacaaaatg gaaagtcgaa
     1741 aatagctggg gcgaaaaagt tggaaagaat ggcttctttg ttatgagtga tgcctggatg
     1801 gacgaatata cgtaccaaat cgttgtaaga aaagatttat tgacgaaaga gcaattaaat
     1861 gcgttcaatg aagaaccaat tgttctatct ccgtgggatc caatgggtgc tttagcatag
     1921 acgagtattt caatgaagag tatgtagtaa agataaaaag agctggctta agccagctct
     1981 ttttatcttt aaagtccatt ccctgttttt tatggtccct gtgctataat tctaaataaa
     2041 ggataaggat tggaaataat ccttttatca ttaaaaatat gatgacgaag tagaataaaa
     2101 ttgggagtag gggggaaagt catggatatc caaactgttt tatctgatct gaaattaaat
     2161 ggtaaagtga ttccagttgt tggtggcgat gttaatcaga cctatcgtat aaaaaccgaa
     2221 catcgtgctt attttttaaa aatccatccg aatgtaaaaa aaggattttt tgaagcagaa
     2281 gtagacggat taaaagaact gtcagcattc gtacgtgtac cggatacgta tatgctaggt
     2341 gaaacaagtg aaggcgctta tttgttaatg gaatggatcg agccgggaaa aggggatcaa
     2401 cgagatcttg ctgcagcttt agctaatctc catcagcaaa cagcgccaca atttggtttt
     2461 cgtaaagata actatttggg tacacttgtt cagaaaaatt cttttgaaga agattggtgg
     2521 acttttttct ttaaagatcg gcttgaatcc cagatttctt tggcagaaga aacgaatcga
     2581 tggaatgtac agcgtcaaga aaagtatctg cgatttaaag aacgtgtatt gaaatcggtt
     2641 gaaccaaaaa agatcactcc acgcctcttg cacggagacc tgtggagtgg taatgtgttc
     2701 tttgaccagc aagggcatcc agtttttgtc gacccagctg tttcttatgg gaatcgggaa
     2761 caagatattg caatgagcca gttattcggt ggtttccgac cggaattttt agatgcttat
     2821 caaactatat ttccattaga aaagggatgg aaagaccgac tgccgattta ccagttatat
     2881 tatcttttgg cacatttgaa tatgtttgga gaaagttacg gttcccaagt agatcaatta
     2941 ctagaaaatt tttaagagga gggcgtgttt ttggcaaaaa aatataccaa aaagcatgaa
     3001 gtttcatatt atgagtgtga catcaaccaa acgatgacat ttccttcgat gttaggagta
     3061 gttatcaaaa cgtctgaaga tcaaagcgac cagttgggaa gaggcagtga attcgtcaat
     3121 agctttggac ttacttgggt catcacgaat tattccatgg agattaatcg tctccctaga
     3181 gtcggtgaag taatctcagt aacgactcaa gccatggagt acaataagtt tttctgttat
     3241 cggaacttct ggatccatga tgaagatggg aaagaattag tcaaaataga atctgttttc
     3301 gtattgatgg attttgtgaa tcgaaaaatg agcagtgtta atgaagagat cattgctcct
     3361 tttgagagtg agaagatcaa gaaaatcaag cgtcaggaaa aaattgaaaa gattgattcg
     3421 ggcttcatgt tgccatatcg tgttcgtttt tatgatatcg atagtaatca gcatgttaat
     3481 aatgcgatgt attttaattg gatcattgac gtattaggat atgacttttt gactacgcat
     3541 gttccagaaa aagtaattat tcgatttgat aaagaagtag agtacgggaa tgagatcgaa
     3601 agccattttg aacaaatccc tatcgaaaat ggtgtcaaaa caaaacatga aatccgaatg
     3661 caagaacagc tgtattgtga agcaaatatt atatggaaaa at
//
LOCUS       DAZKCW010000127         3665 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000127 DAZKCW010000000
VERSION     DAZKCW010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.133"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1087
                     /locus_tag="ACG84Z_002742"
     CDS             <1..1087
                     /locus_tag="ACG84Z_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9163529.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="ACG84Z_002743"
     CDS             complement(1305..2447)
                     /locus_tag="ACG84Z_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9163530.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="ACG84Z_002744"
     CDS             complement(2452..2637)
                     /locus_tag="ACG84Z_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFP9163531.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="ACG84Z_002745"
     CDS             complement(2991..3236)
                     /locus_tag="ACG84Z_002745"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163532.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="ACG84Z_002746"
     CDS             complement(3230..3631)
                     /locus_tag="ACG84Z_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFP9163533.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
BASE COUNT         1196 a          664 c          562 g         1243 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaat
//
LOCUS       DAZKCW010000128         3488 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000128 DAZKCW010000000
VERSION     DAZKCW010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.134"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2232)
                     /locus_tag="ACG84Z_002747"
     CDS             complement(<1..2232)
                     /locus_tag="ACG84Z_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFP9163534.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="ACG84Z_002748"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="ACG84Z_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          983 a          770 c          549 g         1186 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtattgcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagttttact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaaac attcgttaca tatttgtgaa tttttccaaa
     3421 aaataacatt tttataaaac aacgaaaaat aaatcactac cagtcaactt ctataatatt
     3481 accaaata
//
LOCUS       DAZKCW010000129         3326 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000129 DAZKCW010000000
VERSION     DAZKCW010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.135"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..134
                     /locus_tag="ACG84Z_002749"
     CDS             <1..134
                     /locus_tag="ACG84Z_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFP9163535.1"
                     /translation="NQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLT"
     gene            complement(190..2553)
                     /locus_tag="ACG84Z_002750"
     CDS             complement(190..2553)
                     /locus_tag="ACG84Z_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
                     /protein_id="HFP9163536.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2718..3222
                     /locus_tag="ACG84Z_002751"
                     /pseudo
     CDS             2718..3222
                     /locus_tag="ACG84Z_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          912 a          693 c          596 g         1125 t
ORIGIN      
        1 tcaaccaagt caatcaagga ttcatctcat ccgttgcgtc caaaagaaac catatcccta
       61 gaaaatcact aaattaccaa acaccattag aagttttttt gagttacgta aatggaaagt
      121 tttgtctcac ttaatttgac aaataataca atgtaaaaaa ttctgttttg cgggatcgat
      181 tttatcattt tattggtcaa gatttttcca tttccaatcc aatacttctg gcagatcaat
      241 accattttca cgaatatagt tttgatgttc ttgtaatttc tgatccattt tttccgcaaa
      301 atcttctgct tgacttcctt tgatttttaa agctgcgtct tttgccaaat gataacgatc
      361 aagttcattt actacacgca tgtcaaatgg tgtcgtgata tctccatttt ctttgtagcc
      421 atgaatcatt aaatgatggt tatgacgatc aaagaaaatc gtgcggacca atgtttcata
      481 accgtggaaa gcaaataaga tcggtttgtc ttttgtaaaa tattgatcaa attcttcatc
      541 gctcaaccca cgcggatctt gacttggatg acgtaatttc aataaatcta cgacattgat
      601 gaaccgaatt tttagttttg ggaattcttc cagcagcaaa gttacagctg ctaatgcttc
      661 taagttagat tccgttcctg cagcagcaat gaccaattca ggttcctcct cttttgctgt
      721 cgaagcccaa tcaatgattt tcaagccttc attcactaag acggctgctt cttctgctga
      781 gtaaaattga gcacgcggat gtttggaaga gatgatcaaa ttgatttttt ctgacgagcg
      841 gaatgcttta tccatgactg cgagcaatgt atttgcatcc gcaggcagat attcacggat
      901 gaactccgcc ttcttttctg ccaaatgtgt caatattcct ggatcttggt ggctatatcc
      961 attgtgatct tgctggaaga ctgttgagct tgcaatgaga ttcagcgaag gataatcttt
     1021 tcgccaagaa aggtcatgtg atttccgtat ccatttgaag tgctgagtca acatagagtc
     1081 aaccactcgc aagaatgatt cgtaacttgc aaaaaaacca tgccgtccag tcagaacgta
     1141 cccttctaag aacccttcat cttggtgttc cgataattga ctgtcgatga cgcgaccaga
     1201 tggcgaaagc cattcatcat tttctggttc gattttttcc atccattggc gatttgtcgt
     1261 tttgaaaact tgattcaatc ggtttgattt tgtttcatct ggtccaaata tacggaaatt
     1321 ttctggattt ttctcaatga tctcgcgaac gaatttacca agttcggtca tatcttctgc
     1381 tttaacggag cctggttttt caaattgcaa agtatatttt ttccaatctg gcataataag
     1441 cggtcttgga tcgattccac cattggtgat aggatttttt gccattcttt ggtcaccagt
     1501 aggcgcaatt tctctgattt cttctaaaat acgtccttgt gcatcaaata atttttctgg
     1561 ttcataggat ttcagccaac ggagtaaagc atctgcatga tccatatgtt cttgatctac
     1621 aggaatcggt acttggtgtg ctcggaaggt tccttcaatt ggttccccgt cccattcttt
     1681 tggaccggtc catccttttg gtgtgcgtac gatcaatact ggccattttg gcatcacgac
     1741 atctgttgct gtcttcaggc gagcttcttt ttggatggat ttgattttct cgattgcttg
     1801 atccattttt tcagccataa caggatttaa tttttctgga tcatttcctt caataaagaa
     1861 aggctcccag ccaagtccgt taaagtaatt tgctaattct ccatctgatt tacgtgccaa
     1921 gatcgttggg ttggctattt ttgcaccatt taaatgaagg atcggtaaaa cagctccatc
     1981 tatcactgga ttgataaaga catttgagaa ccagcttcca gctaaaggac cggtttctgc
     2041 ttcaccatca ccaatcacga cagcagagat tacttcagga ttgtctaata cagctccgac
     2101 tgcatgtgaa agagagtatc caagctctcc gccttcatgg atagaacctg gtgtttctgg
     2161 tgctgcatga gaagcaatgc ctccaggaaa tgaaaatcgc ttgaataatt tttgcattcc
     2221 tgtctcatct tccgttactt ctggatagat ctctgtgtaa cttccatcta aataagcatt
     2281 cgataccatg acttgtccgc cgtgtcctgg cccttcgata taaaacatgt tcaaatcata
     2341 tttattgatg actcggttca aatggacata aataaaattt tggccaggaa tcgttcccca
     2401 atgaccgatt ggatgttttt tgacatcttc tggtttcagt gtacgtctca gtaaggggtt
     2461 atctttaaga taaagttgcc caacagaaag ataattagca gcacgccacc aagccgtcat
     2521 tttatcaaag tattctttac tagaataatc catacataac actccttttc attattactc
     2581 ttattctagc gcagatactc ccaattgaaa cctaataagc acttctgttc atttgtttgg
     2641 attttatatc tagccaaatg aacaggtata aaaaaccacg aaatttttcc tttcgctgac
     2701 gttttttaca ttgatccaaa aaacttgtcg ttatcacaat ggctgttccg cagttcattt
     2761 cgctcctcat catgcataat ttgctgaatg acgctaggcc agttaacaca ttgttggaaa
     2821 actggggctg gatcgagcaa ttcctttcct gattgatccg ttttatgtaa aagtctctgt
     2881 tatctttgtc aatatgtgaa ttggtatccc agctactatg ctaatttcta cagggattat
     2941 ccaaaatttg gatcgtgacc aaatcgaagc ggcgtaatcg gaaatatcaa taacttcaac
     3001 gtgatttttc ttttaactgt caacggaccg acaaactcaa acttttatgg tgcaggttcc
     3061 actgatcttc tagttacttg gctatacctg actgtcacta aaatagatta caatctagct
     3121 tccgttatcg gtatcttgat ctttatctat atgcaaaaat ttatatacta tagaaaaaag
     3181 aaagtcgaat tttttacttt tctttttctc ttttttggtt agctgacacg ctaccagact
     3241 aaagtcatgg aactcttagg taatacgtct taatgaaaac aaaaaaatcc cgcaacccct
     3301 gatttcacag gatttgcggg attttt
//
LOCUS       DAZKCW010000130         3313 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000130 DAZKCW010000000
VERSION     DAZKCW010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.136"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..153
                     /locus_tag="ACG84Z_002752"
     CDS             <1..153
                     /locus_tag="ACG84Z_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase DegT"
                     /protein_id="HFP9163537.1"
                     /translation="QPVFKNYDYIGDDVAETLFDLGVCLPSDTKMTDEDLKYVVSTIK
                     RVINDA"
     gene            143..763
                     /locus_tag="ACG84Z_002753"
     CDS             143..763
                     /locus_tag="ACG84Z_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFP9163538.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            959..2059
                     /locus_tag="ACG84Z_002754"
     CDS             959..2059
                     /locus_tag="ACG84Z_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFP9163539.1"
                     /translation="MAKYYNKKILIMANNDDGLYRFRGMLIKNLVDQGNEVIVSLPKG
                     KNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNYCNILKKIKPDMVIAYTIKPNIYG
                     GLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFLYRLAAKKSKVIFFENFENMKTFQ
                     TLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVHFLFIGRIMKEKGVDELFEAMKNL
                     YSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYHGYQSDIRPFVERAHCFVLPSWHE
                     GMANTNLESAASGRPIITSDIPGCKEAVIESKSGYLCERKNSCSLYNSMNKFLKLSYE
                     QRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            2066..2461
                     /locus_tag="ACG84Z_002755"
     CDS             2066..2461
                     /locus_tag="ACG84Z_002755"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9163540.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            2458..>3313
                     /locus_tag="ACG84Z_002756"
     CDS             2458..>3313
                     /locus_tag="ACG84Z_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFP9163541.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKIGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKNKIINLIYPKLIEDEHGE
                     YFSPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDI"
BASE COUNT         1300 a          375 c          618 g         1020 t
ORIGIN      
        1 caacctgttt ttaaaaatta tgattatatt ggcgatgatg tagcagaaac tttatttgac
       61 ttaggagtat gtttaccatc agatacaaag atgacagatg aagatttaaa atatgtagta
      121 tctacgatta aaagagtgat caatgatgcg taaaaaaact ttctatcagc tttttgggaa
      181 aagaatttta gatatcctat tgtcaggaat tgctctcatc gttttatcgc cgataatctt
      241 aattgtaggt tttttagtaa gaattaaact tggttctcca attatcttca aacaagaacg
      301 accaggaaaa agtgaaaaaa ttttttccat gtataaattt cgtacaatga ctgacgaaag
      361 agaccacaat ggagaatatt tacctgatga aattcgacta actaaatttg ggaaaatgct
      421 tagagcaaca agtctggatg agctacccga actttggaat attttgaaag gtgatatgtc
      481 gatcgtagga cctcgtccat tattagtgga gtatttgcca ctatatagtg agaagcaacg
      541 gaaaagacac aacgtaagac caggattaac tggactggct caggtcaatg gaagaaatgc
      601 tattagttgg gaagaaaagt ttgatttaga tgtttattat gttgataaaa ttagtttctt
      661 taatgatctt attattataa ttcagacatg taaaaaagta atcaagaaag agaatattaa
      721 tacaatcaat aacaatatcc cagaaaaatt taaagggagt taaatacagc agcttaatgc
      781 aagttttgtg acttgcatta tatttaggta taaatcaaag cgagtatatt agaattatat
      841 aacatatgtt aaaaaaacgt atagctaata aaagtatgat tttaaaaatt tgtgtagagt
      901 tttaaatata ctgtttcaat acgagaaaat tataaaaaag tataaggaaa agagagttat
      961 ggcaaagtat tataataaaa aaattcttat aatggcaaac aacgatgatg gtctttaccg
     1021 ttttcgagga atgctcataa aaaacttagt agatcaaggt aatgaagtta ttgtatctct
     1081 tccaaagggc aagaatattc ctaaattaat tgaacttgga tgtcaaatta ttgaaactcc
     1141 aatagataga agaggaatta atccaaaaac tgactttaaa ctatttttta actattgtaa
     1201 tattttgaaa aaaataaagc cagatatggt cattgcttat actatcaaac caaatatata
     1261 cggtggattg gcatgtcggt taagaaaggt ttcttatgca ttaaatataa ccggattagg
     1321 aacggcattt caaaaaaagg gggttttgaa aagtctcatt gtatttttgt atagattagc
     1381 agctaaaaaa tctaaggtca tatttttcga aaattttgaa aatatgaaaa catttcagac
     1441 tttacaaatt gctaaacaaa gtaaatacaa gctattaaac ggtgcaggag tagatgtaga
     1501 acactttagt tatttagaat atcctaaaga tgagcaagtt cattttttat ttattggaag
     1561 aattatgaaa gagaaaggtg tagatgaact ttttgaagca atgaaaaact tatatagtga
     1621 agagaaaaat tgtgtacttg atgtccttgg gtattttgaa gaagattacg gcataaaaat
     1681 tgaaaaatac gaaaaagagg gatggttaaa atatcatgga tatcaatctg atattcgtcc
     1741 ctttgtagaa agagcacatt gctttgtttt gcctagttgg cacgaaggaa tggcaaatac
     1801 taaccttgaa tcagcagcat cagggagacc aattattaca agtgatatcc cagggtgtaa
     1861 agaagcagtt attgaatcga agtctggtta tttatgtgaa agaaaaaata gttgtagtct
     1921 ctataattcg atgaataaat ttctaaaatt atcatatgag cagcgcatta acatgggaaa
     1981 aatggggaga aattatatga ttaaaaaatt taataagaag aaagttgtcg atgaaacaat
     2041 taaatcatta tttagttaaa aagatatgtt ttgcaaagta tgtgatagaa aagagggatt
     2101 ctgtggcttc agaatagata tcaaagaatt ggcaaaagtt tctgatattt ttttatttac
     2161 tacattacaa gaaggaatgc caagatctat gatggaagct atggcaagtg gattgccatg
     2221 tatagcaagt aaaatccgag gtaatgtaga ccttttagtg gaaggaaaag gtggatatct
     2281 tgttccagct aaagatgcag aattagtagc agagtgtttg agagaactaa tcaataataa
     2341 atctcttaga aagtatatgg gaaatgagaa cctttccaga attaaagaat tcgaggttag
     2401 tatcgtaaaa aaaagaatca aagaaatata tgaagaagtt ataggtgaga gtgtaaaatg
     2461 aaaaatccaa tgttttcaat aatagtacct atctattgcg ttgaaaaata tttgaaagat
     2521 tgcttagatt caataagaaa tcagacattt aaaaattttg aagcaatact agttgatgac
     2581 ggtagtcctg acgaatgccc agaaatatgt gactattatt cccaaataga tggacgttta
     2641 aaagtaattc ataagaaaaa tggtggaata atagatgcac ggaaaatagg agtcactagt
     2701 gctatgggag agtatatagt ttttctagat ggtgatgatt ggcttgcaaa tacttattta
     2761 gaaaaatatg cggaagtaat tactaagtac aatccagata taatatgtag tgggtatttt
     2821 gcatcacgtt ccaacaaaat tagaaaaaga gaattgtctt gctcgtttgg atattatgac
     2881 aaaaataaaa ttataaattt gatttatcct aaattaattg aggatgaaca tggagaatat
     2941 tttagtccac aattatgggc aaaagctttt agaactactc tgtacaagga gcaacaacaa
     3001 gtatctgggc aagttagtgt tggtgaagat catgcatgta caaaaccatg tatttaccat
     3061 gcaaattcga tatatatgat ggaaaaatgt ttatattatt acagaataaa cgaaaattct
     3121 ataacaaaaa aaccacaacc atattattgg gaaggaccaa aggctattgg agagcatttt
     3181 gaaaagcaga ttgatatgaa taagtatgat tttcaagatc aagtatatag aaatgttaca
     3241 cacaatttat ttaatgttgc tgtttcacaa tttaataaac aggacaaata tttaaatata
     3301 aaaaaagata tta
//
LOCUS       DAZKCW010000131         3303 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000131 DAZKCW010000000
VERSION     DAZKCW010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.137"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..254)
                     /locus_tag="ACG84Z_002757"
     CDS             complement(<1..254)
                     /locus_tag="ACG84Z_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008177227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9163542.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
     gene            complement(244..1443)
                     /locus_tag="ACG84Z_002758"
     CDS             complement(244..1443)
                     /locus_tag="ACG84Z_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFP9163543.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDDVYSLFFYNRFMKTNA
                     RSDSYDV"
     gene            complement(1573..2949)
                     /locus_tag="ACG84Z_002759"
     CDS             complement(1573..2949)
                     /locus_tag="ACG84Z_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9163544.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2949..>3303)
                     /locus_tag="ACG84Z_002760"
     CDS             complement(2949..>3303)
                     /locus_tag="ACG84Z_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFP9163545.1"
                     /translation="RLVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALV
                     SDAPIILADEPTGNLDSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELS
                     GKKLKKVNKMNLEVE"
BASE COUNT         1013 a          633 c          475 g         1182 t
ORIGIN      
        1 gtatcgactt ccttaatggt ttgtcgcatg gaacggatac cgaataaata ctgaataaac
       61 accaatttga tcagaatcac tggatcgata cttgggcgac ctaaatcgga gtaagtggct
      121 tcgacgattg gataaataaa ttcaaaatca agcgcggcat caatctttcg aacgagatga
      181 tcttgaggaa ctagatcatc aatcgtaagc atcgcaaatt gatttctacc attcgtattg
      241 tttttagaca tcatagctat cactccttgc attcgttttc ataaatctat tataaaagaa
      301 aagactgtag acatcatcca taaaatggac tttgtctaca gtctgcgcat tctcattaga
      361 gaacactccc ttttttgtga cttttctgaa gctagagtga atactttcaa ctgcattagt
      421 agtgtacatg atttttctaa tggcgctgcc ataatcaaag agttgttcaa catgagaaaa
      481 gtttcgtttg catacatcta ctgcaccaga ataatgagac caccgatttt gaaaactgtc
      541 gaaggcagcg tgtgcagcgt ttaaagaaga agcactgtag aattttttca tgtctcgaca
      601 gacttcctta taatccttac ttgggaggta tcgtaacgca tttcgaacaa gatgaacaat
      661 acagcgctgc acaatgacag aaggaaaaat tgcttttgcg ccttctttga gaccggaaac
      721 accgtccatc gaaatgaaaa aaacatcttc tacaccacgt actttcagtt catcaaatac
      781 ttgcatccag cgatttttag attctgtttg attgagccat aggcctaaaa tctccttgtt
      841 tcctttaaga tcatagccaa gaatggtgta cacagcatat tctttagctt catagttttc
      901 gcgtaaagtg acgtacatac aatcaacgaa tagaaatgca taacacttgg ctaatggccg
      961 agcttgccat tcttccaatt caggaaggac ggcatccgtg atatcagaaa tcatttcgtg
     1021 ggaaatatca aagccgtaaa tatcttcaac ggttgcggcg atatcgcatt gactcattcc
     1081 tcgtgcatac atggaaagaa ccttaccttc gatgtcggag acatctcgtt ttctattagg
     1141 aatcaactca ggttcaaaag aagcctcccg gtctctggga acatcaatgt ttactttacc
     1201 aaagctcgtt ttaagcgtct tattgccata accgtttcgt cgattgtcat gtttctttgg
     1261 ctctttagaa tgggcgtcat accctaaatg gttattcaat tctccttgaa gcattttttc
     1321 aaataaggga ccaaacacat cttttaaaac atcttgcata tcctctacag attcgggttg
     1381 ataagtattc aaaatggatt cagctaactt ctcagcatca ggatttcttt tctttctagc
     1441 catcgtgtaa tcacctcttg atcttatttt agaaaaataa aaaccgtgaa gcaaccaccc
     1501 gcctaggatt gatggttact tacacggttt atattacact ctcatttttg gtgctaaaaa
     1561 gcaccgaaaa ttttaattat tgtcaattaa taattctttt ggattccttc ttaatatatt
     1621 gaatgaagaa ataatcaatg atacaagaag tactaaactc ataaatataa ctacataaat
     1681 catgaattta ggtaatacat tgatatctaa acttgataat gtcttgttaa atccttcagc
     1741 ttctgcccca ccacctaatt ggctagatgc agattgttta gctatttgtt tagctatatc
     1801 accagtaacc ttattcaata tattattccc aagcttgtca gctgtatatt gagctaagaa
     1861 ataggaacca acgaatgcgg ggattgatat aaataccatc tcaattagga attgaccaaa
     1921 aatttctaat tttgatatac ctaatgatag taatactgct atttctttct ttctagcatt
     1981 catccataag aataataata atgaaactac aactcctgca aatattaatg agccaaaaaa
     2041 taatttattt gaaattgagt aaatacctga tatagattgt tgtaatgcag ggtaatttga
     2101 tgaactttta atcaaattat attctctcca atttatatct aatttcccaa gatcttttat
     2161 tacactatca agattcttat caccttttac aaagaatgtt gcatcttggt atacagctgt
     2221 atcttcggta ttaccataaa ctttagcagc tgtatgaata tcagtgatta atgtattttc
     2281 gtatagttct tgtgctgcac ttactccacc gctattatgc ccatcgaata gacctttaat
     2341 ttctacttct actgtttcat ctgcaccttt ctcattatca gcatcaaata aattagattt
     2401 tatttttatc ttatctccaa ctttaaggtt atttttttca gctaaatctt tatgcattaa
     2461 gattttattt ttatcttcat tttctaaatg ctttccttct actaatttat atgcttctga
     2521 tacaaatttt gtttcttttg ttgagtcgtt aaccccagtt aacataactg ttcttttaaa
     2581 attctttgct ctttcaggtg attgattcgc aagagtctct tgagtttcaa taatatcata
     2641 atcaactaaa tctgcaacac tgtttattct ttttacatag gagtctatac tatctgtttg
     2701 agatatcttt ttaatatctt caccttttac atttccccca cctctaggtg ttcctggatt
     2761 tacttgtcta tttatctcca tagaaaaact atttgttata ttagcaaatg tttcttttga
     2821 agctctgtcc gtagcatctt taatagataa actaatgaga cttaaagttg acatagataa
     2881 aataactaat atgataatta atgattttaa actttttcta gttacataag caaatgcatt
     2941 ttttatcatt attcaacctc caaattcatt ttatttactt ttttcaactt tttaccactt
     3001 agttctaaaa tgatatccgc agaatctgct acttccttac tatgtgttac aactattaca
     3061 catttatttc tatctttagc taatgtcttt aatatattaa ttatttctcc agcagtaaca
     3121 ctgtctagat taccagtagg ctcatcagct agtattattg gagcatctga taccaatgct
     3181 ctagcaatag ctactctttg ttgctgtcca ccagataatt tcataacatt tctttttatt
     3241 tgttttttat ctaaacctag ttcaaacaag atactttcat ctgctgattt atttactaat
     3301 cta
//
LOCUS       DAZKCW010000132         3109 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000132 DAZKCW010000000
VERSION     DAZKCW010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.138"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..243
                     /locus_tag="ACG84Z_002761"
     CDS             <1..243
                     /locus_tag="ACG84Z_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /protein_id="HFP9163546.1"
                     /translation="CTSEACDFKLWTTIAKKKLTATQLKEIIQNSRTSQPVKGLKGQK
                     GSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            259..408
                     /locus_tag="ACG84Z_002762"
     CDS             259..408
                     /locus_tag="ACG84Z_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163547.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            482..1075
                     /locus_tag="ACG84Z_002763"
     CDS             482..1075
                     /locus_tag="ACG84Z_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFP9163548.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            1091..1990
                     /locus_tag="ACG84Z_002764"
     CDS             1091..1990
                     /locus_tag="ACG84Z_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFP9163549.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            1993..2478
                     /gene="ssb"
                     /locus_tag="ACG84Z_002765"
     CDS             1993..2478
                     /gene="ssb"
                     /locus_tag="ACG84Z_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFP9163550.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            2844..3104
                     /locus_tag="ACG84Z_002766"
     CDS             2844..3104
                     /locus_tag="ACG84Z_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163551.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
BASE COUNT         1150 a          510 c          602 g          847 t
ORIGIN      
        1 tgtacgtctg aagcctgtga tttcaaacta tggacaacga ttgccaaaaa gaaacttaca
       61 gcgacacagc tgaaagagat cattcaaaat agccgaacaa gccaaccagt gaaagggtta
      121 aaaggtcaga agggttcgtt tgaagcaacg attgttttaa aagaagactt cactacaggc
      181 tttgaatttt ctgaaaagaa aaaaacgaac ttcaagaaaa gaacacgacg cactacaaaa
      241 taatggaggg ttaatcttat gcgtaataca acacacaaac aacaagaaat cgaaaatcaa
      301 aaagccaaaa ttcgttcaga acaggaaaaa atgcgtgcca gcaaacgaag actgcagcaa
      361 ttgaagaacc agcagcggat tcaaaaagaa atcgaattag atcgataaat tcctttcttg
      421 ttaatataaa actaacatgt tatagttgtg ttagttttat attaacttta ggggaagagt
      481 aatgaaagac aaaatccaat gtatttttga taaacataat ggcaacctat ccttgaagga
      541 tgctagaagt gaaggattat cgcctatgac gttagatcga ttagccgaaa aggataaaat
      601 agaaaaggta gcaccaggtt tctatacctt aaaggatgcg ttcgtggatg aattgtatct
      661 cgctcagagt atctattcca gagggatttt ttctcatgag actgcgctcg atctttttca
      721 agtaggaaca tatatcccta aaaagatcaa tatgatgttt cctaaaggat acaatgtatc
      781 aaaggagaaa ttagatcagt atgccattca accgcattac actaataaag aaaattttga
      841 cctgggagtc acagaaacag aaagctttta cggcaataaa attttagtct atgatttaga
      901 gcgaacgtta tgtgacatgt ggaatccaag atacaaagca agcgtagagg taaaacaaga
      961 agcattaaaa gaatatatga caagtaccag tagaaataca aataagctaa gaagatacat
     1021 ggatatttta aaatcaccaa aagaaatgac tttgtatatg ttgccacttt attgagagga
     1081 gtaaagatga atgacaccga cacaatttaa agagaaaaca agaaatttcg cagcagagaa
     1141 acatttaaac ccacaaattg tccaaagata ttatatgatg gaaaaattat tagaatgtat
     1201 tgttgaatcg ccttatcatg atgattttgt attaaaaggg ggatttctga ttggatcaaa
     1261 atacgggtta gaaaaccgtt caaccgttga tattgatacg acttatcgaa attcgaaact
     1321 aacaaaagaa aagttagaaa ctgttttttc tgaattaaca gctaatccta caaaagatgg
     1381 aattcgtttt gaattaaagg gattaacaga gacgagggaa gccgattatt atccaggttt
     1441 tcaagcaaag tttattgctt atcttgaaaa tgcacgtgta ccttttaaat tagatattac
     1501 ttcaggtgat tctattattc cagcagcatt gatgtatgaa cacaaattaa tgtttgaaga
     1561 taaaacgatt catattccag cttatcctac ggaacaaatt ctagctgaaa aattacatgc
     1621 cacgtttagt tttggaaaag ataattcgcg catgaaagat ttttatgacc tgtatatgat
     1681 tccgaaatta gaacgtatcg atgagaaaaa tttgtataag agtgttcaag gaacattcaa
     1741 ggaaagaaat aatcaatcgg tgtttaagca tttgtatgat caggaaatgc ctcaattggt
     1801 gaaagatgag ggcttgagag aaaagtggaa aagataccaa caagaaaact attttgccaa
     1861 agacatttct ttcgaatcta cactaacttc cgttgattcc ctgatgcaat caattgtaga
     1921 gcaagagaag gcagaacgaa aacaaaattt taagagatca caacaaatga atcaagaaat
     1981 ggagagataa agatgatcaa taatgtaact ttagtagggc gattaactaa agatccagat
     2041 ttacgttata ccgcaagtgg cacagcagtg gcgacttttt ccctagccgt taatcgtaat
     2101 ttcacgaatc aaaacggcaa tcgagaagct gattttatca attgcgtgat ttggcgcaaa
     2161 ccagcagaaa cgatggcgac attagctaaa aaaggcagct tgatcggcgt tgtcggacga
     2221 attcaaacac ggacttatga caaccagcaa ggacaacgtg tgtatgtgac agaagttgtg
     2281 gccgataact tccaactatt agaaagtaaa gcagcgacag aaagccgtat gcacgctgat
     2341 caatcgtcca gcagtccaag ccctaccacc tttgaacaac gggatacagc gacgcctaac
     2401 aacaatggat tgaacgcttc acagaatcca tttggtggac aatcaatcga tattagcgat
     2461 gatgatctac cgttctaagt agcattttct attggttgca tttgctacgg tttatgttat
     2521 aatttagaca acaaaaagaa ttttcaatct ataaccaaaa accactagct ggcgggctag
     2581 tggctttctt ttacgtttct attataagaa ttaacgggta ggcttactgt ctttcttggc
     2641 aaatttacaa tcaagccatt tgcagatata gtgcgcggct acttctgcca tgattgcaaa
     2701 aacaaaatca aaaagaattt tcaaacctat aacctcctcc ccttgccaga ttaggccggg
     2761 gtagcagaca gcaagactat tatagcataa ttgaaatatc caaatgattg gatttttgct
     2821 ataattttag cgaggtgatt gtgatgaaca aatatgttgg tttgcttgat aaaatccgag
     2881 taataaaaac gcaaccgtta ttggttcgct ttactttaca aacgattcat gaatcgatta
     2941 attgtgtagt tgcagatatt gaaattatcg ataaattgct aattatggat gatggaaaat
     3001 acaatattgc cgtcacaggt cacttcaata aacgaaatca gctagttatt gctagcatgt
     3061 atgttagaaa tcccgatcat tttacgcgat cgatgggcat ataaataaa
//
LOCUS       DAZKCW010000133         3065 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000133 DAZKCW010000000
VERSION     DAZKCW010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.139"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            739..>3065
                     /gene="esp"
                     /locus_tag="ACG84Z_002767"
     CDS             739..>3065
                     /gene="esp"
                     /locus_tag="ACG84Z_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HFP9163552.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         1123 a          457 c          597 g          888 t
ORIGIN      
        1 aaaaattgga tcagttaatt gaaagagaaa gctgggaaga ttattacgtg ggtctaactt
       61 tttcagaaaa gttaaacaac tacaagttaa tagattataa gtatttgagt gaaagcaatt
      121 aattattcat gtagagtact agacacttta aatatggaca attcaattat aaagaaaaag
      181 aatcaataat ttaatgaggc tgtgacaaat gtcatttttt gtttcgctaa aaacgagtga
      241 aaaaatgttg ataactccaa tcattcgttt aagattctag gaatcattca gaaatgctgt
      301 gaaaccgata ctttataatt ataaagaagg tgatttcaaa ttccgaagaa ggaatttgaa
      361 gtcacctttt tacttatgtc acagtctcat tcagtaatgc gggataaggc tccttattcc
      421 gttatttgaa tactctgaag tttaatctaa gaaagggtaa tattttgaaa acatgcttca
      481 tcgcatagaa atgaacttaa tttcagaaag aatacataca tatcttttta tatgttttca
      541 gctgctgaat ggttaaaaag cacaaatatc cgaaaaaaac atgaagaaat gtactttttt
      601 tgttgtaatg ttcatgaaat tctctaagta aattagttaa cataaggtta gtaagattcc
      661 tattctgtga ataatacgta tcagatttat cttttattct tactaggaaa gtaattatta
      721 agggagttga tttgaataat ggttagcaag aataataaga gagtatttct agaaaaaaca
      781 aagaaacgag tattgaagta cagtatcaaa aaattaagtg ttggggttgc atctgttttg
      841 attggtgttg gtcttgtctt gggaacaact gaactagtta aagcacaaga tgaaatttct
      901 ccaagcagcc cacttgaaac agcgataagc tccgtacaag taggtgacaa agtagcttcg
      961 gggaatactt ttcaggagaa tcctggttat acgaaaaatt ataacttttc ggatttacaa
     1021 tttagtcctc aagaactaac tggagacaca ctaaaaggca atacaattgg atttgaagtt
     1081 tacggaaaac ataatattgc agcatcaact aaaaactggg aaatccgtct tcaattagat
     1141 gaacgattag ctaaatatgt agaaaaaatt caggtcgatc caaagaaagg aattggatct
     1201 tctagacgga cctttgtaag aattaatgat tcgctgggta gacctacaaa tatttggaag
     1261 gtcaattata ttcgtgcaag tgatggatta tttgctgggg cagaaacaac cgatacgcaa
     1321 accgctccta atggggtaat tacgtttgaa aagagcctag atgaaatttt taaagagata
     1381 ggcatagaca atctcaagac cgatcgttta atgtatcgaa tctacttggt aagtcatcaa
     1441 gacgatgata aaattgtacc gggtattgat agtacgggct actttttaac agattcagat
     1501 gatttctata atagcttaga tgtatctgaa aataatcctg accagtttaa acatggatca
     1561 gtaagtgcaa aatatgagaa acctaatact caaacaaaag atggttcagg atccacaggt
     1621 gctaatggag ctataatctt agatcataag ttaacgaaaa attataattt ctcatattca
     1681 tcttccgcaa agggcacgcc ttggtatgct aattacaaaa ttgatgaacg attagttcca
     1741 tatgtagcgg gtatacagat gcacatggtt caggctgaca aagtaacata tgatgtttcg
     1801 tttgaatccg gaacaaaagt agctgattta gcaatcgagc gacgggaagg tcatgaaaat
     1861 tatggcatag gttcaataac taataatgat ttaactaaac ttatcgattt tgctaatgca
     1921 agtccacgtc cagtcgttat tcgatatgtt ttacaattga ctaagccatt agatgaaatc
     1981 ttagaagata tgaaagcaac agcacaagtt gaagaaaata aaccatttgg tgaagatttc
     2041 atctttgatt cttggttgtc ggatacgaat aaaaaattaa tccagaacac ttatggaaca
     2101 ggttattatt atttgcaaga tattgatggt gatggaaacc ctgacgataa agaagagagc
     2161 ggagacacga atccatatat cgggaaacct gaattagaag aagtatatga tgttgacaca
     2221 acagttaagg ggaaagtatt catccacgag ttagcgggaa caggtcacaa agcccaactt
     2281 gttgataaag aaggtactgt attagcagaa aaaactatcg ctccaaatga aaaagatggg
     2341 gctccaattt cagatactgt agaatttgaa tttacgggtg tagattcaag taaattaatc
     2401 gcgaaagatg aattaaaaat ccaaatcgtt tctccaggtt ttgataaacc agaagaaggt
     2461 tcaaccgtta ttaaggaatc accaaaagcg gttgataaac aaaccgtggt agttggattt
     2521 aaaccagatg ctaaagaatc aattcggaat aataaaaact tacctgaaga tgcagagtat
     2581 tcatggaaaa cagagcctga tacttctaac gttactgata gtacgaaagg tattgtaact
     2641 gttaagatcg gaaatcgaac tttcgacgtg gatgtagagt ttgctgtaaa agcttctcaa
     2701 gctatggaaa atgatgcaac atacgtacct ataacaacaa ctccagaaac gacagttcaa
     2761 agtggaaaac ctacatttga taaaccagat gttcctttag ctaaagatgc cttttcaatt
     2821 tcagatgtct ataataagta cttcggtaat gcaagtgttg atgcaaacac tggtattgtt
     2881 acattcactc cagctaaagg tgtaggagaa tcggagccga ttactggaac aattcctatt
     2941 aaaattgttt accaagatgg ttctgtaggc acgaccgatt tagcagtaac tgtaagtaaa
     3001 gatatttatg aaaatccagg agaaaacatt cctgcaggct accacaaagt aaccttcacc
     3061 gcagg
//
LOCUS       DAZKCW010000134         3015 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000134 DAZKCW010000000
VERSION     DAZKCW010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3015
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.140"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(280..642)
                     /locus_tag="ACG84Z_002768"
     CDS             complement(280..642)
                     /locus_tag="ACG84Z_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163553.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(716..1096)
                     /locus_tag="ACG84Z_002769"
     CDS             complement(716..1096)
                     /locus_tag="ACG84Z_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFP9163554.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1178..2353
                     /locus_tag="ACG84Z_002770"
     CDS             1178..2353
                     /locus_tag="ACG84Z_002770"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFP9163555.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2429..3013)
                     /locus_tag="ACG84Z_002771"
     CDS             complement(2429..3013)
                     /locus_tag="ACG84Z_002771"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFP9163556.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          941 a          577 c          498 g          999 t
ORIGIN      
        1 aattttttag aaatgtgata taacatccac ttcagaatca acgctgttaa atttatcatg
       61 tatttcttcc ttggtcaact ataaattaag cattactttg tgaaatgatt tttcgatcaa
      121 ttattattat tcgttataca accgttttca acatattttg aaaataaaat gcactaaaaa
      181 actatcttta gcagaacatt tcattgtatt ttttggacca aacaataaaa aaagaagttt
      241 gaaaaaaatt caaacttctt tgttcgctta atctgtattt tagaagaaag gcactccctc
      301 tacttcgtaa gttccaagaa cagagcgcat ttgacctggt tcttcccaaa tatatccttc
      361 gcctaattct tctctttgat tcttttgttc agtttcaaag acaaacaacg gaacattttc
      421 ctctttaata tgtgtatttg tcaattccat caaactaatc ttgctaacat cgatatgaac
      481 tatttctttt aagaaattaa gtatattcgc taaaccagtc tttccttcag aaagttccgc
      541 taacgcaaat tccaacttgt catcaattga atggaccaaa aattttttag taccatcctc
      601 caaatgcaac ataattgtac cagcaactct tttgcttgcc aaaatttcca cctcgatcaa
      661 cttgttctat ggcttacata aaaattctag cacattttca gaaaaaatac actttttatt
      721 tcttattttc tttccgttct agttcagata atgcttcttc tatccaaata ggtaactgct
      781 ccgcaatagt ggtaaatccg atcttacgat ttttattcgt gaaatacctt tttctgcgat
      841 atggaacagc tggatttgtt ttttctaacg ttcttaaaga taaactgatt tttttggaat
      901 attcatcaat gtcgatgatc tgaactgtta ctggctgtcc gacttttaac aatgaatgga
      961 tatttttcgt ataaccggat tgtacttctg aaacatgaat aagtccttgc gtctcgttat
     1021 caagagaaac gaatgcgcca taaggctgta tccctgtcac ttttccttca attatttgtc
     1081 caattttata agtcatctac ttccctctct tcgcatttat cattatactg taaatagctc
     1141 aaaaaaagaa gcgacgaaaa tgactggagg tcttaagatg atcgaatttg ataaacagat
     1201 ttcaagaaaa gatacagaaa gtgtaaaatg ggacgcaatt gctgagacat atcaaatgga
     1261 tgacttactt cctttgtggg tagcagatat ggacttcttg tctcccggtg gggtagctaa
     1321 agcgtttagt gaatacatca aacatggaat ctttggttat gccactctgt ctgataaact
     1381 atatcaggct atcattcatt gggaacgcca acaccatgct gtggagttga cgaaagaaaa
     1441 tatcgttttt acaagtggtg tgttaaccag tttagctgca gcagtacaaa cttttacaaa
     1501 accaggcgat tctattttga ttcatgaccc agtttatcct ccattttcct ctattataga
     1561 aacaaatcaa cgtcacatcg ttcgaagctc tttgctagaa aaaaataatc atttcatcat
     1621 ggacttgtct gacatggaga aaaaaatcga agaaaacaat gtaaaagcaa tgattttatg
     1681 caatcctcac aatcctggag ggcgtgtttg gagcaaagaa gaattgaaac agttaagcga
     1741 attgtgttta aaacatcaag tgattctgtt tagtgacgag atccatcaag atttaacttt
     1801 attcgatcat acatttactt ccatgctaac gattgatcct aatttagatg atctactagt
     1861 tgcttttact tccgcaacca agactttcaa tctagctgca atcaaaaatt caatggtatt
     1921 tatcaaaaat ccagagatga aagctgattt tgaaaaacat ttagtgatga accaacagca
     1981 cgaaatcaac acttttggac tgattggaac ccaagcggct tatgagacgg gtggagaatg
     2041 gttaagccaa ctgattcctt atctagaaaa aaatgttcaa acagttaatc agttttttga
     2101 acagtatctt ccgaaagtga gaataatgaa ccctgaagga acttacttaa tgtggttaga
     2161 ttttaccgcc tatatttcag acgaccaaga attggagaac actcttgttc ggaaaggaaa
     2221 agtcgtatta aatcctggca tcacgtttgg tccttccggt catgggcata tgcgcttgaa
     2281 tattgcttgt ccagaagaaa ctttactgga aggacttaat cgaatcaagt atgctttaga
     2341 gacaatcgat taaatattta ttcaaaataa aaggacgaga ccttactagg tttcgtcctt
     2401 tttcataatt actccgtacc ataccaaact attctgaaat ttcaattgtt tcaatcacta
     2461 catcatgtac aggtcggtct tgtggaccac gttgtacatt tgcgatttca tctactgtgt
     2521 ccatcccttc tagtacatgt ccaaagactg tatgtcggaa atctagccaa ggagttccgc
     2581 cacctttata cgcttcaatg atttctgatg ggaatccagc accttctagt tgtccaagca
     2641 tattagctgg cacatttgtg ttatttacaa taaagaattg gcttccgttt gtgtttggac
     2701 ctgaatttgc catagataaa gctccgcgaa ggttgaacag ttcacgactg aattcatctt
     2761 caaaactttc gccataaata ctttcgccac ccattcctgt tccagttgga tcgccgcctt
     2821 ggatcatgaa atcaggaata acgcggtgaa aaatcacgcc atcataataa ccttttttgg
     2881 aaagttcaat gaaattttga accgtcttcg gtgctagttc agggaataat tgaacagtaa
     2941 tgtcaccacg gtttgttttg ataacagctt ttggtccttt ttcacttttt aaatctagtt
     3001 gtgggaatgc catat
//
LOCUS       DAZKCW010000135         2999 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000135 DAZKCW010000000
VERSION     DAZKCW010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.141"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            155..1051
                     /locus_tag="ACG84Z_002772"
     CDS             155..1051
                     /locus_tag="ACG84Z_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFP9163557.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIVHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLERIIQLENEKE"
     gene            1143..1358
                     /locus_tag="ACG84Z_002773"
     CDS             1143..1358
                     /locus_tag="ACG84Z_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFP9163558.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDQALEEYIRKYLPDKL"
     gene            1376..1648
                     /locus_tag="ACG84Z_002774"
     CDS             1376..1648
                     /locus_tag="ACG84Z_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFP9163559.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILTKEKVA"
     gene            1650..2513
                     /locus_tag="ACG84Z_002775"
     CDS             1650..2513
                     /locus_tag="ACG84Z_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFP9163560.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAISEETQGNVVIIDNDTFKQQHPNFDELVKLYEKDVVKYVTPYSNRMTEAI
                     ISRLRDKGYNLVIEGTGRTTDVPIQTATMLQAKDYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQPPTP
                     PIPKTPKLPGI"
BASE COUNT         1182 a          479 c          520 g          818 t
ORIGIN      
        1 gataaataga ggtctttcca ctactatcta aatggaaaga cctctatttt tcatatagga
       61 gctacttttg ggtcagccct atatattaat cacaaatcac ttatcacaaa tcacaagtga
      121 ttaatcacaa atcacttgtg atttgtgatt cttaatgata caatattact atacaaaaaa
      181 agaatggggc gtagttatgg agaaggaaaa actaaaaata cttgaagaat taagacgtat
      241 tttaaacaat aaaaatgaag caattattat cttgaataat tactttaaag gtggtgttgg
      301 aaagtccaaa ttatcgacta tgtttgctta cttgacagac aaattgaatt taaaagtttt
      361 aatgatcgat aaggacttac aggcaacatt gacaaaagac ttagcaaaaa cttttgaggt
      421 agaattgcca cgtgtcaatt tttatgaagg cttgaaaaat ggaaacttgg cttcttctat
      481 tgttcatttg actgataatt tagacttgat ccctggcacg tttgatttga tgttactgcc
      541 aaaattaact cgctcatgga cttttgaaaa tgaaagtaga ttgcttgcta ctcttttagc
      601 acctttaaaa agtgactatg atctcattat tattgatact gtaccaacgc caagcgttta
      661 tacaaataat gcaatcgtgg cgagtgatta cgttatgatc cctttacaag cagaagaaga
      721 aagtacaaac aacattcaaa actatatttc ctatttgatt gatttacaag aacaatttaa
      781 ccctggacta gatatgatcg gttttgttcc ttatttagtt gatacggaca gcgcaacgat
      841 aaaatcaaac ctggaagaac tgtacaagca acataaagaa gataacttgg ttttccaaaa
      901 tattatcaag cgaagtaata aagtaagtac ctggtctaaa aatggaatta cagaacacaa
      961 aggctatgac aaaaaagttt tatccatgta tgagaacgta ttttttgaaa tgcttgagcg
     1021 aattattcaa ttagaaaacg aaaaagaata gaatcacaaa tcacaagtga ttaatcacaa
     1081 atcacttgtg atttgtgatt gttgatgata aaataagaat aagaagaaat agaaagaagt
     1141 gagtgattgt gggaaattta ggcgcacaaa aagcaaaacg aaatgataca ccaatcagtg
     1201 caaaaaaaga tataatggga gataagacgg ttcgtgttcg tgctgactta caccatatta
     1261 taaaaattga aacagcaaaa aatggcggaa acgtaaaaga agttatggat caagccttag
     1321 aagaatatat acggaaatat ttacctgata aactttaaaa aggagtgaaa atgaaatggc
     1381 agttacgtat gaaaaaacat ttgaaataga gatcattaac gaattatcgg caagcgttta
     1441 taatcgagta ttaaactatg ttttgaacca tgaactagat actaaaaata ctcgtttact
     1501 agaagtgaat cttttaaatc aattagaagt ggcacaagaa gttgatttat ttcaacaacc
     1561 atttgaagaa ttacaagcta ttcatgagta ttggcggtca atgaatcaat attcaaaaca
     1621 aattttgaca aaagagaaag tggcttaaca tggcgaatat tactgacttc accgaaaagc
     1681 aatttgaaga tcgtttagaa aagaatgttg aacgactaac taaaaataga ctagcggttg
     1741 aatcgccaac cgctttttta cttggtgggc aaccaggatc aggtaaaact agtttgcgat
     1801 cggcaatttc cgaagagaca caaggaaatg ttgttatcat tgataatgat acgttcaaac
     1861 aacagcaccc taattttgat gaactagtga aactttatga aaaagacgta gtaaaatacg
     1921 ttacccctta ttctaatcgc atgacagaag cgatcataag ccgtttgaga gataaagggt
     1981 ataatttagt gattgaaggt acaggacgaa caacagacgt tcctattcaa accgcaacaa
     2041 tgcttcaagc caaagattat gaaacaaaaa tgtatgtcat ggcagtacct aaaatcaact
     2101 catatttagg aacaattgaa cggtatgaaa ctatgtatgc agatgatcca atgacagcca
     2161 gggcaacacc aaaacaagcg catgatattg ttgtcaaaaa cttaccgacc aatttagaaa
     2221 cccttcataa aacgggctta tttagcgata taaggcttta caatagagaa ggagtgaaac
     2281 tctattcaag cttagaaacg ccttccatta gtccgaaaga gaccttagaa agagaattaa
     2341 atcgtaaagt atcagggaaa gaaattcaac cgactttgga gagaatagag caaaaaatgg
     2401 ttcaaaatca acaccaagaa acccctgaat ttaaagcaat tcaacaaaaa atggaaagct
     2461 tgcagccacc tacaccacca atacccaaaa cacctaaact tccagggatt taaaccttaa
     2521 aaaagtaaaa gagtagttac caaaaaacgg taactactct ttttttataa aaacatttcc
     2581 tcatttttta aaagctgatc gagaaataaa gcacacaact gtattctttc ttttttcagt
     2641 tggtacattt tgcagtctgt aacgtgccat ttactgtttg ttaccttaac atatccagtc
     2701 gaaaacacaa gggtatataa acgagcaagc tcgcccttgt gttttctttg tgtctatgtt
     2761 gcgttctcgt cacagcaaac gacacgaaca cactggcgaa aatgaaccaa caaaacgaaa
     2821 aaagaaagga gcgtacactg taatttattt ctagctttta aaacatgagg aaaacagctt
     2881 cacttcctca aacgcctaac aaaaatggtt gtcaaaaaac taaaaatcaa aaaaagaaaa
     2941 gaggaaaaga aaatggaaaa aacaaaaaaa ttacaattag aagattttac agaaaatgg
//
LOCUS       DAZKCW010000136         2871 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000136 DAZKCW010000000
VERSION     DAZKCW010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2871
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.143"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..268)
                     /locus_tag="ACG84Z_002776"
     CDS             complement(<1..268)
                     /locus_tag="ACG84Z_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163561.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKI"
     gene            complement(285..1490)
                     /locus_tag="ACG84Z_002777"
     CDS             complement(285..1490)
                     /locus_tag="ACG84Z_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFP9163562.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            2184..2570
                     /locus_tag="ACG84Z_002778"
     CDS             2184..2570
                     /locus_tag="ACG84Z_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFP9163563.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            2664..2855
                     /locus_tag="ACG84Z_002779"
     CDS             2664..2855
                     /locus_tag="ACG84Z_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163564.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
BASE COUNT         1035 a          458 c          363 g         1015 t
ORIGIN      
        1 atattttagc atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa
       61 tatgactgat agattctcta gcttcttcac ataaactttt tactttatta attactactt
      121 tgtcatattc atttaacaca ctattattac cattacttag acgctcagat tctacgaaac
      181 aactcaaatc agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct
      241 ccaaactacg taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg
      301 aaattgtcca ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat
      361 actctcgaaa agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta
      421 tggtttgatt tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa
      481 atcgtaatat gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa
      541 taattagcta tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg
      601 acagaagaaa ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa
      661 taaacaatcc cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt
      721 tcttgtatca aagcatctct actttgatac gcttctatta tatccattcc taatgttata
      781 gacgtttgtg ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta
      841 tctccactaa cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt
      901 cgaatatctc catttttaac atattccagt attttatttt cataaagaaa cagatatatt
      961 tctggatcgt aattttgtga taacagatta tctattttga tttgctcgat agttttactt
     1021 agattttctg tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa
     1081 aaataatgaa ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt
     1141 tgcaatgaat tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt
     1201 agtttaaaaa aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg
     1261 gttttaaaca tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct
     1321 ttagtttttt taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt
     1381 ctatctgagc gatactcttt tataatactg aattcggaat taaaaaccac gataggtaac
     1441 tttaaacaaa catgaagaga ctttaataag acttctttat ctgaaaacac ttttgtttct
     1501 ctctttcctt tctacatcat taaatagtat tttatacgtt atctaaaata ctattcctct
     1561 gtcaaaataa gctaacttac ttcattataa aatatccact tatcgctttc atgtatattc
     1621 caccgtaaaa agtacatttt atcaccgaga actcatcatt tttcatcatg atgaatacta
     1681 tttacatata tctagttcaa agacaataat tattatgatc cgttattatc taagcactat
     1741 acagataata ggaatttttc gtttctaaat attccaattt gggaatccaa taaaaatttt
     1801 cgttcaaata cgtgtctatt cgaactcttt tctagttgtt aattatgaag ggggaagaaa
     1861 taaaaaatac aatctataca cgaataagaa tattatccaa aaggaggttt tagaaaagat
     1921 ttattatacg taaaaagctc aagacatttt cttagccata aggacatgtt tgatatttaa
     1981 gaagatatat gaattttctt ttctaagtat aaagataact atccattatc aactaaaaaa
     2041 acatttttga aaataaacat cagcagtcct atcaatgcat gtgagcttat agaagttatt
     2101 cgcagcgcag cataattgca ttagcttctt ttcgtgtttt ttgcctcttt tccctttaaa
     2161 tcttaatgga ggaggtgtgc aatatgtcag ataacgacga acgcgtaaat gcccagttga
     2221 ttcgattctt tgaaaaggtc attttgaaca ccgctaatac ttattataaa aaacaagaag
     2281 aaattcaaaa acatgaacaa cttgatcaac tcccaccata tttgtttact aaagatacta
     2341 taaaatttaa acaaccgatt aatgttttaa atgtgactct ccttgttgaa gatataaaat
     2401 tagcaaaaat ccttcctttg ttgaaagaac ctgaacaaat ttttcttatc gaaaaattta
     2461 tctttgataa aactgataaa gaaattggaa aggttctggg gattacaaga cagggtgcga
     2521 caaatttaaa acatcgactt tacaaaaaaa ttcaaaaaat gctggtttaa tatctgcata
     2581 ataactaatt ttgtatgctt ctttgctcgt tctcctcctt cccaaagaaa tagattataa
     2641 gtccatggga agaaggtaga tttatgaatt ctttaaaaga agatttcatt ttagcaaagg
     2701 ctggaaatga agaagctgtt gaggcaattc tcaaaagatt tagctctttg attcataagc
     2761 aatcctggag aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat
     2821 atctagctat ctcgaaattc gaaattaaag aataactcaa ctaagggagt c
//
LOCUS       DAZKCW010000137         2690 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000137 DAZKCW010000000
VERSION     DAZKCW010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.144"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            146..1549
                     /locus_tag="ACG84Z_002780"
     CDS             146..1549
                     /locus_tag="ACG84Z_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFP9163565.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPI
                     LSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGP
                     QMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGD"
     gene            1898..2530
                     /locus_tag="ACG84Z_002781"
     CDS             1898..2530
                     /locus_tag="ACG84Z_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFP9163566.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
BASE COUNT         1023 a          380 c          519 g          768 t
ORIGIN      
        1 aaaggcagta acaggattaa acattgaaac ataatcgtta ctaaatgaaa tcaagaaata
       61 tactgtatta ctcaattcat tgaaaatatt tatcataatt tttaatagaa aacactatta
      121 aagagaaaaa agagaggtaa atcaaatgaa aaaatcttta aaacttgcat cagcagttat
      181 attaatgtcc caactcctta tagcaacacc tttccatgtg ttggcaagcg aaaattcaac
      241 atacaaaatt gcaaaagaaa gaaccgagac gactgaaatg agtaattccg atgtaacagc
      301 agagagtagt gaacttttga caacttcatc aagtgaaagt agtacgactt caaatgccga
      361 gtcttcaaca acttcatcaa gtgaaagtag tacgacttca aatgccgagt cttcaacaac
      421 ttcgtcaagt gaaagtagta cgatttcaag taccgaatct tcaacaactt caagtagtac
      481 aagtgaaata acttcttcga aagtgacaaa accaaaccat atagaatctt caaaaaagga
      541 agcgccaaaa acggaaggac aaacaaaaac tttttcgaca ccacagcaaa tagaatcaac
      601 agaatctttc caatcacaac caatactatc tggtaatgaa gaaattcatt ttgacaaaaa
      661 tgaatctgta gaaaatttta ttatgaaaat tggtgagtct gcgagaaaaa ttggtcagaa
      721 atatgattta tatgcttctg ttatgattgc acaagcgatc ttagaatctg ccagtggtca
      781 aagccagtta gctcaggcac cgaattacaa tttatttggg ataaaaggaa cttataatgg
      841 aaactttgtc attatggtaa caaacgaaga tttgggtaat ggaacgcttt atacgaccca
      901 atcaaaattt agagtgtatg aaaactatga ggaaagcttt gaagattatg ccaaattatt
      961 aactaaggga attagtggaa ataaagattt ttatgcagga gcattaaaag ctaatagtaa
     1021 aacatatcga gaagcaacta aattccttac aggacggtat gcaacagata cacaatacta
     1081 tttgaagcta aatgaattaa ttaaaaccta cgatttaacc aactatgata aagaagttaa
     1141 aggtccacaa atgagtaaga ctggatacca agtgcctatt cataattatt caataaccag
     1201 tttgtttgga aatcgtggaa atgaatttca ccgaggactt gatatggcag ctacacaggg
     1261 tgagccgatt catgcagtta aagctggtaa ggttgttaaa gcagagtttc actactcttg
     1321 gggaaattac gtggtgatac aacacgaaga tggatcaacc gcgttatatg ctcaccagca
     1381 acaataccta gtaaaaactg gagataatgt tttgcaagga caaataattg gctatgtagg
     1441 aagtactggg aatagtactg gcccacacct tcatttggaa atttgcaaag atagtagtct
     1501 ttctcagagc atgttagttg atccgaaaac cttattattc ggagactaaa aaaggtaatc
     1561 aatctgacaa agtaacaaga aaatggttgg attcttagac ctttgatcag gatattgaga
     1621 ctggaattga tatctcgatt acgatgggtt tgacaaataa aacaagtcca ttatcgaata
     1681 tcgagtgtat tattgccgtc tttatgctca tattttgagc aggtttcact agatgaaaac
     1741 aatttatcta tcttgaggat ttcgtgtacg tatcgttcag tcttgtattg taaattagtc
     1801 ataaaatcag actaagaaaa attggaaata tttttttctg atttattaaa agttaattga
     1861 aattatatgg tacttctttc ttgggagggt aggtgcagtg aaggaaagat atggtcacct
     1921 tactgttgtt gaggagatta ctcataatgg atataaaaaa tatcgttgcc tatgtgactg
     1981 tgggaatgaa acgattgtat atcgatcaaa cttactaaca ggtagaacca aaagttgtgg
     2041 atgtggaaat tataaaaata ggcataaata taaaaatttg acaaataaaa cttttggtaa
     2101 gttagttgca atcaagccaa ctaaactgcg aagtgaagga actgttgttt gggaatgtca
     2161 atgtctgtgt gggagaaaaa agttagtatc ggcaaagcga cttctaaaag gtgatgtaaa
     2221 aagctgtgga tgtttgaaat caaaaaagca tcacattgaa aataaaaaat tcggattact
     2281 tactgcaaag tatcctttgg acaataactg ttcatggaaa acaaaatggg tttgtcattg
     2341 tgagtgtggc agtatgtgtg agataagtta tagtaactta ttttttggac atactcaaag
     2401 ttgtggatgt ttaaaaaggc aagaaacaag gacatgtgtt gaagggacag taatagagtg
     2461 tctaacgtca aaattaccga aaaataatac aagtggtgtt aagggagttt atcgttctaa
     2521 agagaaatag attgcgtata taactttaaa aaaaaagagg tactatttag gatcgtatga
     2581 ttctattaag agtgcagctc aagctagaaa agatgctgaa aataaattgt ttcaaccttt
     2641 gattgacaaa tatcgaggta atcattaatt attgtggata ataattaaca
//
LOCUS       DAZKCW010000138         2670 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000138 DAZKCW010000000
VERSION     DAZKCW010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.145"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(185..487)
                     /locus_tag="ACG84Z_002782"
                     /pseudo
     CDS             complement(185..487)
                     /locus_tag="ACG84Z_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            580..929
                     /locus_tag="ACG84Z_002783"
                     /pseudo
     CDS             580..929
                     /locus_tag="ACG84Z_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1201..1491)
                     /locus_tag="ACG84Z_002784"
     CDS             complement(1201..1491)
                     /locus_tag="ACG84Z_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163567.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1699..2390)
                     /locus_tag="ACG84Z_002785"
                     /pseudo
     CDS             complement(1699..2390)
                     /locus_tag="ACG84Z_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          787 a          488 c          378 g         1017 t
ORIGIN      
        1 aagtgcgaac ggaataattc atttaaatcg cctttagtga ctagagtttg cacaatttct
       61 gtagtaaaat cattcatagg gaagtcctct tttctgtgaa ttggttgtcg ttaactttat
      121 tctacagaag ggacttcctt ttttgtatgg attttttcat ttacacaaaa tattttatac
      181 tctcaacata cttgcaaagt aatactacaa ttcctaacat aatcgtagaa tttaataatt
      241 tccatagcat aaagtgttta gaaaagaaca ttaagaatag ttctataata attcttgaac
      301 tccatgtctt ataatgttct atcgaagcac ccaaatagcc aagttcatct aatctacttg
      361 cataaactac gtcatccgct ctcatagtcg gcatatacat attaaagagt aaaaagatac
      421 cccaaatccc tattagtaac aagatcagtt ctttgttatt cgttattttt ctattatgtt
      481 tgttcatttt tatactcctt cttatatttc ctaatagagt ataacatagc tttaagcatt
      541 acttaaagat aacttaaaag ttatctttta aatacttaat tgttaaatac cttatttgat
      601 gcaaaagaaa tctacgatag tcaacaaaaa aattttcatt atatccagaa aaatttttct
      661 tagttaagga cctatggatt gcagtaatgc agaattcgtc gaataaactg ccaaagacat
      721 acaatcatat tgcttttaaa attgacgaac aagatataga ttcgtttgtc tcaaaaatcc
      781 aaatgttagg tttaactgtc gaaccaggac gttctcgtgt gaaaggcgag gcttcttcaa
      841 tttactttta cgactatgat aatcacctct tcgagttaca taccggtact ctccaggaac
      901 gtttaaaatc ctacaattcc actacctgag actagtaatg actagtctct ttttatggcc
      961 tctgatcccc ccattgagcg aatactaata gggcttcgaa ttgatctgtt caatctttaa
     1021 gcaatatccc tcaaatgagt ttggaaagtt tagtgattca tcacaaatac ttaaatacat
     1081 gtagttatat atagattgag gttcttgtga gcgtatgctc gtgtgggttc aaatcccatc
     1141 gtctgcatcc atctttccaa aacaagcggc taggacattt ttgtctcagc cgcttgtttt
     1201 ctagtttatt ctttcatctt gtcggacctt ttttcttggg tatagacttt tctcatattc
     1261 taccacaatt ttgggtttcc ctaacacatg ataggatctc acaacaaatt gctttctatt
     1321 attataataa cctgtaacga ctaacttcat cccttcgtct acttcagcta ggaagttcaa
     1381 actatgggaa gcaatcaaac aattgacccc atttaaactg aaacggatca acggtctggc
     1441 actaacttgc aaagtacgga tcttatctac tgttccatat tttttctcca taaccttcac
     1501 ctcaatacca ttatacgaac atacattccc tttgtaaaga agaaactctg ttttatcttt
     1561 ttgacttttt gtctattacc tttcttaaaa tcatattggc acttcctgcg aagatgaagg
     1621 acatgtacta aaaaaaagag gcagcagtat agattactgt tgcttcttta ctaatttagg
     1681 tttacttgtt aagaaagatt atttacgcaa atgttcttca acaatttgct gagatttatc
     1741 agctgtatct tccacttcat cttttgcttt ttctaacttt tgaatatatt gtttcaagct
     1801 tgagttttca gcagttgctt cgtctaattt cttttgtgta tctgttaact gatttctaca
     1861 tttgtttttt cttgtgtcag tgttgcgatt tgttgattca aaccatttac agtattttgt
     1921 aattctgaaa gttttgcttg tgcttcttgt agtcttgctg tccaatctgc attcagatga
     1981 ttgatttcat catttttttg gttgatctca tctagtttga cattgatttc attttgtttg
     2041 ctttgtagtt gtgcatcctt gctgactaat tgactttcta agttttgttt ttctgctgcc
     2101 gattgatttt tttggttttc taattcattt acttttgttt ggtattcttg gacatctgcc
     2161 tttgaatctt gcaatgtctg ttctttttgt gctagtcgag cggtaagatc tgtaatcgct
     2221 tgctctttat ctgtcaatgt atgatcaagc tgtgtcagat tctcattgat tgtatcaata
     2281 tctgtctctc caccccacaa aataatttca tttgcgtacc gcgtgcctgt gtagccaatt
     2341 agacatagaa atgcaacgac aatcccacca gtaataaatt tctttttcat ttgcatagct
     2401 ccttaatcca atacttttac atgctaaaag taagtgatct caaacacaat gtcaagcgtt
     2461 tttaaattac atatgtaatt ttaatataaa tactatcaaa tactcattta atcctccttt
     2521 tttatctatt taaaaaatct tttttataga gaaaaatgca ggttaatact ttcttaaata
     2581 aatatttatg gtgaacaaaa acaaaaaagc aagttttatt aaacgtaacc cttttcattt
     2641 catagattac tgtatttatt acaaaaaacg
//
LOCUS       DAZKCW010000139         2652 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000139 DAZKCW010000000
VERSION     DAZKCW010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.146"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>2652)
                     /locus_tag="ACG84Z_002786"
     rRNA            complement(<1..>2652)
                     /locus_tag="ACG84Z_002786"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          551 a          802 c          557 g          742 t
ORIGIN      
        1 gggaaatctc atcttgaggt gggcttcaca cttagatgct ttcagcgttt atcccttccc
       61 tacatagcta cccagcaatg cccttggcag aacaactggt acaccagcgg taagtccatc
      121 ccggtcctct cgtactaagg acagctcctc tcaaatttcc aacgcccgcg acggataggg
      181 accgaactgt ctcacgacgt tctgaaccca gctcgcgtgc cgctttaatg ggcgaacagc
      241 ccaacccttg ggaccgacta cagccccagg atgcgacgag ccgacatcga ggtgccaaac
      301 ctccccgtcg atgtggactc ttgggggaga taagcctgtt atccccaggg tagcttttat
      361 ccgttgagcg atggcccttc catgcggaac caccggatca ctaagcccga ctttcgtccc
      421 tgctcgactt gttggtctcg cagtcaagct cccttctgcc tttacactct tcgaatgatt
      481 tccaaccatt ctgagggaac ctttgggcgc ctccgttacc ttttaggagg cgaccgcccc
      541 agtcaaactg cccatctgac actgtctccc accacgatta gtggtgcggg ttagagtggc
      601 cataacgcag gggtagtatc ccaccagcgc ctccatcgaa actagcgttc cgatttctac
      661 ggctcctacc tatcctgtac atgcggtaca gacactcaat atcaaactac agtaaagctc
      721 catggggtct ttccgtcctg tcgcgggtaa cctgcatctt cacaggtact aaaatttcac
      781 cgagtctctc gttgagacag tgcccaaatc gttacgcctt tcgtgcgggt cggaacttac
      841 ccgacaagga atttcgctac cttaggaccg ttatagttac ggccgccgtt tactggggct
      901 tcaattcgta ccttcgcttg cgctaagcac tcctcttaac cttccagcac cgggcaggcg
      961 tcagccccta tacttcatct tacgattttg cagagacctg tgtttttgat aaacagtcgc
     1021 ttgggcctat tcactgcggc tgatcgtatg atcagcaccc cttctcccga agttacgggg
     1081 tcattttgcc gagttcctta acgagagttc tctcgctcac cttaggattc tctcctcgac
     1141 tacctgtgtc ggtttgcggt acgggccgct gttttctcac tagaagcttt tctcggcagt
     1201 gtgacatcag gaacttcggt actattattt ccctccccat cacagcttgt ccttaagaaa
     1261 agaagcattt gactcctctt cagacttact gcttggacag acatttccga tcgtctgcat
     1321 tccttagcct cctgcgtccc tccattgctc aaacaaaaac aacgggtaca ggaatatcaa
     1381 cctgttatcc atcgcctacg cctgtcggcc tcggcttagg tcccgactaa ccctgggcgg
     1441 acgagccttc cccaggaaac cttagtcatt cggtggacag gattctcacc tgtctttcgc
     1501 tactcatacc ggcattctca cttctaagcg ctccagcagt cctcacgatc tgccttcaac
     1561 gcccttagaa cgctctccta ccaatacacc taaaggtgta ctccacagct tcggtaatat
     1621 gtttagcccc ggtacatttt cggcgcaggg tcactcgact agtgagctat tacgcactct
     1681 ttaaatggtg gctgcttcta agccaacatc ctagttgtct gtgcaacccc acatcctttt
     1741 ccacttaaca tatattttgg gaccttagct ggtggtctgg gctgtttccc tttcgactat
     1801 ggatcttatc actcacagtc tgactcccgg atatgaatga atggcattcg gagtttatct
     1861 gaattcggta acccgagatg ggcccctagt ccaaacagtg ctctacctcc atcattctca
     1921 attccgaggc tagccctaaa gctatttcgg agagaaccag ctatctccaa gttcgtttgg
     1981 aatttctccg ctacccacac ctcatccccg cacttttcaa cgtacgtggg ttcggtcctc
     2041 cagtgcgttt taccgcacct tcaacctgga catgggtaga tcacatggtt tcgggtctac
     2101 gactacatac tcaaacgccc tattcagact cgctttcgct gcggctccgt ctcttcaact
     2161 taacctcgca tgcaatcgta actcgccggt tcattctaca aaaggcacgc catcacccat
     2221 taacgggctt tgacttgttg taggcacacg gtttcaggtt ctatttcact ccccttccgg
     2281 ggtgcttttc acctttccct cacggtactg gttcactatc ggtcactagg gagtatttag
     2341 ccttgggaga tggtcctccc ggattccgac ggaatttctc gtgttccgcc gtactcagga
     2401 tcctcctagg tgtcttccac atttcgtcta cggggttttt accctctttg actgactttt
     2461 ccaagtcatt cgactatctg aaagaactac catattggag tcctacaacc ccaacaagca
     2521 agcttgctgg tttgggcttt tcccgtttcg ctcgccgcta ctcagggaat cgaattttct
     2581 ttctcttcct gcaggtactt agatgtttca gttctctgcg tctacctcga atgtgctatg
     2641 tattcacaca at
//
LOCUS       DAZKCW010000140         2588 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000140 DAZKCW010000000
VERSION     DAZKCW010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.147"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1412
                     /locus_tag="ACG84Z_002787"
     CDS             <1..1412
                     /locus_tag="ACG84Z_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFP9163568.1"
                     /translation="PTVEGEKVEVGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTN
                     TPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNV
                     TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNA
                     DKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTY
                     PDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYT
                     WKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTG
                     KTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNV
                     VVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGL
                     ILLGTLGLLGYKNRKKENE"
     gene            1546..>2588
                     /locus_tag="ACG84Z_002788"
     CDS             1546..>2588
                     /locus_tag="ACG84Z_002788"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFP9163569.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTAR"
BASE COUNT         1016 a          363 c          520 g          689 t
ORIGIN      
        1 aaccaacagt agaaggcgaa aaagtagaag ttgggggcac agtagatcta acagataatg
       61 ttactaactt gccagcgtta ccagaaggaa caacagtaac agatgttact cccggcggta
      121 caattgatac caacacacca ggtaattacg aaggtgtcat tgaagtaacg tatccagacg
      181 gtacgaaaga tacggtgaaa gttccagtag aagtgacaga caatcgttct gacgccgata
      241 aatatgaacc aacagtagaa ggcgaaaaag tagaaattgg aggcacagta gatttaacag
      301 ataatgttac taacttgcca gcgttaccag aaggaacaac agtaacagat gttactcccg
      361 gcggtacaat tgataccaac acaccaggca attatgaagg tgtcattgaa gtaacgtatc
      421 cagacggtac gaaagatacg gtgaaagttc cagtagaagt gacagacaat cgttctaatg
      481 cagataaata caatcctgaa ggacaaaaag tgactacaga cttaaataaa gagccagatg
      541 catctgaggg aattaagaac aaagaagatt taccaaaagg aactacttat gcttggaaag
      601 agaaagtaga tgttagcaca gctggaaata aaaaaggtac tattgtagtg acatatccag
      661 atggatcatc tgatgaagtt gaagtagacg ttacagtgac agatactcgt tccgatgcag
      721 ataaatataa tcctgaagga caaaaagtga ctacagactt aaataaagag ccagatgcat
      781 ctgagggaat taagaacaaa gaagatctac caaaaggaac tacttatact tggaaagaaa
      841 aagtagatgt tagtacagct ggaaacaaaa aaggtactgt agtagtaaca tatccagatg
      901 gatctaaaga agaagtagaa gttactattt ctgtagtaga taaaaaagca ccgaataaac
      961 ctcaagttga tcctattaca gagggtgacc aaattgttac tggtaaaact gaaccaaatg
     1021 cagaggtgac agttacatta ccagacggaa gtcaacacca tgggacagct gataaaaatg
     1081 gtaattttac agttaaagtt cctaaattag aggcagggac aaaagtgata gtaactgcaa
     1141 ctgatgaatc tggtaatact agtgaaccta ctaatgtagt tgtttcttcc aacaaaaaag
     1201 acagtggaaa aaacggtagt aaaggtagta agactgacaa tcaaggtagc aacagcaatc
     1261 aagacaaaaa tagaggcaaa agccagtcct caaaagtttt tcctaagacg ggagagagtg
     1321 acagtaatat ctttactatt agcggtggtt taatactgtt aggaacgtta ggattattag
     1381 ggtataaaaa tcgaaaaaaa gagaatgaat agaaaatcaa tttcttaagt cttctctgag
     1441 aagaggaaga atctttttct tcctcttttt gcttttttat gatgggaaat aagtgttagt
     1501 taaagatgaa tatacttttt atagaaagga aaagaatgta attaagtgga aaaaatagta
     1561 attattggtt caaaccattc agggctagcc gcagctcgat ttctaaactt aagcgattca
     1621 aattatgaag ttattctaat cgataaaaaa tcagaaatta gttacttgga atgtgggaca
     1681 tcgttattta taaaaggaga agtaagtaat ttagaagatc ttttttatca aaatagaatg
     1741 acactaaatt ctgagataaa aaagttattt ctagagacag aagttgacaa aattgatatt
     1801 caaaataaaa agattagttg tgtaaaaaaa gatggtacaa gattctctca agaatatgac
     1861 aaagttatat tagctacagg ttcaaagcaa attatgctag atataccggg gaataattta
     1921 gctaatattt tttcgataaa gaattttcca aatgcaaaag agatttttaa agctttggat
     1981 gatagtacta ttaaaaaagt aggaattatt ggagcaggat atattggagt tgaaattgct
     2041 gaagccataa gaaaaagagg gaaagaagta tatcttttcg atgttgcaga tagagtgttg
     2101 tcgacttatt acgaccgtag tttttcagat aaagttgaag aaatactatc aaaaaatgga
     2161 atacatcttt gtctatcaga aagtcctaaa aaatatttag gaagaaaaaa gattgaaaaa
     2221 atagtcacta caagtggtac ccaatactct atggatatgg tcgtacaagc tataggattt
     2281 ctatctaata gtccaattgg ggaaaaggaa ctcttgagag atgttagtgg agcatatcta
     2341 actaatgaat accagcaaac aaatataaaa gatatatatg ctattgggga ttgtgctaca
     2401 acttttttta cgtccattaa tagaagtagt gttgattttt ctatttctaa tgctctaaga
     2461 acagcttata ttgcaactca acatattaac aatcaagatt ttacaccttc tggttcccaa
     2521 tttacaaatg gcttttctat atttaattac aatttttacg cagcaggttt gaatttaaaa
     2581 acagcacg
//
LOCUS       DAZKCW010000141         2491 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000141 DAZKCW010000000
VERSION     DAZKCW010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.149"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1335
                     /locus_tag="ACG84Z_002789"
     CDS             <1..1335
                     /locus_tag="ACG84Z_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163570.1"
                     /translation="IDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1322..>2491
                     /locus_tag="ACG84Z_002790"
     CDS             1322..>2491
                     /locus_tag="ACG84Z_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HFP9163571.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKN"
BASE COUNT          831 a          377 c          420 g          863 t
ORIGIN      
        1 atagatgctg cttttttatt tagttgttta tatacttttg caacttatcg aacagttgat
       61 atctattatc gatccgcaat tgcagaagca atcgctctta cgattatccc agctgtttta
      121 tattatgctt atggattgat attcaataga gaaaaaaaag tcatcgcttt atctgtcagt
      181 ataagtctac ttgtgtatac tcatgtctta actacactat tgtgtagtgc attgattgct
      241 tgtatgatta tagttcgttt gtttttaagc aagcaaataa aaaacgatat aaaatttgtg
      301 gtcgtgaatt tagtaaaggc tgtttttttg acttgtgcat taactagcta tttttggtat
      361 cctatgttgc agcagatgaa ttatcaagaa atacacagtc ccttcaaaac agatttgcag
      421 ctagaagcac tttctatttc agatagtatc attcaagcgt taaataacga tattacaaca
      481 tacactatgg ggttattagg attggttgcg ttgatttttc ctttattcat actgaaagaa
      541 atggagaaaa aagaaaaaat catctatgtt ggcgtagttt ctacatgggt atgcgtaact
      601 aatttatttc catggttttt gtttcaaaaa acaccgataa gcttactcca gtttccttgg
      661 cgtatcttag gtatccaaat ctttttttct tcaatgatca taacgcttgt ttttatgaaa
      721 aagactatga ataaaaaata ttcatggtta atcattggcg ctactgtggt gtttctactc
      781 gtcacgtcta tagcagcaaa agaaaattac gcaaaagtta tccaatcaaa acacggtcat
      841 attgttatca atgaagaaac actcccacgt tatacaacat cagatatggg aggattatac
      901 gattacgccc caacagaagc gataaaagaa aggcctcact tagaaaaaca tgaagtaaaa
      961 gtaggagaat cgtgggaaaa agggaagtat aaagctgcag ataataacat tacttacaca
     1021 gtggcaagca acaaaaagca aaaagtgaca gtaccagtat atgcttattt aggtacacag
     1081 gtaaaagtaa acggtaaagt cgtaaatgac tcttataaaa aacatggctt agtgaatgtg
     1141 gatgtaaatg ctggagaaaa taagatagaa attacaacaa aatatactcc aactgctctc
     1201 atggctttat ggatcagtat tctgacttat tgtttagtgg tgtattcaag ttttaaacga
     1261 tttgcaccta ataagttgaa agattctcga tatgtgacta aaaaggagat aaacaagaag
     1321 aatgaaaata aataaaaaag tagtaatatt gagtggatta attatagtta gtagtatata
     1381 ttctttcatc tttttcaaaa atacacagag tatttatacc actggagatc tttcttttca
     1441 cttatctcga atcaaggggt tatcgactat ttttaccagt ccgattaatt atgagacatt
     1501 caattatact ggatatggtg taaattattt ttatcccttt ctgacttttt ttccagctgt
     1561 aatgttatat tggatgacaa aaaatttgat tgtaagctat attatttacg tttggttatt
     1621 gaacttgtgt acaacactcg tagcttatca ttatggcgag cggtttttaa aacaaaaaaa
     1681 agcggcattt ttatttagtt gtctctatat tttctctgct tatcggacag tagacatcta
     1741 ctatcgttcc gcaattgccg aagctatcgc aataacactt gttatccctg tattatttta
     1801 tgcttatcaa atcatctctg gaaaagaaga aaagtatccg tctgtaaagc tagcattgag
     1861 tatgagtttg ctagtgtaca gccatgtact atcaacatta atgagtacag cattaattat
     1921 catttttatt tttattcgtt tggtttctaa aggtttcaag aatgcagatt ttattgctat
     1981 atttaaaaaa ttatttagtg cggcaggaat gacattggtt ctgacgagtg ctttttggta
     2041 tccgatgttt gaacaaatgc tctaccaaaa aatcaacaaa cctagcgtga caaatttata
     2101 tgctcatgca tctaatgtgt tcgatagtct gactgaagct atgaacaacg acttaactac
     2161 ttactcaatg ggactagttg gtctgttatc tttatgtatt cccctgattt tatttaaaaa
     2221 attaacaaac atagaaaaaa agatttatta tggtacgtgt ttgacttggc tagctacaac
     2281 tagtttggtg ccatggtatc ttctgcaaaa tacgccagcc aaattgttac aatttccttg
     2341 gcggatctta agcttgcaaa taatattctc ttctctgata ttaacgatga tatttttcaa
     2401 aaatagaaga tacaataaga caagagaact attttattta tttatgactg ttttgttatt
     2461 aatcacttta actgtttcta gtaaaaaaaa t
//
LOCUS       DAZKCW010000142         2459 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000142 DAZKCW010000000
VERSION     DAZKCW010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.150"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..1150
                     /locus_tag="ACG84Z_002791"
                     /pseudo
     CDS             6..1150
                     /locus_tag="ACG84Z_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            1321..1779
                     /locus_tag="ACG84Z_002792"
     CDS             1321..1779
                     /locus_tag="ACG84Z_002792"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFP9163572.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..2408
                     /locus_tag="ACG84Z_002793"
     CDS             1938..2408
                     /locus_tag="ACG84Z_002793"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFP9163573.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          823 a          460 c          460 g          716 t
ORIGIN      
        1 gaaacatgca cattcaaaca aaattgatcc acggaggcat cagtgaagat cccacaacag
       61 gagctgtcag tgtacctatt tatcaaacat ccacttatcg gcaagatggc gtcggccagc
      121 ctaaacaata tgaatattca agatctggta atcctactcg ttttgcattg gaagaactga
      181 ttgctgattt ggaaggcggt gttcgaggat tcgctttttc ttctggtctt tctgggattc
      241 atgccgtttt ttctcttttt caagctggcg atcatatctt attaggagat gatgtctatg
      301 gaggaacatt ccgtctattt gacaaagttc ttactaaaaa tggtctcgag tacacgatca
      361 tagatacgag taatcttgat aaaatagaac aatccatcaa acccaataca aaagcacttt
      421 atcttgaaac acctagcaat ccgcttctaa agattactga tttagaaaaa agtgccactc
      481 tggctcatca acatggattg atagttattg ctgacaatac atttgctact ccttattttc
      541 aaagaccttt agatctcggt tctgatatcg ttgtccatag cggtaccaaa tatctaggcg
      601 gacacagcga tgtagtagct ggtttagtga cttctaacca aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttctttaact taataaaaat aaaaaaagat gaactatttc tagttcatct ttttgcctt
//
LOCUS       DAZKCW010000143         2452 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000143 DAZKCW010000000
VERSION     DAZKCW010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2452
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.151"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(11..295)
                     /locus_tag="ACG84Z_002794"
     CDS             complement(11..295)
                     /locus_tag="ACG84Z_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163574.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            complement(995..1090)
                     /locus_tag="ACG84Z_002795"
     CDS             complement(995..1090)
                     /locus_tag="ACG84Z_002795"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFP9163575.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            1765..>2452
                     /locus_tag="ACG84Z_002796"
     CDS             1765..>2452
                     /locus_tag="ACG84Z_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFP9163576.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLP"
BASE COUNT          798 a          393 c          456 g          805 t
ORIGIN      
        1 tttctcatgg ttatatcatt cctccgataa gcatttcaat gatttgatta tttgtgtaga
       61 catactcgct taatatttga gtattttctg tttggatagc aataaattta tcgagcaata
      121 aatcgaattg gtcttttttg taagtcgtaa gttgacggtc aaaatcactt tcgattaaaa
      181 cttttagata tttatttcga ctccattttt ctcctgtttt attcgtgagt tcttggcaac
      241 gtttgtctat tgttgcaaca aactttggat caatattccg aactaaaatg tccataaaaa
      301 atctcctttt gcaattatgt ataatttatg tataccatac aaatactata tttgtatagc
      361 tgttttttgc caaaatgcta tacataagct acccacgatg gcgaaaaagt gatatcaaat
      421 ttttttctga gaaacgtgat aggcacagcc tatctaccca ctttttttag aaagtgggta
      481 cacgtttcct tatgctcttt aaaattcggg ggggagtgct gcacgtgtaa tcgataacca
      541 aatttaacag acgaaaaatt gttggaatat aaaaatatga cacccgaaag aaaacgatcg
      601 ttggaaaaat taatgcaact agtgaacgaa gacggcggaa tttcagacgc agcttttgac
      661 gcatggagcg aatttcatgg agaatataat taagtgggtt taaatggctc taaaatcgct
      721 tctaagagtt ttttagcttg gaccaatgaa atacaccaaa aactaaataa aacgtcttaa
      781 atcgaaaaat acgagctctc agagcgactt tatttgtaaa tgttgcatat aagaaataat
      841 tacggatttt agacttttgt aggatatttt tgaaataaat atttatttct gttataattt
      901 gattgcaaat aagtgaacac gaaacacacg aaatccccag agaggtcgga ttctctgggg
      961 ctttttttgt gggctgagtc gccttaatta agttttactt cttgtttcgg ttattcaacc
     1021 agtaactgaa caaagcgctt aaaagcccaa caagaaggga gcaaataaag ttagtgaaca
     1081 cgaaacacac ctccttccag tcgcaagact gtcggatagg cgacaatcaa ttatacaata
     1141 aaaaagcaaa aataagccta agttttttat tgccttgggg ttgttagggc ttgccctgac
     1201 cgcctgtaag gcgctttaga acgaaggaca tagtttttat cgaatcttgt cttagaacgg
     1261 cttagacgag ctctcaggac gccacaaagg agtccctaat gaattatttt tggcgaagga
     1321 gcctaaaggc gactgctgca agtaaaatgt gagagcgtag cgatcactcc ttcttacagc
     1381 gaccataggg agctagattg gcagtttaat atcatgcgcg aacctgttta ttttaaaaag
     1441 tgggtgattt tttggcggga aattttgctc gcgcgcgcgc gtttatttta tttatttttt
     1501 aaagattttt tagaaccctt tttagggggc agttgagcct tactctccca acggatacag
     1561 aagggtacta acaacttttt atctgagtac taacaacttt ttatctgagt actaacaact
     1621 ttttatctga gtactaacaa ctttttatct gagtactaac aactttttat ctgagtacta
     1681 atatcctttt gtataataac aaccaaccta tttacgagtt ggttgttaaa ggttattatt
     1741 tatttgtaag gggggaagaa aggaatggat gaaaaaacgg aattaacagt caaatatcaa
     1801 aatgaattga atttagtacc gctgaaaaat ttcaatgcta agcagatgga tttatttttt
     1861 gcattatgcg ctcgtatgaa agatcgtggt ttgaaaaaag ttagattttc tttcgaggaa
     1921 ttaaaagagt taagtgatta taagatgact gctacaaaag cctttgtcgg tgatttagaa
     1981 aagctctata aagatatgct taatcttact taccgtactg aagatgagga ttctattcgc
     2041 tactttgttt tgtttactgg ttttgaaatc aataaaacaa aaaagtttgt tgaagtcagt
     2101 gttaatccgg acctagaata tattattaat ggtttaacag ctgaatttag tagatttgaa
     2161 ttatctgctt tcacgtcgtt gcgttctacg tatgcaaaaa ctctattccg actgcttatg
     2221 cagtaccgtt ctactggtta ttatgtagtt cgtattgaag agtttaggag cttaatggat
     2281 atcccagaat actatcaaat gggtaacatt gatcaaaaag tattaaatcc tgcattacga
     2341 gaactaaaaa aatacttcaa tgatcttaaa gtcacaaaaa taaaagcaaa aaagggcaat
     2401 aaaatcgcca aattagaatt tactttttca agcctaacgt cagatttgcc aa
//
LOCUS       DAZKCW010000144         2418 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000144 DAZKCW010000000
VERSION     DAZKCW010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.152"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(102..709)
                     /locus_tag="ACG84Z_002797"
                     /pseudo
     CDS             complement(102..709)
                     /locus_tag="ACG84Z_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            1232..1906
                     /locus_tag="ACG84Z_002798"
                     /pseudo
     CDS             1232..1906
                     /locus_tag="ACG84Z_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            1899..2060
                     /locus_tag="ACG84Z_002799"
     CDS             1899..2060
                     /locus_tag="ACG84Z_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163577.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
BASE COUNT          867 a          367 c          402 g          782 t
ORIGIN      
        1 ctatgaatat aaatagagtg tatcttcttt gataaatgtc agaaaaagtg tgacaaataa
       61 ccatcagtaa aattacttgt catactattg ataaggagta tttaattgaa gagaatgatt
      121 aggagaaagg atctccgtac tttttatagt aatcatagaa tccaagtttg tatagacgaa
      181 tctttttttc tcttatttct tctgtttcaa aatggactgc ttgaagaatc aagtctgtga
      241 attctatagg agctgttcca ttcgcagtaa tcaaattacg atctttcaca gcttgttgtt
      301 ctataaaatc ttctttattc tgataatttt ccgattctaa ccaaggaaat tgcgcatttc
      361 cggtgtgttt gtaaccttgc aataatccgc tctgagctaa ataatcaact gccccacaaa
      421 tagcagctac tggtacgtct gtttttaaca atttatcgat tatttgatat aaatgatgat
      481 tttttatgtc ccatgaattg ccaccgatca taataaaaag gtcaactttt tcaggtattt
      541 gttcgattaa gtaatcgatt tttgttttta atcctccaat ggaagtgacc tctgattgga
      601 tagaagcagt tttgttttgc catccctctt tttggtttag tgtgctagta atataagcac
      661 cttcccaatc ggcatattcc tctaatagaa acgtaatcgc agttttcatt ttcaagctct
      721 cctttactat ctatgacaag gacaacagtt ttaacataca gacattcatt aaatttggat
      781 agcgacagcg aaaacaacaa ttcttaagtt ttagacagag tatacagaca gtcaacttaa
      841 ttaaatacga actaaataaa aatgacaggt aatcattttt gtttaccagc attataacat
      901 tttgcataca tggatgacaa aagaaccaat tcccacttgc ttgagtacaa tcttaaaaga
      961 aactggaagg caaaaagtaa ttatagaaac gaaaaataaa tcatatcggg cactcagaca
     1021 tgaaaacaac cctagaaata tataactagt ccaatgaaaa aaaagcgaat gccgtagaaa
     1081 acaaggattc tgcgtacatt catatctcat tttgcgagca tatctgctat tactgtgact
     1141 aaatgttaat atggttaaaa tgaccgttat attttttata taaatatcgt ataattagta
     1201 tgaatataga agaaggaaag aaggtgcaat cttggaacct aaagacaagt atttagatta
     1261 cgctagggtc aataaagata aatttattga aacaatcatc aagggaaaaa tccctgatga
     1321 tgaaaaagat gcggtattca tggctggaag cccaggagca ggtaaaacag aggttgcact
     1381 aggtttagct taaaattatg acaaccatgt tgtgattgat gcggactatt ttagagcaca
     1441 atttccagaa tacaatggaa agaactcaag tgtttttcag aaagcttctt cttggttagt
     1501 tgaacaatca ttaaaatatg tactggaaca tggctattct ttcatactag aggatacttt
     1561 tgctatcctt agtgcagaga aaaatattat tcgagccctt aaaaataact ttcgcgttac
     1621 gattttctat gtttaccaag atcccaaagt tgcctgggat ttcactcgaa aacgtgaact
     1681 agctgaagga cgtcatgtgc caaaagaaat gtttatcaat gcgtttttta agtccagaga
     1741 gaatattgaa aaagtcaaaa atagacatcc tgaagtagtc cttcacataa tgattaagga
     1801 ttatcaaaac gacatttctg aagtgcatta tgcagcagat aatattcaat tagtactacc
     1861 aatacaatat acttcaaaag agttggagga ggaattacat gactgagaaa gaacaagtac
     1921 aacaaatcgt gaagaagtat aataaaagta tcgctgattt atcagaaaac gcctcagcga
     1981 aagaatttaa aacagtaatg aattacgtag cagatgaagc aaatcgtaag cagcgaaaac
     2041 tagttgggtt ggataaataa attttttaaa ccatatcctt gtaaagttga gttttttatt
     2101 ttaatgaatt aagactatta aatagataat tattgtaact taaaaaacac agctaaaaat
     2161 tagttgtgtt ttttattagg tttacttttc tggtataaaa ggaactagct actttttcaa
     2221 aatttctaaa tcattcaata tgtagcgctt actaaattat tcgccataaa attttataat
     2281 tggatcactc attgttttac ctaagtcata tttaagtaat aaccggtgtt tttacataag
     2341 aagacttcgg gtatttttta gtttgattag ctctgatata cctataaaga atatgctaag
     2401 gtaagaatag taaaaatt
//
LOCUS       DAZKCW010000145         2385 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000145 DAZKCW010000000
VERSION     DAZKCW010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.153"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            306..560
                     /locus_tag="ACG84Z_002800"
     CDS             306..560
                     /locus_tag="ACG84Z_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFP9163578.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            561..878
                     /locus_tag="ACG84Z_002801"
     CDS             561..878
                     /locus_tag="ACG84Z_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFP9163579.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1437..2372
                     /locus_tag="ACG84Z_002802"
     CDS             1437..2372
                     /locus_tag="ACG84Z_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163580.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          853 a          338 c          453 g          741 t
ORIGIN      
        1 aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc ataccgaacg
       61 gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt aaatggatgt
      121 taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta tatgttttca
      181 gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct taagaaacac
      241 cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa aaggagtgtg
      301 ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga gtgatccttc
      361 caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa ggcaacttat
      421 tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt gaagaaagtt
      481 tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa gctttcggaa
      541 aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa agttttcaga
      601 ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct ccagccagca
      661 taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat tttccaacta
      721 tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg atcgtgatcg
      781 gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata cttgtaggac
      841 gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga aaaagtcgct
      901 catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt cggttactcg
      961 aagattgata tataagactt agtacctttt tattttgctc catgttatgg ccgaaggtct
     1021 aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg gggatcgctt
     1081 ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc tctattccca
     1141 aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc aaaattgacg
     1201 taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt taaaagagga
     1261 agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa aatatacatc
     1321 cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa aggaatggga
     1381 taaaatatag gtacaataac tatttgatgc taaatataat taatggagga gagatagtga
     1441 acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt actactttca
     1501 aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa ggatacaagt
     1561 ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt ctttctgaga
     1621 gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt gatatatata
     1681 cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc agtgaatatc
     1741 tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta ctaccatatt
     1801 tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca ggtaatcaag
     1861 gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg atgggttacg
     1921 gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct gggcgttcat
     1981 tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag ttagaaaaca
     2041 tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt gaagttttga
     2101 aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata aaagcacatt
     2161 ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga gggaaaatca
     2221 atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta atgataacag
     2281 atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata aaacttgtta
     2341 ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagag
//
LOCUS       DAZKCW010000146         2353 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000146 DAZKCW010000000
VERSION     DAZKCW010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2353
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.154"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            57..2210
                     /locus_tag="ACG84Z_002803"
     CDS             57..2210
                     /locus_tag="ACG84Z_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFP9163581.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          806 a          416 c          528 g          603 t
ORIGIN      
        1 ttaagaagtt tttgggtaca atgaagcatg aatgtaaata ggcggaagga taggaaatga
       61 tgaaagattt tatgaaaaaa atattaaata cttcttggtt agaaaaaata agaaaaggtg
      121 cacaagaacc taagaacaaa acgtttcgcc ggtcccatgt tccttttcgc ttaaattttc
      181 tttttttcat tatatttacg ttatttgttg cgttgattgc tagattgggt tatttgcaga
      241 tcgtgaacgg cgaagagatg gaggcgcgag tgaagtctac ttctacgatt acggtccaag
      301 aaagtactcc tcgcggaatg atctacgact ccacaggaaa agctttagtt acgaataaag
      361 cgaatcaggc catcacatat acgagaggaa cacaagttac ggctaaagat ttgcttgaaa
      421 tcgcaacgaa gctgaactcg ctgatcgatg ttccggtaga tgaaaatctg acagatagag
      481 ataaaaaaga tttttggctg gctgatccca aacatttgaa agaagccaca aaaagacttt
      541 cggcaaaaga aaagcaatta gggaacagcg aacaatatag tgcgatggtc aataaagtca
      601 cagctgatga gattaattta aacgaggagc aattaaaaat tgctaccatc tttaaacgga
      661 tgaatagtgc atatgaatta aacactgtct atatcaaaaa ctctggtgtt actgatcaag
      721 agttagctgt tgtggcagaa cgcgcttctg aacttccagg agtttcgact ggcacagact
      781 ggacacgaga atataatgca gcaagttcac tgaaaagtat tcttggcagt gtgacgactg
      841 aaaagcaagg acttccagca gatgaagcag agaaatacct agcaaaaggt tattctcgga
      901 atgaccgtgt aggacaaagt tatttggaaa aacaatatga agatgtcctg caaggaacca
      961 aaacccaata tgaagtttcc cttgataatg aaggaaatgt ttcgaatcaa aaagaaatct
     1021 tctctgggga aaaaggttct aatttaatgt tatctatgaa tgcagaattc caatcaaaag
     1081 tagaagaaat tttgaaaagg aattatcaaa cattgatcaa caacggcaaa gcacagtatt
     1141 cgcctggtgc ttatgcagtg gctatgaatc ctcagacagg agaagtgcta gcaatgactg
     1201 gtttcagtca tgaacaaggt tccaaagaaa tcaccgagaa tgctttaggc acgattacta
     1261 gcgcctttga tccagggtct gtagtcaagg ctggtacttt gacagcaggc tgggcaagta
     1321 acgcgatcag cggaaatcaa gttttgattg atgagccgat tcgtctgcaa ggtgcttcag
     1381 aaaaaagctc tgtctttaat cgaagcggac aagttgctct tgatgcagtc aaagcatcgg
     1441 aattgtcttc taatacgtat atgatcaaag tggcgttaaa gatgttagga ctagactata
     1501 cacctggaat gggactacct agtttagatg aagaagctaa agcttatcag caattgagag
     1561 actctttcaa agagtttggt cttggtacaa cgactgggat cgatttgccg aatgaatctc
     1621 ctgggatctc acgttctgtt gattatatga agaagttcaa tgcggataat ggcaaagaat
     1681 ggtatgctcc aggtaacttt accgatttgg catttggaca gtttgacaca tatacaccaa
     1741 tccaattagc tcaatatgct tcaacagtcg ctaatggcgg gaaacgagta cagccgcacc
     1801 tagtcaaagc gatctatggc aatgacgaaa atggaaactt gggtgaagtg aagaaagaaa
     1861 ttggcacaac agtagaaaat acggtcaata tttctgcaga aaatatggcg atcctccgtg
     1921 aaggattcca ccaagttgtc catggtaccg atccttacac aacagccaaa ccattagcca
     1981 gtgcgaaaat ggacctttcc gcaaaaacag ggactgcaga aacggttgcg gaaggtcatc
     2041 cagatattgc gacagtcaat agtaatatcg tggcatacgg accaacagac aatccggaaa
     2101 ttgccatcag tgttgtcttg ccgaacttat tagacgaaca agaccacata aacttgacga
     2161 ttgctaaaga aataatggac gcgtattatg atatgttcat ggcaaaataa aaaagaggtc
     2221 gtgaaaaagc cgcttagttt cgagtatgaa gaaaaatttt gtgaaaatag cttctcacat
     2281 ttttgcttaa atttgacttc ataccgagaa actggctttt gaacaccgtt tactcggcaa
     2341 aaaaggttgt gac
//
LOCUS       DAZKCW010000147         2279 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000147 DAZKCW010000000
VERSION     DAZKCW010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.155"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..534
                     /locus_tag="ACG84Z_002804"
     CDS             <1..534
                     /locus_tag="ACG84Z_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163582.1"
                     /translation="ISFFKEYLEIINFRLKTKKESVIILVYFQGGNLMIKKLFLLSIL
                     TLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGILGRSNCKHRCS
                     NRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREVGDEPKLEYAF
                     SFAREDEDNPKTYDILA"
     gene            complement(595..960)
                     /locus_tag="ACG84Z_002805"
     CDS             complement(595..960)
                     /locus_tag="ACG84Z_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFP9163583.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1036..1281)
                     /locus_tag="ACG84Z_002806"
     CDS             complement(1036..1281)
                     /locus_tag="ACG84Z_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFP9163584.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1351..1605)
                     /locus_tag="ACG84Z_002807"
     CDS             complement(1351..1605)
                     /locus_tag="ACG84Z_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163585.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1769..2092)
                     /locus_tag="ACG84Z_002808"
     CDS             complement(1769..2092)
                     /locus_tag="ACG84Z_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163586.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
BASE COUNT          863 a          372 c          392 g          652 t
ORIGIN      
        1 ataagctttt ttaaagaata tttagaaatt attaattttc gtctgaaaac aaaaaaagaa
       61 agcgttatta ttttagtcta ttttcagggg gggaacctta tgataaaaaa actattttta
      121 ctatcaatat taacgctagc aatggcaggt tgttctgact ctggcttagc aactgaactg
      181 atcacaaaat caactgaagc cacgacagag gagttaaaat gtggaaacga tcacagtgac
      241 tacagaggct taaatcgacg atgcatggga atattaggca gaagcaattg taagcatcga
      301 tgtagtaatc gaagaaggtg tagaagaagc aacagaaaaa tcaaaagaaa gatcaaaaga
      361 agcaatctgt gctgtgcatc gtatacagac gtcgaagatg cggtactttt aaaccacgtc
      421 aggagatgtt catttatgtc tagggaagtt ggcgatgaac caaaactaga gtacgctttt
      481 agttttgcac gtgaggatga agataaccct aaaacttacg acattttagc ttgatctaag
      541 atggttaaag ctttttaatg aagtaagagg agatagaagg cttttctagt tatattaggt
      601 aagataaatt cctttttgct ccaaatttgc taaacattct gctagataaa cttcatcgtg
      661 ttccggataa atcggcacgt tgcgctctac agtaggtaaa tcaaaaaatg cttcgcatga
      721 tttgccacga tacataggat ttttccactc tggtgctggg ctgtaaccac gtttttccat
      781 ttcatccatg acaagctgat gatattggaa taatctataa ggagaatagt gaaaaacata
      841 atccacagta gcatgtttct ttccccagcc atttcctctt aatgcacagc attcccgatg
      901 ttgtcctaaa agctgttgac gaggaagctt tgaaatcaat ttttcatgcc ataatcgcat
      961 agaaatgtct cctttatata tagattgtta accttagacg ttaaatgaaa aaaccagcac
     1021 caaggctgga aaaaatcact tcagtttgct tgctgtttct gagcgaccaa ttaggtaatc
     1081 aacggaaata tcgtaaaagt cagcgatata gattaattca atgatgcttg gaatttcttc
     1141 tccttcttcg tacttacgat atttgaataa aggaatactt aacgcgctag aaacagctac
     1201 ttgagataaa gatcggccag ttcttaagaa attcagacga caacgtaaag tatccagtaa
     1261 aatagcttct tcgatactca tttaatcacc tttcattata gtagaatagt tataatgact
     1321 atagaaagct acacatgcaa tcaatagtac tcaatgtttt ttatttaaac gtatcaaata
     1381 aagaatgacg atcaataaag acaaaaccag tcctgataat tcttctataa aaacactatc
     1441 gggttcaaag tagttgtaat taaaaacttt ccacataaag tagatagccg gaagagtcaa
     1501 aatagctaaa taaaaccgtt ctttgttcca attcataaga taaacaatac ttgcgaccag
     1561 tgcgaccgca ggcacccaaa acaaaactct caccaacgta atcatgtaac ggactcctca
     1621 acgattcata taataaaaga taacatgtta ttgcatacat cacaaatgaa atgctaggaa
     1681 aataaaagaa gaatagatca atgaaaaatg aaaaagcaga acagttttct gctgataagc
     1741 aggaactgtt ccgctgaatg tgtcttatct atcgagaaaa aatcaatgga ttgatatcta
     1801 agtaattcaa tacatataaa aagaggacga tcgcattcac taaaaaggaa agaatgatga
     1861 tcccatagcg aatggaaaca tatttaacaa atacttttgt ttgaatacgg gcatatcttt
     1921 ttcctttata gctgagcatc atgacaagaa gcaaaagggt aatcacacct tgaaaaatca
     1981 ttccaataaa cagaattcct gaggtttgat aatttaattg gagaaaataa gctgctgccg
     2041 caactaaatc gaataaaatc gcaataaatg gcaaaataat cactcctaac attgagaata
     2101 aataaaagaa taacattttt tctaaaataa gcaaataaaa attaaagtaa caaaatagtt
     2161 atgacacaag taaaagaaat aagaataaca atattatttt acttatattt tgaaacttgt
     2221 gagagtttgt cattcgtgct atagttgaaa agtaacaaaa ataaatttta tttatgatg
//
LOCUS       DAZKCW010000148         2262 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000148 DAZKCW010000000
VERSION     DAZKCW010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.156"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(367..1659)
                     /locus_tag="ACG84Z_002809"
     CDS             complement(367..1659)
                     /locus_tag="ACG84Z_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFP9163587.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1933..2193)
                     /locus_tag="ACG84Z_002810"
     CDS             complement(1933..2193)
                     /locus_tag="ACG84Z_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163588.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          746 a          430 c          344 g          742 t
ORIGIN      
        1 tgtatgggct actctgtgat acttattagc cattaaacta ttttacccac atagcatata
       61 ttttgaaatc gttcattccg taaattcaac taaatatgcc taaaaaaata aaaaatctaa
      121 gatagaataa gatttattca gtcttagatg gatttatagc aactttttcg taacaacttt
      181 aaaaaatacg aaaagaaaga gctgttttac tctgactacg ttgctaaatt gtcgtttaat
      241 cattcattta aaccaaatct ttttttatag aattcgtttt aatcctcctg aatccaaaaa
      301 ctatgaaaac cgtaattaaa tagttaagag tttttaacca ccataattct ctcggctatt
      361 ttgaaatcag ataaattttg atcggacaca tagttgaata aacctaccgt tgttacggaa
      421 ggtaaatcgc atacttttca ttctagagga gaaggtctcg ttgatcatta actgattaag
      481 caccatagcc cagttttgaa ttcgaccacc tgaccacttc gcgtgtaatt ctttcgtgcg
      541 taaataaagt agttttagga gtgcattctc attagagaac gctccttttt ttgtgacttt
      601 tctgaagctg gagtggacac tttcaaccgc attggtagtg tacataattt ttcgaatggc
      661 actaccataa tcaaatagtt gttcaacatg tgcaaagttc cgtttccaga catctacagc
      721 accagaataa tgagaccacc gattttgaaa actgtcaaaa gcagcatgtg cagcgtttag
      781 agaagaagca ccgtagaact ttttcatatc tcggcagact tccttatagt ccttacttgg
      841 aatatagcgc aatgcatttc gaacaagatg aacaatacag cgctgaacaa ttaccgatgg
      901 aaagatcgct tttgcgcctt cttcgaggcc agaaacaccg tccatcgaaa tgaaaaagac
      961 atcttcgaca ccacgtgctt tcagttcatc aaatacttgc atccagcgat ttttagattc
     1021 tgtttgattt aaccataatc ctaaaatctc cttatttcct ttgagatcat agccaagaat
     1081 ggtgtataca gcatattctt tggcttcata attttctcgt aaagtaacat acatacaatc
     1141 aacgaataga aaggcataac actttgctag ggggcgggct tgccattctt ccaattcagg
     1201 aaggacagcg tcagtgatat ctgaaatcat ttcatgggaa atatcaaagc cataaatagc
     1261 ttcgacggtt gcggcaatat ctcgttgact cattcctcgt gcatacatgg aaagaacctt
     1321 cccttcgatg tcggagacat ctcgttttct cttaggaatt aactctggtt caaaggaagc
     1381 ttcccggtct ctaggaacat caatagctac ttcaccaaaa ctggttttaa gcgttttagt
     1441 tccatagcca tttcgacggt tatcgtgttc cttaggctct ttagaatggg catcataacc
     1501 taaatgatta ttcaattctc cttgaagcat tttttcaaaa aggggcccaa acacatcttt
     1561 caaagcatct tgcatgtcat cgacagattc aggttgatag gcattcagaa tggattcagc
     1621 taacttttcg gcatcaggat ttcttttctt tctagccatc gtgtaatcac ctcttgatct
     1681 tattgtagaa aaagaaaaac cgcgaagcaa ccacctgcct aggattaatg gttacttaca
     1741 cggtttatat tacactctca tcattaaaaa agtatctttc gatattacta aacaatgaaa
     1801 ttatctattt gaaatttaaa tctgataata tattgagtgt tccaatgagg gctttgatcc
     1861 tattatccat atctttttca gttttaatat tgatacacat tataagaaaa agaaactttt
     1921 ggttaattta tttcatccca gtgcaaaata taaaaaagta aaatagacca taggcaatag
     1981 attaacaatt aatataatac aagcaaatat tctattcatt gtatttctgc tttcaaaaag
     2041 ttctaatatt gaaagtataa ttccacaaat gcctataata agtatgggaa taagattaga
     2101 aaataacacc ccgagccaat ctgtgaaaat tactatattt actaatatcc ctattaacat
     2161 acctatcata tttattaaat caattttttt cattagatat ttctccttta ttaaatctga
     2221 agtacttata ttaaaataat tctaaactat ttacctcaaa aa
//
LOCUS       DAZKCW010000149         2238 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000149 DAZKCW010000000
VERSION     DAZKCW010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.157"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..587
                     /locus_tag="ACG84Z_002811"
     CDS             <1..587
                     /locus_tag="ACG84Z_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFP9163589.1"
                     /translation="FKTPEILNSSEITKFPVFIKPLNGSSSVNTFIVNNEKELLFFSE
                     YIDNPLIQEYILGEEYTIDVCLNFDSTPVSIVPRKRIATRGGEILKGQIIKDRELIET
                     TKKMLEKLNAIGHITIQCIKNEKGIFYLEINARYGGGAPISIKSGANSPEYIIKMIDS
                     KKNLRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            580..1275
                     /locus_tag="ACG84Z_002812"
     CDS             580..1275
                     /locus_tag="ACG84Z_002812"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFP9163590.1"
                     /translation="MIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIFPATFDEI
                     YRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLENADTLLTE
                     LRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPISYLLLLE
                     KFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFYQADKKIR
                     SLWEIKNFLGVIS"
     gene            1272..>2238
                     /locus_tag="ACG84Z_002813"
     CDS             1272..>2238
                     /locus_tag="ACG84Z_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFP9163591.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHL"
BASE COUNT          859 a          276 c          429 g          674 t
ORIGIN      
        1 gttttaaaac tcctgaaatt ttaaactctt ctgaaattac aaaatttcct gtatttataa
       61 aacctctgaa tggtagttca tctgttaaca catttattgt aaataatgaa aaagaattgt
      121 tgttttttag tgaatatata gataatcctc ttattcaaga gtatatttta ggtgaagaat
      181 atactataga tgtttgctta aactttgatt cgacaccagt aagtattgtt cctagaaaaa
      241 gaatagcaac tagaggtggg gaaatactga agggtcagat tattaaagat agagaactaa
      301 ttgagactac gaaaaagatg ttggaaaaat taaatgcaat cggacatatt actattcaat
      361 gtataaaaaa cgaaaaggga atattttatt tagaaataaa tgcaagatac ggtggaggag
      421 cccccattag cattaaatca ggagctaatt cccctgaata tattataaag atgatagatt
      481 caaaaaaaaa tttgagatac agagaaaatt atttagataa aatgatagca ctgagatatg
      541 atcaagcgat ttatttagat gaaaaaggaa atgtatataa tgattaaagc ggtgatcttt
      601 gatttagatg acactcttgt gtctgaatat gattatgtaa aaagtggata caaatgtgta
      661 gctagaagat tagcagtgca aaaaattttc ccggctactt ttgacgaaat atatagagtc
      721 cttttagatc tttttgctga agatagtaaa aatgtattta atcgtctata tgactatttt
      781 gaaattcctt atagtaaaaa agaaattaaa gaactggtaa atgtatatcg agaacacaaa
      841 ccagacataa attttttaga aaatgcagat actttattaa cggaattaag aagtagagga
      901 tacaagctgg ggattattac agatgggtat gctataaccc aacgaaacaa attggatgct
      961 ttgaaagtag actatttggt agattatatt tgtattactg acgaattagg ccgtgaattg
     1021 tggaaaccac accctatctc atatctttta ttgttagaaa agtttaattt aaaggcacaa
     1081 gagtgtatat atattggcga taatgagttg aaagatttta taactgccaa atcaatagga
     1141 atgcaaacaa ttaaaataga aagagtaaat ggtatttaca gagaaagcag tttgaagttc
     1201 aaaagatttt accaagctga taaaaaaata cgttcgttat gggagataaa aaattttttg
     1261 ggagtgattt catgaaaagt aaaagaattc tattagcttc tccacatatg agtgaagaag
     1321 gatatgaaaa agagtatgta aaagaagcat ttgatacaaa ttgggttgct cctttaggtg
     1381 cgaatgtgaa tggatttgag aaagaattag cagaatacgt gggagctagt catgctgccg
     1441 cattatcttc tggaacagca gctatacatt tagctttgaa agcggctggg gtcggtaaag
     1501 atgacatagt gatttgtcag tccttgacgt tctcagctac tgctaatcca attctctatc
     1561 aaggagctat acctgtattt gttgatagtg attacgaaac ttggaatatg aaacctgaac
     1621 atttgcgaac agcactagaa aaatatccta acacaaaggc tgtattagta gtacatttgt
     1681 acggtttatc agctaattta gacgaaatta ctaaaatatg caaagaatac gatgttactc
     1741 taattgaaga tgctgcagaa tcattaggaa caacatataa aggaaaatat actggaacat
     1801 ttggcgacta tggaatttat tcttttaatg gaaataagat aatcacaact tcaggtggcg
     1861 gaatgcttgt atccaatgac aaagaaaagg tggaaaaagt gagattttgg gctacgcaat
     1921 ctcgtgagaa ggcacgccat tatcaacaca atgaaattgg ctataattat cgaatgagca
     1981 atatcgttgc tggtatcggt cgaggacaat tgaaagtatt aaatgaaaga attgagaaaa
     2041 aacgatatat tcatagtttt tataaaaaag aattgtctaa attgtcaaat atacaattca
     2101 tgccagaaaa taattggaat gaaccgaatt attggttaag tgtcataaca ataaagggaa
     2161 taaatgcgaa tcatcttatt gatgagttag acaaaaataa tatagaagcc cgcccagtat
     2221 ggaaacctat gcatttac
//
LOCUS       DAZKCW010000150         2231 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000150 DAZKCW010000000
VERSION     DAZKCW010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.158"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            68..1681
                     /locus_tag="ACG84Z_002814"
     CDS             68..1681
                     /locus_tag="ACG84Z_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFP9163592.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNNYTSARILAGLGIKAILIEE"
BASE COUNT          696 a          397 c          444 g          694 t
ORIGIN      
        1 ccggcacaat tatttgctgt tttttaccat aacatagtac gatcaacgta gaaaaggaga
       61 tgtttttatg aaagttgttg tcattggcgg tgtagctggc ggtccttcat ttgccactcg
      121 tttccgtcga ttgaatgaag cgcacgaaat cattatctat gaacgcggag aaaatatttc
      181 ttatgcaagt tgtgctttgc cttattattt aggaggtgtg atcactgacc gtgactcgct
      241 gatcgaacgt acaccagaaa tattgaaaac aaaaaacaac atcgatgtct ttactaaaca
      301 cgaagtaaca gcaatcgatc cttctactaa gcgattaaca gttaaagacc tatccacaaa
      361 tgaagaaata aaaacagatt acgataagtt gatcatctct tctggtgcta gaccagatta
      421 tccggatatt cccggagttt ttgaagcaga aaacggcttt gtcctccgta gtgtgacgga
      481 tgcggatcga atcaaatcgt tccttgaaga aaaaaatcca caacatgtcg tcattcttgg
      541 tgcaggtgtt atgggtctgg aattagctga gaatttcaag catcgcggct tagacgtgac
      601 tttaatcgat caattgccac aagtcgcttt cccttatgat ccagaaattg ctaatttagt
      661 ttatgacaaa ttgctgaaag aaggattagc cgttcattta gaaacaagag ttactgagat
      721 ccgtgataaa ggtcgagaaa tagtattatc agatggctcc gtcctttctg ctgatatgct
      781 aatttttgct gttggtgttt ctccgaagaa tgaagtggtg aaagcaaccg gcatacaatt
      841 atcagataca ggtcagatca ttgttgatga ccagttacaa accaatctgc cggacatcta
      901 tgcgattggc gatattatcg aaacgactag tgtagtgact ggtcagccga tccaaagtat
      961 gctttccagt gcggccaatc gtcaaggaca tatgctggca gatattttaa atggtacgcc
     1021 tatgcgctat cgcggatata ttggtgcagg tgtcgcaaaa atctttgatc atacagcaag
     1081 ttatgcggga atgacagaac atgaattaaa agcatcaggc ataacaaatt ataaaactgt
     1141 ttttatcact ccctttgacc atgcctattt ctatccagaa gctacaagat taaatctaaa
     1201 gctgattttt gatgcagata gcggtcgtat tttaggtgga caagcatttg gagaaaaagg
     1261 tgtcgataaa cggatgggag aactttctgt agcaatcacc ggaaacttga cagtctttga
     1321 tttgcctgat ttggagttgc cttactctcc accgtattct actacccgtg acccgttgaa
     1381 tatagctggt tatgtcgcaa tcaatcaaat gacgaatatc gtagaaacga tcaaagcaag
     1441 tgatataccc gaaaacgatt tgaaagaagc gttcttttta gatatacgtg aacctaataa
     1501 agcaccttct ggcagtatct cggcaacaaa aaatattcca atgaatgagt tacgagatcg
     1561 aatcaatgaa atcccaaaag ataaaaaagt ttacattact ttcagaagag gattgaataa
     1621 ttatacttct gcccgaatct tggcaggttt gggtatcaaa gcgattttga ttgaagaata
     1681 aaaaaacgac cgcggtgggt agccgcggtc taggagttat ttttacttga ggagtaaaaa
     1741 tgaaaaagta tatagggttg ttggttggta tgtatataga atagaagata aatgtgaaga
     1801 aattgtgcat tatttcttca catttattag gttatagttt aagaaagttt aaacattgcg
     1861 caatttaatt attttagctg tttcttttca taaaaaaaca tgttgtgact ctgagacaaa
     1921 tcatagtcca tagtgatgtc tctagagtaa ctacgcctaa tattacgagg catcatatta
     1981 atctatcagc actagtacct aaactagcat ccctttcgaa tattttttct tatataataa
     2041 agtttgcttt cactcctcta atctcaccaa atcgactggc ttgcgttgtg tgatactagg
     2101 aactgattgg tttagaacga cttttctatt gtaatcatat ttttcgccat cctcgttgtc
     2161 ttctaatcct tcaatgaatg atccctaatg tgtgtattaa ataatttaat ttttttgttc
     2221 ctatttattt a
//
LOCUS       DAZKCW010000151         2220 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000151 DAZKCW010000000
VERSION     DAZKCW010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.159"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(51..1598)
                     /locus_tag="ACG84Z_002815"
     CDS             complement(51..1598)
                     /locus_tag="ACG84Z_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFP9163593.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACG84Z_002816"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACG84Z_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFP9163594.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          622 a          465 c          397 g          736 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
//
LOCUS       DAZKCW010000152         2179 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000152 DAZKCW010000000
VERSION     DAZKCW010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.160"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..914)
                     /locus_tag="ACG84Z_002817"
     CDS             complement(<1..914)
                     /locus_tag="ACG84Z_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFP9163595.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="ACG84Z_002818"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="ACG84Z_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFP9163596.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="ACG84Z_002819"
     CDS             2006..2176
                     /locus_tag="ACG84Z_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163597.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
BASE COUNT          741 a          384 c          416 g          638 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaaaaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaata
//
LOCUS       DAZKCW010000153         2123 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000153 DAZKCW010000000
VERSION     DAZKCW010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.161"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(76..501)
                     /locus_tag="ACG84Z_002820"
                     /pseudo
     CDS             complement(76..501)
                     /locus_tag="ACG84Z_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
     gene            complement(610..1641)
                     /locus_tag="ACG84Z_002821"
     CDS             complement(610..1641)
                     /locus_tag="ACG84Z_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9163598.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          651 a          344 c          366 g          762 t
ORIGIN      
        1 tatgcgtttt tttgttgatt taccaacatg tttagacatt ttcctctagg aaaaaattaa
       61 ctagcaccac gggttaggaa tctgttttga ttttgttcca tttgaaattt ctctcactcg
      121 cttttttgtc tcatcatcaa ataaaatgaa agggtcttct aaacgatcga taaatacttc
      181 cattgttgtt gttggtagat gataagaagt catgacaggc actgcaccaa ggtaagacac
      241 agaaacagct agaaggtatg tgtcaaaagc ggaactctta taaataataa ctttgtctcc
      301 ggatttcact ccaagatgag ccaattgata agcccgtttc aacacacttt cgcagcattt
      361 tttgtaagtt gtttcaagtc ctaattctgg gaaagctgaa agtggctcat caaagataat
      421 cggggtctcg gaaaagttag ctgcagcttc ttgaaaattc gtaaataagt tcaaagggga
      481 atacgttatg gtctccatca ttcacactcc attatctttt gttaagtaat atacaaattc
      541 aagataatcg taacataatc ctttatataa taacatagtt tattgtgaaa aaaagatcat
      601 acatttgttt tatatggaag aaacccgaac gaatgccgct aattcgtgat aagaaaaatc
      661 aaccatcttt tcccagatat cttgaaaaga atgggatgag aggtatcgat taccacataa
      721 ataatttacc gcgtcagcat catctaaata tagttctgca taataacgat atgtttttct
      781 gcatagttct ggcgatacgt ttttatatac tgtaattttg ctcaaaattt ggcgaatagt
      841 ccgaggagaa atttgctgat catgtgagga acgaaaaaca aaagaatttt cgtccgtatt
      901 ttgtgctgtt aacttaaaat agttctccag aaatggcatc gcttcttttg gtattggtac
      961 tttattcagt ctgttttctt ttctattcag attaagaatc tgcttggtca aagatacatc
     1021 tttacgttta agttctacta cttcatggat ctttaatccg caatacagaa gaatggcagt
     1081 aattgcaagg ttcctcggtc tattcttttc ttcaaagcta gcttctctgc ttgtttgaaa
     1141 gccttcaatc gggataaaca aatgctcaaa atctttgaaa agttctgcat cgatatatcg
     1201 cggagctgct ttggttgttt ccggtaaact tgtacccaaa agagaaatct cttcttcaat
     1261 cagtcctttt tgatacaaaa atcgtaaaaa atgatttaat gaatattgct tccttgaaat
     1321 cccgtaatag ctattttcaa acaattgctc cgtttcttgg ttcgctgtag tttggaacga
     1381 acgagtatgt cgatagattt tagctaagaa attctgataa tcttgttttt ctaaatggat
     1441 aatcagctga tcatccactt cttcagaaaa tacttttctc aaataatcag taaacagatg
     1501 aaaatctttt gcgtattcat agcgactgcc taatgaaagg gaagaacgat tttcttctaa
     1561 aaactgttga aagacggaag ggagcaagtg tgtacgttgc tttaactttt cttgcagttg
     1621 ttttctagtt ttgctgtcca ttacaaattc cctccaatag tgttcatttt ctatatttta
     1681 ccgcatttca tcaaatgaag atagacagtt tgtcttgatc ttaggaagca aatttttaac
     1741 taagtactag ctaaaagata tgaagtaaga agatacattt ttagttattt tattagtgca
     1801 gtcattcttt tgatctttta attgatttat cctcttttta gctatgtggt tacttcatga
     1861 gcaatgaaat ggatttggtt cgttctaatg gcaggaggct ctttctttta tttccgaaaa
     1921 attagaaaac attttttcag aatcgattgg ctctccattt attcaataat ggtttgtcta
     1981 acgatattgt tgggataatt cttaaagaag tattagaaat agttggtact tcattacttt
     2041 acatgaagat ttattctatg gtaggagcaa ttatattgag aattaatcct tttttatata
     2101 agttgtttgc ttattgatgg att
//
LOCUS       DAZKCW010000154         2098 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000154 DAZKCW010000000
VERSION     DAZKCW010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2098
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.162"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            710..1042
                     /gene="traE"
                     /locus_tag="ACG84Z_002822"
     CDS             710..1042
                     /gene="traE"
                     /locus_tag="ACG84Z_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFP9163599.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1661..2002
                     /locus_tag="ACG84Z_002823"
     CDS             1661..2002
                     /locus_tag="ACG84Z_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFP9163600.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT          739 a          278 c          435 g          646 t
ORIGIN      
        1 ataagttaaa atattatgat aaaaatcaca aacgtagcct tttacgtcat aagtgttaaa
       61 agaaataatt aatttcaaat atagaaaagg gaacgtatgt ttgcatactc cttttttttg
      121 agttataata atacgcgaag agagataatt tcattattta aacaagctaa aaatcttgat
      181 attacttctt ttcaggcaat acgaatatta ttcgcttaca ttttttgtat aaatttaatt
      241 gtctgctatg cttgtgatga attgattttc gttttgcact tttggatgat aaatttggac
      301 aattgaaaat acaaaaaaaa gaaaggcggt atgaactcgg aaggctggta accttcgtca
      361 gcgttcatac acggcattaa gatttggccc ttaatgcgtt aacctttcag tgttacggta
      421 ttacccgcaa tggatttagt ataacagata ttcaaaagtg ataccacttt ttttggctgt
      481 gttaaggtta aaaatacgtg atattacgat gaatctatgc ctaagcataa tgttataaaa
      541 atgtccgtgt ggctctttgc cgtataacga acgctgaaat tagagggaac gcatgtttgg
      601 atgcgttccc tcttttttgt ttgtcatgaa cgaaaatcaa ttctctattt ttgaaaaata
      661 acaagaaaaa cttgttaaaa atatttaaag aaattgggtg gtttatttta tgtcatatac
      721 aggaattttg agtctcaaag atatttgtca ctacggtaaa cggtgtaccg ctacagagaa
      781 aatcacgaag aaactatcaa ctggccaaag taaaaccgtt gtgcagtgta agaaatatat
      841 aatccagaaa gacaaagtct cagaggaaat gatttattac attgggaaac aaaagcaaat
      901 aattttaaaa gatcctatcc ccttaaaaga gctatatcca acaatcaaac atgtttatga
      961 ccaaaacggt gtactgattg gtcgaagaaa aaatggagtc ttgcgttgta ccgcaaaagg
     1021 gatggggcgt ttgatcggct gaattgatca ttctcataac ttgtatttta tcgtttttcg
     1081 cttgcttgaa aatattgtcg agacttctaa aggaacttag agtcactaga aaaataagga
     1141 gtagacttga tctatcaaca attcccttcg gggagtgacg gggtaggttt taacgattgg
     1201 taacgtaaaa aattggtcaa tcgagtaaat gcgcttgttt ggatagtggt gaaatgaatt
     1261 tgtgtaaata ataagcgcag agtaaacaag agggaattta gaagttagac aagttagaat
     1321 agcgtctaga ttaatcatga gcagctacta agggatctag actttgacgc aaactcatgg
     1381 aataaggagt aggtcttctc gtaatgggga ggacgcacaa gaaattgtgt cgtgtgctgc
     1441 agtacatgta gatacttgcg aggacgttga ttattggatc aatcgagcat ttaccgctgt
     1501 ctactagggt ttctcgtttc ggacgccata aacgagtcga aattttttat gtatttttaa
     1561 gtaaacgaaa aacgataaaa tatgaacaag tcctgaataa agtgaaaaaa ttaatataaa
     1621 gcatagagaa aatgaaattt acgtaatgga ggaatgacaa atgaaaaatt atgatccgaa
     1681 tatacgattg ggcacacata ctattaaggt ttctttccaa cgttgggatt acaaaggatt
     1741 tgtgacgttt agaaggggcg gaaattgtaa aggattagat gttttagcat tagacgagga
     1801 tgatttatac gatcaaacat tgactgataa tccaattgga ttcggcttgc tacctgaaga
     1861 tgatgaaggt aatgaatggt ttaaaatgac gcttatgaat gataatggag acgaattatc
     1921 tgttgaagat acttggtcat atttgagtga ttatattgtc agctttgaaa tcattgaatt
     1981 tgtagcggat aaagaagaat aaaaactgga ggaataaatt ttacagataa aggcttagaa
     2041 ggagtcacga cgattaataa aaaggtagta ttaccttagg cattgagtaa ggaattta
//
LOCUS       DAZKCW010000155         2048 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000155 DAZKCW010000000
VERSION     DAZKCW010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.163"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>2048
                     /gene="acm"
                     /locus_tag="ACG84Z_002824"
     CDS             <1..>2048
                     /gene="acm"
                     /locus_tag="ACG84Z_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFP9163601.1"
                     /translation="IPVHVYADAGRDISSNVTSLTVDPTNITDGGNIKVKFSFDEKKQ
                     NIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVGTLTVRKDSAQVVFNENIKNLD
                     SVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATVNVTKPASGSSSSVFYYKTGDM
                     LPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRLDPSTFEINQIHLGEQKVYRGE
                     EGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRKIMVSYKTIIENPEQINFENHS
                     EAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGELKIFKYINDTEIGIPNVTFEL
                     RRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVKEKEAPNWIDFDPLSSNELKFS
                     INENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPSIYFKLFRASTNNWEPVPDAET
                     KRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGNDYVPSGYQKIENGLVVTNENK
                     EVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQHKEVSEKDDWRYRFTNLPKYR
                     DGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNISIPGSHITPWKNFPEKTEREK
                     IRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITNKSKSILPKTSSKKSSFAVIIG
                     "
BASE COUNT          803 a          338 c          403 g          504 t
ORIGIN      
        1 attcctgttc atgtctatgc ggatgcaggc agagatatca gcagtaatgt cacttcgttg
       61 accgtggacc caacgaatat tacagatgga ggaaacataa aagtaaaatt ctcgtttgac
      121 gaaaaaaaac aaaatatcca accaggtgat tatctttgga tcaattggcc aagtgaagga
      181 aatattcgcg gtgaaggatt ccaaaaagaa atcccattaa tgattgaaaa taaaaatgtt
      241 ggaactttaa cggtcagaaa agattctgcg caggttgtgt ttaatgaaaa tattaaaaac
      301 ctagactcag tagaaggttg ggggcaattt gagatacagg ccagaaacgt aaccgatacc
      361 ggtgaagaaa atacgggacc attcaccgtg acgagcggtg ataaaacagc tactgtaaat
      421 gtgacaaagc cagcttctgg ttcttcttct agcgtttttt attataaaac aggagacatg
      481 ctacctgaag atactaagca cattcgatgg tttttgaata ttaacaataa cggcacttat
      541 gttgaacaac cagttaaaat cagtgatgaa atccaaagtg gacaaagatt agatccaagt
      601 acgtttgaaa ttaatcaaat acacttaggt gaacagaagg tttatagagg agaagaggga
      661 atccaacaat ttttacaaga tttccccagc gctacattta atttttcagt aactgataat
      721 tacattgaaa taactatacc aaaaaacttt gtcaatctta ggaaaataat ggtgagttat
      781 aagacgatca tagaaaaccc agaacaaata aattttgaga atcattcgga agcttggttt
      841 aaagaattta ataaacctgc tgttgatgga gaaagtttca atcatacagt taaaaatatt
      901 tcagcttctg gtggagtcaa cggtacagtt agaggcgaat tgaagatttt caaatatatc
      961 aatgacacag agattggtat cccaaatgtg actttcgaat taagacgagc agatgaacag
     1021 cctattcaag gacagtctag tatcctgttg acttcgaatg aacagggaga agctagtatc
     1081 aaaggcctgc aagtaggaga ctatgttgta aaagaaaaag aagcacccaa ttggattgat
     1141 tttgatccac taagttcaaa tgaactcaaa ttctccataa acgaaaatga tacagaggga
     1201 gtcagtttac ctatttataa caagaaaaag gttacgaaca tcacagcaac taaaatttgg
     1261 aacggtggaa ccactccaag accgagtatt tattttaaat tattcagagc aagtacaaac
     1321 aattgggaac cagttcctga tgcagaaaca aaacgattag acaatggaat aacttcagtg
     1381 acttgggaag atatccaaca gtatgatgat agtggaaacg aatatacgtt taaagtgcaa
     1441 gaagtagatc aaaacggaaa tgattatgtc ccttcaggtt atcaaaaaat tgaaaacggg
     1501 ctagtcgtta caaatgagaa taaagaagtc atttcagtct caggacaaaa aacatgggaa
     1561 gacaatgaga accaagacgg caaacgaccg acgacgatca cagtaaatct attagccgac
     1621 ggtcaaccga tccaacacaa agaagtaagt gaaaaagatg attggcgcta tcgtttcaca
     1681 aatctgccaa aatacagaga cgggcaagaa atcatctata ctgtaacgga agacaacgtg
     1741 cccgaataca gtacgacgat tgacgggtat aacatcaaaa acagttatac accggaaaaa
     1801 acaaatatat ctataccagg tagccatata acaccgtgga aaaattttcc agagaagaca
     1861 gagagagaga aaattagaaa tctattctct caaaaattgc aaatatttgc tcatacagga
     1921 gaatccagcg aacaaagaag caattatatt agtaagagag ctgtacctaa acagataaca
     1981 aataaatcaa aaagcattct tcctaaaaca agtagtaaaa aatctagttt tgctgtaatc
     2041 attggttt
//
LOCUS       DAZKCW010000156         2021 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000156 DAZKCW010000000
VERSION     DAZKCW010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.164"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            101..571
                     /locus_tag="ACG84Z_002825"
     CDS             101..571
                     /locus_tag="ACG84Z_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFP9163602.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            793..1896
                     /locus_tag="ACG84Z_002826"
     CDS             793..1896
                     /locus_tag="ACG84Z_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFP9163603.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          687 a          328 c          460 g          546 t
ORIGIN      
        1 agaatctctg aagaataaat cacgtgatcg tgacgataaa atacacttac gtcaggtgat
       61 aaaaaataca taagtagaaa actaagagga ggaacagaaa atgaaagaag ttcaattgat
      121 cagaaaaagc gaactatcag aaggtggttg caatgcatgc ggcgtagtag aagcaacaag
      181 ctatacatta aagcttggtg ccaacaaagc gataatctct gagttgacag taggcggtct
      241 tgtggacagt ctggcgcttg ctgaaggttt tattggagaa gatatttatg agatgttttc
      301 agaaatccgt cagttaaaaa aaggggaaaa ctgcatagag gttcatcatg agagcccgaa
      361 tgtgagattc aaacgtggtg ataatgagat gatcttcaat aatcatgtgt ccgatcacac
      421 cgagctatat ggaatcgtga atcaaatact aactgagctt tttggattgg gaccttatgc
      481 gttcaaggaa gaaaacggta atccaaaatt aaacgaagaa tggcaagaaa cgattgaaat
      541 acaaagaaac aacccgcact tatttcaata ggcatccaca gtatttcgta aaagggactt
      601 tgacacgact tttgtcaaaa tcccatcgtt ttttatctat ttgtgttcta aacatttctt
      661 tcagagtagt aacaactgga atgactgaaa tgtaaacaga ttatttgcct gtatcaatac
      721 ggaagagtaa tataaagtgt gtaaacgcta tcatattatt cattcaattt tttatagagg
      781 gaaggcattg aaatggaaaa aacgtatcaa gcaggtacaa atgaaggaat agtggatttt
      841 atcaatatgg aagatttaga aatagccgct tcacaagtga ttccagctgg tggttatggt
      901 tacatcagca gtggtgctgg cgacttattt acttatcaag aaaatgaacg ggcattcaat
      961 catcagctga ttattcctca tgtattaaga gatgtagaat tacccgatac aactacacat
     1021 tttgacaaag aaacgctgac tgcaccaatc atcatggcac cagttgctgc tcatggctta
     1081 gctcatgtga aggcggagaa agcttctgca aaaggtgtag cagattttgg gacgatctat
     1141 acagcaagtt cttacgcttc ttgtacatta gaagagataa gagaagcagg cggggagaaa
     1201 gcaccgcaat ggtttcaatt ttatatgagc aaagatgatg ggatcaattt ggatattctt
     1261 gaagtggcca agcgtaatgg agcaaaagca atcgtattga cagcggatgc aacagttggc
     1321 ggaaaccgtg aaacagaccg cagaaatggg tttaccttcc cactgccaat gccgatcgtt
     1381 caggcttatc aatcaggagt aggccaaacg atggatgctg tgtacaaatc ttccaaacag
     1441 aagcttagtc caaaagatgt agaatttatt gctgctcatt ctgatttgcc agtctatgtg
     1501 aaaggtgtcc agtcagaaga agatgtctat cgttcattag aatctggtgc tggcggaatc
     1561 tgggtatcta atcatggtgg ccgtcaacta gatggtggtc cagcagcgtt tgattcgttg
     1621 caatatgtgg cagaagcagt agataaacgt gtaccaatcg tgtttgacag cggtgtacga
     1681 cgcggacagc atgttttcaa agcaatcgca tcaggtgcag atcttgttgc tattggcaga
     1741 cccgttattt atggattgtc tttaggagga agtacaggag tccatcaagt gtttgatttc
     1801 tttaaaacag aattggaaat ggtcatgcaa ttagctggaa cacaaacagt agaagatatc
     1861 aaaaaaataa aattgcgtga gaatcgtttt atttaagaaa caaatgacga aaaaaatagg
     1921 agtgcggcag atgatgccgt actcctattt ttatagttca aggatgtcac taatagaata
     1981 atttgaaacg aaaaaataaa attgaaatat tttttcatac t
//
LOCUS       DAZKCW010000157         2002 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000157 DAZKCW010000000
VERSION     DAZKCW010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.165"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..377
                     /locus_tag="ACG84Z_002827"
     CDS             <1..377
                     /locus_tag="ACG84Z_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFP9163604.1"
                     /translation="NVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRR
                     FPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDD
                     WQKVMAAEVIATYLDGDLVYKK"
     gene            425..1825
                     /locus_tag="ACG84Z_002828"
     CDS             425..1825
                     /locus_tag="ACG84Z_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFP9163605.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
BASE COUNT          554 a          339 c          432 g          677 t
ORIGIN      
        1 aaaatgtttc cacagaggac ttctttaatt attgtcgatt agaggaaagt ggtgtaacag
       61 tcactagcgg tacagattta ccgctgttta ttactgatat tcctgaatcg attataagag
      121 cagtattccg tcgttttcct gaaggagaag aagtctggga gaaagaaaca agcttcacga
      181 caaccgagct gctgaaaagt tttacaagca acagcttcaa agtaaatggt ttatcggagt
      241 acggagaaat aaaagtaggg aaaagcgcca gcttagctgt tttcagcgag gacctctgta
      301 ctgatgactg gcaaaaagtg atggctgcgg aagttatcgc tacctatctt gatggtgact
      361 tagtttacaa gaaataatgc ttttcgatat aacgttataa aacgaattaa agagaggtta
      421 aaaaatggaa acaatgaaaa gaaaattcac cttcccacat agttatacat tgatttttat
      481 cttaattatt ttggctgcaa ttttaacttg gataattcct agtggtcagt ttgagacagt
      541 tgttgaaaac gtcgcaggta tggaaaaaac aacggttgtt ccgggaacct atcaccaaat
      601 cgataaggca gattatggac aaggtttttc ctctatacta atggcaccag ctgaagggat
      661 tatttcagct gttgaggttg ttgcttttgt tctcatcgtt ggtggtgcct tcgggattat
      721 cctaaaaacg ggagccatcg atcgagggct gtttacctta gcaaaagttc tgggagacaa
      781 ggggatctta gttattccga tgtcgatgat tctattcagc ttaggaggat caacctttgg
      841 catgagcgag gaagtcattc ccttatttgc ggtgtttatt tctctgatgt tttctcttgg
      901 ctatgattcc atgactgcga tcttgattct atttttaagt acacaagcgg gatatgttgg
      961 gtcgacgatt aatcccttca acgttttaat cgcacaggga gtagctggcg tttacggaaa
     1021 tcccctgctt tggtttcgga tgctatcctg gattgtcatt actgggattt caattgtttt
     1081 caccatgctt tatgctagca gagtcaaaaa gaatccactg tcctctattg tttatgagag
     1141 tgatttaaag gttaagcata agtttcaaaa ttttgacact gaaaaagagt tttcaacaca
     1201 agataaacta attatcgccg gttttatcgt aggtttagga atcatgattt ggggtatcat
     1261 ttccaaggga tggtatatgg ttgaaatttc tgcactattc ttaggattag gtctttttgc
     1321 tgggggcatc gctagatttt ctcaaaagga aattgctgaa gcttttgtcg aaggctgttc
     1381 agatttcgcc tatgctgctg taatcattgg gctagctaga ggagtcttgg taatcttgga
     1441 aggtggaatg attattgaca ctattctaaa cagcttggct aaccttttag gtggtcttcc
     1501 aaaattcctg ttcactacga ttctactcat ttctcaagta attgtttcct tttttgttcc
     1561 atcctcctca ggagctgcgg cattaacgat gccggttatg gcaccattgg gtgatctaat
     1621 gaatgtaagt cgtgatgttg ttgttctaag taaccagttt ggaaatggtt taatgaatat
     1681 tatctcccca actagtggtg tattactggc aggattagcc atcgcagaga ttaatttctc
     1741 taaatggttt aaggttggct tcaaaatatt tgccatctta acccttgttt ctgctgtttt
     1801 gttatacatt gctacactct tttagtctta atcatccatt aataggaggc aatagttatg
     1861 attaaaataa atcaattagc aggaatgaat atccactatt tattttattc tctcaaagaa
     1921 tttttcgctt atcaacagaa aattggtatt tcttctgttg aactttgggg aggtgctccg
     1981 cattttttca tagatgcttt ta
//
LOCUS       DAZKCW010000158         1979 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000158 DAZKCW010000000
VERSION     DAZKCW010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.166"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(346..528)
                     /locus_tag="ACG84Z_002829"
                     /pseudo
     CDS             complement(346..528)
                     /locus_tag="ACG84Z_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(728..1744)
                     /locus_tag="ACG84Z_002830"
     CDS             complement(728..1744)
                     /locus_tag="ACG84Z_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFP9163606.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          559 a          459 c          308 g          653 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaca ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat aatcgcttat
      661 cgtaaatcca cgtcactaaa cattgacgta aatttactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DAZKCW010000159         1934 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000159 DAZKCW010000000
VERSION     DAZKCW010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.167"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..246)
                     /locus_tag="ACG84Z_002831"
     CDS             complement(<1..246)
                     /locus_tag="ACG84Z_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFP9163607.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQE"
     gene            484..1653
                     /locus_tag="ACG84Z_002832"
     CDS             484..1653
                     /locus_tag="ACG84Z_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFP9163608.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          687 a          323 c          300 g          624 t
ORIGIN      
        1 ttcttgccat acctcctgaa tttgaccatc aggagtcgta atgaaaatag tatcattttc
       61 atctactaat tctcttaagt ttaaatattg tttactagat gtaaaattcg aagctgctaa
      121 tgacgagtct tcgcttttac tataaaatcc tgttacttgt attttatgtt cctggaaata
      181 cttcccgaat gaacaaccta ccttgccggc tccaataaaa ccaacgttca taattatcac
      241 ctccataaag aagtgagact acaagtccca ttcttacgat atgagcttaa aaataaaaat
      301 taaatcaaat atacagtatg tttttttcaa atatcatcca tagttaattt atcataatat
      361 cccatatttt aaaataaaag atagcgtaaa atattttgtg taaatagaaa tttagggtag
      421 aaaaaaaagt ccattctgta aaattaaagt taccacacag aaattttata ggaggacttt
      481 ctcatgacta aatttactat agaaattatg caaacactac tcaataaagg ggatttagat
      541 gaattatttc aggatcattt agagcgagcg attaattcac ttctacaagc agagctaact
      601 gcttttttag attacgaaaa atatgatcga aatggattca attcaggaaa ttcccgtaac
      661 gggaattatt cacgtacatt taaaacagaa tatggcgagt tgaatttaac tattcctaga
      721 gatcggaatg gcgaattttc tcaacaaaca ctaccagcat ataagcgaac caatgattca
      781 ttagaaacga ccattatcca attatttcaa aaaggcatta ctatggctga aatctccaaa
      841 ttaattgaaa aaatgtatgg tcaccactat acgccacaaa caatctccaa catgagtaaa
      901 ttggtggctg aagatgtttt agcttttaaa gaaagaacgt tagaagccaa ttattccgtt
      961 atatttatgg atgcgacgca tatccctgtg aagcgacaga ctgtttcgaa ggaagcagtg
     1021 tatattacga ttggtattcg tttggatgga accaaagaag ttcttgggtt tactattgcc
     1081 ccaactgagt ctgcttatat ttggaaagaa gttcttcaag atcttagaaa acgtgggtta
     1141 gaagaagttt tattagtagt gacagacgga ttaagctgta ttgaagaaag tatccatagt
     1201 gtgtatccga atgcccaatt tcaacaatgt tgtgtgcatg tatctagaaa tatcgctcat
     1261 aaagttcgtg ttcgaggtcg aaaagaaatt tgtgaggatt tcaaattggt ttaccaagcg
     1321 aattcaaaag aagaggcatt ggatcacatc gactttatga ctaggaaatg gaaaaagcag
     1381 tatccaagag tcgtcaattt actcttgaat cctgccctat taacctttta taatttccct
     1441 cacgccatca gacgaacaat ttattcgacg aacctgattg aaggctttaa taagcagcta
     1501 aaacgatata ctcgaagaaa agaacaattc cctaatgaag aatctctaga gagattcttc
     1561 atttctcaat ttaatcaata taaccaaaaa tttttaggta gaattcacaa gggatttaaa
     1621 gaaattcagg atacattaga gtcgatgatt taactgtaat taacagaatg gattttccat
     1681 ttacatataa ttcttgacgc taccataatc taaataacca tcatattcat ctactactta
     1741 tataattgag ttttattaaa ctttttaagt ttctattcta tcaaatattt aaacaatctc
     1801 tgcatccgaa aagactacct cgtatagttt tactaacaat atttttatta gcgtgttcaa
     1861 atcctgattt cttgtatcaa ttattttctg ttcactttca ataagaaaaa agtctttact
     1921 tccatggata ataa
//
LOCUS       DAZKCW010000160         1925 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000160 DAZKCW010000000
VERSION     DAZKCW010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.168"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            45..1889
                     /locus_tag="ACG84Z_002833"
     CDS             45..1889
                     /locus_tag="ACG84Z_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163609.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT          631 a          354 c          319 g          621 t
ORIGIN      
        1 aaacgtttac cctaacatta caagttttag aaaggaatac ctttatgtct ttttttaata
       61 acatatataa taaaaaagaa tctttttatt tacgtataaa gtggagcata atcattatat
      121 tatcattgtt atttttaaca ggaattgctt atttctttta ttttattttt tctcctgcgg
      181 acagcaatca aatgaaagaa ataaaagatt cgtgggtttt ctatacaaaa gatgatcctg
      241 attttaagtt tgacagcaag tacactcgta cgattcctac cgtggataaa gacgaaacat
      301 tcattatgga aacgacactt gaaaaaccgt tggacgaagc aaatttacta atcaaaggaa
      361 accatcaatg gattactgta tatctaggcg aaaagatttt ataccaacgg aaagattatc
      421 aggaagaaag caatcccgga ctctcattgg ctgtgataga tttaccagca aattatatcg
      481 gaaaaaaatt gacccttaca gtctcatctc cttatcagaa ctatgctgga ctgccaccga
      541 aagtttatct aggaacaact ggaccattga ttagttttat ttattcacaa tcagtgccgc
      601 aagtattgac gatgataatc gctgttttta tcgctatagg gacctttttc tatacgatct
      661 acttgatgta taaacaaaaa cgtcttgaat actcacttat tctcttaagt tgctttgctt
      721 tggcattagg atttgaagct gtatcagaag atattttaag tggtattctt tttgaaccat
      781 tcgttcattc ttttttatct catttattta ttatcttaac gtcagctttc atcatctgct
      841 actattggag ccgaatgttt tactataaaa aatggtacgg aattttttgt acgttccaac
      901 ttttgatttt tatcggcgtt ctgctttatg caacttttac tcctgcagaa cttcctgaat
      961 taatgccgat tgctaatatt gctagtgtta taagcacttt agtcacttca cttgcatgca
     1021 ttggcgaagc atataagaat aaccgttttt atgtagcttg tacaccttgg atcgtcttgg
     1081 tagccattat ccattgcttg atttacatcc aaacggcatt aggtatctat caaacaacga
     1141 tcaattggtc tacgatttta tatattatca ttctaatcgt tattatcagc tacaatctaa
     1201 tcgatcacat cttaaatacc gacaaagatc ggagacaagt agatttctta aaaatcaaaa
     1261 atgatttgtt ggagcaacat tatgagcagc ttcgacagca tatccaagaa gtaaatacac
     1321 ttcgcctgga atttgtccaa gagatggaga atctgcaaga tttaatgcat acggaccaaa
     1381 caaaagctaa aaactatgtg gaaaagatat tagaagaagc aaaaaatttc gaaatgctgt
     1441 gttctttttg caaccaccag gtgacaaatc ttatcttagc gcgttaccag aagttagctg
     1501 ccaaacggaa tattcagata accttccaag cagatcttcc cgaagaactt cctatcaacg
     1561 atgacgatct ggctcaactt ttgatccacg ctttagagca ttcctttaga gaaactcatg
     1621 ccatcgaaaa tccactgtat cgaaaaattt atttgtcgat acacgaacaa gaggaacatt
     1681 tcgtcatttg ttgcgaacat agtgcacatt acgatacaaa cctatttagt cgaggcatca
     1741 cagaagaatt agatgatcag gaacgttttg acttaatgat gatgaaagac gtagcggatc
     1801 gttacacagg aacactaacg caggaaaaag atactttcat tgatcggatc actgttcaac
     1861 tctctcgaaa ttacccgaat cctgtataaa aaatagcgga atccatatat gtggattccg
     1921 ctatt
//
LOCUS       DAZKCW010000161         1919 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000161 DAZKCW010000000
VERSION     DAZKCW010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.169"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            273..839
                     /gene="amaP"
                     /locus_tag="ACG84Z_002834"
     CDS             273..839
                     /gene="amaP"
                     /locus_tag="ACG84Z_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFP9163610.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            852..1040
                     /locus_tag="ACG84Z_002835"
     CDS             852..1040
                     /locus_tag="ACG84Z_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFP9163611.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1053..1610
                     /locus_tag="ACG84Z_002836"
     CDS             1053..1610
                     /locus_tag="ACG84Z_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFP9163612.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1642..1884
                     /locus_tag="ACG84Z_002837"
     CDS             1642..1884
                     /locus_tag="ACG84Z_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFP9163613.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          706 a          295 c          395 g          523 t
ORIGIN      
        1 aataaataga atcttgtaat aataactgag cataatcttt gcaattttta atcttgaata
       61 atatccttta agtatagcca gcaatcaaaa gtaaatagag aataagtaag caattgttat
      121 ttcagtatca gactggcaat aaaacgccgt tatgatccag caatgtttgg tagcgcttta
      181 tttactgatg ctatgctaac tgttcgctat ctatactgtg attgtcggta gagttattta
      241 cagggtaaaa ataagtttat aggaggtgga aaatgaataa ggggttaaaa ataatcggtg
      301 ttatcatgag tttactgcta ctttcagtat ttctagcgat tgcgttgatc aatgcgccgt
      361 atattatgcc tgaacaattg gaacgatttc gcttctttac tttaacgaat tactacatgc
      421 aacaatatat tttctgggca gctgtagtat ttgccgttct tgctattatc atcttgctag
      481 tcgttctttt ctatccaaag tcaagaggaa ctttcgttat gaaacgggaa gatggcaaac
      541 taacaatcga caaaaaagcg atcgaagggt tggtacgttc ccatttacac gaagaagagt
      601 tcattcattc acctaaagta cggatacgtt caacgaaaaa tcgaatccat atccatgtca
      661 acggagactt gaaacgaact tcttcattag tagggaaaac aggtgtattg atgcaagata
      721 tcgaagaaga agtaactaaa gtactcggaa caaaagaaac ggtcaaagtg gcagtcacat
      781 acagcggtta tgaagaacaa gaagatacaa gagactacaa gcactctcga gtggaatagg
      841 agggccaaat aatgaaagaa ctattttcag catacaagct ccctattatc tttgggggtc
      901 ttggactact gctagctgtt ttatggttaa cgattggatt tttcaagaca ttgttgatca
      961 taatcatgac agcaattggc gcaggaatcg gtttttattt gaaacagtca ggaatagttg
     1021 atcaattttt taaatcatag gaggaaacaa agatggaaaa caaaaacatg aatacaacaa
     1081 atggatcagt tttggcaaat gaaaaaggag aaaaccgcat gatgaatggt gaattgactt
     1141 atgaagacaa agtcatccaa aaaatcatcg gttatgcatt gaaagatgta gatggtctat
     1201 tgacattaga tggcggattt ttctcaaata tggctgaaaa attagtcaac acagataacg
     1261 taacagcagg tatcaataca gaagtaggta agaaacaagt agctgtggat ctagatgtga
     1321 tcgtagaata cggtaaagac atcgaagata tttacaacca aatcaaagaa ttgatcagta
     1381 ctgaagtaaa caatatgaca catttagatg ttatcgaagt gaatgtgaat gttgcagaca
     1441 tcaaaacaca agaagaatac caaaaagatc aagaaacagt acaagacaaa gtaacagaag
     1501 cagcaaaatc cacaggacaa tttgcttcac gccaaacaga taaagcaaaa tctgctgtag
     1561 gcaaaggtgc acaaaaagtc aaagaaaata acgaaccacg tgtacaataa gaagtaagaa
     1621 gtcagttagg aggaatttaa aatgggattt atttgggcat taatcgtcgg cggtatcatt
     1681 ggagcaattg caggagcaat cacgaataaa ggatcatcaa tggggatcat cgcaaacatc
     1741 attgctggtt tagtaggttc agcaattgga caagctttac taggaacttg gggaccaaca
     1801 attgcaggaa tggctatcat tccatcattg atcggtgcaa tcattttagt attagtcgtt
     1861 tcattctttg cacgtaaatt ataagcaaat tgaagaaaaa cttatgttga aatgaagaa
//
LOCUS       DAZKCW010000162         1731 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000162 DAZKCW010000000
VERSION     DAZKCW010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.170"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1002)
                     /locus_tag="ACG84Z_002838"
     CDS             complement(<1..1002)
                     /locus_tag="ACG84Z_002838"
                     /inference="COORDINATES: protein motif:HMM:NF016901.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163614.1"
                     /translation="MTLPDFPIYNIYLHFYKASYNYHLIDFMYKYPRSVLKDFAKEQF
                     TSVSTVFRYAKLLIPYFRRYHITFHPFQLELNASEANIRSFFYYFYWNSTRESSDKWP
                     FHIEQKEIEKYIVAFEGIYDITLTIFQKRVFSFWLAINIERSSFRKVRVDNEYKSVIS
                     DDPHFNLLKKWSKQINLSFNSDELCFLYRIIYSFGVIDGNAIYENSHAYAHQRQNTCS
                     YRAVENLEKVLQSMFRFSLDIKDPELIFNFIAFHERSYLFYGNPDLFFNRSYIEEMKE
                     EEPRTYHIMEKLKKELQANADLDVSKKLENWAQLFLDYYYVLDYYDLFLTNVKPIKIL
                     "
     gene            complement(1044..>1731)
                     /locus_tag="ACG84Z_002839"
     CDS             complement(1044..>1731)
                     /locus_tag="ACG84Z_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HFP9163615.1"
                     /translation="TYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWN
                     ELLQDINSRGVQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDR
                     KEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYDFPPSIR
                     RTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQV
                     TDTLVSMFTE"
BASE COUNT          580 a          276 c          261 g          614 t
ORIGIN      
        1 taaaatctta atcggtttaa catttgttaa aaataaatca taataatcta acacataata
       61 ataatccaaa aataattgtg cccagttttc taatttcttt gatacatcca aatccgcatt
      121 tgcttgtaat tcttttttga gtttttccat tatgtgataa gttcgaggtt cttcttcttt
      181 catttcttcg atatacgaac gattaaaaaa aagatctgga ttaccataaa atagataact
      241 tctttcatga aatgcaataa aattgaatat gagttctgga tcctttatat ctaaagaaaa
      301 acggaacatg ctttgtaaaa ctttctccaa attctcaact gctcgataag aacaagtatt
      361 ttgtcgctga tgtgcatatg catgactatt ttcatatatt gcatttccat caattactcc
      421 aaaagaataa attattcgat aaaggaaaca cagttcatcg ctgttaaaag aaagattgat
      481 ttgttttgac cacttcttca aaagattaaa atgcggatca tctgagataa ctgatttata
      541 ttcattatct actcgtactt ttctaaatga acttctttct atattaatgg ctaaccaaaa
      601 agaaaataca cgtttttgaa aaatagttaa cgtaatatca taaatcccct caaaagcaac
      661 tatatacttc tctatttcct tttgttcgat atgaaatggc cacttatcac tactttcacg
      721 tgtagaattc caatagaaat aataaaaaaa gctacgaatg tttgcctctg atgcattcaa
      781 ttctaactga aatggatgaa atgttatatg ataacgccta aaatatggaa ttaagagctt
      841 cgcatatctg aaaacagtag atacactagt aaattgctct ttagcaaaat cttttagaac
      901 acttctagga tatttataca taaaatcaat caaatgataa ttataagaag ctttataaaa
      961 atgaagataa atattataaa taggaaaatc tgggagcgtc aataattttg tgtaaataaa
     1021 ttgtcctcct gcaaaataat tagttactca gtaaacattg aaactaatgt atcggttacc
     1081 tgttgaaaac ctttatggct tctgtttaga aatttttgat tgtatgtatc aaaaatgctg
     1141 actagaaagc gttctagtga ttcttcattt tgaaactgct cttttctacg gctgtatctt
     1201 ttaatttgct tattgaaaga ctcgattaga ttggttgagt aaatggttct acgaatgcta
     1261 ggtggaaaat cataaaaagt taataagtct tggttttcta tgagtgactg cgtcacttta
     1321 ggatagtttt tcttccattt ctcaatcatg ccggataaga aggtattcgc ttcttctttt
     1381 gagttagctt gataaacagc cttaaagtca tcacagattt cttttcggtc tttgacacgt
     1441 actttatgag cgatgttacg agatacatgg atacaacaat gctgatattt tgctttagga
     1501 taaatttgat ggatagtatc tttcatgcct tttaagccgt ccgtaataaa aagcaagact
     1561 tcttgaactc ctctggagtt aatatcctgt agcagctcat tccaaacgta tgttgattca
     1621 gttggagcaa tcgcataact cagtacttct ttagtgccgt cttctcgtat accaatggca
     1681 atataaatcg cttctttgga tacggtttga cgttttagtg gaatgtaagt a
//
LOCUS       DAZKCW010000163         1707 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000163 DAZKCW010000000
VERSION     DAZKCW010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.171"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     regulatory      86..252
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            426..1532
                     /locus_tag="ACG84Z_002840"
     CDS             426..1532
                     /locus_tag="ACG84Z_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFP9163616.1"
                     /translation="MIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLSWSVIFLAR
                     SVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQFQPSELANL
                     FLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIAWVIFWAAA
                     VPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDSFIDSHGAG
                     YQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIGALCVLFLL
                     FSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGVPLPFVSYG
                     GTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
BASE COUNT          489 a          278 c          361 g          579 t
ORIGIN      
        1 gattgttaaa tttcactatt tcatttcaaa ttccattgcc taatcattag gaaaagtcta
       61 tcatgaactc gtaaatagaa tatagtaata accttgttag gtgaggctcc tatacaaaca
      121 taggctgttg cccagaaacg tcgaaagtcg ccaatgggta aaacagaaac tgttggatta
      181 aggctttttc caatagctaa gaatgttttc tttacgttgt atagtgctaa aactcggacg
      241 atgagatgat gctaggtcag aattcttgtt cgaaaaggtt tctgaccttt tctttatatt
      301 tttgtgactg acttatttga tgagacaaac tcgctcctca cctgacaagt ggattgctgt
      361 gtgaggagga gatgcggtga aaaaagatcg attggtggat tttgggtcct tatttgactt
      421 tgtccatgat cggtctttta gaagtataca gtgccagttc ttatcgttta ttgcaagccg
      481 atgaaaatac aaaaagtcta ttattgcgtc aactaatttt catatttttg agttggagcg
      541 tgatcttctt agctcgttca gtcaaactac actatttact tcaccctaaa atagcaggat
      601 acggtttagc cttatcgatt ttctttttag tattagtaag aatagggata ttcggtgtca
      661 ctgtcaacgg cgcacaacgt tggatctctc tgtttggcat tcaattccag ccttctgaac
      721 tggcaaatct ttttttgatt ttttatttaa gctggttttt tcgtgacgga aatagtagcc
      781 caaaagatct aaaaaaacca ttcctgatta cagtaggtat aacttttctg attttatttc
      841 agccaaagat tgctggagca ttgatgatcc tttcgattgc gtgggtcata ttttgggcag
      901 cggcggttcc atttaaaaaa gggatctatc taatcgttac tttttctgca ttgctgattg
      961 gagcagcagg cggggtatta tatttaggaa ataaaggttg gcttccacag atgtttaatc
     1021 atgcttatga aaggatcgcg actttaagag attcttttat cgatagtcat ggtgcgggct
     1081 atcaaatgac ccattcgttt tatgcactat ataatggtgg catatttggg cggggattag
     1141 gaaatagtat cacaaaaaaa gggtatcttc cagagacaga aacagatttt attttttcga
     1201 ttattacaga agagcttggg ctaatcggtg cattgtgtgt gcttttctta ttgttctcat
     1261 tatgcatgag aatcttttgt ttaagcagtc gctgtaaaaa tcagcaagct ggattgtttc
     1321 ttttaggatt cggaactttg ctattcgttc agacgataat gaacgtggga agtatcgcgg
     1381 ggctgatgcc aatgactggt gtgccattgc catttgttag ctacggagga acaagttatc
     1441 tgatcctttc tttaggaatc ggaatcacgt tgaatatttc ttcaaagata caggccgaag
     1501 agttggcgct ctatcgacct gaaaaacaat aaagagaaac tgagaaactc tcagtttgaa
     1561 ttatcataaa gtacaatctt ttatttttca agcgagaggt tcttttagaa agaggaattc
     1621 gcaatgaaag tatctcaaaa aatcatatta tacccgtggt gctagttaat tttttcctag
     1681 aggaaaatgt ctaaacatgt tggtaaa
//
LOCUS       DAZKCW010000164         1664 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000164 DAZKCW010000000
VERSION     DAZKCW010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.172"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..505
                     /locus_tag="ACG84Z_002841"
     CDS             131..505
                     /locus_tag="ACG84Z_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFP9163617.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ACG84Z_002842"
     CDS             complement(619..1248)
                     /locus_tag="ACG84Z_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFP9163618.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ACG84Z_002843"
     tRNA            complement(1382..1454)
                     /locus_tag="ACG84Z_002843"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          557 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt actt
//
LOCUS       DAZKCW010000165         1655 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000165 DAZKCW010000000
VERSION     DAZKCW010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.173"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..334)
                     /locus_tag="ACG84Z_002844"
                     /pseudo
     CDS             complement(1..334)
                     /locus_tag="ACG84Z_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            609..1151
                     /locus_tag="ACG84Z_002845"
     CDS             609..1151
                     /locus_tag="ACG84Z_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163619.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            1307..>1655
                     /locus_tag="ACG84Z_002846"
     CDS             1307..>1655
                     /locus_tag="ACG84Z_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFP9163620.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          603 a          220 c          315 g          517 t
ORIGIN      
        1 ttgcacatcg ctgatatgga atatttatgc ttgttggcat caattacttg tcttttcgtc
       61 cgaatatcag cgccgcttgc tttaaaatat cattctccat ttcgagttgc ttatttttct
      121 ttcttagtgc gatcaattct gcttgttctg gtgttaagtt gtctctttct ttgaatgagc
      181 ccgttgattg tgcttgcttc atccatttat cgaaagaaga aggcgtaagc tcatactctc
      241 gaataatttc tgcgcgaggc ttaccagcga gatagagatc gacgatttgt tgtttgaatt
      301 cttttgaata ggttcttcgt tgacgtcttg acatgaaaaa tcctccagtg tgttttttat
      361 tattctacac accttatttt ttctgtctag tctagtgtag ccgattcaaa ttgatgaagc
      421 agatcccaaa gggctgcttc atcaattttt tcgtaagtgt ccgtacactt actgtgcttg
      481 ctcatatatt aatcgatcat atactaatcg tgtaagaaca actttaagca taatacttat
      541 attgttatac catagtttgg aaaaataaaa aattatattt catcaacgtt tcataaaagg
      601 tgtgtagaat gttattgaaa gtagctataa aatgctattg tgtaaaaaat aaaggaggaa
      661 taatttatga aaaaatagta ccaagaggag catgcctatt acttgcatta tgtttgagct
      721 taagcgcagt tgggtgtcaa aaaagtaatg aaaacaataa aataaaagaa ggacaatcca
      781 taagttctga agaggaaggc atgtcaatta atgcaaatgg caaaaatgaa acttttaagc
      841 catcagatta tacattggag gcaaagaaag aatatgttta tgaatattta gggcttaaat
      901 ttaaactctc agacaaattt agaaattata tagctgataa aaagatagcg atgttagatg
      961 atcaaagtcc tatagataaa gaactaaagt atgctatttt gacatttgag aaaatgacag
     1021 aagaacaaaa gaatgcagtt atagaaaaga tgggcgatgg atataaaaat tggcaaaatg
     1081 agcttgaaag aattgggact attggtatat ttgaaaaaaa tacatcagaa gaaaaaaatc
     1141 taaaattata aaatgtgata ctcatactaa aataggagtt tcaagtgatg gaaaatacga
     1201 ttgctattta agcacaaata gcggagctga aagtaatctt ctggatgaat taaaaagaac
     1261 tgagattcaa attatagata aaaaagaacg tcctaaaaat ggttttgtgc tatcagaaaa
     1321 aactgattta gaaaatacag aagcatttaa caaagaatcg gttaaagatt tacgtaaact
     1381 accaacaaag gacataaatg gcaaggattt tacaagtaaa gattttgaga agtatgatct
     1441 tactatggta aatgtatttg caacttggtg tacagcttgt gtaaaggaaa ttcctgattt
     1501 ggttgaggtt cagaatgaaa tgaaaagcaa gggtgtaaat atcgttggag ttgttacaga
     1561 tcctgttgat gataacggtg aaaacaagga agcaattgaa aagtcaaagt taatacatga
     1621 aaagacaaag gcttcatatc ctttcttaat gccag
//
LOCUS       DAZKCW010000166         1620 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000166 DAZKCW010000000
VERSION     DAZKCW010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.174"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            531..1571
                     /locus_tag="ACG84Z_002847"
     CDS             531..1571
                     /locus_tag="ACG84Z_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFP9163621.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT          628 a          208 c          252 g          532 t
ORIGIN      
        1 ttaaagtaat ttttttcaga ttaacacagt agtatcttat taaataagtt aattttaatg
       61 gtagtacata attattatat atatctgaca ttggtagtac ttattgtatt ttttagtagt
      121 atataatcta ttgttttcta gcctaaagcc ttgtcttata agaataatat aatatatact
      181 actgaaataa ggtagtatat attactagta atggtagtat gttttatatg cataaggtag
      241 ttcttaattt attttttgtt ttgacactgg tagtacttaa ttatctttaa ttttaaaact
      301 aaattttatt catacgtttt tctggtagta tttaattata aataatattt atttaaagta
      361 gttcttaatg actttaaagg tagtacataa ttcattttat ttctgatttt aggtagtatt
      421 taattaaaaa acagttttaa tgcgtttgca ttttttattt atctttgcta ttttcgaaaa
      481 gagtaggtaa ttttacataa ataaaacaac gtgaaagtag aggatctaca atgactgatt
      541 ttaaattttt taaggcggat agagtttaca acgaattatt ttatcaattt ccaaaagtct
      601 ttattgtttc tgacgaatac aaaaaaatga aagattcaac taagattgcc tatatgcttt
      661 taaaagcaag attagagatc gcaatcagca aacggcaaat cgatgaagaa ggtaatgttt
      721 attttactta tacgacaaat gaactatgta gagtattaaa ctgccaaaaa caaaaagcga
      781 tagcaatcaa aaaagagttg gaatcctttg gtttattatt acaaaagcag atgggattta
      841 acaaacagtt agggaaaaat aatcctaata gactatatct agcagaatta aaagtctcag
      901 aaaatgatat ctacttactc gaaaaatttg atagagagaa tagggaaaac gttgataaat
      961 cagagggtat gaaaatcata cccaccctcg acgaaaaatc agacgctgaa tcccttgggg
     1021 ctcaagaggg tatgaaaatc ataccgtgcc aaaacgttga taaatcagag ggtatgaaaa
     1081 tcataccaga acttaataat aatatattag acactaatag acacaatata gacactgaaa
     1141 aagaccgcct acaagatcaa ttgttgttag acaattttga gacaattatg acaaacgaca
     1201 gcattgctac gtttgtccct gaacgagtat taaatttgat aaaaacattt tcttcaagtt
     1261 acagtgaagc tcaaaaaacc gtccagacta ttcataatgc aaagaaaaaa gctgaaatag
     1321 aaagtgatat ttcgatagtt tttgaagaac tcgatagtta ttatgtcaat gcagaacaag
     1381 aattatacac gacactgtta aaagcctatc aaaaattaaa aaccgaaaaa gtcgaaaata
     1441 tccagaacct gatttttgtc tatgtaaaaa attggtttat cgaaaaacca atagctgcta
     1501 aagtatcaag tgaaaaacgt ttgaattatg caagctcccc aagcactatt acgaaagact
     1561 ggttagagtg aaactttact gacaaagtga ttgttgcttc atggagtaac attaaaatta
//
LOCUS       DAZKCW010000167         1606 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000167 DAZKCW010000000
VERSION     DAZKCW010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.175"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            44..466
                     /locus_tag="ACG84Z_002848"
     CDS             44..466
                     /locus_tag="ACG84Z_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163622.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            476..679
                     /locus_tag="ACG84Z_002849"
     CDS             476..679
                     /locus_tag="ACG84Z_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163623.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            890..1474
                     /locus_tag="ACG84Z_002850"
     CDS             890..1474
                     /locus_tag="ACG84Z_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9163624.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          566 a          227 c          296 g          517 t
ORIGIN      
        1 ttaagaaaac gttttcttat ttttgatttc gaggtgatag acaatgaaaa ataagtttat
       61 tttatcttta ggtattttaa ctattggaat tagtgtaact ggaactacaa ttcctacatt
      121 tgctgatagt acaaatgaac caactactgt agtagataat aaccaagaat taactccttt
      181 agataggaac ggaatagcca ttggtaaccc aactaacgac ttaactgtta ctgaaaatta
      241 tttaatagtt tctccattac ttgctcgagc agcttctaaa acgatacgag tgacaggaac
      301 gatgattttt gataaagttg gttggccttc tagacctcct caatcacgga attggaaaga
      361 aaaaagaaat ggttattggt actatggaaa attgtattta caaagttata aatcagctgg
      421 aaacaattgg attgcgactt attcaggaac cttaactaga aagtagggat tttttatgcc
      481 agaatttgtg aacacaccaa atttttatca agatagcgat attctaagta aaattaattt
      541 accgaaagaa gaatcagctt tacaagttca gcgaacttta caggagacac aaaaaattca
      601 aaaatcaatt tctaatctag aagattctga agaaaaaaga aaaaaaagag accaaaaaac
      661 atatcaaaaa gaaaaataat gattttaaaa aaagagtgtc tagtcgacat tctttttttc
      721 taattgaaag tgttcataaa atcacccatt tctggacact ttcttttttt gctttatttt
      781 tcaaaaaaac aattcatttc atgttcataa acccataaca atatctatgt tcagttaaac
      841 tatatggata aagttatgtt acaataaaat taatgaagga gtgatttttt tgaaaatagg
      901 atacgcccgg gtatctactg gtttacaaaa tttggattta caagaagaca gcctaaataa
      961 atttggttgt gaaaaaattt ttactgatca tatgagtggg gcaaaaagta atcgaccagg
     1021 attagaaatg gccattgatt ttgttcgctc tggcgataca cttgtcgttt ggcgcttaga
     1081 tcgtttaggt agaaatatgg aagatttgat ttcaatcgtc aatcgactga atgagcgtgg
     1141 tgtgagtttt catagtattc aagaaaatat tacgatggac aaatcaagtt ctacaggaca
     1201 gctcatgttt catttgtttg cggcatttgc agaatttgag cgtaatttga tcctggaacg
     1261 atccgcagca ggacgagcag ctgctcgtgc aagaggacgg tttggtggtc gtcctgaaaa
     1321 attgtctgaa caagatttgg aattactgaa gactttagtg gatagcggta cacctattaa
     1381 gactattgcg gaacggtgga acgtctcaag aaccaccatt tatcgttatt tggcaaaaat
     1441 ggaggagaaa aatggaaaga caaattctca ttagtttttg tcatttaatg ctgaaaattt
     1501 ttgccattta tctagaaaag tgacaatagt atgagaattt tttgtaagtg tctactgata
     1561 acttattctc aaatgttgta aggattttat tcatttgtta atatta
//
LOCUS       DAZKCW010000168         1554 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000168 DAZKCW010000000
VERSION     DAZKCW010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.176"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            41..1507
                     /locus_tag="ACG84Z_002851"
     CDS             41..1507
                     /locus_tag="ACG84Z_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFP9163625.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          430 a          290 c          327 g          507 t
ORIGIN      
        1 ataatatttt ctgaaaattt aaagaattgg ggtatagatt atggaaaaac agcaagacaa
       61 gggcttcttc gggcagccga agggattgtc aactttgttc ttcactgaga tgtgggaacg
      121 atttagttat tacggtatgc gtgcattact tatctattat atgtacgata cagttgccaa
      181 cgggggactt ggattaccac gagcaacagc attagctatc atgtcgatct acggatcttt
      241 gatctacatg tctagtatcg tcggcggatg ggtatctgac cgagtgttag gagcaaaacg
      301 cactgtattc ttcggtggag ttttcattat gcttggccac atcgtcttgg ctttaccatt
      361 tggtgtaagt acattgtttg tttcgatggc attgattatt atcggaaccg cctttttgaa
      421 accaaatgtt tctggcatgg tcggacatct ttattcaaag actgacttgc gaagagatgc
      481 aggattttcg attttttaca tgggtgtcaa cttaggggca ttattagcac cactaatcgt
      541 tggtacaatc ggtcaagaat ataactatca tttagggttc tctttagctg ctattgggat
      601 gttctttgga ttattacaat acatcatcca aggacgcaag acattagacg gagtgggtac
      661 aacaccgccg aatcctttga caactgaaga acgtaaagga ttcatccgta acttgatcat
      721 cgcacttgtt gttatcgctg cagtattcgg cggggcacaa ctaactggtc atctgacaat
      781 tgactttttt gtcaatacaa tcagtgtatt ggggattatc ttaccgttgt attactttat
      841 caaaatgctg acttcaaaag atgtaactgc tgaagaaaaa ccaagagtat gggcttatat
      901 cccattattc cttgcagcaa tcattttctg gtcattacaa gaacaaggtt catctatctt
      961 agctttattt gctagtgaac gtacacaatc tacgctattt ggtgtaacga tccaagcaag
     1021 ctggtatcaa tcattgaatc caattttcat ctttattctg acaccagtat tcgtaacgat
     1081 gtggacgaaa cttggtgaac gtcaaccatc tacagtagtg aaattctctc ttggactttt
     1141 atttgcagga ttatcgtact tgctattgat gttgccgggt atgctttatg gtacaagtgg
     1201 aaaagtaagt ccattgtggt tgttgggaag tttcttcatc gtggttattg ctgaattgtg
     1261 tctttcacca gttggtttgt ctgtgacaac aaaattagca ccacgagcat ttgaatcaca
     1321 aacaatcgct atttggttct tagctgatgc ttcttcacaa gcaatcaatg cacaaattgc
     1381 acgcttctac acaccgggaa cagaatctgc ttacttcggt attatcggtg cagtagcaat
     1441 cgtcggtggt atcttgctat ttactgtgaa agaaccaatc aaaaaactaa tgggctctat
     1501 tcattaatca atgaacataa aaacaggaat tgcttatttg cagcagttcc tgtt
//
LOCUS       DAZKCW010000169         1549 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000169 DAZKCW010000000
VERSION     DAZKCW010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.177"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(173..1030)
                     /locus_tag="ACG84Z_002852"
     CDS             complement(173..1030)
                     /locus_tag="ACG84Z_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFP9163626.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(1316..>1549)
                     /locus_tag="ACG84Z_002853"
     CDS             complement(1316..>1549)
                     /locus_tag="ACG84Z_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFP9163627.1"
                     /translation="KEKPLKEKFLNLIYDEIAIDPYKGEQKTGDLSGIWSSGFKYAGT
                     TYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
BASE COUNT          453 a          314 c          215 g          567 t
ORIGIN      
        1 tctgtctttc aacattggag gaagttttta tttcttgaac ttggtgcact tctaattgct
       61 tattttcaga tggtgtaatt gcttgctgct ttttctttgc ttctgcttct ttttttattt
      121 tggcgagtcc tttgttgttc ccaaaaatat caagtccttt gatgtcagcc aattactcca
      181 cctccgcata ccaattctcg tgttcttcca attctttcaa aatactgata aataattcgt
      241 ggcttttgcg atcccattgt tttaagagac ctttctttgt cttctccatc gtaatacctg
      301 atccgtcgta tcgttttaag cgcgcatttt tgagtacaac atttttaatc aaatgttccc
      361 cataaatctc ttgggcttgt ttatacattt cctgatctac tgcgtcaccg ctttccaaca
      421 tgaaaggaat aacaccagca acatataaat ttgtatcaaa ttctttcaca aaaaagtcca
      481 tatactcaag atattgcatc gcatttctca tcgattttac ttgggtctgt aagacgacga
      541 ttgcccaatc cgcaatgtac atcgcggatt tactatatac agaaatagaa ggtgggacat
      601 ctaaatagat gacgtcaaac tcatcaaata atggttctag cttttctttc atatatttga
      661 attgggataa tgaatcatta tattggtctt tgatccaatc atcatacatt tcaaaggaca
      721 tgtctgctgg aagtatatag aggttattga ttactttata gacagcctct ttaggtggaa
      781 gattgtttat caacacgtca gtcacagtat tttcgtaaac aatcggttca ccttctccgc
      841 ctccttcttc gttagtgaag ttcatatgcg ttaagttcat cacatcagaa gtatttcctt
      901 gcatatccaa gtcaattatc aaggttcttt ttccttcatt aactgctgat tcaaacccta
      961 acatttgcgc gcacgtactt ttacctacgc cacctttaaa attaccgatt acatatttct
     1021 tcgctaccac gttcctacct cttttctttt agcaatattc atttgatact attataacat
     1081 atttattttt agttactacc aaaaaaaaga tatatatgta ctaccttata attaataagt
     1141 aaaaggtagt acataaataa ggaaaagctg aaatatattg atttatagct ttcctcaaag
     1201 taatgacgtt atttaattta tcgagaagca gagaatactc gcgactttag tcatgtagac
     1261 gaatcagatt ttcgataaaa aagaagccgt ccttcttaag aacgacaaca aatcactaga
     1321 ttaatttttt caactgttca taaaagtttt catgcgttcc acataacaat actggaataa
     1381 ccttgttttc tataatctcg taagctactc tatatgttgt gcccgcatat ttgaacccac
     1441 tagaccaaat acctgataaa tccccagttt tttgttcacc cttatatgga tcaatcgcaa
     1501 tttcatcata aattaaattc aaaaattttt ctttcaatgg cttctcttt
//
LOCUS       DAZKCW010000170         1461 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000170 DAZKCW010000000
VERSION     DAZKCW010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.179"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(15..1154)
                     /locus_tag="ACG84Z_002854"
     CDS             complement(15..1154)
                     /locus_tag="ACG84Z_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFP9163628.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT          383 a          316 c          263 g          499 t
ORIGIN      
        1 ttattaaaaa aatcttacgc taagtaggat aaaataattc cttgatattt ttcgatcata
       61 tccaaataat tatcgatttc aacatactca tctacttgat gaggcaaagt aacgacacca
      121 ggcccaaaga cgacaaagtc gaaggaatgg ttagctttcg taaattcggc tgcatccgtt
      181 gttgctgccg ctccaactaa aggtaatggc tggctgaatt gttgctgaat gcaatgaatc
      241 aaaggagaat ctggatcagc tttgacaggt attttgttgt aatcgatcat caattccaaa
      301 tgatagtctg tctcttgatt caattcattg acgattgatt gcagcaatgc aatgatttta
      361 tcatttgggt attctggaat cgatcgaatg ttcccttgga gctgcgcatg gcttgggatg
      421 ctgttgactt gattcccgcc actgatcaat gtaacattat ggattgtttt tcctaggaca
      481 ggattctcga ttgtttcagc gaggtgattc atttcagcat ttgctttcgt aatgaattca
      541 tttaggtgat tgattgcatt ataaccttgg tctggcatag agctatgcgc ttcttttccg
      601 tgcgaggtga ctgtatagtt gattgatccc atgtgcgtat acatcaaact gtaattggtt
      661 ggctctccga tgatcaaggc atctaagtca tctacatagc ctgctttcgt gagctgttcc
      721 ccacctagtt cacccacttc ttctccgaca gtggctaata atttgactgt tccgttaaat
      781 ggttttcctg actctttcag ttcgatcatg gcaatcacca ttgctgccaa gccactcttc
      841 atatctgtag caccacgtcc gtacaaacgg ttcccatgga tttctgctgc aaagggtgca
      901 taggtccaag acgattcatc accagccgcc acgacatcca tatgcccaga taggcctaac
      961 acttttcctg attggccctt ttggtaacga gcaatcaaat tatctctacc atctctgtaa
     1021 gaaacaatct ctcctgttat gtcatgcttt gccaaaagct tattcaaata ggctgctact
     1081 tcaccttcgt ttccattcac tgatttaatt cggataatct cttgtaaaat cgcgattttt
     1141 tcttcttttt tcatctaatc ctctcccttg ccatttcttt ttattgtatt tgagtgtgct
     1201 cgaattttca aataggagca accaaagtaa aaatgaagaa agagagccac tttatgaaaa
     1261 atatgctgct acttccctcc tattttattt atacgagagg acttgcccat agattcctat
     1321 tctactgttc tatccttaaa agctcttata tgatgctagt tattgttagc tttccttttt
     1381 caaggatgat cttttcttgt accattcttt gtaaacatca tatacagaag ctagttgcaa
     1441 aaaaactctc tacctgctga t
//
LOCUS       DAZKCW010000171         1446 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000171 DAZKCW010000000
VERSION     DAZKCW010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.180"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            237..>1446
                     /locus_tag="ACG84Z_002855"
     CDS             237..>1446
                     /locus_tag="ACG84Z_002855"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFP9163629.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDY"
BASE COUNT          476 a          230 c          271 g          469 t
ORIGIN      
        1 atatgaatat tgtaacttgt gaataaggaa ttagcaggag aatactagtt cagcataaag
       61 gaagtgatgg gacttctgag acaactttct gttatgcaga aatacacata taaacagaca
      121 ataaacgctt ttccccgttt cttttaattt cctttacaat ttggttattc actaggtttt
      181 taaactttgc tatggtaaga tgatagaggc attattttat ggttaggagt gtatatatga
      241 ataaaaatgg ggagtggaat gcggcacgca gaatattcat tattcttatg gatgtacttg
      301 tattaaatgt atcgatctat cttagttttt tgctgaaatt ccagggagaa gtaccagtga
      361 gaaacttaga aacctttcag cattcagcaa tttttatttc catcatcttt attgcgttga
      421 atattttgtt aggagcttat gtattctata accgaatgat cagtgatatt gtcttcatta
      481 ctgttattgg acaagtacta atagcattgg ggatcatggt agttactttt gctggccgat
      541 ggtttgcatt tccgcgtggc gtcattttga tctcgtttat cctaggtacg atattactta
      601 gtgtttaccg gatagtcgtt tacaaactgt acttaagagt cagtcgtgat aagaaagtcc
      661 ttatcgtggg tttggagaaa gatgtcgcac cagctatcca aaattttcaa tctaagaaaa
      721 acaataaaca taaggttgaa gcagtggcaa tcgataatta ttacgaaaat acaaaaaaat
      781 tgatcgatga tatggatatc gtctatttgg cttctaaaat cccagaagat gaaaaaatca
      841 acatttatca attagtgact aaaaaagaga agaaattatt tttaaatacg acttttgaga
      901 atctgacaat gataaatccg aatattatga attttgaaga tgaaagcatc attgaagctt
      961 ctgggttcag aatccaacca gaatacgaac tattcaagcg tctctttgat atcatcgttt
     1021 cgcttatttt actgatcctc gcctcacctt ttatgctaat cacagcgatt ttggtaaaaa
     1081 caacttcacc tggaccaatc atctataaac aagtacgtat tacgaaaaat caaaaggaat
     1141 tttcaatcta taaattccgt tccatgagtg cgacagctga agcaaaatca ggaccagtct
     1201 tggctaaaag taacgatgca cgtgtgacac cagtaggtaa atttatccgt gctgtacgtt
     1261 ttgacgaatt acctcaaatc tttaatgtat tgaaaggcga tatgtcgatt gtcggtccaa
     1321 ggccagaaag accatttttc gttgatcagt tcaatgaaga aaatccttat tattacttaa
     1381 gacacaatgt acgtgcggga attaccggat atgcacaagt atacggaaaa tatgtatcag
     1441 attata
//
LOCUS       DAZKCW010000172         1425 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000172 DAZKCW010000000
VERSION     DAZKCW010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.181"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..1425
                     /locus_tag="ACG84Z_002856"
                     /pseudo
     CDS             5..1425
                     /locus_tag="ACG84Z_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          590 a          223 c          319 g          293 t
ORIGIN      
        1 ggtcatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 attagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccagag
      121 aaagaccaac ggtcaaccaa tgaacgataa gagaaatggg cattcttggt ttaggcaaca
      181 agagcgaatc gaaaataaag tgcatagtct gagagaagag atcaagcaac aagaaaaaca
      241 agtagaaaaa cttgaaagac aagaagagat aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgaga atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg actttttcag ccgctacgat ccgaaaatac caacggaaat tggaaacatt
      421 agaacagctg aaagaaagat cggaaaaagg aaaagaaaac cttcttcctg aagtacaagc
      481 aatcattgac agcggacgag tgacgcaatg gaaaaaaatc cgaccattta ttttctgaaa
      541 ggctatcgaa aagtcgcttt agaactgaat gaaaacgggg aatttgagga atctaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgta
      661 ccaactgatt ttttgaagga gaaagaaaac gatcattttt atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt cgaattgatc
      781 gatcaactca aaacgttgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcatactca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaatagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaa
//
LOCUS       DAZKCW010000173         1424 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000173 DAZKCW010000000
VERSION     DAZKCW010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.182"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..596
                     /locus_tag="ACG84Z_002857"
     CDS             <1..596
                     /locus_tag="ACG84Z_002857"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9163630.1"
                     /translation="LTLSGSSLISNLDKKIISFTARYDINIKGFDYLCEVAKNLPVGW
                     AIRIAGDGTEEERKELKRLIEKNGVLDKIICAGALFGDELINHYIESSIFISTSRSEG
                     LPLVLIEAMTYGLPVISFDHGGAKEILQDGNYGILIKNFDVQDMNNEIEKLSNNRLLM
                     EKYQKFSLERAKDFNEKKIIGEWQTLLNELGNEDVRN"
     gene            593..>1424
                     /locus_tag="ACG84Z_002858"
     CDS             593..>1424
                     /locus_tag="ACG84Z_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /protein_id="HFP9163631.1"
                     /translation="MRTSIKNFNLWKEWYLYIFFIGMIIRAINFYSLLPSTFDSIFFK
                     LIGISGVLLLGIDFIIKFNKRKVTYNILLIAYMVILVITSFVHKEYGLGENLKTIMWA
                     ILQYFLIYQFAFENSDNKRFFKRISWGFIYSWFVLVSMSMVLFFGKFGYEKYYNARHR
                     IRIGFLESRLFGTFSDINNAAIASLVVIVLILFYLYNKKVTGLNKIIFLINLPLQFIY
                     IVLSGSRSTYVVSIIIVAISSFIVVLKRNGTKKDLKNYILAIVSSIGSVLILFALFNA
                     T"
BASE COUNT          504 a          132 c          253 g          535 t
ORIGIN      
        1 cattgacatt aagcggctct agtttaataa gtaaccttga taaaaaaatt atttcattta
       61 ctgccagata cgatataaat attaaagggt ttgattattt atgtgaagta gctaaaaact
      121 tacctgttgg atgggctata aggattgctg gagatggtac agaagaagaa cgtaaagagc
      181 tgaaaagatt aattgagaaa aatggtgtgt tagataaaat tatttgcgca ggtgcattat
      241 ttggagatga attaatcaat cattatatag aaagttctat tttcatatct acttctagaa
      301 gtgagggact accattagtg ttgatagaag caatgactta tggattacct gtaataagtt
      361 ttgatcatgg tggtgctaag gaaatattac aagatggaaa ttatggaatt ttaattaaga
      421 attttgacgt acaagatatg aataatgaga tagaaaaatt gtctaataat cgtttactta
      481 tggaaaaata tcaaaaattc tctttagaaa gagctaagga ttttaatgaa aaaaaaataa
      541 ttggtgaatg gcaaacattg ttaaatgaat taggaaatga ggatgttaga aattgaggac
      601 ttcgattaaa aattttaatt tatggaaaga atggtatcta tatatatttt ttatagggat
      661 gattattcgt gcaataaatt tttatagttt attaccgtcc acttttgata gtattttttt
      721 taaacttata ggaatttcag gagttttgct attagggata gatttcataa ttaaatttaa
      781 taaaagaaaa gtaacttata acattttatt gatagcatat atggtgattt tagtaataac
      841 gagttttgtt cataaagaat atggtctagg agaaaactta aagactataa tgtgggcaat
      901 cttacagtat tttttgattt atcagtttgc ttttgagaat agcgataata aacgattttt
      961 taaaaggata agttggggat ttatttatag ttggtttgtt ttagtatcaa tgtcaatggt
     1021 tcttttcttt ggtaaattcg gctatgagaa atattataat gctagacata ggatcagaat
     1081 tggtttttta gaatcaagac tgtttgggac gttttctgat attaacaatg ctgctatagc
     1141 atctttagtt gttattgtcc taatcttatt ttatctttat aataaaaaag tgacaggatt
     1201 aaataaaatc atttttttaa ttaatcttcc attacaattt atttatatag tattaagtgg
     1261 gtcacgatct acctatgtgg taagtataat aatagttgcc atatcatctt ttattgttgt
     1321 gttaaaacga aatggaacaa aaaaagattt aaaaaactat atccttgcta tagtatcttc
     1381 tattggttct gttctgattt tattcgcttt gtttaatgca acta
//
LOCUS       DAZKCW010000174         1424 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000174 DAZKCW010000000
VERSION     DAZKCW010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.183"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(150..1337)
                     /locus_tag="ACG84Z_002859"
     CDS             complement(150..1337)
                     /locus_tag="ACG84Z_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFP9163632.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAZKCW010000175         1376 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000175 DAZKCW010000000
VERSION     DAZKCW010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.184"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..110)
                     /locus_tag="ACG84Z_002860"
     tRNA            complement(26..110)
                     /locus_tag="ACG84Z_002860"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(74..76),aa:Leu,seq:caa)
     gene            complement(128..199)
                     /locus_tag="ACG84Z_002861"
     tRNA            complement(128..199)
                     /locus_tag="ACG84Z_002861"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(165..167),aa:Gln,seq:ttg)
     gene            complement(209..281)
                     /locus_tag="ACG84Z_002862"
     tRNA            complement(209..281)
                     /locus_tag="ACG84Z_002862"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:His,seq:gtg)
     gene            complement(343..427)
                     /locus_tag="ACG84Z_002863"
     tRNA            complement(343..427)
                     /locus_tag="ACG84Z_002863"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(391..393),aa:Leu,seq:caa)
     gene            complement(448..518)
                     /locus_tag="ACG84Z_002864"
     tRNA            complement(448..518)
                     /locus_tag="ACG84Z_002864"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(484..486),aa:Cys,seq:gca)
     gene            complement(564..635)
                     /locus_tag="ACG84Z_002865"
     tRNA            complement(564..635)
                     /locus_tag="ACG84Z_002865"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(601..603),aa:Gln,seq:ttg)
     gene            complement(647..719)
                     /locus_tag="ACG84Z_002866"
     tRNA            complement(647..719)
                     /locus_tag="ACG84Z_002866"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(684..686),aa:His,seq:gtg)
     gene            complement(722..795)
                     /locus_tag="ACG84Z_002867"
     tRNA            complement(722..795)
                     /locus_tag="ACG84Z_002867"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(761..763),aa:Trp,seq:cca)
     gene            complement(802..882)
                     /locus_tag="ACG84Z_002868"
     tRNA            complement(802..882)
                     /locus_tag="ACG84Z_002868"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(846..848),aa:Tyr,seq:gta)
     gene            complement(884..959)
                     /locus_tag="ACG84Z_002869"
     tRNA            complement(884..959)
                     /locus_tag="ACG84Z_002869"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(924..926),aa:Phe,seq:gaa)
     gene            complement(995..1067)
                     /locus_tag="ACG84Z_002870"
     tRNA            complement(995..1067)
                     /locus_tag="ACG84Z_002870"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1032..1034),aa:Asp,seq:gtc)
     gene            complement(1077..1149)
                     /locus_tag="ACG84Z_002871"
     tRNA            complement(1077..1149)
                     /locus_tag="ACG84Z_002871"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1114..1116),aa:Val,seq:tac)
     gene            complement(1165..1236)
                     /locus_tag="ACG84Z_002872"
     tRNA            complement(1165..1236)
                     /locus_tag="ACG84Z_002872"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1201..1203),aa:Glu,seq:ttc)
     gene            complement(1251..1339)
                     /locus_tag="ACG84Z_002873"
     tRNA            complement(1251..1339)
                     /locus_tag="ACG84Z_002873"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1303..1305),aa:Ser,seq:gga)
BASE COUNT          388 a          362 c          318 g          308 t
ORIGIN      
        1 aagaaagttg ctatattgat aattataccg gcggccgggg tcgaaccggc acgtcctcaa
       61 cggacactgg attttgagtc cagcgcgtct gccaattccg ccacgccggc aaatttaaaa
      121 ataataactg gggtagctgg attcgaacca acgcatgagg gagtcaaagt cccttgcctt
      181 accgcttggc tataccccaa gaataaaggg cgaatgatgg gaatcgaacc cacgaatgcc
      241 ggagccacaa tccggtgcgt taaccacttc gccacattcg ccatcataaa agatgttatt
      301 taatttctca ataaaaaact aagatgaaga catcttagtc aataccggcg gccggggtcg
      361 aaccggcacg ccctcaacgg gcactggatt ttgagtccag cgcgtctgcc aattccgcca
      421 cgccggcaag ttgatttatt agtactaagg cggtaaccgg atttgaaccg gtgatgaagg
      481 ttttgcagac ctctgcctta ccacttggct ataccgccat tatactatta tcaatctaca
      541 aaataaagaa taaattatag aaactggggt agctggattc gaaccaacgc atgagggagt
      601 caaagtccct tgccttaccg cttggctata ccccaagaat aaaaagggcg aatgatggga
      661 atcgaaccca cgaatgccgg agccacaatc cggtgcgtta accacttcgc cacattcgcc
      721 atggcagggg cagcaggaat tgaacccaca ctaacggttt tggagaccgc tgttctacct
      781 ttaaactatg cccctataaa atggaggaga gtggattcga accactgaac cctaaggaac
      841 ggatttacag tccgtcgcgt ttagccactt cgctactcct ccatggtggc gcgggacaga
      901 atcgaactgc cgacacacgg agcttcaatc cgttgctcta ccaactgagc taccgcgcca
      961 tattttaaaa ttattaattg aataacaaga acgacggttc cgacgggaat cgaacccgcg
     1021 atctcctgcg tgacaggcag gcatgttaac ccctacacca cggaaccagt tcattatgga
     1081 ggttaacggg atcgaaccgc tgaccctctg cttgtaaggc agatgctctc ccagctgagc
     1141 taaacctcca acattcaatt aaaatgaccc gtacgggatt cgaacccgtg ttaccgccgt
     1201 gaaagggcgg tgtcttaacc gcttgaccaa cgggccaggt aaatttgcta cggagagtaa
     1261 gggattcgaa cccttgagac agtttgcacc atctacatga tttccaatca tgctccttcg
     1321 gcctctcgga caactctcca gagtgaaaga agctcaatac tctttctcaa aatgag
//
LOCUS       DAZKCW010000176         1374 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000176 DAZKCW010000000
VERSION     DAZKCW010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.185"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            33..1372
                     /locus_tag="ACG84Z_002874"
     CDS             join(33..474,474..1372)
                     /locus_tag="ACG84Z_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFP9163633.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          576 a          177 c          239 g          382 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaaat ggactatctc cagtagaata tcggaaacag tccattaaat agtt
//
LOCUS       DAZKCW010000177         1364 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000177 DAZKCW010000000
VERSION     DAZKCW010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.186"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(140..1288)
                     /gene="tnpB"
                     /locus_tag="ACG84Z_002875"
     CDS             complement(140..1288)
                     /gene="tnpB"
                     /locus_tag="ACG84Z_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="HFP9163634.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          392 a          242 c          217 g          513 t
ORIGIN      
        1 taaacctgac ggttcttaac gcttgaagtg ggagcttctt gggaatagag catacttgat
       61 agcgtatttc tttactaaca gcggtgtctc ttatttacca agctatcccc gtagttccta
      121 cggttcttga tgattggatc taagccaatc ccatagaatg tagtcttaga ccttcggtca
      181 gaatattgat actagcattg atatcacgat catgatgagt atgacaaaca ggacaagtcc
      241 attctcgaat ttcaagagat ttcttgccat ctttatgtcc gcactctgaa caaatctgac
      301 tagacggaaa ccatttatct actttgatga tttttcgtcc ataccagtca gccttgtatt
      361 gtaatttagt cacaaacttt gaccaagaaa catcagaaat acttttagct aatttatgat
      421 ttcgcaacat accttttgtg tttaagtctt caatacagat aatatcgtga tttttgatca
      481 tttctgtact caacttattc agaaaatcag tacgttgatt cattactttt tcatgcaatc
      541 tagctacttt gcgtttttgt ttttgataat ttttagcttc aaatagattg gtacctttat
      601 ttttagccaa taaagcacgc ctagacaatt tgcgttgttc acgctttagt ttcttttcca
      661 ttttggacgt gaatttatta ttatcaattt tttgtccatc agaaagaatc gcaaagtcca
      721 taatacctaa gtcaatacca attgtggaat tagttttagg taattcgata atttcttctt
      781 tacacaacaa agaaatatag tatttaccgc tagaatgacg tgatattgta gcggatttga
      841 taatcccttt tggttgtcta tgaagcttaa ttcttactaa tgacttcaat ttaggaactt
      901 tgatgaattt actatcaatc aaagcaactg taccattttg attattcgtt gtataactct
      961 gaacaggatt tttcttactt ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat
     1021 tcttgtatgc tttatctaaa ttaagttggg cattggctaa agcaaggcta tcaatttctt
     1081 tcaaaaacgg aaattctttc ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag
     1141 aatcattttt aacttcttca tacgcctttt ttcggtcatc aagcattaga ttgtagacct
     1201 tacggacaca accaaaagat ttggcaaaga agatttcttg ttcctctgtt ggatagattc
     1261 tgaatttgta tgcttttagt tgttccataa agttcaccta ctttctattt atgattgttt
     1321 ccttgatttt ggatatactt cttaatcaca tcaattggtg cgcc
//
LOCUS       DAZKCW010000178         1360 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000178 DAZKCW010000000
VERSION     DAZKCW010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.187"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>1360
                     /locus_tag="ACG84Z_002876"
     CDS             82..>1360
                     /locus_tag="ACG84Z_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFP9163635.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQ"
BASE COUNT          463 a          262 c          257 g          378 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat
//
LOCUS       DAZKCW010000179         1299 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000179 DAZKCW010000000
VERSION     DAZKCW010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.189"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(62..286)
                     /locus_tag="ACG84Z_002877"
                     /pseudo
     CDS             complement(62..286)
                     /locus_tag="ACG84Z_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="ACG84Z_002878"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ACG84Z_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          461 a          217 c          177 g          444 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagt
//
LOCUS       DAZKCW010000180         1296 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000180 DAZKCW010000000
VERSION     DAZKCW010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.190"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1051
                     /locus_tag="ACG84Z_002879"
     CDS             <1..1051
                     /locus_tag="ACG84Z_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFP9163636.1"
                     /translation="KEIEEKIIQYDGLAKLKDAKVVSGEQRINREDLSDEFKNVVSLE
                     ATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAKQNNLKLGDEVDLELLDIE
                     KSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDYSTSQEILNNSENNEIANK
                     ILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEESLESVSGIKYIIKVMTYSI
                     MLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQFIFELIFISIPSIISSLFL
                     GNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQSYLILISIIVLSVVFASS
                     LMLIKKPKEILSKIS"
     gene            1061..>1296
                     /locus_tag="ACG84Z_002880"
     CDS             1061..>1296
                     /locus_tag="ACG84Z_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFP9163637.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHR"
BASE COUNT          541 a          116 c          217 g          422 t
ORIGIN      
        1 aaaagaaatt gaagaaaaaa taattcaata tgatggatta gcaaaactaa aagatgctaa
       61 agtagttagc ggagaacaaa gaataaatag agaagattta tctgacgaat ttaagaatgt
      121 tgtttcactc gaagctacaa ataatactaa aagaaatatt ttatttagta gtggagtatt
      181 tacaattaaa gaaggtaaaa atatagaaga aaatgataag aattcaatta ttgttcatga
      241 agaatttgct aaacaaaaca atctaaaatt aggtgatgaa gttgatcttg aattactaga
      301 tattgaaaaa agtggaaaaa taaaaagtca taaatttaaa attataggga tcttttctgg
      361 taaaaaacag gaaacatata caggattatc ttctgatttt agtgaaaata tggtgtttgt
      421 agattattca acaagccaag agatattaaa taattcagaa aataatgaaa ttgcaaataa
      481 aattttaatg tattctggta gtgcagaatc tacagactta gccttaaaca aattgaaaga
      541 gcttaaaatt gatgagtcaa agtattttgt tgaaaaagat tctaatgcgt ttgaagagtc
      601 tttagagtca gtgagtggaa taaaatatat aataaaagta atgacttatt ctattatgtt
      661 aggtgggatg gttgttcttt cattaatctt gattctatgg ttaagggaaa gaatttatga
      721 aataggtata ttcttatcta ttggaacatc taagatacaa attataatgc aatttatatt
      781 cgagttaata ttcatatcga taccaagtat aatatcttcc ttatttttag gaaatgtatt
      841 actaaaagta attgtagatg gattcattaa ctcagaggat tcaatgattt ccggtggaag
      901 tttaataaat aatagtagtt ttatgtcaaa tataacaaca cttggacaaa gttatttaat
      961 attaataagt attattgttt tatcagttgt atttgcttct tcattaatgt taatcaagaa
     1021 gcctaaagaa atcttatcaa aaataagtta ggagaaaata atggatatat tagaaataaa
     1081 gaatgtagca tatagttatg caaattctaa agaaaaagtt ttgtcaggag taaatcaaaa
     1141 atttgaactt gggaagtttt atgcgatagt aggaaagtca ggaacaggaa aatctacact
     1201 tctttcctta cttgctggac ttgataaacc tcaaacagga aaaatattgt ttaagaatga
     1261 agatatacaa aataaaggat atagtaatca tagaaa
//
LOCUS       DAZKCW010000181         1145 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000181 DAZKCW010000000
VERSION     DAZKCW010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.193"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            64..330
                     /locus_tag="ACG84Z_002881"
     CDS             64..330
                     /locus_tag="ACG84Z_002881"
                     /inference="COORDINATES: protein motif:HMM:NF021126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFP9163638.1"
                     /translation="MTSTYASFDKDNLYYDFPSVSGFSSMNNKKYLLMLTRLGYSTSN
                     VRAKRNGGTVITDILLSNQYQVIPNQEIQHQATSGVKIIESEVS"
     gene            433..708
                     /locus_tag="ACG84Z_002882"
     CDS             433..708
                     /locus_tag="ACG84Z_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163639.1"
                     /translation="MTNLESRQFDPCWHQIDAQTKELLLGWEENQVVRDFSLNFIMID
                     YYNLATSMQRFPNYGMDIDSFKQKSFSGEIQNEESNNLVIPILYEPG"
     gene            718..924
                     /locus_tag="ACG84Z_002883"
     CDS             718..924
                     /locus_tag="ACG84Z_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163640.1"
                     /translation="MDGEEYPYKVAFDDLIQLSNLPKDSNMKIAGEFFAPGFLVGLVI
                     SSIATGCFLFLLFLDYIKKTEDIP"
BASE COUNT          393 a          184 c          204 g          364 t
ORIGIN      
        1 acaatcaacc aaactctaac agaatttgaa gtatatcaag aatattggga accactaaaa
       61 aaagtgactt caacttatgc atcctttgat aaagacaatc tctactatga tttcccctca
      121 gtatcaggat ttagttcaat gaacaataaa aaatatttac taatgttaac gagattaggg
      181 tactcaacaa gtaacgtccg tgctaaacgg aatggtggta cagttattac ggatattttg
      241 ctaagcaacc aataccaagt aattcctaat caagaaatcc agcatcaagc gactagcggt
      301 gtaaagatta tagaaagcga agtgagttaa acctcagata ttgcttcttt ttcatttgac
      361 gttctagaag taacaaaaga tgagttactt tatgtttatt ttcccgtcaa cttggccaat
      421 aatttgcact atgtgaccaa tttggaaagt cgacaatttg atccctgctg gcatcaaatt
      481 gatgctcaaa cgaaagaatt gttgctaggt tgggaagaaa atcaagtagt tcgtgatttc
      541 tcattaaatt ttattatgat tgattactat aatttggcga catcaatgca acggttcccg
      601 aattatggta tggacataga ttcattcaaa cagaaaagct tttctggaga aattcaaaat
      661 gaggaaagca ataatcttgt tatacctatt ctctatgaac caggttaggt ttttactgtg
      721 gacggggaag agtatcctta caaagtagct tttgacgatt tgattcaatt gtctaactta
      781 ccaaaagata gtaatatgaa aattgctgga gaatttttcg caccaggatt cttggtaggc
      841 ttggtaatct ctagtattgc aactgggtgc tttttatttt tactttttct ggattatatc
      901 aagaaaacag aggatattcc ttaggaaaat cacaatctaa atcttcccta gaaactatag
      961 aatgacaagg gggatataag caaattccta aatgattaaa tagggtgcgt tactagttag
     1021 ctccatagta agattttttc aaaattttct tgaggttgga tcaaaaaggg ctcttttcaa
     1081 ttagattaaa gacactcata caaaatagag aaacgaactt ataatcgcgt tcgtttccct
     1141 attta
//
LOCUS       DAZKCW010000182         1118 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000182 DAZKCW010000000
VERSION     DAZKCW010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.194"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1112
                     /locus_tag="ACG84Z_002884"
     CDS             <1..1112
                     /locus_tag="ACG84Z_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFP9163641.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT          341 a          210 c          231 g          336 t
ORIGIN      
        1 ttcctattct ttatttaatg gaacaacctg ctttgtctgt ttctcaatca tttttagaca
       61 aaaatgaaat ttcttatatg acccatactt ctggtacaac tggtatccct aaacttattt
      121 gtcattctgc tcattctatg ggatggcgga cgaaatggca aaaaacagtt ttcacaaaaa
      181 tttcggaaaa gaaattaatc gcttttcaca tctctccagt gcattccaga ttcaatattg
      241 gtatctcttc tttgatgtcc atgggatttc ctatgatgcc tttagcaaac gcacaaagtt
      301 caaaagttgt tcatatgttg gaagctcacc ggccaattgc actagagacc catccgaata
      361 actttgttca gtggcgtttt actgctaagg agcatccaga agctttttcg ggtatccgat
      421 actatcactc cacttttgat gctataaaca accagacaat gaagacattt ttgcgaacgt
      481 cgatggcaca ggatgcggta tttcttcaag tatatggcca aagtgaatgc ggaccaatga
      541 ttcttaaggc tcatacacta gagagtttga aaacaagtga tgcaagagat atgggcgttg
      601 gactggaaga catgacaagc gctcggatta cagattcagt tgggaatgtc ctacctgaaa
      661 acacagatgg tcatatacaa ttactgtcta aaggacgggc tttgacttat tacaaggaag
      721 atgcacggtt ccaggaaaat gtttatggcg attggtggga tagcggagat tacggtttta
      781 tggataagca tggccaccta tttttgaaag atcggcaagt ggatttgatc gaaacgatca
      841 atagtacatt agctattgaa gactttttat tagattcgtt agattttttg gcagaagtag
      901 tgattgtaag ggataaaaat cattctccac aaccgattat tgctttagct cctgataaag
      961 aaatggattg gaatcgatgg tgggagcaag tccatgaact tcctcgcttg aacgtcccta
     1021 tcatccgtga ttttgatgca atcccgcgga cagctacaat gaaagtgcaa cggcttcaaa
     1081 tcgagaaaga attaaaatca caaaagtcct aactattt
//
LOCUS       DAZKCW010000183         1096 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000183 DAZKCW010000000
VERSION     DAZKCW010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.195"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(70..>1096)
                     /locus_tag="ACG84Z_002885"
     CDS             complement(70..>1096)
                     /locus_tag="ACG84Z_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFP9163642.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
BASE COUNT          355 a          182 c          164 g          395 t
ORIGIN      
        1 gttttgtctc gcttaatttg acaaataata tttttagaaa aagcagtcgg actttctaaa
       61 agaagttcac tattcgatcc tgtcgatgat ttcttcagga aaatcgtcta tttgcttgtc
      121 aattttgctg tctttgtatt tctcttcttg gatagtcaac aaaatctttg taagattccc
      181 ccagtctact gctcttggcg gatcgagcca aaccactact tgagatgcac tttcttcata
      241 tagattattc ctattcgtga ttataacatc cgggaactca ggctttcctg cctctatcac
      301 ttccgtgttc agattaatgt acaagcttaa atttttcttg ataaattgat tataggcagc
      361 accataagaa aaatcgatga tgatctttac tggttcagaa atcagttgaa tgggtatgtg
      421 attgatcaat aataataaat aactgaaaaa aagaaaaaat ttatcttgaa gcaactcttt
      481 gcgttttgac gttagatcat ttatatactc tatcaaatag caataaaatg ctggatagtt
      541 ttctctaaaa aaagaaacat caagtggaaa ttcatcagct ttattaatag tgtaatgcaa
      601 aagtttaaaa tgtattttgg ttaactctct tcggatcaat tggctcgtct cttctcgcaa
      661 cagattaaac tgattttcaa aactttcaat gaatcgttca ttcaaccatt cgattgtttc
      721 atcttcattt tttctcaagt atttttgatc caatttatca tgaagataaa gccaagagag
      781 tgtcttattg ataaaaataa cggatttttc tcctaatact ccttttaagt ggtaaaatcc
      841 tatatccgaa aaaaatagcg actgattgct agcaatatct aaagaatcag cttgttcagc
      901 caacaggttg attgctaaaa agtggaataa tttctttttt tcataagcag acagaggata
      961 atactgtttt aaatctttta acattttttc tgtttttata attataggta gcgtatacaa
     1021 ttccacaaaa cttatctctg ttgagttaaa aagattatat aaaaaaagcc gaatgttttt
     1081 aggattccct gtcaac
//
LOCUS       DAZKCW010000184         1093 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000184 DAZKCW010000000
VERSION     DAZKCW010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.196"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..221)
                     /locus_tag="ACG84Z_002886"
     CDS             complement(<1..221)
                     /locus_tag="ACG84Z_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFP9163643.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEK"
     gene            509..>1093
                     /locus_tag="ACG84Z_002887"
     CDS             509..>1093
                     /locus_tag="ACG84Z_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFP9163644.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKEL"
BASE COUNT          404 a          133 c          201 g          355 t
ORIGIN      
        1 aacttttctt tgactttcaa tatctgagta cgtgtcgtat aggaaccgtt gcggataata
       61 cgaatcgatc cacagtgttc acaatgggaa ggtgagtcat ccaatctccc tttaataaac
      121 tgcgcttgaa cgcctttata ttctttttca atcagccatt cttcatcaaa aaataaatgt
      181 ttatctgtta atccgagtaa ttttctagta tgattatcca tagagcgact cctttggtag
      241 ggtgatgttt tggtcgacta aattttacca aaagtgagtc tctttttgag ttgaaacgaa
      301 gaaaaagtgt tagtagaaaa tcgccttcga ttttccaaca acacaaaata ttatagaacc
      361 ctttattcta aaggatttca aggtgtctgt ttgcatttat tagaaaaaag aaaaagtatt
      421 ggcaacagaa ggtgtcacca acactagata ttatagagcc ataatatgct gtataatatc
      481 tagtgtatag gcttaagtgg aggtatatat gaaaatatta actgttgaag atgataatat
      541 gataagagag ggaataagtg aatatctttc agaatttgga tatactgtta ttcaagctaa
      601 agatggaaga gaagccttgt caaaatttaa tagcgatata aatttggtta tcttagacat
      661 tcagatacct tttataaatg gtttagaagt gttgaaagaa attagaaaga aaagcaattt
      721 accaattcta atcttgactg catttagtga tgaagaatat aaaattgatg catttactaa
      781 tttagtagac ggatatgtag aaaagccatt ttcattgccg gtcttaaaag ctagaataga
      841 ttctttaatt aagaagaatt atggacattt agagaagttt gaatataagg atctatcggt
      901 taattttaat agctatacag ctaaaataaa tggtgaagaa atagatgtaa atgcaaaaga
      961 actagaagta ttaaaatgtt tattggataa taatggacaa gtgttaacaa gaatgcaaat
     1021 tattgattat gtatggaaag atagcgaaga aactccttat gatcgagtaa tagatgtata
     1081 tataaaagaa ctt
//
LOCUS       DAZKCW010000185         1016 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000185 DAZKCW010000000
VERSION     DAZKCW010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.197"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            96..836
                     /locus_tag="ACG84Z_002888"
     CDS             96..836
                     /locus_tag="ACG84Z_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163645.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT          374 a          182 c          197 g          263 t
ORIGIN      
        1 cgctattttc ttaaaataat cagcgcattg ctactgaaaa caatgaatct gtgctattat
       61 tgagaaaagt tccatttttg agaaggatgg tttgaatgaa agaaatcaga cgaaaacatt
      121 tccgttttcc tgcgtacgat gatgagttag gcgtaaaatt aaccaacgac aagaagcgag
      181 tattatttga cggacaagaa gatcttttga ctgaacagaa tcagtccccg tttgaacaga
      241 tgaaagaatt tcatttcacg aacacgaaca ccgagaaaat ccgtcgcaag cgtcgtgcaa
      301 caaatggatt gaagtcagct ccgcgtaagg aaaatttgga aaagcataaa ggaaaattac
      361 cggattatac cggccattac caatcagaaa tcacatcgac aggacgaaaa aaactttttg
      421 gtgattcctc tcgttctgtc agacaaagtg aaacaaggac agagtccaag catactacac
      481 gaaacgcatc tgttgacacg aaggtgcggg agcgttctta ttttgttcct aaatatgtac
      541 ccgcatcgat tatcccagac cctagagaaa gcaaaatttc tgaggatcat ttaatcgaat
      601 cgatgaaaaa aacggatgac tcttatctgt tgttcgatac agaaccgacg ccgtatcaag
      661 aaaaaagaaa tggtgagccg tctgtacgaa cattcaatcg aacaaaaacg ttagaggaaa
      721 caaagcagtc agaagaaaaa aaatcgaaaa aaagccatgg tatcttagaa cgctcattac
      781 aaggattgat cgatgatcaa ggaaactctt tgggagaaaa tagctatttt aaataagtga
      841 tatacaaatt tatattcggc tacagttgga aaggaaacgc tgcggcgttt ccttatttta
      901 tactctatcc gaaagtttat atcgtatcct caaatttttt tgagtttaag cgaatttttt
      961 ctcccaataa gtaagaaaat aatggcaaaa taaaaaaaca aactattttc gcagat
//
LOCUS       DAZKCW010000186          981 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000186 DAZKCW010000000
VERSION     DAZKCW010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.198"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(511..864)
                     /locus_tag="ACG84Z_002889"
     CDS             complement(511..864)
                     /locus_tag="ACG84Z_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163646.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
BASE COUNT          326 a          147 c           99 g          409 t
ORIGIN      
        1 aaaaataaaa acatcttttc attttgagtt attaatggag atgtaaatga ttaacaatat
       61 gtaatttaat tttttattcc tgcattaaga taatttgatt ggtaaataaa aacaaacgta
      121 aattcgttat tttaattcct atttattgtg aacatatcca atttttatca catagatatt
      181 tgtataaaca ttttatgaat gcgcttgtat ttaatttaga aagtgttact atctatttag
      241 gcaaattttt gctaatattt tgttttttca tttaccatct gtagaaatca tttaatgatt
      301 tctatcttct ccttccaact tttctgatga tgcatcatga attaacagtg cattatccat
      361 cttttccatg ttaaaagaac taagaatcaa gataacgtct tgattcttag ttcttttatt
      421 ccttctagaa aataattgtt agcaatatag tttatatttg taaatactaa atcagtagct
      481 tctagttgct ttcctgctta atagttcata ttactcaatg taaaaaataa ttgattgtgg
      541 acattgctca tccactttgt atccacaact ttctttataa taggtatgat aatcactctc
      601 taccatatta attaactctt ttcccccgca aaattcttca atgtctaaat taataaattc
      661 ctctaaaagg gaaagcttag agtcaatcga aagcatttta ggtaacatag tccaaaagtc
      721 attatcatcg tttttacgta gtgtataata tgtttgcttt tctagattta atacataatt
      781 atatgcatca taatctccct ttttttcaaa aaaatttttc atatttaaaa atctactcac
      841 aaattttttc ttgaaactat tcattttctc acctctattt attctttttc ttgtccatag
      901 cataactttt gaatagagta actaaattca aaagctatta tagtataaaa atacactttt
      961 tgttgttcaa atttttcatc t
//
LOCUS       DAZKCW010000187          932 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000187 DAZKCW010000000
VERSION     DAZKCW010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.199"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            199..900
                     /locus_tag="ACG84Z_002890"
     CDS             199..900
                     /locus_tag="ACG84Z_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFP9163647.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT          334 a          161 c          149 g          288 t
ORIGIN      
        1 tgtattattg ttgtttttta tacacaaatc attcgcttca aaacaaatta ttcaatacca
       61 ttgtatattt tttacataat aacaaattat atttgtaaag tattaaaact tgtttctaat
      121 gttggtatgt taaaacttta caaattcttt aaaaaaagtg acaataaata tagtgaacaa
      181 taaggagagg actttttaat gcgtgttaat aaaatcgatt ttcacttttc aaaactcaga
      241 tatcaacctg attttgaaca tttctcggat gaagagttcc aacagatcaa ggaacatact
      301 gttcttcgtt cttataaaaa aggacagatc cttttcgacg atggtgatcc cagacaacgg
      361 ttgtatatct tgaccaaagg actcgttcgt ttagaacgtt atgatgaaag tgcaacttat
      421 tactactatg actatgtgaa tacaaataac ctttttccta tgtcaggaat gtttggagaa
      481 gagacctaca cttatacagc tcaagcgatg actgatattg aaacattcta ccttcctgtt
      541 tcctactatg aaaaattagc acgaaaaaat cccgaacagt tgatctatat gatacaaaaa
      601 atttctaaag tagttgaaat acatgaattg cgtatccaaa tcggattgac ctctagcgcc
      661 tttgaccggg taaaacaaaa tttattcatt ttgaaagaag aattgggcgt accaacaaaa
      721 gatggtcata tcaccattcc ttatccgatc accttaaaag aattagcagt gaatagcggc
      781 acgacacgtg aaactgctgg acaagtaatc aaacaactac gtgattccgg actgttagat
      841 tatgacaaaa agcgttttac tttctgtaag acagctacta ctccagctat gagagaataa
      901 cgcgaacaaa aataagcagt gaccctgata tt
//
LOCUS       DAZKCW010000188          918 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000188 DAZKCW010000000
VERSION     DAZKCW010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.200"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(128..676)
                     /gene="aac(6')"
                     /locus_tag="ACG84Z_002891"
     CDS             complement(128..676)
                     /gene="aac(6')"
                     /locus_tag="ACG84Z_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFP9163648.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          266 a          190 c          139 g          323 t
ORIGIN      
        1 ggtacacggt gttccaaaag tagcttcttc ggaaataagt tggaatttca caaaaattca
       61 agaagtaatt ttcgtaaatt ccttcttatt tcttgaagct gattacttct gtcacaacct
      121 ctttttatta ttgagaattt ggtcgaggaa taatcgtttt tgccatccaa atatccggtt
      181 tgtcccagcc atttgcattt ggtaagacac ctacgatttt ataacctaat ttttcataga
      241 attcatacgg atgttcacga aggttctgga tggaagccac tttatcaaat gtatgctcat
      301 acaggtccgt ttgacttaac gttgttccat ggtctaaatc atccgtacct aaataaatcg
      361 tgattcctcc tctggaagct acttcttttt ctaagtaatt gactaatcga gtacctattt
      421 ggttctttcg tcgggagctt tctacaacta atggatgcaa ttcccaacct gtgataccgt
      481 attgagggat tgcaccaata aatcctacta actcatcttg gtctaccgct gctaccgcga
      541 ttcgttctgg attcatcatt tcttctactt cttctgccga gctgtctcca tattcttccg
      601 gccaagtcag tctcagtaaa tcagaaagct gatctttcaa tactggatta ttacggtcaa
      661 attcactgat tatcatacgt cttccccctt gttcttgctt attctaacag tccttttgaa
      721 aaaacgaaat gttctcgctc aaaaatcttt agctaccaat cagtatctct attctttcat
      781 tatttatctt acttataaaa taaaaaaatt atacagaaac actttattca aaataggaaa
      841 gatcaggaaa gccatcaatt ggaggaaaaa actctgtttg ttcatcatga tatagattat
      901 cttttgcttt aaaaaaaa
//
LOCUS       DAZKCW010000189          905 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000189 DAZKCW010000000
VERSION     DAZKCW010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.201"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..>905
                     /gene="bsh"
                     /locus_tag="ACG84Z_002892"
     CDS             4..>905
                     /gene="bsh"
                     /locus_tag="ACG84Z_002892"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFP9163649.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMN"
BASE COUNT          310 a          123 c          163 g          309 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagtcact attactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tggactaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaagctaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgacgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataa
//
LOCUS       DAZKCW010000190          901 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000190 DAZKCW010000000
VERSION     DAZKCW010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.202"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            81..842
                     /locus_tag="ACG84Z_002893"
     CDS             81..842
                     /locus_tag="ACG84Z_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFP9163650.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
BASE COUNT          239 a          152 c          184 g          326 t
ORIGIN      
        1 taatcaacaa agaaaatgtg atttttttca ctatatttta tcacatgaaa attcattaag
       61 aaagtaggaa tcgaagtatt atgcacacac cagaagaaat tatggaactc agtattcatc
      121 ttggaacaaa aaaaatacat aaacctatct tagctaaact gattttaggt tttatcggag
      181 gagccatgat ttctctaggt tatttggcat acgtacgagt ctctgcttct atcccagaat
      241 ctatggctag cttgactagt ttagttggtg cctcggtttt tcctatcggc ctgctggtca
      301 tccttcttgg cggtggtgaa ttgatcaccg gaaatatgat ggctgtggcg attgccttta
      361 tggataaaaa agtcacattc tcacagctgg ttaagaattg gtcagtgatt acttttgcaa
      421 atattattgg tgcaattttc gttgcctatt tctttggaca ctttgttggt ttaactcatt
      481 caggtgtcta tctcgaccaa gtgattcata ttgctgatca taaaatcgct gtttcttggt
      541 ggcaagcatt aggctccgga ataggttgta attggtttgt cggtttagcg ttatggttat
      601 catatggagc aaaagatgcg gccggcaaag tactaacgat ttggtttcca gtcatgattt
      661 ttgtggcaat cggtttccag catagtgtgg ccaactgttt tgtgatacct gctgccatat
      721 ttgaaggtca agcgacttgg ttagaatttc tctcgaattt tatccccgtt tatattggaa
      781 atatcatcgg cggagctatt tttgtttcag gtttttatta cgttagttat aagcatcatt
      841 aagattgaag gtaatgttca ttcgagcatt accttcaatc tctttatata ctatttatat
      901 t
//
LOCUS       DAZKCW010000191          895 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000191 DAZKCW010000000
VERSION     DAZKCW010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.204"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            361..759
                     /gene="spxA"
                     /locus_tag="ACG84Z_002894"
     CDS             361..759
                     /gene="spxA"
                     /locus_tag="ACG84Z_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFP9163651.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          330 a          121 c          161 g          283 t
ORIGIN      
        1 gaacagtatt atttaaaatg acagaaaaca ttactattaa agaaataaaa aacataaaaa
       61 atcttaagaa atcggtttca tttagctttt gagataaaat aatagtacag ttttatacgc
      121 tgtttcatat gtttagaaaa tttgaattag atttgaaaac tctaattttt aaatgataaa
      181 aaaagcgaga atgctggttt tactgtatat taaccttaga taactttcat ttttttaaaa
      241 aaattatgaa aaaaaggtag ctatttaaaa gttgattatg tataatagaa acagatggga
      301 gattattatg atcttctgtt acaaaaaagt gattcttatc acgaaaagga gtggtgcacg
      361 ttgttaacat tatatacttc cccaagttgt acttcctgca gaaaggctcg tgcgtggttg
      421 caagaacatc agattccatt tgttgaacgt aatatttttt cagaaccatt gaacagttct
      481 gaattaaaag cgattttaca aatgacagaa gacggaacag aagaaatcat ctcgacacgt
      541 tccaaagtat tccaaaaact gaacatggat ttagatgatc tgccgttaca agaattattg
      601 gaacttgtgc aaaacaatcc tggattgctt cgccgtccaa tcatgattga tgataaacgt
      661 ctgcaagttg gttttaatga agatgaaatt cgtcggttcc taccgcgcga tgtacgacaa
      721 ttagaattac gtcaagcaca attgatggct ggattataga aggataatac gaaacttgga
      781 aaagactggc tctttgtcaa atgatgttgg taaagagaaa tcttagaata atttggacag
      841 aacagaaaga agaaaacctc tttctgttct gtttatttgg ttaaaaatgt tttgc
//
LOCUS       DAZKCW010000192          882 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000192 DAZKCW010000000
VERSION     DAZKCW010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.205"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(202..600)
                     /locus_tag="ACG84Z_002895"
     CDS             complement(202..600)
                     /locus_tag="ACG84Z_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFP9163652.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(597..833)
                     /locus_tag="ACG84Z_002896"
     CDS             complement(597..833)
                     /locus_tag="ACG84Z_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFP9163653.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
BASE COUNT          278 a          158 c          122 g          324 t
ORIGIN      
        1 ataaaaaatc agcccactag ttctaaacca ctatttccta ctattcactc ttttgtattc
       61 cttttaaatc aattatttca aaattaatcc atattttcca tatttttatg aaaaaactat
      121 tttgtatgat taaacataaa aaaatcagca tattccttaa tgacatgctg atctaattga
      181 gaaataaagt ttttaattcg ttcattttat tgcggtttgt cgtaaataac tggttatctt
      241 ggactttagt gaatcgaaat ccaatgaact agtggtaatc attatgataa aatcaacagc
      301 ttcttgacga gaaaaagcaa ctggacaatt attcaattga agaaacaaca acatggcaac
      361 aagagcagtt cgtttattgc cattatgaaa aggatgtttt ttagctaaat taattgctaa
      421 aatcgccgct ttttcataga tttcaggata gagttcttga ttgaatactg cttgtgaagg
      481 ctgtttgacg gccatatcta atgcatttgc atcttttaca ccgatcattt cgcctggcga
      541 gtgacgtaaa ataactttcg cgttgatttt gataatttct ttagtcgaaa gatacctcat
      601 aaatcaacca aatcttttaa cgcgtcttca tattgattca tgatcgaatc aactaatgaa
      661 tcaatatcag gttcttcttg tgctttgatc attcgtacag aaccatcaga ttgaaaaaca
      721 taactgattg cgtcacctgt ctgcacaccc atgaattctt ttacttctgg tgggatagtt
      781 gttacatcgc tattgccaga ttttctaatt ttatactttt tcattttttt catatttcgc
      841 caccctctat accattctca ttctatagta agtacattat at
//
LOCUS       DAZKCW010000193          802 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000193 DAZKCW010000000
VERSION     DAZKCW010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.207"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>802
                     /locus_tag="ACG84Z_002897"
     CDS             <1..>802
                     /locus_tag="ACG84Z_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFP9163654.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSW"
BASE COUNT          272 a          152 c          150 g          228 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aa
//
LOCUS       DAZKCW010000194          772 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000194 DAZKCW010000000
VERSION     DAZKCW010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.208"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..694
                     /locus_tag="ACG84Z_002898"
     CDS             <1..694
                     /locus_tag="ACG84Z_002898"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase family
                     protein"
                     /protein_id="HFP9163655.1"
                     /translation="NLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEE
                     EQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYI
                     ESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYL
                     LEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIEN
                     GRKEIYKRAYKD"
BASE COUNT          336 a           50 c          128 g          258 t
ORIGIN      
        1 aaatttagaa actaatgtaa aaattcctaa tattgaatat tcgtatatta gtgatgaatt
       61 atctatacta ggttataaag aaattaaagg aactttttta acaccagaaa tttattctac
      121 tatgtcagaa gaagaacaaa atttgttaaa acgagatatt gccagttttt taagacaaat
      181 gcacggttta gattatacag atattagtga atgtactatt gataataaac aaaatgtatt
      241 agaagagtat atattgttgc gtgaaactat ttataatgat ttaactgata tagaaaaaga
      301 ttatatagaa agttttatgg aaagactaaa tgcaacaaca gtttttgagg gtaaaaagtg
      361 tttatgccat aatgatttta gttgtaatca tctattgtta gatggcaata atagattaac
      421 tggaataatt gattttggag attctggaat tatagatgaa tattgtgatt ttatatactt
      481 acttgaagat agtgaagaag aaataggaac aaattttgga gaagatatat taagaatgta
      541 tggaaatata gatattgaga aagcaaaaga atatcaagat atagttgaag aatattatcc
      601 tattgaaact attgtttatg gaattaaaaa tattaaacag gaatttatcg aaaatggtag
      661 aaaagaaatt tataaaaggg cttataaaga ttgattatat aatatatgaa aagctattat
      721 aaaagacatt agtattaaat agtttaaaaa aatgaaaaat aataaaggaa gt
//
LOCUS       DAZKCW010000195          768 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000195 DAZKCW010000000
VERSION     DAZKCW010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.209"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(109..>768)
                     /locus_tag="ACG84Z_002899"
     CDS             complement(109..>768)
                     /locus_tag="ACG84Z_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HFP9163656.1"
                     /translation="RIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQ
                     PLEAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLT
                     DVKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQY
                     QFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEA
                     A"
BASE COUNT          213 a          176 c          147 g          232 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggtttggtt
      421 atcaaattcc tttccccggt ctgtatgaaa aagcttgacg tctgttaaag aatacggtat
      481 ccgtccaaag gcttctttta ccaatgaggc atctttcttc tcaccacagg aataaccaat
      541 aatttctcga ttaaacaaat caagtattaa gcagatataa tgccactttt tccccacgcg
      601 aacataagta agatccgtaa cgatggcttc caatggctgt tcttgtgtaa aggtccgatc
      661 taatacattc gctgttttcg cttcattaca agctgttcgt tgccctttaa aatgagcgat
      721 cgtataggta gatgtcaatc cgcggcgttt catgattcga ccgattcg
//
LOCUS       DAZKCW010000196          717 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000196 DAZKCW010000000
VERSION     DAZKCW010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.210"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            26..706
                     /locus_tag="ACG84Z_002900"
     CDS             26..706
                     /locus_tag="ACG84Z_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFP9163657.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPA"
BASE COUNT          253 a          123 c          145 g          196 t
ORIGIN      
        1 gaaaaagata gcaggaggaa tgacgatgaa tcattttaaa ggaaagcaat ttcagcagga
       61 tgtgattatt gtagccgtgg gctactatct tcgttataac cttagctatc gtgaagttca
      121 agaaatctta tatgatcgtg gcattaacgt ttctcatacg acgatttatc gttgggtgca
      181 agaatatggc aaactactct atcaaatttg gaaaaagaaa aataaaaaat ccttttattc
      241 atggaaaatg gatgaaacgt acatcaaaat taaaggaaaa tggcattatt tgtatcgagc
      301 catcgatgca gatggtttaa ccttggatat ttggttacgt aaaaaacggg acacacaagc
      361 agcctatgct tttcttaagc ggttagtgaa gcagtttgat gaaccgaagg ttgtagtcac
      421 agataaagcc ccctctatta caagtgcctt taagaaacta aaagaatacg gcttttatca
      481 agggacagaa catcgtacca ttaaatacct gaataatttg attgaacaag accatcgtcc
      541 agtaaagaga cgcaataaat tctatcgaag tttacgcact gcctctacca cgattaaagg
      601 catggaagcc attcgaggat tatataagaa aacccgaaaa gaaggcactc tcttcgggtt
      661 ttcggtctgt actgaaatca aggtattatt gggaatccca gcttaaatca tagatac
//
LOCUS       DAZKCW010000197          707 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000197 DAZKCW010000000
VERSION     DAZKCW010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.211"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(64..639)
                     /locus_tag="ACG84Z_002901"
     CDS             complement(64..639)
                     /locus_tag="ACG84Z_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFP9163658.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          237 a          152 c          125 g          193 t
ORIGIN      
        1 caaataataa aatgaaaaaa cagagccaga ttagcattat tttgctaatc cagctctgtt
       61 tattcagcct atttttcttt ttgaatatat caagcgttgg ggcaacatag tgatgactaa
      121 tgaaacaacg acgatagaca acaagcgatc aaggtagtct gtacccgcct gtaccaagat
      181 cacacttgtt gtctgactta aacctaaccc atgtaatagc tgaacgatca tactggatcc
      241 tgaggaggtg atcccgccaa ataactgaac ggtaatgatc gaagaaacga tcgttccagg
      301 taccgacaaa atcaaagcga gtaataacag tttcaagctg tttttatctt tgccgagata
      361 tcttggcaaa atcaatccag caagcaagcc tgtgagaatt tggattggcg aataatacag
      421 agaaaaaata tctgtagtca ctccacttaa aataccgctg gacaatcctg tcagcattcc
      481 aggtacaggc ccaagcaatg caccagcaaa aatcgttccg atagaatcga gatagattgg
      541 caaacgaagc cataaagcaa tcgttcctcc aatataattg atcccaatac acaaagccat
      601 cactgtaagt acgcgagttg ccattttgtt tttattcatt ttgttagccc atctttaacc
      661 tttccaaatc tttcataatc gtttcttctt gtgcatttaa aagaacg
//
LOCUS       DAZKCW010000198          643 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000198 DAZKCW010000000
VERSION     DAZKCW010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.213"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            16..643
                     /locus_tag="ACG84Z_002902"
                     /pseudo
     CDS             16..643
                     /locus_tag="ACG84Z_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
BASE COUNT          228 a          113 c          109 g          193 t
ORIGIN      
        1 aaatgaggac tacatatgcg ttcatcaaaa tatactgaac attatacaga tacttttata
       61 acattcaagg aaattatgag aactgtttct aacatatacc acaattgtgt accagataag
      121 attaaaaacc gaagaaatac tgatcaactg aagtaacgcg atacagtgat tattgcttgt
      181 gttatatggg gcataattaa tggctatact agccaaagag ccacgtatag agcggtttgt
      241 tccgtcttat ttcctaatgg tgactttcct agtaggagtc gattcactcg cttaagttca
      301 aacttagctt acactatcaa gattattcga tactttttca tcaagaagct caccaaaggt
      361 gaactagtcg gaattataga tagttttcct agtccattat gtaaaccagt tagaaataga
      421 caagcaaaac tattgaatca aatagccaaa gttggctata actcaacaaa aaaatcttat
      481 ttttatggtc ttaaaattca tatgatcgtt actaagactg gctttccgat tacttactca
      541 atcacgaatc caggtgtcca tgacgtgaaa gtgttagaga ctttatcgga agaagcgaat
      601 cttcccaata tcctagggga caaaggatat attagccata aaa
//
LOCUS       DAZKCW010000199          640 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000199 DAZKCW010000000
VERSION     DAZKCW010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.214"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..283
                     /locus_tag="ACG84Z_002903"
     CDS             <1..283
                     /locus_tag="ACG84Z_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFP9163659.1"
                     /translation="LIQDDLHHTHRLWLMNKINLYFGHSYVFAFYDYRTNITEVDLVI
                     SNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKEVVKSAFCPEY"
BASE COUNT          218 a           89 c          119 g          214 t
ORIGIN      
        1 tttaatacaa gatgatttac accatacgca tcggttatgg ttaatgaata aaattaatct
       61 gtattttggg cattcttatg tttttgcttt ttatgattac aggacaaata taactgaagt
      121 agatttggtt atttctaatt actacatcga cactggaaaa acgccattac tgttaatgaa
      181 aaatatacct accgaaagaa actggcgttt gttcgagaaa acgatttatc aattgaaaaa
      241 agaaaaagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca aacggaaaaa
      301 tagtttttca tattttgccg tttttgagct aataccgagg gacagctgat tgaacaccat
      361 ttattgagag attgtgaaaa aactgtcctg catcaagtaa taagaacagc caagtaaaaa
      421 cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca agagaacacc
      481 gtttattcgg aaaaagggac tgtgacacta catgtcacag tccctttttg attgaattat
      541 ctcatttgtt ttctaatttt ttctttattt gagaaaatag ttgaactgga taaaaagtac
      601 tggacgtgtc aaaattattt tggatcaaat tagatctatt
//
LOCUS       DAZKCW010000200          630 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000200 DAZKCW010000000
VERSION     DAZKCW010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.215"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>630
                     /locus_tag="ACG84Z_002904"
     rRNA            <1..>630
                     /locus_tag="ACG84Z_002904"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          156 a          144 c          196 g          134 t
ORIGIN      
        1 gaaagccccc ggctcaaccg gggagggtca ttggaaactg ggagacttga gtgcagaaga
       61 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccagtgg
      121 cgaaggcggc tctctggtct gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      181 gattagatac cctggtagtc cacgccgtaa acgatgagtg ctaagtgttg gagggtttcc
      241 gcccttcagt gctgcagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      301 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      361 agcaacgcga agaaccttac caggtcttga catcctttga ccactctaga gatagagctt
      421 ccccttcggg ggcaaagtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg
      481 ttgggttaag tcccgcaacg agcgcaaccc ttattgttag ttgccatcat tcagttgggc
      541 actctagcaa gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat
      601 gccccttatg acctgggcta cacacgtgct
//
LOCUS       DAZKCW010000201          588 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000201 DAZKCW010000000
VERSION     DAZKCW010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.216"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            154..417
                     /locus_tag="ACG84Z_002905"
     CDS             154..417
                     /locus_tag="ACG84Z_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFP9163660.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..>588
                     /locus_tag="ACG84Z_002906"
     CDS             417..>588
                     /locus_tag="ACG84Z_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFP9163661.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRY"
BASE COUNT          223 a           78 c          119 g          168 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtatt
//
LOCUS       DAZKCW010000202          514 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000202 DAZKCW010000000
VERSION     DAZKCW010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.217"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            145..402
                     /locus_tag="ACG84Z_002907"
     CDS             145..402
                     /locus_tag="ACG84Z_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163662.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
BASE COUNT          217 a           65 c           72 g          160 t
ORIGIN      
        1 atttttctgt ccacgttcat attactccaa agttttcctc attccaaaag aaaagcacag
       61 aatacacaaa gaagcgtttt tatttgtata aactatatca aagttctata cttaaattat
      121 caaataaaaa ggacgtgaag ataaatgtca aatttagaaa acaaagaaga aaaagttgta
      181 aacaaaattg tttctgttgt caataaactg gataaagagt tagacgaact tgatacgtta
      241 tctgaaaatc cagaaaaaaa acataaccta aaaaaatggt tagttgaacg aaaggctatt
      301 catgaaatta aaaaagttct tcatgaagct gataaatatg aaaaatatga tgaaaaagaa
      361 cttgataaag aatttaaaga aatcaatgac ttgttactat aattgattta tacgactcat
      421 ttttgagtcg tcagactgca aacaacactc taaatttagg agtttgtcta cagtctgaat
      481 aaattttaaa tttattgtcc ataatgttat tatg
//
LOCUS       DAZKCW010000203          502 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000203 DAZKCW010000000
VERSION     DAZKCW010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.218"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..79
                     /locus_tag="ACG84Z_002908"
     CDS             <1..79
                     /locus_tag="ACG84Z_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFP9163663.1"
                     /translation="RVVYKVDEDEHVVEIYSARTHYESQ"
     gene            156..485
                     /locus_tag="ACG84Z_002909"
     CDS             156..485
                     /locus_tag="ACG84Z_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFP9163664.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
BASE COUNT          189 a           60 c           97 g          156 t
ORIGIN      
        1 ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt cagcaaggac
       61 gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa tgtatttact
      121 aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca agaaaacaag
      181 gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga gtcgaagttg
      241 aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa aaagaatttt
      301 atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat aaagatgaga
      361 ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga gatattgctg
      421 aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca gaaattggct
      481 tatgaaatcg ttccttcaaa ac
//
LOCUS       DAZKCW010000204          500 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000204 DAZKCW010000000
VERSION     DAZKCW010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.219"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          170 a           96 c           58 g          176 t
ORIGIN      
        1 aaaaataaga atgctaaatc actctacaat aacggcgaaa gcacaaaaaa taaaaaaatt
       61 attacgttat taaaaaaaca gatgaaagat caggttttat tagatctcat tctttcatca
      121 cttgaaggga tttaatgaac tactttttcc tctttgtcgt ttttatatat tcgtattcct
      181 tcaaacagta ggatagcctc tttcaatgct tgatatttga actgtccgtt acttaaaaat
      241 ttagatgtgc cgccctcttc ctagaacata ttctttttta ctttttcatt aattgacaga
      301 ccaatcgaac gaaactgtaa atttcgatag gataatgatt ggtcaaactc attcattttc
      361 aagacatctc gattcatatt caagatagga atctttttat caacatcact ttattcgtat
      421 tttcctctac cataaaagct tcacgctcca caaaattgtt ttatacacta ctattcagcc
      481 cattcaacga ccaatgaatt
//
LOCUS       DAZKCW010000205          489 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000205 DAZKCW010000000
VERSION     DAZKCW010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.220"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>489)
                     /locus_tag="ACG84Z_002910"
     CDS             complement(<1..>489)
                     /locus_tag="ACG84Z_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163665.1"
                     /translation="YVFEKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAF
                     SLLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGR
                     YNYKLSVFSIISLAELIFSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGK
                     PFF"
BASE COUNT          186 a           78 c           62 g          163 t
ORIGIN      
        1 aaaaaacggc tttccaaatg atgaaatacc taaatctaac ttattaagaa agttgaaatt
       61 tttatattca ggaaaccatt tattaatttc atgtgcagca cgtaatgcat tccctggagt
      121 tgtcaaagag aaaattaatt ctgctaagct tattattgaa aatactgata acttataatt
      181 atatcgtcca ttgacaatca aatataaact aactatactt gttagaacaa aaaaacaggc
      241 gttgacttgt tcttgattag ttaaaaatat caataaagga atacttaccc aatatatttt
      301 tctatttatt tcttctcctc ttaagagttg aaaaaacgga taaaaagtta gtaaactaaa
      361 tgctactggc cactgatagt tcaaggtggt tgctctccaa ccggtttccc ccattactgt
      421 caatggtatt aaacagtata tagagcaaac caataataaa tttttaacat ttattttctc
      481 aaaaacata
//
LOCUS       DAZKCW010000206          426 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000206 DAZKCW010000000
VERSION     DAZKCW010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.221"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..132)
                     /locus_tag="ACG84Z_002911"
     CDS             complement(<1..132)
                     /locus_tag="ACG84Z_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFP9163666.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          146 a           83 c           83 g          114 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatc
//
LOCUS       DAZKCW010000207          419 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000207 DAZKCW010000000
VERSION     DAZKCW010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.222"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>419
                     /locus_tag="ACG84Z_002912"
     CDS             <1..>419
                     /locus_tag="ACG84Z_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFP9163667.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGEREKQFAYSAHTSCDDNGF"
BASE COUNT          154 a           72 c           87 g          106 t
ORIGIN      
        1 aaaatccccc atttctcaac ttttggaaag aattatgttc gccgatttag agaaacgacg
       61 gtgtttgagg atatttttgc ctatatttta gaacaagcag ttaaagcagg ttttgtaaca
      121 gaggataatt tgtatctgga ttctacccac atcaaagcta acgccaataa acataagttt
      181 acgaaagaaa tgacccatga tgaagcgaaa gcctatcagg atgaattaga agatgagatc
      241 aatcgtcaac gaatagaggc tggaaaacgc ccttttactt tggacttaga aaaggaagtg
      301 aagctgaaag aaagaaaaat aagtaaagct gatccggaaa gcggctacta cgtcaaaggc
      361 gaacgagaaa aacaatttgc ttattctgcc catacttcat gcgacgacaa tggatttat
//
LOCUS       DAZKCW010000208          414 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000208 DAZKCW010000000
VERSION     DAZKCW010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.223"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          140 a           55 c           60 g          159 t
ORIGIN      
        1 tagatataat acaaaaaggc aaagatattt tcaaaacatt ttttcttgat gtgatatcct
       61 tgtctttttt gtaatgtttt taacttattg cttttgcaaa atttatttac ctgttttctg
      121 gatcaacgat agtgtatatt atgctatcct tgtttggatt ttaggacgtt taaagaggca
      181 cttttttaca taacttaatc catagacctt ttaagcatgc tgtgagataa taataaagaa
      241 gagtttaaag cgcaccccaa accacttccc cataagtgta ttacgcttta aactctttta
      301 tatttgaatt cactaagaag cataccatat ttttgaaaaa aagtgagaaa aaaggcttat
      361 aattaggatt tagagtaatt aattagatgt ttattttata ggactgatac tata
//
LOCUS       DAZKCW010000209          403 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.224, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000209 DAZKCW010000000
VERSION     DAZKCW010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.224"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          163 a           52 c           64 g          124 t
ORIGIN      
        1 gatgaaagcg catactttta agaggggttg tatgtaattt taatacctat accaatttaa
       61 agaggatttt tcagattttc acttacaaat ttataaaaaa acaatataat tgatactttg
      121 attttgcgaa cattttgcct ttccgcctaa ttcagcttta ataccttgat tatatcagta
      181 actaatcgcc tttttagcta atttaagcat caaataatta tccttaatca gggtaaaaaa
      241 taacgaataa atggattttt ggaataggta aaaactagat cggtttctga cgaaaaataa
      301 cattaaaaag gaaatataaa ataacatgga gcgtgggagg aataaagaaa ttttacacac
      361 aaggggcgta ggaatgtaaa gaaacttaac acaaaacaaa agt
//
LOCUS       DAZKCW010000210          393 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.225, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000210 DAZKCW010000000
VERSION     DAZKCW010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.225"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>393)
                     /locus_tag="ACG84Z_002913"
     CDS             complement(<1..>393)
                     /locus_tag="ACG84Z_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163668.1"
                     /translation="NQKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEH
                     IIKHEAKIGSQWVNLPYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQ
                     VNANGLVQISGVKGVADIKVSTSYTVTT"
BASE COUNT          106 a           76 c           58 g          153 t
ORIGIN      
        1 tagtcgttac tgtataactt gtgcttactt taatatcagc aactcctttg actccgctta
       61 tttgtaccaa tccattagca ttcacctgct cctttacagg ttgatgattt atttctacat
      121 tcgttcctaa ataagcatat acaggaagtg tgattacttg gctcttctca ttagttactc
      181 tatatatgat agaactacca gttgttttat aaggaaggtt tacccattga ctgccaatct
      241 ttgcttcgtg ttttattata tgctccttat tctccaatga agcgatagga gaataatcat
      301 ataaaaaata atccattcct ttagtggtat acgcctctac tgtttctttg tttacaacaa
      361 tatgtcccgg ctgagaaatt attttttgat tga
//
LOCUS       DAZKCW010000211          382 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.226, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000211 DAZKCW010000000
VERSION     DAZKCW010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.226"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>382
                     /locus_tag="ACG84Z_002914"
     CDS             <1..>382
                     /locus_tag="ACG84Z_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFP9163669.1"
                     /translation="FDITQTQLKPEDYPKIFPNRVFDFQLDKKGQSELQAGIQAVANN
                     IGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNTRNTPTQHLATSIHELAHA
                     RMHKFSELDTATKELQAEMTSYIV"
BASE COUNT          140 a           68 c           76 g           98 t
ORIGIN      
        1 tgtttgatat cacacaaaca cagttaaaac ctgaagacta tccgaaaatc tttccgaacc
       61 gtgtctttga ttttcaattg gataaaaaag gacagtcaga acttcaagct gggattcaag
      121 cggtagccaa caatattgga atacaaattc gagatatgac agaaagtgaa gtctatcaaa
      181 gagaattagg acaagcacgt ggggcgtatg ttcgtaacga atttactggc gaagaagaaa
      241 tcgtcatgaa tactcgaaat actcctacgc agcatttagc tacaagtatt catgaattag
      301 cccatgcaag aatgcacaaa ttttcagaat tagataccgc aactaaagaa ttgcaggcag
      361 aaatgacttc ttatattgtg tg
//
LOCUS       DAZKCW010000212          376 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.227, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000212 DAZKCW010000000
VERSION     DAZKCW010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.227"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(143..304)
                     /locus_tag="ACG84Z_002915"
     CDS             complement(143..304)
                     /locus_tag="ACG84Z_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFP9163670.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
BASE COUNT          127 a           71 c           41 g          137 t
ORIGIN      
        1 cattgcttga tttcattatt gttaaacaag aatacaagca agaaagaact atagttaata
       61 tgataaaaat tattaaagtt ctatttttct ttcttgtaat atatgctata gcatttttta
      121 tcactttcct aactactcct ctctattttc ttactccata actaattgca tccactggac
      181 aagcattttt acatcgtcca catctgatac actccagatg attgcaattc tcaactgaat
      241 ctttattcat ttggcaaact tttttacatt ttccacaatt aatacactta tccttatcct
      301 gaatcggcta cactagacta gacagaaaaa ataaggtgtg tagaataata aaaaacacac
      361 tggaggattt ttcatg
//
LOCUS       DAZKCW010000213          361 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.228, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000213 DAZKCW010000000
VERSION     DAZKCW010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.228"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
BASE COUNT          134 a           55 c           40 g          132 t
ORIGIN      
        1 tttttcactt tctaagtaag aaacaaaaaa aacttcatgg ccactatcta ttaatccttt
       61 tgcaattttt gaggccacga tactagctcc tcccattgag aaagctggag atagtatagc
      121 tattttcaaa taaaacactc ctttatagaa agctattttt ttaaaatata cctaaaaaga
      181 atttttttga taaatgtaaa ttcttctctt ctaaaatata ataacaaata taatatcgat
      241 gttgttacta tagttattaa ggttttagtt ataaattgaa ggaacgtact gcctccattt
      301 gctaaatatt catttaatag aaaaacgact attgccgaaa ttattaattc tataaaactt
      361 c
//
LOCUS       DAZKCW010000214          341 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.229, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000214 DAZKCW010000000
VERSION     DAZKCW010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.229"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>341
                     /locus_tag="ACG84Z_002916"
     CDS             <1..>341
                     /locus_tag="ACG84Z_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFP9163671.1"
                     /translation="EATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEP
                     DAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNR
                     SDADKYEPTVEG"
BASE COUNT          141 a           50 c           76 g           74 t
ORIGIN      
        1 gaagcaactc aaccaattac agcagatgat acagaatttg tatcaagtgc aacaaaactg
       61 gatgataaat ctgacgctga caaatataat cctgaaggtc aaaaagtgac tacagaattg
      121 aataaggaac cagacgcatt tgagggaatt aagaacaaag aagatttacc aaaagatact
      181 aagtatactt ggaaagaaaa agtagatgtt agcgcagctg gaaataaaaa agggactgtt
      241 gtagtgacat atccagatgg atcatctgat gaagttgaag tagatgttac agtgacagac
      301 aatcgttctg acgccgataa atatgagcca acagtagaag g
//
LOCUS       DAZKCW010000215          339 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.230, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000215 DAZKCW010000000
VERSION     DAZKCW010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.230"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>339
                     /locus_tag="ACG84Z_002917"
     CDS             <1..>339
                     /locus_tag="ACG84Z_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9163672.1"
                     /translation="EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQ
                     TLPAYKRTNDTLETTIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVN
                     AFKSRALNDK"
BASE COUNT          129 a           61 c           56 g           93 t
ORIGIN      
        1 acgaaaaata tgatcgcact ggttttaatt caggtaattc gagaaacggt tcttactttc
       61 gatcaatcaa aaccgaatat ggtgaattaa cattggaaat acctagagat cgtaatggtg
      121 agtttaaaca acaaacttta ccagcctaca aaagaacaaa cgatacattg gaaaccacta
      181 ttatccattt attcgaaaaa ggtgttacga tgtctgaaat tgctgatttg atcgaaaaaa
      241 tgtacggtca tcactatact ccacaaacca tgtccaacat gactaaagtt ctgactgaag
      301 aagtaaatgc ctttaaatcc agagccttaa atgataagt
//
LOCUS       DAZKCW010000216          321 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.231, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000216 DAZKCW010000000
VERSION     DAZKCW010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.231"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>321)
                     /locus_tag="ACG84Z_002918"
     rRNA            complement(<1..>321)
                     /locus_tag="ACG84Z_002918"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           63 a           96 c           74 g           88 t
ORIGIN      
        1 aaatccggac aacgcttgcc acctacgtat taccgcggct gctggcacgt agttagccgt
       61 ggctttctgg ttagataccg tcaagggatg aacagttact ctcatccttg ttcttctcta
      121 acaacagagt tttacgatcc gaaaaccttc ttcactcacg cggcgttgct cggtcagact
      181 ttcgtccatt gccgaagatt ccctactgct gcctcccgta ggagtttggg ccgtgtctca
      241 gtcccaatgt ggccgatcac cctctcaggt cggctatgca tcgtggcctt ggtgagccgt
      301 tacctcacca actagctaat g
//
LOCUS       DAZKCW010000217          320 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.232, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000217 DAZKCW010000000
VERSION     DAZKCW010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.232"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            99..>320
                     /locus_tag="ACG84Z_002919"
     CDS             99..>320
                     /locus_tag="ACG84Z_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163673.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQYNGNILLKNEDNKRFFIKK"
BASE COUNT          129 a           31 c           51 g          109 t
ORIGIN      
        1 tttattaaaa ggcttctttt gttcgatcag ttatagtcga acgagagaag tttattcttt
       61 gattaaaata aacaaaagta acttattgag gtgaaatgat gcaaactttt ttaactaaaa
      121 catctttcaa aaaagtagtt ttattagatt atttgttaga aaaagacaat tggtgtgcaa
      181 tggaagaact tagaaattta cttaatgtta cggagaagtc agtcttacac tatatagaag
      241 aactagagga tttatttaag caatataatg gtaatatcct tctgaaaaat gaagataata
      301 aacgattttt cataaaaaaa
//
LOCUS       DAZKCW010000218          303 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.233, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000218 DAZKCW010000000
VERSION     DAZKCW010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.233"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACG84Z_002920"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACG84Z_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFP9163674.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           95 a           45 c           50 g          113 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atg
//
LOCUS       DAZKCW010000219          273 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.234, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000219 DAZKCW010000000
VERSION     DAZKCW010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.234"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>273
                     /locus_tag="ACG84Z_002921"
     CDS             <1..>273
                     /locus_tag="ACG84Z_002921"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFP9163675.1"
                     /translation="GGFVPSRYIKKEKEQLKKVLKKEKPDVIIFNTFIPSVLFSEFLK
                     YEFPTVKLITWMHSDPDYSLNHIAKFYKKEYRKSFERVDSIVCLSQ"
BASE COUNT          105 a           40 c           40 g           88 t
ORIGIN      
        1 ttggaggctt tgttcctagt agatatataa aaaaagaaaa agaacaacta aaaaaagttc
       61 taaagaaaga aaaacctgat gtcatcatat tcaatacttt tatacctagt gtactattct
      121 ccgaattcct aaagtatgaa tttccaacag tgaaattaat tacttggatg cactctgatc
      181 ctgattacag cttaaatcat attgctaaat tttataaaaa agaatataga aaaagttttg
      241 aacgcgtgga ttccattgtt tgtctttcgc aag
//
LOCUS       DAZKCW010000220          258 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.denovo.236, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000220 DAZKCW010000000
VERSION     DAZKCW010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.denovo.236"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            163..>258
                     /gene="rrf"
                     /locus_tag="ACG84Z_002922"
     rRNA            163..>258
                     /gene="rrf"
                     /locus_tag="ACG84Z_002922"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT           89 a           44 c           65 g           60 t
ORIGIN      
        1 taggtcagga gtggaagtac agtgatgtat ggagcggact gatactaatc gatcgaggac
       61 ttaaccaata ggttaaaaga aaagaactcg gaaaaaaact tatgtgactt caaatccagt
      121 tttgagtgaa caaaatttac tcaataaaag ataacaccac agtgtggtgg cgatagcgag
      181 aaggatacac ctgtaaccat gccgaacaca gaagttaagc ttcttagcgc cgattgtagt
      241 gaggggttgc cccttgtg
//
LOCUS       DAZKCW010000221        14365 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.058, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000221 DAZKCW010000000
VERSION     DAZKCW010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14365
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.058"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..678
                     /locus_tag="ACG84Z_002923"
     CDS             <1..678
                     /locus_tag="ACG84Z_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFP9163676.1"
                     /translation="IVLFFWNHFKAEHEAMLKQAQDEPAIDEIYHFDFLEAKELGLKH
                     NSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKRDVTTNYFILPHRGNE
                     QPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQKKLVTDNQAIAHYHFY
                     RPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKRFITNDSTIYEQYEYD
                     LSSVENK"
     gene            complement(828..1769)
                     /locus_tag="ACG84Z_002924"
     CDS             complement(828..1769)
                     /locus_tag="ACG84Z_002924"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFP9163677.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1895..3015
                     /locus_tag="ACG84Z_002925"
                     /pseudo
     CDS             1895..3015
                     /locus_tag="ACG84Z_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            3273..4775
                     /gene="eat(A)"
                     /locus_tag="ACG84Z_002926"
     CDS             3273..4775
                     /gene="eat(A)"
                     /locus_tag="ACG84Z_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFP9163678.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4842..5369
                     /locus_tag="ACG84Z_002927"
     CDS             4842..5369
                     /locus_tag="ACG84Z_002927"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFP9163679.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            5580..6641
                     /locus_tag="ACG84Z_002928"
     CDS             5580..6641
                     /locus_tag="ACG84Z_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFP9163680.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6644..7540
                     /gene="murQ"
                     /locus_tag="ACG84Z_002929"
     CDS             6644..7540
                     /gene="murQ"
                     /locus_tag="ACG84Z_002929"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFP9163681.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7554..9536
                     /locus_tag="ACG84Z_002930"
     CDS             7554..9536
                     /locus_tag="ACG84Z_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFP9163682.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9601..10047)
                     /gene="nrdI"
                     /locus_tag="ACG84Z_002931"
     CDS             complement(9601..10047)
                     /gene="nrdI"
                     /locus_tag="ACG84Z_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFP9163683.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            10258..11682
                     /locus_tag="ACG84Z_002932"
     CDS             10258..11682
                     /locus_tag="ACG84Z_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFP9163684.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(11863..12636)
                     /locus_tag="ACG84Z_002933"
     CDS             complement(11863..12636)
                     /locus_tag="ACG84Z_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFP9163685.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12633..13538)
                     /locus_tag="ACG84Z_002934"
     CDS             complement(12633..13538)
                     /locus_tag="ACG84Z_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFP9163686.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(13692..14012)
                     /locus_tag="ACG84Z_002935"
     CDS             complement(13692..14012)
                     /locus_tag="ACG84Z_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFP9163687.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         4590 a         2563 c         3042 g         4170 t
ORIGIN      
        1 attgtgttat ttttttggaa tcacttcaaa gcagaacacg aggcgatgct gaagcaggca
       61 caagatgaac cggcaatcga tgagatttat cattttgatt ttttggaagc aaaagaactt
      121 gggctgaaac ataatagttc attttattcg aaacatatga atttttcttc tagcgaacca
      181 aagacggatc tattttttgg tgcaacgaat aatgggagaa aagaacgagc agaaagctat
      241 aagcaggaat ttataaaaag agatgttacg accaactatt tcattcttcc acatcgaggg
      301 aatgaacaac ctggatatct tacttatgaa gagtacctga aaaaaacagg ggaatcgcgc
      361 gggattctgg aactgttgcg ggagggtcag caaggagtga ctttgcggac atttgaatcc
      421 atgtattttc aaaagaaact agtgacggat aatcaagcga ttgctcatta tcatttttat
      481 cgtcctgaaa atattttttt gcttcgagaa cgtgatttag atgaattacc ggaatttctg
      541 catacaccat ttaagccaat cctatcagag ctattggaat tttatgatgc agaaaattgg
      601 gcaaaacgat ttatcactaa cgattccact atttatgagc aatacgaata tgacctctcc
      661 tctgttgaaa acaaataaaa aacctacatt ttgaagagat tatgtactga aacaaacaag
      721 cacaattctt atggcatcat gagagttgtg ttttcttttt gatcttttat tgggcttaaa
      781 aaaagagaac cagctgctga ttcagctgat tctcatcaga gagcctttta ttctgcgcca
      841 aggattcctt cttttgcatg gactaattgg gtcaaaaagg cacaatatgg tgtagcaata
      901 tcatattttt gtccttttcg ccaaatggca ccattgatgt agtcgatttc agtcaaacga
      961 tggtttttga tcaggtcttg gtacatagat gggtaatgca acccgatgtt gtcaggatca
     1021 taagtagaag caatatgttg gtacacttct tcttgatcta gtatgattcc ttcttttgct
     1081 gcgatagaag caaattcaga tacgattgtt cgaaccatgc tctctgccgc tttttgcgcg
     1141 cctagttcag caatattaca atccaaaatc gtgcataaac cattcaatgt tccatttaca
     1201 caagcttttc gccaaatgga ataacgaacg ttatggctat agatcggatt taaatttgct
     1261 tcttgaaaga cttctacaac tttttttgta aatgcttcgc cttctggttc caagttctct
     1321 agttcgattt ctccatcacc taacaatgtg acttttccgg gaccagctag accagctgtc
     1381 cacatcgtga tcccaaataa gatatttttc tttggcacat atttttccag tacatcttca
     1441 tgacctaatc catttagtaa acacaaaaca taagtattgt cagtaataat ggattggatc
     1501 gaacaaaaca tatcatctaa ttgattggct tttgttaatg ctacgatcaa gtccacgtgt
     1561 tcgttgcttt cgatgatttc ttctggtgaa tagattggca gttttgcgac cacttcttta
     1621 ccgttaaagt cagcaatcaa cccatttgta cgaatggctt caatgtgagc aggccaacga
     1681 tcgatcaaga ggacctcatt tccgctttga tgtagcatca atccgattcg gctgcccatt
     1741 gctccggccc cagctattgc gattttcatg ttttttctct cctttattca atgagttccc
     1801 ttttagtata tagaaaaatg gaagaaaata gcattgtttt gtttgaaaaa aatgaaaaaa
     1861 agtgtcttac ttaagaagaa agtgagggat acagatggat attttggcgg caattgattc
     1921 atttaaagga agtgcttctt catttgaact aaatcaggca gttctaaatg gctgggaaga
     1981 tcgtaaagga agaaaaatca atgtgccgat tgcagatggc ggagaaaata ctgcagaagc
     2041 aatctattac gcgctcaggg gaacatggcg taccattgat gggatggatc tcttattccg
     2101 tcagcgaaaa atcagctatt tattgacaac ttggcaagga aaaaacaccg cagtcatcga
     2161 atctgcacaa gcattggggt tagatctact tgataaacca acggatcaaa ctatccgact
     2221 tgcttccagt tatgccttag gagaacttat taaagatgca ctgcttcaag aagtagaaca
     2281 aattattgtc actttaggag gaagcgggtg tagcgatggt ggtctaggat tactccaatc
     2341 cttgggtgct tctttagaag ggtacacaga aggaaatcct ttattatcta ctaaaaaact
     2401 tcattttgat cgaagaaacg ttcttgtttc taaagtaaaa ttgattatcg ctgcagatgt
     2461 taccaatcca tatacaggtc aacaaggagc tgcttggcaa tttggaagac aaaaaggagg
     2521 aatagatacg acgctagctt tcttagataa acaagcagga aagattgctc agcaaataaa
     2581 agatttctgg gaggtggatt tagatgatat tccaggaagt ggagcagcag gcggtattgg
     2641 tggagccctt ttttgttggg agcgaagatg gtttctggtt tcgatttagt cagccaaatc
     2701 actggattgg aaaaaaagat cgaacaagca gatgtcatca ttacaggaga agggcggatc
     2761 gatcagcaaa cgatccacgg aaaagttcca tacggtgtag cagtgcttgc aaaaaaatat
     2821 cgaaaaccaa taatcgctat ttgcggaagt agagaccaag agctagaagg actttctgat
     2881 tttctcccaa ttgtcttaag tattcatttg ggtccaatag gtttagaaga agcaatggaa
     2941 cacaggcaaa cattagaaaa aacaaaaatc ttaggacaga cacttagcag atttttcacc
     3001 atcctcccga agtagttgac aaaatcattt tctttatgct atcgtaattt caaatatagg
     3061 acaaagtgag ggatccgtgc attgaaaaat taagtcgatt gatgaaagct gcattcagac
     3121 tgtaccttgt ggagacaagg aagcagtgtg cagattttcg ggattggctt ggttttttcg
     3181 atgtatgggt ctttttgtgt gtatccaacc cttgcatcct ctttagccag ttctgaaaat
     3241 aggactggtc tttttttacg aggtgatgga aaatgtctaa aatcgaaata aaaaatctga
     3301 cattcggcta cgacagccaa ggcacattat tatttgaaca agcaaatcta aattttgaca
     3361 cacaatggaa actaggactt atcggacgaa acggtcgagg aaagacaact ttactgaata
     3421 ttctacaaaa caaactacct tatcaagggc aagtaatcca tcagcaagaa tttgcctatt
     3481 tcccgcaaca gacaaaagat aaagaacgtt taacctatta cgtgttaaat gatattacgg
     3541 attttgagat atgggaaatc gaaagagagc tccaattgat gcaaacagat cctgaaatct
     3601 tatggagaga attcagcaca ctatcggggg gagagaagac aaaagtccta ctggcacttt
     3661 tatttgtgga tgacactcat ttcccgttaa tcgatgaacc aacgaatcat ttggatatct
     3721 ctggtagaaa acaagtagcg gcttatttga aaaagaaaaa acaaggcttc atcgtggtca
     3781 gccatgaccg gggatttatc gatgaagtag tggaccatgt tttagcaatc gaaaaaagtc
     3841 aactggaact ttatcaaggg aatttctcta tctatgaaga acagaaaaaa cttcgtgatg
     3901 aatttgaaat ggctcaaaat gaaaaattga aaaaagaagt cagtaggcta aagaaaacag
     3961 cagctgaaaa agccgaatgg tctcgttccc gagaaggaga taaaacaaag aaacaagtcg
     4021 gattcatcga tactgaatct agacgagtga ataaaggagc agtgggtgct gatgctgcac
     4081 ggacgatgaa acgatccaaa gcaatcgtga atcggatgga gacccagatc agcgagaaag
     4141 aaaaactatt aaaagatatc gaatatatcg attctttgac gatgaatagc caagcgtctc
     4201 accataagcg acttttaagc gtagaagatc ttcaattagg gtatgaaaat ctgttattcg
     4261 agccaattca ttttacaatc gagcctcatc agcgggtggc gatttcaggt cctaacggtg
     4321 caggaaagtc atccattatc cattatcttc tgggggcatt caacggcaag gttataggag
     4381 aaaaatacca gccaaaacat ctgagcatta gttatgcaag ccaaaattat gaagacaatc
     4441 gaggaacgtt ggcggaattt gcagagaaaa accaagtaga ctaccaagca tttttgaaca
     4501 acctccgaaa gcttgggatg gaaagagatg tttttcataa caagatcgag cagatgagta
     4561 tgggccaacg gaaaaaagtg gaattggcta aatctttatc acagccagct gaactatata
     4621 catgggatga accattgaat tatttggatg tcttcaatca agaacaatta gaacaactga
     4681 tcttgaacgt gaaacctgcc atgttactag tggaacatga tcaaaccttc ctggataaag
     4741 tatctactga gattatttct cttgagagaa tctaaccctt gtaatctcaa gaacaacaag
     4801 gtatggttaa ggggaacttt gccaacgaag gagagaatca catgctttat gtaacgagac
     4861 acggagaaac aacttggaac gcacaaggat tagtttgcgg acgggcagat gtgccgctga
     4921 ctgaaaaagg acagatgcag gcacagaaac tagcagaaaa ggtagtagat ttgcctgttc
     4981 caatcacgaa aatcatccat tcccctcttc aacgagcaag agatacagca caagcagttg
     5041 ctgatcgtct cagcttgccg ctgaccgttg atgaacgatt ggtagaaatg gattttgggg
     5101 attatgatgg actgccaagc aaagatgaga actttcaaaa agcacgttta gcgttcgctg
     5161 tacgattccc aaatggggag tcagtcttag atgtgtatgc acggatcgtt cctttattga
     5221 aagaatgcat cgaagacgaa gaaaatgtct atctgttagt ttgccataat gccttgataa
     5281 gagtgatcaa tgcttatttt catccgatgc ctaatgaggg gttctttaca ttcatggtag
     5341 ataatacaga attggtttct tatgagtaat tatgtttttg tgttatttaa ataaaatatt
     5401 tcaaggcact gcttttgctt agcagtgcct tttttaggtt atgacaattc ttttgataat
     5461 ataaactcaa cctttagaaa tgaaatttaa ttattttaat aaaagtattg aaattttgtt
     5521 tctttagata tatactctag tcatagaaat gaagacggat acagaaaaag agggataata
     5581 tgtttggctt ttcaatattt atgaacgatt ctttgtcaga agagaagaaa cagtatatcc
     5641 gccaaatggc atccaatggc tttgtcggta ttttcacttc catgcatata ccagaagatg
     5701 atgtttcggc atatcaaaag cgattgatcg aactaggaag cgaagcgaaa aagaataaac
     5761 tagaattgat ggtcgatatt tcaggagagg cattggaacg agcgggtttt tcattagaag
     5821 atctaacgcc tttgaaagca attggtgtaa caggtttaag aatggattat catatttcca
     5881 atcagcagat tgccgactgg tcacatcaat tgaaaatcag tttgaatgct agcacgatca
     5941 cgcctaaaga tatcgatgaa ttgaaagaag cagaagctga tttctcacag attgaagctt
     6001 ggcataatta ttatccacgt cccgaaacag ggctggacaa agaatggtat cagaaaaaaa
     6061 atcaatggct caaaattcaa ggtctccttg tccaaggttt tgtaccagga gatacagagt
     6121 tgagaggccc actatatcaa ggattgccaa ctttggaaga acatcgaggg atccatcctc
     6181 ttgcaggcgc tctagatcta ttagcaagta acacggatat tgtttacatc ggagatgcag
     6241 gtctgtcaga aaacgttcag gagcaatttg cttctttcca aaaagaacag acagtcttgc
     6301 tccatacgga acctgtagat gaagaatttt acgaatatat attagggaag catacgaatc
     6361 ggcaagacga tgcaagagat gtcatacgaa gcgtagatgc acgttttcga gagattccgc
     6421 ctatcccagc aagaaataca gctacgcgta tgaaagggtc tattacttta gataacgaaa
     6481 agtatttgcg ctatatgggt gagatccaat taaccaaata tgatttgcca gcggatgaaa
     6541 aagtgaatgt agtagctaaa gttatcaaag aagagctacc attgatcaac caaatcaaag
     6601 ctggtatgaa ctatcaattt ataagaaaag aaggaagata aaaatgagca aaatcaattt
     6661 agagaaccta acaacggaac gcagaaacca agaaactttt ggattagatg agatgagtat
     6721 ttctcaagcc gttcaactaa tgaacaaaga agatcagaaa gtggccgctg cggttgaaaa
     6781 agaactgaca agtatcgaac cagtgattgc taacacgatt gagtccttta aaaaaggtgg
     6841 acgtctgatt tatatgggag ccggaacaag tggaagacta ggtgtgttag atgctgctga
     6901 atgcgtaccg acattcggtg tagaaccgga aatggtcata ggtctaattg ctggtggaga
     6961 agaagcaatg actgtagctg tcgaaggggc cgaagattct tatgagctag ggcaagaaga
     7021 tctaatcaag ctgaatttga caaaaaatga tatagttatt ggtatcgcag ctagcggtcg
     7081 tacaccatat gtgatcggtg gattagatta cgcaaaatcg atcggtgctg tcacaggaac
     7141 gatttcttgc aataaacaag ccgaaatcag taaacacgcg gatttcccaa tcgaagtcga
     7201 tgcaggtcca gaatttttga caggctctac tcgattgaag tcaggaacag cacaaaaact
     7261 tatcttgaat atgatttcta ctatcagtat gattggtata ggtaaagtat tcaataactt
     7321 gatggtcgat gtcaaaccaa caaatgaaaa actaatcgaa cgctcaaaac gaatcatcat
     7381 gcaagcgaca gaagctgatt acgaaacagc tgaaaagtac tttgaagaag cagatcaaaa
     7441 tgttaagctg gctatcgtca tgattttgac aaatagtgat aaagaggaag ctcaagcaaa
     7501 attagctgaa gcaaacggat ttgtaaaagg gaccttatga gggggaaaag accatggcaa
     7561 aaaacgaact gactttggaa gaactggcaa aacaaattta taaaggggca ggcggcatgg
     7621 gcaatgtaga aagcattgtc cactgcatga ctcgtgtgcg tatgaagatc atcaatgatg
     7681 atcttgtaaa tgtctctgaa ttaaaagcga ttccaggagt gcttggtgta gtagaagatg
     7741 aacagcttca agtcatcatc ggacctggga aagtgaacaa agtagcacag caaatggttg
     7801 atttggcagg cgtgaaatta ggagaaaaac tttcttctgt aagtacagct acagcaaatt
     7861 catcagcatc tggaaaagac cgtgtaaacg aacgggcaca agaaatgaaa gcggcacaaa
     7921 aatcgaaaca aaaaccatct aaaatcaaat cggtattaaa agacatttct aatatctttg
     7981 tgccaatgat tcctgcattt gtcggtactg ggatcgtggc agggattgcc gcagttttag
     8041 caaacttagt cacagccgga acacttgatg cagcaacatg gcaacaatat atcgatgtga
     8101 tgaacatctt gaaaaacggg atgtttagct acctagttat ctatacaggt atcaatgctg
     8161 cacaagtttt tggtgcaaca ccaactcttg gtggagttat cggggccgtt gtgatgctga
     8221 cagggatgaa tccggaagca ccactgaaaa acttatttac tggtgaagct cttgcagctg
     8281 gacaaggtgg gatcctaggt gtcatcttcg ctgtttggct attgtcaatc gttgagaaaa
     8341 aactgcataa agtagtacct gatgcggtag atatcatcgt tacaccaact ctttcattga
     8401 ttgccatcgg tctgattgaa attttcttca tcatgccttt agcaggtttc atttctgatg
     8461 gcatggtcgg tgggatcaac tgggtacttg gcgttggtgg agcatttgcc ggcttcgttc
     8521 taggcacatt attcttgccg atggttatgt tcggactgca tcaaattttg actccaatcc
     8581 atgtgcaaat gattgatgaa actggtcgta cgctattgct tccaattctt gcgatggctg
     8641 gtgcaggaca agtgggtgca gcattggcat tatggattcg ctgcaaaaaa gataaagaat
     8701 taacagaaat gatcaaagga gctttaccag tcgggatcct aggaatcggc gaaccattga
     8761 tttacggagt aacattacct ctaggacgcc catttattac tgcttgtatc ggtggaggta
     8821 tcggcggggc agtgatcgga atgatcggaa atgtcggggc tatcgctatt ggaccttcag
     8881 gagccgcttt gatcccattg atctctgacg gtaaatggtt aggctacatc cttggattat
     8941 tggcagctta tgctggtggc ttcgttgcta cattcttctt cggtattcct aaagaccgtt
     9001 tagaaaaaga agaattagcg actgaaacag ccacagtaaa tgaagtgcct gaaaaagtag
     9061 tacctcaaac ttcagctgaa agtgtgacta tcctctcatc agttgctgac ggaacagttg
     9121 tttctttaga taaagcaagt gatccagttt ttgcacaaaa gatgatgggt gaaggctact
     9181 ttgtagaacc agaaaacgga catatctatt ctccagttac tggggtagtc agctctgtct
     9241 tcccaacgaa acacgctatt gggatcacaa cgccaaatgg tttagaaatc ttgcttcata
     9301 tgggaatcaa cacagttgac ttaggcggta cgccatttga tgtgaaagta acagaagggc
     9361 agcaagtgac acctgatacg cttgtagcag aagctgactt agaagcgatc aaagcagcag
     9421 gcaaagaaac atccatgatc gtcttggtaa ccaatatgga tcgtgtaaaa aactttgtct
     9481 tggaaaaaac aggtaaagca aaagcaaaag cacctgtgat ggatgtcaaa gcttaatatg
     9541 atagaaacaa tagaaacgaa agaagaaact gaaatctatt tttcagcttc ttctttttta
     9601 ttatttattg ttttctgcta aaatctgata aattcgtgtc acatcagatg gtgttccccg
     9661 taattcataa tctgccaaga aaggaaagcc aaatgtttgt gcatattgtt tggctgttag
     9721 acaatactga ttattgaagt ttttatttcc gctaccgact acaccaagac aaagtttatg
     9781 attgtcttca tgttccagat attcacgcat cgtttcggtc aagatttctg tatcaccgtt
     9841 atctaaacca tttccgccgt ctaaataagt aggaacgaaa gtaaaaaatg gttctgtttc
     9901 tttcgtaaaa tcactatttt catggatttc ttttaaagta acttcaggat tgacaggatc
     9961 ttctgcatgc attttttcag catattctgc tagatgtttg gcaaaggcac gcgtatttcc
    10021 tgaaatcgat atatataaaa tgttcatgga tcatcctcca attctttcct tttagtatag
    10081 catctttttt aagttttttg gtggtgtaat ttggaaaggg actaggcgct ttgcttgtat
    10141 aatgagaaaa aagccggtag aattatattt ctattaaagt ttttattaat taagtaaaaa
    10201 taaaaaaggt ttgttatact ttttgataaa agcggtttta ttttggagga tgcttacatg
    10261 gatacagagc aacagaaaaa aggaattggt ttaattccac ttgctgcctt agtaattggt
    10321 tcagcgattg gaggtggcgt atttggtatt atgacggaca tctccggatc ggctggcggc
    10381 ccagctattt tcagttgggt actcgtagga acagcaatgt tgatgctctc cttgtcgatc
    10441 aataatatca ataaaaaacg tccagattta aaaggcggga tctttagtta cgcagaagaa
    10501 ggttttggcc gtttcgctgg ttttatcagc ggttggggtt actggctcac atgctggtta
    10561 ggcaacgtag cttttgcaac attgttgatg agcgcattag gatatttctt cccagtattt
    10621 gaaggtgggc aaaatctggc atcgatcgtg atgagtacag tctttttatg gggatatgca
    10681 tggctagtga atcggggagt cgaaaatgct agtttcgtca atgctatcgt cacattctgt
    10741 aaattagtgc cattattttt atttattgta gtagctatca gcacgttttc gatccaacaa
    10801 ttcattgata acttttctag cgacattata ttgaatgcga atggacagcc gatcccgttt
    10861 tccagtcaag tattgagttg catcatggtg atgctttggg tatttgttgg tattgaagga
    10921 gcctctgtcg taggttcacg agcaaaaaaa caatcagatg ttgggaaagc aacgattcta
    10981 gggatattcg gcttgattat tatttacgtc ttggtttcca tgcttccata tgggacaatg
    11041 acgatgaatc agctgcaaac gatcaaggcg cagcctgcta tgggctatgt gtttgaaatg
    11101 atggttggta aatggggagc agtcgtgatc aacggcggtt tgatcatttc tttagttggt
    11161 gtttggctct catggacgat cttaccgatt gaaacaatgg gaaacatggc tgaagacgga
    11221 cttttgccta aagcatgggg aaaactcaac aaaaatgggg caccaactta tgctatcgta
    11281 ttgacgacgt tatgtacgaa tgtcttttta ctttcattat tattcactga cagtgcttat
    11341 aactttgctt acacacttgg tacagcagct attttcttca cgtggctttt cttaggattg
    11401 taccaaatga aactttctta tcagcggaaa gaatgggtcc aatttttagt agggctttta
    11461 gcaagtgcct ttcaagtatg ggctatgcta gtcgtagcct ttaatgaagt aatgcttgtt
    11521 cttgttcttt tcttgccagg catttatttt tacctcaaag cacgtaagga gcaaaacgag
    11581 cctgtacaac atatccactt agataagatt ttacttatag gtgtgacgat ggtcggagtg
    11641 attgcaatgg ttttatttgc cactgggatg cttcacgtat agaagtataa aagaagtata
    11701 aagagaggtt gtgagcctgt cgtttattca aaaacatact aggaaaggag ctgtgacaca
    11761 aatgttgtca cagctccttt ttcagaataa acggtgttta agagacagcc aatcggcaat
    11821 aaggctgaac gtctctttca cagcctcttt tttgatgagt catcatacat tttttcgctt
    11881 aaatacgaga tatcctaatg ctaagaacaa aacgatgtaa gctaaattac cgaatagcat
    11941 ttgattagta gaaagatgag tcaattgctt catgatctct tcgtttccaa tttggttttg
    12001 cagattcaac atactgatcg gattccattt gatccactcc catttttgga tgagtgcaat
    12061 aaggatacca gatatgattg acgaagcaaa ataaaagacg attcctgctg agatggatgc
    12121 gccggaacta ttgataaagc aagcaatcat caacactaaa cttaaaatca gccataaacc
    12181 gatataacta cccaaagtat aagtgaacaa gctttggatc agtgtttgac cagtagaaac
    12241 cttctccgtg aaggaaatcg aagggaaaag aatcagtttc atcaacacag tgacaataat
    12301 agctaaaagg tataaataaa cagaataaat aactaatgtg atccatttgc ttactaatat
    12361 ttctcctcga gaatactttc gataaaggag atttttcaat gtaccatatt gtgcttccat
    12421 cgaaatgatc gtgcttgcag ctgcaatcat gataaagaca atccaagatg tggcactaaa
    12481 aagctgagca gtcatttcaa ctggatcaat gatcgtcgtg tattttttgg ctagaagtgc
    12541 tgttcctatg agcaaaacaa ctaatagaac agataaaaca gcagttgact ttttcttgat
    12601 caatttaaat aattcttgtt ttacaagcaa tgtcattttt cttcttcccc ctttactgaa
    12661 tccagaattt ccaatagaga agattccaaa tcattcgtca gatgctggac gtctgtcaca
    12721 tggatatttt gtgcagacaa tagctggatc acggttccta ataattcttc gttttctttt
    12781 aaaagcttga ttttatcagg atcttccaaa gtatatccag cttctgtcaa gatcgttcga
    12841 gcagctagat catttgttgt agagataacg atgaaatctt gcgctgtttg gttcaattca
    12901 gccattgtac attgtttgat gatctttcct tgattgatca ggatcagctc atcgaccatt
    12961 ttttcaagct cgctgagtaa gtgactggag atcaagaaag aggtgccctg agtagccaag
    13021 tcggtaatga tttttcgcac atctcttgtt gcttgtggat ccaaaccgtt catcggctca
    13081 tctaaaataa cgatagacgg atggttcagt aaggcaagag caattcccaa tttttgtttc
    13141 attcccaacg agtaggattt cgcttttttg tgaatgtact tttccatctt gagctgattc
    13201 acgatagtgt cgatagcaga tacatcgttg gtttcagaga ataacttcag atgatcatag
    13261 cctgttaaga atggatagat acccgggtat tcgatcaatg ctcctacttg ttccaaccct
    13321 ttatgactag agggagaaat ctcattttca ccaatacaga ttgttccatc tgagtaatgg
    13381 atcagtccta aaatagcttt catgatcgtt gtttttccag cgccattagg acctactaat
    13441 ccaacgattt tgccagggga taagctaaaa ctgacatcgc tgagggcttg tttgtgacca
    13501 aagttcttgg ataattcttg gaccgaaaga cttttcaaaa atattcactc cttttctata
    13561 gatagtacaa gcatacacct gatgagtgga gaagtcgcta ggtcattgga cttatttctt
    13621 attttttcat aaaaaaattg aatattaaat aaaaaggctt attttttctg atcagtactt
    13681 attccaagtg tctagtggcc gctagtaatc ttgatgccaa tgatactgat gagtagcatc
    13741 cccacaaaga accaagtgga aagattcagc ttatcatgaa acaagaccac accaattatg
    13801 accgaaccaa ctgcgccaat ccctgtccag ataggataag agagactcat cggcaaactt
    13861 ttgattgcct ttgacaaaaa gtaaaaacta gcaatcatgc caatcactgt gtaaaaagaa
    13921 taattgattt tagaaaaacc atcactccat ttcatcatcg ttgaccagaa tacttccaaa
    13981 attcctgcta tgattaattc catccatgcc atacttacat tcctccttaa ctataaaaaa
    14041 atacacaaaa agaggaaaat catcccttca aagacctaat ggaatgatca tcctctttat
    14101 cctacccggt ggcagattgt atatcttttt ctgtagtata gcacacctat ccagatatcg
    14161 gcaatctcat actttttagt aaagtgtacc aagcactgac ggatatatcg ttagcggaaa
    14221 agaagatgaa tgctttgcaa tttcatagaa agaagttgtt atttattaat catttaaaaa
    14281 aaacagtaac tagaccttat ttctatatat tatcgggcaa taaattaaaa aaagctttac
    14341 cttacaataa gtaagataat ttttg
//
LOCUS       DAZKCW010000222        13339 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.064, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000222 DAZKCW010000000
VERSION     DAZKCW010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.064"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            68..253
                     /locus_tag="ACG84Z_002936"
     CDS             68..253
                     /locus_tag="ACG84Z_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFP9163688.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            411..578
                     /locus_tag="ACG84Z_002937"
     CDS             411..578
                     /locus_tag="ACG84Z_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163689.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            1196..1863
                     /gene="vanR-B"
                     /locus_tag="ACG84Z_002938"
                     /pseudo
     CDS             1196..1863
                     /gene="vanR-B"
                     /locus_tag="ACG84Z_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-B"
     gene            1866..3209
                     /gene="vanS-B"
                     /locus_tag="ACG84Z_002939"
     CDS             1866..3209
                     /gene="vanS-B"
                     /locus_tag="ACG84Z_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-B"
                     /protein_id="HFP9163690.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            3380..4186
                     /locus_tag="ACG84Z_002940"
     CDS             3380..4186
                     /locus_tag="ACG84Z_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HFP9163691.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            4204..5031
                     /gene="vanW-B"
                     /locus_tag="ACG84Z_002941"
     CDS             4204..5031
                     /gene="vanW-B"
                     /locus_tag="ACG84Z_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HFP9163692.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            5028..5999
                     /locus_tag="ACG84Z_002942"
     CDS             5028..5999
                     /locus_tag="ACG84Z_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HFP9163693.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            5992..7020
                     /gene="vanB"
                     /locus_tag="ACG84Z_002943"
     CDS             5992..7020
                     /gene="vanB"
                     /locus_tag="ACG84Z_002943"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HFP9163694.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            7026..7634
                     /locus_tag="ACG84Z_002944"
     CDS             7026..7634
                     /locus_tag="ACG84Z_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HFP9163695.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(7886..8890)
                     /locus_tag="ACG84Z_002945"
     CDS             complement(7886..8890)
                     /locus_tag="ACG84Z_002945"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFP9163696.1"
                     /translation="MQRGGKSRGKAAAAGSGKQKASNGERFLKKIERTGGEAVNRLTR
                     RRKVYEAIHTLRQEKGYEIASLCALSGIPRCSYYKWLHREESASEKENTLLLEEIIRL
                     YSEVKGIYGYRRMTLNVNSRLKRNYNHKRIYRLMKSVHMQAVIRRKKKHYVILEPRVT
                     AENVLNREFTANGPNEKWLTDVTEFKLINGKKAYLSAILDLHDKSIVAYALGQSNNNQ
                     LVFDTFDRAVRANPGAHPLFHSDRGYQYTNRQFKAKLDGIHATQSMSRPGRCIDNGPM
                     EGFWGILKSEMYYLRQFHTFEELKKAIDEYIDFYNTRRLQAKLKGLAPLAYRNQTLVA
                     "
     gene            complement(8773..9456)
                     /locus_tag="ACG84Z_002946"
     CDS             complement(8773..9456)
                     /locus_tag="ACG84Z_002946"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFP9163697.1"
                     /translation="MSLKGKIPPEVKIQAVEDYLAIRKGSTQIREELGIRLSTFQAWL
                     RKYQTEGPAGLHPKKHVTSYPSSLKLAAVEDYMGGGGSLDAMCRKYGISSHAVLQQWI
                     TLYNQGHREFKTRRAREETDMAEKEKLSQEQKLQAVLYCLEHQLDYRRTSEQYKITYQ
                     QIYSWVKKYQEQGEAGLLDRRGRRRPPSEYSEEEKAAAKLRQLEAENRRLQMENDFLK
                     KLNELEGRR"
     gene            9902..10333
                     /locus_tag="ACG84Z_002947"
     CDS             9902..10333
                     /locus_tag="ACG84Z_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFP9163698.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
     gene            10340..10573
                     /locus_tag="ACG84Z_002948"
     CDS             10340..10573
                     /locus_tag="ACG84Z_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFP9163699.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            10997..11197
                     /locus_tag="ACG84Z_002949"
     CDS             10997..11197
                     /locus_tag="ACG84Z_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFP9163700.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            11281..12474
                     /locus_tag="ACG84Z_002950"
     CDS             11281..12474
                     /locus_tag="ACG84Z_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9163701.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(12653..12931)
                     /locus_tag="ACG84Z_002951"
     CDS             complement(12653..12931)
                     /locus_tag="ACG84Z_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163702.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFF"
     gene            complement(13049..13309)
                     /locus_tag="ACG84Z_002952"
     CDS             complement(13049..13309)
                     /locus_tag="ACG84Z_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163703.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
BASE COUNT         3768 a         2890 c         3363 g         3318 t
ORIGIN      
        1 tatttcacat tttgtttctt ttattcttcg agcaaaagaa ttataatgta ccctgtggag
       61 gtgtactatg gactacatga cgttgaaaga ggcaggcgag aaatggggtg tgcccccacg
      121 atggataaac tactattgtg ctgcgggacg catccccggc gctgtaaaga tggcgacgat
      181 ctggctcatt cccaaaactg cggaaaagcc gattgacagg cgtacaaaga aaggaaaggc
      241 ggttactgaa tagtataatg aaaccggcgc attttggata tggttttgaa gagagagaaa
      301 gcatggtatt ttgtcacgga aaaactataa gatgatagat ggcaggctgc tccagaccga
      361 taaaaagtat tctcatctga aacagaaaga aaagatttac acatggatgt atgaagaagc
      421 gaaactttat catgacagaa atggaaaatg cccgaaacaa agacgaggaa gctgctgctg
      481 tatcagccgt atatggtaga attgaaaagg ccggcatctg gattctttat ggtgaagtct
      541 ccagacattg gataactgct ggtctaatgc gcctttgagt atggggtgat tgattttaat
      601 accggggagg tacggctttt tgaggaaaat attctgggat ttacatttgg cgattattac
      661 atttcctgta actgcaagga cacggatgat gaagatatga ggaatataga cttgctgatt
      721 ttctactgtc ttgaacggta ttaggactga atctgctgcg cggagtgcgg caagagcgac
      781 cggagggagt acacacaggc cctgcctgtg tgaaaagcca taccgcaagg tgcattcgca
      841 aaaaagaggc cgcgcatttt gctgaggctt ggggtgtccc caacaagcaa aacgagaacg
      901 ccgcaggcgg gcaagtggtg gatcagaata tccgtaaagg atattctgat ccattgcttg
      961 ccagtattat cgggatgttt tgacaaccgc tgtaatcgaa acatcccaaa cattaagaag
     1021 gtgttaatta ttattatctt gatttaattc gtttaaacca ataatataga tacatacacc
     1081 atgaaaagaa gcgagtatcc caatgacgga tgattaaaat ccgaaaagaa atcgctttga
     1141 aactacaggg aaactacaga ctgttatgtt atcttcttaa aatggaggga tttttatgtc
     1201 gatacgaatt ctacttgtcg aggatgatga tcatatctgt aatacagtaa gggcgtttct
     1261 ggctgaggca ggatatcagg tggatgcctg cacagatgga aatgaggcat acaccaagtt
     1321 ttacgaaaac acttatcaac tggttattct tgatattatg ctgcccggta tgaacgggca
     1381 tgaacttttg cgtgaatttc gtgcgaaaaa tgatactccc attctgatga tgacagccct
     1441 gtcggatgac gaaaaccaaa tccgggcgtt tgatgcagag gcagacgact atgtaacaaa
     1501 gccattcaag atgcagattt tactaaagcg ggtggaagcc ctgctgcggc gcagcggtgc
     1561 gctggcaaag gaaatccgtg tcggcaggct gacacttctg ccggaggatt tcacggtact
     1621 ttgtgacggt acagagctgc ccctgacacg aaaagaattt gaaatccttt tgctgctggt
     1681 gcagaacaaa ggcagaacct taacgcatga aatcattttg tcacgtatat ggggatatga
     1741 ctttgagggt gatggcagca cagtccacac tcccacactc atatcaaaaa tttgcgggcc
     1801 aagctgccgg aaaatatcat caaaaccatt cgcggtgtag gataccgatt ggaggaatca
     1861 taataatgga aagaaaaggg attttcatta aggttttttc ctatacgatc attgtcctgc
     1921 tactgcttgt cggtgtaaca gcaacactgt ttgcacagca atttgtgtct tatttcagag
     1981 tgatggaatt acagcaaaca gtaaaatcct atcagccatt ggtggaactg attcagaata
     2041 gcgataggct tgatattcaa gaggtggcag ggctgtttca ctacaataac caatcctttg
     2101 agttttatat tgaagataaa gagggaagcg tactctatgc cacaccaaat gccaatacat
     2161 caaatagttt tagacccgac tttctttatg tggtacatag agatgataat atttcgattg
     2221 ttgctcaaag caaggcaggt gtgggattgc tttatcaagg gctgacaatt cggggaattg
     2281 ttatgattgc gataatggtt gtattcagcc ttttatgcgc gtatatcttt gcgcggcaaa
     2341 tgacaacgcc gatcaaagcc ttagcggaca gtgcgaataa aatggcaaac ctgaaagatg
     2401 taccgccgcc gctggagcga aaggatgagc ttggcgcact ggctcatgat atgcattcca
     2461 tgtatgtcag gctgaaagaa accatcgcaa ggctggagga tgaaatcgca agggaacatg
     2521 agttggagga aacacagcga tatttctttg cggcagcttc tcatgagcta aaaacgccca
     2581 tcgcggctac aagcgttctg ttggagggaa tgcttgaaaa tatcggtgac tacaaagatc
     2641 attctaagta tctgcgcgaa tgcatcaaaa tgatggatag gcagggcaaa atcatttccg
     2701 aaatactgga gcttgtcagc ctgaatgatg ggagaatcgt acccatagct gaaccgttgg
     2761 acatagggcg cacggttgcc gagttgctgc ccgattttca aaccttggca gaggcaaaca
     2821 accagcggtt cgtcacagat attccagccg ggcaaattgt cctgtccgat ccgaggctgc
     2881 tccaaaaggc actatccaat gtcatattga atgcagttca gaacacgccg cagggaggcg
     2941 aggtacggat atggagtgag cctggtgctg aaaaatgccg cctttttgtt ttgaacatgg
     3001 gcgttcacat tgatgatact gcgcttccaa ggctgttcac cccattctat cgcattgatc
     3061 aggcgcgaag cagaaaaagt gggcgaagcg gtttaggact tgccatcgta caaaaaacgc
     3121 tggatgccat gagcctccag tatgcgctgg aaaacacctc ggatggcgtt ttgttctggc
     3181 tggatttacc gctcacatca acattgtaaa tatttaaaac ttaaatgatt ttgaccgaca
     3241 ggtataaccc tgccggtctt tttttgctgc tacaggaaaa ctacagactg gctacaggga
     3301 aagtacagat gcgcttgcca taataacaat cgtaccagcc acaaatcgta gttttattgc
     3361 aaaggaggca ttcgatcaaa tggaaaaaag caactatcat tccaatgcgg atcatcacaa
     3421 acggcatatg aaacaatccg tggaaaagcg ggcttttcta tgtgcgttca ttatttcgtt
     3481 cacagtctgc acgctgtttt tggggtggag actggcttcc gtattggagg caacacagat
     3541 accgcccatc cctgcaactc atacaggcag cagcactgac gtagtggaga atttggagga
     3601 aaacgctctt gccaccgcca aagaacaggg agatgaacag gaatggagcc tgattttagt
     3661 gaacaggcag aaccccatcc ccgcacagta cgatgtggag cttgagcaac tatcaaatgg
     3721 tgagcggata gatattcgga tttctcccta tcttcaagat ttgtttgatg ccgcaagaac
     3781 tgatggagtt tacccgattg tcgcatccgg ataccgaaca acagaaaaac agcaagaaat
     3841 tatggatgaa aaaattgccg aatataaggc gaaaggctac acctctgcac aggctaaagc
     3901 ggaagcagaa acttgggtgg ccgtgccggg aacgagcgag catcagcttg gtcttgctgt
     3961 ggatatcaat gcggacggaa ttcattcaac aggcaacgag gtttatagat ggctggatga
     4021 aaacagctat cgttttggtt ttattcgtcg ctacccacca gacaagacag agataaccgg
     4081 tgtgagcaac gagccgtggc attaccgata tgttggcatc gaagctgcca cagagatgta
     4141 caaccaaggg gtttgccttg aggaatattt aaaaccagaa aaatgagaaa aggatgttat
     4201 gttatggaca gaaaaagatt gacacagcgt ttcccgttcc tgcttccaat gagacgggcg
     4261 cagagaaaaa tgtgctttta tgcgggaatg agatttgacg gctgtcgcta tgcgcagacg
     4321 ataggggaaa aatcgctttc ccatttgctc tttgaaacgg attgcgcatt atacaaccac
     4381 aataccggat ttgacatgat ataccaggaa aacaaggtgt tcaacttaaa gctggcagca
     4441 aagaccttaa acggcttatt gataagaccg ggggaaacct tttctttctg gtggctggta
     4501 cgccatgcgg acaaagatac cccctataaa gacggcctta cggtgaccaa tggtaaactc
     4561 accaccatgt cgggcggcgg tatgtgccag atgagcaatt tactattttg gatgttcctg
     4621 catacgccat tgacaattat ccagcgcaga ggtcacgaag taaaggagtt tccagagcca
     4681 aacagtgacg agattaaagg ggtggatgca accatttcag agggctggat tgatttaaaa
     4741 gtgcgaaacg ataccgactg cacctaccaa atatgggtga ccttagatga tgagaaaatc
     4801 atcggtcagg tgtccgccga caaagagccc caagcattat acaaaattac aaatggcagt
     4861 atccagtatg tccgtgaaag tggcgggatt tatgaatatg cccaggttaa acggatgcaa
     4921 gttgccttag gtaccgggga aataatagat tgcaagctgc tttatacaaa caaatgcaaa
     4981 atctgttatc ccctcccgga aagtgtggat attcaggagg agaaccaatg agaaaaagtg
     5041 tgggcattac tgtttttgga tgcgaacagg atgaggcaaa tgctttccgc gctttatcgc
     5101 cggattttca tattatccct acgctgatta gcgatgcgat atcggcagac aacgcaaaat
     5161 tggccgctgg caatcaatgc gttagcgtag gccataagtc cgaggtttcc gaggcgacaa
     5221 ttcttgcgct gagaaaggtc ggggtaaaat acatttctac ccgcagcatc ggctgcgatc
     5281 acattgatac gactgccgcc gagagaatgg gaatctcggt tggcacggtt gcgtattcgc
     5341 cggacagcgt tgcggattat gctttgatgc tgatgctgat ggccatacgg ggtgcaaaac
     5401 ccaccatgca cgccgtggcg caacaagatt tcagattgga tcgtatccgg gggaaagaac
     5461 tgggggatat gactgtggga gttattggaa ccggccatat cgggcaagcg gtcgtcaaaa
     5521 ggctgcgggg atttggatgc catgtgctgg cctatgataa cagccgaaaa atggatgcag
     5581 attatgtcca gcttgatgag cttctaaaaa acagcgatat tgttacgctc catgtgccgc
     5641 tttgtgcgga tacccgccat ctgatcggtc agaagcaaat tggagagatg aagcaaggcg
     5701 catttttaat caacaccggg cgcggagcgc ttgtcgatac cggggcgctg gtggaggcgt
     5761 tggaaagcgg aaagctgggt ggtgcggcac tggatgtgtt ggagggcgag gatcagtttg
     5821 tttataccga ttgctcgcag aaagtgcttg accatccctt tttgtcgcag cttttaagga
     5881 tgccgaatgt gatcatcaca ccccatacgg cgtactacac tgagcgtgtg ctgcaggata
     5941 ctacagaaaa aacaatcagg aattgtctca attttgaaag gagtttacag catgaataga
     6001 ataaaagtcg caatcatctt cggcggttgc tcggaggaac atgatgtgtc ggtaaaatcc
     6061 gcaatagaaa ttgctgcgaa cattgatacg gaaaaattcg atccgcacta catcggaatt
     6121 acaaaaaacg gtgtatggaa gctatgcaag aagccatgta cggaatggga agccgacagt
     6181 ctccccgcca tactctcccc ggataggaaa acgcatgggc tgcttgtcat gaaagaaagc
     6241 gaatacgaaa cacggcgtat tgatgtggct ttcccggttt tgcatggcaa atgcggggag
     6301 gatggtgcga tacaggggct gtttgtattg tctggtatcc cctatgtggg ctgtgatatt
     6361 caaagctccg cagcttgcat ggacaaatca ctggcctaca ttcttacaaa aaatgcgggc
     6421 atcgccgttc ccgaatttca aatgattgat aaaggtgaca agccggaggc gggtgcgctt
     6481 acctaccctg tctttgtgaa gccggcacgg tcaggttcgt cctttggcgt aaccaaagta
     6541 aacggtacgg aagaacttaa cgctgcgata gaagcggcag gacaatatga tggaaaaatc
     6601 ttaattgagc aagcgatttc gggctgtgag gtcgggtgtg cggtcatggg gaacgaggat
     6661 gatttgattg tcggcgaagt ggatcaaatc cggctgagcc acggtatctt ccgcatccat
     6721 caggaaaacg agccggaaaa aggctcagaa aatgcgatga ttacagttcc cgcagacatt
     6781 ccggtcgagg aacgaaatcg ggtgcaggaa acggcaaaga aagtatatcg ggtgcttgga
     6841 tgcagagggc ttgcccgtgt tgatcttttt ttgcaggagg atggcggcat cgttctaaat
     6901 gaggtcaata ccctgcccgg ttttacatcg tacagccgct acccacgtat gatggccgcc
     6961 gcaggaatca cgcttcctgc actgattgac agcctgatta cattggcgtt aaagaggtga
     7021 taagtatgga aaatggtttt ttgtttttag atgaaatgtt gcatggcgtc cgttgggatg
     7081 ccaagtacgc cacatgggat aacttcacag gaaaaccggt ggatgggtat gaggtgaatc
     7141 gcatcatcgg cacaaaggcc gtggcgtttg ctctgcgcga ggcacaaatc catgcggctg
     7201 cgcttggcta tggcttgctt ttatgggatg gatatcggcc aagaactgcg gtggactgct
     7261 tcctgcgttg ggcagcgcaa ccggaggaca atctcacaaa agaaaaattt taccccaata
     7321 tagagcgagc cgagttgatt acaaagggtt atgtggcctc acaatccagc catagccgtg
     7381 gaagcgcaat tgatcttacg ctctaccacc tggatacagg ggaacttgtt tcaatgggaa
     7441 gtaacttcga ttttatggac gaacggtcgc atcatacagc aaaagggata ggggatgcag
     7501 aggcacaaaa tcgaagatgc ttgcgtaaaa tcatggaaag cagcggattt cagtcttatc
     7561 gctttgaatg gtggcactat aagttgattg atgagccata ccccgatacc tattttaatt
     7621 ttgccgtttc ataatgaaag tattggtttt gtatcagatt ttggatttga taaaatctat
     7681 gctggtcatg gacaatcttt tactggaaag tggttaaagc atcttttgta atacattgca
     7741 aattatagta ttcaatctgc ccagcggcag aaaagaaaaa aaccgctgtt gggcagacct
     7801 ttcccacgcc cattttgtat tttgctggcg gcggttttga gaaatgaacc gccccctgtc
     7861 aagtagacag atgaaaaaag aaaaattacg ccacgagggt ctggttcctg taagcaaggg
     7921 gagccaggcc ctttaactta gcttgaagcc gccttgtatt gtaaaagtct atgtattcgt
     7981 cgatggcttt cttcaattcc tcgaaggtat gaaattgccg gaggtagtac atttcagatt
     8041 tgagaatccc ccagaagccc tccatagggc cgttgtcgat gcagcggccg ggccgggaca
     8101 tactctgcgt tgcatggata ccgtccagct ttgctttgaa ctgccggttg gtgtactgat
     8161 agcccctgtc gctgtgaaac agaggatggg cgccggggtt ggctctcacc gctctgtcaa
     8221 aggtgtcaaa aacaagctga ttgttgttgg attggcccag tgcatacgca acgatgcttt
     8281 tgtcatggag atcaaggatc gcactcaggt atgctttctt cccattgata agtttgaatt
     8341 ctgtgacatc tgtcagccat ttctcattgg gaccatttgc cgtaaattct ctgttcaata
     8401 cgttttccgc ggtaacacgc ggttctaata tgacatagtg ctttttcttt cggcgtatca
     8461 cggcctgcat atgtacactt ttcatcaggc ggtaaatccg cttgtggttg tagtttcttt
     8521 tgagccggct gttcacattc agcgtcatac ggcgataacc gtagatgcct tttacttcgc
     8581 tgtacaaacg gatgatttct tccagcaaga gggtattttc tttttctgag gcactttctt
     8641 cccggtgaag ccatttgtag taagaacagc ggggaatccc ggataacgcg cataacgatg
     8701 cgatttcata tcctttttcc tgacgaagcg tatggatcgc ctcatagacc ttcctgcggc
     8761 gtgtgagcct gtttaccgcc tcccctccag ttcgttcaat ttttttaaga aatcgttctc
     8821 catttgaagc cttctgtttt ccgcttccag ctgccgcagc tttgccgcgg ctttttcctc
     8881 ctcgctgtat tcggaaggag ggcggcgtct cccccggcgg tcaagcaacc cagcttctcc
     8941 ctgctcctga tattttttga cccagctata gatctgctga taggtgatct tgtactgttc
     9001 gctggtccgc cggtagtcca gttgatgttc taagcagtat agtactgcct gcagcttttg
     9061 ctcctgcgat aatttttctt tctcggccat atctgtttcc tcccgcgctc tgcgtgtctt
     9121 gaactctcta tggccttgat tatacaacgt aatccattgt tgtaaaaccg catgggagga
     9181 aatcccgtat ttgcggcaca tggcatccag cgagcctcct ccgcccatgt agtcttctac
     9241 tgccgccagc ttcagtgagg atggataact tgtaacatgc tttttcggat gcagacccgc
     9301 aggcccctcc gtctgatatt tccgcagcca tgcctggaaa gtgctcaatc gtatgcctaa
     9361 ctcttcccgg atctgtgtgg aacccttacg gatcgctagg tagtcctcca cagcctgaat
     9421 ctttacctcc ggcggtattt tgccttttaa actcatgata attgctccct ccgtttcgac
     9481 agtttaattt ttttgctgtc tacttcagag ggagcatatc aaaatcaagg ccgccgttct
     9541 tttctggcag caaaaggtgt ggcggcccat aggaggatgc cgctatgctg ttttgctatt
     9601 gccatgctct aatccacttc caccactcaa aaaaagcctt gcccctccac agggctattc
     9661 cggttatgag tatgtactat accatgtaaa tcagcagcat agcaaagcat tttctcgccc
     9721 ggtaggtttg cgacctgccg ggcgattttt gtcgtctttt gcggcccggc tgtccccaaa
     9781 aaaatttttt gagaaatttt caaaaaggag gtatttagcg ggtagctggc ggccttgtca
     9841 aagtcttgtt agcggaaagg gagagaacca cctaagtccc ccacagaaag ggggtgagaa
     9901 gatggatgct atcccccgcg actatgaagc gcggtgcatg ttcgatgctt tttgcaagac
     9961 ggtactgcgt aacgaggcca aaagctactt ggctgaaatg aagcgccgcc gtgaccgtga
    10021 agtgtcacta agctctttgt cacaggcaga tttggacaag ctctgtacag tagatcacta
    10081 ccccagcgac agctttacgt tttcgtcgca tggctatgac ctacatatca acaatgagct
    10141 tgttgccgaa gcctttgccg cgctgcccag catggagcag agtattttaa tcctgcactg
    10201 tgttctggat atggcagatg gtgagatcgg cggccttgtg ggaatgtccc ggagtgccgt
    10261 tcagcggcac aggacaaata ccttatcgga gctgcggaaa cagctaaagg cgttgatgcc
    10321 gaagggaggt tagacgcgga tgaagaaccc gaactacaag ggcattgagc ttttgcccct
    10381 ttcggtgatc gaggccgccc gcgctgggga tgccggagcc gtagagcgcg ttttgcagta
    10441 ttacagcggt tacatgaaca agctgtgtac ccggacgctc tatgacgaaa acggctatcc
    10501 gcatgtgtgt ctggacgagg ccatgaagcg ccgtctggaa atcaagctca tccacgctat
    10561 cgtcacgaac tgacgaaccg gccccggcag catgaaacgg cttacccttt ccccgtttcg
    10621 gtgttttccc ggtggcctga tcgcaccttg ataaatatgc ccgcaagata acggcggcgc
    10681 atcatagggc atacggacac attctgtctg tgccgagccg gacggctggt gcgccatgat
    10741 acttttccct acgggaaaag cggagcgagg aacaccacgc cgcaatgtga gcgtggcggc
    10801 ttgcgggcga cgacgtacag gcaggactat gatactccct tatagccaca gtccgagcgt
    10861 taaaagcgtc gcaggcaatg ggtagggccg cgtgagaacc acgcgggggt gaaagtcccg
    10921 tggagctgtg ccagcagccg tccgtctatg cccctaaatc acacaaacct ttgaatttgt
    10981 gaaagggggc tgcattatga accatgatgt gcctatttgg gaaaaataca cgctgacgat
    11041 tgaggaagcg tctaaatatt tccgtatcgg agaaaacaaa ttgcgtaagc tggccgagga
    11101 aaatccggcc tctggctggg tcattatgaa tggcaaccgc atccagatca aacgcaagca
    11161 gtttgagaaa ataattgaca ctttggacac aatctaatag tgaaaaaggg ccgcagatat
    11221 gttataataa tttataagca tatatgcggc tctttccgtc atggaaagga gcatgacgag
    11281 atgtcagaaa aaagacgaga cagcaaaaat cgcgttttgc ggtctggaga gagccagaga
    11341 aaagacggac gatatgctta caaatatgtt gatacctttg gaaaaccgca gtttgtttac
    11401 tcatggaagt tagtgcctac ggataagacc ccggcaggta aacgggagga tatttcactc
    11461 cgggaaaagg agaaagaaat ccagaaagac cttgacgacg ggatagacac catcggcaag
    11521 aaaatgaccg tctgccagct ctacgccaag cagatcaggc accggggcaa tgtgaagcac
    11581 aacaccaaac tgggccggga acggctgatg cgtattctgg aacaagatcg gctggggagc
    11641 tgcccgattg acagtgtgaa gctgtccgac gcaaaggaat gggcgcttcg gatgaaagaa
    11701 aagggccttt cttataagac catcaataac gacaagcgtt ccctgaaagc ggctttttac
    11761 accgccatac aggacgattg catccgaaaa aacccgtttg acttccagct tagtgacgtt
    11821 ctggacgacg atacggaacc aaaggtgcct cttacaccag cacaggaaga aagttttctg
    11881 tcctttattc aaggtgataa ggtttaccaa aagcattatg acgcaatcgt tattctgctg
    11941 gggacagggc ttcgcatttc ggaactgtgc ggactgacgg acaaagattt ggattttgaa
    12001 aaccgggtaa tcatcgtgag ccaccagctt ttgagaaata ccggcgtcgg ttactatatt
    12061 gacgaaccca agacccaaag cggcgtcaga aaaatcccca tgaatgagga agtgtatcag
    12121 gcgttccagc gagtgataaa aaaccgcaaa ggtgcaaagc cgttcattat tgacgggtat
    12181 gccaatttcc tgtttctcaa acagaacggc tatcccatga cggcggtaga ttatggcggg
    12241 atgtttggca ggcttgtgaa gaagtacaac aagagccatg aagaagcgtt gccgaaaacg
    12301 acgacgcccc atgctatgcg tcatacattc tgcacccggt tagccaatgc gggaatgaac
    12361 cccaaagcct tgcagtacat tatgggacat tccaatatca ccatgacgct gaactattat
    12421 gcacacgcca cattcgattc cgcaagggca gaaatggaac ggctggcagc ctgacacaag
    12481 gccggtttta ctactccatt tactactttt gagggggaaa tggtgagagg taataagaac
    12541 atttgtaagt atctaacaat atcaaaaatg ccggaaaagc ccggaaacac gggctatacc
    12601 gacattcaag aacttctaaa aagataatct aaaatcccat ataattttcc tcctaaaaaa
    12661 atagcacaat ggcaaagatc gtaagagaga tcataagccc caatgaatga ctaaaaagaa
    12721 aagcagaatc acatgccata tcatcccata tttcttcaag aaaataaata agcgggaaaa
    12781 agggaaggaa tagtagaaca tcgatccagc accatttttt tcttcttttg aaataacata
    12841 aaacaataaa catgaacgtg cagggaagta aaaacaaagc tttactcata actaacaaaa
    12901 taccagctcc ttttattttt ttctccccca cattcaaaga gtaacaatgg tatgtactta
    12961 ataatagaaa aatggatcaa cttgtatgaa taacagctga aaagatctgc accaaataaa
    13021 aaacttccag ccaaaactga ctggaagttt atttttttct gaaatattct aacacaaata
    13081 tgaaaaagat ggccgaagct aataagccga tttcgtagca aaacaatgag ataccagagt
    13141 cgtaataata aaatcctcta atcttatgga taaaatagat catcggacaa gcagataaga
    13201 gtaagtattt gttaggcctt ttgaataagt aaaagaaagc actggtcatt atgataaatg
    13261 gtatccaaaa caaaagttta cttaagacaa tcaaatgatc aactcccata ttttttacca
    13321 agagagatca taacatctt
//
LOCUS       DAZKCW010000223        10363 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.076, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000223 DAZKCW010000000
VERSION     DAZKCW010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.076"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            293..658
                     /locus_tag="ACG84Z_002953"
     CDS             293..658
                     /locus_tag="ACG84Z_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFP9163704.1"
                     /translation="MTAEVCTTTCIHKEKVASVKNNLKDKDLSTLLVLGKCFSDSSRI
                     KIFYALETYKEMCVCDLAAILNASIATTSHHLRFLKKNGMAKSRQYGKVVYYSLANED
                     ILSAIHVFLKLSENLSMKS"
     gene            675..1288
                     /locus_tag="ACG84Z_002954"
                     /pseudo
     CDS             675..1288
                     /locus_tag="ACG84Z_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010620830.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
     gene            complement(1400..1720)
                     /locus_tag="ACG84Z_002955"
     CDS             complement(1400..1720)
                     /locus_tag="ACG84Z_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFP9163705.1"
                     /translation="MNSLSTSPLKNESIQEVSKIFKMISDPTRLSILFLLQKEELSVG
                     AIAHSLSMEQSAISHQLKTLKTSRLVKSKRAGKNMIYSLDDLHIFSILEQVSTHIEEQ
                     EKEK"
     gene            1976..3883
                     /locus_tag="ACG84Z_002956"
     CDS             1976..3883
                     /locus_tag="ACG84Z_002956"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFP9163706.1"
                     /translation="MKEIQEQHSHENNSHDHGKMPIILYFIGLALSLIALFVNGENNL
                     IQNTLFSIASISAGYHVIILEGIGETIENSKRQHKFTPNSHILMGIAAIGASLIGNFW
                     EGTLLVLIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLIMQDGNTTIVNVSELKVG
                     DQLQVLNGDQVPIDGVIVSGSTSIDESSINGESIPKEKSKGDGVFGSTINGTGTFTME
                     VTKETNDTVFSKILQLVNQNQENQTKASSIIQKFEPKYVKFVLIAIPLFILLAPMLFD
                     LTWSQSIYRGLVLLVAASPCALAAATVSVTLSATSNLAKRGVLSKGSAYLSQLADIQA
                     IAFDKTGTLTKGKPEVTNYYFSDSVNEENMIDIVVALEKESNHPLASAILDKFEPKNK
                     LAIEVENQIGKGLIGDYNENTYRIGKPTSFEAVSDDYTRLNKEWASEGNTVVYVSENE
                     KVIGLIALMDIPSEHAKATIDYFKKCGIHTTLITGDSEMTGQAVGKQLGVDQVIANVM
                     PEDKSNIINEQKETYGITAMVGDGINDAPALVKADVGIAMGEGTDVAVDVSDLVLMKN
                     DLSKLVKAHEISLKMNRVIWQNIIFSMVVVAFLITVSLVGLTDIAISVIVHEGSTLVV
                     ILNGLRLLKSK"
     gene            3977..4198
                     /gene="relB"
                     /locus_tag="ACG84Z_002957"
     CDS             3977..4198
                     /gene="relB"
                     /locus_tag="ACG84Z_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFP9163707.1"
                     /translation="MTVISLRIDTQEDKLIKEYAKAKNISVSALIRSSVLEKIEDEID
                     LGLYNQAMKDHKENPKSISFEDMLKELSD"
     gene            4199..4471
                     /locus_tag="ACG84Z_002958"
     CDS             4199..4471
                     /locus_tag="ACG84Z_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFP9163708.1"
                     /translation="MSSGYQVEFEKGAQKALKKMDKYQSLLIMGWIQKNLVNCTDPRQ
                     HGKGLTVNRSGEWRYRIGDYRLIADINDETVTILMLEIGHRKNIYK"
     gene            complement(4602..7568)
                     /locus_tag="ACG84Z_002959"
     CDS             complement(4602..7568)
                     /locus_tag="ACG84Z_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFP9163709.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            7714..8289
                     /locus_tag="ACG84Z_002960"
     CDS             7714..8289
                     /locus_tag="ACG84Z_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFP9163710.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            8503..9198
                     /gene="vanR-A"
                     /locus_tag="ACG84Z_002961"
     CDS             8503..9198
                     /gene="vanR-A"
                     /locus_tag="ACG84Z_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFP9163711.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            9176..10345
                     /gene="vanS"
                     /locus_tag="ACG84Z_002962"
     CDS             9176..10345
                     /gene="vanS"
                     /locus_tag="ACG84Z_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFP9163712.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRGSVAKF"
BASE COUNT         3347 a         1735 c         1952 g         3329 t
ORIGIN      
        1 gatttttaaa tctgggattt tccgcttttt tgagttcttg aaaaaaaata agagtataga
       61 gtatgttctt tataaaatta attttcgtgt aaattattaa aaatttaata ataaaattta
      121 aattcctatt aagttgtaac acatgaaatt gcttaaaata gtgtatcaaa aaccttgttt
      181 tattaatgtt gaatttattt gaaaggtcta cagattaaca tattattgac aaaacaatat
      241 ttaaatagtt atacttcatt caaacgtctg tttgaacgag gtggtgaagt taatgactgc
      301 agaagtatgt acaactactt gtatacataa agaaaaagta gctagtgtta aaaataattt
      361 aaaagataaa gacctttcaa ctttacttgt attaggaaaa tgttttagcg attcttctag
      421 gattaaaatt ttctatgctt tagaaacgta taaggagatg tgcgtttgtg atttagcagc
      481 gatacttaat gctagtattg ctacaacgtc acaccattta cgttttttga aaaagaacgg
      541 aatggcgaaa tcacgtcaat atggaaaggt agtttattac tctttagcga atgaagacat
      601 cctttccgct attcatgttt ttttaaagtt atcagaaaat ctatctatga aatcttagtt
      661 tggaggaagt tattttgtta caaagtattt tttcagctat cgctgtttat atttctacca
      721 gcattgatta tttgtttatc ttgctgatta ttttttctca aagtcataca aaaaagggct
      781 ccgtcagatt ttttggggtc aatatctagg aacaggtatc ttagtagccg taagtttatt
      841 tgcagcatat gtgctgaatt tcattccgca agattggatc attgggcttc tcggtctaat
      901 tccgattttc ttaggaatca gagtggcatt ggttggcgaa gaggaggaag aagaagagga
      961 agtcgttgaa aagcttgaat caagaggaac aaaccgcttc ttttggaccg ttgccttaat
     1021 aacaattgct tctggtggcg ataacttagg gatttatatt ccttactttg cctcgttatc
     1081 tttttcagag attgtcaccg ctctaatcgt atttgctatt tctgttgcgg ttctttgcta
     1141 tatcagttac aaattagcca agatttcttt tgtttccgaa accttagaaa aatatgaacg
     1201 aatccttgtt cctatagtgt ttattggctt aggaatttat attttgatag aaaatgggac
     1261 gattcaaaca ctattaaatt ttatataaac aactacgata gtgaagttca aataaaaaaa
     1321 gacagcgaga ttttaactcg ctgtcttttt ttatttgaac taatgaattg taaaatcatt
     1381 ttaaccttgt agtttgtctt tatttttctt tttcttgttc ttcgatatga gttgaaactt
     1441 gctcaagaat actaaaaata tgaagatcgt caaggctata aatcatattt ttaccagctc
     1501 tttttgattt tactaatctt gaagtcttta aagtttttaa ctggtgagaa attgctgatt
     1561 gttccatact caaagaatgc gcaatagctc caacgctaag ttcttctttc tgcagaagaa
     1621 ataaaattga aagtcgggta gggtcactga tcattttaaa tattttactt acctcttgga
     1681 tagattcatt ttttaatgga gaagttgata atgaattcat aagaatttct ctccttcata
     1741 tgtttgttta ttcacattta gattatcata atatttttat aaagcaagat tttttgtata
     1801 agggtagcta ttttagagtc ctattttttt tatcacctaa ataagataac tatttttttg
     1861 acaaattaga tagagcgata taaaatgaat gtatagacat atgaatgttc gttcaaacgt
     1921 aattcgtaag cattacgatt tctaaaaaaa agttttatta agaaaggtga tagaaatgaa
     1981 agagattcaa gagcaacact cacacgaaaa taatagtcac gatcatggga aaatgccaat
     2041 tattttgtac tttattggtt tagcattgtc gctcattgcg ttatttgtaa acggagaaaa
     2101 taatttaatc caaaacactt tgttttcaat tgcttcaatt agtgctggtt atcatgtcat
     2161 tattcttgaa ggaattggag aaacgattga aaactcaaaa agacaacaca aatttacccc
     2221 taattctcat attttaatgg gaatagctgc aataggtgct tctctgatag gaaatttttg
     2281 ggaaggaacg ttattggttc ttattttctc tggagcacat tttcttgaag attatgctga
     2341 aggaagaagt aaaagagaaa ttaccaagtt attagaaatg aatccaacaa cagctaggct
     2401 aatcatgcaa gatggcaata caacaatcgt taatgttagt gagttgaaag taggagatca
     2461 acttcaagtg ttaaacggtg accaagtacc gattgacgga gtaatagtat caggctctac
     2521 ttcgattgac gaatcttcta ttaatggtga gagtatacct aaagagaaat caaagggaga
     2581 cggagttttt gggagtacaa ttaatggaac gggtaccttt actatggaag tcacaaaaga
     2641 aactaacgat actgtctttt caaagatttt acaactagtg aatcaaaatc aagagaatca
     2701 aacaaaagcg tctagtatta tccaaaagtt tgagcctaag tatgttaaat ttgttttaat
     2761 tgcaatccca ctcttcattt tacttgctcc tatgctgttt gatttgacat ggtcacaaag
     2821 tatttataga ggattagtcc ttttagtcgc agcttctccg tgtgctttag cagcagctac
     2881 cgtatccgta acattgtcag ccacttctaa tctagcaaaa agaggcgtac tttcaaaagg
     2941 aagtgcctat ttgtcccaat tagcggatat tcaagccatt gcctttgata aaacaggaac
     3001 attaactaaa gggaaaccgg aagtaaccaa ttattacttt tctgattctg tgaacgagga
     3061 aaatatgatt gatatcgtag tggctcttga aaaagaatca aatcacccgt tagcaagtgc
     3121 tattttagac aagtttgaac caaaaaataa actagctatt gaagtggaaa atcagattgg
     3181 aaaaggttta ataggcgatt ataacgaaaa cacttatcgt ataggtaaac caacttcttt
     3241 tgaggctgta tcggatgact atacacgttt gaataaagaa tgggcttcag aaggtaatac
     3301 ggttgtatat gtatcagaaa atgaaaaagt aatcggcctg atagcattaa tggatattcc
     3361 aagtgaacat gcgaaagcaa ctatagatta ctttaagaag tgtggtatcc ataccacttt
     3421 aattactggg gattctgaaa tgacagggca agctgttggt aaacaattag gagtagatca
     3481 agtaattgca aacgtcatgc cagaagataa atctaacatt atcaatgaac aaaaagaaac
     3541 ctatggtata accgctatgg tgggagatgg tataaacgac gcacctgctc ttgtgaaggc
     3601 agatgttgga attgctatgg gagagggtac ggatgttgca gtagatgtat ctgatctagt
     3661 attaatgaaa aatgatttgt ctaaattggt aaaagctcat gaaatttctt taaaaatgaa
     3721 tcgagttatt tggcaaaata ttattttctc aatggtagtt gtcgcttttc taattaccgt
     3781 aagcttagta ggattaacgg atatagccat tagtgtgatt gttcatgaag gaagtacctt
     3841 agtcgtgata ttaaatggtc ttcgattatt aaagtctaaa taaatacatg aaattggata
     3901 aaatcatgta tctaaagttt gcagcctctc taattttgta ttacaatgta tatacaaaaa
     3961 gaagggggtg attctaatga ctgtcatatc gctcagaatt gatactcagg aagataaatt
     4021 aattaaagaa tatgctaagg cgaagaatat ttcggtttcg gctctgatta gaagttctgt
     4081 cttggaaaaa atcgaggatg aaattgattt gggcctatat aatcaagcca tgaaggatca
     4141 taaagagaat ccgaaaagta tttcttttga agacatgcta aaggagctat ctgattaaat
     4201 gagctcaggt tatcaagtcg agtttgaaaa aggagctcaa aaagcgttaa aaaaaatgga
     4261 caaataccaa tcccttttaa ttatgggatg gattcaaaag aatctagtga attgtaccga
     4321 tcctaggcag catggaaaag gattaaccgt caatcgatca ggcgaatggc gctatagaat
     4381 cggtgattat cgcttaatag ctgatatcaa tgacgagacc gtaaccattt taatgttaga
     4441 gattggtcat agaaaaaata tttacaaata aaccattcaa attgagtgca agcatgttta
     4501 ataaaaaagg attctactgc tttttaaggg gtagcgtcag gaaaatgcgg atttacaacg
     4561 ctaagcctat tttcctgacg aatccctcgt ttttaacaac gttaagaaag ttttagtggt
     4621 cttaaagaat ttaatgagac tactttctct gagttaaaat ggtattctcc tagtaaatta
     4681 atatgttccc aacctaaggg cgacatatgg tgtaacaaat cttcattaaa gctacctgtc
     4741 cgttttttat attcaactgc tgttgttagg tggagagtat tccaaatact tatagcattg
     4801 ataattatgt ttaaagcact ggctctttgc aattgatgct gtatggtgcg ttctctaagc
     4861 tcaccttgtt ttccgaagaa aatagctctt gccaatccat tcatggcttc tcctttattc
     4921 aatcctcttt gtatttttct tcttaatgat tcatccgata tataattcaa aataaagatc
     4981 gttttttcta ttcggcccat ctcacgtaag gctgtagcta agctgttttg tcttgaatag
     5041 gaacctagct tccccataat aagggatgct gaaactgttc cctcccttat agaatgagct
     5101 aatcgcaaaa catcctcata attttcttta atgacctttg tatttatttg tccacgtaaa
     5161 atggcttcta gttttggata ctcacttgct ttatctatcg taaataattt tgagtccgat
     5221 aaatccctta ttcttggggc aaatttaaat cctaataaat gagtcagtcc gaatatttgg
     5281 tcagtgtaac cggcagtgtc tgtataatgt tcctctatgt ttagatccgt ctcatgatgt
     5341 aacaaaccat ccaaaacatg aatcgcatct cttgaattag tatgaataat ctttgtgtag
     5401 taagaagaga attgatcact tgtaaatcgg tagatggtgg ctccttttcc agttccataa
     5461 tgtggatttg catctgcatg tagtgatgaa acacctagct gcattctcat accatctgac
     5521 gaagatgttg taccgtcgcc ccaatagaaa ggcaattgta atttatgatg aaagtttact
     5581 aatatggctt gggctttatt catggcatct tcatacatgc gccattgaga tacattggct
     5641 agttgcttat atgtaagtcc gggtgtggct tcggccatct tgctcaagcc aatattcatt
     5701 cccattccta aaagggcagc catgataatg attgtttctt ccttatctgg ttttcgatta
     5761 ttggaagcat gagtgaattg ctcatgaaat cctgttatat gggccacatc catgagtaaa
     5821 tcagttaatt ttattcttgg tagcatctga taaaggcttg cactaaattt ttttgcttct
     5881 tctggaacat ctttttctaa gcgtgcaagt gatagctttc ctttttcaag agaaacccca
     5941 tctaacttat tggaattggc agctaaccac tttaaccttt cattaaagct gctggttctc
     6001 tccgttatat aatcttcgaa tgataaacta actgataatc tcgtattccc cttcgattga
     6061 ttccatgtat cttccgaaaa caaatattcc tcaaaatccc tatattgtct gctgccaaca
     6121 atggaaacat ctcctgcccg aacatgctcc cgaagttctg ttaaaacagc catttcatag
     6181 taatgacgat taattgttgt accatcatcc tcgtataaat gtcttttcca tcgttttgaa
     6241 ataaaatcca caggtgagtc atcaggcact tttcgctttc cagattcgtt cattcctcgg
     6301 ataatctcaa cagcttgtaa aagtggctca tttgcctttg tagaatgaaa ttccaatact
     6361 cttaatagcg ttggcgtata ttttcttagt gaataaaacc gtttttgcag taagtctaaa
     6421 taatcatagt cggcaggacg tgcaagttcc tgagcctctt ctactgaaga gacaaaggta
     6481 ttccattcaa taaccgattc taaaacctta aaaacgtcta atttttcctc tcttgcttta
     6541 attaatgctt gtccgatgtt cgtaaagtgt ataactttct catttagctt tttaccgttt
     6601 tgtttctgga tttcctcttg agccttacga ccttttgata acaaactaag tatttgccta
     6661 tcatgaattt caaacgcttt atccgttagc tcctgagtaa gttgtaataa atagatggtt
     6721 aatatcgaat aacgtttatt ttcttgaaag tcacggaatg catacggctc gtatcttgag
     6781 cctaagcgag acagctgcaa caggcggtta cggtgcaaat gactaatttg cactgtttct
     6841 aaatccattc ctcgtatgta ttcgagtcgt tctattattt ttagaaaagt ttcgggtgaa
     6901 ggatgacccg gtggctcttt taaccaaccc aatatcgttt tattggattc ggatggatgc
     6961 tgcgaggtaa taatcccttc aagcttttct ttttgctcat ttgttagaga tttactaacc
     7021 gtattaaata gcttcttttc agccattgcc cttgcttccc acaccattct ttcaagtgta
     7081 gtgatagcag gcagtataat tttgtttttt cttagaaaat ctatgcattc atgcagtaga
     7141 tgaatggcat caccattttc caaagctaat tgatgaaggt acttaaatgt cattcgatat
     7201 tcactcaggg taaaagttac aaagtcgtat tcacttcgaa tttctttcaa atgatcccaa
     7261 agtgtatttt ccctttgagg ataatgatca agcgaggatg gactaacacc aatctgtttc
     7321 gatatatatt gtatgaccga atctgggatg cttttgatat gagtgtatgg ccaaccggga
     7381 taccgaagaa cagctaattg aacagcaaat cctaaacggt tttcttccct ccttcgctta
     7441 ttaactattt ctaaatcccg tttggaaaaa gtgaagtagg tccccagtat ccattcatct
     7501 tcagggattt gcataaaagc ctgtctctgt tccggtgtaa gcaattctct acctctcgca
     7561 attttcattc agtatcattc catttctgta ttttcaattt attagttcaa ttatatatca
     7621 atagagtgta ctctattgat acaaatgtag tagactgata aaatcatagt taagagcgtc
     7681 tcataagact tgtctcaaaa atgaggtgat attttgcgga aaatcggtta tattcgtgtc
     7741 agttcgacta accagaatcc ttcaagacaa tttcagcagt tgaacgagat cggaatggat
     7801 attatatatg aagagaaagt ttcaggagca acaaaggatc gcgagcaact tcaaaaagtg
     7861 ttagacgatt tacaggaaga tgacatcatt tatgttacag acttaactcg aatcactcgt
     7921 agtacacaag atctatttga attaatcgat aacatacgag ataaaaaggc aagtttaaaa
     7981 tcactaaaag atacatggct tgatttatca gaagataatc catacagcca attcttaatt
     8041 actgtaatgg ctggtgttaa ccaattagag cgagatctta ttcggatgag acaacgtgaa
     8101 gggattgaat tggctaagaa agaaggaaag tttaaaggtc gattaaagaa gtatcataaa
     8161 aatcacgcag gaatgaatta tgcggtaaag ctatataaag aaggaaatat gactgtaaat
     8221 caaatttgtg aaattactaa tgtatctagg gcttcattat acaggaaatt atcagaagtg
     8281 aataattagc cattctgtat tccgctaatg ggcaatattt ttaaagaaga aaaggaaact
     8341 ataaaatatt aacagcctcc tagcgatgcc gaaaagccct ttgataaaaa aagaatcatc
     8401 atcttaagaa attcttagtc atttattatg taaatgctta taaattcggc cctataatct
     8461 gataaattat taagggcaaa cttatgtgaa agggtgataa ctatgagcga taaaatactt
     8521 attgtggatg atgaacatga aattgccgat ttggttgaat tatacttaaa aaacgagaat
     8581 tatacggttt tcaaatacta taccgccaaa gaagcattgg aatgtataga caagtctgag
     8641 attgaccttg ccatattgga catcatgctt cccggcacaa gcggccttac tatctgtcaa
     8701 aaaataaggg acaagcacac ctatccgatt atcatgctga ccgggaaaga tacagaggta
     8761 gataaaatta cagggttaac aatcggcgcg gatgattata taacgaagcc ctttcgccca
     8821 ctggagttaa ttgctcgggt aaaggcccag ttgcgccgat acaaaaaatt cagtggagta
     8881 aaggagcaga acgaaaatgt tatcgtccac tccggccttg tcattaatgt taacacccat
     8941 gagtgttatc tgaacgagaa gcagttatcc cttactccca ccgagttttc aatactgcga
     9001 atcctctgtg aaaacaaggg gaatgtggtt agctccgagc tgctatttca tgagatatgg
     9061 ggcgacgaat atttcagcaa gagcaacaac accatcaccg tgcatatccg gcatttgcgc
     9121 gaaaaaatga acgacaccat tgataatccg aaatatataa aaacggtatg gggggttggt
     9181 tataaaattg aaaaataaaa aaaacgacta ttccaaacta gaacgaaaac tttacatgta
     9241 tatcgttgca attgttgtgg tagcaattgt attcgtgttg tatattcgtt caatgatccg
     9301 agggaaactt ggggattgga tcttaagtat tttggaaaac aaatatgact taaatcacct
     9361 ggacgcgatg aaattatatc aatattccat acggaacaat atagatatct ttatttatgt
     9421 ggcgattgtc attagtattc ttattctatg tcgcgtcatg ctttcaaaat tcgcaaaata
     9481 ctttgacgag ataaataccg gcattgatgt acttattcag aacgaagata aacaaattga
     9541 gctttctgcg gaaatggatg ttatggaaca aaagctcaac acattaaaac ggactctgga
     9601 aaagcgagag caggatgcaa agctggccga acaaagaaaa aatgacgttg ttatgtactt
     9661 ggcgcacgat attaaaacgc cccttacatc cattatcggt tatttgagcc tgcttgacga
     9721 ggctccagac atgccggtag atcaaaaggc aaagtatgtg catatcacgt tggacaaagc
     9781 gtatcgactc gaacagctaa tcgacgagtt ttttgagatt acacggtata acctacaaac
     9841 gataacgcta acaaaaacgc acatagacct atactatatg ctggtgcaga tgaccgatga
     9901 attttatcct cagctttccg cacatggaaa acaggcggtt attcacgccc ccgaggatct
     9961 gaccgtgtcc ggcgaccctg ataaactcgc gagagtcttt aacaacattt tgaaaaacgc
    10021 cgctgcatac agtgaggata acagcatcat tgacattacc gcgggcctct ccggggatgt
    10081 ggtgtcaatc gaattcaaga acactggaag catcccaaaa gataagctag ctgccatatt
    10141 tgaaaagttc tataggctgg acaatgctcg ttcttccgat acgggtggcg cgggacttgg
    10201 attggcgatt gcaaaagaaa ttattgttca gcatggaggg cagatttacg cggaaagcaa
    10261 tgataactat acgacgttta gggtagagct tccagcgatg ccagacttgg ttgataaaag
    10321 gaggggttct gttgcaaagt tttaaataaa gaataaaatc cct
//
LOCUS       DAZKCW010000224         6676 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.102, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000224 DAZKCW010000000
VERSION     DAZKCW010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.102"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            117..782
                     /locus_tag="ACG84Z_002963"
                     /pseudo
     CDS             117..782
                     /locus_tag="ACG84Z_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            818..1063
                     /locus_tag="ACG84Z_002964"
     CDS             818..1063
                     /locus_tag="ACG84Z_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFP9163713.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            1166..2035
                     /locus_tag="ACG84Z_002965"
     CDS             1166..2035
                     /locus_tag="ACG84Z_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFP9163714.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLLECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            2016..2750
                     /locus_tag="ACG84Z_002966"
     CDS             2016..2750
                     /locus_tag="ACG84Z_002966"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFP9163715.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2783..3691
                     /locus_tag="ACG84Z_002967"
     CDS             2783..3691
                     /locus_tag="ACG84Z_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFP9163716.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3688..4230
                     /gene="sat4"
                     /locus_tag="ACG84Z_002968"
     CDS             3688..4230
                     /gene="sat4"
                     /locus_tag="ACG84Z_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFP9163717.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            4323..5117
                     /locus_tag="ACG84Z_002969"
                     /note="aph(3')-IIIa"
     CDS             4323..5117
                     /locus_tag="ACG84Z_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFP9163718.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            5393..5524
                     /locus_tag="ACG84Z_002970"
                     /pseudo
     CDS             5393..5524
                     /locus_tag="ACG84Z_002970"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            5600..6345
                     /locus_tag="ACG84Z_002971"
                     /pseudo
     CDS             5600..6345
                     /locus_tag="ACG84Z_002971"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6456..6635
                     /locus_tag="ACG84Z_002972"
                     /pseudo
     CDS             6456..6635
                     /locus_tag="ACG84Z_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636358.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibD"
BASE COUNT         2287 a         1005 c         1461 g         1923 t
ORIGIN      
        1 tttccattta gatagtagtg gaaagacctc tatttatctt ttgaaagtga atacaaaaat
       61 aaagcacact ctgctataat ataggtgatt aatccatttg agagaggtgc tttatcatgt
      121 atcaaaatta taccataaac caactttgtt tgcctataga tcttgaaatt aaattagaag
      181 aaaatgattt tgctcatgcc attgtgcagt ttgttgactc tattcccgat gaagtctttc
      241 ttccttatta tcaatctatg ggtagacccc aatatcatcc tcgtatgcta ctttccatta
      301 ttctttgtgc ctatattcaa ggggtttatt cgggccgcca aatacaaaat atgctgatag
      361 atagtattcg gatgcgctac ttatctcaag agcaattccc taactttcgt actattaatc
      421 gttttcgcgt tcatccgatt atgaacgata ttctagatca ttcatttgtt caatttcgtg
      481 agctactggt tcaaagtggc ttaatcagtg gcagtgctct atacattgat ggtacaaaaa
      541 ttgaagcgga tgcgaataaa tactctttcg tttggaaaaa aagtatttta aagtataagg
      601 atagccttga tcaaaaagcc cttgaaaact accaacaaat ggtggaaaca aaaatcttac
      661 ctgagttaat agatgattta aaggatgaac tttctataga agagattgaa aggattcgtc
      721 aatctttgga agaaaaggaa aatcaattaa ttgaagcgat tgaccaaacc gaaacagtag
      781 aagggggctg acccattatt aataaggagt ggacaacatg attgatgtaa atgagctatt
      841 ggaagaagct attagagaaa ctgaaaatct aaatgatggc gaagtttttc ttgttaaaga
      901 tttattcaag ggatatgtgg ggaataggat acccagaaag gatcgacttc tgcttggaac
      961 gttattttta aaccatgtta gcaaaatgaa tggtaattta aaggctattg aaaagacttc
     1021 atctaatcag cagaggtata aaaagacaat tgataagttt taactatctt ttgtgaaatt
     1081 aaaaaaatta taaatatgtt gagtagaagc aaaagatttg gcttggaatt tttacagcag
     1141 tgaatcgata aaaggagcat gcttgatggt agataatatt attaaatcag tagcagagaa
     1201 attatcctct ctgtcttata tagaaggtat tgttttaggt ggttcacgtg caaggggcac
     1261 ccatacagag gattcggata tagatatcgg catctattac aattcagaat catttgacat
     1321 aaatactatt aatcaattcg ctacaaagct ggatgatgag catagaaata accttgttgt
     1381 acctcccgga gcatggggtg attggattaa tggcggcgga tggttagtca taaacgggta
     1441 tcatgtggat ttaattttac gtgatattaa acgtgtggaa caaataatga aagatacaga
     1501 gcacggaatt gttactgcca attatcagac tgggcatccc catggttata ttagtgcaat
     1561 gtatcgagga gaattagcga ttagcaaaat actatatgct aagaatgaaa gcttatgcga
     1621 attaaaaaaa caggcagaaa cttatcccaa tgctttgcag aaaagtttag ttaacttttt
     1681 tatgtttgaa gcagggttct ctttaatgtt tgtaaaagca aattcgggaa cagacgataa
     1741 atattatatt gcgggtcatg tttttcgtat agtttcatgt ttaaatcaag tgttatttgc
     1801 atgtaataat gcttattgta tcaacgaaaa gaaagctata aaactgcttg aaacttttga
     1861 acataaacct gaaaaatata ccgagaaggt aaatcatatt tttgaagtac tcggtatctc
     1921 acttttggaa tgctacgaca tgaccgagaa gctttataat gaagtgaatg aaattgtatc
     1981 ggagataaat aactttttaa acgaggagag ttcagatgaa agaaaacaaa tatgatgata
     2041 atatattttt tcaaaaatac agtcaaatga gtcgctcgca gaaaggactg gctggtgcgg
     2101 gagaatggga gactttgaaa aagatgctac ctgattttaa gggtaagcgt gtgcttgatt
     2161 taggatgcgg ctatggatgg cactgtatat atgcgatgga aaacggtgct tcctctgtag
     2221 taggtgttga tatttctcat aaaatgctcg aagtagcaaa aggaaaaacc cattttccac
     2281 agattgaata tgaatgctgt gccatagaag atgtggattt cccagaggag agctttgatg
     2341 taatactaag ttcgcttgcg tttcattatg tagcagacta tgagaattta ataaaaaaga
     2401 tatataggat gctgaaggct ggtggcaatt tagtttttac agttgaacat cctgttttta
     2461 ctgctcatgg aacacaagac tggtattata acgaaaaagg agaaatactg catttcccgg
     2521 tggacaatta ttattatgag ggcaaacgga cagctatgtt tttggaagaa aaggttacaa
     2581 aatatcatag aacactgacc acatatctaa atacactgct ttcaaatagt tttataataa
     2641 atcagattgt ggagccacag ccgccagaga acatgatgga tattccgggg atggcggatg
     2701 aaatgcgacg cccaatgatg ctgattgtat cggcaaaaaa gaagatgtaa taatatagaa
     2761 aaaataaacg aggagtatgt aaatgagatc agaaaaagaa atgatggatt tagtactttc
     2821 tttagcagaa caggatgaac gtattcgaat tgtgaccctt gaggggtcac gcgcaaatat
     2881 taatatacct aaagatgaat ttcaggatta tgatattaca tattttgtaa gtgatataga
     2941 accgtttata tctaatgatg actggcttaa tcaatttggg aatataataa tgatgcaaaa
     3001 gccggaggat atggaattat tcccacctga agaaaaggga ttttcctatc ttatgctatt
     3061 tgatgattac aataaaattg atcttacctt attgcccttg gaagagttag ataattacct
     3121 aaagggcgat aaattaataa aggttctaat tgataaagat tgtagaatta aaagggacat
     3181 agttccgact gatatagatt atcatgtaag aaagccaagc gcaagggagt atgatgattg
     3241 ctgcaatgaa ttttggaatg taacacctta tgttattaaa ggattgtgcc gtaaggaaat
     3301 tttatttgct attgatcatt ttaatcagat tgttcgccat gagctgctga gaatgatatc
     3361 atggaaggtc ggcatcgaaa caggctttaa attaagtgta ggcaagaact ataagtttat
     3421 tgaaaggtat atatccgagg atttgtggga gaaacttttg tccacctacc ggatggattc
     3481 ctatgaaaac atatgggaag cattatttct atgccatcaa ttgttcaggg cggtatccgg
     3541 tgaggtggcg gaaaggcttc attatgccta tccggagtat gataggaata taacaaaata
     3601 taccagggac atgtataaaa aatacactgg taaaaccggc tgcctggata gcacatatgc
     3661 cgctgatata gaagagaggc gggaacagtg attacagaaa tgaaagcagg gcacctgaaa
     3721 gatatcgata aacccagcga accatttgag gtgataggta agattatacc gaggtatgaa
     3781 aacgagaatt ggacctttac agaattactc tatgaagcgc catatttaaa aagctaccaa
     3841 gacgaagagg atgaagagga tgaggaggca gattgccttg aatatattga caatactgat
     3901 aagataatat atctttacta ccaagacgat aaatgcgtcg gaaaagttaa actgcgaaaa
     3961 aattggaacc ggtacgctta tatagaagat atcgccgtat gtaaggattt cagggggcaa
     4021 ggcataggca gcgcgcttat caatatatct atagaatggg caaagcataa aaacttgcat
     4081 ggactaatgc ttgaaaccca ggacaataac cttatagctt gtaaattcta tcataattgt
     4141 ggtttcaaaa tcggctccgt cgatactatg ttatacgcca actttgaaaa caactttgaa
     4201 aaagctgttt tctggtattt aaggttttag aatgcaagga acagtgaatt ggagttcgtc
     4261 ttgttataat tagcttcttg gggtatcttt aaatactgta gaaaagagga aggaaataat
     4321 aaatggctaa aatgagaata tcaccggaat tgaaaaaact gatcgaaaaa taccgctgcg
     4381 taaaagatac ggaaggaatg tctcctgcta aggtatataa gctggtggga gaaaatgaaa
     4441 acctatattt aaaaatgacg gacagccggt ataaagggac cacctatgat gtggaacggg
     4501 aaaaggacat gatgctatgg ctggaaggaa agctgcctgt tccaaaggtc ctgcactttg
     4561 aacggcatga tggctggagc aatctgctca tgagtgaggc cgatggcgtc ctttgctcgg
     4621 aagagtatga agatgaacaa agccctgaaa agattatcga gctgtatgcg gagtgcatca
     4681 ggctctttca ctccatcgac atatcggatt gtccctatac gaatagctta gacagccgct
     4741 tagccgaatt ggattactta ctgaataacg atctggccga tgtggattgc gaaaactggg
     4801 aagaagacac tccatttaaa gatccgcgcg agctgtatga ttttttaaag acggaaaagc
     4861 ccgaagagga acttgtcttt tcccacggcg acctgggaga cagcaacatc tttgtgaaag
     4921 atggcaaagt aagtggcttt attgatcttg ggagaagcgg cagggcggac aagtggtatg
     4981 acattgcctt ctgcgtccgg tcgatcaggg aggatatcgg ggaagaacag tatgtcgagc
     5041 tattttttga cttactgggg atcaagcctg attgggagaa aataaaatat tatattttac
     5101 tggatgaatt gttttagtac ctagatttag atgtctaaaa agctttaact acaagctttt
     5161 tagacatcta atcttttctg aagtacatcc gcaactgtcc atactctgat gttttatatc
     5221 ttttctaaaa gttcgctaga tagagttcta tattagagat gtaaagagtt ttggtgaaga
     5281 ggtttgtgag tatggctttt ataaccaggg tgcaatgaga agcactaaca gcagctagct
     5341 taagaacgca taggatatac tttttatgga agtcacagag gaggaataaa atttgaacag
     5401 gattaacaga gtaacctcta ttcttattca gctgcaatca aaaaaaataa ttcctgccaa
     5461 agaaattgca cagcgattta atataagctt aaggacagtt tacagagata tccggacact
     5521 tgaagaagcc ggaataccaa ttggatctga ggccggaaaa ggatattttc ttgtagaggg
     5581 cttcctactt ccgccggtaa tgtttacagc ggcggaagtg ggtgcattga ttacagcagg
     5641 gaaattttta aattgccatg gagatgaatc atttataaag gattttgatt cagctatgta
     5701 taaaatcaaa tctattttga agcatggtga aaaaaactat gcacaggagt tggagaacag
     5761 tattaacgtg tacagcacat ctggacagaa aaatacattg gcggataacg ttattgcagc
     5821 aattcagact gcaatctgca ataaaagggt aatatcaatt caatatcctg catcaggagg
     5881 gcaagaaccg gaaagcagaa tgatagagcc tatatcactg gggttttatg aacagaactg
     5941 gtacttaatc ggttttgcag gctaagaaat gaatatagga attttcgtgt ggatcggatt
     6001 aaaagcattt gcatagaaga agagctctgt caaagccatg atggctcttt ggaacaaata
     6061 ttaaaacaaa tgctttcata taaaaaacta tataatgtaa ttcttagagc tgaaaaaggg
     6121 gagacataca attctatcaa gaacaggtat tctctcggct tccttgaaga aaccgatttg
     6181 ggaagtaaaa tggaaatcga attccagaca gattcctttg agatattgag caagcagctg
     6241 attgaatatg gatcaggcat tgaaatagtc caacctgatg aattaaaatg cataacccgt
     6301 aaacacctgg cacaaattac gaatcactgc ctaaacttga tttagagaaa gcgattggtc
     6361 tgttatgtat tttttgtaag gtttcatatc ccctgctgac atacagctgt cagtgtatta
     6421 tgatattcta ctatcaaaaa ggaggattga aaaatatgaa accaaagata attatgcaca
     6481 cacaaattag ccttgatggc cgcattaaag gctttgataa tccggaagtt tactaccagg
     6541 ttgccggggg aattcattcg gatgcggtgc tgtttgggtc caatactgtt tttactgcat
     6601 ttgaaaaata tcctgctgaa acagaggctg attttggata aagtccgtat aattgtgtaa
     6661 aagtaaaaag gccata
//
LOCUS       DAZKCW010000225         5177 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.117, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000225 DAZKCW010000000
VERSION     DAZKCW010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.117"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            2..403
                     /locus_tag="ACG84Z_002973"
     CDS             2..403
                     /locus_tag="ACG84Z_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFP9163719.1"
                     /translation="MLSVFNYHQRSLNLTPFTATGNFREMIDNVIIFIPFGLLLNVNF
                     KEIGFLPKFAFVLVLSLTFEIIQFIFAIGATDITDVITNTVGGFLGLKLYGLSNKHMN
                     QKKLDRVIIFVGILLLVLLLVYRTHLRINYV"
     gene            complement(928..2568)
                     /gene="merA"
                     /locus_tag="ACG84Z_002974"
     CDS             complement(928..2568)
                     /gene="merA"
                     /locus_tag="ACG84Z_002974"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFP9163720.1"
                     /translation="MNQFRMRIQGMTCTGCEKHIEKALESMGALNAKADFSQSEAVFQ
                     LPDDYAIENAIEAVKKINYQPEEVEKLPVQKRVMTNNKEDYDLLIIGSGGAAFSAAIK
                     AVEYGSKVGMIERGTVGGTCVNIGCIPSKTLLRAGEINQSAHVNIFEGLHTSTGEVEL
                     DRLVDQKNELVDDLRKQKYTNLIDDYGFDLIKGEAKFIDENTVTVSGQTYSAQRFLIA
                     TGASPLLPRITGLKEVDYLTSTTLLELRKVPKRLTIIGSGYIGRELGQLFHNLGSEVT
                     LIQRSKRLLKEYDPEISEAMEKALIEQGIKLISGATYERVEQDGNIKKVHIIVNGKNK
                     VIESDELLVGTGRKPNTEVLNLSAAGVQVGPNNEIKINAFAQTSNRKIYAAGDVTLGP
                     QFVYVAAYEGGIAAGNAIGGLNKAIDLSVVPGVSFTSPQFATVGLTQQQAKEKGYEVK
                     KAVLSLENVPRAIVNHNTTGVFKLVVDRKTQKILGVHIVSENAGEVIYGASLAVKFGL
                     TVADLKDTLAPYLTMSEGLKLAALAFDKDISKLSCCAG"
     gene            complement(2582..2980)
                     /gene="merR"
                     /locus_tag="ACG84Z_002975"
     CDS             complement(2582..2980)
                     /gene="merR"
                     /locus_tag="ACG84Z_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004635123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFP9163721.1"
                     /translation="MAYFISSFSEKCGVNKESIRYYERKNLLPEPDRTNSGYRVYSEE
                     DVKRVKFIKHLQEIGFSLNEIYKLLGVVDKDNIRCEGMFEFVSKKEREIQKKIENLNR
                     IEYMLKDLRARCPDEKELYACPIIEVLIEN"
     gene            3297..3848
                     /locus_tag="ACG84Z_002976"
     CDS             3297..3848
                     /locus_tag="ACG84Z_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFP9163722.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            4161..4703
                     /locus_tag="ACG84Z_002977"
     CDS             4161..4703
                     /locus_tag="ACG84Z_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HFP9163723.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         1583 a          976 c          885 g         1733 t
ORIGIN      
        1 tattttatca gtatttaatt atcatcaaag aagtcttaac ttgactccat ttactgctac
       61 tgggaatttc agagagatga tagataatgt tataatcttt attccatttg gcttgctttt
      121 gaatgtcaat tttaaagaaa tcggattttt acctaagttt gcttttgtac tggttttaag
      181 tcttactttt gaaataattc aatttatctt cgctattgga gcgacagaca taacagatgt
      241 aattacaaat actgttggag gctttcttgg actgaaatta tatggtttaa gcaataagca
      301 tatgaatcaa aaaaaattag acagagttat tatttttgta ggtatacttt tgctcgtatt
      361 attgctcgtt taccgtaccc atttaagaat aaattacgtg taagatgtct aaatcaagca
      421 atctgatctt tcatacacat aaagatattg aatgaattgg attagatgga aaacgggatg
      481 tggggaaact cgcccgtagg tgtgaagtga ggggaaaacc ggtgataaag taaaaagctt
      541 acctaacact atagtaacaa agaaagccca attatcaatt ttagtgctga ggaattggtc
      601 tctttaataa atttccttaa cgttgtaaat ccgcattttc ctgacggtac ccctttaagc
      661 ggtagaatcc ttttttgata cgatttaatt atctatatta agcacgtaag gcaacaatcg
      721 catcttcaat aatatcttgc tgcgttgcct aaatgagcaa ttgcgtttct aaatagtctt
      781 ttatttcttc aacctccact agaatagagc tattaattgg cacgtagacg tttgctgatg
      841 tcataatctt caactcctat cgttatagat aataacgaaa gataaaccaa ggtgttacca
      901 gctactacaa gaaactaaat agaaatatta acctgcacaa caagataatt tcgaaatatc
      961 tttatcaaag gctagagctg ctaactttaa gccttctgac attgttagat aaggcgctaa
     1021 agtatctttt aaatcagcta cggtcaatcc aaatttaacg gctaaggatg ctccataaat
     1081 aacttctcct gcattttcag aaacgatatg aactcccaaa atcttctgtg tttttctatc
     1141 aaccacaagt ttaaacaccc ctgtcgtatt atgattgaca atcgctctag gaacattttc
     1201 taatgacaat accgcttttt ttacttcgta tcctttttct ttcgcttgtt gttgtgttaa
     1261 cccaacagtt gcaaattgcg gactggtaaa tgatactcca ggaactaccg ataaatcgat
     1321 tgctttattt aacccaccaa ttgcatttcc tgctgcaatt cctccttcat aggctgctac
     1381 atagacaaac tgaggtccta atgtcacgtc tcctgctgca taaatttttc tattacttgt
     1441 ctgagcaaaa gcatttatct tgatttcatt gtttggccca acttgaacgc ctgctgcgct
     1501 caagttcaat acttctgtat tcggttttct tcctgttcca actagtagct cgtctgactc
     1561 aatgacctta tttttgccgt ttacaataat atgaactttt ttaatatttc cgtcttgctc
     1621 tactcgttca taagttgctc cggaaatgag ctttattcct tgttcgatta aagctttctc
     1681 cattgcttca gaaatctctg gatcatactc ttttaaaagt cgtttgcttc tttgaataag
     1741 ggtaacctca gaacccagat tgtggaagag ctgtcccagt tctcttccaa tataacccga
     1801 tccaataatt gttaatcgtt ttggtacttt tcttagttca aggagggttg tgctagttaa
     1861 ataatctact tctttaagtc cagtaatacg aggtaagagt ggagaagcac ccgttgcgat
     1921 taaaaaccgt tgggcagaat atgtttgccc actaactgtc acagtgtttt cgtcaatgaa
     1981 ttttgcttct cctttaatta aatcaaaacc atagtcgtca attaaattag tgtatttttg
     2041 tttgcgtaaa tcatcaacta gttcattttt ttgatcgact aagcggtcta attctacttc
     2101 tcccgtagaa gtgtgcaatc cttcaaaaat atttacatgt gctgattgat tgatttctcc
     2161 agctcgaagc agcgtttttg aagggataca accaatgttc acacaggttc cgcctacagt
     2221 tccgcgttca atcatgccca cctttgatcc atactcgact gcttttatag ctgctgaaaa
     2281 agctgctcca ccagaaccga taatgagcaa atcataatct tccttgttat tagtcatcac
     2341 gcgtttttga acaggtaact tttctacttc ttcgggctga taatttattt ttttaactgc
     2401 ttctatcgcg ttttctattg catagtcgtc tggtaattga aataccgctt cgctttgact
     2461 gaaatctgct ttagcgttga gagctcccat gctctcaagc gctttttcta tatgtttttc
     2521 acagccagta caggtcattc cttgaatgcg cattctaaat tgattcattt tcctaccccc
     2581 gttaattttc tattaatact tctatgatag gacacgcgta tagttctttt tcatctggac
     2641 atcttgctcg taaatctttt agcatatatt ctattctatt caaattctcg attttttttt
     2701 gaatttctct ttctttctta gagacaaatt caaacatacc ttcacaacga atgttgtctt
     2761 tatctacaac accaagtaat ttataaattt catttaaaga aaagccaatt tcttgtaggt
     2821 gtttaatgaa ttttactcgt tttacatctt cctctgaata aactcgataa ccggaattag
     2881 tccgatcggg ttctggtagt aagttttttc gttcgtaata tcgaatggat tccttattta
     2941 caccacattt ttcagagaag gagctaataa aataagccat gctatcacat ccttttttta
     3001 attataaacc atgtacttag gtacatgtcc aaccaaaaat aatacgaagg ggggaatatc
     3061 attttccttc ttatttactt tcaaaaatga agtgaaaatt aaatgtggta ccaataaatt
     3121 ttgagacttc ttttataata aataatatcg gacctaaata catgaaatta cataaaatca
     3181 tgtatcaaga atcctatcct tatagggttc ttttttttta ctccccctaa acacacgatt
     3241 tcgtgttgta ataactataa tcatgtattc gaacagacta aaaaggaggg attgtcatgg
     3301 gctataatgt tcagccacta cggtcgcaac aggagattaa tgatttttta ttttgcctgc
     3361 gacggaataa aaatgcggaa cgtgacgttt tcttgtttct aattggaatt aacagcggtc
     3421 tgcgcatgtc cgacatcgtt aaactcaaga aaaaagacgt gattacctca aaaaacccgc
     3481 gcatcgtgga gcaaaagaca ggaaaaacac gcattttata cttaagcagc ttacaggact
     3541 tgattcacgg ctataccgca cccttagatc cggaggctta cttgtttccc agtactaagg
     3601 gcggccattt agaagtcaat acggtctacc agatgtttca aaaggtcgcg aagctgttag
     3661 gaagggacga tatcggcacc cacaccctac gaaaaacctt tggttaccac tattacaaga
     3721 aaaccaaaga cgtggccacc ttaatggaaa tctttggtca cagcagcgag aagattacca
     3781 aacgctacat cggaattaat gaagatgaaa tcagtgaaac gttattaaat tttcggttag
     3841 gtttttgatt gtattatata atagataagc acagtaagac ggttataatc acccacagta
     3901 ttggacaaat caaccttttt ttggtatatt atatatacaa atgagagcag gctcatagtc
     3961 aacttgatat aaatccggaa cataagggtc cggcgggtgg cgagcaccaa aactaaactc
     4021 gatacaaatc cggaacgtaa gggtccggcg ggtggcaagc accaaaacta aacctgtaca
     4081 aaaggctgct cttttgagca gcttttttta ttgggaaaaa ggagcattct tcgcacgcgg
     4141 caaaaaaaga atacaaacgc atgtctataa aagagacaac ccaaattacc agacagttaa
     4201 acgcgattta taaggctgct catctcttac aagaacattt tgtagataaa aaagtatcct
     4261 ttgtcggaga agtctcaacg gtagcgatta ttttttcgac aactaatttt atgcacctct
     4321 gtggcattga ttatcgcaga ggcacacact tgttttttca agatgcctta gacaggaaaa
     4381 taaatttaca ggatattcaa atcaaaacgg atgggacgac ctttcagaaa ttacaagtaa
     4441 taggtagcct tgatttatta ttggggaagc atatttctat tgttggcaga ggtgtttact
     4501 cttctcttcg ctatgatgca gctattcgaa caaggaaaaa aatattggct ctgtctttga
     4561 aacaaaacgg attaatctat atccctatct ctttgttaaa cctatcatca aaggaaattg
     4621 gacctggaca aaaagttact ggcattttta gcgaggattt aacatccggg gaacttaaaa
     4681 tgattatgga agtcatcgat taatcattaa tagtgatatg cgacgtcatt ttgaagtaat
     4741 tattctattt tgggttataa aataaagcat tttaagacga tttcaaatca ttcatgtggg
     4801 ttatttatca cggatgagct tgaaatcgtc ttttatacgt atcaaattga aatgttcggc
     4861 atacaatcta tcgttgttac tacattacta attgtcactt gttaaggaac ttggatcctt
     4921 tctaaacatt ccctagagat aaattttact ttatccctcc gttaatatcc aatttaagca
     4981 cctttccgat tcagggttaa tttgcatatc aagtgcagct tgtgttctag taagattagc
     5041 ccttttagtc cggctgagtt gacttatgga tataagatat ggtcatagca aatagatact
     5101 acgtatagtc tgttaattta gtgtcattaa tcttaagttg gataggctac aattaactag
     5161 acagaaaaat taaggtg
//
LOCUS       DAZKCW010000226         4939 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.119, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000226 DAZKCW010000000
VERSION     DAZKCW010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.119"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            251..1519
                     /locus_tag="ACG84Z_002978"
     CDS             251..1519
                     /locus_tag="ACG84Z_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFP9163724.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            2006..2470
                     /locus_tag="ACG84Z_002979"
     CDS             2006..2470
                     /locus_tag="ACG84Z_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFP9163725.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            2454..3083
                     /locus_tag="ACG84Z_002980"
     CDS             2454..3083
                     /locus_tag="ACG84Z_002980"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFP9163726.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            3437..4915
                     /gene="msr(C)"
                     /locus_tag="ACG84Z_002981"
     CDS             3437..4915
                     /gene="msr(C)"
                     /locus_tag="ACG84Z_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFP9163727.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
BASE COUNT         1707 a          852 c          985 g         1395 t
ORIGIN      
        1 cgacgacaca ggaagtataa tccataacgg ataatatcca gagagaatta cttgttaaat
       61 agttattcaa acgaccatca atttaaggcg tgaatggaga agaatattct tcatttacgt
      121 ctttttatgc agaaaaagca aatttattaa aaagaaacaa atgttattta aatatggaca
      181 ttgacttgct tttacttttt tagttacact gttatttagg aaaagtttca taattcaaag
      241 gagaaaaaag atgaaagcaa agaatttatt atttagcgtt attcttttag gaaatctagc
      301 agttgccaac acaacagtgc tagctgaaga atcgacagaa actgtcgcaa ctcagacatc
      361 gagttcttca gaaacaggaa ttgaaaacga tacagaaagt actttgcagt cagctactgt
      421 ctcagaaaat acaatttcaa ccgaagaacc aacaactgaa acaacagaac aaacacaaac
      481 cgaagacagt acatcagcag aagctcagaa caatccagag aatgcagaag aaatcacgaa
      541 ccaattgaca gatgggcaaa cattgacaca tacccatcaa gcagatttgt ctgaattcga
      601 aaactatact ggctatgctt tttatgctcg ctcatctgct aattctcaac aagcgttcat
      661 tgatagtatt gcctcaactg cacaaagttt ggcaagtgcc aatgacttat atgcatcagt
      721 catgattgct caagccatcg ttgaaagtgg ctgggggaac agtactttgg cttctgcccc
      781 taattacaat ctatttggga ttaaaggaag ctataatggc caatctgtta cgatgcctac
      841 ttcggaatat gtgaatgggc aatggattac ggtgaatgcc gcttttagaa aatatccttc
      901 gtacaaagaa tcattgcaag ataacgtaac ggtattgaag acgacttctt ttcagccagg
      961 cgtttactac tattccggtg catggaaaag caatacgaac tcttacaaag atgctacggc
     1021 ttggctaaca ggtcgttatg ccactgcgcc taattatggt tctacattga acaatgtaat
     1081 cgaaacctat aatctgacac agtatgatac agcaccaact tcaacttctc cgatgtatcg
     1141 tctgtataac cgtcatacag gagaacattt atatacattg aatgccggag aaaaaaatta
     1201 tctgccaact gtaggctggg aatatgaagg gattgcttgg caagcaccaa acagcggaca
     1261 acctgtctac cgtttataca atccttacag tggagaccat cattacacaa tggcacaatc
     1321 tgagatcaac tctttaacaa aaatcggttg gcgttatgaa ggtctaagtt tttattctgg
     1381 tggttccaag ccaatttatc gactatttaa tccaaatgaa aaaactggta cccatcacta
     1441 taccttgagt gctaaggaaa gagattggct aacaccgatg ggctggagat atgaaggaat
     1501 aggattttat ggttattaaa aagaggtagt gaaaaagctg ccctgcatca agtagtaaga
     1561 acagccaaac aaaaacagat tttcatgttt tttgtttggt tgaacttatt accgcagatg
     1621 caagtttttg aacaccgttt actcaaaaaa ggttgtgaca acatcttgtc ataacttttt
     1681 tattactgtt taagcatact gatccaattt ctaatattcg acgggattct tgcaaaaggc
     1741 gatttcggaa atttttggcg gtgtaaaatt atctactgca gaagagctat cttctatagt
     1801 ttgataagaa tcaataatct tggttttagc gttgtgcttt ctttatcatt ttttccgttc
     1861 attctacaaa aaatttcttt tctctatact tttctattga gagcgttttt tttattacac
     1921 agctgattct ttgacttttt tcttttttta ttctattatt gacaagtcaa tcgttgacga
     1981 gtcaattatt agaaaggagg aaattatgtc tttagaagag attagtcacc ttttatatca
     2041 aatcaaatta gccgatcaaa aaatcgtcca gatctttgaa gaaaatatcg gtataagtct
     2101 tactagatac gagatcatga tgagactgaa agaagaaaat ccattgctac aaagcagttt
     2161 gcaagaaaag ttgcagattg atcaaggagc agttactcgt catctgaagg tattggaagc
     2221 aaatggctat gtttcgcgtc agagaaatcc tcagaacaac cgggaagtgt atgtagcgct
     2281 aacagaaaaa gcccagaaga aaatcaagca ttgtgaaatg gaccataaag atacaggttc
     2341 cgtgctatcc ccggctttca gcgatgtaga aatgaaacaa tttctaacac ttttagataa
     2401 attgaatacc caactttgca atataacaac agaaacgaaa gaggttaata ataatggaac
     2461 aaaaaaatga tttttcaaca attatgactg gtagaagatc cgttcgcgta tatgatgaaa
     2521 catacaaaat cccacacgaa gaaatgctgg aaatgatcaa agaagcgacg actgcacctt
     2581 cttctgtcaa tatgaaacca tggcgctttg tggtcgctga aagcgaggaa gcaaaagaaa
     2641 tcttgcgtcc tttgatccgt ttcaatacga gacaaaatga tacttcttct gcaatggtca
     2701 tgatttttgg cgatatgcaa tgttacgaat atggcgaaga aatctacaac caagcttacg
     2761 aatcagggaa gatgccaaaa gaagtcagag atcaacaatt agctgcgatc attccttatt
     2821 acaagagttt ttcaagagaa gaaatgaacg atgtagtcaa agtcgattct agcttagcgg
     2881 ctatgcaatt catgttagtt gcgcgtgatc atggctatga aacaaatcca attggtggat
     2941 tcgaagcaga tcagttggca gaggcatttg gtttggataa agaccgttat gttccagtta
     3001 ttattttatc aataggaaaa gcggtagaag aaggttacga gtctgttcgt ttagcaccag
     3061 aaaagatcac tatgttcgaa taaaaggttt tcagttacta ttcagtagct attgcttttt
     3121 ttgaatcgtg tgtggtaacc taataaaaaa ggaggtcgga aaaatgactg catcgatgaa
     3181 attacgtttc gaacttttga ataacaacta aataaattca aaagacatgt ataaacaaca
     3241 atttcatgga tggagtatgt ccattttttc gaacgacagt agaataggtg aaagctatga
     3301 cagatttggt gatttagtca tagttatttc gttcagagta ggaaaagatg tgatgcagtt
     3361 tttttgcaaa cagatttttc tgctcttttt tagtatcgat aattgttgtt ttacatgaaa
     3421 taggagtgta aaacatatgg aaaatttagc agtaaatata acaaatctac aagtcagctt
     3481 tggcaaccag ctagaactat ctattgattc tcttcgtgtc tatcagcaag atcgtatagg
     3541 gatcatagga gaaaatggtg tcggtaaatc gactttgctc aaactaatag ccggtgaact
     3601 ttttcccgat catgggaaaa tccaaacaga gatcaccttc aactacctgc ctcaattaac
     3661 ctatctcgct gaagcaaagg acctaaattt ggaattagcc agtcatttcc agttaagact
     3721 ggaagaaact tcagagcgga aatggagcgg aggggaagaa cgaaagatcg agttgatacg
     3781 tcttctttct tcttatgaac aagggatgct tctagacgag ccaacaaccc atctagatag
     3841 aaaaagtatt gatcgactga ttgaagagct tcgttattat tatggtacgc tggtttttgt
     3901 tagtcatgat cgctattttc tagatgagct agcatcgaaa atctgggaag taaaagacgg
     3961 agaaatccga gagttttcgg ggaattatag tgcctatctc actcaaaagg aattggagaa
     4021 aaagactcag ctacgagaag cagagtcgat catgaaagag aaaaaacgat tggaaaaatc
     4081 gatccaagaa aagaaaaaac aagcggaaaa gttggaaaaa gtgtccagta aaaagaaaaa
     4141 gcaacaaatc agactggatc ggttgtcttc ctctaaacaa aaagacagtg tacaaaaagc
     4201 catccaaaag aatgcgaaaa cattagagag aagactccaa aaaataggag aaacaaccaa
     4261 gccgcagcag atgaaacaaa tccgttttcc agtaccaaaa tctcttgaac tccacagccg
     4321 ctatcccatc atgggacaaa atgtccaatt ggaaagaagt gggagaacat tactggtaaa
     4381 tggtgatttt cagttttctt taggtaaaaa aatcgcgatt gtcggtgaaa atggttcagg
     4441 taagacaacc ttattagaac atatccgcaa acaaggagaa ggaatccttc tctctccgaa
     4501 agtaagcttt caagtatatc agcaaaaggg ttatcaaatg acatctgaag aatccatcat
     4561 tcgttttgtc atgagacaaa cagagttttc agaatcgctt gtccgtagtt tgctgaatca
     4621 cttagggttt gctcaggaaa ctttgacgaa accgttatgt acattaagtg ggggagaagc
     4681 gacccgtctg acgattgctt tgctttttac taagccaagt aatgtgttgc tgttagatga
     4741 accgactaat tttattgata tggcaacgat cgaagcttta gagaagctaa tgcaaatata
     4801 tccgggaacg attttgttta cttctcatga ttcttacttt gtcgagcgta cggctgatga
     4861 agtttatgaa ataaaagggc agaaaataaa aaaagtactt acgagaaatt tttaaatgtg
     4921 ctacgatgat tttcgtgac
//
LOCUS       DAZKCW010000227         2930 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.142, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000227 DAZKCW010000000
VERSION     DAZKCW010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.142"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            188..1156
                     /locus_tag="ACG84Z_002982"
     CDS             188..1156
                     /locus_tag="ACG84Z_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFP9163728.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1149..2180
                     /gene="vanA"
                     /locus_tag="ACG84Z_002983"
     CDS             1149..2180
                     /gene="vanA"
                     /locus_tag="ACG84Z_002983"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFP9163729.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2186..2794
                     /locus_tag="ACG84Z_002984"
     CDS             2186..2794
                     /locus_tag="ACG84Z_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFP9163730.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          865 a          564 c          711 g          790 t
ORIGIN      
        1 ctcaaggtta tctttacttt ttcttaggaa attaacaatt taatattaag aaacggctcg
       61 ttcttacacg gtagacttaa taccgtaaga acgagccgtt ttcgttcttc agagaaagat
      121 ttgacaagat taccattggc atccccgttt tatttggtgc ctttcacaga aagggttggt
      181 cttaattatg aataacatcg gcattactgt ttatggatgt gagcaggatg aggcagatgc
      241 attccatgct ctttcgcctc gctttggcgt tatggcaacg ataattaacg ccaacgtgtc
      301 ggaatccaac gccaaatccg cgcctttcaa tcaatgtatc agtgtgggac ataaatcaga
      361 gatttccgcc tctattcttc ttgcgctgaa gagagccggt gtgaaatata tttctacccg
      421 aagcatcggc tgcaatcata tagatacaac tgctgctaag agaatgggca tcactgtcga
      481 caatgtggcg tactcgccgg atagcgttgc cgattatact atgatgctaa ttcttatggc
      541 agtacgcaac gtaaaatcga ttgtgcgctc tgtggaaaaa catgatttca ggttggacag
      601 cgaccgtggc aaggtactca gcgacatgac agttggtgtg gtgggaacgg gccagatagg
      661 caaagcggtt attgagcggc tgcgaggatt tggatgtaaa gtgttggctt atagtcgcag
      721 ccgaagtata gaggtaaact atgtaccgtt tgatgagttg ctgcaaaata gcgatatcgt
      781 tacgcttcat gtgccgctca atacggatac gcactatatt atcagccacg aacaaataca
      841 gagaatgaag caaggagcat ttcttatcaa tactgggcgc ggtccacttg tagataccta
      901 tgagttggtt aaagcattag aaaacgggaa actgggcggt gccgcattgg atgtattgga
      961 aggagaggaa gagtttttct actctgattg cacccaaaaa ccaattgata atcaattttt
     1021 acttaaactt caaagaatgc ctaacgtgat aatcacaccg catacggcct attataccga
     1081 gcaagcgttg cgtgataccg ttgaaaaaac cattaaaaac tgtttggatt ttgaaaggag
     1141 acaggagcat gaatagaata aaagttgcaa tactgtttgg gggttgctca gaggagcatg
     1201 acgtatcggt aaaatctgca atagagatag ccgctaacat taataaagaa aaatacgagc
     1261 cgttatacat tggaattacg aaatctggtg tatggaaaat gtgcgaaaaa ccttgcgcgg
     1321 aatgggaaaa cgacaattgc tattcagctg tactctcgcc ggataaaaaa atgcacggat
     1381 tacttgttaa aaagaaccat gaatatgaaa tcaaccatgt tgatgtagca ttttcagctt
     1441 tgcatggcaa gtcaggtgaa gatggatcca tacaaggtct gtttgaattg tccggtatcc
     1501 cttttgtagg ctgcgatatt caaagctcag caatttgtat ggacaaatcg ttgacataca
     1561 tcgttgcgaa aaatgctggg atagctactc ccgccttttg ggttattaat aaagatgata
     1621 ggccggtggc agctacgttt acctatcctg tttttgttaa gccggcgcgt tcaggctcat
     1681 ccttcggtgt gaaaaaagtc aatagcgcgg acgaattgga ctacgcaatt gaatcggcaa
     1741 gacaatatga cagcaaaatc ttaattgagc aggctgtttc gggctgtgag gtcggttgtg
     1801 cggtattggg aaacagtgcc gcgttagttg ttggcgaggt ggaccaaatc aggctgcagt
     1861 acggaatctt tcgtattcat caggaagtcg agccggaaaa aggctctgaa aacgcagtta
     1921 taaccgttcc cgcagacctt tcagcagagg agcgaggacg gatacaggaa acggcaaaaa
     1981 aaatatataa agcgctcggc tgtagaggtc tagcccgtgt ggatatgttt ttacaagata
     2041 acggccgcat tgtactgaac gaagtcaata ctctgcccgg tttcacgtca tacagtcgtt
     2101 atccccgtat gatggccgct gcaggtattg cacttcccga actgattgac cgcttgatcg
     2161 tattagcgtt aaaggggtga taagcatgga aataggattt acttttttag atgaaatagt
     2221 acacggtgtt cgttgggacg ctaaatatgc cacttgggat aatttcaccg gaaaaccggt
     2281 tgacggttat gaagtaaatc gcattgtagg gacatacgag ttggctgaat cgcttttgaa
     2341 ggcaaaagaa ctggctgcta cccaagggta cggattgctt ctatgggacg gttaccgtcc
     2401 taagcgtgct gtaaactgtt ttatgcaatg ggctgcacag ccggaaaata acctgacaaa
     2461 ggaaagttat tatcccaata ttgaccgaac tgagatgatt tcaaaaggat acgtggcttc
     2521 aaaatcaagc catagccgcg gcagtgccat tgatcttacg ctttatcgat tagacacggg
     2581 tgagcttgta ccaatgggga gccgatttga ttttatggat gaacgctctc atcatgcggc
     2641 aaatggaata tcatgcaatg aagcgcaaaa tcgcagacgt ttgcgctcca tcatggaaaa
     2701 cagtgggttt gaagcatata gcctcgaatg gtggcactat gtattaagag acgaaccata
     2761 ccccaatagc tattttgatt tccccgttaa ataaactttt aaccgttgca cggacaaact
     2821 atataagcta actctttcgg caggaaaccc gacgtatgta actggttctt agggaattta
     2881 tatatagtag ataacccgtg gtgctagtta attttaatat cctaaagaat
//
LOCUS       DAZKCW010000228         2566 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.148, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000228 DAZKCW010000000
VERSION     DAZKCW010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.148"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(40..342)
                     /locus_tag="ACG84Z_002985"
                     /pseudo
     CDS             complement(40..342)
                     /locus_tag="ACG84Z_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            435..784
                     /locus_tag="ACG84Z_002986"
                     /pseudo
     CDS             435..784
                     /locus_tag="ACG84Z_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1056..1346)
                     /locus_tag="ACG84Z_002987"
     CDS             complement(1056..1346)
                     /locus_tag="ACG84Z_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFP9163731.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1554..2245)
                     /locus_tag="ACG84Z_002988"
                     /pseudo
     CDS             complement(1554..2245)
                     /locus_tag="ACG84Z_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          759 a          472 c          356 g          979 t
ORIGIN      
        1 tatggatttt ttcatttaca caaaatattt tatactctca acatacttgc aaagtaatac
       61 tacaattcct aacataatcg tagaatttaa taatttccat agcataaagt gtttagaaaa
      121 gaacattaag aatagttcta taataattct tgaactccat gtcttataat gttctatcga
      181 agcacccaaa tagccaagtt catctaatct acttgcataa actacgtcat ccgctctcat
      241 agtcggcata tacatattaa agagtaaaaa gataccccaa atccctatta gtaacaagat
      301 cagttctttg ttattcgtta tttttctatt atgtttgttc atttttatac tccttcttat
      361 atttcctaat agagtataac atagctttaa gcattactta aagataactt aaaagttatc
      421 ttttaaatac ttaattgtta aataccttat ttgatgcaaa agaaatctac gatagtcaac
      481 aaaaaaattt tcattatatc cagaaaaatt tttcttagtt aaggacctat ggattgcagt
      541 aatgcagaat tcgtcgaata aactgccaaa gacatacaat catattgctt ttaaaattga
      601 cgaacaagat atagattcgt ttgtctcaaa aatccaaatg ttaggtttaa ctgtcgaacc
      661 aggacgttct cgtgtgaaag gcgaggcttc ttcaatttac ttttacgact atgataatca
      721 cctcttcgag ttacataccg gtactctcca ggaacgttta aaatcctaca attccactac
      781 ctgagactag taatgactag tctcttttta tggcctctga tccccccatt gagcgaatac
      841 taatagggct tcgaattgat ctgttcaatc tttaagcaat atccctcaaa tgagtttgga
      901 aagtttagtg attcatcaca aatacttaaa tacatgtagt tatatataga ttgaggttct
      961 tgtgagcgta tgctcgtgtg ggttcaaatc ccatcgtctg catccatctt tccaaaacaa
     1021 gcggctagga catttttgtc tcagccgctt gttttctagt ttattctttc atcttgtcgg
     1081 accttttttc ttgggtatag acttttctca tattctacca caattttggg tttccctaac
     1141 acatgatagg atctcacaac aaattgcttt ctattattat aataacctgt aacgactaac
     1201 ttcatccctt cgtctacttc agctaggaag ttcaaactat gggaagcaat caaacaattg
     1261 accccattta aactgaaacg gatcaacggt ctggcactaa cttgcaaagt acggatctta
     1321 tctactgttc catatttttt ctccataacc ttcacctcaa taccattata cgaacataca
     1381 ttccctttgt aaagaagaaa ctctgtttta tctttttgac tttttgtcta ttacctttct
     1441 taaaatcata ttggcacttc ctgcgaagat gaaggacatg tactaaaaaa aagaggcagc
     1501 agtatagatt actgttgctt ctttactaat ttaggtttac ttgttaagaa agattattta
     1561 cgcaaatgtt cttcaacaat ttgctgagat ttatcagctg tatcttccac ttcatctttt
     1621 gctttttcta acttttgaat atattgtttc aagcttgagt tttcagcagt tgcttcgtct
     1681 aatttctttt gtgtatctgt taactgattt ctacatttgt tttttcttgt gtcagtgttg
     1741 cgatttgttg attcaaacca tttacagtat tttgtaattc tgaaagtttt gcttgtgctt
     1801 cttgtagtct tgctgtccaa tctgcattca gatgattgat ttcatcattt ttttggttga
     1861 tctcatctag tttgacattg atttcatttt gtttgctttg tagttgtgca tccttgctga
     1921 ctaattgact ttctaagttt tgtttttctg ctgccgattg atttttttgg ttttctaatt
     1981 catttacttt tgtttggtat tcttggacat ctgcctttga atcttgcaat gtctgttctt
     2041 tttgtgctag tcgagcggta agatctgtaa tcgcttgctc tttatctgtc aatgtatgat
     2101 caagctgtgt cagattctca ttgattgtat caatatctgt ctctccaccc cacaaaataa
     2161 tttcatttgc gtaccgcgtg cctgtgtagc caattagaca tagaaatgca acgacaatcc
     2221 caccagtaat aaatttcttt ttcatttgca tagctcctta atccaatact tttacatgct
     2281 aaaagtaagt gatctcaaac acaatgtcaa gcgtttttaa attacatatg taattttaat
     2341 ataaatacta tcaaatactc atttaatcct ccttttttat ctatttaaaa aatctttttt
     2401 atagagaaaa atgcaggtta atactttctt aaataaatat ttatggtgaa caaaaacaaa
     2461 aaagcaagtt ttattaaacg taaccctttt catttcatag attactgtat ttattacaaa
     2521 aaacgcggat ttgtcataaa ttgtcatgct tcttttacct atgaaa
//
LOCUS       DAZKCW010000229         1531 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.178, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000229 DAZKCW010000000
VERSION     DAZKCW010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.178"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            111..194
                     /locus_tag="ACG84Z_002989"
     CDS             111..194
                     /locus_tag="ACG84Z_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFP9163732.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="ACG84Z_002990"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="ACG84Z_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFP9163733.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1226..1486
                     /locus_tag="ACG84Z_002991"
                     /pseudo
     CDS             1226..1486
                     /locus_tag="ACG84Z_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
BASE COUNT          582 a          242 c          259 g          448 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta cagatgtaat
      301 cacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 actcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttttaaatt
     1081 tggaaagtta cacgttacta aagggaatgg agataaatta ttagatatac tactgacagc
     1141 ttccaagaag ctaaagaggt ccctagcgcc tacggggaat ttgtatcgat aaggggtaca
     1201 aattcccact aagcgctcgg gaccccttgt aggaaaatgt cctaagtgtg gcaacaatat
     1261 tgtattaaaa aaatcgtttt atggttgttc aaattatcct gaatgtaagt ttactttagc
     1321 tgaacatttt agaaagaaaa aactaaccaa aacgaatgta aaagaattac tggagggaaa
     1381 agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag ccctacaatg ccgttgtaaa
     1441 aattggggaa aagggatata ttgattttat ctctttttca aaataaacat ggggctgacc
     1501 caaaagtagc tcctatatga aaaatagagg t
//
LOCUS       DAZKCW010000230         1356 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.188, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000230 DAZKCW010000000
VERSION     DAZKCW010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.188"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            193..1104
                     /locus_tag="ACG84Z_002992"
     CDS             193..1104
                     /locus_tag="ACG84Z_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFP9163734.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT          494 a          183 c          270 g          409 t
ORIGIN      
        1 acgtgagttg aaattttgac aacctaattt ttctaaggaa attggtgata atagtaaatc
       61 cagtagggcg aaataattga ctgtaattta cggggcaaaa cggcacaatc tcaaacgaga
      121 ttgtgccgtt taaggggaag attctagaaa tatttcatac ttccaactat atagttaagg
      181 aggagactga aaatgaagaa gttgtttttt ttattgttat tgttattctt aatatactta
      241 ggttatgact acgttaatga agcactgttt tctcaggaaa aagtcgaatt tcaaaattat
      301 gatcaaaatc ccaaagaaca tttagaaaat agtgggactt ctgaaaatac ccaagagaaa
      361 acaattacag aagaacaggt ttatcaagga aatctgctat taatcaatag taaatatcct
      421 gttcgccaag aaagtgtgaa gtcagatatc gtgaatttat ctaaacatga cgaattaata
      481 aatggatacg ggttgcttga tagtaatatt tatatgtcaa aagaaatagc acaaaaattt
      541 tcagagatgg tcaatgatgc tgtaaagggt ggcgttagtc attttattat taatagtggc
      601 tatcgagact ttgatgagca aagtgtgctt taccaagaaa tgggggctga gtatgcctta
      661 ccagcaggtt atagtgagca taattcaggt ttatcactag atgtaggatc aagcttgacg
      721 aaaatggaac gagcccctga aggaaagtgg atagaagaaa atgcttggaa atacgggttc
      781 attttacgtt atccagagga caaaacagag ttaacaggaa ttcaatatga accatggcat
      841 attcgctatg ttggtttacc acatagtgcg attatgaaag aaaagaattt cgttctcgag
      901 gaatatatgg attacctaaa agaagaaaaa accatttctg ttagtgtaaa tggggaaaaa
      961 tatgagatct tttattatcc tgttactaaa aataccacca ttcatgtgcc gactaatctt
     1021 cgttatgaga tatcaggaaa caatatagac ggtgtaattg tgacagtgtt tcccggatca
     1081 acacatacta attcaaggag gtaaggatgg cggaatgaaa ccaacgaaat taatgaacag
     1141 cattattgta ctagcacttt tggggtaacg ttagcttttt aatttaaaac ccacgttaac
     1201 taggacattg ctatactaat gatacaactt aaacaaaaga attagaggaa attatattgg
     1261 gaaaaatatt atctagagga ttgctagctt tatatttagt gacactaatc tggttagtgt
     1321 tattcaaatt acaatacaat attttatcag tattta
//
LOCUS       DAZKCW010000231         1219 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.192, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000231 DAZKCW010000000
VERSION     DAZKCW010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.192"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            47..439
                     /locus_tag="ACG84Z_002993"
     CDS             47..439
                     /locus_tag="ACG84Z_002993"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFP9163735.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            440..1183
                     /gene="aac(6')-Ie"
                     /locus_tag="ACG84Z_002994"
                     /pseudo
     CDS             440..1183
                     /gene="aac(6')-Ie"
                     /locus_tag="ACG84Z_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
BASE COUNT          498 a          100 c          214 g          407 t
ORIGIN      
        1 aacattgtat agcattttac acaggagtct ggacttgact gagtttatgg aagaagtttt
       61 aattgatgat aatatggttt ttgatattga taatttaaaa ggatttctta atgataccag
      121 ttcatttggg tttatagcta aagaaaataa taaaattata ggatttgcat attgctatac
      181 acttttaaga cctgatggaa aaacaatgtt ttatttacac tcaataggaa tgttacctaa
      241 ctatcaagac aaaggttatg gttcaaaatt attatctttt attaaggaat attctaaaga
      301 gattggttgt tctgaaatgt ttttaataac tgataaaggt aatcctagag cttgccatgt
      361 atatgaaaaa ttaggtggta aaaatgatta taaagatgaa atagtatatg tatatgatta
      421 tgaaaaaggt gataaataaa tgaatatagt tgaaaatgaa atatgtataa gaactttaat
      481 agatgatgat tttcctttga tgttaaaatg gttaactgat gaaagagtat tagaatttta
      541 tggtggtaga gataaaaaat atacattaga atcattaaaa aaacattata cagagccttg
      601 ggaagatgaa gtttttagag taattattga atataacaat gttcctattg gatatggaca
      661 aatatataaa atgtatgatg agttatatac tgattatcat tatccaaaaa ctgatgagat
      721 agtctatggt atggatcaat ttataggaga gccaaattat tggagtaaag gaattggtac
      781 aagatatatt aaattgattt ttgaattttt gaaaaaagaa agaaatgcta atgcagttat
      841 tttagaccct cataaaaata atccaagagc aataagggca taccaaaaat ctggttttag
      901 aattattgaa gatttgccag aacatgaatt acacgagggc aaaaaagaag attgttattt
      961 aatggaatat agatatgatg ataatgccac aaatgttaag gcaatgaaat atttaattga
     1021 gcattacttt gataatttca aagtagatag tattgaaata atcggtagtg gttatgatag
     1081 tgtggcatat ttagttaata atgaatacat ttttaaaaca aaatttagta ctaataagaa
     1141 aaaaggttat gcaaaagaaa aagcaatata taatttttta aacgccgatt gtaaaattaa
     1201 gctagacaac taaaaaaag
//
LOCUS       DAZKCW010000232          897 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.203, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000232 DAZKCW010000000
VERSION     DAZKCW010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.203"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            284..832
                     /gene="aac(6')"
                     /locus_tag="ACG84Z_002995"
     CDS             284..832
                     /gene="aac(6')"
                     /locus_tag="ACG84Z_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFP9163736.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          316 a          134 c          185 g          262 t
ORIGIN      
        1 tatggccttt ttacttttac acaattatac ggactttatc gtttttttta aagcaaaaga
       61 taatctatat catgatgaac aaacagagtt ttttcctcca attgatggct ttcctgatct
      121 ttcctatttt gaataaagtg tttctgtata atttttttat tttataagta agataaataa
      181 tgaaagaata gagatactga ttggtagcta aagatttttg agcgagaaca tttcgttttt
      241 tcaaaaggac tgttagaata agcaagaaca agggggaaga cgtatgataa tcagtgaatt
      301 tgaccgtaat aatccagtat tgaaagatca gctttctgat ttactgagac tgacttggcc
      361 ggaagaatat ggagacagct cggcagaaga agtagaagaa atgatgaatc cagaacgaat
      421 cgcggtagca gcggtagacc aagatgagtt agtaggattt attggtgcaa tccctcaata
      481 cggtatcaca ggttgggaat tgcatccatt agttgtagaa agctcccgac gaaagaacca
      541 aataggtact cgattagtca attacttaga aaaagaagta gcttccagag gaggaatcac
      601 gatttattta ggtacggatg atttagacca tggaacaacg ttaagtcaaa cggacctgta
      661 tgagcataca tttgataaag tggcttccat ccagaacctt cgtgaacatc cgtatgaatt
      721 ctatgaaaaa ttaggttata aaatcgtagg tgtcttacca aatgcaaatg gctgggacaa
      781 accggatatt tggatggcaa aaacgattat tcctcgacca aattctcaat aataaaaaga
      841 ggttgtgaca gaagtaatca gcttcaagaa ataagaagga atttacgaaa attactt
//
LOCUS       DAZKCW010000233          854 bp    DNA     linear   BCT 23-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE4130
            SAMEA115707023-rid22582603.guided.206, whole genome shotgun
            sequence.
ACCESSION   DAZKCW010000233 DAZKCW010000000
VERSION     DAZKCW010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707023
            Sequence Read Archive: ERR13196755
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002287855.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002287855.1
            Genome Coverage       :: 142x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:29:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,996
            CDSs (total)                      :: 2,935
            Genes (coding)                    :: 2,848
            CDSs (with protein)               :: 2,848
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2, 1 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 87
            CDSs (without protein)            :: 87
            Pseudo Genes (ambiguous residues) :: 0 of 87
            Pseudo Genes (frameshifted)       :: 41 of 87
            Pseudo Genes (incomplete)         :: 42 of 87
            Pseudo Genes (internal stop)      :: 17 of 87
            Pseudo Genes (multiple problems)  :: 9 of 87
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707023-rid22582603.guided.206"
                     /isolate="VRE4130"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            37..735
                     /locus_tag="ACG84Z_002996"
                     /pseudo
     CDS             37..735
                     /locus_tag="ACG84Z_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase family
                     protein"
BASE COUNT          368 a           63 c          141 g          282 t
ORIGIN      
        1 aagatgattt gtctaactta atttgacaaa cgaaaaaata caaatttaga aactaatgta
       61 aaaattccta atattgaata ttcgtatatt agtgatgaat tatctatact aggttataaa
      121 gaaattaaag gaactttttt aacaccagaa atttattcta ctatgtcaga agaagaacaa
      181 aatttgttaa aacgagatat tgccagtttt ttaagacaaa tgcacggttt agattataca
      241 gatattagtg aatgtactat tgataataaa caaaatgtat tagaagagta tatattgttg
      301 cgtgaaacta tttataatga tttaactgat atagaaaaag attatataga aagttttatg
      361 gaaagactaa atgcaacaac agtttttgag ggtaaaaagt gtttatgcca taatgatttt
      421 agttgtaatc atctattgtt agatggcaat aatagattaa ctggaataat tgattttgga
      481 gattctggaa ttatagatga atattgtgat tttatatact tacttgaaga tagtgaagaa
      541 gaaataggaa caaattttgg agaagatata ttaagaatgt atggaaatat agatattgag
      601 aaagcaaaag aatatcaaga tatagttgaa gaatattatc ctattgaaac tattgtttat
      661 ggaattaaaa atattaaaca ggaatttatc gaaaatggta gaaaagaaat ttataaaagg
      721 gcttataaag attgattata taatatatga aaagctatta taaaagacat tagtattaaa
      781 tagtttaaaa aaatgaaaaa taataaagga agtgagtcaa gtccagactc ctgtgtaaaa
      841 tgctatacaa tgtt
//
